ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A01 compound treatment 0.226 -0.0114 -0.16 0.264 0.0335 0.56 0.2822 0.4825 3122231 ChemDiv3_011617 Cc1ccc2nc3ccc(NCc4ccccc4)nn3c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A02 compound treatment 0.253 0.0156 0.22 0.264 0.0335 0.56 0.5552 0.9184 3035094 ChemDiv3_011618 O=S(=O)(N1CCNCC1)c2ccc(cc2)n3cnnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A03 compound treatment 0.248 0.0106 0.15 0.275 0.0445 0.75 0.6352 0.834 3122232 ChemDiv3_011619 O=C(Nc1ccccc1)N2CCC3(CC2)OCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A04 compound treatment 0.268 0.0306 0.44 0.255 0.0245 0.41 0.6001 0.9995 3035097 ChemDiv3_011620 Cc1cc(NC(=O)COCC(=O)O)ccc1n2cnnn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A05 compound treatment 0.242 0.00462 0.07 0.262 0.0315 0.53 0.4203 0.7895 3122233 ChemDiv3_011621 CCN/C(=N/c1cc(n[nH]1)c2ccccc2)/SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A06 compound treatment 0.28 0.0426 0.61 0.248 0.0175 0.29 0.6384 0.9437 3122234 ChemDiv3_011622 COc1ccc(Cc2nc3c4cnn(c5c(F)c(F)cc(F)c5F)c4ncn3n2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A07 compound treatment 0.247 0.00962 0.14 0.25 0.0195 0.33 0.3284 0.9262 3035099 ChemDiv3_011623 O=c1c(C#N)cc2c(=O)n3ccccc3nc2n1Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A08 compound treatment 0.167 -0.0704 -1.01 0.143 -0.0875 -1.47 -1.7506 -0.983 3122235 ChemDiv3_011624 CSc1ncc(Cl)c(n1)C(=O)Nc2nnc(SCc3ccc(F)cc3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A09 compound treatment 0.263 0.0256 0.37 0.301 0.0705 1.18 1.0955 0.8847 3122236 ChemDiv3_011625 COc1ccc(cc1)C(O)(CCc2ccccc2)C(CN3CCCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A10 compound treatment 0.279 0.0416 0.6 0.263 0.0325 0.54 0.8063 0.999 3035102 ChemDiv3_011626 OCCCN1C(=O)c2oc3ccccc3c(=O)c2C14C(=O)N(CC=C)c5ccccc54 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A11 compound treatment 0.215 -0.0224 -0.32 0.284 0.0535 0.9 0.4083 0.4285 3122237 ChemDiv3_011627 O=S(=O)(NCC(Nc1ccccc1)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A12 compound treatment 0.211 -0.0264 -0.38 0.274 0.0435 0.73 0.2491 0.3033 3035104 ChemDiv3_011628 Cc1ccc(/C=C/C(=O)N(Cc2ccccc2)c3ccccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A13 compound treatment 0.252 0.0146 0.21 0.238 0.00747 0.13 0.2366 0.97 1127418 ChemDiv3_011629 Clc1ccc(cc1)S(=O)(=O)NC2CCCCC2N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A14 compound treatment 0.263 0.0256 0.37 0.24 0.00947 0.16 0.3716 0.93 3035105 ChemDiv3_011630 CCCCn1c(CCNC(=O)c2ccco2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A15 compound treatment 0.236 -0.00138 -0.02 0.24 0.00947 0.16 0.0985 0.6149 3122238 ChemDiv3_011631 O=C(COc1ccccc1)Oc2cc(c3ccccc3)c4oc(=O)sc4c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A16 compound treatment 0.275 0.0376 0.54 0.266 0.0355 0.6 0.8015 0.9987 3122239 ChemDiv3_011632 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)N2CCC(CC2)(C#N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A17 compound treatment 0.266 0.0286 0.41 0.221 -0.00953 -0.16 0.1764 0.4013 1868441 ChemDiv3_011633 COc1ccccc1NC(=O)Cc2coc3c(C)c(C)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A18 compound treatment 0.256 0.0186 0.27 0.212 -0.0185 -0.31 -0.0316 -0.077 3035136 ChemDiv3_011634 CC(C)(C)OC(=O)N1CCC(CC1)Nc2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A19 compound treatment 0.225 -0.0124 -0.18 0.196 -0.0345 -0.58 -0.535 -0.8828 3035138 ChemDiv3_011635 CC(=O)N1C(Sc2nc(C)cc(n2)c3ccccc3)C(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A20 compound treatment 0.258 0.0206 0.3 0.233 0.00247 0.04 0.2379 0.7986 3035140 ChemDiv3_011636 Cc1cc(C)c(C(=O)C/C(=N/O)/C(F)(F)F)c(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A21 compound treatment 0.271 0.0336 0.48 0.259 0.0285 0.48 0.678 1.0 3035141 ChemDiv3_011637 CCOc1cc(cc(OCC)c1OCC)c2nc(no2)c3cc4cc(C)ccc4nc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A22 compound treatment 0.258 0.0206 0.3 0.218 -0.0125 -0.21 0.0599 0.1653 3035143 ChemDiv3_011638 CC(C)Oc1ccc(CNC(=O)c2oc3ccc4OC(C)(C)C=Cc4c3c2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A23 mock treatment 0.251 0.0136 0.19 0.23 -5.31E-4 -0.01 0.1315 0.6741 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 A24 mock treatment 0.221 -0.0164 -0.23 0.234 0.00347 0.06 -0.1245 -0.5157 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B01 compound treatment 0.285 0.0476 0.68 0.232 0.00147 0.02 0.4991 0.7322 3035144 ChemDiv3_011639 CCc1ccc(NC(=O)NC(C)c2c(sc3CCCCc23)n4cccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B02 compound treatment 0.292 0.0546 0.78 0.257 0.0265 0.44 0.8666 0.9642 3122240 ChemDiv3_011640 O=C(CCCn1sc2ccccc2c1=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B03 compound treatment 0.267 0.0296 0.42 0.275 0.0445 0.75 0.8274 0.964 3122241 ChemDiv3_011641 CCCNC(=O)Cn1c2ccccc2c3nc(=O)cc(C)n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B04 compound treatment 0.298 0.0606 0.87 0.264 0.0335 0.56 1.0104 0.9779 3035146 ChemDiv3_011642 CCOC(=O)N1CCC(CC1)NC(=O)CCc2nc(no2)C3=CCN(C)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B05 compound treatment 0.29 0.0526 0.75 0.275 0.0445 0.75 1.06 1.0 3122242 ChemDiv3_011643 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)N4CCc5ccccc45)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B06 compound treatment 0.271 0.0336 0.48 0.308 0.0775 1.3 1.2595 0.9085 3122429 ChemDiv3_011644 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B07 compound treatment 0.254 0.0166 0.24 0.296 0.0655 1.1 0.9451 0.8407 3122430 ChemDiv3_011645 CC1CCCCC1NC(=O)C2CCN(Cc3cnn(c3n4cccc4)c5ccccc5)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B08 compound treatment 0.275 0.0376 0.54 0.279 0.0485 0.81 0.9558 0.9799 3035149 ChemDiv3_011646 CCOC(=O)c1cc(cn1C)S(=O)(=O)NC(C)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B09 compound treatment 0.269 0.0316 0.45 0.263 0.0325 0.54 0.7052 0.9957 3035151 ChemDiv3_011647 CC1=C(c2ccc(C)cc2)S(=O)(=O)N=C1NC3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B10 compound treatment 0.303 0.0656 0.94 0.271 0.0405 0.68 1.144 0.9874 3122431 ChemDiv3_011648 CC(C)CCNS(=O)(=O)c1cc(Br)cnc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B11 compound treatment 0.26 0.0226 0.32 0.274 0.0435 0.73 0.7447 0.9331 3122432 ChemDiv3_011649 CC1CN(C(=O)CCC(=O)N2CCC3(CC2)OCCO3)c4cc(C)ccc4O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B12 compound treatment 0.265 0.0276 0.4 0.316 0.0855 1.43 1.2938 0.8695 3035153 ChemDiv3_011650 COc1ccc(cc1)c2nnc3n(Cc4ccccc4)c(=O)c5ccccc5n23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B13 compound treatment 0.283 0.0456 0.65 0.307 0.0765 1.28 1.369 0.9508 3122433 ChemDiv3_011651 CCCNC(=O)c1[nH]c2ccccc2c1Sc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B14 compound treatment 0.279 0.0416 0.6 0.269 0.0385 0.65 0.8776 0.9992 3035156 ChemDiv3_011652 CCCCN(C)C(=O)c1noc-2c1COc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B15 compound treatment 0.263 0.0256 0.37 0.198 -0.0325 -0.55 -0.1269 -0.193 3122434 ChemDiv3_011653 COc1ccc2c(Sc3ccccc3)c([nH]c2c1)C(=O)N4CCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B16 compound treatment 0.244 0.00662 0.09 0.302 0.0715 1.2 0.9152 0.7606 3035158 ChemDiv3_011654 COc1ccc(NC(=O)c2nn(C)c-3c2COc4ccccc34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B17 compound treatment 0.26 0.0226 0.32 0.289 0.0585 0.98 0.9227 0.893 3122435 ChemDiv3_011655 CCN1CCN(CC1)C(=O)Cn2nc(C)c3sc4ccccc4c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B18 compound treatment 0.244 0.00662 0.09 0.263 0.0325 0.54 0.4523 0.8178 3035161 ChemDiv3_011656 Cc1ccn2cc(CNC(=O)c3ccccc3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B19 compound treatment 0.302 0.0646 0.92 0.287 0.0565 0.95 1.3238 0.9999 3122436 ChemDiv3_011657 CNC(=O)CCCn1nc(C)c2sc3ccccc3c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B20 compound treatment 0.273 0.0356 0.51 0.267 0.0365 0.61 0.7931 0.9958 3122437 ChemDiv3_011658 O=C(CCCc1ccccc1)NCCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B21 compound treatment 0.29 0.0526 0.75 0.32 0.0895 1.5 1.5941 0.949 3035163 ChemDiv3_011659 CCC(C)NC(=O)C(C)n1sc2ccccc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B22 compound treatment 0.283 0.0456 0.65 0.284 0.0535 0.9 1.096 0.9878 3035198 ChemDiv3_011660 COc1ccc(OC)c(c1)S(=O)(=O)NCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B23 mock treatment 0.32 0.0826 1.18 0.297 0.0665 1.12 1.6245 0.9996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 B24 mock treatment 0.268 0.0306 0.44 0.253 0.0225 0.38 0.5764 0.9972 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C01 compound treatment 0.23 -0.00737 -0.11 0.212 -0.0185 -0.31 -0.2945 -0.8968 3035199 ChemDiv3_011661 Cc1nc2cc(C)c(C)cc2n1CCCNC(=O)Nc3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C02 compound treatment 0.26 0.0226 0.32 0.282 0.0515 0.86 0.8397 0.9102 3035200 ChemDiv3_011662 Cc1c(oc2ccccc12)C(=O)N3CCNCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C03 compound treatment 0.284 0.0466 0.67 0.282 0.0515 0.86 1.0824 0.9918 1140174 ChemDiv3_011663 CC1CCc2cc(F)ccc2N1C(=O)Nc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C04 compound treatment 0.294 0.0566 0.81 0.275 0.0445 0.75 1.1005 0.9992 3035202 ChemDiv3_011664 CC1=C(C)CC(C(C1)C(=O)O)C(=O)Nc2ccc(c(C)c2)n3cnnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C05 compound treatment 0.265 0.0276 0.4 0.14 -0.0905 -1.52 -0.795 -0.5064 3035204 ChemDiv3_011665 CS/C(=N\c1cc(n[nH]1)c2ccccc2)/Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C06 compound treatment 0.049 -0.188 -2.69 0.253 0.0225 0.38 -1.6386 -0.6023 3035205 ChemDiv3_011666 O=C(Nc1noc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C07 compound treatment 0.258 0.0206 0.3 0.063 -0.168 -2.81 -1.7797 -0.6295 3122438 ChemDiv3_011667 Cc1ccc(cc1)n2c(=O)c(C#N)cc3c(=O)n4ccccc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C08 compound treatment 0.23 -0.00737 -0.11 0.273 0.0425 0.71 0.4294 0.596 3035207 ChemDiv3_011668 CCSc1ncc(Cl)c(n1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CC(C)OC(C)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C09 compound treatment 0.247 0.00962 0.14 0.283 0.0525 0.88 0.7201 0.8078 3122439 ChemDiv3_011669 CCCCC(O)(C(CN1CCOCC1)c2ccccc2)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C10 compound treatment 0.278 0.0406 0.58 0.271 0.0405 0.68 0.8912 0.997 3122440 ChemDiv3_011670 CCN1C(=O)C2(N(CCO)C(=O)c3oc4ccccc4c(=O)c32)c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C11 compound treatment 0.288 0.0506 0.72 0.216 -0.0145 -0.24 0.3396 0.4444 3035209 ChemDiv3_011671 CN(C)C(CNS(=O)(=O)c1ccc(C)cc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C12 compound treatment 0.268 0.0306 0.44 0.303 0.0725 1.22 1.1698 0.9049 3122441 ChemDiv3_011672 O=C(/C=C/c1ccco1)N(Cc2ccccc2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C13 compound treatment 0.243 0.00562 0.08 0.265 0.0345 0.58 0.466 0.7978 3035211 ChemDiv3_011673 Cn1c2ccccc2c3nnc(SCCCC(=O)c4ccc(F)cc4)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C14 compound treatment 0.245 0.00762 0.11 0.27 0.0395 0.66 0.5455 0.8126 3122442 ChemDiv3_011674 O=C(NCCCc1nc2ccccc2[nH]1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C15 compound treatment 0.269 0.0316 0.45 0.194 -0.0365 -0.61 -0.1137 -0.1492 3122443 ChemDiv3_011675 CCCCC(=O)Oc1cc(c2ccccc2)c3oc(=O)sc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C16 compound treatment 0.252 0.0146 0.21 0.303 0.0725 1.22 1.008 0.8167 3035213 ChemDiv3_011676 Oc1nc(Cc2ccc(F)cc2)nc3n(CSCC(=O)Nc4ccc(F)cc4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C17 compound treatment 0.241 0.00362 0.05 0.241 0.0105 0.18 0.1609 0.8783 3122444 ChemDiv3_011677 Cn1c(nc2n(C)c(=O)n(C)c(=O)c12)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C18 compound treatment 0.221 -0.0164 -0.23 0.243 0.0125 0.21 -0.0176 -0.0562 3035215 ChemDiv3_011678 FC(F)(F)Oc1ccc(NC2CCNCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C19 compound treatment 0.241 0.00362 0.05 0.255 0.0245 0.41 0.3271 0.7901 1461568 ChemDiv3_011679 COc1ccc(cc1)c2nc(NCCc3c[nH]c4cc(OC)ccc34)sc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C20 compound treatment 0.266 0.0286 0.41 0.251 0.0205 0.34 0.5324 0.9962 3122445 ChemDiv3_011680 CCOC(=O)N1CCN(Cc2cc(=O)oc3ccc(OC)cc23)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C21 compound treatment 0.245 0.00762 0.11 0.27 0.0395 0.66 0.5455 0.8126 3035217 ChemDiv3_011681 CS(=O)(=O)N(Cc1cc2ccccc2nc1O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C22 compound treatment 0.287 0.0496 0.71 0.264 0.0335 0.56 0.8991 0.9933 3122446 ChemDiv3_011682 COC(CNC(=O)c1oc2ccc3OC(C)(C)C=Cc3c2c1C)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C23 mock treatment 0.266 0.0286 0.41 0.23 -5.31E-4 -0.01 0.2832 0.6915 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 C24 mock treatment 0.226 -0.0114 -0.16 0.24 0.00947 0.16 -0.0027 -0.0118 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D01 compound treatment 0.212 -0.0254 -0.36 0.237 0.00647 0.11 -0.1799 -0.4748 3035219 ChemDiv3_011683 CC1CCCC(Nc2c([nH]c3c(C#N)cnn23)c4ccc(Cl)cc4)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D02 compound treatment 0.258 0.0206 0.3 0.289 0.0585 0.98 0.9025 0.8807 3122447 ChemDiv3_011684 O=C(CCCn1sc2ccccc2c1=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D03 compound treatment 0.268 0.0306 0.44 0.322 0.0915 1.54 1.3953 0.874 3122448 ChemDiv3_011685 CC(C(=O)N(C)Cc1ccccc1)n2c3ccccc3c4nc(=O)cc(C)n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D04 compound treatment 0.286 0.0486 0.7 0.335 0.104 1.75 1.7316 0.918 3035221 ChemDiv3_011686 Clc1cccc(c1)c2nc(nc-3c2COc4ccccc43)N5CCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D05 compound treatment 0.328 0.0906 1.3 0.298 0.0675 1.13 1.7173 0.9977 3122449 ChemDiv3_011687 Fc1ccc(cc1)N2CCN(CC2)C(=O)CSCc3cnn(c3n4cccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D06 compound treatment 0.327 0.0896 1.28 0.295 0.0645 1.08 1.6716 0.9964 3035223 ChemDiv3_011688 Cc1cccc(NC(=O)CCC2=NS(=O)(=O)c3cc(Br)cnc3N2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D07 compound treatment 0.275 0.0376 0.54 0.257 0.0265 0.44 0.6947 0.9955 3122450 ChemDiv3_011689 CCOC(=O)N1CCC(CC1)NC(=O)c2oc3CCc4cn[nH]c4-c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D08 compound treatment 0.297 0.0596 0.85 0.307 0.0765 1.28 1.5106 0.9803 3035257 ChemDiv3_011690 CCOC(=O)c1cc(cn1C)S(=O)(=O)Nc2cccc(c2)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D09 compound treatment 0.307 0.0696 1.0 0.314 0.0835 1.4 1.6948 0.986 3035258 ChemDiv3_011691 CC1=C(c2ccc(C)cc2)S(=O)(=O)N=C1Nc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D10 compound treatment 0.3 0.0626 0.9 0.304 0.0735 1.23 1.5053 0.9877 3035260 ChemDiv3_011692 Nc1ncc(Br)cc1S(=O)(=O)NCCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D11 compound treatment 0.323 0.0856 1.22 0.289 0.0585 0.98 1.5599 0.994 3035261 ChemDiv3_011693 CC1CN(C(=O)CCC(=O)N2CCC(CC2)C(=O)N)c3ccccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D12 compound treatment 0.351 0.114 1.63 0.314 0.0835 1.4 2.1398 0.9973 3035262 ChemDiv3_011694 O=c1n(Cc2ccccc2)c3nnc(c4ccsc4)n3c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D13 compound treatment 0.218 -0.0194 -0.28 0.182 -0.0485 -0.81 -0.7719 -0.8972 3035264 ChemDiv3_011695 Clc1ccc(Sc2c([nH]c3ccccc23)C(=O)N4CCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D14 compound treatment 0.309 0.0716 1.02 0.282 0.0515 0.86 1.3353 0.9964 3035265 ChemDiv3_011696 O=C(N1CCC2(CC1)OCCO2)c3noc-4c3COc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D15 compound treatment 0.256 0.0186 0.27 0.249 0.0185 0.31 0.4076 0.9972 3122451 ChemDiv3_011697 COc1ccc2c(Sc3ccccc3)c([nH]c2c1)C(=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D16 compound treatment 0.271 0.0336 0.48 0.312 0.0815 1.37 1.307 0.9017 3035267 ChemDiv3_011698 CN(CCC#N)C(=O)c1nn(C)c-2c1COc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D17 compound treatment 0.301 0.0636 0.91 0.339 0.108 1.82 1.9308 0.9487 3122452 ChemDiv3_011699 Cc1nn(CC(=O)NCc2ccc3OCOc3c2)c(=O)c4c5ccccc5sc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D18 compound treatment 0.302 0.0646 0.92 0.271 0.0405 0.68 1.1339 0.9885 3122453 ChemDiv3_011700 CCOc1ccc(CC(=O)NCc2cn3ccc(C)cc3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D19 compound treatment 0.309 0.0716 1.02 0.32 0.0895 1.5 1.7863 0.9826 3035269 ChemDiv3_011701 CCc1ccc(NC(=O)Cn2ncn3cccc3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D20 compound treatment 0.297 0.0596 0.85 0.315 0.0845 1.42 1.6055 0.9704 3122454 ChemDiv3_011702 Cc1ccn2cc(CCNC(=O)CC(C)(C)C)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D21 compound treatment 0.343 0.106 1.51 0.322 0.0915 1.54 2.1539 1.0 3035272 ChemDiv3_011703 CC(C(=O)NC1CCCC1)n2sc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D22 compound treatment 0.329 0.0916 1.31 0.267 0.0365 0.61 1.3595 0.9399 3122455 ChemDiv3_011704 Cc1ccn2cc(CNS(=O)(=O)c3ccc(Cl)s3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D23 mock treatment 0.275 0.0376 0.54 0.227 -0.00353 -0.06 0.3386 0.6255 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 D24 mock treatment 0.274 0.0366 0.52 0.245 0.0145 0.24 0.5422 0.9389 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E01 compound treatment 0.262 0.0246 0.35 0.25 0.0195 0.33 0.4801 0.9993 3122456 ChemDiv3_011705 CC1CCCN(C1)c2ccc3nc4ccccc4c(=O)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E02 compound treatment 0.251 0.0136 0.19 0.277 0.0465 0.78 0.6893 0.8574 3035274 ChemDiv3_011706 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)N2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E03 compound treatment 0.282 0.0446 0.64 0.249 0.0185 0.31 0.6705 0.945 3122641 ChemDiv3_011707 CC1CN(CCN1c2cccc(C)c2)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E04 compound treatment 0.296 0.0586 0.84 0.295 0.0645 1.08 1.3581 0.9921 3035276 ChemDiv3_011708 CC(C)c1ccc(NC(=O)NN2CCOCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E05 compound treatment 0.305 0.0676 0.97 0.27 0.0395 0.66 1.1524 0.983 3122642 ChemDiv3_011709 CS/C(=N\c1cc(n[nH]1)c2ccccc2)/NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E06 compound treatment 0.333 0.0956 1.37 0.323 0.0925 1.55 2.0646 0.998 3035278 ChemDiv3_011710 CC(C)(C)C(=O)Nc1noc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E07 compound treatment 0.316 0.0786 1.12 0.276 0.0455 0.76 1.3349 0.9822 3122643 ChemDiv3_011711 COCCn1c(=O)c(C#N)cc2c(=O)n3ccccc3nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E08 compound treatment 0.27 0.0326 0.47 0.268 0.0375 0.63 0.7747 0.9892 3122644 ChemDiv3_011712 COc1ccc(cc1)C2C3C4CCC(C4)C3Sc5[nH]c(=S)sc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E09 compound treatment 0.29 0.0526 0.75 0.302 0.0715 1.2 1.3805 0.9748 3035280 ChemDiv3_011713 CCc1ccc(cc1)C(O)(C(CN2CCOCC2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E10 compound treatment 0.302 0.0646 0.92 0.319 0.0885 1.48 1.7036 0.974 3122645 ChemDiv3_011714 CC1(C)CC(=O)C(CO1)C2(O)C(=O)N(CN3CCOCC3)c4ccccc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E11 compound treatment 0.265 0.0276 0.4 0.276 0.0455 0.76 0.819 0.9531 1251385 ChemDiv3_011715 CN(C)C1CCCCC1NS(=O)(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E12 compound treatment 0.285 0.0476 0.68 0.317 0.0865 1.45 1.5079 0.9406 3122646 ChemDiv3_011716 COC(=O)C1CN(C(=O)COc2ccccc2)c3ccccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E13 compound treatment 0.287 0.0496 0.71 0.302 0.0715 1.2 1.3501 0.9686 3122647 ChemDiv3_011717 Fc1ccc(cc1)C(=O)CCCSc2nnc3c4ccccc4n(CC=C)c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E14 compound treatment 0.332 0.0946 1.35 0.317 0.0865 1.45 1.9833 0.9994 3035283 ChemDiv3_011718 O=C(NCCCc1nc2ccccc2n1CCCOc3ccccc3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E15 compound treatment 0.322 0.0846 1.21 0.254 0.0235 0.39 1.1344 0.8912 3122648 ChemDiv3_011719 COc1ccc(cc1)c2cc(OC(=O)c3ccccc3)cc4sc(=O)oc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E16 compound treatment 0.269 0.0316 0.45 0.302 0.0715 1.2 1.1681 0.9111 3035324 ChemDiv3_011720 CS(=O)CCNC(=O)Nc1ccc(Cl)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E17 compound treatment 0.24 0.00262 0.04 0.277 0.0465 0.78 0.578 0.7403 3035326 ChemDiv3_011721 CCC(Sc1nnc2c3ccccc3n(CC=C)c2n1)C(=O)Nc4nnc(s4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E18 compound treatment 0.338 0.101 1.44 0.289 0.0585 0.98 1.7117 0.9826 3035327 ChemDiv3_011722 Cn1nnc2c(NCC(=O)C(C)(C)C)nc(Cc3ccc(Cl)cc3Cl)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E19 compound treatment 0.281 0.0436 0.62 0.305 0.0745 1.25 1.325 0.9485 3035329 ChemDiv3_011723 COc1cccc(c1)c2noc(n2)c3ccc(Br)o3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E20 compound treatment 0.285 0.0476 0.68 0.282 0.0515 0.86 1.0925 0.9931 3035330 ChemDiv3_011724 CC(C)/C=C(/C(=O)c1ccc(Cl)cc1Cl)\n2cncn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E21 compound treatment 0.279 0.0416 0.6 0.241 0.0105 0.18 0.5452 0.8783 3035332 ChemDiv3_011725 CN(Cc1cc2ccccc2nc1O)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E22 compound treatment 0.287 0.0496 0.71 0.253 0.0225 0.38 0.7686 0.9562 3035333 ChemDiv3_011726 CCN(c1nnc(NC(=O)Nc2ccc(CC)cc2)s1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E23 mock treatment 0.259 0.0216 0.31 0.224 -0.00653 -0.11 0.1412 0.4303 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 E24 mock treatment 0.244 0.00662 0.09 0.256 0.0255 0.43 0.3693 0.8434 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F01 compound treatment 0.252 0.0146 0.21 0.269 0.0385 0.65 0.6045 0.8906 3122649 ChemDiv3_011727 CCC1N(CCn2c(C)ccc12)C(=O)NC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F02 compound treatment 0.279 0.0416 0.6 0.287 0.0565 0.95 1.0912 0.9749 3035336 ChemDiv3_011728 CCc1ccccc1NC(=O)CCCn2sc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F03 compound treatment 0.251 0.0136 0.19 0.276 0.0455 0.76 0.6774 0.8601 3122650 ChemDiv3_011729 CNC(=O)C(C)n1c2ccccc2c3nc(=O)cc(C)n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F04 compound treatment 0.29 0.0526 0.75 0.24 0.00947 0.16 0.6446 0.8379 3122651 ChemDiv3_011730 NC(=O)C1CCN(CC1)c2nc(c3cccc(Cl)c3)c4COc5ccccc5-c4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F05 compound treatment 0.324 0.0866 1.24 0.319 0.0885 1.48 1.9261 0.996 3035338 ChemDiv3_011731 Brc1ccccc1NC(=O)CSCc2cnn(c2n3cccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F06 compound treatment 0.279 0.0416 0.6 0.297 0.0665 1.12 1.2099 0.9568 3035340 ChemDiv3_011732 COC(=O)c1cc(cn1C)S(=O)(=O)N(C)C2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F07 compound treatment 0.311 0.0736 1.05 0.29 0.0595 1.0 1.4504 0.9996 3122652 ChemDiv3_011733 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)Nc4cc(C)cc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F08 compound treatment 0.364 0.127 1.81 0.334 0.103 1.74 2.5087 0.9998 3122653 ChemDiv3_011734 CCOC(=O)c1cc(cn1C)S(=O)(=O)N(CC)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F09 compound treatment 0.312 0.0746 1.07 0.301 0.0705 1.18 1.5911 0.9987 3035342 ChemDiv3_011735 CC(NC1=NS(=O)(=O)C(=C1C)c2ccc(C)cc2)C3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F10 compound treatment 0.346 0.109 1.55 0.368 0.137 2.31 2.7301 0.9815 3122654 ChemDiv3_011736 CC1Cc2ccccc2N1S(=O)(=O)c3cc(Br)cnc3N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F11 compound treatment 0.328 0.0906 1.3 0.331 0.1 1.69 2.109 0.9916 3122655 ChemDiv3_011737 CC1CN(C(=O)CCC(=O)NCc2ccco2)c3ccccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F12 compound treatment 0.314 0.0766 1.1 0.359 0.128 2.16 2.2997 0.9508 3035346 ChemDiv3_011738 CC(=O)Nc1ccc(cc1)c2nnc3n(Cc4ccccc4Cl)c(=O)c5ccccc5n23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F13 compound treatment 0.229 -0.00837 -0.12 0.166 -0.0645 -1.08 -0.8506 -0.7806 3122656 ChemDiv3_011739 CCCCN(C)C(=O)c1[nH]c2ccccc2c1Sc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F14 compound treatment 0.376 0.139 1.98 0.253 0.0225 0.38 1.6687 0.8268 3122657 ChemDiv3_011740 CN(C(=O)c1noc-2c1COc3ccccc23)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F15 compound treatment 0.298 0.0606 0.87 0.302 0.0715 1.2 1.4614 0.9873 3035348 ChemDiv3_011741 COc1ccc2c(Sc3ccccc3)c([nH]c2c1)C(=O)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F16 compound treatment 0.327 0.0896 1.28 0.31 0.0795 1.33 1.8496 0.9998 3122658 ChemDiv3_011742 Cn1nc(C(=O)N2CCCN(Cc3ccccc3Cl)C2)c4COc5ccccc5-c41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F17 compound treatment 0.364 0.127 1.81 0.379 0.148 2.49 3.0428 0.9877 3035350 ChemDiv3_011743 CCCNC(=O)Cn1nc(C)c2sc3ccccc3c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F18 compound treatment 0.304 0.0666 0.95 0.299 0.0685 1.15 1.4865 0.9957 3122659 ChemDiv3_011744 COc1ccc(CCC(=O)NCc2cn3ccc(C)cc3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F19 compound treatment 0.321 0.0836 1.2 0.314 0.0835 1.4 1.8364 0.9969 3035352 ChemDiv3_011745 CC(C(=O)NCc1cccs1)n2ncn3cccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F20 compound treatment 0.319 0.0816 1.17 0.311 0.0805 1.35 1.7806 0.9974 3035393 ChemDiv3_011746 Cc1ccn2cc(CCNC(=O)C3CCCCC3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F21 compound treatment 0.299 0.0616 0.88 0.294 0.0635 1.07 1.3765 0.9956 3035395 ChemDiv3_011747 CC(C(=O)Nc1cc(C)ccc1C)n2sc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F22 compound treatment 0.303 0.0656 0.94 0.266 0.0355 0.6 1.0847 0.9759 3035397 ChemDiv3_011748 CN(C)S(=O)(=O)NCc1cn2ccc(C)cc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F23 mock treatment 0.296 0.0586 0.84 0.264 0.0335 0.56 0.9902 0.981 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 F24 mock treatment 0.213 -0.0244 -0.35 0.237 0.00647 0.11 -0.1698 -0.4649 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G01 compound treatment 0.252 0.0146 0.21 0.249 0.0185 0.31 0.3671 0.9817 3035398 ChemDiv3_011749 O=C(NC1CCCCC1)N2CCCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G02 compound treatment 0.241 0.00362 0.05 0.276 0.0455 0.76 0.5763 0.7534 3035399 ChemDiv3_011750 CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)n3cnnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G03 compound treatment 0.129 -0.108 -1.55 0.159 -0.0715 -1.2 -1.9451 -0.992 3035401 ChemDiv3_011751 Cc1[nH]c2c(c(nn2c(=O)c1Cc3ccccc3)C(F)(F)F)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G04 compound treatment 0.292 0.0546 0.78 0.292 0.0615 1.03 1.282 0.9906 3035402 ChemDiv3_011752 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)Nc2ccc(cc2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G05 compound treatment 0.292 0.0546 0.78 0.315 0.0845 1.42 1.555 0.9606 3035404 ChemDiv3_011753 Cc1ccc(CSc2nnc(s2)n3c(=O)c(C#N)cc4c(=O)n5ccccc5nc34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G06 compound treatment 0.282 0.0446 0.64 0.297 0.0665 1.12 1.2402 0.9649 3122660 ChemDiv3_011754 CCCCC1CCC(CC1)C(=O)N(Cc2sccc2C)C3CCS(=O)(=O)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G07 compound treatment 0.296 0.0586 0.84 0.316 0.0855 1.43 1.6073 0.9673 3035406 ChemDiv3_011755 CC(C)Cn1c(=O)c(C#N)cc2c(=O)n3ccccc3nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G08 compound treatment 0.341 0.104 1.48 0.319 0.0885 1.48 2.098 1.0 3122661 ChemDiv3_011756 CCC(Sc1nc2ccccc2o1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G09 compound treatment 0.271 0.0336 0.48 0.293 0.0625 1.05 1.0815 0.9375 3122662 ChemDiv3_011757 Cc1ccc(cc1)C2=NN=C(NC(=O)CSc3ccccc3)SC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G10 compound treatment 0.295 0.0576 0.82 0.342 0.111 1.87 1.9058 0.9322 3035409 ChemDiv3_011758 O=C(CCc1nc(no1)c2ccccc2)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G11 compound treatment 0.31 0.0726 1.04 0.299 0.0685 1.15 1.5471 0.9987 1594495 ChemDiv3_011759 Cc1ccc(NC2CCCCC2NS(=O)(=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G12 compound treatment 0.269 0.0316 0.45 0.329 0.0985 1.65 1.4885 0.8687 3035411 ChemDiv3_011760 COC(=O)C1CN(C(=O)/C=C/c2ccccc2)c3ccccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G13 compound treatment 0.3 0.0626 0.9 0.305 0.0745 1.25 1.5172 0.9867 3122663 ChemDiv3_011761 CC(C)n1c2ccccc2c3nnc(SCCCC(=O)c4ccc(F)cc4)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G14 compound treatment 0.253 0.0156 0.22 0.153 -0.0775 -1.3 -0.7621 -0.5772 3122664 ChemDiv3_011762 Cc1ccc(Nc2nc(SCc3ccccc3)nnc2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G15 compound treatment 0.306 0.0686 0.98 0.313 0.0825 1.38 1.6728 0.9858 3035413 ChemDiv3_011763 Cc1cc(C)c2c(CC(=O)Oc3ccc(Cl)cc3)coc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G16 compound treatment 0.295 0.0576 0.82 0.313 0.0825 1.38 1.5616 0.9693 3122665 ChemDiv3_011764 CC(C)c1ccc(NC(=O)NCCS(=O)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G17 compound treatment 0.332 0.0946 1.35 0.286 0.0555 0.93 1.6154 0.9833 1302345 ChemDiv3_011765 O=C(CSC(=S)N1CCOCC1)c2c[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G18 compound treatment 0.29 0.0526 0.75 0.302 0.0715 1.2 1.3805 0.9748 3122666 ChemDiv3_011766 O=C1CC(=Nc2ncccc2N1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G19 compound treatment 0.306 0.0686 0.98 0.303 0.0725 1.22 1.5542 0.9943 3035417 ChemDiv3_011767 FC(F)(F)c1ccc(cc1)c2noc(n2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G20 compound treatment 0.311 0.0736 1.05 0.285 0.0545 0.91 1.3911 0.9975 3122667 ChemDiv3_011768 O=C(Nc1cccs1)Nc2ccccc2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G21 compound treatment 0.299 0.0616 0.88 0.288 0.0575 0.96 1.3053 0.999 3035418 ChemDiv3_011769 Cc1[nH]c2nc(nn2c(=O)c1C)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G22 compound treatment 0.258 0.0206 0.3 0.159 -0.0715 -1.2 -0.6403 -0.5179 3122668 ChemDiv3_011770 CCc1ccc(cc1)c2[nH]c3c(C#N)cnn3c2NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G23 mock treatment 0.243 0.00562 0.08 0.224 -0.00653 -0.11 -0.0206 -0.1516 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 G24 mock treatment 0.208 -0.0294 -0.42 0.197 -0.0335 -0.56 -0.6951 -0.9896 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H01 compound treatment 0.27 0.0326 0.47 0.276 0.0455 0.76 0.8696 0.9721 3122669 ChemDiv3_011771 Cc1cccc2n(ncc12)C(=O)Nc3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H02 compound treatment 0.242 0.00462 0.07 0.263 0.0325 0.54 0.4321 0.7872 3035467 ChemDiv3_011772 Cc1ccccc1NC(=O)CCCn2sc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H03 compound treatment 0.251 0.0136 0.19 0.268 0.0375 0.63 0.5825 0.8847 3035469 ChemDiv3_011773 CC(C(=O)Nc1c(F)c(F)cc(F)c1F)n2c3ccccc3c4nc(=O)cc(C)n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H04 compound treatment 0.253 0.0156 0.22 0.239 0.00847 0.14 0.2585 0.9761 3035471 ChemDiv3_011774 COc1ccc(OC)c(Nc2nc(c3cccc(Cl)c3)c4COc5ccccc5-c4n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H05 compound treatment 0.303 0.0656 0.94 0.353 0.122 2.06 2.1172 0.9369 3035472 ChemDiv3_011775 CC(C)NC(=O)CSCc1cnn(c1n2cccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H06 compound treatment 0.3 0.0626 0.9 0.319 0.0885 1.48 1.6834 0.9707 3035473 ChemDiv3_011776 COC(=O)c1cc(cn1C)S(=O)(=O)NCCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H07 compound treatment 0.243 0.00562 0.08 0.276 0.0455 0.76 0.5965 0.7773 3035475 ChemDiv3_011777 COc1ccc(cc1)C2SCC(N2C(=O)Nc3ccc(C)c(C)c3)C(=O)NC4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H08 compound treatment 0.332 0.0946 1.35 0.308 0.0775 1.3 1.8765 0.9998 3122848 ChemDiv3_011778 CCOC(=O)c1cc(cn1C)S(=O)(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H09 compound treatment 0.262 0.0246 0.35 0.339 0.108 1.82 1.5364 0.8285 3122849 ChemDiv3_011779 COc1ccc(OC)c(CCNC2=NS(=O)(=O)C(=C2C)c3ccc(C)cc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H10 compound treatment 0.276 0.0386 0.55 0.24 0.00947 0.16 0.503 0.875 3035477 ChemDiv3_011780 Cc1cc(F)ccc1NS(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H11 compound treatment 0.319 0.0816 1.17 0.292 0.0615 1.03 1.5551 0.9981 3122850 ChemDiv3_011781 CCc1cccc(C)c1NC(=O)CCC(=O)N2CCOc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H12 compound treatment 0.322 0.0846 1.21 0.336 0.105 1.77 2.1076 0.9828 3035479 ChemDiv3_011782 O=c1n(CCc2ccccc2)c3nnc(c4ccccc4)n3c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H13 compound treatment 0.321 0.0836 1.2 0.307 0.0765 1.28 1.7533 0.9994 3122851 ChemDiv3_011783 CCCNC(=O)c1[nH]c2ccccc2c1Sc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H14 compound treatment 0.301 0.0636 0.91 0.304 0.0735 1.23 1.5155 0.9888 3035482 ChemDiv3_011784 CN(C(=O)c1noc-2c1CSc3ccccc23)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H15 compound treatment 0.284 0.0466 0.67 0.33 0.0995 1.67 1.6521 0.919 3122852 ChemDiv3_011785 CCCNC(=O)c1[nH]c2cc(OC)ccc2c1Sc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H16 compound treatment 0.342 0.105 1.5 0.316 0.0855 1.43 2.0726 0.9998 3122853 ChemDiv3_011786 Cn1nc(C(=O)NCCN(Cc2ccco2)C3CCCC3)c4COc5ccccc5-c41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H17 compound treatment 0.294 0.0566 0.81 0.293 0.0625 1.05 1.3141 0.9919 3035484 ChemDiv3_011787 CC(C(=O)N(C)Cc1ccccc1)n2nc(C)c3sc4ccccc4c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H18 compound treatment 0.267 0.0296 0.42 0.275 0.0445 0.75 0.8274 0.964 3122854 ChemDiv3_011788 Cc1cccn2cc(CNC(=O)c3ccccc3)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H19 compound treatment 0.303 0.0656 0.94 0.286 0.0555 0.93 1.3221 1.0 3035486 ChemDiv3_011789 O=C(Cn1sc2ccccc2c1=O)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H20 compound treatment 0.314 0.0766 1.1 0.256 0.0255 0.43 1.0773 0.9157 3122855 ChemDiv3_011790 Cc1ccn2cc(CCNC(=O)c3ccc(cc3)C(F)(F)F)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H21 compound treatment 0.283 0.0456 0.65 0.281 0.0505 0.85 1.0604 0.9917 3122856 ChemDiv3_011791 CC(C(=O)Nc1ccc(Br)c(C)c1)n2sc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H22 compound treatment 0.299 0.0616 0.88 0.217 -0.0135 -0.23 0.4627 0.5083 3035489 ChemDiv3_011792 Cc1cccn2cc(CNS(=O)(=O)c3cccc(F)c3)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H23 mock treatment 0.219 -0.0184 -0.26 0.235 0.00447 0.08 -0.1328 -0.4859 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 H24 mock treatment 0.237 -3.75E-4 -0.01 0.208 -0.0225 -0.38 -0.2712 -0.7171 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I01 compound treatment 0.249 0.0116 0.17 0.253 0.0225 0.38 0.3842 0.9323 3122857 ChemDiv3_011793 Cc1cccc(C)c1NC(=O)NC2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I02 compound treatment 0.249 0.0116 0.17 0.269 0.0385 0.65 0.5741 0.8611 3035491 ChemDiv3_011794 COc1cc(ccc1n2cnnn2)S(=O)(=O)N3CCCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I03 compound treatment 0.282 0.0446 0.64 0.304 0.0735 1.23 1.3233 0.953 3122858 ChemDiv3_011795 COc1ccc(cc1)c2c(C)nn3c(=O)c(Cc4ccccc4)c(C)[nH]c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I04 compound treatment 0.293 0.0556 0.8 0.294 0.0635 1.07 1.3159 0.9897 3035493 ChemDiv3_011796 Cn1ncc2c3nc(nn3cnc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I05 compound treatment 0.31 0.0726 1.04 0.265 0.0345 0.58 1.1436 0.9618 3122859 ChemDiv3_011797 FC(F)(F)c1cccc(c1)n2c(=O)c(C#N)cc3c(=O)n4ccccc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I06 compound treatment 0.302 0.0646 0.92 0.282 0.0515 0.86 1.2645 0.9994 3034374 ChemDiv3_011798 Cc1ccc(CN(C2CCS(=O)(=O)C2)C(=O)COc3c(F)c(F)c(F)c(F)c3F)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I07 compound treatment 0.27 0.0326 0.47 0.308 0.0775 1.3 1.2494 0.9044 3034376 ChemDiv3_011799 CCCCn1c(=O)c(C#N)cc2c(=O)n3ccccc3nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I08 compound treatment 0.304 0.0666 0.95 0.275 0.0445 0.75 1.2016 0.9927 3034377 ChemDiv3_011800 CC(C)Cc1nc2ccccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I09 compound treatment 0.271 0.0336 0.48 0.249 0.0185 0.31 0.5593 0.9774 3034379 ChemDiv3_011801 Cc1ccc(cc1)C2=NN=C(NC(=O)C(F)(F)F)SC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I10 compound treatment 0.297 0.0596 0.85 0.294 0.0635 1.07 1.3563 0.9939 3034380 ChemDiv3_011802 CC(=O)N1C2=C(CCCC2)C(=O)NC31CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I11 compound treatment 0.325 0.0876 1.25 0.295 0.0645 1.08 1.6514 0.9973 3034381 ChemDiv3_011803 COc1ccccc1NC2CCCCC2NS(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I12 compound treatment 0.273 0.0356 0.51 0.269 0.0385 0.65 0.8169 0.9931 3034383 ChemDiv3_011804 COc1cccc(CN(C2CCS(=O)(=O)C2)C(=O)/C=C/c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I13 compound treatment 0.286 0.0486 0.7 0.283 0.0525 0.88 1.1145 0.9932 3122860 ChemDiv3_011805 Cn1c2ccccc2c3nnc(SCCCC(=O)c4ccc5OCCOc5c4)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I14 compound treatment 0.294 0.0566 0.81 0.274 0.0435 0.73 1.0886 0.9986 1510276 ChemDiv3_011806 OC(=O)CC(NC(=O)C(c1ccccc1)c2ccccc2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I15 compound treatment 0.306 0.0686 0.98 0.287 0.0565 0.95 1.3643 0.9998 3034385 ChemDiv3_011807 CCc1nnc(NC(=O)Cc2coc3ccc(C)cc23)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I16 compound treatment 0.271 0.0336 0.48 0.138 -0.0925 -1.55 -0.7581 -0.4663 3122861 ChemDiv3_011808 Fc1ccc(NC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I17 compound treatment 0.325 0.0876 1.25 0.256 0.0255 0.43 1.1885 0.8975 1374294 ChemDiv3_011809 O=C(c1c[nH]c2ccccc12)c3sc(nc3c4ccccc4)N5CCOCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I18 compound treatment 0.265 0.0276 0.4 0.241 0.0105 0.18 0.4036 0.9334 3122862 ChemDiv3_011810 O=C(COc1nsnc1N2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I19 compound treatment 0.298 0.0606 0.87 0.262 0.0315 0.53 0.9866 0.9717 3122863 ChemDiv3_011811 CCCCN(Cc1cc2cccc(C)c2nc1O)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I20 compound treatment 0.236 -0.00138 -0.02 0.278 0.0475 0.8 0.5495 0.6894 3034389 ChemDiv3_011812 Cc1cc(NC(=O)Nc2cccs2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I21 compound treatment 0.226 -0.0114 -0.16 0.254 0.0235 0.39 0.1635 0.3836 3034391 ChemDiv3_011813 Cc1[nH]c2nc(Cc3ccccc3)nn2c(=O)c1Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I22 compound treatment 0.257 0.0196 0.28 0.236 0.00547 0.09 0.2634 0.8919 3122864 ChemDiv3_011814 CC1CCC(CC1)Nc2c([nH]c3c(C#N)cnn23)c4cccc(Br)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I23 mock treatment 0.252 0.0146 0.21 0.225 -0.00553 -0.09 0.0823 0.3595 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 I24 mock treatment 0.232 -0.00537 -0.08 0.23 -5.31E-4 -0.01 -0.0607 -0.7839 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J01 compound treatment 0.231 -0.00637 -0.09 0.24 0.00947 0.16 0.0479 0.2614 3122865 ChemDiv3_011815 CNC(=O)c1oc2ccc3OC4(CCCCC4)CC(=O)c3c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J02 compound treatment 0.255 0.0176 0.25 0.265 0.0345 0.58 0.5873 0.9307 3034393 ChemDiv3_011816 O=C(CCCn1sc2ccccc2c1=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J03 compound treatment 0.257 0.0196 0.28 0.287 0.0565 0.95 0.8687 0.8788 3122866 ChemDiv3_011817 CCC(C(=O)NC1CCCC1)n2c3ccccc3c4nc(=O)cc(C)n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J04 compound treatment 0.301 0.0636 0.91 0.264 0.0335 0.56 1.0407 0.9731 3034395 ChemDiv3_011818 CCN1CCN(CC1)c2nc(c3cccc(Cl)c3)c4COc5ccccc5-c4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J05 compound treatment 0.303 0.0656 0.94 0.282 0.0515 0.86 1.2746 0.9991 3122867 ChemDiv3_011819 CC1CCCC(NC(=O)CSCc2cnn(c2n3cccc3)c4ccccc4)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J06 compound treatment 0.278 0.0406 0.58 0.318 0.0875 1.47 1.449 0.9177 3122868 ChemDiv3_011820 COC(=O)c1cc(cn1C)S(=O)(=O)N2CCN(CC2)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J07 compound treatment 0.305 0.0676 0.97 0.313 0.0825 1.38 1.6627 0.9846 3034397 ChemDiv3_011821 COc1ccc(cc1)C2SCC(N2C(=O)Nc3ccc(C)c(C)c3)C(=O)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J08 compound treatment 0.279 0.0416 0.6 0.3 0.0695 1.17 1.2455 0.9513 3122869 ChemDiv3_011822 CCOC(=O)c1cc(cn1C)S(=O)(=O)NCC2CCCO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J09 compound treatment 0.278 0.0406 0.58 0.259 0.0285 0.48 0.7488 0.9953 3122870 ChemDiv3_011823 CN(Cc1ccccc1)C(=O)c2sc3nc(C)cc(C)c3c2n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J10 compound treatment 0.342 0.105 1.5 0.258 0.0275 0.46 1.3842 0.8839 3034400 ChemDiv3_011824 CN(c1ccc(C)cc1)S(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J11 compound treatment 0.298 0.0606 0.87 0.27 0.0395 0.66 1.0816 0.9912 3122871 ChemDiv3_011825 CCOc1ccc(CCNC(=O)Cn2ncn3nc(cc3c2=O)c4cccs4)cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J12 compound treatment 0.336 0.0986 1.41 0.287 0.0565 0.95 1.6677 0.9813 3034456 ChemDiv3_011826 CN(CC(=O)NCc1ccccn1)S(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J13 compound treatment 0.297 0.0596 0.85 0.282 0.0515 0.86 1.2139 1.0 3034458 ChemDiv3_011827 Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(=O)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J14 compound treatment 0.327 0.0896 1.28 0.313 0.0825 1.38 1.8852 0.9993 3034460 ChemDiv3_011828 CCC(C)NC(=O)c1nn(C)c-2c1COc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J15 compound treatment 0.323 0.0856 1.22 0.284 0.0535 0.9 1.5006 0.9883 3034461 ChemDiv3_011829 COc1ccc2c(Sc3ccc(C)cc3)c([nH]c2c1)C(=O)NCCc4ccc(OC)c(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J16 compound treatment 0.289 0.0516 0.74 0.276 0.0455 0.76 1.0618 0.9999 3034463 ChemDiv3_011830 Cc1c(sc2nc3SCC(=Nn3c(=O)c12)c4cc(O)ccc4O)C(=O)Nc5ccccc5Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J17 compound treatment 0.307 0.0696 1.0 0.273 0.0425 0.71 1.2082 0.9866 3034465 ChemDiv3_011831 CNC(=O)C(C)n1nc(C)c2sc3ccccc3c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J18 compound treatment 0.324 0.0866 1.24 0.35 0.119 2.01 2.294 0.9732 3122872 ChemDiv3_011832 Cc1cccn2cc(CNC(=O)C(C)(C)C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J19 compound treatment 0.288 0.0506 0.72 0.306 0.0755 1.27 1.4077 0.9648 3034466 ChemDiv3_011833 O=C(Cn1sc2ccccc2c1=O)N3CCN(CC3)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J20 compound treatment 0.291 0.0536 0.77 0.29 0.0595 1.0 1.2482 0.9915 3122873 ChemDiv3_011834 CCOc1ccccc1C(=O)NCCc2cn3ccc(C)cc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J21 compound treatment 0.29 0.0526 0.75 0.284 0.0535 0.9 1.1668 0.9962 3034468 ChemDiv3_011835 CNC(=O)C(C)n1sc2ccccc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J22 compound treatment 0.228 -0.00937 -0.13 0.246 0.0155 0.26 0.0888 0.3038 3122874 ChemDiv3_011836 CCc1ccc(s1)S(=O)(=O)NCCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J23 mock treatment 0.244 0.00662 0.09 0.245 0.0145 0.24 0.2387 0.9158 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 J24 mock treatment 0.21 -0.0274 -0.39 0.245 0.0145 0.24 -0.1052 -0.2282 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K01 compound treatment 0.275 0.0376 0.54 0.276 0.0455 0.76 0.9202 0.9854 3122875 ChemDiv3_011837 CC1CCCC(C)N1NC(=O)Nc2c(C)cccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K02 compound treatment 0.254 0.0166 0.24 0.263 0.0325 0.54 0.5535 0.9309 3034471 ChemDiv3_011838 CN(C)S(=O)(=O)c1ccc(cc1)S(=O)(=O)N2CCC3(CC2)OCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K03 compound treatment 0.245 0.00762 0.11 0.268 0.0375 0.63 0.5218 0.8175 3123052 ChemDiv3_011839 COc1ccc(cc1)c2c(C)nn3c(N)c(cnc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K04 compound treatment 0.321 0.0836 1.2 0.291 0.0605 1.01 1.5635 0.9967 3034473 ChemDiv3_011840 Cn1ncc2c3nc(Cc4ccccc4)nn3cnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K05 compound treatment 0.286 0.0486 0.7 0.251 0.0205 0.34 0.7347 0.9471 3123053 ChemDiv3_011841 COc1ccc(cc1Cl)n2c(=O)c(C#N)cc3c(=O)n4ccccc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K06 compound treatment 0.285 0.0476 0.68 0.291 0.0605 1.01 1.1993 0.9812 3034475 ChemDiv3_011842 O=C(N(Cc1ccco1)C2CCS(=O)(=O)C2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K07 compound treatment 0.252 0.0146 0.21 0.214 -0.0165 -0.28 -0.0483 -0.1389 3123054 ChemDiv3_011843 COc1ccc(Cn2nnc3c(O)nc(nc23)C4CCCN(C4)S(=O)(=O)c5ccccc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K08 compound treatment 0.302 0.0646 0.92 0.214 -0.0165 -0.28 0.4574 0.474 1708292 ChemDiv3_011844 CC(C)OC(=O)C(C)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K09 compound treatment 0.245 0.00762 0.11 0.262 0.0315 0.53 0.4506 0.8355 3034478 ChemDiv3_011845 NC(=O)C(Cc1ccccc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K10 compound treatment 0.303 0.0656 0.94 0.26 0.0295 0.49 1.0135 0.9552 3123055 ChemDiv3_011846 O=C(N1C2=C(CCCC2)C(=O)NC31CCCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K11 compound treatment 0.33 0.0926 1.32 0.286 0.0555 0.93 1.5951 0.9851 3123056 ChemDiv3_011847 Brc1ccccc1NC2CCCCC2NS(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K12 compound treatment 0.27 0.0326 0.47 0.253 0.0225 0.38 0.5966 0.9944 3034480 ChemDiv3_011848 COc1ccc(cc1)c2n(cc3n(C)c(=O)n(C)c(=O)c23)c4cccc(NC(=O)C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K13 compound treatment 0.28 0.0426 0.61 0.261 0.0305 0.51 0.7927 0.9962 3123057 ChemDiv3_011849 CCCn1c2ccccc2c3nnc(SCCCC(=O)c4ccc5OCCOc5c4)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K14 compound treatment 0.262 0.0246 0.35 0.292 0.0615 1.03 0.9786 0.8976 3034482 ChemDiv3_011850 OC(=O)CC(NC(=O)C(c1ccccc1)c2ccccc2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K15 compound treatment 0.291 0.0536 0.77 0.266 0.0355 0.6 0.9633 0.9921 3123058 ChemDiv3_011851 CCc1ccc2occ(CC(=O)Nc3sc4CCCCc4c3C(=O)OC)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K16 compound treatment 0.274 0.0366 0.52 0.264 0.0335 0.56 0.7676 0.9994 3034538 ChemDiv3_011852 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K17 compound treatment 0.276 0.0386 0.55 0.292 0.0615 1.03 1.1202 0.9572 1478592 ChemDiv3_011853 O=C(CSC(=S)N1CCOCC1)Nc2nc(cs2)c3c[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K18 compound treatment 0.273 0.0356 0.51 0.26 0.0295 0.49 0.7101 0.9999 3034540 ChemDiv3_011854 Oc1nsnc1N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K19 compound treatment 0.304 0.0666 0.95 0.265 0.0345 0.58 1.0829 0.9714 3034541 ChemDiv3_011855 CCCCn1nc(NS(=O)(=O)c2ccc(C)cc2)c3cc4cccc(C)c4nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K20 compound treatment 0.242 0.00462 0.07 0.286 0.0555 0.93 0.7051 0.7554 3034543 ChemDiv3_011856 Cc1nn(CC(=O)NC2CCCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K21 compound treatment 0.264 0.0266 0.38 0.227 -0.00353 -0.06 0.2274 0.59 3034544 ChemDiv3_011857 CCCc1cc(=O)n2ncnc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K22 compound treatment 0.259 0.0216 0.31 0.274 0.0435 0.73 0.7346 0.927 3034546 ChemDiv3_011858 N#Cc1cnn2c(NC3CCCC3)c([nH]c12)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K23 mock treatment 0.21 -0.0274 -0.39 0.251 0.0205 0.34 -0.034 -0.0652 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 K24 mock treatment 0.252 0.0146 0.21 0.201 -0.0295 -0.5 -0.2026 -0.3765 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L01 compound treatment 0.235 -0.00238 -0.03 0.265 0.0345 0.58 0.3851 0.6644 3123059 ChemDiv3_011859 COc1cc(OC)c(NC(=O)c2oc3ccc4OC5(CCCC5)CC(=O)c4c3c2C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L02 compound treatment 0.264 0.0266 0.38 0.302 0.0715 1.2 1.1175 0.8879 3034548 ChemDiv3_011860 O=C(CCCn1sc2ccccc2c1=O)NC3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L03 compound treatment 0.254 0.0166 0.24 0.299 0.0685 1.15 0.9807 0.8357 3123060 ChemDiv3_011861 CCC(C(=O)Nc1ccccc1CC)n2c3ccccc3c4nc(=O)cc(C)n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L04 compound treatment 0.257 0.0196 0.28 0.272 0.0415 0.7 0.6906 0.9203 3034550 ChemDiv3_011862 Clc1cccc(c1)c2nc(NCCCN3CCCC3=O)nc-4c2COc5ccccc54 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L05 compound treatment 0.267 0.0296 0.42 0.249 0.0185 0.31 0.5188 0.9882 3123061 ChemDiv3_011863 CNC(=O)CSCc1cnn(c1n2cccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L06 compound treatment 0.327 0.0896 1.28 0.249 0.0185 0.31 1.1257 0.8535 3123062 ChemDiv3_011864 COC(=O)c1cc(cn1C)S(=O)(=O)N2C(C)Cc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L07 compound treatment 0.3 0.0626 0.9 0.276 0.0455 0.76 1.173 0.9968 3123063 ChemDiv3_011865 COc1ccccc1NC(=O)N2C(CSC2c3ccccc3C)C(=O)NCc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L08 compound treatment 0.313 0.0756 1.08 0.227 -0.00353 -0.06 0.723 0.6674 3034553 ChemDiv3_011866 COc1ccc(NS(=O)(=O)c2cc(Br)cnc2N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L09 compound treatment 0.27 0.0326 0.47 0.212 -0.0185 -0.31 0.11 0.1962 3034555 ChemDiv3_011867 CC1CCN(CC1)C(=O)c2sc3nc(C)cc(C)c3c2n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L10 compound treatment 0.325 0.0876 1.25 0.292 0.0615 1.03 1.6158 0.9953 3123064 ChemDiv3_011868 CCN(CC)S(=O)(=O)c1cc(Br)cnc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L11 compound treatment 0.287 0.0496 0.71 0.222 -0.00853 -0.14 0.4007 0.5533 3123065 ChemDiv3_011869 O=C(Cn1ncn2nc(cc2c1=O)c3ccco3)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L12 compound treatment 0.317 0.0796 1.14 0.314 0.0835 1.4 1.796 0.9947 3034558 ChemDiv3_011870 CN(CC(=O)NC1CCCC1)S(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L13 compound treatment 0.268 0.0306 0.44 0.293 0.0625 1.05 1.0511 0.925 3123066 ChemDiv3_011871 Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(=O)NCCN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L14 compound treatment 0.268 0.0306 0.44 0.323 0.0925 1.55 1.4072 0.8726 3034559 ChemDiv3_011872 COc1ccccc1CNC(=O)c2nn(C)c-3c2COc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L15 compound treatment 0.264 0.0266 0.38 0.25 0.0195 0.33 0.5003 0.9971 3123067 ChemDiv3_011873 COc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(=O)N(C)Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L16 compound treatment 0.283 0.0456 0.65 0.293 0.0625 1.05 1.2028 0.974 3034561 ChemDiv3_011874 O=C(NCc1cn2ccccc2n1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L17 compound treatment 0.293 0.0556 0.8 0.331 0.1 1.69 1.755 0.9412 3123068 ChemDiv3_011875 CCC(C(=O)N1CCCC1)n2nc(C)c3sc4ccccc4c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L18 compound treatment 0.312 0.0746 1.07 0.298 0.0675 1.13 1.5555 0.9996 3123069 ChemDiv3_011876 Cc1cccn2cc(CNC(=O)CC3CCCC3)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L19 compound treatment 0.27 0.0326 0.47 0.297 0.0665 1.12 1.1188 0.9252 3034563 ChemDiv3_011877 O=C(Cn1sc2ccccc2c1=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L20 compound treatment 0.253 0.0156 0.22 0.312 0.0815 1.37 1.1249 0.8119 3123070 ChemDiv3_011878 Cc1cccn2cc(CCNC(=O)CC3CCCCC3)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L21 compound treatment 0.301 0.0636 0.91 0.206 -0.0245 -0.41 0.3524 0.3528 3034564 ChemDiv3_011879 CCC(C(=O)N1CCN(CC1)c2cc(C)ccc2C)n3sc4ccccc4c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L22 compound treatment 0.299 0.0616 0.88 0.216 -0.0145 -0.24 0.4508 0.4929 3034624 ChemDiv3_011880 O=S(=O)(NCCc1cn2ccccc2n1)c3ccc4CCCCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L23 mock treatment 0.218 -0.0194 -0.28 0.236 0.00547 0.09 -0.1311 -0.4489 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 L24 mock treatment 0.234 -0.00337 -0.05 0.214 -0.0165 -0.28 -0.2303 -0.8178 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M01 compound treatment 0.284 0.0466 0.67 0.255 0.0245 0.41 0.762 0.9729 3034626 ChemDiv3_011881 CCOc1ccc(NC(=O)NN2C(C)CCCC2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M02 compound treatment 0.289 0.0516 0.74 0.269 0.0385 0.65 0.9787 0.9978 3034627 ChemDiv3_011882 COc1cc(ccc1n2cnnn2)S(=O)(=O)NCCc3c[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M03 compound treatment 0.286 0.0486 0.7 0.306 0.0755 1.27 1.3875 0.9602 3034628 ChemDiv3_011883 COc1cccc2c1oc(=O)c3c(NC(=O)C)nc4CCCCCc4c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M04 compound treatment 0.261 0.0236 0.34 0.267 0.0365 0.61 0.6718 0.9608 3034630 ChemDiv3_011884 Cc1cccc(C)c1OCc2nc3c4cnn(C)c4ncn3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M05 compound treatment 0.281 0.0436 0.62 0.242 0.0115 0.19 0.5773 0.8841 3034631 ChemDiv3_011885 O=c1c(C#N)cc2c(=O)n3ccccc3nc2n1CCN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M06 compound treatment 0.222 -0.0154 -0.22 0.221 -0.00953 -0.16 -0.2686 -0.9878 1320773 ChemDiv3_011886 Cn1c(=O)[nH]c2nnc(nc2c1=O)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M07 compound treatment 0.301 0.0636 0.91 0.295 0.0645 1.08 1.4086 0.9963 3123071 ChemDiv3_011887 CCN(CC)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)S(=O)(=O)c3ncccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M08 compound treatment 0.27 0.0326 0.47 0.254 0.0235 0.39 0.6085 0.9964 3034634 ChemDiv3_011888 Cc1cc(OCC(=O)N(Cc2ccco2)Cc3ccc(Cl)cc3)cc(C)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M09 compound treatment 0.279 0.0416 0.6 0.269 0.0385 0.65 0.8776 0.9992 3123072 ChemDiv3_011889 CN(C)C(=O)C(Cc1ccccc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M10 compound treatment 0.324 0.0866 1.24 0.242 0.0115 0.19 1.0123 0.8073 3034636 ChemDiv3_011890 Clc1ccc(cc1)c2nn3c(nnc3c4ccccc24)c5ccco5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M11 compound treatment 0.279 0.0416 0.6 0.241 0.0105 0.18 0.5452 0.8783 3123073 ChemDiv3_011891 CC(C)(C)NC1CCCCC1NS(=O)(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M12 compound treatment 0.304 0.0666 0.95 0.279 0.0485 0.81 1.2491 0.9969 3034638 ChemDiv3_011892 Cn1c(=O)n(C)c2cn(c(c3ccc(cc3)C(C)(C)C)c2c1=O)c4cc(N)c(Cl)cc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M13 compound treatment 0.289 0.0516 0.74 0.27 0.0395 0.66 0.9906 0.9985 3123074 ChemDiv3_011893 Cc1nnc(SCCCC(=O)c2ccc(cc2)C(C)(C)C)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M14 compound treatment 0.298 0.0606 0.87 0.272 0.0415 0.7 1.1053 0.9941 3123075 ChemDiv3_011894 OC(=O)CC(NC(=O)Cc1ccc(Cl)cc1)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M15 compound treatment 0.272 0.0346 0.5 0.22 -0.0105 -0.18 0.2252 0.4283 3034641 ChemDiv3_011895 Cc1cc(C)c2c(CC(=O)Nc3c(oc4ccccc34)C(=O)c5ccccc5)coc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M16 compound treatment 0.291 0.0536 0.77 0.256 0.0255 0.43 0.8446 0.9619 3123076 ChemDiv3_011896 COc1ccc(cc1)c2ccc(Nc3ccc(OC(F)(F)F)cc3)nn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M17 compound treatment 0.284 0.0466 0.67 0.288 0.0575 0.96 1.1536 0.9838 3123077 ChemDiv3_011897 Oc1cc(nc(SCC(=O)c2c[nH]c3ccccc23)n1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M18 compound treatment 0.288 0.0506 0.72 0.261 0.0305 0.51 0.8736 0.9855 3034643 ChemDiv3_011898 Nc1nnc(CC(=O)N2CCCCC2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M19 compound treatment 0.29 0.0526 0.75 0.255 0.0245 0.41 0.8227 0.9594 3123078 ChemDiv3_011899 Cc1ccc2nc(O)c(CN(C3CCCCC3)S(=O)(=O)c4ccccc4)cc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M20 compound treatment 0.253 0.0156 0.22 0.257 0.0265 0.44 0.4722 0.9495 3034645 ChemDiv3_011900 CC1CCCCN1c2nnc(NC(=O)Nc3cccc(C)c3C)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M21 compound treatment 0.25 0.0126 0.18 0.241 0.0105 0.18 0.2519 0.9999 3123258 ChemDiv3_011901 CC1(O)Cc2[nH]nc(O)c2C(C1C(=O)OCC=C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M22 compound treatment 0.261 0.0236 0.34 0.217 -0.0135 -0.23 0.0784 0.1925 3034647 ChemDiv3_011902 CC1CCCC(NC(=O)CCCC(=O)n2ncc3cc(C)ccc23)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M23 mock treatment 0.209 -0.0284 -0.41 0.204 -0.0265 -0.45 -0.6019 -0.9989 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 M24 mock treatment 0.211 -0.0264 -0.38 0.213 -0.0175 -0.29 -0.4748 -0.9924 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N01 compound treatment 0.234 -0.00337 -0.05 0.247 0.0165 0.28 0.1613 0.5749 3123259 ChemDiv3_011903 COc1cccc(NC(=O)Cn2c3ccccc3c4nc(=O)cc(C)n24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N02 compound treatment 0.126 -0.111 -1.59 0.209 -0.0215 -0.36 -1.382 -0.846 3123260 ChemDiv3_011904 O=C(CCCn1sc2ccccc2c1=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N03 compound treatment 0.264 0.0266 0.38 0.295 0.0645 1.08 1.0344 0.9018 3034649 ChemDiv3_011905 CCC(C(=O)NC(C)C)n1c2ccccc2c3nc(=O)cc(C)n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N04 compound treatment 0.265 0.0276 0.4 0.288 0.0575 0.96 0.9614 0.9224 3123261 ChemDiv3_011906 CN1C(=CC(=NS1(=O)=O)c2ccc(C)cc2)C(=O)Nc3sc4CCCCc4c3C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N05 compound treatment 0.258 0.0206 0.3 0.253 0.0225 0.38 0.4753 0.9926 3034570 ChemDiv3_011907 O=C(NCc1ccccc1)C2CCN(Cc3cnn(c3n4cccc4)c5ccccc5)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N06 compound treatment 0.323 0.0856 1.22 0.299 0.0685 1.15 1.6786 0.9995 3034572 ChemDiv3_011908 COC(=O)c1cc(cn1C)S(=O)(=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N07 compound treatment 0.284 0.0466 0.67 0.27 0.0395 0.66 0.94 1.0 3034573 ChemDiv3_011909 CC1=C(c2ccc(C)cc2)S(=O)(=O)N=C1N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N08 compound treatment 0.266 0.0286 0.41 0.291 0.0605 1.01 1.0072 0.9203 3034576 ChemDiv3_011910 CN(Cc1ccccc1)S(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N09 compound treatment 0.258 0.0206 0.3 0.288 0.0575 0.96 0.8907 0.883 3034577 ChemDiv3_011911 CNC(=O)c1sc2nc(C)cc(C)c2c1n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N10 compound treatment 0.326 0.0886 1.27 0.305 0.0745 1.25 1.7802 1.0 3034579 ChemDiv3_011912 CCCN(c1ccccc1OC)S(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N11 compound treatment 0.291 0.0536 0.77 0.282 0.0515 0.86 1.1532 0.9982 3034581 ChemDiv3_011913 CCNC(=O)C1CCCN(C1)c2nnc(s2)N3CCCC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N12 compound treatment 0.315 0.0776 1.11 0.356 0.125 2.11 2.2742 0.9553 3123262 ChemDiv3_011914 CCc1ccc(NC(=O)CN(C)S(=O)(=O)c2cc(Br)cnc2N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N13 compound treatment 0.287 0.0496 0.71 0.236 0.00547 0.09 0.5668 0.7919 3123263 ChemDiv3_011915 CC(NC(=O)c1[nH]c2cc(C)ccc2c1Sc3ccc(Cl)cc3)c4ccc5OCCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N14 compound treatment 0.284 0.0466 0.67 0.219 -0.0115 -0.19 0.3347 0.482 3034586 ChemDiv3_011916 COc1ccc(C)cc1N(C)C(=O)c2nn(C)c-3c2COc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N15 compound treatment 0.289 0.0516 0.74 0.296 0.0655 1.1 1.2991 0.9813 3123264 ChemDiv3_011917 CCN1CCCC1CNC(=O)c2[nH]c3cc(OC)ccc3c2Sc4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N16 compound treatment 0.329 0.0916 1.31 0.305 0.0745 1.25 1.8105 0.9997 3034588 ChemDiv3_011918 FC(F)(F)c1cccc(c1)C(=O)NCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N17 compound treatment 0.262 0.0246 0.35 0.264 0.0335 0.56 0.6463 0.9747 3034652 ChemDiv3_011919 CCC(C(=O)Nc1cccc(C)c1C)n2nc(C)c3sc4ccccc4c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N18 compound treatment 0.302 0.0646 0.92 0.248 0.0175 0.29 0.861 0.8878 3034655 ChemDiv3_011920 FC(F)(F)c1cccc(c1)C(=O)NCCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N19 compound treatment 0.304 0.0666 0.95 0.267 0.0365 0.61 1.1067 0.9771 3034656 ChemDiv3_011921 CC(C(=O)N1CCCCCC1)n2sc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N20 compound treatment 0.24 0.00262 0.04 0.247 0.0165 0.28 0.222 0.7958 3034659 ChemDiv3_011922 COc1ccc(cc1F)S(=O)(=O)NCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N21 compound treatment 0.279 0.0416 0.6 0.257 0.0265 0.44 0.7351 0.9896 3034662 ChemDiv3_011923 CCC(C(=O)NCc1cccc(OC)c1OC)n2sc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N22 compound treatment 0.241 0.00362 0.05 0.273 0.0425 0.71 0.5407 0.7565 3034664 ChemDiv3_011924 Cc1ccn2cc(CCNS(=O)(=O)c3ccc(Cl)s3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N23 mock treatment 0.224 -0.0134 -0.19 0.227 -0.00353 -0.06 -0.1772 -0.8847 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 N24 mock treatment 0.215 -0.0224 -0.32 0.236 0.00547 0.09 -0.1614 -0.4848 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O01 compound treatment 0.286 0.0486 0.7 0.256 0.0255 0.43 0.7941 0.9727 1616600 ChemDiv3_011925 O=C(NCCc1c[nH]c2ccccc12)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O02 compound treatment 0.283 0.0456 0.65 0.262 0.0315 0.53 0.8349 0.9945 3123265 ChemDiv3_011926 OC(=O)COCC(=O)Nc1ccc2c(c1)oc3ccccc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O03 compound treatment 0.198 -0.0394 -0.56 0.234 0.00347 0.06 -0.3571 -0.6307 3123266 ChemDiv3_011927 CS/C(=N\c1cc(n[nH]1)c2ccccc2)/NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O04 compound treatment 0.235 -0.00238 -0.03 0.259 0.0285 0.48 0.3138 0.6552 3034668 ChemDiv3_011928 Cc1ccc(cc1)n2ncc3c4nc(Cc5ccccc5)nn4cnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O05 compound treatment 0.272 0.0346 0.5 0.27 0.0395 0.66 0.8186 0.9897 3123267 ChemDiv3_011929 O=c1c(C#N)cc2c(=O)n3ccccc3nc2n1CCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O06 compound treatment 0.261 0.0236 0.34 0.262 0.0315 0.53 0.6124 0.9767 3123268 ChemDiv3_011930 CSc1ncc(Cl)c(n1)C(=O)Nc2c(oc3ccccc23)C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O07 compound treatment 0.254 0.0166 0.24 0.28 0.0495 0.83 0.7552 0.8745 3034673 ChemDiv3_011931 OC(CCN1CCOCC1)(C2CCCCC2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O08 compound treatment 0.248 0.0106 0.15 0.287 0.0565 0.95 0.7776 0.8101 3123269 ChemDiv3_011932 CCCN1C(=O)C2(N(CCOC)C(=O)c3oc4ccccc4c(=O)c32)c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O09 compound treatment 0.273 0.0356 0.51 0.25 0.0195 0.33 0.5914 0.9769 3034851 ChemDiv3_011933 O=C(Nc1ccccc1)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O10 compound treatment 0.219 -0.0184 -0.26 0.248 0.0175 0.29 0.0215 0.0545 3034852 ChemDiv3_011934 Oc1ccccc1c2n[nH]c3C(=O)N(Cc4ccco4)C(c23)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O11 compound treatment 0.268 0.0306 0.44 0.259 0.0285 0.48 0.6476 0.9991 3034917 ChemDiv3_011935 O=S(=O)(NC1CCCCC1NC2CCCCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O12 compound treatment 0.26 0.0226 0.32 0.177 -0.0535 -0.9 -0.4065 -0.4256 3034919 ChemDiv3_011936 CC(=C)n1c(=O)n(Cc2ccc(C)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O13 compound treatment 0.253 0.0156 0.22 0.243 0.0125 0.21 0.306 0.9995 3034920 ChemDiv3_011937 Cc1cc2nsnc2c(c1C)S(=O)(=O)N3CCN=C3Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O14 compound treatment 0.252 0.0146 0.21 0.249 0.0185 0.31 0.3671 0.9817 3034923 ChemDiv3_011938 CC(NC(=O)C(O)(c1ccccc1)c2ccccc2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O15 compound treatment 0.245 0.00762 0.11 0.245 0.0145 0.24 0.2488 0.9347 3034925 ChemDiv3_011939 CCc1ccc(NC(=O)Cc2coc3ccc(cc23)C(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O16 compound treatment 0.243 0.00562 0.08 0.264 0.0335 0.56 0.4541 0.8002 3034926 ChemDiv3_011940 O=C(N1CCN(CC1)c2ncnc3[nH]cnc23)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O17 compound treatment 0.258 0.0206 0.3 0.246 0.0155 0.26 0.3922 0.998 3034927 ChemDiv3_011941 CC1=C(SC2=NCCN12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O18 compound treatment 0.263 0.0256 0.37 0.268 0.0375 0.63 0.7039 0.967 3034928 ChemDiv3_011942 CC1CCCCC1NS(=O)(=O)c2ccc(cc2)S(=O)(=O)N3CCN(CC3)c4ncccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O19 compound treatment 0.279 0.0416 0.6 0.257 0.0265 0.44 0.7351 0.9896 3123270 ChemDiv3_011943 CCCn1nc(NC(=O)c2cccc(Cl)c2)c3cc4cc(C)ccc4nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O20 compound treatment 0.236 -0.00138 -0.02 0.249 0.0185 0.31 0.2053 0.6609 3123271 ChemDiv3_011944 CC1CCCC(C)N1c2nnc(NC(=O)Nc3ccc(C)c(C)c3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O21 compound treatment 0.252 0.0146 0.21 0.214 -0.0165 -0.28 -0.0483 -0.1389 1359944 ChemDiv3_011945 COc1ccc(cc1OC)S(=O)(=O)N2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O22 compound treatment 0.242 0.00462 0.07 0.213 -0.0175 -0.29 -0.1613 -0.5348 3123272 ChemDiv3_011946 CCc1ccc(cc1)c2[nH]c3c(C#N)cnn3c2NCCC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O23 mock treatment 0.21 -0.0274 -0.39 0.2 -0.0305 -0.51 -0.6392 -0.9912 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 O24 mock treatment 0.233 -0.00437 -0.06 0.216 -0.0145 -0.24 -0.2167 -0.8607 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P01 compound treatment 0.274 0.0366 0.52 0.256 0.0255 0.43 0.6727 0.9949 3034934 ChemDiv3_011947 COc1ccc(CNC(=O)Cn2c3ccccc3c4nc(=O)cc(C)n24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P02 compound treatment 0.275 0.0376 0.54 0.29 0.0595 1.0 1.0863 0.958 3123273 ChemDiv3_011948 CN1CCC(=CC1)c2noc(CCC(=O)Nc3ccc(F)cc3F)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P03 compound treatment 0.245 0.00762 0.11 0.271 0.0405 0.68 0.5574 0.8103 3123274 ChemDiv3_011949 COc1cc2n(CC(=O)NC3CCCC(C)C3C)n4c(C)cc(=O)nc4c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P04 compound treatment 0.292 0.0546 0.78 0.265 0.0345 0.58 0.9616 0.9891 3034938 ChemDiv3_011950 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P05 compound treatment 0.253 0.0156 0.22 0.262 0.0315 0.53 0.5315 0.9268 3123275 ChemDiv3_011951 CCc1cccc(NC(=O)C2CCN(Cc3cnn(c3n4cccc4)c5ccccc5)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P06 compound treatment 0.245 0.00762 0.11 0.242 0.0115 0.19 0.2132 0.9638 3123276 ChemDiv3_011952 CCOC(=O)c1cc(cn1C)S(=O)(=O)N(C)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P07 compound treatment 0.254 0.0166 0.24 0.278 0.0475 0.8 0.7315 0.8798 3035307 ChemDiv3_011953 CC1=C(c2ccc(C)cc2)S(=O)(=O)N=C1NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P08 compound treatment 0.244 0.00662 0.09 0.253 0.0225 0.38 0.3337 0.8581 3123277 ChemDiv3_011954 CC1CCN(CC1)S(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P09 compound treatment 0.262 0.0246 0.35 0.236 0.00547 0.09 0.314 0.8626 3123278 ChemDiv3_011955 Cc1cc(C)c2c(c(sc2n1)C(=O)NCCCN3CCN(CC3)c4ccc(F)cc4)n5cccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P10 compound treatment 0.259 0.0216 0.31 0.234 0.00347 0.06 0.2599 0.8257 3035310 ChemDiv3_011956 COc1ccc(OC)c(c1)N(C)S(=O)(=O)c2cc(Br)cnc2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P11 compound treatment 0.162 -0.0754 -1.08 0.142 -0.0885 -1.49 -1.8131 -0.9876 3123279 ChemDiv3_011957 Cc1ccc(Sc2c([nH]c3ccccc23)C(=O)NCc4ccco4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P12 compound treatment 0.282 0.0446 0.64 0.256 0.0255 0.43 0.7536 0.981 3035313 ChemDiv3_011958 CN(Cc1ccccc1)C(=O)c2noc-3c2COc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P13 compound treatment 0.258 0.0206 0.3 0.259 0.0285 0.48 0.5465 0.9731 3123280 ChemDiv3_011959 COc1cccc(CNC(=O)c2[nH]c3cc(C)ccc3c2Sc4ccc(Cl)cc4)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P14 compound treatment 0.252 0.0146 0.21 0.28 0.0495 0.83 0.735 0.8584 3035317 ChemDiv3_011960 Cn1nc(C(=O)N2CCN(CC2)c3cccc(c3)C(F)(F)F)c4COc5ccccc5-c41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P15 compound treatment 0.253 0.0156 0.22 0.295 0.0645 1.08 0.9232 0.8355 3123281 ChemDiv3_011961 COc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(=O)NCCCN4CCN(C)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P16 compound treatment 0.226 -0.0114 -0.16 0.24 0.00947 0.16 -0.0027 -0.0118 3035318 ChemDiv3_011962 CCOc1ccccc1C(=O)NCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P17 compound treatment 0.272 0.0346 0.5 0.271 0.0405 0.68 0.8305 0.988 3123282 ChemDiv3_011963 Cc1nn(CCCC(=O)N2CCCC2)c(=O)c3c4ccccc4sc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P18 compound treatment 0.252 0.0146 0.21 0.241 0.0105 0.18 0.2722 0.9962 3123283 ChemDiv3_011964 COc1ccc(CCC(=O)NCCc2cn3ccccc3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P19 compound treatment 0.272 0.0346 0.5 0.274 0.0435 0.73 0.8661 0.9822 3123284 ChemDiv3_011965 COc1ccc(NC(=O)C(C)n2sc3ccccc3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P20 compound treatment 0.256 0.0186 0.27 0.258 0.0275 0.46 0.5144 0.966 3120228 ChemDiv3_011966 CCc1ccc(s1)S(=O)(=O)NCc2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P21 compound treatment 0.272 0.0346 0.5 0.248 0.0175 0.29 0.5575 0.9687 3035373 ChemDiv3_011967 O=C(CCCn1sc2ccccc2c1=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P22 compound treatment 0.228 -0.00937 -0.13 0.239 0.00847 0.14 0.0057 0.0291 3120229 ChemDiv3_011968 Cc1cccn2cc(CCNS(=O)(=O)c3ccc(Oc4ccccc4)cc3)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P23 mock treatment 0.213 -0.0244 -0.35 0.222 -0.00853 -0.14 -0.3478 -0.9227 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2034 P24 mock treatment 0.209 -0.0284 -0.41 0.211 -0.0195 -0.33 -0.5188 -0.9944 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A01 compound treatment 0.223 -0.00522 -0.07 0.259 0.0399 0.67 0.4208 0.6244 3035375 ChemDiv3_011969 CCn1c(=O)cc([nH]c1=O)N2CCC(C)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A02 compound treatment 0.23 0.00178 0.03 0.248 0.0289 0.49 0.3611 0.7432 3120230 ChemDiv3_011970 COc1ccc(cc1)N2CCN(CCNC(=O)c3nnc(o3)c4ccc5OCOc5c4)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A03 compound treatment 0.231 0.00278 0.04 0.228 0.00891 0.15 0.1338 0.8652 3035380 ChemDiv3_011971 O=C(Nc1ccc(cc1)c2nc3cccnc3s2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A04 compound treatment 0.243 0.0148 0.21 0.258 0.0389 0.65 0.6112 0.8905 3120231 ChemDiv3_011972 CCOC(=O)N1CCC(CC1)NC(=O)c2sc3nc4CCCCn4c(=O)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A05 compound treatment 0.236 0.00778 0.11 0.248 0.0289 0.49 0.4218 0.8473 3120232 ChemDiv3_011973 O=C(NCC(N1CCN(CC1)c2ccccc2)c3cccnc3)OCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A06 compound treatment 0.256 0.0278 0.4 0.258 0.0389 0.65 0.7427 0.9716 3035384 ChemDiv3_011974 COC(=O)c1ccc(NC(=O)N2CCOc3ccc(C)cc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A07 compound treatment 0.248 0.0198 0.28 0.236 0.0169 0.28 0.4007 1.0 3120233 ChemDiv3_011975 CCOc1ccc(NC(=O)c2cc([nH]c2C)c3ccc(F)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A08 compound treatment 0.227 -0.00122 -0.02 0.258 0.0389 0.65 0.4494 0.688 3035387 ChemDiv3_011976 CCN1CCCC1CNC(=O)c2ccc(cc2)n3c(cc4CCCCc43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A09 compound treatment 0.229 7.81E-4 0.01 0.237 0.0179 0.3 0.2204 0.7329 3120234 ChemDiv3_011977 Cc1cc(NC(=O)CSc2nc3nccnc3c(=O)n2Cc4ccccc4)[nH]n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A10 compound treatment 0.246 0.0178 0.25 0.262 0.0429 0.72 0.6891 0.9022 3120235 ChemDiv3_011978 Cc1ccc(CSc2nc3ccc(cc3n2C)C(=O)NCCN4CCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A11 compound treatment 0.255 0.0268 0.38 0.246 0.0269 0.45 0.5902 0.9966 3035440 ChemDiv3_011979 CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A12 compound treatment 0.254 0.0258 0.37 0.216 -0.00309 -0.05 0.224 0.6016 3120236 ChemDiv3_011980 O=C(Cn1c(=O)c2cccn2c3ccccc13)NC4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A13 compound treatment 0.242 0.0138 0.2 0.226 0.00691 0.12 0.2214 0.968 3035442 ChemDiv3_011981 CN(C)C(=O)c1cc2c(=O)n3ccccc3nc2n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A14 compound treatment 0.217 -0.0112 -0.16 0.237 0.0179 0.3 0.099 0.2907 3120237 ChemDiv3_011982 O=C(NC1CCCC1)C2CCN(CC2)c3nc4ccccc4n5cccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A15 compound treatment 0.248 0.0198 0.28 0.243 0.0239 0.4 0.4838 0.9854 3120238 ChemDiv3_011983 CCN(C(=O)c1cc(cn1C)S(=O)(=O)N2CCc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A16 compound treatment 0.27 0.0418 0.6 0.231 0.0119 0.2 0.5639 0.8948 3035447 ChemDiv3_011984 CCn1cc2CCc3oc(C(=O)N4CCc5ccccc5C4)c(C)c3-c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A17 compound treatment 0.281 0.0528 0.75 0.252 0.0329 0.55 0.9244 0.9882 3120239 ChemDiv3_011985 Cc1ccc(cc1)c2nsc(SCC(=O)NCc3ccc4OCOc4c3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A18 compound treatment 0.253 0.0248 0.35 0.234 0.0149 0.25 0.4276 0.9855 3035450 ChemDiv3_011986 O=C(N1CCCC1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A19 compound treatment 0.244 0.0158 0.23 0.202 -0.0171 -0.29 -0.0433 -0.1185 3120240 ChemDiv3_011987 COc1ccc(cc1)c2nsc(SCC(=O)N3CCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A20 compound treatment 0.192 -0.0362 -0.52 0.169 -0.0501 -0.84 -0.9608 -0.9729 3120241 ChemDiv3_011988 CCNC(=O)c1ccc2c(c1)sc3nc(cn32)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A21 compound treatment 0.24 0.0118 0.17 0.227 0.00791 0.13 0.213 0.993 3035513 ChemDiv3_011989 O=C(Cc1noc2ccccc12)NCCOC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A22 compound treatment 0.22 -0.00822 -0.12 0.225 0.00591 0.1 -0.013 -0.0847 3120242 ChemDiv3_011990 Fc1ccc(cc1)c2cc(on2)C(=O)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A23 mock treatment 0.24 0.0118 0.17 0.226 0.00691 0.12 0.2011 0.9833 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 A24 mock treatment 0.223 -0.00522 -0.07 0.219 -9.38E-5 0.0 -0.0539 -0.7219 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B01 compound treatment 0.27 0.0418 0.6 0.277 0.0579 0.97 1.1098 0.9727 3120243 ChemDiv3_011991 Fc1ccc(cc1)c2cc(on2)C(=O)N3CCN(CC3)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B02 compound treatment 0.293 0.0648 0.93 0.254 0.0349 0.59 1.0695 0.9755 3035520 ChemDiv3_011992 CCC(Sc1nnc(CC)n2c3ccsc3cc12)C(=O)N4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B03 compound treatment 0.31 0.0818 1.17 0.277 0.0579 0.97 1.5144 0.9958 3120244 ChemDiv3_011993 O=C(Cn1cnc2c3ccccc3oc2c1=O)N4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B04 compound treatment 0.283 0.0548 0.78 0.286 0.0669 1.12 1.3481 0.9845 3035525 ChemDiv3_011994 Cc1cc2c(cc3c(SCC(=O)NCc4ccco4)nncn23)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B05 compound treatment 0.288 0.0598 0.86 0.287 0.0679 1.14 1.4106 0.99 3120245 ChemDiv3_011995 CC1CCN(CC1)S(=O)(=O)c2ccc3NC(=O)COc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B06 compound treatment 0.243 0.0148 0.21 0.274 0.0549 0.92 0.8011 0.8473 3120246 ChemDiv3_011996 CCc1nnc(SCC(=O)N(CC=C)c2ccccc2)c3cc4oc(C)cc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B07 compound treatment 0.252 0.0238 0.34 0.244 0.0249 0.42 0.5361 0.9948 3035530 ChemDiv3_011997 Cc1cc2NC(=O)COc2cc1S(=O)(=O)NCCN3CCN(CC3)c4ccccc4F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B08 compound treatment 0.29 0.0618 0.88 0.276 0.0569 0.96 1.3002 0.9992 3120247 ChemDiv3_011998 Cc1ccc(CS(=O)Cc2ccc(o2)C(=O)NCc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B09 compound treatment 0.287 0.0588 0.84 0.27 0.0509 0.85 1.1987 1.0 3120248 ChemDiv3_011999 O=C(CN1C(=O)CCc2ccccc12)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B10 compound treatment 0.294 0.0658 0.94 0.268 0.0489 0.82 1.2458 0.9977 3034335 ChemDiv3_012000 C(Sc1ccc2nnc(c3ccccn3)n2n1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B11 compound treatment 0.283 0.0548 0.78 0.295 0.0759 1.27 1.4549 0.9727 3120249 ChemDiv3_012001 CCCCN(C1CCN(CC1)C(=O)C)C(=O)c2cn(c3ccc(OC)cc3)c(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B12 compound treatment 0.257 0.0288 0.41 0.278 0.0589 0.99 0.9902 0.9246 3034339 ChemDiv3_012002 CCc1ccc(NC(=O)CSc2ccc(nn2)c3ccco3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B13 compound treatment 0.248 0.0198 0.28 0.229 0.00991 0.17 0.3176 0.9679 3120250 ChemDiv3_012003 CN(Cc1ccccc1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B14 compound treatment 0.256 0.0278 0.4 0.259 0.0399 0.67 0.7546 0.9689 3120251 ChemDiv3_012004 C(Sc1ccc(nn1)c2ccncc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B15 compound treatment 0.272 0.0438 0.63 0.262 0.0429 0.72 0.952 0.9976 3034343 ChemDiv3_012005 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B16 compound treatment 0.245 0.0168 0.24 0.238 0.0189 0.32 0.3941 0.9905 3120252 ChemDiv3_012006 CCSc1ccc2nnc(CCNC(=O)c3ccccc3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B17 compound treatment 0.267 0.0388 0.55 0.26 0.0409 0.69 0.8777 0.9944 3120253 ChemDiv3_012007 CCCN(C(=O)c1ccc2c(=O)n3CCCCc3nc2c1)c4ccc(Cl)c(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B18 compound treatment 0.239 0.0108 0.15 0.247 0.0279 0.47 0.4402 0.8928 3034348 ChemDiv3_012008 COc1ccc(cc1OC)c2nc(C)c(CCNS(=O)(=O)c3ccc(Cl)s3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B19 compound treatment 0.291 0.0628 0.9 0.3 0.0809 1.36 1.5952 0.9798 3120254 ChemDiv3_012009 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B20 compound treatment 0.284 0.0558 0.8 0.272 0.0529 0.89 1.1921 0.9986 3034351 ChemDiv3_012010 COc1ccc(cc1)c2noc(CC(=O)N(C)CCC#N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B21 compound treatment 0.244 0.0158 0.23 0.249 0.0299 0.5 0.5145 0.9349 3120255 ChemDiv3_012011 CN(C(=O)CSc1nncn2c3ccsc3cc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B22 compound treatment 0.285 0.0568 0.81 0.298 0.0789 1.32 1.5108 0.9724 3034420 ChemDiv3_012012 CC1CN(Cc2ccccc2)c3nc4n(C)c(=O)n(CC=C)c(=O)c4n3C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B23 mock treatment 0.287 0.0588 0.84 0.257 0.0379 0.64 1.0444 0.9905 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 B24 mock treatment 0.222 -0.00622 -0.09 0.208 -0.0111 -0.19 -0.1946 -0.9428 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C01 compound treatment 0.271 0.0428 0.61 0.273 0.0539 0.9 1.0725 0.9819 3120256 ChemDiv3_012013 CCn1c(=O)cc([nH]c1=O)N2CCN(CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C02 compound treatment 0.266 0.0378 0.54 0.247 0.0279 0.47 0.7133 0.9975 3120423 ChemDiv3_012014 Cc1ccc(NC(=O)Cn2ccn(CCc3ccc(cc3)S(=O)(=O)N)c(=O)c2=O)cc1F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C03 compound treatment 0.271 0.0428 0.61 0.073 -0.146 -2.45 -1.3012 -0.5149 3034424 ChemDiv3_012015 O=C(COc1ccccc1)Nc2cccc(c2)c3nc4cccnc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C04 compound treatment 0.238 0.00978 0.14 0.276 0.0569 0.96 0.7743 0.8021 3034426 ChemDiv3_012016 CCN(C(=O)c1cccc2C(=O)CCSc12)c3cc(Cl)ccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C05 compound treatment 0.267 0.0388 0.55 0.041 -0.178 -2.99 -1.7214 -0.5662 3120424 ChemDiv3_012017 COc1ccc(cc1)N2CCN(CC2)C(CNC(=O)Oc3ccccc3)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C06 compound treatment 0.285 0.0568 0.81 0.296 0.0769 1.29 1.487 0.9751 3120425 ChemDiv3_012018 CC1CN(C(=O)Nc2ccc(Cl)cc2)c3ccccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C07 compound treatment 0.247 0.0188 0.27 0.245 0.0259 0.43 0.4974 0.9732 3034431 ChemDiv3_012019 Cc1[nH]c(cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)N)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C08 compound treatment 0.258 0.0298 0.43 0.045 -0.174 -2.92 -1.7649 -0.5977 3120426 ChemDiv3_012020 O=C(NCCCN1CCCCC1)c2ccc(cc2)n3c(cc4CCCCc43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C09 compound treatment 0.252 0.0238 0.34 0.28 0.0609 1.02 0.9634 0.8942 3034433 ChemDiv3_012021 Clc1ccccc1Cn2c(SCC#N)nc3nccnc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C10 compound treatment 0.278 0.0498 0.71 0.079 -0.14 -2.35 -1.1591 -0.4718 3120427 ChemDiv3_012022 O=C(Cn1c(=O)c2cccn2c3ccccc13)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C11 compound treatment 0.232 0.00378 0.05 0.231 0.0119 0.2 0.1795 0.8673 3120428 ChemDiv3_012023 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C12 compound treatment 0.27 0.0418 0.6 0.258 0.0389 0.65 0.8843 0.999 3034437 ChemDiv3_012024 CCN1CCCC1CNC(=O)Cn2c(=O)c3cccn3c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C13 compound treatment 0.278 0.0498 0.71 0.211 -0.00809 -0.14 0.4074 0.5621 3034503 ChemDiv3_012025 Cn1c(cc2c(=O)n3ccccc3nc12)C(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C14 compound treatment 0.267 0.0388 0.55 0.239 0.0199 0.33 0.6285 0.9706 3120429 ChemDiv3_012026 CNC(=O)C1CCN(CC1)c2nc3ccccc3n4cccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C15 compound treatment 0.247 0.0188 0.27 0.245 0.0259 0.43 0.4974 0.9732 3120430 ChemDiv3_012027 CCCNC(=O)c1cc(cn1C)S(=O)(=O)N2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C16 compound treatment 0.249 0.0208 0.3 0.247 0.0279 0.47 0.5414 0.9759 3034507 ChemDiv3_012028 CCn1cc2CCc3oc(C(=O)NCc4cccnc4)c(C)c3-c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C17 compound treatment 0.264 0.0358 0.51 0.263 0.0439 0.74 0.883 0.9841 3120431 ChemDiv3_012029 CCOC(=O)CSc1nc(ns1)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C18 compound treatment 0.219 -0.00922 -0.13 0.218 -0.00109 -0.02 -0.1062 -0.7979 3034510 ChemDiv3_012030 O=C(N1CCCCC1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C19 compound treatment 0.23 0.00178 0.03 0.268 0.0489 0.82 0.5984 0.7287 3120432 ChemDiv3_012031 COc1ccc(cc1)c2nsc(SCC(=O)N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C20 compound treatment 0.271 0.0428 0.61 0.231 0.0119 0.2 0.574 0.8917 3120433 ChemDiv3_012032 O=C(NCCCN1CCCCC1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C21 compound treatment 0.242 0.0138 0.2 0.278 0.0589 0.99 0.8385 0.8317 3034513 ChemDiv3_012033 CCCN(C(=O)Cc1noc2ccc(C)cc12)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C22 compound treatment 0.252 0.0238 0.34 0.266 0.0469 0.79 0.7972 0.9296 3120434 ChemDiv3_012034 CC1CCCCN1C(=O)c2cc(no2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C23 mock treatment 0.24 0.0118 0.17 0.218 -0.00109 -0.02 0.1062 0.6264 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 C24 mock treatment 0.206 -0.0222 -0.32 0.229 0.00991 0.17 -0.1072 -0.2988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D01 compound treatment 0.317 0.0888 1.27 0.259 0.0399 0.67 1.3716 0.9553 3034517 ChemDiv3_012035 CC(C)(CO)NC(=O)c1cc(no1)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D02 compound treatment 0.283 0.0548 0.78 0.27 0.0509 0.85 1.1582 0.9991 3120435 ChemDiv3_012036 Cc1oc(nc1CSc2nncn3c4ccoc4cc23)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D03 compound treatment 0.326 0.0978 1.4 0.286 0.0669 1.12 1.783 0.9941 3120436 ChemDiv3_012037 O=C(Cn1cnc2c3ccccc3oc2c1=O)N4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D04 compound treatment 0.279 0.0508 0.73 0.247 0.0279 0.47 0.8448 0.9775 3034589 ChemDiv3_012038 Cc1cc2c(cc3c(SCc4ccccc4)nncn23)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D05 compound treatment 0.361 0.133 1.9 0.277 0.0579 0.97 2.0302 0.9516 3120437 ChemDiv3_012039 CCCNS(=O)(=O)c1ccc2NC(=O)COc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D06 compound treatment 0.303 0.0748 1.07 0.307 0.0879 1.48 1.7996 0.9875 3120438 ChemDiv3_012040 O=C(Cn1c(=O)c2cccn2c3cccnc13)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D07 compound treatment 0.274 0.0458 0.65 0.247 0.0279 0.47 0.7942 0.9865 3034593 ChemDiv3_012041 CCc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D08 compound treatment 0.243 0.0148 0.21 0.243 0.0239 0.4 0.4332 0.9552 3120439 ChemDiv3_012042 CCOC(=O)C1=Cc2sc3CCCCc3c2CS1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D09 compound treatment 0.317 0.0888 1.27 0.313 0.0939 1.58 2.0124 0.9943 3120440 ChemDiv3_012043 CCc1ccc(NC(=O)CN2C(=O)CCc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D10 compound treatment 0.168 -0.0602 -0.86 0.178 -0.0411 -0.69 -1.0968 -0.9939 3034598 ChemDiv3_012044 O=C(CSc1ccc2nnc(c3ccccn3)n2n1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D11 compound treatment 0.295 0.0668 0.96 0.318 0.0989 1.66 1.8493 0.9655 3120441 ChemDiv3_012045 COc1ccc(cc1)n2cc(C(=O)N3CCCN(Cc4ccccc4F)C3)c5ccccc5c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D12 compound treatment 0.342 0.114 1.63 0.296 0.0769 1.29 2.0635 0.9934 3034601 ChemDiv3_012046 CCOc1ccccc1NC(=O)CSc2ccc(nn2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D13 compound treatment 0.286 0.0578 0.83 0.22 9.06E-4 0.02 0.5952 0.72 3120442 ChemDiv3_012047 CCc1ccc(NS(=O)(=O)c2ccc3NC(=O)CSc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D14 compound treatment 0.329 0.101 1.44 0.288 0.0689 1.16 1.8371 0.994 3034604 ChemDiv3_012048 NC(=O)CSc1ccc(nn1)c2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D15 compound treatment 0.327 0.0988 1.41 0.312 0.0929 1.56 2.1017 0.9988 3120443 ChemDiv3_012049 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D16 compound treatment 0.303 0.0748 1.07 0.284 0.0649 1.09 1.5267 1.0 3034677 ChemDiv3_012050 Cc1ccc(cc1)C(=O)NCCc2nnc3ccc(SCC(=O)NC4CCCCC4)nn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D17 compound treatment 0.293 0.0648 0.93 0.298 0.0789 1.32 1.5917 0.9847 3120444 ChemDiv3_012051 O=C(N(CCC#N)c1ccccc1)c2ccc3c(=O)n4CCCCc4nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D18 compound treatment 0.278 0.0498 0.71 0.27 0.0509 0.85 1.1077 0.9959 3120445 ChemDiv3_012052 COc1ccc(OC)c(c1)S(=O)(=O)NCCc2sc(nc2C)c3ccc(OC)c(OC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D19 compound treatment 0.302 0.0738 1.06 0.288 0.0689 1.16 1.564 0.999 3034682 ChemDiv3_012053 Cc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D20 compound treatment 0.289 0.0608 0.87 0.285 0.0659 1.11 1.3969 0.9929 3120446 ChemDiv3_012054 CN(C1CCCCC1)S(=O)(=O)c2csc(c2)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D21 compound treatment 0.313 0.0848 1.21 0.271 0.0519 0.87 1.4735 0.9868 3034685 ChemDiv3_012055 C(Sc1nncn2c3ccsc3cc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D22 compound treatment 0.258 0.0298 0.43 0.261 0.0419 0.7 0.7986 0.9711 3120447 ChemDiv3_012056 CC1CN(CCc2ccccc2)c3nc4n(C)c(=O)n(CC(=O)N)c(=O)c4n3C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D23 mock treatment 0.242 0.0138 0.2 0.232 0.0129 0.22 0.2926 0.9989 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 D24 mock treatment 0.241 0.0128 0.18 0.215 -0.00409 -0.07 0.0807 0.4131 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E01 compound treatment 0.24 0.0118 0.17 0.251 0.0319 0.54 0.4978 0.8868 3034687 ChemDiv3_012057 O=c1cc([nH]c(=O)n1C2CCCCC2)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E02 compound treatment 0.268 0.0398 0.57 0.298 0.0789 1.32 1.3388 0.9288 3120448 ChemDiv3_012058 CC1CCc2c(C1)sc3nc([nH]c(=O)c23)c4cc5ccccc5oc4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E03 compound treatment 0.301 0.0728 1.04 0.267 0.0479 0.8 1.3047 0.9919 3120449 ChemDiv3_012059 O=C(Nc1cccc(c1)c2nc3cccnc3s2)C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E04 compound treatment 0.308 0.0798 1.14 0.298 0.0789 1.32 1.7434 0.9973 3034691 ChemDiv3_012060 CCc1ccc(NS(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E05 compound treatment 0.291 0.0628 0.9 0.3 0.0809 1.36 1.5952 0.9798 3034770 ChemDiv3_012061 CS(=O)(=O)NCC(N1CCN(Cc2ccccc2)CC1)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E06 compound treatment 0.297 0.0688 0.98 0.332 0.113 1.9 2.0357 0.9534 3120450 ChemDiv3_012062 CC1CN(C(=O)NCc2ccccc2)c3cc(C)ccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E07 compound treatment 0.266 0.0378 0.54 0.26 0.0409 0.69 0.8676 0.993 3034773 ChemDiv3_012063 COc1ccc(cc1)c2noc(=O)n2Cc3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E08 compound treatment 0.241 0.0128 0.18 0.299 0.0799 1.34 1.0776 0.7961 3120451 ChemDiv3_012064 CC1CCc2c(C1)cc(c3ccccc3)n2c4ccc(cc4)C(=O)NCCN5CCN(C)CC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E09 compound treatment 0.267 0.0388 0.55 0.227 0.00791 0.13 0.4861 0.8522 3034777 ChemDiv3_012065 O=c1n(CCc2ccccc2)c(SCC#N)nc3nccnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E10 compound treatment 0.266 0.0378 0.54 0.274 0.0549 0.92 1.0338 0.9677 3120620 ChemDiv3_012066 COc1cccc(NC(=O)Cn2c(=O)c3cccn3c4ccccc24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E11 compound treatment 0.272 0.0438 0.63 0.249 0.0299 0.5 0.7977 0.994 3120621 ChemDiv3_012067 CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)NCCN3CCN(CC3)c4ccccc4F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E12 compound treatment 0.284 0.0558 0.8 0.258 0.0389 0.65 1.0259 0.9951 3034781 ChemDiv3_012068 O=C(Cn1c(=O)c2cccn2c3ccccc13)NCCCN4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E13 compound treatment 0.303 0.0748 1.07 0.227 0.00791 0.13 0.8502 0.7888 3120622 ChemDiv3_012069 Cn1c(cc2c(=O)n3ccccc3nc12)C(=O)N4COCC4(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E14 compound treatment 0.272 0.0438 0.63 0.255 0.0359 0.6 0.869 0.9998 3034785 ChemDiv3_012070 CCn1cc(CCCC(=O)N2CCc3ccccc23)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E15 compound treatment 0.255 0.0268 0.38 0.244 0.0249 0.42 0.5665 0.999 3120623 ChemDiv3_012071 CCc1nnc(NC(=O)c2cc(cn2C)S(=O)(=O)N3CCc4ccccc34)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E16 compound treatment 0.266 0.0378 0.54 0.229 0.00991 0.17 0.4997 0.8838 3120624 ChemDiv3_012072 CCn1cc2CCc3oc(C(=O)Nc4ccc(Cl)cc4)c(C)c3-c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E17 compound treatment 0.244 0.0158 0.23 0.266 0.0469 0.79 0.7163 0.8746 3034854 ChemDiv3_012073 Cc1ccc(cc1)c2nsc(SCC(=O)c3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E18 compound treatment 0.299 0.0708 1.01 0.264 0.0449 0.75 1.2488 0.9894 3120625 ChemDiv3_012074 O=C(NCc1ccccc1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E19 compound treatment 0.252 0.0238 0.34 0.245 0.0259 0.43 0.548 0.9926 3034857 ChemDiv3_012075 COC(=O)c1ccc(CSc2nc(ns2)c3ccc(OC)cc3)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E20 compound treatment 0.284 0.0558 0.8 0.233 0.0139 0.23 0.7292 0.8772 3120626 ChemDiv3_012076 CCOc1ccc(cc1)c2cn3c(n2)sc4cc(ccc43)C(=O)N(C)Cc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E21 compound treatment 0.241 0.0128 0.18 0.271 0.0519 0.87 0.7453 0.8373 3034861 ChemDiv3_012077 COC(=O)c1sccc1NC(=O)Cc2noc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E22 compound treatment 0.239 0.0108 0.15 0.246 0.0269 0.45 0.4284 0.8977 3120627 ChemDiv3_012078 Fc1ccc(cc1)c2cc(on2)C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E23 mock treatment 0.257 0.0288 0.41 0.23 0.0109 0.18 0.4205 0.9334 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 E24 mock treatment 0.223 -0.00522 -0.07 0.225 0.00591 0.1 0.0173 0.1395 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F01 compound treatment 0.256 0.0278 0.4 0.296 0.0769 1.29 1.1937 0.8839 3034864 ChemDiv3_012079 Cc1cc(NC(=O)c2cc(no2)c3ccc(F)cc3)nn1CC(=O)NCc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F02 compound treatment 0.262 0.0338 0.48 0.281 0.0619 1.04 1.0764 0.9393 3120628 ChemDiv3_012080 CCc1ccc(NC(=O)CSc2nncn3c4ccoc4cc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F03 compound treatment 0.277 0.0488 0.7 0.283 0.0639 1.07 1.2518 0.9783 3120629 ChemDiv3_012081 Cc1cccc(NC(=O)Cn2cnc3c4ccccc4oc3c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F04 compound treatment 0.301 0.0728 1.04 0.265 0.0459 0.77 1.2809 0.989 3034869 ChemDiv3_012082 Cc1cc2c(cc3c(SCC(=O)Nc4ccccc4F)nncn23)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F05 compound treatment 0.34 0.112 1.6 0.345 0.126 2.11 2.6248 0.9905 3120630 ChemDiv3_012083 CN(c1cccc(C)c1)S(=O)(=O)c2ccc3NC(=O)COc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F06 compound treatment 0.337 0.109 1.56 0.306 0.0869 1.46 2.1316 0.9995 3120631 ChemDiv3_012084 CC(C)NC(=O)Cn1c(=O)c2cccn2c3cccnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F07 compound treatment 0.324 0.0958 1.37 0.314 0.0949 1.59 2.0951 0.9972 3034943 ChemDiv3_012085 COc1cccc(CNS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F08 compound treatment 0.305 0.0768 1.1 0.257 0.0379 0.64 1.2265 0.9663 3120632 ChemDiv3_012086 CCOC(=O)c1cn2CC(CC)Oc3ccc(C)c(c1=O)c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F09 compound treatment 0.318 0.0898 1.28 0.25 0.0309 0.52 1.2749 0.9205 3034946 ChemDiv3_012087 O=C(CN1C(=O)CCc2ccccc12)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F10 compound treatment 0.311 0.0828 1.18 0.291 0.0719 1.21 1.6907 1.0 3120633 ChemDiv3_012088 N#CCSc1ccc2nnc(c3ccncc3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F11 compound treatment 0.309 0.0808 1.16 0.311 0.0919 1.54 1.9078 0.9899 3120634 ChemDiv3_012089 COc1cccc(c1)n2cc(C(=O)N(CC(C)C)CC(C)C)c3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F12 compound treatment 0.331 0.103 1.47 0.298 0.0789 1.32 1.976 0.9986 3034949 ChemDiv3_012090 O=C(CSc1ccc(nn1)c2cccs2)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F13 compound treatment 0.351 0.123 1.76 0.285 0.0659 1.11 2.024 0.9752 3120635 ChemDiv3_012091 O=C1CSc2cc(ccc2N1)S(=O)(=O)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F14 compound treatment 0.303 0.0748 1.07 0.276 0.0569 0.96 1.4317 0.9984 3034952 ChemDiv3_012092 O=C(CSc1ccc(nn1)c2ccncc2)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F15 compound treatment 0.229 7.81E-4 0.01 0.286 0.0669 1.12 0.802 0.7141 3120636 ChemDiv3_012093 CC1CN(C(=O)C)c2ccc(cc2S1)S(=O)(=O)Nc3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F16 compound treatment 0.299 0.0708 1.01 0.276 0.0569 0.96 1.3913 0.9996 3120637 ChemDiv3_012094 COc1ccc(cc1)C(=O)NCCc2nnc3ccc(SCC(=O)Nc4ccc(C)cc4C)nn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F17 compound treatment 0.308 0.0798 1.14 0.229 0.00991 0.17 0.9245 0.8017 3034956 ChemDiv3_012095 CC(C)CN(CC(C)C)C(=O)c1noc-2c1COc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F18 compound treatment 0.283 0.0548 0.78 0.28 0.0609 1.02 1.2769 0.9914 3120638 ChemDiv3_012096 COc1ccc(cc1OC)c2nc(C)c(CCNS(=O)(=O)c3ccc4OCCOc4c3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F19 compound treatment 0.236 0.00778 0.11 0.266 0.0469 0.79 0.6354 0.7991 3035461 ChemDiv3_012097 CN(CC(=O)N1CCC(=CC1)c2ccccc2)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F20 compound treatment 0.249 0.0208 0.3 0.286 0.0669 1.12 1.0042 0.8645 3120639 ChemDiv3_012098 CCN(CC)CCNc1ccc2nnc(CCNC(=O)c3ccc(C)cc3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F21 compound treatment 0.266 0.0378 0.54 0.302 0.0829 1.39 1.3661 0.9151 3035465 ChemDiv3_012099 CCC(Sc1nncn2c3ccsc3cc12)C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F22 compound treatment 0.233 0.00478 0.07 0.273 0.0539 0.9 0.6881 0.7584 3120640 ChemDiv3_012100 FC(F)(F)c1cccc(NC(=O)Cc2nc(no2)c3cccs3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F23 mock treatment 0.265 0.0368 0.53 0.232 0.0129 0.22 0.5252 0.9231 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 F24 mock treatment 0.251 0.0228 0.33 0.226 0.00691 0.12 0.3124 0.9032 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G01 compound treatment 0.281 0.0528 0.75 0.283 0.0639 1.07 1.2923 0.9852 3034356 ChemDiv3_012101 CCc1ccc(Nc2cc(=O)n(C3CCCCC3)c(=O)[nH]2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G02 compound treatment 0.295 0.0668 0.96 0.25 0.0309 0.52 1.0422 0.9588 3120641 ChemDiv3_012102 COc1cccc2cc(c3nc4sc(C(=O)Nc5cccc(F)c5)c(C)c4c(=O)[nH]3)c(=O)oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G03 compound treatment 0.282 0.0538 0.77 0.273 0.0539 0.9 1.1837 0.9967 3034363 ChemDiv3_012103 CCC(=O)Nc1cc(ccc1C)c2nc3cccnc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G04 compound treatment 0.304 0.0758 1.08 0.24 0.0209 0.35 1.0146 0.8905 3120642 ChemDiv3_012104 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G05 compound treatment 0.303 0.0748 1.07 0.298 0.0789 1.32 1.6928 0.9944 3120643 ChemDiv3_012105 O=S(=O)(NCC(N1CCN(Cc2ccccc2)CC1)c3cccnc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G06 compound treatment 0.303 0.0748 1.07 0.28 0.0609 1.02 1.4792 0.9997 3034368 ChemDiv3_012106 CC1CN(C(=O)NC2(CC3CC4CC(C3)C2)C4)c5cc(Cl)ccc5O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G07 compound treatment 0.324 0.0958 1.37 0.299 0.0799 1.34 1.9171 0.9999 3120644 ChemDiv3_012107 COc1ccc(cc1)c2noc(=O)n2CC(=O)N3CCC(C)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G08 compound treatment 0.307 0.0788 1.13 0.285 0.0659 1.11 1.579 1.0 3034371 ChemDiv3_012108 COC(=O)c1ccc(c2ccco2)n1CC(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G09 compound treatment 0.3 0.0718 1.03 0.276 0.0569 0.96 1.4014 0.9993 3120645 ChemDiv3_012109 CCC(Sc1nc2nccnc2c(=O)n1CCc3ccccc3)C(=O)Nc4ccc(CC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G10 compound treatment 0.304 0.0758 1.08 0.299 0.0799 1.34 1.7148 0.9944 3034438 ChemDiv3_012110 O=C(Cn1c(=O)c2cccn2c3ccccc13)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G11 compound treatment 0.297 0.0688 0.98 0.238 0.0189 0.32 0.9201 0.89 3120646 ChemDiv3_012111 CN(Cc1ccco1)S(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G12 compound treatment 0.315 0.0868 1.24 0.27 0.0509 0.85 1.4819 0.9834 3034441 ChemDiv3_012112 CCc1ccccc1NC(=O)CCn2c(=O)c3cccn3c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G13 compound treatment 0.286 0.0578 0.83 0.295 0.0759 1.27 1.4853 0.978 3120647 ChemDiv3_012113 CCc1ccccc1NC(=O)c2cc3c(=O)n4ccccc4nc3n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G14 compound treatment 0.258 0.0298 0.43 0.262 0.0429 0.72 0.8104 0.9686 3034445 ChemDiv3_012114 CCn1cc(CCCC(=O)N2CCCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G15 compound treatment 0.246 0.0178 0.25 0.257 0.0379 0.64 0.6297 0.9191 3120809 ChemDiv3_012115 CN(Cc1ccccc1)S(=O)(=O)c2ccc3N(CCOc3c2)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G16 compound treatment 0.254 0.0258 0.37 0.228 0.00891 0.15 0.3665 0.921 3120810 ChemDiv3_012116 CCOC(=O)c1ccc(NC(=O)c2oc3CCc4cn(Cc5ccc(C)cc5)nc4-c3c2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G17 compound treatment 0.291 0.0628 0.9 0.226 0.00691 0.12 0.7169 0.7918 3034447 ChemDiv3_012117 Cc1cccc(c1)c2nsc(SCC(=O)N3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G18 compound treatment 0.276 0.0478 0.68 0.253 0.0339 0.57 0.8857 0.9959 3120811 ChemDiv3_012118 O=C(NC1CCCC1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G19 compound treatment 0.237 0.00878 0.13 0.243 0.0239 0.4 0.3725 0.8861 3034451 ChemDiv3_012119 COc1ccc(cc1)c2nsc(SCC(=O)c3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G20 compound treatment 0.232 0.00378 0.05 0.212 -0.00709 -0.12 -0.0459 -0.3513 3120812 ChemDiv3_012120 CCOc1ccc(cc1)c2cn3c(n2)sc4cc(ccc43)C(=O)N5CCN(C)CC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G21 compound treatment 0.215 -0.0132 -0.19 0.238 0.0189 0.32 0.0907 0.2455 3034454 ChemDiv3_012121 CCOC(=O)N1CCC(CC1)NC(=O)c2nn(C)c-3c2CS(=O)(=O)c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G22 compound treatment 0.255 0.0268 0.38 0.255 0.0359 0.6 0.697 0.9761 3120813 ChemDiv3_012122 Fc1ccc(cc1)c2cc(on2)C(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G23 mock treatment 0.223 -0.00522 -0.07 0.211 -0.00809 -0.14 -0.1488 -0.9602 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 G24 mock treatment 0.238 0.00978 0.14 0.221 0.00191 0.03 0.1216 0.8469 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H01 compound treatment 0.277 0.0488 0.7 0.245 0.0259 0.43 0.8008 0.9741 3120814 ChemDiv3_012123 CC1CCN(CC1)C(=O)Cn2nc(NC(=O)c3cc(no3)c4ccc(F)cc4)cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H02 compound treatment 0.253 0.0248 0.35 0.251 0.0319 0.54 0.6293 0.9799 3034520 ChemDiv3_012124 Cc1ccc(C)c(CSc2nncn3c4ccoc4cc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H03 compound treatment 0.32 0.0918 1.31 0.299 0.0799 1.34 1.8766 0.9999 3120815 ChemDiv3_012125 Fc1ccccc1NC(=O)Cn2cnc3c4ccccc4oc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H04 compound treatment 0.291 0.0628 0.9 0.306 0.0869 1.46 1.6664 0.9729 3034526 ChemDiv3_012126 CCC(Sc1nncn2c3cc(C)oc3cc12)C(=O)NCc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H05 compound treatment 0.322 0.0938 1.34 0.324 0.105 1.76 2.1936 0.991 3120816 ChemDiv3_012127 Cc1cc2NC(=O)COc2cc1S(=O)(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H06 compound treatment 0.277 0.0488 0.7 0.312 0.0929 1.56 1.596 0.9342 3120817 ChemDiv3_012128 CC1=C(SCCO1)C(=O)Nc2ccc(cc2)C(=O)NCc3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H07 compound treatment 0.284 0.0558 0.8 0.286 0.0669 1.12 1.3582 0.986 3034532 ChemDiv3_012129 COc1cc2CCN(C(C)c2cc1OC)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H08 compound treatment 0.311 0.0828 1.18 0.284 0.0649 1.09 1.6076 0.9991 3120818 ChemDiv3_012130 NC(=N)SCc1csc2CCCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H09 compound treatment 0.313 0.0848 1.21 0.302 0.0829 1.39 1.8414 0.9977 3034535 ChemDiv3_012131 Cc1cc(C)cc(NC(=O)CN2C(=O)CCc3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H10 compound treatment 0.324 0.0958 1.37 0.276 0.0569 0.96 1.6441 0.9844 3120819 ChemDiv3_012132 CSc1ccc(nn1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H11 compound treatment 0.287 0.0588 0.84 0.283 0.0639 1.07 1.353 0.9927 3034609 ChemDiv3_012133 COc1cccc(c1)n2cc(C(=O)NCCc3ccc(cc3)S(=O)(=O)N)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H12 compound treatment 0.297 0.0688 0.98 0.252 0.0329 0.55 1.0862 0.9627 3120820 ChemDiv3_012134 O=C(CSc1ccc(nn1)c2ccco2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H13 compound treatment 0.296 0.0678 0.97 0.252 0.0329 0.55 1.0761 0.9644 3034613 ChemDiv3_012135 CCCNS(=O)(=O)c1ccc2NC(=O)CSc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H14 compound treatment 0.322 0.0938 1.34 0.261 0.0419 0.7 1.4459 0.9546 3120821 ChemDiv3_012136 O=C(CSc1ccc(nn1)c2ccncc2)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H15 compound treatment 0.257 0.0288 0.41 0.291 0.0719 1.21 1.1445 0.8975 3120822 ChemDiv3_012137 CC1CN(C(=O)C)c2ccc(cc2S1)S(=O)(=O)N(C)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H16 compound treatment 0.273 0.0448 0.64 0.307 0.0879 1.48 1.4962 0.9302 3034616 ChemDiv3_012138 O=S(=O)(NCCc1nnc2ccc(SCc3ccccc3)nn12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H17 compound treatment 0.329 0.101 1.44 0.291 0.0719 1.21 1.8727 0.9961 3120823 ChemDiv3_012139 CCc1nnc(NC(=O)c2noc-3c2COc4ccc(C)cc34)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H18 compound treatment 0.285 0.0568 0.81 0.235 0.0159 0.27 0.7631 0.8926 3034620 ChemDiv3_012140 COc1ccc(cc1)c2nc(C)c(CCNC(=O)c3cccc(c3)C(F)(F)F)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H19 compound treatment 0.274 0.0458 0.65 0.275 0.0559 0.94 1.1265 0.9845 3120824 ChemDiv3_012141 Cc1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H20 compound treatment 0.303 0.0748 1.07 0.243 0.0239 0.4 1.0401 0.9104 3120825 ChemDiv3_012142 CNc1ccc2nnc(CCNC(=O)c3ccccc3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H21 compound treatment 0.285 0.0568 0.81 0.276 0.0569 0.96 1.2497 0.9967 3034623 ChemDiv3_012143 CCC1CCCCN1C(=O)CSc2nnc(C)n3c4ccsc4cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H22 compound treatment 0.271 0.0428 0.61 0.273 0.0539 0.9 1.0725 0.9819 3120826 ChemDiv3_012144 FC(F)(F)c1cccc(NC(=O)NCc2noc3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H23 mock treatment 0.236 0.00778 0.11 0.234 0.0149 0.25 0.2556 0.9335 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 H24 mock treatment 0.205 -0.0232 -0.33 0.224 0.00491 0.08 -0.1766 -0.5162 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I01 compound treatment 0.256 0.0278 0.4 0.276 0.0569 0.96 0.9564 0.9245 3035848 ChemDiv3_012145 CCC(=O)Nc1ccc(cc1)c2nc3cccnc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I02 compound treatment 0.256 0.0278 0.4 0.25 0.0309 0.52 0.6478 0.9913 3035849 ChemDiv3_012146 CN1CCN(CC1)c2ccccc2NC(=O)c3sc4nc5CCCCCn5c(=O)c4c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I03 compound treatment 0.268 0.0398 0.57 0.295 0.0759 1.27 1.3032 0.934 3035850 ChemDiv3_012147 O=S(=O)(Nc1ccc(cc1)c2nc3cccnc3s2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I04 compound treatment 0.265 0.0368 0.53 0.292 0.0729 1.22 1.2373 0.9289 3035851 ChemDiv3_012148 CC1Cc2ccccc2N1S(=O)(=O)c3c(C)[nH]c(=O)[nH]c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I05 compound treatment 0.319 0.0908 1.3 0.308 0.0889 1.49 1.9733 0.9976 3035852 ChemDiv3_012149 CCCC(=O)Nc1nn2c(nnc2s1)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I06 compound treatment 0.248 0.0198 0.28 0.302 0.0829 1.39 1.184 0.8338 3035853 ChemDiv3_012150 CCOC(=O)c1c(NC(=O)N2CCOc3ccc(Cl)cc23)sc4CCCCc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I07 compound treatment 0.275 0.0468 0.67 0.287 0.0679 1.14 1.2791 0.9678 3035854 ChemDiv3_012151 Cc1ccccc1Cn2c(noc2=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I08 compound treatment 0.286 0.0578 0.83 0.264 0.0449 0.75 1.1174 0.9989 3120827 ChemDiv3_012152 COC(=O)c1ccc(c2ccco2)n1CC(=O)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I09 compound treatment 0.303 0.0748 1.07 0.257 0.0379 0.64 1.2062 0.9692 3120828 ChemDiv3_012153 COc1ccc(Cl)cc1NC(=O)CSc2nc3nccnc3c(=O)n2CC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I10 compound treatment 0.312 0.0838 1.2 0.259 0.0399 0.67 1.321 0.9622 3035855 ChemDiv3_012154 Clc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I11 compound treatment 0.292 0.0638 0.91 0.262 0.0429 0.72 1.1543 0.9931 3120829 ChemDiv3_012155 Nc1ncc(Br)cc1S(=O)(=O)NCCC(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I12 compound treatment 0.282 0.0538 0.77 0.249 0.0299 0.5 0.8989 0.9786 3035856 ChemDiv3_012156 O=C(CCCn1c(=O)c2cccn2c3ccccc13)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I13 compound treatment 0.274 0.0458 0.65 0.222 0.00291 0.05 0.4975 0.7577 3120830 ChemDiv3_012157 CNC(=O)c1cc2c(=O)n3cccc(C)c3nc2n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I14 compound treatment 0.299 0.0708 1.01 0.265 0.0459 0.77 1.2607 0.9909 3120831 ChemDiv3_012158 CCn1cc(CCCC(=O)NCCc2ccc(Cl)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I15 compound treatment 0.294 0.0658 0.94 0.226 0.00691 0.12 0.7473 0.7883 3035857 ChemDiv3_012159 CCc1ccc(NS(=O)(=O)c2ccc3N(CCOc3c2)C(=O)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I16 compound treatment 0.221 -0.00722 -0.1 0.258 0.0389 0.65 0.3887 0.588 3120832 ChemDiv3_012160 Cc1c(oc2CCc3cn(Cc4ccc(C)cc4)nc3-c12)C(=O)NCCCN5CCCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I17 compound treatment 0.224 -0.00422 -0.06 0.253 0.0339 0.57 0.3597 0.6286 3035858 ChemDiv3_012161 Cc1cccc(c1)c2nsc(SCC(=O)OCc3ccccc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I18 compound treatment 0.242 0.0138 0.2 0.187 -0.0321 -0.54 -0.2415 -0.421 3120833 ChemDiv3_012162 CCCNC(=O)c1ccc2c(c1)sc3nc(cn32)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I19 compound treatment 0.235 0.00678 0.1 0.247 0.0279 0.47 0.3998 0.8358 3120834 ChemDiv3_012163 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)NCCN4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I20 compound treatment 0.28 0.0518 0.74 0.227 0.00791 0.13 0.6176 0.8207 3035859 ChemDiv3_012164 COc1cccc(c1)c2cc(on2)C(=O)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I21 compound treatment 0.219 -0.00922 -0.13 0.226 0.00691 0.12 -0.0113 -0.0642 3120835 ChemDiv3_012165 COc1ccc(cc1Nc2nc3ccccc3n4c(C)nnc24)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I22 compound treatment 0.219 -0.00922 -0.13 0.23 0.0109 0.18 0.0362 0.1604 3035860 ChemDiv3_012166 CCC(C)NC(=O)c1cc(no1)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I23 mock treatment 0.215 -0.0132 -0.19 0.229 0.00991 0.17 -0.0161 -0.0641 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 I24 mock treatment 0.206 -0.0222 -0.32 0.196 -0.0231 -0.39 -0.4988 -0.9951 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J01 compound treatment 0.221 -0.00722 -0.1 0.272 0.0529 0.89 0.5549 0.6207 3120836 ChemDiv3_012167 COCC(C)NC(=O)Cn1nc(C)c(NC(=O)c2cc(no2)c3ccccc3F)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J02 compound treatment 0.269 0.0408 0.58 0.26 0.0409 0.69 0.8979 0.9967 3035861 ChemDiv3_012168 O=C(CSc1nncn2c3ccoc3cc12)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J03 compound treatment 0.292 0.0638 0.91 0.253 0.0339 0.57 1.0475 0.9742 3120837 ChemDiv3_012169 CC(=O)Nc1ccc(NC(=O)Cn2cnc3c4ccccc4oc3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J04 compound treatment 0.232 0.00378 0.05 0.27 0.0509 0.85 0.6424 0.7504 3035862 ChemDiv3_012170 Cc1nnc(SCc2ccc(F)cc2Cl)c3cc4occc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J05 compound treatment 0.325 0.0968 1.38 0.298 0.0789 1.32 1.9153 0.9998 3121017 ChemDiv3_012171 CC1CCCCN1S(=O)(=O)c2cc3OCC(=O)Nc3cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J06 compound treatment 0.305 0.0768 1.1 0.306 0.0869 1.46 1.808 0.9902 3121018 ChemDiv3_012172 CCCNC(=O)c1ccc(CS(=O)c2ccc(Br)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J07 compound treatment 0.339 0.111 1.58 0.32 0.101 1.69 2.318 0.9994 3035863 ChemDiv3_012173 O=c1ccc2cc(ccc2[nH]1)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J08 compound treatment 0.285 0.0568 0.81 0.22 9.06E-4 0.02 0.5851 0.7202 3121019 ChemDiv3_012174 CCOC(=O)N1CCC(CC1)NC(=O)CCc2cn(Cc3ccccc3C)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J09 compound treatment 0.314 0.0858 1.23 0.239 0.0199 0.33 1.1039 0.868 3035864 ChemDiv3_012175 O=C(CN1C(=O)CCc2ccccc12)NC3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J10 compound treatment 0.3 0.0718 1.03 0.242 0.0229 0.38 0.9979 0.9102 3121020 ChemDiv3_012176 CSc1ccc(nn1)c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J11 compound treatment 0.266 0.0378 0.54 0.27 0.0509 0.85 0.9863 0.9756 3121021 ChemDiv3_012177 CC(=O)N1CCSc2cc(ccc12)S(=O)(=O)Nc3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J12 compound treatment 0.287 0.0588 0.84 0.285 0.0659 1.11 1.3767 0.9908 3035865 ChemDiv3_012178 CCOC(=O)N1CCN(CC1)C(=O)CSc2ccc(nn2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J13 compound treatment 0.282 0.0538 0.77 0.281 0.0619 1.04 1.2787 0.9891 3121022 ChemDiv3_012179 O=C1CSc2cc(ccc2N1)S(=O)(=O)N3CCC(=CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J14 compound treatment 0.28 0.0518 0.74 0.279 0.0599 1.01 1.2347 0.9887 3121023 ChemDiv3_012180 O=C(CSc1ccc(nn1)c2ccncc2)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J15 compound treatment 0.331 0.103 1.47 0.282 0.0629 1.06 1.7861 0.9868 3035866 ChemDiv3_012181 CC1CN(C(=O)C)c2ccc(cc2S1)S(=O)(=O)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J16 compound treatment 0.272 0.0438 0.63 0.26 0.0409 0.69 0.9283 0.9989 3121024 ChemDiv3_012182 O=S(=O)(NCCc1nnc2ccc(SCC#N)nn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J17 compound treatment 0.264 0.0358 0.51 0.289 0.0699 1.17 1.1916 0.9308 3121025 ChemDiv3_012183 CCOC(=O)c1ccccc1NC(=O)c2nc(c3ccc(C)cc3)n4CCCCCc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J18 compound treatment 0.276 0.0478 0.68 0.258 0.0389 0.65 0.945 0.9997 3035867 ChemDiv3_012184 COc1ccc(cc1)c2nc(C)c(CCNC(=O)C(C)(C)C)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J19 compound treatment 0.24 0.0118 0.17 0.257 0.0379 0.64 0.569 0.8646 3121026 ChemDiv3_012185 CCN(Cc1ccccc1)C(=O)Cn2cc3CCc4oc(C(=O)N5CCCC5)c(C)c4-c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J20 compound treatment 0.287 0.0588 0.84 0.255 0.0359 0.6 1.0207 0.9867 3035868 ChemDiv3_012186 O=C(NCCc1nnc2ccc(nn12)N3CCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J21 compound treatment 0.235 0.00678 0.1 0.211 -0.00809 -0.14 -0.0275 -0.1646 3121027 ChemDiv3_012187 Cc1ccc(NC(=O)CSc2nnc(C)n3c4ccsc4cc23)cc1F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J22 compound treatment 0.217 -0.0112 -0.16 0.24 0.0209 0.35 0.1346 0.349 3035869 ChemDiv3_012188 CCOC(=O)N1CCC(CC1)NC(=O)NCc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J23 mock treatment 0.224 -0.00422 -0.06 0.252 0.0329 0.55 0.3479 0.6261 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 J24 mock treatment 0.238 0.00978 0.14 0.211 -0.00809 -0.14 0.0029 0.0147 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K01 compound treatment 0.248 0.0198 0.28 0.285 0.0659 1.11 0.9823 0.8603 3121028 ChemDiv3_012189 CC(C)C(=O)Nc1ccc(cc1)c2nc3cccnc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K02 compound treatment 0.257 0.0288 0.41 0.268 0.0489 0.82 0.8715 0.9491 3035870 ChemDiv3_012190 Cc1c(sc2nc3CCCCn3c(=O)c12)C(=O)N4CCN(CC4)c5ccccc5F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K03 compound treatment 0.25 0.0218 0.31 0.231 0.0119 0.2 0.3616 0.977 3121029 ChemDiv3_012191 CS(=O)(=O)Nc1ccc(cc1)c2nc3cccnc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K04 compound treatment 0.278 0.0498 0.71 0.275 0.0559 0.94 1.167 0.9907 3121030 ChemDiv3_012192 O=C(NCc1ccccc1)C2CCCN(C2)C(=O)N3CCOc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K05 compound treatment 0.268 0.0398 0.57 0.261 0.0419 0.7 0.8997 0.9945 3035871 ChemDiv3_012193 COc1ccc(cc1)c2nnc3sc(NC(=O)C(C)C)nn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K06 compound treatment 0.264 0.0358 0.51 0.248 0.0289 0.49 0.705 0.9996 3121031 ChemDiv3_012194 CC(C)c1ccc(cc1)N2C(=O)CSCC2(C(=O)NC3CCCCC3)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K07 compound treatment 0.256 0.0278 0.4 0.259 0.0399 0.67 0.7546 0.9689 3035872 ChemDiv3_012195 Fc1ccc(Cn2c(noc2=O)c3cccs3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K08 compound treatment 0.233 0.00478 0.07 0.266 0.0469 0.79 0.605 0.7656 3121032 ChemDiv3_012196 COC(=O)c1ccc(c2ccco2)n1CC(=O)NCCN3CCN(C)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K09 compound treatment 0.263 0.0348 0.5 0.251 0.0319 0.54 0.7305 0.9993 3035873 ChemDiv3_012197 CN(Cc1ccccc1)C(=O)CN(C)S(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K10 compound treatment 0.316 0.0878 1.26 0.288 0.0689 1.16 1.7056 0.9992 3121033 ChemDiv3_012198 O=C(Cn1c(=O)c2cccn2c3ccccc13)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K11 compound treatment 0.283 0.0548 0.78 0.256 0.0369 0.62 0.9921 0.9932 3121034 ChemDiv3_012199 O=C(Nc1ccccc1)c2c[nH]c(=O)n(c3ccccc3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K12 compound treatment 0.238 0.00978 0.14 0.279 0.0599 1.01 0.8099 0.7978 3035874 ChemDiv3_012200 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K13 compound treatment 0.283 0.0548 0.78 0.274 0.0549 0.92 1.2057 0.9967 3121035 ChemDiv3_012201 CC1Cc2ccccc2N1C(=O)c3cc4c(=O)n5cccc(C)c5nc4n3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K14 compound treatment 0.19 -0.0382 -0.55 0.238 0.0189 0.32 -0.1622 -0.2566 3121036 ChemDiv3_012202 CCn1cc(CCCC(=O)NC2CCC(C)CC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K15 compound treatment 0.249 0.0208 0.3 0.235 0.0159 0.27 0.399 0.9986 3035875 ChemDiv3_012203 CC1CCCCN1S(=O)(=O)c2ccc3N(CCOc3c2)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K16 compound treatment 0.056 -0.172 -2.46 0.049 -0.17 -2.85 -3.7605 -0.9973 3121037 ChemDiv3_012204 CCN1CCCC1CNC(=O)c2ccc3c(c2)sc4nc(cn43)c5ccc(C)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K17 compound treatment 0.244 0.0158 0.23 0.252 0.0329 0.55 0.5501 0.9221 3035876 ChemDiv3_012205 COc1ccc(cc1)C(=O)CSc2nc(ns2)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K18 compound treatment 0.274 0.0458 0.65 0.241 0.0219 0.37 0.723 0.9628 3121038 ChemDiv3_012206 O=C(NCCc1ccccc1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K19 compound treatment 0.245 0.0168 0.24 0.227 0.00791 0.13 0.2636 0.9609 3035877 ChemDiv3_012207 O=C(Cc1noc2ccccc12)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K20 compound treatment 0.248 0.0198 0.28 0.233 0.0139 0.23 0.3651 0.9954 3121039 ChemDiv3_012208 COc1cccc(c1)c2cc(on2)C(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K21 compound treatment 0.272 0.0438 0.63 0.261 0.0419 0.7 0.9402 0.9983 3035878 ChemDiv3_012209 Cc1nnc2c(NCCCN3CCN(CC3)c4cc(Cl)ccc4C)nc5ccccc5n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K22 compound treatment 0.242 0.0138 0.2 0.228 0.00891 0.15 0.2451 0.9907 3121040 ChemDiv3_012210 CC(C)CNC(=O)c1cc(no1)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K23 mock treatment 0.19 -0.0382 -0.55 0.201 -0.0181 -0.3 -0.6013 -0.9615 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 K24 mock treatment 0.195 -0.0332 -0.48 0.203 -0.0161 -0.27 -0.527 -0.9642 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L01 compound treatment 0.244 0.0158 0.23 0.266 0.0469 0.79 0.7163 0.8746 3035879 ChemDiv3_012211 CCn1cnc2c3ccccc3oc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L02 compound treatment 0.283 0.0548 0.78 0.296 0.0769 1.29 1.4668 0.9714 3121041 ChemDiv3_012212 CCN(Cc1ccccc1)C(=O)CSc2nncn3c4ccoc4cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L03 compound treatment 0.287 0.0588 0.84 0.316 0.0969 1.63 1.7446 0.9529 3121042 ChemDiv3_012213 O=C(Cn1cnc2c3ccccc3oc2c1=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L04 compound treatment 0.271 0.0428 0.61 0.289 0.0699 1.17 1.2624 0.9539 3035880 ChemDiv3_012214 CCC(Sc1nnc(C)n2c3cc(C)oc3cc12)C(=O)Nc4cccc(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L05 compound treatment 0.231 0.00278 0.04 0.275 0.0559 0.94 0.6916 0.7364 3121043 ChemDiv3_012215 Cc1cc2NC(=O)COc2cc1S(=O)(=O)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L06 compound treatment 0.247 0.0188 0.27 0.248 0.0289 0.49 0.533 0.9611 3121044 ChemDiv3_012216 Clc1ccc(cc1)S(=O)Cc2ccc(o2)C(=O)Nc3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L07 compound treatment 0.292 0.0638 0.91 0.249 0.0299 0.5 1.0 0.9604 3035881 ChemDiv3_012217 O=C1CN(CC(=O)N1CCc2ccccc2)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L08 compound treatment 0.297 0.0688 0.98 0.271 0.0519 0.87 1.3117 0.9982 3121045 ChemDiv3_012218 Cc1cc(C)cc(NC(=O)CSc2ccc3nnc(c4cccs4)n3n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L09 compound treatment 0.273 0.0448 0.64 0.303 0.0839 1.41 1.4487 0.9364 3121226 ChemDiv3_012219 COc1cc2CCN(C(C)c2cc1OC)C(=O)CN3C(=O)CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L10 compound treatment 0.28 0.0518 0.74 0.307 0.0879 1.48 1.567 0.9492 3035882 ChemDiv3_012220 C(Sc1ccc(nn1)c2cccs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L11 compound treatment 0.262 0.0338 0.48 0.282 0.0629 1.06 1.0882 0.9372 3035883 ChemDiv3_012221 COC(=O)Cn1c(=O)n(C)c2nc3N(CCn3c2c1=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L12 compound treatment 0.269 0.0408 0.58 0.255 0.0359 0.6 0.8386 0.9999 3121227 ChemDiv3_012222 O=C(CSc1ccc(nn1)c2cccs2)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L13 compound treatment 0.229 7.81E-4 0.01 0.261 0.0419 0.7 0.5052 0.7183 3036045 ChemDiv3_012223 O=C1CSc2cc(ccc2N1)S(=O)(=O)N3CCC(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L14 compound treatment 0.243 0.0148 0.21 0.277 0.0579 0.97 0.8367 0.8413 3036047 ChemDiv3_012224 O=C(CSc1ccc(nn1)c2ccncc2)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L15 compound treatment 0.283 0.0548 0.78 0.233 0.0139 0.23 0.7191 0.8795 3036048 ChemDiv3_012225 CC1CN(C(=O)C)c2ccc(cc2S1)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L16 compound treatment 0.258 0.0298 0.43 0.278 0.0589 0.99 1.0003 0.9292 3036050 ChemDiv3_012226 Cc1ccc(cc1)S(=O)(=O)NCCc2nnc3ccc(SCC(=O)N4CCCC4)nn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L17 compound treatment 0.242 0.0138 0.2 0.287 0.0679 1.14 0.9453 0.8173 3036051 ChemDiv3_012227 CN(C(=O)c1nc(c2ccc(C)cc2)n3CCCCCc13)c4cc(C)ccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L18 compound treatment 0.262 0.0338 0.48 0.253 0.0339 0.57 0.7441 0.9967 3036052 ChemDiv3_012228 Cc1nc(sc1CCNC(=O)c2c(F)cccc2F)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L19 compound treatment 0.286 0.0578 0.83 0.298 0.0789 1.32 1.5209 0.9742 3036054 ChemDiv3_012229 CNC(=O)Cn1cc2CCc3oc(C(=O)N4CCCC4)c(C)c3-c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L20 compound treatment 0.275 0.0468 0.67 0.264 0.0449 0.75 1.0061 0.9982 3036108 ChemDiv3_012230 Cc1cccc(c1)N2CCCn3c2nc4n(C)c(=O)n(C)c(=O)c34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L21 compound treatment 0.261 0.0328 0.47 0.274 0.0549 0.92 0.9832 0.9509 3036109 ChemDiv3_012231 COc1ccc(NC(=O)CSc2nnc(C)n3c4ccsc4cc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L22 compound treatment 0.272 0.0438 0.63 0.313 0.0939 1.58 1.5573 0.9182 3036111 ChemDiv3_012232 CC(C)CN(CC(C)C)C(=O)NCc1noc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L23 mock treatment 0.221 -0.00722 -0.1 0.22 9.06E-4 0.02 -0.0623 -0.5965 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 L24 mock treatment 0.258 0.0298 0.43 0.204 -0.0151 -0.25 0.1221 0.2463 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M01 compound treatment 0.216 -0.0122 -0.17 0.248 0.0289 0.49 0.2195 0.4256 3036112 ChemDiv3_012233 O=C(CSCc1ccccc1)Nc2ccc(cc2)c3nc4cccnc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M02 compound treatment 0.278 0.0498 0.71 0.285 0.0659 1.11 1.2857 0.9773 3036114 ChemDiv3_012234 Cc1c(sc2nc3CCCCn3c(=O)c12)C(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M03 compound treatment 0.287 0.0588 0.84 0.263 0.0439 0.74 1.1156 0.9978 3036115 ChemDiv3_012235 O=C(NCC(N1CCN(Cc2ccccc2)CC1)c3cccnc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M04 compound treatment 0.254 0.0258 0.37 0.263 0.0439 0.74 0.7818 0.9488 3121228 ChemDiv3_012236 COc1cc(NC(=O)N2CCOc3ccccc23)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M05 compound treatment 0.24 0.0118 0.17 0.284 0.0649 1.09 0.8895 0.8069 3036118 ChemDiv3_012237 CC(C)CC(=O)Nc1nn2c(nnc2s1)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M06 compound treatment 0.295 0.0668 0.96 0.289 0.0699 1.17 1.5051 0.9948 3121229 ChemDiv3_012238 O=C(NC1CCCC1)c2ccc(cc2)n3c(cc4CCCCc43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M07 compound treatment 0.288 0.0598 0.86 0.3 0.0809 1.36 1.5648 0.9751 3036120 ChemDiv3_012239 CCOC(=O)c1ccccc1NC(=O)Cn2c(noc2=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M08 compound treatment 0.311 0.0828 1.18 0.28 0.0609 1.02 1.5601 0.9973 3121230 ChemDiv3_012240 CC1CCN(CC1)C(=O)c2ccc3nc(SCc4ccc(F)cc4)n(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M09 compound treatment 0.289 0.0608 0.87 0.29 0.0709 1.19 1.4563 0.9881 3121231 ChemDiv3_012241 CCOc1ccc(NC(=O)CNS(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M10 compound treatment 0.275 0.0468 0.67 0.281 0.0619 1.04 1.2079 0.9773 3036123 ChemDiv3_012242 CCCNC(=O)Cn1c(=O)c2cccn2c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M11 compound treatment 0.308 0.0798 1.14 0.274 0.0549 0.92 1.4586 0.9944 3121232 ChemDiv3_012243 Cc1ccc(cc1)n2c(=O)[nH]cc(C(=O)N3CCc4ccccc34)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M12 compound treatment 0.214 -0.0142 -0.2 0.247 0.0279 0.47 0.1874 0.367 3036125 ChemDiv3_012244 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NC4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M13 compound treatment 0.279 0.0508 0.73 0.24 0.0209 0.35 0.7617 0.9443 3121233 ChemDiv3_012245 CN(Cc1ccccc1)C(=O)c2cc(cn2C)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M14 compound treatment 0.25 0.0218 0.31 0.245 0.0259 0.43 0.5278 0.9866 3121234 ChemDiv3_012246 CCN1CCCC1CNC(=O)CCCc2cn(CC)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M15 compound treatment 0.236 0.00778 0.11 0.25 0.0309 0.52 0.4455 0.8397 3036128 ChemDiv3_012247 CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M16 compound treatment 0.277 0.0488 0.7 0.259 0.0399 0.67 0.967 0.9998 3121235 ChemDiv3_012248 COC(=O)c1ccccc1NC(=O)c2ccc3c(c2)sc4nc(cn43)c5ccc(OC)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M17 compound treatment 0.295 0.0668 0.96 0.266 0.0469 0.79 1.2321 0.9954 3036129 ChemDiv3_012249 Cc1ccccc1c2nsc(SCC(=O)NC3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M18 compound treatment 0.223 -0.00522 -0.07 0.218 -0.00109 -0.02 -0.0658 -0.8555 3121236 ChemDiv3_012250 O=C(NCC1CCCO1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M19 compound treatment 0.268 0.0398 0.57 0.278 0.0589 0.99 1.1015 0.9656 3036131 ChemDiv3_012251 CCN(CC)C(=O)Cc1noc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M20 compound treatment 0.252 0.0238 0.34 0.206 -0.0131 -0.22 0.0851 0.2102 3121237 ChemDiv3_012252 CCC(C)NC(=O)c1cc(no1)c2cccc(OC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M21 compound treatment 0.223 -0.00522 -0.07 0.239 0.0199 0.33 0.1835 0.5359 3036133 ChemDiv3_012253 Cc1nnc2c(nc3ccccc3n12)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M22 compound treatment 0.199 -0.0292 -0.42 0.202 -0.0171 -0.29 -0.4984 -0.9832 3121238 ChemDiv3_012254 CC1CC(C)N(C(C)C1)C(=O)c2cc(no2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M23 mock treatment 0.239 0.0108 0.15 0.212 -0.00709 -0.12 0.0249 0.1276 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 M24 mock treatment 0.229 7.81E-4 0.01 0.185 -0.0341 -0.57 -0.3967 -0.6932 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N01 compound treatment 0.312 0.0838 1.2 0.258 0.0389 0.65 1.3091 0.9592 3036162 ChemDiv3_012255 CCCn1cnc2c3ccccc3oc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N02 compound treatment 0.269 0.0408 0.58 0.267 0.0479 0.8 0.981 0.9876 3036164 ChemDiv3_012256 CCC(Sc1nncn2c3ccoc3cc12)C(=O)Nc4ccccc4OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N03 compound treatment 0.315 0.0868 1.24 0.313 0.0939 1.58 1.9922 0.993 3036165 ChemDiv3_012257 CCOC(=O)C(CC)n1cnc2c3ccccc3oc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N04 compound treatment 0.306 0.0778 1.11 0.329 0.11 1.84 2.0911 0.9707 3036167 ChemDiv3_012258 CCN(C(=O)CSc1nnc(CC)n2c3ccoc3cc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N05 compound treatment 0.271 0.0428 0.61 0.295 0.0759 1.27 1.3336 0.9435 3036168 ChemDiv3_012259 CC1CC(C)CN(C1)S(=O)(=O)c2cc3OCC(=O)Nc3cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N06 compound treatment 0.307 0.0788 1.13 0.323 0.104 1.74 2.03 0.9777 3036170 ChemDiv3_012260 Cc1ccc(cc1)S(=O)Cc2ccc(o2)C(=O)N3CCN(CC3)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N07 compound treatment 0.272 0.0438 0.63 0.254 0.0349 0.59 0.8571 0.9994 3036172 ChemDiv3_012261 CCOc1ccccc1N(C)S(=O)(=O)c2ccc3[nH]c(=O)ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N08 compound treatment 0.248 0.0198 0.28 0.248 0.0289 0.49 0.5431 0.967 3121239 ChemDiv3_012262 CC(C)Sc1ccc2nnc(c3ccccn3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N09 compound treatment 0.295 0.0668 0.96 0.276 0.0569 0.96 1.3508 1.0 3036173 ChemDiv3_012263 O=C(CN1C(=O)CCc2ccccc12)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N10 compound treatment 0.291 0.0628 0.9 0.315 0.0959 1.61 1.7732 0.962 3121240 ChemDiv3_012264 C(Sc1ccc(nn1)c2ccco2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N11 compound treatment 0.305 0.0768 1.1 0.279 0.0599 1.01 1.4876 0.999 3121241 ChemDiv3_012265 Cn1c(=O)n(CC=C)c(=O)c2n3CCN(c3nc12)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N12 compound treatment 0.251 0.0228 0.33 0.274 0.0549 0.92 0.882 0.9024 3036176 ChemDiv3_012266 O=C(CSc1ccc(nn1)c2cccs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N13 compound treatment 0.274 0.0458 0.65 0.25 0.0309 0.52 0.8298 0.9933 3121242 ChemDiv3_012267 CN1CCN(CC1)c2ccccc2NS(=O)(=O)c3ccc4NC(=O)CSc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N14 compound treatment 0.308 0.0798 1.14 0.32 0.101 1.69 2.0045 0.9815 3036178 ChemDiv3_012268 O=C(CSc1ccc(nn1)c2ccncc2)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N15 compound treatment 0.303 0.0748 1.07 0.244 0.0249 0.42 1.0519 0.916 3121243 ChemDiv3_012269 CN(Cc1ccccc1)S(=O)(=O)c2cc3OCCN(C)c3cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N16 compound treatment 0.284 0.0558 0.8 0.263 0.0439 0.74 1.0853 0.9992 3036180 ChemDiv3_012270 COc1ccc(cc1)c2nc(C)c(CCNS(=O)(=O)N(C)C)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N17 compound treatment 0.303 0.0748 1.07 0.29 0.0709 1.19 1.5979 0.9986 3121244 ChemDiv3_012271 CCOc1ccc(NC(=O)CCS(=O)(=O)c2ccc3NC(=O)COc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N18 compound treatment 0.273 0.0448 0.64 0.298 0.0789 1.32 1.3894 0.9444 3121245 ChemDiv3_012272 Cc1nc(sc1CCNC(=O)C(C)(C)C)c2cccc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N19 compound treatment 0.278 0.0498 0.71 0.269 0.0499 0.84 1.0958 0.9967 3036182 ChemDiv3_012273 CCc1ccccc1NC(=O)CSc2nncn3c4ccsc4cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N20 compound treatment 0.284 0.0558 0.8 0.23 0.0109 0.18 0.6936 0.8473 3121246 ChemDiv3_012274 CCCn1c(=O)n(C)c2nc3N(Cc4ccco4)CCCn3c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N21 compound treatment 0.286 0.0578 0.83 0.238 0.0189 0.32 0.8088 0.9136 3036185 ChemDiv3_012275 CCc1nnc(SCC(=O)NCc2ccc(C)cc2)c3cc4sccc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N22 compound treatment 0.26 0.0318 0.45 0.274 0.0549 0.92 0.9731 0.947 3121247 ChemDiv3_012276 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)NN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N23 mock treatment 0.234 0.00578 0.08 0.256 0.0369 0.62 0.4965 0.7945 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 N24 mock treatment 0.207 -0.0212 -0.3 0.203 -0.0161 -0.27 -0.4056 -0.9983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O01 compound treatment 0.244 0.0158 0.23 0.24 0.0209 0.35 0.4077 0.9772 3121248 ChemDiv3_012277 O=C(Cc1ccccc1)Nc2ccc(cc2)c3nc4cccnc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O02 compound treatment 0.265 0.0368 0.53 0.25 0.0309 0.52 0.7388 1.0 3036187 ChemDiv3_012278 CC1CN(CCN1c2ccc(C)cc2)C(=O)c3sc4nc5CCCCn5c(=O)c4c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O03 compound treatment 0.26 0.0318 0.45 0.276 0.0569 0.96 0.9968 0.9424 3121249 ChemDiv3_012279 CC(C)(C)C(=O)NCC(N1CCN(CC1)c2ccccc2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O04 compound treatment 0.247 0.0188 0.27 0.26 0.0409 0.69 0.6754 0.9161 3036224 ChemDiv3_012280 CCOc1ccccc1NC(=O)N2CCOc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O05 compound treatment 0.282 0.0538 0.77 0.292 0.0729 1.22 1.4092 0.975 3036226 ChemDiv3_012281 Cc1[nH]c(cc1C(=O)NC2CCCCC2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O06 compound treatment 0.234 0.00578 0.08 0.267 0.0479 0.8 0.627 0.7757 3036227 ChemDiv3_012282 CCCNC(=O)c1ccc(cc1)n2c(cc3CCCCc32)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O07 compound treatment 0.262 0.0338 0.48 0.249 0.0299 0.5 0.6966 0.9998 3036229 ChemDiv3_012283 FC(F)(F)c1ccccc1NC(=O)CSc2nc3nccnc3c(=O)n2Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O08 compound treatment 0.262 0.0338 0.48 0.205 -0.0141 -0.24 0.1744 0.3242 3036230 ChemDiv3_012284 Cc1ccc(CSc2nc3ccc(cc3n2C)C(=O)N4CCN(CC4)c5ccccc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O09 compound treatment 0.23 0.00178 0.03 0.235 0.0159 0.27 0.2068 0.7711 3036232 ChemDiv3_012285 CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O10 compound treatment 0.226 -0.00222 -0.03 0.235 0.0159 0.27 0.1663 0.6187 3036233 ChemDiv3_012286 Cc1cc(C)cc(NC(=O)Cn2c(=O)c3cccn3c4ccccc24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O11 compound treatment 0.217 -0.0112 -0.16 0.235 0.0159 0.27 0.0753 0.2418 3121250 ChemDiv3_012287 CCOc1ccc(cc1)n2c(=O)[nH]cc(C(=O)N3CCCc4ccccc34)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O12 compound treatment 0.292 0.0638 0.91 0.248 0.0289 0.49 0.9882 0.9563 3121251 ChemDiv3_012288 CCC(C)NC(=O)C1CCN(CC1)c2nc3ccccc3n4cccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O13 compound treatment 0.272 0.0438 0.63 0.245 0.0259 0.43 0.7503 0.9841 3036236 ChemDiv3_012289 CCCN(CCC)C(=O)c1cc(cn1C)S(=O)(=O)N2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O14 compound treatment 0.251 0.0228 0.33 0.247 0.0279 0.47 0.5616 0.9843 3036290 ChemDiv3_012290 CCn1cc(CCCC(=O)NCCC2=CCCCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O15 compound treatment 0.225 -0.00322 -0.05 0.224 0.00491 0.08 0.0257 0.2721 3121252 ChemDiv3_012291 Cc1ccc(cc1)c2nsc(SCC(=O)N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O16 compound treatment 0.196 -0.0322 -0.46 0.184 -0.0351 -0.59 -0.7424 -0.9926 3036238 ChemDiv3_012292 CCNC(=O)c1ccc2c(c1)sc3nc(cn32)c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O17 compound treatment 0.244 0.0158 0.23 0.222 0.00291 0.05 0.1941 0.8405 3121253 ChemDiv3_012293 NC(=O)CSc1nc(ns1)c2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O18 compound treatment 0.208 -0.0202 -0.29 0.194 -0.0251 -0.42 -0.5023 -0.9832 3121254 ChemDiv3_012294 O=C(NCCC1=CCCCC1)c2ccc3c(c2)sc4nc(cn43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O19 compound treatment 0.233 0.00478 0.07 0.224 0.00491 0.08 0.1066 0.9957 3036241 ChemDiv3_012295 CN(C(=O)Cc1noc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O20 compound treatment 0.27 0.0418 0.6 0.216 -0.00309 -0.05 0.3859 0.6432 3121429 ChemDiv3_012296 COc1cccc(c1)c2cc(on2)C(=O)N3CCN(CC3)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O21 compound treatment 0.215 -0.0132 -0.19 0.202 -0.0171 -0.29 -0.3366 -0.9795 3036243 ChemDiv3_012297 CNc1nc2ccccc2n3c(C)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O22 compound treatment 0.247 0.0188 0.27 0.219 -9.38E-5 0.0 0.1888 0.703 3121430 ChemDiv3_012298 Fc1ccc(cc1)c2cc(on2)C(=O)N3CCN(CC3)c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O23 mock treatment 0.215 -0.0132 -0.19 0.221 0.00191 0.03 -0.1111 -0.5792 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 O24 mock treatment 0.212 -0.0162 -0.23 0.182 -0.0371 -0.62 -0.6043 -0.9095 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P01 compound treatment 0.26 0.0318 0.45 0.244 0.0249 0.42 0.617 0.9991 3036246 ChemDiv3_012299 C=CCn1cnc2c3ccccc3oc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P02 compound treatment 0.255 0.0268 0.38 0.258 0.0389 0.65 0.7326 0.9677 3121431 ChemDiv3_012300 COc1ccccc1NC(=O)CSc2nncn3c4cc(C)oc4cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P03 compound treatment 0.271 0.0428 0.61 0.237 0.0179 0.3 0.6452 0.9464 3036247 ChemDiv3_012301 COc1ccc(NS(=O)(=O)c2ccc3NC(=O)COc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P04 compound treatment 0.311 0.0828 1.18 0.319 0.0999 1.68 2.023 0.9855 3121432 ChemDiv3_012302 CCc1nnc(SCc2ccccc2)c3cc4occc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P05 compound treatment 0.309 0.0808 1.16 0.281 0.0619 1.04 1.5517 0.9986 3121433 ChemDiv3_012303 CC1CCCC(NS(=O)(=O)c2cc3OCC(=O)Nc3cc2C)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P06 compound treatment 0.291 0.0628 0.9 0.284 0.0649 1.09 1.4053 0.9954 3036250 ChemDiv3_012304 Cc1ccc(CS(=O)Cc2ccc(o2)C(=O)N3CCN(Cc4ccccc4)CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P07 compound treatment 0.265 0.0368 0.53 0.265 0.0459 0.77 0.9168 0.9827 3121434 ChemDiv3_012305 Clc1cccc(c1)N2CCN(CCNS(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P08 compound treatment 0.321 0.0928 1.33 0.251 0.0319 0.54 1.3171 0.9203 3036291 ChemDiv3_012306 CCc1ccc(NC(=O)CSc2ccc3nnc(c4ccccn4)n3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P09 compound treatment 0.243 0.0148 0.21 0.273 0.0539 0.9 0.7893 0.8495 3036293 ChemDiv3_012307 COc1ccc(cc1)n2cc(C(=O)NCCN3CCc4ccccc4C3)c5ccccc5c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P10 compound treatment 0.297 0.0688 0.98 0.262 0.0429 0.72 1.2049 0.9882 3036294 ChemDiv3_012308 NC(=O)CSc1ccc(nn1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P11 compound treatment 0.245 0.0168 0.24 0.261 0.0419 0.7 0.6671 0.8976 3036296 ChemDiv3_012309 O=C1CSc2cc(ccc2N1)S(=O)(=O)NN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P12 compound treatment 0.289 0.0608 0.87 0.279 0.0599 1.01 1.3257 0.9974 3036297 ChemDiv3_012310 COc1ccccc1CCNC(=O)CSc2ccc(nn2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P13 compound treatment 0.257 0.0288 0.41 0.243 0.0239 0.4 0.5748 0.9999 3121435 ChemDiv3_012311 CCc1ccc(NS(=O)(=O)c2ccc3NC(=O)C(C)Sc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P14 compound treatment 0.218 -0.0102 -0.15 0.234 0.0149 0.25 0.0736 0.2538 3036299 ChemDiv3_012312 Fc1ccc(cc1)C(=O)CSc2ccc(nn2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P15 compound treatment 0.247 0.0188 0.27 0.258 0.0389 0.65 0.6517 0.923 3036301 ChemDiv3_012313 CN1CCOc2cc(c(C)cc12)S(=O)(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P16 compound treatment 0.262 0.0338 0.48 0.234 0.0149 0.25 0.5186 0.9531 3121436 ChemDiv3_012314 Cc1nc(sc1CCNS(=O)(=O)c2ccc(F)c(c2)C(F)(F)F)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P17 compound treatment 0.298 0.0698 1.0 0.263 0.0439 0.74 1.2269 0.9889 3121437 ChemDiv3_012315 O=C(NC1CCCC1)C2CCN(CC2)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P18 compound treatment 0.187 -0.0412 -0.59 0.263 0.0439 0.74 0.1042 0.1104 3036304 ChemDiv3_012316 COc1ccc(cc1)C(=O)NCCc2sc(nc2C)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P19 compound treatment 0.258 0.0298 0.43 0.254 0.0349 0.59 0.7155 0.9877 3121438 ChemDiv3_012317 CSc1cccc(NC(=O)CSc2nncn3c4ccsc4cc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P20 compound treatment 0.242 0.0138 0.2 0.234 0.0149 0.25 0.3163 0.993 3036306 ChemDiv3_012318 Cn1c(=O)n(CC=C)c(=O)c2n3CCCN(C4CCCCC4)c3nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P21 compound treatment 0.287 0.0588 0.84 0.235 0.0159 0.27 0.7833 0.8879 3121439 ChemDiv3_012319 CCC(Sc1nnc(CC)n2c3ccsc3cc12)C(=O)NCc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P22 compound treatment 0.254 0.0258 0.37 0.267 0.0479 0.8 0.8293 0.9375 3121440 ChemDiv3_012320 CCc1ccccc1NS(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P23 mock treatment 0.207 -0.0212 -0.3 0.231 0.0119 0.2 -0.0733 -0.2017 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2035 P24 mock treatment 0.214 -0.0142 -0.2 0.198 -0.0211 -0.35 -0.3942 -0.9654 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A01 compound treatment 0.247 0.0232 0.33 0.217 -0.00422 -0.07 0.1845 0.5439 3036308 ChemDiv3_012321 CCC(Cc1ccccc1)NS(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A02 compound treatment 0.251 0.0272 0.39 0.223 0.00178 0.03 0.2961 0.7592 3121441 ChemDiv3_012322 O=C/1OC(=N\C1=C/c2ccco2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A03 compound treatment 0.29 0.0662 0.95 0.264 0.0428 0.72 1.1772 0.9907 3121442 ChemDiv3_012323 Cc1cc(C)cc(c1)n2c(SCC(=O)Nc3ccccc3C(F)(F)F)nc4CCSc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A04 compound treatment 0.191 -0.0328 -0.47 0.173 -0.0482 -0.81 -0.9041 -0.9664 3036310 ChemDiv3_012324 O=C/1OC(=N\C1=C\NC2CCCCC2)c3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A05 compound treatment 0.245 0.0212 0.3 0.246 0.0248 0.42 0.5084 0.9879 3121443 ChemDiv3_012325 O=C(Cn1cc(SCc2ccccc2)c3ccccc13)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A06 compound treatment 0.218 -0.00581 -0.08 0.244 0.0228 0.38 0.2116 0.5407 3036312 ChemDiv3_012326 CC(=O)Nc1ccccc1/C(=N/C2CCCCC2)/C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A07 compound treatment 0.245 0.0212 0.3 0.244 0.0228 0.38 0.4847 0.9934 3121444 ChemDiv3_012327 CCN(CC)C(=O)Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)NCc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A08 compound treatment 0.268 0.0442 0.63 0.238 0.0168 0.28 0.6461 0.9337 3121445 ChemDiv3_012328 CCOc1cccc2cc(C(=O)Nc3nccs3)/c(=N/c4cccc(c4)C(F)(F)F)/oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A09 compound treatment 0.281 0.0572 0.82 0.256 0.0348 0.58 0.9912 0.9863 3036314 ChemDiv3_012329 CCc1ccc(NC(=O)N2CC(C)Sc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A10 compound treatment 0.277 0.0532 0.76 0.22 -0.00122 -0.02 0.5235 0.6878 3121446 ChemDiv3_012330 O=C(N1CCN(CC1)c2ccccc2)c3ccc(Cn4c(=O)[nH]c5ccccc5c4=O)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A11 compound treatment 0.248 0.0242 0.35 0.244 0.0228 0.38 0.515 0.9988 3036316 ChemDiv3_012331 CCc1ccc2nc(sc2c1)N(CCN(C)C)C(=O)C3COc4ccccc4O3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A12 compound treatment 0.27 0.0462 0.66 0.254 0.0328 0.55 0.8562 0.9959 3121447 ChemDiv3_012332 CCC(=O)c1cc2ccccc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A13 compound treatment 0.23 0.00619 0.09 0.218 -0.00322 -0.05 0.0244 0.2351 3121448 ChemDiv3_012333 Clc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A14 compound treatment 0.206 -0.0178 -0.25 0.233 0.0118 0.2 -0.0403 -0.1251 1630757 ChemDiv3_012334 COc1cccc(Nc2nnc(s2)c3cc4cccc(OC)c4oc3=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A15 compound treatment 0.235 0.0112 0.16 0.234 0.0128 0.21 0.2648 0.9896 3036368 ChemDiv3_012335 O=C(NCCc1csc2nc(nn12)c3ccccc3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A16 compound treatment 0.1 -0.124 -1.77 0.105 -0.116 -1.95 -2.6316 -0.9988 3036369 ChemDiv3_012336 O=C(NCc1ccc2OCOc2c1)c3sc(=S)n4c3[nH]c(=O)c5ccccc54 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A17 compound treatment 0.257 0.0332 0.47 0.222 7.81E-4 0.01 0.3449 0.7264 3036371 ChemDiv3_012337 COc1ccc(/C=N/c2ccc(cc2)C3(CC4CC5CC(C4)C3)C5)c(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A18 compound treatment 0.21 -0.0138 -0.2 0.218 -0.00322 -0.05 -0.1779 -0.8686 3036372 ChemDiv3_012338 Nc1c(nnn1c2ccc(OC(F)(F)F)cc2)C(=O)NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A19 compound treatment 0.212 -0.0118 -0.17 0.221 -2.19E-4 0.0 -0.1221 -0.7223 3036374 ChemDiv3_012339 Cc1cc(N/C(=N\S(=O)(=O)c2ccc(C)cc2)/c3ccccc3)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A20 compound treatment 0.228 0.00419 0.06 0.216 -0.00522 -0.09 -0.0196 -0.1846 3036375 ChemDiv3_012340 CSc1nc(cn1c2cccc(Cl)c2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A21 compound treatment 0.254 0.0302 0.43 0.23 0.00878 0.15 0.4095 0.8976 3036377 ChemDiv3_012341 CC(C)(C)c1ccc(/C=N/n2cnnc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A22 compound treatment 0.237 0.0132 0.19 0.24 0.0188 0.32 0.3563 0.9699 3121449 ChemDiv3_012342 CCC(C)NC(=O)c1ccc(NC2=NC3CS(=O)(=O)CC3S2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A23 mock treatment 0.228 0.00419 0.06 0.218 -0.00322 -0.05 0.0042 0.0515 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 A24 mock treatment 0.218 -0.00581 -0.08 0.21 -0.0112 -0.19 -0.1919 -0.9325 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B01 compound treatment 0.22 -0.00381 -0.05 0.243 0.0218 0.37 0.2199 0.595 3121450 ChemDiv3_012343 CCC(Sc1nc2ccccc2c3nc4ccccc4n13)C(=O)N5CCOCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B02 compound treatment 0.265 0.0412 0.59 0.257 0.0358 0.6 0.8412 1.0 3036379 ChemDiv3_012344 Fc1ccccc1CSC2=Nc3ccccc3C4=NC(CC(=O)NC5CCCCC5)C(=O)N42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B03 compound treatment 0.256 0.0322 0.46 0.26 0.0388 0.65 0.7858 0.9856 1528378 ChemDiv3_012345 Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B04 compound treatment 0.254 0.0302 0.43 0.252 0.0308 0.52 0.6706 0.996 1456817 ChemDiv3_012346 COC(=O)c1ccc2c(=O)n(c(SCC(=O)C(C)(C)C)nc2c1)c3ccc(F)c(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B05 compound treatment 0.283 0.0592 0.85 0.275 0.0538 0.9 1.2369 0.9995 3036381 ChemDiv3_012347 CC(CC(=O)NC1CCCCCC1)CC2=Nc3ccccc3S(=O)(=O)N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B06 compound treatment 0.272 0.0482 0.69 0.275 0.0538 0.9 1.1257 0.9911 1665762 ChemDiv3_012348 O=C(CSc1nc2ccccc2c(=O)n1CCc3ccccc3)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B07 compound treatment 0.274 0.0502 0.72 0.251 0.0298 0.5 0.8611 0.9843 3036383 ChemDiv3_012349 Cc1cccc(NC2=Nc3ccccc3S(=O)(=O)N2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B08 compound treatment 0.246 0.0222 0.32 0.248 0.0268 0.45 0.5423 0.9855 1562044 ChemDiv3_012350 CCOC(=O)c1cc(CSc2nc3ccccc3c(=O)n2Cc4cccs4)c5OCOCc5c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B09 compound treatment 0.267 0.0432 0.62 0.259 0.0378 0.63 0.8852 0.9999 3121451 ChemDiv3_012351 O=C(CSc1nc2c3ccccc3sc2c(=O)n1Cc4ccccc4)NCCC5=CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B10 compound treatment 0.265 0.0412 0.59 0.259 0.0378 0.63 0.865 0.9993 1694421 ChemDiv3_012352 O=C(NC1CCCCC1)C2CCC(Cn3c(=O)c4ccccc4[nH]c3=S)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B11 compound treatment 0.271 0.0472 0.67 0.264 0.0428 0.72 0.985 0.9995 3121627 ChemDiv3_012353 O=c1n(CCCN2CCOCC2)c(SCC#N)nc3c4ccccc4sc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B12 compound treatment 0.271 0.0472 0.67 0.243 0.0218 0.37 0.7358 0.9585 1139359 ChemDiv3_012354 CC(=O)NCCn1c(SCC(=O)NCc2ccccc2)nc3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B13 compound treatment 0.241 0.0172 0.25 0.219 -0.00222 -0.04 0.1475 0.5932 3121628 ChemDiv3_012355 C=CCN(C(=O)CSc1nc2c3ccccc3sc2c(=O)n1Cc4cccnc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B14 compound treatment 0.283 0.0592 0.85 0.266 0.0448 0.75 1.1301 0.9982 1712288 ChemDiv3_012356 O=C(CCn1c(SCC(=O)c2ccccc2)nc3ccccc3c1=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B15 compound treatment 0.253 0.0292 0.42 0.252 0.0308 0.52 0.6605 0.9944 3036389 ChemDiv3_012357 CN(C)C(=O)C1C2NC(=S)N(c3cccc(C)c3)C1(C)Oc4c(Cl)cc(Cl)cc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B16 compound treatment 0.284 0.0602 0.86 0.271 0.0498 0.84 1.1996 0.9999 1243347 ChemDiv3_012358 O=C(CCCn1c(SCC#N)nc2ccccc2c1=O)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B17 compound treatment 0.274 0.0502 0.72 0.251 0.0298 0.5 0.8611 0.9843 3121629 ChemDiv3_012359 COc1ccc2C3C(C(=O)c4ccccc4)C(=O)NC5(CCCCC35)Oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B18 compound treatment 0.218 -0.00581 -0.08 0.235 0.0138 0.23 0.1048 0.4262 1732946 ChemDiv3_012360 CCOC(=O)N1CCN(CC1)C(=O)CCCn2c(=O)c3cc(Br)ccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B19 compound treatment 0.241 0.0172 0.25 0.274 0.0528 0.89 0.8003 0.8704 3121630 ChemDiv3_012361 CCC(SC1=Nc2ccccc2C3=NC(CC(C)C)C(=O)N31)C(=O)Nc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B20 compound treatment 0.26 0.0362 0.52 0.28 0.0588 0.99 1.0636 0.9547 1372747 ChemDiv3_012362 CCOC(CCn1c(SCc2cccc(F)c2)nc3ccccc3c1=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B21 compound treatment 0.277 0.0532 0.76 0.271 0.0498 0.84 1.1288 0.9989 3036435 ChemDiv3_012363 CC1N=C2N(C1=O)C(=Nc3ccccc23)SCc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B22 compound treatment 0.22 -0.00381 -0.05 0.235 0.0138 0.23 0.125 0.526 3036437 ChemDiv3_012364 COc1cc2[nH]c(=S)n(C3CC3)c(=O)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B23 mock treatment 0.239 0.0152 0.22 0.252 0.0308 0.52 0.5189 0.9259 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 B24 mock treatment 0.229 0.00519 0.07 0.237 0.0158 0.26 0.2398 0.8716 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C01 compound treatment 0.253 0.0292 0.42 0.229 0.00778 0.13 0.3876 0.886 3036438 ChemDiv3_012365 CCN(c1ccc(OC)cc1)S(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C02 compound treatment 0.252 0.0282 0.4 0.24 0.0188 0.32 0.508 0.9926 3036440 ChemDiv3_012366 CC(=O)Oc1cccc(/C=C/2\N=C(OC2=O)c3ccccc3Br)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C03 compound treatment 0.255 0.0312 0.45 0.254 0.0328 0.55 0.7045 0.9946 3036441 ChemDiv3_012367 Cc1cc(C)cc(c1)n2c(SCC(=O)NCc3ccc(F)cc3)nc4CCSc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C04 compound treatment 0.235 0.0112 0.16 0.045 -0.176 -2.96 -1.9782 -0.6679 3036443 ChemDiv3_012368 O=C/1OC(=N\C1=C/Nc2ccc3ccccc3c2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C05 compound treatment 0.039 -0.185 -2.64 0.04 -0.181 -3.04 -4.02 -0.9976 3121631 ChemDiv3_012369 O=C(CSc1cn(CC(=O)N2CCOCC2)c3ccccc13)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C06 compound treatment 0.269 0.0452 0.65 0.27 0.0488 0.82 1.036 0.9931 3036445 ChemDiv3_012370 COc1ccc(cc1)c2nc3cc(F)c(Cl)cc3nc2c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C07 compound treatment 0.261 0.0372 0.53 0.04 -0.181 -3.04 -1.7746 -0.5747 3121632 ChemDiv3_012371 CNC(=O)CS(=O)(=O)c1cn(CC(=O)N2CCCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C08 compound treatment 0.268 0.0442 0.63 0.237 0.0158 0.26 0.6342 0.9255 3121633 ChemDiv3_012372 CCOc1cccc2cc(C(=O)Nc3nccs3)/c(=N/c4ccc(C)c(C)c4)/oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C09 compound treatment 0.238 0.0142 0.2 0.21 -0.0112 -0.19 0.0104 0.0374 3036448 ChemDiv3_012373 CC1CN(C(=O)Nc2cccc(Cl)c2C)c3ccccc3S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C10 compound treatment 0.256 0.0322 0.46 0.242 0.0208 0.35 0.5722 0.9906 3121634 ChemDiv3_012374 CCOc1cc2[nH]c(=O)n(Cc3cccc(OC)c3)c(=O)c2cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C11 compound treatment 0.253 0.0292 0.42 0.282 0.0608 1.02 1.0166 0.9222 3036450 ChemDiv3_012375 CN(C)CCN(C(=O)c1ccc2ncsc2c1)c3nc4c(C)cccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C12 compound treatment 0.298 0.0742 1.06 0.285 0.0638 1.07 1.5073 1.0 1011589 ChemDiv3_012376 O=C(c1ccccc1)c2cc3ccccc3oc2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C13 compound treatment 0.265 0.0412 0.59 0.243 0.0218 0.37 0.6751 0.9737 3121635 ChemDiv3_012377 Clc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)N3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C14 compound treatment 0.274 0.0502 0.72 0.247 0.0258 0.43 0.8136 0.9706 3036453 ChemDiv3_012378 COc1ccc2oc(=O)c(cc2c1)c3nnc(NCc4ccc5OCOc5c4)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C15 compound treatment 0.052 -0.172 -2.46 0.061 -0.16 -2.69 -3.6392 -0.999 3121636 ChemDiv3_012379 CC1CN(CC(C)O1)c2nc(Nc3ccc(C)c(Cl)c3)c4cnn(C)c4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C16 compound treatment 0.242 0.0182 0.26 0.239 0.0178 0.3 0.395 0.9977 3036455 ChemDiv3_012380 CC(C)NC(=O)c1sc(=S)n2c1[nH]c(=O)c3ccc(cc32)C(=O)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C17 compound treatment 0.212 -0.0118 -0.17 0.176 -0.0452 -0.76 -0.6561 -0.8439 3121637 ChemDiv3_012381 FC(F)(F)c1ccc(Cl)c(NC(=O)CC(=O)c2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C18 compound treatment 0.089 -0.135 -1.93 0.067 -0.154 -2.59 -3.1938 -0.9895 1593078 ChemDiv3_012382 S=c1[nH]c(cn1c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C19 compound treatment 0.244 0.0202 0.29 0.212 -0.00922 -0.15 0.0948 0.2893 3121638 ChemDiv3_012383 FC(F)(F)c1cccc(/C=N/n2cnnc2SCc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C20 compound treatment 0.24 0.0162 0.23 0.221 -2.19E-4 0.0 0.1611 0.6958 3121639 ChemDiv3_012384 Cc1ccc(cc1)n2cc(nc2SCC(=O)NCCc3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C21 compound treatment 0.264 0.0402 0.57 0.21 -0.0112 -0.19 0.2733 0.4519 3036458 ChemDiv3_012385 COc1ccc(/C=N/N(C)C2=NCCN2)c(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C22 compound treatment 0.228 0.00419 0.06 0.235 0.0138 0.23 0.2059 0.8618 3121640 ChemDiv3_012386 FC(F)(F)c1cccc(OCCNC(=O)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C23 mock treatment 0.246 0.0222 0.32 0.22 -0.00122 -0.02 0.2099 0.6602 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 C24 mock treatment 0.233 0.00919 0.13 0.208 -0.0132 -0.22 -0.064 -0.248 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D01 compound treatment 0.292 0.0682 0.98 0.265 0.0438 0.73 1.2093 0.9903 3036460 ChemDiv3_012387 Cn1c(=O)c2nc(oc2c3ccccc13)c4ccccc4I 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D02 compound treatment 0.245 0.0212 0.3 0.235 0.0138 0.23 0.3779 0.9911 3036503 ChemDiv3_012388 O=C(CC1N=C2N(C1=O)C(=Nc3ccccc23)SCC(=O)c4ccccc4)NCCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D03 compound treatment 0.269 0.0452 0.65 0.247 0.0258 0.43 0.763 0.981 3036504 ChemDiv3_012389 O=C(CCCC1=Nc2ccccc2S(=O)(=O)N1)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D04 compound treatment 0.295 0.0712 1.02 0.301 0.0798 1.34 1.6669 0.9909 1076056 ChemDiv3_012390 CCCCn1c(=O)c2ccccc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D05 compound treatment 0.286 0.0622 0.89 0.333 0.112 1.88 1.9556 0.9419 3036506 ChemDiv3_012391 Cc1cccc(N2CCN(CC2)C(=O)CC3(CC4=Nc5ccccc5S(=O)(=O)N4)CCCC3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D06 compound treatment 0.279 0.0552 0.79 0.294 0.0728 1.22 1.422 0.9777 1698753 ChemDiv3_012392 Clc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2CCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D07 compound treatment 0.28 0.0562 0.8 0.263 0.0418 0.7 1.0642 0.9977 3036508 ChemDiv3_012393 COC(=O)c1ccccc1n2c(N)c(C#N)c(N)c(C#N)c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D08 compound treatment 0.282 0.0582 0.83 0.253 0.0318 0.53 0.9657 0.9769 1613927 ChemDiv3_012394 Clc1ccc(CSc2nc3ccccc3c(=O)n2Cc4cccs4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D09 compound treatment 0.264 0.0402 0.57 0.307 0.0858 1.44 1.4245 0.9189 3121641 ChemDiv3_012395 COc1ccc(CCn2c(=O)c3sc4ccccc4c3[nH]c2=S)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D10 compound treatment 0.267 0.0432 0.62 0.264 0.0428 0.72 0.9445 0.9972 1185287 ChemDiv3_012396 COC(=O)c1ccc2c(=O)n(CC3CCCO3)c(SCC(=O)Nc4ccccc4Cl)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D11 compound treatment 0.298 0.0742 1.06 0.282 0.0608 1.02 1.4717 0.9998 3036510 ChemDiv3_012397 COc1ccc(CCNC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CCO)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D12 compound treatment 0.293 0.0692 0.99 0.306 0.0848 1.42 1.706 0.9842 1434889 ChemDiv3_012398 COc1ccc(NC(=O)CCCn2c(=O)c3ccccc3[nH]c2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D13 compound treatment 0.274 0.0502 0.72 0.258 0.0368 0.62 0.9441 0.9972 3036513 ChemDiv3_012399 Cc1ccccc1Nc2sc(C(=O)c3ccccc3)c(N)c2C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D14 compound treatment 0.242 0.0182 0.26 0.263 0.0418 0.7 0.6798 0.9089 1547109 ChemDiv3_012400 O=C(CC#N)Nn1c(=O)c2ccccc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D15 compound treatment 0.293 0.0692 0.99 0.278 0.0568 0.95 1.3737 0.9998 3121642 ChemDiv3_012401 COc1cccc2C3NC(=S)NC(C)(Oc12)C3C(=O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D16 compound treatment 0.282 0.0582 0.83 0.306 0.0848 1.42 1.5947 0.9674 1155487 ChemDiv3_012402 Fc1cccc(CSc2nc3ccccc3c(=O)n2CCC(=O)NCCc4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D17 compound treatment 0.312 0.0882 1.26 0.32 0.0988 1.66 2.0643 0.9909 3121643 ChemDiv3_012403 COc1ccccc1C(=O)C2C3CC(C)(NC2=O)Oc4ccc(Cl)cc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D18 compound treatment 0.319 0.0952 1.36 0.29 0.0688 1.15 1.7791 0.9966 1421160 ChemDiv3_012404 CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCCC(=O)N4CCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D19 compound treatment 0.307 0.0832 1.19 0.313 0.0918 1.54 1.9306 0.9919 3036517 ChemDiv3_012405 CCC(C)C1N=C2N(C1=O)C(=Nc3ccccc23)SCc4cc(=O)n5ccccc5n4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D20 compound treatment 0.275 0.0512 0.73 0.283 0.0618 1.04 1.2509 0.9855 3121644 ChemDiv3_012406 Clc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D21 compound treatment 0.275 0.0512 0.73 0.268 0.0468 0.79 1.0729 0.9994 3121645 ChemDiv3_012407 O=C(CCC1N=C2N(C1=O)C(=S)Nc3ccccc23)N4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D22 compound treatment 0.304 0.0802 1.15 0.257 0.0358 0.6 1.2357 0.9544 3036519 ChemDiv3_012408 CC1CCN(CC1)C(=O)CSc2nc3cc4OCOc4cc3c(=O)n2CCC5=CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D23 mock treatment 0.261 0.0372 0.53 0.221 -2.19E-4 0.0 0.3735 0.7022 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 D24 mock treatment 0.239 0.0152 0.22 0.219 -0.00222 -0.04 0.1273 0.5775 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E01 compound treatment 0.214 -0.00981 -0.14 0.251 0.0298 0.5 0.2542 0.4896 3121646 ChemDiv3_012409 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N(C)CC(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E02 compound treatment 0.248 0.0242 0.35 0.221 -2.19E-4 0.0 0.242 0.6996 1660760 ChemDiv3_012410 CCOc1ncccc1C(=O)Nc2cccc(c2)C(=O)Nc3cccc(c3)S(=O)(=O)CCO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E03 compound treatment 0.254 0.0302 0.43 0.251 0.0298 0.5 0.6588 0.9973 3121828 ChemDiv3_012411 COc1cccc(c1)n2c(SCC(=O)NC3CCCC3)nc4CCSc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E04 compound treatment 0.273 0.0492 0.7 0.269 0.0478 0.8 1.0646 0.9979 3121829 ChemDiv3_012412 Cc1ccc(cc1)C2=N/C(=C/Nc3ccccc3)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E05 compound treatment 0.294 0.0702 1.0 0.321 0.0998 1.67 1.8941 0.97 3036522 ChemDiv3_012413 NC(=O)CSc1cn(CC(=O)N2CCOCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E06 compound treatment 0.242 0.0182 0.26 0.302 0.0808 1.36 1.1427 0.8277 3121830 ChemDiv3_012414 O=C(NCCc1ccccc1)c2ccc3nc(c4cccs4)c(nc3c2)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E07 compound treatment 0.245 0.0212 0.3 0.248 0.0268 0.45 0.5321 0.9816 3036524 ChemDiv3_012415 CN(C(=O)CS(=O)(=O)c1cn(CC(=O)N2CCOCC2)c3ccccc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E08 compound treatment 0.221 -0.00281 -0.04 0.128 -0.0932 -1.56 -1.1348 -0.725 3121831 ChemDiv3_012416 COc1ccc2o/c(=N\c3ccc(cc3)C(=O)O)/c(cc2c1)C(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E09 compound treatment 0.242 0.0182 0.26 0.284 0.0628 1.05 0.929 0.856 3036578 ChemDiv3_012417 FC(F)(F)c1cccc(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E10 compound treatment 0.312 0.0882 1.26 0.249 0.0278 0.47 1.2217 0.9084 3036580 ChemDiv3_012418 COc1ccc(NC(=O)CCn2c(=O)[nH]c3ccccc3c2=O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E11 compound treatment 0.295 0.0712 1.02 0.262 0.0408 0.68 1.204 0.9813 3036582 ChemDiv3_012419 CN(C)CCN(C(=O)c1ccco1)c2nc3cc4OCOc4cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E12 compound treatment 0.269 0.0452 0.65 0.24 0.0188 0.32 0.6799 0.9455 3036583 ChemDiv3_012420 CCCC(=O)c1cc2cc(Cl)ccc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E13 compound treatment 0.272 0.0482 0.69 0.265 0.0438 0.73 1.007 0.9995 3036585 ChemDiv3_012421 COc1ccc(NC(=O)c2cncc(NS(=O)(=O)c3ccc(C)cc3)c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E14 compound treatment 0.273 0.0492 0.7 0.19 -0.0312 -0.52 0.127 0.1448 1332200 ChemDiv3_012422 CC1CCC(CC1)NC(=O)CCC(=O)Nc2nc(cs2)c3cc4ccccc4oc3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E15 compound treatment 0.29 0.0662 0.95 0.262 0.0408 0.68 1.1534 0.9873 3121832 ChemDiv3_012423 COc1ccc(Nc2nc(NCCN3CCOCC3)nc4n(C)ncc24)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E16 compound treatment 0.13 -0.0938 -1.34 0.122 -0.0992 -1.67 -2.1264 -0.9943 3036587 ChemDiv3_012424 Cc1ccc(cc1)S(=O)(=O)c2nnn3c2[nH]c(=O)c4ccccc43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E17 compound treatment 0.263 0.0392 0.56 0.288 0.0668 1.12 1.1889 0.9487 1438027 ChemDiv3_012425 Cc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E18 compound treatment 0.276 0.0522 0.75 0.253 0.0318 0.53 0.905 0.9864 3036589 ChemDiv3_012426 CC(C)(C)c1cn(c2ccc(F)cc2)c(=S)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E19 compound treatment 0.216 -0.00781 -0.11 0.266 0.0448 0.75 0.4525 0.5954 3121833 ChemDiv3_012427 Brc1ccc(/C=N/n2cnnc2SCc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E20 compound treatment 0.177 -0.0468 -0.67 0.207 -0.0142 -0.24 -0.6422 -0.9035 3121834 ChemDiv3_012428 COc1ccc(OC)c(c1)n2cc(nc2SC)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E21 compound treatment 0.235 0.0112 0.16 0.247 0.0258 0.43 0.4191 0.9085 3036591 ChemDiv3_012429 CN(/N=C/c1ccncc1)C2=NCCN2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E22 compound treatment 0.277 0.0532 0.76 0.242 0.0208 0.35 0.7846 0.9375 3121835 ChemDiv3_012430 Fc1cccc(CSc2nc3ccccc3c4nc5ccccc5n24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E23 mock treatment 0.246 0.0222 0.32 0.233 0.0118 0.2 0.3642 0.9741 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 E24 mock treatment 0.237 0.0132 0.19 0.205 -0.0162 -0.27 -0.0591 -0.1785 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F01 compound treatment 0.214 -0.00981 -0.14 0.271 0.0498 0.84 0.4916 0.5802 3121836 ChemDiv3_012431 COc1ccccc1NC(=O)c2sc3nc([nH]c(=O)c3c2C)c4cc5cccc(OC)c5oc4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F02 compound treatment 0.233 0.00919 0.13 0.215 -0.00622 -0.1 0.0191 0.1139 3036593 ChemDiv3_012432 Cc1cc(C)n(CCc2nc3c4ccccc4[nH]c(=S)n3n2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F03 compound treatment 0.293 0.0692 0.99 0.301 0.0798 1.34 1.6466 0.9889 3036595 ChemDiv3_012433 O=C(CCC1=Nc2ccccc2S(=O)(=O)N1)NC3CCCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F04 compound treatment 0.289 0.0652 0.93 0.312 0.0908 1.52 1.7367 0.9722 1258951 ChemDiv3_012434 COC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(SCc4ccc(Cl)cc4)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F05 compound treatment 0.336 0.112 1.6 0.311 0.0898 1.51 2.2002 0.9995 3121837 ChemDiv3_012435 Cc1cc(C)cc(NC(=O)CN2C=NS(=O)(=O)c3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F06 compound treatment 0.289 0.0652 0.93 0.315 0.0938 1.57 1.7723 0.9688 1505938 ChemDiv3_012436 Fc1cccc(F)c1CSc2nc3ccccc3c(=O)n2Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F07 compound treatment 0.27 0.0462 0.66 0.297 0.0758 1.27 1.3665 0.9534 3121838 ChemDiv3_012437 CCOc1ccccc1n2c(N)c(C#N)c(N)c(C#N)c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F08 compound treatment 0.305 0.0812 1.16 0.294 0.0728 1.22 1.6849 0.9997 1429743 ChemDiv3_012438 O=C(CSc1nc2ccccc2c3nc4ccccc4n13)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F09 compound treatment 0.255 0.0312 0.45 0.234 0.0128 0.21 0.4671 0.9437 3121839 ChemDiv3_012439 NS(=O)(=O)c1ccc(CCn2c(=O)c3sc4ccccc4c3[nH]c2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F10 compound treatment 0.303 0.0792 1.13 0.307 0.0858 1.44 1.819 0.993 1534154 ChemDiv3_012440 O=c1n(C2CCCC2)c(=S)[nH]c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F11 compound treatment 0.266 0.0422 0.6 0.3 0.0788 1.32 1.3617 0.9369 3121840 ChemDiv3_012441 CCCCn1c(SCC(=O)NCc2ccccc2)nc3c4ccccc4sc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F12 compound treatment 0.293 0.0692 0.99 0.287 0.0658 1.1 1.4805 0.9985 1166876 ChemDiv3_012442 O=C(CSc1nc2ccccc2c(=O)n1NC(=O)c3ccccc3)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F13 compound treatment 0.279 0.0552 0.79 0.303 0.0818 1.37 1.5288 0.9655 3036601 ChemDiv3_012443 O/C(=C\1/C(=O)Nc2ccccc12)/C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F14 compound treatment 0.299 0.0752 1.08 0.242 0.0208 0.35 1.0071 0.8908 1501852 ChemDiv3_012444 O=C(CCn1c(SCC#N)nc2ccccc2c1=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F15 compound treatment 0.291 0.0672 0.96 0.235 0.0138 0.23 0.8431 0.8529 3036644 ChemDiv3_012445 CCN1C(=S)NC2C(C(=O)Nc3ccc(Cl)cc3)C1(C)Oc4ccc(Br)cc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F16 compound treatment 0.247 0.0232 0.33 0.254 0.0328 0.55 0.6236 0.9706 1342889 ChemDiv3_012446 Fc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2CCCC(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F17 compound treatment 0.3 0.0762 1.09 0.301 0.0798 1.34 1.7174 0.9948 1680152 ChemDiv3_012447 COc1ccc2oc(=O)c(cc2c1)c3nc(cs3)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F18 compound treatment 0.277 0.0532 0.76 0.297 0.0758 1.27 1.4373 0.9698 1164499 ChemDiv3_012448 CCOC(=O)CSc1nc2ccc(Br)cc2c3nc4ccccc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F19 compound treatment 0.292 0.0682 0.98 0.252 0.0308 0.52 1.055 0.9558 3036647 ChemDiv3_012449 CC(C)C1N=C2N(C1=O)C(=Nc3ccccc23)SCC(=O)c4ccc(Br)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F20 compound treatment 0.249 0.0252 0.36 0.235 0.0138 0.23 0.4183 0.9771 3036648 ChemDiv3_012450 Fc1cccc(CSc2nc3ccccc3c(=O)n2C4CC4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F21 compound treatment 0.27 0.0462 0.66 0.267 0.0458 0.77 1.0105 0.9972 3121841 ChemDiv3_012451 O=C(CCC1N=C2N(C1=O)C(=S)Nc3ccccc23)NC4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F22 compound treatment 0.27 0.0462 0.66 0.236 0.0148 0.25 0.6426 0.9106 3121842 ChemDiv3_012452 Fc1ccccc1N2CCN(CC2)C(=O)CCCn3c(=O)c4cc5OCOc5cc4[nH]c3=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F23 mock treatment 0.264 0.0402 0.57 0.243 0.0218 0.37 0.665 0.9761 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 F24 mock treatment 0.212 -0.0118 -0.17 0.231 0.00978 0.16 -0.0034 -0.0144 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G01 compound treatment 0.24 0.0162 0.23 0.227 0.00578 0.1 0.2323 0.9255 3036650 ChemDiv3_012453 CC1Cc2cc(ccc2N1C(=O)C)S(=O)(=O)N(C)CC(=O)N(C)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G02 compound treatment 0.233 0.00919 0.13 0.217 -0.00422 -0.07 0.0429 0.2871 1923050 ChemDiv3_012454 O=C/1OC(=N\C1=C/c2ccccc2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G03 compound treatment 0.286 0.0622 0.89 0.294 0.0728 1.22 1.4928 0.9879 3121843 ChemDiv3_012455 CCN(CC)C(=O)Cn1cc(SCC(=O)N2CCCCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G04 compound treatment 0.288 0.0642 0.92 0.274 0.0528 0.89 1.2756 0.9998 3036653 ChemDiv3_012456 Cc1ccc(cc1C)N2C(SCC2=O)c3ccccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G05 compound treatment 0.294 0.0702 1.0 0.271 0.0498 0.84 1.3007 0.9958 3121844 ChemDiv3_012457 O=C(CSc1cn(CC(=O)N2CCOCC2)c3ccccc13)NCc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G06 compound treatment 0.259 0.0352 0.5 0.242 0.0208 0.35 0.6025 0.984 3121845 ChemDiv3_012458 O=C(NCc1ccccc1)c2ccc3nc(c4cccs4)c(nc3c2)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G07 compound treatment 0.271 0.0472 0.67 0.225 0.00378 0.06 0.5221 0.7702 3036656 ChemDiv3_012459 CCOC(=O)C1=C(CN2CCC(=CC2)c3ccccc3)NC(=O)NC1c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G08 compound treatment 0.268 0.0442 0.63 0.267 0.0458 0.77 0.9903 0.9953 3121846 ChemDiv3_012460 COc1ccc(NC(=O)c/2cc3ccc(O)cc3o\c2=N/c4ccc(cc4)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G09 compound treatment 0.315 0.0912 1.3 0.304 0.0828 1.39 1.9047 0.9995 3036658 ChemDiv3_012461 CN(C)CCN(C(=O)c1ccco1)c2nc3ccc(C)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G10 compound treatment 0.325 0.101 1.45 0.324 0.103 1.73 2.2433 0.9962 3121847 ChemDiv3_012462 CCOc1cc2[nH]c(=O)n(CCC(=O)NC3CCCCC3C)c(=O)c2cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G11 compound treatment 0.275 0.0512 0.73 0.31 0.0888 1.49 1.5714 0.9465 3036660 ChemDiv3_012463 COc1ccc2sc(nc2c1)N(CCN(C)C)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G12 compound treatment 0.283 0.0592 0.85 0.284 0.0628 1.05 1.3437 0.9941 3121848 ChemDiv3_012464 CCc1ccc(/N=c/2\oc3c(C)ncc(CO)c3cc2C(=O)N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G13 compound treatment 0.31 0.0862 1.23 0.223 0.00178 0.03 0.8929 0.724 3121849 ChemDiv3_012465 Cc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G14 compound treatment 0.236 0.0122 0.17 0.215 -0.00622 -0.1 0.0495 0.2434 1158935 ChemDiv3_012466 CCc1ccc(Nc2nc(cs2)c3cc4ccccc4oc3=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G15 compound treatment 0.248 0.0242 0.35 0.254 0.0328 0.55 0.6337 0.975 3121850 ChemDiv3_012467 COc1ccc(Nc2nc(nc3n(C)ncc23)N4CCN(CCO)CC4)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G16 compound treatment 0.307 0.0832 1.19 0.294 0.0728 1.22 1.7052 0.9999 3036662 ChemDiv3_012468 Clc1ccc(cc1)c2nnn3c2[nH]c(=O)c4ccccc43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G17 compound treatment 0.299 0.0752 1.08 0.237 0.0158 0.26 0.9478 0.8557 1396293 ChemDiv3_012469 CC(C)(C)c1ccc(cc1)C(=O)N2CCC(CC2)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G18 compound treatment 0.114 -0.11 -1.57 0.098 -0.123 -2.07 -2.573 -0.9908 3036664 ChemDiv3_012470 Cc1ccc(c(C)c1)n2cc([nH]c2=S)c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G19 compound treatment 0.246 0.0222 0.32 0.262 0.0408 0.68 0.7084 0.9389 3122038 ChemDiv3_012471 CCOC(=O)c1c(C)c(C)sc1NC(=O)Nc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G20 compound treatment 0.249 0.0252 0.36 0.231 0.00978 0.16 0.3708 0.9367 3122039 ChemDiv3_012472 Cc1ccc(NC(=O)CSc2nc(cn2c3cccc(Cl)c3)c4ccc5OCOc5c4)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G21 compound treatment 0.242 0.0182 0.26 0.22 -0.00122 -0.02 0.1695 0.6495 3036666 ChemDiv3_012473 C(=N/n1cnnc1)\c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G22 compound treatment 0.239 0.0152 0.22 0.183 -0.0382 -0.64 -0.3 -0.4429 3035632 ChemDiv3_012474 O=C(CSc1nc2ccccc2c3nc4ccccc4n13)NCc5ccco5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G23 mock treatment 0.216 -0.00781 -0.11 0.22 -0.00122 -0.02 -0.0935 -0.8229 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 G24 mock treatment 0.205 -0.0188 -0.27 0.197 -0.0242 -0.41 -0.4777 -0.9799 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H01 compound treatment 0.264 0.0402 0.57 0.239 0.0178 0.3 0.6175 0.9534 3035560 ChemDiv3_012475 COc1ccc(OCC(=O)Nn2c(=O)c3cccnc3[nH]c2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H02 compound treatment 0.266 0.0422 0.6 0.249 0.0278 0.47 0.7564 0.9919 3035562 ChemDiv3_012476 Cc1cc(C)n(CCc2nc3c4ccccc4nc(SCc5ccc(C)cc5)n3n2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H03 compound treatment 0.315 0.0912 1.3 0.275 0.0538 0.9 1.5606 0.9838 3035563 ChemDiv3_012477 O=C(CCCC1=Nc2ccccc2S(=O)(=O)N1)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H04 compound treatment 0.268 0.0442 0.63 0.31 0.0888 1.49 1.5006 0.9271 1726645 ChemDiv3_012478 COC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(SCC(=O)C(C)(C)C)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H05 compound treatment 0.302 0.0782 1.12 0.283 0.0618 1.04 1.524 0.9993 3035566 ChemDiv3_012479 Clc1ccc(cc1)N2C(=O)N(Cc3cc(=O)n4ccccc4n3)c5ccccc5S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H06 compound treatment 0.327 0.103 1.48 0.272 0.0508 0.85 1.6463 0.9659 1217521 ChemDiv3_012480 Cc1ccc(CSc2nc3ccccc3c(=O)n2CCc4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H07 compound treatment 0.3 0.0762 1.09 0.3 0.0788 1.32 1.7056 0.9954 3035568 ChemDiv3_012481 Nc1c(C#N)c(N)n(CC2CCCO2)c(=S)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H08 compound treatment 0.376 0.152 2.18 0.363 0.142 2.38 3.2219 0.999 1739931 ChemDiv3_012482 COC(=O)c1ccc2c3nc4ccccc4n3c(SCc5ccccc5Cl)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H09 compound treatment 0.315 0.0912 1.3 0.314 0.0928 1.56 2.0234 0.9961 3122040 ChemDiv3_012483 CCCCC(CC)Cn1c(=O)c2sc3ccccc3c2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H10 compound treatment 0.252 0.0282 0.4 0.253 0.0318 0.53 0.6623 0.9905 1290113 ChemDiv3_012484 O=c1n(CC2COc3ccccc3O2)c(=S)[nH]c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H11 compound treatment 0.333 0.109 1.56 0.311 0.0898 1.51 2.1699 0.9998 3122041 ChemDiv3_012485 CCCCn1c(SCC(=O)NC2CCCC2)nc3c4ccccc4sc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H12 compound treatment 0.328 0.104 1.49 0.315 0.0938 1.57 2.1668 0.9996 1516861 ChemDiv3_012486 O=C(Cc1ccccc1)Nn2c(SCC(=O)c3ccccc3)nc4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H13 compound treatment 0.305 0.0812 1.16 0.251 0.0298 0.5 1.1746 0.9291 3122042 ChemDiv3_012487 O/C(=C\1/C(=O)Nc2ccccc12)/C(=O)Nc3ccc4ccccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H14 compound treatment 0.239 0.0152 0.22 0.19 -0.0312 -0.52 -0.2169 -0.3824 1425823 ChemDiv3_012488 COc1cccc(NC(=O)CCn2c(=O)c3ccccc3[nH]c2=S)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H15 compound treatment 0.313 0.0892 1.28 0.327 0.106 1.78 2.1575 0.9869 3035573 ChemDiv3_012489 CC1(CC2NC(=S)N1c3ccccc3)Oc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H16 compound treatment 0.296 0.0722 1.03 0.31 0.0888 1.49 1.7838 0.9839 1579697 ChemDiv3_012490 CCOC(CCn1c(SCc2cc(=O)n3ccccc3n2)nc4ccccc4c1=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H17 compound treatment 0.296 0.0722 1.03 0.313 0.0918 1.54 1.8194 0.9811 1412676 ChemDiv3_012491 CC(=O)Oc1ccc2cc(c3nc(c(C)s3)c4ccccc4)c(=O)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H18 compound treatment 0.306 0.0822 1.18 0.274 0.0528 0.89 1.4577 0.9903 3122043 ChemDiv3_012492 CCC(C)NC(=O)CSc1nc2ccc(Br)cc2c3nc4ccccc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H19 compound treatment 0.18 -0.0438 -0.63 0.206 -0.0152 -0.26 -0.6237 -0.9217 3122044 ChemDiv3_012493 CC(C)C1N=C2N(C1=O)C(=Nc3ccccc23)SCc4ccccc4F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H20 compound treatment 0.267 0.0432 0.62 0.214 -0.00722 -0.12 0.3511 0.5578 3035576 ChemDiv3_012494 CCN(CCCn1c(=O)c2cc3OCOc3cc2[nH]c1=S)c4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H21 compound treatment 0.286 0.0622 0.89 0.281 0.0598 1.0 1.3385 0.9982 3122045 ChemDiv3_012495 O=C(CC1N=C2N(C1=O)C(=S)Nc3ccccc23)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H22 compound treatment 0.232 0.00819 0.12 0.225 0.00378 0.06 0.1277 0.9586 3035579 ChemDiv3_012496 C=CCNC(=O)CCn1c(=O)c2cc3OCOc3cc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H23 mock treatment 0.252 0.0282 0.4 0.231 0.00978 0.16 0.4012 0.9216 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 H24 mock treatment 0.19 -0.0338 -0.48 0.207 -0.0142 -0.24 -0.5107 -0.947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I01 compound treatment 0.229 0.00519 0.07 0.242 0.0208 0.35 0.2991 0.8388 3122046 ChemDiv3_012497 Cc1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2Cc4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I02 compound treatment 0.275 0.0512 0.73 0.24 0.0188 0.32 0.7406 0.9291 3035581 ChemDiv3_012498 COc1ccc(cc1)C2=N/C(=C\c3ccco3)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I03 compound treatment 0.268 0.0442 0.63 0.261 0.0398 0.67 0.919 0.9996 3122047 ChemDiv3_012499 CCN(CC)C(=O)Cn1cc(SCC(=O)N)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I04 compound treatment 0.25 0.0262 0.37 0.289 0.0678 1.14 1.0693 0.8928 1325020 ChemDiv3_012500 COc1ccc(cc1)N2C(SCC2=O)c3cccc(OC)c3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I05 compound treatment 0.268 0.0442 0.63 0.3 0.0788 1.32 1.3819 0.9429 3035634 ChemDiv3_012501 CC1CCN(CC1)C(=O)Cn2cc(SCC(=O)N3CCc4ccccc34)c5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I06 compound treatment 0.268 0.0442 0.63 0.241 0.0198 0.33 0.6817 0.9548 3035635 ChemDiv3_012502 CCC(C)NC(=O)c1ccc2nc(c3cccs3)c(nc2c1)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I07 compound treatment 0.306 0.0822 1.18 0.304 0.0828 1.39 1.8137 0.9965 3035637 ChemDiv3_012503 Cc1cc([nH]n1)C(=O)N2CCN(Cc3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I08 compound treatment 0.315 0.0912 1.3 0.288 0.0668 1.12 1.7149 0.9972 3035638 ChemDiv3_012504 COc1ccc(CNC(=O)CCn2c(=O)[nH]c3ccccc3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I09 compound treatment 0.291 0.0672 0.96 0.328 0.107 1.79 1.9468 0.9573 3122048 ChemDiv3_012505 COc1ccc2nc(sc2c1)N(CCN(C)C)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I10 compound treatment 0.277 0.0532 0.76 0.281 0.0598 1.0 1.2474 0.9907 3122049 ChemDiv3_012506 CC1CCCC(NC(=O)C2CCC(Cn3c(=O)[nH]c4ccccc4c3=O)CC2)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I11 compound treatment 0.295 0.0712 1.02 0.213 -0.00822 -0.14 0.6225 0.6058 3035641 ChemDiv3_012507 COc1ccc2sc(nc2c1)N(CCN(C)C)C(=O)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I12 compound treatment 0.293 0.0692 0.99 0.249 0.0278 0.47 1.0295 0.941 3122050 ChemDiv3_012508 Cc1ncc(CO)c2cc(C(=O)Nc3ccccc3)/c(=N/c4ccccc4)/oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I13 compound treatment 0.262 0.0382 0.55 0.258 0.0368 0.62 0.8228 0.9981 3035643 ChemDiv3_012509 COc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)Nc3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I14 compound treatment 0.276 0.0522 0.75 0.232 0.0108 0.18 0.6558 0.8538 3122051 ChemDiv3_012510 CC(=O)N(c1nc(cs1)c2cc3ccccc3oc2=O)c4cccc(C)c4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I15 compound treatment 0.289 0.0652 0.93 0.289 0.0678 1.14 1.4638 0.9951 3035645 ChemDiv3_012511 COc1ccccc1N2CCN(CC2)c3nc(Nc4ccc(C)cc4)c5cnn(C)c5n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I16 compound treatment 0.239 0.0152 0.22 0.286 0.0648 1.09 0.9224 0.8319 3122052 ChemDiv3_012512 FC(F)(F)c1cccc(c1)c2nnn3c2[nH]c(=O)c4ccccc43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I17 compound treatment 0.042 -0.182 -2.6 0.058 -0.163 -2.74 -3.776 -0.9997 3035648 ChemDiv3_012513 Oc1c(Br)cc(Br)cc1/C=N/N2C(=O)CSC2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I18 compound treatment 0.297 0.0732 1.05 0.274 0.0528 0.89 1.3666 0.9965 3122053 ChemDiv3_012514 Fc1ccc(cc1)n2cc([nH]c2=S)c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I19 compound treatment 0.273 0.0492 0.7 0.27 0.0488 0.82 1.0764 0.9971 3122054 ChemDiv3_012515 C1COCCOc2cc(/N=C\c3c[nH]c4ccccc34)ccc2OCCO1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I20 compound treatment 0.258 0.0342 0.49 0.231 0.00978 0.16 0.4619 0.8954 3035650 ChemDiv3_012516 CC(C)(C)C1=Nn2c(nnc2SC1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I21 compound treatment 0.203 -0.0208 -0.3 0.215 -0.00622 -0.1 -0.2843 -0.9012 3122055 ChemDiv3_012517 CN(/N=C/c1ccc(C)o1)C2=NCCN2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I22 compound treatment 0.226 0.00219 0.03 0.234 0.0128 0.21 0.1738 0.8018 3035652 ChemDiv3_012518 O=C(CSc1nc2ccccc2c3nc4ccccc4n13)NCCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I23 mock treatment 0.187 -0.0368 -0.53 0.212 -0.00922 -0.15 -0.4817 -0.8778 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 I24 mock treatment 0.215 -0.00881 -0.13 0.221 -2.19E-4 0.0 -0.0917 -0.7274 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J01 compound treatment 0.253 0.0292 0.42 0.236 0.0148 0.25 0.4706 0.9691 3122056 ChemDiv3_012519 C=CCNC(=O)Cn1c(=O)c2cccnc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J02 compound treatment 0.244 0.0202 0.29 0.227 0.00578 0.1 0.2728 0.8955 3122057 ChemDiv3_012520 Cc1nc2c3ccccc3nc(SCc4cc(F)cc5COCOc45)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J03 compound treatment 0.302 0.0782 1.12 0.251 0.0298 0.5 1.1443 0.9341 3035654 ChemDiv3_012521 CC(CC(=O)O)CC1=Nc2ccccc2S(=O)(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J04 compound treatment 0.211 -0.0128 -0.18 0.244 0.0228 0.38 0.1408 0.332 1191560 ChemDiv3_012522 CC1CCCC(C1C)n2c(=O)c3ccccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J05 compound treatment 0.282 0.0582 0.83 0.275 0.0538 0.9 1.2268 0.9992 3122058 ChemDiv3_012523 Clc1ccc(cc1)N2C(=O)N(CC(=O)N3CCCc4ccccc34)c5ccccc5S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J06 compound treatment 0.242 0.0182 0.26 0.239 0.0178 0.3 0.395 0.9977 1311026 ChemDiv3_012524 Cc1ccc(CSc2nc3ccccc3c(=O)n2Cc4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J07 compound treatment 0.285 0.0612 0.88 0.324 0.103 1.73 1.8387 0.9505 3035657 ChemDiv3_012525 CSc1nc2c3ccccc3sc2c(=O)n1c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J08 compound treatment 0.31 0.0862 1.23 0.257 0.0358 0.6 1.2964 0.9454 1488534 ChemDiv3_012526 CC1CCCCC1NC(=O)c2ccc3c(=O)n(CCCN4CCCC4=O)c(=S)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J09 compound treatment 0.299 0.0752 1.08 0.295 0.0738 1.24 1.6361 0.9975 3122059 ChemDiv3_012527 Fc1ccccc1N2CCN(CCCn3c(=O)c4sc5ccccc5c4[nH]c3=S)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J10 compound treatment 0.266 0.0422 0.6 0.296 0.0748 1.26 1.3142 0.9437 1733498 ChemDiv3_012528 CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J11 compound treatment 0.288 0.0642 0.92 0.286 0.0648 1.09 1.418 0.9965 3035717 ChemDiv3_012529 O=c1n(C2CCCCC2)c(SCC#N)nc3c4ccccc4sc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J12 compound treatment 0.277 0.0532 0.76 0.302 0.0808 1.36 1.4967 0.9627 3035719 ChemDiv3_012530 O=c1n(CCn2c(SCC#N)nc3ccccc3c2=O)c(SCC#N)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J13 compound treatment 0.234 0.0102 0.15 0.281 0.0598 1.0 0.8125 0.8014 3443559 ChemDiv3_012531 CCOC(=O)C1C2NC(=S)N(c3ccccc3)C1(C)Oc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J14 compound treatment 0.224 1.88E-4 0.0 0.215 -0.00622 -0.1 -0.0719 -0.6887 1675251 ChemDiv3_012532 O=C(NCC1CCCO1)c2ccc(Cn3c(=O)c4ccccc4[nH]c3=S)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J15 compound treatment 0.228 0.00419 0.06 0.244 0.0228 0.38 0.3127 0.808 3035721 ChemDiv3_012533 COc1ccc(CCN2C(=S)NC3CC2(C)Oc4c(OC)cc(Br)cc34)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J16 compound treatment 0.261 0.0372 0.53 0.254 0.0328 0.55 0.7652 0.9999 1729416 ChemDiv3_012534 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)Nc3ccc(C)cc3)nc4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J17 compound treatment 0.259 0.0352 0.5 0.219 -0.00222 -0.04 0.3296 0.653 1733506 ChemDiv3_012535 CC(=O)Oc1ccc2cc(c3nc-4c(CCc5ccccc45)s3)c(=O)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J18 compound treatment 0.264 0.0402 0.57 0.286 0.0648 1.09 1.1753 0.9556 1577061 ChemDiv3_012536 CCC(Sc1nc2ccc(Br)cc2c3nc4ccccc4n13)C(=O)NCC5CCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J19 compound treatment 0.297 0.0732 1.05 0.267 0.0458 0.77 1.2836 0.9884 3122243 ChemDiv3_012537 COc1ccc(CCNC(=O)CSC2=Nc3ccccc3C4=NC(C(C)C)C(=O)N42)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J20 compound treatment 0.235 0.0112 0.16 0.216 -0.00522 -0.09 0.0512 0.2808 3035725 ChemDiv3_012538 Clc1ccccc1CCn2c(=O)c3cc4OCOc4cc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J21 compound treatment 0.265 0.0412 0.59 0.288 0.0668 1.12 1.2091 0.9549 3122244 ChemDiv3_012539 CC(C)NC(=O)CC1N=C2N(C1=O)C(=S)Nc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J22 compound treatment 0.229 0.00519 0.07 0.247 0.0258 0.43 0.3584 0.8164 3122245 ChemDiv3_012540 CCOC(=O)N1CCN(CC1)C(=O)CCn2c(=O)c3cc4OCOc4cc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J23 mock treatment 0.256 0.0322 0.46 0.233 0.0118 0.2 0.4654 0.9288 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 J24 mock treatment 0.182 -0.0418 -0.6 0.217 -0.00422 -0.07 -0.473 -0.7853 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K01 compound treatment 0.248 0.0242 0.35 0.259 0.0378 0.63 0.693 0.9594 3035727 ChemDiv3_012541 O=C(CSc1nc2CCSc2c(=O)n1Cc3ccccc3)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K02 compound treatment 0.282 0.0582 0.83 0.257 0.0358 0.6 1.0132 0.9872 3122246 ChemDiv3_012542 COc1ccc(/C=C/2\N=C(\OC2=O)/C=C/c3ccc(C)cc3)cc1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K03 compound treatment 0.315 0.0912 1.3 0.279 0.0578 0.97 1.608 0.9894 3035729 ChemDiv3_012543 CCN(CC)C(=O)Cn1cc(SCc2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K04 compound treatment 0.304 0.0802 1.15 0.274 0.0528 0.89 1.4374 0.9919 1694239 ChemDiv3_012544 Cc1onc(c1C(=O)NCC2(CC3CC4CC(C3)C2)C4)c5ccccc5Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K05 compound treatment 0.25 0.0262 0.37 0.263 0.0418 0.7 0.7607 0.9569 3122247 ChemDiv3_012545 CNC(=O)CSc1cn(CC(=O)N2CCC(C)CC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K06 compound treatment 0.282 0.0582 0.83 0.284 0.0628 1.05 1.3336 0.9932 3035731 ChemDiv3_012546 CC(C)CCNC(=O)c1ccc2nc(c3cccs3)c(nc2c1)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K07 compound treatment 0.256 0.0322 0.46 0.275 0.0538 0.9 0.9638 0.9512 3122248 ChemDiv3_012547 Fc1ccc(cc1)c2cc([nH]n2)C(=O)N3CCN(CC3)c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K08 compound treatment 0.296 0.0722 1.03 0.29 0.0688 1.15 1.5464 0.9985 3035733 ChemDiv3_012548 O=C(CCn1c(=O)[nH]c2ccccc2c1=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K09 compound treatment 0.237 0.0132 0.19 0.261 0.0398 0.67 0.6055 0.8727 3122249 ChemDiv3_012549 CN(C)CCN(C(=O)c1ccc(Br)cc1)c2nc3ccc(Cl)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K10 compound treatment 0.282 0.0582 0.83 0.26 0.0388 0.65 1.0488 0.9926 3122250 ChemDiv3_012550 CC(C)CCNC(=O)C1CCC(Cn2c(=O)[nH]c3ccccc3c2=O)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K11 compound treatment 0.278 0.0542 0.78 0.261 0.0398 0.67 1.0202 0.9972 3035735 ChemDiv3_012551 CN(C)CCN(C(=O)C)c1nc2cc(C)cc(C)c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K12 compound treatment 0.27 0.0462 0.66 0.258 0.0368 0.62 0.9037 0.9994 3122251 ChemDiv3_012552 Cc1ncc(CO)c2cc(c3nnc(Nc4cc(ccc4Cl)C(F)(F)F)s3)c(=O)oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K13 compound treatment 0.242 0.0182 0.26 0.248 0.0268 0.45 0.5018 0.9662 3035787 ChemDiv3_012553 COc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)NCc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K14 compound treatment 0.254 0.0302 0.43 0.274 0.0528 0.89 0.9317 0.9454 3035789 ChemDiv3_012554 CCOC(=O)c1ccc(cc1)N(C(=O)C)c2nc(cs2)c3cc4cccc(OCC)c4oc3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K15 compound treatment 0.237 0.0132 0.19 0.273 0.0518 0.87 0.7479 0.841 3035791 ChemDiv3_012555 COc1ccc(cc1OC)C(CC(=O)NCc2ccc(C)cc2)N3Cc4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K16 compound treatment 0.246 0.0222 0.32 0.255 0.0338 0.57 0.6253 0.9624 3035793 ChemDiv3_012556 COc1ccc(CCNC(=O)c2nnn(c2N)c3cccc(C)c3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K17 compound treatment 0.226 0.00219 0.03 0.233 0.0118 0.2 0.1619 0.8089 3035794 ChemDiv3_012557 COc1cccc(/C=N/N2C(=O)CSC2=S)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K18 compound treatment 0.229 0.00519 0.07 0.247 0.0258 0.43 0.3584 0.8164 3035796 ChemDiv3_012558 COc1cccc2cc(c3cn(c4ccc(F)c(F)c4)c(=S)[nH]3)c(=O)oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K19 compound treatment 0.251 0.0272 0.39 0.241 0.0198 0.33 0.5097 0.9969 3122252 ChemDiv3_012559 Clc1ccc(/C=N\c2ccc3OCCOCCOCCOc3c2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K20 compound treatment 0.277 0.0532 0.76 0.229 0.00778 0.13 0.6303 0.8165 3035798 ChemDiv3_012560 Brc1ccc(cc1)C2=Nn3c(SC2)nc4ccccc4c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K21 compound treatment 0.256 0.0322 0.46 0.267 0.0458 0.77 0.8689 0.97 3122253 ChemDiv3_012561 Cc1ccc(cc1)C2=N/C(=C\c3ccco3)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K22 compound treatment 0.233 0.00919 0.13 0.185 -0.0362 -0.61 -0.3369 -0.5417 3035800 ChemDiv3_012562 CCN(C(=O)CSc1nc2ccccc2c3nc4ccccc4n13)c5cccc(C)c5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K23 mock treatment 0.197 -0.0268 -0.38 0.2 -0.0212 -0.36 -0.523 -0.9993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 K24 mock treatment 0.188 -0.0358 -0.51 0.199 -0.0222 -0.37 -0.6259 -0.9878 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L01 compound treatment 0.279 0.0552 0.79 0.244 0.0228 0.38 0.8285 0.9446 3122254 ChemDiv3_012563 COC(=O)c1cccnc1NC(=S)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L02 compound treatment 0.295 0.0712 1.02 0.228 0.00678 0.11 0.8005 0.7813 3122255 ChemDiv3_012564 CCC(Sc1nc2ccccc2c3nc(C)nn13)C(=O)Nc4cc(OC)ccc4OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L03 compound treatment 0.276 0.0522 0.75 0.291 0.0698 1.17 1.356 0.9763 3035802 ChemDiv3_012565 OC(=O)CC1(CC2=Nc3ccccc3S(=O)(=O)N2)CCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L04 compound treatment 0.284 0.0602 0.86 0.285 0.0638 1.07 1.3657 0.9942 1540848 ChemDiv3_012566 CSc1nc2ccccc2c(=O)n1C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L05 compound treatment 0.278 0.0542 0.78 0.286 0.0648 1.09 1.3169 0.9862 3122256 ChemDiv3_012567 Cc1ccc(cc1Cl)N2C(=O)N(CC(=O)Nc3ccccc3)c4ccccc4S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L06 compound treatment 0.268 0.0442 0.63 0.224 0.00278 0.05 0.4799 0.7573 1685213 ChemDiv3_012568 Brc1ccccc1OCC(=O)Nn2c(=O)c3ccccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L07 compound treatment 0.32 0.0962 1.38 0.295 0.0738 1.24 1.8485 0.9986 3122257 ChemDiv3_012569 O=C(CSc1nc2c3ccccc3sc2c(=O)n1c4ccccc4)N5CCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L08 compound treatment 0.279 0.0552 0.79 0.296 0.0748 1.26 1.4457 0.975 3035806 ChemDiv3_012570 O=C(NCCCN1CCOCC1)c2ccc3c(=O)n(CCCN4CCCC4=O)c(=S)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L09 compound treatment 0.261 0.0372 0.53 0.242 0.0208 0.35 0.6228 0.9791 3122258 ChemDiv3_012571 CCN(CC)CCn1c(SCC(=O)Nc2cccc(OC)c2)nc3c4ccccc4sc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L10 compound treatment 0.246 0.0222 0.32 0.272 0.0508 0.85 0.8271 0.9094 1627035 ChemDiv3_012572 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CC4COc5ccccc5O4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L11 compound treatment 0.286 0.0622 0.89 0.294 0.0728 1.22 1.4928 0.9879 3035808 ChemDiv3_012573 Cc1ccc(NC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CC5CCCO5)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L12 compound treatment 0.297 0.0732 1.05 0.298 0.0768 1.29 1.6515 0.9947 1362140 ChemDiv3_012574 CCOC(Cn1c(SCC#N)nc2ccccc2c1=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L13 compound treatment 0.291 0.0672 0.96 0.276 0.0548 0.92 1.3297 0.9998 3122259 ChemDiv3_012575 CCOc1cccc2C3NC(=S)N(CCOC)C(C)(Oc12)C3C(=O)Nc4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L14 compound treatment 0.256 0.0322 0.46 0.282 0.0608 1.02 1.0469 0.9354 1500074 ChemDiv3_012576 O=C(NC1CCCCC1)c2ccc(Cn3c(=O)c4ccccc4[nH]c3=S)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L15 compound treatment 0.25 0.0262 0.37 0.321 0.0998 1.67 1.4491 0.8444 3122260 ChemDiv3_012577 CC1(CC2C(C(=O)c3ccccc3)C(=O)N1)Oc4c(Br)cc(Br)cc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L16 compound treatment 0.305 0.0812 1.16 0.274 0.0528 0.89 1.4476 0.9911 1425362 ChemDiv3_012578 COc1ccc(CCNC(=O)CCn2c(SCC#N)nc3ccccc3c2=O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L17 compound treatment 0.24 0.0162 0.23 0.274 0.0528 0.89 0.7901 0.8629 3036527 ChemDiv3_012579 CCN(CC)C(=O)CSC1=Nc2ccccc2C3=NC(Cc4c[nH]c5ccccc45)C(=O)N31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L18 compound treatment 0.288 0.0642 0.92 0.249 0.0278 0.47 0.9789 0.9506 1179823 ChemDiv3_012580 CN(Cc1ccccc1)C(=O)CSc2nc3ccc(Br)cc3c4nc5ccccc5n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L19 compound treatment 0.288 0.0642 0.92 0.288 0.0668 1.12 1.4418 0.9951 3036529 ChemDiv3_012581 CCc1ccc(NC(=O)CSC2=Nc3ccccc3C4=NC(C(C)C)C(=O)N42)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L20 compound treatment 0.277 0.0532 0.76 0.232 0.0108 0.18 0.6659 0.8515 3036532 ChemDiv3_012582 OC(=O)CCCn1c(=O)c2cc3OCOc3cc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L21 compound treatment 0.264 0.0402 0.57 0.239 0.0178 0.3 0.6175 0.9534 3036534 ChemDiv3_012583 O=C(CCC1N=C2N(C1=O)C(=Nc3ccccc23)SCC#N)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L22 compound treatment 0.244 0.0202 0.29 0.242 0.0208 0.35 0.4508 0.9956 3036535 ChemDiv3_012584 O=C(CCn1c(=O)c2cc3OCOc3cc2[nH]c1=S)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L23 mock treatment 0.205 -0.0188 -0.27 0.26 0.0388 0.65 0.27 0.3833 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 L24 mock treatment 0.227 0.00319 0.05 0.194 -0.0272 -0.46 -0.2908 -0.6334 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M01 compound treatment 0.28 0.0562 0.8 0.289 0.0678 1.14 1.3727 0.9855 3122261 ChemDiv3_012585 Cc1ccc(NC(=O)CSc2nc3CCSc3c(=O)n2CCc4ccccc4)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M02 compound treatment 0.248 0.0242 0.35 0.311 0.0898 1.51 1.3102 0.8474 3036538 ChemDiv3_012586 Clc1ccc(cc1)C2=N/C(=C\c3ccccc3)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M03 compound treatment 0.304 0.0802 1.15 0.275 0.0538 0.9 1.4493 0.993 3122262 ChemDiv3_012587 CCN(CC)C(=O)Cn1cc(SCC(=O)N(C(C)C)C(C)C)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M04 compound treatment 0.306 0.0822 1.18 0.25 0.0288 0.48 1.1728 0.9228 3036541 ChemDiv3_012588 Nc1ccc(Br)cc1c2nc3ccccc3[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M05 compound treatment 0.314 0.0902 1.29 0.252 0.0308 0.52 1.2775 0.9193 3122263 ChemDiv3_012589 CCN(CC)C(=O)Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M06 compound treatment 0.24 0.0162 0.23 0.217 -0.00422 -0.07 0.1137 0.4694 3036544 ChemDiv3_012590 O=C(NCc1cccnc1)c2ccc3nc(c4ccco4)c(nc3c2)c5ccco5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M07 compound treatment 0.281 0.0572 0.82 0.29 0.0688 1.15 1.3947 0.9858 3122457 ChemDiv3_012591 Clc1ccc(cc1)c2cc([nH]n2)C(=O)N3CCN(CC3)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M08 compound treatment 0.288 0.0642 0.92 0.299 0.0778 1.31 1.5723 0.9852 3036547 ChemDiv3_012592 O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M09 compound treatment 0.219 -0.00481 -0.07 0.309 0.0878 1.47 0.9931 0.6733 3036603 ChemDiv3_012593 CN(C)CCN(C(=O)C1CCCCC1)c2nc3ccc(Br)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M10 compound treatment 0.258 0.0342 0.49 0.288 0.0668 1.12 1.1383 0.9309 3036605 ChemDiv3_012594 CC1CCCCC1NC(=O)c2ccc3c(=O)n(Cc4ccc5OCOc5c4)c(=O)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M11 compound treatment 0.231 0.00719 0.1 0.277 0.0558 0.94 0.7347 0.7801 3036607 ChemDiv3_012595 CN(C)CCN(C(=O)CN1C(=O)c2ccccc2C1=O)c3nc4c(F)cc(F)cc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M12 compound treatment 0.287 0.0632 0.9 0.268 0.0468 0.79 1.1943 0.9975 3036609 ChemDiv3_012596 Cc1ncc(CO)c2cc(C(=O)Nc3ccc(I)cc3)c(=O)oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M13 compound treatment 0.313 0.0892 1.28 0.255 0.0338 0.57 1.303 0.9333 3036611 ChemDiv3_012597 COc1ccc(cc1)S(=O)(=O)Nc2cncc(c2)C(=O)N3CCN(CC3)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M14 compound treatment 0.295 0.0712 1.02 0.292 0.0708 1.19 1.56 0.9971 3036613 ChemDiv3_012598 CC(=O)N(c1nc(cs1)c2cc3ccccc3oc2=O)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M15 compound treatment 0.248 0.0242 0.35 0.267 0.0458 0.77 0.788 0.9351 3122458 ChemDiv3_012599 CCOC(=O)c1sc2ncn(/N=C/c3ccc4OCCOc4c3)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M16 compound treatment 0.276 0.0522 0.75 0.255 0.0338 0.57 0.9288 0.9908 3036615 ChemDiv3_012600 Cc1cccc(NC(=O)c2nnn(c2N)c3cccc(c3)C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M17 compound treatment 0.066 -0.158 -2.26 0.074 -0.147 -2.47 -3.3434 -0.999 3122459 ChemDiv3_012601 Cc1c(/N=C/c2cc(Br)cc(Br)c2O)cccc1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M18 compound treatment 0.21 -0.0138 -0.2 0.247 0.0258 0.43 0.1663 0.3495 3036617 ChemDiv3_012602 Cc1cccc(c1)n2cc([nH]c2=S)c3cc4cc(Cl)ccc4oc3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M19 compound treatment 0.203 -0.0208 -0.3 0.27 0.0488 0.82 0.3684 0.4229 3122460 ChemDiv3_012603 OC(=O)c1cc(/C=N\c2ccc3OCCOCCOCCOc3c2)ccc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M20 compound treatment 0.239 0.0152 0.22 0.211 -0.0102 -0.17 0.0323 0.1168 3122461 ChemDiv3_012604 O=C(NCCc1ccccc1)c2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M21 compound treatment 0.277 0.0532 0.76 0.241 0.0198 0.33 0.7727 0.9309 3036619 ChemDiv3_012605 Fc1ccccc1C2=N/C(=C\c3cccc(c3)C(F)(F)F)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M22 compound treatment 0.226 0.00219 0.03 0.26 0.0388 0.65 0.4824 0.7402 3122462 ChemDiv3_012606 CC1CC(C)CN(C1)C(=O)CSc2nc3ccccc3c4nc5ccccc5n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M23 mock treatment 0.236 0.0122 0.17 0.207 -0.0142 -0.24 -0.0455 -0.1539 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 M24 mock treatment 0.195 -0.0288 -0.41 0.22 -0.00122 -0.02 -0.3059 -0.7413 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N01 compound treatment 0.258 0.0342 0.49 0.26 0.0388 0.65 0.806 0.9901 3036622 ChemDiv3_012607 Cc1ccc(C)c(Cn2c(C)nc3n(c4ccccc4)c(=S)sc3c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N02 compound treatment 0.247 0.0232 0.33 0.267 0.0458 0.77 0.7779 0.9294 3122463 ChemDiv3_012608 Cc1nc2c3ccccc3nc(SCc4cccc(c4)C(F)(F)F)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N03 compound treatment 0.254 0.0302 0.43 0.297 0.0758 1.27 1.2047 0.8969 3122464 ChemDiv3_012609 CC(CC(=O)N1CCc2ccccc2C1)CC3=Nc4ccccc4S(=O)(=O)N3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N04 compound treatment 0.332 0.108 1.55 0.273 0.0518 0.87 1.7088 0.9628 1247070 ChemDiv3_012610 Fc1ccccc1CSc2nc3ccccc3c(=O)n2CCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N05 compound treatment 0.336 0.112 1.6 0.256 0.0348 0.58 1.5475 0.9062 3122465 ChemDiv3_012611 CCN(C(=O)CN1C(=O)N(c2ccc(C)c(Cl)c2)S(=O)(=O)c3ccccc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N06 compound treatment 0.06 -0.164 -2.34 0.058 -0.163 -2.74 -3.5939 -0.997 3036627 ChemDiv3_012612 Clc1ccc(CNC(=O)c2ccc3c4nc5ccccc5n4c(=S)[nH]c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N07 compound treatment 0.243 0.0192 0.27 0.295 0.0738 1.24 1.0697 0.8434 3035583 ChemDiv3_012613 NC(=O)CSc1nc2c3ccccc3sc2c(=O)n1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N08 compound treatment 0.288 0.0642 0.92 0.251 0.0298 0.5 1.0027 0.9591 1730072 ChemDiv3_012614 CC(C)NC(=O)c1ccc2c(=O)n(Cc3ccco3)c(=S)[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N09 compound treatment 0.176 -0.0478 -0.68 0.187 -0.0342 -0.57 -0.8897 -0.9962 3035585 ChemDiv3_012615 Cc1cc(NC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CCc5ccccc5)n[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N10 compound treatment 0.294 0.0702 1.0 0.31 0.0888 1.49 1.7636 0.9815 1416226 ChemDiv3_012616 Clc1ccc(CSc2nc3ccccc3c(=O)n2CC4COc5ccccc5O4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N11 compound treatment 0.297 0.0732 1.05 0.252 0.0308 0.52 1.1055 0.947 3035588 ChemDiv3_012617 O=C(CSc1nc2c3ccccc3sc2c(=O)n1CC4CCCO4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N12 compound treatment 0.295 0.0712 1.02 0.276 0.0548 0.92 1.3702 0.9987 1410674 ChemDiv3_012618 CCOC(Cn1c(SCc2c(F)cccc2Cl)nc3ccccc3c1=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N13 compound treatment 0.255 0.0312 0.45 0.261 0.0398 0.67 0.7876 0.9808 3122466 ChemDiv3_012619 COc1cccc2C3NC(=S)N(c4ccc(F)cc4)C(C)(Oc12)C3C(=O)Nc5ccc(C)cc5C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N14 compound treatment 0.271 0.0472 0.67 0.285 0.0638 1.07 1.2342 0.9753 1265476 ChemDiv3_012620 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)NC(C)CC)nc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N15 compound treatment 0.265 0.0412 0.59 0.248 0.0268 0.45 0.7344 0.9911 3035592 ChemDiv3_012621 COc1ccc(/C=C/C(=C/2\C3C4CCCC4(Oc5ccccc35)N(C)C2=O)/O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N16 compound treatment 0.233 0.00919 0.13 0.231 0.00978 0.16 0.209 0.9939 1632146 ChemDiv3_012622 Brc1ccc2[nH]c(=S)n(Cc3ccc(cc3)C(=O)NCc4ccco4)c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N17 compound treatment 0.219 -0.00481 -0.07 0.273 0.0518 0.87 0.5659 0.6491 3122467 ChemDiv3_012623 Fc1ccc(cc1)C(=O)CSC2=Nc3ccccc3C4=NC(Cc5ccccc5)C(=O)N42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N18 compound treatment 0.294 0.0702 1.0 0.22 -0.00122 -0.02 0.6954 0.6926 1249888 ChemDiv3_012624 CCOC(CCn1c(=O)c2ccc(cc2[nH]c1=S)C(=O)OC)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N19 compound treatment 0.269 0.0452 0.65 0.3 0.0788 1.32 1.392 0.9458 3122468 ChemDiv3_012625 COc1cccc(NC(=O)CSC2=Nc3ccccc3C4=NC(C(C)C)C(=O)N42)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N20 compound treatment 0.262 0.0382 0.55 0.275 0.0538 0.9 1.0245 0.971 3035596 ChemDiv3_012626 CCC(Sc1nc2cc3OCOc3cc2c(=O)n1Cc4ccco4)C(=O)Nc5ccccc5OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N21 compound treatment 0.303 0.0792 1.13 0.241 0.0198 0.33 1.0357 0.8775 3122469 ChemDiv3_012627 O=C(CCC1N=C2N(C1=O)C(=Nc3ccccc23)SCC#N)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N22 compound treatment 0.262 0.0382 0.55 0.26 0.0388 0.65 0.8465 0.9962 3122470 ChemDiv3_012628 Cc1cccc(N2CCN(CC2)C(=O)CCn3c(=O)c4cc5OCOc5cc4[nH]c3=S)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N23 mock treatment 0.251 0.0272 0.39 0.23 0.00878 0.15 0.3792 0.9118 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 N24 mock treatment 0.22 -0.00381 -0.05 0.212 -0.00922 -0.15 -0.148 -0.9019 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O01 compound treatment 0.241 0.0172 0.25 0.238 0.0168 0.28 0.373 0.9977 3035598 ChemDiv3_012629 O=C(CSc1nc2CCSc2c(=O)n1CCc3ccccc3)Nc4nccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O02 compound treatment 0.254 0.0302 0.43 0.228 0.00678 0.11 0.3858 0.864 3122471 ChemDiv3_012630 O=C/1O/C(=N\C1=C\c2ccco2)/C=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O03 compound treatment 0.272 0.0482 0.69 0.263 0.0418 0.7 0.9832 1.0 3122472 ChemDiv3_012631 O=C(CSc1cn(CC(=O)N2CCCC2)c3ccccc13)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O04 compound treatment 0.233 0.00919 0.13 0.263 0.0418 0.7 0.5888 0.8253 1274089 ChemDiv3_012632 Oc1ncnc2nc(c3ccccc3)c(nc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O05 compound treatment 0.276 0.0522 0.75 0.231 0.00978 0.16 0.6439 0.8425 3122473 ChemDiv3_012633 CCN(CC)C(=O)Cn1cc(c2ccccc12)S(=O)(=O)CC(=O)Nc3ccccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O06 compound treatment 0.265 0.0412 0.59 0.219 -0.00222 -0.04 0.3902 0.6611 3035659 ChemDiv3_012634 Clc1ccc(/N=c/2\oc3ccccc3cc2C(=O)Nc4nccs4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O07 compound treatment 0.251 0.0272 0.39 0.273 0.0518 0.87 0.8895 0.9342 3035660 ChemDiv3_012635 O=C(NCc1ccccc1)N2CCSc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O08 compound treatment 0.232 0.00819 0.12 0.264 0.0428 0.72 0.5905 0.8117 3035662 ChemDiv3_012636 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(Cn3c(=O)[nH]c4ccccc4c3=O)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O09 compound treatment 0.233 0.00919 0.13 0.223 0.00178 0.03 0.1141 0.8463 3035664 ChemDiv3_012637 CCc1ccc2nc(sc2c1)N(CCN(C)C)C(=O)c3ccc(cc3)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O10 compound treatment 0.243 0.0192 0.27 0.231 0.00978 0.16 0.3102 0.9698 3035665 ChemDiv3_012638 O=C(NCc1ccccc1)c2ccc3c(=O)n(CCC4=CCCCC4)c(=O)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O11 compound treatment 0.246 0.0222 0.32 0.23 0.00878 0.15 0.3286 0.9392 3035668 ChemDiv3_012639 O=C(Nc1ccc2OCOc2c1)c3cncc(NS(=O)(=O)c4ccccc4)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O12 compound treatment 0.254 0.0302 0.43 0.249 0.0278 0.47 0.635 0.9993 3122474 ChemDiv3_012640 Cc1ncc(CO)c2cc(C(=O)NC3=CC4OCOC4C=C3)/c(=N/c5ccccc5)/oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O13 compound treatment 0.247 0.0232 0.33 0.248 0.0268 0.45 0.5524 0.9888 3035669 ChemDiv3_012641 COc1cccc(C(=O)NCCc2csc3nc(nn23)c4ccc(C)cc4)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O14 compound treatment 0.256 0.0322 0.46 0.287 0.0658 1.1 1.1062 0.9248 3122475 ChemDiv3_012642 Brc1ccc2oc(=O)c(cc2c1)c3csc(NC(=O)CCC(=O)N4CCCC4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O15 compound treatment 0.23 0.00619 0.09 0.241 0.0198 0.33 0.2973 0.8654 3035672 ChemDiv3_012643 Cc1cc(c(C)s1)c2cn(/N=C/c3ccc(Cl)cc3Cl)c(N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O16 compound treatment 0.265 0.0412 0.59 0.203 -0.0182 -0.31 0.2004 0.3019 3122476 ChemDiv3_012644 Nc1c(nnn1c2cccc(c2)C(F)(F)F)C(=O)NCCC3=CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O17 compound treatment 0.215 -0.00881 -0.13 0.236 0.0148 0.25 0.0863 0.3101 3035674 ChemDiv3_012645 COc1cccc(/C=N/c2cccc(C(=O)O)c2C)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O18 compound treatment 0.241 0.0172 0.25 0.254 0.0328 0.55 0.5629 0.9341 1347140 ChemDiv3_012646 COc1ccc(cc1)n2cc(nc2SCC(=O)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O19 compound treatment 0.21 -0.0138 -0.2 0.222 7.81E-4 0.01 -0.1304 -0.6587 3035676 ChemDiv3_012647 CN(/N=C/c1ccc(cc1)C(C)(C)C)C2=NCCN2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O20 compound treatment 0.213 -0.0108 -0.15 0.256 0.0348 0.58 0.3034 0.5024 3122477 ChemDiv3_012648 O=C(N1CCCCC1)c2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O21 compound treatment 0.226 0.00219 0.03 0.212 -0.00922 -0.15 -0.0873 -0.5529 3035679 ChemDiv3_012649 CC(=O)Oc1cccc(/C=C/2\N=C(OC2=O)c3ccco3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O22 compound treatment 0.22 -0.00381 -0.05 0.238 0.0168 0.28 0.1606 0.5598 3122478 ChemDiv3_012650 CCN(Cc1ccccc1)C(=O)CSc2nc3ccccc3c4nc5ccccc5n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O23 mock treatment 0.209 -0.0148 -0.21 0.229 0.00778 0.13 -0.0575 -0.2309 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 O24 mock treatment 0.216 -0.00781 -0.11 0.23 0.00878 0.15 0.0252 0.1362 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P01 compound treatment 0.247 0.0232 0.33 0.221 -2.19E-4 0.0 0.2319 0.6992 3035682 ChemDiv3_012651 Cc1ccc2oc(=O)c(cc2c1)c3nc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P02 compound treatment 0.304 0.0802 1.15 0.272 0.0508 0.85 1.4137 0.9893 3122479 ChemDiv3_012652 Cc1n[nH]c(C)c1CCc2nc3c4ccccc4nc(SCc5ccc(C)cc5)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P03 compound treatment 0.266 0.0422 0.6 0.249 0.0278 0.47 0.7564 0.9919 3122670 ChemDiv3_012653 CC(CC(=O)NCc1ccccc1)CC2=Nc3ccccc3S(=O)(=O)N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P04 compound treatment 0.322 0.0982 1.4 0.301 0.0798 1.34 1.9399 0.9997 1381410 ChemDiv3_012654 O=C(CSc1nc2ccccc2c(=O)n1CCc3ccccc3)NCc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P05 compound treatment 0.283 0.0592 0.85 0.25 0.0288 0.48 0.9402 0.9646 3035739 ChemDiv3_012655 O=S1(=O)NC(CC#N)Nc2ccccc21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P06 compound treatment 0.261 0.0372 0.53 0.263 0.0418 0.7 0.872 0.9907 1142918 ChemDiv3_012656 CCOC(=O)CSc1nc2ccccc2c(=O)n1CCN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P07 compound treatment 0.273 0.0492 0.7 0.258 0.0368 0.62 0.934 0.9979 3035742 ChemDiv3_012657 CCOC(=O)CSc1nc2c3ccccc3sc2c(=O)n1Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P08 compound treatment 0.278 0.0542 0.78 0.244 0.0228 0.38 0.8184 0.947 1618070 ChemDiv3_012658 O=C(NCc1ccccc1)C2CCC(Cn3c(=O)c4ccccc4[nH]c3=S)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P09 compound treatment 0.259 0.0352 0.5 0.252 0.0308 0.52 0.7212 0.9999 3035744 ChemDiv3_012659 CCC(Sc1nc2c3ccccc3sc2c(=O)n1CCc4ccccc4)C(=O)N5CCOCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P10 compound treatment 0.276 0.0522 0.75 0.274 0.0528 0.89 1.1542 0.9964 1164910 ChemDiv3_012660 CC(=O)NCCn1c(SCc2ccccc2C)nc3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P11 compound treatment 0.294 0.0702 1.0 0.234 0.0128 0.21 0.8616 0.8393 3035746 ChemDiv3_012661 CCOC(CCn1c(SC)nc2c3ccccc3sc2c1=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P12 compound treatment 0.24 0.0162 0.23 0.233 0.0118 0.2 0.3035 0.9969 1398709 ChemDiv3_012662 CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCCN4CCC(C)CC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P13 compound treatment 0.246 0.0222 0.32 0.239 0.0178 0.3 0.4354 0.9995 3122671 ChemDiv3_012663 Cc1ccc(cc1)N2C(=S)NC3C(C(=O)Nc4ccc(C)cc4C)C2(C)Oc5ccc(Cl)cc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P14 compound treatment 0.255 0.0312 0.45 0.261 0.0398 0.67 0.7876 0.9808 3035748 ChemDiv3_012664 FC(F)(F)c1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2CC4CCCO4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P15 compound treatment 0.244 0.0202 0.29 0.275 0.0538 0.9 0.8425 0.8889 3122672 ChemDiv3_012665 CN1C(=O)C(C2CC1(C)Oc3ccc(Br)cc23)c4nnc(Nc5ccc(C)cc5)s4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P16 compound treatment 0.227 0.00319 0.05 0.229 0.00778 0.13 0.1246 0.9007 1567339 ChemDiv3_012666 CC(C)NC(=O)CCCn1c(=O)c2cc(Br)ccc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P17 compound treatment 0.283 0.0592 0.85 0.285 0.0638 1.07 1.3556 0.9932 3122673 ChemDiv3_012667 Cc1ccc(CNC(=O)CSC2=Nc3ccccc3C4=NC(Cc5ccccc5)C(=O)N42)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P18 compound treatment 0.252 0.0282 0.4 0.232 0.0108 0.18 0.413 0.9346 1672792 ChemDiv3_012668 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)c3ccccc3)nc4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P19 compound treatment 0.262 0.0382 0.55 0.255 0.0338 0.57 0.7872 0.9998 3122674 ChemDiv3_012669 CC1N=C2N(C1=O)C(=Nc3ccccc23)SCC(=O)c4ccc(O)c(O)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P20 compound treatment 0.235 0.0112 0.16 0.295 0.0738 1.24 0.9888 0.7919 3122675 ChemDiv3_012670 CCC(Sc1nc2cc3OCOc3cc2c(=O)n1Cc4ccco4)C(=O)NCc5ccc(C)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P21 compound treatment 0.234 0.0102 0.15 0.268 0.0468 0.79 0.6582 0.8243 3035754 ChemDiv3_012671 O=C(CSC1=Nc2ccccc2C3=NC(CC(=O)NCc4ccco4)C(=O)N31)NCc5ccco5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P22 compound treatment 0.282 0.0582 0.83 0.245 0.0238 0.4 0.8708 0.9433 3122676 ChemDiv3_012672 O=C(NCCC1=CCCCC1)c2ccc(Cn3c(=O)c4cc5OCOc5cc4[nH]c3=S)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P23 mock treatment 0.247 0.0232 0.33 0.237 0.0158 0.26 0.4218 0.9938 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2036 P24 mock treatment 0.216 -0.00781 -0.11 0.226 0.00478 0.08 -0.0223 -0.1619 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A01 compound treatment 0.236 0.0118 0.17 0.202 -0.0173 -0.29 -0.086 -0.2567 3122677 ChemDiv3_012673 CCC(Sc1nc2cc(OC)c(OC)cc2c(=O)n1Cc3ccco3)C(=O)Nc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A02 compound treatment 0.217 -0.00725 -0.1 0.247 0.0277 0.47 0.2559 0.5365 3035757 ChemDiv3_012674 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2C4CC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A03 compound treatment 0.242 0.0177 0.25 0.264 0.0447 0.75 0.7105 0.8963 3122678 ChemDiv3_012675 CCCCn1c(SCC(=O)NCc2ccc(C)cc2)nc3ccc(cc3c1=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A04 compound treatment 0.223 -0.00125 -0.02 0.241 0.0217 0.36 0.2454 0.6717 3035813 ChemDiv3_012676 CCC(Sc1nc2ccsc2c(=O)n1Cc3ccccn3)C(=O)Nc4cccc(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A05 compound treatment 0.251 0.0267 0.38 0.237 0.0177 0.3 0.4811 0.9923 3035815 ChemDiv3_012677 CC(C)CCNC(=O)Cc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A06 compound treatment 0.25 0.0257 0.37 0.234 0.0147 0.25 0.4354 0.9813 3035817 ChemDiv3_012678 Fc1ccc(cc1)C(=O)CSc2nc(NCc3ccccc3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A07 compound treatment 0.216 -0.00825 -0.12 0.204 -0.0153 -0.26 -0.2645 -0.9381 3035819 ChemDiv3_012679 CCOC(=O)c1sc2nc(SCC(=O)C(C)(C)C)n(N)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A08 compound treatment 0.258 0.0338 0.48 0.238 0.0187 0.31 0.5638 0.9785 1269831 ChemDiv3_012680 CCC(Sc1nc(Nc2ccc(F)cc2)c3ccccc3n1)C(=O)Nc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A09 compound treatment 0.218 -0.00625 -0.09 0.26 0.0407 0.68 0.4203 0.6095 3035821 ChemDiv3_012681 CSc1nc2n(c3ccccc3C)c(=S)sc2c(=O)n1c4ccccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A10 compound treatment 0.204 -0.0203 -0.29 0.207 -0.0123 -0.21 -0.3503 -0.986 3122679 ChemDiv3_012682 CN(C)C(=O)c1sc2n(Cc3ccc(F)cc3Cl)c(=O)n(c4ccc(C)c(C)c4)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A11 compound treatment 0.214 -0.0103 -0.15 0.223 0.00374 0.06 -0.0593 -0.3715 1167350 ChemDiv3_012683 COC(Cn1c(=O)c2ccccc2[nH]c1=S)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A12 compound treatment 0.221 -0.00325 -0.05 0.246 0.0267 0.45 0.2845 0.6305 3122680 ChemDiv3_012684 NS(=O)(=O)c1ccc(CCNC(=O)c2cccn3c(=O)c4cc5ccccc5cc4nc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A13 compound treatment 0.211 -0.0133 -0.19 0.241 0.0217 0.36 0.124 0.3016 1294652 ChemDiv3_012685 O=C(N1CCCC1)c2ccc3c(=O)n(CCC4=CCCCC4)c(=S)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A14 compound treatment 0.218 -0.00625 -0.09 0.229 0.00974 0.16 0.0524 0.2812 1234241 ChemDiv3_012686 Cc1cccc(c1)n2ncc3c(NCCc4ccccc4)ncnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A15 compound treatment 0.222 -0.00225 -0.03 0.2 -0.0193 -0.32 -0.2513 -0.7737 1495011 ChemDiv3_012687 CCOC(=O)N1CCN(CC1)C(=O)c2ccc(cc2)n3c(=O)c4ccccc4[nH]c3=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A16 compound treatment 0.244 0.0198 0.28 0.229 0.00974 0.16 0.3154 0.9662 1651200 ChemDiv3_012688 CN(C1CCCCC1)c2ncnc3n(ncc23)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A17 compound treatment 0.242 0.0177 0.25 0.207 -0.0123 -0.21 0.034 0.1042 1429389 ChemDiv3_012689 Cc1ccc(CSc2nc3ccccc3c(=O)n2c4ccc(cc4)C(=O)N5CCOCC5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A18 compound treatment 0.237 0.0127 0.18 0.219 -2.58E-4 0.0 0.1259 0.6901 1418179 ChemDiv3_012690 COc1ccc(cc1)n2cc(c3ccccc3)c4c(NCc5ccccc5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A19 compound treatment 0.219 -0.00525 -0.08 0.196 -0.0233 -0.39 -0.3291 -0.828 1360971 ChemDiv3_012691 CCCN(CCC)C(=O)CSc1nc2ccsc2c(=O)n1Cc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A20 compound treatment 0.226 0.00175 0.03 0.214 -0.00526 -0.09 -0.0447 -0.4873 1414522 ChemDiv3_012692 Fc1ccc(cc1)n2cc(c3ccccc3)c4c(NCc5ccccc5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A21 compound treatment 0.203 -0.0213 -0.3 0.194 -0.0253 -0.42 -0.5147 -0.9867 3035828 ChemDiv3_012693 CCC(C)n1c(SCc2ccccc2Cl)nc3ccsc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A22 compound treatment 0.235 0.0107 0.15 0.237 0.0177 0.3 0.3193 0.9527 1176036 ChemDiv3_012694 Cc1ccc(cc1)n2cc(c3ccccc3)c4c(ncnc24)N5CCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A23 mock treatment 0.216 -0.00825 -0.12 0.214 -0.00526 -0.09 -0.1458 -0.9898 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 A24 mock treatment 0.218 -0.00625 -0.09 0.219 -2.58E-4 0.0 -0.0663 -0.7405 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B01 compound treatment 0.213 -0.0113 -0.16 0.242 0.0227 0.38 0.1561 0.3769 1651169 ChemDiv3_012695 COc1cc2CCN(C(COc3ccc(F)cc3)c2cc1OC)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B02 compound treatment 0.258 0.0338 0.48 0.218 -0.00126 -0.02 0.3264 0.6755 1020986 ChemDiv3_012696 O=C1NCCN1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B03 compound treatment 0.273 0.0488 0.7 0.245 0.0257 0.43 0.7986 0.9735 3035999 ChemDiv3_012697 FC(F)(F)c1ccc(CSC2=NN3CCCC(=O)N=C3S2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B04 compound treatment 0.231 0.00675 0.1 0.263 0.0437 0.73 0.5874 0.7933 3036001 ChemDiv3_012698 Fc1ccc(CN2CCCNC2=O)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B05 compound treatment 0.291 0.0668 0.95 0.254 0.0347 0.58 1.0874 0.972 1222985 ChemDiv3_012699 Cc1cccc(NC(=O)CSc2cn(Cc3cccc(F)c3)c4ccccc24)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B06 compound treatment 0.246 0.0217 0.31 0.282 0.0627 1.05 0.9646 0.8785 3036003 ChemDiv3_012700 COC(=O)c1cn(C)c2ccc(cc2c1=O)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B07 compound treatment 0.219 -0.00525 -0.08 0.241 0.0217 0.36 0.2049 0.5501 1413005 ChemDiv3_012701 Clc1ccccc1Cn2cc(SCC(=O)N3CCCC3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B08 compound treatment 0.228 0.00375 0.05 0.242 0.0227 0.38 0.3078 0.7986 3122681 ChemDiv3_012702 COC(=O)c1cn(C)c2ccc(cc2c1=O)S(=O)(=O)N(C)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B09 compound treatment 0.232 0.00775 0.11 0.237 0.0177 0.3 0.2889 0.9094 3036006 ChemDiv3_012703 COc1ccc(/C=C/C(=O)Nc2ccc(cc2)n3nncc3c4ccc(OC)c(OC)c4)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B10 compound treatment 0.235 0.0107 0.15 0.242 0.0227 0.38 0.3786 0.9201 3122682 ChemDiv3_012704 COC(=O)c1ccc2Sc3ccccc3C(=O)N(Cc4ccccc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B11 compound treatment 0.053 -0.171 -2.45 0.055 -0.164 -2.76 -3.6815 -0.9983 3122683 ChemDiv3_012705 FC(F)(F)c1ccc(NC(=S)N2CCn3cccc3C2c4cccs4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B12 compound treatment 0.237 0.0127 0.18 0.244 0.0247 0.42 0.4226 0.9318 3036008 ChemDiv3_012706 COC(=O)c1onc(C(=O)c2ccccc2)c1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B13 compound treatment 0.235 0.0107 0.15 0.274 0.0547 0.92 0.7584 0.8141 1253507 ChemDiv3_012707 Fc1ccc(cc1)c2cc(C(=O)Nc3cc(F)ccc3F)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B14 compound treatment 0.232 0.00775 0.11 0.263 0.0437 0.73 0.5975 0.8048 3036010 ChemDiv3_012708 CCOC(=O)c1n[nH]c2CCCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B15 compound treatment 0.255 0.0308 0.44 0.25 0.0307 0.52 0.6759 0.9968 1451277 ChemDiv3_012709 COc1ccc(CN2C(=O)C3C4CC(C=C4)C3C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B16 compound treatment 0.249 0.0248 0.35 0.246 0.0267 0.45 0.5677 0.9931 3122684 ChemDiv3_012710 CCN1CCN(CC1)C(=O)/C=C\C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B17 compound treatment 0.22 -0.00425 -0.06 0.245 0.0257 0.43 0.2625 0.6017 3122685 ChemDiv3_012711 COc1ccc(cc1)S(=O)(=O)n2c(SCc3ccc(cc3)C(F)(F)F)nc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B18 compound treatment 0.238 0.0138 0.2 0.212 -0.00726 -0.12 0.0529 0.2288 1214948 ChemDiv3_012712 CCC(Cc1ccccc1)NC(=O)c2c[nH]c3ccc(cc3c2=O)S(=O)(=O)N4CCC(C)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B19 compound treatment 0.235 0.0107 0.15 0.219 -2.58E-4 0.0 0.1057 0.6869 3036073 ChemDiv3_012713 Cc1cc(=O)oc2c3C(=O)/C(=C\C=C\c4ccccc4)/Oc3ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B20 compound treatment 0.252 0.0278 0.4 0.261 0.0417 0.7 0.7761 0.9638 1737086 ChemDiv3_012714 CCOc1ccc(cc1)n2c(C)nc3cc(ccc23)C(=O)NCc4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B21 compound treatment 0.224 -2.5E-4 0.0 0.249 0.0297 0.5 0.3505 0.702 1343786 ChemDiv3_012715 Cc1ccc(cc1)c2nc(NCCC3=CCCCC3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B22 compound treatment 0.28 0.0558 0.8 0.218 -0.00126 -0.02 0.5489 0.6881 1185282 ChemDiv3_012716 CC1CCCCN1S(=O)(=O)c2ccc(F)c(c2)C(=O)Nc3c(F)cc(F)cc3Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B23 mock treatment 0.253 0.0288 0.41 0.237 0.0177 0.3 0.5013 0.9874 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 B24 mock treatment 0.218 -0.00625 -0.09 0.242 0.0227 0.38 0.2067 0.5272 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C01 compound treatment 0.246 0.0217 0.31 0.222 0.00274 0.05 0.2525 0.803 3036076 ChemDiv3_012717 NC(=O)CSc1nc2cc3OCOc3cc2c(=O)n1CCCC(=O)NCc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C02 compound treatment 0.239 0.0147 0.21 0.212 -0.00726 -0.12 0.063 0.2588 3122686 ChemDiv3_012718 CCOC(=O)N1CCC(CC1)n2c(SCc3ccc(F)cc3Cl)nc4ccsc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C03 compound treatment 0.234 0.00975 0.14 0.246 0.0267 0.45 0.416 0.8851 3122687 ChemDiv3_012719 CCCCn1c(SCC(=O)Nc2ccc(OC)cc2)nc3ccc(cc3c1=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C04 compound treatment 0.253 0.0288 0.41 0.241 0.0217 0.36 0.5488 0.9982 3036077 ChemDiv3_012720 CCC(Sc1nc2ccsc2c(=O)n1NC(=O)c3ccccc3)C(=O)Nc4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C05 compound treatment 0.254 0.0297 0.43 0.242 0.0227 0.38 0.5708 0.9985 3122876 ChemDiv3_012721 O=C(NCCN1CCOCC1)C2CCC(Cn3c(=O)c4ccccc4[nH]c3=S)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C06 compound treatment 0.047 -0.177 -2.54 0.25 0.0307 0.52 -1.4279 -0.5519 1324896 ChemDiv3_012722 CN(Cc1ccccc1)C(=O)CSc2nc(NCc3ccc(Cl)cc3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C07 compound treatment 0.232 0.00775 0.11 0.217 -0.00226 -0.04 0.0516 0.4403 3122877 ChemDiv3_012723 CCOC(=O)c1sc2nc(SCC(=O)c3ccc(Br)cc3)n(N)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C08 compound treatment 0.087 -0.137 -1.96 0.228 0.00874 0.15 -1.2844 -0.6524 3122878 ChemDiv3_012724 Clc1ccc(cc1)C(=O)CSc2nc(Nc3ccc4OCOc4c3)c5ccccc5n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C09 compound treatment 0.198 -0.0262 -0.38 0.04 -0.179 -3.01 -2.3929 -0.7892 3036078 ChemDiv3_012725 O=C(NCCc1ccccc1)c2sc(=S)n3c2[nH]c(=O)c4ccccc43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C10 compound treatment 0.248 0.0238 0.34 0.04 -0.179 -3.01 -1.8872 -0.6233 3122879 ChemDiv3_012726 CN(C)C(=O)c1sc2n(CC(=O)N)c(=O)n(c3ccccc3C(F)(F)F)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C11 compound treatment 0.25 0.0257 0.37 0.228 0.00874 0.15 0.3642 0.9186 1410927 ChemDiv3_012727 COC(=O)c1ccc2c(=O)n(C3CCCCC3C)c(=S)[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C12 compound treatment 0.223 -0.00125 -0.02 0.046 -0.173 -2.91 -2.0689 -0.7114 3122880 ChemDiv3_012728 Clc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc4nc5ccccc5c(=O)n4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C13 compound treatment 0.202 -0.0222 -0.32 0.229 0.00974 0.16 -0.1094 -0.3058 1565253 ChemDiv3_012729 CC1CC(C)CN(C1)C(=O)c2ccc(cc2)n3c(=O)c4ccccc4[nH]c3=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C14 compound treatment 0.24 0.0158 0.23 0.229 0.00974 0.16 0.2749 0.9876 1492002 ChemDiv3_012730 CCCCc1ccc(Nc2ncnc3n(ncc23)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C15 compound treatment 0.207 -0.0173 -0.25 0.203 -0.0163 -0.27 -0.3674 -0.9987 3122881 ChemDiv3_012731 COc1ccccc1Cn2c(=O)c3ccc(cc3[nH]c2=S)C(=O)NCCN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C16 compound treatment 0.042 -0.182 -2.61 0.045 -0.174 -2.92 -3.9114 -0.9984 1682096 ChemDiv3_012732 CN(Cc1ccccc1)c2ncnc3n(ncc23)c4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C17 compound treatment 0.194 -0.0302 -0.43 0.237 0.0177 0.3 -0.0954 -0.1816 1728184 ChemDiv3_012733 COCCn1c(SCC(=O)NCc2ccccc2Cl)nc3cc(ccc3c1=O)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C18 compound treatment 0.24 0.0158 0.23 0.233 0.0137 0.23 0.3224 0.9999 1591478 ChemDiv3_012734 COc1ccc(cc1)n2cc(c3ccccc3)c4c(Nc5ccccc5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C19 compound treatment 0.044 -0.18 -2.58 0.278 0.0587 0.99 -1.1259 -0.4079 1682510 ChemDiv3_012735 CCC(C)NC(=O)CSc1nc2ccsc2c(=O)n1Cc3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C20 compound treatment 0.134 -0.0902 -1.29 0.046 -0.173 -2.91 -2.9691 -0.9332 1601331 ChemDiv3_012736 COC(CNc1ncnc2n(cc(c3ccccc3)c12)c4ccc(C)cc4)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C21 compound treatment 0.244 0.0198 0.28 0.207 -0.0123 -0.21 0.0543 0.1553 3036081 ChemDiv3_012737 COC(=O)c1ccccc1NC(=O)CSc2nc3ccsc3c(=O)n2c4ccc(C)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C22 compound treatment 0.232 0.00775 0.11 0.152 -0.0673 -1.13 -0.7198 -0.6346 1414331 ChemDiv3_012738 COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)C(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C23 mock treatment 0.232 0.00775 0.11 0.041 -0.178 -2.99 -2.0372 -0.6804 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 C24 mock treatment 0.188 -0.0362 -0.52 0.212 -0.00726 -0.12 -0.4528 -0.8501 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D01 compound treatment 0.28 0.0558 0.8 0.262 0.0427 0.72 1.0711 0.9986 1202420 ChemDiv3_012739 COC(=O)c1c(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3C)sc4CN(C)CCc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D02 compound treatment 0.13 -0.0943 -1.35 0.144 -0.0753 -1.26 -1.8464 -0.9995 3036082 ChemDiv3_012740 CC1CCCC(C1C)n2cnc3cc(ccc23)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D03 compound treatment 0.304 0.0798 1.14 0.335 0.116 1.94 2.1802 0.9678 3036083 ChemDiv3_012741 CC(SC1=NN2CCCC(=O)N=C2S1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D04 compound treatment 0.29 0.0658 0.94 0.292 0.0727 1.22 1.5283 0.9917 3122882 ChemDiv3_012742 Cc1oc(c2cccc(C)c2)[n+]([O-])c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D05 compound treatment 0.288 0.0638 0.91 0.256 0.0367 0.62 1.0808 0.9819 1431815 ChemDiv3_012743 Cc1ccccc1Cn2cc(SCC(=O)N3CCCc4ccccc34)c5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D06 compound treatment 0.216 -0.00825 -0.12 0.318 0.0987 1.66 1.0884 0.6551 3036085 ChemDiv3_012744 COC(=O)c1ccc(CSc2ccccc2C)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D07 compound treatment 0.225 7.5E-4 0.01 0.156 -0.0633 -1.06 -0.7432 -0.6999 3036087 ChemDiv3_012745 Brc1ccc(CSc2c[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D08 compound treatment 0.232 0.00775 0.11 0.227 0.00774 0.13 0.1703 0.9969 3122883 ChemDiv3_012746 CCn1cc(C(=O)O)c(=O)c2cc(ccc12)S(=O)(=O)N(C)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D09 compound treatment 0.183 -0.0413 -0.59 0.23 0.0107 0.18 -0.2897 -0.4696 3122884 ChemDiv3_012747 COc1ccc(cc1OC)c2cnnn2c3ccc(NC(=O)c4ccccc4C(F)(F)F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D10 compound treatment 0.299 0.0747 1.07 0.27 0.0507 0.85 1.3582 0.9936 3036088 ChemDiv3_012748 CCOC(=O)Cn1c2CCCCc2c(cc1=O)c3ccccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D11 compound treatment 0.269 0.0447 0.64 0.243 0.0237 0.4 0.7344 0.974 1507388 ChemDiv3_012749 CCNC(=S)N1CCn2cccc2C1c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D12 compound treatment 0.298 0.0737 1.05 0.233 0.0137 0.23 0.909 0.8418 3036089 ChemDiv3_012750 Clc1ccc(CC2=NCCN2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D13 compound treatment 0.238 0.0138 0.2 0.267 0.0477 0.8 0.7057 0.8553 1386056 ChemDiv3_012751 Fc1ccc(cc1)c2cc(C(=O)NCc3ccc(Cl)cc3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D14 compound treatment 0.287 0.0628 0.9 0.322 0.103 1.72 1.854 0.9537 3036091 ChemDiv3_012752 CC1=C(SCCO1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D15 compound treatment 0.293 0.0688 0.98 0.277 0.0577 0.97 1.3806 1.0 1693359 ChemDiv3_012753 Cc1ccc2sc(nc2c1)c3ccc(cc3)N4C(=O)C5CC=CCC5C4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D16 compound treatment 0.244 0.0198 0.28 0.23 0.0107 0.18 0.3272 0.9765 1432228 ChemDiv3_012754 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(ccc2F)S(=O)(=O)N(CC)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D17 compound treatment 0.313 0.0887 1.27 0.253 0.0337 0.57 1.2981 0.9338 1162689 ChemDiv3_012755 Cc1cc(C)c(c(C)c1)S(=O)(=O)n2c(SCC(=O)NC3CCCCC3)nc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D18 compound treatment 0.249 0.0248 0.35 0.295 0.0757 1.27 1.1492 0.8709 1527862 ChemDiv3_012756 CN(C1CCCCC1)C(=O)c2c[nH]c3ccc(cc3c2=O)S(=O)(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D19 compound treatment 0.279 0.0548 0.78 0.273 0.0537 0.9 1.1916 0.9975 1391891 ChemDiv3_012757 CCn1cc(C(=O)Nc2ccc(OC)cc2)c(=O)c3ccc(C)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D20 compound treatment 0.254 0.0297 0.43 0.226 0.00674 0.11 0.3809 0.8651 1486561 ChemDiv3_012758 CCc1ccc(NC(=O)c2ccc(F)c(c2)S(=O)(=O)NCC3COc4ccccc4O3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D21 compound treatment 0.3 0.0757 1.08 0.27 0.0507 0.85 1.3684 0.9929 3036551 ChemDiv3_012759 COc1ccc(Cl)cc1NC=C2C(=O)OC3(CCCCC3)OC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D22 compound treatment 0.274 0.0498 0.71 0.275 0.0557 0.94 1.1647 0.9909 1541065 ChemDiv3_012760 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(F)c(c2)C(=O)Nc3cccc(F)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D23 mock treatment 0.258 0.0338 0.48 0.255 0.0357 0.6 0.7655 0.9942 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 D24 mock treatment 0.241 0.0168 0.24 0.206 -0.0133 -0.22 0.0121 0.0369 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E01 compound treatment 0.272 0.0478 0.68 0.241 0.0217 0.36 0.741 0.9569 3036552 ChemDiv3_012761 CCN(CC)C(=O)CSc1nc2cc3OCOc3cc2c(=O)n1Cc4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E02 compound treatment 0.235 0.0107 0.15 0.249 0.0297 0.5 0.4617 0.8839 3122885 ChemDiv3_012762 Brc1ccc2nc(CSc3nc4ccsc4c(=O)n3C5CC5)cc(=O)n2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E03 compound treatment 0.244 0.0198 0.28 0.266 0.0467 0.78 0.7545 0.9049 3122886 ChemDiv3_012763 CS(=O)(=O)N(Cc1cccc(F)c1)n2c(SCc3cccc(F)c3)nc4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E04 compound treatment 0.237 0.0127 0.18 0.243 0.0237 0.4 0.4107 0.9372 3036554 ChemDiv3_012764 O=c1n(CC2CCCO2)c(=S)[nH]c3ccsc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E05 compound treatment 0.299 0.0747 1.07 0.245 0.0257 0.43 1.0615 0.9205 3122887 ChemDiv3_012765 CCOc1cc2[nH]c(=S)n(CCCCC(=O)NC3CCCCC3)c(=O)c2cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E06 compound treatment 0.269 0.0447 0.64 0.264 0.0447 0.75 0.9836 0.9968 3036555 ChemDiv3_012766 Cc1ccc(CNC(=O)CSc2nc(NCCc3ccccc3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E07 compound treatment 0.286 0.0617 0.88 0.236 0.0167 0.28 0.8232 0.8882 3123079 ChemDiv3_012767 COC(=O)c1sc2nc(SCc3ccccc3C)n(N)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E08 compound treatment 0.257 0.0328 0.47 0.246 0.0267 0.45 0.6486 0.9998 3036557 ChemDiv3_012768 CCCCC(CC)CNc1nc(=S)[nH]c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E09 compound treatment 0.306 0.0818 1.17 0.288 0.0687 1.15 1.6427 1.0 3123080 ChemDiv3_012769 O=c1n(c(SCc2ccccc2)nc3n(Cc4ccco4)c(=S)sc13)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E10 compound treatment 0.223 -0.00125 -0.02 0.297 0.0777 1.3 0.91 0.6974 3123081 ChemDiv3_012770 CN(C)C(=O)c1sc2n(Cc3ccccc3C#N)c(=O)n(Cc4ccccc4)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E11 compound treatment 0.244 0.0198 0.28 0.197 -0.0223 -0.37 -0.0644 -0.1375 1677408 ChemDiv3_012771 COc1ccc(CCn2c(=O)c3cc(Cl)ccc3[nH]c2=S)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E12 compound treatment 0.249 0.0248 0.35 0.248 0.0287 0.48 0.5914 0.9884 3123082 ChemDiv3_012772 Clc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCNc4ccc5ccccc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E13 compound treatment 0.249 0.0248 0.35 0.245 0.0257 0.43 0.5558 0.9951 1705315 ChemDiv3_012773 Clc1ccc2c(=O)n(c3cccc(c3)C(=O)NC4CCCCC4)c(=S)[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E14 compound treatment 0.272 0.0478 0.68 0.286 0.0667 1.12 1.2751 0.9718 1430393 ChemDiv3_012774 COc1ccccc1Nc2ncnc3n(ncc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E15 compound treatment 0.22 -0.00425 -0.06 0.17 -0.0493 -0.83 -0.6276 -0.7571 1680168 ChemDiv3_012775 COc1ccccc1Cn2c(=O)c3ccc(cc3[nH]c2=S)C(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E16 compound treatment 0.175 -0.0493 -0.7 0.174 -0.0453 -0.76 -1.0353 -0.9993 1483876 ChemDiv3_012776 CCN(c1cccc(C)c1)c2ncnc3n(ncc23)c4ccc(C)cc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E17 compound treatment 0.282 0.0578 0.83 0.254 0.0347 0.58 0.9964 0.9855 1388160 ChemDiv3_012777 Fc1cccc(CSc2nc3cc(ccc3c(=O)n2C4CCCCC4)C(=O)NCc5ccco5)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E18 compound treatment 0.268 0.0437 0.63 0.166 -0.0533 -0.89 -0.1896 -0.1737 1206158 ChemDiv3_012778 Cc1cccc(c1)n2cc(c3ccccc3)c4c(NCC=C)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E19 compound treatment 0.277 0.0527 0.75 0.297 0.0777 1.3 1.4562 0.9661 3123083 ChemDiv3_012779 CCCN(CCC)C(=O)CSc1nc2ccsc2c(=O)n1c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E20 compound treatment 0.271 0.0468 0.67 0.261 0.0417 0.7 0.9682 0.9997 1306755 ChemDiv3_012780 Cc1ccc(cc1)n2cc(c3ccccc3)c4c(NCc5ccccc5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E21 compound treatment 0.221 -0.00325 -0.05 0.257 0.0377 0.63 0.4151 0.6535 3123084 ChemDiv3_012781 O=c1n(CCc2ccccc2)c(SCc3ccccc3)nc4ccsc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E22 compound treatment 0.228 0.00375 0.05 0.271 0.0517 0.87 0.652 0.7494 1136867 ChemDiv3_012782 CCCC(=O)N1CCc2cc(OC)c(OC)cc2C1COc3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E23 mock treatment 0.219 -0.00525 -0.08 0.213 -0.00626 -0.11 -0.1274 -0.9865 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 E24 mock treatment 0.222 -0.00225 -0.03 0.217 -0.00226 -0.04 -0.0496 -0.9967 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F01 compound treatment 0.28 0.0558 0.8 0.233 0.0137 0.23 0.727 0.8757 1467206 ChemDiv3_012783 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)CCC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F02 compound treatment 0.232 0.00775 0.11 0.238 0.0187 0.31 0.3008 0.9019 3123085 ChemDiv3_012784 OC(=O)CN1CCN(Cc2ccccc2)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F03 compound treatment 0.261 0.0367 0.53 0.267 0.0477 0.8 0.9383 0.9791 3036635 ChemDiv3_012785 O=C(CSC1=NN2CCCC(=O)N=C2S1)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F04 compound treatment 0.273 0.0488 0.7 0.286 0.0667 1.12 1.2852 0.974 3123086 ChemDiv3_012786 CC1N=C(c2ccccc2)c3cc(Br)ccc3NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F05 compound treatment 0.324 0.0998 1.43 0.33 0.111 1.86 2.3232 0.9915 1231418 ChemDiv3_012787 COc1ccc(NC(=O)CSc2cn(Cc3ccc(Cl)cc3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F06 compound treatment 0.3 0.0757 1.08 0.306 0.0867 1.46 1.7956 0.9894 3036638 ChemDiv3_012788 OC(=O)c1ccc(CS(=O)(=O)c2ccccc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F07 compound treatment 0.135 -0.0892 -1.28 0.136 -0.0833 -1.4 -1.8908 -0.999 3036639 ChemDiv3_012789 FC(F)(F)c1ccc(CSc2c[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F08 compound treatment 0.318 0.0938 1.34 0.315 0.0957 1.61 2.0845 0.996 3123087 ChemDiv3_012790 CCn1cc(C(=O)O)c(=O)c2cc(ccc12)S(=O)(=O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F09 compound treatment 0.176 -0.0483 -0.69 0.173 -0.0463 -0.78 -1.037 -0.9983 1130174 ChemDiv3_012791 Fc1ccc(cc1)C2N(CCn3cccc23)C(=S)Nc4cccc(F)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F10 compound treatment 0.285 0.0607 0.87 0.282 0.0627 1.05 1.3591 0.9954 3123088 ChemDiv3_012792 COc1ccccc1c2cc(=O)n(CC(=O)O)c3CCCCc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F11 compound treatment 0.177 -0.0473 -0.68 0.158 -0.0613 -1.03 -1.2049 -0.9793 3123089 ChemDiv3_012793 FC(F)(F)c1cccc(NC(=S)N2CCn3cccc3C2c4cccnc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F12 compound treatment 0.254 0.0297 0.43 0.316 0.0967 1.62 1.449 0.8633 3035533 ChemDiv3_012794 OC(=O)c1ccc(CNCc2ccccc2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F13 compound treatment 0.294 0.0698 1.0 0.306 0.0867 1.46 1.7349 0.983 1425846 ChemDiv3_012795 COC(=O)CNC(=O)c1cc(nc2ccccc12)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F14 compound treatment 0.27 0.0457 0.65 0.254 0.0347 0.58 0.875 0.9983 3123090 ChemDiv3_012796 COc1ccc(CNC(=S)Nc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F15 compound treatment 0.299 0.0747 1.07 0.3 0.0807 1.36 1.7143 0.9931 1222880 ChemDiv3_012797 O=C1C2CC=CCC2C(=O)N1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F16 compound treatment 0.271 0.0468 0.67 0.292 0.0727 1.22 1.3361 0.9599 1624876 ChemDiv3_012798 Fc1ccc(cc1C(=O)N2CCC3(CC2)OCCO3)S(=O)(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F17 compound treatment 0.3 0.0757 1.08 0.273 0.0537 0.9 1.404 0.9958 1405687 ChemDiv3_012799 Clc1ccc(cc1)S(=O)(=O)n2c(SCC(=O)NCCc3ccccc3)nc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F18 compound treatment 0.066 -0.158 -2.26 0.065 -0.154 -2.59 -3.4313 -0.9978 1237900 ChemDiv3_012800 Cc1ccccc1n2c(SCC(=O)c3ccc(Cl)cc3)nc4n[nH]cc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F19 compound treatment 0.301 0.0767 1.1 0.304 0.0847 1.42 1.782 0.9918 1195849 ChemDiv3_012801 CCn1cc(C(=O)NC2CCCCCC2)c(=O)c3ccc(C)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F20 compound treatment 0.321 0.0968 1.38 0.283 0.0637 1.07 1.735 0.9919 1567000 ChemDiv3_012802 Fc1ccc(CNS(=O)(=O)c2ccc(F)c(c2)C(=O)Nc3ccc(F)c(F)c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F21 compound treatment 0.272 0.0478 0.68 0.274 0.0547 0.92 1.1326 0.9893 3035540 ChemDiv3_012803 FC(F)(F)c1cc(Cl)ccc1NC=C2C(=O)OC3(CCCCC3)OC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F22 compound treatment 0.267 0.0428 0.61 0.193 -0.0263 -0.44 0.1208 0.1602 1597221 ChemDiv3_012804 Fc1cccc(NC(=O)c2cc(ccc2F)S(=O)(=O)NCCc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F23 mock treatment 0.27 0.0457 0.65 0.219 -2.58E-4 0.0 0.4597 0.7024 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 F24 mock treatment 0.206 -0.0182 -0.26 0.2 -0.0193 -0.32 -0.4131 -0.9944 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G01 compound treatment 0.268 0.0437 0.63 0.238 0.0187 0.31 0.6649 0.9494 3123091 ChemDiv3_012805 Clc1ccc(cc1)N2CCN(CC2)C(=O)C3CCC(Cn4c(=O)c5ccccc5[nH]c4=S)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G02 compound treatment 0.22 -0.00425 -0.06 0.229 0.00974 0.16 0.0726 0.4164 3035544 ChemDiv3_012806 O=C(CCn1c(=O)c2sccc2[nH]c1=S)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G03 compound treatment 0.286 0.0617 0.88 0.273 0.0537 0.9 1.2624 0.9999 3035548 ChemDiv3_012807 CCOc1cc2[nH]c(=S)n(CCCC(=O)O)c(=O)c2cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G04 compound treatment 0.268 0.0437 0.63 0.304 0.0847 1.42 1.4482 0.932 1616439 ChemDiv3_012808 COC(CNC(=O)c1ccc(Cn2nnc3ccccc3c2=O)cc1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G05 compound treatment 0.268 0.0437 0.63 0.239 0.0197 0.33 0.6768 0.9558 3123092 ChemDiv3_012809 CCOc1cc2[nH]c(=S)n(CCCCC(=O)N3CCCCCC3)c(=O)c2cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G06 compound treatment 0.298 0.0737 1.05 0.31 0.0907 1.52 1.8229 0.9839 3035605 ChemDiv3_012810 Clc1ccccc1CCNc2nc(=S)[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G07 compound treatment 0.262 0.0377 0.54 0.292 0.0727 1.22 1.2451 0.9327 1266788 ChemDiv3_012811 CC(C)(C)C(=O)CSc1nc2n(CCc3ccccc3)c(=S)sc2c(=O)n1Cc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G08 compound treatment 0.185 -0.0393 -0.56 0.152 -0.0673 -1.13 -1.1952 -0.948 3035607 ChemDiv3_012812 COc1cc(Nc2nc(SCC(=O)c3ccc(O)c(O)c3)nc4ccccc24)cc(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G09 compound treatment 0.28 0.0558 0.8 0.245 0.0257 0.43 0.8694 0.9586 3123285 ChemDiv3_012813 COC(=O)c1sc(=S)n(c1N)c2cccc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G10 compound treatment 0.327 0.103 1.47 0.281 0.0617 1.04 1.772 0.9854 3123286 ChemDiv3_012814 NC(=O)C1CCN(CC1)C2CCN(CC2)C(=O)c3cccn4c(=O)c5ccc(Cl)cc5nc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G11 compound treatment 0.215 -0.00925 -0.13 0.218 -0.00126 -0.02 -0.1085 -0.8097 1224390 ChemDiv3_012815 CCCNC(=O)c1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G12 compound treatment 0.298 0.0737 1.05 0.287 0.0677 1.14 1.5499 0.9993 3123287 ChemDiv3_012816 COc1ccc(CCNC(=O)c2ccc3nc4ccc(Cl)cc4c(=O)n3c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G13 compound treatment 0.247 0.0227 0.33 0.218 -0.00126 -0.02 0.2152 0.6598 1549323 ChemDiv3_012817 CC(C)CCNC(=O)c1ccc2c(=O)n(Cc3ccc(Cl)cc3)c(=S)[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G14 compound treatment 0.272 0.0478 0.68 0.286 0.0667 1.12 1.2751 0.9718 1637286 ChemDiv3_012818 CCCN(CCC)c1ncnc2n(ncc12)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G15 compound treatment 0.203 -0.0213 -0.3 0.209 -0.0103 -0.17 -0.3367 -0.9638 1223545 ChemDiv3_012819 COc1ccc(CCNC(=O)c2ccc3c(=O)n(CCC4=CCCCC4)c(=S)[nH]c3c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G16 compound treatment 0.282 0.0578 0.83 0.285 0.0657 1.1 1.3643 0.9898 3035613 ChemDiv3_012820 OC1(C[N+](=C2SCCCN21)c3ccccc3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G17 compound treatment 0.249 0.0248 0.35 0.264 0.0447 0.75 0.7813 0.9411 1205107 ChemDiv3_012821 NC(=O)C1CCN(CC1)C(=O)c2ccc3c(=O)n(CC=C)c(SCc4ccc(Cl)cc4)nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G18 compound treatment 0.228 0.00375 0.05 0.239 0.0197 0.33 0.2722 0.811 1343443 ChemDiv3_012822 CC(=O)Nc1ccc(Nc2ncnc3n(cc(c4ccccc4)c23)c5cccc(C)c5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G19 compound treatment 0.252 0.0278 0.4 0.238 0.0187 0.31 0.5031 0.9934 3123288 ChemDiv3_012823 Cc1ccc(NC(=O)CSc2nc3ccsc3c(=O)n2Cc4ccccc4F)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G20 compound treatment 0.281 0.0568 0.81 0.257 0.0377 0.63 1.0219 0.9925 1495315 ChemDiv3_012824 CCOc1ccc(cc1)n2cc(c3ccccc3)c4c(NC(C)C)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G21 compound treatment 0.257 0.0328 0.47 0.248 0.0287 0.48 0.6724 0.9999 3123289 ChemDiv3_012825 Cc1ccc(NC(=O)CCCn2c(=O)c3sccc3[nH]c2=S)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G22 compound treatment 0.198 -0.0262 -0.38 0.188 -0.0313 -0.52 -0.6365 -0.9865 3035687 ChemDiv3_012826 COc1cc2CCN(C(COc3cccc(c3)C(F)(F)F)c2cc1OC)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G23 mock treatment 0.23 0.00575 0.08 0.213 -0.00626 -0.11 -0.0161 -0.1208 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 G24 mock treatment 0.224 -2.5E-4 0.0 0.207 -0.0123 -0.21 -0.148 -0.7193 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H01 compound treatment 0.224 -2.5E-4 0.0 0.236 0.0167 0.28 0.1962 0.6981 3123290 ChemDiv3_012827 COc1ccc(/C=C\C(=O)Nc2c3CSCc3nn2c4cccc(Cl)c4)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H02 compound treatment 0.249 0.0248 0.35 0.234 0.0147 0.25 0.4253 0.9847 3035690 ChemDiv3_012828 CCc1ccc(Nc2cc(C(=O)O)c3ccccc3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H03 compound treatment 0.278 0.0537 0.77 0.261 0.0417 0.7 1.039 0.9989 3123291 ChemDiv3_012829 CCCN(CCC)CN1N2CCCC(=O)N=C2SC1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H04 compound treatment 0.234 0.00975 0.14 0.227 0.00774 0.13 0.1905 0.9994 3123292 ChemDiv3_012830 O=C(N1CCc2ccccc2C1)c3ccc4Sc5ccccc5C(=O)Nc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H05 compound treatment 0.262 0.0377 0.54 0.25 0.0307 0.52 0.7467 0.9997 1475413 ChemDiv3_012831 CCOC(=O)CSc1cn(Cc2ccc(Cl)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H06 compound treatment 0.296 0.0717 1.03 0.275 0.0557 0.94 1.3872 0.9989 3123293 ChemDiv3_012832 CC1=Nc2cc(ccc2Sc3ccc(Br)cc13)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H07 compound treatment 0.278 0.0537 0.77 0.287 0.0677 1.14 1.3476 0.9818 3035696 ChemDiv3_012833 COc1cccc(c1)C(=O)Nc2ccc(cc2)n3nncc3C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H08 compound treatment 0.315 0.0907 1.3 0.265 0.0457 0.77 1.4607 0.9686 3123294 ChemDiv3_012834 Cc1oc(nc1CSCC(=O)O)c2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H09 compound treatment 0.271 0.0468 0.67 0.246 0.0267 0.45 0.7902 0.9812 1383351 ChemDiv3_012835 CCOc1ccc(NC(=S)N2CCn3cccc3C2c4ccc(OC)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H10 compound treatment 0.289 0.0648 0.93 0.303 0.0837 1.41 1.6488 0.9795 3035760 ChemDiv3_012836 OC(=O)CCC(=O)N1CCOc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H11 compound treatment 0.067 -0.157 -2.25 0.069 -0.15 -2.52 -3.3737 -0.9984 1090057 ChemDiv3_012837 CCN1CSC(=S)N(Cc2ccccc2)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H12 compound treatment 0.306 0.0818 1.17 0.276 0.0567 0.95 1.5003 0.9948 1517623 ChemDiv3_012838 N#Cc1c(sc2CCCCc12)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H13 compound treatment 0.309 0.0848 1.21 0.251 0.0317 0.53 1.2339 0.9318 1139449 ChemDiv3_012839 COc1ccc(cc1)c2cc(C(=O)Nc3cc(Cl)ccc3OC)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H14 compound treatment 0.172 -0.0522 -0.75 0.155 -0.0643 -1.08 -1.2911 -0.9839 1398409 ChemDiv3_012840 Clc1ccc(CCNC(=S)Nc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H15 compound treatment 0.306 0.0818 1.17 0.305 0.0857 1.44 1.8444 0.9947 1322442 ChemDiv3_012841 CSc1ccccc1N2C(=O)C3CC=CCC3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H16 compound treatment 0.287 0.0628 0.9 0.296 0.0767 1.29 1.5454 0.9844 1293097 ChemDiv3_012842 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(F)c(c2)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H17 compound treatment 0.311 0.0867 1.24 0.339 0.12 2.01 2.2985 0.9731 1480085 ChemDiv3_012843 CN(C1CCCCC1)C(=O)c2cccc(c2)N3C(=O)C4C5CC(C=C5)C4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H18 compound treatment 0.256 0.0318 0.45 0.3 0.0807 1.36 1.2794 0.8951 3035768 ChemDiv3_012844 OC(=O)/C=C/C(=O)NC1CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H19 compound treatment 0.312 0.0877 1.26 0.282 0.0627 1.05 1.6322 0.9962 1617005 ChemDiv3_012845 CCCCN(C)C(=O)c1cn(CC)c2nc(C)ccc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H20 compound treatment 0.213 -0.0113 -0.16 0.255 0.0357 0.6 0.3104 0.4998 1584474 ChemDiv3_012846 Fc1cccc(NC(=O)c2cc(ccc2F)S(=O)(=O)N3CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H21 compound treatment 0.277 0.0527 0.75 0.29 0.0707 1.19 1.3731 0.976 3035772 ChemDiv3_012847 O=C1OC2(CCCCC2)OC(=O)C1=CNc3nccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H22 compound treatment 0.263 0.0388 0.55 0.262 0.0427 0.72 0.8992 0.9919 1697267 ChemDiv3_012848 Fc1ccc(cc1C(=O)Nc2cc(Cl)cc(Cl)c2)S(=O)(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H23 mock treatment 0.24 0.0158 0.23 0.236 0.0167 0.28 0.358 0.994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 H24 mock treatment 0.204 -0.0203 -0.29 0.199 -0.0203 -0.34 -0.4452 -0.9968 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I01 compound treatment 0.252 0.0278 0.4 0.267 0.0477 0.8 0.8473 0.9475 3035832 ChemDiv3_012849 O=c1n(CCc2ccccc2)c(=S)[nH]c3ccc(cc13)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I02 compound treatment 0.268 0.0437 0.63 0.23 0.0107 0.18 0.57 0.8752 3123295 ChemDiv3_012850 Clc1ccc(CCNC(=O)CCn2c(=O)c3sccc3[nH]c2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I03 compound treatment 0.289 0.0648 0.93 0.277 0.0577 0.97 1.3402 0.9997 3123296 ChemDiv3_012851 O=c1n(CCCn2c(SCC#N)nc3ccccc3c2=O)c(SCC#N)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I04 compound treatment 0.271 0.0468 0.67 0.23 0.0107 0.18 0.6003 0.8668 3035835 ChemDiv3_012852 CC1CCCCN1CCNc2nc(=S)[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I05 compound treatment 0.231 0.00675 0.1 0.203 -0.0163 -0.27 -0.1247 -0.4307 3123297 ChemDiv3_012853 CCCCN(C)C(=O)Cc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I06 compound treatment 0.245 0.0208 0.3 0.263 0.0437 0.73 0.729 0.9206 3035838 ChemDiv3_012854 S=c1nc(NC2CC2)c3ccccc3[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I07 compound treatment 0.258 0.0338 0.48 0.274 0.0547 0.92 0.991 0.9549 3123298 ChemDiv3_012855 COc1cccc(c1)n2c(=S)sc3c(=O)n(c(SCC4OCCO4)nc23)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I08 compound treatment 0.3 0.0757 1.08 0.299 0.0797 1.34 1.7125 0.9945 3035840 ChemDiv3_012856 NC(=O)c1ccc(Nc2nc(=S)[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I09 compound treatment 0.291 0.0668 0.95 0.333 0.114 1.91 2.025 0.9487 3123299 ChemDiv3_012857 CCOC(=O)c1sc(=S)n(c1N)c2ccc(OC)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I10 compound treatment 0.301 0.0767 1.1 0.284 0.0647 1.09 1.5446 1.0 3035842 ChemDiv3_012858 Brc1ccc2nc3c(cccn3c(=O)c2c1)C(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I11 compound treatment 0.227 0.00275 0.04 0.239 0.0197 0.33 0.2621 0.7855 1739349 ChemDiv3_012859 CCCn1c(=O)c2ccc(cc2[nH]c1=S)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I12 compound treatment 0.307 0.0828 1.18 0.302 0.0827 1.39 1.8189 0.9968 3123300 ChemDiv3_012860 Clc1ccc2nc3ccc(cn3c(=O)c2c1)C(=O)NCCN4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I13 compound treatment 0.235 0.0107 0.15 0.206 -0.0133 -0.22 -0.0486 -0.1798 1601402 ChemDiv3_012861 COC(CNC(=O)c1cccc(c1)n2c(=O)c3ccc(Cl)cc3[nH]c2=S)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I14 compound treatment 0.25 0.0257 0.37 0.263 0.0437 0.73 0.7796 0.9491 1450801 ChemDiv3_012862 CCCN(CCC)c1ncnc2n(ncc12)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I15 compound treatment 0.279 0.0548 0.78 0.309 0.0897 1.51 1.6188 0.9536 1131217 ChemDiv3_012863 Fc1cccc(CSc2nc3ccccc3c(=O)n2CC4CCCO4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I16 compound treatment 0.248 0.0238 0.34 0.258 0.0387 0.65 0.7 0.9542 3120257 ChemDiv3_012864 CCc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I17 compound treatment 0.266 0.0418 0.6 0.264 0.0447 0.75 0.9533 0.9936 3035846 ChemDiv3_012865 Cc1ccccc1N2C(=O)CSC2=C(C#N)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I18 compound treatment 0.309 0.0848 1.21 0.326 0.107 1.79 2.124 0.9819 1262485 ChemDiv3_012866 COCC(C)Nc1ncnc2n(cc(c3ccccc3)c12)c4ccc(C)c(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I19 compound treatment 0.243 0.0187 0.27 0.231 0.0117 0.2 0.329 0.9885 1515194 ChemDiv3_012867 COC(=O)c1ccccc1NC(=O)CSc2nc3ccsc3c(=O)n2Cc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I20 compound treatment 0.216 -0.00825 -0.12 0.22 7.42E-4 0.01 -0.0746 -0.629 1661054 ChemDiv3_012868 CCOc1ccc(cc1)n2cc(c3ccccc3)c4c(NCC=C)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I21 compound treatment 0.234 0.00975 0.14 0.192 -0.0273 -0.46 -0.2249 -0.4702 3036011 ChemDiv3_012869 Fc1ccc(CSc2nc3ccsc3c(=O)n2NC(=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I22 compound treatment 0.181 -0.0432 -0.62 0.238 0.0187 0.31 -0.215 -0.3098 1602477 ChemDiv3_012870 COC(=O)c1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I23 mock treatment 0.209 -0.0153 -0.22 0.214 -0.00526 -0.09 -0.2166 -0.9207 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 I24 mock treatment 0.184 -0.0403 -0.58 0.213 -0.00626 -0.11 -0.4814 -0.8225 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J01 compound treatment 0.233 0.00875 0.13 0.25 0.0307 0.52 0.4533 0.8539 1624497 ChemDiv3_012871 CCCCC1CCC(CC1)C(=O)Nc2c3CS(=O)(=O)Cc3nn2c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J02 compound treatment 0.258 0.0338 0.48 0.263 0.0437 0.73 0.8605 0.9793 3120258 ChemDiv3_012872 C(NC1CCCCCC1)c2c[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J03 compound treatment 0.238 0.0138 0.2 0.248 0.0287 0.48 0.4802 0.9217 3036016 ChemDiv3_012873 O=C1CCCN2N(CN(Cc3ccccc3)Cc4ccccc4)C(=S)SC2=N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J04 compound treatment 0.287 0.0628 0.9 0.248 0.0287 0.48 0.9758 0.9576 3120259 ChemDiv3_012874 CCc1ccc(cc1)C2=NNC(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J05 compound treatment 0.271 0.0468 0.67 0.27 0.0507 0.85 1.075 0.9928 1566087 ChemDiv3_012875 CCn1cc(SCC(=O)N2N=C(CC2c3ccc(C)cc3)c4cccs4)c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J06 compound treatment 0.268 0.0437 0.63 0.266 0.0467 0.78 0.9972 0.9937 3036021 ChemDiv3_012876 COc1ccccc1S(=O)Cc2ccc(o2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J07 compound treatment 0.194 -0.0302 -0.43 0.262 0.0427 0.72 0.2013 0.2403 3120260 ChemDiv3_012877 O=C(Nc1ccc(cc1)n2nncc2c3ccccc3)/C=C/c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J08 compound treatment 0.302 0.0778 1.11 0.249 0.0297 0.5 1.1394 0.9347 3036025 ChemDiv3_012878 COC(=O)c1ccc(CS(=O)(=O)c2ccc(OC)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J09 compound treatment 0.295 0.0707 1.01 0.299 0.0797 1.34 1.662 0.9905 1444272 ChemDiv3_012879 CC(C)(C)NC(=S)N1CCn2cccc2C1c3ccccc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J10 compound treatment 0.29 0.0658 0.94 0.244 0.0247 0.42 0.9586 0.9325 3036028 ChemDiv3_012880 CC1=Nc2cc(ccc2Sc3c(C)ccc(C)c13)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J11 compound treatment 0.127 -0.0973 -1.39 0.072 -0.147 -2.47 -2.7313 -0.963 1076058 ChemDiv3_012881 CC(C)N1CSC(=S)N(Cc2ccccc2)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J12 compound treatment 0.309 0.0848 1.21 0.32 0.101 1.69 2.0528 0.9867 3036093 ChemDiv3_012882 CCOC(=O)C1CCN(CC1)C(=O)c2cnn(c2n3cccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J13 compound treatment 0.267 0.0428 0.61 0.284 0.0647 1.09 1.2007 0.963 1166978 ChemDiv3_012883 Fc1ccc(NC(=O)c2cc(nc3ccccc23)N4CCN(CC4)c5ccc(F)cc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J14 compound treatment 0.236 0.0118 0.17 0.281 0.0617 1.04 0.8516 0.8112 1351529 ChemDiv3_012884 C=CCN(C(=O)CSc1nc2[nH]ncc2c(=O)n1c3cccc4ccccc34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J15 compound treatment 0.298 0.0737 1.05 0.301 0.0817 1.37 1.716 0.9916 1509996 ChemDiv3_012885 COC(=O)c1ccccc1NC(=O)C2CCCCC2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J16 compound treatment 0.269 0.0447 0.64 0.28 0.0607 1.02 1.1735 0.9748 1120274 ChemDiv3_012886 COC(CNC(=O)c1cc(ccc1F)S(=O)(=O)N2CC(C)CC(C)C2)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J17 compound treatment 0.275 0.0508 0.73 0.304 0.0847 1.42 1.519 0.9513 1592909 ChemDiv3_012887 CC1CCCCC1NC(=O)c2cccc(c2)N3C(=O)C4C5CC(C=C5)C4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J18 compound treatment 0.263 0.0388 0.55 0.252 0.0327 0.55 0.7805 1.0 1694150 ChemDiv3_012888 CCc1ccccc1n2c(SCc3cc(=O)n4ccccc4n3)nc5[nH]ncc5c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J19 compound treatment 0.307 0.0828 1.18 0.316 0.0967 1.62 1.9851 0.9879 1549433 ChemDiv3_012889 CCN(CC)S(=O)(=O)c1ccc(Cc2ccc(cc2)S(=O)(=O)N(CC)CC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J20 compound treatment 0.259 0.0348 0.5 0.272 0.0527 0.89 0.9774 0.9628 3120261 ChemDiv3_012890 N=c1[nH]c(SCc2cc(=O)n3ccccc3n2)ncc1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J21 compound treatment 0.274 0.0498 0.71 0.257 0.0377 0.63 0.9511 0.9983 1483711 ChemDiv3_012891 O=C(CSc1ncccc1C(=O)N2CCC(Cc3ccccc3)CC2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J22 compound treatment 0.252 0.0278 0.4 0.238 0.0187 0.31 0.5031 0.9934 3036105 ChemDiv3_012892 NC(CSCc1ccccc1Cl)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J23 mock treatment 0.247 0.0227 0.33 0.235 0.0157 0.26 0.4169 0.9947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 J24 mock treatment 0.235 0.0107 0.15 0.219 -2.58E-4 0.0 0.1057 0.6869 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K01 compound treatment 0.224 -2.5E-4 0.0 0.213 -0.00626 -0.11 -0.0768 -0.7308 3120262 ChemDiv3_012893 COc1ccc(Cn2c(SCC#N)nc3ccc(cc3c2=O)N4CCOCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K02 compound treatment 0.28 0.0558 0.8 0.279 0.0597 1.0 1.2729 0.9936 3035553 ChemDiv3_012894 CCC(Sc1nc2ccsc2c(=O)n1C3CC3)C(=O)Nc4ccc(CC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K03 compound treatment 0.33 0.106 1.51 0.302 0.0827 1.39 2.0516 0.9991 3120263 ChemDiv3_012895 O=C(Cc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K04 compound treatment 0.299 0.0747 1.07 0.163 -0.0563 -0.94 0.0884 0.0619 3120264 ChemDiv3_012896 CCN(CCCNc1nc(=S)[nH]c2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K05 compound treatment 0.272 0.0478 0.68 0.234 0.0147 0.25 0.6579 0.9057 3035557 ChemDiv3_012897 CCOC(=O)c1sc2nc(SCC(=O)C(C)(C)C)n(Cc3ccccc3Cl)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K06 compound treatment 0.126 -0.0983 -1.41 0.083 -0.136 -2.29 -2.6108 -0.9727 1521442 ChemDiv3_012898 Clc1ccccc1CSc2nc(NCC3CCCO3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K07 compound treatment 0.254 0.0297 0.43 0.246 0.0267 0.45 0.6183 0.9996 3120265 ChemDiv3_012899 CCOC(=O)CSc1nc2n(c3ccccc3C)c(=S)sc2c(=O)n1c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K08 compound treatment 0.201 -0.0233 -0.33 0.207 -0.0123 -0.21 -0.3806 -0.9734 3035617 ChemDiv3_012900 Cc1ccc(CNC(=O)C2CCC(CNc3nc(=S)[nH]c4ccccc34)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K09 compound treatment 0.258 0.0338 0.48 0.31 0.0907 1.52 1.4183 0.8877 3120266 ChemDiv3_012901 COC(=O)c1sc(=S)n(c1N)c2cc(OC)ccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K10 compound treatment 0.257 0.0328 0.47 0.253 0.0337 0.57 0.7317 0.9956 3120267 ChemDiv3_012902 Brc1ccc2nc3c(cccn3c(=O)c2c1)C(=O)NC4CCCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K11 compound treatment 0.276 0.0517 0.74 0.278 0.0587 0.99 1.2206 0.99 1528121 ChemDiv3_012903 COc1ccc(CNC(=O)Cn2c(=O)c3ccccc3[nH]c2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K12 compound treatment 0.246 0.0217 0.31 0.256 0.0367 0.62 0.656 0.9498 3120268 ChemDiv3_012904 CCOC(=O)c1sc2nc3SCC(=Nn3c(=O)c2c1C)c4cc5cc(Cl)ccc5oc4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K13 compound treatment 0.262 0.0377 0.54 0.219 -2.58E-4 0.0 0.3787 0.7014 3035625 ChemDiv3_012905 O=C(N1CCNCC1)c2ccc3c(=O)n(Cc4ccc5OCOc5c4)c(=S)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K14 compound treatment 0.274 0.0498 0.71 0.292 0.0727 1.22 1.3665 0.967 1489972 ChemDiv3_012906 CC(C)CN(CC(C)C)c1ncnc2n(ncc12)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K15 compound treatment 0.284 0.0597 0.85 0.29 0.0707 1.19 1.4439 0.987 1732204 ChemDiv3_012907 CCOC(=O)CSc1nc2cc(ccc2c(=O)n1CC=C)C(=O)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K16 compound treatment 0.199 -0.0253 -0.36 0.187 -0.0323 -0.54 -0.6382 -0.9806 1721842 ChemDiv3_012908 CC(C)CNc1ncnc2n(cc(c3ccccc3)c12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K17 compound treatment 0.249 0.0248 0.35 0.232 0.0127 0.21 0.4015 0.9709 3120452 ChemDiv3_012909 Cc1ccccc1CSC(=C(C#N)C(=O)NCc2ccco2)SCc3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K18 compound treatment 0.294 0.0698 1.0 0.303 0.0837 1.41 1.6993 0.9859 1324880 ChemDiv3_012910 Cc1ccc(cc1Cl)n2cc(c3ccccc3)c4c(NN5CCOCC5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K19 compound treatment 0.281 0.0568 0.81 0.247 0.0277 0.47 0.9032 0.9652 3035701 ChemDiv3_012911 CCCCn1c(SCC(=O)c2ccccc2)nc3ccsc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K20 compound treatment 0.219 -0.00525 -0.08 0.309 0.0897 1.51 1.012 0.671 3120453 ChemDiv3_012912 FC(F)(F)c1cccc(c1)n2cc(c3ccccc3)c4c(NCC=C)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K21 compound treatment 0.235 0.0107 0.15 0.249 0.0297 0.5 0.4617 0.8839 3035705 ChemDiv3_012913 COc1ccc(NC(=O)C2CCC(Cn3c(=O)c4sccc4[nH]c3=S)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K22 compound treatment 0.251 0.0267 0.38 0.212 -0.00726 -0.12 0.1844 0.4593 1400316 ChemDiv3_012914 COc1cc2CCN(C(COc3cc(C)cc(C)c3)c2cc1OC)C(=O)Cc4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K23 mock treatment 0.224 -2.5E-4 0.0 0.208 -0.0113 -0.19 -0.1361 -0.7204 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 K24 mock treatment 0.204 -0.0203 -0.29 0.213 -0.00626 -0.11 -0.2791 -0.9058 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L01 compound treatment 0.275 0.0508 0.73 0.283 0.0637 1.07 1.2698 0.9821 1372066 ChemDiv3_012915 COc1cc(cc(OC)c1OC)C(=O)Nc2c3CS(=O)(=O)Cc3nn2c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L02 compound treatment 0.261 0.0367 0.53 0.274 0.0547 0.92 1.0214 0.9649 3035708 ChemDiv3_012916 OC(=O)c1cccc(c1)N2CCCC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L03 compound treatment 0.231 0.00675 0.1 0.251 0.0317 0.53 0.445 0.8219 3035709 ChemDiv3_012917 CC1CCN(CN2N3CCCC(=O)N=C3SC2=S)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L04 compound treatment 0.271 0.0468 0.67 0.289 0.0697 1.17 1.3005 0.9647 3120454 ChemDiv3_012918 COC(=O)c1cn(CC=C)c2ccc(cc2c1=O)S(=O)(=O)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L05 compound treatment 0.288 0.0638 0.91 0.289 0.0697 1.17 1.4725 0.9924 1237033 ChemDiv3_012919 CCCn1cc(SCC(=O)N2CCc3ccccc23)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L06 compound treatment 0.288 0.0638 0.91 0.287 0.0677 1.14 1.4487 0.994 3120455 ChemDiv3_012920 CCOC(=O)c1cn(CC)c2ccc(cc2c1=O)S(=O)(=O)N3CCc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L07 compound treatment 0.204 -0.0203 -0.29 0.261 0.0417 0.7 0.2906 0.3833 1394940 ChemDiv3_012921 Fc1cccc(F)c1C(=O)Nc2ccc(cc2)n3nncc3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L08 compound treatment 0.263 0.0388 0.55 0.309 0.0897 1.51 1.457 0.9078 3120456 ChemDiv3_012922 Cc1ccsc1c2nc(CSCC(=O)O)c(C)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L09 compound treatment 0.293 0.0688 0.98 0.308 0.0887 1.49 1.7486 0.9797 1398310 ChemDiv3_012923 COc1ccc(OC)c(c1)C2N(CCn3cccc23)C(=S)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L10 compound treatment 0.235 0.0107 0.15 0.224 0.00474 0.08 0.165 0.953 3120457 ChemDiv3_012924 Cc1ccc(cc1)C(=O)C2COC(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L11 compound treatment 0.082 -0.142 -2.03 0.1 -0.119 -2.0 -2.8541 -1.0 1569910 ChemDiv3_012925 S=C1SCN(CCN2CCOCC2)CN1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L12 compound treatment 0.291 0.0668 0.95 0.292 0.0727 1.22 1.5384 0.9926 3120458 ChemDiv3_012926 CC(C)(C)NC(=O)c1sccc1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L13 compound treatment 0.304 0.0798 1.14 0.292 0.0727 1.22 1.6699 0.9994 1726587 ChemDiv3_012927 CC1C=CCC2C1C(=O)N(C2=O)c3ccc4CCCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L14 compound treatment 0.29 0.0658 0.94 0.311 0.0917 1.54 1.7538 0.972 3035783 ChemDiv3_012928 COC(=O)c1cnn(C(=O)c2ccccc2Br)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L15 compound treatment 0.265 0.0408 0.58 0.292 0.0727 1.22 1.2755 0.9428 3120459 ChemDiv3_012929 COc1cc(cc(OC)c1OC)c2noc(n2)c3c(C)onc3c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L16 compound treatment 0.223 -0.00125 -0.02 0.256 0.0367 0.62 0.4234 0.6863 1153972 ChemDiv3_012930 COc1ccc(cc1)S(=O)(=O)NCCC(=O)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L17 compound treatment 0.272 0.0478 0.68 0.233 0.0137 0.23 0.646 0.8962 1451179 ChemDiv3_012931 O=C(NCCc1ccccc1)c2cccc(c2)N3C(=O)C4CC=CCC4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L18 compound treatment 0.285 0.0607 0.87 0.247 0.0277 0.47 0.9437 0.9572 1630411 ChemDiv3_012932 CCc1ccccc1n2c(SCC(=O)N3CCCC3)nc4[nH]ncc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L19 compound treatment 0.268 0.0437 0.63 0.288 0.0687 1.15 1.2583 0.9587 1662144 ChemDiv3_012933 O=S(=O)(N1CCCCC1)c2ccc(Cc3ccc(cc3)S(=O)(=O)N4CCCCC4)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L20 compound treatment 0.287 0.0628 0.9 0.267 0.0477 0.8 1.2013 0.9984 3036993 ChemDiv3_012934 CC(=O)N/C(=C/c1ccccc1Br)/C(=O)NCc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L21 compound treatment 0.265 0.0408 0.58 0.256 0.0367 0.62 0.8482 0.9996 1495909 ChemDiv3_012935 COc1ccc(cc1)c2nc3cc(C)ccc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L22 compound treatment 0.28 0.0558 0.8 0.219 -2.58E-4 0.0 0.5608 0.7033 1381633 ChemDiv3_012936 CC(C)c1ccc(NC(=O)c2cc(ccc2F)S(=O)(=O)N(CC=C)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L23 mock treatment 0.247 0.0227 0.33 0.221 0.00174 0.03 0.2508 0.7675 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 L24 mock treatment 0.204 -0.0203 -0.29 0.21 -0.00926 -0.16 -0.3147 -0.9574 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M01 compound treatment 0.259 0.0348 0.5 0.27 0.0507 0.85 0.9537 0.9671 3120460 ChemDiv3_012937 O=c1n(CCc2ccccc2)c(SCC#N)nc3ccc(cc13)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M02 compound treatment 0.325 0.101 1.44 0.297 0.0777 1.3 1.9417 0.9988 3036994 ChemDiv3_012938 CCn1c(SCC(=O)Nc2ccc(OC)cc2)nc3ccsc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M03 compound treatment 0.291 0.0668 0.95 0.29 0.0707 1.19 1.5147 0.9942 3120461 ChemDiv3_012939 O=C(Cc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M04 compound treatment 0.297 0.0727 1.04 0.25 0.0307 0.52 1.1007 0.9476 3036995 ChemDiv3_012940 CCC1CCCCN1CCCNc2nc(=S)[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M05 compound treatment 0.285 0.0607 0.87 0.282 0.0627 1.05 1.3591 0.9954 1713525 ChemDiv3_012941 CCOC(=O)c1sc2nc(SCc3cccc(Cl)c3)n(Cc4cccs4)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M06 compound treatment 0.314 0.0897 1.28 0.281 0.0617 1.04 1.6405 0.9944 1497467 ChemDiv3_012942 Cc1ccc(CNC(=O)CSc2nc(NC3CCCCC3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M07 compound treatment 0.274 0.0498 0.71 0.255 0.0357 0.6 0.9274 0.9964 3036996 ChemDiv3_012943 Cc1cc(ccc1Cl)n2c(=S)sc3c(=O)n(c(SCC#N)nc23)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M08 compound treatment 0.152 -0.0722 -1.03 0.126 -0.0933 -1.57 -1.8375 -0.9797 3120462 ChemDiv3_012944 Clc1cccc(CNC(=O)Cc2csc(Nc3nc(=S)[nH]c4ccccc34)n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M09 compound treatment 0.243 0.0187 0.27 0.291 0.0717 1.2 1.0411 0.8439 1871501 ChemDiv3_012945 COc1cc2[nH]c(=S)n(CCc3ccccc3)c(=O)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M10 compound treatment 0.296 0.0717 1.03 0.257 0.0377 0.63 1.1736 0.9731 3120463 ChemDiv3_012946 CCOC(=O)N1CCN(CC1)C(=O)c2cccn3c(=O)c4cc5ccccc5cc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M11 compound treatment 0.247 0.0227 0.33 0.278 0.0587 0.99 0.9273 0.8931 1644897 ChemDiv3_012947 CCCn1c(=O)c2ccc(cc2[nH]c1=S)C(=O)N3CC(C)CC(C)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M12 compound treatment 0.246 0.0217 0.31 0.215 -0.00426 -0.07 0.1694 0.5308 1480601 ChemDiv3_012948 CC(C)(C)Nc1ncnc2n(ncc12)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M13 compound treatment 0.283 0.0587 0.84 0.3 0.0807 1.36 1.5525 0.9736 3120464 ChemDiv3_012949 CN(C)CCNC(=O)c1ccc2c(=O)n(Cc3ccc4OCOc4c3)c(=S)[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M14 compound treatment 0.269 0.0447 0.64 0.252 0.0327 0.55 0.8412 0.9971 1601359 ChemDiv3_012950 CC(C)CN(CC(C)C)c1ncnc2n(ncc12)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M15 compound treatment 0.285 0.0607 0.87 0.245 0.0257 0.43 0.9199 0.948 1137565 ChemDiv3_012951 C=CCn1c(SCC(=O)N2CCCC2)nc3cc(ccc3c1=O)C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M16 compound treatment 0.254 0.0297 0.43 0.201 -0.0183 -0.31 0.0842 0.1606 3036997 ChemDiv3_012952 Clc1ccc(cc1)n2cc(c3ccccc3)c4c(NCCCN5CCOCC5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M17 compound treatment 0.226 0.00175 0.03 0.267 0.0477 0.8 0.5843 0.7288 3120465 ChemDiv3_012953 CCSC(=C(C#N)C(=O)Nc1ccccc1)SCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M18 compound treatment 0.224 -2.5E-4 0.0 0.224 0.00474 0.08 0.0537 0.6747 1271088 ChemDiv3_012954 Clc1cccc(c1)n2cc(c3ccccc3)c4c(NCC5CCCO5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M19 compound treatment 0.268 0.0437 0.63 0.232 0.0127 0.21 0.5937 0.8978 3036998 ChemDiv3_012955 CCCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc3ccsc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M20 compound treatment 0.247 0.0227 0.33 0.281 0.0617 1.04 0.9629 0.8865 1672786 ChemDiv3_012956 CCN1CCN(CC1)c2ncnc3n(cc(c4ccccc4)c23)c5ccc(Cl)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M21 compound treatment 0.267 0.0428 0.61 0.277 0.0577 0.97 1.1177 0.9753 3120466 ChemDiv3_012957 CCC(C)NC(=O)CSc1nc2ccsc2c(=O)n1NC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M22 compound treatment 0.207 -0.0173 -0.25 0.232 0.0127 0.21 -0.0232 -0.0712 1269342 ChemDiv3_012958 COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)Nc4ccc(Cl)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M23 mock treatment 0.202 -0.0222 -0.32 0.246 0.0267 0.45 0.0923 0.1678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 M24 mock treatment 0.23 0.00575 0.08 0.237 0.0177 0.3 0.2687 0.8698 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N01 compound treatment 0.287 0.0628 0.9 0.263 0.0437 0.73 1.1538 0.995 1313230 ChemDiv3_012959 Fc1ccc(cc1)n2nc3CS(=O)(=O)Cc3c2NC(=O)COc4ccc5ccccc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N02 compound treatment 0.268 0.0437 0.63 0.272 0.0527 0.89 1.0684 0.9856 3036999 ChemDiv3_012960 CCC(=O)Nc1cc(ccc1Sc2ccc(OC)cc2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N03 compound treatment 0.305 0.0808 1.16 0.252 0.0327 0.55 1.2053 0.9423 1567205 ChemDiv3_012961 COc1ccc(CCNC(=O)CSc2cn(Cc3ccc(F)cc3)c4ccccc24)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N04 compound treatment 0.272 0.0478 0.68 0.292 0.0727 1.22 1.3463 0.9623 3037000 ChemDiv3_012962 Cc1ccc(CN2CCCNC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N05 compound treatment 0.244 0.0198 0.28 0.281 0.0617 1.04 0.9325 0.8682 1421939 ChemDiv3_012963 CCCn1cc(SCC(=O)N2N=C(CC2c3ccc(OC)cc3)c4cccs4)c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N06 compound treatment 0.285 0.0607 0.87 0.279 0.0597 1.0 1.3235 0.9975 3037001 ChemDiv3_012964 CCN(CC)S(=O)(=O)c1ccc2n(CC=C)cc(C(=O)OC)c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N07 compound treatment 0.279 0.0548 0.78 0.277 0.0577 0.97 1.239 0.9944 3120648 ChemDiv3_012965 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc(cc2)n3nncc3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N08 compound treatment 0.29 0.0658 0.94 0.284 0.0647 1.09 1.4334 0.9974 3037002 ChemDiv3_012966 COc1cccc(c1)c2nc(CS(=O)CC(=O)O)c(C)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N09 compound treatment 0.275 0.0508 0.73 0.259 0.0397 0.67 0.985 0.9991 1586522 ChemDiv3_012967 S=C(NC1CCCCC1)N2CCn3cccc3C2c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N10 compound treatment 0.311 0.0867 1.24 0.259 0.0397 0.67 1.3491 0.9576 3037003 ChemDiv3_012968 CC1CCN(CC1)c2nnc(N)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N11 compound treatment 0.295 0.0707 1.01 0.309 0.0897 1.51 1.7806 0.9813 3120649 ChemDiv3_012969 CN(CCC#N)S(=O)(=O)c1ccc2[nH]cc(C(=O)O)c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N12 compound treatment 0.252 0.0278 0.4 0.28 0.0607 1.02 1.0016 0.9155 3037004 ChemDiv3_012970 OC(=O)c1nsc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N13 compound treatment 0.272 0.0478 0.68 0.304 0.0847 1.42 1.4887 0.9435 1313548 ChemDiv3_012971 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(O)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N14 compound treatment 0.307 0.0828 1.18 0.278 0.0587 0.99 1.5341 0.9959 1622154 ChemDiv3_012972 Clc1cccc(c1)N2CCN(CC2)C(=O)CCN3C(=O)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N15 compound treatment 0.264 0.0398 0.57 0.285 0.0657 1.1 1.1823 0.9525 3120650 ChemDiv3_012973 Brc1ccc(cc1)C(=O)NN2S(=O)(=O)c3ccccc3S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N16 compound treatment 0.264 0.0398 0.57 0.253 0.0337 0.57 0.8025 1.0 1382984 ChemDiv3_012974 OC(=O)CCNS(=O)(=O)c1ccc(Br)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N17 compound treatment 0.252 0.0278 0.4 0.242 0.0227 0.38 0.5506 0.9998 1368603 ChemDiv3_012975 CN(C1CCCCC1)C(=O)c2ccc3C(=O)N(CCC4=CCCCC4)C(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N18 compound treatment 0.266 0.0418 0.6 0.197 -0.0223 -0.37 0.1581 0.2245 1468722 ChemDiv3_012976 Brc1ccc(o1)C(=O)NCCC(=O)NC2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N19 compound treatment 0.261 0.0367 0.53 0.291 0.0717 1.2 1.2231 0.931 1444512 ChemDiv3_012977 CC(C)CCNS(=O)(=O)c1ccc(cc1)c2ccc(cc2)S(=O)(=O)NCCC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N20 compound treatment 0.277 0.0527 0.75 0.275 0.0557 0.94 1.1951 0.9943 3120651 ChemDiv3_012978 CC(=O)N/C(=C/c1ccccc1Br)/C(=O)NC2CCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N21 compound treatment 0.282 0.0578 0.83 0.249 0.0297 0.5 0.9371 0.9709 3037005 ChemDiv3_012979 OC(=O)c1cc(Sc2ccccc2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N22 compound treatment 0.209 -0.0153 -0.22 0.231 0.0117 0.2 -0.0149 -0.0506 1516541 ChemDiv3_012980 CCc1ccccc1NC(=O)CCSc2nc3n[nH]c(C)c3c(=N)n2c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N23 mock treatment 0.233 0.00875 0.13 0.206 -0.0133 -0.22 -0.0688 -0.2697 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 N24 mock treatment 0.252 0.0278 0.4 0.223 0.00374 0.06 0.3251 0.8089 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O01 compound treatment 0.264 0.0398 0.57 0.252 0.0327 0.55 0.7906 0.9999 3120652 ChemDiv3_012981 Fc1ccc(CSc2nc3ccc(cc3c(=O)n2CCc4ccccc4)N5CCOCC5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O02 compound treatment 0.268 0.0437 0.63 0.24 0.0207 0.35 0.6887 0.9617 3037006 ChemDiv3_012982 O=C(CSc1nc2ccsc2c(=O)n1Cc3ccccn3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O03 compound treatment 0.263 0.0388 0.55 0.247 0.0277 0.47 0.7212 0.9962 3120653 ChemDiv3_012983 O=C(Cc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O04 compound treatment 0.258 0.0338 0.48 0.271 0.0517 0.87 0.9554 0.9616 3037007 ChemDiv3_012984 Fc1ccccc1N2CCN(CCCNc3nc(=S)[nH]c4ccccc34)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O05 compound treatment 0.26 0.0357 0.51 0.27 0.0507 0.85 0.9638 0.9702 3120654 ChemDiv3_012985 CN(C)C(=O)c1sc2[nH]c(=S)n(CCc3ccc(Cl)cc3)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O06 compound treatment 0.248 0.0238 0.34 0.255 0.0357 0.6 0.6644 0.9637 1227465 ChemDiv3_012986 COc1ccc(CCNc2nc(SCC(=O)c3ccc(F)cc3)nc4ccccc24)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O07 compound treatment 0.224 -2.5E-4 0.0 0.241 0.0217 0.36 0.2555 0.7001 3037008 ChemDiv3_012987 CCc1ccc(cc1)n2c(=S)sc3c(=O)n(c(SCC#N)nc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O08 compound treatment 0.239 0.0147 0.21 0.212 -0.00726 -0.12 0.063 0.2588 3120655 ChemDiv3_012988 Clc1cccc(c1)N2CCN(CC2)C(=O)Cc3csc(Nc4nc(=S)[nH]c5ccccc45)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O09 compound treatment 0.261 0.0367 0.53 0.24 0.0207 0.35 0.6179 0.98 1071880 ChemDiv3_012989 CC(C)n1c(=O)c2ccccc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O10 compound treatment 0.242 0.0177 0.25 0.241 0.0217 0.36 0.4376 0.9843 3037009 ChemDiv3_012990 CC(C)CCNC(=O)c1cccn2c(=O)c3cc4ccccc4cc3nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O11 compound treatment 0.266 0.0418 0.6 0.317 0.0977 1.64 1.5823 0.9063 1237773 ChemDiv3_012991 O=C(NCc1ccco1)c2ccc(cc2)n3c(=O)c4ccccc4[nH]c3=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O12 compound treatment 0.231 0.00675 0.1 0.273 0.0537 0.9 0.7061 0.7783 1672781 ChemDiv3_012992 COc1ccc(cc1)n2ncc3c(NCCc4ccccc4)ncnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O13 compound treatment 0.217 -0.00725 -0.1 0.217 -0.00226 -0.04 -0.1001 -0.9069 1392339 ChemDiv3_012993 COC(CNC(=O)c1ccc2c(=O)n(Cc3ccccc3OC)c(=S)[nH]c2c1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O14 compound treatment 0.208 -0.0163 -0.23 0.229 0.00974 0.16 -0.0487 -0.1715 1445000 ChemDiv3_012994 COc1ccc(cc1)n2ncc3c(ncnc23)N(Cc4ccccc4)Cc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O15 compound treatment 0.254 0.0297 0.43 0.259 0.0397 0.67 0.7726 0.9764 1209971 ChemDiv3_012995 Clc1ccc(CSc2nc3cc(ccc3c(=O)n2CC=C)C(=O)NCc4ccco4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O16 compound treatment 0.119 -0.105 -1.51 0.131 -0.0883 -1.48 -2.112 -1.0 1123451 ChemDiv3_012996 CCCNc1ncnc2n(cc(c3ccccc3)c12)c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O17 compound treatment 0.235 0.0107 0.15 0.294 0.0747 1.25 0.9958 0.7879 1375674 ChemDiv3_012997 Cc1ccccc1CSc2nc3ccsc3c(=O)n2Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O18 compound treatment 0.24 0.0158 0.23 0.207 -0.0123 -0.21 0.0138 0.0453 1255048 ChemDiv3_012998 Fc1ccc(cc1)n2cc(c3ccccc3)c4c(NCCC5=CCCCC5)ncnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O19 compound treatment 0.246 0.0217 0.31 0.232 0.0127 0.21 0.3712 0.9833 1325665 ChemDiv3_012999 CCC(C)NC(=O)CSc1nc2ccsc2c(=O)n1c3cccc(Cl)c3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O20 compound treatment 0.232 0.00775 0.11 0.245 0.0257 0.43 0.3839 0.8607 1303433 ChemDiv3_013000 COc1ccc(cc1)n2cc(c3ccccc3)c4c(ncnc24)N5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O21 compound treatment 0.142 -0.0823 -1.18 0.099 -0.12 -2.02 -2.2591 -0.967 3037010 ChemDiv3_013001 OC(=O)C1CCC(Cn2c(SCc3ccccc3Cl)nc4ccsc4c2=O)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O22 compound treatment 0.208 -0.0163 -0.23 0.241 0.0217 0.36 0.0937 0.2165 3120656 ChemDiv3_013002 COc1ccccc1OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)/C=C/c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O23 mock treatment 0.215 -0.00925 -0.13 0.229 0.00974 0.16 0.0221 0.1049 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 O24 mock treatment 0.193 -0.0313 -0.45 0.197 -0.0223 -0.37 -0.5802 -0.996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P01 compound treatment 0.263 0.0388 0.55 0.242 0.0227 0.38 0.6618 0.9834 3120657 ChemDiv3_013003 COc1ccc(cc1)n2nc3CS(=O)(=O)Cc3c2NC(=O)/C=C\c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P02 compound treatment 0.261 0.0367 0.53 0.253 0.0337 0.57 0.7722 0.9993 3037011 ChemDiv3_013004 CCOC(=O)/C=C(\C)/Nc1ccc(CC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P03 compound treatment 0.284 0.0597 0.85 0.259 0.0397 0.67 1.076 0.9925 1525140 ChemDiv3_013005 Cc1cc(NC(=O)CSc2cn(Cc3ccc(F)cc3)c4ccccc24)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P04 compound treatment 0.287 0.0628 0.9 0.299 0.0797 1.34 1.5811 0.9811 3037166 ChemDiv3_013006 CCOC(=O)CCN1N=C(CCC1=O)c2ccc(CC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P05 compound treatment 0.279 0.0548 0.78 0.281 0.0617 1.04 1.2865 0.9905 1474541 ChemDiv3_013007 CCCn1cc(SCC(=O)Nc2sc3CCCc3c2C(=O)OCC)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P06 compound treatment 0.262 0.0377 0.54 0.244 0.0247 0.42 0.6755 0.9916 3037225 ChemDiv3_013008 CCN(CC)S(=O)(=O)c1ccc2n(C)cc(C(=O)O)c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P07 compound treatment 0.254 0.0297 0.43 0.263 0.0437 0.73 0.82 0.9664 3037227 ChemDiv3_013009 O=C(Nc1ccc(cc1)n2nncc2c3ccccc3)c4ccc(cc4)S(=O)(=O)N5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P08 compound treatment 0.224 -2.5E-4 0.0 0.229 0.00974 0.16 0.1131 0.6915 1079745 ChemDiv3_013010 c1ccc(cc1)c2n[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P09 compound treatment 0.248 0.0238 0.34 0.257 0.0377 0.63 0.6881 0.9573 1377188 ChemDiv3_013011 Cc1cccc(NC(=S)N2CCn3cccc3C2c4cccs4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P10 compound treatment 0.259 0.0348 0.5 0.249 0.0297 0.5 0.7044 1.0 3037229 ChemDiv3_013012 COC(=O)c1cc2CS(=O)Cc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P11 compound treatment 0.24 0.0158 0.23 0.262 0.0427 0.72 0.6666 0.8865 3037231 ChemDiv3_013013 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc4[nH]cc(C(=O)O)c(=O)c4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P12 compound treatment 0.244 0.0198 0.28 0.252 0.0327 0.55 0.5883 0.9522 3037232 ChemDiv3_013014 CCOC(=O)C(C)n1nc(C)c2sc3ccccc3c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P13 compound treatment 0.256 0.0318 0.45 0.287 0.0677 1.14 1.1251 0.919 1140560 ChemDiv3_013015 Clc1ccccc1CN2C(=O)C3C4CC(C=C4)C3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P14 compound treatment 0.266 0.0418 0.6 0.234 0.0147 0.25 0.5972 0.9239 1169032 ChemDiv3_013016 COc1cc(cc(OC)c1OC)C(=O)NCCC(=O)N2CCN(C)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P15 compound treatment 0.176 -0.0483 -0.69 0.171 -0.0483 -0.81 -1.0607 -0.9968 3037235 ChemDiv3_013017 Cc1ccc2-c3cc(cn3CCn12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P16 compound treatment 0.253 0.0288 0.41 0.267 0.0477 0.8 0.8574 0.952 1441240 ChemDiv3_013018 Brc1ccc(cc1)S(=O)(=O)NCCC(=O)NC2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P17 compound treatment 0.222 -0.00225 -0.03 0.248 0.0287 0.48 0.3184 0.6585 1709137 ChemDiv3_013019 CC1CCN(CC1)C(=O)c2ccc3C(=O)N(CCC4=CCCCC4)C(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P18 compound treatment 0.28 0.0558 0.8 0.275 0.0557 0.94 1.2254 0.9968 3120838 ChemDiv3_013020 CC1CCCCC1NC(=O)/C(=C/c2ccccc2)/NC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P19 compound treatment 0.257 0.0328 0.47 0.27 0.0507 0.85 0.9335 0.9604 1406386 ChemDiv3_013021 CN(Cc1ccccc1)C(=O)c2c[nH]c3ccc(cc3c2=O)S(=O)(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P20 compound treatment 0.259 0.0348 0.5 0.312 0.0927 1.56 1.4521 0.8887 1686034 ChemDiv3_013022 Fc1ccc(cc1C(=O)Nc2cc(Cl)ccc2Cl)S(=O)(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P21 compound treatment 0.241 0.0168 0.24 0.264 0.0447 0.75 0.7004 0.8886 3037239 ChemDiv3_013023 CCc1ccc2nc(N)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P22 compound treatment 0.235 0.0107 0.15 0.266 0.0467 0.78 0.6635 0.8299 1686507 ChemDiv3_013024 CCCN(CCC)S(=O)(=O)c1ccc(F)c(c1)C(=O)Nc2cc(C)ccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P23 mock treatment 0.22 -0.00425 -0.06 0.219 -2.58E-4 0.0 -0.046 -0.7556 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2037 P24 mock treatment 0.238 0.0138 0.2 0.218 -0.00126 -0.02 0.1241 0.6276 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A01 compound treatment 0.24 0.0252 0.36 0.244 0.0205 0.34 0.4983 0.9997 1352680 ChemDiv3_013025 CCOC(=O)C1CCN(CC1)C(=O)c2ccc(CNS(=O)(=O)c3ccc(C)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A02 compound treatment 0.258 0.0432 0.62 0.223 -4.84E-4 -0.01 0.4311 0.6978 3037241 ChemDiv3_013026 COc1ccccc1CNC(=O)c2ccc3nc4SCCc4cc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A03 compound treatment 0.249 0.0342 0.49 0.23 0.00652 0.11 0.4232 0.8444 1451293 ChemDiv3_013027 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCC2CCC(CC2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A04 compound treatment 0.239 0.0242 0.35 0.263 0.0395 0.66 0.7137 0.954 3037244 ChemDiv3_013028 COc1ccc(Br)cc1/C=C/C(=O)NCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A05 compound treatment 0.247 0.0322 0.46 0.212 -0.0115 -0.19 0.1893 0.3793 1483715 ChemDiv3_013029 Cc1ccc(cc1)S(=O)(=O)N(CCC(=O)O)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A06 compound treatment 0.244 0.0292 0.42 0.223 -4.84E-4 -0.01 0.2895 0.6932 3037246 ChemDiv3_013030 CCC(C)N1Cc2ccccc2N(CC)C1c3ccccc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A07 compound treatment 0.207 -0.00781 -0.11 0.244 0.0205 0.34 0.1645 0.4545 3120839 ChemDiv3_013031 O=S(=O)(Cc1ccccc1)C2=C(CCCCCC2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A08 compound treatment 0.243 0.0282 0.4 0.207 -0.0165 -0.28 0.0895 0.1831 3120840 ChemDiv3_013032 Cc1cc(NC(=O)CSCc2nc(oc2C)c3ccc(C)cc3)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A09 compound treatment 0.234 0.0192 0.27 0.228 0.00452 0.08 0.2477 0.8698 3037285 ChemDiv3_013033 Cc1ccc(CNc2ccc(cc2)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A10 compound treatment 0.248 0.0332 0.47 0.22 -0.00348 -0.06 0.2944 0.6154 3037286 ChemDiv3_013034 Cc1ccc(cc1)S(=O)(=O)N2CCC(=CC2)C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A11 compound treatment 0.226 0.0112 0.16 0.208 -0.0155 -0.26 -0.0705 -0.2311 1035119 ChemDiv3_013035 COc1ccc(CNCC(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A12 compound treatment 0.233 0.0182 0.26 0.201 -0.0225 -0.38 -0.0828 -0.1807 3037288 ChemDiv3_013036 CCOc1ccc(NC(=O)Cn2c3CCCCc3c(cc2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A13 compound treatment 0.213 -0.00181 -0.03 0.203 -0.0205 -0.34 -0.2614 -0.7581 1013700 ChemDiv3_013037 CC(=C1N=C(OC1=O)c2ccccc2)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A14 compound treatment 0.223 0.00819 0.12 0.209 -0.0145 -0.24 -0.089 -0.3299 3037290 ChemDiv3_013038 CCOC(=O)C1CCN(CC1)c2nc3cc(Br)ccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A15 compound treatment 0.213 -0.00181 -0.03 0.223 -4.84E-4 -0.01 -0.024 -0.8866 3037292 ChemDiv3_013039 Cc1ccc(Cn2cc(CCC(=O)O)c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A16 compound treatment 0.217 0.00219 0.03 0.194 -0.0295 -0.49 -0.3277 -0.6609 3037293 ChemDiv3_013040 Cc1ccccc1CSCCC(=O)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A17 compound treatment 0.213 -0.00181 -0.03 0.211 -0.0125 -0.21 -0.1664 -0.7883 3120841 ChemDiv3_013041 Cc1ccc(cc1)C2=NNC(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A18 compound treatment 0.208 -0.00681 -0.1 0.209 -0.0145 -0.24 -0.2407 -0.9193 1680893 ChemDiv3_013042 COC(CNC(=O)c1ccc(CNC(=O)c2cccc(Br)c2)cc1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A19 compound treatment 0.198 -0.0168 -0.24 0.203 -0.0205 -0.34 -0.4131 -0.9847 3037296 ChemDiv3_013043 COC(=O)c1cc2CN(Cc2s1)c3cc(C)cc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A20 compound treatment 0.154 -0.0608 -0.87 0.163 -0.0605 -1.02 -1.3328 -0.997 3120842 ChemDiv3_013044 CCC1Oc2ccc(C)cc2NC1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A21 compound treatment 0.186 -0.0288 -0.41 0.204 -0.0195 -0.33 -0.5226 -0.9934 3037298 ChemDiv3_013045 C(N1CCN(CC1)c2ccccc2)c3cn(Cc4ccccc4)c5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A22 compound treatment 0.218 0.00319 0.05 0.208 -0.0155 -0.26 -0.1515 -0.574 3120843 ChemDiv3_013046 COC(CNC(=O)c1ccc2nc(c3ccccc3)c(nc2c1)c4ccccc4)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A23 mock treatment 0.215 1.94E-4 0.0 0.206 -0.0175 -0.29 -0.2055 -0.7004 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 A24 mock treatment 0.22 0.00519 0.07 0.212 -0.0115 -0.19 -0.0838 -0.4055 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B01 compound treatment 0.246 0.0312 0.45 0.243 0.0195 0.33 0.5471 0.9885 3037299 ChemDiv3_013047 COC(=O)c1cnn2c3CCCCc3c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B02 compound treatment 0.224 0.00919 0.13 0.212 -0.0115 -0.19 -0.0433 -0.1856 3120844 ChemDiv3_013048 Cc1ccccc1CN2C(=O)C3(OCCCO3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B03 compound treatment 0.236 0.0212 0.3 0.258 0.0345 0.58 0.624 0.9544 3120845 ChemDiv3_013049 Cc1cc(C)n2nc(CC(=O)NC3CCCCCCC3)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B04 compound treatment 0.243 0.0282 0.4 0.262 0.0385 0.65 0.7423 0.9742 3037301 ChemDiv3_013050 Cc1ccc(Cn2c(=O)cc(C(=O)NC3CCCCC3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B05 compound treatment 0.252 0.0372 0.53 0.259 0.0355 0.6 0.7977 0.9984 3120846 ChemDiv3_013051 O=C(CNC(=S)N(Cc1cccs1)C2CCCC2)NC3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B06 compound treatment 0.232 0.0172 0.25 0.24 0.0165 0.28 0.3699 0.9982 3120847 ChemDiv3_013052 CCCCN(C)S(=O)(=O)c1ccc2oc(C(=O)O)c(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B07 compound treatment 0.222 0.00719 0.1 0.253 0.0295 0.5 0.4231 0.8361 3037304 ChemDiv3_013053 CC(C)CCNC(=O)C1C2C(=O)N(Cc3ccccc3)CC42OC1(C)C=C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B08 compound treatment 0.224 0.00919 0.13 0.226 0.00252 0.04 0.1228 0.8894 3120848 ChemDiv3_013054 CCC1Oc2ccc(C)cc2N(CC(=O)NC(C)CCc3ccccc3)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B09 compound treatment 0.252 0.0372 0.53 0.267 0.0435 0.73 0.8926 0.9879 3120849 ChemDiv3_013055 COc1cc(Cl)c(C)cc1NC(=S)N(CC2CCC(CC2)C(=O)O)Cc3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B10 compound treatment 0.247 0.0322 0.46 0.22 -0.00348 -0.06 0.2843 0.6124 3037307 ChemDiv3_013056 Cc1ccc(C)c(Cc2c(C)nc3c(cnn3c2C)C(=O)NC4CC4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B11 compound treatment 0.259 0.0442 0.63 0.22 -0.00348 -0.06 0.4056 0.639 3120850 ChemDiv3_013057 CCC(C)NC(=O)c1cc(nc2ccccc12)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B12 compound treatment 0.245 0.0302 0.43 0.227 0.00352 0.06 0.3471 0.7963 3037308 ChemDiv3_013058 OC(=O)c1cccnc1SCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B13 compound treatment 0.242 0.0272 0.39 0.25 0.0265 0.45 0.5897 0.9977 3037345 ChemDiv3_013059 CC(CCc1ccccc1)NC(=O)CSc2nc3nc(C)cc(C)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B14 compound treatment 0.255 0.0402 0.57 0.247 0.0235 0.39 0.6856 0.9832 3037346 ChemDiv3_013060 OC(=O)c1ccccc1C(=O)NCc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B15 compound treatment 0.258 0.0432 0.62 0.255 0.0315 0.53 0.8109 0.997 3037347 ChemDiv3_013061 Cc1ccc(CNC(=O)c2c(C)cc(=O)oc2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B16 compound treatment 0.265 0.0502 0.72 0.208 -0.0155 -0.26 0.3239 0.4242 3037350 ChemDiv3_013062 O=C(NCc1ccccc1)C2CCCN(C2)S(=O)(=O)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B17 compound treatment 0.239 0.0242 0.35 0.249 0.0255 0.43 0.5475 0.9944 3037351 ChemDiv3_013063 O=C(NC1CC1)c2ccc3SCC(=O)N(Cc4ccccc4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B18 compound treatment 0.239 0.0242 0.35 0.216 -0.00748 -0.13 0.1559 0.4234 3037352 ChemDiv3_013064 COc1ccc(NC(=O)c2oc3ccc(cc3c2C)S(=O)(=O)N4CCC5(CC4)OCCO5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B19 compound treatment 0.214 -8.06E-4 -0.01 0.253 0.0295 0.5 0.3421 0.6905 3120851 ChemDiv3_013065 O=C(N1CCCC1)c2ccc3Sc4ccccc4C(=O)N(Cc5ccccc5)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B20 compound treatment 0.208 -0.00681 -0.1 0.25 0.0265 0.45 0.2459 0.5397 1133577 ChemDiv3_013066 COc1ccccc1CNC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B21 compound treatment 0.261 0.0462 0.66 0.284 0.0605 1.02 1.1854 0.9783 3120852 ChemDiv3_013067 O=C1N(CN(CCc2ccccc2)Cc3ccccc3)c4ccccc4C51OCCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B22 compound treatment 0.251 0.0362 0.52 0.273 0.0495 0.83 0.9537 0.9741 3037355 ChemDiv3_013068 O=C(NCCc1ccccc1)C2CCN(CC2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B23 mock treatment 0.238 0.0232 0.33 0.264 0.0405 0.68 0.7154 0.9456 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 B24 mock treatment 0.214 -8.06E-4 -0.01 0.226 0.00252 0.04 0.0217 0.4958 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C01 compound treatment 0.225 0.0102 0.15 0.22 -0.00348 -0.06 0.0618 0.3931 3120853 ChemDiv3_013069 COc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)NC3CCCCC3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C02 compound treatment 0.259 0.0442 0.63 0.222 -0.00148 -0.02 0.4294 0.6787 3120854 ChemDiv3_013070 CCOC(=O)CN1C(=O)/C(=C\c2ccc(OC)c(Br)c2)/Sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C03 compound treatment 0.226 0.0112 0.16 0.212 -0.0115 -0.19 -0.0231 -0.0921 1390430 ChemDiv3_013071 CC(C)C(CC(=O)O)NS(=O)(=O)c1ccc(F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C04 compound treatment 0.214 -8.06E-4 -0.01 0.227 0.00352 0.06 0.0336 0.5583 3120855 ChemDiv3_013072 CCn1cc(C2=NC(CO2)C(C)C)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C05 compound treatment 0.243 0.0282 0.4 0.23 0.00652 0.11 0.3625 0.8675 1368895 ChemDiv3_013073 OC(=O)C1CCC(CNCc2c(Cl)cccc2Cl)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C06 compound treatment 0.057 -0.158 -2.26 0.079 -0.144 -2.43 -3.3108 -0.9994 3120856 ChemDiv3_013074 Cc1cc(C(=O)NCc2ccc(F)cc2)n(n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C07 compound treatment 0.228 0.0132 0.19 0.192 -0.0315 -0.53 -0.2402 -0.4281 3037359 ChemDiv3_013075 OC(=O)CNC(=S)N(Cc1ccccc1)Cc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C08 compound treatment 0.213 -0.00181 -0.03 0.232 0.00852 0.14 0.0828 0.57 3120857 ChemDiv3_013076 CN(C1CCCCC1)S(=O)(=O)c2ccc3ncc(C(=O)Nc4ccc(C)c(F)c4)c(Cl)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C09 compound treatment 0.189 -0.0258 -0.37 0.213 -0.0105 -0.18 -0.3854 -0.9426 1083208 ChemDiv3_013077 COc1cccc(NC(=S)NN)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C10 compound treatment 0.039 -0.176 -2.51 0.257 0.0335 0.56 -1.3804 -0.5357 3120858 ChemDiv3_013078 Cc1ccc(cc1)S(=O)(=O)N2CCC(=CC2)C(=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C11 compound treatment 0.239 0.0242 0.35 0.04 -0.183 -3.08 -1.9329 -0.6237 3037361 ChemDiv3_013079 CC1CCN(CC1)C(=O)c2cc(Cl)nc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C12 compound treatment 0.239 0.0242 0.35 0.198 -0.0255 -0.43 -0.0577 -0.105 3120859 ChemDiv3_013080 CC1CCCCC1NC(=O)c2cc3CSCc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C13 compound treatment 0.229 0.0142 0.2 0.219 -0.00448 -0.08 0.0903 0.4172 3121046 ChemDiv3_013081 CC(=O)N1CCC2(CC1)CC(=O)c3cc(OCC(=O)O)ccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C14 compound treatment 0.04 -0.175 -2.5 0.232 0.00852 0.14 -1.667 -0.6656 1021554 ChemDiv3_013082 NNC(=O)c1cc2ccccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C15 compound treatment 0.229 0.0142 0.2 0.253 0.0295 0.5 0.4939 0.9224 3037364 ChemDiv3_013083 Cc1ccc(Sc2ccc(cc2NC=O)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C16 compound treatment 0.222 0.00719 0.1 0.047 -0.176 -2.96 -2.0218 -0.6821 1543012 ChemDiv3_013084 Cc1cc(C)c(NC(=O)c2cc(ccc2F)S(=O)(=O)N3CCc4ccccc34)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C17 compound treatment 0.244 0.0292 0.42 0.107 -0.116 -1.96 -1.0872 -0.5438 3037402 ChemDiv3_013085 CCCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(Cl)cc2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C18 compound treatment 0.042 -0.173 -2.47 0.226 0.00252 0.04 -1.7179 -0.6949 1445682 ChemDiv3_013086 CCC(C)NC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N(C)c3cc(C)ccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C19 compound treatment 0.226 0.0112 0.16 0.243 0.0195 0.33 0.3448 0.9458 3037404 ChemDiv3_013087 Cc1ccc(/C=C\2/Sc3ccccc3NC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C20 compound treatment 0.246 0.0312 0.45 0.194 -0.0295 -0.49 -0.0344 -0.0517 3037406 ChemDiv3_013088 c1ccc2sc3c(sc4ccccc4[nH]c3nc2c1)c5ccncc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C21 compound treatment 0.218 0.00319 0.05 0.194 -0.0295 -0.49 -0.3176 -0.6391 3037407 ChemDiv3_013089 CCC1=Nc2cc(ccc2Sc3ccc(Cl)cc13)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C22 compound treatment 0.171 -0.0438 -0.63 0.207 -0.0165 -0.28 -0.6387 -0.9325 1280017 ChemDiv3_013090 O=C(CSc1nnc(c2ccccc2)c(n1)c3ccccc3)NCCC4=CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C23 mock treatment 0.06 -0.155 -2.21 0.041 -0.182 -3.06 -3.7315 -0.9873 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 C24 mock treatment 0.202 -0.0128 -0.18 0.213 -0.0105 -0.18 -0.254 -0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D01 compound treatment 0.251 0.0362 0.52 0.204 -0.0195 -0.33 0.1348 0.2202 3037409 ChemDiv3_013091 Cc1ccc(cc1)N2C(=O)CC2(C(=O)NC3CCCCC3)c4ccccc4F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D02 compound treatment 0.224 0.00919 0.13 0.233 0.00952 0.16 0.2059 0.9953 3121047 ChemDiv3_013092 Cc1cc(C)n2nc(SCCC(=O)NCc3c(F)cc(F)cc3F)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D03 compound treatment 0.295 0.0802 1.15 0.27 0.0465 0.78 1.3632 0.9824 3037411 ChemDiv3_013093 Cc1cc(C)n2nc(CC(=O)NCc3ccccc3Cl)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D04 compound treatment 0.276 0.0612 0.88 0.261 0.0375 0.63 1.0642 0.9869 3121048 ChemDiv3_013094 Cc1nc2c(cnn2c(O)c1Cc3ccccc3Cl)C(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D05 compound treatment 0.299 0.0842 1.2 0.305 0.0815 1.37 1.819 0.998 3121049 ChemDiv3_013095 O=C(CNC(=S)N(Cc1ccccc1)Cc2cccnc2)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D06 compound treatment 0.222 0.00719 0.1 0.207 -0.0165 -0.28 -0.1229 -0.4163 3037414 ChemDiv3_013096 CC(NC(=O)c1cnn2c(cc(nc12)c3cccs3)C(F)(F)F)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D07 compound treatment 0.177 -0.0378 -0.54 0.184 -0.0395 -0.66 -0.851 -0.9949 3121050 ChemDiv3_013097 Fc1ccc(CN(C2CCCCC2)C(=S)Nc3ccccc3F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D08 compound treatment 0.304 0.0892 1.28 0.279 0.0555 0.93 1.561 0.9881 3121051 ChemDiv3_013098 CC1CCN(CC1)S(=O)(=O)c2ccc3[nH]c(=O)cc(C(=O)NCCCN4CCOCC4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D09 compound treatment 0.203 -0.0118 -0.17 0.187 -0.0365 -0.61 -0.5524 -0.8697 1382114 ChemDiv3_013099 COc1ccc(cc1)c2cc(C(=O)NC3CCCC3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D10 compound treatment 0.274 0.0592 0.85 0.291 0.0675 1.13 1.4 0.9897 3121052 ChemDiv3_013100 CC(C)NC(=O)c1cnn2c(C)c(Cc3c(F)cccc3Cl)c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D11 compound treatment 0.282 0.0672 0.96 0.276 0.0525 0.88 1.3029 0.9991 3037417 ChemDiv3_013101 O=C(NCCC1=CCCCC1)c2cc(nc3ccccc23)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D12 compound treatment 0.246 0.0312 0.45 0.311 0.0875 1.47 1.3541 0.8821 3121053 ChemDiv3_013102 CCC(Sc1ncccc1C(=O)O)C(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D13 compound treatment 0.266 0.0512 0.73 0.26 0.0365 0.61 0.9512 0.9961 3037419 ChemDiv3_013103 Cc1cc(C)n2nc(SCC(=O)NCc3ccc(Cl)cc3)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D14 compound treatment 0.285 0.0702 1.0 0.284 0.0605 1.02 1.4282 1.0 3121054 ChemDiv3_013104 CC(CCc1ccccc1)NC(=O)c2ccccc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D15 compound treatment 0.276 0.0612 0.88 0.212 -0.0115 -0.19 0.4826 0.5385 3121055 ChemDiv3_013105 COc1ccc(CCNC(=O)c2c(C)cc(=O)oc2C)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D16 compound treatment 0.236 0.0212 0.3 0.219 -0.00448 -0.08 0.1611 0.5159 3037422 ChemDiv3_013106 Cc1ccc(cc1C)c2cc(C(=O)N3CCCCC3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D17 compound treatment 0.242 0.0272 0.39 0.27 0.0465 0.78 0.8271 0.9482 3121056 ChemDiv3_013107 CN(C)CCNC(=O)c1ccc2SCC(=O)N(Cc3ccccc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D18 compound treatment 0.257 0.0422 0.6 0.287 0.0635 1.07 1.1806 0.9637 3121057 ChemDiv3_013108 CC(CCc1ccccc1)NC(=O)C2CCN(CC2)S(=O)(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D19 compound treatment 0.241 0.0262 0.37 0.211 -0.0125 -0.21 0.1168 0.272 3037424 ChemDiv3_013109 O=C(NC1CC1)c2ccc3Sc4ccccc4C(=O)N(Cc5ccccc5)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D20 compound treatment 0.254 0.0392 0.56 0.24 0.0165 0.28 0.5924 0.9473 1240208 ChemDiv3_013110 Cc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D21 compound treatment 0.247 0.0322 0.46 0.267 0.0435 0.73 0.8421 0.9753 3037460 ChemDiv3_013111 CC(C)N(C)C1CCN(CC1)C(=O)Nc2ccc(C)c(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D22 compound treatment 0.241 0.0262 0.37 0.244 0.0205 0.34 0.5084 0.9991 3037462 ChemDiv3_013112 O=C(NC1CCCC1)C2CCN(CC2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D23 mock treatment 0.233 0.0182 0.26 0.222 -0.00148 -0.02 0.1664 0.6365 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 D24 mock treatment 0.21 -0.00481 -0.07 0.228 0.00452 0.08 0.005 0.0487 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E01 compound treatment 0.248 0.0332 0.47 0.212 -0.0115 -0.19 0.1994 0.3892 1435675 ChemDiv3_013113 CCOC(=O)c1ccc(CNCc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E02 compound treatment 0.267 0.0522 0.75 0.239 0.0155 0.26 0.712 0.9005 3037464 ChemDiv3_013114 O=C/1Nc2ccccc2O\C1=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E03 compound treatment 0.25 0.0352 0.5 0.228 0.00452 0.08 0.4096 0.8045 1503635 ChemDiv3_013115 COc1ccc(cc1)S(=O)(=O)NC(CC(=O)O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E04 compound treatment 0.188 -0.0268 -0.38 0.237 0.0135 0.23 -0.1107 -0.2485 3037466 ChemDiv3_013116 CCn1cc(C2=NC(CO2)c3ccccc3)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E05 compound treatment 0.241 0.0262 0.37 0.272 0.0485 0.81 0.8407 0.9379 3037467 ChemDiv3_013117 OC(=O)CNCc1c(Cl)cccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E06 compound treatment 0.317 0.102 1.46 0.279 0.0555 0.93 1.6925 0.9764 3037469 ChemDiv3_013118 Cc1nccc2[nH]c(=O)c(cc12)C(=O)NCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E07 compound treatment 0.297 0.0822 1.18 0.267 0.0435 0.73 1.3478 0.9738 3121058 ChemDiv3_013119 CCOC(=O)C1CCC(CNCc2ccc(Cl)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E08 compound treatment 0.274 0.0592 0.85 0.224 5.16E-4 0.01 0.6048 0.7143 3121059 ChemDiv3_013120 COc1ccc(CNC(=O)c2cc3CN(Cc4ccccc4)Cc3s2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E09 compound treatment 0.246 0.0312 0.45 0.249 0.0255 0.43 0.6183 0.9998 3037472 ChemDiv3_013121 CCc1ccc(NC(=S)NN)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E10 compound treatment 0.271 0.0562 0.8 0.295 0.0715 1.2 1.4171 0.981 3121060 ChemDiv3_013122 Brc1ccc(cc1)C(=O)CN2C(=O)C3(OCCO3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E11 compound treatment 0.309 0.0942 1.35 0.247 0.0235 0.39 1.2318 0.8774 3037474 ChemDiv3_013123 CCOC(=O)c1oc2ccc(cc2c1C)S(=O)(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E12 compound treatment 0.299 0.0842 1.2 0.252 0.0285 0.48 1.19 0.9183 3121061 ChemDiv3_013124 Clc1ncccc1NC(=O)C2CSC(=N2)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E13 compound treatment 0.272 0.0572 0.82 0.253 0.0295 0.5 0.9288 0.9711 3037476 ChemDiv3_013125 COC(=O)c1cc(nc2ccccc12)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E14 compound treatment 0.234 0.0192 0.27 0.225 0.00152 0.03 0.2121 0.7694 1263724 ChemDiv3_013126 CCOc1ccccc1N(C)C(=O)c2cc(ccc2F)S(=O)(=O)N(CC)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E15 compound treatment 0.298 0.0832 1.19 0.299 0.0755 1.27 1.7377 0.9995 3037477 ChemDiv3_013127 CCOC(=O)COc1ccc2OC(C)(C)CC(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E16 compound treatment 0.25 0.0352 0.5 0.279 0.0555 0.93 1.0148 0.9582 1129134 ChemDiv3_013128 Cc1ccccc1CSCC(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E17 compound treatment 0.228 0.0132 0.19 0.248 0.0245 0.41 0.4244 0.9375 3037480 ChemDiv3_013129 CCOC(=O)Cn1nc(ccc1=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E18 compound treatment 0.273 0.0582 0.83 0.225 0.00152 0.03 0.6066 0.7284 1343782 ChemDiv3_013130 CC(C)CCNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N(C)c3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E19 compound treatment 0.265 0.0502 0.72 0.243 0.0195 0.33 0.7393 0.9368 3037482 ChemDiv3_013131 Clc1cccc(/C=C/2\Sc3ccccc3NC2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E20 compound treatment 0.26 0.0452 0.65 0.222 -0.00148 -0.02 0.4395 0.6794 3121062 ChemDiv3_013132 CCOC(=O)c1sc2ccc(cc2c1N)S(=O)(=O)N3CC(C)CC(C)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E21 compound treatment 0.168 -0.0468 -0.67 0.17 -0.0535 -0.9 -1.1082 -0.9896 3121063 ChemDiv3_013133 Cc1c(Cl)cccc1NC(=S)NCC(c2c[nH]c3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E22 compound treatment 0.242 0.0272 0.39 0.246 0.0225 0.38 0.5423 0.9999 3037484 ChemDiv3_013134 COc1ccccc1N2CCN(CC2)C(=O)c3cnn4c(C)c(Cc5cccc(C)c5)c(C)nc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E23 mock treatment 0.214 -8.06E-4 -0.01 0.232 0.00852 0.14 0.0929 0.6479 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 E24 mock treatment 0.203 -0.0118 -0.17 0.224 5.16E-4 0.01 -0.1133 -0.67 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F01 compound treatment 0.25 0.0352 0.5 0.232 0.00852 0.14 0.457 0.8734 3121064 ChemDiv3_013135 Cc1ccc(cc1)N2C(=O)CC2(C(=O)NC3CCCCC3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F02 compound treatment 0.247 0.0322 0.46 0.271 0.0475 0.8 0.8895 0.9659 3037485 ChemDiv3_013136 CC(Sc1nc2nc(C)cc(C)n2n1)C(=O)NC3CCCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F03 compound treatment 0.261 0.0462 0.66 0.24 0.0165 0.28 0.6632 0.9256 3121065 ChemDiv3_013137 CCOC(=O)N1CCN(CC1)C(=O)CNC(=S)N(Cc2cccs2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F04 compound treatment 0.28 0.0652 0.93 0.278 0.0545 0.91 1.3064 1.0 3121066 ChemDiv3_013138 Fc1cc(F)c(CNC(=O)c2ccc3SCC(=O)Nc3c2)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F05 compound treatment 0.255 0.0402 0.57 0.244 0.0205 0.34 0.65 0.97 3037533 ChemDiv3_013139 CC(C)CCNC(=O)c1cnn2c(O)c(Cl)c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F06 compound treatment 0.311 0.0962 1.38 0.311 0.0875 1.47 2.0116 0.9995 3037534 ChemDiv3_013140 FC(F)(F)c1cc(nc2c(cnn12)C(=O)N3CCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F07 compound treatment 0.334 0.119 1.7 0.321 0.0975 1.64 2.3629 0.9998 3037536 ChemDiv3_013141 CC1(OC23CN(Cc4ccccc4)C(=O)C3C1C(=O)NCc5ccco5)C=C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F08 compound treatment 0.296 0.0812 1.16 0.23 0.00652 0.11 0.8985 0.7703 3037537 ChemDiv3_013142 CCOc1ccc(cc1)c2cc(C(=O)NCC3COc4ccccc4O3)c5ccccc5n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F09 compound treatment 0.301 0.0862 1.23 0.293 0.0695 1.17 1.6968 0.9996 3037538 ChemDiv3_013143 COc1ccc(cc1)c2cc(C(=O)NC3CCCCC3C)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F10 compound treatment 0.313 0.0982 1.4 0.316 0.0925 1.55 2.0911 0.9987 3037540 ChemDiv3_013144 Cc1c(oc2ccc(cc12)S(=O)(=O)NCc3ccc(C)cc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F11 compound treatment 0.273 0.0582 0.83 0.284 0.0605 1.02 1.3068 0.9951 3121067 ChemDiv3_013145 CC(C)CCNC(=O)c1cc(nc2ccccc12)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F12 compound treatment 0.311 0.0962 1.38 0.314 0.0905 1.52 2.0472 0.9988 3121068 ChemDiv3_013146 CCN(CC)S(=O)(=O)N1CCCC(C1)C(=O)NCc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F13 compound treatment 0.251 0.0362 0.52 0.283 0.0595 1.0 1.0724 0.9532 3037542 ChemDiv3_013147 CCOC(=O)c1ccc(N2CCN(CC2)c3ccccc3F)c(NC(=O)Nc4ccc(CC)cc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F14 compound treatment 0.279 0.0642 0.92 0.265 0.0415 0.7 1.142 0.9907 3121255 ChemDiv3_013148 Cc1ccc(CNC(=O)c2ccccc2C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F15 compound treatment 0.296 0.0812 1.16 0.305 0.0815 1.37 1.7887 0.9967 3121256 ChemDiv3_013149 CN(CCNC(=O)c1c(C)cc(=O)oc1C)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F16 compound treatment 0.17 -0.0448 -0.64 0.18 -0.0435 -0.73 -0.9693 -0.9979 3037545 ChemDiv3_013150 Cc1c(oc2ccc(cc12)S(=O)(=O)N3CCCC3)C(=O)Nc4ccccc4Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F17 compound treatment 0.277 0.0622 0.89 0.265 0.0415 0.7 1.1218 0.9927 3121257 ChemDiv3_013151 C=CCNC(=O)c1ccc2SCC(=O)N(Cc3ccccc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F18 compound treatment 0.306 0.0912 1.3 0.294 0.0705 1.18 1.7592 0.9988 3121258 ChemDiv3_013152 CC1CCCN(C1)S(=O)(=O)c2ccc3[nH]c(=O)cc(C(=O)NCCCN4CCCCC4C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F19 compound treatment 0.296 0.0812 1.16 0.236 0.0125 0.21 0.9698 0.8217 3037547 ChemDiv3_013153 O=C(NCc1cccs1)c2ccc3Sc4ccccc4C(=O)N(Cc5ccccc5)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F20 compound treatment 0.293 0.0782 1.12 0.269 0.0455 0.76 1.3311 0.9827 3121259 ChemDiv3_013154 CN(C1CCCCC1)S(=O)(=O)c2ccc3oc(C(=O)Nc4ccc(C)c(C)c4)c(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F21 compound treatment 0.283 0.0682 0.98 0.299 0.0755 1.27 1.586 0.9916 3037548 ChemDiv3_013155 CCc1ccc(NC(=O)N2CCC(CC2)N(C)C(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F22 compound treatment 0.288 0.0732 1.05 0.24 0.0165 0.28 0.9363 0.8645 3121260 ChemDiv3_013156 CC(C)CCNC(=O)C1CCN(CC1)S(=O)(=O)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F23 mock treatment 0.257 0.0422 0.6 0.242 0.0185 0.31 0.6465 0.9524 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 F24 mock treatment 0.199 -0.0158 -0.23 0.232 0.00852 0.14 -0.0588 -0.2198 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G01 compound treatment 0.246 0.0312 0.45 0.232 0.00852 0.14 0.4166 0.8891 1461588 ChemDiv3_013157 Cc1cccc(c1)n2cnc3cc(ccc23)C(=O)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G02 compound treatment 0.235 0.0202 0.29 0.281 0.0575 0.97 0.8868 0.8801 3121261 ChemDiv3_013158 COc1ccc(/C=C/C(=O)NCCCN2CCCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G03 compound treatment 0.228 0.0132 0.19 0.283 0.0595 1.0 0.8398 0.8261 1394364 ChemDiv3_013159 Cc1nc2cc(ccc2n1c3cccc(C)c3)C(=O)NCCN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G04 compound treatment 0.223 0.00819 0.12 0.231 0.00752 0.13 0.1721 0.9993 3037552 ChemDiv3_013160 COC(=O)c1ccc2S/C(=C\c3ccccc3OC)/C(=O)N(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G05 compound treatment 0.298 0.0832 1.19 0.232 0.00852 0.14 0.9425 0.7864 3121262 ChemDiv3_013161 OC(=O)CCNCc1c(Cl)cccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G06 compound treatment 0.241 0.0262 0.37 0.213 -0.0105 -0.18 0.1405 0.3394 3037554 ChemDiv3_013162 Cc1ccc(CSCC2COC(=N2)c3cccs3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G07 compound treatment 0.332 0.117 1.68 0.315 0.0915 1.54 2.2714 0.999 3121263 ChemDiv3_013163 CCOC(=O)c1ccc(CN(Cc2ccccc2C)S(=O)(=O)c3ccc4OCCOc4c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G08 compound treatment 0.296 0.0812 1.16 0.268 0.0445 0.75 1.3495 0.9772 3121264 ChemDiv3_013164 COc1cccc(NC(=S)N2CCC3(CC2)CC(=O)c4ccccc4O3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G09 compound treatment 0.241 0.0262 0.37 0.229 0.00552 0.09 0.3304 0.8561 1463646 ChemDiv3_013165 Cc1cccc(NC(=S)NN)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G10 compound treatment 0.198 -0.0168 -0.24 0.304 0.0805 1.35 0.7856 0.5723 3037556 ChemDiv3_013166 O=C(Cn1c2CCCCc2c(cc1=O)c3ccccc3)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G11 compound treatment 0.282 0.0672 0.96 0.263 0.0395 0.66 1.1486 0.9836 3121265 ChemDiv3_013167 CCOC(=O)CN1C(=O)C2(OCCCO2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G12 compound treatment 0.229 0.0142 0.2 0.289 0.0655 1.1 0.9211 0.8237 3121266 ChemDiv3_013168 CC1N(Cc2ccccc2)C(=O)C(CC(=O)Nc3c(C)cccc3C)n4c1nc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G13 compound treatment 0.223 0.00819 0.12 0.272 0.0485 0.81 0.6587 0.8006 3037613 ChemDiv3_013169 COC(=O)c1ccc(N2CCC(C)CC2)c(N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G14 compound treatment 0.242 0.0272 0.39 0.228 0.00452 0.08 0.3286 0.8293 1190011 ChemDiv3_013170 CCc1ccc(cc1)N(C)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCCCCC4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G15 compound treatment 0.164 -0.0508 -0.73 0.134 -0.0895 -1.5 -1.5759 -0.9445 3037614 ChemDiv3_013171 CN(C(=O)/C=C/C(=O)O)c1cccc(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G16 compound treatment 0.245 0.0302 0.43 0.235 0.0115 0.19 0.4421 0.9343 3037616 ChemDiv3_013172 Clc1ccccc1CSCCC(=O)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G17 compound treatment 0.277 0.0622 0.89 0.28 0.0565 0.95 1.2998 0.9995 3037617 ChemDiv3_013173 Clc1ccccc1Cn2cccc2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G18 compound treatment 0.271 0.0562 0.8 0.278 0.0545 0.91 1.2154 0.9979 1592294 ChemDiv3_013174 Brc1ccc(cc1)S(=O)(=O)NC(Cc2ccccc2)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G19 compound treatment 0.268 0.0532 0.76 0.257 0.0335 0.56 0.9358 0.989 3037619 ChemDiv3_013175 COc1ccc(/C=C/2\Sc3ccccc3NC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G20 compound treatment 0.272 0.0572 0.82 0.263 0.0395 0.66 1.0474 0.9946 1161949 ChemDiv3_013176 CCOC(=O)c1sc2ccc(cc2c1N)S(=O)(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G21 compound treatment 0.303 0.0882 1.26 0.273 0.0495 0.83 1.4797 0.9795 3037622 ChemDiv3_013177 CCn1cc(CN(Cc2ccccc2)C(=S)Nc3ccc(Cl)cc3OC)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G22 compound treatment 0.157 -0.0578 -0.83 0.124 -0.0995 -1.67 -1.7654 -0.9475 3121267 ChemDiv3_013178 CC1CN(CCN1c2ccc(C)cc2)C(=O)c3cnn4c(C)c(Cc5ccccc5Cl)c(C)nc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G23 mock treatment 0.19 -0.0248 -0.35 0.196 -0.0275 -0.46 -0.5771 -0.9916 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 G24 mock treatment 0.193 -0.0218 -0.31 0.22 -0.00348 -0.06 -0.2619 -0.8253 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H01 compound treatment 0.245 0.0302 0.43 0.22 -0.00348 -0.06 0.264 0.6058 3121268 ChemDiv3_013179 CC1CCCC(NC(=O)CNC(=S)N(Cc2cccs2)Cc3ccccc3)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H02 compound treatment 0.248 0.0332 0.47 0.234 0.0105 0.18 0.4605 0.9092 3037624 ChemDiv3_013180 CC(Sc1nc2nc(C)cc(C)n2n1)C(=O)NCc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H03 compound treatment 0.285 0.0702 1.0 0.215 -0.00848 -0.14 0.6093 0.6008 3121269 ChemDiv3_013181 CC1CCCC(NC(=O)c2cnn3c(C)c4CCCCc4nc23)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H04 compound treatment 0.257 0.0422 0.6 0.239 0.0155 0.26 0.6109 0.9294 3037626 ChemDiv3_013182 O=C(NCC1COc2ccccc2O1)c3ccc4SCC(=O)Nc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H05 compound treatment 0.322 0.107 1.53 0.258 0.0345 0.58 1.4938 0.9114 3121270 ChemDiv3_013183 Cc1nc2c(cnn2c(O)c1Cl)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H06 compound treatment 0.261 0.0462 0.66 0.297 0.0735 1.23 1.3397 0.9572 3121271 ChemDiv3_013184 CCC(C)NC(=O)c1cnn2c(cc(nc12)c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H07 compound treatment 0.261 0.0462 0.66 0.278 0.0545 0.91 1.1142 0.9872 3037629 ChemDiv3_013185 O=C(NCc1ccccc1)C2C3OC4(CN(Cc5cccnc5)C(=O)C24)C=C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H08 compound treatment 0.331 0.116 1.66 0.292 0.0685 1.15 1.9884 0.9838 3121272 ChemDiv3_013186 CCOc1ccc(cc1)c2cc(C(=O)NCCCN3CCCCC3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H09 compound treatment 0.302 0.0872 1.25 0.261 0.0375 0.63 1.3271 0.9499 1381923 ChemDiv3_013187 COc1ccc(cc1)c2cc(C(=O)NCCc3ccccc3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H10 compound treatment 0.241 0.0262 0.37 0.315 0.0915 1.54 1.351 0.8545 3037631 ChemDiv3_013188 Cc1c(oc2ccc(cc12)S(=O)(=O)NCCc3ccccc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H11 compound treatment 0.304 0.0892 1.28 0.272 0.0485 0.81 1.4779 0.9765 3121273 ChemDiv3_013189 COc1cc(CN(C2CCCC2)C(=S)NCC(=O)N3CCCC3)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H12 compound treatment 0.328 0.113 1.62 0.303 0.0795 1.33 2.0886 0.9954 3037633 ChemDiv3_013190 Cc1ccc(CNC(=O)c2cccnc2SCC=C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H13 compound treatment 0.152 -0.0628 -0.9 0.156 -0.0675 -1.13 -1.4361 -0.9934 3121274 ChemDiv3_013191 COC(=O)c1cnn2c(NC3CCCCC3)c([nH]c12)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H14 compound treatment 0.351 0.136 1.95 0.305 0.0815 1.37 2.3449 0.9851 3121275 ChemDiv3_013192 CC(NC(=O)c1ccccc1C(=O)O)C2(CC3CC4CC(C3)C2)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H15 compound treatment 0.211 -0.00381 -0.05 0.28 0.0565 0.95 0.6322 0.6654 3037636 ChemDiv3_013193 Cc1ccc(CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)NCCN5CCOCC5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H16 compound treatment 0.201 -0.0138 -0.2 0.18 -0.0435 -0.73 -0.6557 -0.8673 3121276 ChemDiv3_013194 Cc1c(oc2ccc(cc12)S(=O)(=O)N3CCCC3)C(=O)Nc4ccc(C)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H17 compound treatment 0.294 0.0792 1.13 0.238 0.0145 0.24 0.9733 0.84 3037696 ChemDiv3_013195 O=C(NCc1cccs1)c2ccc3SCC(=O)N(Cc4ccccc4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H18 compound treatment 0.281 0.0662 0.95 0.28 0.0565 0.95 1.3402 1.0 3037698 ChemDiv3_013196 CC(CCc1ccccc1)NC(=O)c2cc(=O)[nH]c3ccc(cc23)S(=O)(=O)N4CCCC(C)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H19 compound treatment 0.272 0.0572 0.82 0.24 0.0165 0.28 0.7745 0.8966 3037699 ChemDiv3_013197 CCCNC(=O)c1ccc2Sc3ccccc3C(=O)N(Cc4ccccc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H20 compound treatment 0.253 0.0382 0.55 0.237 0.0135 0.23 0.5467 0.9242 3037700 ChemDiv3_013198 CC(C)CCNC(=O)c1sc2ccc(cc2c1N)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H21 compound treatment 0.24 0.0252 0.36 0.257 0.0335 0.56 0.6526 0.9768 3037702 ChemDiv3_013199 O=C(CN1C(=O)C2(OCCCO2)c3ccccc13)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H22 compound treatment 0.253 0.0382 0.55 0.247 0.0235 0.39 0.6654 0.9873 3037704 ChemDiv3_013200 CCOc1ccc(CNC(=O)c2cc(=O)[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H23 mock treatment 0.251 0.0362 0.52 0.224 5.16E-4 0.01 0.3722 0.7188 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 H24 mock treatment 0.206 -0.00881 -0.13 0.206 -0.0175 -0.29 -0.2966 -0.9287 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I01 compound treatment 0.27 0.0552 0.79 0.236 0.0125 0.21 0.7068 0.8652 1456749 ChemDiv3_013201 Cc1cccc(c1)n2cnc3cc(ccc23)C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I02 compound treatment 0.242 0.0272 0.39 0.224 5.16E-4 0.01 0.2812 0.7227 3037706 ChemDiv3_013202 COC(=O)/C=C/c1ccc(SC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I03 compound treatment 0.187 -0.0278 -0.4 0.158 -0.0655 -1.1 -1.0584 -0.9055 1701477 ChemDiv3_013203 Cc1nc2cc(ccc2n1c3cccc(C)c3)C(=O)NCc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I04 compound treatment 0.274 0.0592 0.85 0.279 0.0555 0.93 1.2576 0.9989 3037708 ChemDiv3_013204 COc1cccc(NC(=O)Cn2c(C)cc(C)c(C#N)c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I05 compound treatment 0.301 0.0862 1.23 0.272 0.0485 0.81 1.4476 0.9797 1437371 ChemDiv3_013205 CCOC(=O)C1CCC(CN(Cc2ccccc2)S(=O)(=O)c3ccc(F)c(C)c3)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I06 compound treatment 0.182 -0.0328 -0.47 0.158 -0.0655 -1.1 -1.109 -0.928 3121452 ChemDiv3_013206 CN1C(=O)/C(=C/c2ccccc2Cl)/Sc3ccc(cc13)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I07 compound treatment 0.278 0.0632 0.9 0.298 0.0745 1.25 1.5235 0.9873 3037711 ChemDiv3_013207 OC(=O)c1ccc(CNCc2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I08 compound treatment 0.05 -0.165 -2.36 0.057 -0.166 -2.79 -3.6427 -0.9964 3121453 ChemDiv3_013208 Clc1cccc(NC(=S)NC2CCSc3ccc(Cl)cc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I09 compound treatment 0.297 0.0822 1.18 0.259 0.0355 0.6 1.2528 0.9504 3037712 ChemDiv3_013209 CCc1ccc(cc1)N2C(=O)CN(Cc3ccccc3)C2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I10 compound treatment 0.255 0.0402 0.57 0.26 0.0365 0.61 0.8399 0.9995 3121454 ChemDiv3_013210 CCOc1ccc(/N=C/c2c([nH]c3ccccc23)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I11 compound treatment 0.295 0.0802 1.15 0.29 0.0665 1.12 1.6005 0.9999 3037714 ChemDiv3_013211 COc1ccc(cc1)C2OCC(CO)(CO)CO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I12 compound treatment 0.305 0.0902 1.29 0.295 0.0715 1.2 1.761 0.9994 3121455 ChemDiv3_013212 COc1ccc(cc1)C2OC(=O)CC2C(=O)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I13 compound treatment 0.233 0.0182 0.26 0.207 -0.0165 -0.28 -0.0116 -0.0306 3037715 ChemDiv3_013213 COC(=O)c1cnn2c(O)c(Cc3ccc(F)cc3Cl)c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I14 compound treatment 0.27 0.0552 0.79 0.243 0.0195 0.33 0.7899 0.9241 1632180 ChemDiv3_013214 CCc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I15 compound treatment 0.123 -0.0918 -1.31 0.143 -0.0805 -1.35 -1.8837 -0.9999 3037717 ChemDiv3_013215 CCC1Sc2ccccc2NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I16 compound treatment 0.312 0.0972 1.39 0.187 -0.0365 -0.61 0.55 0.3621 3121456 ChemDiv3_013216 Clc1ccccc1CNC(=O)CCSCc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I17 compound treatment 0.11 -0.105 -1.5 0.102 -0.121 -2.04 -2.5018 -0.9886 3037719 ChemDiv3_013217 Clc1ccc(CN2C(=O)CSc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I18 compound treatment 0.293 0.0782 1.12 0.276 0.0525 0.88 1.4141 0.993 1482900 ChemDiv3_013218 Brc1ccc(cc1)S(=O)(=O)NC(CC(=O)NC2CC2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I19 compound treatment 0.256 0.0412 0.59 0.212 -0.0115 -0.19 0.2803 0.4522 3121457 ChemDiv3_013219 CCc1ccc(/C=C/2\Sc3ccccc3N(CC(=O)O)C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I20 compound treatment 0.254 0.0392 0.56 0.246 0.0225 0.38 0.6636 0.9816 3037722 ChemDiv3_013220 COC(=O)c1ccc(Sc2ccc(Cl)cc2)c(N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I21 compound treatment 0.181 -0.0338 -0.48 0.183 -0.0405 -0.68 -0.8224 -0.9861 3121458 ChemDiv3_013221 COc1ccc(NC(=S)NCC(c2c[nH]c3ccccc23)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I22 compound treatment 0.2 -0.0148 -0.21 0.225 0.00152 0.03 -0.1318 -0.6177 3037723 ChemDiv3_013222 COC(=O)c1cnn2c(C)c(Cc3ccccc3)c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I23 mock treatment 0.191 -0.0238 -0.34 0.217 -0.00648 -0.11 -0.3177 -0.8888 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 I24 mock treatment 0.21 -0.00481 -0.07 0.196 -0.0275 -0.46 -0.3748 -0.8036 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J01 compound treatment 0.233 0.0182 0.26 0.233 0.00952 0.16 0.297 0.9725 3037776 ChemDiv3_013223 O=C(CNC(=S)N(Cc1cccs1)Cc2ccccc2)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J02 compound treatment 0.308 0.0932 1.33 0.249 0.0255 0.43 1.2454 0.8895 3037778 ChemDiv3_013224 Clc1ccc(Cn2c(=O)cc(C(=O)NCc3cccs3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J03 compound treatment 0.264 0.0492 0.7 0.254 0.0305 0.51 0.8597 0.9878 3037779 ChemDiv3_013225 CC(C)CCNC(=O)c1cnn2c(cc(nc12)c3ccco3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J04 compound treatment 0.297 0.0822 1.18 0.215 -0.00848 -0.14 0.7306 0.617 3037780 ChemDiv3_013226 FC(F)(F)c1cccc(c1)N2CCN(CC2)C(=O)c3ccc4SCC(=O)Nc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J05 compound treatment 0.264 0.0492 0.7 0.253 0.0295 0.5 0.8479 0.9853 3037782 ChemDiv3_013227 Cc1nc2c(cnn2c(O)c1Cl)C(=O)NCCc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J06 compound treatment 0.262 0.0472 0.68 0.287 0.0635 1.07 1.2311 0.9757 3037784 ChemDiv3_013228 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCCN3CCCCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J07 compound treatment 0.317 0.102 1.46 0.223 -4.84E-4 -0.01 1.0279 0.7032 1463194 ChemDiv3_013229 O=C(NC1CCCCC1)c2cc(nc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J08 compound treatment 0.301 0.0862 1.23 0.289 0.0655 1.1 1.6493 0.9984 3121459 ChemDiv3_013230 Cc1nc2c(cnn2c(C)c1Cc3ccccc3Cl)C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J09 compound treatment 0.25 0.0352 0.5 0.273 0.0495 0.83 0.9436 0.9712 3037787 ChemDiv3_013231 COc1ccc(cc1)c2cc(C(=O)NCc3cccc(OC)c3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J10 compound treatment 0.304 0.0892 1.28 0.249 0.0255 0.43 1.205 0.8954 3121460 ChemDiv3_013232 CC(C)CCNS(=O)(=O)c1ccc2oc(C(=O)O)c(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J11 compound treatment 0.261 0.0462 0.66 0.238 0.0145 0.24 0.6395 0.9081 3037790 ChemDiv3_013233 Fc1ccccc1CN(Cc2ccccc2)C(=S)NCC(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J12 compound treatment 0.285 0.0702 1.0 0.29 0.0665 1.12 1.4994 0.9986 3121461 ChemDiv3_013234 CCOC(=O)N1CCN(CC1)C(=O)C2CCN(CC2)S(=O)(=O)N(CC)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J13 compound treatment 0.238 0.0232 0.33 0.238 0.0145 0.24 0.4069 0.9885 3121462 ChemDiv3_013235 COC(=O)c1cnn2c(NC3CCCCC3)c([nH]c12)c4cccc(Br)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J14 compound treatment 0.26 0.0452 0.65 0.311 0.0875 1.47 1.4957 0.932 3037793 ChemDiv3_013236 CC1CCC(CC1)NC(=O)c2ccccc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J15 compound treatment 0.296 0.0812 1.16 0.276 0.0525 0.88 1.4445 0.9907 3037794 ChemDiv3_013237 CCCNC(=O)c1c(C)cc(=O)oc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J16 compound treatment 0.276 0.0612 0.88 0.229 0.00552 0.09 0.6844 0.7776 3121463 ChemDiv3_013238 CCC(Sc1ncccc1C(=O)OC(C)C)C(=O)NCc2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J17 compound treatment 0.253 0.0382 0.55 0.228 0.00452 0.08 0.4399 0.7976 3121464 ChemDiv3_013239 O=C(NC1CCCC1)c2ccc3SCC(=O)N(Cc4ccccc4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J18 compound treatment 0.299 0.0842 1.2 0.275 0.0515 0.86 1.463 0.9868 3037796 ChemDiv3_013240 CCOC(=O)c1cccnc1SC(CC)C(=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J19 compound treatment 0.303 0.0882 1.26 0.241 0.0175 0.29 1.0999 0.8491 3121465 ChemDiv3_013241 CCN1C(=O)CSc2ccc(cc12)C(=O)NCCc3ccc(OC)c(OC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J20 compound treatment 0.259 0.0442 0.63 0.242 0.0185 0.31 0.6667 0.9465 3121466 ChemDiv3_013242 Nc1c(sc2ccc(cc12)S(=O)(=O)N3CCCCC3)C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J21 compound treatment 0.247 0.0322 0.46 0.266 0.0425 0.71 0.8302 0.9775 3037799 ChemDiv3_013243 CCOc1ccc(NC(=O)CN2C(=O)C3(OCCCO3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J22 compound treatment 0.209 -0.00581 -0.08 0.252 0.0285 0.48 0.2797 0.5758 3121467 ChemDiv3_013244 CCc1ccccc1NC(=S)N(Cc2cccc(C)c2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J23 mock treatment 0.223 0.00819 0.12 0.264 0.0405 0.68 0.5637 0.8169 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 J24 mock treatment 0.216 0.00119 0.02 0.212 -0.0115 -0.19 -0.1242 -0.642 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K01 compound treatment 0.249 0.0342 0.49 0.251 0.0275 0.46 0.6724 0.9996 1654888 ChemDiv3_013245 Cc1cccc(c1)n2cnc3cc(ccc23)C(=O)NCCC4=CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K02 compound treatment 0.216 0.00119 0.02 0.229 0.00552 0.09 0.0775 0.8236 3121468 ChemDiv3_013246 COC(=O)c1ccc(/C=C\2/Oc3ccccc3N(Cc4ccccc4F)C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K03 compound treatment 0.272 0.0572 0.82 0.293 0.0695 1.17 1.4035 0.9849 1583889 ChemDiv3_013247 CCN(CC)c1ccc(CNC(CC(=O)O)c2c[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K04 compound treatment 0.259 0.0442 0.63 0.262 0.0385 0.65 0.9041 0.9999 3036708 ChemDiv3_013248 Fc1cccc(CN2C(=O)CS(=O)c3ccc(cc23)C(=O)NCc4ccc(Cl)cc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K05 compound treatment 0.249 0.0342 0.49 0.251 0.0275 0.46 0.6724 0.9996 3036709 ChemDiv3_013249 COC(=O)c1ccc2Sc3ccc(C)cc3C(=Nc2c1)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K06 compound treatment 0.269 0.0542 0.78 0.25 0.0265 0.45 0.8628 0.9653 3036711 ChemDiv3_013250 C/C(=N\N)/c1c(C)cc(C)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K07 compound treatment 0.291 0.0762 1.09 0.274 0.0505 0.85 1.3702 0.9923 3036713 ChemDiv3_013251 O=S1(=O)CC2(CCCCCCC21)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K08 compound treatment 0.282 0.0672 0.96 0.276 0.0525 0.88 1.3029 0.9991 3036714 ChemDiv3_013252 OC(=O)c1ccc2SCCN(Cc3ccc(Cl)cc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K09 compound treatment 0.271 0.0562 0.8 0.299 0.0755 1.27 1.4646 0.9758 3036716 ChemDiv3_013253 COc1cc(CN(C2CCCC2)C(=S)NCC(=O)O)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K10 compound treatment 0.277 0.0622 0.89 0.278 0.0545 0.91 1.276 0.9999 3036718 ChemDiv3_013254 OC(=O)c1[nH]c2ccccc2c1/C=N/Cc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K11 compound treatment 0.266 0.0512 0.73 0.274 0.0505 0.85 1.1173 0.9973 3036719 ChemDiv3_013255 COC(=O)c1ccc2Sc3ccccc3C(=O)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K12 compound treatment 0.233 0.0182 0.26 0.241 0.0175 0.29 0.3919 0.9982 3121469 ChemDiv3_013256 CC1CCC(CC1)NC(=O)C2N(C(=O)c3c(C)n(C)c(C)c23)c4ccc(Br)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K13 compound treatment 0.252 0.0372 0.53 0.271 0.0475 0.8 0.9401 0.9806 3036721 ChemDiv3_013257 CC(C)(C)c1ccc2OCC(=O)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K14 compound treatment 0.269 0.0542 0.78 0.261 0.0375 0.63 0.9934 0.9947 1188609 ChemDiv3_013258 CCc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K15 compound treatment 0.271 0.0562 0.8 0.275 0.0515 0.86 1.1798 0.9993 3036724 ChemDiv3_013259 CCOC(=O)CN1N=C(CCC1=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K16 compound treatment 0.282 0.0672 0.96 0.239 0.0155 0.26 0.8638 0.8674 1398475 ChemDiv3_013260 O=C(NC1CCCCCC1)c2ccc3SCC(=O)Nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K17 compound treatment 0.226 0.0112 0.16 0.236 0.0125 0.21 0.2618 0.991 3121470 ChemDiv3_013261 Clc1ccccc1CN2C(=O)COc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K18 compound treatment 0.275 0.0602 0.86 0.224 5.16E-4 0.01 0.6149 0.7142 3036726 ChemDiv3_013262 CC(=C(C#N)C#N)Nc1cc(C)ccn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K19 compound treatment 0.266 0.0512 0.73 0.231 0.00752 0.13 0.607 0.8169 3121471 ChemDiv3_013263 O=C(NCc1ccc2OCOc2c1)c3ccc(cc3)N4CCCC4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K20 compound treatment 0.253 0.0382 0.55 0.232 0.00852 0.14 0.4874 0.8631 3121472 ChemDiv3_013264 O=C(CSc1ncnc2c3ccccc3sc12)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K21 compound treatment 0.254 0.0392 0.56 0.271 0.0475 0.8 0.9603 0.9851 3036728 ChemDiv3_013265 COc1ccc2OC(C)(C)CC(=O)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K22 compound treatment 0.226 0.0112 0.16 0.248 0.0245 0.41 0.4042 0.9154 1036234 ChemDiv3_013266 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K23 mock treatment 0.198 -0.0168 -0.24 0.244 0.0205 0.34 0.0735 0.175 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 K24 mock treatment 0.231 0.0162 0.23 0.21 -0.0135 -0.23 0.0038 0.0116 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L01 compound treatment 0.246 0.0312 0.45 0.218 -0.00548 -0.09 0.2504 0.5497 3121647 ChemDiv3_013267 CC1CCCCC1NC(=O)c2cnn3c(cc(nc23)c4ccccc4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L02 compound treatment 0.234 0.0192 0.27 0.235 0.0115 0.19 0.3308 0.9853 3036731 ChemDiv3_013268 CCCNC(=O)c1cc(=O)n(Cc2ccc(Cl)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L03 compound treatment 0.252 0.0372 0.53 0.224 5.16E-4 0.01 0.3823 0.7185 3121648 ChemDiv3_013269 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCc3ccccc3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L04 compound treatment 0.267 0.0522 0.75 0.296 0.0725 1.22 1.3885 0.9725 3036733 ChemDiv3_013270 O=C(NCCCN1CCCCC1)c2ccc3SCC(=O)Nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L05 compound treatment 0.263 0.0482 0.69 0.248 0.0245 0.41 0.7784 0.9696 3121649 ChemDiv3_013271 Cc1ccc(CNC(=O)c2cnn3c(O)cc(CSc4ccc(Cl)cc4)nc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L06 compound treatment 0.303 0.0882 1.26 0.247 0.0235 0.39 1.1711 0.886 3036792 ChemDiv3_013272 O=C(NCc1ccccn1)c2cc(nc3ccccc23)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L07 compound treatment 0.253 0.0382 0.55 0.22 -0.00348 -0.06 0.345 0.6278 3036794 ChemDiv3_013273 O=C(NCc1cccs1)c2cc(nc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L08 compound treatment 0.311 0.0962 1.38 0.306 0.0825 1.38 1.9522 1.0 3036795 ChemDiv3_013274 Cc1ccccc1Cc2c(C)nc3c(cnn3c2C)C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L09 compound treatment 0.256 0.0412 0.59 0.283 0.0595 1.0 1.123 0.9683 3036796 ChemDiv3_013275 CC1CCCC(NC(=O)CNC(=S)N(Cc2ccc(F)cc2)C3CCCCC3)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L10 compound treatment 0.228 0.0132 0.19 0.306 0.0825 1.38 1.1128 0.7961 3036798 ChemDiv3_013276 CC1CCCCC1NS(=O)(=O)c2ccc3oc(C(=O)O)c(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L11 compound treatment 0.303 0.0882 1.26 0.236 0.0125 0.21 1.0406 0.8137 3036799 ChemDiv3_013277 Cc1ccc(CN2C(=O)CSc3ccc(cc23)C(=O)NCC4CCCO4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L12 compound treatment 0.257 0.0422 0.6 0.267 0.0435 0.73 0.9432 0.9955 3121650 ChemDiv3_013278 O=C(NCc1ccccc1)C2CCN(CC2)S(=O)(=O)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L13 compound treatment 0.269 0.0542 0.78 0.289 0.0655 1.1 1.3257 0.9854 3121651 ChemDiv3_013279 Fc1ccc(Sc2cc(C(=O)NCCCN3CCCCC3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L14 compound treatment 0.3 0.0852 1.22 0.297 0.0735 1.23 1.7342 1.0 1537317 ChemDiv3_013280 OC(=O)c1ccccc1C(=O)NCCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L15 compound treatment 0.266 0.0512 0.73 0.234 0.0105 0.18 0.6426 0.8531 3036801 ChemDiv3_013281 Cc1nc2nc(SCC(=O)Nc3ccccc3C(F)(F)F)nn2c(C)c1Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L16 compound treatment 0.289 0.0742 1.06 0.29 0.0665 1.12 1.5398 0.9997 3121652 ChemDiv3_013282 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)Nc3cccc(Cl)c3)c(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L17 compound treatment 0.22 0.00519 0.07 0.27 0.0465 0.78 0.6046 0.7709 3036803 ChemDiv3_013283 O=C(NCCc1ccccc1)c2ccc3SCC(=O)N(Cc4ccccc4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L18 compound treatment 0.303 0.0882 1.26 0.289 0.0655 1.1 1.6696 0.9977 3121653 ChemDiv3_013284 CCOC(=O)c1cccnc1SCC(=O)NC(C)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L19 compound treatment 0.319 0.104 1.49 0.283 0.0595 1.0 1.7602 0.9811 3121654 ChemDiv3_013285 CCCNC(=O)c1cnn2c(C)c(Cc3ccccc3)c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L20 compound treatment 0.261 0.0462 0.66 0.267 0.0435 0.73 0.9837 0.9987 3036805 ChemDiv3_013286 Cc1cccc(CN(C(=O)Nc2ccc(Cl)c(Cl)c2)c3ccccn3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L21 compound treatment 0.226 0.0112 0.16 0.296 0.0725 1.22 0.9738 0.7933 1251283 ChemDiv3_013287 CC1CCN(CN2C(=O)C3(OCCCO3)c4ccccc24)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L22 compound treatment 0.246 0.0312 0.45 0.269 0.0455 0.76 0.8557 0.9672 3121655 ChemDiv3_013288 CC(=O)Nc1cc(ccc1Sc2ccc(F)cc2)C(=O)N3CCN(CC3)c4cc(Cl)ccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L23 mock treatment 0.234 0.0192 0.27 0.217 -0.00648 -0.11 0.1172 0.3968 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 L24 mock treatment 0.214 -8.06E-4 -0.01 0.209 -0.0145 -0.24 -0.1801 -0.7398 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M01 compound treatment 0.194 -0.0208 -0.3 0.202 -0.0215 -0.36 -0.4654 -0.9955 1449683 ChemDiv3_013289 CCc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M02 compound treatment 0.238 0.0232 0.33 0.194 -0.0295 -0.49 -0.1153 -0.1936 3121656 ChemDiv3_013290 COC(=O)c1cc2CN(Cc2s1)C3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M03 compound treatment 0.277 0.0622 0.89 0.277 0.0535 0.9 1.2642 1.0 1440916 ChemDiv3_013291 OC(=O)c1ccc(CNCc2cccc(Oc3ccccc3)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M04 compound treatment 0.304 0.0892 1.28 0.307 0.0835 1.4 1.8933 0.9989 3121657 ChemDiv3_013292 Clc1ccc(CNC(=O)Cn2c3CCCCc3c(cc2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M05 compound treatment 0.259 0.0442 0.63 0.274 0.0505 0.85 1.0465 0.9895 3036809 ChemDiv3_013293 OC(=O)CCNCc1cccs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M06 compound treatment 0.284 0.0692 0.99 0.239 0.0155 0.26 0.884 0.8638 3121658 ChemDiv3_013294 COc1ccc(/C=C\2/Oc3ccccc3N(CC(=O)O)C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M07 compound treatment 0.29 0.0752 1.08 0.279 0.0555 0.93 1.4194 0.9974 3036811 ChemDiv3_013295 CCOC(=O)C1CCC(CNCc2ccccc2C)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M08 compound treatment 0.301 0.0862 1.23 0.262 0.0385 0.65 1.3289 0.9546 3121659 ChemDiv3_013296 COc1ccc(cc1OC)C2OC(=O)CC2C(=O)NCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M09 compound treatment 0.298 0.0832 1.19 0.304 0.0805 1.35 1.797 0.998 3036813 ChemDiv3_013297 CCOC(=O)c1ccc2Sc3ccccc3C(=O)N(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M10 compound treatment 0.04 -0.175 -2.5 0.042 -0.181 -3.05 -3.9219 -0.9952 3121660 ChemDiv3_013298 Cc1cc(C)c2c(=O)n(CC(=O)Nc3ccc(Cl)cc3)sc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M11 compound treatment 0.272 0.0572 0.82 0.283 0.0595 1.0 1.2848 0.9951 3036814 ChemDiv3_013299 OC(=O)CCCc1c([nH]c2ccccc12)[n+]3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M12 compound treatment 0.296 0.0812 1.16 0.299 0.0755 1.27 1.7174 0.999 3121661 ChemDiv3_013300 COc1ccc(cc1)C2SCC(N2C(=O)C)C(=O)NCc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M13 compound treatment 0.314 0.0992 1.42 0.295 0.0715 1.2 1.852 0.9965 3121662 ChemDiv3_013301 COC(=O)c1ccc(N2CCCC2)c(NS(=O)(=O)c3ccc(C)cc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M14 compound treatment 0.233 0.0182 0.26 0.239 0.0155 0.26 0.3682 1.0 3036877 ChemDiv3_013302 CCC(Sc1nc2n[nH]c(C)c2c(=N)n1c3cccc(Cl)c3C)C(=O)N(CC)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M15 compound treatment 0.248 0.0332 0.47 0.204 -0.0195 -0.33 0.1045 0.1812 3121663 ChemDiv3_013303 OC(=O)CN1N=C(CCC1=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M16 compound treatment 0.303 0.0882 1.26 0.287 0.0635 1.07 1.6458 0.9965 1224886 ChemDiv3_013304 O=C(NCCC1=CCCCC1)c2ccc3SCC(=O)Nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M17 compound treatment 0.288 0.0732 1.05 0.255 0.0315 0.53 1.1143 0.95 3037807 ChemDiv3_013305 Fc1ccc(CN2C(=O)/C(=C\C(=O)NCc3ccccc3)/Sc4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M18 compound treatment 0.244 0.0292 0.42 0.19 -0.0335 -0.56 -0.1021 -0.1459 1162072 ChemDiv3_013306 Nc1cc(ccc1Sc2ccccc2C(=O)O)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M19 compound treatment 0.231 0.0162 0.23 0.246 0.0225 0.38 0.431 0.9724 3037809 ChemDiv3_013307 CCn1cc(CN(Cc2ccccc2)C(=S)Nc3cc(C)ccc3C)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M20 compound treatment 0.272 0.0572 0.82 0.231 0.00752 0.13 0.6677 0.8066 3037811 ChemDiv3_013308 CCc1ccc(NC(=O)CSc2ncnc3c4ccccc4sc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M21 compound treatment 0.288 0.0732 1.05 0.247 0.0235 0.39 1.0194 0.9111 1920457 ChemDiv3_013309 Clc1ccc(CNC(=O)c2ccc(Br)o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M22 compound treatment 0.228 0.0132 0.19 0.236 0.0125 0.21 0.282 0.9986 3037812 ChemDiv3_013310 Cc1nc2c(cnn2c(C)c1Cc3c(F)cccc3Cl)C(=O)NCc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M23 mock treatment 0.233 0.0182 0.26 0.231 0.00752 0.13 0.2732 0.9447 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 M24 mock treatment 0.225 0.0102 0.15 0.22 -0.00348 -0.06 0.0618 0.3931 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N01 compound treatment 0.249 0.0342 0.49 0.265 0.0415 0.7 0.8386 0.985 3121664 ChemDiv3_013311 OC(=O)c1cnn2c(cc(nc12)c3ccco3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N02 compound treatment 0.233 0.0182 0.26 0.239 0.0155 0.26 0.3682 1.0 3121665 ChemDiv3_013312 Cc1ccc(Cn2c(=O)cc(C(=O)NCc3cccs3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N03 compound treatment 0.293 0.0782 1.12 0.252 0.0285 0.48 1.1293 0.9283 3037816 ChemDiv3_013313 COC(CNC(=O)c1cnn2c(C)c(Cc3c(C)cc(C)cc3C)c(C)nc12)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N04 compound treatment 0.235 0.0202 0.29 0.257 0.0335 0.56 0.602 0.952 3121666 ChemDiv3_013314 O=C(NCCCN1CCCC1)c2cc(nc3ccccc23)c4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N05 compound treatment 0.255 0.0402 0.57 0.206 -0.0175 -0.29 0.199 0.3083 3037818 ChemDiv3_013315 CCc1ccc(NC(=S)N(CCN2CCOCC2)Cc3ccccc3F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N06 compound treatment 0.306 0.0912 1.3 0.273 0.0495 0.83 1.51 0.9763 3121667 ChemDiv3_013316 O=C(N1CCC2(CC1)OCCO2)c3cc(nc4ccccc34)c5cccnc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N07 compound treatment 0.269 0.0542 0.78 0.269 0.0455 0.76 1.0883 1.0 1712820 ChemDiv3_013317 O=C(NCCc1ccccc1)c2cc(nc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N08 compound treatment 0.319 0.104 1.49 0.287 0.0635 1.07 1.8077 0.9865 1588871 ChemDiv3_013318 Cc1ccc(Cc2c(C)nc3c(cnn3c2C)C(=O)NC4CCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N09 compound treatment 0.315 0.1 1.43 0.292 0.0685 1.15 1.8265 0.994 3036735 ChemDiv3_013319 Fc1ccccc1CN(C2CCCCC2)C(=S)NCC(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N10 compound treatment 0.291 0.0762 1.09 0.269 0.0455 0.76 1.3108 0.9849 1409092 ChemDiv3_013320 OC(=O)c1cccnc1SCC(=O)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N11 compound treatment 0.303 0.0882 1.26 0.302 0.0785 1.32 1.8238 0.9998 3036737 ChemDiv3_013321 CCCCN(C)c1ccc(cc1NC(=S)Nc2cccc(C)c2)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N12 compound treatment 0.248 0.0332 0.47 0.283 0.0595 1.0 1.0421 0.9422 1882367 ChemDiv3_013322 Cc1ccc(cc1C)c2cc(C(=O)NCC=C)c3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N13 compound treatment 0.303 0.0882 1.26 0.295 0.0715 1.2 1.7408 0.9997 3036739 ChemDiv3_013323 Cc1cc(=O)oc(C)c1C(=O)NCC2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N14 compound treatment 0.243 0.0282 0.4 0.284 0.0605 1.02 1.0034 0.9181 3036740 ChemDiv3_013324 OC(=O)c1ccccc1C(=O)NCC2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N15 compound treatment 0.255 0.0402 0.57 0.254 0.0305 0.51 0.7687 0.9983 3121668 ChemDiv3_013325 COc1ccc(OC)c(NC(=O)CSc2nc3nc(C)c(Cc4ccccc4)c(C)n3n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N16 compound treatment 0.31 0.0952 1.36 0.304 0.0805 1.35 1.9184 1.0 3036742 ChemDiv3_013326 Cc1ccc(CNC(=O)C2CNc3cc(C)ccc3O2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N17 compound treatment 0.271 0.0562 0.8 0.277 0.0535 0.9 1.2035 0.9985 3121669 ChemDiv3_013327 CC(C)NC(=O)c1ccc2SCC(=O)N(Cc3ccccc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N18 compound treatment 0.22 0.00519 0.07 0.236 0.0125 0.21 0.2011 0.9024 3121670 ChemDiv3_013328 CC(C)CCNC(=O)C1CCN(CC1)c2nc3ccccc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N19 compound treatment 0.241 0.0262 0.37 0.23 0.00652 0.11 0.3423 0.8769 3036744 ChemDiv3_013329 COc1cc(cc(OC)c1OC)C(=O)NCCC(=O)NC2CCC(C)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N20 compound treatment 0.235 0.0202 0.29 0.275 0.0515 0.86 0.8156 0.8947 3121671 ChemDiv3_013330 Cc1ccc(NC(=S)N(Cc2cccc(C)c2)c3ccccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N21 compound treatment 0.287 0.0722 1.03 0.218 -0.00548 -0.09 0.6651 0.6415 3036747 ChemDiv3_013331 CC(C)N(C)C1CCN(CC1)C(=S)Nc2ccccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N22 compound treatment 0.221 0.00619 0.09 0.193 -0.0305 -0.51 -0.2991 -0.5761 3121672 ChemDiv3_013332 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N23 mock treatment 0.25 0.0352 0.5 0.23 0.00652 0.11 0.4333 0.8411 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 N24 mock treatment 0.224 0.00919 0.13 0.233 0.00952 0.16 0.2059 0.9953 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O01 compound treatment 0.241 0.0262 0.37 0.233 0.00952 0.16 0.3779 0.9278 1585487 ChemDiv3_013333 COc1ccc(cc1)S(=O)(=O)NCC2CCC(CC2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O02 compound treatment 0.243 0.0282 0.4 0.243 0.0195 0.33 0.5168 0.9947 3036749 ChemDiv3_013334 COC(=O)c1cc2CN(Cc3ccc(Cl)cc3)Cc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O03 compound treatment 0.247 0.0322 0.46 0.281 0.0575 0.97 1.0082 0.9427 1541675 ChemDiv3_013335 CC(C)C(CC(=O)O)NCc1ccccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O04 compound treatment 0.23 0.0152 0.22 0.248 0.0245 0.41 0.4446 0.9555 3036751 ChemDiv3_013336 O=C(CN1CCOc2ccccc12)NC3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O05 compound treatment 0.223 0.00819 0.12 0.231 0.00752 0.13 0.1721 0.9993 3121851 ChemDiv3_013337 OC(=O)CNC(=S)N(Cc1cccs1)C2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O06 compound treatment 0.117 -0.0978 -1.4 0.105 -0.118 -1.99 -2.3954 -0.9852 3121852 ChemDiv3_013338 OC(=O)c1ccc2S/C(=C/c3ccccc3)/C(=O)N(Cc4ccc(F)cc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O07 compound treatment 0.22 0.00519 0.07 0.265 0.0415 0.7 0.5452 0.7781 3036753 ChemDiv3_013339 CCOC(=O)C1CCC(CNCc2ccc(OC)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O08 compound treatment 0.248 0.0332 0.47 0.264 0.0405 0.68 0.8166 0.9846 3121853 ChemDiv3_013340 CC1CCC2(OC(=O)C(=C2)C)C(C1)C(=O)NCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O09 compound treatment 0.233 0.0182 0.26 0.196 -0.0275 -0.46 -0.1422 -0.2684 3036755 ChemDiv3_013341 CN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O10 compound treatment 0.256 0.0412 0.59 0.254 0.0305 0.51 0.7788 0.9976 3121854 ChemDiv3_013342 COC(=O)c1ccc2Sc3ccccc3C(=S)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O11 compound treatment 0.259 0.0442 0.63 0.255 0.0315 0.53 0.821 0.9961 1381204 ChemDiv3_013343 CCOC(=O)C1CCCN(C1)C(=S)Nc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O12 compound treatment 0.267 0.0522 0.75 0.244 0.0205 0.34 0.7714 0.9383 3036816 ChemDiv3_013344 COC(CNC(=O)c1cc2CSCc2s1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O13 compound treatment 0.259 0.0442 0.63 0.235 0.0115 0.19 0.5837 0.883 3036818 ChemDiv3_013345 NC(=O)c1cccn1Cc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O14 compound treatment 0.181 -0.0338 -0.48 0.264 0.0405 0.68 0.1389 0.1665 1460833 ChemDiv3_013346 Fc1ccccc1CSCC(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O15 compound treatment 0.244 0.0292 0.42 0.217 -0.00648 -0.11 0.2183 0.5059 1003082 ChemDiv3_013347 OC(=O)CCC(=O)c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O16 compound treatment 0.229 0.0142 0.2 0.227 0.00352 0.06 0.1853 0.8764 1696468 ChemDiv3_013348 OC(=O)CCS(=O)(=O)Cc1ccccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O17 compound treatment 0.246 0.0312 0.45 0.257 0.0335 0.56 0.7133 0.9934 3036820 ChemDiv3_013349 Fc1ccc(CN2C(=O)/C(=C\C(=O)N3CCCC3)/Sc4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O18 compound treatment 0.188 -0.0268 -0.38 0.228 0.00452 0.08 -0.2175 -0.5566 1566405 ChemDiv3_013350 NC(=O)c1cc(ccc1F)S(=O)(=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O19 compound treatment 0.219 0.00419 0.06 0.268 0.0445 0.75 0.5707 0.7614 3036822 ChemDiv3_013351 COC(=O)c1cnn(C(=O)c2ccccc2)c1NC(=S)Nc3ccc(C)cc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O20 compound treatment 0.175 -0.0398 -0.57 0.236 0.0125 0.21 -0.2541 -0.4186 3036823 ChemDiv3_013352 CCN(C(=O)CSc1ncnc2c3ccccc3sc12)c4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O21 compound treatment 0.24 0.0252 0.36 0.221 -0.00248 -0.04 0.2253 0.6212 3121855 ChemDiv3_013353 COC(=O)c1ccc(cc1)C2N(Cc3ccc(F)cc3)CCCN2Cc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O22 compound treatment 0.205 -0.00981 -0.14 0.217 -0.00648 -0.11 -0.1761 -0.9921 3036824 ChemDiv3_013354 COC(=O)c1cnn2c(O)c(C(C)C)c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O23 mock treatment 0.175 -0.0398 -0.57 0.229 0.00552 0.09 -0.3371 -0.5845 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 O24 mock treatment 0.189 -0.0258 -0.37 0.233 0.00952 0.16 -0.1481 -0.3682 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P01 compound treatment 0.285 0.0702 1.0 0.243 0.0195 0.33 0.9416 0.8916 3121856 ChemDiv3_013355 CC1CCCC(NC(=O)c2ccc3SCC(=O)Nc3c2)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P02 compound treatment 0.282 0.0672 0.96 0.259 0.0355 0.6 1.1011 0.9736 3121857 ChemDiv3_013356 CCCNC(=O)c1cc(=O)n(Cc2ccc(C)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P03 compound treatment 0.239 0.0242 0.35 0.279 0.0555 0.93 0.9036 0.9091 3036828 ChemDiv3_013357 COc1cccc(CNC(=O)c2cnn3c(C)c(Cc4c(C)cc(C)cc4C)c(C)nc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P04 compound treatment 0.234 0.0192 0.27 0.27 0.0465 0.78 0.7462 0.9016 3121858 ChemDiv3_013358 O=C(CCC1CC(=O)Nc2ccccc12)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P05 compound treatment 0.217 0.00219 0.03 0.23 0.00652 0.11 0.0995 0.8747 3121859 ChemDiv3_013359 COc1cccc(NC(=S)N(Cc2ccc(C)o2)Cc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P06 compound treatment 0.255 0.0402 0.57 0.241 0.0175 0.29 0.6144 0.9515 3036831 ChemDiv3_013360 O=C(NC1CC1)c2cc(nc3ccccc23)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P07 compound treatment 0.258 0.0432 0.62 0.229 0.00552 0.09 0.5023 0.8041 3121860 ChemDiv3_013361 COC(CNC(=O)c1cc(nc2ccccc12)c3ccccc3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P08 compound treatment 0.236 0.0212 0.3 0.261 0.0375 0.63 0.6596 0.9438 1397765 ChemDiv3_013362 Cc1nc2c(cnn2c(C)c1Cc3ccc(Cl)cc3)C(=O)N4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P09 compound treatment 0.254 0.0392 0.56 0.218 -0.00548 -0.09 0.3313 0.5832 3121861 ChemDiv3_013363 Cc1ccc(CN(Cc2ccccc2)C(=S)NCC(=O)N3CCC4(CC3)OCCO4)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P10 compound treatment 0.247 0.0322 0.46 0.258 0.0345 0.58 0.7353 0.9935 3121862 ChemDiv3_013364 OC(=O)c1cccnc1SCC(=O)NCCC2=CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P11 compound treatment 0.234 0.0192 0.27 0.237 0.0135 0.23 0.3545 0.9955 3036835 ChemDiv3_013365 CCN(C(=O)CSc1nc2nc(C)c(Cc3cc(C)ccc3C)c(C)n2n1)c4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P12 compound treatment 0.249 0.0342 0.49 0.249 0.0255 0.43 0.6487 0.9978 3121863 ChemDiv3_013366 O=C(CC(C(=O)N1CCc2ccccc12)n3ccnc3)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P13 compound treatment 0.26 0.0452 0.65 0.281 0.0575 0.97 1.1397 0.981 3036837 ChemDiv3_013367 Cc1cc(=O)oc(C)c1C(=O)NC2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P14 compound treatment 0.219 0.00419 0.06 0.241 0.0175 0.29 0.2503 0.8342 3121864 ChemDiv3_013368 O=C(CC(C(=O)N1CCc2ccccc12)n3ccnc3)N4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P15 compound treatment 0.269 0.0542 0.78 0.239 0.0155 0.26 0.7323 0.8955 3121865 ChemDiv3_013369 CCc1ccc(cc1)N2C(=O)C3CCCN3C2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P16 compound treatment 0.262 0.0472 0.68 0.209 -0.0145 -0.24 0.3054 0.4257 3036880 ChemDiv3_013370 COc1cccc(NC(=O)c2oc3ccc(cc3c2C)S(=O)(=O)N4CC(C)CC(C)C4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P17 compound treatment 0.236 0.0212 0.3 0.231 0.00752 0.13 0.3036 0.9245 3036881 ChemDiv3_013371 CC(C)NC(=O)c1ccc2Sc3ccccc3C(=O)N(Cc4cccc(C)c4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P18 compound treatment 0.263 0.0482 0.69 0.232 0.00852 0.14 0.5885 0.8359 1224632 ChemDiv3_013372 CCC(C)NC(=O)C1CCCN(C1)S(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P19 compound treatment 0.275 0.0602 0.86 0.264 0.0405 0.68 1.0897 0.9932 3036883 ChemDiv3_013373 COc1cc(cc(OC)c1OC)C(=O)NCCC(=O)NC2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P20 compound treatment 0.239 0.0242 0.35 0.258 0.0345 0.58 0.6543 0.9697 3036885 ChemDiv3_013374 Cn1cc(CCC(=O)NC2CCCCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P21 compound treatment 0.232 0.0172 0.25 0.257 0.0335 0.56 0.5717 0.9311 3036887 ChemDiv3_013375 CCc1ccc(NC(=S)N2CCC(CC2)N(C)C(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P22 compound treatment 0.253 0.0382 0.55 0.23 0.00652 0.11 0.4636 0.8322 3121866 ChemDiv3_013376 CCC(C)NC(=O)c1ccc(Sc2ccc(Cl)cc2)c(NC(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P23 mock treatment 0.217 0.00219 0.03 0.238 0.0145 0.24 0.1945 0.7916 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2038 P24 mock treatment 0.184 -0.0308 -0.44 0.198 -0.0255 -0.43 -0.614 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A01 compound treatment 0.209 -0.0112 -0.16 0.275 0.0346 0.58 0.2967 0.493 3036889 ChemDiv3_013377 CCN(C(=O)CSc1ncccc1C(=O)OC(C)C)c2cccc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A02 compound treatment 0.203 -0.0172 -0.25 0.243 0.00256 0.04 -0.1437 -0.5749 3121867 ChemDiv3_013378 Cc1cccc(NC(=S)N(CCc2ccncc2)C3CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A03 compound treatment 0.201 -0.0192 -0.27 0.226 -0.0144 -0.24 -0.3657 -0.998 3121868 ChemDiv3_013379 CC1CCCC(C)N1CCNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A04 compound treatment 0.215 -0.00522 -0.07 0.249 0.00856 0.14 0.0488 0.3016 3036891 ChemDiv3_013380 CC(C)CCNC(=O)C1CCN(CC1)C(=O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A05 compound treatment 0.187 -0.0332 -0.48 0.257 0.0166 0.28 -0.1394 -0.2533 3121869 ChemDiv3_013381 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A06 compound treatment 0.193 -0.0272 -0.39 0.274 0.0336 0.56 0.123 0.1797 3036894 ChemDiv3_013382 O=C(CN1N=C(CCC1=O)c2ccccc2)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A07 compound treatment 0.217 -0.00322 -0.05 0.256 0.0156 0.26 0.1521 0.5736 3121870 ChemDiv3_013383 CCC(C)NC(=O)c1ccc(CS(=O)(=O)Cc2ccc(Cl)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A08 compound treatment 0.197 -0.0232 -0.33 0.272 0.0316 0.53 0.1397 0.2235 3036896 ChemDiv3_013384 O=C(NCCC1=CCCCC1)C2CCN(CC2)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A09 compound treatment 0.213 -0.00722 -0.1 0.256 0.0156 0.26 0.1117 0.3976 3121871 ChemDiv3_013385 COc1ccc(Br)cc1CNC(=O)C2CCCN(C2)c3nc4ccccc4o3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A10 compound treatment 0.234 0.0138 0.2 0.258 0.0176 0.29 0.3478 0.9809 3036897 ChemDiv3_013386 Cc1ccc(CSCCC(=O)N2CCN(CC2)c3cccc(C)c3C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A11 compound treatment 0.23 0.00978 0.14 0.216 -0.0244 -0.41 -0.1911 -0.441 3121872 ChemDiv3_013387 CC(C)CCN(C)C1CCN(CC1)S(=O)(=O)c2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A12 compound treatment 0.216 -0.00422 -0.06 0.222 -0.0184 -0.31 -0.2615 -0.8294 3036900 ChemDiv3_013388 CS(=O)(=O)N1CCCC(C1)C(=O)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A13 compound treatment 0.211 -0.00922 -0.13 0.222 -0.0184 -0.31 -0.3121 -0.9277 3121873 ChemDiv3_013389 O=C(CNC(=O)c1cccs1)N2CCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A14 compound treatment 0.198 -0.0222 -0.32 0.213 -0.0274 -0.46 -0.5504 -0.9836 3121874 ChemDiv3_013390 CCS(=O)(=O)N1CCC(CC1)C(=O)N2CCc3ccccc3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A15 compound treatment 0.209 -0.0112 -0.16 0.207 -0.0334 -0.56 -0.5103 -0.8743 3036903 ChemDiv3_013391 FC(F)(F)c1cccc(c1)S(=O)(=O)N(CCCN2CCOCC2)Cc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A16 compound treatment 0.219 -0.00122 -0.02 0.243 0.00256 0.04 0.0181 0.3897 3121875 ChemDiv3_013392 O=C(CN1C(=O)COc2ccccc12)NCCN3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A17 compound treatment 0.206 -0.0142 -0.2 0.235 -0.00544 -0.09 -0.2083 -0.9346 3036942 ChemDiv3_013393 CCC1Oc2ccccc2N(CC(=O)N3CCOCC3)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A18 compound treatment 0.217 -0.00322 -0.05 0.215 -0.0254 -0.43 -0.3344 -0.7788 3036943 ChemDiv3_013394 O=C(NCCc1ccccc1)C2CN(C3CCCC3)C(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A19 compound treatment 0.201 -0.0192 -0.27 0.245 0.00456 0.08 -0.1402 -0.4914 3036945 ChemDiv3_013395 O=C(CCN1C(=O)COc2ccccc12)NC3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A20 compound treatment 0.196 -0.0242 -0.35 0.217 -0.0234 -0.39 -0.5231 -0.998 3036946 ChemDiv3_013396 Cc1ccc(cc1)c2ccc(=O)n(CC(=O)N3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A21 compound treatment 0.228 0.00778 0.11 0.227 -0.0134 -0.23 -0.0808 -0.3212 3036947 ChemDiv3_013397 COCCN(C1CCN(CC1)C(C)C)C(=O)Nc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A22 compound treatment 0.234 0.0138 0.2 0.238 -0.00244 -0.04 0.1105 0.5487 3036948 ChemDiv3_013398 Cc1ccccc1CSCc2ccc(o2)C(=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A23 mock treatment 0.221 7.81E-4 0.01 0.211 -0.0294 -0.49 -0.3415 -0.6909 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 A24 mock treatment 0.206 -0.0142 -0.2 0.211 -0.0294 -0.49 -0.4932 -0.923 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B01 compound treatment 0.246 0.0258 0.37 0.271 0.0306 0.51 0.6235 0.9869 3036950 ChemDiv3_013399 O=C(CCn1nc(ccc1=O)c2ccccc2)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B02 compound treatment 0.225 0.00478 0.07 0.264 0.0236 0.4 0.328 0.8173 3121876 ChemDiv3_013400 Brc1ccc2[nH]c(=O)cc(C(=O)NC3CCCC3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B03 compound treatment 0.252 0.0318 0.45 0.27 0.0296 0.5 0.6723 0.999 3122060 ChemDiv3_013401 COc1ccc(CN2CC(CC2=O)C(=O)NCCCN3CCC(C)CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B04 compound treatment 0.272 0.0518 0.74 0.266 0.0256 0.43 0.8271 0.9663 3036953 ChemDiv3_013402 C=CCNC(=O)CN1C(=O)/C(=C/c2ccccc2)/Sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B05 compound treatment 0.248 0.0278 0.4 0.27 0.0296 0.5 0.6318 0.9939 3122061 ChemDiv3_013403 CCC(C)NC(=O)C1CCC(=O)N1CCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B06 compound treatment 0.227 0.00678 0.1 0.295 0.0546 0.92 0.7161 0.7777 3122062 ChemDiv3_013404 CC1CCN(CC1)S(=O)(=O)c2ccc3nc(cc(C(=O)NCC4CCCO4)c3c2)c5cccnc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B07 compound treatment 0.238 0.0178 0.25 0.24 -4.38E-4 -0.01 0.1747 0.6864 3036955 ChemDiv3_013405 CCc1ccc(Sc2cc(C(=O)NC3CC3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B08 compound treatment 0.225 0.00478 0.07 0.295 0.0546 0.92 0.6959 0.7578 3036957 ChemDiv3_013406 CC(N(C1CCCCC1)C(=O)Nc2ccccc2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B09 compound treatment 0.238 0.0178 0.25 0.286 0.0456 0.76 0.7206 0.8941 3122063 ChemDiv3_013407 CC1CCCC(C)N1CCNC(=O)C2C3OC4(CN(Cc5ccccc5Cl)C(=O)C24)C=C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B10 compound treatment 0.249 0.0288 0.41 0.291 0.0506 0.85 0.8912 0.9448 3122064 ChemDiv3_013408 COC(CNC(=O)CN1C(=O)/C(=C\c2ccc(Cl)cc2)/Oc3ccc(cc13)C(C)(C)C)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B11 compound treatment 0.222 0.00178 0.03 0.301 0.0606 1.02 0.7368 0.7246 3036960 ChemDiv3_013409 CCCS(=O)(=O)N1CCC(CC1)C(=O)N2CCC3(CC2)OCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B12 compound treatment 0.228 0.00778 0.11 0.278 0.0376 0.63 0.5245 0.8193 3122065 ChemDiv3_013410 COCCN(C1CCN(CC1)C(=O)C)C(=S)Nc2cc(F)cc(F)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B13 compound treatment 0.247 0.0268 0.38 0.263 0.0226 0.38 0.5386 1.0 3036961 ChemDiv3_013411 CNC(=O)C1CN(CCc2ccc(C)cc2)C(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B14 compound treatment 0.236 0.0158 0.23 0.268 0.0276 0.46 0.4867 0.9456 3122066 ChemDiv3_013412 O=C(NCCC1=CCCCC1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B15 compound treatment 0.219 -0.00122 -0.02 0.251 0.0106 0.18 0.113 0.6345 3036963 ChemDiv3_013413 COC(CNC(=O)c1cc(Sc2nnc(C)s2)nc3ccccc13)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B16 compound treatment 0.17 -0.0502 -0.72 0.2 -0.0404 -0.68 -0.9878 -0.9996 3122067 ChemDiv3_013414 O=C(N1CCCCC1)c2ccc(/C=C\3/Sc4ccccc4NC3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B17 compound treatment 0.217 -0.00322 -0.05 0.248 0.00756 0.13 0.0572 0.4236 3122068 ChemDiv3_013415 CN(CCNC(=O)c1cc(Sc2nnc(C)s2)nc3ccccc13)Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B18 compound treatment 0.241 0.0208 0.3 0.285 0.0446 0.75 0.7391 0.9183 3036966 ChemDiv3_013416 Fc1cccc(Cl)c1CN2N=C(CCC2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B19 compound treatment 0.255 0.0348 0.5 0.295 0.0546 0.92 0.9993 0.9589 3122069 ChemDiv3_013417 COc1ccc(cc1)C2=NN(CC(=O)NCc3ccc(C)cc3)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B20 compound treatment 0.233 0.0128 0.18 0.263 0.0226 0.38 0.397 0.9442 3036967 ChemDiv3_013418 COc1ccccc1NC(=S)N(Cc2cccn2Cc3ccc(F)cc3Cl)Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B21 compound treatment 0.262 0.0418 0.6 0.291 0.0506 0.85 1.0227 0.9853 3036915 ChemDiv3_013419 CSc1cccc(NC(=S)NCc2cccn2C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B22 compound treatment 0.255 0.0348 0.5 0.237 -0.00344 -0.06 0.311 0.6209 3036916 ChemDiv3_013420 COc1ccc(cc1)c2ccc(=O)n(CC(=O)N(C)c3ccccc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B23 mock treatment 0.263 0.0428 0.61 0.27 0.0296 0.5 0.7835 0.9946 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 B24 mock treatment 0.23 0.00978 0.14 0.229 -0.0114 -0.19 -0.0368 -0.155 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C01 compound treatment 0.209 -0.0112 -0.16 0.251 0.0106 0.18 0.0119 0.0497 3036918 ChemDiv3_013421 COc1ccc(NC(=O)CSc2ncccc2C(=O)Oc3ccccc3Cl)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C02 compound treatment 0.202 -0.0182 -0.26 0.275 0.0346 0.58 0.2259 0.3553 3036919 ChemDiv3_013422 CCc1ccc(NC(=O)N(CCN(C)C)C(C)c2cccnc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C03 compound treatment 0.04 -0.18 -2.58 0.29 0.0496 0.83 -1.2346 -0.4558 3036920 ChemDiv3_013423 COc1ccc(CCNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C04 compound treatment 0.225 0.00478 0.07 0.234 -0.00644 -0.11 -0.028 -0.2193 3036923 ChemDiv3_013424 CN(C)C(=O)N1CCC(CC1)C(=O)NCCC2=CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C05 compound treatment 0.217 -0.00322 -0.05 0.278 0.0376 0.63 0.4132 0.6537 3122070 ChemDiv3_013425 CCC(C)NC(=O)C1CCCN(C1)S(=O)(=O)N2CCC(C)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C06 compound treatment 0.102 -0.118 -1.69 0.293 0.0526 0.88 -0.5719 -0.2998 3036970 ChemDiv3_013426 CC(C)CCNC(=O)Cn1nc(ccc1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C07 compound treatment 0.232 0.0118 0.17 0.217 -0.0234 -0.39 -0.159 -0.3715 3036971 ChemDiv3_013427 Clc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)N3CCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C08 compound treatment 0.22 -2.19E-4 0.0 0.278 0.0376 0.63 0.4436 0.7036 3036973 ChemDiv3_013428 O=C(Cn1nc(ccc1=O)c2ccccc2)NCCCN3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C09 compound treatment 0.236 0.0158 0.23 0.276 0.0356 0.6 0.5817 0.9115 3036974 ChemDiv3_013429 Cc1ccc(Cl)cc1N2CCN(CC2)C(=O)CN3C(=O)COc4ccc(cc34)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C10 compound treatment 0.263 0.0428 0.61 0.04 -0.2 -3.36 -1.9461 -0.5691 3036976 ChemDiv3_013430 COc1ccc(CNC(=O)CCSCc2ccc(C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C11 compound treatment 0.211 -0.00922 -0.13 0.251 0.0106 0.18 0.0321 0.1454 3036978 ChemDiv3_013431 Clc1cccc(CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)NCC=C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C12 compound treatment 0.224 0.00378 0.05 0.282 0.0416 0.7 0.5315 0.7597 3122071 ChemDiv3_013432 CC(C)CN(CC(C)C)S(=O)(=O)N1CCC(CC1)C(=O)NCc2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C13 compound treatment 0.234 0.0138 0.2 0.28 0.0396 0.66 0.6089 0.8791 3036981 ChemDiv3_013433 Clc1ccc(NC(=O)N(CCCN2CCOCC2)Cc3cccnc3)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C14 compound treatment 0.245 0.0248 0.35 0.257 0.0166 0.28 0.4472 0.9928 3122072 ChemDiv3_013434 CC1CCN(CC1)C(=O)CN2N=C(CCC2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C15 compound treatment 0.165 -0.0552 -0.79 0.236 -0.00444 -0.07 -0.6112 -0.7704 3036984 ChemDiv3_013435 O=S(=O)(N(CCCN1CCOCC1)Cc2cccs2)c3ccc(cc3)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C16 compound treatment 0.041 -0.179 -2.56 0.044 -0.196 -3.3 -4.144 -0.9923 3122073 ChemDiv3_013436 CC(C)CN(CC(C)C)S(=O)(=O)N1CCC(CC1)C(=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C17 compound treatment 0.239 0.0188 0.27 0.043 -0.197 -3.31 -2.1532 -0.6477 3036987 ChemDiv3_013437 O=C(C1CCN(CC1)S(=O)(=O)N2CCCCC2)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C18 compound treatment 0.041 -0.179 -2.56 0.233 -0.00744 -0.12 -1.9009 -0.7407 3122074 ChemDiv3_013438 COc1ccc(CNC(=O)C2CN(C3CCCC3)C(=O)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C19 compound treatment 0.249 0.0288 0.41 0.238 -0.00244 -0.04 0.2622 0.6337 3122075 ChemDiv3_013439 COc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(cc23)S(=O)(=O)N4CCCCC4C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C20 compound treatment 0.237 0.0168 0.24 0.259 0.0186 0.31 0.39 0.9917 3036991 ChemDiv3_013440 CCC(C)NC(=O)CN1C(=O)C(CC)Sc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C21 compound treatment 0.243 0.0228 0.33 0.281 0.0406 0.68 0.7118 0.9431 3122076 ChemDiv3_013441 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)N2CCN(Cc3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C22 compound treatment 0.041 -0.179 -2.56 0.13 -0.11 -1.85 -3.1233 -0.9873 3037682 ChemDiv3_013442 CCc1ccc(NC(=O)N(Cc2ccco2)C(C)c3cccs3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C23 mock treatment 0.228 0.00778 0.11 0.211 -0.0294 -0.49 -0.2707 -0.5344 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 C24 mock treatment 0.214 -0.00622 -0.09 0.246 0.00556 0.09 0.0031 0.0242 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D01 compound treatment 0.264 0.0438 0.63 0.224 -0.0164 -0.28 0.2477 0.362 3122077 ChemDiv3_013443 CC(C)NC(=O)CCn1nc(ccc1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D02 compound treatment 0.217 -0.00322 -0.05 0.227 -0.0134 -0.23 -0.192 -0.8342 3037687 ChemDiv3_013444 Cc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(Br)cc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D03 compound treatment 0.284 0.0638 0.91 0.318 0.0776 1.3 1.5656 0.9849 3122078 ChemDiv3_013445 Clc1ccc(cc1)c2ccc(=O)n(CCC(=O)NCc3cccnc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D04 compound treatment 0.235 0.0148 0.21 0.227 -0.0134 -0.23 -0.01 -0.0323 3037691 ChemDiv3_013446 COCCN(C(C)c1ccccn1)C(=S)Nc2cccc(Cl)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D05 compound treatment 0.273 0.0528 0.75 0.264 0.0236 0.4 0.8135 0.9545 3122079 ChemDiv3_013447 CC1CCN(CCCNC(=O)C2CN(CCc3ccccc3)C(=O)C2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D06 compound treatment 0.257 0.0368 0.53 0.256 0.0156 0.26 0.5567 0.9478 3037758 ChemDiv3_013448 CC(N(C1CCCCC1)C(=S)Nc2cccc(Cl)c2C)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D07 compound treatment 0.196 -0.0242 -0.35 0.302 0.0616 1.03 0.4857 0.4457 3122080 ChemDiv3_013449 CCc1ccc(Sc2cc(C(=O)NCC3CCCO3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D08 compound treatment 0.269 0.0488 0.7 0.302 0.0616 1.03 1.224 0.9817 3037763 ChemDiv3_013450 Cc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D09 compound treatment 0.258 0.0378 0.54 0.246 0.00556 0.09 0.4481 0.8172 3122081 ChemDiv3_013451 CC1CCCC(NC(=O)c2ccc(N3CCCCC3)c(NS(=O)(=O)c4ccc(C)cc4)c2)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D10 compound treatment 0.255 0.0348 0.5 0.263 0.0226 0.38 0.6196 0.9909 3037767 ChemDiv3_013452 COc1ccc(cc1)N2CCC(CNC(=O)Nc3ccccc3)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D11 compound treatment 0.257 0.0368 0.53 0.311 0.0706 1.18 1.2095 0.9333 3122082 ChemDiv3_013453 CC1CCC(CC1)NC(=O)c2ccc(c(NC(=O)C)c2)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D12 compound treatment 0.239 0.0188 0.27 0.263 0.0226 0.38 0.4577 0.9859 3122083 ChemDiv3_013454 COCCN(C1CCN(CC1)C(=O)C)C(=O)Nc2ccc(OC)cc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D13 compound treatment 0.283 0.0628 0.9 0.299 0.0586 0.98 1.33 0.999 3037774 ChemDiv3_013455 CC(C)CCN1CC(CC1=O)C(=O)NCc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D14 compound treatment 0.266 0.0458 0.65 0.306 0.0656 1.1 1.2411 0.9693 3036687 ChemDiv3_013456 CN(CCC#N)C(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D15 compound treatment 0.253 0.0328 0.47 0.313 0.0726 1.22 1.1927 0.9139 3122084 ChemDiv3_013457 Cc1nnc(Sc2cc(C(=O)NCc3ccccn3)c4ccccc4n2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D16 compound treatment 0.253 0.0328 0.47 0.272 0.0316 0.53 0.7061 0.9981 3036693 ChemDiv3_013458 O=C(NC1CCCC1)c2ccc(/C=C\3/Sc4ccccc4NC3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D17 compound treatment 0.231 0.0108 0.15 0.313 0.0726 1.22 0.9702 0.7903 3122085 ChemDiv3_013459 CC1CC(C)CN(CCCNC(=O)c2cc(Sc3nnc(C)s3)nc4ccccc24)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D18 compound treatment 0.245 0.0248 0.35 0.288 0.0476 0.8 0.8151 0.9332 3036698 ChemDiv3_013460 CN(C(=O)CN1N=C(CCC1=O)c2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D19 compound treatment 0.247 0.0268 0.38 0.323 0.0826 1.39 1.2507 0.87 3122264 ChemDiv3_013461 COC(CNC(=O)c1ccc2n(cnc2c1)C3CCCCCC3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D20 compound treatment 0.261 0.0408 0.58 0.251 0.0106 0.18 0.5378 0.8822 3122265 ChemDiv3_013462 CC1CCCCC1NC(=O)c2ccc(/C=C\3/Sc4ccccc4NC3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D21 compound treatment 0.251 0.0308 0.44 0.293 0.0526 0.88 0.9351 0.9484 3036703 ChemDiv3_013463 CCOc1ccccc1NC(=S)NCc2cccn2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D22 compound treatment 0.252 0.0318 0.45 0.266 0.0256 0.43 0.6248 0.9996 3122266 ChemDiv3_013464 CCc1ccc(NC(=O)Cn2nc(ccc2=O)c3ccc(OC)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D23 mock treatment 0.216 -0.00422 -0.06 0.25 0.00956 0.16 0.0708 0.413 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 D24 mock treatment 0.214 -0.00622 -0.09 0.238 -0.00244 -0.04 -0.0918 -0.9379 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E01 compound treatment 0.239 0.0188 0.27 0.234 -0.00644 -0.11 0.1136 0.3922 3036776 ChemDiv3_013465 CCCN(CCC)C(=O)CSc1ncccc1C(=O)Oc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E02 compound treatment 0.228 0.00778 0.11 0.268 0.0276 0.46 0.4058 0.8529 3036779 ChemDiv3_013466 CC(C)N(C(C)c1ccccn1)C(=S)Nc2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E03 compound treatment 0.208 -0.0122 -0.17 0.229 -0.0114 -0.19 -0.2593 -0.9989 3122267 ChemDiv3_013467 CC(=O)Nc1cc(ccc1Sc2ccc(C)cc2)C(=O)NCCc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E04 compound treatment 0.209 -0.0112 -0.16 0.221 -0.0194 -0.33 -0.3442 -0.9466 3122268 ChemDiv3_013468 CCC1Oc2ccc(C)cc2N(CC(=O)NCCCN3CCN(CC3)c4ccccc4F)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E05 compound treatment 0.254 0.0338 0.48 0.289 0.0486 0.82 0.918 0.9688 3036783 ChemDiv3_013469 CC1CC(C)CN(C1)C(=O)c2ccc(Sc3ccc(Cl)cc3)c(NC(=O)C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E06 compound treatment 0.233 0.0128 0.18 0.261 0.0206 0.35 0.3733 0.9559 3122269 ChemDiv3_013470 O=C(Cn1nc(ccc1=O)c2ccccc2)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E07 compound treatment 0.271 0.0508 0.73 0.288 0.0476 0.8 1.0781 0.9989 3122270 ChemDiv3_013471 CCOC(=O)c1cccnc1SCC(=O)Nc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E08 compound treatment 0.252 0.0318 0.45 0.276 0.0356 0.6 0.7435 0.991 3036789 ChemDiv3_013472 CCS(=O)(=O)N1CCC(CC1)C(=O)NC2CCCCC2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E09 compound treatment 0.25 0.0298 0.43 0.283 0.0426 0.71 0.8063 0.9695 3122271 ChemDiv3_013473 COc1ccc(CCNC(=O)CCCc2cn(C)c3ccccc23)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E10 compound treatment 0.221 7.81E-4 0.01 0.244 0.00356 0.06 0.0502 0.825 3036860 ChemDiv3_013474 Cc1ccc(CNC(=O)CCSCc2ccc(C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E11 compound treatment 0.231 0.0108 0.15 0.224 -0.0164 -0.28 -0.086 -0.2722 3036863 ChemDiv3_013475 Sc1ncccc1C(=O)n2ccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E12 compound treatment 0.281 0.0608 0.87 0.24 -4.38E-4 -0.01 0.6096 0.7011 3036865 ChemDiv3_013476 CS(=O)(=O)N1CCCC(C1)C(=O)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E13 compound treatment 0.253 0.0328 0.47 0.291 0.0506 0.85 0.9316 0.9609 3122272 ChemDiv3_013477 CCOc1ccc(NC(=O)N(CCCN2CCOCC2)Cc3cccnc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E14 compound treatment 0.25 0.0298 0.43 0.272 0.0316 0.53 0.6758 0.9942 3036868 ChemDiv3_013478 C=CCNC(=O)CN1N=C(CCC1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E15 compound treatment 0.231 0.0108 0.15 0.304 0.0636 1.07 0.8634 0.801 3122273 ChemDiv3_013479 CCc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)N3CCCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E16 compound treatment 0.259 0.0388 0.55 0.29 0.0496 0.83 0.9805 0.9806 3122274 ChemDiv3_013480 CC(C)CN(CC(C)C)S(=O)(=O)N1CCC(CC1)C(=O)N2CCc3ccccc3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E17 compound treatment 0.242 0.0218 0.31 0.293 0.0526 0.88 0.8441 0.9022 3036873 ChemDiv3_013481 CC1CCN(CCCNC(=O)c2ccc3n(cnc3c2)C4CCCC4)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E18 compound treatment 0.258 0.0378 0.54 0.273 0.0326 0.55 0.7686 1.0 3122275 ChemDiv3_013482 Fc1ccc(CSCC(=O)NC2CCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E19 compound treatment 0.257 0.0368 0.53 0.287 0.0466 0.78 0.9246 0.9815 3036925 ChemDiv3_013483 COCCN(C1CCN(CC1)C(C)C)C(=S)Nc2ccc(cc2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E20 compound treatment 0.23 0.00978 0.14 0.282 0.0416 0.7 0.5922 0.8323 3122276 ChemDiv3_013484 CC1CCCCN1CCNC(=O)Cn2nc(ccc2=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E21 compound treatment 0.223 0.00278 0.04 0.269 0.0286 0.48 0.3671 0.7632 3036929 ChemDiv3_013485 CCOC(=O)N1CCC(CC1)N(CCOC)C(=S)Nc2ccc(C)cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E22 compound treatment 0.201 -0.0192 -0.27 0.257 0.0166 0.28 0.0022 0.0056 3122277 ChemDiv3_013486 CC1CCN(CC1)C(=O)Cn2nc(ccc2=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E23 mock treatment 0.2 -0.0202 -0.29 0.208 -0.0324 -0.54 -0.5895 -0.9562 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 E24 mock treatment 0.209 -0.0112 -0.16 0.247 0.00656 0.11 -0.0356 -0.1828 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F01 compound treatment 0.236 0.0158 0.23 0.261 0.0206 0.35 0.4037 0.9788 3122278 ChemDiv3_013487 CC1CCCN(CCCNC(=O)CCn2nc(ccc2=O)c3ccccc3)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F02 compound treatment 0.243 0.0228 0.33 0.304 0.0636 1.07 0.9848 0.8828 3036935 ChemDiv3_013488 COC(CNC(=O)c1cc(=O)[nH]c2ccc(Br)cc12)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F03 compound treatment 0.24 0.0198 0.28 0.282 0.0416 0.7 0.6933 0.921 3122279 ChemDiv3_013489 Clc1ccc(cc1)c2ccc(=O)n(CCC(=O)N3CCC4(CC3)OCCO4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F04 compound treatment 0.234 0.0138 0.2 0.28 0.0396 0.66 0.6089 0.8791 3036938 ChemDiv3_013490 COc1cc(Cl)c(C)cc1NC(=S)N(CCN(C)C)C(C)c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F05 compound treatment 0.272 0.0518 0.74 0.333 0.0926 1.55 1.6223 0.9426 3122280 ChemDiv3_013491 O=C(NC1CCCC1)C2CN(CCc3ccccc3)C(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F06 compound treatment 0.286 0.0658 0.94 0.325 0.0846 1.42 1.6689 0.9801 3039062 ChemDiv3_013492 O=C(NC1CC1)/C=C/2\Sc3ccccc3NC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F07 compound treatment 0.25 0.0298 0.43 0.298 0.0576 0.97 0.9844 0.9323 3039063 ChemDiv3_013493 CCc1ccc(Sc2cc(C(=O)NCc3cccnc3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F08 compound treatment 0.239 0.0188 0.27 0.258 0.0176 0.29 0.3984 0.9989 3039064 ChemDiv3_013494 COC(CNC(=O)c1cc(nc2ccc(cc12)S(=O)(=O)N3CCC(C)CC3)c4ccccn4)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F09 compound treatment 0.252 0.0318 0.45 0.28 0.0396 0.66 0.791 0.9829 3039065 ChemDiv3_013495 CNC(=O)C1CN(C2CCCCCC2)C(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F10 compound treatment 0.25 0.0298 0.43 0.315 0.0746 1.25 1.1861 0.8972 3039066 ChemDiv3_013496 Fc1ccc(cc1)N2CCN(CC2)C(=O)CN3C(=O)/C(=C/c4ccccc4F)/Sc5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F11 compound treatment 0.24 0.0198 0.28 0.313 0.0726 1.22 1.0613 0.8488 3039067 ChemDiv3_013497 CC1CCN(CCCNC(=O)c2ccc(c(NC(=O)C)c2)S(=O)(=O)c3ccc(Cl)cc3)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F12 compound treatment 0.315 0.0948 1.36 0.307 0.0666 1.12 1.7486 0.9954 3122281 ChemDiv3_013498 CC(C)CCN(C(C)c1ccncc1)C(=S)Nc2ccccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F13 compound treatment 0.275 0.0548 0.78 0.316 0.0756 1.27 1.4509 0.9732 3122282 ChemDiv3_013499 CC(C)NC(=O)C1CCC(=O)N1Cc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F14 compound treatment 0.293 0.0728 1.04 0.325 0.0846 1.42 1.7397 0.9884 3039068 ChemDiv3_013500 CCC(C)NC(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F15 compound treatment 0.277 0.0568 0.81 0.289 0.0486 0.82 1.1506 1.0 3122283 ChemDiv3_013501 Cc1nnc(Sc2cc(C(=O)NCCc3ccccc3)c4ccccc4n2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F16 compound treatment 0.263 0.0428 0.61 0.267 0.0266 0.45 0.7479 0.9879 3039069 ChemDiv3_013502 CNC(=O)c1ccc(/C=C\2/Sc3ccccc3NC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F17 compound treatment 0.299 0.0788 1.13 0.325 0.0846 1.42 1.8004 0.9935 3122284 ChemDiv3_013503 Fc1ccc(CN2C(CCC2=O)C(=O)NCc3ccccc3Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F18 compound treatment 0.241 0.0208 0.3 0.248 0.00756 0.13 0.2999 0.928 3122285 ChemDiv3_013504 Clc1ccc(CNC(=O)C2CCC(CNS(=O)(=O)c3ccc(Cl)cc3)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F19 compound treatment 0.233 0.0128 0.18 0.25 0.00956 0.16 0.2428 0.9979 3039070 ChemDiv3_013505 Clc1ccc(CCNC(=O)c2cc(=O)[nH]c3ccc(Br)cc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F20 compound treatment 0.25 0.0298 0.43 0.239 -0.00144 -0.02 0.2842 0.666 3122286 ChemDiv3_013506 Clc1cccc(NC(=S)N2CCCN(Cc3ccccc3Cl)C2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F21 compound treatment 0.203 -0.0172 -0.25 0.218 -0.0224 -0.38 -0.4404 -0.9788 3039071 ChemDiv3_013507 CCc1cccc(NC(=S)N2CCC(C2)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F22 compound treatment 0.216 -0.00422 -0.06 0.282 0.0416 0.7 0.4506 0.6435 3122287 ChemDiv3_013508 COc1ccc(CCNC(=O)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F23 mock treatment 0.239 0.0188 0.27 0.3 0.0596 1.0 0.8969 0.8664 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 F24 mock treatment 0.205 -0.0152 -0.22 0.272 0.0316 0.53 0.2207 0.3853 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G01 compound treatment 0.256 0.0358 0.51 0.287 0.0466 0.78 0.9145 0.9789 3122288 ChemDiv3_013509 CC(C)N1C(CCC1=O)C(=O)NCCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G02 compound treatment 0.211 -0.00922 -0.13 0.267 0.0266 0.45 0.222 0.4775 3039072 ChemDiv3_013510 CS(=O)(=O)N1CCC(CC1)C(=O)NC2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G03 compound treatment 0.216 -0.00422 -0.06 0.232 -0.00844 -0.14 -0.1428 -0.9277 3122289 ChemDiv3_013511 CCc1ccc(CNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G04 compound treatment 0.277 0.0568 0.81 0.248 0.00756 0.13 0.6641 0.8078 3039073 ChemDiv3_013512 CC(C)CCN1CC(CC1=O)C(=O)NC2CCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G05 compound treatment 0.225 0.00478 0.07 0.272 0.0316 0.53 0.4229 0.7918 3122290 ChemDiv3_013513 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)N3CCc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G06 compound treatment 0.269 0.0488 0.7 0.265 0.0246 0.41 0.7849 0.9685 3039074 ChemDiv3_013514 O=C(Cn1nc(ccc1=O)c2ccccc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G07 compound treatment 0.306 0.0858 1.23 0.296 0.0556 0.93 1.527 0.9908 3122291 ChemDiv3_013515 CSc1cccc(NC(=O)CSc2ncccc2C(=O)OC(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G08 compound treatment 0.219 -0.00122 -0.02 0.321 0.0806 1.35 0.9438 0.6979 3039075 ChemDiv3_013516 CCC(C)NC(=O)C1CCN(CC1)S(=O)(=O)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G09 compound treatment 0.21 -0.0102 -0.15 0.295 0.0546 0.92 0.5442 0.5868 3122480 ChemDiv3_013517 CC(C)N(C1CCN(CC1)C(C)C)C(=S)Nc2cc(Cl)ccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G10 compound treatment 0.246 0.0258 0.37 0.235 -0.00544 -0.09 0.1962 0.5165 3122481 ChemDiv3_013518 COc1ccccc1NC(=S)N(C(C)c2ccco2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G11 compound treatment 0.201 -0.0192 -0.27 0.282 0.0416 0.7 0.2989 0.3986 3039076 ChemDiv3_013519 CC1CC(C)CN(C1)C(=O)c2cc(nc3ccc(cc23)S(=O)(=O)N4CCOCC4)c5ccccn5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G12 compound treatment 0.294 0.0738 1.06 0.289 0.0486 0.82 1.3226 0.9919 3122482 ChemDiv3_013520 CC1CC(C)CN(C1)S(=O)(=O)N2CCCC(C2)C(=O)NCCN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G13 compound treatment 0.238 0.0178 0.25 0.29 0.0496 0.83 0.7681 0.883 3122483 ChemDiv3_013521 CCc1ccc(NC(=O)N(Cc2ccco2)Cc3cccnc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G14 compound treatment 0.297 0.0768 1.1 0.303 0.0626 1.05 1.5191 0.9997 3039077 ChemDiv3_013522 CC1CCCCC1NC(=O)CN2N=C(CCC2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G15 compound treatment 0.263 0.0428 0.61 0.258 0.0176 0.29 0.6411 0.9439 3122484 ChemDiv3_013523 COc1ccc(CCN(Cc2ccccn2)S(=O)(=O)c3ccc(cc3)C(C)(C)C)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G16 compound treatment 0.239 0.0188 0.27 0.269 0.0286 0.48 0.5289 0.9625 3039078 ChemDiv3_013524 COc1cccc(CNC(=O)CCS(=O)(=O)Cc2ccc(C)cc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G17 compound treatment 0.295 0.0748 1.07 0.299 0.0586 0.98 1.4514 0.9991 3122485 ChemDiv3_013525 CCOC(=O)N1CCN(CC1)C(=O)c2ccc3n(cnc3c2)C4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G18 compound treatment 0.283 0.0628 0.9 0.265 0.0246 0.41 0.9265 0.9376 3039079 ChemDiv3_013526 Cc1ccc(CSCC(=O)N2CCN(CC2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G19 compound treatment 0.241 0.0208 0.3 0.207 -0.0334 -0.56 -0.1867 -0.2939 3122486 ChemDiv3_013527 CCOC(=O)N1CCN(CC1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G20 compound treatment 0.253 0.0328 0.47 0.269 0.0286 0.48 0.6705 0.9999 3122487 ChemDiv3_013528 Cc1ccc(CSCc2ccc(o2)C(=O)NCCc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G21 compound treatment 0.234 0.0138 0.2 0.255 0.0146 0.24 0.3122 0.9943 3039080 ChemDiv3_013529 CCOc1ccc(CCNC(=O)C2CCN(CC2)S(=O)(=O)C)cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G22 compound treatment 0.241 0.0208 0.3 0.263 0.0226 0.38 0.478 0.9928 3122488 ChemDiv3_013530 Clc1ccc(cc1)c2ccc(=O)n(CC(=O)NCc3ccco3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G23 mock treatment 0.203 -0.0172 -0.25 0.232 -0.00844 -0.14 -0.2743 -0.9655 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 G24 mock treatment 0.213 -0.00722 -0.1 0.253 0.0126 0.21 0.0761 0.3241 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H01 compound treatment 0.264 0.0438 0.63 0.274 0.0336 0.56 0.8411 0.9986 3039081 ChemDiv3_013531 O=C(CCn1nc(ccc1=O)c2ccccc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H02 compound treatment 0.243 0.0228 0.33 0.302 0.0616 1.03 0.961 0.887 3122489 ChemDiv3_013532 CC(NC(=O)c1cc(=O)[nH]c2ccc(Br)cc12)c3ccc4OCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H03 compound treatment 0.237 0.0168 0.24 0.302 0.0616 1.03 0.9004 0.8488 3039082 ChemDiv3_013533 CCOC(=O)N1CCN(CC1)C(=O)CCn2nc(ccc2=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H04 compound treatment 0.272 0.0518 0.74 0.252 0.0116 0.19 0.661 0.8632 3122490 ChemDiv3_013534 COc1ccc(cc1)N2CCC(CNS(=O)(=O)c3cccc(c3)C(F)(F)F)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H05 compound treatment 0.211 -0.00922 -0.13 0.316 0.0756 1.27 0.8035 0.6302 3122491 ChemDiv3_013535 CC1CCCC(C)N1CCNC(=O)CCn2nc(ccc2=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H06 compound treatment 0.25 0.0298 0.43 0.295 0.0546 0.92 0.9488 0.9394 3039083 ChemDiv3_013536 O=C(/C=C/1\Sc2ccccc2NC1=O)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H07 compound treatment 0.188 -0.0322 -0.46 0.271 0.0306 0.51 0.0369 0.0534 3122492 ChemDiv3_013537 CCOc1ccc(Sc2cc(C(=O)N3CCCC3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H08 compound treatment 0.254 0.0338 0.48 0.288 0.0476 0.8 0.9061 0.9711 3122493 ChemDiv3_013538 CC1CCN(CC1)S(=O)(=O)c2ccc3nc(cc(C(=O)NC4CCCC4)c3c2)c5ccccn5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H09 compound treatment 0.263 0.0428 0.61 0.323 0.0826 1.39 1.4126 0.9325 3039084 ChemDiv3_013539 CCS(=O)(=O)N1CCCC(C1)C(=O)NCc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H10 compound treatment 0.25 0.0298 0.43 0.312 0.0716 1.2 1.1505 0.9028 3122494 ChemDiv3_013540 NC(=O)C1CCN(CC1)C(=O)CN2C(=O)/C(=C/c3ccccc3F)/Sc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H11 compound treatment 0.255 0.0348 0.5 0.329 0.0886 1.49 1.4029 0.895 3039085 ChemDiv3_013541 O=C(NCCCN1CCCC1=O)c2ccc3n(cnc3c2)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H12 compound treatment 0.309 0.0888 1.27 0.306 0.0656 1.1 1.6761 0.9975 3122495 ChemDiv3_013542 COc1ccc(cc1)C2=NN(CCC(=O)NC3CC3)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H13 compound treatment 0.183 -0.0372 -0.53 0.211 -0.0294 -0.49 -0.7258 -0.9993 3039086 ChemDiv3_013543 CCc1cccc(NC(=S)N(CCC(C)C)C(C)c2cccs2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H14 compound treatment 0.319 0.0988 1.41 0.311 0.0706 1.18 1.8365 0.9961 3122496 ChemDiv3_013544 O=C(C1CCC(CNS(=O)(=O)c2ccccc2)CC1)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H15 compound treatment 0.233 0.0128 0.18 0.291 0.0506 0.85 0.7294 0.8402 3122497 ChemDiv3_013545 Cc1nnc(Sc2cc(C(=O)NC3CC3)c4ccccc4n2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H16 compound treatment 0.167 -0.0532 -0.76 0.192 -0.0484 -0.81 -1.1131 -0.9995 3039087 ChemDiv3_013546 CCc1cccc(NC(=S)N(C)Cc2cn(C)c3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H17 compound treatment 0.286 0.0658 0.94 0.299 0.0586 0.98 1.3604 0.9998 3122498 ChemDiv3_013547 CCCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(C)cc2)C(=O)NC3CCCCC3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H18 compound treatment 0.222 0.00178 0.03 0.247 0.00656 0.11 0.0959 0.8483 3039088 ChemDiv3_013548 CSc1cccc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H19 compound treatment 0.22 -2.19E-4 0.0 0.212 -0.0284 -0.48 -0.3397 -0.7117 3122499 ChemDiv3_013549 Cc1cccc(CCNC(=O)c2cc(O)nc3ccc(Br)cc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H20 compound treatment 0.213 -0.00722 -0.1 0.253 0.0126 0.21 0.0761 0.3241 3122500 ChemDiv3_013550 CC(C)c1ccc(NC(=O)CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)N5CCCC5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H21 compound treatment 0.236 0.0158 0.23 0.264 0.0236 0.4 0.4393 0.9646 3039089 ChemDiv3_013551 CCC1=Nc2cc(ccc2Sc3ccc(C)cc13)C(=O)NCCN4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H22 compound treatment 0.209 -0.0112 -0.16 0.183 -0.0574 -0.96 -0.7951 -0.8136 3122501 ChemDiv3_013552 O=C(NCCC1=CCCCC1)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H23 mock treatment 0.225 0.00478 0.07 0.229 -0.0114 -0.19 -0.0874 -0.4288 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 H24 mock treatment 0.207 -0.0132 -0.19 0.224 -0.0164 -0.28 -0.3288 -0.983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I01 compound treatment 0.269 0.0488 0.7 0.283 0.0426 0.71 0.9985 0.9999 3039090 ChemDiv3_013553 CN(C)CCNC(=O)c1ccc(Sc2ccc(Cl)cc2)c(NC(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I02 compound treatment 0.243 0.0228 0.33 0.281 0.0406 0.68 0.7118 0.9431 3122502 ChemDiv3_013554 CS(=O)(=O)N1CCC(CC1)C(=O)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I03 compound treatment 0.279 0.0588 0.84 0.306 0.0656 1.1 1.3726 0.9912 3122503 ChemDiv3_013555 CCC1Oc2ccc(Cl)cc2N(CC(=O)NCCc3ccccc3)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I04 compound treatment 0.277 0.0568 0.81 0.276 0.0356 0.6 0.9964 0.9885 3039091 ChemDiv3_013556 CN(C)C(=O)N1CCCC(C1)C(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I05 compound treatment 0.26 0.0398 0.57 0.264 0.0236 0.4 0.682 0.9842 3122504 ChemDiv3_013557 CCCCN(C)C(=O)c1ccc(Sc2ccc(Cl)cc2)c(NC(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I06 compound treatment 0.306 0.0858 1.23 0.299 0.0586 0.98 1.5626 0.994 3039092 ChemDiv3_013558 COc1ccc(CNC(=O)Cn2nc(ccc2=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I07 compound treatment 0.264 0.0438 0.63 0.299 0.0586 0.98 1.1378 0.9763 3122505 ChemDiv3_013559 CC(C)OC(=O)c1cccnc1SCc2cc(=O)n3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I08 compound treatment 0.224 0.00378 0.05 0.301 0.0606 1.02 0.757 0.7437 3122506 ChemDiv3_013560 CCS(=O)(=O)N1CCC(CC1)C(=O)NCc2ccc(F)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I09 compound treatment 0.224 0.00378 0.05 0.207 -0.0334 -0.56 -0.3586 -0.636 3039093 ChemDiv3_013561 COc1ccc(NC(=S)N(C(C)C)C2CCN(CC2)C(C)C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I10 compound treatment 0.18 -0.0402 -0.58 0.203 -0.0374 -0.63 -0.8511 -0.999 3122688 ChemDiv3_013562 CC(N(C1CCCCC1)C(=O)Nc2ccccc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I11 compound treatment 0.243 0.0228 0.33 0.255 0.0146 0.24 0.4032 0.99 3039094 ChemDiv3_013563 O=C(CNC(=O)c1cccs1)NCc2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I12 compound treatment 0.275 0.0548 0.78 0.285 0.0446 0.75 1.0829 0.9997 3122689 ChemDiv3_013564 COc1ccc(OC)c(CNC(=O)C2CCCN(C2)S(=O)(=O)N3CC(C)CC(C)C3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I13 compound treatment 0.242 0.0218 0.31 0.274 0.0336 0.56 0.6186 0.961 3122690 ChemDiv3_013565 COc1ccc(NC(=O)N(Cc2ccc(C)cc2)Cc3ccccn3)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I14 compound treatment 0.245 0.0248 0.35 0.288 0.0476 0.8 0.8151 0.9332 3039095 ChemDiv3_013566 O=C(CN1C(=O)COc2ccccc12)NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I15 compound treatment 0.253 0.0328 0.47 0.22 -0.0204 -0.34 0.089 0.1532 3122691 ChemDiv3_013567 O=C(NCCC1=CCCCC1)c2ccc3n(cnc3c2)C4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I16 compound treatment 0.184 -0.0362 -0.52 0.242 0.00156 0.03 -0.3478 -0.6705 3039326 ChemDiv3_013568 CCC(N1C(=O)CSc2ccc(cc12)C(C)(C)C)C(=O)NCc3ccc(OC)cc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I17 compound treatment 0.289 0.0688 0.98 0.265 0.0246 0.41 0.9872 0.9254 3039327 ChemDiv3_013569 O=C(CCN1C(=O)COc2ccccc12)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I18 compound treatment 0.293 0.0728 1.04 0.292 0.0516 0.87 1.3481 0.9958 3039329 ChemDiv3_013570 COc1ccccc1CN2CC(CC2=O)C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I19 compound treatment 0.286 0.0658 0.94 0.276 0.0356 0.6 1.0874 0.9759 3039330 ChemDiv3_013571 CCOc1ccccc1CN2C(C(=O)NCCCN3C(C)CCCC3C)c4ccccc4C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I20 compound treatment 0.282 0.0618 0.88 0.259 0.0186 0.31 0.8452 0.902 3039332 ChemDiv3_013572 CCc1ccc(CNC(=O)c2ccc(CSCc3ccc(C)cc3)o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I21 compound treatment 0.222 0.00178 0.03 0.276 0.0356 0.6 0.4401 0.7366 3122692 ChemDiv3_013573 CS(=O)(=O)N1CCC(CC1)C(=O)NCCN2CCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I22 compound treatment 0.208 -0.0122 -0.17 0.262 0.0216 0.36 0.1323 0.3292 3039333 ChemDiv3_013574 CC1CCCCC1NC(=O)Cn2nc(ccc2=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I23 mock treatment 0.208 -0.0122 -0.17 0.217 -0.0234 -0.39 -0.4017 -0.9333 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 I24 mock treatment 0.205 -0.0152 -0.22 0.243 0.00256 0.04 -0.1235 -0.5566 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J01 compound treatment 0.235 0.0148 0.21 0.182 -0.0584 -0.98 -0.544 -0.5422 3122693 ChemDiv3_013575 CC1CCCC(NC(=O)c2ccc(CSCc3cccc(C)c3)o2)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J02 compound treatment 0.283 0.0628 0.9 0.294 0.0536 0.9 1.2707 1.0 3122694 ChemDiv3_013576 Brc1ccc2[nH]c(=O)cc(C(=O)NCC3CCCO3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J03 compound treatment 0.248 0.0278 0.4 0.31 0.0696 1.17 1.1066 0.8972 3039336 ChemDiv3_013577 Clc1cccc(Sc2cc(C(=O)NCCN3CCCC3)c4ccccc4n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J04 compound treatment 0.256 0.0358 0.51 0.244 0.00356 0.06 0.4042 0.7844 3122695 ChemDiv3_013578 COc1ccc(cc1)N2CCC(CNS(=O)(=O)c3cccc(Cl)c3)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J05 compound treatment 0.241 0.0208 0.3 0.271 0.0306 0.51 0.5729 0.9663 3122696 ChemDiv3_013579 Cc1ccc(cc1)c2ccc(=O)n(CCC(=O)NCCN3CCN(CC3)c4cccc(Cl)c4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J06 compound treatment 0.263 0.0428 0.61 0.315 0.0746 1.25 1.3176 0.9458 3039338 ChemDiv3_013580 CC1N=C(c2ccccc2)c3ccccc3N(CCCOc4ccc(F)cc4)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J07 compound treatment 0.253 0.0328 0.47 0.294 0.0536 0.9 0.9672 0.954 3122697 ChemDiv3_013581 CC(C)NC(=O)C1CCC(=O)N1Cc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J08 compound treatment 0.245 0.0248 0.35 0.33 0.0896 1.5 1.3136 0.8505 3039340 ChemDiv3_013582 O=C(NC1CCCC1)C2CCCN(C2)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J09 compound treatment 0.257 0.0368 0.53 0.267 0.0266 0.45 0.6873 0.9966 3122698 ChemDiv3_013583 CCS(=O)(=O)N1CCCC(C1)C(=O)NCCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J10 compound treatment 0.264 0.0438 0.63 0.335 0.0946 1.59 1.5651 0.9173 3122699 ChemDiv3_013584 COC(CNC(=O)c1ccc2Sc3ccccc3C(=O)N(CC=C)c2c1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J11 compound treatment 0.195 -0.0252 -0.36 0.25 0.00956 0.16 -0.1416 -0.3586 3039343 ChemDiv3_013585 CSc1ccccc1Sc2cc(C(=O)NCc3ccco3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J12 compound treatment 0.247 0.0268 0.38 0.28 0.0396 0.66 0.7404 0.9658 3039473 ChemDiv3_013586 COC(=O)c1ccc2SCC(=O)N(CC#N)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J13 compound treatment 0.229 0.00878 0.13 0.271 0.0306 0.51 0.4515 0.855 3039389 ChemDiv3_013587 CCc1cccc(NC(=S)N(CCOC)C(C)c2cccs2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J14 compound treatment 0.244 0.0238 0.34 0.316 0.0756 1.27 1.1373 0.8661 3039391 ChemDiv3_013588 COC(CNC(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J15 compound treatment 0.298 0.0778 1.11 0.26 0.0196 0.33 1.0189 0.8783 3039392 ChemDiv3_013589 Clc1ccccc1NC(=S)Nc2ccc(CN3CCOCC3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J16 compound treatment 0.237 0.0168 0.24 0.224 -0.0164 -0.28 -0.0254 -0.0693 3039394 ChemDiv3_013590 CC(C)c1ccc(NC(=O)CN2N=C(CCC2=O)c3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J17 compound treatment 0.285 0.0648 0.93 0.246 0.00556 0.09 0.7212 0.7744 3039396 ChemDiv3_013591 CCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(C)cc2)C(=O)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J18 compound treatment 0.225 0.00478 0.07 0.277 0.0366 0.61 0.4823 0.7811 3039397 ChemDiv3_013592 Cc1ccc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J19 compound treatment 0.241 0.0208 0.3 0.29 0.0496 0.83 0.7984 0.9038 3122700 ChemDiv3_013593 Cc1ccc(CN2C(=O)/C(=C/C(=O)NCCc3ccccc3)/Sc4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J20 compound treatment 0.265 0.0448 0.64 0.257 0.0166 0.28 0.6495 0.9302 3122701 ChemDiv3_013594 CCCCN1CCCc2cc(CN(Cc3ccco3)C(=S)Nc4ccc(Cl)cc4OC)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J21 compound treatment 0.294 0.0738 1.06 0.295 0.0546 0.92 1.3938 0.9975 3039400 ChemDiv3_013595 Cc1ccc(cc1)C2=NN(CCC(=O)N3CCC(CC3)C(=O)N)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J22 compound treatment 0.232 0.0118 0.17 0.288 0.0476 0.8 0.6836 0.8379 3039401 ChemDiv3_013596 CCCCN(C1CCN(CC1)C(=O)C)C(=S)Nc2cccc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J23 mock treatment 0.275 0.0548 0.78 0.283 0.0426 0.71 1.0592 0.9989 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 J24 mock treatment 0.23 0.00978 0.14 0.199 -0.0414 -0.7 -0.3929 -0.5538 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K01 compound treatment 0.234 0.0138 0.2 0.265 0.0246 0.41 0.4309 0.943 3122702 ChemDiv3_013597 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K02 compound treatment 0.256 0.0358 0.51 0.267 0.0266 0.45 0.6771 0.9976 3122703 ChemDiv3_013598 COc1ccc(Br)cc1CNC(=O)C2CCN(CC2)C(=O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K03 compound treatment 0.274 0.0538 0.77 0.272 0.0316 0.53 0.9185 0.9834 3039404 ChemDiv3_013599 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K04 compound treatment 0.259 0.0388 0.55 0.288 0.0476 0.8 0.9567 0.9842 3122704 ChemDiv3_013600 CC(=O)N1CCC(CC1)N(C2CCCC2)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K05 compound treatment 0.286 0.0658 0.94 0.276 0.0356 0.6 1.0874 0.9759 3122705 ChemDiv3_013601 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)N3CCC(=CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K06 compound treatment 0.28 0.0598 0.86 0.29 0.0496 0.83 1.1929 0.9999 3039406 ChemDiv3_013602 O=C(Cn1nc(ccc1=O)c2ccccc2)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K07 compound treatment 0.264 0.0438 0.63 0.274 0.0336 0.56 0.8411 0.9986 3122706 ChemDiv3_013603 Clc1ccc(CCNC(=O)CCc2cn(Cc3ccccc3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K08 compound treatment 0.275 0.0548 0.78 0.277 0.0366 0.61 0.988 0.9927 3039407 ChemDiv3_013604 COc1ccc(CNC(=O)CN2N=C(CCC2=O)c3ccc(Cl)cc3)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K09 compound treatment 0.233 0.0128 0.18 0.249 0.00856 0.14 0.2309 0.9929 3122707 ChemDiv3_013605 CC(C)N1CCC(CC1)N(Cc2ccco2)C(=S)Nc3cccc(Cl)c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K10 compound treatment 0.261 0.0408 0.58 0.274 0.0336 0.56 0.8108 0.9998 3122708 ChemDiv3_013606 CCc1cccc(NC(=S)N(C(C)c2cccs2)C3CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K11 compound treatment 0.282 0.0618 0.88 0.299 0.0586 0.98 1.3199 0.9986 3039409 ChemDiv3_013607 CC1(C)CC(=O)c2cc(OCC(=O)N3CCN(Cc4ccccc4)CC3)ccc2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K12 compound treatment 0.281 0.0608 0.87 0.322 0.0816 1.37 1.5827 0.976 3122709 ChemDiv3_013608 CC1CC(C)CN(C1)S(=O)(=O)N2CCCC(C2)C(=O)NC3CCCC(C)C3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K13 compound treatment 0.234 0.0138 0.2 0.316 0.0756 1.27 1.0362 0.8073 3039411 ChemDiv3_013609 CC1(C)CC(=O)c2cc(OCC(=O)NC3CCCC3)ccc2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K14 compound treatment 0.194 -0.0262 -0.38 0.313 0.0726 1.22 0.596 0.4677 3122710 ChemDiv3_013610 CC1CCCC(NC(=O)CCSCc2ccc(C)cc2)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K15 compound treatment 0.239 0.0188 0.27 0.235 -0.00544 -0.09 0.1254 0.4421 3122711 ChemDiv3_013611 Clc1ccc(CCNC(=O)c2ccc3n(cnc3c2)C4CCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K16 compound treatment 0.28 0.0598 0.86 0.273 0.0326 0.55 0.9911 0.9766 3039414 ChemDiv3_013612 CCOC(=O)N1CCC(CC1)N(CCN(C)C)C(=S)Nc2ccc(C)c(F)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K17 compound treatment 0.275 0.0548 0.78 0.252 0.0116 0.19 0.6913 0.8564 3039474 ChemDiv3_013613 CN(Cc1ccccc1)C(=O)CCN2C(=O)COc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K18 compound treatment 0.272 0.0518 0.74 0.298 0.0576 0.97 1.2069 0.9914 3039475 ChemDiv3_013614 CCC1Sc2ccccc2N(CC(=O)NC3CC3)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K19 compound treatment 0.226 0.00578 0.08 0.286 0.0456 0.76 0.5992 0.779 3039476 ChemDiv3_013615 COc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K20 compound treatment 0.237 0.0168 0.24 0.194 -0.0464 -0.78 -0.3814 -0.4677 3039477 ChemDiv3_013616 Cc1ccc(CSCc2ccc(o2)C(=O)NC3CCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K21 compound treatment 0.218 -0.00222 -0.03 0.243 0.00256 0.04 0.008 0.1491 3039479 ChemDiv3_013617 Clc1ccc(SCCNC(=O)Nc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K22 compound treatment 0.254 0.0338 0.48 0.274 0.0336 0.56 0.74 0.9971 3039481 ChemDiv3_013618 CC1CCCCC1NC(=O)CCn2nc(ccc2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K23 mock treatment 0.224 0.00378 0.05 0.257 0.0166 0.28 0.2348 0.8291 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 K24 mock treatment 0.183 -0.0372 -0.53 0.185 -0.0554 -0.93 -1.0344 -0.9649 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L01 compound treatment 0.257 0.0368 0.53 0.217 -0.0234 -0.39 0.0939 0.1429 3122712 ChemDiv3_013619 Cc1ccccc1CS(=O)(=O)Cc2ccc(o2)C(=O)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L02 compound treatment 0.316 0.0958 1.37 0.287 0.0466 0.78 1.5214 0.9646 1108774 ChemDiv3_013620 COC(=O)C(C)C1Sc2ccccc2NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L03 compound treatment 0.272 0.0518 0.74 0.304 0.0636 1.07 1.2781 0.9841 3122713 ChemDiv3_013621 COc1ccc(CN2CC(CC2=O)C(=O)NCCN3CCN(CC3)c4ccccc4F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L04 compound treatment 0.284 0.0638 0.91 0.28 0.0396 0.66 1.1146 0.9878 3122714 ChemDiv3_013622 CN(Cc1ccccc1)C(=O)c2c[nH]c3ccc(cc3c2=O)S(=O)(=O)Nc4ccccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L05 compound treatment 0.274 0.0538 0.77 0.31 0.0696 1.17 1.3695 0.9795 3039484 ChemDiv3_013623 CC1CCCC(C)N1CCNC(=O)c2ccc3n(cnc3c2)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L06 compound treatment 0.259 0.0388 0.55 0.326 0.0856 1.44 1.4077 0.9144 3122888 ChemDiv3_013624 CC(N(CCN(C)C)C(=S)Nc1cc(F)cc(F)c1)c2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L07 compound treatment 0.302 0.0818 1.17 0.266 0.0256 0.43 1.1305 0.9074 3039485 ChemDiv3_013625 CCCCN1CC(CC1=O)C(=O)NCCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L08 compound treatment 0.306 0.0858 1.23 0.277 0.0366 0.61 1.3015 0.9487 3122889 ChemDiv3_013626 Cc1ccc(CCNC(=O)c2coc3nc4ccccc4nc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L09 compound treatment 0.223 0.00278 0.04 0.272 0.0316 0.53 0.4027 0.7581 3039487 ChemDiv3_013627 CCS(=O)(=O)N1CCCC(C1)C(=O)NC2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L10 compound treatment 0.251 0.0308 0.44 0.31 0.0696 1.17 1.1369 0.9111 3122890 ChemDiv3_013628 Fc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)NC3CCCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L11 compound treatment 0.257 0.0368 0.53 0.246 0.00556 0.09 0.438 0.8198 3122891 ChemDiv3_013629 CC(CNC(=O)Nc1ccccc1)CSc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L12 compound treatment 0.197 -0.0232 -0.33 0.219 -0.0214 -0.36 -0.4893 -0.9992 3039490 ChemDiv3_013630 CCc1cccc(NC(=S)N(Cc2c[nH]c3ccccc23)C4CCCC4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L13 compound treatment 0.295 0.0748 1.07 0.278 0.0376 0.63 1.2021 0.9682 3122892 ChemDiv3_013631 CC(C)N1CCC(CC1)N(CCN(C)C)C(=S)Nc2cc(C)cc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L14 compound treatment 0.263 0.0428 0.61 0.32 0.0796 1.34 1.377 0.9374 3122893 ChemDiv3_013632 O=C(NCc1cccs1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L15 compound treatment 0.043 -0.177 -2.53 0.049 -0.191 -3.21 -4.0644 -0.9931 3039493 ChemDiv3_013633 CC(CNC(=S)Nc1cccc(Cl)c1)CSc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L16 compound treatment 0.304 0.0838 1.2 0.272 0.0316 0.53 1.222 0.9326 3122894 ChemDiv3_013634 COc1ccc(NC(=S)N(Cc2cccn2Cc3ccc(C)cc3C)Cc4ccccc4)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L17 compound treatment 0.231 0.0108 0.15 0.253 0.0126 0.21 0.2581 0.9882 3039496 ChemDiv3_013635 COc1ccc(cc1)C2=NN(CC(=O)NCC3CCCO3)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L18 compound treatment 0.238 0.0178 0.25 0.292 0.0516 0.87 0.7918 0.8778 3122895 ChemDiv3_013636 COc1ccc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L19 compound treatment 0.243 0.0228 0.33 0.291 0.0506 0.85 0.8305 0.9136 3122896 ChemDiv3_013637 O=C(NC1CCCCC1)c2ccc3n(cnc3c2)C4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L20 compound treatment 0.265 0.0448 0.64 0.289 0.0486 0.82 1.0293 0.9929 3039498 ChemDiv3_013638 Fc1ccccc1CS(=O)(=O)Cc2ccc(o2)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L21 compound treatment 0.336 0.116 1.66 0.323 0.0826 1.39 2.1509 0.9961 3039549 ChemDiv3_013639 Cc1ccc(cc1)C2=NN(CCC(=O)NCC=C)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L22 compound treatment 0.287 0.0668 0.96 0.314 0.0736 1.23 1.5485 0.992 3039550 ChemDiv3_013640 Cc1ccc(Nc2cc(C(=O)NCC3CCCO3)c4ccccc4n2)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L23 mock treatment 0.236 0.0158 0.23 0.262 0.0216 0.36 0.4155 0.9742 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 L24 mock treatment 0.198 -0.0222 -0.32 0.237 -0.00344 -0.06 -0.2655 -0.822 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M01 compound treatment 0.248 0.0278 0.4 0.253 0.0126 0.21 0.4301 0.9561 3039551 ChemDiv3_013641 CCC1CCCCN1CCCNC(=O)c2ccc(Sc3ccc(C)cc3)c(NC(=O)C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M02 compound treatment 0.265 0.0448 0.64 0.305 0.0646 1.08 1.2192 0.9685 3039553 ChemDiv3_013642 CC1CCCC(NC(=O)C2CCN(CC2)C(=O)N(C)C)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M03 compound treatment 0.281 0.0608 0.87 0.315 0.0746 1.25 1.4997 0.9842 3039554 ChemDiv3_013643 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M04 compound treatment 0.267 0.0468 0.67 0.273 0.0326 0.55 0.8596 0.995 3122897 ChemDiv3_013644 CC(C)N(C(C)c1ccccn1)C(=S)Nc2ccc(Oc3ccccc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M05 compound treatment 0.277 0.0568 0.81 0.208 -0.0324 -0.54 0.1893 0.1936 3039557 ChemDiv3_013645 Cc1ccc(CCNC(=O)C2CCN(CC2)c3nc4ccccc4o3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M06 compound treatment 0.264 0.0438 0.63 0.303 0.0626 1.05 1.1853 0.9695 3122898 ChemDiv3_013646 CC(NC(=O)Cn1nc(ccc1=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M07 compound treatment 0.257 0.0368 0.53 0.283 0.0426 0.71 0.8771 0.9887 3039558 ChemDiv3_013647 CCc1ccc(CNC(=O)CCc2cn(Cc3ccccc3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M08 compound treatment 0.279 0.0588 0.84 0.284 0.0436 0.73 1.1115 0.9976 3122899 ChemDiv3_013648 O=C(CCN1C(=O)COc2ccccc12)NCCN3CCc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M09 compound treatment 0.186 -0.0342 -0.49 0.184 -0.0564 -0.95 -1.0159 -0.9528 3122900 ChemDiv3_013649 CC(C)CCN(C)C1CCN(CC1)C(=O)Nc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M10 compound treatment 0.324 0.104 1.48 0.279 0.0386 0.65 1.5073 0.9308 3039560 ChemDiv3_013650 Clc1ccc(CSCCC(=O)N2CCN(CC2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M11 compound treatment 0.27 0.0498 0.71 0.274 0.0336 0.56 0.9018 0.9933 3122901 ChemDiv3_013651 CC1CCN(CC1)C(=O)CNC(=O)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M12 compound treatment 0.234 0.0138 0.2 0.291 0.0506 0.85 0.7395 0.8488 3039562 ChemDiv3_013652 CCS(=O)(=O)N1CCC(CC1)C(=O)NCCCN2CCN(CC2)c3ccccc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M13 compound treatment 0.252 0.0318 0.45 0.245 0.00456 0.08 0.3756 0.8147 3122902 ChemDiv3_013653 CCCCN(CC)S(=O)(=O)c1ccc2[nH]c(=O)cc(C(=O)NCCc3ccc(Cl)cc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M14 compound treatment 0.219 -0.00122 -0.02 0.304 0.0636 1.07 0.742 0.6955 3122903 ChemDiv3_013654 CC1CCCCC1NC(=O)CCSCc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M15 compound treatment 0.206 -0.0142 -0.2 0.227 -0.0134 -0.23 -0.3033 -0.9987 3039565 ChemDiv3_013655 CCc1ccc(CNC(=O)c2ccc3n(cnc3c2)C4CCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M16 compound treatment 0.287 0.0668 0.96 0.252 0.0116 0.19 0.8127 0.8337 3122904 ChemDiv3_013656 Fc1ccc(cc1Cl)N2CC(CC2=O)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M17 compound treatment 0.247 0.0268 0.38 0.286 0.0456 0.76 0.8116 0.9489 3122905 ChemDiv3_013657 CC1CCCC(C)N1CCCNC(=O)C2N(CCc3ccc(Cl)cc3)C(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M18 compound treatment 0.247 0.0268 0.38 0.317 0.0766 1.29 1.1795 0.8796 3039568 ChemDiv3_013658 Cc1ccc(CS(=O)(=O)CCC(=O)NC2CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M19 compound treatment 0.251 0.0308 0.44 0.288 0.0476 0.8 0.8758 0.9607 3039569 ChemDiv3_013659 Cc1ccc(CNC(=O)C2CCN(CC2)S(=O)(=O)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M20 compound treatment 0.237 0.0168 0.24 0.297 0.0566 0.95 0.841 0.8589 3122906 ChemDiv3_013660 CC(C)CCNC(=O)c1ccc(CSCc2ccc(C)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M21 compound treatment 0.046 -0.174 -2.49 0.051 -0.189 -3.18 -4.0103 -0.9927 3039572 ChemDiv3_013661 Clc1ccc(SCCNC(=S)Nc2cccc(Cl)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M22 compound treatment 0.279 0.0588 0.84 0.283 0.0426 0.71 1.0997 0.9967 3122907 ChemDiv3_013662 COc1cccc(CNC(=O)CCn2nc(ccc2=O)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M23 mock treatment 0.216 -0.00422 -0.06 0.264 0.0236 0.4 0.237 0.5924 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 M24 mock treatment 0.205 -0.0152 -0.22 0.245 0.00456 0.08 -0.0998 -0.4324 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N01 compound treatment 0.239 0.0188 0.27 0.305 0.0646 1.08 0.9562 0.8565 3122908 ChemDiv3_013663 Cc1ccccc1CS(=O)(=O)Cc2ccc(o2)C(=O)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N02 compound treatment 0.262 0.0418 0.6 0.274 0.0336 0.56 0.8209 0.9996 3039574 ChemDiv3_013664 O=C(CN1C(=O)/C(=C/c2ccccc2)/Sc3ccccc13)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N03 compound treatment 0.283 0.0628 0.9 0.305 0.0646 1.08 1.4012 0.9956 3039631 ChemDiv3_013665 CC(C)CCNC(=O)C1CCC(=O)N1CCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N04 compound treatment 0.268 0.0478 0.68 0.256 0.0156 0.26 0.668 0.9129 3039632 ChemDiv3_013666 Cc1ccccc1NS(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCc5ccccc45)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N05 compound treatment 0.241 0.0208 0.3 0.303 0.0626 1.05 0.9527 0.873 3039634 ChemDiv3_013667 O=C(c1ccc2n(cnc2c1)C3CCCCC3)n4ccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N06 compound treatment 0.314 0.0938 1.34 0.327 0.0866 1.45 1.9759 0.9992 3039635 ChemDiv3_013668 COc1cccc(NC(=S)N(CCN(C)C)C(C)c2ccncc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N07 compound treatment 0.17 -0.0502 -0.72 0.203 -0.0374 -0.63 -0.9522 -0.9978 3039637 ChemDiv3_013669 CCOc1ccccc1NC(=S)NCC(C)CSc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N08 compound treatment 0.204 -0.0162 -0.23 0.297 0.0566 0.95 0.5072 0.519 3039638 ChemDiv3_013670 COC(CNC(=O)c1coc2nc3ccccc3nc12)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N09 compound treatment 0.255 0.0348 0.5 0.301 0.0606 1.02 1.0705 0.946 3122909 ChemDiv3_013671 CN1CCN(CC1)C(=O)c2ccc(c(NC(=O)C)c2)S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N10 compound treatment 0.265 0.0448 0.64 0.309 0.0686 1.15 1.2666 0.9617 3039640 ChemDiv3_013672 CC1CC(C)CN(C1)C(=O)c2ccc(CNS(=O)(=O)c3ccc(F)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N11 compound treatment 0.287 0.0668 0.96 0.278 0.0376 0.63 1.1212 0.9797 3122910 ChemDiv3_013673 CCCS(=O)(=O)N1CCCC(C1)C(=O)NC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N12 compound treatment 0.312 0.0918 1.31 0.267 0.0266 0.45 1.2435 0.8969 3039642 ChemDiv3_013674 CNC(=O)C1CCC(CNS(=O)(=O)c2ccc(C)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N13 compound treatment 0.314 0.0938 1.34 0.266 0.0256 0.43 1.2519 0.8889 3122911 ChemDiv3_013675 CN(Cc1ccccc1)C(=O)Cn2nc(ccc2=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N14 compound treatment 0.269 0.0488 0.7 0.319 0.0786 1.32 1.4258 0.9557 3122912 ChemDiv3_013676 O=C(NCc1ccccn1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N15 compound treatment 0.303 0.0828 1.18 0.324 0.0836 1.4 1.829 0.9965 3039644 ChemDiv3_013677 CCCCN(CC)Cc1ccc(CNC(=O)Nc2ccccc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N16 compound treatment 0.255 0.0348 0.5 0.259 0.0186 0.31 0.5721 0.9746 3122913 ChemDiv3_013678 CC1CCCCC1N2CCC(CNC(=S)Nc3cccc(Cl)c3)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N17 compound treatment 0.268 0.0478 0.68 0.315 0.0746 1.25 1.3682 0.9595 3039647 ChemDiv3_013679 COc1ccc(cc1)C2=NN(CC(=O)N3CCCC3)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N18 compound treatment 0.265 0.0448 0.64 0.24 -4.38E-4 -0.01 0.4477 0.699 3122914 ChemDiv3_013680 CC(N(CCCN1CCOCC1)C(=S)Nc2cc(C)cc(C)c2)c3cc4ccccc4o3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N19 compound treatment 0.291 0.0708 1.01 0.306 0.0656 1.1 1.494 0.9991 3122915 ChemDiv3_013681 CCc1ccc(NC(=O)N2CCC(C2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N20 compound treatment 0.241 0.0208 0.3 0.313 0.0726 1.22 1.0714 0.8546 3039649 ChemDiv3_013682 CCN1CCN(CC1)C(=O)c2ccc(CS(=O)(=O)Cc3ccccc3F)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N21 compound treatment 0.254 0.0338 0.48 0.324 0.0836 1.4 1.3334 0.8989 3123093 ChemDiv3_013683 CCOc1ccc(NC(=O)NCc2cccn2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N22 compound treatment 0.191 -0.0292 -0.42 0.273 0.0326 0.55 0.0909 0.1322 3123094 ChemDiv3_013684 CC1CC(C)CN(C1)C(=O)c2cc(Nc3ccc(C)c(C)c3)nc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N23 mock treatment 0.262 0.0418 0.6 0.29 0.0496 0.83 1.0108 0.9868 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 N24 mock treatment 0.236 0.0158 0.23 0.254 0.0136 0.23 0.3206 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O01 compound treatment 0.285 0.0648 0.93 0.277 0.0366 0.61 1.0891 0.98 3039653 ChemDiv3_013685 CN(C)CCNC(=O)c1ccc(Sc2ccc(C)cc2)c(NC(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O02 compound treatment 0.295 0.0748 1.07 0.251 0.0106 0.18 0.8817 0.8132 3123095 ChemDiv3_013686 CC(NC(=O)C1CCN(CC1)C(=O)N(C)C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O03 compound treatment 0.264 0.0438 0.63 0.285 0.0446 0.75 0.9717 0.9961 3039655 ChemDiv3_013687 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O04 compound treatment 0.284 0.0638 0.91 0.274 0.0336 0.56 1.0434 0.9732 3123096 ChemDiv3_013688 CN(C)C(=O)N1CCC(CC1)C(=O)N2CCC3(CC2)OCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O05 compound treatment 0.264 0.0438 0.63 0.314 0.0736 1.23 1.3159 0.9505 3123097 ChemDiv3_013689 CCc1ccc(CNC(=O)C2CCN(CC2)c3nc4ccccc4o3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O06 compound treatment 0.26 0.0398 0.57 0.296 0.0556 0.93 1.0618 0.9719 3039711 ChemDiv3_013690 COc1ccc(Br)cc1CNC(=O)C2CCCN(C2)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O07 compound treatment 0.238 0.0178 0.25 0.303 0.0626 1.05 0.9223 0.8537 3039713 ChemDiv3_013691 CC1CCCCC1NC(=O)C2CCCN(C2)c3nc4ccccc4o3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O08 compound treatment 0.295 0.0748 1.07 0.307 0.0666 1.12 1.5463 0.9998 3039714 ChemDiv3_013692 Cc1ccc(Cl)cc1N2CCN(CC2)C(=O)CCN3C(=O)COc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O09 compound treatment 0.234 0.0138 0.2 0.299 0.0586 0.98 0.8344 0.8323 3039715 ChemDiv3_013693 CC(C)CCN(C)C1CCN(CC1)S(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O10 compound treatment 0.234 0.0138 0.2 0.297 0.0566 0.95 0.8107 0.8361 3039717 ChemDiv3_013694 CC(C)CCNC(=O)C1CCCN(C1)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O11 compound treatment 0.234 0.0138 0.2 0.314 0.0736 1.23 1.0124 0.8097 3039718 ChemDiv3_013695 OC(=O)c1c2CN(CCc2nc3ccccc13)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O12 compound treatment 0.262 0.0418 0.6 0.297 0.0566 0.95 1.0939 0.9751 3039719 ChemDiv3_013696 CCS(=O)(=O)N1CCC(CC1)C(=O)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O13 compound treatment 0.236 0.0158 0.23 0.242 0.00156 0.03 0.1782 0.784 3123098 ChemDiv3_013697 CC(C)N(C1CCN(CC1)C(=O)C)C(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O14 compound treatment 0.267 0.0468 0.67 0.317 0.0766 1.29 1.3818 0.9538 3039721 ChemDiv3_013698 Cc1ccc(CSCC(=O)NCCc2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O15 compound treatment 0.3 0.0798 1.14 0.313 0.0726 1.22 1.6681 0.9995 3123099 ChemDiv3_013699 CCC1Oc2ccccc2N(CC(=O)N3CC(C)CC(C)C3)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O16 compound treatment 0.228 0.00778 0.11 0.316 0.0756 1.27 0.9755 0.7662 3123100 ChemDiv3_013700 O=C(NCCc1ccccc1)C2CCC(=O)N2C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O17 compound treatment 0.222 0.00178 0.03 0.253 0.0126 0.21 0.1671 0.7868 3039724 ChemDiv3_013701 C=CCNC(=O)CCN1C(=O)COc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O18 compound treatment 0.285 0.0648 0.93 0.245 0.00456 0.08 0.7094 0.7629 3123101 ChemDiv3_013702 Cc1ccc(cc1)c2ccc(=O)n(CC(=O)NC3CCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O19 compound treatment 0.291 0.0708 1.01 0.301 0.0606 1.02 1.4347 1.0 3039726 ChemDiv3_013703 CC(C)CCN(C1CCN(CC1)C(C)C)C(=S)Nc2ccc(cc2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O20 compound treatment 0.226 0.00578 0.08 0.315 0.0746 1.25 0.9434 0.7522 3123102 ChemDiv3_013704 Cc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)N3CCc4ccccc4C3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O21 compound treatment 0.252 0.0318 0.45 0.263 0.0226 0.38 0.5892 0.9959 3039728 ChemDiv3_013705 CC(C)N(C(C)c1ccccn1)C(=S)Nc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O22 compound treatment 0.22 -2.19E-4 0.0 0.254 0.0136 0.23 0.1587 0.6973 3123103 ChemDiv3_013706 O=C(CCn1nc(ccc1=O)c2ccccc2)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O23 mock treatment 0.222 0.00178 0.03 0.227 -0.0134 -0.23 -0.1415 -0.6233 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 O24 mock treatment 0.206 -0.0142 -0.2 0.235 -0.00544 -0.09 -0.2083 -0.9346 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P01 compound treatment 0.264 0.0438 0.63 0.26 0.0196 0.33 0.675 0.9546 3123104 ChemDiv3_013707 O=C(CCN1N=C(CCC1=O)c2ccccc2)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P02 compound treatment 0.267 0.0468 0.67 0.263 0.0226 0.38 0.7409 0.9637 3039730 ChemDiv3_013708 O=C(CN1C(=O)/C(=C/c2ccccc2)/Sc3ccccc13)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P03 compound treatment 0.269 0.0488 0.7 0.286 0.0456 0.76 1.0341 0.999 3123105 ChemDiv3_013709 COc1ccc(CCN2CC(CC2=O)C(=O)NCc3ccc(F)cc3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P04 compound treatment 0.265 0.0448 0.64 0.29 0.0496 0.83 1.0411 0.9917 3123106 ChemDiv3_013710 CCCCN(C)C(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)Nc3cccc(OC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P05 compound treatment 0.261 0.0408 0.58 0.308 0.0676 1.13 1.2143 0.9522 3039732 ChemDiv3_013711 O=C(NCCN1CCCCCC1)c2ccc3n(cnc3c2)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P06 compound treatment 0.277 0.0568 0.81 0.273 0.0326 0.55 0.9608 0.9814 3123107 ChemDiv3_013712 CC1CCCCC1NC(=O)c2ccc3Sc4ccccc4C(=O)N(CC=C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P07 compound treatment 0.262 0.0418 0.6 0.282 0.0416 0.7 0.9159 0.997 3039734 ChemDiv3_013713 Fc1ccc(cc1Cl)N2CC(CC2=O)C(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P08 compound treatment 0.224 0.00378 0.05 0.3 0.0596 1.0 0.7451 0.7443 3123108 ChemDiv3_013714 CC1CCCN(CCCNC(=O)c2coc3nc4ccccc4nc23)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P09 compound treatment 0.262 0.0418 0.6 0.307 0.0666 1.12 1.2126 0.957 3039736 ChemDiv3_013715 CCS(=O)(=O)N1CCCC(C1)C(=O)N2CCC3(CC2)OCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P10 compound treatment 0.237 0.0168 0.24 0.342 0.102 1.7 1.3751 0.7988 3123109 ChemDiv3_013716 CCCN(CCC)C(=O)c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P11 compound treatment 0.249 0.0288 0.41 0.297 0.0566 0.95 0.9624 0.9301 3039794 ChemDiv3_013717 CCCS(=O)(=O)N1CCCC(C1)C(=O)N2CCN(CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P12 compound treatment 0.292 0.0718 1.03 0.319 0.0786 1.32 1.6584 0.9923 3039795 ChemDiv3_013718 Clc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P13 compound treatment 0.278 0.0578 0.83 0.289 0.0486 0.82 1.1608 1.0 3039797 ChemDiv3_013719 COc1ccc(NC(=O)NCC(C)CSc2ccc(Cl)cc2)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P14 compound treatment 0.284 0.0638 0.91 0.269 0.0286 0.48 0.9841 0.9549 3039798 ChemDiv3_013720 O=C(NC1CCCCC1)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P15 compound treatment 0.237 0.0168 0.24 0.264 0.0236 0.4 0.4494 0.9714 3039800 ChemDiv3_013721 CCOc1ccc(NC(=O)N(CCC(C)C)C(C)c2cccs2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P16 compound treatment 0.26 0.0398 0.57 0.26 0.0196 0.33 0.6345 0.9659 3039801 ChemDiv3_013722 Fc1cc(F)cc(NC(=S)NCCN(C2CCCC2)C3CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P17 compound treatment 0.247 0.0268 0.38 0.28 0.0396 0.66 0.7404 0.9658 3123110 ChemDiv3_013723 COc1ccc(cc1)C2=NN(CC(=O)NCc3ccc4OCOc4c3)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P18 compound treatment 0.247 0.0268 0.38 0.265 0.0246 0.41 0.5624 0.9993 3039803 ChemDiv3_013724 CCN1CCCc2cc(CN(CCN3CCOCC3)C(=S)Nc4c(C)cc(C)cc4C)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P19 compound treatment 0.24 0.0198 0.28 0.268 0.0276 0.46 0.5272 0.9722 3123111 ChemDiv3_013725 Cc1c(Cl)cccc1NC(=S)NCc2cccn2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P20 compound treatment 0.267 0.0468 0.67 0.306 0.0656 1.1 1.2513 0.9716 3123112 ChemDiv3_013726 CC(C)CCNC(=O)c1ccc(cc1)N2CCCC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P21 compound treatment 0.274 0.0538 0.77 0.255 0.0146 0.24 0.7168 0.888 3039807 ChemDiv3_013727 COCCN(C(C)c1cccnc1)C(=S)Nc2c(C)cccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P22 compound treatment 0.255 0.0348 0.5 0.258 0.0176 0.29 0.5602 0.9688 3123113 ChemDiv3_013728 Cc1ccc(Nc2cc(C(=O)N3CCCC3)c4ccccc4n2)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P23 mock treatment 0.231 0.0108 0.15 0.222 -0.0184 -0.31 -0.1098 -0.3175 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2039 P24 mock treatment 0.217 -0.00322 -0.05 0.243 0.00256 0.04 -0.0021 -0.034 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A01 compound treatment 0.259 0.00875 0.13 0.207 -0.0276 -0.46 -0.2394 -0.4984 3123114 ChemDiv3_013729 CC(C)CCNC(=O)c1cc(Nc2ccc(C)c(C)c2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A02 compound treatment 0.224 -0.0262 -0.38 0.209 -0.0256 -0.43 -0.5696 -0.9977 3039810 ChemDiv3_013730 CC(C)N(CCc1ccncc1)C(=S)NCC2CCCO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A03 compound treatment 0.27 0.0198 0.28 0.215 -0.0196 -0.33 -0.0332 -0.0764 3123115 ChemDiv3_013731 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(/C=C/4\Oc5ccccc5NC4=O)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A04 compound treatment 0.266 0.0158 0.23 0.236 0.00137 0.02 0.1756 0.7755 3039812 ChemDiv3_013732 CCCNC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A05 compound treatment 0.257 0.00675 0.1 0.225 -0.00962 -0.16 -0.046 -0.2442 3123116 ChemDiv3_013733 CCCN1CCCc2cc(CN(CCOC)C(=S)Nc3ccccc3OC)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A06 compound treatment 0.261 0.0107 0.15 0.243 0.00837 0.14 0.2081 0.999 3123117 ChemDiv3_013734 Fc1ccc(CN2C(=O)/C(=C/c3ccccc3)/Sc4ccc(cc24)C(=O)NCC5CCCO5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A07 compound treatment 0.218 -0.0323 -0.46 0.217 -0.0176 -0.3 -0.5354 -0.9769 3039815 ChemDiv3_013735 O=C(CCN1N=C(CCC1=O)c2ccccc2)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A08 compound treatment 0.218 -0.0323 -0.46 0.204 -0.0306 -0.51 -0.6896 -0.9985 3123118 ChemDiv3_013736 CCN1CCN(CC1)C(=O)c2ccc(/C=C\3/Sc4ccccc4N(Cc5ccccc5C)C3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A09 compound treatment 0.255 0.00475 0.07 0.228 -0.00662 -0.11 -0.0306 -0.2347 3039817 ChemDiv3_013737 COc1ccc(Nc2cc(C(=O)NCCCN3CCCC3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A10 compound treatment 0.235 -0.0153 -0.22 0.211 -0.0236 -0.4 -0.4346 -0.9604 3039869 ChemDiv3_013738 CCCNC(=O)c1ccc2S/C(=C\c3ccccc3)/C(=O)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A11 compound treatment 0.289 0.0388 0.55 0.237 0.00237 0.04 0.4201 0.756 3039870 ChemDiv3_013739 Cc1cccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCCC3=CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A12 compound treatment 0.272 0.0217 0.31 0.232 -0.00262 -0.04 0.1888 0.601 3039872 ChemDiv3_013740 CCOC(=O)N1CCc2c(C(=O)Nc3ccc(OC)cc3OC)c(NCc4cccnc4)sc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A13 compound treatment 0.234 -0.0163 -0.23 0.208 -0.0266 -0.45 -0.4803 -0.9536 3039873 ChemDiv3_013741 O=C(NC1CC1)c2ccc(CS(=O)c3ccccc3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A14 compound treatment 0.25 -2.5E-4 0.0 0.211 -0.0236 -0.4 -0.2829 -0.7135 3039875 ChemDiv3_013742 Fc1ccc(CNC(=O)CC2CC3CCC2C3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A15 compound treatment 0.253 0.00275 0.04 0.244 0.00937 0.16 0.1391 0.8575 3039876 ChemDiv3_013743 Fc1cccc(CSCc2ccc(o2)C(=O)NC3CC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A16 compound treatment 0.251 7.5E-4 0.01 0.247 0.0124 0.21 0.1545 0.7426 3123119 ChemDiv3_013744 FC(F)(F)c1ccccc1CNC(=O)c2ccc3ccccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A17 compound treatment 0.219 -0.0313 -0.45 0.241 0.00637 0.11 -0.2404 -0.5231 3039878 ChemDiv3_013745 CN(CCN1CCOCC1)C2CCN(CC2)C(=S)Nc3ccc(C)c(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A18 compound treatment 0.258 0.00775 0.11 0.226 -0.00862 -0.14 -0.024 -0.1315 3123120 ChemDiv3_013746 CSc1ncccc1C(=O)Nc2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A19 compound treatment 0.221 -0.0293 -0.42 0.233 -0.00162 -0.03 -0.3151 -0.7516 3123301 ChemDiv3_013747 O=C(CN1CCOc2ccccc12)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A20 compound treatment 0.231 -0.0193 -0.28 0.231 -0.00362 -0.06 -0.2377 -0.843 3039880 ChemDiv3_013748 FC(F)(F)c1cccc(c1)N2CCN(CC2)C(=O)Cc3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A21 compound treatment 0.26 0.00975 0.14 0.226 -0.00862 -0.14 -0.0037 -0.0186 3123302 ChemDiv3_013749 CSc1cccc(NC(=S)N(CCc2ccncc2)C(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A22 compound treatment 0.25 -2.5E-4 0.0 0.234 -6.25E-4 -0.01 -0.0099 -0.8974 3039882 ChemDiv3_013750 Cc1ccc(cc1)C(=O)CCC(=O)NC2=NCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A23 mock treatment 0.211 -0.0393 -0.56 0.209 -0.0256 -0.43 -0.7011 -0.9913 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 A24 mock treatment 0.203 -0.0473 -0.68 0.218 -0.0166 -0.28 -0.6752 -0.9234 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B01 compound treatment 0.256 0.00575 0.08 0.218 -0.0166 -0.28 -0.1392 -0.4783 3123303 ChemDiv3_013751 O=C(CCCC(=O)c1ccccc1)Nc2nc[nH]n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B02 compound treatment 0.252 0.00175 0.03 0.206 -0.0286 -0.48 -0.322 -0.6694 3123304 ChemDiv3_013752 COC(=O)C1=CN(C=C(C1c2ccc(cc2)C(C)C)C(=O)OC)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B03 compound treatment 0.257 0.00675 0.1 0.235 3.75E-4 0.01 0.0727 0.7516 3039884 ChemDiv3_013753 O=C(CCC(=O)c1ccccc1)Nc2ccc(cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B04 compound treatment 0.254 0.00375 0.05 0.266 0.0314 0.53 0.4103 0.7751 1152542 ChemDiv3_013754 CCOC(=O)c1sc2ncnc(Nc3ccc(OCC)cc3)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B05 compound treatment 0.263 0.0127 0.18 0.255 0.0204 0.34 0.3708 0.9567 3039887 ChemDiv3_013755 COc1ccc(cc1)C(=O)CCC(=O)NC2=NCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B06 compound treatment 0.253 0.00275 0.04 0.259 0.0244 0.41 0.3171 0.7715 1277091 ChemDiv3_013756 CC(C)N(C(C)C)C(=O)Cc1c(O)c2ccccc2[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B07 compound treatment 0.264 0.0138 0.2 0.262 0.0274 0.46 0.464 0.9283 3039889 ChemDiv3_013757 Cc1ccc(C)c(NC(=O)c2cccs2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B08 compound treatment 0.287 0.0367 0.53 0.253 0.0184 0.31 0.5898 0.9677 3123305 ChemDiv3_013758 CCCCn1c(=O)c(c(O)c2ccccc12)[n+]3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B09 compound treatment 0.273 0.0227 0.33 0.255 0.0204 0.34 0.4719 0.9997 1250014 ChemDiv3_013759 CCOC(=O)c1c(C)n(CCc2c[nH]c3ccccc23)c(C)c1C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B10 compound treatment 0.254 0.00375 0.05 0.264 0.0294 0.49 0.3866 0.7794 1390876 ChemDiv3_013760 CCOc1ccc(CCNC(=O)c2cn(CC)c3nc(C)ccc3c2=O)cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B11 compound treatment 0.295 0.0447 0.64 0.251 0.0164 0.27 0.647 0.9287 3123306 ChemDiv3_013761 CN1/C(=C\C(=O)c2cccc(Cl)c2)/C(C)(C)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B12 compound treatment 0.251 7.5E-4 0.01 0.208 -0.0266 -0.45 -0.3084 -0.6899 1369757 ChemDiv3_013762 COc1nc(NCC=C)nc(Nc2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B13 compound treatment 0.292 0.0418 0.6 0.255 0.0204 0.34 0.6641 0.965 3039948 ChemDiv3_013763 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B14 compound treatment 0.263 0.0127 0.18 0.245 0.0104 0.17 0.2521 0.9997 1530019 ChemDiv3_013764 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N2CCN(CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B15 compound treatment 0.275 0.0248 0.35 0.267 0.0324 0.54 0.6346 0.9785 1572652 ChemDiv3_013765 CC(C)CCNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B16 compound treatment 0.289 0.0388 0.55 0.226 -0.00862 -0.14 0.2896 0.5055 1260656 ChemDiv3_013766 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B17 compound treatment 0.288 0.0377 0.54 0.248 0.0134 0.22 0.5405 0.9244 3039950 ChemDiv3_013767 CCN(CC)S(=O)(=O)c1ccc2[nH]cc(C(=O)N3CCC(C)CC3)c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B18 compound treatment 0.257 0.00675 0.1 0.243 0.00837 0.14 0.1677 0.9832 1376292 ChemDiv3_013768 CN(c1ccccc1)c2ncnc3sc(C(=O)Nc4ccc(F)cc4F)c(C)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B19 compound treatment 0.272 0.0217 0.31 0.243 0.00837 0.14 0.3194 0.9355 3123307 ChemDiv3_013769 CCOC(=O)C1=C(Nc2ncnn2C1c3ccc(F)cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B20 compound treatment 0.281 0.0308 0.44 0.249 0.0144 0.24 0.4816 0.96 3039952 ChemDiv3_013770 O=C(Cn1c(=O)oc2ccccc12)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B21 compound treatment 0.289 0.0388 0.55 0.248 0.0134 0.22 0.5507 0.9208 3123308 ChemDiv3_013771 COc1ccc(cc1O)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B22 compound treatment 0.266 0.0158 0.23 0.232 -0.00262 -0.04 0.1281 0.5582 3039954 ChemDiv3_013772 Cc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B23 mock treatment 0.265 0.0147 0.21 0.236 0.00137 0.02 0.1655 0.7798 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 B24 mock treatment 0.262 0.0118 0.17 0.223 -0.0116 -0.2 -0.0191 -0.0743 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C01 compound treatment 0.235 -0.0153 -0.22 0.213 -0.0216 -0.36 -0.4109 -0.9703 3123309 ChemDiv3_013773 Fc1cccc(CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)N5CCCCC5)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C02 compound treatment 0.263 0.0127 0.18 0.268 0.0334 0.56 0.5251 0.8913 3123310 ChemDiv3_013774 Cc1ccc(cc1)C2CCN(C2)C(=S)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C03 compound treatment 0.243 -0.00725 -0.1 0.21 -0.0246 -0.41 -0.3656 -0.8579 3039956 ChemDiv3_013775 CCOC(=O)C1CCCN(C1)C(=O)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C04 compound treatment 0.288 0.0377 0.54 0.218 -0.0166 -0.28 0.1845 0.3036 3123311 ChemDiv3_013776 CN1C(=O)CS(=O)c2ccc(cc12)C(=O)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C05 compound treatment 0.296 0.0457 0.65 0.049 -0.186 -3.12 -1.7403 -0.5467 3123312 ChemDiv3_013777 CCN1CCCc2cc(CN(C3CCCC3)C(=S)Nc4ccc(OC)cc4)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C06 compound treatment 0.343 0.0928 1.33 0.067 -0.168 -2.81 -1.0513 -0.338 3123313 ChemDiv3_013778 COc1ccc(/C=C\2/Sc3ccc(cc3NC2=O)C(=O)NC4CCCc5ccccc45)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C07 compound treatment 0.381 0.131 1.87 0.25 0.0154 0.26 1.5049 0.7971 3039959 ChemDiv3_013779 CC(C)N(CCCn1cccc1)C(=S)Nc2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C08 compound treatment 0.346 0.0958 1.37 0.254 0.0194 0.33 1.1984 0.8513 3039961 ChemDiv3_013780 COc1ccccc1c2c(C)nn3c(cc(C)nc23)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C09 compound treatment 0.375 0.125 1.78 0.114 -0.121 -2.02 -0.1698 -0.0629 3123314 ChemDiv3_013781 O=C(CCN1N=C(CCC1=O)c2ccccc2)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C10 compound treatment 0.337 0.0867 1.24 0.122 -0.113 -1.89 -0.4592 -0.2031 3123315 ChemDiv3_013782 COc1ccc(cc1OC)C2OC(=O)CC2C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C11 compound treatment 0.365 0.115 1.64 0.268 0.0334 0.56 1.5567 0.8976 3039963 ChemDiv3_013783 Cc1cccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCCCN3CCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C12 compound treatment 0.293 0.0428 0.61 0.215 -0.0196 -0.33 0.1995 0.2872 1503664 ChemDiv3_013784 COc1cccc2C3CC(=NN3C4(CCCCC4)Oc12)c5ccco5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C13 compound treatment 0.298 0.0478 0.68 0.231 -0.00362 -0.06 0.4399 0.6416 3123316 ChemDiv3_013785 Cc1cc(N2CCN(CC2)c3ccccc3)n4nc(cc4n1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C14 compound treatment 0.381 0.131 1.87 0.046 -0.189 -3.17 -0.9162 -0.2492 3039966 ChemDiv3_013786 CCOc1ccc(NC(=O)CC2CC3CCC2C3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C15 compound treatment 0.258 0.00775 0.11 0.233 -0.00162 -0.03 0.0591 0.5177 3123317 ChemDiv3_013787 COC(CN(C)c1cc(C)nc2c(c(C)nn12)c3ccc(Cl)cc3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C16 compound treatment 0.353 0.103 1.47 0.053 -0.182 -3.05 -1.1163 -0.3299 1340676 ChemDiv3_013788 Cc1cccc(NC(=O)c2ccc3ccccc3c2)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C17 compound treatment 0.321 0.0707 1.01 0.225 -0.00962 -0.16 0.6014 0.5868 3038835 ChemDiv3_013789 COc1ccc(cc1)C2=NN(CCC(=O)NCCN3CCN(CC3)c4cccc(Cl)c4)C(=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C18 compound treatment 0.14 -0.11 -1.58 0.068 -0.167 -2.8 -3.0926 -0.9632 3038751 ChemDiv3_013790 CSc1ncccc1C(=O)Nc2ccccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C19 compound treatment 0.378 0.128 1.83 0.209 -0.0256 -0.43 0.988 0.5263 3038753 ChemDiv3_013791 CC(C)CCNC(=O)CN1CCOc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C20 compound treatment 0.362 0.112 1.6 0.054 -0.181 -3.03 -1.0134 -0.2957 3038754 ChemDiv3_013792 Clc1cc(NC(=O)Cc2cccc3ccccc23)ccc1N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C21 compound treatment 0.308 0.0578 0.83 0.241 0.00637 0.11 0.6598 0.7921 3038756 ChemDiv3_013793 CCc1ccccc1NC(=S)N(CCc2ccncc2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C22 compound treatment 0.087 -0.163 -2.34 0.217 -0.0176 -0.3 -1.8603 -0.7904 3038757 ChemDiv3_013794 Cc1nnc(NC(=O)CCC(=O)c2ccc(C)cc2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C23 mock treatment 0.23 -0.0203 -0.29 0.235 3.75E-4 0.01 -0.2004 -0.6916 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 C24 mock treatment 0.262 0.0118 0.17 0.208 -0.0266 -0.45 -0.1971 -0.4129 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D01 compound treatment 0.272 0.0217 0.31 0.241 0.00637 0.11 0.2956 0.8986 3038759 ChemDiv3_013795 Cc1ccc(NC(=O)CCCC(=O)c2ccccc2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D02 compound treatment 0.249 -0.00125 -0.02 0.216 -0.0186 -0.31 -0.2337 -0.7463 3038761 ChemDiv3_013796 CCOC(=O)C1=CN(C)C=C(C1c2cccc(OCc3ccccc3)c2)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D03 compound treatment 0.37 0.12 1.71 0.269 0.0344 0.58 1.6191 0.8958 3123318 ChemDiv3_013797 Brc1ccc(o1)C(=O)Nc2ccc(cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D04 compound treatment 0.364 0.114 1.63 0.296 0.0614 1.03 1.8789 0.9757 1126343 ChemDiv3_013798 CCOC(CNc1nc(C)nc2sc3CCCCc3c12)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D05 compound treatment 0.333 0.0828 1.18 0.265 0.0304 0.51 1.1974 0.9291 3123319 ChemDiv3_013799 COc1ccc(NC(=O)CCC(=O)c2ccc(OC)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D06 compound treatment 0.351 0.101 1.44 0.231 -0.00362 -0.06 0.976 0.6767 1647698 ChemDiv3_013800 CCOC(=O)Cc1c(O)c2ccccc2[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D07 compound treatment 0.382 0.132 1.88 0.261 0.0264 0.44 1.6456 0.8501 3123320 ChemDiv3_013801 COc1ccc(CNC(=O)c2cccs2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D08 compound treatment 0.353 0.103 1.47 0.235 3.75E-4 0.01 1.0437 0.7101 3123321 ChemDiv3_013802 CC(C)Cn1c(=O)c(c(O)c2ccccc12)[n+]3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D09 compound treatment 0.345 0.0948 1.36 0.259 0.0244 0.41 1.2476 0.8813 3038765 ChemDiv3_013803 CCOC(=O)C1=C(C)NN=C(C)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D10 compound treatment 0.394 0.144 2.06 0.271 0.0364 0.61 1.8856 0.8791 1661248 ChemDiv3_013804 O=C(CCn1c(=S)oc2ccccc12)NN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D11 compound treatment 0.334 0.0838 1.2 0.259 0.0244 0.41 1.1364 0.8977 3123322 ChemDiv3_013805 CS(=O)(=O)N1CCC(CC1)c2noc(n2)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D12 compound treatment 0.322 0.0717 1.03 0.229 -0.00562 -0.09 0.6589 0.6394 1237741 ChemDiv3_013806 COc1nc(NCCO)nc(Nc2ccc(I)cc2C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D13 compound treatment 0.36 0.11 1.57 0.262 0.0274 0.46 1.4349 0.8773 1602373 ChemDiv3_013807 COc1ccc(Cl)cc1NC(=O)c2sc3nc(C)n(C)c(=O)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D14 compound treatment 0.366 0.116 1.66 0.269 0.0344 0.58 1.5787 0.9004 3123323 ChemDiv3_013808 OC1(CCN(CC1)S(=O)(=O)c2cccc3nsnc23)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D15 compound treatment 0.431 0.181 2.59 0.277 0.0424 0.71 2.3311 0.8693 1246763 ChemDiv3_013809 CCN(c1cccc(C)c1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCCc4ccccc4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D16 compound treatment 0.363 0.113 1.61 0.256 0.0214 0.36 1.3941 0.8438 1438389 ChemDiv3_013810 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D17 compound treatment 0.352 0.102 1.46 0.28 0.0454 0.76 1.5676 0.9544 3120269 ChemDiv3_013811 COc1cccc(c1)C2C=C(Nc3ncnn23)c4cccc(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D18 compound treatment 0.411 0.161 2.3 0.279 0.0444 0.74 2.1525 0.8906 1315940 ChemDiv3_013812 Cc1n[nH]c2nc(SCC(=O)NCC3CCCO3)n(c4ccc(C)c(Cl)c4)c(=N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D19 compound treatment 0.415 0.165 2.36 0.249 0.0144 0.24 1.8369 0.7754 1259774 ChemDiv3_013813 CCOC(=O)C1=C(C)Nc2ncnn2C1c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D20 compound treatment 0.406 0.156 2.23 0.272 0.0374 0.63 2.0189 0.8723 3038770 ChemDiv3_013814 O=C(Cn1c(=O)oc2ccccc12)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D21 compound treatment 0.404 0.154 2.2 0.257 0.0224 0.38 1.8206 0.816 1440355 ChemDiv3_013815 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(O)cc3)C(=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D22 compound treatment 0.422 0.172 2.46 0.273 0.0384 0.64 2.1926 0.8633 3038837 ChemDiv3_013816 Cc1ccc(cc1)S(=O)(=O)CCC(=O)Nc2ccc(C)c(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D23 mock treatment 0.281 0.0308 0.44 0.256 0.0214 0.36 0.5647 0.9949 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 D24 mock treatment 0.251 7.5E-4 0.01 0.235 3.75E-4 0.01 0.012 0.9677 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E01 compound treatment 0.226 -0.0243 -0.35 0.246 0.0114 0.19 -0.1103 -0.2785 3038838 ChemDiv3_013817 CN(Cc1ccco1)C(=O)c2ccc3Sc4ccccc4C(=O)N(Cc5cccc(F)c5)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E02 compound treatment 0.241 -0.00925 -0.13 0.217 -0.0176 -0.3 -0.3027 -0.9342 3038839 ChemDiv3_013818 CC(N1CCC(CNC(=O)Nc2ccc(Cl)cc2)C1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E03 compound treatment 0.323 0.0727 1.04 0.257 0.0224 0.38 1.0014 0.9052 3120270 ChemDiv3_013819 CC1CCN(CCCNC(=O)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E04 compound treatment 0.358 0.108 1.54 0.266 0.0314 0.53 1.4622 0.8978 3038842 ChemDiv3_013820 CC(CCc1ccccc1)NC(=O)c2cc3c(C)nccc3[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E05 compound treatment 0.335 0.0848 1.21 0.255 0.0204 0.34 1.099 0.8725 3120271 ChemDiv3_013821 Cc1cccc(N2CCN(CC2)C(=O)CN3C(=O)/C(=C\c4cccc(F)c4)/Oc5ccccc35)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E06 compound treatment 0.444 0.194 2.77 0.224 -0.0106 -0.18 1.8335 0.6602 3038844 ChemDiv3_013822 Cc1ccccc1CN2C(=O)/C(=C\c3ccc(cc3)C(=O)N4CCOCC4)/Sc5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E07 compound treatment 0.263 0.0127 0.18 0.192 -0.0426 -0.72 -0.3769 -0.5105 3120272 ChemDiv3_013823 CC1CC(C)CN(C1)C(=O)c2cc(Nc3cccc(c3)C(F)(F)F)nc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E08 compound treatment 0.327 0.0767 1.1 0.28 0.0454 0.76 1.3148 0.984 3120273 ChemDiv3_013824 Clc1ccccc1c2cc(=O)n(CC(=O)NCc3cccs3)c4CCCc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E09 compound treatment 0.348 0.0978 1.4 0.249 0.0144 0.24 1.1593 0.817 3038846 ChemDiv3_013825 Cn1cc(CN(Cc2ccccc2)C(=O)Nc3ccccc3)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E10 compound treatment 0.382 0.132 1.88 0.268 0.0334 0.56 1.7286 0.8793 3120274 ChemDiv3_013826 Cc1oc(nc1CS(=O)CC(=O)Nc2ccc(C)cc2)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E11 compound treatment 0.336 0.0858 1.23 0.275 0.0404 0.68 1.3465 0.9609 3038848 ChemDiv3_013827 O=C(CCN1N=C(CCC1=O)c2ccccc2)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E12 compound treatment 0.344 0.0938 1.34 0.257 0.0224 0.38 1.2138 0.8716 1567917 ChemDiv3_013828 COc1ccc(cc1)C2=NN3C(C2)c4cccc(OC)c4OC3(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E13 compound treatment 0.382 0.132 1.88 0.287 0.0524 0.88 1.9541 0.9397 3120275 ChemDiv3_013829 CCN(CC)C(=O)c1ccc2S/C(=C\c3ccccc3)/C(=O)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E14 compound treatment 0.413 0.163 2.33 0.252 0.0174 0.29 1.8523 0.7895 3038850 ChemDiv3_013830 Ic1ccccc1NC(=O)CC2CC3CCC2C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E15 compound treatment 0.386 0.136 1.94 0.288 0.0534 0.9 2.0065 0.9383 3120276 ChemDiv3_013831 Cc1ccc(cc1N2CCCC2=O)C(=O)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E16 compound treatment 0.421 0.171 2.44 0.283 0.0484 0.81 2.3011 0.8941 3038853 ChemDiv3_013832 CC(CCc1ccccc1)NC(=O)c2ccc3ccccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E17 compound treatment 0.398 0.148 2.11 0.299 0.0644 1.08 2.2584 0.9515 3120277 ChemDiv3_013833 CCCN(CCC)C(=O)c1ccc2S(=O)c3ccccc3C(=O)N(Cc4ccccc4C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E18 compound treatment 0.439 0.189 2.7 0.276 0.0414 0.69 2.4001 0.861 3038854 ChemDiv3_013834 CSc1ncccc1C(=O)NCc2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E19 compound treatment 0.358 0.108 1.54 0.231 -0.00362 -0.06 1.0468 0.6787 3120278 ChemDiv3_013835 CC1CCCC(NC(=O)c2cc(C)nn2c3ccccc3)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E20 compound treatment 0.371 0.121 1.73 0.28 0.0454 0.76 1.7598 0.9323 3038856 ChemDiv3_013836 Fc1ccc(CNC(=O)Cc2cccc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E21 compound treatment 0.402 0.152 2.17 0.278 0.0434 0.73 2.0496 0.8953 3120279 ChemDiv3_013837 OC(=O)CNC(=O)/C=C/c1ccccc1F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E22 compound treatment 0.413 0.163 2.33 0.251 0.0164 0.27 1.8404 0.7851 3120280 ChemDiv3_013838 Cc1ccc(cc1)C(=O)CCC(=O)Nc2ccc(Br)c(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E23 mock treatment 0.272 0.0217 0.31 0.242 0.00737 0.12 0.3075 0.9184 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 E24 mock treatment 0.224 -0.0262 -0.38 0.229 -0.00562 -0.09 -0.3323 -0.8582 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F01 compound treatment 0.264 0.0138 0.2 0.259 0.0244 0.41 0.4284 0.9437 3038914 ChemDiv3_013839 Brc1ccc2nc(NC(=O)CCCC(=O)c3ccccc3)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F02 compound treatment 0.249 -0.00125 -0.02 0.224 -0.0106 -0.18 -0.1387 -0.7741 1660423 ChemDiv3_013840 CCNC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F03 compound treatment 0.256 0.00575 0.08 0.238 0.00337 0.06 0.0982 0.9834 3038916 ChemDiv3_013841 O=C(NC(c1ccccc1)c2ccccc2)/C=C/c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F04 compound treatment 0.297 0.0468 0.67 0.174 -0.0606 -1.02 -0.2467 -0.2026 1410790 ChemDiv3_013842 CC1CC(C)CN(C1)c2ncnc3scc(c4ccccc4)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F05 compound treatment 0.349 0.0988 1.41 0.244 0.00937 0.16 1.11 0.781 3038918 ChemDiv3_013843 O=C(CN1C(=O)c2ccccc2C1=O)NC3=NCCS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F06 compound treatment 0.356 0.106 1.51 0.279 0.0444 0.74 1.5962 0.9467 1203378 ChemDiv3_013844 CCCn1c(=O)c(C(=O)NCCc2ccccc2)c(O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F07 compound treatment 0.412 0.162 2.31 0.28 0.0454 0.76 2.1745 0.8927 1167902 ChemDiv3_013845 CCOC(=O)c1sc2nc(Cc3ccccc3)nc(NCCC4=CCCCC4)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F08 compound treatment 0.447 0.197 2.81 0.317 0.0824 1.38 2.9676 0.9464 1247758 ChemDiv3_013846 Clc1ccccc1CSc2ncccc2C(=O)NCCC3=CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F09 compound treatment 0.396 0.146 2.08 0.295 0.0604 1.01 2.1907 0.9451 3038921 ChemDiv3_013847 CCCC(=O)c1c(O)c2ccccc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F10 compound treatment 0.418 0.168 2.4 0.304 0.0694 1.16 2.52 0.9449 3120281 ChemDiv3_013848 Cc1c(sc2nc(C)nc(N3CCCCC3)c12)C(=O)Nc4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F11 compound treatment 0.446 0.196 2.8 0.29 0.0554 0.93 2.6371 0.8939 3038923 ChemDiv3_013849 Cc1ccc(cc1)c2nc(no2)C3CCN(CC3)S(=O)(=O)c4ccc(cc4)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F12 compound treatment 0.424 0.174 2.49 0.207 -0.0276 -0.46 1.4295 0.5654 1271470 ChemDiv3_013850 CCOc1nc(NC2CCCCC2)nc(Nc3ccc(I)cc3C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F13 compound treatment 0.458 0.208 2.97 0.331 0.0964 1.62 3.245 0.9591 1253344 ChemDiv3_013851 CC(C)CCNC(=O)c1sc2ncnc(N3CCOCC3)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F14 compound treatment 0.447 0.197 2.81 0.298 0.0634 1.06 2.7421 0.9114 1131974 ChemDiv3_013852 O=S(=O)(N1CCCCC1)c2cccc3nsnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F15 compound treatment 0.445 0.195 2.79 0.285 0.0504 0.85 2.5676 0.882 1344022 ChemDiv3_013853 CC(C)CCNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F16 compound treatment 0.444 0.194 2.77 0.319 0.0844 1.42 2.961 0.9514 1414503 ChemDiv3_013854 COC(CNC(=O)c1ccc2n(cnc2c1)c3ccc(F)cc3F)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F17 compound treatment 0.38 0.13 1.86 0.288 0.0534 0.9 1.9458 0.9442 3120282 ChemDiv3_013855 CCc1ccc(cc1)C2=CC(c3ccc(SC)cc3)n4nnnc4N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F18 compound treatment 0.409 0.159 2.27 0.288 0.0534 0.9 2.2391 0.9173 1418586 ChemDiv3_013856 COc1ccccc1NC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2c4ccc(C)c(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F19 compound treatment 0.238 -0.0123 -0.18 0.117 -0.118 -1.97 -1.5199 -0.7669 3039096 ChemDiv3_013857 Fc1ccccc1/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccccc5F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F20 compound treatment 0.407 0.157 2.24 0.264 0.0294 0.49 1.934 0.8425 3039097 ChemDiv3_013858 Cc1cc2c(=O)n(CC(=O)Nc3ccc(F)cc3F)cnc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F21 compound treatment 0.393 0.143 2.04 0.29 0.0554 0.93 2.101 0.9365 3039098 ChemDiv3_013859 COC(=O)C1=CN(C)C=C(C1c2ccc(cc2)C(C)C)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F22 compound treatment 0.345 0.0948 1.36 0.248 0.0134 0.22 1.1171 0.8132 3039099 ChemDiv3_013860 O=C(Nc1ccc2OCOc2c1)C3CCC(CNC(=O)c4ccc(=O)[nH]c4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F23 mock treatment 0.262 0.0118 0.17 0.253 0.0184 0.31 0.3369 0.9593 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 F24 mock treatment 0.226 -0.0243 -0.35 0.233 -0.00162 -0.03 -0.2646 -0.7604 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G01 compound treatment 0.261 0.0107 0.15 0.226 -0.00862 -0.14 0.0064 0.0301 3039100 ChemDiv3_013861 Clc1cccc(CSCc2ccc(o2)C(=O)NCc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G02 compound treatment 0.238 -0.0123 -0.18 0.232 -0.00262 -0.04 -0.1551 -0.8582 3039101 ChemDiv3_013862 CC(N1CCC(CNC(=S)Nc2ccc(C)cc2)C1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G03 compound treatment 0.27 0.0198 0.28 0.229 -0.00562 -0.09 0.133 0.4465 3120283 ChemDiv3_013863 O=C(NC1CCCCC1)c2ccc(/C=C/3\Oc4ccccc4NC3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G04 compound treatment 0.355 0.105 1.5 0.262 0.0274 0.46 1.3844 0.8833 3039102 ChemDiv3_013864 Cc1ccc(CCNC(=O)c2cc3c(C)nccc3[nH]c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G05 compound treatment 0.355 0.105 1.5 0.267 0.0324 0.54 1.4437 0.9058 3120284 ChemDiv3_013865 CCOc1ccc(Nc2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G06 compound treatment 0.4 0.15 2.14 0.269 0.0344 0.58 1.9226 0.8667 3120285 ChemDiv3_013866 Cc1ccccc1CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NCc4ccco4)/Sc5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G07 compound treatment 0.307 0.0568 0.81 0.276 0.0414 0.69 1.065 0.997 3039103 ChemDiv3_013867 O=C(CCN1N=C(CCC1=O)c2ccccc2)NCCCN3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G08 compound treatment 0.277 0.0268 0.38 0.192 -0.0426 -0.72 -0.2353 -0.2901 3120286 ChemDiv3_013868 Cc1ccc(cc1)c2nn(CC(=O)NC3CCCc4ccccc34)c(=O)c5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G09 compound treatment 0.397 0.147 2.1 0.304 0.0694 1.16 2.3076 0.9613 3039104 ChemDiv3_013869 Fc1ccc(CN2CCCN(CC(=O)NC3CCCCCC3)C2=O)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G10 compound treatment 0.409 0.159 2.27 0.308 0.0734 1.23 2.4765 0.9587 3120287 ChemDiv3_013870 Fc1cc(Br)ccc1NC(=O)CSCCc2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G11 compound treatment 0.372 0.122 1.74 0.235 3.75E-4 0.01 1.2359 0.7097 3120288 ChemDiv3_013871 O=C(CN1C(=O)/C(=C\c2ccccc2)/Oc3ccccc13)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G12 compound treatment 0.39 0.14 2.0 0.291 0.0564 0.95 2.0825 0.9417 3039105 ChemDiv3_013872 OCc1nc2cc(ccc2[nH]1)S(=O)(=O)c3ccc4[nH]c(CO)nc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G13 compound treatment 0.386 0.136 1.94 0.29 0.0554 0.93 2.0302 0.9431 3120467 ChemDiv3_013873 Cc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)n3ccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G14 compound treatment 0.334 0.0838 1.2 0.295 0.0604 1.01 1.5636 0.9965 3039106 ChemDiv3_013874 CC(=O)Nc1ccc(NC(=O)CCCc2c[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G15 compound treatment 0.333 0.0828 1.18 0.273 0.0384 0.64 1.2924 0.9591 3120468 ChemDiv3_013875 O=C(NCc1ccccc1)c2ccc3S/C(=C\c4ccccc4)/C(=O)Nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G16 compound treatment 0.398 0.148 2.11 0.309 0.0744 1.25 2.3771 0.9684 3120469 ChemDiv3_013876 Oc1ccc(CCNC(=O)c2ccc3ccccc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G17 compound treatment 0.351 0.101 1.44 0.295 0.0604 1.01 1.7355 0.9852 3039107 ChemDiv3_013877 COc1ccc(/C=C\2/Sc3ccc(cc3NC2=O)C(=O)N(C)C4CCCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G18 compound treatment 0.371 0.121 1.73 0.328 0.0934 1.57 2.3295 0.9988 3120470 ChemDiv3_013878 COc1ccc(NC(=O)c2cccnc2SC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G19 compound treatment 0.326 0.0757 1.08 0.248 0.0134 0.22 0.9249 0.8359 3120471 ChemDiv3_013879 CCOc1ccc(NC(=O)N(CCc2ccncc2)C(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G20 compound treatment 0.341 0.0908 1.3 0.26 0.0254 0.43 1.219 0.8923 1408397 ChemDiv3_013880 COc1ccc(NC(=O)Cc2cccc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G21 compound treatment 0.373 0.123 1.76 0.188 -0.0466 -0.78 0.6882 0.358 3120472 ChemDiv3_013881 Cc1ccc(cc1)C2CCN(C2)C(=S)Nc3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G22 compound treatment 0.324 0.0737 1.05 0.259 0.0244 0.41 1.0352 0.9149 3039108 ChemDiv3_013882 Cc1ccc(cc1)C(=O)CCC(=O)Nc2cccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G23 mock treatment 0.263 0.0127 0.18 0.238 0.00337 0.06 0.169 0.885 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 G24 mock treatment 0.251 7.5E-4 0.01 0.219 -0.0156 -0.26 -0.1779 -0.6776 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H01 compound treatment 0.289 0.0388 0.55 0.246 0.0114 0.19 0.5269 0.8988 3120473 ChemDiv3_013883 Oc1ccc(NC(=O)CCCC(=O)c2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H02 compound treatment 0.286 0.0357 0.51 0.252 0.0174 0.29 0.5678 0.9645 1419333 ChemDiv3_013884 CNC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)N3CCC(C)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H03 compound treatment 0.296 0.0457 0.65 0.261 0.0264 0.44 0.7757 0.9819 3039109 ChemDiv3_013885 FC(F)(F)c1ccccc1CNC(=O)/C=C/c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H04 compound treatment 0.075 -0.175 -2.51 0.056 -0.179 -3.0 -3.8925 -0.996 1637040 ChemDiv3_013886 CCN(CC)c1nc(nc2ccccc12)c3ccccc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H05 compound treatment 0.385 0.135 1.93 0.252 0.0174 0.29 1.5691 0.8049 3120474 ChemDiv3_013887 CC1(CC2CC(C)(C)C1)CN2C(=O)CN3C(=O)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H06 compound treatment 0.144 -0.106 -1.52 0.054 -0.181 -3.03 -3.2183 -0.949 1451213 ChemDiv3_013888 CCc1nc2ccccc2c(=O)n1NC(=O)c3c(O)c4ccccc4n(CC)c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H07 compound treatment 0.349 0.0988 1.41 0.257 0.0224 0.38 1.2643 0.8651 1557141 ChemDiv3_013889 Clc1ccccc1N2C(=O)C(Cc3c[nH]c4ccccc34)NC2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H08 compound treatment 0.416 0.166 2.37 0.297 0.0624 1.05 2.4167 0.9325 1415454 ChemDiv3_013890 COc1ccc(NC(=O)Cc2nn(C)c(=O)c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H09 compound treatment 0.407 0.157 2.24 0.269 0.0344 0.58 1.9934 0.861 3039110 ChemDiv3_013891 CN1/C(=C\C(=O)C2CCCCC2)/C(C)(C)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H10 compound treatment 0.354 0.104 1.48 0.256 0.0214 0.36 1.303 0.8535 3120475 ChemDiv3_013892 CC1CCCCN1c2ncnc3sc(C(=O)NCCC4=CCCCC4)c(C)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H11 compound treatment 0.422 0.172 2.46 0.319 0.0844 1.42 2.7385 0.9658 3039111 ChemDiv3_013893 COC(=O)c1cc(nc2ccc(C)cc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H12 compound treatment 0.379 0.129 1.84 0.328 0.0934 1.57 2.4104 0.9968 3120476 ChemDiv3_013894 CCN(CC)C(=O)c1sc2ncn(CC(=O)Nc3cccc(c3)C(F)(F)F)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H13 compound treatment 0.362 0.112 1.6 0.286 0.0514 0.86 1.74 0.958 3120477 ChemDiv3_013895 OC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H14 compound treatment 0.372 0.122 1.74 0.269 0.0344 0.58 1.6394 0.8936 3039112 ChemDiv3_013896 Brc1cc(sc1Br)S(=O)(=O)NCCCN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H15 compound treatment 0.359 0.109 1.56 0.277 0.0424 0.71 1.6028 0.9371 1357362 ChemDiv3_013897 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCCC4=CCCCC4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H16 compound treatment 0.401 0.151 2.16 0.282 0.0474 0.8 2.087 0.9081 1534773 ChemDiv3_013898 CCCNC(=O)c1ccc2n(cnc2c1)c3cc(OC)ccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H17 compound treatment 0.425 0.175 2.5 0.308 0.0734 1.23 2.6383 0.9468 3120478 ChemDiv3_013899 COc1cc(OC)c(cc1OC)C2C3=C(CC(C)(C)CC3=O)Nc4nc5ccccc5n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H18 compound treatment 0.298 0.0478 0.68 0.292 0.0574 0.96 1.1639 0.9858 1703943 ChemDiv3_013900 CCC(C)NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H19 compound treatment 0.127 -0.123 -1.76 0.063 -0.172 -2.88 -3.2834 -0.9722 1865647 ChemDiv3_013901 COc1ccc(/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccc(OC)cc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H20 compound treatment 0.38 0.13 1.86 0.299 0.0644 1.08 2.0763 0.9669 1356163 ChemDiv3_013902 COc1ccc(cc1OC)C(=O)NCC2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H21 compound treatment 0.347 0.0968 1.38 0.252 0.0174 0.29 1.1848 0.8377 3120480 ChemDiv3_013903 CCOC(=O)C1=CN(Cc2ccc(F)cc2)C=C(C1c3ccc(cc3)C(F)(F)F)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H22 compound treatment 0.347 0.0968 1.38 0.288 0.0534 0.9 1.612 0.9778 3039113 ChemDiv3_013904 Brc1ccc(NC(=O)CNC(=O)c2ccco2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H23 mock treatment 0.242 -0.00825 -0.12 0.232 -0.00262 -0.04 -0.1146 -0.9098 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 H24 mock treatment 0.25 -2.5E-4 0.0 0.216 -0.0186 -0.31 -0.2236 -0.7151 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I01 compound treatment 0.246 -0.00425 -0.06 0.265 0.0304 0.51 0.3175 0.6184 3120481 ChemDiv3_013905 Clc1cccc(CSCc2ccc(o2)C(=O)NC3CCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I02 compound treatment 0.268 0.0177 0.25 0.275 0.0404 0.68 0.6587 0.9102 3120482 ChemDiv3_013906 CCN1CCN(CCNC(=O)c2ccc3S/C(=C/c4cccc(Cl)c4)/C(=O)Nc3c2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I03 compound treatment 0.274 0.0238 0.34 0.231 -0.00362 -0.06 0.1972 0.5714 3039114 ChemDiv3_013907 CCC(C)NC(=O)c1ccc(/C=C\2/Sc3ccccc3NC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I04 compound treatment 0.337 0.0867 1.24 0.293 0.0584 0.98 1.5702 0.9932 3120483 ChemDiv3_013908 Cc1nccc2[nH]c(=O)c(cc12)C(=O)NCCCN3CCC(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I05 compound treatment 0.356 0.106 1.51 0.229 -0.00562 -0.09 1.0028 0.6617 3039115 ChemDiv3_013909 Fc1ccccc1CN2CCCN(C2)C(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I06 compound treatment 0.347 0.0968 1.38 0.236 0.00137 0.02 0.9949 0.7188 3120484 ChemDiv3_013910 Clc1ccccc1c2cc(=O)n(CC(=O)NC3CC3)c4CCCc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I07 compound treatment 0.398 0.148 2.11 0.301 0.0664 1.11 2.2821 0.9553 3039116 ChemDiv3_013911 O=C(c1ccc(cc1)N2CCCC2=O)n3ccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I08 compound treatment 0.375 0.125 1.78 0.286 0.0514 0.86 1.8715 0.9443 3120485 ChemDiv3_013912 CC1N=C(c2ccccc2F)c3cc(Cl)ccc3N(Cc4nc(oc4C)c5cccc(C)c5)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I09 compound treatment 0.379 0.129 1.84 0.211 -0.0236 -0.4 1.0218 0.5424 3120486 ChemDiv3_013913 CCOC(=O)c1ccc(NC(=S)N2CCCN(Cc3cc(C)ccc3C)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I10 compound treatment 0.354 0.104 1.48 0.283 0.0484 0.81 1.6235 0.9597 3039117 ChemDiv3_013914 O=C(CSCCc1ccccn1)Nc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I11 compound treatment 0.367 0.117 1.67 0.233 -0.00162 -0.03 1.1616 0.6955 3120487 ChemDiv3_013915 O=C(CN1C(=O)/C(=C\c2ccccc2)/Oc3ccccc13)NCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I12 compound treatment 0.326 0.0757 1.08 0.31 0.0754 1.27 1.6607 0.997 3039118 ChemDiv3_013916 O=C(CC1CC2CCC1C2)NC(c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I13 compound treatment 0.362 0.112 1.6 0.259 0.0244 0.41 1.4195 0.8604 3120488 ChemDiv3_013917 Cc1nn2c(cc(C)nc2c1c3ccc(Cl)cc3)N4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I14 compound treatment 0.338 0.0878 1.26 0.227 -0.00762 -0.13 0.797 0.6317 3039119 ChemDiv3_013918 O=C(CCCc1c[nH]c2ccccc12)NC3=NCCS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I15 compound treatment 0.462 0.212 3.03 0.285 0.0504 0.85 2.7395 0.8712 3120489 ChemDiv3_013919 O=C(NC1CC1)c2ccc3S/C(=C\c4ccccc4)/C(=O)Nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I16 compound treatment 0.377 0.127 1.81 0.258 0.0234 0.39 1.5594 0.8407 3120658 ChemDiv3_013920 COc1cc(CCC(=O)NC2CCCCC2)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I17 compound treatment 0.337 0.0867 1.24 0.279 0.0444 0.74 1.4041 0.9702 3039120 ChemDiv3_013921 COc1ccc(OC)c(/C=C\C(=O)NCC(=O)O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I18 compound treatment 0.323 0.0727 1.04 0.276 0.0414 0.69 1.2269 0.9807 3120659 ChemDiv3_013922 COc1ccc(NC(=O)c2ccc(C)c(I)c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I19 compound treatment 0.314 0.0638 0.91 0.274 0.0394 0.66 1.1121 0.9875 3039121 ChemDiv3_013923 CC(C)N(CCc1ccncc1)C(=O)Nc2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I20 compound treatment 0.433 0.183 2.61 0.261 0.0264 0.44 2.1614 0.8152 3120660 ChemDiv3_013924 O=C(Cc1cccc2ccccc12)Nc3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I21 compound treatment 0.305 0.0548 0.78 0.243 0.00837 0.14 0.6531 0.8209 3039122 ChemDiv3_013925 CC(C)NC(=S)N1CCC(C1)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I22 compound treatment 0.415 0.165 2.36 0.259 0.0244 0.41 1.9556 0.8176 3120661 ChemDiv3_013926 Clc1ccc(NC(=O)CCCC(=O)c2ccccc2)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I23 mock treatment 0.244 -0.00625 -0.09 0.234 -6.25E-4 -0.01 -0.0706 -0.7847 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 I24 mock treatment 0.25 -2.5E-4 0.0 0.232 -0.00262 -0.04 -0.0337 -0.762 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J01 compound treatment 0.278 0.0278 0.4 0.243 0.00837 0.14 0.3801 0.9026 3120662 ChemDiv3_013927 CC(=O)Nc1ccc(NC(=O)CCC(=O)c2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J02 compound treatment 0.252 0.00175 0.03 0.293 0.0584 0.98 0.7105 0.7249 1226624 ChemDiv3_013928 O=C(Nc1ccccc1C(=O)N2CCCCCC2)c3cccc(c3)S(=O)(=O)N4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J03 compound treatment 0.291 0.0408 0.58 0.245 0.0104 0.17 0.5353 0.8799 3039123 ChemDiv3_013929 Cc1nn(C)c(C)c1NC(=O)/C=C/c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J04 compound treatment 0.343 0.0928 1.33 0.265 0.0304 0.51 1.2986 0.9137 3039124 ChemDiv3_013930 COc1ccc(cc1)c2cn(c3SCC[n+]23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J05 compound treatment 0.357 0.107 1.53 0.239 0.00437 0.07 1.1316 0.7403 1657713 ChemDiv3_013931 O=C(CN1C(=O)c2ccccc2C1=O)NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J06 compound treatment 0.431 0.181 2.59 0.285 0.0504 0.85 2.426 0.8919 1499484 ChemDiv3_013932 CCNC(=O)c1c(O)c2cccc3CCn(c1=O)c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J07 compound treatment 0.401 0.151 2.16 0.286 0.0514 0.86 2.1344 0.9191 3039345 ChemDiv3_013933 COC(=O)C1=CN(Cc2ccc(C)cc2)C=C(C1c3ccc(C)s3)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J08 compound treatment 0.373 0.123 1.76 0.273 0.0384 0.64 1.697 0.9074 1267708 ChemDiv3_013934 COc1ccc(cc1)N2CCN(CC2)C(=O)Cc3nn(C)c(=O)c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J09 compound treatment 0.471 0.221 3.16 0.305 0.0704 1.18 3.0679 0.91 3039347 ChemDiv3_013935 CC(C)C(=O)c1c(O)c2ccccc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J10 compound treatment 0.391 0.141 2.01 0.243 0.00837 0.14 1.523 0.7546 1267288 ChemDiv3_013936 COc1cc(OC)c(NC(=O)c2sc3ncnc(N4CCCCC4C)c3c2C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J11 compound treatment 0.5 0.25 3.57 0.252 0.0174 0.29 2.7322 0.7623 3039349 ChemDiv3_013937 Oc1nc(CSCC(=O)NC2CCCCCC2)nc3n(Cc4ccc(F)cc4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J12 compound treatment 0.444 0.194 2.77 0.282 0.0474 0.8 2.5219 0.8747 1131500 ChemDiv3_013938 CCN(CC)c1ncnc2sc(C(=O)N(C)C3CCCCC3)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J13 compound treatment 0.373 0.123 1.76 0.274 0.0394 0.66 1.7088 0.9109 1144209 ChemDiv3_013939 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCCC4=CCCCC4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J14 compound treatment 0.43 0.18 2.57 0.34 0.105 1.77 3.0686 0.9833 1118892 ChemDiv3_013940 COc1ccccc1n2cnc3cc(ccc23)C(=O)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J15 compound treatment 0.37 0.12 1.71 0.254 0.0194 0.33 1.4411 0.8266 1196467 ChemDiv3_013941 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NC4CCCCC4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J16 compound treatment 0.444 0.194 2.77 0.268 0.0334 0.56 2.3557 0.8332 1134270 ChemDiv3_013942 CCCNC(=O)c1ccc2n(cnc2c1)c3ccc(OCc4ccccc4)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J17 compound treatment 0.376 0.126 1.8 0.29 0.0554 0.93 1.9291 0.9528 3120663 ChemDiv3_013943 COc1ccc(cc1)C2C3=C(CCCC3=O)Nc4nc5ccccc5n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J18 compound treatment 0.311 0.0607 0.87 0.26 0.0254 0.43 0.9156 0.9461 1702176 ChemDiv3_013944 Cc1n[nH]c2nc(SCC(=O)N3CCCC3)n(c4ccc(Br)cc4)c(=N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J19 compound treatment 0.145 -0.105 -1.51 0.063 -0.172 -2.88 -3.1014 -0.9542 1865902 ChemDiv3_013945 Cc1ccc(/C=C/2\CCCC3=C2Nc4nnnn4C3c5ccc(C)cc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J20 compound treatment 0.397 0.147 2.1 0.281 0.0464 0.78 2.0346 0.9088 1118565 ChemDiv3_013946 O=C(Oc1ccc2sc(=O)oc2c1)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J21 compound treatment 0.345 0.0948 1.36 0.271 0.0364 0.61 1.39 0.9351 3120665 ChemDiv3_013947 CCOC(=O)C1=CN(C)C=C(C1c2cc(Br)c(O)c(OC)c2)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J22 compound treatment 0.392 0.142 2.03 0.239 0.00437 0.07 1.4856 0.7322 3039356 ChemDiv3_013948 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)C3(CC3)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J23 mock treatment 0.261 0.0107 0.15 0.252 0.0174 0.29 0.3149 0.9553 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 J24 mock treatment 0.261 0.0107 0.15 0.248 0.0134 0.22 0.2675 0.983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K01 compound treatment 0.281 0.0308 0.44 0.249 0.0144 0.24 0.4816 0.96 3120666 ChemDiv3_013949 COC(CNC(=O)c1ccc(CS(=O)(=O)Cc2ccc(Cl)cc2)o1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K02 compound treatment 0.259 0.00875 0.13 0.227 -0.00762 -0.13 -0.002 -0.0111 3120667 ChemDiv3_013950 COC(CNC(=O)c1ccc(/C=C\2/Sc3ccccc3N(Cc4cccc(C)c4)C2=O)cc1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K03 compound treatment 0.292 0.0418 0.6 0.27 0.0354 0.59 0.8421 1.0 3039359 ChemDiv3_013951 CC(=O)N1CCC(CC1)N(CCN2CCOCC2)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K04 compound treatment 0.362 0.112 1.6 0.272 0.0374 0.63 1.5738 0.9166 3120668 ChemDiv3_013952 CC1CCC(CC1)NC(=O)c2cc3c(C)nccc3[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K05 compound treatment 0.408 0.158 2.26 0.255 0.0204 0.34 1.8373 0.8051 3039361 ChemDiv3_013953 CCCCN(C1CCN(CC1)C(=O)C)C(=S)Nc2ccccc2CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K06 compound treatment 0.35 0.0998 1.43 0.273 0.0384 0.64 1.4643 0.9354 3039415 ChemDiv3_013954 CCCNC(=O)Cn1c2CCCc2c(cc1=O)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K07 compound treatment 0.291 0.0408 0.58 0.225 -0.00962 -0.16 0.2979 0.4926 3039416 ChemDiv3_013955 Cc1ccc(CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NCc4cccnc4)/Oc5ccccc25)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K08 compound treatment 0.334 0.0838 1.2 0.283 0.0484 0.81 1.4212 0.9821 3039418 ChemDiv3_013956 CCCNC(=O)c1ccc(CS(=O)(=O)c2ccc(OC)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K09 compound treatment 0.379 0.129 1.84 0.304 0.0694 1.16 2.1256 0.9755 3039419 ChemDiv3_013957 CC(C)CCNC(=O)c1ccc(CS(=O)(=O)Cc2ccc(F)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K10 compound treatment 0.427 0.177 2.53 0.232 -0.00262 -0.04 1.7565 0.6947 3039421 ChemDiv3_013958 COc1ccccc1NC(=O)c2c(NCc3sccc3C)sc4CCCCc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K11 compound treatment 0.417 0.167 2.39 0.266 0.0314 0.53 2.0589 0.8429 3039422 ChemDiv3_013959 Brc1ccccc1/C=C\2/Oc3ccccc3N(CC(=O)NC4CC4)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K12 compound treatment 0.32 0.0698 1.0 0.134 -0.101 -1.69 -0.4888 -0.2492 3120669 ChemDiv3_013960 Cc1cccc(NC(=O)CC2CC3CCC2C3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K13 compound treatment 0.374 0.124 1.77 0.285 0.0504 0.85 1.8495 0.9428 3120670 ChemDiv3_013961 CCC(C)NC(=O)CCN1N=C(CCC1=O)c2ccc(CC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K14 compound treatment 0.389 0.139 1.98 0.301 0.0664 1.11 2.1911 0.9627 3039425 ChemDiv3_013962 FC(F)(F)c1ccccc1CNC(=O)CCCc2c[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K15 compound treatment 0.452 0.202 2.89 0.287 0.0524 0.88 2.6621 0.8825 3120671 ChemDiv3_013963 OC(=O)CNC(=O)/C=C/c1cccc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K16 compound treatment 0.401 0.151 2.16 0.263 0.0284 0.48 1.8615 0.843 3039427 ChemDiv3_013964 COc1cc(CCC(=O)NCc2ccccc2)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K17 compound treatment 0.426 0.176 2.51 0.296 0.0614 1.03 2.506 0.9224 3120672 ChemDiv3_013965 COC(CNC(=O)c1ccc2S/C(=C/c3cccc(OC)c3)/C(=O)Nc2c1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K18 compound treatment 0.361 0.111 1.58 0.312 0.0774 1.3 2.0384 0.9951 3039429 ChemDiv3_013966 Cc1ccc(cc1I)C(=O)Nc2ccc(Br)cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K19 compound treatment 0.465 0.215 3.07 0.255 0.0204 0.34 2.4138 0.781 3120673 ChemDiv3_013967 CC(C)N(CCc1ccncc1)C(=S)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K20 compound treatment 0.396 0.146 2.08 0.235 3.75E-4 0.01 1.4786 0.7092 3120674 ChemDiv3_013968 COc1ccc(C(=O)N(CCc2ccccc2)Cc3ccccc3)c(OC)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K21 compound treatment 0.431 0.181 2.59 0.203 -0.0316 -0.53 1.4528 0.5505 3039431 ChemDiv3_013969 Cc1ccc(cc1)C2CCN(C2)C(=S)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K22 compound treatment 0.443 0.193 2.76 0.253 0.0184 0.31 2.1676 0.7813 3120675 ChemDiv3_013970 O=C(CCCC(=O)c1ccccc1)Nc2ccc3CCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K23 mock treatment 0.268 0.0177 0.25 0.25 0.0154 0.26 0.362 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 K24 mock treatment 0.237 -0.0133 -0.19 0.246 0.0114 0.19 0.001 0.0037 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L01 compound treatment 0.259 0.00875 0.13 0.243 0.00837 0.14 0.1879 0.9983 3039434 ChemDiv3_013971 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L02 compound treatment 0.292 0.0418 0.6 0.26 0.0254 0.43 0.7234 0.9863 1182957 ChemDiv3_013972 CCN(CC)C(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)N(CC)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L03 compound treatment 0.274 0.0238 0.34 0.252 0.0174 0.29 0.4464 0.9971 3039436 ChemDiv3_013973 O=C(NCc1ccco1)/C=C/c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L04 compound treatment 0.405 0.155 2.21 0.279 0.0444 0.74 2.0918 0.8957 1123777 ChemDiv3_013974 CCCn1c(=O)c(C(=O)NC2(CC3CC4CC(C3)C2)C4)c(O)c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L05 compound treatment 0.401 0.151 2.16 0.275 0.0404 0.68 2.0039 0.8866 3039438 ChemDiv3_013975 O=C(NC1=NCCS1)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L06 compound treatment 0.314 0.0638 0.91 0.282 0.0474 0.8 1.207 0.9977 3120676 ChemDiv3_013976 NNC(=O)c1c(O)c2CCCCc2[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L07 compound treatment 0.317 0.0668 0.95 0.272 0.0374 0.63 1.1187 0.9792 1158928 ChemDiv3_013977 CCOC(=O)C1=C(C)N(C)C(=C(C1c2ccccc2F)C(=O)OCC)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L08 compound treatment 0.344 0.0938 1.34 0.262 0.0274 0.46 1.2731 0.8981 1153961 ChemDiv3_013978 CCn1c(=O)n(CC(=O)N(C)Cc2ccccc2)c(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L09 compound treatment 0.285 0.0348 0.5 0.058 -0.177 -2.96 -1.7447 -0.5804 3039500 ChemDiv3_013979 Oc1c(C(=O)CC2CCCCC2)c(=O)oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L10 compound treatment 0.381 0.131 1.87 0.357 0.122 2.05 2.7748 0.9989 1480114 ChemDiv3_013980 CC1CCN(CC1)c2ncnc3sc(C(=O)Nc4ccc(F)cc4F)c(C)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L11 compound treatment 0.322 0.0717 1.03 0.222 -0.0126 -0.21 0.5759 0.5495 3039502 ChemDiv3_013981 Cc1ccc(cc1Cl)n2c(SCc3ccccc3)nnc2c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L12 compound treatment 0.382 0.132 1.88 0.276 0.0414 0.69 1.8236 0.908 1401832 ChemDiv3_013982 CCN(CC)c1nc(C)nc2sc(C(=O)Nc3cc(Cl)ccc3OC)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L13 compound treatment 0.397 0.147 2.1 0.249 0.0144 0.24 1.6549 0.7832 1393537 ChemDiv3_013983 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCC(C)CC4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L14 compound treatment 0.358 0.108 1.54 0.312 0.0774 1.3 2.0081 0.9964 1519772 ChemDiv3_013984 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NCc4ccccc4OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L15 compound treatment 0.41 0.16 2.29 0.264 0.0294 0.49 1.9644 0.8403 1284089 ChemDiv3_013985 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCC5(CC4)OCCO5)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L16 compound treatment 0.429 0.179 2.56 0.227 -0.00762 -0.13 1.7174 0.6709 1380751 ChemDiv3_013986 Fc1cccc(c1)n2cnc3cc(ccc23)C(=O)NCCC4=CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L17 compound treatment 0.456 0.206 2.94 0.316 0.0814 1.37 3.0468 0.9391 3120860 ChemDiv3_013987 Clc1cccc(c1)C2C3=C(CCCC3=O)Nc4nc5ccccc5n24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L18 compound treatment 0.414 0.164 2.34 0.268 0.0334 0.56 2.0523 0.8522 1653478 ChemDiv3_013988 Cc1n[nH]c2nc(SCc3cc(=O)n4ccccc4n3)n(c5cccc(Cl)c5C)c(=N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L19 compound treatment 0.357 0.107 1.53 0.265 0.0304 0.51 1.4402 0.8946 3120861 ChemDiv3_013989 CC(C)c1ccc(cc1)C2=CC(c3ccc(C)cc3)n4ncnc4N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L20 compound treatment 0.364 0.114 1.63 0.282 0.0474 0.8 1.7127 0.9458 3039508 ChemDiv3_013990 FC(F)(F)c1cccc(c1)C(=O)N2CC(=O)N(CCc3ccccc3)C(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L21 compound treatment 0.448 0.198 2.83 0.255 0.0204 0.34 2.2419 0.7869 3120862 ChemDiv3_013991 COC(=O)C1=CN(Cc2ccc(OC)cc2)C=C(C1c3ccc(OC)cc3)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L22 compound treatment 0.413 0.163 2.33 0.276 0.0414 0.69 2.1371 0.8797 3039510 ChemDiv3_013992 Cc1n[nH]c(C)c1S(=O)(=O)N2CCc3ccccc3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L23 mock treatment 0.271 0.0208 0.3 0.224 -0.0106 -0.18 0.0838 0.2419 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 L24 mock treatment 0.245 -0.00525 -0.08 0.229 -0.00562 -0.09 -0.1199 -0.9936 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M01 compound treatment 0.302 0.0517 0.74 0.258 0.0234 0.39 0.8008 0.9559 3120863 ChemDiv3_013993 CC(C)CCN(C1CCN(CC1)C(=O)C)C(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M02 compound treatment 0.295 0.0447 0.64 0.267 0.0324 0.54 0.8368 0.9967 3120864 ChemDiv3_013994 Cc1cccc(CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NCc4cccnc4)/Sc5ccccc25)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M03 compound treatment 0.383 0.133 1.9 0.252 0.0174 0.29 1.5489 0.8063 3039512 ChemDiv3_013995 COc1ccc(NC(=S)N2CCCN(Cc3ccc(F)cc3)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M04 compound treatment 0.437 0.187 2.67 0.29 0.0554 0.93 2.546 0.9002 3120865 ChemDiv3_013996 COc1ccc(/C=C\2/Oc3ccccc3N(CC(=O)NC4CCCc5ccccc45)C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M05 compound treatment 0.374 0.124 1.77 0.267 0.0324 0.54 1.6359 0.8835 3039514 ChemDiv3_013997 CCOc1ccc(NC(=O)N(CCN2CCOCC2)Cc3ccc4N(CC)CCCc4c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M06 compound treatment 0.354 0.104 1.48 0.268 0.0334 0.56 1.4454 0.9113 3120866 ChemDiv3_013998 CCOc1ccc(cc1)c2nc(CSCC(=O)NC3CCCC3)c(C)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M07 compound treatment 0.306 0.0558 0.8 0.278 0.0434 0.73 1.0786 0.999 3120867 ChemDiv3_013999 COC(CN(C)C(=O)c1cn(C)c2ccc(cc2c1=O)S(=O)(=O)N3CCOCC3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M08 compound treatment 0.349 0.0988 1.41 0.301 0.0664 1.11 1.7865 0.9931 3039575 ChemDiv3_014000 O=C(N1CCCC1)c2ccc3S/C(=C\c4ccccc4)/C(=O)Nc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M09 compound treatment 0.355 0.105 1.5 0.266 0.0314 0.53 1.4318 0.9016 3039577 ChemDiv3_014001 O=C(CC1Nc2ccccc2NC1=O)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M10 compound treatment 0.381 0.131 1.87 0.216 -0.0186 -0.31 1.1014 0.5809 3039578 ChemDiv3_014002 CCOC(=O)c1ccc(NC(=O)c2c(NCc3ccc(C)o3)sc4CCCCc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M11 compound treatment 0.354 0.104 1.48 0.173 -0.0616 -1.03 0.318 0.1758 3039580 ChemDiv3_014003 Cc1ccccc1NC(=S)N(CCCN2CCCC2)Cc3cccn3Cc4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M12 compound treatment 0.398 0.148 2.11 0.256 0.0214 0.36 1.7481 0.8155 3039581 ChemDiv3_014004 FC(F)(F)c1ccccc1CNC(=O)CC2CC3CCC2C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M13 compound treatment 0.339 0.0888 1.27 0.241 0.00637 0.11 0.9733 0.764 3120868 ChemDiv3_014005 NC(=O)C1CCN(CC1)C(=O)c2ccc(/C=C\3/Oc4ccccc4N(Cc5ccccc5F)C3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M14 compound treatment 0.422 0.172 2.46 0.293 0.0584 0.98 2.4299 0.9187 3039583 ChemDiv3_014006 Fc1ccccc1CCNC(=O)c2ccc3ccccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M15 compound treatment 0.359 0.109 1.56 0.287 0.0524 0.88 1.7215 0.9635 3039585 ChemDiv3_014007 CCc1ccccc1NC(=S)N2CCC(CC2)N(C)CCN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M16 compound treatment 0.435 0.185 2.64 0.281 0.0464 0.78 2.419 0.8781 3120869 ChemDiv3_014008 COc1ccc(NC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M17 compound treatment 0.337 0.0867 1.24 0.234 -6.25E-4 -0.01 0.87 0.7011 3120870 ChemDiv3_014009 COc1cccc(/C=C\2/Sc3ccc(cc3NC2=O)C(=O)N4CC(C)CC(C)C4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M18 compound treatment 0.392 0.142 2.03 0.275 0.0404 0.68 1.9129 0.8948 3039587 ChemDiv3_014010 Cc1ccc(cc1I)C(=O)NC2CCCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M19 compound treatment 0.421 0.171 2.44 0.277 0.0424 0.71 2.2299 0.8766 3120871 ChemDiv3_014011 CC(C)N(CCc1ccncc1)C(=S)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M20 compound treatment 0.386 0.136 1.94 0.265 0.0304 0.51 1.7335 0.8635 3039589 ChemDiv3_014012 COc1ccc(C(=O)NCc2ccccc2)c(OC)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M21 compound treatment 0.404 0.154 2.2 0.277 0.0424 0.71 2.058 0.8904 3120872 ChemDiv3_014013 COc1ccc(cc1OC)C2CCCN2C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M22 compound treatment 0.381 0.131 1.87 0.247 0.0124 0.21 1.4693 0.7808 3039591 ChemDiv3_014014 Cc1cc(NC(=O)CCCC(=O)c2ccccc2)n[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M23 mock treatment 0.26 0.00975 0.14 0.256 0.0214 0.36 0.3523 0.9153 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 M24 mock treatment 0.245 -0.00525 -0.08 0.239 0.00437 0.07 -0.0012 -0.0112 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N01 compound treatment 0.256 0.00575 0.08 0.254 0.0194 0.33 0.2881 0.8589 3120873 ChemDiv3_014015 COc1ccc(cc1)N2CCN(CC2)C(=O)CCC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N02 compound treatment 0.337 0.0867 1.24 0.272 0.0374 0.63 1.321 0.9501 1672196 ChemDiv3_014016 COc1ccc(cc1)C(=O)NC(c2ccc(C)cc2)c3cc(Cl)c4cccnc4c3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N03 compound treatment 0.28 0.0298 0.43 0.273 0.0384 0.64 0.7563 0.9798 1611897 ChemDiv3_014017 Cc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N04 compound treatment 0.33 0.0798 1.14 0.275 0.0404 0.68 1.2858 0.9691 1269317 ChemDiv3_014018 Oc1c(CC(=O)NCc2ccccc2Cl)c(=O)[nH]c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N05 compound treatment 0.377 0.127 1.81 0.296 0.0614 1.03 2.0104 0.9641 3039594 ChemDiv3_014019 Cc1cc(Br)ccc1NC(=O)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N06 compound treatment 0.319 0.0688 0.98 0.291 0.0564 0.95 1.3644 0.9998 3120874 ChemDiv3_014020 CCn1c(=O)c(C2=Nc3ccccc3S(=O)(=O)N2)c(O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N07 compound treatment 0.362 0.112 1.6 0.269 0.0344 0.58 1.5382 0.9052 1592049 ChemDiv3_014021 CCOC(=O)C1=C(C)N(C)C(=C(C1c2ccc(C)s2)C(=O)OCC)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N08 compound treatment 0.339 0.0888 1.27 0.291 0.0564 0.95 1.5667 0.9895 1473031 ChemDiv3_014022 CCn1c(=O)n(CC(=O)N2CC(C)CC(C)C2)c(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N09 compound treatment 0.376 0.126 1.8 0.27 0.0354 0.59 1.6917 0.8931 3039597 ChemDiv3_014023 Oc1c(C(=O)C2CCC2)c(=O)oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N10 compound treatment 0.409 0.159 2.27 0.285 0.0504 0.85 2.2035 0.9094 1571851 ChemDiv3_014024 CC1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCN(CC4)c5ccc(F)cc5)c(C)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N11 compound treatment 0.343 0.0928 1.33 0.301 0.0664 1.11 1.7258 0.9962 3039657 ChemDiv3_014025 NC(=O)CSc1nnc(c2cccnc2)n1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N12 compound treatment 0.351 0.101 1.44 0.316 0.0814 1.37 1.9848 0.9996 1449739 ChemDiv3_014026 CCN(CC)c1nc(C)nc2sc(C(=O)N3CCCCCC3)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N13 compound treatment 0.316 0.0658 0.94 0.265 0.0304 0.51 1.0255 0.9586 1496672 ChemDiv3_014027 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N14 compound treatment 0.348 0.0978 1.4 0.304 0.0694 1.16 1.812 0.9959 1664336 ChemDiv3_014028 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NC4CCCCC4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N15 compound treatment 0.316 0.0658 0.94 0.257 0.0224 0.38 0.9306 0.9189 3039661 ChemDiv3_014029 CC1CCN(CC1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4Cl)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N16 compound treatment 0.373 0.123 1.76 0.302 0.0674 1.13 2.0411 0.9774 1520077 ChemDiv3_014030 COC(CNC(=O)c1ccc2n(c(C)nc2c1)c3cc(Cl)ccc3OC)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N17 compound treatment 0.338 0.0878 1.26 0.257 0.0224 0.38 1.1531 0.8801 3039662 ChemDiv3_014031 CCC1=C(C(c2cc(OC)c(OC)cc2OC)n3ncnc3N1)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N18 compound treatment 0.381 0.131 1.87 0.276 0.0414 0.69 1.8135 0.909 1180590 ChemDiv3_014032 CCOc1ccc(cc1)n2c(SCC(=O)NCc3ccco3)nc4[nH]nc(C)c4c2=N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N19 compound treatment 0.363 0.113 1.61 0.292 0.0574 0.96 1.8213 0.9696 3039664 ChemDiv3_014033 Cc1ccc(cc1C)C2CC(c3c(F)cccc3Cl)n4ncnc4N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N20 compound treatment 0.384 0.134 1.91 0.298 0.0634 1.06 2.1049 0.9616 1720516 ChemDiv3_014034 CC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N21 compound treatment 0.319 0.0688 0.98 0.264 0.0294 0.49 1.044 0.949 3120875 ChemDiv3_014035 COC(=O)C1=CN(Cc2ccc(Cl)cc2)C=C(C1c3cccc(Cl)c3)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N22 compound treatment 0.331 0.0808 1.16 0.263 0.0284 0.48 1.1535 0.9233 3039667 ChemDiv3_014036 Cc1n[nH]c(C)c1S(=O)(=O)N2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N23 mock treatment 0.303 0.0527 0.75 0.257 0.0224 0.38 0.7991 0.9481 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 N24 mock treatment 0.233 -0.0173 -0.25 0.224 -0.0106 -0.18 -0.3006 -0.9873 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O01 compound treatment 0.268 0.0177 0.25 0.244 0.00937 0.16 0.2908 0.9735 3120876 ChemDiv3_014037 Cc1ccc(C)c(c1)N2CCN(CC2)C(=O)c3ccc(/C=C/4\Oc5ccccc5NC4=O)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O02 compound treatment 0.272 0.0217 0.31 0.269 0.0344 0.58 0.6279 0.958 3039669 ChemDiv3_014038 Cc1cccc(/C=C\2/Oc3ccccc3N(CC(=O)N4CCC5(CC4)OCCO5)C2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O03 compound treatment 0.264 0.0138 0.2 0.277 0.0424 0.71 0.642 0.87 3120877 ChemDiv3_014039 Fc1cccc(/C=C\2/Oc3ccccc3N(CC(=O)N4CCN(CC4)c5ncccn5)C2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O04 compound treatment 0.26 0.00975 0.14 0.268 0.0334 0.56 0.4947 0.857 3120878 ChemDiv3_014040 Fc1ccc(CN2C(=O)/C(=C/c3ccccc3)/Sc4ccc(cc24)C(=O)N5CCCC5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O05 compound treatment 0.199 -0.0512 -0.73 0.275 0.0404 0.68 -0.0392 -0.0392 3039672 ChemDiv3_014041 FC(F)(F)c1cccc(Nc2cc(C(=O)NCc3cccnc3)c4ccccc4n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O06 compound treatment 0.294 0.0437 0.63 0.256 0.0214 0.36 0.6962 0.9651 3120879 ChemDiv3_014042 CCOc1ccc(cc1)c2nc(CSCC(=O)N3CCOCC3)c(C)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O07 compound treatment 0.306 0.0558 0.8 0.29 0.0554 0.93 1.2211 0.9971 3039673 ChemDiv3_014043 COc1ccc(Nc2cc(C(=O)NCCC(C)C)c3ccccc3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O08 compound treatment 0.291 0.0408 0.58 0.256 0.0214 0.36 0.6658 0.9728 3120880 ChemDiv3_014044 CC(C)CN(CC(C)C)C(=O)c1ccc2S/C(=C\c3ccccc3)/C(=O)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O09 compound treatment 0.243 -0.00725 -0.1 0.278 0.0434 0.73 0.4415 0.6003 3121069 ChemDiv3_014045 CC1CCCC(NC(=O)CC2Nc3ccccc3NC2=O)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O10 compound treatment 0.294 0.0437 0.63 0.21 -0.0246 -0.41 0.1502 0.2003 1418651 ChemDiv3_014046 COc1ccccc1NC(=O)c2c(NCc3cccs3)sc4CCCCCc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O11 compound treatment 0.27 0.0198 0.28 0.247 0.0124 0.21 0.3466 0.9886 3039738 ChemDiv3_014047 CN(C1CCCCC1)C2CCN(CC2)C(=S)Nc3cc(F)cc(F)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O12 compound treatment 0.3 0.0498 0.71 0.228 -0.00662 -0.11 0.4246 0.5895 3039740 ChemDiv3_014048 O=C(CC1CC2CCC1C2)NC3CCCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O13 compound treatment 0.266 0.0158 0.23 0.192 -0.0426 -0.72 -0.3466 -0.4621 3039741 ChemDiv3_014049 Fc1ccccc1CN2C(=O)/C(=C\c3ccc(cc3)C(=O)NC4CC4)/Oc5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O14 compound treatment 0.282 0.0318 0.45 0.266 0.0314 0.53 0.6935 0.9973 3039743 ChemDiv3_014050 CCCNC(=O)c1ccc2ccccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O15 compound treatment 0.291 0.0408 0.58 0.267 0.0324 0.54 0.7964 0.9994 3039744 ChemDiv3_014051 CCC(C)N(C)C1CCN(CC1)C(=S)Nc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O16 compound treatment 0.269 0.0187 0.27 0.215 -0.0196 -0.33 -0.0433 -0.1019 3039746 ChemDiv3_014052 CSc1ncccc1C(=O)NCc2ccccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O17 compound treatment 0.31 0.0597 0.85 0.202 -0.0326 -0.55 0.2171 0.2139 3121070 ChemDiv3_014053 COc1ccccc1/C=C\2/Sc3ccc(cc3N(C)C2=O)C(=O)N4CCN(CC4)c5ncccn5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O18 compound treatment 0.289 0.0388 0.55 0.252 0.0174 0.29 0.5981 0.955 3039748 ChemDiv3_014054 Cc1cc(NC(=O)Cc2cccc3ccccc23)n[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O19 compound treatment 0.266 0.0158 0.23 0.262 0.0274 0.46 0.4842 0.9462 3121071 ChemDiv3_014055 CC(C)NC(=S)N(CCc1ccncc1)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O20 compound treatment 0.293 0.0428 0.61 0.247 0.0124 0.21 0.5793 0.897 3121072 ChemDiv3_014056 COc1ccc(C(=O)NCCc2ccc(O)cc2)c(OC)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O21 compound treatment 0.238 -0.0123 -0.18 0.226 -0.00862 -0.14 -0.2263 -0.9955 3039751 ChemDiv3_014057 Cc1ccsc1/C=C/C(=O)NCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O22 compound treatment 0.27 0.0198 0.28 0.238 0.00337 0.06 0.2398 0.8323 3121073 ChemDiv3_014058 COc1ccc(cc1)N2CCN(CC2)C(=O)CCCC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O23 mock treatment 0.259 0.00875 0.13 0.24 0.00537 0.09 0.1523 0.9871 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 O24 mock treatment 0.22 -0.0302 -0.43 0.204 -0.0306 -0.51 -0.6694 -0.9963 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P01 compound treatment 0.259 0.00875 0.13 0.226 -0.00862 -0.14 -0.0139 -0.0724 1113275 ChemDiv3_014059 O=C(CCC(=O)c1ccccc1)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P02 compound treatment 0.285 0.0348 0.5 0.26 0.0254 0.43 0.6526 0.997 1223469 ChemDiv3_014060 CCn1cnc2sc(C(=O)N(Cc3ccco3)Cc4ccc(cc4)N(C)C)c(C)c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P03 compound treatment 0.271 0.0208 0.3 0.294 0.0594 1.0 0.9145 0.8795 1132336 ChemDiv3_014061 COc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P04 compound treatment 0.273 0.0227 0.33 0.287 0.0524 0.88 0.8517 0.9086 1194685 ChemDiv3_014062 CCCn1c(=O)c(CC(=O)OCC)c(O)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P05 compound treatment 0.297 0.0468 0.67 0.261 0.0264 0.44 0.7859 0.9799 3039754 ChemDiv3_014063 FC(F)(F)c1cccc(CNC(=O)c2cccs2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P06 compound treatment 0.27 0.0198 0.28 0.24 0.00537 0.09 0.2635 0.8887 3121074 ChemDiv3_014064 CC(C)Cn1c(=O)c(C2=Nc3ccccc3S(=O)(=O)N2)c(O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P07 compound treatment 0.26 0.00975 0.14 0.262 0.0274 0.46 0.4235 0.882 1400079 ChemDiv3_014065 CC(=O)Nc1c(OC(=O)C)ccc2c(C)cc(=O)oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P08 compound treatment 0.262 0.0118 0.17 0.261 0.0264 0.44 0.4319 0.912 1718046 ChemDiv3_014066 Oc1cccc(NC(=O)CCn2c(=S)oc3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P09 compound treatment 0.313 0.0628 0.9 0.267 0.0324 0.54 1.0189 0.9711 3039758 ChemDiv3_014067 COc1ccc2n(C)c3ccccc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P10 compound treatment 0.306 0.0558 0.8 0.276 0.0414 0.69 1.0549 0.9976 1122184 ChemDiv3_014068 COc1cccc(NC(=O)CNC(=O)Cn2cnc3sc4CCCCc4c3c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P11 compound treatment 0.333 0.0828 1.18 0.267 0.0324 0.54 1.2212 0.9376 3039818 ChemDiv3_014069 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P12 compound treatment 0.3 0.0498 0.71 0.246 0.0114 0.19 0.6382 0.8662 1425898 ChemDiv3_014070 CCOC(=O)c1ccccc1NC(=O)c2sc3nc(C)nc(N(CC)CC)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P13 compound treatment 0.321 0.0707 1.01 0.269 0.0344 0.58 1.1235 0.9645 1266683 ChemDiv3_014071 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCOCC4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P14 compound treatment 0.311 0.0607 0.87 0.263 0.0284 0.48 0.9512 0.9599 1619997 ChemDiv3_014072 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P15 compound treatment 0.28 0.0298 0.43 0.25 0.0154 0.26 0.4834 0.9713 1580461 ChemDiv3_014073 COC(CNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCC(C)CC3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P16 compound treatment 0.278 0.0278 0.4 0.242 0.00737 0.12 0.3682 0.8856 3121075 ChemDiv3_014074 CC1CC(C)CN(C1)C(=O)Cn2cnc3sc(C(=O)N(C)Cc4ccccc4)c(C)c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P17 compound treatment 0.288 0.0377 0.54 0.241 0.00637 0.11 0.4575 0.8311 3121076 ChemDiv3_014075 CN(C)C(=O)C1=C(C)Nc2nc3ccccc3n2C1c4ccc(Br)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P18 compound treatment 0.235 -0.0153 -0.22 0.244 0.00937 0.16 -0.043 -0.1598 1190662 ChemDiv3_014076 Cc1n[nH]c2nc(SCC(=O)NCCc3ccccc3)n(c4ccccc4Cl)c(=N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P19 compound treatment 0.337 0.0867 1.24 0.291 0.0564 0.95 1.5465 0.991 1542072 ChemDiv3_014077 CC1=C(C(C2=C(CCCC2=O)N1)c3cccs3)C(=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P20 compound treatment 0.31 0.0597 0.85 0.271 0.0364 0.61 1.036 0.9864 3039823 ChemDiv3_014078 CSCCC1N2C(=S)NC(C)(C)CC2(C)N(N)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P21 compound treatment 0.313 0.0628 0.9 0.273 0.0384 0.64 1.0901 0.9868 3121077 ChemDiv3_014079 CCOC(=O)C1=CN(C=C(C1c2ccccc2Br)C(=O)OCC)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P22 compound treatment 0.299 0.0488 0.7 0.285 0.0504 0.85 1.0909 0.9954 3039825 ChemDiv3_014080 CC(=O)Nc1nc(cs1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P23 mock treatment 0.3 0.0498 0.71 0.257 0.0224 0.38 0.7687 0.9554 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2040 P24 mock treatment 0.196 -0.0543 -0.78 0.234 -6.25E-4 -0.01 -0.5561 -0.7166 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A01 compound treatment 0.212 -0.023 -0.33 0.223 -0.0144 -0.24 -0.4034 -0.9887 3121078 ChemDiv3_014081 CCOc1ccc2nc(sc2c1)C(=O)N3CCCC(C)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A02 compound treatment 0.222 -0.013 -0.19 0.238 5.81E-4 0.01 -0.1243 -0.669 1329091 ChemDiv3_014082 COc1ccc(cc1)C2=NC(NC(C2)c3ccccc3O)c4ccccc4OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A03 compound treatment 0.242 0.00703 0.1 0.252 0.0146 0.24 0.2442 0.9228 3039828 ChemDiv3_014083 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N3CCN(CC3)c4cc(Cl)ccc4C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A04 compound treatment 0.209 -0.026 -0.37 0.224 -0.0134 -0.23 -0.4219 -0.9713 1633854 ChemDiv3_014084 CCOc1ccc(cc1)N(C)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCC4CCCO4)c(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A05 compound treatment 0.228 -0.00697 -0.1 0.23 -0.00742 -0.12 -0.1585 -0.9939 3121079 ChemDiv3_014085 CCOC(=O)c1cc(c2ccccc2)n(c1C)c3cccc(c3)C(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A06 compound treatment 0.218 -0.017 -0.24 0.223 -0.0144 -0.24 -0.3427 -1.0 1351188 ChemDiv3_014086 COC(CNC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A07 compound treatment 0.199 -0.036 -0.51 0.214 -0.0234 -0.39 -0.6417 -0.9912 3121080 ChemDiv3_014087 Cc1noc(/C=C/c2ccco2)c1S(=O)(=O)N3CCC(CC3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A08 compound treatment 0.224 -0.011 -0.16 0.215 -0.0224 -0.38 -0.377 -0.9248 3039830 ChemDiv3_014088 Brc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A09 compound treatment 0.239 0.00403 0.06 0.219 -0.0184 -0.31 -0.1778 -0.5654 3121081 ChemDiv3_014089 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3c(C)noc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A10 compound treatment 0.212 -0.023 -0.33 0.21 -0.0274 -0.46 -0.5577 -0.9863 3039832 ChemDiv3_014090 CC(C)OC(=O)CN1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A11 compound treatment 0.218 -0.017 -0.24 0.225 -0.0124 -0.21 -0.319 -0.9971 1112897 ChemDiv3_014091 Cc1ccc(cc1)c2cc3ccccn3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A12 compound treatment 0.234 -9.68E-4 -0.01 0.25 0.0126 0.21 0.1395 0.6593 3121082 ChemDiv3_014092 CC(NC(=O)CCn1c(=S)oc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A13 compound treatment 0.237 0.00203 0.03 0.238 5.81E-4 0.01 0.0274 0.8952 3039835 ChemDiv3_014093 CC1CCC(CC1)NC(=O)c2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A14 compound treatment 0.238 0.00303 0.04 0.221 -0.0164 -0.28 -0.1642 -0.5886 3039892 ChemDiv3_014094 Brc1ccc(cc1)S(=O)(=O)CCC(=O)N2CCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A15 compound treatment 0.196 -0.039 -0.56 0.188 -0.0494 -0.83 -0.9806 -0.9813 3039893 ChemDiv3_014095 CN(C)/C=C/c1onc(C)c1S(=O)(=O)N(C)CCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A16 compound treatment 0.204 -0.031 -0.44 0.219 -0.0184 -0.31 -0.5318 -0.9845 1322055 ChemDiv3_014096 Nc1ccc(cc1)N2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A17 compound treatment 0.22 -0.015 -0.21 0.228 -0.00942 -0.16 -0.2632 -0.9889 3039895 ChemDiv3_014097 CC(C)NS(=O)(=O)c1c(C)noc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A18 compound treatment 0.11 -0.125 -1.79 0.103 -0.134 -2.26 -2.8593 -0.9934 1643280 ChemDiv3_014098 Nc1ccc(Oc2ccc3ccccc3c2Cl)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A19 compound treatment 0.208 -0.027 -0.39 0.218 -0.0194 -0.33 -0.5032 -0.9965 3039897 ChemDiv3_014099 CNC(=O)C1CCN(CC1)S(=O)(=O)c2c(C)noc2/C=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A20 compound treatment 0.237 0.00203 0.03 0.235 -0.00242 -0.04 -0.0082 -0.1634 1143154 ChemDiv3_014100 OC(=O)c1ccc2C(=O)N(CCC3=CCCCC3)C(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A21 compound treatment 0.242 0.00703 0.1 0.219 -0.0184 -0.31 -0.1475 -0.4536 3039899 ChemDiv3_014101 COc1ccccc1CC(=O)Nc2ccc(cc2)c3noc(COc4ccc(Cl)c(C)c4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A22 compound treatment 0.225 -0.00997 -0.14 0.23 -0.00742 -0.12 -0.1889 -0.9977 3039901 ChemDiv3_014102 Cc1ccc(cc1)c2c(oc(=O)c3ccccc23)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A23 mock treatment 0.238 0.00303 0.04 0.214 -0.0234 -0.39 -0.2473 -0.6253 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 A24 mock treatment 0.22 -0.015 -0.21 0.215 -0.0224 -0.38 -0.4175 -0.9643 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B01 compound treatment 0.232 -0.00297 -0.04 0.228 -0.00942 -0.16 -0.1418 -0.8663 3121083 ChemDiv3_014103 COc1ccc(cc1)c2n[nH]cc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B02 compound treatment 0.218 -0.017 -0.24 0.237 -4.19E-4 -0.01 -0.1766 -0.7273 3121084 ChemDiv3_014104 CC(C)C1=NC(NN1c2ccccc2)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B03 compound treatment 0.239 0.00403 0.06 0.214 -0.0234 -0.39 -0.2372 -0.597 1037837 ChemDiv3_014105 Nc1ccc(OCc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B04 compound treatment 0.242 0.00703 0.1 0.225 -0.0124 -0.21 -0.0763 -0.3295 3121085 ChemDiv3_014106 CC(N1C(=O)NC(C2=C1CC(C)(C)CC2=O)(C(F)(F)F)C(F)(F)F)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B05 compound treatment 0.283 0.048 0.69 0.237 -4.19E-4 -0.01 0.4808 0.6998 3039905 ChemDiv3_014107 OC(=O)Cc1ccc(NCc2ccc(Br)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B06 compound treatment 0.272 0.037 0.53 0.24 0.00258 0.04 0.4052 0.7624 3039906 ChemDiv3_014108 O=c1[nH]c(=O)c2[nH]cnc2n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B07 compound treatment 0.237 0.00203 0.03 0.242 0.00458 0.08 0.0749 0.9115 3121086 ChemDiv3_014109 OC(=O)CCSCc1ccccc1F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B08 compound treatment 0.24 0.00503 0.07 0.254 0.0166 0.28 0.2477 0.8616 3121087 ChemDiv3_014110 Nc1cc(=O)n2C(CS(=O)(=O)c3ccccc3)CSc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B09 compound treatment 0.248 0.013 0.19 0.241 0.00358 0.06 0.1743 0.89 3039909 ChemDiv3_014111 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)O)c(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B10 compound treatment 0.271 0.036 0.52 0.241 0.00358 0.06 0.4069 0.7842 3121088 ChemDiv3_014112 CCCc1cc(=O)c2c(=O)n([nH]c2[nH]1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B11 compound treatment 0.25 0.015 0.22 0.242 0.00458 0.08 0.2064 0.9039 1619398 ChemDiv3_014113 COc1ccccc1n2c(C)nc3cc(ccc23)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B12 compound treatment 0.244 0.00903 0.13 0.254 0.0166 0.28 0.2881 0.9391 3121089 ChemDiv3_014114 NC1=NC(N2C(=N1)Sc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B13 compound treatment 0.237 0.00203 0.03 0.224 -0.0134 -0.23 -0.1387 -0.6108 3039912 ChemDiv3_014115 CCn1c2ccccc2c3nn(C)c(=N)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B14 compound treatment 0.069 -0.166 -2.37 0.065 -0.172 -2.89 -3.7249 -0.9952 3121090 ChemDiv3_014116 C=CCNc1nc2c([nH]c3ccccc23)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B15 compound treatment 0.249 0.014 0.2 0.241 0.00358 0.06 0.1844 0.8802 3039968 ChemDiv3_014117 CN(Cc1ccccc1)S(=O)(=O)c2ccc3n(C)c(=O)n(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B16 compound treatment 0.235 3.23E-5 0.0 0.233 -0.00442 -0.07 -0.0521 -0.7027 3039970 ChemDiv3_014118 NC1=C(C#N)C(c2ccncc2)c3c(O)ncnc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B17 compound treatment 0.232 -0.00297 -0.04 0.255 0.0176 0.3 0.1786 0.5992 3039971 ChemDiv3_014119 OC(=O)c1ccc(cc1)C2NC(=O)C(=C(SCc3ccccc3)S2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B18 compound treatment 0.257 0.022 0.32 0.24 0.00258 0.04 0.2535 0.7968 3039972 ChemDiv3_014120 COC(=O)c1ccc2c(=O)n3nc(N)sc3nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B19 compound treatment 0.265 0.03 0.43 0.259 0.0216 0.36 0.5599 0.9964 3039974 ChemDiv3_014121 O=c1[nH]c(CSc2nc3ccccc3o2)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B20 compound treatment 0.252 0.017 0.24 0.256 0.0186 0.31 0.3928 0.9925 3039976 ChemDiv3_014122 CCCCN1COc2ccc3c(C)cc(=O)oc3c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B21 compound treatment 0.306 0.071 1.02 0.276 0.0386 0.65 1.1763 0.9763 3039977 ChemDiv3_014123 CC1CC(=O)C2=C(C1)Nc3nc4ccccc4n3C2c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B22 compound treatment 0.233 -0.00197 -0.03 0.234 -0.00342 -0.06 -0.0605 -0.9462 3039979 ChemDiv3_014124 NC1=NC(N(CCc2ccc(F)cc2)C(=N1)N)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B23 mock treatment 0.234 -9.68E-4 -0.01 0.23 -0.00742 -0.12 -0.0978 -0.7809 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 B24 mock treatment 0.25 0.015 0.22 0.243 0.00558 0.09 0.2183 0.9307 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C01 compound treatment 0.222 -0.013 -0.19 0.242 0.00458 0.08 -0.0768 -0.3825 3121091 ChemDiv3_014125 CC(C)c1ccc(cc1)n2cccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C02 compound treatment 0.206 -0.029 -0.41 0.211 -0.0264 -0.44 -0.6065 -0.9994 1717842 ChemDiv3_014126 CCOc1ccc(cc1)C2=NC(NC(C2)c3ccccc3O)c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C03 compound treatment 0.25 0.015 0.22 0.19 -0.0474 -0.8 -0.4107 -0.4982 3039981 ChemDiv3_014127 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N3CCc4ccccc34)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C04 compound treatment 0.197 -0.038 -0.54 0.228 -0.00942 -0.16 -0.4958 -0.8766 1387961 ChemDiv3_014128 COC(CNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N(C)c3ccc(cc3)C(C)C)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C05 compound treatment 0.113 -0.122 -1.74 0.248 0.0106 0.18 -1.108 -0.6319 3121277 ChemDiv3_014129 O=C(NC1CCCC1)C2CCCN(C2)S(=O)(=O)c3cccc4cccnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C06 compound treatment 0.25 0.015 0.22 0.255 0.0176 0.3 0.3607 0.9879 1469378 ChemDiv3_014130 COc1ccc(cc1)S(=O)(=O)NC(CC(=O)N2CCC3(CC2)OCCO3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C07 compound treatment 0.225 -0.00997 -0.14 0.255 0.0176 0.3 0.1078 0.329 3121278 ChemDiv3_014131 O=C1Cc2cc(ccc2N1)S(=O)(=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C08 compound treatment 0.228 -0.00697 -0.1 0.249 0.0116 0.19 0.067 0.3066 3039984 ChemDiv3_014132 CCOc1ccccc1NC(=O)CCN2CCN(CC2)S(=O)(=O)c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C09 compound treatment 0.223 -0.012 -0.17 0.222 -0.0154 -0.26 -0.304 -0.9799 1032549 ChemDiv3_014133 CCOC(=O)C1CCCCN1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C10 compound treatment 0.263 0.028 0.4 0.245 0.00758 0.13 0.3735 0.8879 1171382 ChemDiv3_014134 CC(C)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C11 compound treatment 0.233 -0.00197 -0.03 0.265 0.0276 0.46 0.3074 0.6629 3039986 ChemDiv3_014135 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C12 compound treatment 0.246 0.011 0.16 0.241 0.00358 0.06 0.1541 0.9125 1318029 ChemDiv3_014136 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)N4CCC(=CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C13 compound treatment 0.23 -0.00497 -0.07 0.218 -0.0194 -0.33 -0.2807 -0.8415 3121279 ChemDiv3_014137 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)N3CCc4ccccc4C3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C14 compound treatment 0.126 -0.109 -1.56 0.24 0.00258 0.04 -1.0715 -0.6872 3039989 ChemDiv3_014138 Brc1ccc(cc1)S(=O)(=O)CCC(=O)N2CC(=O)N(CCc3ccccc3)C(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C15 compound treatment 0.166 -0.069 -0.99 0.11 -0.127 -2.14 -2.2098 -0.9383 3121280 ChemDiv3_014139 CC(C)c1ccc(cc1)N(C)S(=O)(=O)c2c(C)noc2/C=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C16 compound treatment 0.218 -0.017 -0.24 0.234 -0.00342 -0.06 -0.2122 -0.8508 1627807 ChemDiv3_014140 OC(=O)c1ccc2ncccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C17 compound treatment 0.04 -0.195 -2.79 0.225 -0.0124 -0.21 -2.1193 -0.7578 3121281 ChemDiv3_014141 O=C(Cn1cnc(c1)S(=O)(=O)N2CCCC2)NC3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C18 compound treatment 0.256 0.021 0.3 0.224 -0.0134 -0.23 0.0535 0.1423 3038771 ChemDiv3_014142 Cc1cc(nn1CC(=O)O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C19 compound treatment 0.054 -0.181 -2.59 0.234 -0.00342 -0.06 -1.8709 -0.7226 3038773 ChemDiv3_014143 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCSc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C20 compound treatment 0.221 -0.014 -0.2 0.228 -0.00942 -0.16 -0.2531 -0.9933 1727323 ChemDiv3_014144 O=C(Nc1ccccc1)c2ccc3C(=O)N(CCC4=CCCCC4)C(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C21 compound treatment 0.235 3.23E-5 0.0 0.24 0.00258 0.04 0.031 0.7146 3038774 ChemDiv3_014145 CCOC(=O)C1C(/C=C/c2ccccc2)C(C(=O)OCC)C(C)(O)CC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C22 compound treatment 0.041 -0.194 -2.77 0.229 -0.00842 -0.14 -2.0618 -0.7422 3038776 ChemDiv3_014146 CC1CCc2[nH]nc(C(=O)O)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C23 mock treatment 0.042 -0.193 -2.76 0.041 -0.196 -3.3 -4.2828 -0.9961 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 C24 mock treatment 0.222 -0.013 -0.19 0.214 -0.0234 -0.39 -0.4091 -0.9412 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D01 compound treatment 0.231 -0.00397 -0.06 0.244 0.00658 0.11 0.038 0.3058 3038777 ChemDiv3_014147 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)O)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D02 compound treatment 0.224 -0.011 -0.16 0.202 -0.0354 -0.59 -0.5313 -0.8641 3038779 ChemDiv3_014148 CC1=NN(C(=O)C21C3CC(C=C3)C2(C(F)(F)F)C(F)(F)F)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D03 compound treatment 0.251 0.016 0.23 0.257 0.0196 0.33 0.3945 0.9845 1041548 ChemDiv3_014149 CC(C)(C)c1cc(O)cc(c1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D04 compound treatment 0.277 0.042 0.6 0.303 0.0656 1.1 1.2034 0.9595 3038781 ChemDiv3_014150 C(Nc1nc[n+]2CCn3cnc1c32)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D05 compound treatment 0.184 -0.051 -0.73 0.182 -0.0554 -0.93 -1.1732 -0.9927 3121282 ChemDiv3_014151 OC(=O)c1ccccc1NCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D06 compound treatment 0.296 0.061 0.87 0.237 -4.19E-4 -0.01 0.6123 0.7014 3121283 ChemDiv3_014152 C=CCn1cnc2c(NCc3ccccc3)ncnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D07 compound treatment 0.247 0.012 0.17 0.278 0.0406 0.68 0.6033 0.8588 3038783 ChemDiv3_014153 COc1ccc(CN2CC(CC2=O)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D08 compound treatment 0.27 0.035 0.5 0.219 -0.0184 -0.31 0.1357 0.2305 3121284 ChemDiv3_014154 Nc1ccccc1SC2=CS(=O)(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D09 compound treatment 0.248 0.013 0.19 0.304 0.0666 1.12 0.922 0.8138 3038785 ChemDiv3_014155 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc2oc(C(=O)O)c(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D10 compound treatment 0.242 0.00703 0.1 0.297 0.0596 1.0 0.7782 0.7743 3121285 ChemDiv3_014156 COc1ccc(cc1)c2nc(C=C3C(=O)c4ccccc4C3=O)c5ccccn25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D11 compound treatment 0.272 0.037 0.53 0.25 0.0126 0.21 0.5239 0.9187 3038787 ChemDiv3_014157 COc1ccc2[nH]c(=O)c(cc2c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D12 compound treatment 0.132 -0.103 -1.47 0.121 -0.116 -1.95 -2.4231 -0.9903 3121286 ChemDiv3_014158 Cc1[nH]c2ccccc2c1C3(O)C(=O)N(Cc4ccc(C)cc4)c5ccc(Br)cc53 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D13 compound treatment 0.311 0.076 1.09 0.259 0.0216 0.36 1.0251 0.8943 3038789 ChemDiv3_014159 Cc1nc(N)c(C#N)c(c2ccc(Br)s2)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D14 compound treatment 0.277 0.042 0.6 0.263 0.0256 0.43 0.7287 0.9864 3121287 ChemDiv3_014160 CC(=O)n1c2sc(N3CCOCC3)c(c4ccccc4)c2c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D15 compound treatment 0.273 0.038 0.54 0.275 0.0376 0.63 0.8307 0.9973 3121288 ChemDiv3_014161 CC1CCc2c(C1)sc3ncnc(SCC(=O)Nc4nsc(n4)c5ccccc5C)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D16 compound treatment 0.284 0.049 0.7 0.283 0.0456 0.77 1.0369 0.9991 3038791 ChemDiv3_014162 COC(=O)C1=C(N)Oc2c(oc(CO)cc2=O)C1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D17 compound treatment 0.285 0.05 0.72 0.277 0.0396 0.66 0.9758 0.9993 3038792 ChemDiv3_014163 CC(C)(C)N1CC(CC1=O)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D18 compound treatment 0.275 0.04 0.57 0.262 0.0246 0.41 0.6966 0.9871 3121289 ChemDiv3_014164 OC(=O)CCc1nn2c(=O)c3ccccc3nc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D19 compound treatment 0.254 0.019 0.27 0.27 0.0326 0.55 0.5792 0.9481 3038794 ChemDiv3_014165 COc1ccc2CCc3sc(C)nc3-c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D20 compound treatment 0.263 0.028 0.4 0.28 0.0426 0.71 0.7889 0.9627 3121290 ChemDiv3_014166 Cc1ccc(cc1)c2n[nH]c3nc(cc(c4cccc5ccccc45)c23)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D21 compound treatment 0.31 0.075 1.07 0.268 0.0306 0.51 1.1218 0.943 3038796 ChemDiv3_014167 CC1=NC(N=C(O1)N2CCCCC2)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D22 compound treatment 0.273 0.038 0.54 0.255 0.0176 0.3 0.5933 0.9587 3121291 ChemDiv3_014168 Nc1cnn(c2ccccc2)c(=O)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D23 mock treatment 0.261 0.026 0.37 0.247 0.00958 0.16 0.377 0.9295 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 D24 mock treatment 0.217 -0.018 -0.26 0.233 -0.00442 -0.07 -0.2342 -0.8755 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E01 compound treatment 0.244 0.00903 0.13 0.223 -0.0144 -0.24 -0.0798 -0.2908 3121292 ChemDiv3_014169 CC1Cc2ccccc2N1C(=O)CSCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E02 compound treatment 0.061 -0.174 -2.49 0.064 -0.173 -2.91 -3.8177 -0.997 3038858 ChemDiv3_014170 Oc1ccccc1C2CC(=NC(N2)c3ccc(Br)cc3)c4cccc(Br)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E03 compound treatment 0.279 0.044 0.63 0.252 0.0146 0.24 0.6184 0.9152 3038859 ChemDiv3_014171 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N3CCCCCC3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E04 compound treatment 0.289 0.054 0.77 0.276 0.0386 0.65 1.0044 0.9961 3038861 ChemDiv3_014172 CCCNC(=O)Cn1cnc2sc(C(=O)NCCCN3CCOCC3)c(C)c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E05 compound treatment 0.224 -0.011 -0.16 0.279 0.0416 0.7 0.3826 0.5348 3038862 ChemDiv3_014173 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCCC3C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E06 compound treatment 0.239 0.00403 0.06 0.283 0.0456 0.77 0.5817 0.7583 1313876 ChemDiv3_014174 COc1ccc(cc1)C(CC(=O)NC2CCCC2)NS(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E07 compound treatment 0.236 0.00103 0.01 0.26 0.0226 0.38 0.2784 0.7341 3038865 ChemDiv3_014175 O=C1Cc2cc(ccc2N1)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E08 compound treatment 0.299 0.064 0.92 0.268 0.0306 0.51 1.0106 0.9625 3121293 ChemDiv3_014176 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)/C=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E09 compound treatment 0.296 0.061 0.87 0.265 0.0276 0.46 0.9446 0.956 3038867 ChemDiv3_014177 CN(CC(=O)NC1CCCC1)S(=O)(=O)c2ccc3nc(C)sc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E10 compound treatment 0.266 0.031 0.44 0.278 0.0406 0.68 0.7955 0.9785 3121294 ChemDiv3_014178 COc1ccc(cc1)C(=O)N2CCN(CC2)S(=O)(=O)c3cc(Cl)ccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E11 compound treatment 0.28 0.045 0.64 0.282 0.0446 0.75 0.9846 0.9972 3038869 ChemDiv3_014179 Cn1cnc(c1)S(=O)(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E12 compound treatment 0.287 0.052 0.74 0.293 0.0556 0.93 1.1859 0.9937 1381314 ChemDiv3_014180 Cc1cccc(NC(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E13 compound treatment 0.27 0.035 0.5 0.225 -0.0124 -0.21 0.2069 0.3813 3121295 ChemDiv3_014181 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)NC3CCCC(C)C3C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E14 compound treatment 0.278 0.043 0.62 0.262 0.0246 0.41 0.727 0.9811 3038872 ChemDiv3_014182 COc1ccc(cc1)S(=O)(=O)CCC(=O)Nc2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E15 compound treatment 0.267 0.032 0.46 0.247 0.00958 0.16 0.4377 0.9014 3121296 ChemDiv3_014183 Cc1noc(/C=C/N2CCOCC2)c1S(=O)(=O)N3CCN(CC3)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E16 compound treatment 0.165 -0.07 -1.0 0.133 -0.104 -1.75 -1.9469 -0.9647 3038873 ChemDiv3_014184 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(Br)cc2C(NCC(=O)O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E17 compound treatment 0.278 0.043 0.62 0.265 0.0276 0.46 0.7626 0.9901 3121297 ChemDiv3_014185 CN(CC(=O)NCc1ccccc1)S(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E18 compound treatment 0.245 0.01 0.14 0.251 0.0136 0.23 0.2626 0.9751 1043920 ChemDiv3_014186 NC(=O)C1(CCN(Cc2ccccc2)CC1)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E19 compound treatment 0.261 0.026 0.37 0.261 0.0236 0.4 0.5432 0.9995 3038876 ChemDiv3_014187 Cc1cc(C)cc(NS(=O)(=O)c2ccc3N(CCOc3c2)C(=O)c4ccco4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E20 compound treatment 0.24 0.00503 0.07 0.267 0.0296 0.5 0.402 0.8012 1431633 ChemDiv3_014188 COc1ccc(cc1)N2CCN(CC2)c3ccc(NC(=O)c4ccc(OC)cc4)cc3C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E21 compound treatment 0.256 0.021 0.3 0.257 0.0196 0.33 0.4451 0.999 1147292 ChemDiv3_014189 COc1ccccc1CNC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccc5F)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E22 compound treatment 0.228 -0.00697 -0.1 0.248 0.0106 0.18 0.0551 0.2706 3038879 ChemDiv3_014190 CC(CN1CCCCC1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E23 mock treatment 0.226 -0.00897 -0.13 0.231 -0.00642 -0.11 -0.1669 -0.9962 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 E24 mock treatment 0.233 -0.00197 -0.03 0.226 -0.0114 -0.19 -0.1554 -0.8023 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F01 compound treatment 0.229 -0.00597 -0.09 0.231 -0.00642 -0.11 -0.1365 -0.9933 3038881 ChemDiv3_014191 Cc1c(cc(c2ccccc2)n1Cc3ccccc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F02 compound treatment 0.215 -0.02 -0.29 0.298 0.0606 1.02 0.517 0.4895 3038929 ChemDiv3_014192 FC(F)(F)C1(N=C(N2C=CC=CC2=N1)c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F03 compound treatment 0.287 0.052 0.74 0.281 0.0436 0.73 1.0435 1.0 1013222 ChemDiv3_014193 CCN(CC)c1ccc(cc1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F04 compound treatment 0.281 0.046 0.66 0.267 0.0296 0.5 0.8166 0.9903 3121473 ChemDiv3_014194 Nc1ncnc2n(CCNCc3ccccc3)cnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F05 compound treatment 0.286 0.051 0.73 0.259 0.0216 0.36 0.7723 0.9477 3038931 ChemDiv3_014195 OC(=O)c1ccc2n(cnc2c1)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F06 compound treatment 0.305 0.07 1.0 0.284 0.0466 0.78 1.2611 0.9925 3121474 ChemDiv3_014196 COc1ccc(cc1OC)C(=O)OCC2CC(=NO2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F07 compound treatment 0.293 0.058 0.83 0.295 0.0576 0.97 1.2703 0.9971 3038933 ChemDiv3_014197 NNC(=O)c1ccc(CN2CCCCC2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F08 compound treatment 0.232 -0.00297 -0.04 0.227 -0.0104 -0.17 -0.1537 -0.854 3038995 ChemDiv3_014198 Cc1ccc(C(=O)O)c2C3C=CCC3[C@H](Nc12)c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F09 compound treatment 0.278 0.043 0.62 0.293 0.0556 0.93 1.0949 0.9796 3038997 ChemDiv3_014199 Cc1c(oc2ccc(cc12)S(=O)(=O)N3CCCC3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F10 compound treatment 0.297 0.062 0.89 0.229 -0.00842 -0.14 0.5275 0.5871 3038998 ChemDiv3_014200 C(N1CN(Cc2ccccc2)c3nc4ccccc4n3C1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F11 compound treatment 0.318 0.083 1.19 0.279 0.0416 0.7 1.3333 0.9679 1739322 ChemDiv3_014201 CC(C)(C)c1cc(CCC(=O)NN)cc(c1O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F12 compound treatment 0.303 0.068 0.97 0.303 0.0656 1.1 1.4664 0.9981 3039000 ChemDiv3_014202 CC(C)(C)NC1C=C(Sc2nc(cn12)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F13 compound treatment 0.298 0.063 0.9 0.297 0.0596 1.0 1.3446 0.9987 3039002 ChemDiv3_014203 Nc1nc2CCCCc2c(c3ccc(Br)s3)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F14 compound treatment 0.313 0.078 1.12 0.312 0.0746 1.25 1.6744 0.9984 1598994 ChemDiv3_014204 CC(=O)n1c2sc(N3CCCCC3)c(C#N)c2c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F15 compound treatment 0.319 0.084 1.2 0.303 0.0656 1.1 1.6282 0.999 3039004 ChemDiv3_014205 CCOc1ccc2nc(SCC(=O)N3CCN(C3)C(=O)c4ccc(C)cc4)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F16 compound treatment 0.23 -0.00497 -0.07 0.155 -0.0824 -1.38 -1.0284 -0.7424 3121475 ChemDiv3_014206 CCNc1nc2[nH]c(=O)c3C(C(=C(N)Oc3c2s1)C#N)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F17 compound treatment 0.331 0.096 1.37 0.281 0.0436 0.73 1.4885 0.9565 3039006 ChemDiv3_014207 C(Sc1nn2cnnc2s1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F18 compound treatment 0.316 0.081 1.16 0.296 0.0586 0.98 1.5148 0.9966 3039007 ChemDiv3_014208 Nn1c(=O)c2ccc(cc2[nH]c1=S)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F19 compound treatment 0.265 0.03 0.43 0.294 0.0566 0.95 0.9753 0.9357 3121476 ChemDiv3_014209 COc1ccc(cc1)c2cc(n3nc(N)nc3n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F20 compound treatment 0.246 0.011 0.16 0.237 -4.19E-4 -0.01 0.1066 0.6749 3121477 ChemDiv3_014210 CC1=C(C(c2ccccc2)n3ncc(C(=O)Nc4ccccc4)c3N1)C(=O)Nc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F21 compound treatment 0.298 0.063 0.9 0.297 0.0596 1.0 1.3446 0.9987 3039010 ChemDiv3_014211 Cc1nn(c2OC(=NC(c12)(C(F)(F)F)C(F)(F)F)N3CCOCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F22 compound treatment 0.287 0.052 0.74 0.238 5.81E-4 0.01 0.5332 0.7163 3121478 ChemDiv3_014212 COc1ccc(Cl)cc1S(=O)(=O)Nc2ccc3C(=O)OCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F23 mock treatment 0.275 0.04 0.57 0.267 0.0296 0.5 0.756 0.9975 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 F24 mock treatment 0.243 0.00803 0.11 0.241 0.00358 0.06 0.1237 0.9543 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G01 compound treatment 0.209 -0.026 -0.37 0.273 0.0356 0.6 0.1596 0.227 3039012 ChemDiv3_014213 O=C(Cc1ccc(cc1)n2cccc2)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G02 compound treatment 0.229 -0.00597 -0.09 0.261 0.0236 0.4 0.2195 0.5421 1714096 ChemDiv3_014214 COc1cccc(c1)C2=NC(C)(C)NC(C2)c3ccccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G03 compound treatment 0.214 -0.021 -0.3 0.21 -0.0274 -0.46 -0.5375 -0.9785 3121479 ChemDiv3_014215 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)Nc3nc4ccc(Cl)cc4s3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G04 compound treatment 0.283 0.048 0.69 0.287 0.0496 0.83 1.0742 0.9955 1714352 ChemDiv3_014216 CCCNC(=O)Cn1cnc2sc(C(=O)N3CCC(Cc4ccccc4)CC3)c(C)c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G05 compound treatment 0.274 0.039 0.56 0.273 0.0356 0.6 0.8171 0.9994 3121480 ChemDiv3_014217 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)N3CCCCCC3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G06 compound treatment 0.305 0.07 1.0 0.331 0.0936 1.57 1.8189 0.9764 1220187 ChemDiv3_014218 COc1ccc(cc1)S(=O)(=O)NC(CC(=O)N2CCCCC2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G07 compound treatment 0.317 0.082 1.17 0.286 0.0486 0.82 1.4063 0.9842 3038882 ChemDiv3_014219 CN(C)/C=C/c1onc(C)c1S(=O)(=O)N(C)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G08 compound treatment 0.329 0.094 1.35 0.333 0.0956 1.6 2.0854 0.9962 1710074 ChemDiv3_014220 Cc1ccccc1CN2CCN(CC2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G09 compound treatment 0.252 0.017 0.24 0.306 0.0686 1.15 0.9862 0.8382 3038935 ChemDiv3_014221 CN(C)/C=C/c1onc(C)c1S(=O)(=O)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G10 compound treatment 0.294 0.059 0.84 0.269 0.0316 0.53 0.9719 0.9748 1284663 ChemDiv3_014222 CC(C)NC(=O)c1oc(=O)c2ccccc2c1c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G11 compound treatment 0.311 0.076 1.09 0.326 0.0886 1.49 1.8203 0.9882 3038937 ChemDiv3_014223 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G12 compound treatment 0.314 0.079 1.13 0.309 0.0716 1.2 1.6489 0.9995 1285233 ChemDiv3_014224 CC1CCCC(C)N1C(=O)CCN2C(=O)C3C4CC(C=C4)C3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G13 compound treatment 0.279 0.044 0.63 0.274 0.0366 0.61 0.8795 0.9999 3038939 ChemDiv3_014225 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)N(C)Cc3ccccc3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G14 compound treatment 0.287 0.052 0.74 0.278 0.0406 0.68 1.0079 0.999 3038941 ChemDiv3_014226 COc1ccc(cc1)S(=O)(=O)CCC(=O)N(C)c2ccc(OC)cc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G15 compound treatment 0.261 0.026 0.37 0.252 0.0146 0.24 0.4363 0.9793 3038942 ChemDiv3_014227 CCc1ccccc1N(C)S(=O)(=O)c2c(C)noc2/C=C/N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G16 compound treatment 0.265 0.03 0.43 0.281 0.0436 0.73 0.821 0.9678 1609499 ChemDiv3_014228 O=C(c1ccccc1)c2ccc3CCc4cccc2c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G17 compound treatment 0.259 0.024 0.34 0.228 -0.00942 -0.16 0.1313 0.347 3121481 ChemDiv3_014229 COc1ccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)NCc4ccccc4)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G18 compound treatment 0.276 0.041 0.59 0.253 0.0156 0.26 0.5999 0.9337 3038944 ChemDiv3_014230 OC(=O)c1cc(cc2ccccc12)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G19 compound treatment 0.258 0.023 0.33 0.283 0.0456 0.77 0.7739 0.9291 3121482 ChemDiv3_014231 O=C(N1NC2(CCCC2)NC1=O)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G20 compound treatment 0.244 0.00903 0.13 0.255 0.0176 0.3 0.3 0.9313 1570307 ChemDiv3_014232 CCN1CCc2c(C(=O)OC)c(N)sc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G21 compound treatment 0.259 0.024 0.34 0.2 -0.0374 -0.63 -0.201 -0.2808 1516404 ChemDiv3_014233 CN(Cc1ccccc1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccc5)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G22 compound treatment 0.223 -0.012 -0.17 0.249 0.0116 0.19 0.0164 0.0633 1147592 ChemDiv3_014234 CCOC(=O)CC(N)c1ccc(C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G23 mock treatment 0.21 -0.025 -0.36 0.221 -0.0164 -0.28 -0.4474 -0.9918 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 G24 mock treatment 0.222 -0.013 -0.19 0.225 -0.0124 -0.21 -0.2786 -0.9983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H01 compound treatment 0.209 -0.026 -0.37 0.232 -0.00542 -0.09 -0.327 -0.855 1184652 ChemDiv3_014235 Cc1ccc(cc1C)S(=O)(=O)CCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H02 compound treatment 0.242 0.00703 0.1 0.262 0.0246 0.41 0.3629 0.8545 3121483 ChemDiv3_014236 CCOc1ccc2N3C(=NC(NC3=O)(C(F)(F)F)C(F)(F)F)Sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H03 compound treatment 0.283 0.048 0.69 0.275 0.0376 0.63 0.9318 0.9991 3038948 ChemDiv3_014237 OC(=O)/C=C/c1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H04 compound treatment 0.303 0.068 0.97 0.303 0.0656 1.1 1.4664 0.9981 3121484 ChemDiv3_014238 COc1ccccc1C2=NOC(COC(=O)c3ccc4ccccc4n3)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H05 compound treatment 0.294 0.059 0.84 0.263 0.0256 0.43 0.9007 0.9508 1238998 ChemDiv3_014239 OC(=O)C1CCC(CNCc2ccncc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H06 compound treatment 0.286 0.051 0.73 0.303 0.0656 1.1 1.2945 0.9801 3121485 ChemDiv3_014240 CSc1nsc(SCC(=O)N2CCCc3ccccc23)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H07 compound treatment 0.294 0.059 0.84 0.281 0.0436 0.73 1.1143 0.9974 3038951 ChemDiv3_014241 Cc1ccc(CSCCC(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H08 compound treatment 0.299 0.064 0.92 0.311 0.0736 1.23 1.5209 0.9892 3038952 ChemDiv3_014242 Cc1ccn2cc(CSc3ccccc3N)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H09 compound treatment 0.269 0.034 0.49 0.296 0.0586 0.98 1.0395 0.9474 3121486 ChemDiv3_014243 COC(CNC1=Nc2ncccc2OC1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H10 compound treatment 0.328 0.093 1.33 0.326 0.0886 1.49 1.9922 0.9985 3121487 ChemDiv3_014244 COc1ccc2n3CN(CC4CCCO4)CN(Cc5ccccc5)c3nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H11 compound treatment 0.314 0.079 1.13 0.27 0.0326 0.55 1.186 0.9445 3039017 ChemDiv3_014245 CC1CCN(CC1)c2ccc(NC(=O)CCC(=O)O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H12 compound treatment 0.308 0.073 1.04 0.232 -0.00542 -0.09 0.6743 0.6431 3039018 ChemDiv3_014246 C(c1c[nH]c2ccccc12)c3nc(cs3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H13 compound treatment 0.335 0.1 1.43 0.3 0.0626 1.05 1.7545 0.9884 3039020 ChemDiv3_014247 Cc1ccc(o1)c2cc(nc(N)c2C#N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H14 compound treatment 0.272 0.037 0.53 0.262 0.0246 0.41 0.6663 0.9924 3039021 ChemDiv3_014248 CCN(C(=O)C)c1nc2c(s1)n(C(=O)C)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H15 compound treatment 0.311 0.076 1.09 0.309 0.0716 1.2 1.6185 0.9988 3039023 ChemDiv3_014249 CCn1cc(C(=O)OCC=C)c(=O)c2ccc(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H16 compound treatment 0.314 0.079 1.13 0.317 0.0796 1.34 1.7438 0.9966 3039024 ChemDiv3_014250 CSc1nc(N)nc2sc(C(=O)c3ccc(Cl)cc3)c(N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H17 compound treatment 0.283 0.048 0.69 0.303 0.0656 1.1 1.2641 0.9743 3039025 ChemDiv3_014251 O=C(CSc1nn2cnnc2s1)N(C3CCCCC3)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H18 compound treatment 0.318 0.083 1.19 0.284 0.0466 0.78 1.3926 0.9794 3039027 ChemDiv3_014252 CC(C)(CC(=O)O)CC(=O)Nn1c(=O)c2ccccc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H19 compound treatment 0.285 0.05 0.72 0.305 0.0676 1.13 1.3081 0.9753 3039028 ChemDiv3_014253 Cc1ccc2c(c1)sc3ncc(NC(=O)c4ccccc4)c(=O)n23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H20 compound treatment 0.281 0.046 0.66 0.255 0.0176 0.3 0.6742 0.9344 3121488 ChemDiv3_014254 CC(C)CC1C(=C(C)Nc2c(cnn12)C(=O)Nc3ccccc3)C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H21 compound treatment 0.301 0.066 0.94 0.277 0.0396 0.66 1.1376 0.9852 3039030 ChemDiv3_014255 CC(C)CC1=NC(N=C(O1)N2CCCCC2)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H22 compound treatment 0.231 -0.00397 -0.06 0.24 0.00258 0.04 -0.0095 -0.1331 3121489 ChemDiv3_014256 CC(CNC(=O)c1cccc(Nc2nc3ccccc3n4cnnc24)c1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H23 mock treatment 0.241 0.00603 0.09 0.237 -4.19E-4 -0.01 0.056 0.6473 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 H24 mock treatment 0.223 -0.012 -0.17 0.222 -0.0154 -0.26 -0.304 -0.9799 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I01 compound treatment 0.228 -0.00697 -0.1 0.249 0.0116 0.19 0.067 0.3066 3039032 ChemDiv3_014257 Clc1ccc(NC(=O)Cc2ccc(cc2)n3cccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I02 compound treatment 0.047 -0.188 -2.69 0.059 -0.178 -2.99 -4.0186 -0.9986 1291873 ChemDiv3_014258 CCc1ccc(cc1)C2=NC(C)(CC)NC(C2)c3cc(Cl)ccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I03 compound treatment 0.285 0.05 0.72 0.258 0.0206 0.35 0.7503 0.9442 3121490 ChemDiv3_014259 COC(=O)CN(c1ccc(cc1)C(C)C)S(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I04 compound treatment 0.253 0.018 0.26 0.276 0.0386 0.65 0.6403 0.9186 1487708 ChemDiv3_014260 COc1ccc(NC(=O)c2sc3nc(C)nc(N(C)c4ccc(cc4)C(C)C)c3c2C)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I05 compound treatment 0.292 0.057 0.82 0.279 0.0416 0.7 1.0703 0.997 3121491 ChemDiv3_014261 OC(=O)C(Cc1ccccc1)NS(=O)(=O)c2cccc3cccnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I06 compound treatment 0.267 0.032 0.46 0.328 0.0906 1.52 1.399 0.8811 1128308 ChemDiv3_014262 CCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NCc2ccccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I07 compound treatment 0.329 0.094 1.35 0.319 0.0816 1.37 1.9193 1.0 3121492 ChemDiv3_014263 CN(C)/C=C/c1onc(C)c1S(=O)(=O)NCCN2CCC(Cc3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I08 compound treatment 0.299 0.064 0.92 0.311 0.0736 1.23 1.5209 0.9892 3121493 ChemDiv3_014264 Cc1ccccc1CN2CCN(CC2)C3c4ccccc4-c5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I09 compound treatment 0.302 0.067 0.96 0.235 -0.00242 -0.04 0.6493 0.6766 3039037 ChemDiv3_014265 OC(=O)Cn1c(nc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I10 compound treatment 0.312 0.077 1.1 0.322 0.0846 1.42 1.7829 0.9922 1211799 ChemDiv3_014266 O=C(NCc1ccco1)c2oc(=O)c3ccccc3c2c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I11 compound treatment 0.266 0.031 0.44 0.303 0.0656 1.1 1.0922 0.9202 3039039 ChemDiv3_014267 CCOC(=O)c1cc(c2ccc(F)cc2)n(CCC(=O)Nc3nc4ccc(C)cc4s3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I12 compound treatment 0.315 0.08 1.14 0.277 0.0396 0.66 1.2792 0.9665 1692523 ChemDiv3_014268 COc1cc2CCN(C(C)c2cc1OC)C(=O)CCN3C(=O)C4C5CC(C=C5)C4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I13 compound treatment 0.254 0.019 0.27 0.274 0.0366 0.61 0.6266 0.933 3121673 ChemDiv3_014269 Brc1cnc2NC(=NS(=O)(=O)c2c1)CCC(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I14 compound treatment 0.281 0.046 0.66 0.296 0.0586 0.98 1.1608 0.981 3038955 ChemDiv3_014270 Cc1cc2c(=O)n(CC(=O)NCC(=O)N3CCCCC3)cnc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I15 compound treatment 0.302 0.067 0.96 0.264 0.0266 0.45 0.9934 0.9394 3038956 ChemDiv3_014271 CCOC(=O)c1cc(c2ccccc2)n(CCCC(=O)NCc3ccccc3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I16 compound treatment 0.277 0.042 0.6 0.281 0.0436 0.73 0.9423 0.9953 3038958 ChemDiv3_014272 C(=C/c1ccncc1)\c2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I17 compound treatment 0.267 0.032 0.46 0.296 0.0586 0.98 1.0192 0.9396 3038959 ChemDiv3_014273 CCC(Cc1ccccc1)NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I18 compound treatment 0.307 0.072 1.03 0.298 0.0606 1.02 1.4475 1.0 1222646 ChemDiv3_014274 Nc1ccc(Oc2ccc3C(=O)N(Cc4ccco4)C(=O)c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I19 compound treatment 0.282 0.047 0.67 0.298 0.0606 1.02 1.1947 0.9799 3038961 ChemDiv3_014275 O=c1ccc(n[nH]1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I20 compound treatment 0.224 -0.011 -0.16 0.261 0.0236 0.4 0.1689 0.3968 3038962 ChemDiv3_014276 COC(=O)c1c(N)scc1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I21 compound treatment 0.24 0.00503 0.07 0.243 0.00558 0.09 0.1171 0.9915 1455752 ChemDiv3_014277 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4)c12)C(=O)N5CCCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I22 compound treatment 0.237 0.00203 0.03 0.218 -0.0194 -0.33 -0.2099 -0.6415 3038964 ChemDiv3_014278 CC(Cn1ccnc1C)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I23 mock treatment 0.215 -0.02 -0.29 0.2 -0.0374 -0.63 -0.6461 -0.9364 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 I24 mock treatment 0.225 -0.00997 -0.14 0.215 -0.0224 -0.38 -0.3669 -0.9118 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J01 compound treatment 0.245 0.01 0.14 0.261 0.0236 0.4 0.3813 0.9058 3038966 ChemDiv3_014279 NC(CC(=O)O)c1cccc(O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J02 compound treatment 0.235 3.23E-5 0.0 0.225 -0.0124 -0.21 -0.1471 -0.7055 3121674 ChemDiv3_014280 COc1ccc(cc1)C2=NC(N=C(O2)c3ccccc3C)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J03 compound treatment 0.279 0.044 0.63 0.271 0.0336 0.56 0.8439 0.9985 1732489 ChemDiv3_014281 COc1cccc(Nc2ccc(cc2N)C(=O)O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J04 compound treatment 0.283 0.048 0.69 0.257 0.0196 0.33 0.7182 0.943 3121675 ChemDiv3_014282 Fc1ccccc1Cn2ccccc2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J05 compound treatment 0.309 0.074 1.06 0.289 0.0516 0.87 1.3609 0.995 3121676 ChemDiv3_014283 OC(=O)C1CN(Cc2ccc(F)cc2)C(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J06 compound treatment 0.293 0.058 0.83 0.33 0.0926 1.55 1.6857 0.9569 3038969 ChemDiv3_014284 CSc1nsc(SCC(=O)OC2CC(C)CCC2C(C)C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J07 compound treatment 0.267 0.032 0.46 0.247 0.00958 0.16 0.4377 0.9014 3121677 ChemDiv3_014285 OC(=O)CCSCc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J08 compound treatment 0.307 0.072 1.03 0.321 0.0836 1.4 1.7205 0.9885 3121678 ChemDiv3_014286 COc1ccc(cc1)C2N(CCCN2S(=O)(=O)c3ccc(C)cc3)C(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J09 compound treatment 0.243 0.00803 0.11 0.261 0.0236 0.4 0.3611 0.8762 3038971 ChemDiv3_014287 OC(=O)Cn1c-2c(CSc3ccc(Cl)cc23)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J10 compound treatment 0.298 0.063 0.9 0.303 0.0656 1.1 1.4158 0.9951 3121679 ChemDiv3_014288 CC1(C)CC(=O)C2=C(C1)NCN(CCCN3CCOCC3)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J11 compound treatment 0.284 0.049 0.7 0.289 0.0516 0.87 1.1081 0.9945 1032476 ChemDiv3_014289 CN1N=C(CC1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J12 compound treatment 0.098 -0.137 -1.96 0.115 -0.122 -2.05 -2.8382 -0.9997 1502309 ChemDiv3_014290 CC(=O)N1C2SC(=NC2(O)c3ccccc13)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J13 compound treatment 0.341 0.106 1.52 0.318 0.0806 1.35 2.0288 0.9984 3038974 ChemDiv3_014291 CCC(Sc1nnc2sc3ccccc3n12)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J14 compound treatment 0.323 0.088 1.26 0.297 0.0596 1.0 1.5975 0.9935 3121680 ChemDiv3_014292 Fc1cccc(Cn2n(Cc3cccc(F)c3)c(=O)n(c4cccc(Cl)c4)c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J15 compound treatment 0.319 0.084 1.2 0.282 0.0446 0.75 1.379 0.974 3038976 ChemDiv3_014293 CCn1cc(C(=O)OCc2ccccc2)c(=O)c3ccc(C)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J16 compound treatment 0.275 0.04 0.57 0.258 0.0206 0.35 0.6491 0.9707 3039041 ChemDiv3_014294 CSc1nc2[nH]c(=O)cc(O)c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J17 compound treatment 0.185 -0.05 -0.71 0.187 -0.0504 -0.85 -1.1038 -0.9965 3039042 ChemDiv3_014295 Oc1ccc(cc1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J18 compound treatment 0.275 0.04 0.57 0.295 0.0576 0.97 1.0883 0.9688 3039044 ChemDiv3_014296 COCCn1c(NN)nc2ccsc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J19 compound treatment 0.315 0.08 1.14 0.274 0.0366 0.61 1.2436 0.9574 3039045 ChemDiv3_014297 CCOC(=O)c1cc(NC(=O)c2ccccc2)c(=O)n3c4ccccc4oc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J20 compound treatment 0.258 0.023 0.33 0.305 0.0676 1.13 1.035 0.8763 3039047 ChemDiv3_014298 COC(=O)c1cc2ccc3OCN(Cc4ccccc4)Cc3c2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J21 compound treatment 0.279 0.044 0.63 0.269 0.0316 0.53 0.8202 0.9963 3039049 ChemDiv3_014299 N/C(=N\C1=NC(N=C(O1)c2cccnc2)(C(F)(F)F)C(F)(F)F)/Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J22 compound treatment 0.246 0.011 0.16 0.239 0.00158 0.03 0.1303 0.8146 3039050 ChemDiv3_014300 CCCOc1ccc(cc1)C(=O)Nc2c(NC)c3ccccc3oc2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J23 mock treatment 0.25 0.015 0.22 0.265 0.0276 0.46 0.4794 0.9392 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 J24 mock treatment 0.242 0.00703 0.1 0.222 -0.0154 -0.26 -0.1119 -0.4029 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K01 compound treatment 0.271 0.036 0.52 0.233 -0.00442 -0.07 0.312 0.5992 3039052 ChemDiv3_014301 O=C(Cc1ccc(cc1)n2cccc2)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K02 compound treatment 0.19 -0.045 -0.64 0.222 -0.0154 -0.26 -0.6378 -0.9199 1572441 ChemDiv3_014302 COC(=O)c1ccc(cc1)C2NC(CC(=N2)c3cccc(OC)c3)c4ccccc4O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K03 compound treatment 0.255 0.02 0.29 0.261 0.0236 0.4 0.4825 0.9874 3121681 ChemDiv3_014303 CCOC(=O)c1cc(c2ccc(OC)cc2)n(CCC(=O)N3CCc4ccccc34)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K04 compound treatment 0.254 0.019 0.27 0.271 0.0336 0.56 0.591 0.9443 1612615 ChemDiv3_014304 CCC(C)NC(=O)c1sc2nc(C)nc(N(C)c3ccc(cc3)C(C)C)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K05 compound treatment 0.275 0.04 0.57 0.306 0.0686 1.15 1.2188 0.948 3121682 ChemDiv3_014305 CCc1ccc(cc1)N(CC(=O)NC2CCCC2)S(=O)(=O)c3c(C)noc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K06 compound treatment 0.263 0.028 0.4 0.28 0.0426 0.71 0.7889 0.9627 1732890 ChemDiv3_014306 CCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NC2CCCCC2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K07 compound treatment 0.269 0.034 0.49 0.286 0.0486 0.82 0.9208 0.9696 3121683 ChemDiv3_014307 Clc1ccc(cc1)C2(C#N)N(Nc3ccccc32)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K08 compound treatment 0.283 0.048 0.69 0.273 0.0356 0.6 0.9081 0.9976 3121684 ChemDiv3_014308 Fc1ccccc1NC(=O)CCN2CCN(CC2)C3c4ccccc4-c5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K09 compound treatment 0.212 -0.023 -0.33 0.197 -0.0404 -0.68 -0.712 -0.9446 3039057 ChemDiv3_014309 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)N(C)Cc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K10 compound treatment 0.315 0.08 1.14 0.308 0.0706 1.18 1.6471 0.9999 3121685 ChemDiv3_014310 Fc1ccccc1NC(=O)CCn2c(=S)oc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K11 compound treatment 0.304 0.069 0.99 0.28 0.0426 0.71 1.2036 0.9874 3121686 ChemDiv3_014311 CCc1ccccc1NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCCC4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K12 compound treatment 0.294 0.059 0.84 0.29 0.0526 0.88 1.2211 0.9998 1689428 ChemDiv3_014312 Cc1ccc(cc1)S(=O)(=O)CCC(=O)Nc2nccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K13 compound treatment 0.251 0.016 0.23 0.289 0.0516 0.87 0.7743 0.8646 3039060 ChemDiv3_014313 CCOC(=O)c1ccc(n1C)S(=O)(=O)NC2CCCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K14 compound treatment 0.275 0.04 0.57 0.256 0.0186 0.31 0.6254 0.9592 3121687 ChemDiv3_014314 COC(=O)CNC(=O)c1cc2c(=O)oc3ccccc3c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K15 compound treatment 0.248 0.013 0.19 0.286 0.0486 0.82 0.7084 0.8469 3121688 ChemDiv3_014315 CCOC(=O)c1cc(c2ccc(C)cc2)n(CCCC(=O)Nc3cccc(CC)c3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K16 compound treatment 0.287 0.052 0.74 0.279 0.0416 0.7 1.0197 0.9995 3038992 ChemDiv3_014316 O=C(C/C=N/c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K17 compound treatment 0.304 0.069 0.99 0.284 0.0466 0.78 1.251 0.9933 3121689 ChemDiv3_014317 CCOC(=O)c1[nH]c(C)c(C(=O)NCCc2ccc(OC)c(OC)c2)c1CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K18 compound treatment 0.29 0.055 0.79 0.261 0.0236 0.4 0.8365 0.9494 3121690 ChemDiv3_014318 OC(=O)c1ccc(o1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K19 compound treatment 0.291 0.056 0.8 0.234 -0.00342 -0.06 0.5261 0.6548 3121691 ChemDiv3_014319 O=c1ccc(n[nH]1)c2ccc(s2)S(=O)(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K20 compound treatment 0.242 0.00703 0.1 0.259 0.0216 0.36 0.3272 0.8705 1286152 ChemDiv3_014320 CC(=O)Nc1ccc(cc1)N2S(=O)(=O)c3ccccc3S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K21 compound treatment 0.255 0.02 0.29 0.267 0.0296 0.5 0.5537 0.9659 1727899 ChemDiv3_014321 COc1cccc(NC(=O)c2sc3ncnc(N4CCc5ccccc5C4)c3c2C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K22 compound treatment 0.23 -0.00497 -0.07 0.244 0.00658 0.11 0.0279 0.2121 3037892 ChemDiv3_014322 CC1=CC=CC2=NC(=O)CC(C)(N12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K23 mock treatment 0.253 0.018 0.26 0.253 0.0156 0.26 0.3673 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 K24 mock treatment 0.211 -0.024 -0.34 0.22 -0.0174 -0.29 -0.4491 -0.9969 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L01 compound treatment 0.277 0.042 0.6 0.272 0.0346 0.58 0.8355 0.9998 3121692 ChemDiv3_014323 FC(F)(F)C1=CC(=O)c2cccc3c(NC4CCCCC4)ccc1c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L02 compound treatment 0.245 0.01 0.14 0.296 0.0586 0.98 0.7967 0.8018 3037895 ChemDiv3_014324 Cc1ccc(cc1)C2=NC(N=C(O2)c3ccco3)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L03 compound treatment 0.23 -0.00497 -0.07 0.235 -0.00242 -0.04 -0.079 -0.9648 3121693 ChemDiv3_014325 Nc1cc(ccc1NCCCN2CCOCC2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L04 compound treatment 0.277 0.042 0.6 0.255 0.0176 0.3 0.6338 0.9463 3037896 ChemDiv3_014326 Clc1ccc(cc1)C(=O)OCC2CC(=NO2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L05 compound treatment 0.263 0.028 0.4 0.267 0.0296 0.5 0.6346 0.9944 3121694 ChemDiv3_014327 COc1ccc(cc1)C(N)CCc2ccc(C)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L06 compound treatment 0.299 0.064 0.92 0.309 0.0716 1.2 1.4972 0.991 3121695 ChemDiv3_014328 CC1(C)CC(=O)c2cc(NC(=O)c3ccccc3)c(=O)oc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L07 compound treatment 0.299 0.064 0.92 0.295 0.0576 0.97 1.331 0.9996 3037899 ChemDiv3_014329 OC(=O)CSCc1ccc(F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L08 compound treatment 0.29 0.055 0.79 0.309 0.0716 1.2 1.4061 0.979 3037900 ChemDiv3_014330 Cc1cc(C)nc(n1)n2cc3c(=O)[nH]c(=S)nc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L09 compound treatment 0.251 0.016 0.23 0.263 0.0256 0.43 0.4657 0.9569 3121877 ChemDiv3_014331 COC(=O)CC1Oc2ccccc2N(Cc3ccc(C)cc3)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L10 compound treatment 0.299 0.064 0.92 0.282 0.0446 0.75 1.1767 0.995 3121878 ChemDiv3_014332 Cc1ccc(NC2=NC(c3ccccc3)n4c(N2)nc(C)cc4=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L11 compound treatment 0.067 -0.168 -2.4 0.065 -0.172 -2.89 -3.7452 -0.9957 1689444 ChemDiv3_014333 Clc1ccc(CNc2nc3ccccc3[nH]2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L12 compound treatment 0.076 -0.159 -2.27 0.088 -0.149 -2.51 -3.3812 -0.9988 1308505 ChemDiv3_014334 CC(=O)n1c2sc(N)nc2c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L13 compound treatment 0.304 0.069 0.99 0.295 0.0576 0.97 1.3816 0.9999 3121879 ChemDiv3_014335 O=C(CSc1nnc2sc3ccccc3n12)N4N=CCC4c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L14 compound treatment 0.258 0.023 0.33 0.3 0.0626 1.05 0.9757 0.8863 3037941 ChemDiv3_014336 Cc1n[nH]c(NC2=CC(=O)CC(C2)c3ccc(C)cc3)c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L15 compound treatment 0.277 0.042 0.6 0.29 0.0526 0.88 1.0492 0.9825 3121880 ChemDiv3_014337 Cc1ccccc1NS(=O)(=O)c2ccc3n(C)c(=O)n(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L16 compound treatment 0.303 0.068 0.97 0.286 0.0486 0.82 1.2647 0.9961 3121881 ChemDiv3_014338 O=C(N1CCCCC1)/C(=C/2\C(=O)Nc3ccccc23)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L17 compound treatment 0.311 0.076 1.09 0.314 0.0766 1.29 1.6779 0.9965 3037943 ChemDiv3_014339 CC(C)CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)Nc4ccc(cc4)S(=O)(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L18 compound treatment 0.275 0.04 0.57 0.265 0.0276 0.46 0.7322 0.9944 3121882 ChemDiv3_014340 CC(C)Cn1c(=O)c2sccc2n3c(CCCC(=O)N(C)Cc4ccco4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L19 compound treatment 0.256 0.021 0.3 0.241 0.00358 0.06 0.2552 0.8319 3121883 ChemDiv3_014341 COc1ccc2[nH]cc(CCNC(=O)NC3(C[C@H]4C[C@@H]5C[C@H](C4)C3)C5)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L20 compound treatment 0.298 0.063 0.9 0.256 0.0186 0.31 0.858 0.8994 3037946 ChemDiv3_014342 Cc1cccc(c1)N2C(=O)NC3CC2(C)Oc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L21 compound treatment 0.308 0.073 1.04 0.309 0.0716 1.2 1.5882 0.9976 3121884 ChemDiv3_014343 FC(F)(F)C1(C2CC(C=C2)N1S(=O)(=O)c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L22 compound treatment 0.254 0.019 0.27 0.28 0.0426 0.71 0.6978 0.9125 3037948 ChemDiv3_014344 CCOC(=O)CC(=O)Nc1c(NC)c2ccccc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L23 mock treatment 0.256 0.021 0.3 0.272 0.0346 0.58 0.6231 0.9532 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 L24 mock treatment 0.212 -0.023 -0.33 0.236 -0.00142 -0.02 -0.2491 -0.7564 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M01 compound treatment 0.275 0.04 0.57 0.277 0.0396 0.66 0.8746 0.9973 3121885 ChemDiv3_014345 Cc1n[nH]c(C)c1S(=O)(=O)N(CC(=O)O)c2cc(C)cc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M02 compound treatment 0.274 0.039 0.56 0.286 0.0486 0.82 0.9713 0.9829 1647178 ChemDiv3_014346 CC(C)C1(C)NC(CC(=N1)c2ccc3OCOc3c2)c4ccccc4O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M03 compound treatment 0.254 0.019 0.27 0.266 0.0286 0.48 0.5317 0.964 3121886 ChemDiv3_014347 CC12CC(C)(C)NC(=S)N2C(C(=O)O1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M04 compound treatment 0.311 0.076 1.09 0.265 0.0276 0.46 1.0963 0.9276 1697357 ChemDiv3_014348 Fc1ccc(cc1)S(=O)(=O)NC(Cc2ccccc2)C(=O)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M05 compound treatment 0.274 0.039 0.56 0.229 -0.00842 -0.14 0.2949 0.512 3037952 ChemDiv3_014349 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCCC(C3)C(=O)NN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M06 compound treatment 0.288 0.053 0.76 0.289 0.0516 0.87 1.1485 0.9978 3121887 ChemDiv3_014350 O=C/1Nc2ccccc2\C1=C\C3CCC=CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M07 compound treatment 0.296 0.061 0.87 0.282 0.0446 0.75 1.1464 0.9971 3121888 ChemDiv3_014351 CCOC(=O)c1cc(c2ccccc2)n(CCC(=O)N(C)C3CCCCC3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M08 compound treatment 0.243 0.00803 0.11 0.191 -0.0464 -0.78 -0.4697 -0.5964 3037954 ChemDiv3_014352 FC(F)(F)c1cccc(NC(=O)CCN2CCN(CC2)C3c4ccccc4-c5ccccc35)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M09 compound treatment 0.263 0.028 0.4 0.283 0.0456 0.77 0.8245 0.9546 3121889 ChemDiv3_014353 Cn1cnc(c1)S(=O)(=O)Nc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M10 compound treatment 0.267 0.032 0.46 0.26 0.0226 0.38 0.592 0.9956 3121890 ChemDiv3_014354 CCc1ccccc1N(C)C(=O)CCn2c(=S)oc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M11 compound treatment 0.287 0.052 0.74 0.276 0.0386 0.65 0.9841 0.9976 3121891 ChemDiv3_014355 O=C(Nc1ccc(cc1)C(=O)N2CCCCC2)c3ccc(=O)[nH]c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M12 compound treatment 0.291 0.056 0.8 0.264 0.0266 0.45 0.8822 0.9618 1616530 ChemDiv3_014356 CCOc1ccc(OCC)c(NC(=O)CCS(=O)(=O)c2ccc(C)cc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M13 compound treatment 0.29 0.055 0.79 0.281 0.0436 0.73 1.0738 0.9993 3121892 ChemDiv3_014357 COC(=O)c1ccc(n1C)S(=O)(=O)NCc2cccc(OC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M14 compound treatment 0.285 0.05 0.72 0.288 0.0506 0.85 1.1063 0.9964 1631137 ChemDiv3_014358 COC(=O)CNC(=O)c1nn(c2ccc(OC)cc2OC)c(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M15 compound treatment 0.278 0.043 0.62 0.27 0.0326 0.55 0.8219 0.9983 3121893 ChemDiv3_014359 CCOC(=O)c1cc(c2ccccc2)n(CCCC(=O)N3CCCCC3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M16 compound treatment 0.318 0.083 1.19 0.293 0.0556 0.93 1.4994 0.9929 1003750 ChemDiv3_014360 COc1ccc(CC(=O)O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M17 compound treatment 0.284 0.049 0.7 0.258 0.0206 0.35 0.7402 0.9468 3121894 ChemDiv3_014361 O=c1ccc2cc(ccc2[nH]1)S(=O)(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M18 compound treatment 0.267 0.032 0.46 0.279 0.0416 0.7 0.8175 0.9792 1732260 ChemDiv3_014362 NC(=O)C1CCN(CC1)C(=O)C2C(C3CCC2C3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M19 compound treatment 0.277 0.042 0.6 0.267 0.0296 0.5 0.7762 0.9955 3121895 ChemDiv3_014363 COc1ccc(CCC(=O)Nc2ccc(cc2)c3noc(CCc4ccccc4)n3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M20 compound treatment 0.284 0.049 0.7 0.24 0.00258 0.04 0.5266 0.7493 1644077 ChemDiv3_014364 CC(C)(C)c1cc([nH]n1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M21 compound treatment 0.271 0.036 0.52 0.262 0.0246 0.41 0.6562 0.9939 3121896 ChemDiv3_014365 CC(C)CC1NC(CC(=N1)c2ccc(C)cc2)c3ccccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M22 compound treatment 0.263 0.028 0.4 0.287 0.0496 0.83 0.872 0.944 3038008 ChemDiv3_014366 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)O)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M23 mock treatment 0.27 0.035 0.5 0.241 0.00358 0.06 0.3968 0.7863 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 M24 mock treatment 0.221 -0.014 -0.2 0.254 0.0166 0.28 0.0555 0.162 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N01 compound treatment 0.156 -0.079 -1.13 0.153 -0.0844 -1.42 -1.8006 -0.9937 1671367 ChemDiv3_014367 NNc1ccc2c(Cl)cc(Cl)c(O)c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N02 compound treatment 0.279 0.044 0.63 0.26 0.0226 0.38 0.7133 0.9705 3121897 ChemDiv3_014368 CCOC(=O)c1ccc(cc1)N2C(=O)NC(C3=C2CC(C)(C)CC3=O)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N03 compound treatment 0.249 0.014 0.2 0.279 0.0416 0.7 0.6354 0.875 3038011 ChemDiv3_014369 OC(=O)CCN1C(=O)CC2(CCCCC2)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N04 compound treatment 0.259 0.024 0.34 0.299 0.0616 1.03 0.9739 0.8941 3038012 ChemDiv3_014370 Nc1ncnc2n(CCN3CCCCC3)cnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N05 compound treatment 0.286 0.051 0.73 0.283 0.0456 0.77 1.0571 0.9997 3121898 ChemDiv3_014371 CCC(C)N1C(CCC1=O)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N06 compound treatment 0.282 0.047 0.67 0.272 0.0346 0.58 0.8861 0.9973 3121899 ChemDiv3_014372 Nc1ccccc1NC(=O)c2nc3ccccc3nc2C(O)C(O)CO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N07 compound treatment 0.269 0.034 0.49 0.269 0.0316 0.53 0.719 0.9991 3038015 ChemDiv3_014373 OC(=O)C1CN(C2CCCC2)C(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N08 compound treatment 0.29 0.055 0.79 0.305 0.0676 1.13 1.3587 0.9841 3121900 ChemDiv3_014374 CCOC(=O)C1C(NC(=NC1=O)N2CCc3ccccc23)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N09 compound treatment 0.285 0.05 0.72 0.303 0.0656 1.1 1.2844 0.9783 3038017 ChemDiv3_014375 OC(=O)Cn1cc2CCCCc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N10 compound treatment 0.324 0.089 1.27 0.308 0.0706 1.18 1.7381 0.9993 3121901 ChemDiv3_014376 Cc1nc2ccccc2c3N=C(CC(=O)c13)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N11 compound treatment 0.198 -0.037 -0.53 0.177 -0.0604 -1.01 -1.091 -0.9539 1871098 ChemDiv3_014377 COc1ccc(cc1)C2C3=C(Nc4[nH]c(=O)[nH]c(=O)c24)c5ccccc5C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N12 compound treatment 0.292 0.057 0.82 0.276 0.0386 0.65 1.0347 0.9935 3121902 ChemDiv3_014378 CC(=O)n1c2sc(C)nc2c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N13 compound treatment 0.321 0.086 1.23 0.268 0.0306 0.51 1.2331 0.9248 3121903 ChemDiv3_014379 COc1cc2CCN(Cc2cc1OC)C(=O)CSc3nnc4ccc5ccccc5n34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N14 compound treatment 0.27 0.035 0.5 0.239 0.00158 0.03 0.3731 0.7435 3038019 ChemDiv3_014380 CSc1nc(N)nc2sc(C(=O)C3(CC4CC5CC(C4)C3)C5)c(N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N15 compound treatment 0.299 0.064 0.92 0.292 0.0546 0.92 1.2954 1.0 3122086 ChemDiv3_014381 Cn1c(=O)n(C)c2cc(ccc12)S(=O)(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N16 compound treatment 0.307 0.072 1.03 0.318 0.0806 1.35 1.6849 0.991 3038075 ChemDiv3_014382 Fc1ccc(cc1)S(=O)(=O)N2CCCCC2C(=O)OCc3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N17 compound treatment 0.315 0.08 1.14 0.27 0.0326 0.55 1.1961 0.9428 3038077 ChemDiv3_014383 CCc1ccc2oc(nc2c1)c3cc(N)cc(C)c3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N18 compound treatment 0.281 0.046 0.66 0.299 0.0616 1.03 1.1964 0.9763 3122087 ChemDiv3_014384 O=c1[nH]ccn(c2ccccc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N19 compound treatment 0.257 0.022 0.32 0.291 0.0536 0.9 0.8587 0.9012 3122088 ChemDiv3_014385 NC1=NC2(CCN(Cc3ccccc3)CC2)n4c(N1)nc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N20 compound treatment 0.295 0.06 0.86 0.312 0.0746 1.25 1.4923 0.9831 3038079 ChemDiv3_014386 NC1=NC(N(C(=N1)N)c2ccc(F)c(Cl)c2)c3ccccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N21 compound treatment 0.286 0.051 0.73 0.267 0.0296 0.5 0.8672 0.9824 3122089 ChemDiv3_014387 FC(F)(F)C1(NN(C(=N1)c2cccnc2)c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N22 compound treatment 0.267 0.032 0.46 0.286 0.0486 0.82 0.9005 0.9628 3038081 ChemDiv3_014388 CNc1c(NC(=O)c2cccc(F)c2)c(=O)oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N23 mock treatment 0.242 0.00703 0.1 0.254 0.0166 0.28 0.2679 0.9054 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 N24 mock treatment 0.237 0.00203 0.03 0.267 0.0296 0.5 0.3716 0.7472 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O01 compound treatment 0.222 -0.013 -0.19 0.248 0.0106 0.18 -0.0056 -0.0218 3122090 ChemDiv3_014389 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N(C)c3ccc(C)cc3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O02 compound treatment 0.275 0.04 0.57 0.24 0.00258 0.04 0.4355 0.7584 3122091 ChemDiv3_014390 CCOc1ccc(cc1)C2=NC3(CCN(CC3)C(C)C)NC(C2)c4cc(Cl)ccc4O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O03 compound treatment 0.245 0.01 0.14 0.253 0.0156 0.26 0.2864 0.9601 3038083 ChemDiv3_014391 OC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O04 compound treatment 0.268 0.033 0.47 0.267 0.0296 0.5 0.6852 0.9997 3122092 ChemDiv3_014392 CC1CCCCC1NC(=O)c2cccc(NS(=O)(=O)c3ccc(Br)cc3)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O05 compound treatment 0.248 0.013 0.19 0.265 0.0276 0.46 0.4591 0.9201 3038085 ChemDiv3_014393 O=C(NC1CCCCC1)C2CCCN2S(=O)(=O)c3ccc4NC(=O)CCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O06 compound treatment 0.16 -0.075 -1.07 0.161 -0.0764 -1.28 -1.6652 -0.996 3122093 ChemDiv3_014394 O=C/1Nc2ccccc2\C1=C\c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O07 compound treatment 0.298 0.063 0.9 0.255 0.0176 0.3 0.8462 0.892 3038087 ChemDiv3_014395 CN(C)/C=C/c1onc(C)c1S(=O)(=O)N2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O08 compound treatment 0.246 0.011 0.16 0.269 0.0316 0.53 0.4864 0.8795 1667350 ChemDiv3_014396 Cc1ccccc1CN2CCN(CC2)C(=O)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O09 compound treatment 0.252 0.017 0.24 0.254 0.0166 0.28 0.369 0.9978 3038090 ChemDiv3_014397 Cc1ccc(NS(=O)(=O)c2cn(C)cn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O10 compound treatment 0.266 0.031 0.44 0.232 -0.00542 -0.09 0.2495 0.5508 1501444 ChemDiv3_014398 O=C(NC1CCCC1)C2CCCN2C(=O)OCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O11 compound treatment 0.262 0.027 0.39 0.239 0.00158 0.03 0.2922 0.7539 3122094 ChemDiv3_014399 CC1CC(C)CN(C1)C(=O)c2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O12 compound treatment 0.293 0.058 0.83 0.253 0.0156 0.26 0.7719 0.8869 3038091 ChemDiv3_014400 CCc1ccc(NC(=O)CCS(=O)(=O)c2ccc(Br)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O13 compound treatment 0.227 -0.00797 -0.11 0.217 -0.0204 -0.34 -0.3229 -0.8941 3122095 ChemDiv3_014401 Nc1ncc(Br)cc1S(=O)(=O)NCc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O14 compound treatment 0.264 0.029 0.42 0.261 0.0236 0.4 0.5735 0.9997 1512154 ChemDiv3_014402 CCCCN(CC)C(=O)c1nn(c2ccc(OC)cc2)c(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O15 compound treatment 0.248 0.013 0.19 0.231 -0.00642 -0.11 0.0556 0.2584 3122096 ChemDiv3_014403 CN(C)/C=C/c1onc(C)c1S(=O)(=O)Nc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O16 compound treatment 0.239 0.00403 0.06 0.263 0.0256 0.43 0.3444 0.795 1032481 ChemDiv3_014404 CCCCC(=O)c1ccc(O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O17 compound treatment 0.282 0.047 0.67 0.276 0.0386 0.65 0.9336 0.9998 3122097 ChemDiv3_014405 Cc1cc(NS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O18 compound treatment 0.136 -0.099 -1.42 0.184 -0.0534 -0.9 -1.635 -0.9757 1468252 ChemDiv3_014406 CCOC(=O)c1cc(c2ccccc2)n(c1C)c3ccc(cc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O19 compound treatment 0.224 -0.011 -0.16 0.246 0.00858 0.14 -0.0091 -0.0427 3122098 ChemDiv3_014407 Brc1ccc(OCc2nc(no2)c3ccc(NC(=O)c4cccnc4)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O20 compound treatment 0.22 -0.015 -0.21 0.218 -0.0194 -0.33 -0.3819 -0.9792 1591637 ChemDiv3_014408 OC(=O)c1n[nH]c2CCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O21 compound treatment 0.225 -0.00997 -0.14 0.153 -0.0844 -1.42 -1.1027 -0.7743 1788098 ChemDiv3_014409 CC(C)C1NC(CC(=N1)c2ccc(C)cc2)c3ccccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O22 compound treatment 0.244 0.00903 0.13 0.244 0.00658 0.11 0.1695 0.997 3037969 ChemDiv3_014410 OC(=O)c1c[nH]nc1c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O23 mock treatment 0.228 -0.00697 -0.1 0.251 0.0136 0.23 0.0907 0.3646 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 O24 mock treatment 0.214 -0.021 -0.3 0.231 -0.00642 -0.11 -0.2883 -0.9045 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P01 compound treatment 0.231 -0.00397 -0.06 0.254 0.0166 0.28 0.1566 0.5515 1024926 ChemDiv3_014411 C1CN(CCN1)C(c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P02 compound treatment 0.261 0.026 0.37 0.231 -0.00642 -0.11 0.1871 0.4827 3122099 ChemDiv3_014412 CC(N1C(=NC(C2=C1CC(C)(C)CC2=O)(C(F)(F)F)C(F)(F)F)C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P03 compound treatment 0.247 0.012 0.17 0.253 0.0156 0.26 0.3066 0.9794 3038022 ChemDiv3_014413 OC(=O)CNC(=S)N(Cc1cccs1)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P04 compound treatment 0.252 0.017 0.24 0.275 0.0376 0.63 0.6183 0.9144 3122100 ChemDiv3_014414 Cc1cc(=O)oc2cc(OCC3CC(=NO3)c4ccccc4)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P05 compound treatment 0.263 0.028 0.4 0.269 0.0316 0.53 0.6583 0.9905 1518015 ChemDiv3_014415 Cc1ccc(cc1C)N2CC(CC2=O)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P06 compound treatment 0.236 0.00103 0.01 0.26 0.0226 0.38 0.2784 0.7341 1048613 ChemDiv3_014416 Oc1c(O)c(CN2CCOCC2)ccc1CN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P07 compound treatment 0.256 0.021 0.3 0.278 0.0406 0.68 0.6943 0.9325 3122101 ChemDiv3_014417 OC(=O)C1CN(CCc2ccccc2)C(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P08 compound treatment 0.243 0.00803 0.11 0.286 0.0486 0.82 0.6578 0.7989 3038025 ChemDiv3_014418 Nc1nc(Nc2ccccc2)c3C(=O)CC(Cc3n1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P09 compound treatment 0.272 0.037 0.53 0.245 0.00758 0.13 0.4645 0.8527 1459526 ChemDiv3_014419 Cc1nc2cc(ccc2n1c3ccc(Br)cc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P10 compound treatment 0.234 -9.68E-4 -0.01 0.215 -0.0224 -0.38 -0.2759 -0.7326 3122102 ChemDiv3_014420 Cc1cc(C)nc(NC2=NCN(Cc3ccccc3)CN2Cc4ccccc4)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P11 compound treatment 0.25 0.015 0.22 0.263 0.0256 0.43 0.4556 0.9489 3038027 ChemDiv3_014421 CSC1=N/C(=C\c2c(C)nn(c2Cl)c3ccccc3)/C(=O)S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P12 compound treatment 0.292 0.057 0.82 0.296 0.0586 0.98 1.2721 0.9957 3122103 ChemDiv3_014422 CC(=O)n1c2sc(nc2c3ccccc13)c4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P13 compound treatment 0.287 0.052 0.74 0.27 0.0326 0.55 0.9129 0.9885 3038029 ChemDiv3_014423 CC(C1CC(=O)N(Cc2ccco2)C1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P14 compound treatment 0.186 -0.049 -0.7 0.193 -0.0444 -0.75 -1.0224 -0.9995 3122104 ChemDiv3_014424 Cc1ccc(SCC2=NNC(=O)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P15 compound treatment 0.249 0.014 0.2 0.272 0.0346 0.58 0.5523 0.8994 3122105 ChemDiv3_014425 Oc1ccc(Cl)cc1C(CC(=O)N2CCCCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P16 compound treatment 0.287 0.052 0.74 0.268 0.0306 0.51 0.8892 0.9835 3038032 ChemDiv3_014426 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P17 compound treatment 0.282 0.047 0.67 0.298 0.0606 1.02 1.1947 0.9799 1174453 ChemDiv3_014427 CC(=O)Nc1ccc(NC2SC(=O)NC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P18 compound treatment 0.199 -0.036 -0.51 0.216 -0.0214 -0.36 -0.618 -0.9846 3038034 ChemDiv3_014428 Cc1ccc(cc1)c2n[nH]c3NC4=C(C(c23)c5ccccc5)C(=O)CC(C)(C)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P19 compound treatment 0.278 0.043 0.62 0.296 0.0586 0.98 1.1305 0.9746 3122106 ChemDiv3_014429 CC1CC(=O)C2=C(C1)Nc3ncnn3C2c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P20 compound treatment 0.047 -0.188 -2.69 0.05 -0.187 -3.15 -4.1255 -0.9969 3122107 ChemDiv3_014430 Cc1cc(C)cc(c1)N2C(N=C(N)N=C2N)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P21 compound treatment 0.276 0.041 0.59 0.292 0.0546 0.92 1.0628 0.9768 3038092 ChemDiv3_014431 CC1=CC2=NC(N=C(C)N2C=C1)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P22 compound treatment 0.298 0.063 0.9 0.29 0.0526 0.88 1.2616 0.9999 3122108 ChemDiv3_014432 CCNc1c(NC(=O)CC2(CC3CC4CC(C3)C2)C4)c(=O)oc5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P23 mock treatment 0.29 0.055 0.79 0.285 0.0476 0.8 1.1213 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2041 P24 mock treatment 0.203 -0.032 -0.46 0.228 -0.00942 -0.16 -0.4351 -0.8993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A01 compound treatment 0.251 0.0162 0.23 0.203 -0.0309 -0.52 -0.2034 -0.3582 3122109 ChemDiv3_014433 Oc1c(NC(=O)CC2(CC3CC4CC(C3)C2)C4)c(=O)oc5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A02 compound treatment 0.225 -0.00984 -0.14 0.237 0.00309 0.05 -0.0628 -0.4188 3038095 ChemDiv3_014434 COc1cc2CCN(C(c3ccccc3)c2cc1OC)C(=O)c4oc5ccccc5c4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A03 compound treatment 0.224 -0.0108 -0.16 0.238 0.00409 0.07 -0.0611 -0.3601 3122292 ChemDiv3_014435 OC(=O)c1ccc(Cn2nc(ccc2=O)N3CCCCC3)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A04 compound treatment 0.26 0.0252 0.36 0.224 -0.00991 -0.17 0.1369 0.3453 3038097 ChemDiv3_014436 C(Nc1noc2ccccc12)Nc3noc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A05 compound treatment 0.21 -0.0248 -0.36 0.224 -0.00991 -0.17 -0.3688 -0.9401 3122293 ChemDiv3_014437 Cc1ccc(cc1)S(=O)(=O)c2cc3cc(ccc3oc2=O)C(=O)Nc4ccc(C)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A06 compound treatment 0.235 1.56E-4 0.0 0.217 -0.0169 -0.28 -0.1991 -0.7015 3038099 ChemDiv3_014438 COc1ccc(NC(=O)C(C)Oc2ccc3c(cc(=O)oc3c2)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A07 compound treatment 0.239 0.00416 0.06 0.218 -0.0159 -0.27 -0.1467 -0.5365 3122294 ChemDiv3_014439 CCNc1cc(N(C)C)c2noc3-c4ccccc4C(=O)c1c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A08 compound treatment 0.232 -0.00284 -0.04 0.216 -0.0179 -0.3 -0.2413 -0.7956 3122295 ChemDiv3_014440 Cc1nnc(SCC(=O)NC2CCCCC2)nc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A09 compound treatment 0.235 1.56E-4 0.0 0.206 -0.0279 -0.47 -0.3296 -0.7037 3038100 ChemDiv3_014441 CN(C)c1nc2cc3c(C)c(oc3cc2s1)C(=O)N4CCC(CC4)C(=O)N5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A10 compound treatment 0.224 -0.0108 -0.16 0.237 0.00309 0.05 -0.073 -0.4461 3122296 ChemDiv3_014442 CCCCC(CC)CN1CC(=O)C(=C1N)c2nc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A11 compound treatment 0.202 -0.0328 -0.47 0.236 0.00209 0.04 -0.3073 -0.6524 3122297 ChemDiv3_014443 CCOC(=O)C1=C(C)NC(CS1)C(=O)NCCCN2CC(C)CC(C)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A12 compound treatment 0.245 0.0102 0.15 0.251 0.0171 0.29 0.3056 0.9503 1492617 ChemDiv3_014444 O=C(Nc1ccc(cc1)c2ccccc2)C3=C4Nc5ccccc5N4CCC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A13 compound treatment 0.234 -8.44E-4 -0.01 0.236 0.00209 0.04 0.0163 0.4391 3122298 ChemDiv3_014445 CCCN(CCC)C(=O)CSc1nc2cccnc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A14 compound treatment 0.216 -0.0188 -0.27 0.215 -0.0189 -0.32 -0.415 -0.9967 3038102 ChemDiv3_014446 CCOc1nc2n(C)cnc2c(=O)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A15 compound treatment 0.244 0.00916 0.13 0.223 -0.0109 -0.18 -0.0368 -0.1636 3122299 ChemDiv3_014447 CCOC(=O)N1CCC(CC1)Nc2nc3ccc(Cl)cc3n4cnnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A16 compound treatment 0.21 -0.0248 -0.36 0.201 -0.0329 -0.55 -0.6418 -0.9773 3122300 ChemDiv3_014448 O=C(NCc1nc(no1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A17 compound treatment 0.226 -0.00884 -0.13 0.224 -0.00991 -0.17 -0.207 -0.9909 3038104 ChemDiv3_014449 CCn1c(cc2oc3ccccc3c12)C(=O)NCCCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A18 compound treatment 0.185 -0.0498 -0.71 0.202 -0.0319 -0.54 -0.8828 -0.9901 3122301 ChemDiv3_014450 CCOc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3CCCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A19 compound treatment 0.235 1.56E-4 0.0 0.214 -0.0199 -0.33 -0.2347 -0.7024 3038105 ChemDiv3_014451 COCc1nc2cc(C)ccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A20 compound treatment 0.226 -0.00884 -0.13 0.215 -0.0189 -0.32 -0.3138 -0.9187 3122302 ChemDiv3_014452 FC(F)(F)c1cccc(c1)N2C3CS(=O)(=O)CC3SC2=N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A21 compound treatment 0.227 -0.00784 -0.11 0.211 -0.0229 -0.38 -0.3512 -0.8769 3038415 ChemDiv3_014453 Oc1nc2ccccc2cc1CN(C(=O)c3cccc(Cl)c3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A22 compound treatment 0.228 -0.00684 -0.1 0.236 0.00209 0.04 -0.0444 -0.4266 3038417 ChemDiv3_014454 COc1cccc(c1)c2coc3cc4oc(=O)cc(C)c4cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A23 mock treatment 0.21 -0.0248 -0.36 0.221 -0.0129 -0.22 -0.4044 -0.9718 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 A24 mock treatment 0.231 -0.00384 -0.05 0.235 0.00109 0.02 -0.0259 -0.4468 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B01 compound treatment 0.229 -0.00584 -0.08 0.225 -0.00891 -0.15 -0.1648 -0.9623 3122303 ChemDiv3_014455 Cc1c(CC(=O)O)c(=O)oc2c(C)c3occ(c4ccc(Br)cc4)c3cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B02 compound treatment 0.221 -0.0138 -0.2 0.207 -0.0269 -0.45 -0.4593 -0.9315 3122304 ChemDiv3_014456 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B03 compound treatment 0.243 0.00816 0.12 0.213 -0.0209 -0.35 -0.1656 -0.4479 3038455 ChemDiv3_014457 COc1cccc(CN2COc3ccc4c(cc(=O)oc4c3C2)c5ccccc5)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B04 compound treatment 0.244 0.00916 0.13 0.245 0.0111 0.19 0.2243 0.9852 3122305 ChemDiv3_014458 CN(Cc1csc(C)c1C)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B05 compound treatment 0.256 0.0212 0.3 0.256 0.0221 0.37 0.4762 0.9949 3038457 ChemDiv3_014459 Cc1ccc(cc1)n2nnc3c(sc4nc(C)cc(C)c43)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B06 compound treatment 0.213 -0.0218 -0.31 0.258 0.0241 0.4 0.065 0.1272 3122306 ChemDiv3_014460 OC(=O)CSCc1csc2CCCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B07 compound treatment 0.215 -0.0198 -0.28 0.257 0.0231 0.39 0.0734 0.1527 3038459 ChemDiv3_014461 CN(Cc1ccco1)Cc2cc(=O)oc3cc(C)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B08 compound treatment 0.242 0.00716 0.1 0.263 0.0291 0.49 0.4177 0.8371 3122307 ChemDiv3_014462 CCOC(=O)CC1NCCc2cc(OCC)c(OCC)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B09 compound treatment 0.245 0.0102 0.15 0.219 -0.0149 -0.25 -0.0742 -0.2564 1229726 ChemDiv3_014463 CC(C)N(C(=O)CSCc1nc2ccccc2[nH]1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B10 compound treatment 0.247 0.0122 0.17 0.204 -0.0299 -0.5 -0.232 -0.4367 3038462 ChemDiv3_014464 NC(=O)c1cc(cs1)S(=O)(=O)NC2CCCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B11 compound treatment 0.242 0.00716 0.1 0.239 0.00509 0.09 0.1328 0.996 3122308 ChemDiv3_014465 CC(C(=O)N1CCc2ccccc12)n3sc4ccccc4c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B12 compound treatment 0.257 0.0222 0.32 0.237 0.00309 0.05 0.2608 0.8121 3038466 ChemDiv3_014466 CCc1ccccc1NC(=O)CCNS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B13 compound treatment 0.214 -0.0208 -0.3 0.247 0.0131 0.22 -0.0554 -0.1496 3122309 ChemDiv3_014467 CC(C)C(=O)Nc1nn2c(nnc2s1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B14 compound treatment 0.255 0.0202 0.29 0.246 0.0121 0.2 0.3474 0.9853 3122310 ChemDiv3_014468 CC1CCCC(NC(=O)Cn2c(cc3ccccc23)c4cccs4)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B15 compound treatment 0.261 0.0262 0.37 0.246 0.0121 0.2 0.4081 0.9587 3122311 ChemDiv3_014469 CCOc1ccc(CCNc2nnc3c4ccccc4n(CC)c3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B16 compound treatment 0.251 0.0162 0.23 0.212 -0.0219 -0.37 -0.0966 -0.2224 3122312 ChemDiv3_014470 CCc1ccc(NC(=O)N(Cc2ccco2)C3CCN(Cc4ccccc4)CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B17 compound treatment 0.254 0.0192 0.27 0.247 0.0131 0.22 0.3491 0.994 3038504 ChemDiv3_014471 CCc1ccc(NC(=O)CCCn2c(=O)c3cccn3c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B18 compound treatment 0.206 -0.0288 -0.41 0.207 -0.0269 -0.45 -0.6111 -0.999 3122313 ChemDiv3_014472 Cc1ccc(NC(=O)Cn2c(SCc3cccc(c3)C(F)(F)F)nc4cccnc24)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B19 compound treatment 0.221 -0.0138 -0.2 0.229 -0.00491 -0.08 -0.1982 -0.9244 3122314 ChemDiv3_014473 CC1CCC(CC1)NC(=O)C2CCCN2S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B20 compound treatment 0.208 -0.0268 -0.38 0.219 -0.0149 -0.25 -0.4484 -0.9785 3038507 ChemDiv3_014474 CCc1cccc(Nc2ncnc3n4CCCCCc4nc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B21 compound treatment 0.247 0.0122 0.17 0.237 0.00309 0.05 0.1597 0.8799 3122315 ChemDiv3_014475 Cc1ccc2c(CNCCc3ccco3)c(C(=O)O)n(Cc4ccccc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B22 compound treatment 0.274 0.0392 0.56 0.266 0.0321 0.54 0.7769 0.9998 3038510 ChemDiv3_014476 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)C4COc5ccccc5O4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B23 mock treatment 0.249 0.0142 0.2 0.232 -0.00191 -0.03 0.1206 0.5881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 B24 mock treatment 0.233 -0.00184 -0.03 0.237 0.00309 0.05 0.0181 0.3103 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C01 compound treatment 0.238 0.00316 0.05 0.214 -0.0199 -0.33 -0.2043 -0.6061 3122316 ChemDiv3_014477 CCNc1c(NC(=O)c2cccs2)c(=O)oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C02 compound treatment 0.25 0.0152 0.22 0.239 0.00509 0.09 0.2137 0.9172 3038514 ChemDiv3_014478 O=C(N1CCSC1=S)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C03 compound treatment 0.252 0.0172 0.25 0.233 -9.06E-4 -0.02 0.1628 0.662 3122317 ChemDiv3_014479 CCOC(=O)c1c(C(=O)OCC)c2-c3ccccc3Cn2c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C04 compound treatment 0.267 0.0322 0.46 0.227 -0.00691 -0.12 0.2433 0.5129 3122318 ChemDiv3_014480 CS(=O)(=O)c1ncc(Cl)c(n1)C(=O)Nc2sc3CCCc3c2C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C05 compound treatment 0.241 0.00616 0.09 0.251 0.0171 0.29 0.2651 0.8835 3038518 ChemDiv3_014481 COc1ccc(NC(=O)c2ccc3oc(=O)c(cc3c2)S(=O)(=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C06 compound treatment 0.044 -0.191 -2.73 0.238 0.00409 0.07 -1.8817 -0.6891 1673518 ChemDiv3_014482 COc1ccc(cc1)C(=O)COc2ccc3c(C)c(Cl)c(=O)oc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C07 compound treatment 0.234 -8.44E-4 -0.01 0.245 0.0111 0.19 0.1231 0.6599 3122507 ChemDiv3_014483 Brc1cc(NCc2ccccc2)c3C(=O)c4ccccc4-c5onc1c53 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C08 compound treatment 0.052 -0.183 -2.62 0.209 -0.0249 -0.42 -2.1449 -0.8098 3038557 ChemDiv3_014484 CC(N1CCn2c(C1)nc3cc(NC(=O)c4cccc(Br)c4)ccc23)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C09 compound treatment 0.255 0.0202 0.29 0.211 -0.0229 -0.38 -0.068 -0.1415 3122508 ChemDiv3_014485 CSc1ccc(CCNCc2c(C(=O)O)n(Cc3ccc(C=C)cc3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C10 compound treatment 0.278 0.0432 0.62 0.253 0.0191 0.32 0.6631 0.9534 3038560 ChemDiv3_014486 CC(C)c1ccc(cc1)N2CC(=O)C(=C2N)c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C11 compound treatment 0.241 0.00616 0.09 0.247 0.0131 0.22 0.2177 0.9194 3122509 ChemDiv3_014487 O=C(N1CCCCC1)c2cnn3c4CCCCCc4cnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C12 compound treatment 0.254 0.0192 0.27 0.283 0.0491 0.82 0.7764 0.8941 1294026 ChemDiv3_014488 COc1ccc2oc3cc(C)nc(c4ccccc4)c3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C13 compound treatment 0.225 -0.00984 -0.14 0.234 9.38E-5 0.0 -0.0984 -0.6992 3038564 ChemDiv3_014489 Cc1c(oc2ccc3OC4(CCCC4)C=Cc3c12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C14 compound treatment 0.223 -0.0118 -0.17 0.247 0.0131 0.22 0.0356 0.1283 3122510 ChemDiv3_014490 CC(Cc1ccccc1)Nc2nc3n(C)cnc3c(=N)n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C15 compound treatment 0.042 -0.193 -2.76 0.217 -0.0169 -0.28 -2.1511 -0.7758 3122511 ChemDiv3_014491 CCN1CCCC1CNc2nc3ccc(Cl)cc3n4cnnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C16 compound treatment 0.267 0.0322 0.46 0.242 0.00809 0.14 0.4213 0.8784 3122512 ChemDiv3_014492 Cc1ccc2oc(cc(=O)c2c1)C(=O)Nc3ccc(C)c(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C17 compound treatment 0.222 -0.0128 -0.18 0.231 -0.00291 -0.05 -0.1644 -0.8649 3038603 ChemDiv3_014493 Cc1n(CC(=O)Nc2ccc(C)cc2)c(C)c3c(=O)n(ncc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C18 compound treatment 0.256 0.0212 0.3 0.246 0.0121 0.2 0.3575 0.9811 3122513 ChemDiv3_014494 O=C([C@@H]1[C@@H]2C[C@@H]3OC(=O)[C@H]1[C@@H]3C2)N(Cc4ccccc4)Cc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C19 compound treatment 0.207 -0.0278 -0.4 0.235 0.00109 0.02 -0.2686 -0.6738 3038606 ChemDiv3_014495 Cc1nnc2sc(SCc3ccccc3)nn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C20 compound treatment 0.238 0.00316 0.05 0.215 -0.0189 -0.32 -0.1925 -0.6005 3122514 ChemDiv3_014496 CC(C)C(=O)/N=C/1\SC2CS(=O)(=O)CC2N1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C21 compound treatment 0.231 -0.00384 -0.05 0.222 -0.0119 -0.2 -0.1802 -0.8693 3038609 ChemDiv3_014497 Oc1nc2ccccc2cc1CN(C3CCCCC3)C(=O)c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C22 compound treatment 0.224 -0.0108 -0.16 0.218 -0.0159 -0.27 -0.2985 -0.9666 3122515 ChemDiv3_014498 CCc1cc(=O)oc2cc3occ(c3cc12)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C23 mock treatment 0.237 0.00216 0.03 0.224 -0.00991 -0.17 -0.0958 -0.5663 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 C24 mock treatment 0.219 -0.0158 -0.23 0.229 -0.00491 -0.08 -0.2185 -0.9061 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D01 compound treatment 0.242 0.00716 0.1 0.238 0.00409 0.07 0.121 0.9812 3038612 ChemDiv3_014499 COc1ccc(cc1)c2coc3cc4oc(=O)c(CC(=O)O)c(C)c4cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D02 compound treatment 0.214 -0.0208 -0.3 0.222 -0.0119 -0.2 -0.3521 -0.9811 3122516 ChemDiv3_014500 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D03 compound treatment 0.259 0.0242 0.35 0.261 0.0271 0.45 0.5659 0.9908 3122517 ChemDiv3_014501 COc1cccc(CN2COc3ccc4c5ccccc5c(=O)oc4c3C2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D04 compound treatment 0.289 0.0542 0.77 0.249 0.0151 0.25 0.7269 0.8919 3038616 ChemDiv3_014502 Cc1scc(CN2CCOCC2)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D05 compound treatment 0.305 0.0702 1.0 0.293 0.0591 0.99 1.4109 1.0 3038651 ChemDiv3_014503 COCc1cc(C)nc2sc3C(=O)NC4(CCCCC4)Nc3c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D06 compound treatment 0.264 0.0292 0.42 0.236 0.00209 0.04 0.3197 0.764 3038655 ChemDiv3_014504 OC(=O)C1=Cc2sc3CCCCc3c2CS1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D07 compound treatment 0.262 0.0272 0.39 0.246 0.0121 0.2 0.4182 0.9542 3122518 ChemDiv3_014505 CC(C)N(Cc1cccs1)Cc2cc(=O)oc3cc(C)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D08 compound treatment 0.255 0.0202 0.29 0.259 0.0251 0.42 0.5017 0.9829 3038657 ChemDiv3_014506 CSc1ncc(C(=O)O)c(n1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D09 compound treatment 0.293 0.0582 0.83 0.295 0.0611 1.03 1.3133 0.9946 3122519 ChemDiv3_014507 CN(C(=O)c1cccc(NC(=O)[C@H]2[C@H]3C[C@H]4OC(=O)[C@@H]2[C@H]4C3)c1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D10 compound treatment 0.264 0.0292 0.42 0.258 0.0241 0.4 0.5808 0.9999 3122520 ChemDiv3_014508 CC1CCCC(C1C)N(Cc2ccco2)C(=O)NCc3noc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D11 compound treatment 0.262 0.0272 0.39 0.27 0.0361 0.61 0.703 0.9769 3038663 ChemDiv3_014509 O=c1[nH]c(nc2Oc3ccccc3Cc21)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D12 compound treatment 0.282 0.0472 0.67 0.238 0.00409 0.07 0.5255 0.7751 3122521 ChemDiv3_014510 Nc1c(nnn1c2cccc(c2)C(F)(F)F)c3nc(no3)c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D13 compound treatment 0.271 0.0362 0.52 0.287 0.0531 0.89 0.9958 0.9665 3038665 ChemDiv3_014511 CCOc1ccccc1NC(=O)CSc2nc3nccnc3c(=O)n2Cc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D14 compound treatment 0.255 0.0202 0.29 0.246 0.0121 0.2 0.3474 0.9853 3122522 ChemDiv3_014512 CC1Cn2cc(C(=O)Nc3cccc(F)c3)c(=O)c4c(Cl)ccc(O1)c24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D15 compound treatment 0.268 0.0332 0.47 0.251 0.0171 0.29 0.5382 0.971 3122523 ChemDiv3_014513 CC1CN(CCCNc2nnc3c4ccccc4n(C)c3n2)CCN1c5cccc(C)c5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D16 compound treatment 0.285 0.0502 0.72 0.267 0.0331 0.56 0.9001 0.992 3038700 ChemDiv3_014514 CCN1CCC(CC1)N(Cc2ccco2)C(=O)Nc3cc(C)cc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D17 compound treatment 0.289 0.0542 0.77 0.298 0.0641 1.08 1.3084 0.987 3122524 ChemDiv3_014515 CC(C)NC(=O)CCCn1c(=O)c2cccn2c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D18 compound treatment 0.259 0.0242 0.35 0.185 -0.0489 -0.82 -0.3361 -0.3774 3122525 ChemDiv3_014516 CC(NC(=O)c1ccc(cc1)n2c(C)cc3CCCCc32)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D19 compound treatment 0.287 0.0522 0.75 0.289 0.0551 0.92 1.1814 0.9943 3038706 ChemDiv3_014517 Cc1ccc(NC(=O)CCNS(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D20 compound treatment 0.168 -0.0668 -0.96 0.15 -0.0839 -1.41 -1.6719 -0.9822 3122526 ChemDiv3_014518 Cc1ccc(CNc2ncnc3n4CCCCCc4nc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D21 compound treatment 0.244 0.00916 0.13 0.219 -0.0149 -0.25 -0.0843 -0.2985 3038709 ChemDiv3_014519 CN(Cc1ccccc1)C(=O)Cn2c(=O)c3cccn3c4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D22 compound treatment 0.285 0.0502 0.72 0.245 0.0111 0.19 0.639 0.8621 3122527 ChemDiv3_014520 Cc1cc(Nc2cccc(Cl)c2)nc3ccc(NC(=O)c4ccccn4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D23 mock treatment 0.225 -0.00984 -0.14 0.262 0.0281 0.47 0.2339 0.4752 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 D24 mock treatment 0.211 -0.0238 -0.34 0.238 0.00409 0.07 -0.1926 -0.5535 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E01 compound treatment 0.235 1.56E-4 0.0 0.236 0.00209 0.04 0.0264 0.7506 3038712 ChemDiv3_014521 CCNc1c(NS(=O)(=O)CC)c(=O)oc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E02 compound treatment 0.216 -0.0188 -0.27 0.234 9.38E-5 0.0 -0.1895 -0.703 3122528 ChemDiv3_014522 CC1(C)N=C(Nc2ccccc2)SC1=N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E03 compound treatment 0.274 0.0392 0.56 0.233 -9.06E-4 -0.02 0.3853 0.6876 3122529 ChemDiv3_014523 CCOC(=O)C1=C(Cn2ccnc2)NC(=O)NC1c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E04 compound treatment 0.219 -0.0158 -0.23 0.131 -0.103 -1.73 -1.3815 -0.7931 3122530 ChemDiv3_014524 CN(Cc1ccccc1)S(=O)(=O)c2ccc(NC(=O)c3nc(ncc3Cl)S(=O)(=O)C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E05 compound treatment 0.278 0.0432 0.62 0.25 0.0161 0.27 0.6275 0.9313 3122531 ChemDiv3_014525 Cc1c(C2CCN(CC2)S(=O)(=O)c3ccc(C)c(C)c3)c4ccccc4n1CC(=O)N5CCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E06 compound treatment 0.271 0.0362 0.52 0.244 0.0101 0.17 0.4855 0.8921 3037862 ChemDiv3_014526 COc1ccc(cc1)C2CC(=NCCN2Cc3cccc(C)c3)c4c(O)c5ccccc5oc4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E07 compound treatment 0.257 0.0222 0.32 0.26 0.0261 0.44 0.5338 0.9874 3122532 ChemDiv3_014527 CC1CCN(CC1)c2cc(N(C)C)c3noc4-c5ccccc5C(=O)c2c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E08 compound treatment 0.276 0.0412 0.59 0.258 0.0241 0.4 0.7022 0.9832 3037865 ChemDiv3_014528 CC(=O)N(Cc1nnc2c3ccccc3c(C)nn12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E09 compound treatment 0.264 0.0292 0.42 0.25 0.0161 0.27 0.4859 0.9779 3122533 ChemDiv3_014529 Cc1ccc(cc1C)C(=O)c2cnc3cc4OCOc4cc3c2S(=O)(=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E10 compound treatment 0.316 0.0812 1.16 0.308 0.0741 1.24 1.7002 0.9994 3122715 ChemDiv3_014530 CC(N1CC(=O)C(=C1N)c2nc3ccccc3[nH]2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E11 compound treatment 0.24 0.00516 0.07 0.279 0.0451 0.76 0.5873 0.7724 3037870 ChemDiv3_014531 C(NCc1c[nH]nc1c2ccccc2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E12 compound treatment 0.225 -0.00984 -0.14 0.223 -0.0109 -0.18 -0.229 -0.9916 3122716 ChemDiv3_014532 CN(C)Cc1c(C)n(Cc2ccccc2)c3C(=O)c4ccc(Br)cc4-c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E13 compound treatment 0.231 -0.00384 -0.05 0.245 0.0111 0.19 0.0928 0.4779 3037873 ChemDiv3_014533 OC(=O)C1CCCN(C1)c2ncnc3c2sc4cccc(F)c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E14 compound treatment 0.326 0.0912 1.3 0.293 0.0591 0.99 1.6233 0.9909 1603379 ChemDiv3_014534 Cc1ccc(cc1)C(N(Cc2ccco2)C(=O)Cn3nnc4ccccc34)C(=O)NCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E15 compound treatment 0.27 0.0352 0.5 0.261 0.0271 0.45 0.6771 0.9987 3122717 ChemDiv3_014535 O=C(NCc1ccco1)c2ccc(Cn3c(SCc4ccccc4)nc5ccncc35)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E16 compound treatment 0.266 0.0312 0.45 0.261 0.0271 0.45 0.6367 0.9999 3037909 ChemDiv3_014536 OC(=O)CNC(=O)C(O)(c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E17 compound treatment 0.282 0.0472 0.67 0.293 0.0591 0.99 1.1783 0.9823 3122718 ChemDiv3_014537 COc1ccc2C3CC(C)(NC(=O)C3S(=O)(=O)c4ccccc4)Oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E18 compound treatment 0.251 0.0162 0.23 0.282 0.0481 0.81 0.7342 0.8744 3122719 ChemDiv3_014538 O=C([C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)N4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E19 compound treatment 0.266 0.0312 0.45 0.235 0.00109 0.02 0.3281 0.7356 3037913 ChemDiv3_014539 CC(C)C(=O)Oc1cc(c2ccccc2)c3oc(=O)sc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E20 compound treatment 0.267 0.0322 0.46 0.282 0.0481 0.81 0.896 0.9644 3122720 ChemDiv3_014540 COc1ccc(cc1)N/2C3CS(=O)(=O)CC3S\C2=N/C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E21 compound treatment 0.237 0.00216 0.03 0.26 0.0261 0.44 0.3315 0.755 3037915 ChemDiv3_014541 CC(=O)Nc1ccc2n3CCN(Cc3nc2c1)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E22 compound treatment 0.244 0.00916 0.13 0.243 0.00909 0.15 0.2005 0.9971 1430336 ChemDiv3_014542 CCc1c(C)c2cc3c(C)coc3cc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E23 mock treatment 0.259 0.0242 0.35 0.229 -0.00491 -0.08 0.1861 0.5239 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 E24 mock treatment 0.226 -0.00884 -0.13 0.235 0.00109 0.02 -0.0765 -0.5982 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F01 compound treatment 0.247 0.0122 0.17 0.239 0.00509 0.09 0.1834 0.9466 3037919 ChemDiv3_014543 Cc1c(CC(=O)O)c(=O)oc2cc3oc4CCCCc4c3cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F02 compound treatment 0.233 -0.00184 -0.03 0.227 -0.00691 -0.12 -0.1006 -0.8464 3037970 ChemDiv3_014544 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F03 compound treatment 0.232 -0.00284 -0.04 0.268 0.0341 0.57 0.3759 0.6552 3122721 ChemDiv3_014545 COC(=O)Cc1c(C)c2ccc3OCN(Cc4cccc(OC)c4)Cc3c2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F04 compound treatment 0.253 0.0182 0.26 0.269 0.0351 0.59 0.6001 0.9323 3037976 ChemDiv3_014546 Cc1scc(CN2CCC3(CC2)OCCO3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F05 compound treatment 0.303 0.0682 0.97 0.299 0.0651 1.09 1.4619 0.9984 3122722 ChemDiv3_014547 Cc1cc(NCC=C)n2cnnc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F06 compound treatment 0.286 0.0512 0.73 0.307 0.0731 1.23 1.3849 0.9695 3037979 ChemDiv3_014548 Cc1sc2C=C(SCc2c1C)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F07 compound treatment 0.276 0.0412 0.59 0.319 0.0851 1.43 1.4262 0.9232 3122723 ChemDiv3_014549 COc1ccc2oc(=O)cc(CN3CCN(CC3)c4ncccn4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F08 compound treatment 0.296 0.0612 0.87 0.322 0.0881 1.48 1.6641 0.9686 3037982 ChemDiv3_014550 CSc1nc(nc2Oc3c(C)ncc(CO)c3Cc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F09 compound treatment 0.313 0.0782 1.12 0.324 0.0901 1.51 1.8597 0.989 3122724 ChemDiv3_014551 O=C(Nc1nnc(s1)N2CCCCC2)NC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F10 compound treatment 0.289 0.0542 0.77 0.309 0.0751 1.26 1.439 0.9727 3122725 ChemDiv3_014552 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N(CC=C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F11 compound treatment 0.287 0.0522 0.75 0.293 0.0591 0.99 1.2289 0.9901 3037986 ChemDiv3_014553 Cn1nc(C(=O)NCc2ccco2)c3CSc4ccccc4-c31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F12 compound treatment 0.304 0.0692 0.99 0.27 0.0361 0.61 1.1278 0.9723 3122726 ChemDiv3_014554 Cc1ccc(Cl)cc1n2nnc(c2N)c3nc(no3)c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F13 compound treatment 0.307 0.0722 1.03 0.282 0.0481 0.81 1.3006 0.9926 3038036 ChemDiv3_014555 CCn1c2ccccc2c3nnc(nc13)N4CCC(CC4)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F14 compound treatment 0.268 0.0332 0.47 0.303 0.0691 1.16 1.1554 0.9222 3122727 ChemDiv3_014556 O=C(NC1(CC2CC3CC(C2)C1)C3)N4CCC(CN5CCCCC5)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F15 compound treatment 0.281 0.0462 0.66 0.301 0.0671 1.13 1.2631 0.9676 3038040 ChemDiv3_014557 FC(F)(F)c1cccc(Cn2ccn(c3cccc(Cl)c3)c(=O)c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F16 compound treatment 0.25 0.0152 0.22 0.268 0.0341 0.57 0.5579 0.9118 3122728 ChemDiv3_014558 CCN1CCC(CC1)N(Cc2ccco2)C(=O)Nc3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F17 compound treatment 0.31 0.0752 1.08 0.318 0.0841 1.41 1.7582 0.991 3122729 ChemDiv3_014559 CC(NC(=O)CCCn1c(=O)c2cccn2c3ccccc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F18 compound treatment 0.309 0.0742 1.06 0.285 0.0511 0.86 1.3564 0.9944 3038047 ChemDiv3_014560 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F19 compound treatment 0.365 0.13 1.86 0.301 0.0671 1.13 2.1127 0.971 3122730 ChemDiv3_014561 O=C(NCc1ccccc1)C2CCCN(C2)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F20 compound treatment 0.323 0.0882 1.26 0.287 0.0531 0.89 1.5218 0.9856 3038050 ChemDiv3_014562 C(Cc1ccsc1)Nc2ncnc3n4CCCCCc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F21 compound treatment 0.31 0.0752 1.08 0.275 0.0411 0.69 1.2479 0.977 3122731 ChemDiv3_014563 CNC(=O)Cn1c(=O)c2cccn2c3cccnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F22 compound treatment 0.274 0.0392 0.56 0.235 0.00109 0.02 0.409 0.7299 3038054 ChemDiv3_014564 CCc1nnc(NC(=O)c2nc(c3ccc(Cl)cc3)n4CCCCCc24)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F23 mock treatment 0.253 0.0182 0.26 0.237 0.00309 0.05 0.2204 0.832 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 F24 mock treatment 0.243 0.00816 0.12 0.225 -0.00891 -0.15 -0.0232 -0.1224 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G01 compound treatment 0.239 0.00416 0.06 0.224 -0.00991 -0.17 -0.0755 -0.4278 3122732 ChemDiv3_014565 CCn1c(=O)c(O)nc2c(=O)oc3ccccc3c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G02 compound treatment 0.283 0.0482 0.69 0.227 -0.00691 -0.12 0.4051 0.58 3122733 ChemDiv3_014566 Clc1ccc(OCc2nc3c4cnn(c5ccc(Cl)cc5)c4ncn3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G03 compound treatment 0.26 0.0252 0.36 0.286 0.0521 0.87 0.8727 0.923 3040359 ChemDiv3_014567 CCC(C)NS(=O)(=O)c1ccc2NC(=O)Cc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G04 compound treatment 0.302 0.0672 0.96 0.311 0.0771 1.29 1.5942 0.9892 3040360 ChemDiv3_014568 CSc1ncc(Cl)c(n1)C(=O)Oc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G05 compound treatment 0.299 0.0642 0.92 0.274 0.0401 0.67 1.1247 0.9884 3040361 ChemDiv3_014569 C1CN2C(N2C1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G06 compound treatment 0.283 0.0482 0.69 0.287 0.0531 0.89 1.1172 0.9919 3040362 ChemDiv3_014570 Clc1ccc(CN(Cc2ccco2)C(=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G07 compound treatment 0.316 0.0812 1.16 0.316 0.0821 1.38 1.7951 0.9964 3040363 ChemDiv3_014571 COc1ccc(cc1OC)C2=NOC(C2)C(=O)N3CC4(C)CC3CC(C)(C)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G08 compound treatment 0.33 0.0952 1.36 0.316 0.0821 1.38 1.9367 1.0 3040364 ChemDiv3_014572 Cc1nn2c(CN(C(=O)c3ccccc3)c4ccccc4)nnc2c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G09 compound treatment 0.265 0.0302 0.43 0.28 0.0461 0.77 0.8521 0.9619 3040365 ChemDiv3_014573 CCc1ccc(cc1)S(=O)(=O)c2c(cnc3cc4OCCOc4cc23)C(=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G10 compound treatment 0.294 0.0592 0.85 0.311 0.0771 1.29 1.5133 0.9788 3122734 ChemDiv3_014574 NC1=C(C(=O)CN1CC=C)c2nc3ccccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G11 compound treatment 0.301 0.0662 0.95 0.259 0.0251 0.42 0.9669 0.9335 3122735 ChemDiv3_014575 O=C(NCc1ccccc1)c2cc(c(s2)N3CCOCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G12 compound treatment 0.249 0.0142 0.2 0.262 0.0281 0.47 0.4766 0.9287 3040366 ChemDiv3_014576 Nc1c2CCCCCc2nc3ccn(c4ccccc4)c(=O)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G13 compound treatment 0.294 0.0592 0.85 0.274 0.0401 0.67 1.0742 0.9936 3122736 ChemDiv3_014577 CCC(C(=O)O)n1nc(C)c2sc3ccccc3c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G14 compound treatment 0.287 0.0522 0.75 0.286 0.0521 0.87 1.1458 0.9969 1735091 ChemDiv3_014578 CCC(=O)c1c(C)nc2n(Cc3ccccc3)c4ccccc4n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G15 compound treatment 0.294 0.0592 0.85 0.287 0.0531 0.89 1.2284 0.9997 3122737 ChemDiv3_014579 Cc1c(CNC2CCCC2)c(C(=O)O)c(C)n1Cc3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G16 compound treatment 0.253 0.0182 0.26 0.232 -0.00191 -0.03 0.161 0.6153 3122738 ChemDiv3_014580 CCOc1ccc(cc1OCC)c2nonc2NC(=O)c3oc4cc(C)c(Cl)cc4c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G17 compound treatment 0.297 0.0622 0.89 0.269 0.0351 0.59 1.0452 0.98 3040367 ChemDiv3_014581 CC(C)c1ccc(cc1)S(=O)(=O)C2C3CC(C)(Oc4ccccc34)N(C)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G18 compound treatment 0.314 0.0792 1.13 0.291 0.0571 0.96 1.4782 0.9966 3122739 ChemDiv3_014582 CN(C(=O)[C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G19 compound treatment 0.278 0.0432 0.62 0.22 -0.0139 -0.23 0.2715 0.4113 3040368 ChemDiv3_014583 Cc1ccc2occ(CC(=O)Nc3nc4ccc(cc4s3)S(=O)(=O)C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G20 compound treatment 0.237 0.00216 0.03 0.245 0.0111 0.19 0.1535 0.8132 3122740 ChemDiv3_014584 CCc1cc(=O)oc2cc(C)c3c(coc3c12)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G21 compound treatment 0.238 0.00316 0.05 0.219 -0.0149 -0.25 -0.145 -0.5703 3040369 ChemDiv3_014585 CN(Cc1nc2ccccc2n1C)C(=O)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G22 compound treatment 0.3 0.0652 0.93 0.215 -0.0189 -0.32 0.4346 0.4415 3122741 ChemDiv3_014586 CCc1c(C)c2cc3c(coc3cc2oc1=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G23 mock treatment 0.233 -0.00184 -0.03 0.224 -0.00991 -0.17 -0.1362 -0.8091 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 G24 mock treatment 0.214 -0.0208 -0.3 0.224 -0.00991 -0.17 -0.3284 -0.962 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H01 compound treatment 0.245 0.0102 0.15 0.262 0.0281 0.47 0.4361 0.884 1263075 ChemDiv3_014587 O=c1oc2cc3occ(c4ccccc4)c3cc2c5CCCc51 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H02 compound treatment 0.256 0.0212 0.3 0.265 0.0311 0.52 0.583 0.9664 3040370 ChemDiv3_014588 COc1ccc(CCNC(=O)c2ccc(Cl)cc2NC(=O)C3=C(C)OCCS3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H03 compound treatment 0.259 0.0242 0.35 0.27 0.0361 0.61 0.6727 0.9646 3122916 ChemDiv3_014589 CCCCc1cc(=O)oc2c3CN(Cc4ccc(OC)c(OC)c4)COc3c(Cl)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H04 compound treatment 0.268 0.0332 0.47 0.301 0.0671 1.13 1.1316 0.9261 3040371 ChemDiv3_014590 CCN1CCN(Cc2csc(C)c2C)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H05 compound treatment 0.343 0.108 1.55 0.289 0.0551 0.92 1.7478 0.9697 3122917 ChemDiv3_014591 FC(F)(F)c1cccc(c1)n2cnnn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H06 compound treatment 0.258 0.0232 0.33 0.317 0.0831 1.39 1.2204 0.8514 3040372 ChemDiv3_014592 Cc1scc(CSCC(=O)O)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H07 compound treatment 0.299 0.0642 0.92 0.255 0.0211 0.35 0.8992 0.9142 3122918 ChemDiv3_014593 CCOc1ccc(cc1)N(C)Cc2cc(=O)oc3ccc(OC)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H08 compound treatment 0.297 0.0622 0.89 0.292 0.0581 0.98 1.3181 0.9989 3122919 ChemDiv3_014594 O=c1n(Cc2ccccc2)c(=O)c3oc4ccccc4c3n1Cc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H09 compound treatment 0.291 0.0562 0.8 0.29 0.0561 0.94 1.2337 0.9969 3040373 ChemDiv3_014595 CCc1ccccc1NC(=O)NCc2c(sc3CCCCc23)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H10 compound treatment 0.28 0.0452 0.65 0.28 0.0461 0.77 1.0038 0.996 3122920 ChemDiv3_014596 CSc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H11 compound treatment 0.29 0.0552 0.79 0.253 0.0191 0.32 0.7845 0.9212 3040374 ChemDiv3_014597 Cn1nc(C(=O)N(Cc2ccco2)C3CCCCC3)c4CSc5ccccc5-c41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H12 compound treatment 0.321 0.0862 1.23 0.306 0.0721 1.21 1.727 1.0 3122921 ChemDiv3_014598 Cn1c(=O)c2sccc2n3c(CCCC(=O)Nc4ccccc4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H13 compound treatment 0.238 0.00316 0.05 0.275 0.0411 0.69 0.5196 0.7518 3122922 ChemDiv3_014599 CCn1c2ccccc2c3nnc(nc13)N4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H14 compound treatment 0.296 0.0612 0.87 0.299 0.0651 1.09 1.3911 0.9939 3040375 ChemDiv3_014600 CCCN(CCC)C(=O)CSc1nnc(c2cc3sccc3n2C)n1c4c(C)cc(C)cc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H15 compound treatment 0.3 0.0652 0.93 0.278 0.0441 0.74 1.1823 0.9935 3122923 ChemDiv3_014601 O=C(NCCOC1(CC2CC3CC(C2)C1)C3)c4nc(no4)c5cccnc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H16 compound treatment 0.317 0.0822 1.18 0.289 0.0551 0.92 1.4848 0.993 3122924 ChemDiv3_014602 CCN1CCC(CC1)N(Cc2cccc(OC)c2)C(=O)NC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H17 compound treatment 0.315 0.0802 1.15 0.327 0.0931 1.56 1.9156 0.9884 3040376 ChemDiv3_014603 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H18 compound treatment 0.315 0.0802 1.15 0.313 0.0791 1.33 1.7494 0.9973 3122925 ChemDiv3_014604 CCOC(=O)c1cc(C)n(c1C)c2ccc(cc2)C(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H19 compound treatment 0.25 0.0152 0.22 0.278 0.0441 0.74 0.6766 0.8774 3040377 ChemDiv3_014605 CCC(Sc1nncn2c3ccsc3cc12)C(=O)Nc4ccccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H20 compound treatment 0.098 -0.137 -1.96 0.104 -0.13 -2.18 -2.9258 -0.9986 3122926 ChemDiv3_014606 CC(Sc1ncc(c(N)n1)S(=O)(=O)c2ccccc2)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H21 compound treatment 0.29 0.0552 0.79 0.28 0.0461 0.77 1.1049 1.0 3122927 ChemDiv3_014607 CN(Cc1ccccc1)C(=O)CCCn2c(=O)c3cccn3c4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H22 compound treatment 0.27 0.0352 0.5 0.23 -0.00391 -0.07 0.3092 0.6098 3040378 ChemDiv3_014608 Cc1sc2C=C(SCc2c1C)C(=O)Nc3cccc(C)c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H23 mock treatment 0.245 0.0102 0.15 0.222 -0.0119 -0.2 -0.0386 -0.1562 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 H24 mock treatment 0.225 -0.00984 -0.14 0.23 -0.00391 -0.07 -0.1459 -0.9395 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I01 compound treatment 0.237 0.00216 0.03 0.238 0.00409 0.07 0.0704 0.9347 3122928 ChemDiv3_014609 COC(=O)c1nnn(c1C(=O)OC)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I02 compound treatment 0.243 0.00816 0.12 0.241 0.00709 0.12 0.1667 0.9999 3040379 ChemDiv3_014610 Clc1ccc(cc1)n2ncc3c4nc(nn4cnc23)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I03 compound treatment 0.253 0.0182 0.26 0.269 0.0351 0.59 0.6001 0.9323 3122929 ChemDiv3_014611 O=C1Cc2cc(ccc2N1)S(=O)(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I04 compound treatment 0.276 0.0412 0.59 0.293 0.0591 0.99 1.1176 0.969 3122930 ChemDiv3_014612 CCOC(=O)Cn1c2SC3C4CCC(C4)C3C(c2sc1=O)c5ccc(Cl)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I05 compound treatment 0.308 0.0732 1.05 0.303 0.0691 1.16 1.5599 0.9987 3040380 ChemDiv3_014613 CCOc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccc(F)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I06 compound treatment 0.297 0.0622 0.89 0.272 0.0381 0.64 1.0808 0.9869 3122931 ChemDiv3_014614 Cc1ccc(CN(Cc2ccco2)C(=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I07 compound treatment 0.283 0.0482 0.69 0.307 0.0731 1.23 1.3545 0.9628 3122932 ChemDiv3_014615 COc1cccc2Cc3c(SCC(=O)N(C)c4ccccc4)nc(nc3Oc12)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I08 compound treatment 0.291 0.0562 0.8 0.316 0.0821 1.38 1.5423 0.967 3040381 ChemDiv3_014616 CCCCN1C(c2c(n[nH]c2C1=O)c3ccccc3O)c4cccc(O)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I09 compound treatment 0.241 0.00616 0.09 0.275 0.0411 0.69 0.55 0.791 3122933 ChemDiv3_014617 CCOc1ccc(cc1)S(=O)(=O)c2c(cnc3ccc(F)cc23)C(=O)c4ccc(C)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I10 compound treatment 0.243 0.00816 0.12 0.303 0.0691 1.16 0.9025 0.7743 3040382 ChemDiv3_014618 NC1=C(C(=O)CN1C2CCCCCC2)c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I11 compound treatment 0.302 0.0672 0.96 0.273 0.0391 0.66 1.1432 0.9827 3122934 ChemDiv3_014619 OC(=O)c1cnn(c1n2cccc2CNCc3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I12 compound treatment 0.28 0.0452 0.65 0.277 0.0431 0.72 0.9682 0.9984 3040383 ChemDiv3_014620 COc1ccc2n3CCN=C(N(C)C)c3c(C#N)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I13 compound treatment 0.277 0.0422 0.6 0.281 0.0471 0.79 0.9853 0.9911 3122935 ChemDiv3_014621 Brc1ccc(cc1)S(=O)Cc2ccc(o2)C(=O)NC3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I14 compound treatment 0.304 0.0692 0.99 0.285 0.0511 0.86 1.3058 0.9975 1505736 ChemDiv3_014622 CCN(CC)CCn1c2nc(c(C(=O)CC)n2c3ccccc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I15 compound treatment 0.295 0.0602 0.86 0.276 0.0421 0.71 1.108 0.9952 3122936 ChemDiv3_014623 Cc1c(CNCCc2c[nH]c3ccccc23)c(C(=O)O)c(C)n1Cc4ccc(F)cc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I16 compound treatment 0.237 0.00216 0.03 0.221 -0.0129 -0.22 -0.1314 -0.6004 3122937 ChemDiv3_014624 CCCCC1CCC(CC1)C(=O)Nc2nonc2c3ccc(OCC)c(OCC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I17 compound treatment 0.158 -0.0768 -1.1 0.218 -0.0159 -0.27 -0.966 -0.854 3040384 ChemDiv3_014625 CCc1ccccc1N2CC(CC2=O)c3nc4ccccc4n3CCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I18 compound treatment 0.28 0.0452 0.65 0.293 0.0591 0.99 1.1581 0.9784 3122938 ChemDiv3_014626 O=C([C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I19 compound treatment 0.286 0.0512 0.73 0.288 0.0541 0.91 1.1594 0.9943 3040385 ChemDiv3_014627 CC(C)COC(=O)c1sc(NC(=O)Cc2coc3cc(C)cc(C)c23)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I20 compound treatment 0.264 0.0292 0.42 0.235 0.00109 0.02 0.3079 0.7375 3122939 ChemDiv3_014628 Cc1ccc(cc1)S(=O)(=O)N(CC=C)c2nccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I21 compound treatment 0.206 -0.0288 -0.41 0.192 -0.0419 -0.7 -0.7891 -0.9677 3122940 ChemDiv3_014629 COc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)Nc3nc4CCCCc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I22 compound treatment 0.185 -0.0498 -0.71 0.202 -0.0319 -0.54 -0.8828 -0.9901 3040386 ChemDiv3_014630 Cc1c(CCC(=O)O)c(=O)oc2cc3occ(c3cc12)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I23 mock treatment 0.221 -0.0138 -0.2 0.226 -0.00791 -0.13 -0.2339 -0.981 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 I24 mock treatment 0.199 -0.0358 -0.51 0.221 -0.0129 -0.22 -0.5157 -0.9266 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J01 compound treatment 0.237 0.00216 0.03 0.249 0.0151 0.25 0.2009 0.7874 3122941 ChemDiv3_014631 Cc1c2occ(c2cc3c4CCCCc4c(=O)oc13)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J02 compound treatment 0.224 -0.0108 -0.16 0.222 -0.0119 -0.2 -0.251 -0.9922 3122942 ChemDiv3_014632 CC(C)Oc1ccc(CNC(=O)c2ccc(Cl)cc2NC(=O)C3=C(C)OCCS3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J03 compound treatment 0.262 0.0272 0.39 0.278 0.0441 0.74 0.798 0.9547 3040387 ChemDiv3_014633 CCc1cc(=O)oc2c(C)c3OCN(Cc4ccccc4)Cc3cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J04 compound treatment 0.274 0.0392 0.56 0.269 0.0351 0.59 0.8125 0.9997 3040388 ChemDiv3_014634 Cc1cc(CN2CCc3ccccc3C2)cs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J05 compound treatment 0.295 0.0602 0.86 0.255 0.0211 0.35 0.8588 0.923 3122943 ChemDiv3_014635 Cc1cccc(c1)n2nnc(n2)c3ccc(cc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J06 compound treatment 0.287 0.0522 0.75 0.302 0.0681 1.14 1.3357 0.9786 3040389 ChemDiv3_014636 CC(C)NC(=O)CSCc1csc2CCCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J07 compound treatment 0.251 0.0162 0.23 0.268 0.0341 0.57 0.568 0.9204 3123121 ChemDiv3_014637 COc1ccc2oc(=O)cc(CN(C)c3c(C)cc(C)cc3C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J08 compound treatment 0.272 0.0372 0.53 0.276 0.0421 0.71 0.8754 0.9902 3123122 ChemDiv3_014638 CCc1ccc(NC(=O)Cn2c(=O)n(C(C)C)c(=O)c3oc4ccccc4c23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J09 compound treatment 0.262 0.0272 0.39 0.276 0.0421 0.71 0.7742 0.9603 3040390 ChemDiv3_014639 CCc1ccc(CN(Cc2c[nH]nc2c3ccc(OC)cc3)C(=O)Nc4ccc5OCCOc5c4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J10 compound treatment 0.282 0.0472 0.67 0.287 0.0531 0.89 1.1071 0.9906 3123123 ChemDiv3_014640 CCc1ccccc1NC(=O)CCNS(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J11 compound treatment 0.271 0.0362 0.52 0.298 0.0641 1.08 1.1264 0.9437 3040391 ChemDiv3_014641 CC(=O)Nc1nn2c(nnc2s1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J12 compound treatment 0.297 0.0622 0.89 0.301 0.0671 1.13 1.4249 0.9932 3123124 ChemDiv3_014642 CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J13 compound treatment 0.314 0.0792 1.13 0.321 0.0871 1.46 1.8342 0.992 3123125 ChemDiv3_014643 CCN(CCCNc1nnc2c3ccccc3n(CC)c2n1)c4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J14 compound treatment 0.313 0.0782 1.12 0.308 0.0741 1.24 1.6698 0.9986 3040443 ChemDiv3_014644 Cc1ccc(C)c(c1)n2c(SCc3ccc(C#N)cc3)nnc2c4cc5sccc5n4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J15 compound treatment 0.319 0.0842 1.2 0.311 0.0771 1.29 1.7661 0.9993 3040444 ChemDiv3_014645 CC1CCCCN1S(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J16 compound treatment 0.285 0.0502 0.72 0.247 0.0131 0.22 0.6627 0.8832 3040445 ChemDiv3_014646 CCN1CCC(CC1)N(Cc2ccc(F)cc2)C(=O)NC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J17 compound treatment 0.26 0.0252 0.36 0.296 0.0621 1.04 0.9914 0.8992 3040446 ChemDiv3_014647 CN(C1CCCCC1)S(=O)(=O)c2cc3OCC(=O)Nc3cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J18 compound treatment 0.307 0.0722 1.03 0.327 0.0931 1.56 1.8346 0.9797 3040447 ChemDiv3_014648 CCOc1ccc(CCNc2ncnc3n4CCCCCc4nc23)cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J19 compound treatment 0.296 0.0612 0.87 0.283 0.0491 0.82 1.2012 0.9996 3040448 ChemDiv3_014649 CCCNC(=O)C1CCCN(C1)S(=O)(=O)N2CCC3(CC2)OCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J20 compound treatment 0.309 0.0742 1.06 0.274 0.0401 0.67 1.2259 0.9759 3123126 ChemDiv3_014650 CCc1ccc(NC(=O)CSc2ncc(c(N)n2)S(=O)(=O)c3ccc(cc3)C(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J21 compound treatment 0.29 0.0552 0.79 0.265 0.0311 0.52 0.9269 0.9799 3123127 ChemDiv3_014651 Fc1ccccc1NC(=O)CCCn2c(=O)c3cccn3c4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J22 compound treatment 0.143 -0.0918 -1.31 0.153 -0.0809 -1.36 -1.8891 -0.9999 3040449 ChemDiv3_014652 COc1ccc(CNC(=O)C2=Cc3sc(C)c(C)c3CS2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J23 mock treatment 0.261 0.0262 0.37 0.252 0.0181 0.3 0.4793 0.9946 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 J24 mock treatment 0.237 0.00216 0.03 0.241 0.00709 0.12 0.106 0.8618 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K01 compound treatment 0.227 -0.00784 -0.11 0.258 0.0241 0.4 0.2066 0.4923 3123128 ChemDiv3_014653 CC(C)S(=O)(=O)C1=NSC2=NC(=O)/C(=C\c3ccco3)/C(=N)N12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K02 compound treatment 0.267 0.0322 0.46 0.266 0.0321 0.54 0.7061 0.9969 3040450 ChemDiv3_014654 CCOC(=O)Nc1noc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K03 compound treatment 0.272 0.0372 0.53 0.301 0.0671 1.13 1.1721 0.9413 3123129 ChemDiv3_014655 CCOC(=O)C1=C(CNCc2ccccc2)NC(=O)NC1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K04 compound treatment 0.301 0.0662 0.95 0.277 0.0431 0.72 1.1806 0.9912 1506560 ChemDiv3_014656 Cc1ccc(NC(=O)CSc2nc3c(N)ncnc3[nH]2)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K05 compound treatment 0.302 0.0672 0.96 0.249 0.0151 0.25 0.8584 0.864 3123130 ChemDiv3_014657 Cc1ccc(s1)C(O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K06 compound treatment 0.288 0.0532 0.76 0.3 0.0661 1.11 1.322 0.983 3123131 ChemDiv3_014658 Cc1c(oc2c(C)c(C)ccc12)C(=O)N(Cc3ccco3)Cc4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K07 compound treatment 0.292 0.0572 0.82 0.25 0.0161 0.27 0.7691 0.8932 3040451 ChemDiv3_014659 CCOC(=O)c1oc2ccc3nc(sc3c2c1C)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K08 compound treatment 0.313 0.0782 1.12 0.288 0.0541 0.91 1.4325 0.9947 1055095 ChemDiv3_014660 CS(=O)(=O)n1cnc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K09 compound treatment 0.27 0.0352 0.5 0.29 0.0561 0.94 1.0213 0.9569 3123132 ChemDiv3_014661 CCc1cc2n(Cc3ccc(Br)cc3F)c(cc2s1)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K10 compound treatment 0.258 0.0232 0.33 0.306 0.0721 1.21 1.0898 0.8687 3040452 ChemDiv3_014662 CC(C)CNS(=O)(=O)C1CCS(=O)(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K11 compound treatment 0.235 1.56E-4 0.0 0.298 0.0641 1.08 0.7623 0.7086 3123133 ChemDiv3_014663 COc1ccccc1N2C(=O)C3CSC(N3C2=O)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K12 compound treatment 0.165 -0.0698 -1.0 0.19 -0.0439 -0.74 -1.2275 -0.9888 1145036 ChemDiv3_014664 OC(=O)c1ccn2c(C(=O)c3ccccc3)c(cc2c1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K13 compound treatment 0.282 0.0472 0.67 0.297 0.0631 1.06 1.2258 0.9763 3123134 ChemDiv3_014665 CCC(C)NC(=O)c1ccc(CS(=O)Cc2ccc(C)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K14 compound treatment 0.288 0.0532 0.76 0.297 0.0631 1.06 1.2864 0.9868 3123135 ChemDiv3_014666 COc1ccc(OCC(=O)N(Cc2nc(no2)c3ccccc3)C4CCCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K15 compound treatment 0.299 0.0642 0.92 0.28 0.0461 0.77 1.1959 0.9964 3040453 ChemDiv3_014667 Cc1c(CNC2CCCc3ccccc23)c(C(=O)O)c(C)n1Cc4c(F)cccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K16 compound treatment 0.269 0.0342 0.49 0.286 0.0521 0.87 0.9637 0.9622 3123136 ChemDiv3_014668 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)N2CCCC(C2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K17 compound treatment 0.24 0.00516 0.07 0.242 0.00809 0.14 0.1482 0.9588 3123137 ChemDiv3_014669 Clc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3C/C=C/c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K18 compound treatment 0.295 0.0602 0.86 0.296 0.0621 1.04 1.3454 0.9955 3040454 ChemDiv3_014670 CN(C(=O)[C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K19 compound treatment 0.247 0.0122 0.17 0.268 0.0341 0.57 0.5276 0.8821 3123138 ChemDiv3_014671 Cc1cc(C)c2c(CC(=O)Nc3c(oc4ccccc34)C(=O)Nc5cccc(Cl)c5)coc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K20 compound treatment 0.235 1.56E-4 0.0 0.268 0.0341 0.57 0.4062 0.7099 1613577 ChemDiv3_014672 CCSc1nnc2c(=O)[nH]c(=O)[nH]c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K21 compound treatment 0.305 0.0702 1.0 0.301 0.0671 1.13 1.5059 0.9983 1666742 ChemDiv3_014673 O=C(Nc1ccccc1)N2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K22 compound treatment 0.07 -0.165 -2.36 0.081 -0.153 -2.57 -3.482 -0.9991 3040455 ChemDiv3_014674 Cc1c(CCC(=O)O)c(=O)oc2cc3occ(c4ccccc4)c3cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K23 mock treatment 0.229 -0.00584 -0.08 0.248 0.0141 0.24 0.1082 0.4311 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 K24 mock treatment 0.226 -0.00884 -0.13 0.237 0.00309 0.05 -0.0527 -0.3856 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L01 compound treatment 0.253 0.0182 0.26 0.234 9.38E-5 0.0 0.1847 0.7114 3123139 ChemDiv3_014675 COc1ccc(cc1)c2coc3cc4oc(=O)c5CCCCCc5c4cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L02 compound treatment 0.244 0.00916 0.13 0.291 0.0571 0.96 0.7702 0.7963 3123140 ChemDiv3_014676 CC1=C(SCCO1)C(=O)Nc2ccc(CC(=O)N3CCC4(CC3)OCCO4)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L03 compound treatment 0.265 0.0302 0.43 0.247 0.0131 0.22 0.4604 0.951 3040456 ChemDiv3_014677 Cc1c2OCN(CCc3ccc(F)cc3)Cc2cc4c5CCCCc5c(=O)oc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L04 compound treatment 0.265 0.0302 0.43 0.277 0.0431 0.72 0.8164 0.9695 3123141 ChemDiv3_014678 Cc1cc(CN2CCN(Cc3ccccc3)CC2)cs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L05 compound treatment 0.287 0.0522 0.75 0.261 0.0271 0.45 0.8491 0.9718 3123142 ChemDiv3_014679 CCOc1ccc2oc(=O)cc(CN(CC3CCCO3)Cc4ccco4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L06 compound treatment 0.294 0.0592 0.85 0.285 0.0511 0.86 1.2047 1.0 1010838 ChemDiv3_014680 CCOC(=O)c1cnc(SC)nc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L07 compound treatment 0.27 0.0352 0.5 0.299 0.0651 1.09 1.1281 0.938 3040457 ChemDiv3_014681 COc1ccc2oc(=O)cc(CN(C)Cc3ccco3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L08 compound treatment 0.296 0.0612 0.87 0.31 0.0761 1.28 1.5216 0.983 3123143 ChemDiv3_014682 CC(C)n1c(=O)n(Cc2ccccc2)c3c4ccccc4oc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L09 compound treatment 0.287 0.0522 0.75 0.286 0.0521 0.87 1.1458 0.9969 3123144 ChemDiv3_014683 CCCN(Cc1cccs1)C(=O)NC2(CC3CC4CC(C3)C2)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L10 compound treatment 0.295 0.0602 0.86 0.3 0.0661 1.11 1.3928 0.9921 3040458 ChemDiv3_014684 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N4CCCC(C4)C(=O)Nc5ccc(C)cn5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L11 compound treatment 0.274 0.0392 0.56 0.29 0.0561 0.94 1.0618 0.9692 3123145 ChemDiv3_014685 CCc1nnc2sc(NC(=O)c3ccco3)nn12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L12 compound treatment 0.309 0.0742 1.06 0.28 0.0461 0.77 1.2971 0.988 3123146 ChemDiv3_014686 Cn1c(=O)c2sccc2n3c(CCCC(=O)N4CCCCC4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L13 compound treatment 0.298 0.0632 0.9 0.295 0.0611 1.03 1.3638 0.998 3040459 ChemDiv3_014687 CCn1c2ccccc2c3nnc(nc13)N4CCC(C)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L14 compound treatment 0.246 0.0112 0.16 0.292 0.0581 0.98 0.8023 0.812 3123147 ChemDiv3_014688 Cc1ccccc1n2c(SCC(=O)N(CC=C)c3ccccc3)nnc2c4cc5occc5n4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L15 compound treatment 0.288 0.0532 0.76 0.299 0.0651 1.09 1.3102 0.9843 3040460 ChemDiv3_014689 O=C(CCCn1c(=O)c2cccn2c3ccccc13)N4CCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L16 compound treatment 0.296 0.0612 0.87 0.305 0.0711 1.19 1.4623 0.9883 3123324 ChemDiv3_014690 CCN(Cc1ccccc1)C(=O)CSc2nc3cccnc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L17 compound treatment 0.299 0.0642 0.92 0.307 0.0731 1.23 1.5164 0.9898 3040461 ChemDiv3_014691 CCCNS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L18 compound treatment 0.31 0.0752 1.08 0.32 0.0861 1.44 1.7819 0.9894 3123325 ChemDiv3_014692 CC(C)CCNc1ncnc2n3CCCCCc3nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L19 compound treatment 0.286 0.0512 0.73 0.307 0.0731 1.23 1.3849 0.9695 3123326 ChemDiv3_014693 CC(NC(=O)C1CCCN(C1)S(=O)(=O)N2CCCCC2)C3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L20 compound treatment 0.252 0.0172 0.25 0.197 -0.0369 -0.62 -0.2645 -0.397 3040462 ChemDiv3_014694 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)Cc4cccs4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L21 compound treatment 0.312 0.0772 1.1 0.291 0.0571 0.96 1.458 0.9975 3123327 ChemDiv3_014695 Cc1cc(C)cc(NC(=O)CCCn2c(=O)c3cccn3c4cccnc24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L22 compound treatment 0.262 0.0272 0.39 0.237 0.00309 0.05 0.3114 0.7946 3040463 ChemDiv3_014696 CC(C)NC(=O)C1=Cc2sc(C)c(C)c2CS1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L23 mock treatment 0.25 0.0152 0.22 0.254 0.0201 0.34 0.3918 0.9772 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 L24 mock treatment 0.239 0.00416 0.06 0.206 -0.0279 -0.47 -0.2892 -0.6124 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M01 compound treatment 0.271 0.0362 0.52 0.295 0.0611 1.03 1.0908 0.9498 3123328 ChemDiv3_014697 OC(=O)CCc1nnc2ccc(Cl)nn12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M02 compound treatment 0.276 0.0412 0.59 0.255 0.0211 0.35 0.6666 0.9704 3123329 ChemDiv3_014698 COc1ccc(/C=C/C(=O)Nc2noc3ccccc23)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M03 compound treatment 0.262 0.0272 0.39 0.277 0.0431 0.72 0.7861 0.9575 3040464 ChemDiv3_014699 CC(CCc1ccccc1)NC(=O)CCc2nnc3ccc(nn23)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M04 compound treatment 0.311 0.0762 1.09 0.252 0.0181 0.3 0.985 0.871 3123330 ChemDiv3_014700 Cc1c(OCc2ccccc2)ccc3c(cc(=O)oc13)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M05 compound treatment 0.29 0.0552 0.79 0.275 0.0411 0.69 1.0456 0.9978 3123331 ChemDiv3_014701 Cc1ccc(CNC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M06 compound treatment 0.247 0.0122 0.17 0.25 0.0161 0.27 0.314 0.9773 3040465 ChemDiv3_014702 Brc1ccccc1c2nnc3SCC(=O)Nn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M07 compound treatment 0.286 0.0512 0.73 0.287 0.0531 0.89 1.1475 0.9952 3040466 ChemDiv3_014703 CN(C)c1nc2ccc3oc(C(=O)O)c(C)c3c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M08 compound treatment 0.323 0.0882 1.26 0.303 0.0691 1.16 1.7116 0.9991 3123332 ChemDiv3_014704 CCCNc1nc(SCc2ccc(Cl)cc2)nnc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M09 compound treatment 0.276 0.0412 0.59 0.316 0.0821 1.38 1.3906 0.9281 3123333 ChemDiv3_014705 CN1CCC2(CC1)SCC(N2C(=O)C)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M10 compound treatment 0.057 -0.178 -2.54 0.083 -0.151 -2.53 -3.5897 -1.0 1635462 ChemDiv3_014706 C(Nc1ccc2c3[nH]c4ccccc4c3ccc2n1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M11 compound treatment 0.301 0.0662 0.95 0.284 0.0501 0.84 1.2636 0.9983 3123334 ChemDiv3_014707 COc1ccc(cc1)C(=O)Cn2ccnc2C(=O)NCc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M12 compound treatment 0.293 0.0582 0.83 0.297 0.0631 1.06 1.337 0.9929 3040467 ChemDiv3_014708 Cc1ccc2CCC(CNC(=N)N)Nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M13 compound treatment 0.288 0.0532 0.76 0.307 0.0731 1.23 1.4051 0.9735 3123335 ChemDiv3_014709 COC(=O)CCSc1ccc(cc1N)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M14 compound treatment 0.231 -0.00384 -0.05 0.247 0.0131 0.22 0.1165 0.5144 3123336 ChemDiv3_014710 O=C(N(Cc1nc(no1)c2ccccc2)C3CCCCC3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M15 compound treatment 0.273 0.0382 0.55 0.284 0.0501 0.84 0.9804 0.9781 3040468 ChemDiv3_014711 Cc1c(CNCCc2cccs2)c(C(=O)O)c(C)n1Cc3c(F)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M16 compound treatment 0.284 0.0492 0.7 0.287 0.0531 0.89 1.1273 0.9931 3123337 ChemDiv3_014712 O=S(=O)(c1ccccc1)n2nc(nc2NCc3cccs3)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M17 compound treatment 0.229 -0.00584 -0.08 0.182 -0.0519 -0.87 -0.6751 -0.7714 3123338 ChemDiv3_014713 CCOc1ccccc1N2CC(CC2=O)c3nc4ccccc4n3CCCOc5c(C)cccc5C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M18 compound treatment 0.264 0.0292 0.42 0.3 0.0661 1.11 1.0793 0.9107 3040469 ChemDiv3_014714 CCCN(C(=O)[C@H]1[C@H]2C[C@H]3OC(=O)[C@@H]1[C@H]3C2)c4ccccc4OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M19 compound treatment 0.268 0.0332 0.47 0.302 0.0681 1.14 1.1435 0.9241 3123339 ChemDiv3_014715 CC(C)c1ccc2occ(CC(=O)Nc3ccc(C)cc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M20 compound treatment 0.278 0.0432 0.62 0.278 0.0441 0.74 0.9598 0.9959 3040470 ChemDiv3_014716 O=C1NN=CC(N1)(c2c[nH]c3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M21 compound treatment 0.282 0.0472 0.67 0.242 0.00809 0.14 0.573 0.8328 1353075 ChemDiv3_014717 CC(C)(NC(=O)Nc1ccccc1)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M22 compound treatment 0.214 -0.0208 -0.3 0.155 -0.0789 -1.32 -1.1473 -0.8451 3123340 ChemDiv3_014718 Cc1c(CCC(=O)O)c(=O)oc2cc3oc4CCCCc4c3cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M23 mock treatment 0.233 -0.00184 -0.03 0.243 0.00909 0.15 0.0893 0.5764 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 M24 mock treatment 0.245 0.0102 0.15 0.206 -0.0279 -0.47 -0.2285 -0.4659 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N01 compound treatment 0.262 0.0272 0.39 0.266 0.0321 0.54 0.6556 0.9871 3040471 ChemDiv3_014719 Cc1coc2cc3oc(=O)c(cc3cc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N02 compound treatment 0.268 0.0332 0.47 0.261 0.0271 0.45 0.6569 0.9998 3123341 ChemDiv3_014720 CN(Cc1csc2CCCCc12)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N03 compound treatment 0.318 0.0832 1.19 0.277 0.0431 0.72 1.3525 0.9716 3123342 ChemDiv3_014721 COc1ccc(CCN2COc3c(C)c4oc(=O)cc(c5ccccc5)c4cc3C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N04 compound treatment 0.292 0.0572 0.82 0.289 0.0551 0.92 1.2319 0.9981 3040472 ChemDiv3_014722 OCc1cc2CCCCc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N05 compound treatment 0.275 0.0402 0.57 0.277 0.0431 0.72 0.9176 0.9935 3040528 ChemDiv3_014723 CCOc1ccc2oc(=O)cc(CN(Cc3ccco3)C4CCCC4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N06 compound treatment 0.311 0.0762 1.09 0.305 0.0711 1.19 1.614 0.999 3040529 ChemDiv3_014724 NCCc1csc2CCCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N07 compound treatment 0.273 0.0382 0.55 0.302 0.0681 1.14 1.1941 0.9428 3040530 ChemDiv3_014725 COCCN(Cc1cccs1)Cc2cc(=O)oc3ccc(OC)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N08 compound treatment 0.26 0.0252 0.36 0.305 0.0711 1.19 1.0982 0.8811 3040531 ChemDiv3_014726 CCCCn1c(=O)n(CC(=O)N)c2c3ccccc3oc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N09 compound treatment 0.295 0.0602 0.86 0.277 0.0431 0.72 1.1199 0.9963 3040532 ChemDiv3_014727 CCc1ccc(CN(Cc2c[nH]nc2c3ccc(OC)cc3)C(=O)NCc4ccc(C)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N10 compound treatment 0.304 0.0692 0.99 0.272 0.0381 0.64 1.1516 0.9777 3040533 ChemDiv3_014728 Cc1ccc(cc1)S(=O)(=O)c2c(O)c3ccc(cc3[nH]c2=O)C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N11 compound treatment 0.301 0.0662 0.95 0.271 0.0371 0.62 1.1094 0.9794 3040534 ChemDiv3_014729 O=C(Nc1nn2c(nnc2s1)c3ccco3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N12 compound treatment 0.292 0.0572 0.82 0.289 0.0551 0.92 1.2319 0.9981 3123343 ChemDiv3_014730 CSc1ccc(CCNC(=O)c2oc3cc4sc(nc4cc3c2C)N(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N13 compound treatment 0.306 0.0712 1.02 0.264 0.0301 0.51 1.0768 0.9477 3123344 ChemDiv3_014731 CCn1c2ccccc2c3nnc(NCCN4CCN(CC4)c5cc(Cl)ccc5C)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N14 compound treatment 0.249 0.0142 0.2 0.265 0.0311 0.52 0.5122 0.915 3040535 ChemDiv3_014732 CCC(Sc1nnc(c2cc3occc3n2C)n1c4ccccc4C)C(=O)Nc5ccc(C)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N15 compound treatment 0.315 0.0802 1.15 0.3 0.0661 1.11 1.5951 0.9999 3123345 ChemDiv3_014733 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NCc4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N16 compound treatment 0.301 0.0662 0.95 0.284 0.0501 0.84 1.2636 0.9983 3123346 ChemDiv3_014734 CCC(C(=O)NCc1ccco1)n2c(SCc3ccc(F)cc3)nc4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N17 compound treatment 0.274 0.0392 0.56 0.22 -0.0139 -0.23 0.231 0.3807 3040536 ChemDiv3_014735 CCCN(C(=O)C1C(N(CC(C)C)C(=O)c2ccccc12)c3cccs3)c4ccccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N18 compound treatment 0.221 -0.0138 -0.2 0.145 -0.0889 -1.49 -1.1952 -0.794 3123347 ChemDiv3_014736 C(Nc1ncnc2n3CCCCCc3nc12)c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N19 compound treatment 0.29 0.0552 0.79 0.298 0.0641 1.08 1.3185 0.9884 3123348 ChemDiv3_014737 O=C(NCCCN1CCN(CC1)C2CCCCC2)C3CCCN(C3)S(=O)(=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N20 compound treatment 0.305 0.0702 1.0 0.303 0.0691 1.16 1.5296 0.9974 3040537 ChemDiv3_014738 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)c4ccccn4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N21 compound treatment 0.261 0.0262 0.37 0.258 0.0241 0.4 0.5505 0.9992 3123349 ChemDiv3_014739 Cc1c(oc2ccc3OC4(CCCC4)C=Cc3c12)C(=O)NCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N22 compound treatment 0.225 -0.00984 -0.14 0.216 -0.0179 -0.3 -0.3121 -0.9403 3040538 ChemDiv3_014740 Cc1sc2C=C(SCc2c1C)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N23 mock treatment 0.21 -0.0248 -0.36 0.259 0.0251 0.42 0.0465 0.0845 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 N24 mock treatment 0.252 0.0172 0.25 0.227 -0.00691 -0.12 0.0916 0.3374 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O01 compound treatment 0.259 0.0242 0.35 0.266 0.0321 0.54 0.6252 0.977 3040539 ChemDiv3_014741 NNc1ccc2nncn2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O02 compound treatment 0.274 0.0392 0.56 0.278 0.0441 0.74 0.9193 0.9906 3123350 ChemDiv3_014742 O=C(Cc1cccs1)Nc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O03 compound treatment 0.292 0.0572 0.82 0.285 0.0511 0.86 1.1845 0.9997 3123351 ChemDiv3_014743 COC(=O)c1ccc2oc(=O)c(cc2c1)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O04 compound treatment 0.293 0.0582 0.83 0.302 0.0681 1.14 1.3963 0.9878 1527932 ChemDiv3_014744 CC(C)C(=O)Oc1ccc2c(C)cc(=O)oc2c1C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O05 compound treatment 0.275 0.0402 0.57 0.264 0.0301 0.51 0.7633 0.9979 3120289 ChemDiv3_014745 CCNc1cc(N2CCCC2)c3noc4-c5ccccc5C(=O)c1c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O06 compound treatment 0.213 -0.0218 -0.31 0.234 9.38E-5 0.0 -0.2198 -0.7035 3040540 ChemDiv3_014746 O=C1CSc2nnc(C3COc4ccccc4O3)n2N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O07 compound treatment 0.285 0.0502 0.72 0.275 0.0411 0.69 0.995 0.9998 3120290 ChemDiv3_014747 CCOC(=O)c1oc2cc3sc(nc3cc2c1C)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O08 compound treatment 0.221 -0.0138 -0.2 0.282 0.0481 0.81 0.4308 0.5183 3040541 ChemDiv3_014748 Cn1c(nc2ccccc12)C3=C(N)N(CC3=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O09 compound treatment 0.241 0.00616 0.09 0.26 0.0261 0.44 0.3719 0.8326 3120291 ChemDiv3_014749 CCOC(=O)c1c(NC(=O)C)c2c3CCCCc3sc2n1Cc4ccc(F)cc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O10 compound treatment 0.285 0.0502 0.72 0.277 0.0431 0.72 1.0187 1.0 1355670 ChemDiv3_014750 CC(=O)Nc1ccc2nc3c(cc2c1)[nH]c4ccccc43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O11 compound treatment 0.266 0.0312 0.45 0.237 0.00309 0.05 0.3518 0.7842 3040542 ChemDiv3_014751 CCN(c1ccccc1)S(=O)(=O)N2CCCC(C2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O12 compound treatment 0.231 -0.00384 -0.05 0.276 0.0421 0.71 0.4607 0.6501 1569429 ChemDiv3_014752 CN(C)CCn1c(=O)n(C)c2nc[nH]c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O13 compound treatment 0.246 0.0112 0.16 0.252 0.0181 0.3 0.3276 0.9549 3040543 ChemDiv3_014753 OC(=O)C1=C(OCCS1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O14 compound treatment 0.255 0.0202 0.29 0.251 0.0171 0.29 0.4067 1.0 3120292 ChemDiv3_014754 CC(C)(C)C(=O)N(Cc1nc(no1)c2ccccc2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O15 compound treatment 0.262 0.0272 0.39 0.264 0.0301 0.51 0.6318 0.9916 3120293 ChemDiv3_014755 Cc1c(CNCCC2=CCCCC2)c(C(=O)O)c(C)n1Cc3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O16 compound treatment 0.231 -0.00384 -0.05 0.269 0.0351 0.59 0.3776 0.6383 3040544 ChemDiv3_014756 COc1ccc(CNc2nc(nn2S(=O)(=O)C)c3cccnc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O17 compound treatment 0.255 0.0202 0.29 0.241 0.00709 0.12 0.2881 0.9235 3040545 ChemDiv3_014757 CC(O)c1nc2cc(C)ccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O18 compound treatment 0.26 0.0252 0.36 0.266 0.0321 0.54 0.6353 0.9808 3120294 ChemDiv3_014758 CC(C)N(Cc1cccs1)C(=O)[C@H]2[C@H]3C[C@H]4OC(=O)[C@@H]2[C@H]4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O19 compound treatment 0.211 -0.0238 -0.34 0.189 -0.0449 -0.75 -0.7741 -0.9357 3120295 ChemDiv3_014759 C=CCn1c2ccccc2c3nnc(SCC(=O)NC4=NN=C(CS4)c5ccccc5)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O20 compound treatment 0.05 -0.185 -2.64 0.048 -0.186 -3.12 -4.0759 -0.9966 3040546 ChemDiv3_014760 Cc1cc(C)c(C(=O)CC(N2CCCCC2)C(F)(F)F)c(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O21 compound treatment 0.256 0.0212 0.3 0.247 0.0131 0.22 0.3694 0.9877 3120296 ChemDiv3_014761 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)Nn3cnnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O22 compound treatment 0.218 -0.0168 -0.24 0.211 -0.0229 -0.38 -0.4422 -0.9747 3040547 ChemDiv3_014762 Cc1c(CC(=O)O)c(=O)oc2c(C)c3occ(c3cc12)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O23 mock treatment 0.237 0.00216 0.03 0.234 9.38E-5 0.0 0.0229 0.7422 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 O24 mock treatment 0.253 0.0182 0.26 0.211 -0.0229 -0.38 -0.0882 -0.1901 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P01 compound treatment 0.254 0.0192 0.27 0.25 0.0161 0.27 0.3848 1.0 3120297 ChemDiv3_014763 Cc1ccc(CN2COc3c(Cl)cc4c(C)c(C)c(=O)oc4c3C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P02 compound treatment 0.252 0.0172 0.25 0.277 0.0431 0.72 0.685 0.8968 3040548 ChemDiv3_014764 C(N1CCc2ccccc12)c3csc4CCCCc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P03 compound treatment 0.255 0.0202 0.29 0.252 0.0181 0.3 0.4186 0.9997 3120298 ChemDiv3_014765 Cc1c(CCC(=O)NCc2ccccc2)c(=O)oc3cc(O)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P04 compound treatment 0.27 0.0352 0.5 0.291 0.0571 0.96 1.0332 0.9547 3040549 ChemDiv3_014766 CCCN(CCC)Cc1csc2CCCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P05 compound treatment 0.281 0.0462 0.66 0.283 0.0491 0.82 1.0495 0.994 3120299 ChemDiv3_014767 CN(Cc1cc(=O)oc2cc(C)ccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P06 compound treatment 0.261 0.0262 0.37 0.284 0.0501 0.84 0.8591 0.9335 3040550 ChemDiv3_014768 Cc1cc(CSC(=N)N)cs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P07 compound treatment 0.247 0.0122 0.17 0.22 -0.0139 -0.23 -0.0421 -0.1446 3120300 ChemDiv3_014769 COc1ccc2oc(=O)cc(CN(Cc3cccs3)C(C)C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P08 compound treatment 0.289 0.0542 0.77 0.282 0.0481 0.81 1.1185 0.9998 3040551 ChemDiv3_014770 Cc1ccc(Cn2c(=O)n(c3ccc(C)c(C)c3)c(=O)c4oc5ccccc5c24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P09 compound treatment 0.261 0.0262 0.37 0.259 0.0251 0.42 0.5624 0.9983 3120301 ChemDiv3_014771 Clc1ccc2n(ncc2c1)C(=O)NC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P10 compound treatment 0.27 0.0352 0.5 0.261 0.0271 0.45 0.6771 0.9987 3120302 ChemDiv3_014772 O=C(CCNS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P11 compound treatment 0.262 0.0272 0.39 0.273 0.0391 0.66 0.7386 0.9687 3040552 ChemDiv3_014773 CCCc1nnc2sc(NC(=O)CC)nn12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P12 compound treatment 0.251 0.0162 0.23 0.253 0.0191 0.32 0.39 0.9871 3120303 ChemDiv3_014774 CN(C)c1nc2ccc3oc(C(=O)NCCCN4CCCCCC4)c(C)c3c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P13 compound treatment 0.296 0.0612 0.87 0.238 0.00409 0.07 0.6671 0.7603 3040553 ChemDiv3_014775 CCn1c2ccccc2c3nnc(NCCOc4cccc(c4)C(F)(F)F)nc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P14 compound treatment 0.31 0.0752 1.08 0.235 0.00109 0.02 0.7731 0.7191 3120304 ChemDiv3_014776 COc1ccc(Cl)cc1n2c(SCc3cccc(Cl)c3)nnc2c4cc5occc5n4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P15 compound treatment 0.286 0.0512 0.73 0.283 0.0491 0.82 1.1001 0.9982 3040554 ChemDiv3_014777 O=C(CCCn1c(=O)c2cccn2c3ccccc13)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P16 compound treatment 0.272 0.0372 0.53 0.283 0.0491 0.82 0.9585 0.9775 3120305 ChemDiv3_014778 CCC(C(=O)Nc1cccc(OC)c1)n2c(SCc3ccc(C)cc3)nc4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P17 compound treatment 0.272 0.0372 0.53 0.26 0.0261 0.44 0.6855 0.9954 3120306 ChemDiv3_014779 CCC(C)NC(=O)C1CCN(CC1)S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P18 compound treatment 0.25 0.0152 0.22 0.265 0.0311 0.52 0.5223 0.9243 3040555 ChemDiv3_014780 CCOc1ccccc1CNc2ncnc3n4CCCCCc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P19 compound treatment 0.266 0.0312 0.45 0.277 0.0431 0.72 0.8266 0.9729 3120307 ChemDiv3_014781 COc1ccc2c(CNCC(C)c3ccccc3)c(C(=O)O)n(Cc4ccc(F)cc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P20 compound treatment 0.047 -0.188 -2.69 0.103 -0.131 -2.2 -3.4535 -0.995 3040556 ChemDiv3_014782 Cc1cc(Nc2cccc(c2)C(F)(F)F)nc3ccc(NC(=O)CSc4ccncc4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P21 compound treatment 0.322 0.0872 1.25 0.268 0.0341 0.57 1.2861 0.9376 3120308 ChemDiv3_014783 Cc1c(oc2ccc3OC4(CCCC4)C=Cc3c12)C(=O)NC5CCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P22 compound treatment 0.157 -0.0778 -1.11 0.129 -0.105 -1.76 -2.0324 -0.9756 3120309 ChemDiv3_014784 O=C(NCc1ccccc1)C2=Cc3sc4CCCCc4c3CS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P23 mock treatment 0.279 0.0442 0.63 0.274 0.0401 0.67 0.9224 0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2042 P24 mock treatment 0.231 -0.00384 -0.05 0.242 0.00809 0.14 0.0572 0.3902 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A01 compound treatment 0.198 -0.0276 -0.4 0.233 0.0162 0.27 -0.0871 -0.1815 3040557 ChemDiv3_014785 O=C(NCCN1CCCC1)C2=Cc3sc4CCCCc4c3CS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A02 compound treatment 0.224 -0.00165 -0.02 0.255 0.0382 0.64 0.4369 0.6807 1691169 ChemDiv3_014786 O=C(Nc1ccccc1C(=O)N2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A03 compound treatment 0.215 -0.0106 -0.15 0.232 0.0152 0.26 0.0729 0.2453 3040558 ChemDiv3_014787 CCC(C)NS(=O)(=O)c1ccc(cc1)n2cccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A04 compound treatment 0.224 -0.00165 -0.02 0.232 0.0152 0.26 0.164 0.6393 1301241 ChemDiv3_014788 CCNc1c2C(=O)CC(C)(C)Cc2nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A05 compound treatment 0.216 -0.00965 -0.14 0.226 0.00922 0.15 0.0119 0.0572 3120310 ChemDiv3_014789 O=S(=O)(Nc1ccc(cc1)c2ccno2)c3ccc(cc3)n4cccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A06 compound treatment 0.247 0.0214 0.31 0.228 0.0112 0.19 0.3491 0.973 1714116 ChemDiv3_014790 Cc1cc(O)n(CCc2ccccc2)c(=O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A07 compound treatment 0.209 -0.0166 -0.24 0.179 -0.0378 -0.63 -0.6167 -0.9105 3120311 ChemDiv3_014791 CCOC(=O)c1cc(C)n(CC2CCC(CC2)C(=O)Nc3ccccc3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A08 compound treatment 0.226 3.55E-4 0.01 0.195 -0.0218 -0.37 -0.2549 -0.6972 3040559 ChemDiv3_014792 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A09 compound treatment 0.224 -0.00165 -0.02 0.224 0.00722 0.12 0.069 0.5593 3120312 ChemDiv3_014793 CN(Cc1ccccc1)C(=O)c2cc(n[nH]2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A10 compound treatment 0.244 0.0184 0.26 0.227 0.0102 0.17 0.3069 0.9787 1387657 ChemDiv3_014794 COc1ccccc1C2(CC(=O)O)CCOC(C)(C)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A11 compound treatment 0.215 -0.0106 -0.15 0.202 -0.0148 -0.25 -0.2831 -0.9725 3040560 ChemDiv3_014795 CN1CCC2(CC1)SCC(N2C(=O)C)C(=O)NCc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A12 compound treatment 0.225 -6.45E-4 -0.01 0.192 -0.0248 -0.42 -0.3006 -0.7226 1163694 ChemDiv3_014796 CCOC(=O)C(C#N)C1(CCOC(C)(C)C1)c2ccccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A13 compound treatment 0.2 -0.0256 -0.37 0.186 -0.0308 -0.52 -0.6247 -0.9859 3040561 ChemDiv3_014797 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2c(C)n(C)c(=O)n(C)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A14 compound treatment 0.221 -0.00465 -0.07 0.217 2.19E-4 0.0 -0.0444 -0.667 1604258 ChemDiv3_014798 Cc1cc(OCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)cc(C)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A15 compound treatment 0.206 -0.0196 -0.28 0.213 -0.00378 -0.06 -0.2436 -0.8455 1918523 ChemDiv3_014799 Cc1nc2cc(CCO)ccc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A16 compound treatment 0.221 -0.00465 -0.07 0.222 0.00522 0.09 0.015 0.136 3040562 ChemDiv3_014800 CN/1CCCCC\C1=N\c2cccc(F)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A17 compound treatment 0.197 -0.0286 -0.41 0.225 0.00822 0.14 -0.1922 -0.4445 1448263 ChemDiv3_014801 CC(=C)C1Cc2nc(N)nc(C)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A18 compound treatment 0.241 0.0154 0.22 0.226 0.00922 0.15 0.2647 0.9853 3120490 ChemDiv3_014802 COc1ccc(CNc2cc(C)ccn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A19 compound treatment 0.217 -0.00865 -0.12 0.208 -0.00878 -0.15 -0.1917 -0.9962 1082159 ChemDiv3_014803 CCNC(=O)Nc1nc2ccccc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A20 compound treatment 0.215 -0.0106 -0.15 0.2 -0.0168 -0.28 -0.3068 -0.9583 3040619 ChemDiv3_014804 Cc1ccc2[nH]c(nc2c1)C(O)C(O)c3nc4cc(C)ccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A21 compound treatment 0.192 -0.0336 -0.48 0.232 0.0152 0.26 -0.1597 -0.2931 1518446 ChemDiv3_014805 COc1ccc(OCC(O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A22 compound treatment 0.2 -0.0256 -0.37 0.213 -0.00378 -0.06 -0.3043 -0.8173 1354832 ChemDiv3_014806 COc1cc2C(C)NCC3(CCCC3)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A23 mock treatment 0.226 3.55E-4 0.01 0.21 -0.00678 -0.11 -0.0769 -0.6749 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 A24 mock treatment 0.199 -0.0266 -0.38 0.211 -0.00578 -0.1 -0.3381 -0.8597 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B01 compound treatment 0.232 0.00635 0.09 0.219 0.00222 0.04 0.0906 0.9224 3040620 ChemDiv3_014807 CCOc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nn4c(C)nnc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B02 compound treatment 0.249 0.0234 0.33 0.241 0.0242 0.41 0.5236 0.9953 3040621 ChemDiv3_014808 CCOc1cc(C)c(Cl)cc1S(=O)(=O)Nc2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B03 compound treatment 0.247 0.0214 0.31 0.212 -0.00478 -0.08 0.1592 0.5042 3040622 ChemDiv3_014809 CCCN(c1ccccc1C(=O)O)S(=O)(=O)c2ccc3n(C)c(=O)n(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B04 compound treatment 0.245 0.0194 0.28 0.245 0.0282 0.47 0.5307 0.9673 1448023 ChemDiv3_014810 COc1ccc2n(C)c(COc3ccccc3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B05 compound treatment 0.228 0.00235 0.03 0.246 0.0292 0.49 0.3706 0.7539 3120491 ChemDiv3_014811 OC(CN1CCCCC1)Cn2ccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B06 compound treatment 0.244 0.0184 0.26 0.235 0.0182 0.31 0.4019 0.9971 3040623 ChemDiv3_014812 O=c1nc(NCc2ccco2)cc[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B07 compound treatment 0.233 0.00735 0.11 0.243 0.0262 0.44 0.3856 0.8521 3120492 ChemDiv3_014813 Cc1ccnc(NC(=O)CCC2COc3ccccc3O2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B08 compound treatment 0.243 0.0174 0.25 0.241 0.0242 0.41 0.463 0.972 3120493 ChemDiv3_014814 COc1cccc(c1)c2cc(n3ncc(C(=O)NC4CCCC4)c3n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B09 compound treatment 0.225 -6.45E-4 -0.01 0.217 2.19E-4 0.0 -0.0039 -0.3956 3040624 ChemDiv3_014815 CCc1nnc(s1)N2CCN(CC2)c3ncnc4c5ccccc5oc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B10 compound treatment 0.226 3.55E-4 0.01 0.226 0.00922 0.15 0.113 0.7299 3120494 ChemDiv3_014816 CCC1CCCCN1C(=O)c2cc(on2)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B11 compound treatment 0.246 0.0204 0.29 0.226 0.00922 0.15 0.3153 0.9562 3120495 ChemDiv3_014817 Cc1cc(C)nc(n1)N2C(=O)CC(N=C2NCCc3c[nH]c4ccccc34)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B12 compound treatment 0.242 0.0164 0.23 0.217 2.19E-4 0.0 0.168 0.7181 3040625 ChemDiv3_014818 CC1(C)CC(=Nc2ccccc2N1)/C=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B13 compound treatment 0.226 3.55E-4 0.01 0.181 -0.0358 -0.6 -0.4211 -0.7011 3040626 ChemDiv3_014819 CC1(C)COC(=N1)N(C(=O)NC2CCCCC2)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B14 compound treatment 0.186 -0.0396 -0.57 0.162 -0.0548 -0.92 -1.0511 -0.973 3120496 ChemDiv3_014820 O=C1CC(=NN1c2nc3ccccc3[nH]2)CSc4nnnn4c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B15 compound treatment 0.233 0.00735 0.11 0.221 0.00422 0.07 0.1245 0.9814 3120497 ChemDiv3_014821 CCOc1cc(CNC2CN3CCC2CC3)ccc1OCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B16 compound treatment 0.253 0.0274 0.39 0.229 0.0122 0.21 0.4217 0.9546 3040627 ChemDiv3_014822 COc1cc(NC(=O)C2CC(=O)NC3=C2C(=O)CC(C)(C)C3)c(OC)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B17 compound treatment 0.238 0.0124 0.18 0.243 0.0262 0.44 0.4361 0.9197 3120498 ChemDiv3_014823 CC1SC(=NC1=O)NC(=O)CSc2nc(C)cc(C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B18 compound treatment 0.242 0.0164 0.23 0.237 0.0202 0.34 0.4054 0.9835 3120499 ChemDiv3_014824 COC(=O)C1=NOC2(CC(=O)N(C2=O)c3ccc(Cl)cc3)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B19 compound treatment 0.081 -0.145 -2.07 0.069 -0.148 -2.48 -3.2169 -0.9959 3040628 ChemDiv3_014825 Cc1ccc(CNc2ccc3n(cnc3c2)C4CCCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B20 compound treatment 0.185 -0.0406 -0.58 0.14 -0.0768 -1.29 -1.3223 -0.9353 3120500 ChemDiv3_014826 CCOC(=O)Cc1sc(Nc2ccccn2)nc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B21 compound treatment 0.266 0.0404 0.58 0.226 0.00922 0.15 0.5176 0.8661 3040629 ChemDiv3_014827 COC(=O)c1ccc(OCCN2C3=NCCN3c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B22 compound treatment 0.25 0.0244 0.35 0.237 0.0202 0.34 0.4863 0.9999 3120501 ChemDiv3_014828 Cn1c(=O)cc(Nc2ccc(F)c(Cl)c2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B23 mock treatment 0.255 0.0294 0.42 0.24 0.0232 0.39 0.5725 0.9993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 B24 mock treatment 0.223 -0.00265 -0.04 0.24 0.0232 0.39 0.2488 0.6355 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C01 compound treatment 0.207 -0.0186 -0.27 0.219 0.00222 0.04 -0.1622 -0.6025 3120502 ChemDiv3_014829 CCOC(=O)c1cnc(SCC(=O)NCc2ccco2)nc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C02 compound treatment 0.198 -0.0276 -0.4 0.218 0.00122 0.02 -0.2651 -0.6696 1168895 ChemDiv3_014830 Cc1ccccc1NC(=O)Cn2nc(C)c3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C03 compound treatment 0.238 0.0124 0.18 0.233 0.0162 0.27 0.3174 0.9781 3120503 ChemDiv3_014831 O=S(=O)(NC1CCCC1)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C04 compound treatment 0.225 -6.45E-4 -0.01 0.209 -0.00778 -0.13 -0.0989 -0.7552 3040630 ChemDiv3_014832 Cc1cc(C)nc(NC(=N)Nc2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C05 compound treatment 0.223 -0.00265 -0.04 0.21 -0.00678 -0.11 -0.1072 -0.8941 3120504 ChemDiv3_014833 CCOC(=O)C1=C(CN2CCC(C)CC2)NC(=O)NC1c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C06 compound treatment 0.081 -0.145 -2.07 0.075 -0.142 -2.38 -3.1456 -0.9976 3444261 ChemDiv3_014834 CC(C)C(NC(=O)C1(CC2CC3CC(C2)C1)C3)C(=O)Nc4nc5ccccc5s4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C07 compound treatment 0.258 0.0324 0.46 0.229 0.0122 0.21 0.4723 0.933 3040631 ChemDiv3_014835 Cc1ccccc1Nc2nn3c(=O)c4ccc(cc4nc3s2)C(=O)NCCC5=CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C08 compound treatment 0.041 -0.185 -2.64 0.198 -0.0188 -0.32 -2.0904 -0.7859 1263817 ChemDiv3_014836 Cc1ccc2c(O)c(CN3CCCC3)c(C)nc2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C09 compound treatment 0.04 -0.186 -2.66 0.181 -0.0358 -0.6 -2.3023 -0.8457 3040632 ChemDiv3_014837 CN(C1CCCCC1)C(=O)c2cc(n[nH]2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C10 compound treatment 0.194 -0.0316 -0.45 0.202 -0.0148 -0.25 -0.4955 -0.9599 1272029 ChemDiv3_014838 COc1ccc(cc1)c2nc(NCC3CCCO3)c4ccccc4n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C11 compound treatment 0.226 3.55E-4 0.01 0.233 0.0162 0.27 0.1961 0.7202 3040633 ChemDiv3_014839 CCCC1Nc2ccccc2S(=O)(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C12 compound treatment 0.041 -0.185 -2.64 0.045 -0.172 -2.88 -3.9063 -0.999 1261807 ChemDiv3_014840 COc1ccccc1C2(CC#N)CCOC(C)(C)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C13 compound treatment 0.043 -0.183 -2.61 0.2 -0.0168 -0.28 -2.0465 -0.7788 3120505 ChemDiv3_014841 O=S(=O)(N1CCCC1)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C14 compound treatment 0.237 0.0114 0.16 0.247 0.0302 0.51 0.4735 0.8891 1626639 ChemDiv3_014842 COc1ccc2[nH]c3C(CC(=O)O)NCCc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C15 compound treatment 0.228 0.00235 0.03 0.212 -0.00478 -0.08 -0.0329 -0.3783 1136077 ChemDiv3_014843 COc1ccc2[nH]cc(CCN3C(=O)c4ccccc4C3=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C16 compound treatment 0.063 -0.163 -2.33 0.2 -0.0168 -0.28 -1.8442 -0.787 3120506 ChemDiv3_014844 NC(=O)c1c2NCCc2cnc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C17 compound treatment 0.223 -0.00265 -0.04 0.043 -0.174 -2.92 -2.0892 -0.7162 1388285 ChemDiv3_014845 CC(CC(=O)NCc1ccccc1)C2CCCO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C18 compound treatment 0.214 -0.0116 -0.17 0.203 -0.0138 -0.23 -0.2813 -0.987 3120507 ChemDiv3_014846 Cc1ccc(cc1)S(=O)(=O)N2CCn3c2nc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C19 compound treatment 0.202 -0.0236 -0.34 0.042 -0.175 -2.93 -2.3135 -0.7834 1718335 ChemDiv3_014847 OC1(CN2CCC1CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C20 compound treatment 0.203 -0.0226 -0.32 0.209 -0.00778 -0.13 -0.3214 -0.9202 3120508 ChemDiv3_014848 Cc1cccc(c1)C(=O)Nc2nc3cc4sc(NC(=O)c5cccc(C)c5)nc4cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C21 compound treatment 0.224 -0.00165 -0.02 0.206 -0.0108 -0.18 -0.1446 -0.7924 1426520 ChemDiv3_014849 CN(C)CCSc1nc2ccccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C22 compound treatment 0.045 -0.181 -2.58 0.057 -0.16 -2.68 -3.7234 -0.9998 3040634 ChemDiv3_014850 CCC(C)Cn1c(C)c2c(=O)n([nH]c2cc1=O)c3nc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C23 mock treatment 0.04 -0.186 -2.66 0.212 -0.00478 -0.08 -1.9344 -0.7281 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 C24 mock treatment 0.214 -0.0116 -0.17 0.202 -0.0148 -0.25 -0.2932 -0.9812 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D01 compound treatment 0.246 0.0204 0.29 0.249 0.0322 0.54 0.5882 0.9578 3120509 ChemDiv3_014851 CCOc1ccc(cc1)C2N(CC3CCCO3)C(=O)c4oc5ccc(F)cc5c(=O)c24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D02 compound treatment 0.233 0.00735 0.11 0.225 0.00822 0.14 0.1719 0.9911 3040635 ChemDiv3_014852 O=c1[nH]c(nc2CCCCc21)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D03 compound treatment 0.241 0.0154 0.22 0.252 0.0352 0.59 0.5733 0.9091 3120510 ChemDiv3_014853 CN(c1ccccc1C(=O)O)S(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D04 compound treatment 0.258 0.0324 0.46 0.204 -0.0128 -0.21 0.1756 0.3442 3120511 ChemDiv3_014854 COc1nccnc1NS(=O)(=O)c2ccc(NCc3cc(Br)ccc3O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D05 compound treatment 0.291 0.0654 0.93 0.219 0.00222 0.04 0.6873 0.7347 3040636 ChemDiv3_014855 OC(Cn1ccc2ccccc12)Cn3cnc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D06 compound treatment 0.303 0.0774 1.11 0.24 0.0232 0.39 1.0579 0.9019 3123741 ChemDiv3_014856 O=C1N(CC2CC(=NO2)c3ccccc3)S(=O)(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D07 compound treatment 0.068 -0.158 -2.25 0.064 -0.153 -2.56 -3.4077 -0.9979 3040637 ChemDiv3_014857 COc1cccc(c1)n2nnnc2S(=O)(=O)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D08 compound treatment 0.244 0.0184 0.26 0.246 0.0292 0.49 0.5324 0.9571 3123742 ChemDiv3_014858 Fc1cccc(Cl)c1C2=NOC(C2)C(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D09 compound treatment 0.241 0.0154 0.22 0.25 0.0332 0.56 0.5495 0.9171 3040638 ChemDiv3_014859 CCn1c(COc2ccccc2C(=O)N)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D10 compound treatment 0.296 0.0704 1.01 0.242 0.0252 0.42 1.0109 0.9259 3123743 ChemDiv3_014860 Cc1ccc(cc1)c2cc(no2)C(=O)NC(C)(C)CO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D11 compound treatment 0.241 0.0154 0.22 0.219 0.00222 0.04 0.1816 0.8154 3123744 ChemDiv3_014861 Cc1nc(Nc2nc3ccccc3o2)ncc1C(=O)Nc4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D12 compound treatment 0.309 0.0834 1.19 0.286 0.0692 1.16 1.6646 0.9999 3040639 ChemDiv3_014862 CN(C)c1ccc(/C=C/C2=Nc3ccccc3SC(C)(C)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D13 compound treatment 0.273 0.0474 0.68 0.271 0.0542 0.91 1.1224 0.9894 3123745 ChemDiv3_014863 CCc1ccc(NC(=O)C2CC(=O)n3c(N2)nc4ccccc34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D14 compound treatment 0.265 0.0394 0.56 0.28 0.0632 1.06 1.1483 0.956 1038239 ChemDiv3_014864 Cc1nc2ccc(cc2s1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D15 compound treatment 0.277 0.0514 0.73 0.224 0.00722 0.12 0.6051 0.8128 3040640 ChemDiv3_014865 CSc1ccc(CNC2CN3CCC2CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D16 compound treatment 0.249 0.0234 0.33 0.219 0.00222 0.04 0.2625 0.7811 3123746 ChemDiv3_014866 COc1cc(NC(=O)C2CC(=O)NC3=C2C(=O)CCC3)cc(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D17 compound treatment 0.291 0.0654 0.93 0.251 0.0342 0.57 1.0671 0.9726 3040641 ChemDiv3_014867 CCN(CC)CCn1nc(C)nc1c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D18 compound treatment 0.261 0.0354 0.51 0.236 0.0192 0.32 0.5857 0.9764 1674400 ChemDiv3_014868 CCCN1C(=O)C(O)(c2c[nH]c3ccccc23)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D19 compound treatment 0.137 -0.0886 -1.27 0.164 -0.0528 -0.89 -1.523 -0.9846 3123747 ChemDiv3_014869 COc1cccc(CNc2ccc3n(cnc3c2)C4CCCCC4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D20 compound treatment 0.238 0.0124 0.18 0.221 0.00422 0.07 0.175 0.9194 3040642 ChemDiv3_014870 COc1ccc2c3CCNC(C)(C(=O)O)c3[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D21 compound treatment 0.206 -0.0196 -0.28 0.201 -0.0158 -0.26 -0.386 -0.9996 3123748 ChemDiv3_014871 Cc1cc(ccc1NC(=O)C(C)(C)Oc2ccc(Cl)cc2)c3nc4ncccc4o3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D22 compound treatment 0.148 -0.0776 -1.11 0.116 -0.101 -1.69 -1.9814 -0.9792 3123749 ChemDiv3_014872 COc1ccccc1Nc2c3CCCCc3nc4ccc(NC(=O)COc5cccc(C)c5)cc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D23 mock treatment 0.243 0.0174 0.25 0.258 0.0412 0.69 0.6647 0.9044 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 D24 mock treatment 0.229 0.00335 0.05 0.21 -0.00678 -0.11 -0.0465 -0.3769 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E01 compound treatment 0.216 -0.00965 -0.14 0.211 -0.00578 -0.1 -0.1662 -0.9852 3040643 ChemDiv3_014873 CCOC(=O)c1cnc(SCC(=O)N(C)c2ccccc2)nc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E02 compound treatment 0.217 -0.00865 -0.12 0.194 -0.0228 -0.38 -0.3578 -0.8904 1586676 ChemDiv3_014874 CN(C)CCOC(=O)C1(CCCC1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E03 compound treatment 0.261 0.0354 0.51 0.233 0.0162 0.27 0.5501 0.9578 3123750 ChemDiv3_014875 CN(C1CCCCC1)S(=O)(=O)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E04 compound treatment 0.262 0.0364 0.52 0.238 0.0212 0.36 0.6195 0.983 1574583 ChemDiv3_014876 CCc1ccc(cc1)S(=O)(=O)N2CC(=O)Nc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E05 compound treatment 0.25 0.0244 0.35 0.22 0.00322 0.05 0.2845 0.8071 3040644 ChemDiv3_014877 CCc1ccc(cc1)N2COc3ccc4cc(C(=O)OC)c(=O)oc4c3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E06 compound treatment 0.241 0.0154 0.22 0.22 0.00322 0.05 0.1935 0.8555 3123751 ChemDiv3_014878 COc1cc2CC(C)(C)N=C(C)c2cc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E07 compound treatment 0.227 0.00135 0.02 0.215 -0.00178 -0.03 -0.0074 -0.2087 3123752 ChemDiv3_014879 Cc1ccccc1Nc2nn3c(=O)c4ccc(cc4nc3s2)C(=O)NCc5ccccc5Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E08 compound treatment 0.283 0.0574 0.82 0.251 0.0342 0.57 0.9862 0.9848 3040645 ChemDiv3_014880 COc1ccc2n3CCN(C)/C(=N\C)/c3c(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E09 compound treatment 0.237 0.0114 0.16 0.162 -0.0548 -0.92 -0.5353 -0.5733 3040646 ChemDiv3_014881 CC(C)CN(CC(C)C)C(=O)c1cc(n[nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E10 compound treatment 0.249 0.0234 0.33 0.241 0.0242 0.41 0.5236 0.9953 1286750 ChemDiv3_014882 Cc1ccc2n(CC(O)CN3C(=O)CNC3=O)c(c(c4ccccc4)c2c1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E11 compound treatment 0.284 0.0584 0.83 0.256 0.0392 0.66 1.0557 0.9931 3040647 ChemDiv3_014883 Brc1cccc(c1)C2Nc3ccccc3S(=O)(=O)N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E12 compound treatment 0.27 0.0444 0.63 0.24 0.0232 0.39 0.7242 0.9726 1123038 ChemDiv3_014884 COc1ccc2n3CCNC4CCCc(c43)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E13 compound treatment 0.253 0.0274 0.39 0.247 0.0302 0.51 0.6353 0.9918 3041041 ChemDiv3_014885 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)NCC4CCC(CC4)C(=O)Nc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E14 compound treatment 0.282 0.0564 0.81 0.249 0.0322 0.54 0.9524 0.9811 1875958 ChemDiv3_014886 CCc1[nH]c(=O)c(C#N)c2CCCCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E15 compound treatment 0.281 0.0554 0.79 0.244 0.0272 0.46 0.8829 0.9659 3041042 ChemDiv3_014887 Cc1ccc2nc(oc2c1)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E16 compound treatment 0.217 -0.00865 -0.12 0.229 0.0122 0.21 0.0576 0.2404 3041043 ChemDiv3_014888 C1CC(CCN1)c2cc([nH]n2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E17 compound treatment 0.272 0.0464 0.66 0.208 -0.00878 -0.15 0.3646 0.5368 1439469 ChemDiv3_014889 Cn1c(CNc2ccccc2)cc(=O)n(C)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E18 compound treatment 0.275 0.0494 0.71 0.232 0.0152 0.26 0.6798 0.9055 3041044 ChemDiv3_014890 Cn1nc(c2ccc(cc2)C(=O)N)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E19 compound treatment 0.251 0.0254 0.36 0.233 0.0162 0.27 0.4489 0.99 3041045 ChemDiv3_014891 Clc1ccc(NC(=O)NCCCn2ccnc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E20 compound treatment 0.244 0.0184 0.26 0.218 0.00122 0.02 0.2001 0.7599 3041046 ChemDiv3_014892 Cn1nc(C(=O)N2CCCC2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E21 compound treatment 0.127 -0.0986 -1.41 0.114 -0.103 -1.73 -2.2175 -0.995 1576461 ChemDiv3_014893 Cc1cc(C)n(CC(O)CN2c3ccccc3Sc4ccccc24)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E22 compound treatment 0.148 -0.0776 -1.11 0.148 -0.0688 -1.15 -1.6016 -0.9998 3123753 ChemDiv3_014894 COc1ccc(CCn2c(C)c3c(=O)n([nH]c3cc2=O)c4nc5ccccc5s4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E23 mock treatment 0.232 0.00635 0.09 0.216 -7.81E-4 -0.01 0.055 0.5989 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 E24 mock treatment 0.229 0.00335 0.05 0.201 -0.0158 -0.26 -0.1534 -0.5697 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F01 compound treatment 0.233 0.00735 0.11 0.225 0.00822 0.14 0.1719 0.9911 3041047 ChemDiv3_014895 COc1ccc(cc1)N(C(=O)c2ccncc2)S(=O)(=O)c3ccc(OC)c(OC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F02 compound treatment 0.239 0.0134 0.19 0.241 0.0242 0.41 0.4225 0.9407 3123754 ChemDiv3_014896 CC1CC(=O)c2cnc(Nc3ccccc3)nc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F03 compound treatment 0.259 0.0334 0.48 0.245 0.0282 0.47 0.6723 1.0 3041048 ChemDiv3_014897 CCC(=O)N(CCC1(CCOC(C)(C)C1)c2ccccc2)Cc3ccccc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F04 compound treatment 0.235 0.00935 0.13 0.269 0.0522 0.88 0.7144 0.8057 1039621 ChemDiv3_014898 COc1ccc(CNc2ccccn2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F05 compound treatment 0.296 0.0704 1.01 0.259 0.0422 0.71 1.2126 0.9853 1464156 ChemDiv3_014899 CCN(CC)CC(O)Cn1ccc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F06 compound treatment 0.244 0.0184 0.26 0.268 0.0512 0.86 0.7935 0.8828 3041049 ChemDiv3_014900 C(Sc1nc2ccccc2[nH]1)c3cc(no3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F07 compound treatment 0.285 0.0594 0.85 0.292 0.0752 1.26 1.493 0.9814 3123755 ChemDiv3_014901 CCc1ccccc1NC(=O)CSc2nc3cccnc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F08 compound treatment 0.3 0.0744 1.06 0.276 0.0592 0.99 1.4549 0.9994 3123756 ChemDiv3_014902 Oc1cccc(NC(=O)C2CC(=NO2)c3cccc(Br)c3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F09 compound treatment 0.321 0.0954 1.36 0.236 0.0192 0.32 1.1925 0.8509 3041050 ChemDiv3_014903 COc1ccc(Cc2nc(c(NCc3ccccc3)o2)S(=O)(=O)c4ccc(C)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F10 compound treatment 0.31 0.0844 1.21 0.283 0.0662 1.11 1.6391 0.9992 3123757 ChemDiv3_014904 COc1ccc(cc1OC)C2CC(n3ncc(C(=O)NCC4CCCO4)c3N2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F11 compound treatment 0.297 0.0714 1.02 0.271 0.0542 0.91 1.3652 0.9984 3041051 ChemDiv3_014905 O=C(Nc1ccccc1)C2CC(=O)N=C(N2)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F12 compound treatment 0.298 0.0724 1.03 0.255 0.0382 0.64 1.1854 0.9735 3123758 ChemDiv3_014906 COc1ccc(cc1)C2CC(=O)c3cnc(Nc4ccccc4OC)nc3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F13 compound treatment 0.275 0.0494 0.71 0.214 -0.00278 -0.05 0.4662 0.6589 3041107 ChemDiv3_014907 CC1=CC(C)(C)N(C(=O)c2ccc(F)cc2)c3cc4OCOc4cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F14 compound treatment 0.232 0.00635 0.09 0.22 0.00322 0.05 0.1025 0.9691 3041108 ChemDiv3_014908 Cc1ccc2[nH]c(NCc3ccccc3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F15 compound treatment 0.299 0.0734 1.05 0.25 0.0332 0.56 1.1362 0.9562 3041109 ChemDiv3_014909 Fc1ccc(CNCc2ccccn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F16 compound treatment 0.246 0.0204 0.29 0.231 0.0142 0.24 0.3746 0.9951 3041110 ChemDiv3_014910 Fc1ccc(CNC(=O)C2CC(=O)NC3=C2C(=O)CCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F17 compound treatment 0.305 0.0794 1.14 0.242 0.0252 0.42 1.1019 0.9096 3041111 ChemDiv3_014911 C(Nc1ccc2n(cnc2c1)c3ccccc3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F18 compound treatment 0.129 -0.0966 -1.38 0.181 -0.0358 -0.6 -1.4021 -0.9303 3041112 ChemDiv3_014912 Cc1[nH]c2ccccc2c1C3(O)C(=O)N(CCc4ccccc4)c5ccc(Br)cc53 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F19 compound treatment 0.315 0.0894 1.28 0.296 0.0792 1.33 1.8439 0.9998 3041113 ChemDiv3_014913 CCn1cnc2cc(NC(=O)c3cc(OC)c(OC)c(OC)c3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F20 compound treatment 0.259 0.0334 0.48 0.177 -0.0398 -0.67 -0.1348 -0.1642 3041114 ChemDiv3_014914 NC(=O)CS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F21 compound treatment 0.286 0.0604 0.86 0.24 0.0232 0.39 0.886 0.9354 3123759 ChemDiv3_014915 CCOC(=O)c1ccc(OCc2nc(no2)c3ccc(OC)c(OC)c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F22 compound treatment 0.228 0.00235 0.03 0.226 0.00922 0.15 0.1332 0.8413 3123760 ChemDiv3_014916 CN1CCC=C(Cc2n[nH]c(=O)c3ccccc23)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F23 mock treatment 0.228 0.00235 0.03 0.236 0.0192 0.32 0.2519 0.7767 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 F24 mock treatment 0.226 3.55E-4 0.01 0.225 0.00822 0.14 0.1011 0.7326 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G01 compound treatment 0.285 0.0594 0.85 0.252 0.0352 0.59 1.0183 0.9843 3041115 ChemDiv3_014917 CCOC(=O)c1cnc(SCC(=O)Nc2ccc(C)cc2Cl)nc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G02 compound treatment 0.197 -0.0286 -0.41 0.252 0.0352 0.59 0.1283 0.1783 1620450 ChemDiv3_014918 Cc1nc2ccccc2c(O)c1CN3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G03 compound treatment 0.259 0.0334 0.48 0.294 0.0772 1.3 1.2538 0.9078 3123761 ChemDiv3_014919 O=S(=O)(NCC1CCCO1)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G04 compound treatment 0.047 -0.179 -2.56 0.056 -0.161 -2.7 -3.715 -0.9996 1718007 ChemDiv3_014920 O=C(CCN1CCC(C1)c2ccccc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G05 compound treatment 0.234 0.00835 0.12 0.222 0.00522 0.09 0.1464 0.9883 3123875 ChemDiv3_014921 O=c1oc2c3CN(COc3ccc2c4CCCc41)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G06 compound treatment 0.283 0.0574 0.82 0.259 0.0422 0.71 1.0812 0.9973 3041116 ChemDiv3_014922 CC1(C)Cc2ccccc2/C(=C/C(=O)Nc3ccccc3)/N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G07 compound treatment 0.299 0.0734 1.05 0.314 0.0972 1.63 1.8957 0.9772 3123876 ChemDiv3_014923 Clc1ccc(cc1)c2cc([nH]n2)C(=O)NC3CCCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G08 compound treatment 0.237 0.0114 0.16 0.287 0.0702 1.18 0.9482 0.797 1412621 ChemDiv3_014924 Fc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G09 compound treatment 0.263 0.0374 0.53 0.275 0.0582 0.98 1.0688 0.9597 3041117 ChemDiv3_014925 CCCCN(C)C(=O)c1cc(n[nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G10 compound treatment 0.286 0.0604 0.86 0.269 0.0522 0.88 1.2302 1.0 3041118 ChemDiv3_014926 CC(=O)Nc1ccc(cc1)c2c[nH]cn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G11 compound treatment 0.28 0.0544 0.78 0.246 0.0292 0.49 0.8965 0.9753 3123877 ChemDiv3_014927 Clc1ccc(COC(=O)CCCC2=NS(=O)(=O)c3ccccc3N2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G12 compound treatment 0.276 0.0504 0.72 0.295 0.0782 1.31 1.4376 0.9601 3041119 ChemDiv3_014928 CCc1c(C)[nH]c2c(C#N)cnn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G13 compound treatment 0.285 0.0594 0.85 0.269 0.0522 0.88 1.2201 0.9999 1528570 ChemDiv3_014929 COc1cc(CCN(C)C)c2ccc3cc(OC)c(OC)cc3c2c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G14 compound treatment 0.257 0.0314 0.45 0.282 0.0652 1.09 1.0912 0.9224 3041120 ChemDiv3_014930 CC(C)(C)NCc1nc(no1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G15 compound treatment 0.288 0.0624 0.89 0.25 0.0332 0.56 1.0249 0.9744 1218570 ChemDiv3_014931 COc1ccc(cc1)C2CNC(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G16 compound treatment 0.284 0.0584 0.83 0.256 0.0392 0.66 1.0557 0.9931 3123878 ChemDiv3_014932 CC1(C)CC(=O)c2cnc(NCCc3ccccc3)nc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G17 compound treatment 0.277 0.0514 0.73 0.275 0.0582 0.98 1.2104 0.9901 3041121 ChemDiv3_014933 O=C(NCCc1nc2ccccc2[nH]1)/C=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G18 compound treatment 0.273 0.0474 0.68 0.222 0.00522 0.09 0.5409 0.792 3123879 ChemDiv3_014934 Cc1cc(C)c(C#N)c(SCCC(=O)Nc2nc(ns2)c3ccccc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G19 compound treatment 0.282 0.0564 0.81 0.251 0.0342 0.57 0.9761 0.9862 1238404 ChemDiv3_014935 CC(=O)Nc1c(nc2cc(C)ccn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G20 compound treatment 0.254 0.0284 0.41 0.185 -0.0318 -0.53 -0.0904 -0.1349 3123880 ChemDiv3_014936 Cn1nc(C(=O)NC2CCCCC2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G21 compound treatment 0.253 0.0274 0.39 0.235 0.0182 0.31 0.4929 0.9926 1458918 ChemDiv3_014937 CC(O)Cn1c(=N)n(C)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G22 compound treatment 0.152 -0.0736 -1.05 0.142 -0.0748 -1.26 -1.6324 -0.9962 3123881 ChemDiv3_014938 OC(=O)C1CCCN(C1)c2c(c3ccccc3)c4cc(Cl)ccc4[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G23 mock treatment 0.195 -0.0306 -0.44 0.221 0.00422 0.07 -0.2599 -0.5853 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 G24 mock treatment 0.201 -0.0246 -0.35 0.196 -0.0208 -0.35 -0.4959 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H01 compound treatment 0.238 0.0124 0.18 0.25 0.0332 0.56 0.5192 0.8877 3041122 ChemDiv3_014939 CCOC(=O)c1cccc(Nc2nc(C)cc(C)n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H02 compound treatment 0.231 0.00535 0.08 0.229 0.0122 0.21 0.1992 0.9098 3123882 ChemDiv3_014940 CC1CC(=O)c2cnc(nc2C1)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H03 compound treatment 0.228 0.00235 0.03 0.237 0.0202 0.34 0.2638 0.7735 3041123 ChemDiv3_014941 Oc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H04 compound treatment 0.273 0.0474 0.68 0.275 0.0582 0.98 1.1699 0.984 3123883 ChemDiv3_014942 CC1(C)CN=C(NCc2cccnc2)S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H05 compound treatment 0.326 0.1 1.44 0.281 0.0642 1.08 1.7772 0.99 3123884 ChemDiv3_014943 COc1ccc(cc1)C2=NNC(=O)c3ccccc3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H06 compound treatment 0.322 0.0964 1.38 0.228 0.0112 0.19 1.1077 0.7963 3041124 ChemDiv3_014944 Cc1cn(CCC(=O)O)c(=O)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H07 compound treatment 0.285 0.0594 0.85 0.242 0.0252 0.42 0.8996 0.9483 3123885 ChemDiv3_014945 CS(=O)(=O)N1CC(=O)Nc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H08 compound treatment 0.309 0.0834 1.19 0.297 0.0802 1.35 1.7951 0.9982 3041125 ChemDiv3_014946 COC(=O)c1ccccc1NC(=O)C2CC(=NO2)c3cccc(Br)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H09 compound treatment 0.331 0.105 1.51 0.281 0.0642 1.08 1.8277 0.9865 3123886 ChemDiv3_014947 O=S(=O)(c1nc(oc1NCc2ccccc2)c3cccs3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H10 compound treatment 0.297 0.0714 1.02 0.303 0.0862 1.45 1.745 0.9854 3123887 ChemDiv3_014948 O=C(Nc1ccc(cc1)N2C(=O)c3cccnc3C2=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H11 compound treatment 0.311 0.0854 1.22 0.254 0.0372 0.62 1.305 0.9516 3041126 ChemDiv3_014949 CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CN4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H12 compound treatment 0.293 0.0674 0.96 0.314 0.0972 1.63 1.835 0.9684 3123888 ChemDiv3_014950 O=C1CC(CC2=C1C=Nc3ccccc3N2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H13 compound treatment 0.297 0.0714 1.02 0.292 0.0752 1.26 1.6144 0.9944 3123889 ChemDiv3_014951 CCCN1C(=O)C(O)(CC(=O)c2ccc(OC)cc2OC)c3cc(Br)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H14 compound treatment 0.264 0.0384 0.55 0.223 0.00622 0.1 0.4617 0.8268 3041127 ChemDiv3_014952 COc1ccc2[nH]c(NCc3ccccc3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H15 compound treatment 0.297 0.0714 1.02 0.302 0.0852 1.43 1.7331 0.9863 3123890 ChemDiv3_014953 Cc1cc(C)cc(c1)N2C(=O)CC(C2=O)n3ccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H16 compound treatment 0.309 0.0834 1.19 0.294 0.0772 1.3 1.7595 0.9991 3041128 ChemDiv3_014954 CCN(CC)C(=O)c1csc(Nc2ccc(OC)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H17 compound treatment 0.302 0.0764 1.09 0.302 0.0852 1.43 1.7837 0.9911 3123891 ChemDiv3_014955 Cn1c(CN2CCOCC2)nc3cc(NS(=O)(=O)c4ccc(F)cc4)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H18 compound treatment 0.288 0.0624 0.89 0.282 0.0652 1.09 1.4047 0.9948 3041129 ChemDiv3_014956 OC(=O)c1cc(NCc2ccccc2)ccc1N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H19 compound treatment 0.243 0.0174 0.25 0.227 0.0102 0.17 0.2968 0.9837 3123892 ChemDiv3_014957 COc1ccc(cc1)n2cnc3cc(NC(=O)c4cccs4)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H20 compound treatment 0.293 0.0674 0.96 0.288 0.0712 1.2 1.5265 0.9943 3041130 ChemDiv3_014958 Cc1cc(c2noc(n2)c3ccccc3C)c4ccccc4n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H21 compound treatment 0.302 0.0764 1.09 0.273 0.0562 0.94 1.4395 0.9973 3123893 ChemDiv3_014959 OC1=CONN1c2cccc3ncccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H22 compound treatment 0.262 0.0364 0.52 0.233 0.0162 0.27 0.5602 0.9544 3123894 ChemDiv3_014960 COc1ccc(CNC(=O)c2cn(C)c(=O)c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H23 mock treatment 0.237 0.0114 0.16 0.216 -7.81E-4 -0.01 0.1056 0.6479 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 H24 mock treatment 0.226 3.55E-4 0.01 0.199 -0.0178 -0.3 -0.2074 -0.695 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I01 compound treatment 0.262 0.0364 0.52 0.228 0.0112 0.19 0.5008 0.9056 3041131 ChemDiv3_014961 Cc1ccc2n(C)c3c(=O)n(c4ccccc4)c(=O)n(CC(=O)c5ccccc5)c3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I02 compound treatment 0.246 0.0204 0.29 0.211 -0.00578 -0.1 0.1373 0.4473 3123895 ChemDiv3_014962 Cc1cc(C)nc(NC(=N)NCc2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I03 compound treatment 0.243 0.0174 0.25 0.227 0.0102 0.17 0.2968 0.9837 3123896 ChemDiv3_014963 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I04 compound treatment 0.257 0.0314 0.45 0.271 0.0542 0.91 0.9606 0.9469 3041132 ChemDiv3_014964 CC1(CNC(=O)C1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I05 compound treatment 0.294 0.0684 0.98 0.271 0.0542 0.91 1.3348 0.9994 3123897 ChemDiv3_014965 CCOC(=O)C1=C(CN2CC(C)CC(C)C2)NC(=O)NC1c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I06 compound treatment 0.283 0.0574 0.82 0.239 0.0222 0.37 0.8438 0.9363 3041133 ChemDiv3_014966 CC1CCN(CC1)C(=N)Nc2nc(C)cc(C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I07 compound treatment 0.309 0.0834 1.19 0.322 0.105 1.77 2.0918 0.9817 3123898 ChemDiv3_014967 Cc1ccsc1CCNC(=O)c2cc(n[nH]2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I08 compound treatment 0.307 0.0814 1.16 0.288 0.0712 1.2 1.6681 0.9999 1144393 ChemDiv3_014968 Fc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I09 compound treatment 0.308 0.0824 1.18 0.294 0.0772 1.3 1.7494 0.9989 3123899 ChemDiv3_014969 O=C(NCc1ccccc1)c2cc(n[nH]2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I10 compound treatment 0.217 -0.00865 -0.12 0.205 -0.0118 -0.2 -0.2273 -0.9745 3123900 ChemDiv3_014970 COc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I11 compound treatment 0.236 0.0104 0.15 0.284 0.0672 1.13 0.9025 0.7931 3041134 ChemDiv3_014971 Cc1ccccc1COC(=O)CCCC2=NS(=O)(=O)c3ccccc3N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I12 compound treatment 0.277 0.0514 0.73 0.208 -0.00878 -0.15 0.4152 0.5542 3123901 ChemDiv3_014972 CN(C1CCCCC1)C(=N)Nc2nc(C)cc(C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I13 compound treatment 0.242 0.0164 0.23 0.261 0.0442 0.74 0.6902 0.887 1922882 ChemDiv3_014973 Cc1ccc(O)c(c1)C2=Nc3ccccc3C2(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I14 compound treatment 0.334 0.108 1.55 0.281 0.0642 1.08 1.8581 0.9842 3041136 ChemDiv3_014974 COc1ccc(NCc2nc(no2)c3ccccc3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I15 compound treatment 0.299 0.0734 1.05 0.259 0.0422 0.71 1.243 0.9817 1555304 ChemDiv3_014975 CNC(=O)Nc1cc(no1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I16 compound treatment 0.313 0.0874 1.25 0.288 0.0712 1.2 1.7288 0.9998 3041137 ChemDiv3_014976 COc1ccc2c(C)nc(O)cc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I17 compound treatment 0.315 0.0894 1.28 0.284 0.0672 1.13 1.7015 0.9981 1919870 ChemDiv3_014977 CNC(=O)NC1CCCCc2sccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I18 compound treatment 0.253 0.0274 0.39 0.284 0.0672 1.13 1.0744 0.8998 3124156 ChemDiv3_014978 Cn1cc(C2CC(=O)N(C2=O)c3ccc(O)cc3)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I19 compound treatment 0.285 0.0594 0.85 0.272 0.0552 0.93 1.2557 0.999 1511504 ChemDiv3_014979 O=C1CCCc2nc(sc12)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I20 compound treatment 0.265 0.0394 0.56 0.259 0.0422 0.71 0.8991 0.9935 3040062 ChemDiv3_014980 COc1cccc(c1)C2N(CCCN(C)C)C(=O)c3oc4ccc(C)cc4c(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I21 compound treatment 0.222 -0.00365 -0.05 0.232 0.0152 0.26 0.1437 0.5514 1483465 ChemDiv3_014981 CCc1ccc(cc1)C(=O)Cn2c(NCCO)nc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I22 compound treatment 0.274 0.0484 0.69 0.225 0.00822 0.14 0.5866 0.8318 3040063 ChemDiv3_014982 Cc1cc(C)n(n1)c2nc(nc3CC(C)(C)OCc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I23 mock treatment 0.217 -0.00865 -0.12 0.172 -0.0448 -0.75 -0.6189 -0.8125 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 I24 mock treatment 0.233 0.00735 0.11 0.185 -0.0318 -0.53 -0.3028 -0.5569 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J01 compound treatment 0.264 0.0384 0.55 0.261 0.0442 0.74 0.9127 0.9889 3040065 ChemDiv3_014983 CC(C)COC(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J02 compound treatment 0.241 0.0154 0.22 0.273 0.0562 0.94 0.8225 0.849 3040067 ChemDiv3_014984 CC1CC(=O)c2c(C)nc(NCc3ccco3)nc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J03 compound treatment 0.262 0.0364 0.52 0.248 0.0312 0.52 0.7382 1.0 3040068 ChemDiv3_014985 CC1CCN(CC1)S(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J04 compound treatment 0.233 0.00735 0.11 0.266 0.0492 0.83 0.6585 0.7908 3040069 ChemDiv3_014986 COc1oc(nc1C(F)(F)F)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J05 compound treatment 0.259 0.0334 0.48 0.271 0.0542 0.91 0.9808 0.9546 3124016 ChemDiv3_014987 Cc1cc(C)cc(CC2CC(=O)N(CC(=O)O)C2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J06 compound treatment 0.26 0.0344 0.49 0.258 0.0412 0.69 0.8367 0.986 3040071 ChemDiv3_014988 C[C@H]1C(O[C@@H]2C(OC(=O)C)C(=O)OC12)n3ccc(=O)[nH]c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J07 compound treatment 0.259 0.0334 0.48 0.25 0.0332 0.56 0.7316 0.997 3124017 ChemDiv3_014989 Cc1cccc(c1)C(=O)c2c([nH]c(=O)c3ccccc23)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J08 compound treatment 0.292 0.0664 0.95 0.308 0.0912 1.53 1.7537 0.9736 3124018 ChemDiv3_014990 CSc1ccccc1NC(=O)C2CC(=NO2)c3cccc(Br)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J09 compound treatment 0.291 0.0654 0.93 0.297 0.0802 1.35 1.6131 0.9841 3040073 ChemDiv3_014991 Cc1nc2ccccc2n1C/C=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J10 compound treatment 0.332 0.106 1.52 0.314 0.0972 1.63 2.2295 0.9994 3124019 ChemDiv3_014992 COc1cccc2C(CC(=O)c3ccc(F)cc3)C4=C(CC(C)(C)CC4=O)Oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J11 compound treatment 0.272 0.0464 0.66 0.272 0.0552 0.93 1.1242 0.9865 3040075 ChemDiv3_014993 CSc1ccccc1NC2=NS(=O)(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J12 compound treatment 0.33 0.104 1.49 0.284 0.0672 1.13 1.8532 0.9905 3124020 ChemDiv3_014994 CCN1CCN(CC1)c2ncc3C(=O)CC(Cc3n2)c4cc(OC)c(OC)c(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J13 compound treatment 0.294 0.0684 0.98 0.241 0.0242 0.41 0.9788 0.9244 3040077 ChemDiv3_014995 Cn1c(CN2CCOCC2)nnc1SCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J14 compound treatment 0.305 0.0794 1.14 0.273 0.0562 0.94 1.4698 0.9958 3124021 ChemDiv3_014996 FC(F)(F)c1nc2[nH]c(cc(=O)n2n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J15 compound treatment 0.291 0.0654 0.93 0.292 0.0752 1.26 1.5537 0.9891 3040079 ChemDiv3_014997 Fc1ccccc1N2C(=O)Cn3c2nc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J16 compound treatment 0.223 -0.00265 -0.04 0.229 0.0122 0.21 0.1183 0.5671 3124022 ChemDiv3_014998 Cn1c(cn2cc(nc12)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J17 compound treatment 0.304 0.0784 1.12 0.224 0.00722 0.12 0.8782 0.779 3040081 ChemDiv3_014999 CCn1c(NCc2ccccn2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J18 compound treatment 0.299 0.0734 1.05 0.264 0.0472 0.79 1.3023 0.9904 3124023 ChemDiv3_015000 COc1cc2CCN(C(c3ccccc3)c2cc1OC)C(=O)CSc4nc5ccccc5o4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J19 compound treatment 0.226 3.55E-4 0.01 0.256 0.0392 0.66 0.469 0.7125 3040082 ChemDiv3_015001 COc1ccccc1OCCn2c(N)nc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J20 compound treatment 0.279 0.0534 0.76 0.264 0.0472 0.79 1.1 0.9998 3124024 ChemDiv3_015002 COC(=O)c1ccc(cc1)c2nc(no2)c3cc(C)nc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J21 compound treatment 0.269 0.0434 0.62 0.239 0.0222 0.37 0.7022 0.9704 1874332 ChemDiv3_015003 O=C(Nc1cnc2ccccn2c1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J22 compound treatment 0.281 0.0554 0.79 0.218 0.00122 0.02 0.5743 0.7251 3124025 ChemDiv3_015004 CN(C(=O)c1cn(C)c(=O)c2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J23 mock treatment 0.25 0.0244 0.35 0.218 0.00122 0.02 0.2608 0.7473 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 J24 mock treatment 0.185 -0.0406 -0.58 0.195 -0.0218 -0.37 -0.6696 -0.975 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K01 compound treatment 0.238 0.0124 0.18 0.207 -0.00978 -0.16 0.0089 0.0368 3124026 ChemDiv3_015005 Fc1ccccc1N/C=C/2\C(=O)c3ccccc3N(Cc4ccc(Cl)cc4)S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K02 compound treatment 0.228 0.00235 0.03 0.246 0.0292 0.49 0.3706 0.7539 1232514 ChemDiv3_015006 CC(C)CC(=O)CC1(O)C(=O)Nc2ccccc21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K03 compound treatment 0.234 0.00835 0.12 0.254 0.0372 0.62 0.5262 0.8274 3124027 ChemDiv3_015007 CSc1cccc(NS(=O)(=O)c2ccc(cc2)n3cccn3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K04 compound treatment 0.261 0.0354 0.51 0.311 0.0942 1.58 1.4758 0.8889 3040086 ChemDiv3_015008 O=C1CC(=Nc2ccccc2N1)/C=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K05 compound treatment 0.219 -0.00665 -0.1 0.245 0.0282 0.47 0.2677 0.5542 3124028 ChemDiv3_015009 CCOC(=O)C1=C(CN(C)c2ccccc2)NC(=O)NC1c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K06 compound treatment 0.286 0.0604 0.86 0.232 0.0152 0.26 0.7911 0.8787 3040088 ChemDiv3_015010 CN(C)CCCNc1c2CCCc2nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K07 compound treatment 0.297 0.0714 1.02 0.268 0.0512 0.86 1.3296 0.9964 3040152 ChemDiv3_015011 COc1ccc(C)cc1NC(=O)c2cc(n[nH]2)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K08 compound treatment 0.295 0.0694 0.99 0.296 0.0792 1.33 1.6416 0.9896 1461241 ChemDiv3_015012 CCN(C(=O)C1Cc2ccccc2CN1S(=O)(=O)c3ccc(F)cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K09 compound treatment 0.296 0.0704 1.01 0.217 2.19E-4 0.0 0.7142 0.7097 3040154 ChemDiv3_015013 CCN(CC)C(=O)c1cc(n[nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K10 compound treatment 0.298 0.0724 1.03 0.277 0.0602 1.01 1.4465 0.9999 3040155 ChemDiv3_015014 Cc1cc(C)nc(NC2=NCCN2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K11 compound treatment 0.3 0.0744 1.06 0.27 0.0532 0.89 1.3836 0.9962 3040157 ChemDiv3_015015 Cc1ccccc1C2Nc3ccccc3S(=O)(=O)N2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K12 compound treatment 0.274 0.0484 0.69 0.234 0.0172 0.29 0.6934 0.9251 1663841 ChemDiv3_015016 CCOC(=O)c1cnc2ccc(cc2c1NCCN(C)C)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K13 compound treatment 0.286 0.0604 0.86 0.247 0.0302 0.51 0.9691 0.9679 1496276 ChemDiv3_015017 O=C1N(CCC2=NCCc3ccccc23)C(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K14 compound treatment 0.295 0.0694 0.99 0.301 0.0842 1.41 1.701 0.985 3040159 ChemDiv3_015018 NC(=O)CCn1nc(c2ccccc2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K15 compound treatment 0.274 0.0484 0.69 0.282 0.0652 1.09 1.2631 0.9755 3040160 ChemDiv3_015019 COCc1cc(C)[nH]c(=O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K16 compound treatment 0.257 0.0314 0.45 0.269 0.0522 0.88 0.9369 0.9516 3124029 ChemDiv3_015020 Cc1n[nH]c2NC(=O)CC(c12)c3ccc4ccccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K17 compound treatment 0.291 0.0654 0.93 0.215 -0.00178 -0.03 0.6399 0.6841 3040162 ChemDiv3_015021 CCC1(CC)Cc2ccccc2C(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K18 compound treatment 0.286 0.0604 0.86 0.278 0.0612 1.03 1.337 0.9963 1313313 ChemDiv3_015022 Cc1nc(C)c2c(=O)cc([nH]c2n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K19 compound treatment 0.24 0.0144 0.21 0.231 0.0142 0.24 0.3139 0.9972 1189980 ChemDiv3_015023 Fc1ccc(Cc2nc3ccccc3[nH]2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K20 compound treatment 0.273 0.0474 0.68 0.227 0.0102 0.17 0.6002 0.859 3124030 ChemDiv3_015024 COC(=O)c1ccc(cc1)C2N(CCCN(C)C)C(=O)c3oc4ccc(F)cc4c(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K21 compound treatment 0.239 0.0134 0.19 0.24 0.0232 0.39 0.4106 0.9462 1271487 ChemDiv3_015025 CCCCn1c(=N)n(CC(=O)OC)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K22 compound treatment 0.258 0.0324 0.46 0.241 0.0242 0.41 0.6147 0.9979 3124031 ChemDiv3_015026 COc1ccc(cc1)C2(CNC(=O)CCC(=O)O)CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K23 mock treatment 0.189 -0.0366 -0.52 0.241 0.0242 0.41 -0.0832 -0.1254 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 K24 mock treatment 0.195 -0.0306 -0.44 0.238 0.0212 0.36 -0.0581 -0.1029 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L01 compound treatment 0.237 0.0114 0.16 0.227 0.0102 0.17 0.2361 0.9996 3040165 ChemDiv3_015027 Cc1cc(C)nc(NCCCN2CCOCC2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L02 compound treatment 0.236 0.0104 0.15 0.225 0.00822 0.14 0.2023 0.9994 3124032 ChemDiv3_015028 Clc1ccc(SCc2cc(=O)c3c(=O)n([nH]c3[nH]2)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L03 compound treatment 0.247 0.0214 0.31 0.241 0.0242 0.41 0.5034 0.9901 3040167 ChemDiv3_015029 Cn1c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L04 compound treatment 0.251 0.0254 0.36 0.251 0.0342 0.57 0.6626 0.9754 3124033 ChemDiv3_015030 OC(=O)c1ccc(NCc2cccnc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L05 compound treatment 0.244 0.0184 0.26 0.28 0.0632 1.06 0.9359 0.8562 3124034 ChemDiv3_015031 Fc1cnc(nc1N2CCc3ccccc23)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L06 compound treatment 0.293 0.0674 0.96 0.28 0.0632 1.06 1.4315 0.9988 3040169 ChemDiv3_015032 Clc1ccc(Cn2ccc(nc2=O)N3CCOCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L07 compound treatment 0.267 0.0414 0.59 0.256 0.0392 0.66 0.8837 0.9986 3124035 ChemDiv3_015033 COc1ccc(NC(c2ccccn2)c3oc(CO)cc(=O)c3O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L08 compound treatment 0.311 0.0854 1.22 0.265 0.0482 0.81 1.4356 0.9801 3040171 ChemDiv3_015034 Cc1cc(NC(=O)C2CC(=NO2)c3ccc(Cl)cc3)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L09 compound treatment 0.292 0.0664 0.95 0.216 -7.81E-4 -0.01 0.6619 0.6973 3124036 ChemDiv3_015035 Fc1ccc(cc1)C(=O)NCCCc2nc3ccccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L10 compound treatment 0.313 0.0874 1.25 0.287 0.0702 1.18 1.7169 0.9996 3040173 ChemDiv3_015036 N1N=C(c2ccncc2)c3ccccc3N=C1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L11 compound treatment 0.302 0.0764 1.09 0.265 0.0482 0.81 1.3445 0.9891 3124037 ChemDiv3_015037 O=C(CC1Nc2cccc3cccc(NC1=O)c23)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L12 compound treatment 0.285 0.0594 0.85 0.314 0.0972 1.63 1.7541 0.9537 3124038 ChemDiv3_015038 Cc1nc2[nH]c(CSc3ccc(Cl)cc3)cc(=O)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L13 compound treatment 0.278 0.0524 0.75 0.257 0.0402 0.68 1.0068 0.9987 1308709 ChemDiv3_015039 Cc1nc(c(CC(=O)O)s1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L14 compound treatment 0.311 0.0854 1.22 0.272 0.0552 0.93 1.5186 0.9908 3124039 ChemDiv3_015040 COc1ccc(cc1)C2CC(=O)c3cnn(c4nc5ccccc5s4)c3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L15 compound treatment 0.302 0.0764 1.09 0.287 0.0702 1.18 1.6056 0.9993 3040237 ChemDiv3_015041 COc1cc(CO)ccc1Oc2nnnn2c3ccc(cc3)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L16 compound treatment 0.268 0.0424 0.61 0.294 0.0772 1.3 1.3448 0.94 3040238 ChemDiv3_015042 Cn1c(cn2cc(nc12)c3ccc(Br)cc3)c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L17 compound treatment 0.285 0.0594 0.85 0.219 0.00222 0.04 0.6267 0.7374 3040240 ChemDiv3_015043 CCCCn1c(NCc2ccccn2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L18 compound treatment 0.242 0.0164 0.23 0.078 -0.139 -2.33 -1.4817 -0.6329 1524459 ChemDiv3_015044 OC(=O)CSCC(=O)N1CCn2c3C1CCCc3c4cc(ccc24)C5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L19 compound treatment 0.279 0.0534 0.76 0.284 0.0672 1.13 1.3374 0.9819 3040242 ChemDiv3_015045 COc1ccccc1OCCn2c(CO)nc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L20 compound treatment 0.282 0.0564 0.81 0.272 0.0552 0.93 1.2253 0.9976 3040243 ChemDiv3_015046 CCc1nc(c(C#N)cc1C)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L21 compound treatment 0.267 0.0414 0.59 0.276 0.0592 0.99 1.1211 0.9693 3040245 ChemDiv3_015047 Cc1sc2nc(SCc3nc(no3)c4cccs4)n(c5ccccc5)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L22 compound treatment 0.291 0.0654 0.93 0.259 0.0422 0.71 1.1621 0.9907 3124040 ChemDiv3_015048 CCOC(=O)c1cn(C)c(=O)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L23 mock treatment 0.241 0.0154 0.22 0.229 0.0122 0.21 0.3003 0.9994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 L24 mock treatment 0.233 0.00735 0.11 0.231 0.0142 0.24 0.2431 0.9323 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M01 compound treatment 0.295 0.0694 0.99 0.26 0.0432 0.73 1.2144 0.9882 3124041 ChemDiv3_015049 Clc1ccc(CN2c3ccccc3C(=O)/C(=C\NCc4ccccc4)/S2(=O)=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M02 compound treatment 0.3 0.0744 1.06 0.269 0.0522 0.88 1.3718 0.9954 1486647 ChemDiv3_015050 Cn1c(Cn2cnc3ccccc23)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M03 compound treatment 0.277 0.0514 0.73 0.261 0.0442 0.74 1.0442 1.0 3124042 ChemDiv3_015051 CC(C)c1ccc(NS(=O)(=O)c2ccc(cc2)n3cccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M04 compound treatment 0.27 0.0444 0.63 0.267 0.0502 0.84 1.0446 0.9902 1054354 ChemDiv3_015052 Cc1cc(O)nc(n1)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M05 compound treatment 0.267 0.0414 0.59 0.269 0.0522 0.88 1.038 0.9817 3040248 ChemDiv3_015053 CCOC(=O)c1cc(C)n(CC2CCC(CC2)C(=O)N3CCCC3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M06 compound treatment 0.28 0.0544 0.78 0.297 0.0802 1.35 1.5018 0.9659 3124043 ChemDiv3_015054 CCC(=O)NC(C)Cc1c[nH]c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M07 compound treatment 0.266 0.0404 0.58 0.252 0.0352 0.59 0.8261 0.9999 3124044 ChemDiv3_015055 CCOc1ccc(cc1)c2cc([nH]n2)C(=O)NC(C)c3ccc4OCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M08 compound treatment 0.316 0.0904 1.29 0.313 0.0962 1.61 2.0558 0.9939 1604600 ChemDiv3_015056 Fc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M09 compound treatment 0.307 0.0814 1.16 0.274 0.0572 0.96 1.5019 0.9955 3124157 ChemDiv3_015057 Cc1ccnc(NC(=O)c2cc(n[nH]2)c3ccc(C)c(C)c3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M10 compound treatment 0.306 0.0804 1.15 0.214 -0.00278 -0.05 0.7797 0.6778 1188380 ChemDiv3_015058 NC(=O)COc1cccc2cccnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M11 compound treatment 0.169 -0.0566 -0.81 0.176 -0.0408 -0.68 -1.0569 -0.9965 3124158 ChemDiv3_015059 Cc1cccc(C)c1Nc2nn3c(=O)c4ccccc4nc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M12 compound treatment 0.283 0.0574 0.82 0.256 0.0392 0.66 1.0456 0.994 3040251 ChemDiv3_015060 CN1CCc2c(C1=O)n(CC(O)CN3CCCC3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M13 compound treatment 0.273 0.0474 0.68 0.236 0.0192 0.32 0.707 0.9424 1660192 ChemDiv3_015061 Oc1cccc(c1)C2CC(=O)c3c(N2)ccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M14 compound treatment 0.3 0.0744 1.06 0.262 0.0452 0.76 1.2887 0.9863 1347735 ChemDiv3_015062 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCCCC2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M15 compound treatment 0.293 0.0674 0.96 0.231 0.0142 0.24 0.85 0.8564 1103139 ChemDiv3_015063 Cc1ccc(cc1)c2cn3CCSc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M16 compound treatment 0.111 -0.115 -1.64 0.111 -0.106 -1.78 -2.415 -0.9992 3124159 ChemDiv3_015064 CC(Nc1nc2ccccc2n1CC=C)c3cc(Cl)ccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M17 compound treatment 0.284 0.0584 0.83 0.255 0.0382 0.64 1.0438 0.9915 1357733 ChemDiv3_015065 CCOc1ccc2[nH]c(NCCO)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M18 compound treatment 0.263 0.0374 0.53 0.248 0.0312 0.52 0.7483 1.0 3040255 ChemDiv3_015066 CCN(c1ccccc1)c2cc(=O)n(C)c(=O)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M19 compound treatment 0.274 0.0484 0.69 0.245 0.0282 0.47 0.824 0.9829 3040193 ChemDiv3_015067 Cc1ccc(cc1)c2cc(on2)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M20 compound treatment 0.071 -0.155 -2.21 0.058 -0.159 -2.66 -3.4485 -0.9957 3040107 ChemDiv3_015068 CCN1CCOC(CC(=O)Nc2cccc(OC)c2)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M21 compound treatment 0.253 0.0274 0.39 0.246 0.0292 0.49 0.6234 0.9937 1581966 ChemDiv3_015069 Cc1ccc2[nH]c(NCCO)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M22 compound treatment 0.235 0.00935 0.13 0.2 -0.0168 -0.28 -0.1045 -0.3353 3040109 ChemDiv3_015070 O=c1[nH][nH]c(=O)c2c(NS(=O)(=O)c3ccccc3)cccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M23 mock treatment 0.247 0.0214 0.31 0.214 -0.00278 -0.05 0.183 0.5922 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 M24 mock treatment 0.208 -0.0176 -0.25 0.223 0.00622 0.1 -0.1047 -0.3832 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N01 compound treatment 0.265 0.0394 0.56 0.294 0.0772 1.3 1.3145 0.9303 3040112 ChemDiv3_015071 Cc1cc(C)nc(Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N02 compound treatment 0.267 0.0414 0.59 0.248 0.0312 0.52 0.7888 0.9982 3040113 ChemDiv3_015072 O=c1n([nH]c2[nH]c(CSc3nnnn3c4ccccc4)cc(=O)c12)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N03 compound treatment 0.246 0.0204 0.29 0.222 0.00522 0.09 0.2678 0.8808 3040114 ChemDiv3_015073 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N(C(=O)c4ccncc4)c5ccc(OC)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N04 compound treatment 0.272 0.0464 0.66 0.299 0.0822 1.38 1.4446 0.9436 3040117 ChemDiv3_015074 Cc1cc(on1)c2ccccc2C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N05 compound treatment 0.304 0.0784 1.12 0.242 0.0252 0.42 1.0918 0.9113 1284849 ChemDiv3_015075 O=C1CC(C(=O)N1c2ccccc2)c3c[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N06 compound treatment 0.278 0.0524 0.75 0.272 0.0552 0.93 1.1849 0.9944 3124160 ChemDiv3_015076 O=C(NCCCn1ccnc1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N07 compound treatment 0.299 0.0734 1.05 0.248 0.0312 0.52 1.1124 0.9485 3040120 ChemDiv3_015077 CC(C)CC(Nc1ncnc2c3ccccc3oc12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N08 compound treatment 0.295 0.0694 0.99 0.273 0.0562 0.94 1.3687 0.9997 3124161 ChemDiv3_015078 Clc1ccc(cc1)C2=NOC(C2)C(=O)N3CCN(CC3)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N09 compound treatment 0.143 -0.0826 -1.18 0.17 -0.0468 -0.79 -1.3911 -0.9802 3040123 ChemDiv3_015079 CCOC(=O)c1c(Cc2cccc(C)c2)c[nH]c1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N10 compound treatment 0.327 0.101 1.45 0.281 0.0642 1.08 1.7873 0.9893 3124162 ChemDiv3_015080 CCc1c(C)nc2SCC(CS(=O)(=O)c3ccc(C)cc3)n2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N11 compound treatment 0.311 0.0854 1.22 0.284 0.0672 1.13 1.6611 0.9992 3040127 ChemDiv3_015081 CCN(CC)C(=O)Cn1c(nc2ccccc12)S(=O)(=O)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N12 compound treatment 0.266 0.0404 0.58 0.276 0.0592 0.99 1.111 0.9666 3124163 ChemDiv3_015082 CC1=NN(C(=O)C1Cc2ccccc2)c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N13 compound treatment 0.297 0.0714 1.02 0.299 0.0822 1.38 1.6975 0.989 3040195 ChemDiv3_015083 CCn1c(SCC(=O)N2CCCCC2)nnc1c3ccccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N14 compound treatment 0.268 0.0424 0.61 0.246 0.0292 0.49 0.7752 0.9945 3040197 ChemDiv3_015084 CC(C)c1ccc(cc1)C2CC(=O)c3cnc4c(c(C)nn4c3C2)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N15 compound treatment 0.203 -0.0226 -0.32 0.171 -0.0458 -0.77 -0.7724 -0.9262 3040198 ChemDiv3_015085 O(c1nnnn1c2ccccc2)c3cccc4cccnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N16 compound treatment 0.045 -0.181 -2.58 0.043 -0.174 -2.92 -3.8895 -0.9982 3040201 ChemDiv3_015086 CCCCn1c(NCc2cccc(Cl)c2)ncc1c3ccc(OCC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N17 compound treatment 0.277 0.0514 0.73 0.26 0.0432 0.73 1.0323 1.0 3040202 ChemDiv3_015087 C(Nc1nc2ccccc2n1Cc3ccccc3)c4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N18 compound treatment 0.276 0.0504 0.72 0.239 0.0222 0.37 0.773 0.953 3040204 ChemDiv3_015088 Cc1n[nH]c(C)c1Nc2nc(cs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N19 compound treatment 0.268 0.0424 0.61 0.263 0.0462 0.78 0.9769 0.9925 3124164 ChemDiv3_015089 CC1CCCC(C)N1CC(O)Cn2cc(/C=N/O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N20 compound treatment 0.28 0.0544 0.78 0.237 0.0202 0.34 0.7897 0.9309 1537967 ChemDiv3_015090 Fc1ccc(c(F)c1)n2cc(C(=O)N3CCN(CC3)c4ccccc4)c5ccccc5c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N21 compound treatment 0.244 0.0184 0.26 0.245 0.0282 0.47 0.5205 0.9613 3124165 ChemDiv3_015091 O=c1cc(nc(SCc2nc(no2)c3cccs3)[nH]1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N22 compound treatment 0.307 0.0814 1.16 0.222 0.00522 0.09 0.8848 0.7582 3040208 ChemDiv3_015092 Cn1cc(C(=O)Nc2cccnc2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N23 mock treatment 0.257 0.0314 0.45 0.228 0.0112 0.19 0.4503 0.9257 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 N24 mock treatment 0.237 0.0114 0.16 0.216 -7.81E-4 -0.01 0.1056 0.6479 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O01 compound treatment 0.274 0.0484 0.69 0.261 0.0442 0.74 1.0139 0.9994 3124166 ChemDiv3_015093 O=S(=O)(NCCC1=CCCCC1)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O02 compound treatment 0.254 0.0284 0.41 0.253 0.0362 0.61 0.7166 0.9807 1235889 ChemDiv3_015094 COc1ccccc1C(=O)c2nc3ccccc3n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O03 compound treatment 0.253 0.0274 0.39 0.261 0.0442 0.74 0.8015 0.9553 3124167 ChemDiv3_015095 CC(CNS(=O)(=O)c1ccc(cc1)n2cccn2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O04 compound treatment 0.294 0.0684 0.98 0.271 0.0542 0.91 1.3348 0.9994 1613440 ChemDiv3_015096 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O05 compound treatment 0.253 0.0274 0.39 0.218 0.00122 0.02 0.2911 0.7431 3124168 ChemDiv3_015097 CCOC(=O)c1cc(C)n(CC2CCC(CC2)C(=O)NCc3ccccc3)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O06 compound treatment 0.265 0.0394 0.56 0.274 0.0572 0.96 1.0771 0.9676 1590447 ChemDiv3_015098 O=C1NCCCC(=C1NCc2ccccc2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O07 compound treatment 0.173 -0.0526 -0.75 0.171 -0.0458 -0.77 -1.0758 -0.9999 3040277 ChemDiv3_015099 O=C(NCCC1=CCCCC1)c2cc(n[nH]2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O08 compound treatment 0.259 0.0334 0.48 0.222 0.00522 0.09 0.3993 0.8232 3040279 ChemDiv3_015100 CC1(C)CC(CC(=O)O)(CCO1)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O09 compound treatment 0.258 0.0324 0.46 0.235 0.0182 0.31 0.5435 0.9798 3040282 ChemDiv3_015101 Cc1ccc(cc1C)c2cc([nH]n2)C(=O)Nc3cccc4CCCCc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O10 compound treatment 0.193 -0.0326 -0.47 0.18 -0.0368 -0.62 -0.7667 -0.9905 3040284 ChemDiv3_015102 CC(C)CC(=O)/C=C\1/Nc2cc(C)ccc2OC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O11 compound treatment 0.271 0.0454 0.65 0.259 0.0422 0.71 0.9598 0.999 3040285 ChemDiv3_015103 COC(=O)c1ccc(CSc2ccc(Br)cc2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O12 compound treatment 0.248 0.0224 0.32 0.239 0.0222 0.37 0.4898 0.9971 3040287 ChemDiv3_015104 CCn1c2C(=O)CCCc2c3ccc(OC)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O13 compound treatment 0.231 0.00535 0.08 0.213 -0.00378 -0.06 0.0093 0.0933 1486519 ChemDiv3_015105 CCn1cc(C(=O)N(Cc2ccco2)Cc3ccc(cc3)N(C)C)c(=O)c4ccc(C)nc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O14 compound treatment 0.262 0.0364 0.52 0.234 0.0172 0.29 0.5721 0.9616 3124169 ChemDiv3_015106 CC1CN/C(=C/C(=O)c2ccccc2)/C(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O15 compound treatment 0.185 -0.0406 -0.58 0.14 -0.0768 -1.29 -1.3223 -0.9353 1708643 ChemDiv3_015107 Nc1ccc(cc1)C(=O)Nc2nc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O16 compound treatment 0.232 0.00635 0.09 0.212 -0.00478 -0.08 0.0075 0.0621 3124170 ChemDiv3_015108 Cc1ccnc(NCc2ccc(Br)cc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O17 compound treatment 0.25 0.0244 0.35 0.238 0.0212 0.36 0.4982 0.9999 3040293 ChemDiv3_015109 CCCN1C2=NCCCN2c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O18 compound treatment 0.228 0.00235 0.03 0.197 -0.0198 -0.33 -0.2109 -0.6321 3124171 ChemDiv3_015110 COC(=O)CC1=Nc2ccccc2NC(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O19 compound treatment 0.232 0.00635 0.09 0.208 -0.00878 -0.15 -0.0399 -0.2307 1783629 ChemDiv3_015111 COc1cc2cc(C)nc(C)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O20 compound treatment 0.043 -0.183 -2.61 0.042 -0.175 -2.93 -3.9216 -0.9983 3124172 ChemDiv3_015112 CCN1CCOC(CC(=O)Nc2ccccc2C)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O21 compound treatment 0.253 0.0274 0.39 0.219 0.00222 0.04 0.303 0.7709 1254074 ChemDiv3_015113 Cc1nc2ccccc2n1CCOc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O22 compound treatment 0.221 -0.00465 -0.07 0.203 -0.0138 -0.23 -0.2105 -0.8748 3040803 ChemDiv3_015114 CCN(CC)c1ccc(Nc2nc(cs2)c3cccs3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O23 mock treatment 0.23 0.00435 0.06 0.222 0.00522 0.09 0.106 0.986 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 O24 mock treatment 0.212 -0.0136 -0.2 0.214 -0.00278 -0.05 -0.171 -0.8522 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P01 compound treatment 0.239 0.0134 0.19 0.25 0.0332 0.56 0.5293 0.8981 3040805 ChemDiv3_015115 CN(c1ccccc1C(=O)O)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P02 compound treatment 0.238 0.0124 0.18 0.227 0.0102 0.17 0.2462 0.9999 1874619 ChemDiv3_015116 Cc1cc2NC(=O)CC(=Nc2cc1C)c3ccccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P03 compound treatment 0.257 0.0314 0.45 0.257 0.0402 0.68 0.7944 0.9803 3040809 ChemDiv3_015117 CNc1nc(ncc1F)N2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P04 compound treatment 0.258 0.0324 0.46 0.275 0.0582 0.98 1.0182 0.9417 3040810 ChemDiv3_015118 COc1ccccc1C2=NOC(COc3ccc(Cl)c4cccnc34)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P05 compound treatment 0.28 0.0544 0.78 0.276 0.0592 0.99 1.2526 0.9926 3040813 ChemDiv3_015119 CN1C(=O)CC(C1=O)c2cn(Cc3ccccc3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P06 compound treatment 0.239 0.0134 0.19 0.264 0.0472 0.79 0.6955 0.8531 3124173 ChemDiv3_015120 COc1ccc(cc1)c2cc(n3ncc(C(=O)Nc4cccc(O)c4)c3n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P07 compound treatment 0.257 0.0314 0.45 0.238 0.0212 0.36 0.569 0.9935 3040816 ChemDiv3_015121 OC(=O)C(Cc1ccccc1)Nc2ncnc3c4ccccc4oc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P08 compound treatment 0.224 -0.00165 -0.02 0.274 0.0572 0.96 0.6624 0.6896 3124174 ChemDiv3_015122 O=C(NCCCn1ccnc1)c2cc(on2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P09 compound treatment 0.236 0.0104 0.15 0.242 0.0252 0.42 0.404 0.901 3124175 ChemDiv3_015123 CCc1ccc(NC2=NC(=O)CC(N2)C(=O)Nc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P10 compound treatment 0.239 0.0134 0.19 0.245 0.0282 0.47 0.47 0.9203 3040822 ChemDiv3_015124 Cc1ccc(cc1)S(=O)(=O)CC2CSc3nnc(C)c(=O)n23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P11 compound treatment 0.263 0.0374 0.53 0.253 0.0362 0.61 0.8077 0.9979 3040861 ChemDiv3_015125 CCS(=O)(=O)c1nc2ccccc2n1Cc3ccc(cc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P12 compound treatment 0.299 0.0734 1.05 0.274 0.0572 0.96 1.421 0.999 3040862 ChemDiv3_015126 CC(C)CCC1C(=NN(C1=O)c2nc3ccccc3[nH]2)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P13 compound treatment 0.256 0.0304 0.43 0.229 0.0122 0.21 0.452 0.9414 3040865 ChemDiv3_015127 Clc1ccc(CNC2CN3CCC2CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P14 compound treatment 0.237 0.0114 0.16 0.238 0.0212 0.36 0.3667 0.9368 3040868 ChemDiv3_015128 CCc1c(C)nc([nH]c1=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P15 compound treatment 0.264 0.0384 0.55 0.286 0.0692 1.16 1.2094 0.9413 3040872 ChemDiv3_015129 CCn1c(NCCSc2nc3ccccc3n2C)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P16 compound treatment 0.28 0.0544 0.78 0.234 0.0172 0.29 0.7541 0.9092 3040874 ChemDiv3_015130 Cn1c(NCc2ccccc2)ncc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P17 compound treatment 0.287 0.0614 0.88 0.258 0.0412 0.69 1.1097 0.9931 3040877 ChemDiv3_015131 CCCn1c(Nc2nc3ccccc3n2C)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P18 compound treatment 0.294 0.0684 0.98 0.252 0.0352 0.59 1.1093 0.971 3040880 ChemDiv3_015132 Cc1n[nH]c(C)c1NC(=O)CSc2nc(C)cc(C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P19 compound treatment 0.262 0.0364 0.52 0.27 0.0532 0.89 0.9993 0.9669 3040932 ChemDiv3_015133 Cc1cn2c(nc3ccccc32)n1CCCO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P20 compound treatment 0.242 0.0164 0.23 0.238 0.0212 0.36 0.4172 0.9792 3040936 ChemDiv3_015134 CN(c1ccc(Cl)cc1)c2cc(=O)n(C)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P21 compound treatment 0.247 0.0214 0.31 0.239 0.0222 0.37 0.4797 0.9951 3040938 ChemDiv3_015135 CCOc1ccc(cc1S(=O)(=O)Nc2ccc(Cl)cn2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P22 compound treatment 0.261 0.0354 0.51 0.263 0.0462 0.78 0.9061 0.9785 3040941 ChemDiv3_015136 Cn1cc(NC(=O)NC2CCCCC2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P23 mock treatment 0.267 0.0414 0.59 0.245 0.0282 0.47 0.7532 0.9939 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2043 P24 mock treatment 0.231 0.00535 0.08 0.173 -0.0438 -0.73 -0.4654 -0.63 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A01 compound treatment 0.234 0.0206 0.29 0.2 -0.0103 -0.17 0.0863 0.2533 3040942 ChemDiv3_015137 Cc1cccc(N2CCN(CC2)C(=O)Nc3cn(C)c(=O)c4ccccc34)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A02 compound treatment 0.23 0.0166 0.24 0.212 0.00175 0.03 0.1883 0.7887 3040946 ChemDiv3_015138 COc1cc2NC(=O)CC(c3ccccc3)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A03 compound treatment 0.192 -0.0214 -0.31 0.221 0.0107 0.18 -0.0892 -0.2508 3040947 ChemDiv3_015139 CC(=O)N(c1ccccc1)C2(CCCCC2)C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A04 compound treatment 0.2 -0.0134 -0.19 0.199 -0.0113 -0.19 -0.2694 -1.0 3040949 ChemDiv3_015140 CCc1nc2nc(C)cc(NCCc3ccccc3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A05 compound treatment 0.194 -0.0194 -0.28 0.192 -0.0182 -0.31 -0.4132 -0.9988 3124176 ChemDiv3_015141 COc1ccc(cc1)C2C(C(=O)N3CCCC3)c4cc(OC)c(OC)cc4C(=O)N2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A06 compound treatment 0.223 0.00956 0.14 0.209 -0.00125 -0.02 0.0819 0.5917 3124177 ChemDiv3_015142 COc1cc(Cl)c(C)cc1NCC(O)Cn2nnnc2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A07 compound treatment 0.208 -0.00544 -0.08 0.2 -0.0103 -0.17 -0.1766 -0.9356 3041005 ChemDiv3_015143 CC(=O)Nc1c(nc2ccccn12)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A08 compound treatment 0.223 0.00956 0.14 0.201 -0.00925 -0.16 -0.0131 -0.0631 3041006 ChemDiv3_015144 COc1ccc(NS(=O)(=O)c2c(C)nc3sccn3c2=O)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A09 compound treatment 0.196 -0.0174 -0.25 0.196 -0.0143 -0.24 -0.3455 -0.9998 3041010 ChemDiv3_015145 Cc1c(nnn1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A10 compound treatment 0.193 -0.0204 -0.29 0.217 0.00675 0.11 -0.1266 -0.4038 3041011 ChemDiv3_015146 C(c1nnc(o1)c2ccccc2)c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A11 compound treatment 0.222 0.00856 0.12 0.196 -0.0143 -0.24 -0.0825 -0.3071 3041014 ChemDiv3_015147 CCc1ccc(NC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A12 compound treatment 0.215 0.00156 0.02 0.211 7.5E-4 0.01 0.0247 0.9631 3041016 ChemDiv3_015148 Clc1cccc(NC(=O)c2ncn(n2)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A13 compound treatment 0.194 -0.0194 -0.28 0.179 -0.0313 -0.52 -0.5675 -0.9559 3041019 ChemDiv3_015149 CC(N1C(=O)COc2ccc(C)cc12)C(=O)NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A14 compound treatment 0.186 -0.0274 -0.39 0.186 -0.0243 -0.41 -0.5653 -0.9998 3041021 ChemDiv3_015150 Brc1cccc(c1)c2nnc(CN3CCOCC3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A15 compound treatment 0.199 -0.0144 -0.21 0.219 0.00875 0.15 -0.0422 -0.1664 3124178 ChemDiv3_015151 CC1(CCC(=O)N1Cc2cccnc2)C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A16 compound treatment 0.188 -0.0254 -0.36 0.212 0.00175 0.03 -0.2365 -0.6479 3041025 ChemDiv3_015152 Cc1ccc(CN2CCN(CC(=O)N3CCC4(CC3)OCCO4)C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A17 compound treatment 0.189 -0.0244 -0.35 0.194 -0.0163 -0.27 -0.44 -0.9925 3124179 ChemDiv3_015153 CC(C)CCN1C(C(=O)NCc2cccnc2)c3ccccc3C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A18 compound treatment 0.192 -0.0214 -0.31 0.215 0.00475 0.08 -0.1605 -0.5064 3041087 ChemDiv3_015154 COc1ccc(cc1)N2Cc3cccc(C(=O)N4CCOCC4)c3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A19 compound treatment 0.2 -0.0134 -0.19 0.199 -0.0113 -0.19 -0.2694 -1.0 3041089 ChemDiv3_015155 CCN1CCN(CCNC(=O)Nc2ccccc2C)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A20 compound treatment 0.211 -0.00244 -0.03 0.209 -0.00125 -0.02 -0.0395 -0.9705 3041093 ChemDiv3_015156 CCOC(=O)CCc1c(C)nn2cnnc2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A21 compound treatment 0.202 -0.0114 -0.16 0.193 -0.0173 -0.29 -0.3204 -0.9635 3041096 ChemDiv3_015157 COc1cc(NC(=O)NCC2CCN(Cc3cc(C)ccc3C)CC2)cc(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A22 compound treatment 0.212 -0.00144 -0.02 0.207 -0.00325 -0.05 -0.0531 -0.9111 3041099 ChemDiv3_015158 CCC(C)NC(=O)c1cccc2CN(CC3CCCO3)C(=O)c21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A23 mock treatment 0.194 -0.0194 -0.28 0.207 -0.00325 -0.05 -0.2352 -0.83 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 A24 mock treatment 0.207 -0.00644 -0.09 0.206 -0.00425 -0.07 -0.1155 -0.992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B01 compound treatment 0.235 0.0216 0.31 0.196 -0.0143 -0.24 0.049 0.1255 3041100 ChemDiv3_015159 O=C(Nc1ccc2OCCOc2c1)c3cccc4CN(Cc5cccnc5)C(=O)c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B02 compound treatment 0.198 -0.0154 -0.22 0.232 0.0217 0.37 0.102 0.2391 3124180 ChemDiv3_015160 O=C(Cn1ncc2ccsc2c1=O)NCCN3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B03 compound treatment 0.225 0.0116 0.17 0.2 -0.0103 -0.17 -0.0047 -0.0197 3041104 ChemDiv3_015161 Cc1cc(C)cc(NS(=O)(=O)c2ccc3NC(=O)Cc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B04 compound treatment 0.18 -0.0334 -0.48 0.201 -0.00925 -0.16 -0.448 -0.8909 3124181 ChemDiv3_015162 O=C(CCCn1nc(c2ccccc2)c3ccccc13)N4CCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B05 compound treatment 0.247 0.0336 0.48 0.27 0.0597 1.0 1.0486 0.9431 3124432 ChemDiv3_015163 CC(C)c1ccc(NC(=O)[C@H](N2Cc3ccccc3C2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B06 compound treatment 0.238 0.0246 0.35 0.237 0.0267 0.45 0.5659 0.9926 3041177 ChemDiv3_015164 CC(C)NC(=O)c1cccc2sc(nc12)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B07 compound treatment 0.22 0.00656 0.09 0.209 -0.00125 -0.02 0.0515 0.5358 3041178 ChemDiv3_015165 COc1ccccc1CNC(=O)c2cc(C)c3c(C)nn(c4ccccc4Cl)c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B08 compound treatment 0.199 -0.0144 -0.21 0.191 -0.0193 -0.32 -0.3745 -0.9766 3041182 ChemDiv3_015166 O=C(Cn1ncc2COc3ccccc3-c21)N4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B09 compound treatment 0.221 0.00756 0.11 0.213 0.00275 0.05 0.1091 0.9279 3041185 ChemDiv3_015167 COc1ccc(CN2CC(CC2=O)C(=O)N3CCn4c(C3)nc5ccccc45)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B10 compound treatment 0.218 0.00456 0.07 0.233 0.0227 0.38 0.3161 0.8161 3041188 ChemDiv3_015168 COc1ccc(cc1)N2CCN(CC2)c3nc(no3)c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B11 compound treatment 0.211 -0.00244 -0.03 0.207 -0.00325 -0.05 -0.0632 -0.9766 3041190 ChemDiv3_015169 OC(=O)c1ncccc1C(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B12 compound treatment 0.228 0.0146 0.21 0.228 0.0177 0.3 0.3579 0.9847 3124295 ChemDiv3_015170 COc1ccc(cc1)N2CCN(CCCNC(=O)CN3C(=O)CCSc4ccccc34)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B13 compound treatment 0.214 5.62E-4 0.01 0.199 -0.0113 -0.19 -0.1278 -0.6764 3041193 ChemDiv3_015171 Cc1cccc(c1)c2nnc(o2)C3CCNCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B14 compound treatment 0.226 0.0126 0.18 0.206 -0.00425 -0.07 0.0766 0.3963 3124296 ChemDiv3_015172 CC1CCCC(C)N1CCCNC(=O)Cn2ncc3COc4ccc(C)cc4-c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B15 compound treatment 0.222 0.00856 0.12 0.197 -0.0133 -0.22 -0.0706 -0.2783 3040042 ChemDiv3_015173 O=C(Cn1nc(Cc2ccncc2)c3ccccc3c1=O)NCCCN4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B16 compound treatment 0.206 -0.00744 -0.11 0.19 -0.0203 -0.34 -0.3156 -0.886 3040045 ChemDiv3_015174 CCN1CCN(CC1)c2c(cnc3ccccc23)C(=O)c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B17 compound treatment 0.209 -0.00444 -0.06 0.201 -0.00925 -0.16 -0.1547 -0.9221 3040047 ChemDiv3_015175 CCOc1ccc(cc1)c2nc(SCC(=O)OC)c3Cc4cccc(OCC)c4Oc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B18 compound treatment 0.221 0.00756 0.11 0.215 0.00475 0.08 0.1329 0.9887 3040050 ChemDiv3_015176 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B19 compound treatment 0.233 0.0196 0.28 0.225 0.0147 0.25 0.3729 0.9981 3040053 ChemDiv3_015177 O=C(N1CCC2(CC1)OCCO2)c3ccc4SCCN(Cc5ccccc5)c4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B20 compound treatment 0.236 0.0226 0.32 0.207 -0.00325 -0.05 0.1896 0.5794 3040055 ChemDiv3_015178 CN1C(=O)CSc2ccc(NC(=O)NCc3cccnc3)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B21 compound treatment 0.26 0.0466 0.67 0.239 0.0288 0.48 0.8122 0.9875 3124297 ChemDiv3_015179 CCN1CCSc2ccc(cc12)C(=O)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B22 compound treatment 0.221 0.00756 0.11 0.238 0.0278 0.47 0.4058 0.8487 3040058 ChemDiv3_015180 Cc1ccccc1NC(=O)Cn2ncc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B23 mock treatment 0.217 0.00356 0.05 0.225 0.0147 0.25 0.2111 0.8351 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 B24 mock treatment 0.212 -0.00144 -0.02 0.214 0.00375 0.06 0.03 0.4526 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C01 compound treatment 0.226 0.0126 0.18 0.229 0.0187 0.31 0.3496 0.9647 3124298 ChemDiv3_015181 COC(=O)Cc1nc(no1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C02 compound treatment 0.192 -0.0214 -0.31 0.187 -0.0233 -0.39 -0.4928 -0.9929 3124299 ChemDiv3_015182 Cc1cc2NC(=O)CC(c3ccncc3)c2cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C03 compound treatment 0.231 0.0176 0.25 0.047 -0.163 -2.74 -1.7598 -0.6396 3040131 ChemDiv3_015183 O=C(Cc1c[nH]c2ccccc12)NC3(CCCCC3)C(=O)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C04 compound treatment 0.246 0.0326 0.47 0.239 0.0288 0.48 0.6706 0.9998 3040134 ChemDiv3_015184 O=c1[nH]c2ccc(NS(=O)(=O)c3ccc(cc3)C4CCCCC4)cc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C05 compound treatment 0.207 -0.00644 -0.09 0.182 -0.0283 -0.47 -0.4004 -0.8289 3040136 ChemDiv3_015185 COc1ccc(cc1)C2C(CC(=O)N2c3ccc(OC)cc3)C(=O)Nc4ccc(C)c(F)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C06 compound treatment 0.04 -0.173 -2.48 0.04 -0.17 -2.86 -3.7747 -0.9975 3040138 ChemDiv3_015186 CCc1cccc(NCC(O)Cn2nnnc2c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C07 compound treatment 0.217 0.00356 0.05 0.229 0.0187 0.31 0.2586 0.811 3040141 ChemDiv3_015187 Cc1ccc(Cn2c(=O)n(Cc3ccccc3)c(=O)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C08 compound treatment 0.19 -0.0234 -0.34 0.062 -0.148 -2.49 -1.9965 -0.7952 3040143 ChemDiv3_015188 CC(C)CCNS(=O)(=O)c1c(C)nc2sccn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C09 compound treatment 0.229 0.0156 0.22 0.193 -0.0173 -0.29 -0.0473 -0.1296 3040144 ChemDiv3_015189 OC(=O)c1ccc(cc1)N2CCCS2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C10 compound treatment 0.205 -0.00844 -0.12 0.062 -0.148 -2.49 -1.8448 -0.7405 3124300 ChemDiv3_015190 O=C1CC(CN1c2ccccc2)c3nnc(o3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C11 compound treatment 0.04 -0.173 -2.48 0.04 -0.17 -2.86 -3.7747 -0.9975 3040149 ChemDiv3_015191 CCSc1nc2sc3CN(CCc3c2c(=O)n1c4ccccc4)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C12 compound treatment 0.205 -0.00844 -0.12 0.039 -0.171 -2.87 -2.1177 -0.7361 3124301 ChemDiv3_015192 OC1=NC2C=NN(C(=O)C2N=C1O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C13 compound treatment 0.215 0.00156 0.02 0.04 -0.17 -2.86 -2.0047 -0.7016 3040214 ChemDiv3_015193 CC1Oc2ccc(C)cc2N(CCC(=O)N3CCC4(CC3)OCCO4)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C14 compound treatment 0.195 -0.0184 -0.26 0.218 0.00775 0.13 -0.0945 -0.3214 3040218 ChemDiv3_015194 CCCN(CCC)Cc1nnc(o1)c2cccc(Br)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C15 compound treatment 0.205 -0.00844 -0.12 0.205 -0.00525 -0.09 -0.1476 -0.9881 3040219 ChemDiv3_015195 CC1(CCC(=O)N1CCc2ccccc2)C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C16 compound treatment 0.04 -0.173 -2.48 0.041 -0.169 -2.84 -3.7629 -0.9977 3040223 ChemDiv3_015196 CC1CN(CCN1c2cccc(C)c2)C(=O)CN3CCN(Cc4ccc(Cl)cc4)C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C17 compound treatment 0.04 -0.173 -2.48 0.201 -0.00925 -0.16 -1.864 -0.7499 3040225 ChemDiv3_015197 O=C(NCC1CCCO1)C2N(C3CCCCCC3)C(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C18 compound treatment 0.174 -0.0394 -0.56 0.225 0.0147 0.25 -0.2238 -0.3633 3040228 ChemDiv3_015198 O=c1[nH]c2ncccc2nc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C19 compound treatment 0.04 -0.173 -2.48 0.04 -0.17 -2.86 -3.7747 -0.9975 3040229 ChemDiv3_015199 Cc1ccccc1NC(=O)NCCCN2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C20 compound treatment 0.201 -0.0124 -0.18 0.184 -0.0262 -0.44 -0.4373 -0.9204 3124302 ChemDiv3_015200 CCOC(=O)CCc1c(C)nn(c1C)c2ccc(Cl)nn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C21 compound treatment 0.184 -0.0294 -0.42 0.211 7.5E-4 0.01 -0.2888 -0.6857 3124303 ChemDiv3_015201 CC1CC(C)CN(C1)C(=O)C2C(N(C)C(=O)c3ccccc23)c4cn(C)c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C22 compound treatment 0.227 0.0136 0.19 0.166 -0.0442 -0.74 -0.388 -0.5055 3040234 ChemDiv3_015202 Clc1cccc(NCc2cccc3CN(CC4CCCO4)Cc32)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C23 mock treatment 0.207 -0.00644 -0.09 0.209 -0.00125 -0.02 -0.0799 -0.8465 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 C24 mock treatment 0.204 -0.00944 -0.13 0.173 -0.0372 -0.63 -0.5375 -0.8404 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D01 compound treatment 0.209 -0.00444 -0.06 0.224 0.0138 0.23 0.1183 0.4943 3040297 ChemDiv3_015203 CC(NC(=O)c1cccc2CN(Cc3cccnc3)C(=O)c21)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D02 compound treatment 0.202 -0.0114 -0.16 0.202 -0.00825 -0.14 -0.2136 -0.9966 3040299 ChemDiv3_015204 Cc1oc(nc1CS(=O)(=O)CC(=O)NCCN2CCOCC2)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D03 compound treatment 0.219 0.00556 0.08 0.216 0.00575 0.1 0.1245 0.9954 3040301 ChemDiv3_015205 Cc1cc(NS(=O)(=O)c2ccc3NC(=O)Cc3c2)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D04 compound treatment 0.204 -0.00944 -0.13 0.234 0.0238 0.4 0.1864 0.4429 3040303 ChemDiv3_015206 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCCn3nc(c4ccccc4)c5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D05 compound treatment 0.244 0.0306 0.44 0.221 0.0107 0.18 0.4367 0.9234 3040305 ChemDiv3_015207 CCn1c(C)c(CCC(=O)Nc2ccc(cc2)C(=O)OC)c(=O)n3nc(cc13)c4ccccc4OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D06 compound treatment 0.268 0.0546 0.78 0.241 0.0308 0.52 0.9168 0.9798 3124304 ChemDiv3_015208 CC(=O)N1CCc2c(C1)sc3n(Cc4cccc(C)c4)c(=O)n(Cc5ccccc5)c(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D07 compound treatment 0.206 -0.00744 -0.11 0.233 0.0227 0.38 0.1948 0.4914 3040306 ChemDiv3_015209 Cc1nn(c2ccccc2Cl)c3nc(cc(C)c13)C(=O)NCc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D08 compound treatment 0.241 0.0276 0.39 0.237 0.0267 0.45 0.5962 0.9979 3124305 ChemDiv3_015210 O=C(Cn1ncc2COc3ccccc3-c21)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D09 compound treatment 0.229 0.0156 0.22 0.204 -0.00625 -0.1 0.0832 0.3382 3040309 ChemDiv3_015211 CN(CC(O)c1ccc2N(CCc2c1)C(=O)C)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D10 compound treatment 0.213 -4.38E-4 -0.01 0.178 -0.0323 -0.54 -0.3872 -0.7152 3124306 ChemDiv3_015212 CCOc1ccc(cc1)N(CC)c2nc(no2)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D11 compound treatment 0.204 -0.00944 -0.13 0.192 -0.0182 -0.31 -0.312 -0.9322 3124307 ChemDiv3_015213 CCOC(=O)c1c(nn2CN(CCc3ccccc3)CNc12)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D12 compound treatment 0.209 -0.00444 -0.06 0.232 0.0217 0.37 0.2132 0.5755 3040311 ChemDiv3_015214 O=C(CN1C(=O)CCSc2ccccc12)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D13 compound treatment 0.253 0.0396 0.57 0.222 0.0118 0.2 0.5396 0.9004 3124308 ChemDiv3_015215 Cc1cccc(c1)c2nnc(o2)C3CCN(CC3)S(=O)(=O)Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D14 compound treatment 0.225 0.0116 0.17 0.171 -0.0393 -0.66 -0.3489 -0.5136 3040313 ChemDiv3_015216 c1sc2nc3ccccc3n2c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D15 compound treatment 0.197 -0.0164 -0.24 0.183 -0.0273 -0.46 -0.4897 -0.9522 3124309 ChemDiv3_015217 Cn1nc(C(=O)NCCN2CCC(Cc3ccccc3)CC2)c4COc5ccccc5-c41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D16 compound treatment 0.189 -0.0244 -0.35 0.188 -0.0222 -0.37 -0.5112 -0.9995 3040315 ChemDiv3_015218 COc1ccc2ncc(c(N3CCCCC3C)c2c1)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D17 compound treatment 0.225 0.0116 0.17 0.253 0.0428 0.72 0.6243 0.8479 3124310 ChemDiv3_015219 CN(C)CCNC(=O)c1ccc(C)c(NC2=NC3CS(=O)(=O)CC3S2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D18 compound treatment 0.211 -0.00244 -0.03 0.21 -2.5E-4 0.0 -0.0276 -0.7865 3040318 ChemDiv3_015220 CCNC(=O)C1CCN(CC1)c2nc3c(C)cc(C)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D19 compound treatment 0.198 -0.0154 -0.22 0.159 -0.0512 -0.86 -0.7644 -0.8607 3124311 ChemDiv3_015221 Fc1ccc(CN2CCSc3ccc(cc23)C(=O)N4CCCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D20 compound treatment 0.232 0.0186 0.27 0.186 -0.0243 -0.41 -0.1001 -0.2059 3040338 ChemDiv3_015222 CCc1nnc(NC(=O)Nc2ccc3SCC(=O)N(C)c3c2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D21 compound treatment 0.223 0.00956 0.14 0.281 0.0707 1.19 0.9364 0.7834 3041514 ChemDiv3_015223 CCN1CCSc2ccc(cc12)C(=O)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D22 compound treatment 0.205 -0.00844 -0.12 0.242 0.0318 0.53 0.2915 0.5335 3041515 ChemDiv3_015224 CC(NC(=O)Cn1ncc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D23 mock treatment 0.246 0.0326 0.47 0.23 0.0198 0.33 0.5637 0.9861 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 D24 mock treatment 0.203 -0.0104 -0.15 0.209 -0.00125 -0.02 -0.1204 -0.7986 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E01 compound treatment 0.211 -0.00244 -0.03 0.19 -0.0203 -0.34 -0.265 -0.7756 3041516 ChemDiv3_015225 Clc1ccc(OCC(=O)Nc2ccc(cc2)c3nnc4CCCCCn34)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E02 compound treatment 0.194 -0.0194 -0.28 0.22 0.00975 0.16 -0.0809 -0.2507 3041517 ChemDiv3_015226 COCCN1C(C(C(=O)N2CCCC2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E03 compound treatment 0.188 -0.0254 -0.36 0.205 -0.00525 -0.09 -0.3196 -0.8537 3041518 ChemDiv3_015227 COCCN1C(C(C(=O)NCCN(C)C)c2ccccc2C1=O)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E04 compound treatment 0.202 -0.0114 -0.16 0.183 -0.0273 -0.46 -0.4391 -0.9039 3041519 ChemDiv3_015228 O=C(NCCc1ccccc1)c2nnc(CS(=O)(=O)c3ccccc3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E05 compound treatment 0.215 0.00156 0.02 0.203 -0.00725 -0.12 -0.0702 -0.5677 3124312 ChemDiv3_015229 COc1ccc(cc1)N2C(C(CC2=O)C(=O)NC3CCCCC3)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E06 compound treatment 0.195 -0.0184 -0.26 0.195 -0.0153 -0.26 -0.3675 -0.9999 3041520 ChemDiv3_015230 COc1cccc(CNCC(O)Cn2nnnc2c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E07 compound treatment 0.215 0.00156 0.02 0.251 0.0408 0.68 0.4994 0.7298 3124313 ChemDiv3_015231 Cn1ncc2c(=O)n(CC(=O)c3ccccc3)cnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E08 compound treatment 0.242 0.0286 0.41 0.197 -0.0133 -0.22 0.1316 0.283 3041521 ChemDiv3_015232 COc1ccc(Cc2nnn[nH]2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E09 compound treatment 0.217 0.00356 0.05 0.213 0.00275 0.05 0.0687 0.9988 3124314 ChemDiv3_015233 COC(=O)c1cnn2c(=O)cc(C)[nH]c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E10 compound treatment 0.195 -0.0184 -0.26 0.267 0.0568 0.95 0.487 0.4928 3124315 ChemDiv3_015234 Fc1ccc(Cc2nnc(o2)C(=O)N3CCCC3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E11 compound treatment 0.224 0.0106 0.15 0.223 0.0127 0.21 0.2581 0.9855 3041522 ChemDiv3_015235 COc1ccc(Cn2cc[nH]c(=O)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E12 compound treatment 0.24 0.0266 0.38 0.231 0.0208 0.35 0.5149 0.9991 3124316 ChemDiv3_015236 CNc1c(NC(=O)C2CN(C(=O)C2)c3ccccc3)c(=O)oc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E13 compound treatment 0.205 -0.00844 -0.12 0.235 0.0248 0.42 0.2084 0.4818 3041523 ChemDiv3_015237 CCn1cnc2cc(NCc3ccccc3OC)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E14 compound treatment 0.209 -0.00444 -0.06 0.184 -0.0262 -0.44 -0.3564 -0.8007 3124317 ChemDiv3_015238 CN(Cc1nnc(o1)c2cccc(Br)c2)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E15 compound treatment 0.22 0.00656 0.09 0.221 0.0107 0.18 0.194 0.9536 3041524 ChemDiv3_015239 COc1ccc(CCNC(=O)C2(C)CCC(=O)N2CCC(C)C)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E16 compound treatment 0.222 0.00856 0.12 0.223 0.0127 0.21 0.2379 0.9649 3124318 ChemDiv3_015240 O=C(CN1CCN(Cc2ccccc2)C1=O)NCCCN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E17 compound treatment 0.237 0.0236 0.34 0.225 0.0147 0.25 0.4134 0.9885 3124319 ChemDiv3_015241 CCc1ccc(CN2C(C(=O)NCC3CCCO3)c4ccccc4C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E18 compound treatment 0.185 -0.0284 -0.41 0.213 0.00275 0.05 -0.255 -0.6229 3041525 ChemDiv3_015242 Clc1nc2ncccc2nc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E19 compound treatment 0.193 -0.0204 -0.29 0.198 -0.0123 -0.21 -0.3521 -0.9852 3124320 ChemDiv3_015243 CCc1ccc(NC(=O)NCCCN2CCN(CC2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E20 compound treatment 0.23 0.0166 0.24 0.208 -0.00225 -0.04 0.1408 0.587 3041526 ChemDiv3_015244 CCOC(=O)CCc1c(C)nn(c1C)c2ccc(nn2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E21 compound treatment 0.193 -0.0204 -0.29 0.214 0.00375 0.06 -0.1622 -0.5424 3124321 ChemDiv3_015245 CN1C(C(C(=O)NC2CC2)c3ccccc3C1=O)c4cn(C)c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E22 compound treatment 0.216 0.00256 0.04 0.216 0.00575 0.1 0.0942 0.9121 3041527 ChemDiv3_015246 Cc1ccc(NCc2cccc3CN(CC4CCCO4)Cc32)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E23 mock treatment 0.204 -0.00944 -0.13 0.219 0.00875 0.15 0.0084 0.0421 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 E24 mock treatment 0.195 -0.0184 -0.26 0.222 0.0118 0.2 -0.047 -0.1428 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F01 compound treatment 0.206 -0.00744 -0.11 0.222 0.0118 0.2 0.0642 0.2866 3124322 ChemDiv3_015247 COCCN1Cc2cccc(C(=O)NCc3ccccn3)c2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F02 compound treatment 0.2 -0.0134 -0.19 0.235 0.0248 0.42 0.1578 0.3448 3124323 ChemDiv3_015248 COc1ccc(CCNC(=O)c2cc3sc(C)cc3n2C)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F03 compound treatment 0.199 -0.0144 -0.21 0.227 0.0168 0.28 0.0528 0.1513 3041528 ChemDiv3_015249 CCc1cccc(NS(=O)(=O)c2ccc3NC(=O)Cc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F04 compound treatment 0.214 5.62E-4 0.01 0.193 -0.0173 -0.29 -0.199 -0.6872 3124433 ChemDiv3_015250 O=C(CCCn1nc(c2ccccc2)c3ccccc13)NCc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F05 compound treatment 0.217 0.00356 0.05 0.219 0.00875 0.15 0.1399 0.8998 3041529 ChemDiv3_015251 CCCNC(=O)c1cc(C)c2c(C)nn(c3ccccc3)c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F06 compound treatment 0.244 0.0306 0.44 0.253 0.0428 0.72 0.8165 0.9718 3124434 ChemDiv3_015252 CCn1c(=O)n(c2ccccc2)c(=O)c3c4CCN(Cc4sc13)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F07 compound treatment 0.266 0.0526 0.75 0.236 0.0257 0.43 0.8372 0.9654 3124435 ChemDiv3_015253 Cc1nn(c2ccccc2Cl)c3nc(cc(C)c13)C(=O)NCC4CCN(C4)C5CCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F08 compound treatment 0.266 0.0526 0.75 0.262 0.0517 0.87 1.1458 0.9974 3041530 ChemDiv3_015254 CN(C(=O)Cn1ncc2COc3ccccc3-c21)c4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F09 compound treatment 0.27 0.0566 0.81 0.238 0.0278 0.47 0.9014 0.9656 3124436 ChemDiv3_015255 O=C(CCc1c[nH]c2ccccc12)N3CCn4c(C3)nc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F10 compound treatment 0.237 0.0236 0.34 0.239 0.0288 0.48 0.5795 0.9846 3041531 ChemDiv3_015256 COc1ccc(CNc2nc(no2)c3ccc(OC)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F11 compound treatment 0.278 0.0646 0.92 0.264 0.0537 0.9 1.2909 0.9999 3124437 ChemDiv3_015257 COc1cccc(NC(=O)c2ccnc(c2)N3CCC(CC3)C(=O)O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F12 compound treatment 0.253 0.0396 0.57 0.229 0.0187 0.31 0.6227 0.9616 3041532 ChemDiv3_015258 CC1CN(CCN1c2cccc(C)c2)C(=O)CN3C(=O)CCSc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F13 compound treatment 0.245 0.0316 0.45 0.259 0.0488 0.82 0.8978 0.9607 3124438 ChemDiv3_015259 O=C(CCc1nc2cccnc2n1c3ccccc3)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F14 compound treatment 0.251 0.0376 0.54 0.279 0.0688 1.15 1.1958 0.9395 3124439 ChemDiv3_015260 CCc1ccc2ncc(C(=O)c3ccccc3)c(N4CCOCC4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F15 compound treatment 0.25 0.0366 0.52 0.296 0.0858 1.44 1.3875 0.9061 3041533 ChemDiv3_015261 CCC(C)NC(=O)C1CCCN(C1)c2nc(no2)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F16 compound treatment 0.159 -0.0544 -0.78 0.2 -0.0103 -0.17 -0.6722 -0.843 3124440 ChemDiv3_015262 CCOc1ccc(Nc2c(cnc3ccc(OCC)cc23)S(=O)(=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F17 compound treatment 0.225 0.0116 0.17 0.21 -2.5E-4 0.0 0.114 0.6889 3124441 ChemDiv3_015263 COc1cccc(Nc2nnc(Cc3cccnc3)c4ccccc24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F18 compound treatment 0.228 0.0146 0.21 0.216 0.00575 0.1 0.2155 0.9388 3041534 ChemDiv3_015264 CCCNC(=O)Cn1nc(C)n2c(cc3cc(C)ccc32)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F19 compound treatment 0.287 0.0736 1.05 0.28 0.0698 1.17 1.5718 0.9986 3124442 ChemDiv3_015265 COc1cccc(NC(=O)c2ccc3SCCN(C)c3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F20 compound treatment 0.249 0.0356 0.51 0.214 0.00375 0.06 0.4042 0.7886 3041535 ChemDiv3_015266 CN1CC(=O)N=C1NC(=O)Nc2ccc3SCC(=O)N(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F21 compound treatment 0.265 0.0516 0.74 0.243 0.0328 0.55 0.9102 0.9895 3124443 ChemDiv3_015267 CCCNC(=O)c1ccc2SCCN(CC)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F22 compound treatment 0.217 0.00356 0.05 0.204 -0.00625 -0.1 -0.0381 -0.3271 3124444 ChemDiv3_015268 CC1CCc2nc3sc(NC(=O)Nc4ccccc4C)c(C)c3c(=O)n2CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F23 mock treatment 0.234 0.0206 0.29 0.217 0.00675 0.11 0.2881 0.914 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 F24 mock treatment 0.209 -0.00444 -0.06 0.216 0.00575 0.1 0.0234 0.2022 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G01 compound treatment 0.188 -0.0254 -0.36 0.207 -0.00325 -0.05 -0.2959 -0.8041 1720454 ChemDiv3_015269 CCOc1ccc(cc1)C(=O)N2CC(=O)Nc3ccc(C)cc3C2c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G02 compound treatment 0.214 5.62E-4 0.01 0.202 -0.00825 -0.14 -0.0922 -0.6649 3124445 ChemDiv3_015270 COCCN1C(C(C(=O)NC2CCCC2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G03 compound treatment 0.206 -0.00744 -0.11 0.223 0.0127 0.21 0.0761 0.3184 3124446 ChemDiv3_015271 CCCCN(CC)C(=O)C1C(N(CCOC)C(=O)c2ccccc12)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G04 compound treatment 0.191 -0.0224 -0.32 0.213 0.00275 0.05 -0.1943 -0.5992 3041536 ChemDiv3_015272 COc1cccc(CNC(=O)c2nnc(CS(=O)(=O)c3ccccc3)o2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G05 compound treatment 0.228 0.0146 0.21 0.258 0.0478 0.8 0.714 0.8622 1483093 ChemDiv3_015273 Cn1c(CNc2ccc(F)cc2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G06 compound treatment 0.269 0.0556 0.79 0.228 0.0177 0.3 0.7726 0.9103 3124447 ChemDiv3_015274 Cc1cc(Nc2ccc(cc2)C(=O)Nc3ccc4OCOc4c3)n5ncnc5n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G07 compound treatment 0.248 0.0346 0.49 0.263 0.0527 0.89 0.9756 0.9621 3124448 ChemDiv3_015275 Cc1ccc(Cl)cc1NC(=O)Cn2cnc3n(C)ncc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G08 compound treatment 0.286 0.0726 1.04 0.244 0.0338 0.57 1.1345 0.9594 3041537 ChemDiv3_015276 COc1cccc(CNS(=O)(=O)c2c(C)nc3sccn3c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G09 compound treatment 0.288 0.0746 1.07 0.253 0.0428 0.72 1.2615 0.9814 3124449 ChemDiv3_015277 COC(=O)c1cnn2c(=O)c3CCCc3[nH]c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G10 compound treatment 0.265 0.0516 0.74 0.279 0.0688 1.15 1.3374 0.9766 3041538 ChemDiv3_015278 CCN1CCN(CC1)C(=O)c2cccc(Nc3nc4ccccc4n5nnnc35)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G11 compound treatment 0.234 0.0206 0.29 0.216 0.00575 0.1 0.2762 0.8923 3124450 ChemDiv3_015279 Cc1noc(CCn2c(=O)[nH]c3ccccc3c2=O)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G12 compound treatment 0.243 0.0296 0.42 0.271 0.0607 1.02 1.02 0.924 3124451 ChemDiv3_015280 CC1CCN(CC1)c2ccc(NS(=O)(=O)c3c(C)nc4sccn4c3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G13 compound treatment 0.216 0.00256 0.04 0.248 0.0377 0.63 0.4739 0.7468 3041539 ChemDiv3_015281 Cn1cnc2cc(NCc3ccccn3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G14 compound treatment 0.239 0.0256 0.37 0.234 0.0238 0.4 0.5404 0.9991 3124452 ChemDiv3_015282 COc1cccc(CNC(=O)c2ccc(Nc3nc4ccccc4n5nnnc35)cc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G15 compound treatment 0.232 0.0186 0.27 0.2 -0.0103 -0.17 0.0661 0.2089 3041540 ChemDiv3_015283 CC1CCCC(NC(=O)C2N(CCc3ccccc3)C(=O)c4ccccc24)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G16 compound treatment 0.282 0.0686 0.98 0.219 0.00875 0.15 0.7973 0.804 3124453 ChemDiv3_015284 COc1ccc(cc1)N2CCN(CCCNS(=O)(=O)c3c(C)noc3C)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G17 compound treatment 0.276 0.0626 0.89 0.28 0.0698 1.17 1.4606 0.9912 3124454 ChemDiv3_015285 COc1ccc(CN2C(C(=O)NCCCN3CC(C)CC(C)C3)c4ccccc4C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G18 compound treatment 0.262 0.0486 0.69 0.267 0.0568 0.95 1.1647 0.988 3041541 ChemDiv3_015286 Cc1nn(c2ccc(C)c(C)c2)c3nc(cc(C)c13)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G19 compound treatment 0.241 0.0276 0.39 0.188 -0.0222 -0.37 0.0147 0.0271 3124455 ChemDiv3_015287 Clc1ccc(NC(=O)NCC2CCN(Cc3cccc(Cl)c3)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G20 compound treatment 0.222 0.00856 0.12 0.208 -0.00225 -0.04 0.0599 0.4674 3041542 ChemDiv3_015288 CCOC(=O)CCc1c(C)nn(c1C)c2ccc3nnc(C)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G21 compound treatment 0.207 -0.00644 -0.09 0.22 0.00975 0.16 0.0506 0.2695 3124456 ChemDiv3_015289 CCc1cccc(NC(=O)C2C(N(C)C(=O)c3ccccc23)c4cn(C)c5ccccc45)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G22 compound treatment 0.191 -0.0224 -0.32 0.178 -0.0323 -0.54 -0.6097 -0.9689 3041543 ChemDiv3_015290 COc1cccc(NCc2cccc3CN(CC4CCCO4)Cc32)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G23 mock treatment 0.187 -0.0264 -0.38 0.201 -0.00925 -0.16 -0.3772 -0.9227 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 G24 mock treatment 0.213 -4.38E-4 -0.01 0.166 -0.0442 -0.74 -0.5296 -0.713 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H01 compound treatment 0.234 0.0206 0.29 0.221 0.0107 0.18 0.3356 0.9725 3124457 ChemDiv3_015291 COCCN1Cc2cccc(C(=O)N3CCN(CC3)C4CCCCC4)c2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H02 compound treatment 0.206 -0.00744 -0.11 0.211 7.5E-4 0.01 -0.0663 -0.6191 3124458 ChemDiv3_015292 CCc1cc2n(C)c(cc2s1)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H03 compound treatment 0.221 0.00756 0.11 0.206 -0.00425 -0.07 0.026 0.201 3041544 ChemDiv3_015293 CCOC(=O)C1CCCN(C1)C(=O)c2ccc(CS(=O)c3ccccc3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H04 compound treatment 0.203 -0.0104 -0.15 0.212 0.00175 0.03 -0.0848 -0.5573 3124701 ChemDiv3_015294 CCCCN(C1CCN(CC1)C(=O)C)C(=O)c2cc3COc4ccccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H05 compound treatment 0.246 0.0326 0.47 0.187 -0.0233 -0.39 0.0534 0.0879 3041545 ChemDiv3_015295 CC1CCN(CC1)C(=O)c2cc(C)c3c(C)nn(c4ccccc4)c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H06 compound treatment 0.204 -0.00944 -0.13 0.234 0.0238 0.4 0.1864 0.4429 3124568 ChemDiv3_015296 COc1cccc(Cn2c(=O)n(Cc3ccccc3)c(=O)c4cccnc24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H07 compound treatment 0.219 0.00556 0.08 0.228 0.0177 0.3 0.2669 0.8656 3124569 ChemDiv3_015297 CC1CCN(CC1)C(=O)CCc2c(C)nc3n(C)c(=O)n(C)c(=O)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H08 compound treatment 0.209 -0.00444 -0.06 0.226 0.0158 0.26 0.142 0.5225 3041546 ChemDiv3_015298 O=C(Cn1ncc2COc3ccccc3-c21)Nc4nccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H09 compound treatment 0.249 0.0356 0.51 0.25 0.0398 0.67 0.8314 0.991 3124570 ChemDiv3_015299 CN(C)CC(O)c1ccc2cc[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H10 compound treatment 0.238 0.0246 0.35 0.234 0.0238 0.4 0.5303 0.998 3041547 ChemDiv3_015300 COc1ccc(cc1)c2noc(n2)N(C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H11 compound treatment 0.225 0.0116 0.17 0.278 0.0678 1.14 0.921 0.8015 3041694 ChemDiv3_015301 CCS(=O)(=O)N1CCC(=CC1)c2c(C)n(CC(=O)N3CCCC3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H12 compound treatment 0.222 0.00856 0.12 0.257 0.0468 0.78 0.6414 0.8077 3041695 ChemDiv3_015302 CCOc1ccc(NC(=O)CC2Oc3ccccc3NC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H13 compound treatment 0.238 0.0246 0.35 0.255 0.0447 0.75 0.7795 0.9401 3041696 ChemDiv3_015303 CC(C)NC(=O)CCc1nc2cccnc2n1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H14 compound treatment 0.202 -0.0114 -0.16 0.231 0.0208 0.35 0.1306 0.3394 3041697 ChemDiv3_015304 CCOC(=O)C1CCN(CC1)c2c(cnc3ccc(CC)cc23)C(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H15 compound treatment 0.248 0.0346 0.49 0.248 0.0377 0.63 0.7976 0.9925 3041699 ChemDiv3_015305 C1CCN(C1)c2ncnc3n4CCCCCc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H16 compound treatment 0.271 0.0576 0.82 0.219 0.00875 0.15 0.686 0.8203 3041700 ChemDiv3_015306 CCOc1ccc(CCNC(=O)C(C)N2C(=O)CC(C)(C)Sc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H17 compound treatment 0.264 0.0506 0.72 0.263 0.0527 0.89 1.1374 0.995 3124571 ChemDiv3_015307 O=C(Cn1nc(Cc2ccncc2)c3ccccc3c1=O)N4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H18 compound treatment 0.251 0.0376 0.54 0.253 0.0428 0.72 0.8873 0.9898 3041701 ChemDiv3_015308 CCC(C)NC(=O)CSc1cc(C)nc2c(c(C)nn12)c3ccccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H19 compound treatment 0.298 0.0846 1.21 0.239 0.0288 0.48 1.1965 0.9188 3041759 ChemDiv3_015309 CCNC(=O)c1ccc2SCCN(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H20 compound treatment 0.232 0.0186 0.27 0.211 7.5E-4 0.01 0.1966 0.7398 3041760 ChemDiv3_015310 CN1C(=O)CSc2ccc(NC(=O)N3CCOCC3)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H21 compound treatment 0.241 0.0276 0.39 0.246 0.0357 0.6 0.7031 0.9792 3041762 ChemDiv3_015311 CCN1CCSc2ccc(cc12)C(=O)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H22 compound treatment 0.254 0.0406 0.58 0.25 0.0398 0.67 0.882 0.9976 3041763 ChemDiv3_015312 Cc1ccc(CN2C(=O)CSc3ccc(NC(=O)NCc4ccccc4)cc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H23 mock treatment 0.201 -0.0124 -0.18 0.227 0.0168 0.28 0.073 0.2194 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 H24 mock treatment 0.201 -0.0124 -0.18 0.196 -0.0143 -0.24 -0.2949 -0.9894 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I01 compound treatment 0.185 -0.0284 -0.41 0.184 -0.0262 -0.44 -0.5992 -0.9992 1630475 ChemDiv3_015313 Brc1ccc2NC(=O)CN(C(c3ccccc3)c2c1)C(=O)CC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I02 compound treatment 0.198 -0.0154 -0.22 0.195 -0.0153 -0.26 -0.3371 -0.9973 3041765 ChemDiv3_015314 NC(=O)c1nnc(Cc2ccc(Cl)cc2Cl)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I03 compound treatment 0.215 0.00156 0.02 0.198 -0.0123 -0.21 -0.1296 -0.6266 3124572 ChemDiv3_015315 COc1ccc(cc1)C2C(C(=O)Nc3cnc4ccccc4c3)c5ccccc5C(=O)N2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I04 compound treatment 0.28 0.0666 0.95 0.2 -0.0103 -0.17 0.5516 0.5701 3041767 ChemDiv3_015316 OC(CNCCc1ccccc1)Cn2nnnc2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I05 compound treatment 0.244 0.0306 0.44 0.213 0.00275 0.05 0.3418 0.7774 3124573 ChemDiv3_015317 CC1CC(C)CN(C1)C(=O)C2C(N(C)C(=O)c3ccccc23)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I06 compound treatment 0.27 0.0566 0.81 0.206 -0.00425 -0.07 0.5216 0.6423 3041769 ChemDiv3_015318 OC(CN1CCN(CC1)c2cccnc2)Cn3nnnc3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I07 compound treatment 0.252 0.0386 0.55 0.264 0.0537 0.9 1.0279 0.9721 3124574 ChemDiv3_015319 Cc1ccc(Cn2cnc3n(C)ncc3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I08 compound treatment 0.245 0.0316 0.45 0.269 0.0587 0.99 1.0165 0.9373 3041770 ChemDiv3_015320 Cc1nc2sccn2c(=O)c1S(=O)(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I09 compound treatment 0.21 -0.00344 -0.05 0.263 0.0527 0.89 0.5913 0.6668 3124575 ChemDiv3_015321 CC(C)CCn1c(=O)c2sccc2n3c(CCCC(=O)O)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I10 compound treatment 0.244 0.0306 0.44 0.245 0.0348 0.58 0.7215 0.9899 3041772 ChemDiv3_015322 CCc1nn2c(=O)c(c(C)nc2s1)S(=O)(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I11 compound treatment 0.191 -0.0224 -0.32 0.183 -0.0273 -0.46 -0.5503 -0.985 3124576 ChemDiv3_015323 Oc1ccccc1C2=NC(NC(C2)c3cccnc3)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I12 compound treatment 0.217 0.00356 0.05 0.239 0.0288 0.48 0.3772 0.7775 3124577 ChemDiv3_015324 CN1c2ccccc2Oc3nnc(NCc4ccccc4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I13 compound treatment 0.25 0.0366 0.52 0.209 -0.00125 -0.02 0.355 0.6782 3041775 ChemDiv3_015325 CCn1cnc2cc(NCc3ccccn3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I14 compound treatment 0.303 0.0896 1.28 0.253 0.0428 0.72 1.4132 0.9625 3124578 ChemDiv3_015326 COc1ccc(CCNc2cc3N(C)c4ccccc4Oc3nn2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I15 compound treatment 0.245 0.0316 0.45 0.165 -0.0452 -0.76 -0.2178 -0.2465 3124579 ChemDiv3_015327 CC(CCc1ccccc1)N2C(C(=O)NCCc3ccccc3)c4ccccc4C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I16 compound treatment 0.227 0.0136 0.19 0.19 -0.0203 -0.34 -0.1032 -0.2636 3041777 ChemDiv3_015328 CCc1nc2n(ncc2c(=O)n1c3ccc(OC)c(Cl)c3)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I17 compound treatment 0.26 0.0466 0.67 0.269 0.0587 0.99 1.1682 0.9817 3041779 ChemDiv3_015329 Clc1ccc2[nH]c(=O)n(Cc3ccccc3)c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I18 compound treatment 0.224 0.0106 0.15 0.207 -0.00325 -0.05 0.0683 0.425 3124580 ChemDiv3_015330 CCc1ccc(NCc2c(cnn2c3ccccc3)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I19 compound treatment 0.229 0.0156 0.22 0.179 -0.0313 -0.52 -0.2135 -0.3747 3124581 ChemDiv3_015331 CCc1ccc(NC(=O)NCCCN2CCCc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I20 compound treatment 0.223 0.00956 0.14 0.206 -0.00425 -0.07 0.0463 0.3 3041781 ChemDiv3_015332 Cc1nn(c(C)c1CCC(=O)O)c2ccc3nnc(C)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I21 compound treatment 0.189 -0.0244 -0.35 0.215 0.00475 0.08 -0.1908 -0.5322 1362464 ChemDiv3_015333 Cc1ccn2c(NC3CCCC3)c(nc2c1)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I22 compound treatment 0.195 -0.0184 -0.26 0.219 0.00875 0.15 -0.0826 -0.2738 3041783 ChemDiv3_015334 COC(=O)c1cc(NC(=O)c2cccc3CN(Cc4cccnc4)C(=O)c32)cc(c1)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I23 mock treatment 0.191 -0.0224 -0.32 0.222 0.0118 0.2 -0.0875 -0.2323 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 I24 mock treatment 0.189 -0.0244 -0.35 0.178 -0.0323 -0.54 -0.6299 -0.9776 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J01 compound treatment 0.236 0.0226 0.32 0.207 -0.00325 -0.05 0.1896 0.5794 3041876 ChemDiv3_015335 COCCN1Cc2cccc(C(=O)N3CCN(CC3)c4ccc(F)cc4)c2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J02 compound treatment 0.134 -0.0794 -1.14 0.137 -0.0732 -1.23 -1.6728 -0.9992 3041817 ChemDiv3_015336 Fc1ccc(NC(=O)CCCn2nc(c3ccccc3)c4cc(Cl)ccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J03 compound treatment 0.26 0.0466 0.67 0.209 -0.00125 -0.02 0.4561 0.6845 3041819 ChemDiv3_015337 Clc1ccc(CCNC(=O)c2ccc(CS(=O)c3ccc(Cl)cc3)o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J04 compound treatment 0.262 0.0486 0.69 0.202 -0.00825 -0.14 0.3933 0.5552 3041820 ChemDiv3_015338 CCOC(=O)c1c(NC(=O)CN2C(=O)CCSc3ccccc23)sc4CCCCc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J05 compound treatment 0.255 0.0416 0.59 0.245 0.0348 0.58 0.8328 1.0 3041821 ChemDiv3_015339 O=C(NCc1ccccc1)c2cnc(nc2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J06 compound treatment 0.257 0.0436 0.62 0.252 0.0418 0.7 0.9361 0.9983 3041822 ChemDiv3_015340 Clc1ccc(Cn2c(=O)n(C3CCCCC3)c(=O)c4cccnc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J07 compound treatment 0.26 0.0466 0.67 0.213 0.00275 0.05 0.5036 0.7543 3041824 ChemDiv3_015341 COc1ccc(cc1)c2cc3c(cc(NC(=O)c4ccco4)cc3n2C)S(=O)(=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J08 compound treatment 0.237 0.0236 0.34 0.24 0.0297 0.5 0.5914 0.9817 3124582 ChemDiv3_015342 CC1CCCCN1CCNC(=O)Cn2ncc3COc4ccccc4-c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J09 compound treatment 0.252 0.0386 0.55 0.248 0.0377 0.63 0.8381 0.9976 3041826 ChemDiv3_015343 CCc1ccc(cc1)N2Cc3ccncc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J10 compound treatment 0.227 0.0136 0.19 0.271 0.0607 1.02 0.8582 0.8268 3124583 ChemDiv3_015344 COc1ccc(cc1)c2noc(n2)N(CCC#N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J11 compound treatment 0.255 0.0416 0.59 0.243 0.0328 0.55 0.8091 0.9992 3041828 ChemDiv3_015345 COc1ccc(Cl)cc1S(=O)(=O)N2CCC(CC2)c3nnc(o3)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J12 compound treatment 0.264 0.0506 0.72 0.217 0.00675 0.11 0.5915 0.808 3124584 ChemDiv3_015346 O=C(CC1Oc2ccccc2NC1=O)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J13 compound treatment 0.241 0.0276 0.39 0.196 -0.0143 -0.24 0.1097 0.2378 3124585 ChemDiv3_015347 O=C(CCc1nc2cccnc2n1Cc3cccs3)N4CCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J14 compound treatment 0.086 -0.127 -1.82 0.091 -0.119 -2.0 -2.7042 -0.9989 3041830 ChemDiv3_015348 COc1ccc2ncc(C(=O)c3ccccc3)c(N4CCCCC4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J15 compound treatment 0.222 0.00856 0.12 0.216 0.00575 0.1 0.1548 0.993 1181891 ChemDiv3_015349 Cc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2N4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J16 compound treatment 0.274 0.0606 0.87 0.275 0.0648 1.09 1.381 0.9937 3041832 ChemDiv3_015350 O=C(NCc1ccco1)C2CCN(CC2)c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J17 compound treatment 0.227 0.0136 0.19 0.247 0.0367 0.62 0.5733 0.8867 3124586 ChemDiv3_015351 CN(C)CCN(Cc1ccco1)C(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J18 compound treatment 0.241 0.0276 0.39 0.241 0.0308 0.52 0.6437 0.9912 3041834 ChemDiv3_015352 OC(=O)CCC(=O)n1ncc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J19 compound treatment 0.28 0.0666 0.95 0.252 0.0418 0.7 1.1687 0.9886 3124587 ChemDiv3_015353 CN1CCSc2ccc(cc12)C(=O)NCCCN3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J20 compound treatment 0.253 0.0396 0.57 0.239 0.0288 0.48 0.7414 0.9969 3124588 ChemDiv3_015354 O=C(Cn1ncc2ccccc12)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J21 compound treatment 0.239 0.0256 0.37 0.254 0.0437 0.73 0.7778 0.9482 3041836 ChemDiv3_015355 CCN1CCSc2ccc(cc12)C(=O)NCCCN3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J22 compound treatment 0.263 0.0496 0.71 0.185 -0.0253 -0.42 0.2016 0.2441 3124589 ChemDiv3_015356 CC1CCC(CC1)NC(=O)Nc2ccc3SCC(=O)N(Cc4ccc(C)cc4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J23 mock treatment 0.223 0.00956 0.14 0.251 0.0408 0.68 0.5803 0.832 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 J24 mock treatment 0.206 -0.00744 -0.11 0.182 -0.0283 -0.47 -0.4105 -0.8448 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K01 compound treatment 0.231 0.0176 0.25 0.265 0.0548 0.92 0.8274 0.8685 3124590 ChemDiv3_015357 O=C(NC1(CCCCC1)C(=O)Nc2ccc3OCOc3c2)/C=C\c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K02 compound treatment 0.209 -0.00444 -0.06 0.21 -2.5E-4 0.0 -0.0478 -0.7522 3041839 ChemDiv3_015358 CCCc1nc2nc(C)cc(Cl)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K03 compound treatment 0.238 0.0246 0.35 0.214 0.00375 0.06 0.2929 0.8207 3041840 ChemDiv3_015359 COc1ccc(cc1)C2C(C(=O)N(C)c3ccc(cc3)C(C)C)c4ccccc4C(=O)N2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K04 compound treatment 0.264 0.0506 0.72 0.221 0.0107 0.18 0.639 0.8572 3124591 ChemDiv3_015360 CC(NCC(O)Cn1nnnc1c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K05 compound treatment 0.193 -0.0204 -0.29 0.222 0.0118 0.2 -0.0673 -0.1907 3041842 ChemDiv3_015361 C1CCC(CC1)Nc2c(nc3cnccn23)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K06 compound treatment 0.258 0.0446 0.64 0.238 0.0278 0.47 0.7801 0.9881 3124592 ChemDiv3_015362 Cc1nc2sccn2c(=O)c1S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K07 compound treatment 0.218 0.00456 0.07 0.196 -0.0143 -0.24 -0.123 -0.496 3124593 ChemDiv3_015363 COc1ccccc1CNC(=O)c2ccc3c(=O)[nH]c4c(nnn4c3c2)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K08 compound treatment 0.221 0.00756 0.11 0.239 0.0288 0.48 0.4177 0.8447 3041877 ChemDiv3_015364 CCOC(=O)c1nnc(Cc2ccccc2OC)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K09 compound treatment 0.257 0.0436 0.62 0.218 0.00775 0.13 0.5326 0.8367 3041879 ChemDiv3_015365 Fc1ccc(CNC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K10 compound treatment 0.262 0.0486 0.69 0.259 0.0488 0.82 1.0697 0.9967 3041880 ChemDiv3_015366 C(N1CCc2ccccc2C1)c3nnc(o3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K11 compound treatment 0.276 0.0626 0.89 0.243 0.0328 0.55 1.0215 0.9726 3041881 ChemDiv3_015367 NC1=NC(Cc2ccccc2)CC(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K12 compound treatment 0.267 0.0536 0.77 0.206 -0.00425 -0.07 0.4913 0.6385 3041883 ChemDiv3_015368 C(N1CCCCCC1)c2nnc(o2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K13 compound treatment 0.223 0.00956 0.14 0.214 0.00375 0.06 0.1412 0.9379 3041884 ChemDiv3_015369 CCCn1cnc2cc(NCc3ccncc3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K14 compound treatment 0.224 0.0106 0.15 0.263 0.0527 0.89 0.7329 0.816 3041885 ChemDiv3_015370 CCNc1c(NS(=O)(=O)c2ccc(cc2)C3CCCCC3)c(=O)oc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K15 compound treatment 0.288 0.0746 1.07 0.286 0.0757 1.27 1.6531 0.9962 3124702 ChemDiv3_015371 CCc1ccc(CN2C(C(=O)NCCc3ccccc3)c4ccccc4C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K16 compound treatment 0.246 0.0326 0.47 0.235 0.0248 0.42 0.6231 0.9984 3041887 ChemDiv3_015372 CN(Cc1ccccc1)C(=O)c2ccc(cc2)N3CCCC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K17 compound treatment 0.217 0.00356 0.05 0.208 -0.00225 -0.04 0.0093 0.1471 3124703 ChemDiv3_015373 CC(C)(C)C(=O)Cn1c(=O)n(CC2CCC(CC2)C(=O)NCc3ccccc3)c(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K18 compound treatment 0.282 0.0686 0.98 0.246 0.0357 0.6 1.1177 0.9722 3041889 ChemDiv3_015374 OC(=O)C1CCN(CC1)c2nc3ncccc3nc2c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K19 compound treatment 0.248 0.0346 0.49 0.24 0.0297 0.5 0.7026 1.0 3124704 ChemDiv3_015375 CCCN1CCN(CCNC(=O)Nc2ccccc2OC)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K20 compound treatment 0.268 0.0546 0.78 0.234 0.0238 0.4 0.8337 0.9514 3041891 ChemDiv3_015376 N(c1ccccc1)c2cnccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K21 compound treatment 0.204 -0.00944 -0.13 0.222 0.0118 0.2 0.044 0.1841 3124705 ChemDiv3_015377 C1COc2cc(Nc3c(nc4ccccn34)c5ccccc5)ccc2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K22 compound treatment 0.205 -0.00844 -0.12 0.192 -0.0182 -0.31 -0.3019 -0.9171 3041893 ChemDiv3_015378 O=C(NN1CCOCC1)c2cccc3CN(Cc4cccnc4)C(=O)c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K23 mock treatment 0.208 -0.00544 -0.08 0.223 0.0127 0.21 0.0963 0.423 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 K24 mock treatment 0.216 0.00256 0.04 0.163 -0.0473 -0.79 -0.5348 -0.6737 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L01 compound treatment 0.211 -0.00244 -0.03 0.24 0.0297 0.5 0.3284 0.6561 3124706 ChemDiv3_015379 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cccc4CN(C5CCCCC5)C(=O)c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L02 compound treatment 0.205 -0.00844 -0.12 0.195 -0.0153 -0.26 -0.2663 -0.9411 3124707 ChemDiv3_015380 Clc1ccc2n(CCCC(=O)NCCc3ccccc3)nc(c4ccccc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L03 compound treatment 0.266 0.0526 0.75 0.204 -0.00625 -0.1 0.4575 0.6026 3041895 ChemDiv3_015381 CC1CC(C)CN(C1)C(=O)c2ccc3S(=O)c4ccccc4C(=O)N(Cc5ccccc5)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L04 compound treatment 0.245 0.0316 0.45 0.248 0.0377 0.63 0.7673 0.9862 3124708 ChemDiv3_015382 COc1ccc(cc1)C2CC(=O)N(CC(=O)N3CCOCC3)c4ccccc4S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L05 compound treatment 0.226 0.0126 0.18 0.261 0.0508 0.85 0.7294 0.8378 3041897 ChemDiv3_015383 O=C(NC1CCCC1)c2cnc(nc2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L06 compound treatment 0.275 0.0616 0.88 0.216 0.00575 0.1 0.6909 0.7799 3124709 ChemDiv3_015384 CCc1ccc(NC(=O)Cn2c(=O)n(C3CCCCC3)c(=O)c4cccnc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L07 compound treatment 0.237 0.0236 0.34 0.224 0.0138 0.23 0.4015 0.9829 3124710 ChemDiv3_015385 COc1cccc(c1)c2cc([nH]n2)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L08 compound treatment 0.267 0.0536 0.77 0.227 0.0168 0.28 0.7405 0.9074 3041900 ChemDiv3_015386 CN(CCNC(=O)Cn1ncc2COc3ccccc3-c21)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L09 compound treatment 0.263 0.0496 0.71 0.262 0.0517 0.87 1.1155 0.9949 3124711 ChemDiv3_015387 Cc1ccc(C)c(NC(=O)c2nccnc2COC(=O)c3cccc(F)c3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L10 compound treatment 0.253 0.0396 0.57 0.256 0.0457 0.77 0.9431 0.9887 3041902 ChemDiv3_015388 COc1ccc(Nc2nc(no2)c3ccc(OC)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L11 compound treatment 0.262 0.0486 0.69 0.215 0.00475 0.08 0.5475 0.7831 3041943 ChemDiv3_015389 COc1ccc(cc1)c2nnc(o2)C3CCN(CC3)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L12 compound treatment 0.267 0.0536 0.77 0.264 0.0537 0.9 1.1797 0.9967 3041944 ChemDiv3_015390 CCN(Cc1ccccc1)C(=O)CC2Oc3ccccc3NC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L13 compound treatment 0.216 0.00256 0.04 0.249 0.0388 0.65 0.4858 0.7458 3041946 ChemDiv3_015391 O=C(CCc1nc2cccnc2n1Cc3cccs3)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L14 compound treatment 0.244 0.0306 0.44 0.166 -0.0442 -0.74 -0.216 -0.2507 3041948 ChemDiv3_015392 Cc1ccc(cc1C)C(=O)c2cnc3cc4OCOc4cc3c2N5CCC(CC5)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L15 compound treatment 0.276 0.0626 0.89 0.261 0.0508 0.85 1.2351 0.9997 3041949 ChemDiv3_015393 Cn1cc(c(=O)c2cc(F)ccc12)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L16 compound treatment 0.243 0.0296 0.42 0.193 -0.0173 -0.29 0.0943 0.184 3041950 ChemDiv3_015394 CCC(C(=O)Nc1ccccc1OC)n2c(cc3occc23)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L17 compound treatment 0.293 0.0796 1.14 0.234 0.0238 0.4 1.0866 0.9011 3124712 ChemDiv3_015395 CCOC(=O)N1CCN(CC1)C(=O)c2ccc3SCCN(Cc4ccccc4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L18 compound treatment 0.273 0.0596 0.85 0.238 0.0278 0.47 0.9318 0.9596 3041952 ChemDiv3_015396 CC1CCN(CC1)c2nnc(NC(=O)c3csc4CCCCc34)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L19 compound treatment 0.287 0.0736 1.05 0.259 0.0488 0.82 1.3226 0.9923 3124713 ChemDiv3_015397 CN1CCSc2ccc(cc12)C(=O)NCCN3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L20 compound treatment 0.284 0.0706 1.01 0.284 0.0737 1.24 1.589 0.9949 3041955 ChemDiv3_015398 O=C(Cn1ncc2ccccc12)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L21 compound treatment 0.264 0.0506 0.72 0.311 0.101 1.69 1.7071 0.9282 3124714 ChemDiv3_015399 COC(CNC(=O)c1ccc2SCCN(Cc3ccc(Cl)cc3)c2c1)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L22 compound treatment 0.233 0.0196 0.28 0.278 0.0678 1.14 1.0019 0.8556 3124715 ChemDiv3_015400 Cc1ccc(CN2C(=O)CSc3ccc(NC(=O)NCCC4=CCCCC4)cc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L23 mock treatment 0.217 0.00356 0.05 0.26 0.0498 0.84 0.6265 0.7489 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 L24 mock treatment 0.246 0.0326 0.47 0.194 -0.0163 -0.27 0.1365 0.2529 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M01 compound treatment 0.268 0.0546 0.78 0.259 0.0488 0.82 1.1304 0.9997 3041957 ChemDiv3_015401 CN(C(=O)/C=C/c1ccc2OCOc2c1)C3(CCCCC3)C(=O)Nc4c(C)cccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M02 compound treatment 0.251 0.0376 0.54 0.232 0.0217 0.37 0.638 0.9823 3124716 ChemDiv3_015402 OC(CN1CCC(Cc2ccccc2)CC1)CN3CCN(CC3)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M03 compound treatment 0.259 0.0456 0.65 0.246 0.0357 0.6 0.8851 0.9991 3124717 ChemDiv3_015403 COc1ccc(cc1)C2C(C(=O)NC(C)C)c3ccccc3C(=O)N2Cc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M04 compound treatment 0.26 0.0466 0.67 0.283 0.0727 1.22 1.3343 0.9594 3041959 ChemDiv3_015404 COC(=O)c1ccc(NCC(O)Cn2nnnc2c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M05 compound treatment 0.221 0.00756 0.11 0.232 0.0217 0.37 0.3346 0.8789 3124718 ChemDiv3_015405 CCC(=O)NC(c1nc2ccccc2[nH]1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M06 compound treatment 0.236 0.0226 0.32 0.14 -0.0703 -1.18 -0.6055 -0.4953 3041960 ChemDiv3_015406 COC(=O)c1[nH]c2ccccc2c1C(Nc3ccc(cc3)C(=O)O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M07 compound treatment 0.248 0.0346 0.49 0.263 0.0527 0.89 0.9756 0.9621 3124719 ChemDiv3_015407 Cc1ccc2c(c1)sc3ncc(c(=O)n23)S(=O)(=O)c4ccc(F)c(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M08 compound treatment 0.246 0.0326 0.47 0.225 0.0147 0.25 0.5044 0.9563 3041963 ChemDiv3_015408 Clc1cccc(Cc2nnc(o2)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M09 compound treatment 0.316 0.103 1.47 0.223 0.0127 0.21 1.1887 0.8018 3124720 ChemDiv3_015409 COc1ccc(CNC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M10 compound treatment 0.241 0.0276 0.39 0.173 -0.0372 -0.63 -0.1633 -0.221 3041965 ChemDiv3_015410 C(C1CCN(Cc2nnc(o2)c3ccccc3)CC1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M11 compound treatment 0.278 0.0646 0.92 0.242 0.0318 0.53 1.0298 0.9659 3124721 ChemDiv3_015411 CC(=O)Nc1ccc(cc1)c2cc(nc3[nH]nc(c4ccccc4)c23)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M12 compound treatment 0.257 0.0436 0.62 0.199 -0.0113 -0.19 0.3071 0.4717 3041967 ChemDiv3_015412 CCN(Cc1nnc(o1)c2ccccc2C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M13 compound treatment 0.252 0.0386 0.55 0.266 0.0558 0.94 1.0517 0.9682 3124722 ChemDiv3_015413 O=C(N1CCN(CC1)c2ccccc2)c3cc(on3)C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M14 compound treatment 0.278 0.0646 0.92 0.208 -0.00225 -0.04 0.6263 0.6776 3042016 ChemDiv3_015414 CCNc1c(NS(=O)(=O)c2cccc(C#N)c2)c(=O)oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M15 compound treatment 0.224 0.0106 0.15 0.236 0.0257 0.43 0.4124 0.9008 3042017 ChemDiv3_015415 O=C(NCc1cccnc1)C2N(Cc3ccccc3)C(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M16 compound treatment 0.248 0.0346 0.49 0.254 0.0437 0.73 0.8688 0.9815 3042018 ChemDiv3_015416 Cc1ccc(C)c(c1)N2CCN(CC2)C(=O)c3ccc(cc3)N4CCCC4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M17 compound treatment 0.269 0.0556 0.79 0.259 0.0488 0.82 1.1405 0.9999 3042020 ChemDiv3_015417 COc1cc2n(CC(=O)N(CC=C)c3ccccc3)c(=O)n(Cc4ccco4)c(=O)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M18 compound treatment 0.261 0.0476 0.68 0.215 0.00475 0.08 0.5374 0.7846 3042021 ChemDiv3_015418 OC(=O)CCc1nnc2ccc(nn12)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M19 compound treatment 0.236 0.0226 0.32 0.199 -0.0113 -0.19 0.0947 0.2532 3042023 ChemDiv3_015419 Cc1ccc(CNC(=O)NCCN2CCN(CC2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M20 compound treatment 0.212 -0.00144 -0.02 0.22 0.00975 0.16 0.1012 0.6134 3042024 ChemDiv3_015420 CCCC(N1Cc2ccccc2C1=O)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M21 compound treatment 0.227 0.0136 0.19 0.232 0.0217 0.37 0.3953 0.9562 3124723 ChemDiv3_015421 CN1C(C(C(=O)Nc2ccc(F)c(Cl)c2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M22 compound treatment 0.222 0.00856 0.12 0.208 -0.00225 -0.04 0.0599 0.4674 3124724 ChemDiv3_015422 COC(CNC(=O)c1cccc2CN(Cc3cccnc3)C(=O)c21)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M23 mock treatment 0.251 0.0376 0.54 0.198 -0.0123 -0.21 0.2345 0.4077 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 M24 mock treatment 0.215 0.00156 0.02 0.196 -0.0143 -0.24 -0.1533 -0.6383 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N01 compound treatment 0.231 0.0176 0.25 0.231 0.0208 0.35 0.4239 0.9871 3042027 ChemDiv3_015423 COc1ccc(cc1)N2Cc3cccc(C(=O)NCCC4=CCCCC4)c3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N02 compound treatment 0.244 0.0306 0.44 0.242 0.0318 0.53 0.6859 0.9952 3124725 ChemDiv3_015424 Clc1ccc2n(CCCC(=O)N3CCOCC3)nc(c4ccccc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N03 compound treatment 0.225 0.0116 0.17 0.213 0.00275 0.05 0.1496 0.8712 3042029 ChemDiv3_015425 Cc1cc(C(=O)Nc2ccc(Cl)cc2)n(n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N04 compound treatment 0.26 0.0466 0.67 0.256 0.0457 0.77 1.0139 0.9975 3124726 ChemDiv3_015426 Cc1ccc(cc1)S(=O)(=O)c2cnc(SCC(=O)N3CCCc4ccccc34)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N05 compound treatment 0.277 0.0636 0.91 0.253 0.0428 0.72 1.1502 0.9931 3042031 ChemDiv3_015427 O=C(N1CCCC1)c2cnc(nc2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N06 compound treatment 0.273 0.0596 0.85 0.238 0.0278 0.47 0.9318 0.9596 3124727 ChemDiv3_015428 CC(C)CCn1c(=O)n(Cc2cccc(F)c2)c3ncccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N07 compound treatment 0.235 0.0216 0.31 0.23 0.0198 0.33 0.4525 0.9994 3042033 ChemDiv3_015429 CC(C)N(Cc1nc(no1)c2ccccc2)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N08 compound treatment 0.305 0.0916 1.31 0.262 0.0517 0.87 1.5403 0.9801 3124973 ChemDiv3_015430 CCCC(CCC)C(=O)N1CCNc2ccccc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N09 compound treatment 0.264 0.0506 0.72 0.201 -0.00925 -0.16 0.4016 0.5429 3124837 ChemDiv3_015431 Cc1nn2CN(Cc3ccc(Cl)cc3)CNc2c1c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N10 compound treatment 0.293 0.0796 1.14 0.255 0.0447 0.75 1.3358 0.9797 3042035 ChemDiv3_015432 COc1ccc(cc1)c2noc(n2)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N11 compound treatment 0.283 0.0696 0.99 0.251 0.0408 0.68 1.1872 0.9833 3124838 ChemDiv3_015433 COc1ccccc1c2nnc(o2)C3CCN(CC3)C(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N12 compound treatment 0.232 0.0186 0.27 0.229 0.0187 0.31 0.4103 0.9964 3042037 ChemDiv3_015434 CC(C)NC(=O)CC1Oc2ccc(Cl)cc2NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N13 compound treatment 0.213 -4.38E-4 -0.01 0.205 -0.00525 -0.09 -0.0667 -0.7554 3124839 ChemDiv3_015435 CCc1ccc(NC(=O)CCc2nc3cccnc3n2Cc4cccs4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N14 compound treatment 0.209 -0.00444 -0.06 0.164 -0.0462 -0.78 -0.5938 -0.7624 3124840 ChemDiv3_015436 CN1CCN(CC1)c2c(cnc3cc4OCOc4cc23)C(=O)c5ccc(C)c(C)c5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N15 compound treatment 0.256 0.0426 0.61 0.326 0.116 1.94 1.8042 0.8862 3042040 ChemDiv3_015437 CCc1ccc(cc1)S(=O)(=O)c2cn(C)c3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N16 compound treatment 0.086 -0.127 -1.82 0.088 -0.122 -2.05 -2.7398 -0.9983 3042041 ChemDiv3_015438 COC(=O)c1cc2ccsc2n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N17 compound treatment 0.264 0.0506 0.72 0.24 0.0297 0.5 0.8645 0.9836 3042184 ChemDiv3_015439 O=C(N1CCOCC1)c2ccc3SCCN(Cc4ccccc4)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N18 compound treatment 0.253 0.0396 0.57 0.254 0.0437 0.73 0.9194 0.9917 3042099 ChemDiv3_015440 CN1C(=O)CSc2ccc(NC(=O)Nc3ccc(C)cc3)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N19 compound treatment 0.259 0.0456 0.65 0.237 0.0267 0.45 0.7783 0.9835 3042101 ChemDiv3_015441 CCN1CCSc2ccc(cc12)C(=O)NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N20 compound treatment 0.258 0.0446 0.64 0.221 0.0107 0.18 0.5783 0.873 3042102 ChemDiv3_015442 O=C(Cn1ncc2ccccc12)N3CCc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N21 compound treatment 0.221 0.00756 0.11 0.241 0.0308 0.52 0.4414 0.8371 3042103 ChemDiv3_015443 COC(CNC(=O)CC1C(=O)N(Cc2ccccc2)C(C)c3nc4ccccc4n13)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N22 compound treatment 0.223 0.00956 0.14 0.202 -0.00825 -0.14 -0.0012 -0.0061 3042105 ChemDiv3_015444 Clc1cccc(c1)c2cc(NC(=O)Cn3ncc4ccccc34)on2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N23 mock treatment 0.219 0.00556 0.08 0.228 0.0177 0.3 0.2669 0.8656 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 N24 mock treatment 0.197 -0.0164 -0.24 0.223 0.0127 0.21 -0.0149 -0.047 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O01 compound treatment 0.246 0.0326 0.47 0.209 -0.00125 -0.02 0.3145 0.6746 3042106 ChemDiv3_015445 O=C(NC1CCCC1)C2(CCCCC2)N(Cc3cccs3)C(=O)c4cnccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O02 compound treatment 0.225 0.0116 0.17 0.218 0.00775 0.13 0.2089 0.9929 3042108 ChemDiv3_015446 Clc1ccc(OCC(=O)NCCCN2CCN(CC2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O03 compound treatment 0.218 0.00456 0.07 0.216 0.00575 0.1 0.1144 0.9819 3124841 ChemDiv3_015447 COc1ccc2[nH]c3CCN(C)Cc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O04 compound treatment 0.264 0.0506 0.72 0.246 0.0357 0.6 0.9357 0.9957 3042109 ChemDiv3_015448 O=C(NCc1ccccn1)c2nnc(o2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O05 compound treatment 0.25 0.0366 0.52 0.214 0.00375 0.06 0.4143 0.7865 3124842 ChemDiv3_015449 COC(=O)CNc1c(nc2ccccn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O06 compound treatment 0.237 0.0236 0.34 0.176 -0.0343 -0.57 -0.1682 -0.2524 3124843 ChemDiv3_015450 CCOC(=O)CSC(c1c([nH]c2ccccc12)C(=O)OC)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O07 compound treatment 0.259 0.0456 0.65 0.26 0.0498 0.84 1.0513 0.9925 3042112 ChemDiv3_015451 Cc1ccc(CN2CCc3[nH]c(=O)[nH]c(=O)c3C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O08 compound treatment 0.244 0.0306 0.44 0.233 0.0227 0.38 0.5791 0.9977 3124844 ChemDiv3_015452 CCOC(=O)Cc1nnc(o1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O09 compound treatment 0.251 0.0376 0.54 0.213 0.00275 0.05 0.4126 0.765 3042115 ChemDiv3_015453 Cc1ccc(CNC(=O)c2ccc(cc2)N3CCCS3(=O)=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O10 compound treatment 0.229 0.0156 0.22 0.225 0.0147 0.25 0.3325 0.9986 3124845 ChemDiv3_015454 CNc1c(NS(=O)(=O)c2ccc(Cl)cc2)c(=O)oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O11 compound treatment 0.248 0.0346 0.49 0.27 0.0597 1.0 1.0587 0.9469 3124846 ChemDiv3_015455 COc1ccc(cc1OC)c2cc(nc3[nH]nc(c4ccccc4)c23)C(=O)NCCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O12 compound treatment 0.224 0.0106 0.15 0.181 -0.0293 -0.49 -0.2403 -0.4678 3042117 ChemDiv3_015456 Cc1ccccc1c2nnc(CN3CCCC3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O13 compound treatment 0.128 -0.0854 -1.22 0.096 -0.114 -1.92 -2.2201 -0.9763 3042119 ChemDiv3_015457 Cc1ccccc1Nc2c(nc3sccn23)c4ccc(O)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O14 compound treatment 0.206 -0.00744 -0.11 0.211 7.5E-4 0.01 -0.0663 -0.6191 3124847 ChemDiv3_015458 Cc1ccc(CN2CCN(CC(=O)NCc3ccc4OCOc4c3)C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O15 compound treatment 0.229 0.0156 0.22 0.234 0.0238 0.4 0.4393 0.9621 3124848 ChemDiv3_015459 O=C(NCc1cccnc1)C2N(C3CCCC3)C(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O16 compound treatment 0.207 -0.00644 -0.09 0.242 0.0318 0.53 0.3117 0.5764 3042122 ChemDiv3_015460 COc1ccc(cc1)C2NC(=O)c3[nH]nc(c23)c4cccc(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O17 compound treatment 0.233 0.0196 0.28 0.215 0.00475 0.08 0.2542 0.8738 3124849 ChemDiv3_015461 Cc1cccc(NC(=O)NC2CCCCC2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O18 compound treatment 0.231 0.0176 0.25 0.217 0.00675 0.11 0.2577 0.9353 3124850 ChemDiv3_015462 OC(=O)C(CS(=O)(=O)Cc1ccccc1)N2Cc3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O19 compound treatment 0.207 -0.00644 -0.09 0.215 0.00475 0.08 -0.0087 -0.0717 3042124 ChemDiv3_015463 CCc1ccccc1NC(=O)NCCN2CCN(CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O20 compound treatment 0.24 0.0266 0.38 0.21 -2.5E-4 0.0 0.2657 0.6993 3042185 ChemDiv3_015464 CSc1ccc(CCNC(=O)c2cccc3CN(CC4CCCO4)C(=O)c32)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O21 compound treatment 0.206 -0.00744 -0.11 0.208 -0.00225 -0.04 -0.1019 -0.9029 3042187 ChemDiv3_015465 CC1CCCN(C1)C(=O)C2C(N(C)C(=O)c3ccccc23)c4c[nH]c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O22 compound treatment 0.207 -0.00644 -0.09 0.211 7.5E-4 0.01 -0.0562 -0.6048 3042189 ChemDiv3_015466 O=C(N1CCN(Cc2ccccc2)CC1)c3cccc4CN(Cc5cccnc5)C(=O)c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O23 mock treatment 0.2 -0.0134 -0.19 0.207 -0.00325 -0.05 -0.1745 -0.8733 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 O24 mock treatment 0.229 0.0156 0.22 0.209 -0.00125 -0.02 0.1426 0.6376 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P01 compound treatment 0.241 0.0276 0.39 0.241 0.0308 0.52 0.6437 0.9912 3042190 ChemDiv3_015467 FC(F)(F)c1cccc(NC(=O)C2CCC(Cn3c(=O)[nH]c4ccsc4c3=O)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P02 compound treatment 0.198 -0.0154 -0.22 0.194 -0.0163 -0.27 -0.349 -0.9945 3124851 ChemDiv3_015468 CCOC(=O)C1CCN(CC1)C(=O)CCCn2nc(c3ccccc3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P03 compound treatment 0.24 0.0266 0.38 0.237 0.0267 0.45 0.5861 0.9966 3042192 ChemDiv3_015469 CCCNC(=O)C1CCN(CC1)c2cc(C)nc3c(c(C)nn23)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P04 compound treatment 0.234 0.0206 0.29 0.226 0.0158 0.26 0.3949 0.9986 3124852 ChemDiv3_015470 O=C(NCc1cccnc1)c2cccc3sc(nc23)N4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P05 compound treatment 0.281 0.0676 0.97 0.24 0.0297 0.5 1.0364 0.9528 3042194 ChemDiv3_015471 CCCNC(=O)c1cnc(nc1)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P06 compound treatment 0.238 0.0246 0.35 0.252 0.0418 0.7 0.7439 0.949 3124853 ChemDiv3_015472 CN(C1CCCCC1)C(=O)Cn2ncc3COc4ccccc4-c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P07 compound treatment 0.268 0.0546 0.78 0.248 0.0377 0.63 0.9999 0.9947 3042197 ChemDiv3_015473 CC(=O)N1CCc2cc(ccc12)C(O)CN3CCN(CC3)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P08 compound treatment 0.246 0.0326 0.47 0.244 0.0338 0.57 0.7299 0.9953 3124854 ChemDiv3_015474 COc1ccc(cc1)c2noc(n2)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P09 compound treatment 0.268 0.0546 0.78 0.251 0.0408 0.68 1.0355 0.9978 3124855 ChemDiv3_015475 CCOc1ccc(NC(=O)c2ccnc(c2)N3CCC(CC3)C(=O)N4CCOCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P10 compound treatment 0.258 0.0446 0.64 0.252 0.0418 0.7 0.9462 0.9989 3042199 ChemDiv3_015476 CCN1CCCC1CNCc2c(C(=O)O)n(Cc3ccccc3C)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P11 compound treatment 0.261 0.0476 0.68 0.226 0.0158 0.26 0.668 0.9152 3124856 ChemDiv3_015477 COc1ccc(cc1)c2nnc(o2)C3CCN(CC3)C(=O)c4c(F)cccc4F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P12 compound treatment 0.268 0.0546 0.78 0.23 0.0198 0.33 0.7863 0.9273 3124857 ChemDiv3_015478 Cc1ccnc(NC(=O)Cn2ncc3COc4ccc(C)cc4-c32)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P13 compound treatment 0.229 0.0156 0.22 0.25 0.0398 0.67 0.6292 0.8946 3042202 ChemDiv3_015479 CC(C)NC(=O)c1cc2CSc3ccccc3-c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P14 compound treatment 0.252 0.0386 0.55 0.242 0.0318 0.53 0.7668 0.9999 3124858 ChemDiv3_015480 CCN1CCN(CC1)c2c(cnc3ccc(C)cc23)C(=O)c4ccc(C)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P15 compound treatment 0.268 0.0546 0.78 0.251 0.0408 0.68 1.0355 0.9978 3042204 ChemDiv3_015481 CCc1ccc(cc1)S(=O)(=O)c2cn(CC)c3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P16 compound treatment 0.277 0.0636 0.91 0.25 0.0398 0.67 1.1146 0.9884 3124859 ChemDiv3_015482 CC(C)CCNC(=O)C1CCN(CC1)C(=O)c2cc3sccc3n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P17 compound treatment 0.251 0.0376 0.54 0.22 0.00975 0.16 0.4956 0.8825 3042205 ChemDiv3_015483 O=C(N1CCN(CC1)c2ccccn2)c3ccc4SCCN(Cc5ccccc5)c4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P18 compound treatment 0.302 0.0886 1.27 0.264 0.0537 0.9 1.5337 0.9862 3124860 ChemDiv3_015484 CN1C(=O)CSc2ccc(NC(=O)N3CCc4ccccc34)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P19 compound treatment 0.308 0.0946 1.35 0.272 0.0617 1.04 1.6893 0.9914 3124861 ChemDiv3_015485 CCN1CCSc2ccc(cc12)C(=O)Nc3ccc(CC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P20 compound treatment 0.295 0.0816 1.17 0.259 0.0488 0.82 1.4035 0.9849 3042207 ChemDiv3_015486 Clc1ccc(CNC(=O)Cn2ncc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P21 compound treatment 0.251 0.0376 0.54 0.242 0.0318 0.53 0.7567 1.0 3124862 ChemDiv3_015487 Cc1ccc(Cl)cc1N2CCN(CCCNC(=O)Cn3ncc4ccsc4c3=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P22 compound treatment 0.261 0.0476 0.68 0.232 0.0217 0.37 0.7392 0.9574 3042209 ChemDiv3_015488 CCOC(=O)c1nccn1Cc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P23 mock treatment 0.251 0.0376 0.54 0.259 0.0488 0.82 0.9585 0.9792 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2044 P24 mock treatment 0.238 0.0246 0.35 0.198 -0.0123 -0.21 0.103 0.2531 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A01 compound treatment 0.205 -0.00966 -0.14 0.208 -0.00109 -0.02 -0.1106 -0.7941 3042266 ChemDiv3_015489 CCOC(=O)c1nccn1CC(=O)Nc2ccccc2CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A02 compound treatment 0.196 -0.0187 -0.27 0.221 0.0119 0.2 -0.0474 -0.1421 3042268 ChemDiv3_015490 CC1CN(C(=O)N2CCC(CC2)C(=O)O)c3cc(Cl)ccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A03 compound treatment 0.207 -0.00766 -0.11 0.196 -0.0131 -0.22 -0.2328 -0.9483 3042269 ChemDiv3_015491 COc1ccc(cc1)c2n[nH]cc2C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A04 compound treatment 0.18 -0.0347 -0.5 0.211 0.00191 0.03 -0.3279 -0.6601 3042271 ChemDiv3_015492 C(CNc1nc2ccccc2n3nnnc13)CN4CCC(Cc5ccccc5)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A05 compound treatment 0.204 -0.0107 -0.15 0.2 -0.00909 -0.15 -0.2157 -1.0 3042272 ChemDiv3_015493 COc1ccc(CN2C(=O)c3ccccc3CC2(C)C(=O)NC4CCCCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A06 compound treatment 0.217 0.00234 0.03 0.199 -0.0101 -0.17 -0.0961 -0.5564 3042273 ChemDiv3_015494 CC1CCC(CC1)NC(=O)C2CCN(CC2)c3nnc(s3)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A07 compound treatment 0.195 -0.0197 -0.28 0.191 -0.0181 -0.3 -0.4135 -0.9993 3124863 ChemDiv3_015495 O=C(N1CCCCC1)c2nsc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A08 compound treatment 0.193 -0.0217 -0.31 0.2 -0.00909 -0.15 -0.327 -0.9468 3124864 ChemDiv3_015496 COC(=O)c1ccccc1NC(=O)c2ccc3nc(sc3c2)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A09 compound treatment 0.222 0.00734 0.11 0.189 -0.0201 -0.34 -0.1642 -0.4648 3042275 ChemDiv3_015497 O=C(CCC(=O)N1CCc2ccccc2C1)N3CCC(=CC3)c4c[nH]c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A10 compound treatment 0.2 -0.0147 -0.21 0.188 -0.0211 -0.35 -0.3986 -0.9687 3124865 ChemDiv3_015498 COc1ccc(Cl)cc1NC(=O)CN2C(=O)CSc3ncccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A11 compound treatment 0.199 -0.0157 -0.22 0.214 0.00491 0.08 -0.1001 -0.4196 3042277 ChemDiv3_015499 C(Cc1ccccc1)NCc2c[nH]nc2c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A12 compound treatment 0.214 -6.56E-4 -0.01 0.194 -0.0151 -0.25 -0.1858 -0.7328 3124974 ChemDiv3_015500 CCOC(=O)N1CCC(CC1)NC(=O)CCCN2C(=O)CSc3nc(C)cc(C)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A13 compound treatment 0.199 -0.0157 -0.22 0.189 -0.0201 -0.34 -0.3968 -0.9802 3124975 ChemDiv3_015501 O=C(N1CCOCC1)c2ccc(CN3C(=O)CCn4nccc34)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A14 compound treatment 0.193 -0.0217 -0.31 0.213 0.00391 0.07 -0.1727 -0.5454 3042279 ChemDiv3_015502 CCC(Sc1nc2ccncc2[nH]1)C(=O)N(Cc3ccccc3)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A15 compound treatment 0.205 -0.00966 -0.14 0.194 -0.0151 -0.25 -0.2768 -0.9593 3124976 ChemDiv3_015503 Cc1ccc(C)n1c2nnc(s2)N3CCCC(C3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A16 compound treatment 0.202 -0.0127 -0.18 0.181 -0.0281 -0.47 -0.4614 -0.9136 3124977 ChemDiv3_015504 CCN(Cc1ccccc1)C(=O)Cn2cc3CCCCCCc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A17 compound treatment 0.175 -0.0397 -0.57 0.19 -0.0191 -0.32 -0.6277 -0.9635 3042281 ChemDiv3_015505 COc1ccc2c(c1)sc3ncc(C(=O)NCC(C)c4ccccc4)c(=O)n23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A18 compound treatment 0.204 -0.0107 -0.15 0.204 -0.00509 -0.09 -0.1682 -0.9626 3124978 ChemDiv3_015506 CNC(=O)C(C)n1c(C)c2cnn(c3ccccc3)c(=O)c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A19 compound treatment 0.196 -0.0187 -0.27 0.166 -0.0431 -0.72 -0.7001 -0.9082 3042283 ChemDiv3_015507 CCOC(=O)c1oc2ccc3OC4(CCCC4)CC(=O)c3c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A20 compound treatment 0.151 -0.0637 -0.91 0.204 -0.00509 -0.09 -0.7043 -0.7701 3124979 ChemDiv3_015508 OC(=O)c1ccc(s1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A21 compound treatment 0.208 -0.00666 -0.1 0.209 -9.38E-5 0.0 -0.0684 -0.7187 3124980 ChemDiv3_015509 CCCNC(=O)c1ccc(cc1)n2c(C)cc3CCCCc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A22 compound treatment 0.229 0.0143 0.21 0.25 0.0409 0.69 0.6306 0.88 3042285 ChemDiv3_015510 Clc1ccccc1NC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A23 mock treatment 0.188 -0.0267 -0.38 0.203 -0.00609 -0.1 -0.3419 -0.8662 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 A24 mock treatment 0.194 -0.0207 -0.3 0.179 -0.0301 -0.51 -0.5661 -0.9674 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B01 compound treatment 0.214 -6.56E-4 -0.01 0.225 0.0159 0.27 0.1821 0.6818 3124981 ChemDiv3_015511 Cc1ccc(NC(=O)CCS(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B02 compound treatment 0.221 0.00634 0.09 0.214 0.00491 0.08 0.1224 0.9988 3042287 ChemDiv3_015512 O=C(Nc1ccccc1)N2CCn3c2nc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B03 compound treatment 0.221 0.00634 0.09 0.204 -0.00509 -0.09 0.0037 0.0298 3124982 ChemDiv3_015513 CN(Cc1ccccc1)C(=O)CCc2c(C)nc3n(nc(C)c3c2C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B04 compound treatment 0.189 -0.0257 -0.37 0.172 -0.0371 -0.62 -0.6997 -0.9682 3042289 ChemDiv3_015514 C(CSc1nc2ccccc2[nH]1)Oc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B05 compound treatment 0.226 0.0113 0.16 0.216 0.00691 0.12 0.1967 0.9864 3124983 ChemDiv3_015515 CCOc1cc(CCn2cnc3c4cc(C)ccc4[nH]c3c2=O)ccc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B06 compound treatment 0.219 0.00434 0.06 0.204 -0.00509 -0.09 -0.0165 -0.1563 3124984 ChemDiv3_015516 CCCCC1CCC(CC1)C(=O)Nc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B07 compound treatment 0.216 0.00134 0.02 0.189 -0.0201 -0.34 -0.2249 -0.6657 1726214 ChemDiv3_015517 CC(C)N(C(=O)CSc1nc2cc(C)ccc2[nH]1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B08 compound treatment 0.229 0.0143 0.21 0.224 0.0149 0.25 0.322 0.9951 3042346 ChemDiv3_015518 CSc1ncc(Cl)c(n1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B09 compound treatment 0.203 -0.0117 -0.17 0.211 0.00191 0.03 -0.0953 -0.5612 3042348 ChemDiv3_015519 Cc1ccc(OCCCn2cnc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B10 compound treatment 0.22 0.00534 0.08 0.234 0.0249 0.42 0.3496 0.8228 3042349 ChemDiv3_015520 CCCn1c(SCc2nc(no2)c3ccc(OC)cc3)nnc1c4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B11 compound treatment 0.293 0.0783 1.12 0.239 0.0299 0.5 1.1473 0.9344 3042351 ChemDiv3_015521 Cc1ccc(Cn2c(CNC(=O)c3ccccc3)nc4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B12 compound treatment 0.235 0.0203 0.29 0.224 0.0149 0.25 0.3827 0.9972 3042352 ChemDiv3_015522 O=C(CCc1nc(no1)c2ccccc2)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B13 compound treatment 0.215 3.44E-4 0.0 0.212 0.00291 0.05 0.038 0.7745 3042354 ChemDiv3_015523 Brc1ccc(cc1)C(=O)CCC(=O)Nc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B14 compound treatment 0.221 0.00634 0.09 0.186 -0.0231 -0.39 -0.2099 -0.5273 3124985 ChemDiv3_015524 Oc1nc(SCc2ccccc2)nc3[nH]cnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B15 compound treatment 0.214 -6.56E-4 -0.01 0.211 0.00191 0.03 0.016 0.4794 3124986 ChemDiv3_015525 Cc1cc(C)c2c(CC(=O)Nc3sc4CCCc4c3C(=O)NCC5CCCO5)coc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B16 compound treatment 0.207 -0.00766 -0.11 0.184 -0.0251 -0.42 -0.3753 -0.8623 3042356 ChemDiv3_015526 Clc1ccccc1Cn2c(nc3ccccc23)C4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B17 compound treatment 0.215 3.44E-4 0.0 0.207 -0.00209 -0.04 -0.0214 -0.6023 3124987 ChemDiv3_015527 CC(C)N(Cc1cc2ccc(C)cc2nc1O)C(=O)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B18 compound treatment 0.216 0.00134 0.02 0.186 -0.0231 -0.39 -0.2605 -0.6712 1188414 ChemDiv3_015528 CCCc1cc(=O)[nH]c(Nc2ccc(CC)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B19 compound treatment 0.212 -0.00266 -0.04 0.214 0.00491 0.08 0.0314 0.3458 3124988 ChemDiv3_015529 COc1ccc(CNc2nc3[nH]c4CCCc4c(=O)n3n2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B20 compound treatment 0.231 0.0163 0.23 0.222 0.0129 0.22 0.3185 0.9993 1304801 ChemDiv3_015530 Cc1ccc2[nH]c3C(CCCc3c2c1)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B21 compound treatment 0.244 0.0293 0.42 0.242 0.0329 0.55 0.6873 0.9908 3124989 ChemDiv3_015531 COc1ccc(cc1)S(=O)(=O)N2CCC(CC2)n3c(=O)[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B22 compound treatment 0.227 0.0123 0.18 0.232 0.0229 0.38 0.3967 0.9377 1180984 ChemDiv3_015532 CC(=O)OC1(CN2CCC1c3ccccc23)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B23 mock treatment 0.22 0.00534 0.08 0.237 0.0279 0.47 0.3852 0.8118 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 B24 mock treatment 0.219 0.00434 0.06 0.203 -0.00609 -0.1 -0.0284 -0.2372 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C01 compound treatment 0.207 -0.00766 -0.11 0.189 -0.0201 -0.34 -0.3159 -0.8909 3042360 ChemDiv3_015533 CCOC(=O)c1nccn1CC(=O)N(C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C02 compound treatment 0.04 -0.175 -2.5 0.183 -0.0261 -0.44 -2.0762 -0.8186 3124990 ChemDiv3_015534 CC1CN(C(=O)n2ccnc2)c3ccccc3S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C03 compound treatment 0.198 -0.0167 -0.24 0.212 0.00291 0.05 -0.134 -0.5509 3042362 ChemDiv3_015535 COc1ccc(cc1)c2n[nH]cc2C(=O)NCCC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C04 compound treatment 0.04 -0.175 -2.5 0.207 -0.00209 -0.04 -1.7914 -0.717 3124991 ChemDiv3_015536 CCN(c1ccccc1)c2nc3ccccc3n4nnnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C05 compound treatment 0.04 -0.175 -2.5 0.039 -0.17 -2.85 -3.7852 -0.9978 3124992 ChemDiv3_015537 CC1(Cc2ccccc2C(=O)N1C3CCCCC3)C(=O)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C06 compound treatment 0.183 -0.0317 -0.45 0.191 -0.0181 -0.3 -0.5349 -0.9811 3042364 ChemDiv3_015538 CN(Cc1ccccc1)C(=O)C2CCN(CC2)c3nnc(s3)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C07 compound treatment 0.052 -0.163 -2.33 0.202 -0.00709 -0.12 -1.7293 -0.7423 3124993 ChemDiv3_015539 COC(=O)c1cc2sccc2n1C(C)C(=O)Nc3cc(Cl)ccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C08 compound treatment 0.195 -0.0197 -0.28 0.213 0.00391 0.07 -0.1524 -0.5281 3042365 ChemDiv3_015540 Clc1ccccc1CNC(=O)c2ccc3nc(sc3c2)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C09 compound treatment 0.152 -0.0627 -0.9 0.041 -0.168 -2.82 -2.6287 -0.888 3124994 ChemDiv3_015541 CCOc1ccc(CNCc2c[nH]nc2c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C10 compound treatment 0.164 -0.0507 -0.72 0.201 -0.00809 -0.14 -0.6084 -0.8253 3042367 ChemDiv3_015542 Cc1ccc(NC(=O)CN2C(=O)CSc3ncccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C11 compound treatment 0.189 -0.0257 -0.37 0.217 0.00791 0.13 -0.1657 -0.4245 3041320 ChemDiv3_015543 COc1ccccc1c2n[nH]cc2CNC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C12 compound treatment 0.202 -0.0127 -0.18 0.04 -0.169 -2.84 -2.1348 -0.7507 3041237 ChemDiv3_015544 Cc1cccc(CN2C(=O)CSc3nc(C)cc(C)c23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C13 compound treatment 0.041 -0.174 -2.48 0.056 -0.153 -2.57 -3.5733 -0.9999 3041239 ChemDiv3_015545 CNC(=O)C1CCCN(C1)c2nn3c(=O)cc(C)nc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C14 compound treatment 0.04 -0.175 -2.5 0.063 -0.146 -2.45 -3.5004 -1.0 3041240 ChemDiv3_015546 Cc1cc(NC(=O)NC2CN(C3CCCC3)C(=O)C2)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C15 compound treatment 0.041 -0.174 -2.48 0.041 -0.168 -2.82 -3.7514 -0.998 3041241 ChemDiv3_015547 OC(=O)CN1C(=O)CCCc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C16 compound treatment 0.212 -0.00266 -0.04 0.193 -0.0161 -0.27 -0.2179 -0.7987 3041243 ChemDiv3_015548 Cc1ccc(CNC(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C17 compound treatment 0.197 -0.0177 -0.25 0.148 -0.0611 -1.03 -0.9036 -0.8557 3041244 ChemDiv3_015549 Cc1ccc(CN(CC(=O)O)Cc2cn(nc2c3cccs3)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C18 compound treatment 0.197 -0.0177 -0.25 0.04 -0.169 -2.84 -2.1854 -0.767 3041246 ChemDiv3_015550 Cc1n(CCCC(=O)N2CCCCC2)c(C)c3c(=O)n(ncc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C19 compound treatment 0.198 -0.0167 -0.24 0.179 -0.0301 -0.51 -0.5256 -0.9412 3124995 ChemDiv3_015551 Cc1c(oc2ccc3OC4(CCCC4)CC(=O)c3c12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C20 compound treatment 0.041 -0.174 -2.48 0.04 -0.169 -2.84 -3.7632 -0.9978 3041247 ChemDiv3_015552 O=C(N1CCOCC1)c2ccc(s2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C21 compound treatment 0.205 -0.00966 -0.14 0.04 -0.169 -2.84 -2.1045 -0.7406 1621261 ChemDiv3_015553 COC(=O)CN1C(=O)c2cccnc2Oc3ccc(C)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C22 compound treatment 0.175 -0.0397 -0.57 0.159 -0.0501 -0.84 -0.9956 -0.9816 3124996 ChemDiv3_015554 COc1ccc(OC)c(CCNC(=O)CCc2nc3ncccc3c(=O)n2Cc4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C23 mock treatment 0.228 0.0133 0.19 0.177 -0.0321 -0.54 -0.2459 -0.4303 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 C24 mock treatment 0.189 -0.0257 -0.37 0.199 -0.0101 -0.17 -0.3793 -0.9384 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D01 compound treatment 0.2 -0.0147 -0.21 0.2 -0.00909 -0.15 -0.2562 -0.9878 3041250 ChemDiv3_015555 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)CCC(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D02 compound treatment 0.203 -0.0117 -0.17 0.198 -0.0111 -0.19 -0.2496 -0.9985 3124997 ChemDiv3_015556 CCNC(=O)C1CCCN1S(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D03 compound treatment 0.245 0.0303 0.43 0.266 0.0569 0.96 0.9823 0.9363 3041252 ChemDiv3_015557 CCOc1ccc(NC(=O)CCc2c(C)nc3n(nc(C)c3c2C)C(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D04 compound treatment 0.228 0.0133 0.19 0.225 0.0159 0.27 0.3237 0.9865 3124998 ChemDiv3_015558 O=C(NCCSc1nnnn1c2ccccc2)C(c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D05 compound treatment 0.214 -6.56E-4 -0.01 0.217 0.00791 0.13 0.0872 0.6554 3041254 ChemDiv3_015559 COc1cc2[nH]c3c(=O)n(Cc4ccc(Cl)cc4)cnc3c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D06 compound treatment 0.088 -0.127 -1.81 0.089 -0.12 -2.02 -2.7063 -0.9986 3124999 ChemDiv3_015560 COc1ccc(NC(=O)c2nc(ncc2Cl)S(=O)(=O)C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D07 compound treatment 0.179 -0.0357 -0.51 0.157 -0.0521 -0.87 -0.9789 -0.9671 3125000 ChemDiv3_015561 C(Cc1ccccc1)SCc2nc3ccccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D08 compound treatment 0.25 0.0353 0.51 0.226 0.0169 0.28 0.5581 0.9627 3041257 ChemDiv3_015562 CSc1ncc(Cl)c(n1)C(=O)NCCc2ccc(cc2)S(=O)(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D09 compound treatment 0.26 0.0453 0.65 0.242 0.0329 0.55 0.8492 0.9968 3125248 ChemDiv3_015563 COCc1nc2ccccc2n1CC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D10 compound treatment 0.243 0.0283 0.41 0.24 0.0309 0.52 0.6535 0.9926 3125109 ChemDiv3_015564 CCn1c(SCc2nc(no2)c3cccs3)nnc1c4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D11 compound treatment 0.329 0.114 1.64 0.272 0.0629 1.06 1.9031 0.9776 3041259 ChemDiv3_015565 Clc1ccc(Cn2c(CNC(=O)c3ccccc3)nc4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D12 compound treatment 0.26 0.0453 0.65 0.205 -0.00409 -0.07 0.41 0.6287 3125110 ChemDiv3_015566 CN(C)C(=O)CCc1nc(no1)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D13 compound treatment 0.262 0.0473 0.68 0.218 0.00891 0.15 0.5845 0.8429 3041260 ChemDiv3_015567 CC1=NCCNC2=C1C(N(C2=O)c3ccccc3)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D14 compound treatment 0.258 0.0433 0.62 0.23 0.0209 0.35 0.6865 0.9637 3125111 ChemDiv3_015568 Cc1nnc(SCC(=O)O)nc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D15 compound treatment 0.217 0.00234 0.03 0.212 0.00291 0.05 0.0582 0.9833 3125112 ChemDiv3_015569 CCOC(=O)c1cc(NC(=O)Nc2ccc(C)cc2C)c(C)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D16 compound treatment 0.192 -0.0227 -0.32 0.191 -0.0181 -0.3 -0.4439 -0.9995 3041262 ChemDiv3_015570 Cc1cccc(OCCn2c(nc3ccccc23)C4CCCO4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D17 compound treatment 0.278 0.0633 0.91 0.253 0.0439 0.74 1.1618 0.9947 3041321 ChemDiv3_015571 COc1ccc2nc(O)c(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D18 compound treatment 0.25 0.0353 0.51 0.262 0.0529 0.89 0.9854 0.9643 3041323 ChemDiv3_015572 CCOc1ccc(Nc2cnnc(Nc3ccc(OCC)cc3)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D19 compound treatment 0.237 0.0223 0.32 0.232 0.0229 0.38 0.4978 0.9958 3041325 ChemDiv3_015573 Cc1cc(C)n2nc(Cc3ccccc3)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D20 compound treatment 0.213 -0.00166 -0.02 0.249 0.0399 0.67 0.4569 0.6817 1640163 ChemDiv3_015574 CNC1CCCc2c1n(C)c3ccc(Cl)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D21 compound treatment 0.228 0.0133 0.19 0.225 0.0159 0.27 0.3237 0.9865 3041327 ChemDiv3_015575 Fc1ccc(cc1)c2ccc(=O)[nH]n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D22 compound treatment 0.233 0.0183 0.26 0.191 -0.0181 -0.3 -0.0292 -0.0728 1568202 ChemDiv3_015576 Cc1ccc(cc1C)C(O)(C2CN3CCC2CC3)c4ccc(C)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D23 mock treatment 0.246 0.0313 0.45 0.226 0.0169 0.28 0.5177 0.9757 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 D24 mock treatment 0.216 0.00134 0.02 0.213 0.00391 0.07 0.06 0.8775 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E01 compound treatment 0.229 0.0143 0.21 0.205 -0.00409 -0.07 0.0965 0.446 3125113 ChemDiv3_015577 Clc1ccccc1CNC(=O)CCCN2C(=O)c3ccccc3Sc4ncccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E02 compound treatment 0.231 0.0163 0.23 0.213 0.00391 0.07 0.2117 0.8718 3041329 ChemDiv3_015578 COc1cccc(CNC(=O)c2ccc(cc2)N3CCCC3=O)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E03 compound treatment 0.199 -0.0157 -0.22 0.204 -0.00509 -0.09 -0.2188 -0.9128 3125114 ChemDiv3_015579 CC(NC(=O)Nc1cccc(C)c1C)c2c(C)c(C)sc2n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E04 compound treatment 0.211 -0.00366 -0.05 0.197 -0.0121 -0.2 -0.1805 -0.8612 3041331 ChemDiv3_015580 O=C1CCCN1CCCNc2nc3ccccc3n4nnnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E05 compound treatment 0.233 0.0183 0.26 0.213 0.00391 0.07 0.2319 0.8574 3125115 ChemDiv3_015581 CC(C)N1CCC2(CC1)NC(=O)c3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E06 compound treatment 0.219 0.00434 0.06 0.204 -0.00509 -0.09 -0.0165 -0.1563 3125116 ChemDiv3_015582 O=C(C1CCN(CC1)c2nnc(s2)n3cccc3)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E07 compound treatment 0.18 -0.0347 -0.5 0.239 0.0299 0.5 0.0044 0.0062 3041333 ChemDiv3_015583 COC(=O)c1cc2sccc2n1C(C)C(=O)N(C)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E08 compound treatment 0.203 -0.0117 -0.17 0.216 0.00691 0.12 -0.0359 -0.1769 3125117 ChemDiv3_015584 COc1cc(OC)c(NC(=O)c2ccc3nc(sc3c2)N4CCOCC4)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E09 compound treatment 0.185 -0.0297 -0.42 0.217 0.00791 0.13 -0.2061 -0.4637 3041335 ChemDiv3_015585 Cc1oc(nc1CSc2ccc(Cl)cc2)c3ccc(cc3)C(=O)NCCN4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E10 compound treatment 0.182 -0.0327 -0.47 0.173 -0.0361 -0.61 -0.7587 -0.9917 3125118 ChemDiv3_015586 Cc1ccc(C)c(c1)N2CCN(CCCNC(=O)CN3C(=O)CSc4ncccc34)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E11 compound treatment 0.208 -0.00666 -0.1 0.188 -0.0211 -0.35 -0.3177 -0.8665 3125119 ChemDiv3_015587 COc1ccccc1c2n[nH]cc2CNCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E12 compound treatment 0.254 0.0393 0.56 0.207 -0.00209 -0.04 0.3731 0.6617 3041337 ChemDiv3_015588 CN(C(=O)Cn1c(SCc2ccc(C)cc2)nc3ccncc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E13 compound treatment 0.22 0.00534 0.08 0.252 0.0429 0.72 0.5633 0.7778 3125120 ChemDiv3_015589 CCOC(=O)C1CCN(CC1)c2nnc(s2)N3C(=O)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E14 compound treatment 0.23 0.0153 0.22 0.206 -0.00309 -0.05 0.1185 0.5253 3125121 ChemDiv3_015590 CCc1cccc(NC(=O)NC2CN(C3CCCC3)C(=O)C2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E15 compound treatment 0.233 0.0183 0.26 0.244 0.0349 0.59 0.5998 0.9344 3041339 ChemDiv3_015591 Cc1ccc(cc1)c2cn3nc(sc3n2)N4CCCC(C4)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E16 compound treatment 0.223 0.00834 0.12 0.232 0.0229 0.38 0.3562 0.885 3125122 ChemDiv3_015592 Cc1cc(=O)n2nc(sc2n1)N3CCCC(C3)C(=O)N4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E17 compound treatment 0.227 0.0123 0.18 0.186 -0.0231 -0.39 -0.1492 -0.3504 3125123 ChemDiv3_015593 O=C(NCCCN1CCCC1=O)c2ccc(Cn3c(SCc4ccccc4)nc5ccncc35)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E18 compound treatment 0.226 0.0113 0.16 0.2 -0.00909 -0.15 0.0068 0.0306 3041341 ChemDiv3_015594 CCOC(=O)C1CCN(CC1)C(=O)Cn2ncc3c(C)n(Cc4ccc(Cl)cc4)c(C)c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E19 compound treatment 0.205 -0.00966 -0.14 0.205 -0.00409 -0.07 -0.1463 -0.948 3041343 ChemDiv3_015595 Cc1c(oc2ccc3OC(C)(C)CC(=O)c3c12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E20 compound treatment 0.202 -0.0127 -0.18 0.193 -0.0161 -0.27 -0.319 -0.9811 3125124 ChemDiv3_015596 COc1ccccc1NC(=O)c2ccc(s2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E21 compound treatment 0.202 -0.0127 -0.18 0.207 -0.00209 -0.04 -0.1529 -0.8289 3041406 ChemDiv3_015597 O=C(NC1CC1)Nc2ccc3Sc4ccccc4C(=O)N(Cc5ccccc5)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E22 compound treatment 0.198 -0.0167 -0.24 0.231 0.0219 0.37 0.0915 0.2089 3125125 ChemDiv3_015598 CC1CCN(CC1)C(=O)c2cc3CSc4cc(Cl)ccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E23 mock treatment 0.199 -0.0157 -0.22 0.181 -0.0281 -0.47 -0.4918 -0.9421 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 E24 mock treatment 0.219 0.00434 0.06 0.196 -0.0131 -0.22 -0.1115 -0.4881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F01 compound treatment 0.195 -0.0197 -0.28 0.191 -0.0181 -0.3 -0.4135 -0.9993 3041408 ChemDiv3_015599 CCCN(CCC)C(=O)CCc1c(C)nc2n(nc(C)c2c1C)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F02 compound treatment 0.199 -0.0157 -0.22 0.215 0.00591 0.1 -0.0883 -0.3604 3125126 ChemDiv3_015600 CCOC(=O)c1oc2ccccc2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F03 compound treatment 0.195 -0.0197 -0.28 0.207 -0.00209 -0.04 -0.2237 -0.7893 3125127 ChemDiv3_015601 CCN1Cc2cccc(C(=O)Nc3ccc(CC)cc3)c2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F04 compound treatment 0.256 0.0413 0.59 0.206 -0.00309 -0.05 0.3814 0.6425 3041263 ChemDiv3_015602 C(c1nc2c3cnn(Cc4ccccc4)c3ncn2n1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F05 compound treatment 0.214 -6.56E-4 -0.01 0.206 -0.00309 -0.05 -0.0434 -0.8216 3041265 ChemDiv3_015603 CC/1=NN(C(=O)\C1=C\c2cn(CC(O)CN3CCCCC3)c4ccccc24)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F06 compound treatment 0.062 -0.153 -2.18 0.059 -0.15 -2.52 -3.3253 -0.9975 3041267 ChemDiv3_015604 COc1ccc(CCNC(=O)c2nc(ncc2Cl)S(=O)(=O)C)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F07 compound treatment 0.22 0.00534 0.08 0.219 0.00991 0.17 0.1716 0.9378 3041268 ChemDiv3_015605 CC(C)C(=O)NCCCc1nc2ccccc2n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F08 compound treatment 0.231 0.0163 0.23 0.237 0.0279 0.47 0.4965 0.9485 3041270 ChemDiv3_015606 CCCSc1ncc(Cl)c(n1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F09 compound treatment 0.245 0.0303 0.43 0.266 0.0569 0.96 0.9823 0.9363 3041271 ChemDiv3_015607 COCc1nc2ccccc2n1C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F10 compound treatment 0.219 0.00434 0.06 0.261 0.0519 0.87 0.66 0.7556 3041273 ChemDiv3_015608 Cn1c(SCc2nc(no2)c3cccs3)nnc1c4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F11 compound treatment 0.266 0.0513 0.73 0.236 0.0269 0.45 0.8386 0.9727 3125128 ChemDiv3_015609 CCC(=O)NCCCc1nc2ccccc2n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F12 compound treatment 0.285 0.0703 1.01 0.239 0.0299 0.5 1.0664 0.9484 3041275 ChemDiv3_015610 CCN(CC)C(=O)CCc1nc(no1)c2cccc(OC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F13 compound treatment 0.238 0.0233 0.33 0.253 0.0439 0.74 0.7572 0.9359 3125129 ChemDiv3_015611 COC(=O)c1cc(c2cccc(OC)c2)c3c(=O)[nH]c(=O)n(C)c3n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F14 compound treatment 0.229 0.0143 0.21 0.233 0.0239 0.4 0.4288 0.9515 3125130 ChemDiv3_015612 COCCN1CCn2c(C1)nc3cc(Nc4nnc(C)c5ccccc45)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F15 compound treatment 0.247 0.0323 0.46 0.255 0.0459 0.77 0.872 0.9702 3041277 ChemDiv3_015613 CCOC(=O)c1c(C)[nH]c(NC(=O)Nc2nnc(CC)s2)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F16 compound treatment 0.25 0.0353 0.51 0.196 -0.0131 -0.22 0.2021 0.3666 3125131 ChemDiv3_015614 C(N1CCCc2ccccc12)c3nnc(o3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F17 compound treatment 0.231 0.0163 0.23 0.226 0.0169 0.28 0.3659 0.9954 3041279 ChemDiv3_015615 CCCCN(Cc1cc2cc(OC)ccc2nc1O)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F18 compound treatment 0.232 0.0173 0.25 0.259 0.0499 0.84 0.7677 0.8788 1604125 ChemDiv3_015616 OC(c1ccccc1)c2ccc3n4CCNC5CCCc(c54)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F19 compound treatment 0.248 0.0333 0.48 0.249 0.0399 0.67 0.8109 0.9862 3041281 ChemDiv3_015617 COC(=O)Cc1c(C)[nH]c2ncnn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F20 compound treatment 0.211 -0.00366 -0.05 0.241 0.0319 0.54 0.3417 0.635 3125132 ChemDiv3_015618 CCN(CC)CCNC1=NCCn2c1cc3cc(OC)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F21 compound treatment 0.234 0.0193 0.28 0.22 0.0109 0.18 0.3251 0.9799 3041283 ChemDiv3_015619 O=S(=O)(N1CCC(CC1)N2CCCCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F22 compound treatment 0.218 0.00334 0.05 0.223 0.0139 0.23 0.1989 0.8347 3125133 ChemDiv3_015620 OC1C(Cc2ccccc2)N3CCC1c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F23 mock treatment 0.237 0.0223 0.32 0.201 -0.00809 -0.14 0.1299 0.3742 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 F24 mock treatment 0.214 -6.56E-4 -0.01 0.219 0.00991 0.17 0.1109 0.6661 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G01 compound treatment 0.205 -0.00966 -0.14 0.202 -0.00709 -0.12 -0.1819 -0.9973 3125134 ChemDiv3_015621 O=C(CCN1C(=O)c2ccccc2Sc3ncccc13)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G02 compound treatment 0.203 -0.0117 -0.17 0.197 -0.0121 -0.2 -0.2614 -0.9952 3041285 ChemDiv3_015622 CCOC(=O)Cn1c(cc2ccccc12)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G03 compound treatment 0.228 0.0133 0.19 0.224 0.0149 0.25 0.3119 0.9911 3125135 ChemDiv3_015623 Cc1nn(CCCC(=O)NCCc2ccccc2)c(=O)c3nccn13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G04 compound treatment 0.258 0.0433 0.62 0.251 0.0419 0.7 0.9357 0.998 3041287 ChemDiv3_015624 O=S(=O)(N1CCOCC1)c2ccc(Nc3nc4ccccc4n5nnnc35)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G05 compound treatment 0.202 -0.0127 -0.18 0.233 0.0239 0.4 0.1557 0.3537 3125136 ChemDiv3_015625 COc1ccccc1NC(=O)Nc2nnc(s2)N3CC(C)CC(C)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G06 compound treatment 0.286 0.0713 1.02 0.216 0.00691 0.12 0.8036 0.7824 3125249 ChemDiv3_015626 CCc1ccccc1NC(=O)C2CCCN(C2)c3nnc(s3)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G07 compound treatment 0.212 -0.00266 -0.04 0.177 -0.0321 -0.54 -0.4078 -0.7551 3041344 ChemDiv3_015627 COC(=O)c1cc2sccc2n1C(C)C(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G08 compound treatment 0.286 0.0713 1.02 0.271 0.0619 1.04 1.4563 1.0 3041346 ChemDiv3_015628 Cc1cc(NC(=O)c2ccc3nc(sc3c2)N4CCOCC4)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G09 compound treatment 0.24 0.0253 0.36 0.248 0.0389 0.65 0.7181 0.9614 3041347 ChemDiv3_015629 C(NCc1c[nH]nc1c2ccccc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G10 compound treatment 0.234 0.0193 0.28 0.252 0.0429 0.72 0.7049 0.9137 3041349 ChemDiv3_015630 O=C(CCCN1C(=O)CSc2ncccc12)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G11 compound treatment 0.288 0.0733 1.05 0.3 0.0909 1.53 1.8207 0.9833 3041351 ChemDiv3_015631 CCc1ccc(NC(=O)N2CCc3cc(ccc23)S(=O)(=O)N4CCC(C)CC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G12 compound treatment 0.216 0.00134 0.02 0.267 0.0579 0.97 0.7008 0.7209 3041352 ChemDiv3_015632 CN(C(=O)Cn1c(SCc2ccccc2F)nc3ccncc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G13 compound treatment 0.263 0.0483 0.69 0.278 0.0689 1.16 1.3067 0.9698 3125250 ChemDiv3_015633 CCOc1ccccc1CNC(=O)c2ccc3SCCN(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G14 compound treatment 0.253 0.0383 0.55 0.193 -0.0161 -0.27 0.1968 0.3219 3125251 ChemDiv3_015634 COc1cccc(Cn2c(SCc3ccc(cc3)C(=O)NCc4ccccn4)nc5ccncc25)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G15 compound treatment 0.256 0.0413 0.59 0.252 0.0429 0.72 0.9274 0.9952 3041354 ChemDiv3_015635 COC(=O)c1cnc2sc3ccccc3n2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G16 compound treatment 0.251 0.0363 0.52 0.218 0.00891 0.15 0.4733 0.875 3041355 ChemDiv3_015636 Cc1cc(=O)n2nc(sc2n1)N3CCCC3C(=O)Nc4cccc(F)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G17 compound treatment 0.261 0.0463 0.66 0.247 0.0379 0.64 0.9186 0.9998 3125252 ChemDiv3_015637 OC(=O)c1ccc(Cn2c(SCc3ccccc3F)nc4ccncc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G18 compound treatment 0.234 0.0193 0.28 0.228 0.0189 0.32 0.42 0.9977 3125253 ChemDiv3_015638 Cc1n(Cc2ccc(Cl)cc2)c(C)c3c(=O)n(CC(=O)N4CCc5ccccc45)ncc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G19 compound treatment 0.232 0.0173 0.25 0.204 -0.00509 -0.09 0.115 0.4381 3041357 ChemDiv3_015639 CC1(C)Oc2ccc(OCC(=O)O)cc2C=C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G20 compound treatment 0.208 -0.00666 -0.1 0.201 -0.00809 -0.14 -0.1634 -0.9849 3125254 ChemDiv3_015640 Cc1nc2nc(CNC(=O)OC(C)(C)C)nn2c(C)c1CCC(=O)Nc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G21 compound treatment 0.12 -0.0947 -1.35 0.108 -0.101 -1.7 -2.1572 -0.9937 3041359 ChemDiv3_015641 CCOC(=O)c1cc(C)n(c1C)c2ccc(C)c(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G22 compound treatment 0.189 -0.0257 -0.37 0.196 -0.0131 -0.22 -0.4149 -0.9699 3041361 ChemDiv3_015642 CCN(Cc1ccccc1)C(=O)c2cc3CSc4cc(Cl)ccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G23 mock treatment 0.185 -0.0297 -0.42 0.18 -0.0291 -0.49 -0.6452 -0.9975 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 G24 mock treatment 0.2 -0.0147 -0.21 0.157 -0.0521 -0.87 -0.7665 -0.8525 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H01 compound treatment 0.205 -0.00966 -0.14 0.211 0.00191 0.03 -0.075 -0.5293 3125255 ChemDiv3_015643 COc1cccc(c1)N(Cc2ccc(C)cc2)C3=NC4CS(=O)(=O)CC4S3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H02 compound treatment 0.22 0.00534 0.08 0.2 -0.00909 -0.15 -0.0539 -0.3156 3125256 ChemDiv3_015644 COc1ccc(NC(=O)N2CCc3cc(OC)c(OC)cc3C2c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H03 compound treatment 0.212 -0.00266 -0.04 0.198 -0.0111 -0.19 -0.1585 -0.8342 3041363 ChemDiv3_015645 CCN1Cc2cccc(CNc3ccc(CC)cc3)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H04 compound treatment 0.27 0.0553 0.79 0.218 0.00891 0.15 0.6655 0.826 3125257 ChemDiv3_015646 O=C(CCC1CCCC1)Nc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H05 compound treatment 0.197 -0.0177 -0.25 0.223 0.0139 0.23 -0.0135 -0.0394 3041365 ChemDiv3_015647 CCc1ccccc1N2CC(CC2=O)c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H06 compound treatment 0.058 -0.157 -2.24 0.056 -0.153 -2.57 -3.4014 -0.9977 3125258 ChemDiv3_015648 CC(C)c1ccc(CN(C2CCS(=O)(=O)C2)C(=O)c3nc(ncc3Cl)S(=O)(=O)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H07 compound treatment 0.186 -0.0287 -0.41 0.166 -0.0431 -0.72 -0.8013 -0.9638 3041367 ChemDiv3_015649 CSc1nc2ccccc2n1Cc3ccc(cc3)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H08 compound treatment 0.282 0.0673 0.96 0.248 0.0389 0.65 1.1429 0.9821 3125259 ChemDiv3_015650 CCCSc1ncc(Cl)c(n1)C(=O)Nc2nc(C)c(s2)C(=O)OCC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H09 compound treatment 0.257 0.0423 0.61 0.227 0.0179 0.3 0.6408 0.9477 3041369 ChemDiv3_015651 CCCCn1c(COC)nc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H10 compound treatment 0.212 -0.00266 -0.04 0.181 -0.0281 -0.47 -0.3603 -0.7616 3125260 ChemDiv3_015652 Cc1nnc(SCc2nc(no2)c3ccc(Cl)cc3)n1c4ccc(C)c(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H11 compound treatment 0.263 0.0483 0.69 0.253 0.0439 0.74 1.01 0.9995 3041371 ChemDiv3_015653 Clc1ccc(cc1)C(=O)Cn2cnc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H12 compound treatment 0.242 0.0273 0.39 0.258 0.0489 0.82 0.857 0.9425 3041410 ChemDiv3_015654 CNC(=O)CCc1nc(no1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H13 compound treatment 0.28 0.0653 0.93 0.238 0.0289 0.49 1.004 0.9534 3041411 ChemDiv3_015655 Clc1ccc(cc1)c2ncnc3c(C#N)c4ccccn4c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H14 compound treatment 0.219 0.00434 0.06 0.195 -0.0141 -0.24 -0.1233 -0.5043 3041413 ChemDiv3_015656 CC(=O)NCCc1nc2cc(NC(=O)C)ccc2n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H15 compound treatment 0.211 -0.00366 -0.05 0.252 0.0429 0.72 0.4722 0.654 3041414 ChemDiv3_015657 CCCNC(=O)Nc1[nH]c(C)c(C(=O)OCC)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H16 compound treatment 0.3 0.0853 1.22 0.27 0.0609 1.02 1.586 0.9961 3041416 ChemDiv3_015658 O=c1oc2ccccc2n1Cc3nnc(o3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H17 compound treatment 0.277 0.0623 0.89 0.287 0.0779 1.31 1.5552 0.9826 3041417 ChemDiv3_015659 CCCCN(Cc1cc2cc(OC)ccc2nc1O)C(=O)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H18 compound treatment 0.208 -0.00666 -0.1 0.206 -0.00309 -0.05 -0.104 -0.9594 3041419 ChemDiv3_015660 COc1ccc2n3CCN=C4N(C)CCc(c43)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H19 compound treatment 0.263 0.0483 0.69 0.227 0.0179 0.3 0.7015 0.9304 3041420 ChemDiv3_015661 O=C(Nc1ccc2n3CCN(Cc3nc2c1)c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H20 compound treatment 0.264 0.0493 0.71 0.224 0.0149 0.25 0.676 0.9027 3041422 ChemDiv3_015662 COc1ccc2n3CCN4CCN=C4c3cc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H21 compound treatment 0.27 0.0553 0.79 0.204 -0.00509 -0.09 0.4993 0.6271 3125261 ChemDiv3_015663 Cc1[nH]c2ccc(CNC(=O)Nc3ccc(F)cc3F)cc2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H22 compound treatment 0.211 -0.00366 -0.05 0.231 0.0219 0.37 0.223 0.6005 3125262 ChemDiv3_015664 Clc1ccccc1OCC(=O)N(C2CN3CCC2CC3)c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H23 mock treatment 0.208 -0.00666 -0.1 0.216 0.00691 0.12 0.0146 0.0976 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 H24 mock treatment 0.173 -0.0417 -0.6 0.155 -0.0541 -0.91 -1.0633 -0.9791 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I01 compound treatment 0.21 -0.00466 -0.07 0.208 -0.00109 -0.02 -0.0601 -0.8696 3041425 ChemDiv3_015665 COC(=O)c1cc2sccc2n1CC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I02 compound treatment 0.204 -0.0107 -0.15 0.199 -0.0101 -0.17 -0.2276 -0.9986 3125263 ChemDiv3_015666 COc1ccc(cc1)c2noc(n2)N(C)CC(=O)N3CCN(CC3)c4ccccc4OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I03 compound treatment 0.205 -0.00966 -0.14 0.221 0.0119 0.2 0.0436 0.1796 3041427 ChemDiv3_015667 Cc1nn(CCCC(=O)NC2CCCC2)c(=O)c3nccn13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I04 compound treatment 0.246 0.0313 0.45 0.245 0.0359 0.6 0.7432 0.9894 3125264 ChemDiv3_015668 C(CC1=CCCCC1)Nc2nc3ccccc3n4nnnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I05 compound treatment 0.253 0.0383 0.55 0.223 0.0139 0.23 0.5529 0.9275 3125265 ChemDiv3_015669 COc1ccccc1NC(=O)Nc2nnc(s2)N3CCCCC3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I06 compound treatment 0.227 0.0123 0.18 0.191 -0.0181 -0.3 -0.0899 -0.2559 3041429 ChemDiv3_015670 O=C(NCCc1ccccc1)C2CCCN(C2)c3nnc(s3)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I07 compound treatment 0.276 0.0613 0.88 0.184 -0.0251 -0.42 0.3226 0.3315 3125266 ChemDiv3_015671 COC(=O)c1cc2sccc2n1C(C)C(=O)Nc3ccccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I08 compound treatment 0.255 0.0403 0.58 0.228 0.0189 0.32 0.6324 0.9603 3041432 ChemDiv3_015672 O=C(N1CCCC1)c2ccc3nc(sc3c2)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I09 compound treatment 0.261 0.0463 0.66 0.219 0.00991 0.17 0.5863 0.8579 3125267 ChemDiv3_015673 Fc1cccc(CNCc2c[nH]nc2c3ccc(Br)cc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I10 compound treatment 0.229 0.0143 0.21 0.195 -0.0141 -0.24 -0.0222 -0.0709 3041434 ChemDiv3_015674 O=C(CCCN1C(=O)CSc2ncccc12)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I11 compound treatment 0.197 -0.0177 -0.25 0.196 -0.0131 -0.22 -0.334 -0.9976 3125268 ChemDiv3_015675 COc1ccccc1c2n[nH]cc2CNCc3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I12 compound treatment 0.237 0.0223 0.32 0.238 0.0289 0.49 0.5691 0.9795 3125269 ChemDiv3_015676 CCC1CCCCN1C(=O)Cn2c(SCc3cccc(Cl)c3)nc4ccncc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I13 compound treatment 0.233 0.0183 0.26 0.185 -0.0241 -0.4 -0.1004 -0.2083 3041471 ChemDiv3_015677 COc1ccc(cc1)c2cn3nc(sc3n2)N4CCC(CC4)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I14 compound treatment 0.195 -0.0197 -0.28 0.166 -0.0431 -0.72 -0.7102 -0.9153 3041473 ChemDiv3_015678 CN(Cc1ccccc1)C(=O)c2ccc(CSc3nc4ccncc4n3Cc5ccccc5)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I15 compound treatment 0.229 0.0143 0.21 0.191 -0.0181 -0.3 -0.0697 -0.1901 3041474 ChemDiv3_015679 Cn1c(SCc2ccc(F)cc2)nc3ccc(cc13)C(=O)N4CCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I16 compound treatment 0.223 0.00834 0.12 0.199 -0.0101 -0.17 -0.0354 -0.1708 3041475 ChemDiv3_015680 COc1ccccc1CNC(=O)C2CCCN2c3nn4c(=O)cc(C)nc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I17 compound treatment 0.222 0.00734 0.11 0.257 0.0479 0.8 0.6428 0.7927 3041477 ChemDiv3_015681 CC1=C(c2ccc(C)cc2)S(=O)(=O)N(CC(=O)N3CCN(CC3)c4ccccn4)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I18 compound treatment 0.213 -0.00166 -0.02 0.234 0.0249 0.42 0.2788 0.666 3125270 ChemDiv3_015682 Cc1n(Cc2ccc(Cl)cc2)c(C)c3c(=O)n(CC(=O)NC4CCCc5ccccc45)ncc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I19 compound treatment 0.234 0.0193 0.28 0.213 0.00391 0.07 0.242 0.8511 3041478 ChemDiv3_015683 CCOC(=O)C1=CNc2ccccc2S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I20 compound treatment 0.23 0.0153 0.22 0.203 -0.00609 -0.1 0.0829 0.3422 3041480 ChemDiv3_015684 COc1ccc(OC)c(CNC(=O)CN2Cc3ccccc3C2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I21 compound treatment 0.166 -0.0487 -0.7 0.155 -0.0541 -0.91 -1.1341 -0.9914 3125271 ChemDiv3_015685 COC(=O)c1ccc(c2ccco2)n1CC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I22 compound treatment 0.193 -0.0217 -0.31 0.191 -0.0181 -0.3 -0.4338 -1.0 3125272 ChemDiv3_015686 CC1CCCCN1CCCNC(=O)c2cc3CSc4cc(Cl)ccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I23 mock treatment 0.194 -0.0207 -0.3 0.185 -0.0241 -0.4 -0.4949 -0.9881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 I24 mock treatment 0.206 -0.00866 -0.12 0.209 -9.38E-5 0.0 -0.0887 -0.716 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J01 compound treatment 0.208 -0.00666 -0.1 0.208 -0.00109 -0.02 -0.0803 -0.8282 3041482 ChemDiv3_015687 Cc1cccc(NC(=O)CN(C2=NC3CS(=O)(=O)CC3S2)c4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J02 compound treatment 0.211 -0.00366 -0.05 0.209 -9.38E-5 0.0 -0.0381 -0.7281 3125273 ChemDiv3_015688 O=C(NCCSc1nnnn1c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J03 compound treatment 0.194 -0.0207 -0.3 0.2 -0.00909 -0.15 -0.3168 -0.9528 3041484 ChemDiv3_015689 CCN1Cc2cccc(CNc3cc(C)cc(C)c3)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J04 compound treatment 0.211 -0.00366 -0.05 0.222 0.0129 0.22 0.1162 0.5214 3125274 ChemDiv3_015690 O=C(CC1CCCC1)Nc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J05 compound treatment 0.251 0.0363 0.52 0.235 0.0259 0.43 0.675 0.9961 1201997 ChemDiv3_015691 O=C(NCCc1nc2ccccc2[nH]1)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J06 compound treatment 0.246 0.0313 0.45 0.219 0.00991 0.17 0.4346 0.9089 3125275 ChemDiv3_015692 CSc1ncc(Cl)c(n1)C(=O)Nc2cc(C)ccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J07 compound treatment 0.125 -0.0897 -1.28 0.079 -0.13 -2.18 -2.4508 -0.9678 3125516 ChemDiv3_015693 COc1ccc(Cc2nc3ccccc3n2Cc4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J08 compound treatment 0.273 0.0583 0.83 0.28 0.0709 1.19 1.4316 0.9849 3041488 ChemDiv3_015694 CCc1c(C)nc(SCC(=O)N2CCN(CC2)c3ccccc3)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J09 compound treatment 0.062 -0.153 -2.18 0.12 -0.0891 -1.5 -2.6014 -0.9829 3125388 ChemDiv3_015695 CCC(C)Cn1c(Cc2ccc(OC)cc2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J10 compound treatment 0.249 0.0343 0.49 0.277 0.0679 1.14 1.1533 0.9292 3125389 ChemDiv3_015696 COc1ccc(cc1)c2noc(CSc3nnc(C)n3c4ccc(Cl)cc4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J11 compound treatment 0.25 0.0353 0.51 0.259 0.0499 0.84 0.9498 0.9708 1473846 ChemDiv3_015697 Cn1c(nc2ccccc12)C(O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J12 compound treatment 0.298 0.0833 1.19 0.285 0.0759 1.27 1.7438 0.9994 3125390 ChemDiv3_015698 CC(C)NC(=O)CCc1nc(no1)c2ccc(cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J13 compound treatment 0.213 -0.00166 -0.02 0.189 -0.0201 -0.34 -0.2552 -0.7549 3041491 ChemDiv3_015699 Cc1cccc(NC(=O)Cc2coc3ccc(C)cc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J14 compound treatment 0.239 0.0243 0.35 0.281 0.0719 1.21 1.0996 0.8754 3125391 ChemDiv3_015700 CC(=O)Nc1ccc2n(C)c(CN3CCCC3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J15 compound treatment 0.22 0.00534 0.08 0.226 0.0169 0.28 0.2547 0.8667 3041494 ChemDiv3_015701 COC(=O)CCc1sc(NC2CCCCC2)nc1c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J16 compound treatment 0.261 0.0463 0.66 0.29 0.0809 1.36 1.4289 0.9456 3125392 ChemDiv3_015702 Clc1ccccc1OCc2nnc(o2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J17 compound treatment 0.26 0.0453 0.65 0.246 0.0369 0.62 0.8966 0.9997 3041506 ChemDiv3_015703 CCOC(=O)c1c[nH]c2nc(NCc3ccc(Cl)cc3)nn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J18 compound treatment 0.213 -0.00166 -0.02 0.216 0.00691 0.12 0.0652 0.5512 3041508 ChemDiv3_015704 COc1ccc2n3CCN(C4CCCCC4)C5=NCCc(c53)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J19 compound treatment 0.259 0.0443 0.63 0.223 0.0139 0.23 0.6135 0.9078 3041510 ChemDiv3_015705 Cc1cccc(OCC(=O)Nc2ccc3n4CCN(Cc4nc3c2)c5ccccc5)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J20 compound treatment 0.222 0.00734 0.11 0.219 0.00991 0.17 0.1918 0.9755 1371853 ChemDiv3_015706 CN1CCN(CCOc2ccccc2OCc3cc(C)on3)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J21 compound treatment 0.264 0.0493 0.71 0.251 0.0419 0.7 0.9964 1.0 3041755 ChemDiv3_015707 Cc1ccc(NC(=O)N2CCN(CC2)c3cnccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J22 compound treatment 0.224 0.00934 0.13 0.223 0.0139 0.23 0.2595 0.965 3041758 ChemDiv3_015708 COc1ccc(CC2CC3CCN2CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J23 mock treatment 0.228 0.0133 0.19 0.251 0.0419 0.7 0.6323 0.8676 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 J24 mock treatment 0.216 0.00134 0.02 0.213 0.00391 0.07 0.06 0.8775 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K01 compound treatment 0.237 0.0223 0.32 0.197 -0.0121 -0.2 0.0825 0.2178 3125393 ChemDiv3_015709 COc1ccc(CNC(=O)c2c[nH]nc2c3ccc(OC)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K02 compound treatment 0.261 0.0463 0.66 0.261 0.0519 0.87 1.0848 0.9909 3042079 ChemDiv3_015710 Fc1ccc(NC(=O)c2cc3CSc4ccccc4-c3s2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K03 compound treatment 0.224 0.00934 0.13 0.237 0.0279 0.47 0.4257 0.874 3125394 ChemDiv3_015711 COC(=O)c1c(NC(=O)C)c2c(C)c(C)sc2n1Cc3nc(oc3C)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K04 compound treatment 0.224 0.00934 0.13 0.217 0.00791 0.13 0.1883 1.0 3042084 ChemDiv3_015712 O=C(NCc1ccccc1)C2CCN(CC2)c3nnc(s3)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K05 compound treatment 0.232 0.0173 0.25 0.241 0.0319 0.54 0.5541 0.9388 3125395 ChemDiv3_015713 CC1CCCCN1c2nnc(NC(=O)Nc3ccccc3C(F)(F)F)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K06 compound treatment 0.213 -0.00166 -0.02 0.257 0.0479 0.8 0.5518 0.686 3125396 ChemDiv3_015714 O=C(NC1CCCc2ccccc12)C3CCCN(C3)c4nnc(s4)n5cccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K07 compound treatment 0.256 0.0413 0.59 0.204 -0.00509 -0.09 0.3577 0.5987 3042095 ChemDiv3_015715 CCOC(=O)C1=C(C)NC(CS1)C(=O)NCc2cccc(OC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K08 compound treatment 0.3 0.0853 1.22 0.246 0.0369 0.62 1.3012 0.9505 3125397 ChemDiv3_015716 CC1CCN(CC1)C(=O)CN2C(=O)CSc3ncccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K09 compound treatment 0.048 -0.167 -2.38 0.06 -0.149 -2.5 -3.4551 -0.9997 3125398 ChemDiv3_015717 Cc1ccc(C)c(NCc2c[nH]nc2c3ccc(Br)cc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K10 compound treatment 0.242 0.0273 0.39 0.213 0.00391 0.07 0.3229 0.8143 3042162 ChemDiv3_015718 O=C(CCCN1C(=O)CSc2ncccc12)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K11 compound treatment 0.302 0.0873 1.25 0.231 0.0219 0.37 1.1434 0.878 3125399 ChemDiv3_015719 CC1CCN(CC1)S(=O)(=O)c2ccc3n(CC(=O)NCc4ccccc4)ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K12 compound treatment 0.219 0.00434 0.06 0.189 -0.0201 -0.34 -0.1945 -0.5673 3042169 ChemDiv3_015720 Cc1oc(nc1CSc2nc3ccncc3[nH]2)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K13 compound treatment 0.256 0.0413 0.59 0.255 0.0459 0.77 0.963 0.9915 3125400 ChemDiv3_015721 Cc1oc(nc1COc2ccccc2)c3ccc(cc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K14 compound treatment 0.218 0.00334 0.05 0.209 -9.38E-5 0.0 0.0327 0.6835 3125401 ChemDiv3_015722 CC(C)CCNC(=O)c1ccc(CSc2nc3ccncc3n2Cc4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K15 compound treatment 0.254 0.0393 0.56 0.199 -0.0101 -0.17 0.2781 0.4733 3042177 ChemDiv3_015723 Oc1ccc2nc(sc2c1)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K16 compound treatment 0.288 0.0733 1.05 0.232 0.0229 0.38 1.0137 0.9072 3125402 ChemDiv3_015724 CC(Nc1nn2c(=O)cc(C)nc2s1)C(=O)NCCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K17 compound treatment 0.228 0.0133 0.19 0.241 0.0319 0.54 0.5136 0.9035 3042182 ChemDiv3_015725 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K18 compound treatment 0.251 0.0363 0.52 0.169 -0.0401 -0.67 -0.1082 -0.1273 3125403 ChemDiv3_015726 Cc1ccc(cc1)C2C(NC(=O)c3ccccc3)C(=O)N2c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K19 compound treatment 0.243 0.0283 0.41 0.241 0.0319 0.54 0.6653 0.9906 3042246 ChemDiv3_015727 CC(C)NC(=O)CN1C(=O)c2cccnc2Oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K20 compound treatment 0.246 0.0313 0.45 0.202 -0.00709 -0.12 0.2328 0.5019 3125404 ChemDiv3_015728 O=C(NCC1(CCCC1)c2ccccc2)c3cc4CS(=O)(=O)c5ccccc5-c4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K21 compound treatment 0.233 0.0183 0.26 0.192 -0.0171 -0.29 -0.0173 -0.0446 3042251 ChemDiv3_015729 CCOc1ccccc1CNC(=O)Cn2c(C)c3cnn(c4ccccc4)c(=O)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K22 compound treatment 0.237 0.0223 0.32 0.241 0.0319 0.54 0.6047 0.9696 3125405 ChemDiv3_015730 CC1CCCCN1C(=O)CCS(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K23 mock treatment 0.232 0.0173 0.25 0.19 -0.0191 -0.32 -0.0512 -0.1263 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 K24 mock treatment 0.194 -0.0207 -0.3 0.208 -0.00109 -0.02 -0.2219 -0.7496 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L01 compound treatment 0.199 -0.0157 -0.22 0.198 -0.0111 -0.19 -0.29 -0.9958 3042257 ChemDiv3_015731 CCc1ccc(NC(=O)CN(C2=NC3CS(=O)(=O)CC3S2)c4ccc(CC)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L02 compound treatment 0.242 0.0273 0.39 0.223 0.0139 0.23 0.4416 0.9696 1915809 ChemDiv3_015732 CC(=O)NCCSc1nnnn1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L03 compound treatment 0.209 -0.00566 -0.08 0.239 0.0299 0.5 0.2977 0.5856 3125406 ChemDiv3_015733 Cc1nn(C)c2nc(C)c(CCC(=O)NCCCc3ccccc3)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L04 compound treatment 0.25 0.0353 0.51 0.22 0.0109 0.18 0.4869 0.9056 3042262 ChemDiv3_015734 CCCCC(=O)Nc1noc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L05 compound treatment 0.25 0.0353 0.51 0.254 0.0449 0.75 0.8904 0.9811 3125407 ChemDiv3_015735 Cn1c(CCCNC(=O)C2CCCCC2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L06 compound treatment 0.228 0.0133 0.19 0.226 0.0169 0.28 0.3356 0.9814 3125408 ChemDiv3_015736 CSc1ncc(Cl)c(n1)C(=O)N2CCN(CC2)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L07 compound treatment 0.24 0.0253 0.36 0.244 0.0349 0.59 0.6706 0.9734 1604251 ChemDiv3_015737 CC(C)Cc1nc2ccccc2n1CC(=O)N(C(C)C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L08 compound treatment 0.237 0.0223 0.32 0.199 -0.0101 -0.17 0.1062 0.2936 3125409 ChemDiv3_015738 C1Oc2ccccc2OC1c3nnc4sc(nn34)c5ccccn5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L09 compound treatment 0.169 -0.0457 -0.65 0.174 -0.0351 -0.59 -0.8783 -0.9987 3042330 ChemDiv3_015739 CCC(C)Cn1c(CC(C)(C)C)nc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L10 compound treatment 0.254 0.0393 0.56 0.267 0.0579 0.97 1.0852 0.9663 3125410 ChemDiv3_015740 COc1ccc(cc1OC)c2noc(CSc3nnc(CCc4ccccc4)n3C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L11 compound treatment 0.246 0.0313 0.45 0.26 0.0509 0.85 0.9212 0.9547 3042336 ChemDiv3_015741 O=C(Nc1ccccc1)N2CCC(CC2)n3c(=O)[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L12 compound treatment 0.261 0.0463 0.66 0.274 0.0649 1.09 1.239 0.9716 3125411 ChemDiv3_015742 O=C(CCc1nc(no1)c2ccccc2)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L13 compound treatment 0.279 0.0643 0.92 0.268 0.0589 0.99 1.3499 0.9994 3042339 ChemDiv3_015743 Cc1ccc2occ(CC(=O)Nc3ccc(F)cc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L14 compound treatment 0.263 0.0483 0.69 0.252 0.0429 0.72 0.9982 0.9998 3125412 ChemDiv3_015744 Oc1ccccc1c2n[nH]c3C(=O)N(CCc4ccccc4)C(c23)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L15 compound treatment 0.215 3.44E-4 0.0 0.269 0.0599 1.01 0.7144 0.7106 3042343 ChemDiv3_015745 COc1cccc(c1)c2noc(n2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L16 compound treatment 0.282 0.0673 0.96 0.259 0.0499 0.84 1.2734 0.9976 3125413 ChemDiv3_015746 Cc1ccccc1OCc2nnc(o2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L17 compound treatment 0.215 3.44E-4 0.0 0.284 0.0749 1.26 0.8925 0.7099 3041220 ChemDiv3_015747 Cc1[nH]c2nc(NCc3c(F)cccc3Cl)nn2c(=O)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L18 compound treatment 0.219 0.00434 0.06 0.045 -0.164 -2.75 -1.9035 -0.691 1356992 ChemDiv3_015748 C1CCC(CC1)c2ccc3n4CCCNC5CCCc(c54)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L19 compound treatment 0.275 0.0603 0.86 0.263 0.0539 0.9 1.2501 0.9997 3125414 ChemDiv3_015749 COCCN1CCn2c(C1)nc3cc(NC(=O)C)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L20 compound treatment 0.228 0.0133 0.19 0.262 0.0529 0.89 0.7629 0.8399 1724187 ChemDiv3_015750 OC(Cc1ccccc1)(C2CN3CCC2CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L21 compound treatment 0.275 0.0603 0.86 0.314 0.105 1.76 1.8554 0.9462 1522123 ChemDiv3_015751 Fc1ccc(cc1)C(N2CCN(CC2)C(=O)NCc3ccccc3)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L22 compound treatment 0.263 0.0483 0.69 0.277 0.0679 1.14 1.2949 0.9713 3041230 ChemDiv3_015752 Oc1ccc(CC2CC3CCN2CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L23 mock treatment 0.215 3.44E-4 0.0 0.255 0.0459 0.77 0.5483 0.7116 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 L24 mock treatment 0.221 0.00634 0.09 0.253 0.0439 0.74 0.5852 0.7882 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M01 compound treatment 0.25 0.0353 0.51 0.238 0.0289 0.49 0.7005 0.9998 3125517 ChemDiv3_015753 COc1ccc(cc1)c2n[nH]cc2C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M02 compound treatment 0.268 0.0533 0.76 0.233 0.0239 0.4 0.8233 0.955 3125518 ChemDiv3_015754 CCN1CCCC1CNC(=O)c2cc3CSc4ccccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M03 compound treatment 0.276 0.0613 0.88 0.277 0.0679 1.14 1.4264 0.9917 3125519 ChemDiv3_015755 CC1(Cc2ccccc2C(=O)N1Cc3ccco3)C(=O)NC4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M04 compound treatment 0.27 0.0553 0.79 0.227 0.0179 0.3 0.7723 0.912 3041308 ChemDiv3_015756 CCc1ccc(NC(=O)C2CCN(CC2)c3nnc(s3)n4cccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M05 compound treatment 0.255 0.0403 0.58 0.248 0.0389 0.65 0.8698 0.9981 3125520 ChemDiv3_015757 COc1ccc(CNC(=O)c2ccc3nc(sc3c2)N4CCOCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M06 compound treatment 0.268 0.0533 0.76 0.283 0.0739 1.24 1.4167 0.9728 3125521 ChemDiv3_015758 CC(NC(=O)C1CCCN(C1)c2nnc(s2)n3cccc3)c4ccc5OCCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M07 compound treatment 0.27 0.0553 0.79 0.267 0.0579 0.97 1.247 0.9948 3041314 ChemDiv3_015759 CN(CC(=O)N1CCCC1)c2nnc(s2)N3CCCC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M08 compound treatment 0.249 0.0343 0.49 0.273 0.0639 1.07 1.1058 0.9373 3041316 ChemDiv3_015760 O=C(CN1C(=O)CSc2ncccc12)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M09 compound treatment 0.271 0.0563 0.81 0.301 0.0919 1.54 1.6606 0.9542 3125522 ChemDiv3_015761 CC1Cn2c(cc3c(Cl)ccc(O1)c23)C(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M10 compound treatment 0.267 0.0523 0.75 0.276 0.0669 1.12 1.3235 0.9806 3125523 ChemDiv3_015762 CC(C)NC(=O)CCCN1C(=O)CSc2ncccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M11 compound treatment 0.239 0.0243 0.35 0.234 0.0249 0.42 0.5418 0.9959 3041393 ChemDiv3_015763 Cc1oc(nc1CN2N=C(CCC2=O)N3CCOc4ccc(Cl)cc34)c5cccc(C)c5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M12 compound treatment 0.281 0.0663 0.95 0.264 0.0549 0.92 1.3226 0.9999 3125524 ChemDiv3_015764 CCC(Sc1nc2ccncc2[nH]1)C(=O)Nc3ccccc3CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M13 compound treatment 0.307 0.0923 1.32 0.216 0.00691 0.12 1.0159 0.7662 3125525 ChemDiv3_015765 Cc1oc(nc1CSc2ccc(Cl)cc2)c3ccc(cc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M14 compound treatment 0.221 0.00634 0.09 0.235 0.0259 0.43 0.3716 0.8366 3041402 ChemDiv3_015766 CNC(=O)c1ccc(Cn2c(SCc3ccc(C)cc3)nc4ccncc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M15 compound treatment 0.26 0.0453 0.65 0.215 0.00591 0.1 0.5287 0.8058 3125526 ChemDiv3_015767 COc1ccc(cc1)C(=O)Cn2ccnc2C(=O)N3CCN(CC3)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M16 compound treatment 0.263 0.0483 0.69 0.264 0.0549 0.92 1.1406 0.99 3041405 ChemDiv3_015768 CN(CC(=O)NCc1ccccc1)c2nn3c(=O)cc(C)nc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M17 compound treatment 0.22 0.00534 0.08 0.277 0.0679 1.14 0.86 0.7528 3041454 ChemDiv3_015769 COC(=O)Cn1cc2CCc3oc(C(=O)N4CCCC4)c(C)c3-c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M18 compound treatment 0.245 0.0303 0.43 0.258 0.0489 0.82 0.8873 0.9556 3125527 ChemDiv3_015770 O=c1[nH]nc(NCc2nc3cccnc3[nH]2)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M19 compound treatment 0.257 0.0423 0.61 0.261 0.0519 0.87 1.0443 0.9842 3041457 ChemDiv3_015771 O=C(CN1C(=O)c2cccnc2Oc3ccccc13)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M20 compound treatment 0.213 -0.00166 -0.02 0.229 0.0199 0.33 0.2195 0.6553 3125528 ChemDiv3_015772 CCCN1CCN(CCCNC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M21 compound treatment 0.231 0.0163 0.23 0.242 0.0329 0.55 0.5558 0.9268 1066700 ChemDiv3_015773 CCOC(=O)c1cc2ccccc2n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M22 compound treatment 0.225 0.0103 0.15 0.196 -0.0131 -0.22 -0.0508 -0.1917 3125529 ChemDiv3_015774 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)CCC(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M23 mock treatment 0.216 0.00134 0.02 0.171 -0.0381 -0.64 -0.4385 -0.6855 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 M24 mock treatment 0.218 0.00334 0.05 0.239 0.0299 0.5 0.3887 0.771 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N01 compound treatment 0.267 0.0523 0.75 0.277 0.0679 1.14 1.3353 0.9792 3041466 ChemDiv3_015775 CCCN(CCC)C(=O)Cc1c(C)nc2c(c(C)nn2c1C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N02 compound treatment 0.219 0.00434 0.06 0.211 0.00191 0.03 0.0666 0.9524 3125530 ChemDiv3_015776 CC(C)(C)C(=O)NCCSc1nnnn1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N03 compound treatment 0.238 0.0233 0.33 0.251 0.0419 0.7 0.7335 0.942 3042709 ChemDiv3_015777 O=c1n(CCCN2CCCC2)cnc3c4ccccc4[nH]c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N04 compound treatment 0.25 0.0353 0.51 0.221 0.0119 0.2 0.4988 0.9175 3042710 ChemDiv3_015778 O=S(=O)(Cc1ccccc1)Nc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N05 compound treatment 0.29 0.0753 1.08 0.209 -9.38E-5 0.0 0.7609 0.7061 3042711 ChemDiv3_015779 Fc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N06 compound treatment 0.27 0.0553 0.79 0.221 0.0119 0.2 0.7011 0.8587 3042712 ChemDiv3_015780 CCSc1ncc(Cl)c(n1)C(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N07 compound treatment 0.261 0.0463 0.66 0.147 -0.0621 -1.04 -0.2682 -0.2171 3042713 ChemDiv3_015781 CCc1nc2ccccc2n1CCCOc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N08 compound treatment 0.221 0.00634 0.09 0.211 0.00191 0.03 0.0868 0.902 3042714 ChemDiv3_015782 C(c1nn2c(Cn3cnc4ccccc34)nnc2s1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N09 compound treatment 0.106 -0.109 -1.55 0.13 -0.0791 -1.33 -2.0377 -0.9969 3042715 ChemDiv3_015783 CC(C)CCn1c(CC(C)(C)C)nc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N10 compound treatment 0.291 0.0763 1.09 0.331 0.122 2.05 2.219 0.9568 3125531 ChemDiv3_015784 CCOc1ccc(cc1)C2SCC(=O)Nc3c2c(O)nn3C4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N11 compound treatment 0.057 -0.158 -2.26 0.063 -0.146 -2.45 -3.3284 -0.9991 1065280 ChemDiv3_015785 Oc1ccc(CN2CCCCC2)c3cccnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N12 compound treatment 0.291 0.0763 1.09 0.267 0.0579 0.97 1.4594 0.9983 3042716 ChemDiv3_015786 CC(C)NC(=O)CCc1nc(no1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N13 compound treatment 0.26 0.0453 0.65 0.319 0.11 1.84 1.763 0.9016 3125532 ChemDiv3_015787 CCc1ccc2occ(CC(=O)Nc3ccc(Cl)cc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N14 compound treatment 0.268 0.0533 0.76 0.288 0.0789 1.32 1.476 0.9657 3125533 ChemDiv3_015788 CSc1ncc(Cl)c(n1)C(=O)N(Cc2ccccc2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N15 compound treatment 0.288 0.0733 1.05 0.241 0.0319 0.54 1.1205 0.9513 3042717 ChemDiv3_015789 COc1nc2c(C)cccc2cc1c3noc(n3)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N16 compound treatment 0.261 0.0463 0.66 0.226 0.0169 0.28 0.6694 0.9283 3125534 ChemDiv3_015790 C(Oc1ccc2ccccc2c1)c3nnc(o3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N17 compound treatment 0.282 0.0673 0.96 0.252 0.0429 0.72 1.1903 0.9897 3042718 ChemDiv3_015791 Cc1[nH]c2nc(COc3ccccc3)nn2c(=O)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N18 compound treatment 0.262 0.0473 0.68 0.204 -0.00509 -0.09 0.4184 0.613 3125535 ChemDiv3_015792 C1Cc2c([nH]c3ccccc23)C4N(NC=C14)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N19 compound treatment 0.271 0.0563 0.81 0.282 0.0729 1.22 1.4351 0.9795 3042719 ChemDiv3_015793 CN(Cc1nc2ccccc2n1C)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N20 compound treatment 0.263 0.0483 0.69 0.231 0.0219 0.37 0.7489 0.9563 1201745 ChemDiv3_015794 OC(Cc1ccccc1)(Cc2ccccc2)C3CN4CCC3CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N21 compound treatment 0.249 0.0343 0.49 0.206 -0.00309 -0.05 0.3106 0.6289 3125536 ChemDiv3_015795 O=C(NCCSc1nnnn1c2ccccc2)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N22 compound treatment 0.251 0.0363 0.52 0.209 -9.38E-5 0.0 0.3665 0.705 1526524 ChemDiv3_015796 Clc1ccc(OCC(=O)NC2CN3CCC2CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N23 mock treatment 0.244 0.0293 0.42 0.256 0.0469 0.79 0.8535 0.9566 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 N24 mock treatment 0.235 0.0203 0.29 0.24 0.0309 0.52 0.5726 0.9626 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O01 compound treatment 0.261 0.0463 0.66 0.252 0.0429 0.72 0.9779 0.9991 3125537 ChemDiv3_015797 COc1ccc(cc1)c2n[nH]cc2C(=O)NCCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O02 compound treatment 0.228 0.0133 0.19 0.252 0.0429 0.72 0.6442 0.8647 3042720 ChemDiv3_015798 C(CNc1nc2ccccc2n3nnnc13)CN4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O03 compound treatment 0.257 0.0423 0.61 0.224 0.0149 0.25 0.6052 0.9235 3125538 ChemDiv3_015799 CCCN1C(=O)c2ccccc2CC1(C)C(=O)NC3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O04 compound treatment 0.272 0.0573 0.82 0.254 0.0449 0.75 1.1129 0.9991 3125539 ChemDiv3_015800 CC(C)CCNC(=O)C1CCN(CC1)c2nnc(s2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O05 compound treatment 0.244 0.0293 0.42 0.227 0.0179 0.3 0.5093 0.9866 3042721 ChemDiv3_015801 COC(=O)c1ccc2SCC(=O)N(CC(=O)N3CCOc4ccc(C)cc34)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O06 compound treatment 0.281 0.0663 0.95 0.226 0.0169 0.28 0.8717 0.88 3125540 ChemDiv3_015802 CNC(=O)C1CCN(CC1)c2nnc(s2)n3c(C)ccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O07 compound treatment 0.27 0.0553 0.79 0.259 0.0499 0.84 1.1521 0.9996 3125541 ChemDiv3_015803 COc1cccc(CNC(=O)c2cnn3c4CCCCCc4cnc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O08 compound treatment 0.24 0.0253 0.36 0.273 0.0639 1.07 1.0148 0.8963 3042722 ChemDiv3_015804 CC1CCC(CC1)NC(=O)CN2C(=O)CSc3ncccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O09 compound treatment 0.222 0.00734 0.11 0.255 0.0459 0.77 0.6191 0.7961 3123629 ChemDiv3_015805 CC1Cn2c(cc3c(Cl)ccc(O1)c23)C(=O)N4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O10 compound treatment 0.214 -6.56E-4 -0.01 0.225 0.0159 0.27 0.1821 0.6818 3042723 ChemDiv3_015806 CCNC(=O)CN1C(=O)CSc2nc(C)cc(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O11 compound treatment 0.251 0.0363 0.52 0.227 0.0179 0.3 0.5801 0.9661 3123503 ChemDiv3_015807 O=C(NCCCN1CCOCC1)c2ccc(CN3C(=O)CCn4nccc34)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O12 compound treatment 0.235 0.0203 0.29 0.234 0.0249 0.42 0.5014 0.9843 3042724 ChemDiv3_015808 CCC(Sc1nc2ccncc2[nH]1)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O13 compound treatment 0.235 0.0203 0.29 0.24 0.0309 0.52 0.5726 0.9626 3123504 ChemDiv3_015809 Cc1oc(nc1CN2CCCCC2)c3ccc(cc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O14 compound treatment 0.246 0.0313 0.45 0.213 0.00391 0.07 0.3634 0.802 3123505 ChemDiv3_015810 CNC(=O)c1ccc(Cn2c(SCc3ccc(F)cc3)nc4ccncc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O15 compound treatment 0.228 0.0133 0.19 0.225 0.0159 0.27 0.3237 0.9865 3042725 ChemDiv3_015811 Cc1ccc(CSc2nc3ccncc3n2Cc4ccc(cc4)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O16 compound treatment 0.213 -0.00166 -0.02 0.237 0.0279 0.47 0.3144 0.6705 3123506 ChemDiv3_015812 CCN1CCN(CC1)C(=O)C(C)n2c(C)c3cnn(c4ccccc4)c(=O)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O17 compound treatment 0.221 0.00634 0.09 0.229 0.0199 0.33 0.3004 0.8677 3042726 ChemDiv3_015813 Cc1ccccc1Cn2cc(CCCC(=O)O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O18 compound treatment 0.248 0.0333 0.48 0.23 0.0209 0.35 0.5854 0.9886 3123507 ChemDiv3_015814 Cc1cc(C)n2nc(CNC(=O)Nc3ccccc3Cl)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O19 compound treatment 0.23 0.0153 0.22 0.228 0.0189 0.32 0.3796 0.9838 3042727 ChemDiv3_015815 Cc1nn(CC(=O)O)c(=O)c2cccn12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O20 compound treatment 0.23 0.0153 0.22 0.234 0.0249 0.42 0.4508 0.9548 3123508 ChemDiv3_015816 Cc1ccccc1NC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O21 compound treatment 0.212 -0.00266 -0.04 0.209 -9.38E-5 0.0 -0.028 -0.7358 3123509 ChemDiv3_015817 CC1CN(C(=O)N2CCC(CC2)C(=O)O)c3cc(C)ccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O22 compound treatment 0.206 -0.00866 -0.12 0.216 0.00691 0.12 -0.0056 -0.0329 3042728 ChemDiv3_015818 CN(C(=O)CCS(=O)(=O)c1ccc2n(C)c(=O)c(=O)n(C)c2c1)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O23 mock treatment 0.218 0.00334 0.05 0.224 0.0149 0.25 0.2107 0.8273 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 O24 mock treatment 0.22 0.00534 0.08 0.203 -0.00609 -0.1 -0.0183 -0.1431 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P01 compound treatment 0.248 0.0333 0.48 0.274 0.0649 1.09 1.1076 0.9313 3123510 ChemDiv3_015819 Cc1nc2cc(nn2c(C)c1CC(=O)N3CCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P02 compound treatment 0.26 0.0453 0.65 0.224 0.0149 0.25 0.6355 0.9142 3123511 ChemDiv3_015820 COc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)N3CCc4cc(OC)c(OC)cc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P03 compound treatment 0.251 0.0363 0.52 0.249 0.0399 0.67 0.8412 0.9922 3042729 ChemDiv3_015821 CCCN(CCC)CCn1cnc2c3ccccc3[nH]c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P04 compound treatment 0.259 0.0443 0.63 0.243 0.0339 0.57 0.8509 0.9985 3123512 ChemDiv3_015822 O=C1CCCN1c2ccc(cc2)S(=O)(=O)Nc3noc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P05 compound treatment 0.274 0.0593 0.85 0.268 0.0589 0.99 1.2993 0.9971 3042730 ChemDiv3_015823 CCCCn1c(nc2ccccc12)C3CN(C(=O)C3)c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P06 compound treatment 0.271 0.0563 0.81 0.27 0.0609 1.02 1.2927 0.9931 3123513 ChemDiv3_015824 CCSc1ncc(Cl)c(n1)C(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P07 compound treatment 0.261 0.0463 0.66 0.252 0.0429 0.72 0.9779 0.9991 3042731 ChemDiv3_015825 CC(C)c1nc2ccccc2n1CCCOc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P08 compound treatment 0.268 0.0533 0.76 0.215 0.00591 0.1 0.6096 0.7923 3123514 ChemDiv3_015826 COc1ccc(Cc2nn3c(nnc3s2)c4ccccc4Br)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P09 compound treatment 0.277 0.0623 0.89 0.187 -0.0221 -0.37 0.3683 0.3814 3042732 ChemDiv3_015827 CCCn1c(nc2ccccc12)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P10 compound treatment 0.245 0.0303 0.43 0.267 0.0579 0.97 0.9941 0.934 3123515 ChemDiv3_015828 Cc1cccc(c1)c2noc(CCC(=O)NC(C)(C)C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P11 compound treatment 0.334 0.119 1.71 0.306 0.0969 1.63 2.3572 0.9997 3123516 ChemDiv3_015829 Oc1ccc(CN2CCN(CC2)c3ccccc3)c4cccnc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P12 compound treatment 0.201 -0.0137 -0.2 0.312 0.103 1.73 1.0832 0.6232 3042733 ChemDiv3_015830 Cc1cc(C)c2c(O)nc(SCc3ccccc3C)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P13 compound treatment 0.267 0.0523 0.75 0.261 0.0519 0.87 1.1454 0.9972 1868220 ChemDiv3_015831 COc1ccc(CNC(=O)Cc2coc3cc(C)cc(C)c23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P14 compound treatment 0.26 0.0453 0.65 0.229 0.0199 0.33 0.6949 0.9524 3042734 ChemDiv3_015832 O=C(Cc1ccccc1)n2cnc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P15 compound treatment 0.251 0.0363 0.52 0.191 -0.0181 -0.3 0.1529 0.2539 3123517 ChemDiv3_015833 CN(Cc1cc2cc(C)ccc2nc1O)C(=O)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P16 compound treatment 0.262 0.0473 0.68 0.242 0.0329 0.55 0.8694 0.9949 1151784 ChemDiv3_015834 CCOc1ccc(cc1)C2N(C(=O)Cc3cc(OC)c(OC)cc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P17 compound treatment 0.287 0.0723 1.03 0.272 0.0629 1.06 1.4783 0.9999 3123518 ChemDiv3_015835 Fc1cccc(Cl)c1CNc2nc3[nH]c4CCCc4c(=O)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P18 compound treatment 0.05 -0.165 -2.36 0.042 -0.167 -2.8 -3.6485 -0.9962 1472490 ChemDiv3_015836 COc1ccc2n3CCN(C)c4nc(nc(c2c1)c43)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P19 compound treatment 0.269 0.0543 0.78 0.256 0.0469 0.79 1.1063 1.0 3042735 ChemDiv3_015837 CN(Cc1nc2ccccc2n1C)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P20 compound treatment 0.272 0.0573 0.82 0.246 0.0369 0.62 1.018 0.9904 1490763 ChemDiv3_015838 CC(=O)OC1(Cc2ccccc2)CN3CCC1c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P21 compound treatment 0.275 0.0603 0.86 0.273 0.0639 1.07 1.3688 0.9942 3123519 ChemDiv3_015839 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)Nc3ccc(C)cc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P22 compound treatment 0.299 0.0843 1.21 0.245 0.0359 0.6 1.2792 0.9486 3042736 ChemDiv3_015840 CCCCn1c2nc(cn2c3ccccc13)c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P23 mock treatment 0.255 0.0403 0.58 0.232 0.0229 0.38 0.6799 0.9805 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2045 P24 mock treatment 0.222 0.00734 0.11 0.22 0.0109 0.18 0.2037 0.9652 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A01 compound treatment 0.205 -0.0235 -0.34 0.217 -0.019 -0.32 -0.4629 -0.9997 3123520 ChemDiv3_015841 Cc1ccc(cc1)c2noc(CN(C3CCCCC3)S(=O)(=O)c4ccccc4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A02 compound treatment 0.232 0.00353 0.05 0.211 -0.025 -0.42 -0.261 -0.6175 3042737 ChemDiv3_015842 COc1ccc(cc1OC)c2noc(CN(C3CCCCC3)C(=O)Nc4cccc(Cl)c4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A03 compound treatment 0.222 -0.00647 -0.09 0.189 -0.047 -0.79 -0.6232 -0.7847 3123521 ChemDiv3_015843 Cc1ccc(cc1)c2noc(CNC(=O)C(c3ccccc3)c4ccccc4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A04 compound treatment 0.218 -0.0105 -0.15 0.192 -0.044 -0.74 -0.6281 -0.8335 3042738 ChemDiv3_015844 Cc1ccc2cnn(CC(=O)NC3CCCCC3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A05 compound treatment 0.202 -0.0265 -0.38 0.196 -0.04 -0.67 -0.7424 -0.9633 3123522 ChemDiv3_015845 CN(CC(=O)NCc1nc(no1)c2cccc(C)c2)S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A06 compound treatment 0.207 -0.0215 -0.31 0.218 -0.018 -0.3 -0.4308 -1.0 3042739 ChemDiv3_015846 CN(C)CCNC(=O)Cn1ncc2c(Cl)cccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A07 compound treatment 0.207 -0.0215 -0.31 0.205 -0.031 -0.52 -0.5851 -0.9684 3123523 ChemDiv3_015847 CC(=O)N1CCN(CC1)c2ncnc3[nH]cnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A08 compound treatment 0.2 -0.0285 -0.41 0.215 -0.021 -0.35 -0.5372 -0.9974 3123524 ChemDiv3_015848 Cc1ccc2n(ncc2c1)C(=O)CCCC(=O)N3CCN(CC3)c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A09 compound treatment 0.198 -0.0305 -0.44 0.268 0.032 0.54 0.0716 0.1035 3042740 ChemDiv3_015849 Cc1cccc(OCCn2c(CNC(=O)c3ccccc3)nc4ccccc24)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A10 compound treatment 0.228 -4.69E-4 -0.01 0.215 -0.021 -0.35 -0.254 -0.7204 3123525 ChemDiv3_015850 Clc1cccc(NC(=O)n2ncc3cc(Cl)ccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A11 compound treatment 0.221 -0.00747 -0.11 0.264 0.028 0.47 0.2568 0.5328 3123526 ChemDiv3_015851 CCOc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A12 compound treatment 0.243 0.0145 0.21 0.239 0.003 0.05 0.1826 0.8537 3042741 ChemDiv3_015852 CN1C(=O)c2ccccc2Sc3ccc(NC(=O)N4CCCC4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A13 compound treatment 0.211 -0.0175 -0.25 0.226 -0.01 -0.17 -0.2954 -0.9813 3123527 ChemDiv3_015853 O=C(CCCc1nc(no1)c2ccccc2)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A14 compound treatment 0.221 -0.00747 -0.11 0.218 -0.018 -0.3 -0.2892 -0.9024 3123528 ChemDiv3_015854 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)NC4CCCC4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A15 compound treatment 0.213 -0.0155 -0.22 0.232 -0.004 -0.07 -0.2039 -0.882 3042742 ChemDiv3_015855 Cc1cc(Nc2ccccc2)n3cnnc3n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A16 compound treatment 0.23 0.00153 0.02 0.222 -0.014 -0.23 -0.1507 -0.6384 3123630 ChemDiv3_015856 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A17 compound treatment 0.192 -0.0365 -0.52 0.211 -0.025 -0.42 -0.6656 -0.9942 3042900 ChemDiv3_015857 C(Nc1cc(nc2nncn12)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A18 compound treatment 0.217 -0.0115 -0.16 0.253 0.017 0.29 0.0858 0.2606 3042957 ChemDiv3_015858 CC1CN(C(=O)CCC(=O)NC2CCCC(C)C2C)c3cc(Cl)ccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A19 compound treatment 0.202 -0.0265 -0.38 0.223 -0.013 -0.22 -0.422 -0.9657 3042958 ChemDiv3_015859 Cn1c(nc2ccccc12)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A20 compound treatment 0.215 -0.0135 -0.19 0.195 -0.041 -0.69 -0.6228 -0.8716 3042959 ChemDiv3_015860 O=C(CCC(=O)N1CCOc2ccccc12)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A21 compound treatment 0.249 0.0205 0.29 0.249 0.013 0.22 0.3619 0.9893 3042961 ChemDiv3_015861 Cc1cccc(NC(=O)NCc2nc(no2)c3cccc(C)c3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A22 compound treatment 0.206 -0.0225 -0.32 0.235 -0.001 -0.02 -0.2391 -0.743 3042963 ChemDiv3_015862 CN(CC(=O)NCc1ccccc1)c2nnc(s2)N3CCCC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A23 mock treatment 0.217 -0.0115 -0.16 0.229 -0.007 -0.12 -0.1991 -0.9866 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 A24 mock treatment 0.189 -0.0395 -0.56 0.252 0.016 0.27 -0.2093 -0.3348 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B01 compound treatment 0.211 -0.0175 -0.25 0.231 -0.005 -0.08 -0.236 -0.8954 3042964 ChemDiv3_015863 CN(C(=O)C1=CC(=NS(=O)(=O)N1C)c2ccc(C)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B02 compound treatment 0.226 -0.00247 -0.04 0.256 0.02 0.34 0.2124 0.6292 3042965 ChemDiv3_015864 CC(CCc1ccccc1)NC(=O)Cc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B03 compound treatment 0.224 -0.00447 -0.06 0.244 0.008 0.13 0.0497 0.3345 3123631 ChemDiv3_015865 CCc1ccccc1NC(=O)C2=CC(=NS(=O)(=O)N2C)c3cccc(OC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B04 compound treatment 0.238 0.00953 0.14 0.241 0.005 0.08 0.1557 0.9728 3042967 ChemDiv3_015866 Cc1ccc2onc(CC(=O)NC3CCCCC3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B05 compound treatment 0.259 0.0305 0.44 0.256 0.02 0.34 0.5462 0.9916 3123632 ChemDiv3_015867 CN1C(=CC(=NS1(=O)=O)c2ccco2)C(=O)NCC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B06 compound treatment 0.219 -0.00947 -0.14 0.221 -0.015 -0.25 -0.2738 -0.9577 3042969 ChemDiv3_015868 CCCNC(=O)c1nnc(Cc2ccc3OCOc3c2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B07 compound treatment 0.236 0.00753 0.11 0.239 0.003 0.05 0.1118 0.94 3123633 ChemDiv3_015869 COC(=O)c1cc(cn1C)S(=O)(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B08 compound treatment 0.215 -0.0135 -0.19 0.275 0.039 0.65 0.3266 0.4787 3123634 ChemDiv3_015870 COc1ccccc1Cn2ccn(CC(=O)NCCc3ccccc3)c(=O)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B09 compound treatment 0.23 0.00153 0.02 0.238 0.002 0.03 0.0392 0.9786 3042972 ChemDiv3_015871 Cn1nc(C(=O)NCCCN2CCN(CC2)c3ccccc3)c4COc5ccccc5-c41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B10 compound treatment 0.197 -0.0315 -0.45 0.271 0.035 0.59 0.0971 0.1312 3123635 ChemDiv3_015872 CCCN1CCN(CC1)C(=O)c2sc3nc4CCCCn4c(=O)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B11 compound treatment 0.222 -0.00647 -0.09 0.266 0.03 0.5 0.2906 0.5677 3123636 ChemDiv3_015873 COC(=O)NCC(N1CCOCC1)c2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B12 compound treatment 0.225 -0.00347 -0.05 0.228 -0.008 -0.13 -0.13 -0.9084 3042974 ChemDiv3_015874 CC1CC(C)CN(CCCNC(=O)c2cccc3C(=O)CCSc23)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B13 compound treatment 0.229 5.31E-4 0.01 0.207 -0.029 -0.49 -0.3388 -0.696 3123637 ChemDiv3_015875 CCC(=O)Nc1nn2c(C)nnc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B14 compound treatment 0.232 0.00353 0.05 0.222 -0.014 -0.23 -0.1304 -0.5427 3123638 ChemDiv3_015876 Cc1ccc(N2CCN(CC2)C(=O)c3nc(no3)c4ccncc4)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B15 compound treatment 0.22 -0.00847 -0.12 0.229 -0.007 -0.12 -0.1687 -0.9999 3042976 ChemDiv3_015877 CCOC(=O)CSc1nc2nccnc2c(=O)n1CCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B16 compound treatment 0.243 0.0145 0.21 0.267 0.031 0.52 0.5149 0.919 3123639 ChemDiv3_015878 CC1CN(C(=O)N2CCCC(C2)C(=O)NCCCc3ccccc3)c4cc(C)ccc4O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B17 compound treatment 0.235 0.00653 0.09 0.248 0.012 0.2 0.2085 0.939 3042978 ChemDiv3_015879 CCc1ccc(NS(=O)(=O)c2ccc3N(C)CCOc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B18 compound treatment 0.237 0.00853 0.12 0.264 0.028 0.47 0.4186 0.8621 3123640 ChemDiv3_015880 Cn1cc(CCCC(=O)N2CCCC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B19 compound treatment 0.238 0.00953 0.14 0.251 0.015 0.25 0.2744 0.9585 3042980 ChemDiv3_015881 CCN(c1ccccc1)S(=O)(=O)c2ccc3N(CCOc3c2)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B20 compound treatment 0.216 -0.0125 -0.18 0.285 0.049 0.82 0.4554 0.5412 3123641 ChemDiv3_015882 Oc1ccccc1c2cc(on2)C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B21 compound treatment 0.243 0.0145 0.21 0.234 -0.002 -0.03 0.1232 0.5853 3123642 ChemDiv3_015883 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)NC(C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B22 compound treatment 0.221 -0.00747 -0.11 0.268 0.032 0.54 0.3042 0.5556 3042982 ChemDiv3_015884 Cc1cc2NC(=O)COc2cc1S(=O)(=O)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B23 mock treatment 0.234 0.00553 0.08 0.259 0.023 0.39 0.3289 0.8347 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 B24 mock treatment 0.245 0.0165 0.24 0.229 -0.007 -0.12 0.0841 0.3186 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C01 compound treatment 0.205 -0.0235 -0.34 0.207 -0.029 -0.49 -0.5815 -0.9835 3043012 ChemDiv3_015885 O=C(CCCN1C(=O)c2ccccc2C1=O)N(Cc3nc(no3)c4ccccc4)C5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C02 compound treatment 0.057 -0.171 -2.45 0.23 -0.006 -0.1 -1.8055 -0.7355 3043014 ChemDiv3_015886 Oc1ccc(cc1)c2nc(c([nH]2)c3ccc(O)cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C03 compound treatment 0.297 0.0685 0.98 0.307 0.071 1.19 1.5358 0.9953 3043015 ChemDiv3_015887 Cc1cccc(c1)c2noc(CNC(=O)C(C)(C)Oc3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C04 compound treatment 0.201 -0.0275 -0.39 0.269 0.033 0.55 0.1138 0.1676 3043017 ChemDiv3_015888 CC1CC(C)CN(C1)C(=O)Cn2ncc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C05 compound treatment 0.082 -0.146 -2.1 0.232 -0.004 -0.07 -1.5289 -0.7294 3043018 ChemDiv3_015889 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)NCc3nc(no3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C06 compound treatment 0.246 0.0175 0.25 0.247 0.011 0.18 0.3079 0.9887 3043019 ChemDiv3_015890 Cc1ccc2n(ncc2c1)C(=O)CCCC(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C07 compound treatment 0.089 -0.139 -1.99 0.264 0.028 0.47 -1.0783 -0.5261 3123643 ChemDiv3_015891 CC(C)C(=O)n1nc(nc1NCc2cccs2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C08 compound treatment 0.058 -0.17 -2.44 0.041 -0.195 -3.27 -4.0384 -0.9895 3043021 ChemDiv3_015892 O=C(CCC(=O)n1ncc2ccccc12)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C09 compound treatment 0.217 -0.0115 -0.16 0.249 0.013 0.22 0.0383 0.1403 3123644 ChemDiv3_015893 CC(C)CCn1c(CNC(=O)c2ccccc2)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C10 compound treatment 0.225 -0.00347 -0.05 0.239 0.003 0.05 5.0E-4 0.0074 3123645 ChemDiv3_015894 O=C(NCc1c(sc2CCCCc12)n3cccc3)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C11 compound treatment 0.229 5.31E-4 0.01 0.252 0.016 0.27 0.1953 0.7268 3043024 ChemDiv3_015895 CCOc1ccc(cc1)N2CC(CC2=O)c3nc4ccccc4n3Cc5ccc(F)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C12 compound treatment 0.051 -0.177 -2.54 0.241 0.005 0.08 -1.7356 -0.6834 3123646 ChemDiv3_015896 CCc1ccc(NC(=O)Nc2ccc3Sc4ccccc4C(=O)N(C)c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C13 compound treatment 0.039 -0.189 -2.71 0.256 0.02 0.34 -1.679 -0.6148 3043026 ChemDiv3_015897 CNC(=O)CCCc1nc(no1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C14 compound treatment 0.209 -0.0195 -0.28 0.241 0.005 0.08 -0.1376 -0.473 3123647 ChemDiv3_015898 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)Nc4ccc(CC)cc4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C15 compound treatment 0.07 -0.158 -2.27 0.255 0.019 0.32 -1.3773 -0.6017 3043029 ChemDiv3_015899 C1Cc2nc3nncn3c(Nc4ccccc4)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C16 compound treatment 0.22 -0.00847 -0.12 0.212 -0.024 -0.4 -0.3705 -0.8808 3123648 ChemDiv3_015900 Fc1ccc(CNC(=O)CCSCc2cnn(c2n3cccc3)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C17 compound treatment 0.2 -0.0285 -0.41 0.233 -0.003 -0.05 -0.3235 -0.7885 3043031 ChemDiv3_015901 C1CCN(C1)c2cc(nc3nncn23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C18 compound treatment 0.217 -0.0115 -0.16 0.245 0.009 0.15 -0.0092 -0.0412 3123649 ChemDiv3_015902 CCOc1ccccc1CNC(=O)CCC(=O)N2CC(C)Oc3ccc(Cl)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C19 compound treatment 0.218 -0.0105 -0.15 0.215 -0.021 -0.35 -0.3551 -0.9273 3043033 ChemDiv3_015903 CC(C)Cn1c(nc2ccccc12)C3CN(CC=C)C(=O)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C20 compound treatment 0.214 -0.0145 -0.21 0.214 -0.022 -0.37 -0.4074 -0.9625 3123650 ChemDiv3_015904 COc1ccc(cc1)c2cc3c(=O)n(CC(=O)NC4CCC(C)CC4)ncn3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C21 compound treatment 0.237 0.00853 0.12 0.24 0.004 0.07 0.1338 0.9604 3123651 ChemDiv3_015905 CN(Cc1nc(no1)c2ccc(C)cc2)C(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C22 compound treatment 0.192 -0.0365 -0.52 0.23 -0.006 -0.1 -0.4401 -0.8283 3043036 ChemDiv3_015906 CN(CC(=O)NC1CCCCC1)c2nnc(s2)N3CCCC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C23 mock treatment 0.23 0.00153 0.02 0.23 -0.006 -0.1 -0.0557 -0.5407 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 C24 mock treatment 0.201 -0.0275 -0.39 0.211 -0.025 -0.42 -0.5745 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D01 compound treatment 0.179 -0.0495 -0.71 0.209 -0.027 -0.45 -0.8208 -0.9768 3123652 ChemDiv3_015907 CN1C(=CC(=NS1(=O)=O)c2ccc(C)cc2)C(=O)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D02 compound treatment 0.203 -0.0255 -0.36 0.218 -0.018 -0.3 -0.4712 -0.9957 3043069 ChemDiv3_015908 CCc1ccccc1NC(=O)Cc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D03 compound treatment 0.226 -0.00247 -0.04 0.202 -0.034 -0.57 -0.4285 -0.7494 3043071 ChemDiv3_015909 CN1C(=CC(=NS1(=O)=O)c2ccc(F)cc2)C(=O)Nc3ccc(F)cc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D04 compound treatment 0.221 -0.00747 -0.11 0.273 0.037 0.62 0.3636 0.577 3043072 ChemDiv3_015910 COc1cc(OC)c(NC(=O)Cc2noc3ccc(C)cc23)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D05 compound treatment 0.226 -0.00247 -0.04 0.264 0.028 0.47 0.3073 0.6521 3043074 ChemDiv3_015911 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)Nc3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D06 compound treatment 0.239 0.0105 0.15 0.239 0.003 0.05 0.1421 0.8948 3043076 ChemDiv3_015912 O=C(NCCCN1CCOCC1)c2nnc(o2)c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D07 compound treatment 0.206 -0.0225 -0.32 0.234 -0.002 -0.03 -0.251 -0.7767 3043077 ChemDiv3_015913 O=C(CSc1nc2CCN(Cc3ccccc3)Cc2c(=O)[nH]1)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D08 compound treatment 0.232 0.00353 0.05 0.245 0.009 0.15 0.1425 0.8948 3043079 ChemDiv3_015914 COc1ccc(Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D09 compound treatment 0.268 0.0395 0.57 0.28 0.044 0.74 0.922 0.9913 3123653 ChemDiv3_015915 Cn1nc(C(=O)N2CCCC2)c3CSc4ccccc4-c31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D10 compound treatment 0.239 0.0105 0.15 0.308 0.072 1.21 0.961 0.7891 3043081 ChemDiv3_015916 CN(C(=O)c1sc2nc3CCCCn3c(=O)c2c1C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D11 compound treatment 0.041 -0.187 -2.68 0.258 0.022 0.37 -1.635 -0.604 3123654 ChemDiv3_015917 COc1cccc(c1)c2nnc3sc(NC(=O)C)nn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D12 compound treatment 0.284 0.0555 0.79 0.295 0.059 0.99 1.2619 0.994 3043082 ChemDiv3_015918 CN(C(=O)c1cccc2C(=O)CCSc12)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D13 compound treatment 0.24 0.0115 0.16 0.26 0.024 0.4 0.4015 0.9223 3123655 ChemDiv3_015919 CCCCC(=O)Nc1nn2c(nnc2s1)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D14 compound treatment 0.239 0.0105 0.15 0.237 0.001 0.02 0.1184 0.7811 3123656 ChemDiv3_015920 CN(Cc1ccccc1)C(=O)c2nc(no2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D15 compound treatment 0.244 0.0155 0.22 0.218 -0.018 -0.3 -0.0565 -0.1508 3043085 ChemDiv3_015921 COc1cccc(CSc2nc3nccnc3c(=O)n2CCc4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D16 compound treatment 0.232 0.00353 0.05 0.236 0.0 0.0 0.0357 0.7071 3123657 ChemDiv3_015922 CCOC(=O)Cc1ccc(NC(=O)N2CCOc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D17 compound treatment 0.234 0.00553 0.08 0.267 0.031 0.52 0.4239 0.8054 3123762 ChemDiv3_015923 Cn1cc(cc1C(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D18 compound treatment 0.255 0.0265 0.38 0.242 0.006 0.1 0.3396 0.8648 3043087 ChemDiv3_015924 CCn1cc(CCCC(=O)NCCN2CCN(C)CC2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D19 compound treatment 0.238 0.00953 0.14 0.242 0.006 0.1 0.1676 0.9889 3123763 ChemDiv3_015925 CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D20 compound treatment 0.168 -0.0605 -0.86 0.132 -0.104 -1.75 -1.8459 -0.9475 3043089 ChemDiv3_015926 Oc1ccccc1c2cc(on2)C(=O)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D21 compound treatment 0.235 0.00653 0.09 0.252 0.016 0.27 0.2559 0.9002 3123764 ChemDiv3_015927 Fc1ccc(NC(=O)Cc2noc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D22 compound treatment 0.245 0.0165 0.24 0.212 -0.024 -0.4 -0.1176 -0.2518 3123765 ChemDiv3_015928 COc1ccc(CCNS(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D23 mock treatment 0.252 0.0235 0.34 0.22 -0.016 -0.27 0.0481 0.1117 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 D24 mock treatment 0.215 -0.0135 -0.19 0.226 -0.01 -0.17 -0.2549 -0.9976 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E01 compound treatment 0.216 -0.0125 -0.18 0.226 -0.01 -0.17 -0.2448 -0.9995 3043091 ChemDiv3_015929 CC(C)N(Cc1nc(no1)c2cccc(C)c2)C(=O)C3CCC(=O)N3S(=O)(=O)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E02 compound treatment 0.252 0.0235 0.34 0.217 -0.019 -0.32 0.0125 0.027 3123766 ChemDiv3_015930 Brc1ccc(s1)c2nc(c3cccs3)c([nH]2)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E03 compound treatment 0.22 -0.00847 -0.12 0.25 0.014 0.23 0.0805 0.3045 3043093 ChemDiv3_015931 O=S(=O)(NCc1nc(no1)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E04 compound treatment 0.206 -0.0225 -0.32 0.28 0.044 0.74 0.2949 0.3662 3043129 ChemDiv3_015932 CCc1ccc(NC(=O)Nc2nnc(s2)N(CC(C)C)CC(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E05 compound treatment 0.247 0.0185 0.27 0.255 0.019 0.32 0.4129 0.9958 3043130 ChemDiv3_015933 C(NC1CCCCC1)c2nc(no2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E06 compound treatment 0.246 0.0175 0.25 0.237 0.001 0.02 0.1892 0.7528 3043132 ChemDiv3_015934 Clc1ccc2cnn(C(=O)CCC(=O)NC3CCCc4ccccc34)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E07 compound treatment 0.267 0.0385 0.55 0.238 0.002 0.03 0.4135 0.7488 1686198 ChemDiv3_015935 O=c1cc(nc2SCCCn21)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E08 compound treatment 0.213 -0.0155 -0.22 0.247 0.011 0.18 -0.0259 -0.0899 3043133 ChemDiv3_015936 CCc1ccc(NC(=O)n2ncc3c(C)cccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E09 compound treatment 0.202 -0.0265 -0.38 0.147 -0.089 -1.49 -1.324 -0.8592 3043135 ChemDiv3_015937 CC(Oc1ccccc1)c2nc3ccccc3n2CCOc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E10 compound treatment 0.235 0.00653 0.09 0.284 0.048 0.81 0.6357 0.7839 3043136 ChemDiv3_015938 CN(Cc1ccccc1)c2nnc(NC(=O)NCc3ccccc3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E11 compound treatment 0.23 0.00153 0.02 0.266 0.03 0.5 0.3715 0.7372 3123767 ChemDiv3_015939 N=C1SC2CS(=O)(=O)CC2N1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E12 compound treatment 0.25 0.0215 0.31 0.257 0.021 0.35 0.467 0.9977 3123768 ChemDiv3_015940 CN1C(=O)c2ccccc2Sc3ccc(NC(=O)NCc4ccc(C)cc4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E13 compound treatment 0.249 0.0205 0.29 0.239 0.003 0.05 0.2433 0.8164 3043139 ChemDiv3_015941 CC(C)NC(=O)CCCc1nc(no1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E14 compound treatment 0.257 0.0285 0.41 0.243 0.007 0.12 0.3716 0.8751 3123769 ChemDiv3_015942 CCCNC(=O)Nc1ccc2Sc3ccccc3C(=O)N(CC)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E15 compound treatment 0.257 0.0285 0.41 0.255 0.019 0.32 0.5141 0.9926 3043141 ChemDiv3_015943 CC(C)CCNc1c2CCCc2nc3nncn13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E16 compound treatment 0.225 -0.00347 -0.05 0.284 0.048 0.81 0.5346 0.6623 3123770 ChemDiv3_015944 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NCc4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E17 compound treatment 0.241 0.0125 0.18 0.283 0.047 0.79 0.6845 0.8462 3043143 ChemDiv3_015945 COc1ccc(Nc2cc(nc3nncn23)c4ccccc4)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E18 compound treatment 0.273 0.0445 0.64 0.234 -0.002 -0.03 0.4267 0.6689 3123771 ChemDiv3_015946 CNC(=O)CCC(=O)N1CCOc2ccc(C)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E19 compound treatment 0.272 0.0435 0.62 0.224 -0.012 -0.2 0.2979 0.4552 3123772 ChemDiv3_015947 Fc1ccc(Cn2c(nc3ccccc23)C4CN(CC=C)C(=O)C4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E20 compound treatment 0.235 0.00653 0.09 0.215 -0.021 -0.35 -0.1832 -0.5023 3043146 ChemDiv3_015948 CCc1ccc(cc1)c2cc3c(=O)n(CC(=O)NC4CCCC(C)C4C)nc(C)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E21 compound treatment 0.25 0.0215 0.31 0.237 0.001 0.02 0.2296 0.7445 3123773 ChemDiv3_015949 CCN(Cc1nc(no1)c2ccc(C)cc2)C(=O)Nc3ccccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E22 compound treatment 0.201 -0.0275 -0.39 0.229 -0.007 -0.12 -0.3609 -0.88 3043148 ChemDiv3_015950 CN(Cc1ccccc1)C(=O)Cn2ncn3cccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E23 mock treatment 0.206 -0.0225 -0.32 0.255 0.019 0.32 -0.0018 -0.0039 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 E24 mock treatment 0.208 -0.0205 -0.29 0.219 -0.017 -0.29 -0.4088 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F01 compound treatment 0.214 -0.0145 -0.21 0.21 -0.026 -0.44 -0.4549 -0.9419 3123774 ChemDiv3_015951 COc1ccc(cc1)C2=NS(=O)(=O)N(C)C(=C2)C(=O)N(C)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F02 compound treatment 0.236 0.00753 0.11 0.195 -0.041 -0.69 -0.4104 -0.5892 3123775 ChemDiv3_015952 CCOC(=O)c1ccc(NC(=O)Cc2noc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F03 compound treatment 0.206 -0.0225 -0.32 0.212 -0.024 -0.4 -0.5121 -0.9937 3043150 ChemDiv3_015953 CN1C(=CC(=NS1(=O)=O)c2ccc(F)cc2)C(=O)N3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F04 compound treatment 0.268 0.0395 0.57 0.252 0.016 0.27 0.5897 0.9421 3123776 ChemDiv3_015954 Cc1ccc2onc(CC(=O)NCc3cccc(Cl)c3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F05 compound treatment 0.289 0.0605 0.87 0.246 0.01 0.17 0.7309 0.8288 3123777 ChemDiv3_015955 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F06 compound treatment 0.259 0.0305 0.44 0.258 0.022 0.37 0.5699 0.9965 3043187 ChemDiv3_015956 OCCNC(=O)c1nnc(o1)c2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F07 compound treatment 0.272 0.0435 0.62 0.26 0.024 0.4 0.7251 0.9778 3043189 ChemDiv3_015957 CSc1cccc(c1)n2nnc(C(=O)N)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F08 compound treatment 0.255 0.0265 0.38 0.283 0.047 0.79 0.8261 0.9437 3043191 ChemDiv3_015958 O=C(Cn1ccn(c2ccccc2)c(=O)c1=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F09 compound treatment 0.265 0.0365 0.52 0.269 0.033 0.55 0.7611 0.9996 3043192 ChemDiv3_015959 CCCCN(C)C(=O)c1nn(C)c-2c1CSc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F10 compound treatment 0.303 0.0745 1.07 0.284 0.048 0.81 1.3235 0.9905 3043193 ChemDiv3_015960 Cc1c(sc2nc3CCCCn3c(=O)c12)C(=O)N4CCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F11 compound treatment 0.299 0.0705 1.01 0.248 0.012 0.2 0.8558 0.8319 3043195 ChemDiv3_015961 COc1ccc(cc1)C(=O)Nc2nn3c(CC(C)C)nnc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F12 compound treatment 0.278 0.0495 0.71 0.303 0.067 1.12 1.2961 0.9752 3043196 ChemDiv3_015962 CCOc1ccc(CCNC(=O)c2cccc3C(=O)CCSc23)cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F13 compound treatment 0.272 0.0435 0.62 0.299 0.063 1.06 1.188 0.9681 3123778 ChemDiv3_015963 CNC(=O)c1cc([nH]c1C)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F14 compound treatment 0.242 0.0135 0.19 0.255 0.019 0.32 0.3624 0.9714 3043198 ChemDiv3_015964 CN(C)CCNC(=O)c1nc(no1)c2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F15 compound treatment 0.268 0.0395 0.57 0.265 0.029 0.49 0.744 0.9972 3123779 ChemDiv3_015965 CCc1ccc(NC(=O)CSc2nc3nccnc3c(=O)n2CCC(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F16 compound treatment 0.257 0.0285 0.41 0.274 0.038 0.64 0.7396 0.9767 3043200 ChemDiv3_015966 O=C(NCc1ccccc1)N2CCOc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F17 compound treatment 0.309 0.0805 1.15 0.297 0.061 1.02 1.5385 0.9983 3123780 ChemDiv3_015967 Cn1cc(cc1C(=O)N2CCc3ccccc3C2)S(=O)(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F18 compound treatment 0.284 0.0555 0.79 0.288 0.052 0.87 1.1788 0.9989 3123781 ChemDiv3_015968 CCn1cc(CCCC(=O)NCc2cc(Br)ccc2OC)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F19 compound treatment 0.254 0.0255 0.37 0.271 0.035 0.59 0.6736 0.9738 3043203 ChemDiv3_015969 CCCCN(C)S(=O)(=O)c1ccc2N(CCOc2c1)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F20 compound treatment 0.257 0.0285 0.41 0.225 -0.011 -0.18 0.158 0.3528 3123782 ChemDiv3_015970 CCC(C)NC(=O)c1cc(no1)c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F21 compound treatment 0.286 0.0575 0.82 0.242 0.006 0.1 0.6531 0.7878 3043205 ChemDiv3_015971 CC1CCN(CC1)C(=O)Cc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F22 compound treatment 0.26 0.0315 0.45 0.226 -0.01 -0.17 0.2002 0.4161 3123783 ChemDiv3_015972 Cc1ccc(C)c(c1)N2CCN(CC2)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F23 mock treatment 0.255 0.0265 0.38 0.271 0.035 0.59 0.6837 0.9776 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 F24 mock treatment 0.218 -0.0105 -0.15 0.254 0.018 0.3 0.1077 0.3195 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G01 compound treatment 0.216 -0.0125 -0.18 0.241 0.005 0.08 -0.0668 -0.3388 3043206 ChemDiv3_015973 COc1ccc(cc1)c2noc(CN(C(C)C)C(=O)CN3C(=O)c4ccccc4C3=O)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G02 compound treatment 0.228 -4.69E-4 -0.01 0.277 0.041 0.69 0.4819 0.7002 3123784 ChemDiv3_015974 CCC(O)c1nc2ccccc2n1CCOc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G03 compound treatment 0.267 0.0385 0.55 0.304 0.068 1.14 1.1967 0.9442 3043208 ChemDiv3_015975 O=C(CSc1ccccc1)NCc2nc(no2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G04 compound treatment 0.274 0.0455 0.65 0.245 0.009 0.15 0.5673 0.8486 3123785 ChemDiv3_015976 CCc1ccc(NC(=O)Nc2nnc(s2)N3CCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G05 compound treatment 0.248 0.0195 0.28 0.27 0.034 0.57 0.6011 0.946 3123786 ChemDiv3_015977 COc1ccc(cc1)c2noc(CN3C(=O)c4ccccc4C3=O)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G06 compound treatment 0.242 0.0135 0.19 0.284 0.048 0.81 0.7065 0.8527 3043210 ChemDiv3_015978 CC1CCCCN1C(=O)CCC(=O)n2ncc3cc(C)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G07 compound treatment 0.288 0.0595 0.85 0.175 -0.061 -1.02 -0.1218 -0.0915 3123787 ChemDiv3_015979 CC(C)(C)OC(=O)N1CCC(CC1)c2nc(O)c3nnn(Cc4ccccc4Cl)c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G08 compound treatment 0.254 0.0255 0.37 0.212 -0.024 -0.4 -0.0266 -0.0489 3043213 ChemDiv3_015980 COC(=O)c1ccccc1NC(=O)n2ncc3c(C)cccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G09 compound treatment 0.232 0.00353 0.05 0.182 -0.054 -0.91 -0.6052 -0.6667 3123788 ChemDiv3_015981 CC(Oc1cccc(C)c1)c2nc3ccccc3n2CC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G10 compound treatment 0.261 0.0325 0.47 0.283 0.047 0.79 0.8868 0.9683 3043255 ChemDiv3_015982 CCCN(Cc1cccs1)C(=O)Nc2ccccc2CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G11 compound treatment 0.28 0.0515 0.74 0.235 -0.001 -0.02 0.5093 0.6908 3043257 ChemDiv3_015983 CC(=O)/N=C/1\SC2CS(=O)(=O)CC2N1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G12 compound treatment 0.26 0.0315 0.45 0.219 -0.017 -0.29 0.1172 0.2195 3043258 ChemDiv3_015984 CCCNC(=O)Nc1ccc2Sc3ccccc3C(=O)N(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G13 compound treatment 0.258 0.0295 0.42 0.267 0.031 0.52 0.6666 0.9947 3043260 ChemDiv3_015985 NC(=O)CCCc1nc(no1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G14 compound treatment 0.271 0.0425 0.61 0.244 0.008 0.13 0.5251 0.8429 3043261 ChemDiv3_015986 NC(=O)C1CCN(CC1)C(=O)CSCc2cnn(c2n3cccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G15 compound treatment 0.249 0.0205 0.29 0.221 -0.015 -0.25 0.0296 0.0766 3043263 ChemDiv3_015987 CCN(CC)c1c2CCCc2nc3nncn13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G16 compound treatment 0.256 0.0275 0.39 0.251 0.015 0.25 0.4565 0.9766 3043264 ChemDiv3_015988 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)N4CCN(CC4)c5ccc(Cl)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G17 compound treatment 0.241 0.0125 0.18 0.223 -0.013 -0.22 -0.0275 -0.0975 3123789 ChemDiv3_015989 Fc1ccc(cc1)S(=O)(=O)N2CCC(CC2)c3ccc(=O)n(n3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G18 compound treatment 0.254 0.0255 0.37 0.254 0.018 0.3 0.4719 0.9956 3043266 ChemDiv3_015990 CC1CN(C(=O)CCC(=O)N(C)Cc2ccccc2)c3ccccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G19 compound treatment 0.219 -0.00947 -0.14 0.206 -0.03 -0.5 -0.4518 -0.8665 3123790 ChemDiv3_015991 Cc1ccc(C)c(Cn2ncc3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G20 compound treatment 0.23 0.00153 0.02 0.218 -0.018 -0.3 -0.1981 -0.6541 3123902 ChemDiv3_015992 CCc1ccc(cc1)c2cc3c(=O)n(CC(=O)NC(C)CCc4ccccc4)nc(C)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G21 compound treatment 0.237 0.00853 0.12 0.179 -0.057 -0.96 -0.5902 -0.612 3043268 ChemDiv3_015993 CC(C)N(Cc1nc(no1)c2ccc(C)cc2)C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G22 compound treatment 0.232 0.00353 0.05 0.229 -0.007 -0.12 -0.0474 -0.3703 3123903 ChemDiv3_015994 CCOc1ccc(CCNC(=O)Cn2nc(C)n3cccc3c2=O)cc1OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G23 mock treatment 0.196 -0.0325 -0.46 0.234 -0.002 -0.03 -0.3521 -0.7562 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 G24 mock treatment 0.219 -0.00947 -0.14 0.183 -0.053 -0.89 -0.7248 -0.8055 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H01 compound treatment 0.221 -0.00747 -0.11 0.267 0.031 0.52 0.2924 0.5504 3043270 ChemDiv3_015995 CCC1CCCCN1C(=O)C2=CC(=NS(=O)(=O)N2C)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H02 compound treatment 0.204 -0.0245 -0.35 0.3 0.064 1.07 0.5121 0.4533 3123904 ChemDiv3_015996 Cc1ccc(CCNC(=O)Cc2noc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H03 compound treatment 0.222 -0.00647 -0.09 0.239 0.003 0.05 -0.0298 -0.2831 3123905 ChemDiv3_015997 CN1C(=CC(=NS1(=O)=O)c2ccc(F)cc2)C(=O)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H04 compound treatment 0.242 0.0135 0.19 0.237 0.001 0.02 0.1487 0.7656 3043272 ChemDiv3_015998 CN1CCN(CCNC(=O)Cc2noc3ccc(C)cc23)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H05 compound treatment 0.241 0.0125 0.18 0.308 0.072 1.21 0.9812 0.8032 3123906 ChemDiv3_015999 CN1C(=CC(=NS1(=O)=O)c2cccs2)C(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H06 compound treatment 0.239 0.0105 0.15 0.271 0.035 0.59 0.5219 0.8606 3043274 ChemDiv3_016000 O=C(Cn1ccn(Cc2ccccc2)c(=O)c1=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H07 compound treatment 0.279 0.0505 0.72 0.243 0.007 0.12 0.5942 0.8114 3123907 ChemDiv3_016001 CCOc1ccccc1n2nnc(C(=O)N)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H08 compound treatment 0.258 0.0295 0.42 0.247 0.011 0.18 0.4292 0.9311 3123908 ChemDiv3_016002 Fc1ccc(cc1)C(=O)Cn2ccn(c3ccccc3)c(=O)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H09 compound treatment 0.301 0.0725 1.04 0.224 -0.012 -0.2 0.5912 0.5594 3043276 ChemDiv3_016003 CN(C(=O)c1nn(C)c-2c1CSc3ccccc23)c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H10 compound treatment 0.299 0.0705 1.01 0.287 0.051 0.86 1.3186 0.9967 3123909 ChemDiv3_016004 Cc1c(sc2nc3CCCCn3c(=O)c12)C(=O)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H11 compound treatment 0.263 0.0345 0.49 0.221 -0.015 -0.25 0.1712 0.3089 3043278 ChemDiv3_016005 COc1ccccc1C(=O)Nc2nn3c(nnc3s2)c4ccccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H12 compound treatment 0.277 0.0485 0.69 0.234 -0.002 -0.03 0.4671 0.6721 3123910 ChemDiv3_016006 C=CCN(C(=O)c1cccc2C(=O)CCSc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H13 compound treatment 0.308 0.0795 1.14 0.285 0.049 0.82 1.3859 0.9873 3123911 ChemDiv3_016007 Cc1[nH]c(cc1C(=O)N2CCCCC2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H14 compound treatment 0.304 0.0755 1.08 0.272 0.036 0.6 1.1912 0.9623 3043280 ChemDiv3_016008 O=C(N1CCOCC1)c2nc(no2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H15 compound treatment 0.267 0.0385 0.55 0.304 0.068 1.14 1.1967 0.9442 3123912 ChemDiv3_016009 CC(C)CCn1c(SCc2ccc(F)cc2)nc3nccnc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H16 compound treatment 0.308 0.0795 1.14 0.293 0.057 0.96 1.4809 0.9963 3043331 ChemDiv3_016010 Cc1ccc2OCCN(C(=O)Nc3cc(C)cc(C)c3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H17 compound treatment 0.279 0.0505 0.72 0.254 0.018 0.3 0.7247 0.9251 3043332 ChemDiv3_016011 Cn1cc(cc1C(=O)N2CCCc3ccccc23)S(=O)(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H18 compound treatment 0.241 0.0125 0.18 0.184 -0.052 -0.87 -0.4904 -0.5504 3043333 ChemDiv3_016012 Cc1ccc(Cn2cc(CCCC(=O)N3CCCC3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H19 compound treatment 0.292 0.0635 0.91 0.283 0.047 0.79 1.2004 0.9975 3043335 ChemDiv3_016013 CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)NCCc3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H20 compound treatment 0.272 0.0435 0.62 0.245 0.009 0.15 0.5471 0.8539 3043336 ChemDiv3_016014 CC(C)CNC(=O)c1cc(no1)c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H21 compound treatment 0.29 0.0615 0.88 0.22 -0.016 -0.27 0.4325 0.47 3043338 ChemDiv3_016015 COc1ccccc1CNC(=O)Cc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H22 compound treatment 0.293 0.0645 0.92 0.227 -0.009 -0.15 0.5459 0.5836 3043339 ChemDiv3_016016 CCCCN(C)S(=O)(=O)c1ccc2[nH]c(=O)ccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H23 mock treatment 0.222 -0.00647 -0.09 0.26 0.024 0.4 0.2194 0.5309 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 H24 mock treatment 0.209 -0.0195 -0.28 0.243 0.007 0.12 -0.1138 -0.3766 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I01 compound treatment 0.239 0.0105 0.15 0.261 0.025 0.42 0.4032 0.9044 3123913 ChemDiv3_016017 O=C(NCc1nc(no1)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I02 compound treatment 0.22 -0.00847 -0.12 0.25 0.014 0.23 0.0805 0.3045 3123914 ChemDiv3_016018 CCC1N(CCn2c(C)ccc12)C(=O)Nc3ccc(CC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I03 compound treatment 0.26 0.0315 0.45 0.237 0.001 0.02 0.3308 0.7329 3043341 ChemDiv3_016019 Cc1ccc(cc1)c2noc(CNC(=O)CC3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I04 compound treatment 0.265 0.0365 0.52 0.269 0.033 0.55 0.7611 0.9996 3123915 ChemDiv3_016020 Clc1ccc2cnn(CC(=O)N3CCCCC3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I05 compound treatment 0.245 0.0165 0.24 0.262 0.026 0.44 0.4758 0.9586 3043343 ChemDiv3_016021 CC(C)(C)OC(=O)N1CCN(CC1)c2ncnc3[nH]cnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I06 compound treatment 0.228 -4.69E-4 -0.01 0.25 0.014 0.23 0.1614 0.6867 3123916 ChemDiv3_016022 Cc1oc(nc1CN2C(=O)CN=C(c3ccccc3)c4ccccc24)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I07 compound treatment 0.262 0.0335 0.48 0.266 0.03 0.5 0.6952 0.9997 3123917 ChemDiv3_016023 COc1cccc(Cn2nnc3c(O)nc(nc23)C4CCN(CC4)C(=O)c5ccccc5)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I08 compound treatment 0.257 0.0285 0.41 0.248 0.012 0.2 0.431 0.947 3043346 ChemDiv3_016024 CCc1ccc(CNC(=O)CCC(=O)n2ncc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I09 compound treatment 0.246 0.0175 0.25 0.243 0.007 0.12 0.2604 0.9403 3123918 ChemDiv3_016025 CCC(Oc1cccc(C)c1)c2nc3ccccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I10 compound treatment 0.235 0.00653 0.09 0.272 0.036 0.6 0.4933 0.8068 3043348 ChemDiv3_016026 CCCN(Cc1cccs1)C(=O)Nc2cc(OC)cc(OC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I11 compound treatment 0.298 0.0695 0.99 0.264 0.028 0.47 1.0356 0.9414 3123919 ChemDiv3_016027 CC(C)C(=O)/N=C/1\SC2CS(=O)(=O)CC2N1CCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I12 compound treatment 0.249 0.0205 0.29 0.192 -0.044 -0.74 -0.3145 -0.3958 3123920 ChemDiv3_016028 CC(NC(=O)Nc1ccc2Sc3ccccc3C(=O)N(C)c2c1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I13 compound treatment 0.252 0.0235 0.34 0.286 0.05 0.84 0.8314 0.9195 3043350 ChemDiv3_016029 O=C(CCCc1nc(no1)c2ccccc2)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I14 compound treatment 0.247 0.0185 0.27 0.262 0.026 0.44 0.496 0.9714 3123921 ChemDiv3_016030 O=C(CSCc1cnn(c1n2cccc2)c3ccccc3)N4CCC(CC4)N5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I15 compound treatment 0.238 0.00953 0.14 0.265 0.029 0.49 0.4406 0.8716 3043352 ChemDiv3_016031 CC(C)Nc1cc(nc2nncn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I16 compound treatment 0.241 0.0125 0.18 0.273 0.037 0.62 0.5659 0.8755 3123922 ChemDiv3_016032 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)NCc4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I17 compound treatment 0.256 0.0275 0.39 0.202 -0.034 -0.57 -0.1251 -0.1804 3043354 ChemDiv3_016033 CCCc1ccc(cc1)S(=O)(=O)N2CCC(CC2)c3ccc(=O)n(n3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I18 compound treatment 0.236 0.00753 0.11 0.249 0.013 0.22 0.2305 0.9471 3123923 ChemDiv3_016034 CC1CN(C(=O)CCC(=O)N2CCN(CC2)c3ccccn3)c4ccccc4O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I19 compound treatment 0.278 0.0495 0.71 0.207 -0.029 -0.49 0.1568 0.1824 3123924 ChemDiv3_016035 COc1ccc(cc1OC)C2=Nc3cc(ccc3NC(=N2)c4ccncc4)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I20 compound treatment 0.236 0.00753 0.11 0.243 0.007 0.12 0.1592 0.9991 3043356 ChemDiv3_016036 CCc1ccc(cc1)c2cc3c(=O)n(CC(=O)NCCN4CCOCC4)nc(C)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I21 compound treatment 0.239 0.0105 0.15 0.25 0.014 0.23 0.2727 0.9769 3043415 ChemDiv3_016037 Clc1ccc(cc1)c2noc(CNC(=O)NC3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I22 compound treatment 0.192 -0.0365 -0.52 0.246 0.01 0.17 -0.2502 -0.4565 3043416 ChemDiv3_016038 CC(C(=O)N1CCN(CC1)c2ccccn2)n3ncn4cccc4c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I23 mock treatment 0.184 -0.0445 -0.64 0.243 0.007 0.12 -0.3667 -0.5669 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 I24 mock treatment 0.237 0.00853 0.12 0.208 -0.028 -0.47 -0.246 -0.5067 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J01 compound treatment 0.213 -0.0155 -0.22 0.24 0.004 0.07 -0.109 -0.4713 3043418 ChemDiv3_016039 CCN(CC)C(=O)C1=CC(=NS(=O)(=O)N1C)c2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J02 compound treatment 0.228 -4.69E-4 -0.01 0.239 0.003 0.05 0.0309 0.6076 3043420 ChemDiv3_016040 CC(C)N(Cc1ccccc1)C(=O)Cc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J03 compound treatment 0.24 0.0115 0.16 0.244 0.008 0.13 0.2116 0.9948 3043421 ChemDiv3_016041 CCN(CC)C(=O)C1=CC(=NS(=O)(=O)N1C)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J04 compound treatment 0.246 0.0175 0.25 0.26 0.024 0.4 0.4621 0.974 3043423 ChemDiv3_016042 COc1cc(cc(OC)c1OC)c2cc(NC(=O)Cc3noc4ccc(C)cc34)on2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J05 compound treatment 0.289 0.0605 0.87 0.278 0.042 0.7 1.1107 0.9948 3043424 ChemDiv3_016043 CC(C)CNC(=O)C1=CC(=NS(=O)(=O)N1C)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J06 compound treatment 0.239 0.0105 0.15 0.214 -0.022 -0.37 -0.1546 -0.3876 3043425 ChemDiv3_016044 Cc1ccc(Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J07 compound treatment 0.277 0.0485 0.69 0.285 0.049 0.82 1.0724 0.9964 3123925 ChemDiv3_016045 O=C(NCC1(CCCC1)c2ccccc2)c3noc-4c3COc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J08 compound treatment 0.29 0.0615 0.88 0.269 0.033 0.55 1.014 0.9751 3123926 ChemDiv3_016046 O=C(Cn1ccn(c2ccccc2)c(=O)c1=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J09 compound treatment 0.278 0.0495 0.71 0.291 0.055 0.92 1.1537 0.9915 3043427 ChemDiv3_016047 Cn1nc(C(=O)NC2CCCc3ccccc23)c4CSc5ccccc5-c41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J10 compound treatment 0.246 0.0175 0.25 0.278 0.042 0.7 0.6758 0.9032 3123927 ChemDiv3_016048 CCC(C)NC(=O)c1cccc2C(=O)CCSc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J11 compound treatment 0.282 0.0535 0.77 0.297 0.061 1.02 1.2654 0.9898 3123928 ChemDiv3_016049 COc1cccc(c1)C(=O)Nc2nn3c(nnc3s2)c4ccc(OC)c(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J12 compound treatment 0.282 0.0535 0.77 0.253 0.017 0.29 0.7432 0.9095 3043430 ChemDiv3_016050 CC(C)CCNC(=O)c1cccc2C(=O)CCSc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J13 compound treatment 0.22 -0.00847 -0.12 0.263 0.027 0.45 0.2348 0.5005 3123929 ChemDiv3_016051 CN(Cc1ccco1)C(=O)c2cc([nH]c2C)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J14 compound treatment 0.24 0.0115 0.16 0.274 0.038 0.64 0.5676 0.8616 3043432 ChemDiv3_016052 CC1CCCN(CCCNC(=O)c2nc(no2)c3cccnc3)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J15 compound treatment 0.287 0.0585 0.84 0.234 -0.002 -0.03 0.5683 0.6782 3123930 ChemDiv3_016053 CCC(Sc1nc2nccnc2c(=O)n1Cc3ccc4OCOc4c3)C(=O)NC5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J16 compound treatment 0.286 0.0575 0.82 0.248 0.012 0.2 0.7243 0.8549 3124045 ChemDiv3_016054 CCOC(=O)c1ccc(NC(=O)N2CC(C)Oc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J17 compound treatment 0.278 0.0495 0.71 0.29 0.054 0.91 1.1418 0.9926 3043434 ChemDiv3_016055 Cn1cc(cc1C(=O)N2CCC(Cc3ccccc3)CC2)S(=O)(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J18 compound treatment 0.306 0.0775 1.11 0.253 0.017 0.29 0.9859 0.861 3124046 ChemDiv3_016056 CNC(=O)CCCc1cn(Cc2ccc(C)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J19 compound treatment 0.302 0.0735 1.05 0.222 -0.014 -0.23 0.5776 0.5359 3043436 ChemDiv3_016057 CC1CCCC(C1C)N(C)S(=O)(=O)c2ccc3N(CCOc3c2)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J20 compound treatment 0.266 0.0375 0.54 0.278 0.042 0.7 0.8781 0.991 3124047 ChemDiv3_016058 COc1ccc(CCNC(=O)c2cc(no2)c3ccccc3O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J21 compound treatment 0.256 0.0275 0.39 0.276 0.04 0.67 0.7532 0.9677 3124048 ChemDiv3_016059 CCN(C(=O)Cc1noc2ccccc12)c3cc(C)ccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J22 compound treatment 0.278 0.0495 0.71 0.278 0.042 0.7 0.9994 1.0 3043438 ChemDiv3_016060 CCN(Cc1ccccc1)S(=O)(=O)c2ccc3[nH]c(=O)ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J23 mock treatment 0.283 0.0545 0.78 0.263 0.027 0.45 0.872 0.9666 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 J24 mock treatment 0.23 0.00153 0.02 0.255 0.019 0.32 0.241 0.7539 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K01 compound treatment 0.236 0.00753 0.11 0.21 -0.026 -0.44 -0.2324 -0.517 3124049 ChemDiv3_016061 O=C(NCc1nc(no1)c2ccccc2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K02 compound treatment 0.231 0.00253 0.04 0.254 0.018 0.3 0.2392 0.7862 3043498 ChemDiv3_016062 CC1CC(C)CN(C1)c2nnc(NC(=O)Nc3cc(C)cc(C)c3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K03 compound treatment 0.242 0.0135 0.19 0.259 0.023 0.39 0.4098 0.949 3043499 ChemDiv3_016063 CC(C)(C)CC(=O)NCc1nc(no1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K04 compound treatment 0.3 0.0715 1.02 0.258 0.022 0.37 0.9846 0.9052 3043501 ChemDiv3_016064 Clc1ccc2cnn(CC(=O)NC3CCCC3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K05 compound treatment 0.29 0.0615 0.88 0.256 0.02 0.34 0.8597 0.9127 3043503 ChemDiv3_016065 Cc1ccc(NC(=O)N2CCC(O)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K06 compound treatment 0.238 0.00953 0.14 0.212 -0.024 -0.4 -0.1884 -0.4431 3043504 ChemDiv3_016066 CCOC(=O)C1CCCN(C1)C(=O)CCCC(=O)n2ncc3cc(C)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K07 compound treatment 0.294 0.0655 0.94 0.269 0.033 0.55 1.0544 0.9685 3043506 ChemDiv3_016067 O=c1cc(nc2scc(c3ccccc3)n12)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K08 compound treatment 0.308 0.0795 1.14 0.225 -0.011 -0.18 0.6738 0.5847 3043507 ChemDiv3_016068 CCCC1N(CCn2c(C)ccc12)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K09 compound treatment 0.153 -0.0755 -1.08 0.138 -0.098 -1.64 -1.9264 -0.9791 3124050 ChemDiv3_016069 CCC(Oc1ccccc1)c2nc3ccccc3n2CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K10 compound treatment 0.188 -0.0405 -0.58 0.196 -0.04 -0.67 -0.884 -0.9973 3124051 ChemDiv3_016070 CCc1ccc(CN(Cc2c[nH]nc2c3ccc(OC)cc3)C(=O)Nc4ccc(C)cc4C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K11 compound treatment 0.243 0.0145 0.21 0.278 0.042 0.7 0.6454 0.8782 3043508 ChemDiv3_016071 Cc1ccc(cc1)c2nccnn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K12 compound treatment 0.246 0.0175 0.25 0.206 -0.03 -0.5 -0.1787 -0.3177 3043510 ChemDiv3_016072 CCCCN(CC)C(=O)Nc1ccc2Sc3ccccc3C(=O)N(CC)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K13 compound treatment 0.276 0.0475 0.68 0.232 -0.004 -0.07 0.4333 0.6342 3124052 ChemDiv3_016073 CN(C)C(=O)CCCc1nc(no1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K14 compound treatment 0.279 0.0505 0.72 0.275 0.039 0.65 0.9739 0.9988 3043512 ChemDiv3_016074 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K15 compound treatment 0.276 0.0475 0.68 0.214 -0.022 -0.37 0.2196 0.2839 3124053 ChemDiv3_016075 C(Nc1cc(nc2nncn12)c3ccccc3)C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K16 compound treatment 0.248 0.0195 0.28 0.199 -0.037 -0.62 -0.2416 -0.3548 3124054 ChemDiv3_016076 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)NCCCN4CCN(CC4)c5cc(C)ccc5C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K17 compound treatment 0.218 -0.0105 -0.15 0.269 0.033 0.55 0.2858 0.4981 3043515 ChemDiv3_016077 Clc1cccc(c1)n2nnc(n2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K18 compound treatment 0.259 0.0305 0.44 0.247 0.011 0.18 0.4393 0.9266 3124055 ChemDiv3_016078 CC1CN(C(=O)CCC(=O)NC2CCCC2)c3ccccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K19 compound treatment 0.253 0.0245 0.35 0.232 -0.004 -0.07 0.2006 0.5616 3043517 ChemDiv3_016079 C(Nc1c2CCCc2nc3nncn13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K20 compound treatment 0.264 0.0355 0.51 0.242 0.006 0.1 0.4306 0.8311 3124056 ChemDiv3_016080 O=C(C1CCCN1c2nnc(s2)N3CCCC3=O)N4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K21 compound treatment 0.229 5.31E-4 0.01 0.193 -0.043 -0.72 -0.505 -0.6996 3043519 ChemDiv3_016081 COc1ccc(cc1)c2noc(CNC(=O)Nc3cccc(C)c3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K22 compound treatment 0.257 0.0285 0.41 0.202 -0.034 -0.57 -0.1149 -0.1638 3124057 ChemDiv3_016082 CC(C)NC(=O)C(C)n1ncn2cccc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K23 mock treatment 0.207 -0.0215 -0.31 0.241 0.005 0.08 -0.1578 -0.4957 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 K24 mock treatment 0.25 0.0215 0.31 0.243 0.007 0.12 0.3008 0.9127 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L01 compound treatment 0.253 0.0245 0.35 0.21 -0.026 -0.44 -0.0605 -0.108 3043521 ChemDiv3_016083 COc1ccc(cc1)C2=NS(=O)(=O)N(C)C(=C2)C(=O)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L02 compound treatment 0.209 -0.0195 -0.28 0.301 0.065 1.09 0.5745 0.5103 3124058 ChemDiv3_016084 CCOc1ccc(CCNC(=O)Cc2noc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L03 compound treatment 0.257 0.0285 0.41 0.261 0.025 0.42 0.5853 0.9999 3124059 ChemDiv3_016085 COc1ccc(cc1OC)C2=NS(=O)(=O)N(C)C(=C2)C(=O)N3CCC(C)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L04 compound treatment 0.258 0.0295 0.42 0.236 0.0 0.0 0.2987 0.7071 3043523 ChemDiv3_016086 CCN1CCCC1CNC(=O)c2nnc(Cc3cccc(F)c3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L05 compound treatment 0.25 0.0215 0.31 0.234 -0.002 -0.03 0.194 0.6263 3124060 ChemDiv3_016087 CC1CCCCN1C(=O)Cn2nc(NC(=O)C3=CC(=NS(=O)(=O)N3C)c4ccc(C)cc4)cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L06 compound treatment 0.29 0.0615 0.88 0.208 -0.028 -0.47 0.29 0.2907 3043526 ChemDiv3_016088 Clc1ccc(Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L07 compound treatment 0.274 0.0455 0.65 0.266 0.03 0.5 0.8166 0.9919 3042437 ChemDiv3_016089 CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2noc-3c2COc4ccccc34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L08 compound treatment 0.306 0.0775 1.11 0.309 0.073 1.23 1.6505 0.9988 3042439 ChemDiv3_016090 CCc1ccc(NC(=O)c2n[nH]c-3c2CSc4ccccc34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L09 compound treatment 0.296 0.0675 0.97 0.282 0.046 0.77 1.229 0.9938 3042440 ChemDiv3_016091 Cn1nc(C(=O)Nc2cccnc2)c3CSc4ccccc4-c31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L10 compound treatment 0.265 0.0365 0.52 0.227 -0.009 -0.15 0.2627 0.4829 3042441 ChemDiv3_016092 CC1CCCCN1C(=O)c2cccc3C(=O)CCSc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L11 compound treatment 0.281 0.0525 0.75 0.278 0.042 0.7 1.0298 0.9995 3042443 ChemDiv3_016093 COc1cccc(c1)C(=O)Nc2nn3c(COc4ccccc4)nnc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L12 compound treatment 0.275 0.0465 0.67 0.243 0.007 0.12 0.5537 0.8193 3042444 ChemDiv3_016094 Cc1ccc(CCNC(=O)c2cccc3C(=O)CCSc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L13 compound treatment 0.26 0.0315 0.45 0.233 -0.003 -0.05 0.2833 0.6243 3124061 ChemDiv3_016095 Cc1[nH]c(cc1C(=O)NCCCN2CCN(CC2)C3CCCCC3)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L14 compound treatment 0.259 0.0305 0.44 0.245 0.009 0.15 0.4156 0.8994 3042446 ChemDiv3_016096 CN1CCN(CCNC(=O)c2nc(no2)c3cccnc3)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L15 compound treatment 0.264 0.0355 0.51 0.243 0.007 0.12 0.4424 0.8482 3124062 ChemDiv3_016097 COc1ccc(Cl)cc1NC(=O)CSc2nc3nccnc3c(=O)n2Cc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L16 compound treatment 0.311 0.0825 1.18 0.218 -0.018 -0.3 0.6211 0.5097 3042448 ChemDiv3_016098 CC1CN(C(=O)Nc2ccccc2)c3cc(C)ccc3O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L17 compound treatment 0.276 0.0475 0.68 0.279 0.043 0.72 0.9911 0.9996 3124063 ChemDiv3_016099 CC(C)c1ccc(NC(=O)c2cc(cn2C)S(=O)(=O)N3CCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L18 compound treatment 0.313 0.0845 1.21 0.224 -0.012 -0.2 0.7126 0.5813 3042450 ChemDiv3_016100 CNC(=O)CCCc1cn(Cc2ccccc2Cl)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L19 compound treatment 0.273 0.0445 0.64 0.27 0.034 0.57 0.8539 0.9985 3124064 ChemDiv3_016101 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)Nc4cccc(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L20 compound treatment 0.237 0.00853 0.12 0.241 0.005 0.08 0.1456 0.9833 3124065 ChemDiv3_016102 Oc1ccccc1c2cc(on2)C(=O)NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L21 compound treatment 0.279 0.0505 0.72 0.278 0.042 0.7 1.0095 0.9999 3042453 ChemDiv3_016103 CCN(C(=O)Cc1noc2ccccc12)c3cc(OC)ccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L22 compound treatment 0.295 0.0665 0.95 0.271 0.035 0.59 1.0883 0.9731 3124066 ChemDiv3_016104 OC(=O)c1cc(c2cccc(O)c2)c3c(n[nH]c3n1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L23 mock treatment 0.293 0.0645 0.92 0.242 0.006 0.1 0.7239 0.7796 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 L24 mock treatment 0.253 0.0245 0.35 0.184 -0.052 -0.87 -0.369 -0.3923 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M01 compound treatment 0.295 0.0665 0.95 0.31 0.074 1.24 1.5512 0.9914 3042455 ChemDiv3_016105 O=C(Cc1ccccc1)NCc2nc(no2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M02 compound treatment 0.267 0.0385 0.55 0.266 0.03 0.5 0.7458 0.999 3124067 ChemDiv3_016106 CCc1ccc(NC(=O)Nc2nnc(s2)N(C)Cc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M03 compound treatment 0.288 0.0595 0.85 0.263 0.027 0.45 0.9226 0.9564 3124068 ChemDiv3_016107 O=C(CC(c1ccccc1)c2ccccc2)NCc3nc(no3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M04 compound treatment 0.293 0.0645 0.92 0.274 0.038 0.64 1.1037 0.9837 3042457 ChemDiv3_016108 CC1CCCCN1CCCNC(=O)Cn2ncc3ccc(Cl)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M05 compound treatment 0.262 0.0335 0.48 0.226 -0.01 -0.17 0.2205 0.4339 3124069 ChemDiv3_016109 CC1CCN(CC1)c2nc(Cc3ccc(Cl)cc3Cl)nc4n(C)nnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M06 compound treatment 0.293 0.0645 0.92 0.269 0.033 0.55 1.0443 0.9702 3042459 ChemDiv3_016110 O=C(CCC(=O)n1ncc2ccccc12)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M07 compound treatment 0.282 0.0535 0.77 0.249 0.013 0.22 0.6957 0.8738 3124070 ChemDiv3_016111 CC(C)Cn1c(nc2ccccc12)C(O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M08 compound treatment 0.27 0.0415 0.59 0.271 0.035 0.59 0.8354 1.0 3124071 ChemDiv3_016112 CCCC1N(CCn2c(C)ccc12)C(=O)Nc3cc(Cl)ccc3C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M09 compound treatment 0.299 0.0705 1.01 0.207 -0.029 -0.49 0.3692 0.3296 3042461 ChemDiv3_016113 C=CCc1ccccc1OCc2nc3ccccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M10 compound treatment 0.294 0.0655 0.94 0.258 0.022 0.37 0.9239 0.9171 3124072 ChemDiv3_016114 CC1CCCN(C1)c2nnc(NC(=O)NCc3ccc(C)cc3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M11 compound treatment 0.255 0.0265 0.38 0.263 0.027 0.45 0.5888 0.9961 3042529 ChemDiv3_016115 Clc1ccc(cc1)c2cnnc(n2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M12 compound treatment 0.263 0.0345 0.49 0.24 0.004 0.07 0.3967 0.7959 3124182 ChemDiv3_016116 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)N4CCCCC4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M13 compound treatment 0.275 0.0465 0.67 0.283 0.047 0.79 1.0284 0.9964 3043363 ChemDiv3_016117 COC(=O)c1ccccc1NC(=O)Cn2c(CCC(=O)O)ccc2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M14 compound treatment 0.281 0.0525 0.75 0.234 -0.002 -0.03 0.5076 0.6748 3043365 ChemDiv3_016118 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M15 compound treatment 0.263 0.0345 0.49 0.268 0.032 0.54 0.729 0.9991 3043366 ChemDiv3_016119 C=CCNc1cc(nc2nncn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M16 compound treatment 0.286 0.0575 0.82 0.24 0.004 0.07 0.6294 0.7623 3043368 ChemDiv3_016120 CC1CCCC(NC2=NS(=O)(=O)C(=C2C)c3ccc(C)cc3)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M17 compound treatment 0.274 0.0455 0.65 0.25 0.014 0.23 0.6267 0.9051 3043369 ChemDiv3_016121 c1ccc(cc1)c2nnn(n2)c3cnc4ccccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M18 compound treatment 0.286 0.0575 0.82 0.269 0.033 0.55 0.9735 0.9814 3043371 ChemDiv3_016122 O=C(CCC(=O)N1CCOc2ccccc12)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M19 compound treatment 0.302 0.0735 1.05 0.219 -0.017 -0.29 0.542 0.4973 3124183 ChemDiv3_016123 O=c1c2CN(Cc3ccccc3)CCc2[nH]c4nncn14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M20 compound treatment 0.233 0.00453 0.06 0.247 0.011 0.18 0.1764 0.9014 3043373 ChemDiv3_016124 O=C(NCc1ccccc1)C2CCCN2c3nnc(s3)N4CCCC4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M21 compound treatment 0.261 0.0325 0.47 0.258 0.022 0.37 0.5901 0.9934 3124184 ChemDiv3_016125 COc1ccc(cc1)c2noc(CN(C(C)C)C(=O)Nc3cccc(C)c3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M22 compound treatment 0.282 0.0535 0.77 0.249 0.013 0.22 0.6957 0.8738 3124185 ChemDiv3_016126 CC1CCCCN1C(=O)C2=CC(=NS(=O)(=O)N2C)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M23 mock treatment 0.226 -0.00247 -0.04 0.24 0.004 0.07 0.0225 0.2967 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 M24 mock treatment 0.227 -0.00147 -0.02 0.266 0.03 0.5 0.3412 0.677 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N01 compound treatment 0.248 0.0195 0.28 0.26 0.024 0.4 0.4824 0.984 3043375 ChemDiv3_016127 CCN1CCN(CC1)C(=O)C2=CC(=NS(=O)(=O)N2C)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N02 compound treatment 0.22 -0.00847 -0.12 0.267 0.031 0.52 0.2823 0.5284 3124186 ChemDiv3_016128 CCN1CCN(Cc2ccc(NC(=O)Cc3noc4ccccc34)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N03 compound treatment 0.242 0.0135 0.19 0.297 0.061 1.02 0.8608 0.8261 3043377 ChemDiv3_016129 CN1C(=CC(=NS1(=O)=O)c2ccco2)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N04 compound treatment 0.235 0.00653 0.09 0.292 0.056 0.94 0.7307 0.7736 3124187 ChemDiv3_016130 CCCNC(=O)c1nnc(Cc2ccc(OC)c(OC)c2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N05 compound treatment 0.281 0.0525 0.75 0.321 0.085 1.43 1.5401 0.9551 3043379 ChemDiv3_016131 COC(=O)c1cc(cn1C)S(=O)(=O)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N06 compound treatment 0.263 0.0345 0.49 0.268 0.032 0.54 0.729 0.9991 3043440 ChemDiv3_016132 NS(=O)(=O)c1ccc(CCn2ccn(CC(=O)NCCC3=CCCCC3)c(=O)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N07 compound treatment 0.303 0.0745 1.07 0.287 0.051 0.86 1.3591 0.9941 3043442 ChemDiv3_016133 CSc1cccc(NC(=O)c2noc-3c2CSc4ccccc34)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N08 compound treatment 0.298 0.0695 0.99 0.309 0.073 1.23 1.5696 0.9946 3043443 ChemDiv3_016134 COc1ccc(NC(=O)c2sc3nc4CCCCCn4c(=O)c3c2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N09 compound treatment 0.271 0.0425 0.61 0.257 0.021 0.35 0.6794 0.9663 3043444 ChemDiv3_016135 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3nn(C)c-4c3CSc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N10 compound treatment 0.28 0.0515 0.74 0.303 0.067 1.12 1.3164 0.979 3043446 ChemDiv3_016136 CC1CCN(CC1)C(=O)c2cccc3C(=O)CCSc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N11 compound treatment 0.28 0.0515 0.74 0.292 0.056 0.94 1.1858 0.9928 3043447 ChemDiv3_016137 O=C(Cc1ccccc1)Nc2nn3c(COc4ccccc4)nnc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N12 compound treatment 0.247 0.0185 0.27 0.261 0.025 0.42 0.4841 0.9755 3124188 ChemDiv3_016138 CC1CCCCC1NC(=O)c2cccc3C(=O)CCSc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N13 compound treatment 0.279 0.0505 0.72 0.263 0.027 0.45 0.8315 0.9747 3043450 ChemDiv3_016139 Cc1cccc(Cn2nc(Cc3cccnc3)c4ccccc4c2=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N14 compound treatment 0.273 0.0445 0.64 0.285 0.049 0.82 1.0319 0.992 3124189 ChemDiv3_016140 O=C(C1CCN(CC1)C(=O)N2CCOc3ccccc23)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N15 compound treatment 0.278 0.0495 0.71 0.321 0.085 1.43 1.5098 0.9478 3043451 ChemDiv3_016141 CN(c1cccc(C)c1)S(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N16 compound treatment 0.317 0.0885 1.27 0.289 0.053 0.89 1.5244 0.9851 3042463 ChemDiv3_016142 CCOc1ccccc1NC(=O)N2CCOc3ccc(Cl)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N17 compound treatment 0.297 0.0685 0.98 0.291 0.055 0.92 1.3459 0.9995 3124190 ChemDiv3_016143 CN(C(=O)c1cc(cn1C)S(=O)(=O)N2CCCC2)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N18 compound treatment 0.293 0.0645 0.92 0.256 0.02 0.34 0.89 0.9062 3124191 ChemDiv3_016144 CCN1CCCC1CNC(=O)c2ccc3c(c2)sc4nc(cn43)c5cccc(OC)c5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N19 compound treatment 0.3 0.0715 1.02 0.249 0.013 0.22 0.8778 0.839 3043454 ChemDiv3_016145 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)N(C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N20 compound treatment 0.263 0.0345 0.49 0.29 0.054 0.91 0.9901 0.9593 3124192 ChemDiv3_016146 O=C1COc2cc(ccc2N1)S(=O)(=O)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N21 compound treatment 0.337 0.109 1.55 0.315 0.079 1.33 2.0353 0.9969 3043456 ChemDiv3_016147 Clc1ccc(CCNC(=O)Cc2noc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N22 compound treatment 0.27 0.0415 0.59 0.291 0.055 0.92 1.0728 0.9773 3124193 ChemDiv3_016148 CN1C(C(C(=O)NCCCN2CCCCC2)c3ccccc3C1=O)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N23 mock treatment 0.233 0.00453 0.06 0.23 -0.006 -0.1 -0.0254 -0.2119 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 N24 mock treatment 0.214 -0.0145 -0.21 0.258 0.022 0.37 0.1148 0.2711 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O01 compound treatment 0.264 0.0355 0.51 0.263 0.027 0.45 0.6798 0.9984 3043458 ChemDiv3_016149 COc1ccc(cc1)c2noc(CNC(=O)COc3ccccc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O02 compound treatment 0.254 0.0255 0.37 0.334 0.098 1.64 1.4213 0.8436 3124194 ChemDiv3_016150 Cc1ccc2cnn(CCCC(=O)NCc3ccccc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O03 compound treatment 0.269 0.0405 0.58 0.279 0.043 0.72 0.9203 0.9941 3124195 ChemDiv3_016151 O=C(CCC1CCCC1)NCc2nc(no2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O04 compound treatment 0.225 -0.00347 -0.05 0.269 0.033 0.55 0.3566 0.6412 3043460 ChemDiv3_016152 CC1CCCC(NC(=O)Cn2ncc3c(Cl)cccc23)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O05 compound treatment 0.238 0.00953 0.14 0.269 0.033 0.55 0.488 0.8556 3124196 ChemDiv3_016153 C1CC2CN(CCN2C1)c3ncnc4[nH]cnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O06 compound treatment 0.273 0.0445 0.64 0.283 0.047 0.79 1.0082 0.9944 3124197 ChemDiv3_016154 Cc1ccc2n(ncc2c1)C(=O)CCCC(=O)NC3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O07 compound treatment 0.268 0.0395 0.57 0.271 0.035 0.59 0.8152 0.9998 1544850 ChemDiv3_016155 CC(C)n1c(nc2ccccc12)C(O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O08 compound treatment 0.267 0.0385 0.55 0.278 0.042 0.7 0.8882 0.9926 3124198 ChemDiv3_016156 CCCCN(C)c1nnc(NC(=O)Nc2cccc(C)c2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O09 compound treatment 0.247 0.0185 0.27 0.296 0.06 1.01 0.8995 0.8638 3042464 ChemDiv3_016157 CC(C)n1c(COc2cc(C)ccc2C)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O10 compound treatment 0.273 0.0445 0.64 0.26 0.024 0.4 0.7352 0.9756 3042466 ChemDiv3_016158 Fc1ccc(CN2C(=O)c3ccccc3OC42CCN(CC4)C(=O)NC5CCCC5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O11 compound treatment 0.219 -0.00947 -0.14 0.287 0.051 0.86 0.5095 0.5879 3042467 ChemDiv3_016159 O=C(CCCc1nc(no1)c2ccccc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O12 compound treatment 0.245 0.0165 0.24 0.231 -0.005 -0.08 0.1079 0.4299 3042469 ChemDiv3_016160 CCN1C(=O)c2ccccc2Sc3ccc(NC(=O)NCc4ccccc4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O13 compound treatment 0.263 0.0345 0.49 0.22 -0.016 -0.27 0.1594 0.2835 3042470 ChemDiv3_016161 COc1cccc(c1)c2noc(n2)C(C)Oc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O14 compound treatment 0.281 0.0525 0.75 0.321 0.085 1.43 1.5401 0.9551 3124199 ChemDiv3_016162 O=C(CCSCc1cnn(c1n2cccc2)c3ccccc3)NCc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O15 compound treatment 0.252 0.0235 0.34 0.273 0.037 0.62 0.6771 0.9586 3042472 ChemDiv3_016163 C(Cc1ccccc1)Nc2cc(nc3nncn23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O16 compound treatment 0.267 0.0385 0.55 0.255 0.019 0.32 0.6152 0.9662 3124200 ChemDiv3_016164 CC1CN(CCN1c2cccc(C)c2)C(=O)CCC(=O)N3CCOc4ccc(Cl)cc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O17 compound treatment 0.226 -0.00247 -0.04 0.299 0.063 1.06 0.7227 0.6831 3042474 ChemDiv3_016165 CCc1nonc1NC(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O18 compound treatment 0.23 0.00153 0.02 0.308 0.072 1.21 0.87 0.7198 3124201 ChemDiv3_016166 Clc1ccccc1NC(=O)CCC(=O)N2CCOc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O19 compound treatment 0.24 0.0115 0.16 0.294 0.058 0.97 0.805 0.8153 3042476 ChemDiv3_016167 Cc1cc(N2CCCC(C2)C(=O)O)n3cnnc3n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O20 compound treatment 0.269 0.0405 0.58 0.292 0.056 0.94 1.0746 0.973 3124202 ChemDiv3_016168 CCOc1ccc(NC(=O)C2CCCN2c3nnc(s3)N4CCCC4=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O21 compound treatment 0.202 -0.0265 -0.38 0.306 0.07 1.17 0.5631 0.4561 3042478 ChemDiv3_016169 COc1ccc(cc1OC)c2noc(CN(C(C)C)C(=O)NC3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O22 compound treatment 0.21 -0.0185 -0.26 0.244 0.008 0.13 -0.0919 -0.31 3124203 ChemDiv3_016170 CN1C(=CC(=NS1(=O)=O)c2ccc(C)cc2)C(=O)N3CCc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O23 mock treatment 0.222 -0.00647 -0.09 0.222 -0.014 -0.23 -0.2316 -0.917 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 O24 mock treatment 0.24 0.0115 0.16 0.217 -0.019 -0.32 -0.1089 -0.3032 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P01 compound treatment 0.231 0.00253 0.04 0.261 0.025 0.42 0.3223 0.7653 3124204 ChemDiv3_016171 COc1ccc(cc1)C2=NS(=O)(=O)N(C)C(=C2)C(=O)N3CCC(CC3)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P02 compound treatment 0.238 0.00953 0.14 0.246 0.01 0.17 0.2151 0.9947 3042480 ChemDiv3_016172 CC(NC(=O)Cc1noc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P03 compound treatment 0.236 0.00753 0.11 0.251 0.015 0.25 0.2542 0.9283 3124205 ChemDiv3_016173 CC(C)NC(=O)C1=CC(=NS(=O)(=O)N1C)c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P04 compound treatment 0.26 0.0315 0.45 0.306 0.07 1.17 1.1497 0.9136 3042482 ChemDiv3_016174 COc1ccc(Cc2nnc(o2)C(=O)N3CCN(CC3)c4ccccc4OC)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P05 compound treatment 0.247 0.0185 0.27 0.258 0.022 0.37 0.4485 0.9868 3124206 ChemDiv3_016175 COC(=O)c1cc(cn1C)S(=O)(=O)NC2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P06 compound treatment 0.25 0.0215 0.31 0.277 0.041 0.69 0.7044 0.9343 3124207 ChemDiv3_016176 Cc1ccc(CNC(=O)Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P07 compound treatment 0.274 0.0455 0.65 0.232 -0.004 -0.07 0.413 0.6309 3042484 ChemDiv3_016177 Cc1cccc(CCNC(=O)c2nn(C)c-3c2COc4ccccc34)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P08 compound treatment 0.248 0.0195 0.28 0.28 0.044 0.74 0.7197 0.9116 3124208 ChemDiv3_016178 CN1CCN(CCNC(=O)c2sc3nc4CCCCCn4c(=O)c3c2C)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P09 compound treatment 0.269 0.0405 0.58 0.353 0.117 1.96 1.7985 0.8784 3042487 ChemDiv3_016179 Cn1nc(C(=O)NCCc2ccsc2)c3CSc4ccccc4-c31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P10 compound treatment 0.272 0.0435 0.62 0.274 0.038 0.64 0.8913 0.9999 3124209 ChemDiv3_016180 CCc1ccc(NC(=O)c2cccc3C(=O)CCSc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P11 compound treatment 0.241 0.0125 0.18 0.328 0.092 1.54 1.2186 0.7839 3124210 ChemDiv3_016181 O=C(CCc1ccccc1)Nc2nn3c(nnc3s2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P12 compound treatment 0.273 0.0445 0.64 0.305 0.069 1.16 1.2693 0.9603 3042489 ChemDiv3_016182 O=C(NCc1ccccc1)c2cccc3C(=O)CCSc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P13 compound treatment 0.283 0.0545 0.78 0.325 0.089 1.49 1.6078 0.9541 3042531 ChemDiv3_016183 CCOC(=O)CSc1nc2nccnc2c(=O)n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P14 compound treatment 0.265 0.0365 0.52 0.263 0.027 0.45 0.6899 0.9975 3042533 ChemDiv3_016184 CNC(=O)C1CCN(CC1)C(=O)N2CCOc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P15 compound treatment 0.255 0.0265 0.38 0.312 0.076 1.28 1.1703 0.8794 3042534 ChemDiv3_016185 CN1CCOc2cc(ccc12)S(=O)(=O)NCCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P16 compound treatment 0.245 0.0165 0.24 0.289 0.053 0.89 0.7962 0.865 3042536 ChemDiv3_016186 Cc1cccc(NC(=O)N2CCOc3ccc(Cl)cc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P17 compound treatment 0.269 0.0405 0.58 0.347 0.111 1.86 1.7273 0.8853 3042537 ChemDiv3_016187 Cn1cc(cc1C(=O)NCc2ccccc2)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P18 compound treatment 0.26 0.0315 0.45 0.276 0.04 0.67 0.7936 0.9813 3042538 ChemDiv3_016188 COc1ccc(cc1OC)c2cc(on2)C(=O)NC(C)(C)CO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P19 compound treatment 0.284 0.0555 0.79 0.251 0.015 0.25 0.7397 0.8877 3042540 ChemDiv3_016189 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)NCc4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P20 compound treatment 0.244 0.0155 0.22 0.276 0.04 0.67 0.6318 0.8934 3042541 ChemDiv3_016190 O=C1COc2cc(ccc2N1)S(=O)(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P21 compound treatment 0.287 0.0585 0.84 0.324 0.088 1.48 1.6364 0.9638 3124324 ChemDiv3_016191 CCc1cccc(NC(=O)Cc2noc3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P22 compound treatment 0.241 0.0125 0.18 0.277 0.041 0.69 0.6133 0.8625 3124325 ChemDiv3_016192 CCC(C)NC(=O)C1C(N(CCOC)C(=O)c2ccccc12)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P23 mock treatment 0.263 0.0345 0.49 0.254 0.018 0.3 0.5629 0.9722 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2046 P24 mock treatment 0.233 0.00453 0.06 0.211 -0.025 -0.42 -0.2509 -0.5909 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A01 compound treatment 0.269 0.0182 0.26 0.235 0.0195 0.33 0.4154 0.9935 3124326 ChemDiv3_016193 COCCN1C(C(C(=O)NCC2CCCO2)c3ccccc3C1=O)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A02 compound treatment 0.271 0.0202 0.29 0.247 0.0315 0.53 0.578 0.9595 3042544 ChemDiv3_016194 O=C(CCn1c(=O)c2cccn2c3cccnc13)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A03 compound treatment 0.234 -0.0168 -0.24 0.25 0.0345 0.58 0.2394 0.3818 3042545 ChemDiv3_016195 COc1cccc(c1)n2cc(C(=O)N(C)c3ccccc3)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A04 compound treatment 0.308 0.0572 0.82 0.217 0.0015 0.03 0.5962 0.7285 3124327 ChemDiv3_016196 CCc1ccccc1NC(=O)CCC(=O)N2CCSc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A05 compound treatment 0.216 -0.0348 -0.5 0.241 0.0255 0.43 -0.0495 -0.0753 3124328 ChemDiv3_016197 Cc1cccc(CCNC(=O)C2CCN(CC2)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A06 compound treatment 0.271 0.0202 0.29 0.213 -0.0025 -0.04 0.1745 0.5981 3042547 ChemDiv3_016198 CCn1cc(CCC(=O)NC2CCCC(C)C2C)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A07 compound treatment 0.259 0.00819 0.12 0.246 0.0305 0.51 0.4448 0.847 3124329 ChemDiv3_016199 Fc1ccc(NC(=O)Nc2noc-3c2COc4ccccc34)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A08 compound treatment 0.221 -0.0298 -0.43 0.241 0.0255 0.43 0.0011 0.0018 3042549 ChemDiv3_016200 Fc1ccc(Cn2cc(CCC(=O)N3CCOCC3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A09 compound treatment 0.259 0.00819 0.12 0.243 0.0275 0.46 0.4092 0.8593 3124330 ChemDiv3_016201 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NCCN4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A10 compound treatment 0.247 -0.00381 -0.05 0.255 0.0395 0.66 0.4302 0.6468 3124331 ChemDiv3_016202 COc1ccc(cc1)c2noc(CC(=O)N3CCC(C)CC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A11 compound treatment 0.272 0.0212 0.3 0.223 0.0075 0.13 0.3033 0.9243 3042552 ChemDiv3_016203 Cc1cc2NC(=O)COc2cc1S(=O)(=O)CCC(=O)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A12 compound treatment 0.234 -0.0168 -0.24 0.227 0.0115 0.19 -0.0336 -0.1088 3124332 ChemDiv3_016204 Cc1nc2ccc(cc2s1)S(=O)(=O)CCC(=O)N3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A13 compound treatment 0.25 -8.12E-4 -0.01 0.22 0.0045 0.08 0.0452 0.5913 3124333 ChemDiv3_016205 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)CCC(=O)N(C)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A14 compound treatment 0.234 -0.0168 -0.24 0.222 0.0065 0.11 -0.0929 -0.3518 3042554 ChemDiv3_016206 CN(C1CCCCC1)S(=O)(=O)c2c(C)nc3sccn3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A15 compound treatment 0.293 0.0422 0.6 0.225 0.0095 0.16 0.5394 0.8643 3042555 ChemDiv3_016207 CCN(c1cccc(C)c1)S(=O)(=O)c2c[nH]c(c2)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A16 compound treatment 0.299 0.0482 0.69 0.198 -0.0175 -0.29 0.2797 0.3733 3042595 ChemDiv3_016208 O=C(NCc1noc2ccccc12)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A17 compound treatment 0.211 -0.0398 -0.57 0.207 -0.0085 -0.14 -0.5036 -0.8577 3042596 ChemDiv3_016209 Cc1ccc(NC(=O)C2CCCN2S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A18 compound treatment 0.245 -0.00581 -0.08 0.224 0.0085 0.14 0.0421 0.2549 3042598 ChemDiv3_016210 O=C(NCc1noc2ccccc12)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A19 compound treatment 0.268 0.0172 0.25 0.203 -0.0125 -0.21 0.0255 0.0789 3042600 ChemDiv3_016211 O=C(NCCCc1ccccc1)C2CCCN(C2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A20 compound treatment 0.223 -0.0278 -0.4 0.215 -5.0E-4 -0.01 -0.2872 -0.7219 3042601 ChemDiv3_016212 CCc1cccc(NC(=O)C2CCCN2S(=O)(=O)c3ccc4N(C(C)Cc4c3)C(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A21 compound treatment 0.301 0.0502 0.72 0.242 0.0265 0.44 0.8221 0.9735 3042603 ChemDiv3_016213 Cc1c(oc2ccc3OC(C)(C)CC(=O)c3c12)C(=O)Nc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A22 compound treatment 0.226 -0.0248 -0.35 0.216 5.0E-4 0.01 -0.245 -0.6902 3124334 ChemDiv3_016214 CC1CCN(CC1)S(=O)(=O)c2ccc3N(CC(=O)Nc4nc(C)cs4)C(=O)COc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A23 mock treatment 0.246 -0.00481 -0.07 0.218 0.0025 0.04 -0.019 -0.2357 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 A24 mock treatment 0.194 -0.0568 -0.81 0.189 -0.0265 -0.44 -0.8891 -0.9598 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B01 compound treatment 0.319 0.0682 0.98 0.257 0.0415 0.7 1.1822 0.9864 3124335 ChemDiv3_016215 Cc1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B02 compound treatment 0.3 0.0492 0.7 0.239 0.0235 0.39 0.7764 0.9626 3042605 ChemDiv3_016216 Cc1cc(NC(=O)Nc2cn(C)c(=O)c3ccccc23)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B03 compound treatment 0.283 0.0322 0.46 0.231 0.0155 0.26 0.5095 0.9635 3124336 ChemDiv3_016217 CC(C)CCn1c(=O)c2sccc2n3c(CCCC(=O)N4CCCC4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B04 compound treatment 0.283 0.0322 0.46 0.229 0.0135 0.23 0.4858 0.9467 3042607 ChemDiv3_016218 Cn1cc(NC(=O)NCCc2ccsc2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B05 compound treatment 0.317 0.0662 0.95 0.261 0.0455 0.76 1.2094 0.9943 3124337 ChemDiv3_016219 CCn1cc(c(=O)c2cc(F)c(cc12)N3CCOCC3)S(=O)(=O)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B06 compound treatment 0.324 0.0732 1.05 0.257 0.0415 0.7 1.2328 0.9804 3042609 ChemDiv3_016220 Clc1ccc(CC(=O)Nc2ccc(cc2)c3nnc4CCCCCn34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B07 compound treatment 0.252 0.00119 0.02 0.234 0.0185 0.31 0.2316 0.7447 3124338 ChemDiv3_016221 CCCNC(=O)C1CCCN(C1)c2nn3cc(nc3s2)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B08 compound treatment 0.253 0.00219 0.03 0.259 0.0435 0.73 0.5384 0.7367 3124339 ChemDiv3_016222 CN(C(=O)CCS(=O)(=O)c1ccc2N(CCc2c1)C(=O)C)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B09 compound treatment 0.273 0.0222 0.32 0.259 0.0435 0.73 0.7407 0.9304 3042612 ChemDiv3_016223 CCOC(=O)c1cccc(NC(=O)N2CCC(CN3CCCCC3)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B10 compound treatment 0.361 0.11 1.58 0.235 0.0195 0.33 1.3459 0.8361 3124340 ChemDiv3_016224 CN(C1CCCCC1)C(=O)c2nc(c3ccc(Cl)cc3)n4CCCCCc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B11 compound treatment 0.375 0.124 1.78 0.247 0.0315 0.53 1.6299 0.8794 3042613 ChemDiv3_016225 COc1cc(OC)c(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B12 compound treatment 0.362 0.111 1.59 0.248 0.0325 0.55 1.5103 0.8983 3124341 ChemDiv3_016226 Clc1ccccc1CNC(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B13 compound treatment 0.408 0.157 2.25 0.227 0.0115 0.19 1.7263 0.765 3124342 ChemDiv3_016227 CCN1CCC(CC1)N(Cc2cccc(OC)c2)C(=O)Nc3ccc(CC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B14 compound treatment 0.442 0.191 2.73 0.231 0.0155 0.26 2.1177 0.7709 3042616 ChemDiv3_016228 CCc1ccc(NC(=O)c2cnc(SC)nc2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B15 compound treatment 0.447 0.196 2.81 0.249 0.0335 0.56 2.3819 0.8322 3042663 ChemDiv3_016229 CCN(Cc1ccccc1)C(=O)Cn2c(SCc3ccc(F)cc3)nc4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B16 compound treatment 0.473 0.222 3.18 0.239 0.0235 0.39 2.5262 0.7888 3042665 ChemDiv3_016230 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B17 compound treatment 0.419 0.168 2.41 0.247 0.0315 0.53 2.0749 0.8424 3042666 ChemDiv3_016231 Cc1ccc2Oc3ncccc3C(=O)N(CC(=O)N4CCOCC4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B18 compound treatment 0.426 0.175 2.51 0.232 0.0165 0.28 1.9677 0.7805 3042668 ChemDiv3_016232 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)NCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B19 compound treatment 0.441 0.19 2.72 0.206 -0.0095 -0.16 1.8109 0.6645 3042669 ChemDiv3_016233 O=S(=O)(N1CCCc2ccccc12)c3ccc4[nH]c5CCCCc5c4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B20 compound treatment 0.396 0.145 2.08 0.227 0.0115 0.19 1.6049 0.7695 3042671 ChemDiv3_016234 O=C1N(CCc2ccc(cc2)S(=O)(=O)NCCc3ccccc3)C(=O)c4ncccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B21 compound treatment 0.333 0.0822 1.18 0.234 0.0185 0.31 1.0508 0.8642 3124343 ChemDiv3_016235 CSc1cccc(NC(=O)CC(C)S(=O)(=O)c2ccc3NC(=O)COc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B22 compound treatment 0.22 -0.0308 -0.44 0.235 0.0195 0.33 -0.0802 -0.1461 3042672 ChemDiv3_016236 O=C1N(Cc2ccc(cc2)S(=O)(=O)N3CCCCC3)C(=O)c4ncccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B23 mock treatment 0.307 0.0562 0.8 0.251 0.0355 0.6 0.9896 0.9892 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 B24 mock treatment 0.261 0.0102 0.15 0.219 0.0035 0.06 0.1446 0.9202 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C01 compound treatment 0.25 -8.12E-4 -0.01 0.243 0.0275 0.46 0.3182 0.6891 3124344 ChemDiv3_016237 COCCN1C(C(C(=O)Nc2ccc(cc2)C(=O)OC)c3ccccc3C1=O)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C02 compound treatment 0.289 0.0382 0.55 0.212 -0.0035 -0.06 0.3447 0.6274 3042674 ChemDiv3_016238 O=C(CCn1c(=O)c2cccn2c3cccnc13)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C03 compound treatment 0.341 0.0902 1.29 0.053 -0.163 -2.73 -1.0164 -0.3369 3124345 ChemDiv3_016239 CCOc1ccccc1CNC(=O)c2cn(c3cccc(OC)c3)c(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C04 compound treatment 0.235 -0.0158 -0.23 0.042 -0.173 -2.91 -2.219 -0.7597 3124346 ChemDiv3_016240 O=C(CCC(=O)N1CCSc2ccccc12)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C05 compound treatment 0.38 0.129 1.85 0.219 0.0035 0.06 1.3482 0.7292 3042677 ChemDiv3_016241 CC(=O)N1CCSc2cc(ccc12)S(=O)(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C06 compound treatment 0.288 0.0372 0.53 0.09 -0.126 -2.11 -1.1133 -0.5125 3124347 ChemDiv3_016242 CCOc1ccccc1CNC(=O)CCc2cn(CC)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C07 compound treatment 0.096 -0.155 -2.21 0.099 -0.117 -1.96 -2.9484 -0.9981 3042679 ChemDiv3_016243 COc1ccccc1CNC(=O)Nc2noc-3c2COc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C08 compound treatment 0.254 0.00319 0.05 0.256 0.0405 0.68 0.5129 0.7528 3124348 ChemDiv3_016244 Fc1ccc(Cn2cc(CCC(=O)NC3CCCC3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C09 compound treatment 0.253 0.00219 0.03 0.265 0.0495 0.83 0.6096 0.7332 3124349 ChemDiv3_016245 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3noc-4c3COc5ccc(C)cc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C10 compound treatment 0.275 0.0242 0.35 0.205 -0.0105 -0.18 0.12 0.3091 3042682 ChemDiv3_016246 CCN(CC)C(=O)Cc1nc(no1)c2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C11 compound treatment 0.427 0.176 2.52 0.045 -0.171 -2.86 -0.2415 -0.0633 3124459 ChemDiv3_016247 Clc1ccccc1CNC(=O)CCS(=O)(=O)c2ccc3NC(=O)COc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C12 compound treatment 0.443 0.192 2.75 0.243 0.0275 0.46 2.2702 0.8144 3042683 ChemDiv3_016248 CSc1cccc(NC(=O)CCS(=O)(=O)c2ccc3nc(C)sc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C13 compound treatment 0.4 0.149 2.13 0.215 -5.0E-4 -0.01 1.503 0.7043 3124460 ChemDiv3_016249 COC(=O)c1cc(c[nH]1)S(=O)(=O)Nc2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C14 compound treatment 0.249 -0.00181 -0.03 0.239 0.0235 0.39 0.2606 0.6592 3042685 ChemDiv3_016250 Cc1nc2sccn2c(=O)c1S(=O)(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C15 compound treatment 0.312 0.0612 0.88 0.239 0.0235 0.39 0.8978 0.9352 3124461 ChemDiv3_016251 COC(=O)c1cc(c[nH]1)S(=O)(=O)N(C)C2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C16 compound treatment 0.29 0.0392 0.56 0.236 0.0205 0.34 0.6396 0.9725 3042687 ChemDiv3_016252 CN(C(=O)NCc1noc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C17 compound treatment 0.446 0.195 2.79 0.23 0.0145 0.24 2.1463 0.7658 3124462 ChemDiv3_016253 CN(CC(=O)NCc1ccccc1)S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C18 compound treatment 0.368 0.117 1.68 0.229 0.0135 0.23 1.3455 0.7955 3124463 ChemDiv3_016254 Cc1nn(c2ccc(C)cc2)c3nc(cc(C)c13)C(=O)NCc4ccc(CN5CCOCC5)o4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C19 compound treatment 0.486 0.235 3.36 0.21 -0.0055 -0.09 2.3135 0.6874 3124464 ChemDiv3_016255 COc1ccc2c(CNCC3CCCO3)c(C(=O)O)n(Cc4ccc(C)cc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C20 compound treatment 0.383 0.132 1.89 0.21 -0.0055 -0.09 1.2717 0.6718 3043406 ChemDiv3_016256 CC(C)C(NS(=O)(=O)c1ccc2N(C(C)Cc2c1)C(=O)C)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C21 compound treatment 0.275 0.0242 0.35 0.224 0.0085 0.14 0.3455 0.9233 3124465 ChemDiv3_016257 O=C(CN1C(=O)C(Oc2cccnc12)c3ccccc3)NCCCN4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C22 compound treatment 0.33 0.0792 1.13 0.201 -0.0145 -0.24 0.6288 0.5428 3043410 ChemDiv3_016258 CC1CCN(CC1)S(=O)(=O)c2ccc3N(CC(=O)NCc4ccc(C)cc4)C(=O)COc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C23 mock treatment 0.278 0.0272 0.39 0.231 0.0155 0.26 0.4589 0.9809 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 C24 mock treatment 0.213 -0.0378 -0.54 0.185 -0.0305 -0.51 -0.7444 -0.9996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D01 compound treatment 0.278 0.0272 0.39 0.21 -0.0055 -0.09 0.2097 0.5247 3124466 ChemDiv3_016259 CCCNC(=O)CCc1nnc2ccc(nn12)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D02 compound treatment 0.232 -0.0188 -0.27 0.251 0.0355 0.6 0.231 0.3534 3043478 ChemDiv3_016260 Cn1cc(NC(=O)Nc2ccccc2F)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D03 compound treatment 0.424 0.173 2.48 0.247 0.0315 0.53 2.1255 0.8391 3124467 ChemDiv3_016261 COc1ccc(cc1)c2noc(n2)N3CCCC(C3)C(=O)NCCc4ccc(OC)c(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D04 compound treatment 0.455 0.204 2.92 0.305 0.0895 1.5 3.1274 0.9522 3043482 ChemDiv3_016262 CC1CCN(Cc2ccc(NC(=O)Nc3cn(C)c(=O)c4ccccc34)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D05 compound treatment 0.472 0.221 3.16 0.293 0.0775 1.3 3.1569 0.9229 3124468 ChemDiv3_016263 CCCn1cc(c(=O)c2cc(F)c(cc12)N3CCN(CC)CC3)S(=O)(=O)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D06 compound treatment 0.439 0.188 2.69 0.267 0.0515 0.86 2.5146 0.8894 3043488 ChemDiv3_016264 O=C(CCC1CCCC1)Nc2ccc(cc2)c3nnc4CCCCCn34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D07 compound treatment 0.376 0.125 1.79 0.269 0.0535 0.9 1.9011 0.9491 3124469 ChemDiv3_016265 CCC1CN(C(=O)Nc2ccc(CC)cc2)c3ccccc3S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D08 compound treatment 0.389 0.138 1.98 0.299 0.0835 1.4 2.3886 0.9858 3124470 ChemDiv3_016266 CC(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3ccc4NC(=O)C(C)Sc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D09 compound treatment 0.391 0.14 2.01 0.318 0.102 1.72 2.6344 0.9971 3043493 ChemDiv3_016267 O=C(NCc1ccccc1)N2CCC(CN3CCCCC3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D10 compound treatment 0.366 0.115 1.65 0.362 0.146 2.46 2.9037 0.981 3124471 ChemDiv3_016268 Clc1ccc(cc1)c2nc(C(=O)N3CCCCCC3)c4CCCCCn24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D11 compound treatment 0.477 0.226 3.24 0.407 0.192 3.21 4.5605 1.0 3043497 ChemDiv3_016269 Cc1cccc(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D12 compound treatment 0.463 0.212 3.04 0.412 0.197 3.3 4.4782 0.9991 3042416 ChemDiv3_016270 CC1CCCN(CCCNC(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D13 compound treatment 0.528 0.277 3.96 0.348 0.133 2.22 4.3761 0.9626 3042419 ChemDiv3_016271 CCN1CCC(CC1)N(Cc2ccc(F)cc2)C(=O)Nc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D14 compound treatment 0.46 0.209 2.99 0.398 0.183 3.06 4.2817 0.9999 3042422 ChemDiv3_016272 CSc1ncc(C(=O)NCCc2ccccc2)c(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D15 compound treatment 0.541 0.29 4.15 0.397 0.181 3.05 5.0891 0.9884 3124472 ChemDiv3_016273 COc1ccc(CCNC(=O)Cn2c(SCc3ccc(C)cc3)nc4cccnc24)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D16 compound treatment 0.417 0.166 2.38 0.459 0.243 4.09 4.5707 0.9668 3042426 ChemDiv3_016274 CCN(c1cccc(C)c1)S(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D17 compound treatment 0.557 0.306 4.38 0.402 0.187 3.13 5.3102 0.9864 3124473 ChemDiv3_016275 CNC(=O)CN1C(=O)c2cccnc2Oc3ccc(Cl)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D18 compound treatment 0.507 0.256 3.66 0.338 0.123 2.06 4.045 0.9627 3124474 ChemDiv3_016276 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D19 compound treatment 0.548 0.297 4.25 0.349 0.134 2.24 4.5902 0.9552 3042431 ChemDiv3_016277 CC(C)CCNS(=O)(=O)c1ccc2[nH]c3CCCCc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D20 compound treatment 0.449 0.198 2.83 0.274 0.0585 0.98 2.6988 0.8996 3124475 ChemDiv3_016278 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(CCN2C(=O)c3cccnc3C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D21 compound treatment 0.405 0.154 2.21 0.213 -0.0025 -0.04 1.5298 0.6935 3042509 ChemDiv3_016279 CCOC(=O)c1cc(C)n(c1C)c2ccc(cc2)C(=O)NC3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D22 compound treatment 0.436 0.185 2.65 0.247 0.0315 0.53 2.2469 0.8318 3124476 ChemDiv3_016280 Cc1ccc(cc1)n2c(=O)n(CC(=O)N)c3c4cc(C)ccc4n(C)c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D23 mock treatment 0.278 0.0272 0.39 0.234 0.0185 0.31 0.4945 0.9938 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 D24 mock treatment 0.244 -0.00681 -0.1 0.192 -0.0235 -0.39 -0.3478 -0.8561 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E01 compound treatment 0.255 0.00419 0.06 0.213 -0.0025 -0.04 0.0127 0.1734 3124477 ChemDiv3_016281 CCN1CCCC1CNC(=O)C2C(N(CC(C)C)C(=O)c3ccccc23)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E02 compound treatment 0.252 0.00119 0.02 0.211 -0.0045 -0.08 -0.0414 -0.5347 3042513 ChemDiv3_016282 CCCNC(=O)CCn1c(=O)c2cccn2c3cccnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E03 compound treatment 0.475 0.224 3.21 0.208 -0.0075 -0.13 2.1785 0.6788 3042515 ChemDiv3_016283 COc1cccc(c1)n2cc(C(=O)NC3CCCC3)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E04 compound treatment 0.462 0.211 3.02 0.198 -0.0175 -0.29 1.9283 0.6354 3124478 ChemDiv3_016284 CSc1ncc(C(=O)O)c(n1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E05 compound treatment 0.479 0.228 3.26 0.266 0.0505 0.85 2.9073 0.8621 3124479 ChemDiv3_016285 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E06 compound treatment 0.311 0.0602 0.86 0.285 0.0695 1.17 1.4336 0.9888 3042523 ChemDiv3_016286 Cc1ccc(NC(=O)CCc2cn(Cc3ccc(Cl)cc3)c4ccccc24)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E07 compound treatment 0.279 0.0282 0.4 0.358 0.142 2.39 1.9763 0.8148 3124480 ChemDiv3_016287 COc1cccc(c1)N2CCN(CC2)S(=O)(=O)c3cc4OCCN(C)c4cc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E08 compound treatment 0.411 0.16 2.29 0.359 0.143 2.41 3.3232 0.9997 3124481 ChemDiv3_016288 Fc1ccc(Cn2cc(CCC(=O)NCC3CCCO3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E09 compound treatment 0.39 0.139 1.99 0.359 0.143 2.41 3.1108 0.9955 3042528 ChemDiv3_016289 COCCN(Cc1ccco1)C(=O)c2noc-3c2COc4ccc(C)cc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E10 compound treatment 0.533 0.282 4.04 0.382 0.167 2.79 4.8301 0.9839 3124482 ChemDiv3_016290 COc1ccc(cc1)c2noc(CC(=O)NCCC(C)C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E11 compound treatment 0.534 0.283 4.05 0.384 0.169 2.83 4.864 0.9846 3042577 ChemDiv3_016291 O=C(CCS(=O)(=O)c1ccc2NC(=O)COc2c1)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E12 compound treatment 0.521 0.27 3.86 0.381 0.166 2.78 4.6969 0.9869 3124483 ChemDiv3_016292 Cc1nc2ccc(cc2s1)S(=O)(=O)CCC(=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E13 compound treatment 0.518 0.267 3.82 0.385 0.17 2.84 4.714 0.9894 3124484 ChemDiv3_016293 CCC(C)NC(=O)C1CCCN1S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E14 compound treatment 0.532 0.281 4.02 0.353 0.138 2.31 4.4759 0.9652 3042580 ChemDiv3_016294 Cc1nc2sccn2c(=O)c1S(=O)(=O)Nc3ccc4OCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E15 compound treatment 0.495 0.244 3.49 0.368 0.153 2.56 4.2797 0.9883 3042582 ChemDiv3_016295 CCCNS(=O)(=O)c1c[nH]c(c1)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E16 compound treatment 0.499 0.248 3.55 0.323 0.108 1.8 3.786 0.9507 3124485 ChemDiv3_016296 Cc1cccc(CN2CCC(CNC(=O)NCc3noc4ccccc34)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E17 compound treatment 0.46 0.209 2.99 0.401 0.186 3.11 4.3173 0.9998 3042589 ChemDiv3_016297 COC(=O)c1cc(c[nH]1)S(=O)(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E18 compound treatment 0.433 0.182 2.61 0.362 0.146 2.46 3.5814 0.9996 3124594 ChemDiv3_016298 COc1ccc(NC(=O)NCc2noc3ccc(C)cc23)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E19 compound treatment 0.475 0.224 3.21 0.383 0.168 2.81 4.2554 0.9978 3124595 ChemDiv3_016299 CCn1c(C(=O)O)c(CNCc2ccccc2)c3ccc(OC)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E20 compound treatment 0.386 0.135 1.93 0.324 0.109 1.82 2.655 0.9996 3042593 ChemDiv3_016300 Cc1ccc(cc1)S(=O)(=O)c2c(O)c3ccc(cc3[nH]c2=O)C(=O)NCc4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E21 compound treatment 0.422 0.171 2.45 0.25 0.0345 0.58 2.1409 0.8509 3124596 ChemDiv3_016301 CCOC(=O)C1CCN(CC1)C(=O)CCN2C(=O)c3ccccc3Sc4ncccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E22 compound treatment 0.406 0.155 2.22 0.198 -0.0175 -0.29 1.3619 0.6082 3042635 ChemDiv3_016302 O=C(CN1C(=O)CSc2cc(ccc12)S(=O)(=O)N3CCCC3)NC4CCCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E23 mock treatment 0.254 0.00319 0.05 0.193 -0.0225 -0.38 -0.2348 -0.6173 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 E24 mock treatment 0.212 -0.0388 -0.56 0.202 -0.0135 -0.23 -0.5528 -0.9219 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F01 compound treatment 0.253 0.00219 0.03 0.218 0.0025 0.04 0.0518 0.9896 3124597 ChemDiv3_016303 CN1CCN(CC1)c2ccc3nnc(CCC(=O)Nc4nccs4)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F02 compound treatment 0.287 0.0362 0.52 0.235 0.0195 0.33 0.5974 0.9756 3042639 ChemDiv3_016304 COc1cccc(NC(=O)Nc2cn(C)c(=O)c3ccccc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F03 compound treatment 0.469 0.218 3.12 0.242 0.0265 0.44 2.5213 0.7998 3124598 ChemDiv3_016305 COc1ccc(cc1)c2noc(n2)N3CCCC(C3)C(=O)NCCCN4CCC(C)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F04 compound treatment 0.469 0.218 3.12 0.253 0.0375 0.63 2.6519 0.8329 3124599 ChemDiv3_016306 CN(C1CCCCC1)c2ncnc3n4CCCCCc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F05 compound treatment 0.36 0.109 1.56 0.241 0.0255 0.43 1.407 0.8688 3042646 ChemDiv3_016307 CCNC(=O)C1CCN(CC1)c2nn3cc(nc3s2)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F06 compound treatment 0.421 0.17 2.43 0.319 0.103 1.74 2.9497 0.9863 1594579 ChemDiv3_016308 COc1ccc(CC(=O)Nc2ccc(cc2)c3nnc4CCCCCn34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F07 compound treatment 0.467 0.216 3.09 0.376 0.161 2.69 4.0914 0.9976 3124600 ChemDiv3_016309 CCC1CN(C(=O)NCc2ccc(C)cc2)c3ccccc3S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F08 compound treatment 0.453 0.202 2.89 0.395 0.179 3.01 4.1753 0.9998 3042650 ChemDiv3_016310 Cc1cc(C)n(n1)c2nc3cc(Cl)ccc3nc2NCc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F09 compound treatment 0.506 0.255 3.65 0.438 0.223 3.73 5.2217 0.9999 3124601 ChemDiv3_016311 CC1CCN(CC2CCN(CC2)C(=O)Nc3ccc(Br)c(C)c3)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F10 compound treatment 0.426 0.175 2.51 0.375 0.16 2.68 3.6648 0.9995 3124602 ChemDiv3_016312 CCN(Cc1ccccc1)C(=O)c2nc(c3ccc(Cl)cc3)n4CCCCCc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F11 compound treatment 0.564 0.313 4.48 0.432 0.217 3.63 5.7371 0.9946 3124603 ChemDiv3_016313 CCOC(=O)Cc1ccc(NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F12 compound treatment 0.514 0.263 3.76 0.444 0.229 3.84 5.3738 1.0 3042656 ChemDiv3_016314 CCOc1ccccc1N(CC)C(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F13 compound treatment 0.519 0.268 3.84 0.406 0.191 3.2 4.9734 0.9959 3124604 ChemDiv3_016315 O=C(CSc1nc2cccnc2[nH]1)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F14 compound treatment 0.486 0.235 3.36 0.439 0.224 3.75 5.0313 0.9985 3124605 ChemDiv3_016316 CSc1ncc(C(=O)NC2CCCCC2)c(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F15 compound treatment 0.468 0.217 3.11 0.4 0.185 3.1 4.3863 1.0 3043779 ChemDiv3_016317 Cc1ccc(CNC(=O)Cn2c(SCc3ccccc3F)nc4cccnc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F16 compound treatment 0.493 0.242 3.46 0.421 0.205 3.45 4.8884 1.0 3043780 ChemDiv3_016318 CN(C1CCCCC1)S(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F17 compound treatment 0.432 0.181 2.59 0.413 0.198 3.31 4.1765 0.9926 3043781 ChemDiv3_016319 Clc1ccc2Oc3ncccc3C(=O)N(CC(=O)N4CCc5ccccc45)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F18 compound treatment 0.534 0.283 4.05 0.419 0.203 3.42 5.2794 0.9964 3043782 ChemDiv3_016320 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F19 compound treatment 0.302 0.0512 0.73 0.31 0.0945 1.59 1.6393 0.9384 3043783 ChemDiv3_016321 CCc1cccc(NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F20 compound treatment 0.468 0.217 3.11 0.366 0.15 2.53 3.9828 0.9947 3043784 ChemDiv3_016322 CN(Cc1ccccc1)S(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F21 compound treatment 0.417 0.166 2.38 0.357 0.141 2.37 3.3602 1.0 3124606 ChemDiv3_016323 CN(CC(=O)Nc1cccnc1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F22 compound treatment 0.457 0.206 2.95 0.283 0.0675 1.13 2.8865 0.9136 3043785 ChemDiv3_016324 CCn1c(=O)n(c2ccccc2)c(=O)c3n(C)c4ccc(C)cc4c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F23 mock treatment 0.27 0.0192 0.27 0.247 0.0315 0.53 0.5679 0.9534 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 F24 mock treatment 0.246 -0.00481 -0.07 0.215 -5.0E-4 -0.01 -0.0546 -0.7875 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G01 compound treatment 0.267 0.0162 0.23 0.207 -0.0085 -0.14 0.0628 0.2311 3124607 ChemDiv3_016325 CC1CCCCN1CCNC(=O)C2C(N(C3CCCC3)C(=O)c4ccccc24)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G02 compound treatment 0.286 0.0352 0.5 0.23 0.0145 0.24 0.528 0.9444 3043786 ChemDiv3_016326 CC1CCC(CC1)NC(=O)CCn2c(=O)c3cccn3c4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G03 compound treatment 0.468 0.217 3.11 0.227 0.0115 0.19 2.3332 0.7496 3124608 ChemDiv3_016327 COc1cccc(c1)n2cc(C(=O)Nc3cccnc3)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G04 compound treatment 0.45 0.199 2.85 0.182 -0.0335 -0.56 1.617 0.5568 3043787 ChemDiv3_016328 Cn1cc(CCC(=O)N2CCc3ccccc23)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G05 compound treatment 0.469 0.218 3.12 0.24 0.0245 0.41 2.4976 0.7934 3124609 ChemDiv3_016329 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)N(CC=C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G06 compound treatment 0.278 0.0272 0.39 0.371 0.156 2.61 2.1205 0.8036 3124610 ChemDiv3_016330 Clc1ccccc1Cn2cc(CCC(=O)N3CCc4ccccc34)c5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G07 compound treatment 0.535 0.284 4.06 0.368 0.153 2.56 4.6842 0.9751 3043788 ChemDiv3_016331 CCCNS(=O)(=O)c1cc2OCCN(C)c2cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G08 compound treatment 0.534 0.283 4.05 0.344 0.129 2.16 4.3893 0.9565 3124611 ChemDiv3_016332 Fc1ccc(Cn2cc(CCC(=O)NC3CCCc4ccccc34)c5ccccc25)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G09 compound treatment 0.514 0.263 3.76 0.3 0.0845 1.42 3.6648 0.911 3043789 ChemDiv3_016333 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NCCCN4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G10 compound treatment 0.433 0.182 2.61 0.426 0.21 3.53 4.3409 0.9888 3124612 ChemDiv3_016334 COc1ccc(cc1)c2noc(CC(=O)N(C)c3ccccc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G11 compound treatment 0.537 0.286 4.09 0.459 0.243 4.09 5.7844 1.0 3124613 ChemDiv3_016335 O=C(CCS(=O)(=O)c1ccc2NC(=O)COc2c1)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G12 compound treatment 0.355 0.104 1.49 0.474 0.259 4.34 4.1217 0.8985 3043790 ChemDiv3_016336 COc1ccc(cc1)N2CCN(CC2)C(=O)CCS(=O)(=O)c3ccc4nc(C)sc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G13 compound treatment 0.403 0.152 2.18 0.412 0.197 3.3 3.8713 0.9797 3124614 ChemDiv3_016337 CCCN(CCC)S(=O)(=O)c1c[nH]c(c1)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G14 compound treatment 0.469 0.218 3.12 0.443 0.228 3.82 4.9068 0.995 3043791 ChemDiv3_016338 O=S(=O)(c1nnn2c3ccsc3c(nc12)N4CCCCC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G15 compound treatment 0.457 0.206 2.95 0.417 0.202 3.38 4.4768 0.9977 3124615 ChemDiv3_016339 COC(=O)c1cc(c[nH]1)S(=O)(=O)NCC2CCCO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G16 compound treatment 0.474 0.223 3.19 0.413 0.198 3.31 4.6013 0.9998 3124616 ChemDiv3_016340 Cc1ccc(NC(=O)NCc2noc3ccccc23)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G17 compound treatment 0.342 0.0912 1.3 0.349 0.134 2.24 2.5067 0.9668 3043792 ChemDiv3_016341 COC(=O)c1cc(c[nH]1)S(=O)(=O)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G18 compound treatment 0.459 0.208 2.98 0.386 0.171 2.86 4.1292 0.9998 3124617 ChemDiv3_016342 CN(C1CCCCC1)C(=O)NCc2noc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G19 compound treatment 0.499 0.248 3.55 0.369 0.154 2.58 4.332 0.9876 3043793 ChemDiv3_016343 COc1ccc2c(CNCCc3ccccc3OC)c(C(=O)O)n(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G20 compound treatment 0.437 0.186 2.66 0.327 0.112 1.87 3.2064 0.9851 3124618 ChemDiv3_016344 CC1CN(C(=O)C)c2ccc(cc2O1)S(=O)(=O)N(C)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G21 compound treatment 0.397 0.146 2.09 0.275 0.0595 1.0 2.1847 0.9428 3124619 ChemDiv3_016345 Cc1ccc(Cl)cc1NC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G22 compound treatment 0.376 0.125 1.79 0.188 -0.0275 -0.46 0.9398 0.5082 3043794 ChemDiv3_016346 CC(C)N(Cc1ccccc1)C(=O)CN2C(=O)CSc3cc(ccc23)S(=O)(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G23 mock treatment 0.28 0.0292 0.42 0.19 -0.0255 -0.43 -0.0074 -0.0124 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 G24 mock treatment 0.248 -0.00281 -0.04 0.179 -0.0365 -0.61 -0.4616 -0.7519 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H01 compound treatment 0.219 -0.0318 -0.46 0.208 -0.0075 -0.13 -0.4108 -0.87 3124620 ChemDiv3_016347 CCOc1ccccc1NC(=O)CCc2nnc3ccc(nn23)N4CCN(C)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H02 compound treatment 0.243 -0.00781 -0.11 0.226 0.0105 0.18 0.0456 0.2185 3043795 ChemDiv3_016348 CCCCN(C)C(=O)Nc1cn(C)c(=O)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H03 compound treatment 0.455 0.204 2.92 0.156 -0.0595 -1.0 1.359 0.4403 3124728 ChemDiv3_016349 CCN(C(=O)C1CCCN(C1)c2nc(no2)c3ccc(OC)cc3)c4ccccc4F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H04 compound treatment 0.483 0.232 3.32 0.231 0.0155 0.26 2.5324 0.7602 3043796 ChemDiv3_016350 CCN(c1ccc(CC)cc1)c2ncnc3n4CCCCCc4nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H05 compound treatment 0.472 0.221 3.16 0.317 0.102 1.7 3.4418 0.9578 3124729 ChemDiv3_016351 COc1ccccc1NC(=O)C2CCN(CC2)c3nn4cc(nc4s3)c5ccc(C)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H06 compound treatment 0.33 0.0792 1.13 0.315 0.0995 1.67 1.9818 0.9821 3124730 ChemDiv3_016352 CCOc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H07 compound treatment 0.395 0.144 2.06 0.422 0.206 3.47 3.9091 0.9693 3043797 ChemDiv3_016353 CNC(=O)Cn1c(cc2ccccc12)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H08 compound treatment 0.464 0.213 3.05 0.318 0.102 1.72 3.3727 0.9633 3124731 ChemDiv3_016354 Cc1cc(C)n(n1)c2nc3cc(Cl)ccc3nc2NCCN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H09 compound treatment 0.567 0.316 4.52 0.398 0.183 3.06 5.3639 0.982 3043798 ChemDiv3_016355 COC(=O)c1ccccc1NC(=O)N2CCC(CN3CCOCC3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H10 compound treatment 0.399 0.148 2.12 0.332 0.117 1.96 2.8814 0.9992 3124732 ChemDiv3_016356 Clc1ccc(cc1)c2nc(C(=O)N3CCc4ccccc34)c5CCCCCn25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H11 compound treatment 0.463 0.212 3.04 0.407 0.192 3.21 4.4189 0.9996 3124733 ChemDiv3_016357 O=C(Nc1ccc2OCCOc2c1)N3CCC(CN4CCc5ccccc5C4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H12 compound treatment 0.456 0.205 2.93 0.438 0.223 3.73 4.716 0.9929 3043799 ChemDiv3_016358 COc1ccc(cc1OC)c2noc(CSCC(=O)Nc3ccc(cc3)C(C)C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H13 compound treatment 0.576 0.325 4.65 0.414 0.199 3.33 5.6448 0.9866 3124734 ChemDiv3_016359 CN(C(=O)CSc1nc2cccnc2[nH]1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H14 compound treatment 0.543 0.292 4.18 0.411 0.196 3.28 5.2755 0.9928 3043800 ChemDiv3_016360 CSc1ncc(C(=O)N2CCCc3ccccc23)c(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H15 compound treatment 0.504 0.253 3.62 0.369 0.154 2.58 4.3825 0.9861 3124735 ChemDiv3_016361 CC1CCc2c(C1)cc(C)n2c3ccc(cc3)C(=O)NCC4CCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H16 compound treatment 0.549 0.298 4.27 0.395 0.179 3.01 5.1463 0.9855 3043801 ChemDiv3_016362 CSc1cccc(NS(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H17 compound treatment 0.387 0.136 1.95 0.489 0.274 4.59 4.6234 0.9271 3124736 ChemDiv3_016363 CCc1cccc(NS(=O)(=O)c2ccc3N(C(C)Cc3c2)C(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H18 compound treatment 0.368 0.117 1.68 0.429 0.214 3.58 3.7191 0.9401 3124737 ChemDiv3_016364 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H19 compound treatment 0.401 0.15 2.15 0.415 0.2 3.35 3.8867 0.977 3043802 ChemDiv3_016365 CC1CCCC(NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H20 compound treatment 0.494 0.243 3.48 0.359 0.143 2.41 4.1627 0.9839 3124738 ChemDiv3_016366 O=C1N(Cc2ccc(cc2)S(=O)(=O)NC3CCCC3)C(=O)c4ncccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H21 compound treatment 0.412 0.161 2.31 0.379 0.164 2.74 3.5707 0.9962 3124739 ChemDiv3_016367 CN(Cc1ccccc1)C(=O)CN(C)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H22 compound treatment 0.467 0.216 3.09 0.29 0.0745 1.25 3.0707 0.9206 3043803 ChemDiv3_016368 CCc1ccccc1NCc2c(O)c(C)ncc2CO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H23 mock treatment 0.362 0.111 1.59 0.222 0.0065 0.11 1.2017 0.7538 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 H24 mock treatment 0.183 -0.0678 -0.97 0.201 -0.0145 -0.24 -0.858 -0.8579 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I01 compound treatment 0.231 -0.0198 -0.28 0.217 0.0015 0.03 -0.1826 -0.6418 3124740 ChemDiv3_016369 COc1ccc(cc1)n2cc(C(=O)N(Cc3ccco3)C4CCCC4)c5ccccc5c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I02 compound treatment 0.24 -0.0108 -0.15 0.237 0.0215 0.36 0.1458 0.3714 3043804 ChemDiv3_016370 CCN1CCCC1CNC(=O)CCn2c(=O)c3cccn3c4cccnc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I03 compound treatment 0.458 0.207 2.96 0.232 0.0165 0.28 2.2914 0.7698 3124741 ChemDiv3_016371 COc1cccc(c1)n2cc(C(=O)NCc3ccccc3Cl)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I04 compound treatment 0.284 0.0332 0.47 0.237 0.0215 0.36 0.5908 0.9908 3043805 ChemDiv3_016372 Cn1cc(CCC(=O)NCc2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I05 compound treatment 0.34 0.0892 1.28 0.22 0.0045 0.08 0.9555 0.7477 3124742 ChemDiv3_016373 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)N3CCc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I06 compound treatment 0.534 0.283 4.05 0.402 0.187 3.13 5.0776 0.9919 3043806 ChemDiv3_016374 CNC(=O)CCc1cn(Cc2ccccc2Cl)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I07 compound treatment 0.445 0.194 2.78 0.275 0.0595 1.0 2.6702 0.9046 3124743 ChemDiv3_016375 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I08 compound treatment 0.408 0.157 2.25 0.442 0.227 3.8 4.278 0.9686 3124744 ChemDiv3_016376 CC(CCc1ccccc1)NC(=O)CCc2cn(Cc3ccc(F)cc3)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I09 compound treatment 0.304 0.0532 0.76 0.417 0.202 3.38 2.9294 0.8451 3043807 ChemDiv3_016377 Cc1ccc(cc1)c2nc(C(=O)N3CCN(Cc4ccccc4)CC3)c5CCCCCn25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I10 compound treatment 0.426 0.175 2.51 0.368 0.153 2.56 3.5818 0.9999 3124745 ChemDiv3_016378 COc1ccc(cc1)c2noc(CC(=O)N(C(C)C)C3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I11 compound treatment 0.234 -0.0168 -0.24 0.437 0.222 3.72 2.4587 0.66 3124746 ChemDiv3_016379 COc1ccccc1N(C)C(=O)CCS(=O)(=O)c2ccc3NC(=O)COc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I12 compound treatment 0.483 0.232 3.32 0.358 0.142 2.39 4.0396 0.987 3043808 ChemDiv3_016380 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c3ccc4N(C)C(=O)C(C)(C)c4c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I13 compound treatment 0.516 0.265 3.79 0.346 0.131 2.19 4.231 0.9659 3124747 ChemDiv3_016381 CCc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I14 compound treatment 0.537 0.286 4.09 0.351 0.136 2.27 4.5027 0.9615 3043809 ChemDiv3_016382 O=S(=O)(c1nnn2c3ccsc3c(Nc4ccccc4)nc12)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I15 compound treatment 0.547 0.296 4.24 0.435 0.22 3.68 5.6008 0.9976 3124748 ChemDiv3_016383 COC(=O)c1cc(c[nH]1)S(=O)(=O)NC2CCCCC2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I16 compound treatment 0.519 0.268 3.84 0.435 0.22 3.68 5.3176 0.9998 3124749 ChemDiv3_016384 O=C(NCc1noc2ccccc12)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I17 compound treatment 0.407 0.156 2.23 0.399 0.184 3.08 3.7575 0.9876 3043810 ChemDiv3_016385 O=C(CCNS(=O)(=O)c1ccc2[nH]c(nc2c1)c3ccccc3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I18 compound treatment 0.331 0.0802 1.15 0.448 0.233 3.9 3.5704 0.8778 3124750 ChemDiv3_016386 CC1CCCC(NC(=O)NCc2noc3ccc(C)cc23)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I19 compound treatment 0.433 0.182 2.61 0.332 0.117 1.96 3.2253 0.99 3124751 ChemDiv3_016387 COc1ccc2c(CNCCc3ccccc3Cl)c([nH]c2c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I20 compound treatment 0.455 0.204 2.92 0.259 0.0435 0.73 2.5815 0.8575 3043811 ChemDiv3_016388 CSc1cccc(NS(=O)(=O)c2ccc3N(CC(C)Oc3c2)C(=O)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I21 compound treatment 0.409 0.158 2.26 0.26 0.0445 0.75 2.1281 0.8931 3124752 ChemDiv3_016389 Clc1ccc(CCNC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I22 compound treatment 0.453 0.202 2.89 0.214 -0.0015 -0.03 2.0272 0.7009 3043812 ChemDiv3_016390 O=C(CN1C(=O)CSc2cc(ccc12)S(=O)(=O)N3CCCC3)NCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I23 mock treatment 0.3 0.0492 0.7 0.216 5.0E-4 0.01 0.5034 0.7155 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 I24 mock treatment 0.244 -0.00681 -0.1 0.21 -0.0055 -0.09 -0.1342 -0.9996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J01 compound treatment 0.289 0.0382 0.55 0.232 0.0165 0.28 0.5821 0.9504 3124753 ChemDiv3_016391 CCn1c(=O)c2sccc2n3c(CCCC(=O)Nc4ccccc4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J02 compound treatment 0.284 0.0332 0.47 0.252 0.0365 0.61 0.7689 0.9921 3043962 ChemDiv3_016392 CCN(C(=O)Nc1cn(C)c(=O)c2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J03 compound treatment 0.394 0.143 2.05 0.235 0.0195 0.33 1.6797 0.8098 3043963 ChemDiv3_016393 COc1ccc(cc1)c2noc(n2)N3CCCC(C3)C(=O)Nc4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J04 compound treatment 0.267 0.0162 0.23 0.192 -0.0235 -0.39 -0.1152 -0.2518 3043965 ChemDiv3_016394 COc1ccc(Nc2cc(C)c3cc(NC(=O)c4ccc(OC)cc4)ccc3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J05 compound treatment 0.291 0.0402 0.57 0.299 0.0835 1.4 1.3975 0.9225 3044021 ChemDiv3_016395 Cc1ccc(cc1)c2cn3nc(sc3n2)N4CCC(CC4)C(=O)NCCCN5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J06 compound treatment 0.508 0.257 3.68 0.392 0.176 2.96 4.696 0.9942 3044022 ChemDiv3_016396 CC(CC(=O)N(C)Cc1ccccc1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J07 compound treatment 0.462 0.211 3.02 0.249 0.0335 0.56 2.5336 0.8246 3044024 ChemDiv3_016397 CC1Cn2cc(C(=O)NCc3ccccc3)c(=O)c4c(Cl)ccc(O1)c24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J08 compound treatment 0.422 0.171 2.45 0.28 0.0645 1.08 2.4969 0.9326 3044025 ChemDiv3_016398 COc1ccc(cc1OC)C2C3=C(CCCC3=O)Nc4[nH]nc(c24)c5ccc(Cl)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J09 compound treatment 0.303 0.0522 0.75 0.422 0.206 3.47 2.9786 0.8401 3044027 ChemDiv3_016399 Cc1ccc(Cl)cc1NC(=O)N2CCC(CN3CCOCC3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J10 compound treatment 0.362 0.111 1.59 0.389 0.173 2.91 3.1837 0.9595 3044028 ChemDiv3_016400 COc1ccc(cc1OC)c2noc(NCCCN3CCCC3=O)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J11 compound treatment 0.3 0.0492 0.7 0.402 0.187 3.13 2.7109 0.845 3124754 ChemDiv3_016401 CCOc1ccc(NC(=O)N2CCCC(CN3CCc4ccccc4C3)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J12 compound treatment 0.516 0.265 3.79 0.456 0.24 4.04 5.5364 0.9995 3044030 ChemDiv3_016402 CCCCN(C)C(=O)Cn1ncc2c3ccccc3n(CCC)c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J13 compound treatment 0.488 0.237 3.39 0.419 0.203 3.42 4.8141 1.0 3124866 ChemDiv3_016403 CCC(Sc1nc2cccnc2[nH]1)C(=O)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J14 compound treatment 0.531 0.28 4.01 0.28 0.0645 1.08 3.5994 0.867 3124867 ChemDiv3_016404 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J15 compound treatment 0.428 0.177 2.53 0.424 0.208 3.5 4.2666 0.9875 3044032 ChemDiv3_016405 CC1CCc2c(C1)cc(C)n2c3ccc(cc3)C(=O)N4CCC5(CC4)OCCO5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J16 compound treatment 0.357 0.106 1.52 0.471 0.256 4.29 4.1063 0.9026 3124868 ChemDiv3_016406 CCC(C)(C)NS(=O)(=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J17 compound treatment 0.336 0.0852 1.22 0.388 0.172 2.9 2.9089 0.926 3044034 ChemDiv3_016407 CCC(C)NS(=O)(=O)c1ccc2[nH]c3CCCCc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J18 compound treatment 0.444 0.193 2.76 0.424 0.208 3.5 4.4284 0.9932 3124869 ChemDiv3_016408 Cc1cccc(NS(=O)(=O)c2ccc(CCN3C(=O)c4cccnc4C3=O)cc2)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J19 compound treatment 0.457 0.206 2.95 0.283 0.0675 1.13 2.8865 0.9136 3124870 ChemDiv3_016409 CN(c1cccc(C)c1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J20 compound treatment 0.451 0.2 2.86 0.273 0.0575 0.97 2.7072 0.8959 3044036 ChemDiv3_016410 CCc1ccc(NS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J21 compound treatment 0.44 0.189 2.71 0.265 0.0495 0.83 2.501 0.8835 3124871 ChemDiv3_016411 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3ccc4[nH]c5CCCCc5c4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J22 compound treatment 0.422 0.171 2.45 0.245 0.0295 0.5 2.0815 0.8332 3044037 ChemDiv3_016412 Fc1ccc(F)c(NS(=O)(=O)c2ccc(cc2)n3cccn3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J23 mock treatment 0.313 0.0622 0.89 0.218 0.0025 0.04 0.6586 0.7396 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 J24 mock treatment 0.234 -0.0168 -0.24 0.202 -0.0135 -0.23 -0.3303 -0.9996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K01 compound treatment 0.227 -0.0238 -0.34 0.245 0.0295 0.5 0.1093 0.1818 3124872 ChemDiv3_016413 COc1cccc(c1)n2cc(C(=O)N3CCCCCC3)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K02 compound treatment 0.286 0.0352 0.5 0.206 -0.0095 -0.16 0.2431 0.4605 3124873 ChemDiv3_016414 Cc1cccc(N2CCN(CCNC(=O)CCn3c(=O)c4cccn4c5cccnc35)CC2)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K03 compound treatment 0.443 0.192 2.75 0.233 0.0175 0.29 2.1515 0.7782 3044040 ChemDiv3_016415 COc1cccc(c1)n2cc(C(=O)N3C(C)CCCC3C)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K04 compound treatment 0.365 0.114 1.63 0.288 0.0725 1.22 2.0154 0.9895 3124874 ChemDiv3_016416 Cn1cc(CCC(=O)NCCCc2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K05 compound treatment 0.297 0.0462 0.66 0.259 0.0435 0.73 0.9834 0.9988 3044043 ChemDiv3_016417 CCN(c1cccc(C)c1)S(=O)(=O)c2ccc3NC(=O)C(C)Sc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K06 compound treatment 0.547 0.296 4.24 0.362 0.146 2.46 4.7344 0.9665 3124875 ChemDiv3_016418 Cc1ccc(Cn2cc(CCC(=O)N3CCc4ccccc34)c5ccccc25)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K07 compound treatment 0.444 0.193 2.76 0.23 0.0145 0.24 2.126 0.7664 3044045 ChemDiv3_016419 CC1CCN(CC1)C(=O)c2noc-3c2COc4ccc(C)cc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K08 compound treatment 0.536 0.285 4.08 0.411 0.196 3.28 5.2047 0.9942 3044084 ChemDiv3_016420 COc1ccc(cc1)c2noc(CC(=O)Nc3cccc(OC)c3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K09 compound treatment 0.421 0.17 2.43 0.372 0.157 2.63 3.5787 0.9993 3044085 ChemDiv3_016421 CCCCN(C)C(=O)c1nc(c2ccc(C)cc2)n3CCCCCc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K10 compound treatment 0.509 0.258 3.69 0.414 0.199 3.33 4.9672 0.9987 3044087 ChemDiv3_016422 COc1ccc(cc1)c2noc(CC(=O)NCCCN3C(C)CCCC3C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K11 compound treatment 0.371 0.12 1.72 0.413 0.198 3.31 3.5596 0.9533 3044089 ChemDiv3_016423 CC1CCN(CC1)C(=O)CCS(=O)(=O)c2ccc3NC(=O)CSc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K12 compound treatment 0.499 0.248 3.55 0.38 0.165 2.76 4.4625 0.9923 3044091 ChemDiv3_016424 CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)N3CCCC3C(=O)NCc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K13 compound treatment 0.519 0.268 3.84 0.387 0.172 2.88 4.7479 0.99 3044092 ChemDiv3_016425 CCc1ccc(NC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K14 compound treatment 0.537 0.286 4.09 0.27 0.0545 0.91 3.5414 0.8443 3124876 ChemDiv3_016426 O=C(NCc1noc2ccccc12)Nc3ccc4OCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K15 compound treatment 0.491 0.24 3.44 0.376 0.161 2.69 4.3341 0.9928 3124877 ChemDiv3_016427 CC1CCCC(NC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCCC3)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K16 compound treatment 0.447 0.196 2.81 0.372 0.157 2.63 3.8416 0.9995 3044095 ChemDiv3_016428 O=C(NCc1noc2ccccc12)Nc3nccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K17 compound treatment 0.388 0.137 1.96 0.374 0.159 2.66 3.2686 0.9888 3124878 ChemDiv3_016429 O=C(C1CCCN1S(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4)N5CCOCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K18 compound treatment 0.427 0.176 2.52 0.38 0.165 2.76 3.7343 0.999 3044096 ChemDiv3_016430 CCOC(=O)c1ccccc1NC(=O)NCc2noc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K19 compound treatment 0.479 0.228 3.26 0.371 0.156 2.61 4.1534 0.9939 3124879 ChemDiv3_016431 Cc1ccc2c(CNC3CCCC3)c(C(=O)O)n(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K20 compound treatment 0.285 0.0342 0.49 0.274 0.0585 0.98 1.0401 0.9482 3124880 ChemDiv3_016432 CC(=O)N1CCOc2cc(ccc12)S(=O)(=O)NCC3CCC(CC3)C(=O)Nc4cccc(C)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K21 compound treatment 0.38 0.129 1.85 0.202 -0.0135 -0.23 1.1464 0.6158 3044099 ChemDiv3_016433 O=C(CCN1C(=O)c2ccccc2Sc3ncccc13)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K22 compound treatment 0.376 0.125 1.79 0.211 -0.0045 -0.08 1.2128 0.6767 3124881 ChemDiv3_016434 CCC1Sc2cc(ccc2NC1=O)S(=O)(=O)Nc3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K23 mock treatment 0.229 -0.0218 -0.31 0.234 0.0185 0.31 -0.0011 -0.0024 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 K24 mock treatment 0.201 -0.0498 -0.71 0.198 -0.0175 -0.29 -0.7115 -0.9232 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L01 compound treatment 0.244 -0.00681 -0.1 0.231 0.0155 0.26 0.1151 0.4142 3044102 ChemDiv3_016435 CCn1c(=O)c2sccc2n3c(CCCC(=O)NCc4cccnc4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L02 compound treatment 0.26 0.00919 0.13 0.229 0.0135 0.23 0.2531 0.9664 3124882 ChemDiv3_016436 CCN(Cc1ccccc1)C(=O)Nc2cn(C)c(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L03 compound treatment 0.467 0.216 3.09 0.219 0.0035 0.06 2.2281 0.7204 3044104 ChemDiv3_016437 Fc1cccc(c1)c2nc(C(=O)Nc3ccc(F)cc3F)c4CCCCCn24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L04 compound treatment 0.304 0.0532 0.76 0.181 -0.0345 -0.58 0.1285 0.1344 3124883 ChemDiv3_016438 Cc1cc(Nc2cccc(Cl)c2)nc3ccc(NC(=O)c4ccc(=O)[nH]c4)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L05 compound treatment 0.251 1.88E-4 0.0 0.218 0.0025 0.04 0.0316 0.7508 3124884 ChemDiv3_016439 CCCCN(C)C(=O)C1CCN(CC1)c2nn3cc(nc3s2)c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L06 compound treatment 0.434 0.183 2.62 0.3 0.0845 1.42 2.8557 0.9584 3044106 ChemDiv3_016440 CC(CC(=O)Nc1ccc(C)cc1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L07 compound treatment 0.407 0.156 2.23 0.338 0.123 2.06 3.0336 0.9991 3124885 ChemDiv3_016441 CC(C)NC(=O)c1cn2CC(C)Oc3ccc(Cl)c(c1=O)c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L08 compound treatment 0.352 0.101 1.45 0.364 0.148 2.49 2.7858 0.9666 3124886 ChemDiv3_016442 Clc1ccc(cc1)c2nc(C(=O)NCc3cccnc3)c4CCCCCn24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L09 compound treatment 0.417 0.166 2.38 0.23 0.0145 0.24 1.8529 0.7754 3044108 ChemDiv3_016443 CCOc1ccc(NC(=O)N2CCC(CN3CCOCC3)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L10 compound treatment 0.568 0.317 4.54 0.33 0.115 1.92 4.567 0.9269 3044144 ChemDiv3_016444 CCOc1ccc(CCNc2nc(no2)c3ccc(OC)c(OC)c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L11 compound treatment 0.334 0.0832 1.19 0.299 0.0835 1.4 1.8324 0.9967 3044145 ChemDiv3_016445 Brc1cccc(NC(=O)N2CCCC(CN3CCc4ccccc4C3)C2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L12 compound treatment 0.512 0.261 3.74 0.32 0.105 1.75 3.8819 0.9406 3044147 ChemDiv3_016446 O=C(Cn1ncc2c3ccccc3[nH]c2c1=O)NCCC4=CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L13 compound treatment 0.395 0.144 2.06 0.37 0.155 2.59 3.292 0.9936 3044148 ChemDiv3_016447 CCC(Sc1nc2cccnc2[nH]1)C(=O)NC3CCC(C)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L14 compound treatment 0.535 0.284 4.06 0.237 0.0215 0.36 3.1295 0.7669 3044149 ChemDiv3_016448 CCCN(CCC)S(=O)(=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L15 compound treatment 0.463 0.212 3.04 0.364 0.148 2.49 3.9085 0.9952 3044151 ChemDiv3_016449 Cc1cc2CCCCCc2n1c3ccc(cc3)C(=O)N4CCN(CC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L16 compound treatment 0.491 0.24 3.44 0.431 0.216 3.62 4.9869 0.9997 3124887 ChemDiv3_016450 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L17 compound treatment 0.5 0.249 3.56 0.323 0.108 1.8 3.7962 0.9502 3124888 ChemDiv3_016451 COc1ccc(CCNS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L18 compound treatment 0.488 0.237 3.39 0.415 0.2 3.35 4.7667 1.0 3044153 ChemDiv3_016452 CCN(c1ccccc1)S(=O)(=O)c2ccc(CCN3C(=O)c4cccnc4C3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L19 compound treatment 0.482 0.231 3.31 0.321 0.106 1.77 3.5904 0.9572 3124889 ChemDiv3_016453 CCN(CC)S(=O)(=O)c1ccc2[nH]c3CCCCc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L20 compound treatment 0.272 0.0212 0.3 0.306 0.0905 1.52 1.2884 0.8318 3044155 ChemDiv3_016454 O=C1N(Cc2ccc(cc2)S(=O)(=O)N3CCc4ccccc34)C(=O)c5ncccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L21 compound treatment 0.31 0.0592 0.85 0.284 0.0685 1.15 1.4116 0.9887 3124890 ChemDiv3_016455 CN(CC(=O)N1CCCC1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L22 compound treatment 0.298 0.0472 0.67 0.291 0.0755 1.27 1.3733 0.9565 3044156 ChemDiv3_016456 CCc1ccccc1NS(=O)(=O)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L23 mock treatment 0.253 0.00219 0.03 0.231 0.0155 0.26 0.2061 0.7865 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 L24 mock treatment 0.225 -0.0258 -0.37 0.224 0.0085 0.14 -0.1602 -0.4047 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M01 compound treatment 0.296 0.0452 0.65 0.259 0.0435 0.73 0.9733 0.9982 3124891 ChemDiv3_016457 COc1cccc(c1)n2cc(C(=O)NC(C)C)c3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M02 compound treatment 0.282 0.0312 0.45 0.253 0.0375 0.63 0.7605 0.9858 3124892 ChemDiv3_016458 CC1=C(SCCO1)C(=O)Nc2ccc(Cl)cc2C(=O)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M03 compound treatment 0.43 0.179 2.56 0.235 0.0195 0.33 2.0438 0.791 3044159 ChemDiv3_016459 COc1cccc(c1)n2cc(C(=O)N3CCC(=CC3)c4ccccc4)c5ccccc5c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M04 compound treatment 0.378 0.127 1.82 0.239 0.0235 0.39 1.5653 0.8409 3125001 ChemDiv3_016460 CCn1cc(CCC(=O)NCc2ccco2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M05 compound treatment 0.353 0.102 1.46 0.228 0.0125 0.21 1.1819 0.8004 3125002 ChemDiv3_016461 CC1Sc2cc(ccc2NC1=O)S(=O)(=O)N3CCC(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M06 compound treatment 0.378 0.127 1.82 0.255 0.0395 0.66 1.7552 0.9065 3044161 ChemDiv3_016462 CC(C)NC(=O)CCc1cn(Cc2ccc(C)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M07 compound treatment 0.476 0.225 3.22 0.28 0.0645 1.08 3.0431 0.8955 3125003 ChemDiv3_016463 CCN1CCCC1CNC(=O)c2noc-3c2COc4ccc(C)cc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M08 compound treatment 0.277 0.0262 0.37 0.275 0.0595 1.0 0.971 0.9104 3044162 ChemDiv3_016464 COc1ccc(cc1)c2noc(CC(=O)N(C)Cc3ccccc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M09 compound treatment 0.438 0.187 2.68 0.216 5.0E-4 0.01 1.8992 0.7093 3125004 ChemDiv3_016465 Cc1ccc(cc1)c2nc(C(=O)NCCN3CCc4ccccc4C3)c5CCCCCn25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M10 compound treatment 0.501 0.25 3.58 0.286 0.0705 1.18 3.3672 0.8933 3044164 ChemDiv3_016466 CC1CN(C(=O)C)c2ccc(cc2O1)S(=O)(=O)N(CC=C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M11 compound treatment 0.32 0.0692 0.99 0.333 0.117 1.97 2.0943 0.9491 3125005 ChemDiv3_016467 CCc1cccc(NC(=O)CCS(=O)(=O)c2ccc3NC(=O)CSc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M12 compound treatment 0.34 0.0892 1.28 0.316 0.101 1.69 2.0948 0.9905 3125006 ChemDiv3_016468 COC(=O)c1ccccc1NS(=O)(=O)c2c(C)nc3sccn3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M13 compound treatment 0.404 0.153 2.19 0.26 0.0445 0.75 2.0775 0.8974 3044167 ChemDiv3_016469 COc1ccc(CNC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M14 compound treatment 0.514 0.263 3.76 0.286 0.0705 1.18 3.4986 0.8866 3125007 ChemDiv3_016470 CC1CC(C)CN(C1)C(=O)NCc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M15 compound treatment 0.434 0.183 2.62 0.318 0.102 1.72 3.0693 0.9792 3044203 ChemDiv3_016471 COC(=O)c1cc(c[nH]1)S(=O)(=O)N2C(C)Cc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M16 compound treatment 0.378 0.127 1.82 0.317 0.102 1.7 2.491 0.9995 3044204 ChemDiv3_016472 CC1CCCC(C)N1CCCNC(=O)NCc2noc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M17 compound treatment 0.441 0.19 2.72 0.332 0.117 1.96 3.3062 0.9869 3044206 ChemDiv3_016473 Cc1ccsc1CCNC(=O)c2cc(c[nH]2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M18 compound treatment 0.482 0.231 3.31 0.312 0.0965 1.62 3.4836 0.9461 3044208 ChemDiv3_016474 COc1cc(Cl)c(C)cc1NC(=O)NCc2noc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M19 compound treatment 0.439 0.188 2.69 0.248 0.0325 0.55 2.2891 0.8335 3044209 ChemDiv3_016475 CSc1ccc(CCNCc2c(C(=O)O)n(C)c3cc(C)ccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M20 compound treatment 0.221 -0.0298 -0.43 0.189 -0.0265 -0.44 -0.616 -0.9998 3044210 ChemDiv3_016476 CCC1Sc2cc(ccc2NC1=O)S(=O)(=O)CCC(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M21 compound treatment 0.232 -0.0188 -0.27 0.229 0.0135 0.23 -0.0301 -0.0854 3125008 ChemDiv3_016477 Cc1ccc(NC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M22 compound treatment 0.218 -0.0328 -0.47 0.208 -0.0075 -0.13 -0.4209 -0.8661 3125009 ChemDiv3_016478 CCC1Sc2cc(ccc2NC1=O)S(=O)(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M23 mock treatment 0.262 0.0112 0.16 0.207 -0.0085 -0.14 0.0123 0.0573 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 M24 mock treatment 0.224 -0.0268 -0.38 0.25 0.0345 0.58 0.1383 0.1991 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N01 compound treatment 0.274 0.0232 0.33 0.209 -0.0065 -0.11 0.1574 0.4508 3044213 ChemDiv3_016479 CCn1c(=O)c2sccc2n3c(CCCC(=O)NCCc4ccccc4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N02 compound treatment 0.279 0.0282 0.4 0.22 0.0045 0.08 0.3385 0.8252 3125010 ChemDiv3_016480 Cn1cc(NC(=O)N(CC2CCCO2)Cc3ccco3)c4ccccc4c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N03 compound treatment 0.338 0.0872 1.25 0.233 0.0175 0.29 1.0895 0.8504 3044215 ChemDiv3_016481 CC(C)NC(=O)c1nc(c2cccc(F)c2)n3CCCCCc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N04 compound treatment 0.431 0.18 2.58 0.231 0.0155 0.26 2.0064 0.7745 3125011 ChemDiv3_016482 Fc1ccccc1C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N05 compound treatment 0.499 0.248 3.55 0.267 0.0515 0.86 3.1214 0.8543 3125012 ChemDiv3_016483 CCN1CCN(CC1)C(=O)C2CCCN(C2)c3nn4cc(nc4s3)c5ccc(OC)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N06 compound treatment 0.395 0.144 2.06 0.23 0.0145 0.24 1.6304 0.7851 3044217 ChemDiv3_016484 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N07 compound treatment 0.397 0.146 2.09 0.214 -0.0015 -0.03 1.4608 0.6985 3125013 ChemDiv3_016485 CCOc1ccc(CCNC(=O)c2cn3CC(C)Oc4ccc(Cl)c(c2=O)c43)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N08 compound treatment 0.318 0.0672 0.96 0.257 0.0415 0.7 1.1721 0.9875 3044219 ChemDiv3_016486 Clc1ccc(cc1)c2nc(C(=O)NC3CCCC3)c4CCCCCn24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N09 compound treatment 0.386 0.135 1.93 0.244 0.0285 0.48 1.7056 0.8562 3125014 ChemDiv3_016487 CCOC(=O)c1ccccc1NC(=O)N2CCC(CN3CCCC3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N10 compound treatment 0.5 0.249 3.56 0.231 0.0155 0.26 2.7043 0.7567 3044221 ChemDiv3_016488 COc1ccc(cc1OC)c2noc(n2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N11 compound treatment 0.501 0.25 3.58 0.22 0.0045 0.08 2.5839 0.7219 3125015 ChemDiv3_016489 CCC(NC(=O)Nc1cc(C)cc(C)c1)c2c(sc3CN(CC)CCc23)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N12 compound treatment 0.455 0.204 2.92 0.223 0.0075 0.13 2.1542 0.7369 3044223 ChemDiv3_016490 Fc1ccc(NC(=O)Cn2ncc3c4ccccc4[nH]c3c2=O)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N13 compound treatment 0.372 0.121 1.73 0.279 0.0635 1.07 1.9793 0.9727 3125016 ChemDiv3_016491 CCC(Sc1nc2cccnc2[nH]1)C(=O)N(CC)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N14 compound treatment 0.347 0.0962 1.38 0.284 0.0685 1.15 1.7858 0.996 3125017 ChemDiv3_016492 CC1CCN(CC1)S(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N15 compound treatment 0.41 0.159 2.28 0.256 0.0405 0.68 2.0907 0.8798 3044260 ChemDiv3_016493 Cc1ccc2Oc3ncccc3C(=O)N(CC(=O)NCCc4ccccc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N16 compound treatment 0.517 0.266 3.81 0.23 0.0145 0.24 2.8644 0.7508 3044262 ChemDiv3_016494 Cc1cc2n(C)c(=O)c(=O)n(C)c2cc1S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N17 compound treatment 0.322 0.0712 1.02 0.177 -0.0385 -0.65 0.2631 0.2182 3044264 ChemDiv3_016495 CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N18 compound treatment 0.4 0.149 2.13 0.285 0.0695 1.17 2.3337 0.9596 3044266 ChemDiv3_016496 O=C1N(CCc2ccc(cc2)S(=O)(=O)N3CCCC3)C(=O)c4ncccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N19 compound treatment 0.504 0.253 3.62 0.206 -0.0095 -0.16 2.448 0.6753 3044267 ChemDiv3_016497 O=S(=O)(N1CCCCC1)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N20 compound treatment 0.398 0.147 2.11 0.228 0.0125 0.21 1.637 0.7737 3044269 ChemDiv3_016498 CC1CCCCN1S(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N21 compound treatment 0.43 0.179 2.56 0.282 0.0665 1.12 2.6016 0.9306 3044270 ChemDiv3_016499 CCN(CCCNc1nc(no1)c2cc(OC)ccc2OC)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N22 compound treatment 0.379 0.128 1.83 0.238 0.0225 0.38 1.5635 0.8352 3125018 ChemDiv3_016500 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)n3cccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N23 mock treatment 0.276 0.0252 0.36 0.207 -0.0085 -0.14 0.1539 0.3971 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 N24 mock treatment 0.263 0.0122 0.17 0.218 0.0025 0.04 0.1529 0.8529 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O01 compound treatment 0.293 0.0422 0.6 0.247 0.0315 0.53 0.8005 0.9978 3044273 ChemDiv3_016501 COc1cccc(c1)n2cc(C(=O)NCCC(C)C)c3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O02 compound treatment 0.276 0.0252 0.36 0.21 -0.0055 -0.09 0.1895 0.5095 3125019 ChemDiv3_016502 O=C(CCC(=O)N1CCSc2ccccc12)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O03 compound treatment 0.255 0.00419 0.06 0.225 0.0095 0.16 0.1551 0.9106 3125020 ChemDiv3_016503 COc1cccc(c1)n2cc(C(=O)N(Cc3ccccc3)C(C)C)c4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O04 compound treatment 0.256 0.00519 0.07 0.231 0.0155 0.26 0.2364 0.8739 3044276 ChemDiv3_016504 CCn1cc(CCC(=O)NC(C)c2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O05 compound treatment 0.168 -0.0828 -1.18 0.13 -0.0855 -1.44 -1.8523 -0.9955 3125021 ChemDiv3_016505 CCOc1ccccc1N(C)S(=O)(=O)c2ccc3NC(=O)C(C)Sc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O06 compound treatment 0.327 0.0762 1.09 0.256 0.0405 0.68 1.2512 0.9742 3044278 ChemDiv3_016506 CNC(=O)CCc1cn(Cc2ccc(C)cc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O07 compound treatment 0.265 0.0142 0.2 0.23 0.0145 0.24 0.3156 0.9959 3125022 ChemDiv3_016507 Cc1ccc2OCc3c(noc3-c2c1)C(=O)NC4CCCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O08 compound treatment 0.29 0.0392 0.56 0.237 0.0215 0.36 0.6515 0.9773 3125023 ChemDiv3_016508 COc1ccc(cc1)c2noc(CC(=O)N3CCCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O09 compound treatment 0.246 -0.00481 -0.07 0.236 0.0205 0.34 0.1946 0.5546 3044281 ChemDiv3_016509 Cc1ccc(cc1)c2nc(C(=O)Nc3ccc(Cl)cc3)c4CCCCCn24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O10 compound treatment 0.265 0.0142 0.2 0.196 -0.0195 -0.33 -0.0879 -0.2283 3125024 ChemDiv3_016510 CC(C)C(NS(=O)(=O)c1ccc2N(C)C(=O)C(C)(C)c2c1)C(=O)NCc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O11 compound treatment 0.239 -0.0118 -0.17 0.223 0.0075 0.13 -0.0305 -0.1446 3044283 ChemDiv3_016511 O=C(CCS(=O)(=O)c1ccc2NC(=O)CSc2c1)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O12 compound treatment 0.243 -0.00781 -0.11 0.241 0.0255 0.43 0.2236 0.5055 3044335 ChemDiv3_016512 Cc1nc2sccn2c(=O)c1S(=O)(=O)NC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O13 compound treatment 0.24 -0.0108 -0.15 0.226 0.0105 0.18 0.0153 0.0651 3044336 ChemDiv3_016513 O=C(N1CCCC1)c2cc(c[nH]2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O14 compound treatment 0.269 0.0182 0.26 0.206 -0.0095 -0.16 0.0712 0.2334 3044338 ChemDiv3_016514 CCN(CC)C(=O)NCc1noc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O15 compound treatment 0.241 -0.00981 -0.14 0.209 -0.0065 -0.11 -0.1764 -0.9922 3044340 ChemDiv3_016515 CCN(Cc1ccccc1)S(=O)(=O)c2c[nH]c(c2)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O16 compound treatment 0.242 -0.00881 -0.13 0.208 -0.0075 -0.13 -0.1781 -1.0 3044341 ChemDiv3_016516 CC(NC(=O)NCc1noc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O17 compound treatment 0.257 0.00619 0.09 0.22 0.0045 0.08 0.116 0.9969 3044342 ChemDiv3_016517 CCc1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)N3CCOCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O18 compound treatment 0.341 0.0902 1.29 0.244 0.0285 0.48 1.2504 0.9088 3044343 ChemDiv3_016518 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)N(C)CC(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O19 compound treatment 0.271 0.0202 0.29 0.229 0.0135 0.23 0.3644 0.9928 3125025 ChemDiv3_016519 CCn1c(C(=O)O)c(CNCc2cccc(Cl)c2)c3ccc(C)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O20 compound treatment 0.263 0.0122 0.17 0.226 0.0105 0.18 0.2479 1.0 3044345 ChemDiv3_016520 COc1cc(NC(=O)CN2C(=O)COc3cc(ccc23)S(=O)(=O)N4CCOCC4)cc(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O21 compound treatment 0.268 0.0172 0.25 0.226 0.0105 0.18 0.2985 0.9867 3125026 ChemDiv3_016521 COc1ccccc1NC(=O)CCN2C(=O)c3ccccc3Sc4ncccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O22 compound treatment 0.252 0.00119 0.02 0.219 0.0035 0.06 0.0535 0.8757 3125027 ChemDiv3_016522 CN(CC(=O)Nc1nc2ccc(Cl)cc2s1)S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O23 mock treatment 0.229 -0.0218 -0.31 0.216 5.0E-4 0.01 -0.2147 -0.6878 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 O24 mock treatment 0.198 -0.0528 -0.76 0.242 0.0265 0.44 -0.2197 -0.2506 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P01 compound treatment 0.225 -0.0258 -0.37 0.22 0.0045 0.08 -0.2077 -0.551 3044348 ChemDiv3_016523 CC(C)Cn1c(=O)c2sccc2n3c(CCCC(=O)NC4CCCCCC4)nnc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P02 compound treatment 0.308 0.0572 0.82 0.225 0.0095 0.16 0.6912 0.8293 3125137 ChemDiv3_016524 CSc1ccc(CCNC(=O)Nc2cn(C)c(=O)c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P03 compound treatment 0.277 0.0262 0.37 0.251 0.0355 0.6 0.6862 0.975 3044350 ChemDiv3_016525 CN(C(=O)c1nc(c2cccc(F)c2)n3CCCCCc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P04 compound treatment 0.309 0.0582 0.83 0.282 0.0665 1.12 1.3777 0.9896 3125138 ChemDiv3_016526 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P05 compound treatment 0.281 0.0302 0.43 0.216 5.0E-4 0.01 0.3113 0.7207 3125139 ChemDiv3_016527 CNC(=O)C1CCCN(C1)c2nn3cc(nc3s2)c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P06 compound treatment 0.253 0.00219 0.03 0.241 0.0255 0.43 0.3248 0.7568 3044352 ChemDiv3_016528 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P07 compound treatment 0.258 0.00719 0.1 0.223 0.0075 0.13 0.1617 0.9949 3125140 ChemDiv3_016529 COc1ccc(NC(=O)N2CCC(CN3CCCCC3)CC2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P08 compound treatment 0.224 -0.0268 -0.38 0.248 0.0325 0.55 0.1145 0.1718 3044354 ChemDiv3_016530 CCCNC(=O)c1nc(c2ccc(Cl)cc2)n3CCCCCc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P09 compound treatment 0.232 -0.0188 -0.27 0.228 0.0125 0.21 -0.0419 -0.1229 3125141 ChemDiv3_016531 COC(=O)c1ccccc1NC(=O)N2CCC(CN3CCc4ccccc4C3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P10 compound treatment 0.294 0.0432 0.62 0.245 0.0295 0.5 0.7869 0.994 3125142 ChemDiv3_016532 CCc1ccccc1NC(=O)C2CCCN(C2)c3ncnc4n5CCCCCc5nc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P11 compound treatment 0.237 -0.0138 -0.2 0.261 0.0455 0.76 0.4003 0.5075 3044356 ChemDiv3_016533 CCN1CCC(CC1)N(Cc2ccco2)C(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P12 compound treatment 0.236 -0.0148 -0.21 0.233 0.0175 0.29 0.0579 0.1598 3044358 ChemDiv3_016534 CSc1ncc(C(=O)NCc2ccccc2)c(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P13 compound treatment 0.289 0.0382 0.55 0.342 0.127 2.12 1.8876 0.861 3125143 ChemDiv3_016535 Fc1ccc(CSc2nc3cccnc3n2CC(=O)N4CCCc5ccccc45)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P14 compound treatment 0.289 0.0382 0.55 0.247 0.0315 0.53 0.7601 0.9999 3044412 ChemDiv3_016536 Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)N3CCc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P15 compound treatment 0.293 0.0422 0.6 0.257 0.0415 0.7 0.9192 0.9974 3044414 ChemDiv3_016537 CC1CCCC(NC(=O)CN2C(=O)c3cccnc3Oc4ccc(C)cc24)C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P16 compound treatment 0.22 -0.0308 -0.44 0.22 0.0045 0.08 -0.2582 -0.5775 3044416 ChemDiv3_016538 Cc1cc2n(C)c(=O)c(=O)n(C)c2cc1S(=O)(=O)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P17 compound treatment 0.115 -0.136 -1.94 0.153 -0.0625 -1.05 -2.1154 -0.9582 3044417 ChemDiv3_016539 Fc1ccccc1NS(=O)(=O)c2ccc3[nH]c4CCCCc4c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P18 compound treatment 0.304 0.0532 0.76 0.24 0.0245 0.41 0.8287 0.9583 3044419 ChemDiv3_016540 CN(C1CCCCC1)S(=O)(=O)c2ccc(CCN3C(=O)c4cccnc4C3=O)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P19 compound treatment 0.266 0.0152 0.22 0.202 -0.0135 -0.23 -0.0066 -0.0211 3044420 ChemDiv3_016541 O=S(=O)(Nc1ccc(cc1)c2ccno2)c3ccc4[nH]c5CCCCc5c4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P20 compound treatment 0.252 0.00119 0.02 0.249 0.0335 0.56 0.4096 0.7281 3125144 ChemDiv3_016542 O=C1N(Cc2ccc(cc2)S(=O)(=O)NCc3ccccc3)C(=O)c4ncccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P21 compound treatment 0.277 0.0262 0.37 0.223 0.0075 0.13 0.3539 0.8955 3044422 ChemDiv3_016543 COc1ccc(OC)c(c1)c2noc(NCCc3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P22 compound treatment 0.271 0.0202 0.29 0.254 0.0385 0.65 0.6611 0.9341 3125145 ChemDiv3_016544 O=S(=O)(N1CCCC2CCCCC21)c3ccc(cc3)n4cccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P23 mock treatment 0.259 0.00819 0.12 0.233 0.0175 0.29 0.2905 0.9187 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2047 P24 mock treatment 0.24 -0.0108 -0.15 0.222 0.0065 0.11 -0.0322 -0.1702 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A01 compound treatment 0.244 -0.0136 -0.19 0.235 -0.0217 -0.36 -0.3948 -0.9569 3044425 ChemDiv3_016545 Cc1cccc(NS(=O)(=O)c2ccc(cc2)n3cccn3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A02 compound treatment 0.249 -0.00859 -0.12 0.231 -0.0257 -0.43 -0.3917 -0.8738 3125146 ChemDiv3_016546 CCc1cccc(NS(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A03 compound treatment 0.263 0.00541 0.08 0.238 -0.0187 -0.31 -0.167 -0.5171 3125147 ChemDiv3_016547 CC1Cc2cc(ccc2N1C(=O)C3CC3)S(=O)(=O)CCC(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A04 compound treatment 0.235 -0.0226 -0.32 0.209 -0.0477 -0.8 -0.7944 -0.9204 3044427 ChemDiv3_016548 COC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A05 compound treatment 0.203 -0.0546 -0.78 0.244 -0.0127 -0.21 -0.7027 -0.8682 3044429 ChemDiv3_016549 Cc1ccccc1NS(=O)(=O)c2cc(F)ccc2CN3C(=O)c4cccnc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A06 mock treatment 0.244 -0.0136 -0.19 0.223 -0.0337 -0.57 -0.5372 -0.8986 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A07 compound treatment 0.201 -0.0566 -0.81 0.228 -0.0287 -0.48 -0.9128 -0.9692 3044490 ChemDiv3_016550 Brc1ccc(cc1)N2CC(=O)Nc3ccccc3S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A08 mock treatment 0.22 -0.0376 -0.54 0.227 -0.0297 -0.5 -0.7325 -0.9993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A09 compound treatment 0.247 -0.0106 -0.15 0.248 -0.00868 -0.15 -0.2102 -0.9998 3125148 ChemDiv3_016551 Cc1ccc(CNC(=O)CN2C=NS(=O)(=O)c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A10 mock treatment 0.235 -0.0226 -0.32 0.22 -0.0367 -0.62 -0.6638 -0.9547 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A11 compound treatment 0.225 -0.0326 -0.47 0.204 -0.0527 -0.88 -0.9549 -0.9553 3125149 ChemDiv3_016552 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)NCc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A12 mock treatment 0.214 -0.0436 -0.62 0.219 -0.0377 -0.63 -0.8881 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A13 compound treatment 0.225 -0.0326 -0.47 0.215 -0.0417 -0.7 -0.8243 -0.9805 3044432 ChemDiv3_016553 CC1(C)CC(=O)N(CC(=O)NCc2cccs2)c3ccccc3S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A14 mock treatment 0.218 -0.0396 -0.57 0.231 -0.0257 -0.43 -0.7052 -0.9909 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A15 compound treatment 0.24 -0.0176 -0.25 0.249 -0.00768 -0.13 -0.2691 -0.9518 3125150 ChemDiv3_016554 CC(C)CCNC(=O)C1CCC(=O)N1C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A16 mock treatment 0.239 -0.0186 -0.27 0.207 -0.0497 -0.83 -0.7777 -0.8885 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A17 compound treatment 0.203 -0.0546 -0.78 0.199 -0.0577 -0.97 -1.2367 -0.9943 3044434 ChemDiv3_016555 CCC(C)N1C(CCC1=O)C(=O)NCc2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A18 mock treatment 0.194 -0.0636 -0.91 0.209 -0.0477 -0.8 -1.2091 -0.998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A19 compound treatment 0.194 -0.0636 -0.91 0.218 -0.0387 -0.65 -1.1023 -0.9863 3125151 ChemDiv3_016556 O=C(NCCCN1CCCC1)C2CCC(=O)N2C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A20 mock treatment 0.215 -0.0426 -0.61 0.196 -0.0607 -1.02 -1.1509 -0.9698 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A21 compound treatment 0.202 -0.0556 -0.8 0.216 -0.0407 -0.68 -1.0451 -0.9971 3044491 ChemDiv3_016557 Clc1ccccc1CN2C(CCC2=O)C(=O)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A22 mock treatment 0.192 -0.0656 -0.94 0.23 -0.0267 -0.45 -0.9801 -0.9427 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A23 mock treatment 0.205 -0.0526 -0.75 0.232 -0.0247 -0.41 -0.8248 -0.9605 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 A24 mock treatment 0.213 -0.0446 -0.64 0.236 -0.0207 -0.35 -0.6965 -0.9591 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B01 mock treatment 0.443 0.185 2.65 0.459 0.202 3.4 4.2764 0.9925 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B02 mock treatment 0.223 -0.0346 -0.49 0.207 -0.0497 -0.83 -0.9395 -0.9689 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B03 mock treatment 0.233 -0.0246 -0.35 0.237 -0.0197 -0.33 -0.4823 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B04 mock treatment 0.251 -0.00659 -0.09 0.233 -0.0237 -0.4 -0.3477 -0.8512 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B05 mock treatment 0.254 -0.00359 -0.05 0.272 0.0153 0.26 0.1455 0.5549 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B06 mock treatment 0.255 -0.00259 -0.04 0.24 -0.0167 -0.28 -0.2242 -0.7937 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B07 mock treatment 0.265 0.00741 0.11 0.268 0.0113 0.19 0.2093 0.962 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B08 mock treatment 0.263 0.00541 0.08 0.275 0.0183 0.31 0.2721 0.8583 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B09 mock treatment 0.257 -5.89E-4 -0.01 0.245 -0.0117 -0.2 -0.1446 -0.7368 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B10 mock treatment 0.388 0.13 1.87 0.28 0.0233 0.39 1.5957 0.8372 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B11 mock treatment 0.412 0.154 2.21 0.304 0.0473 0.79 2.1233 0.9047 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B12 mock treatment 0.245 -0.0126 -0.18 0.23 -0.0267 -0.45 -0.444 -0.9199 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B13 mock treatment 0.412 0.154 2.21 0.237 -0.0197 -0.33 1.3281 0.5947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B14 mock treatment 0.272 0.0144 0.21 0.23 -0.0267 -0.45 -0.1709 -0.3467 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B15 mock treatment 0.234 -0.0236 -0.34 0.235 -0.0217 -0.36 -0.4959 -0.9993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B16 mock treatment 0.243 -0.0146 -0.21 0.243 -0.0137 -0.23 -0.31 -0.9989 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B17 mock treatment 0.39 0.132 1.89 0.437 0.18 3.03 3.4792 0.9745 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B18 mock treatment 0.422 0.164 2.35 0.425 0.168 2.83 3.6605 0.9958 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B19 mock treatment 0.233 -0.0246 -0.35 0.42 0.163 2.74 1.6896 0.6114 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B20 mock treatment 0.412 0.154 2.21 0.429 0.172 2.89 3.6068 0.9911 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B21 mock treatment 0.257 -5.89E-4 -0.01 0.387 0.13 2.19 1.5407 0.7044 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B22 mock treatment 0.231 -0.0266 -0.38 0.439 0.182 3.06 1.8948 0.6145 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B23 mock treatment 0.253 -0.00459 -0.07 0.246 -0.0107 -0.18 -0.1732 -0.9071 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 B24 mock treatment 0.223 -0.0346 -0.49 0.206 -0.0507 -0.85 -0.9514 -0.9667 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C01 compound treatment 0.187 -0.0706 -1.01 0.204 -0.0527 -0.88 -1.3392 -0.9978 3044493 ChemDiv3_016558 CCc1cccc(NC(=O)CN2C(=O)COc3cc(ccc23)S(=O)(=O)Nc4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C02 compound treatment 0.24 -0.0176 -0.25 0.235 -0.0217 -0.36 -0.4352 -0.9838 3044494 ChemDiv3_016559 CC1CC(C)CN(C1)C(=O)CN(C)S(=O)(=O)c2cc3OCC(=O)Nc3cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C03 compound treatment 0.221 -0.0366 -0.52 0.227 -0.0297 -0.5 -0.7224 -0.9997 3044496 ChemDiv3_016560 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C04 compound treatment 0.26 0.00241 0.03 0.238 -0.0187 -0.31 -0.1973 -0.6256 3044498 ChemDiv3_016561 Cc1nc2ccc(cc2o1)S(=O)(=O)NC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C05 compound treatment 0.212 -0.0456 -0.65 0.227 -0.0297 -0.5 -0.8134 -0.9912 3044499 ChemDiv3_016562 CC(C)(C)NC(=O)c1cc(n[nH]1)c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C06 mock treatment 0.039 -0.219 -3.13 0.246 -0.0107 -0.18 -2.3376 -0.7464 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C07 compound treatment 0.194 -0.0636 -0.91 0.233 -0.0237 -0.4 -0.9242 -0.9311 3125152 ChemDiv3_016563 COc1ccccc1NC(=O)CN2C=NS(=O)(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C08 mock treatment 0.041 -0.217 -3.1 0.239 -0.0177 -0.3 -2.4005 -0.7713 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C09 compound treatment 0.261 0.00341 0.05 0.2 -0.0567 -0.95 -0.6382 -0.67 3044501 ChemDiv3_016564 Cc1ccc(cc1)N2C(=O)N(CC(=O)c3ccccc3)c4ccccc4S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C10 mock treatment 0.04 -0.218 -3.11 0.214 -0.0427 -0.72 -2.7073 -0.8477 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C11 compound treatment 0.252 -0.00559 -0.08 0.042 -0.215 -3.6 -2.6044 -0.7226 3125153 ChemDiv3_016565 COc1ccc(CCNC(=O)c2ccc3c(=O)n4nc(C)sc4nc3c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C12 mock treatment 0.176 -0.0816 -1.17 0.226 -0.0307 -0.51 -1.1894 -0.9324 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C13 compound treatment 0.074 -0.184 -2.63 0.225 -0.0317 -0.53 -2.2329 -0.8334 3044503 ChemDiv3_016566 CN1CCSc2ccc(cc12)C(=O)Nc3ccc(Br)c(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C14 mock treatment 0.19 -0.0676 -0.97 0.225 -0.0317 -0.53 -1.0596 -0.9604 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C15 compound treatment 0.204 -0.0536 -0.77 0.214 -0.0427 -0.72 -1.0486 -0.9994 3125154 ChemDiv3_016567 CC(C)N1C(CCC1=O)C(=O)N2CCC3(CC2)OCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C16 mock treatment 0.231 -0.0266 -0.38 0.041 -0.216 -3.62 -2.8287 -0.7771 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C17 compound treatment 0.202 -0.0556 -0.8 0.227 -0.0297 -0.5 -0.9145 -0.9746 3125155 ChemDiv3_016568 CCOC(=O)N1CCC(CC1)NC(=O)CN2C(=O)C(CC)Oc3ccc(C)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C18 mock treatment 0.189 -0.0686 -0.98 0.055 -0.202 -3.39 -3.0873 -0.876 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C19 compound treatment 0.2 -0.0576 -0.82 0.229 -0.0277 -0.46 -0.911 -0.9633 3044505 ChemDiv3_016569 COc1ccc(CN2CC(CC2=O)C(=O)NCc3ccccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C20 mock treatment 0.199 -0.0586 -0.84 0.179 -0.0777 -1.3 -1.5145 -0.9772 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C21 compound treatment 0.181 -0.0766 -1.1 0.197 -0.0597 -1.0 -1.483 -0.999 3125156 ChemDiv3_016570 COC(CN(C)C(=O)CN1CCN(Cc2ccc(Cl)cc2)C1=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C22 mock treatment 0.192 -0.0656 -0.94 0.196 -0.0607 -1.02 -1.3836 -0.9992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C23 mock treatment 0.187 -0.0706 -1.01 0.183 -0.0737 -1.24 -1.5884 -0.9949 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 C24 mock treatment 0.2 -0.0576 -0.82 0.198 -0.0587 -0.98 -1.2789 -0.9961 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D01 mock treatment 0.231 -0.0266 -0.38 0.228 -0.0287 -0.48 -0.6093 -0.9932 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D02 mock treatment 0.225 -0.0326 -0.47 0.241 -0.0157 -0.26 -0.5157 -0.9634 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D03 mock treatment 0.256 -0.00159 -0.02 0.288 0.0313 0.53 0.3556 0.6759 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D04 mock treatment 0.27 0.0124 0.18 0.287 0.0303 0.51 0.4853 0.9006 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D05 mock treatment 0.295 0.0374 0.54 0.286 0.0293 0.49 0.7263 0.9991 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D06 mock treatment 0.27 0.0124 0.18 0.309 0.0523 0.88 0.7464 0.8332 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D07 mock treatment 0.27 0.0124 0.18 0.292 0.0353 0.59 0.5447 0.8802 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D08 mock treatment 0.254 -0.00359 -0.05 0.282 0.0253 0.42 0.2642 0.6172 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D09 mock treatment 0.302 0.0444 0.64 0.313 0.0563 0.95 1.1176 0.9813 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D10 mock treatment 0.275 0.0174 0.25 0.289 0.0323 0.54 0.5596 0.9377 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D11 mock treatment 0.304 0.0464 0.66 0.278 0.0213 0.36 0.7224 0.9579 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D12 mock treatment 0.254 -0.00359 -0.05 0.248 -0.00868 -0.15 -0.1394 -0.9019 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D13 mock treatment 0.264 0.00641 0.09 0.293 0.0363 0.61 0.4959 0.8044 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D14 mock treatment 0.241 -0.0166 -0.24 0.318 0.0613 1.03 0.5599 0.5302 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D15 mock treatment 0.262 0.00441 0.06 0.322 0.0653 1.1 0.8198 0.7466 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D16 mock treatment 0.392 0.134 1.92 0.446 0.189 3.18 3.6063 0.971 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D17 mock treatment 0.406 0.148 2.12 0.457 0.2 3.36 3.8784 0.9754 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D18 mock treatment 0.233 -0.0246 -0.35 0.221 -0.0357 -0.6 -0.6722 -0.9678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D19 mock treatment 0.283 0.0254 0.36 0.275 0.0183 0.31 0.4744 0.9965 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D20 mock treatment 0.321 0.0634 0.91 0.238 -0.0187 -0.31 0.4196 0.4372 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D21 mock treatment 0.248 -0.00959 -0.14 0.248 -0.00868 -0.15 -0.2 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D22 mock treatment 0.285 0.0274 0.39 0.268 0.0113 0.19 0.4115 0.9447 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D23 mock treatment 0.218 -0.0396 -0.57 0.215 -0.0417 -0.7 -0.8951 -0.9945 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 D24 mock treatment 0.191 -0.0666 -0.95 0.192 -0.0647 -1.09 -1.4412 -0.9979 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E01 compound treatment 0.234 -0.0236 -0.34 0.224 -0.0327 -0.55 -0.6265 -0.9728 3044506 ChemDiv3_016571 O=C(NCc1ccccc1)c2ccc(cc2)n3cnc4cccnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E02 compound treatment 0.201 -0.0566 -0.81 0.196 -0.0607 -1.02 -1.2925 -0.9935 3125157 ChemDiv3_016572 CN(CC(=O)Nc1ccc(C)c(F)c1)c2cc3OCC(=O)Nc3cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E03 compound treatment 0.244 -0.0136 -0.19 0.29 0.0333 0.56 0.258 0.4357 3044508 ChemDiv3_016573 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E04 compound treatment 0.239 -0.0186 -0.27 0.245 -0.0117 -0.2 -0.3267 -0.9888 3125158 ChemDiv3_016574 O=C(NCc1ccc(s1)S(=O)(=O)N2CCOCC2)c3cccnc3C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E05 compound treatment 0.21 -0.0476 -0.68 0.232 -0.0247 -0.41 -0.7743 -0.9717 3125159 ChemDiv3_016575 CC(CNC(=O)c1cc(n[nH]1)c2ccco2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E06 mock treatment 0.24 -0.0176 -0.25 0.211 -0.0457 -0.77 -0.7201 -0.8923 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E07 compound treatment 0.244 -0.0136 -0.19 0.253 -0.00368 -0.06 -0.1812 -0.8881 3044510 ChemDiv3_016576 CCCCN1C=NS(=O)(=O)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E08 mock treatment 0.276 0.0184 0.26 0.273 0.0163 0.27 0.3799 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E09 compound treatment 0.214 -0.0436 -0.62 0.215 -0.0417 -0.7 -0.9356 -0.9983 3044511 ChemDiv3_016577 Cc1ccc(C)c(c1)N2C(=O)Nc3ccccc3S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E10 mock treatment 0.238 -0.0196 -0.28 0.232 -0.0247 -0.41 -0.4911 -0.9819 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E11 compound treatment 0.247 -0.0106 -0.15 0.222 -0.0347 -0.58 -0.5187 -0.8624 3125160 ChemDiv3_016578 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)N4CCN(CC4)c5ccc(F)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E12 mock treatment 0.286 0.0284 0.41 0.269 0.0123 0.21 0.4335 0.9509 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E13 compound treatment 0.205 -0.0526 -0.75 0.177 -0.0797 -1.34 -1.4776 -0.963 3125161 ChemDiv3_016579 CC(=O)Nc1ccccc1c2nc3ccc(cc3[nH]c2=O)C(=O)NCc4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E14 mock treatment 0.274 0.0164 0.23 0.254 -0.00268 -0.05 0.1341 0.5612 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E15 compound treatment 0.256 -0.00159 -0.02 0.238 -0.0187 -0.31 -0.2378 -0.7564 3044513 ChemDiv3_016580 CC(C)N1C(CCC1=O)C(=O)NCCC2=CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E16 mock treatment 0.243 -0.0146 -0.21 0.279 0.0223 0.37 0.1173 0.2736 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E17 compound treatment 0.268 0.0104 0.15 0.217 -0.0397 -0.67 -0.3657 -0.5358 3125162 ChemDiv3_016581 COc1ccc(Br)cc1CNC(=O)C2CCC(=O)N2C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E18 mock treatment 0.246 -0.0116 -0.17 0.223 -0.0337 -0.57 -0.517 -0.8775 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E19 compound treatment 0.235 -0.0226 -0.32 0.225 -0.0317 -0.53 -0.6045 -0.9715 3044515 ChemDiv3_016582 O=C(C1CN(CCc2ccccc2)C(=O)C1)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E20 mock treatment 0.246 -0.0116 -0.17 0.223 -0.0337 -0.57 -0.517 -0.8775 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E21 compound treatment 0.237 -0.0206 -0.29 0.214 -0.0427 -0.72 -0.7148 -0.9229 3125163 ChemDiv3_016583 Cc1cc(Br)ccc1NC(=O)CCCc2c[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E22 mock treatment 0.219 -0.0386 -0.55 0.22 -0.0367 -0.62 -0.8257 -0.9985 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E23 mock treatment 0.194 -0.0636 -0.91 0.202 -0.0547 -0.92 -1.2921 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 E24 mock treatment 0.216 -0.0416 -0.59 0.208 -0.0487 -0.82 -0.9984 -0.9878 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F01 mock treatment 0.217 -0.0406 -0.58 0.211 -0.0457 -0.77 -0.9527 -0.9906 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F02 mock treatment 0.254 -0.00359 -0.05 0.212 -0.0447 -0.75 -0.5666 -0.7538 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F03 mock treatment 0.26 0.00241 0.03 0.273 0.0163 0.27 0.218 0.7899 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F04 mock treatment 0.23 -0.0276 -0.39 0.28 0.0233 0.39 -0.0023 -0.0042 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F05 mock treatment 0.293 0.0354 0.51 0.284 0.0273 0.46 0.6824 0.9988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F06 mock treatment 0.271 0.0134 0.19 0.288 0.0313 0.53 0.5073 0.9067 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F07 mock treatment 0.3 0.0424 0.61 0.332 0.0753 1.26 1.3228 0.9434 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F08 mock treatment 0.343 0.0854 1.22 0.318 0.0613 1.03 1.5916 0.9964 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F09 mock treatment 0.279 0.0214 0.31 0.304 0.0473 0.79 0.7781 0.9142 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F10 mock treatment 0.359 0.101 1.45 0.303 0.0463 0.78 1.5754 0.9573 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F11 mock treatment 0.348 0.0904 1.29 0.272 0.0153 0.26 1.0962 0.8314 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F12 mock treatment 0.288 0.0304 0.43 0.342 0.0853 1.43 1.3201 0.8821 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F13 mock treatment 0.345 0.0874 1.25 0.336 0.0793 1.33 1.8254 0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F14 mock treatment 0.307 0.0494 0.71 0.265 0.00832 0.14 0.5985 0.8307 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F15 mock treatment 0.348 0.0904 1.29 0.331 0.0743 1.25 1.7964 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F16 mock treatment 0.375 0.117 1.68 0.32 0.0633 1.06 1.939 0.9756 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F17 mock treatment 0.395 0.137 1.97 0.355 0.0983 1.65 2.5566 0.9962 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F18 mock treatment 0.376 0.118 1.69 0.33 0.0733 1.23 2.0678 0.9877 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F19 mock treatment 0.388 0.13 1.87 0.341 0.0843 1.42 2.3197 0.9907 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F20 mock treatment 0.431 0.173 2.48 0.454 0.197 3.31 4.0957 0.9899 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F21 mock treatment 0.33 0.0724 1.04 0.283 0.0263 0.44 1.0447 0.9278 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F22 mock treatment 0.277 0.0194 0.28 0.236 -0.0207 -0.35 -0.0491 -0.1106 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F23 mock treatment 0.224 -0.0336 -0.48 0.247 -0.00968 -0.16 -0.4546 -0.8964 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 F24 mock treatment 0.215 -0.0426 -0.61 0.206 -0.0507 -0.85 -1.0323 -0.9866 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G01 compound treatment 0.208 -0.0496 -0.71 0.211 -0.0457 -0.77 -1.0437 -0.9992 3044566 ChemDiv3_016584 O=C(NC1CCCCCC1)c2ccc(cc2)n3cnc4cccnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G02 compound treatment 0.203 -0.0546 -0.78 0.234 -0.0227 -0.38 -0.8213 -0.9455 3044567 ChemDiv3_016585 CN(CC(=O)N1CCN(CC1)c2ccccc2F)c3cc4OCC(=O)Nc4cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G03 compound treatment 0.246 -0.0116 -0.17 0.269 0.0123 0.21 0.029 0.1093 3044569 ChemDiv3_016586 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G04 compound treatment 0.216 -0.0416 -0.59 0.246 -0.0107 -0.18 -0.5474 -0.8811 3044570 ChemDiv3_016587 COC(=O)CN1C(=O)CSc2cc(ccc12)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G05 compound treatment 0.249 -0.00859 -0.12 0.243 -0.0137 -0.23 -0.2493 -0.957 3044572 ChemDiv3_016588 CCOC(=O)C1CCN(CC1)C(=O)c2cc(n[nH]2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G06 mock treatment 0.274 0.0164 0.23 0.244 -0.0127 -0.21 0.0155 0.0488 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G07 compound treatment 0.273 0.0154 0.22 0.299 0.0423 0.71 0.6581 0.8849 3044573 ChemDiv3_016589 COc1ccc(cc1)N2C(=O)N(Cc3ccccc3)c4ccccc4S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G08 mock treatment 0.31 0.0524 0.75 0.258 0.00132 0.02 0.5457 0.7276 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G09 compound treatment 0.292 0.0344 0.49 0.244 -0.0127 -0.21 0.1975 0.3683 3044575 ChemDiv3_016590 Cc1cccc(c1)N2C(=O)N(Cc3ccccc3)c4ccccc4S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G10 mock treatment 0.306 0.0484 0.69 0.29 0.0333 0.56 0.885 0.9944 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G11 compound treatment 0.188 -0.0696 -1.0 0.164 -0.0927 -1.56 -1.8038 -0.9767 3125164 ChemDiv3_016591 COc1ccc(Nc2nn3c(=O)c4ccccc4nc3s2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G12 mock treatment 0.26 0.00241 0.03 0.257 3.17E-4 0.01 0.0281 0.8067 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G13 compound treatment 0.279 0.0214 0.31 0.245 -0.0117 -0.2 0.0779 0.2142 3125276 ChemDiv3_016592 O=C(NC1CCCC1)C2N(Cc3ccccc3)C(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G14 mock treatment 0.259 0.00141 0.02 0.233 -0.0237 -0.4 -0.2668 -0.6704 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G15 compound treatment 0.289 0.0314 0.45 0.286 0.0293 0.49 0.6656 0.999 3044577 ChemDiv3_016593 CC(C)N1C(CCC1=O)C(=O)N2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G16 mock treatment 0.259 0.00141 0.02 0.286 0.0293 0.49 0.3622 0.7355 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G17 compound treatment 0.265 0.00741 0.11 0.277 0.0203 0.34 0.3161 0.8851 3125277 ChemDiv3_016594 CC(C)N1C(CCC1=O)C(=O)NCc2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G18 mock treatment 0.256 -0.00159 -0.02 0.242 -0.0147 -0.25 -0.1903 -0.7691 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G19 compound treatment 0.238 -0.0196 -0.28 0.244 -0.0127 -0.21 -0.3487 -0.9908 3125278 ChemDiv3_016595 COc1ccc(CCNC(=O)C2CCC(=O)N2CCc3ccccc3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G20 mock treatment 0.233 -0.0246 -0.35 0.223 -0.0337 -0.57 -0.6485 -0.9739 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G21 compound treatment 0.237 -0.0206 -0.29 0.22 -0.0367 -0.62 -0.6436 -0.943 3044579 ChemDiv3_016596 Fc1cc(Cl)ccc1NC(=O)CCCc2c[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G22 mock treatment 0.229 -0.0286 -0.41 0.226 -0.0307 -0.51 -0.6533 -0.9935 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G23 mock treatment 0.197 -0.0606 -0.87 0.23 -0.0267 -0.45 -0.9295 -0.9528 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 G24 mock treatment 0.17 -0.0876 -1.25 0.211 -0.0457 -0.77 -1.4281 -0.9722 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H01 mock treatment 0.35 0.0924 1.32 0.232 -0.0247 -0.41 0.6417 0.4633 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H02 mock treatment 0.215 -0.0426 -0.61 0.241 -0.0157 -0.26 -0.6169 -0.9296 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H03 mock treatment 0.289 0.0314 0.45 0.232 -0.0247 -0.41 0.0248 0.0405 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H04 mock treatment 0.281 0.0234 0.33 0.257 3.17E-4 0.01 0.2405 0.7183 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H05 mock treatment 0.276 0.0184 0.26 0.276 0.0193 0.32 0.4155 0.9947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H06 mock treatment 0.26 0.00241 0.03 0.305 0.0483 0.81 0.5978 0.7365 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H07 mock treatment 0.305 0.0474 0.68 0.32 0.0633 1.06 1.231 0.9765 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H08 mock treatment 0.3 0.0424 0.61 0.321 0.0643 1.08 1.1923 0.9629 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H09 mock treatment 0.339 0.0814 1.16 0.253 -0.00368 -0.06 0.7797 0.6686 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H10 mock treatment 0.321 0.0634 0.91 0.322 0.0653 1.1 1.4165 0.9956 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H11 mock treatment 0.333 0.0754 1.08 0.355 0.0983 1.65 1.9296 0.9788 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H12 mock treatment 0.361 0.103 1.48 0.351 0.0943 1.58 2.1653 0.9994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H13 mock treatment 0.33 0.0724 1.04 0.33 0.0733 1.23 1.6025 0.9963 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H14 mock treatment 0.331 0.0734 1.05 0.317 0.0603 1.01 1.4583 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H15 mock treatment 0.427 0.169 2.42 0.431 0.174 2.93 3.7823 0.9956 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H16 mock treatment 0.327 0.0694 0.99 0.316 0.0593 1.0 1.406 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H17 mock treatment 0.424 0.166 2.38 0.45 0.193 3.24 3.9774 0.9884 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H18 mock treatment 0.274 0.0164 0.23 0.263 0.00632 0.11 0.241 0.9355 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H19 mock treatment 0.319 0.0614 0.88 0.272 0.0153 0.26 0.8029 0.8773 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H20 mock treatment 0.296 0.0384 0.55 0.278 0.0213 0.36 0.6415 0.9784 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H21 mock treatment 0.348 0.0904 1.29 0.29 0.0333 0.56 1.3098 0.9297 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H22 mock treatment 0.3 0.0424 0.61 0.287 0.0303 0.51 0.7888 0.9962 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H23 mock treatment 0.24 -0.0176 -0.25 0.195 -0.0617 -1.04 -0.91 -0.8541 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 H24 mock treatment 0.191 -0.0666 -0.95 0.216 -0.0407 -0.68 -1.1563 -0.9867 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I01 compound treatment 0.225 -0.0326 -0.47 0.236 -0.0207 -0.35 -0.5751 -0.9895 3125279 ChemDiv3_016597 O=C(NCC1CCCO1)c2ccc(cc2)n3cnc4cccnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I02 compound treatment 0.223 -0.0346 -0.49 0.22 -0.0367 -0.62 -0.7852 -0.9941 3044580 ChemDiv3_016598 CN(CC(=O)N1CCc2ccccc2C1)c3cc4OCC(=O)Nc4cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I03 compound treatment 0.245 -0.0126 -0.18 0.18 -0.0767 -1.29 -1.0374 -0.7983 3125280 ChemDiv3_016599 Cc1cc(on1)c2ccc(cc2)S(=O)(=O)Nc3ccc(cc3)c4ccno4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I04 mock treatment 0.268 0.0104 0.15 0.264 0.00732 0.12 0.1921 0.9954 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I05 compound treatment 0.244 -0.0136 -0.19 0.263 0.00632 0.11 -0.0625 -0.2822 3044582 ChemDiv3_016600 CCCNC(=O)c1cc(n[nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I06 mock treatment 0.256 -0.00159 -0.02 0.242 -0.0147 -0.25 -0.1903 -0.7691 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I07 compound treatment 0.268 0.0104 0.15 0.305 0.0483 0.81 0.6787 0.8232 3125281 ChemDiv3_016601 COc1ccccc1C(=O)CN2C=NS(=O)(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I08 mock treatment 0.269 0.0114 0.16 0.274 0.0173 0.29 0.3209 0.9628 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I09 compound treatment 0.265 0.00741 0.11 0.246 -0.0107 -0.18 -0.0518 -0.2489 3125282 ChemDiv3_016602 COc1ccc(CNC(=O)c2ccc(CN3C(=NS(=O)(=O)c4ccccc34)C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I10 mock treatment 0.276 0.0184 0.26 0.273 0.0163 0.27 0.3799 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I11 compound treatment 0.256 -0.00159 -0.02 0.233 -0.0237 -0.4 -0.2971 -0.7463 1459368 ChemDiv3_016603 COc1cc2CCN(C(C)c2cc1OC)c3ncnc4n(ncc34)c5cccc(C)c5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I12 mock treatment 0.253 -0.00459 -0.07 0.255 -0.00168 -0.03 -0.0664 -0.929 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I13 compound treatment 0.247 -0.0106 -0.15 0.214 -0.0427 -0.72 -0.6137 -0.8381 3125283 ChemDiv3_016604 O=C(NC1CCCC1)C2N(C3CCCC3)C(=O)c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I14 mock treatment 0.237 -0.0206 -0.29 0.297 0.0403 0.68 0.2702 0.3662 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I15 compound treatment 0.23 -0.0276 -0.39 0.261 0.00432 0.07 -0.2278 -0.5678 3044585 ChemDiv3_016605 CCOC(=O)N1CCN(CC1)C(=O)C2CCC(=O)N2C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I16 mock treatment 0.271 0.0134 0.19 0.247 -0.00968 -0.16 0.0207 0.0824 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I17 compound treatment 0.255 -0.00259 -0.04 0.219 -0.0377 -0.63 -0.4734 -0.7472 3125284 ChemDiv3_016606 O=C(NC1CC1)C2CCC(=O)N2C3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I18 mock treatment 0.218 -0.0396 -0.57 0.2 -0.0567 -0.95 -1.0731 -0.9693 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I19 compound treatment 0.257 -5.89E-4 -0.01 0.231 -0.0257 -0.43 -0.3108 -0.7208 3125285 ChemDiv3_016607 O=C(NCc1cccnc1)C2CCC(=O)N2CCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I20 mock treatment 0.238 -0.0196 -0.28 0.219 -0.0377 -0.63 -0.6454 -0.9329 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I21 compound treatment 0.194 -0.0636 -0.91 0.187 -0.0697 -1.17 -1.4702 -0.9923 3044587 ChemDiv3_016608 COc1ccc(NC(=O)CCCc2c[nH]c3ccccc23)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I22 mock treatment 0.2 -0.0576 -0.82 0.184 -0.0727 -1.22 -1.4451 -0.9817 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I23 mock treatment 0.194 -0.0636 -0.91 0.2 -0.0567 -0.95 -1.3159 -0.9997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 I24 mock treatment 0.205 -0.0526 -0.75 0.212 -0.0447 -0.75 -1.0622 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J01 mock treatment 0.224 -0.0336 -0.48 0.408 0.151 2.54 1.4561 0.5633 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J02 mock treatment 0.227 -0.0306 -0.44 0.258 0.00132 0.02 -0.2938 -0.6705 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J03 mock treatment 0.253 -0.00459 -0.07 0.239 -0.0177 -0.3 -0.2563 -0.8431 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J04 mock treatment 0.259 0.00141 0.02 0.236 -0.0207 -0.35 -0.2312 -0.6649 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J05 mock treatment 0.262 0.00441 0.06 0.247 -0.00968 -0.16 -0.0703 -0.4033 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J06 mock treatment 0.301 0.0434 0.62 0.298 0.0413 0.69 0.9294 0.9985 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J07 mock treatment 0.291 0.0334 0.48 0.277 0.0203 0.34 0.579 0.9863 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J08 mock treatment 0.307 0.0494 0.71 0.302 0.0453 0.76 1.0376 0.9993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J09 mock treatment 0.294 0.0364 0.52 0.438 0.181 3.04 2.5202 0.8163 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J10 mock treatment 0.285 0.0274 0.39 0.322 0.0653 1.1 1.0524 0.9039 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J11 mock treatment 0.28 0.0224 0.32 0.363 0.106 1.78 1.4884 0.821 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J12 mock treatment 0.329 0.0714 1.02 0.348 0.0913 1.53 1.806 0.9806 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J13 mock treatment 0.329 0.0714 1.02 0.29 0.0333 0.56 1.1177 0.9598 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J14 mock treatment 0.328 0.0704 1.01 0.329 0.0723 1.21 1.5704 0.9957 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J15 mock treatment 0.34 0.0824 1.18 0.331 0.0743 1.25 1.7155 0.9996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J16 mock treatment 0.31 0.0524 0.75 0.361 0.104 1.75 1.7681 0.9284 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J17 mock treatment 0.301 0.0434 0.62 0.274 0.0173 0.29 0.6446 0.9402 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J18 mock treatment 0.306 0.0484 0.69 0.32 0.0633 1.06 1.2411 0.9785 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J19 mock treatment 0.281 0.0234 0.33 0.301 0.0443 0.74 0.7627 0.9351 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J20 mock treatment 0.329 0.0714 1.02 0.296 0.0393 0.66 1.1889 0.9777 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J21 mock treatment 0.273 0.0154 0.22 0.299 0.0423 0.71 0.6581 0.8849 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J22 mock treatment 0.253 -0.00459 -0.07 0.277 0.0203 0.34 0.1947 0.5607 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J23 mock treatment 0.215 -0.0426 -0.61 0.204 -0.0527 -0.88 -1.056 -0.9835 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 J24 mock treatment 0.225 -0.0326 -0.47 0.185 -0.0717 -1.2 -1.1804 -0.9148 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K01 compound treatment 0.222 -0.0356 -0.51 0.251 -0.00568 -0.1 -0.4274 -0.8252 3125286 ChemDiv3_016609 O=C(Nc1ccccc1)N2CCC(=CC2)c3c[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K02 compound treatment 0.244 -0.0136 -0.19 0.245 -0.0117 -0.2 -0.2761 -1.0 3044589 ChemDiv3_016610 O=C1CN(c2ccccc2N1)S(=O)(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K03 compound treatment 0.273 0.0154 0.22 0.268 0.0113 0.19 0.2902 0.9973 3125287 ChemDiv3_016611 CN(CC(=O)Nc1cccc(C)c1)S(=O)(=O)c2ccc(cc2)c3cc(C)no3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K04 mock treatment 0.246 -0.0116 -0.17 0.268 0.0113 0.19 0.0171 0.0678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K05 compound treatment 0.277 0.0194 0.28 0.237 -0.0197 -0.33 -0.0373 -0.0864 3125288 ChemDiv3_016612 CC1CCC(CC1)NC(=O)c2cc(n[nH]2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K06 mock treatment 0.232 -0.0256 -0.37 0.263 0.00632 0.11 -0.1838 -0.4824 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K07 compound treatment 0.217 -0.0406 -0.58 0.267 0.0103 0.17 -0.2881 -0.4755 3125289 ChemDiv3_016613 COc1ccc(CCNC(=O)CN2C=NS(=O)(=O)c3ccccc23)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K08 mock treatment 0.251 -0.00659 -0.09 0.253 -0.00368 -0.06 -0.1104 -0.9791 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K09 compound treatment 0.228 -0.0296 -0.42 0.252 -0.00468 -0.08 -0.3549 -0.8243 3043570 ChemDiv3_016614 Cc1ccc(CNC(=O)CSC2=NS(=O)(=O)c3ccccc3N2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K10 mock treatment 0.237 -0.0206 -0.29 0.25 -0.00668 -0.11 -0.2876 -0.9125 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K11 compound treatment 0.232 -0.0256 -0.37 0.228 -0.0287 -0.48 -0.5992 -0.9909 3043571 ChemDiv3_016615 COc1cccc2cc(CC(=O)O)oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K12 mock treatment 0.274 0.0164 0.23 0.247 -0.00968 -0.16 0.0511 0.1789 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K13 compound treatment 0.232 -0.0256 -0.37 0.261 0.00432 0.07 -0.2076 -0.5563 3043573 ChemDiv3_016616 CCC(C)NC(=O)C1N(Cc2ccccc2OC)C(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K14 mock treatment 0.238 -0.0196 -0.28 0.273 0.0163 0.27 -0.0045 -0.0114 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K15 compound treatment 0.304 0.0464 0.66 0.232 -0.0247 -0.41 0.1765 0.2255 3043575 ChemDiv3_016617 COc1ccc(CCNC(=O)C2N(C3CCCCCC3)C(=O)c4ccccc24)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K16 mock treatment 0.231 -0.0266 -0.38 0.221 -0.0357 -0.6 -0.6924 -0.976 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K17 compound treatment 0.276 0.0184 0.26 0.214 -0.0427 -0.72 -0.3204 -0.4197 3043576 ChemDiv3_016618 O=C(C1CN(C2CCCC2)C(=O)C1)N3CCC4(CC3)OCCO4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K18 mock treatment 0.212 -0.0456 -0.65 0.206 -0.0507 -0.85 -1.0626 -0.9914 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K19 compound treatment 0.231 -0.0266 -0.38 0.217 -0.0397 -0.67 -0.7399 -0.9647 3043578 ChemDiv3_016619 O=C(C1CCC(=O)N1C2CCCC2)N3CCN(CC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K20 mock treatment 0.243 -0.0146 -0.21 0.236 -0.0207 -0.35 -0.393 -0.9703 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K21 compound treatment 0.232 -0.0256 -0.37 0.204 -0.0527 -0.88 -0.8841 -0.9238 3043580 ChemDiv3_016620 COc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(OC)nc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K22 mock treatment 0.178 -0.0796 -1.14 0.245 -0.0117 -0.2 -0.9436 -0.8169 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K23 mock treatment 0.195 -0.0626 -0.9 0.184 -0.0727 -1.22 -1.4957 -0.9884 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 K24 mock treatment 0.175 -0.0826 -1.18 0.193 -0.0637 -1.07 -1.5911 -0.9988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L01 mock treatment 0.223 -0.0346 -0.49 0.431 0.174 2.93 1.719 0.5793 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L02 mock treatment 0.261 0.00341 0.05 0.218 -0.0387 -0.65 -0.4246 -0.6521 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L03 mock treatment 0.435 0.177 2.54 0.423 0.166 2.79 3.7682 0.9989 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L04 mock treatment 0.293 0.0354 0.51 0.225 -0.0317 -0.53 -0.0179 -0.0243 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L05 mock treatment 0.242 -0.0156 -0.22 0.28 0.0233 0.39 0.1191 0.2643 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L06 mock treatment 0.311 0.0534 0.76 0.266 0.00932 0.16 0.6508 0.8345 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L07 mock treatment 0.325 0.0674 0.96 0.266 0.00932 0.16 0.7924 0.8112 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L08 mock treatment 0.309 0.0514 0.74 0.293 0.0363 0.61 0.951 0.9957 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L09 mock treatment 0.28 0.0224 0.32 0.34 0.0833 1.4 1.2155 0.8472 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L10 mock treatment 0.285 0.0274 0.39 0.318 0.0613 1.03 1.005 0.9125 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L11 mock treatment 0.315 0.0574 0.82 0.305 0.0483 0.81 1.1541 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L12 mock treatment 0.294 0.0364 0.52 0.323 0.0663 1.11 1.1553 0.9401 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L13 mock treatment 0.309 0.0514 0.74 0.306 0.0493 0.83 1.1053 0.9983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L14 mock treatment 0.243 -0.0146 -0.21 0.277 0.0203 0.34 0.0936 0.234 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L15 mock treatment 0.295 0.0374 0.54 0.293 0.0363 0.61 0.8094 0.9979 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L16 mock treatment 0.243 -0.0146 -0.21 0.322 0.0653 1.1 0.6276 0.5624 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L17 mock treatment 0.335 0.0774 1.11 0.331 0.0743 1.25 1.6649 0.9982 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L18 mock treatment 0.283 0.0254 0.36 0.311 0.0543 0.91 0.9016 0.9187 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L19 mock treatment 0.331 0.0734 1.05 0.328 0.0713 1.2 1.5889 0.9979 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L20 mock treatment 0.432 0.174 2.49 0.418 0.161 2.71 3.6786 0.9992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L21 mock treatment 0.376 0.118 1.69 0.245 -0.0117 -0.2 1.059 0.6211 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L22 mock treatment 0.282 0.0244 0.35 0.31 0.0533 0.89 0.8797 0.9158 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L23 mock treatment 0.227 -0.0306 -0.44 0.237 -0.0197 -0.33 -0.543 -0.9904 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 L24 mock treatment 0.218 -0.0396 -0.57 0.219 -0.0377 -0.63 -0.8476 -0.9985 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M01 compound treatment 0.231 -0.0266 -0.38 0.214 -0.0427 -0.72 -0.7755 -0.9561 3125290 ChemDiv3_016621 Cc1ccc(CNC(=O)N2CCC(=CC2)c3c[nH]c4ccccc34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M02 compound treatment 0.257 -5.89E-4 -0.01 0.253 -0.00368 -0.06 -0.0497 -0.7962 3125291 ChemDiv3_016622 CC(CC(=O)N1CCOCC1)S(=O)(=O)c2ccc3NC(=O)CSc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M03 compound treatment 0.231 -0.0266 -0.38 0.254 -0.00268 -0.05 -0.3008 -0.7853 3043582 ChemDiv3_016623 COc1cccc(NS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M04 mock treatment 0.248 -0.00959 -0.14 0.248 -0.00868 -0.15 -0.2 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M05 compound treatment 0.223 -0.0346 -0.49 0.263 0.00632 0.11 -0.2749 -0.5432 3125292 ChemDiv3_016624 Fc1ccccc1N2CCN(CCNC(=O)c3cc(n[nH]3)c4ccccc4)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M06 mock treatment 0.25 -0.00759 -0.11 0.227 -0.0297 -0.5 -0.429 -0.8414 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M07 compound treatment 0.254 -0.00359 -0.05 0.203 -0.0537 -0.9 -0.6734 -0.7462 3043584 ChemDiv3_016625 Cc1ccc(cc1)N2C(=O)N(CC(=O)C(C)(C)C)c3ccccc3S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M08 mock treatment 0.258 4.11E-4 0.01 0.268 0.0113 0.19 0.1385 0.7286 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M09 compound treatment 0.229 -0.0286 -0.41 0.238 -0.0187 -0.31 -0.5109 -0.9914 3125293 ChemDiv3_016626 CCOC(=O)CN1C(=O)N(c2ccccc2OC)S(=O)(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M10 mock treatment 0.262 0.00441 0.06 0.277 0.0203 0.34 0.2857 0.8239 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M11 compound treatment 0.15 -0.108 -1.54 0.191 -0.0657 -1.1 -1.8677 -0.9866 3043586 ChemDiv3_016627 Cc1ccc2OCC(=O)N(CCCC(=O)O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M12 mock treatment 0.26 0.00241 0.03 0.268 0.0113 0.19 0.1587 0.822 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M13 compound treatment 0.218 -0.0396 -0.57 0.229 -0.0277 -0.46 -0.729 -0.9952 3125294 ChemDiv3_016628 Cc1ccc(CNC(=O)CNc2ccccc2c3nc4ccccc4[nH]c3=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M14 mock treatment 0.248 -0.00959 -0.14 0.243 -0.0137 -0.23 -0.2594 -0.9697 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M15 compound treatment 0.255 -0.00259 -0.04 0.277 0.0203 0.34 0.2149 0.6266 3125295 ChemDiv3_016629 COc1ccc(CCNC(=O)C2N(CCC(C)C)C(=O)c3ccccc23)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M16 mock treatment 0.239 -0.0186 -0.27 0.218 -0.0387 -0.65 -0.6471 -0.9223 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M17 compound treatment 0.243 -0.0146 -0.21 0.208 -0.0487 -0.82 -0.7253 -0.8601 3043589 ChemDiv3_016630 Fc1ccc(cc1)N2CCN(CC2)C(=O)C3CN(C4CCCC4)C(=O)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M18 mock treatment 0.216 -0.0416 -0.59 0.22 -0.0367 -0.62 -0.856 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M19 compound treatment 0.221 -0.0366 -0.52 0.242 -0.0147 -0.25 -0.5443 -0.941 3125296 ChemDiv3_016631 CC(N1CC(CC1=O)C(=O)N2CCN(CC2)c3ccc(F)cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M20 mock treatment 0.237 -0.0206 -0.29 0.192 -0.0647 -1.09 -0.9759 -0.8676 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M21 compound treatment 0.222 -0.0356 -0.51 0.209 -0.0477 -0.8 -0.9259 -0.9761 3043590 ChemDiv3_016632 Cc1cccc(n1)N2CCN(CC2)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M22 mock treatment 0.25 -0.00759 -0.11 0.218 -0.0387 -0.65 -0.5359 -0.814 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M23 mock treatment 0.221 -0.0366 -0.52 0.23 -0.0267 -0.45 -0.6867 -0.997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 M24 mock treatment 0.223 -0.0346 -0.49 0.208 -0.0487 -0.82 -0.9276 -0.9711 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N01 mock treatment 0.205 -0.0526 -0.75 0.444 0.187 3.14 1.6912 0.5232 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N02 mock treatment 0.444 0.186 2.67 0.421 0.164 2.76 3.8355 0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N03 mock treatment 0.234 -0.0236 -0.34 0.213 -0.0437 -0.73 -0.757 -0.938 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N04 mock treatment 0.235 -0.0226 -0.32 0.231 -0.0257 -0.43 -0.5333 -0.9899 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N05 mock treatment 0.237 -0.0206 -0.29 0.278 0.0213 0.36 0.0447 0.0966 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N06 mock treatment 0.269 0.0114 0.16 0.212 -0.0447 -0.75 -0.4149 -0.5406 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N07 mock treatment 0.267 0.00941 0.13 0.231 -0.0257 -0.43 -0.2096 -0.4642 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N08 mock treatment 0.422 0.164 2.35 0.432 0.175 2.94 3.7436 0.9938 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N09 mock treatment 0.253 -0.00459 -0.07 0.272 0.0153 0.26 0.1354 0.5102 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N10 mock treatment 0.441 0.183 2.62 0.434 0.177 2.98 3.9595 0.998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N11 mock treatment 0.272 0.0144 0.21 0.237 -0.0197 -0.33 -0.0878 -0.2256 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N12 mock treatment 0.25 -0.00759 -0.11 0.253 -0.00368 -0.06 -0.1205 -0.9644 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N13 mock treatment 0.231 -0.0266 -0.38 0.252 -0.00468 -0.08 -0.3245 -0.8356 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N14 mock treatment 0.224 -0.0336 -0.48 0.272 0.0153 0.26 -0.1579 -0.2899 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N15 mock treatment 0.437 0.179 2.57 0.43 0.173 2.91 3.8715 0.998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N16 mock treatment 0.215 -0.0426 -0.61 0.207 -0.0497 -0.83 -1.0204 -0.9881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N17 mock treatment 0.311 0.0534 0.76 0.294 0.0373 0.63 0.9831 0.9951 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N18 mock treatment 0.227 -0.0306 -0.44 0.278 0.0213 0.36 -0.0564 -0.0998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N19 mock treatment 0.226 -0.0316 -0.45 0.203 -0.0537 -0.9 -0.9566 -0.9491 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N20 mock treatment 0.41 0.152 2.18 0.43 0.173 2.91 3.5985 0.9899 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N21 mock treatment 0.272 0.0144 0.21 0.236 -0.0207 -0.35 -0.0997 -0.247 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N22 mock treatment 0.229 -0.0286 -0.41 0.246 -0.0107 -0.18 -0.4159 -0.9315 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N23 mock treatment 0.212 -0.0456 -0.65 0.206 -0.0507 -0.85 -1.0626 -0.9914 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 N24 mock treatment 0.203 -0.0546 -0.78 0.21 -0.0467 -0.78 -1.1062 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O01 compound treatment 0.236 -0.0216 -0.31 0.241 -0.0157 -0.26 -0.4045 -0.9968 3125297 ChemDiv3_016633 Cc1oc(nc1COc2ccc(C)cc2)c3ccc(cc3)C(=O)NC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O02 compound treatment 0.223 -0.0346 -0.49 0.204 -0.0527 -0.88 -0.9751 -0.9624 3043592 ChemDiv3_016634 COC(=O)Cn1cc(cc1C(=O)OC)S(=O)(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O03 compound treatment 0.222 -0.0356 -0.51 0.202 -0.0547 -0.92 -1.0089 -0.9613 3125298 ChemDiv3_016635 O=C1N(Cc2ccc(s2)S(=O)(=O)NCCc3ccccc3)C(=O)c4ncccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O04 mock treatment 0.222 -0.0356 -0.51 0.225 -0.0317 -0.53 -0.736 -0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O05 compound treatment 0.208 -0.0496 -0.71 0.26 0.00332 0.06 -0.4622 -0.6496 3125299 ChemDiv3_016636 COc1ccc(NC(=O)CCS(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O06 mock treatment 0.198 -0.0596 -0.85 0.212 -0.0447 -0.75 -1.133 -0.998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O07 compound treatment 0.204 -0.0536 -0.77 0.245 -0.0117 -0.2 -0.6807 -0.8603 3043644 ChemDiv3_016637 CN1C(=O)N(c2ccc(C)cc2)S(=O)(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O08 mock treatment 0.248 -0.00959 -0.14 0.209 -0.0477 -0.8 -0.6629 -0.8164 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O09 compound treatment 0.201 -0.0566 -0.81 0.218 -0.0387 -0.65 -1.0315 -0.994 3125300 ChemDiv3_016638 Cc1nn2c(=O)c3ccc(cc3nc2s1)C(=O)NCc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O10 mock treatment 0.216 -0.0416 -0.59 0.198 -0.0587 -0.98 -1.1171 -0.9708 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O11 compound treatment 0.198 -0.0596 -0.85 0.234 -0.0227 -0.38 -0.8719 -0.934 3043646 ChemDiv3_016639 CCOC(=O)CN1C(=O)/C(=C/c2ccc(Cl)cc2)/Oc3ccc(cc13)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O12 mock treatment 0.217 -0.0406 -0.58 0.213 -0.0437 -0.73 -0.929 -0.9933 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O13 compound treatment 0.218 -0.0396 -0.57 0.207 -0.0497 -0.83 -0.9901 -0.9822 3125301 ChemDiv3_016640 CC(C)N1C(CCC1=O)C(=O)N2CCN(C(C)C2)c3cccc(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O14 mock treatment 0.213 -0.0446 -0.64 0.239 -0.0177 -0.3 -0.6609 -0.9394 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O15 compound treatment 0.219 -0.0386 -0.55 0.222 -0.0347 -0.58 -0.8019 -0.9996 3125302 ChemDiv3_016641 CC1(CCC(=O)N1CCC2=CCCCC2)C(=O)NC3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O16 mock treatment 0.191 -0.0666 -0.95 0.203 -0.0537 -0.9 -1.3106 -0.9996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O17 compound treatment 0.187 -0.0706 -1.01 0.203 -0.0537 -0.9 -1.3511 -0.9984 3043648 ChemDiv3_016642 O=C(NCc1ccccn1)C2CCC(=O)N2C3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O18 mock treatment 0.216 -0.0416 -0.59 0.213 -0.0437 -0.73 -0.9391 -0.9946 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O19 compound treatment 0.229 -0.0286 -0.41 0.201 -0.0557 -0.93 -0.95 -0.9313 3125303 ChemDiv3_016643 COC(CNC(=O)C1CCC(=O)N1Cc2ccc(F)cc2)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O20 mock treatment 0.23 -0.0276 -0.39 0.218 -0.0387 -0.65 -0.7381 -0.9715 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O21 compound treatment 0.23 -0.0276 -0.39 0.221 -0.0357 -0.6 -0.7025 -0.9795 3043650 ChemDiv3_016644 CN1C(=O)C(C)(C)c2cc(ccc12)S(=O)(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O22 mock treatment 0.227 -0.0306 -0.44 0.2 -0.0567 -0.95 -0.9821 -0.9379 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O23 mock treatment 0.18 -0.0776 -1.11 0.196 -0.0607 -1.02 -1.5049 -0.9991 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 O24 mock treatment 0.184 -0.0736 -1.05 0.224 -0.0327 -0.55 -1.1322 -0.9539 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P01 mock treatment 0.4 0.142 2.04 0.423 0.166 2.79 3.4142 0.988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P02 mock treatment 0.417 0.159 2.28 0.371 0.114 1.92 2.969 0.9963 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P03 mock treatment 0.251 -0.00659 -0.09 0.215 -0.0417 -0.7 -0.5613 -0.7952 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P04 mock treatment 0.242 -0.0156 -0.22 0.223 -0.0337 -0.57 -0.5574 -0.9172 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P05 mock treatment 0.251 -0.00659 -0.09 0.25 -0.00668 -0.11 -0.146 -0.9963 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P06 mock treatment 0.419 0.161 2.31 0.234 -0.0227 -0.38 1.3633 0.5826 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P07 mock treatment 0.382 0.124 1.78 0.424 0.167 2.81 3.2441 0.9758 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P08 mock treatment 0.45 0.192 2.75 0.231 -0.0257 -0.43 1.6413 0.5892 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P09 mock treatment 0.267 0.00941 0.13 0.23 -0.0267 -0.45 -0.2215 -0.4736 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P10 mock treatment 0.443 0.185 2.65 0.411 0.154 2.59 3.7067 0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P11 mock treatment 0.446 0.188 2.69 0.41 0.153 2.57 3.7252 0.9997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P12 mock treatment 0.413 0.155 2.22 0.4 0.143 2.41 3.2728 0.9992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P13 mock treatment 0.453 0.195 2.8 0.261 0.00432 0.07 2.0277 0.7252 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P14 mock treatment 0.239 -0.0186 -0.27 0.435 0.178 2.99 1.9283 0.6418 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P15 mock treatment 0.216 -0.0416 -0.59 0.431 0.174 2.93 1.6482 0.552 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P16 mock treatment 0.415 0.157 2.25 0.43 0.173 2.91 3.649 0.992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P17 mock treatment 0.265 0.00741 0.11 0.428 0.171 2.88 2.1082 0.7327 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P18 mock treatment 0.462 0.204 2.92 0.447 0.19 3.19 4.3262 0.999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P19 mock treatment 0.454 0.196 2.81 0.462 0.205 3.45 4.4233 0.9949 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P20 mock treatment 0.437 0.179 2.57 0.45 0.193 3.24 4.1089 0.9933 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P21 mock treatment 0.343 0.0854 1.22 0.223 -0.0337 -0.57 0.4641 0.3448 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P22 mock treatment 0.43 0.172 2.47 0.466 0.209 3.51 4.228 0.985 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P23 mock treatment 0.243 -0.0146 -0.21 0.248 -0.00868 -0.15 -0.2506 -0.9846 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2048 P24 mock treatment 0.192 -0.0656 -0.94 0.237 -0.0197 -0.33 -0.897 -0.9018 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A01 compound treatment 0.248 0.0351 0.5 0.245 0.0385 0.65 0.812 0.9923 1042961 Maybridge4_000001 Clc1ccc(cc1)N2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A02 compound treatment 0.231 0.0181 0.26 0.237 0.0305 0.51 0.5451 0.9504 3062731 Maybridge4_000002 CC(=O)NS(=O)(=O)c1ccc(/N=C/c2ccco2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A03 compound treatment 0.231 0.0181 0.26 0.254 0.0475 0.8 0.7469 0.8912 3062732 Maybridge4_000003 FC(F)(F)Oc1ccc(NC(=O)Nc2ccc(cc2)C3=NCCO3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A04 compound treatment 0.253 0.0401 0.57 0.27 0.0635 1.07 1.1593 0.9579 1175682 Maybridge4_000004 COc1cccc2cc(C#N)c(=N)oc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A05 compound treatment 0.242 0.0291 0.42 0.218 0.0115 0.19 0.4309 0.9387 3062733 Maybridge4_000005 Cc1nc(ccc1C(=O)Sc2nnc(o2)c3ccc(nc3C)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A06 compound treatment 0.216 0.00312 0.04 0.247 0.0405 0.68 0.5121 0.752 3062734 Maybridge4_000006 COc1cc(/N=C/c2cccs2)c(OC)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A07 compound treatment 0.215 0.00212 0.03 0.248 0.0415 0.7 0.5138 0.7373 3062735 Maybridge4_000007 OC1CCN(CC1)C(=O)Nc2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A08 compound treatment 0.244 0.0311 0.45 0.234 0.0275 0.46 0.641 0.9998 1676427 Maybridge4_000008 Cc1ccccc1NC(=S)Nc2cc(NS(=O)(=O)C)ccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A09 compound treatment 0.216 0.00312 0.04 0.23 0.0235 0.39 0.3103 0.7823 3179439 Maybridge4_000009 Cc1nc(ccc1NC(=O)NCCNc2cccc(n2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A10 compound treatment 0.246 0.0331 0.47 0.243 0.0365 0.61 0.768 0.992 3062736 Maybridge4_000010 Cc1ccc(NC(=S)Nc2cccc(c2)C(F)(F)F)cc1NS(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A11 compound treatment 0.222 0.00912 0.13 0.223 0.0165 0.28 0.2879 0.9412 3179440 Maybridge4_000011 CC(C)(C)NC(=O)N1CCC(CC1)Nc2nccc(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A12 compound treatment 0.211 -0.00188 -0.03 0.235 0.0285 0.48 0.3191 0.6664 3062737 Maybridge4_000012 Fc1cccc(/N=C/c2ccc3OCOc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A13 compound treatment 0.243 0.0301 0.43 0.204 -0.00252 -0.04 0.2748 0.6348 3179441 Maybridge4_000013 OC(=O)c1ccccc1C(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A14 compound treatment 0.097 -0.116 -1.66 0.096 -0.111 -1.85 -2.4836 -0.9984 3062738 Maybridge4_000014 CCOC(=O)CCN1C(=O)c2ccccc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A15 compound treatment 0.162 -0.0509 -0.73 0.158 -0.0485 -0.81 -1.0904 -0.9984 1678888 Maybridge4_000015 C(Cc1ccccc1)Nc2ncnc3scc(c4ccccc4)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A16 compound treatment 0.247 0.0341 0.49 0.238 0.0315 0.53 0.7188 0.9992 1222400 Maybridge4_000016 Oc1ccc(CCc2nnc(S)n2CCc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A17 compound treatment 0.241 0.0281 0.4 0.215 0.00848 0.14 0.3851 0.9025 3179442 Maybridge4_000017 OC(=O)/C=C/C(=O)N1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A18 compound treatment 0.216 0.00312 0.04 0.225 0.0185 0.31 0.251 0.8007 3179443 Maybridge4_000018 CN(C(=O)CSc1ccc(Cl)cc1)c2ccccc2C(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A19 compound treatment 0.2 -0.0129 -0.18 0.214 0.00748 0.13 -0.0414 -0.1857 1712315 Maybridge4_000019 COc1cccc(OC)c1C(=O)N2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A20 compound treatment 0.235 0.0221 0.32 0.195 -0.0115 -0.19 0.0871 0.2349 3179444 Maybridge4_000020 CC(C)(C)NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A21 compound treatment 0.23 0.0171 0.24 0.219 0.0125 0.21 0.3214 0.997 3062739 Maybridge4_000021 NC(=O)C1CCN(CC1)c2nccc(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A22 compound treatment 0.23 0.0171 0.24 0.224 0.0175 0.29 0.3807 0.996 1149418 Maybridge4_000022 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Oc2c(C)cccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A23 mock treatment 0.217 0.00412 0.06 0.211 0.00448 0.08 0.0949 0.9928 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 A24 mock treatment 0.225 0.0121 0.17 0.218 0.0115 0.19 0.2589 0.9986 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B01 compound treatment 0.236 0.0231 0.33 0.24 0.0335 0.56 0.6313 0.9681 3062740 Maybridge4_000023 CCSC1=NCN(Cc2cccs2)CN1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B02 compound treatment 0.268 0.0551 0.79 0.23 0.0235 0.39 0.8363 0.9487 3179445 Maybridge4_000024 Cc1ccc(CNC(=O)c2cccnc2Sc3cccc(c3)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B03 compound treatment 0.191 -0.0219 -0.31 0.219 0.0125 0.21 -0.0731 -0.1941 3062741 Maybridge4_000025 CN(/N=C/c1cc(Cl)cc(Cl)c1O)C(=S)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B04 compound treatment 0.235 0.0221 0.32 0.251 0.0445 0.75 0.7517 0.927 3179446 Maybridge4_000026 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)/C=C\C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B05 compound treatment 0.262 0.0491 0.7 0.23 0.0235 0.39 0.7756 0.9626 3062742 Maybridge4_000027 Cc1c(C)c(C)c(CS(=O)(=O)CC(=O)Nc2ccc(F)c(Cl)c2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B06 compound treatment 0.262 0.0491 0.7 0.259 0.0525 0.88 1.1197 0.9937 1435448 Maybridge4_000028 Cc1onc(c1NC(=O)Oc2ccc(CC#N)cc2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B07 compound treatment 0.231 0.0181 0.26 0.247 0.0405 0.68 0.6638 0.9127 1192420 Maybridge4_000029 S=C(NCCc1ccccn1)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B08 compound treatment 0.267 0.0541 0.77 0.29 0.0835 1.4 1.5382 0.9609 1239033 Maybridge4_000030 CSc1nnc(SC)n1CCNC(=O)Nc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B09 compound treatment 0.242 0.0291 0.42 0.244 0.0375 0.63 0.7394 0.98 3179447 Maybridge4_000031 Fc1c(Br)cc(Br)c2nc(oc(=O)c12)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B10 compound treatment 0.27 0.0571 0.82 0.258 0.0515 0.86 1.1888 0.9996 3062743 Maybridge4_000032 Fc1ccc(Oc2ccc(NC(=O)/C=C/c3ccccc3)cn2)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B11 compound treatment 0.064 -0.149 -2.13 0.059 -0.148 -2.48 -3.2565 -0.9972 3179448 Maybridge4_000033 FC(F)(F)c1ccc2[nH]c(SCc3ccc(Br)cc3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B12 compound treatment 0.253 0.0401 0.57 0.245 0.0385 0.65 0.8626 0.9983 1161087 Maybridge4_000034 Fc1ccc(cc1)n2nc3NCCCn3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B13 compound treatment 0.274 0.0611 0.87 0.254 0.0475 0.8 1.1818 0.9989 3062744 Maybridge4_000035 FC(F)(F)c1cccc(c1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B14 compound treatment 0.226 0.0131 0.19 0.207 4.84E-4 0.01 0.1385 0.737 1279124 Maybridge4_000036 CCCCn1c(CSc2ccccn2)cn(c3nnc(s3)C(C)(C)C)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B15 compound treatment 0.206 -0.00688 -0.1 0.211 0.00448 0.08 -0.0163 -0.1318 1108923 Maybridge4_000037 CSC1=NC=C(C#N)C2=NC(NN21)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B16 compound treatment 0.268 0.0551 0.79 0.238 0.0315 0.53 0.9312 0.9811 1163777 Maybridge4_000038 CC(C)(C)c1cc(cc(c1)C(=O)Oc2cncc(Cl)c2)C(=O)Oc3cncc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B17 compound treatment 0.248 0.0351 0.5 0.23 0.0235 0.39 0.634 0.9928 1150645 Maybridge4_000039 Cc1cc(NS(=O)(=O)c2ccc(F)c(Cl)c2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B18 compound treatment 0.237 0.0241 0.35 0.243 0.0365 0.61 0.677 0.9632 3179449 Maybridge4_000040 CSc1ncccc1C2=N/C(=C\N(C)C)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B19 compound treatment 0.234 0.0211 0.3 0.216 0.00948 0.16 0.3262 0.9552 3062745 Maybridge4_000041 CN(C)/C=N/c1nnc(SCC(=O)c2ccc(F)cc2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B20 compound treatment 0.223 0.0101 0.14 0.213 0.00648 0.11 0.1794 0.9901 3179558 Maybridge4_000042 COC(=O)/C(=C/1\NC(=NC(=C1C#N)SC)C)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B21 compound treatment 0.258 0.0451 0.65 0.237 0.0305 0.51 0.8182 0.9934 3179559 Maybridge4_000043 CN(C)/C=N/c1nnc(Sc2cc(C)nc3ccccc23)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B22 compound treatment 0.29 0.0771 1.1 0.229 0.0225 0.38 1.0469 0.8979 3062746 Maybridge4_000044 CCOC(=O)c1c(C)c(C#N)c(/N=C/N(C)C)n1c2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B23 mock treatment 0.251 0.0381 0.55 0.21 0.00348 0.06 0.427 0.7785 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 B24 mock treatment 0.232 0.0191 0.27 0.229 0.0225 0.38 0.4603 0.9875 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C01 compound treatment 0.223 0.0101 0.14 0.248 0.0415 0.7 0.5947 0.8363 1040601 Maybridge4_000045 COc1cccc(c1)N2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C02 compound treatment 0.2 -0.0129 -0.18 0.238 0.0315 0.53 0.2434 0.435 3062747 Maybridge4_000046 COc1cc(/C=N/N)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C03 compound treatment 0.22 0.00712 0.1 0.243 0.0365 0.61 0.5051 0.8136 3179560 Maybridge4_000047 FC(F)(F)c1cccnc1N2CCNC2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C04 compound treatment 0.25 0.0371 0.53 0.218 0.0115 0.19 0.5118 0.9059 1723231 Maybridge4_000048 Clc1c(sc2ccccc12)C(=O)N(Cc3ccccc3)C(C#N)c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C05 compound treatment 0.28 0.0671 0.96 0.208 0.00148 0.02 0.6965 0.7252 3062748 Maybridge4_000049 Cc1ccc(NC(=S)N2CCCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C06 compound treatment 0.262 0.0491 0.7 0.236 0.0295 0.49 0.8468 0.9853 1322626 Maybridge4_000050 Fc1ccc(cc1)N(Cc2ccc3OCOc3c2)S(=O)(=O)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C07 compound treatment 0.197 -0.0159 -0.23 0.194 -0.0125 -0.21 -0.3091 -0.9992 1288233 Maybridge4_000051 CCOC(=O)c1cc(C(=O)OC)c(C)nc1N2CCCN(Cc3ccc(F)cc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C08 compound treatment 0.218 0.00512 0.07 0.245 0.0385 0.65 0.5086 0.7823 3179561 Maybridge4_000052 CCOC(=O)/C(=C(/C)\N)/C1CC(=O)N(C1=O)c2ccc(cc2)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C09 compound treatment 0.208 -0.00488 -0.07 0.181 -0.0255 -0.43 -0.3521 -0.8116 1354107 Maybridge4_000053 OC(COc1ccc(Br)cc1)CN2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C10 compound treatment 0.2 -0.0129 -0.18 0.259 0.0525 0.88 0.4927 0.5474 1692586 Maybridge4_000054 Cc1ccc(cc1)S(=O)(=O)N(c2nc3ccccc3s2)c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C11 compound treatment 0.24 0.0271 0.39 0.248 0.0415 0.7 0.7667 0.9619 1369581 Maybridge4_000055 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)Nc2ccc(F)cc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C12 compound treatment 0.246 0.0331 0.47 0.242 0.0355 0.6 0.7562 0.9936 1212228 Maybridge4_000056 Cc1ccc(c(NC(=O)C(C2CCCC2)c3ccccc3)c1)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C13 compound treatment 0.245 0.0321 0.46 0.199 -0.00752 -0.13 0.2357 0.4947 3179562 Maybridge4_000057 Cc1nc(ccc1C(=O)NCC2CC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C14 compound treatment 0.041 -0.172 -2.46 0.189 -0.0175 -0.29 -1.9463 -0.7861 1629863 Maybridge4_000058 Oc1c(Cl)cc(Cl)cc1C2Nc3cccc4cccc(N2)c34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C15 compound treatment 0.281 0.0681 0.97 0.252 0.0455 0.76 1.2288 0.9927 3062749 Maybridge4_000059 CCCNC(=O)NC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C16 compound treatment 0.201 -0.0119 -0.17 0.04 -0.167 -2.79 -2.0963 -0.7487 1569566 Maybridge4_000060 CC(c1ccccc1)n2c(S)nnc2CCc3ccc(O)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C17 compound treatment 0.217 0.00412 0.06 0.212 0.00548 0.09 0.1068 0.9769 1204274 Maybridge4_000061 Fc1cccc(Cl)c1CN2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C18 compound treatment 0.04 -0.173 -2.47 0.179 -0.0275 -0.46 -2.0751 -0.8249 1455358 Maybridge4_000062 O=C(Nc1nccc2ccccc12)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C19 compound treatment 0.052 -0.161 -2.3 0.208 0.00148 0.02 -1.6095 -0.6994 3179563 Maybridge4_000063 COc1cccc(CC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C20 compound treatment 0.041 -0.172 -2.46 0.214 0.00748 0.13 -1.6496 -0.6701 3062750 Maybridge4_000064 CC(C)(C)NC(=S)Nc1ccccc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C21 compound treatment 0.257 0.0441 0.63 0.224 0.0175 0.29 0.6538 0.9393 1137780 Maybridge4_000065 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2ccc(Oc3cccnc3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C22 compound treatment 0.196 -0.0169 -0.24 0.197 -0.00952 -0.16 -0.2836 -0.9799 3179564 Maybridge4_000066 FC(F)(F)c1cc(NCC(=O)c2cc3cc(Cl)ccc3o2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C23 mock treatment 0.183 -0.0299 -0.43 0.196 -0.0105 -0.18 -0.427 -0.9235 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 C24 mock treatment 0.225 0.0121 0.17 0.181 -0.0255 -0.43 -0.1802 -0.39 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D01 compound treatment 0.262 0.0491 0.7 0.225 0.0185 0.31 0.7162 0.9325 3179565 Maybridge4_000067 Cc1nn(nc1C(=O)Oc2c(Cl)cccc2Cl)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D02 compound treatment 0.205 -0.00788 -0.11 0.227 0.0205 0.34 0.1635 0.4518 3062751 Maybridge4_000068 COc1cc(cc(Br)c1OC(=O)NC(=O)c2c(F)cccc2F)C3SCCS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D03 compound treatment 0.256 0.0431 0.62 0.227 0.0205 0.34 0.6793 0.9619 1545199 Maybridge4_000069 CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1N3CC(C)OC(C)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D04 compound treatment 0.252 0.0391 0.56 0.237 0.0305 0.51 0.7575 0.999 1652603 Maybridge4_000070 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)CCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D05 compound treatment 0.246 0.0331 0.47 0.263 0.0565 0.95 1.0054 0.9486 1338281 Maybridge4_000071 Clc1ccccc1C(=O)NC(=O)NC2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D06 compound treatment 0.268 0.0551 0.79 0.239 0.0325 0.55 0.9431 0.9838 1457562 Maybridge4_000072 OC(=O)C(CCC(=O)Nc1ccc2OCOCc2c1)N3C(=O)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D07 compound treatment 0.224 0.0111 0.16 0.223 0.0165 0.28 0.3082 0.9655 3062752 Maybridge4_000073 CC1CN(CC(C)O1)C2=NCCN2S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D08 compound treatment 0.256 0.0431 0.62 0.249 0.0425 0.71 0.9404 0.9974 3179566 Maybridge4_000074 Cc1nn(nc1C(=O)c2c(O)n(nc2C(C)(C)C)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D09 compound treatment 0.237 0.0241 0.35 0.269 0.0625 1.05 0.9856 0.8927 3062753 Maybridge4_000075 Cc1cc(Br)c(c(Br)c1Cl)n2cccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D10 compound treatment 0.196 -0.0169 -0.24 0.232 0.0255 0.43 0.1318 0.2683 3179567 Maybridge4_000076 Fc1ccc(Oc2ncccc2NC(=O)/C=C/c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D11 compound treatment 0.277 0.0641 0.92 0.275 0.0685 1.15 1.4613 0.9937 3062754 Maybridge4_000077 CC(C)(C)c1cs/c(=N/c2ccccn2)/n1c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D12 compound treatment 0.249 0.0361 0.52 0.216 0.00948 0.16 0.4779 0.8839 1415138 Maybridge4_000078 CN1C(C(=O)N(C1=O)c2nnc(s2)C(C)(C)C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D13 compound treatment 0.263 0.0501 0.72 0.23 0.0235 0.39 0.7857 0.9603 3063175 Maybridge4_000079 CC(C)(C)c1csc(Cc2ccccc2Cl)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D14 compound treatment 0.26 0.0471 0.67 0.21 0.00348 0.06 0.518 0.7656 3179568 Maybridge4_000080 Fc1ccc(NC(=O)CSc2nnc(NC(=O)c3ccc(Cl)c(Cl)c3)s2)c(F)c1F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D15 compound treatment 0.308 0.0951 1.36 0.299 0.0925 1.55 2.0597 0.9978 1691601 Maybridge4_000081 CS(=O)(=O)Nc1ccc2oc3ncccc3c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D16 compound treatment 0.264 0.0511 0.73 0.254 0.0475 0.8 1.0806 0.9991 1489888 Maybridge4_000082 CC(C)(C)c1cc(cc(c1)C(=O)NCc2cccs2)C(=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D17 compound treatment 0.216 0.00312 0.04 0.219 0.0125 0.21 0.1798 0.8391 3063176 Maybridge4_000083 Clc1ccc(cc1Cl)C(=O)c2nn3c(nc(=O)c4ccccc43)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D18 compound treatment 0.284 0.0711 1.02 0.269 0.0625 1.05 1.4609 0.9999 3179569 Maybridge4_000084 CN(C)/C=C/1\N=C(OC1=O)c2cccnc2Oc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D19 compound treatment 0.201 -0.0119 -0.17 0.228 0.0215 0.36 0.1349 0.3384 1342823 Maybridge4_000085 Fc1ccc(c(F)c1)S(=O)(=O)Nc2ccccc2C(=O)NCC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D20 compound treatment 0.243 0.0301 0.43 0.26 0.0535 0.9 0.9394 0.9435 3063177 Maybridge4_000086 CC(C)(C(=O)Nc1cccc(Cl)c1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D21 compound treatment 0.285 0.0721 1.03 0.276 0.0695 1.17 1.5541 0.9981 3063178 Maybridge4_000087 CC1=NN(C(=O)CC1)c2cc(Cl)cc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D22 compound treatment 0.191 -0.0219 -0.31 0.155 -0.0515 -0.86 -0.8326 -0.9055 1609394 Maybridge4_000088 CCOC(=O)c1c(C)c(C#N)c(N(C(=O)C)C(=O)C)n1c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D23 mock treatment 0.251 0.0381 0.55 0.209 0.00248 0.04 0.4151 0.7589 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 D24 mock treatment 0.186 -0.0269 -0.38 0.22 0.0135 0.23 -0.1118 -0.2506 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E01 compound treatment 0.217 0.00412 0.06 0.25 0.0435 0.73 0.5578 0.7618 1042964 Maybridge4_000089 Cc1cccc(c1)N2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E02 compound treatment 0.226 0.0131 0.19 0.244 0.0375 0.63 0.5776 0.8798 1679137 Maybridge4_000090 NNC(=O)C1CCCNC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E03 compound treatment 0.242 0.0291 0.42 0.196 -0.0105 -0.18 0.1698 0.3752 1296373 Maybridge4_000091 CC(C)(C)OC(=O)N1CCCN(CC1)S(=O)(=O)c2cc(Cl)ccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E04 compound treatment 0.204 -0.00888 -0.13 0.205 -0.00152 -0.03 -0.1078 -0.8323 1584716 Maybridge4_000092 COc1cc(cc(OC)c1OC)C(=O)NC(=S)NC(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E05 compound treatment 0.222 0.00912 0.13 0.228 0.0215 0.36 0.3473 0.9056 3063179 Maybridge4_000093 CSc1nnc(o1)c2ccc(nc2C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E06 compound treatment 0.272 0.0591 0.85 0.225 0.0185 0.31 0.8174 0.9074 3179570 Maybridge4_000094 Cc1onc(c1C(=O)NC(=S)Nc2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E07 compound treatment 0.308 0.0951 1.36 0.296 0.0895 1.5 2.0241 0.9988 1200576 Maybridge4_000095 CCOC(=O)c1cc(C(=O)OC)c(C)nc1SCC(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E08 compound treatment 0.225 0.0121 0.17 0.272 0.0655 1.1 0.8998 0.8087 1402318 Maybridge4_000096 CCOC(=O)C1=C(C)NC(=O)C1CC(=O)Nc2ccc(cc2)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E09 compound treatment 0.279 0.0661 0.95 0.296 0.0895 1.5 1.7308 0.9752 1736057 Maybridge4_000097 CCOC(=O)c1cc(C#N)c(C)nc1N2CCN(CC2)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E10 compound treatment 0.251 0.0381 0.55 0.205 -0.00152 -0.03 0.3676 0.6734 1619754 Maybridge4_000098 CC(=O)Nc1ccc(C)c(NC(=S)Nc2ccc(Cl)c(Cl)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E11 compound treatment 0.254 0.0411 0.59 0.24 0.0335 0.56 0.8133 0.9997 1175297 Maybridge4_000099 O=C1CC2(CCCC2)C(=O)N1CCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E12 compound treatment 0.246 0.0331 0.47 0.228 0.0215 0.36 0.59 0.9909 3179665 Maybridge4_000100 COc1cc(NC(=O)C(C2CCCC2)c3ccccc3)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E13 compound treatment 0.236 0.0231 0.33 0.238 0.0315 0.53 0.6075 0.9745 1528875 Maybridge4_000101 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(s3)c4csc(C)n4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E14 compound treatment 0.238 0.0251 0.36 0.25 0.0435 0.73 0.7702 0.9467 1511104 Maybridge4_000102 CN(C)c1ccc(cc1)C2N(Cc3ccccc3)CCC4CCCCN24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E15 compound treatment 0.26 0.0471 0.67 0.202 -0.00452 -0.08 0.423 0.6237 3063180 Maybridge4_000103 FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E16 compound treatment 0.164 -0.0489 -0.7 0.251 0.0445 0.75 0.0336 0.0329 3179666 Maybridge4_000104 C/C(=N\C(=O)NN)/c1cnn(c1C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E17 compound treatment 0.207 -0.00588 -0.08 0.201 -0.00552 -0.09 -0.1249 -0.9988 3179667 Maybridge4_000105 C(CNc1ncnc2scc(c3ccccc3)c12)Cn4ccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E18 compound treatment 0.25 0.0371 0.53 0.231 0.0245 0.41 0.6661 0.992 1369305 Maybridge4_000106 CCN1CCCC1CN2CNC(=S)NC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E19 compound treatment 0.207 -0.00588 -0.08 0.199 -0.00752 -0.13 -0.1486 -0.9805 3179668 Maybridge4_000107 FC(F)(F)c1ccnc(n1)N2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E20 compound treatment 0.192 -0.0209 -0.3 0.267 0.0605 1.02 0.5067 0.4788 3063181 Maybridge4_000108 CSc1cccc(NC(=S)NC(C)(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E21 compound treatment 0.193 -0.0199 -0.28 0.162 -0.0445 -0.75 -0.7293 -0.9123 1338166 Maybridge4_000109 Cc1cnc(N2CCN(CC2)NC(=S)Nc3cccnc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E22 compound treatment 0.214 0.00112 0.02 0.186 -0.0205 -0.34 -0.2321 -0.6733 1138152 Maybridge4_000110 COc1ccc(NC(=S)NC(C)(C)C)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E23 mock treatment 0.203 -0.00987 -0.14 0.212 0.00548 0.09 -0.0348 -0.2064 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 E24 mock treatment 0.221 0.00812 0.12 0.218 0.0115 0.19 0.2185 0.9707 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F01 compound treatment 0.22 0.00712 0.1 0.234 0.0275 0.46 0.3982 0.843 1442676 Maybridge4_000111 Fc1cccc(Cl)c1C(=O)NC(=O)N2CCSC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F02 compound treatment 0.26 0.0471 0.67 0.23 0.0235 0.39 0.7553 0.9673 3179669 Maybridge4_000112 CN(C)/C(=N/c1nnc(Sc2nc3cc(Cl)ccc3s2)s1)/C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F03 compound treatment 0.217 0.00412 0.06 0.197 -0.00952 -0.16 -0.0712 -0.4183 3179670 Maybridge4_000113 Fc1ccc(NC(=O)NCSCc2cccc(c2)C(F)(F)F)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F04 compound treatment 0.253 0.0401 0.57 0.225 0.0185 0.31 0.6252 0.9583 1189445 Maybridge4_000114 COc1cccc(c1)c2nnc(o2)c3ccccc3NS(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F05 compound treatment 0.256 0.0431 0.62 0.249 0.0425 0.71 0.9404 0.9974 3179671 Maybridge4_000115 FC(F)(F)c1cccc(c1)C(=O)NC2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F06 compound treatment 0.258 0.0451 0.65 0.234 0.0275 0.46 0.7826 0.9864 1529642 Maybridge4_000116 Cc1cc2ncc(nc2cc1C)c3ccn(c3)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F07 compound treatment 0.29 0.0771 1.1 0.281 0.0745 1.25 1.664 0.9981 1440337 Maybridge4_000117 Clc1cccc(Cl)c1C(=O)NC2CCS(=O)(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F08 compound treatment 0.276 0.0631 0.9 0.295 0.0885 1.49 1.6886 0.9715 1688196 Maybridge4_000118 COc1ccc(Cl)c(OC)c1C(=O)NC(=O)Nc2c(C)cccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F09 compound treatment 0.217 0.00412 0.06 0.196 -0.0105 -0.18 -0.0831 -0.4464 3063182 Maybridge4_000119 COC(=O)/C=C/1\S/C(=N\c2ccc(C)c(C)c2)/N(C1=O)c3ccc(C)c(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F10 compound treatment 0.31 0.0971 1.39 0.269 0.0625 1.05 1.7239 0.9904 3179672 Maybridge4_000120 NNC(=O)CS(=O)(=O)c1ccc(cn1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F11 compound treatment 0.25 0.0371 0.53 0.304 0.0975 1.64 1.5324 0.8909 3179673 Maybridge4_000121 Cc1ncc(CSc2nc3cc(ccc3[nH]2)C(F)(F)F)c(CO)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F12 compound treatment 0.297 0.0841 1.2 0.308 0.101 1.7 2.0553 0.9855 1621608 Maybridge4_000122 Cc1cc(cc(C)c1O)c2nn(C)c(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F13 compound treatment 0.351 0.138 1.98 0.351 0.144 2.43 3.1118 0.9948 1331054 Maybridge4_000123 CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)c2c(F)cccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F14 compound treatment 0.047 -0.166 -2.37 0.043 -0.164 -2.74 -3.6183 -0.9974 3063183 Maybridge4_000124 FC(F)(F)c1nnc(NC(=O)Nc2ccccc2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F15 compound treatment 0.316 0.103 1.48 0.32 0.113 1.9 2.3899 0.992 3179674 Maybridge4_000125 COc1cc2c(=O)oc(nc2c(OC)c1OC)c3c(C)onc3c4c(F)cccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F16 compound treatment 0.282 0.0691 0.99 0.283 0.0765 1.28 1.6069 0.9917 3063184 Maybridge4_000126 Brc1ccc(s1)c2cnc3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F17 compound treatment 0.271 0.0581 0.83 0.278 0.0715 1.2 1.4363 0.9839 1216365 Maybridge4_000127 Clc1ccc(Oc2nc(Oc3ccc(Cl)cc3)nc(n2)N4CCSCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F18 compound treatment 0.267 0.0541 0.77 0.321 0.114 1.92 1.9061 0.9201 1464435 Maybridge4_000128 CC(C)(C)c1ccc(Oc2ncccc2C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F19 compound treatment 0.273 0.0601 0.86 0.282 0.0755 1.27 1.504 0.9822 1281583 Maybridge4_000129 Cc1nn(nc1C(=O)NC(=O)N2CCSCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F20 compound treatment 0.224 0.0111 0.16 0.257 0.0505 0.85 0.7117 0.8255 3063185 Maybridge4_000130 CC(C)(C(=O)Oc1ccccc1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F21 compound treatment 0.251 0.0381 0.55 0.264 0.0575 0.96 1.0678 0.9635 3179675 Maybridge4_000131 CC(C)(C)SCCNc1nc(Sc2ccc(Cl)cc2)nc(n1)N3CCSCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F22 compound treatment 0.231 0.0181 0.26 0.19 -0.0165 -0.28 -0.0127 -0.0334 3063186 Maybridge4_000132 CSc1nn(C)c2cnn(C)c(=O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F23 mock treatment 0.255 0.0421 0.6 0.249 0.0425 0.71 0.9303 0.9965 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 F24 mock treatment 0.19 -0.0229 -0.33 0.211 0.00448 0.08 -0.1781 -0.5306 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G01 compound treatment 0.245 0.0321 0.46 0.23 0.0235 0.39 0.6036 0.9971 3063187 Maybridge4_000133 Cc1ccccc1N2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G02 compound treatment 0.213 1.25E-4 0.0 0.204 -0.00252 -0.04 -0.0286 -0.6766 3179676 Maybridge4_000134 c1ccc(nc1)c2nnc([nH]2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G03 compound treatment 0.219 0.00612 0.09 0.201 -0.00552 -0.09 -0.0035 -0.0276 1229940 Maybridge4_000135 OC(CNCc1ccc(Cl)cc1Cl)Cn2c(cc3ccccc23)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G04 compound treatment 0.206 -0.00688 -0.1 0.241 0.0345 0.58 0.3397 0.5787 3063224 Maybridge4_000136 NC(=O)NC(=S)NC(=O)c1ccccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G05 compound treatment 0.223 0.0101 0.14 0.244 0.0375 0.63 0.5473 0.8477 3063225 Maybridge4_000137 FC(F)(F)c1cccc(NC(=S)NCCNc2nccc(n2)C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G06 compound treatment 0.246 0.0331 0.47 0.282 0.0755 1.27 1.2309 0.91 1407734 Maybridge4_000138 Cc1cccc(C)c1NC(=S)N2CCCc3cccc(C)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G07 compound treatment 0.332 0.119 1.7 0.3 0.0935 1.57 2.3143 0.9992 3063226 Maybridge4_000139 Cc1nc(ccc1C(=O)O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G08 compound treatment 0.231 0.0181 0.26 0.265 0.0585 0.98 0.8774 0.8642 3063227 Maybridge4_000140 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G09 compound treatment 0.257 0.0441 0.63 0.251 0.0445 0.75 0.9742 0.9965 1525364 Maybridge4_000141 COc1ccccc1NC(=O)N2CCCN(Cc3ccc(F)cc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G10 compound treatment 0.291 0.0781 1.12 0.283 0.0765 1.28 1.6979 0.9976 3179677 Maybridge4_000142 Cc1cccc2c(=O)n(CCNCc3ccccc3)c(C)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G11 compound treatment 0.275 0.0621 0.89 0.302 0.0955 1.6 1.7616 0.9613 1397176 Maybridge4_000143 Cc1cc(c(C)cc1Cl)S(=O)(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G12 compound treatment 0.318 0.105 1.5 0.269 0.0625 1.05 1.8048 0.9845 1223333 Maybridge4_000144 COc1cc2CCN=C(c3c(C)onc3c4ccccc4)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G13 compound treatment 0.244 0.0311 0.45 0.245 0.0385 0.65 0.7715 0.9835 3179678 Maybridge4_000145 Clc1ccc(cc1)S(=O)(=O)NCCNc2ncnc3scc(c4ccccc4)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G14 compound treatment 0.281 0.0681 0.97 0.242 0.0355 0.6 1.1102 0.9721 3063228 Maybridge4_000146 FC(F)(F)c1cc(NC(=O)CSC(=O)c2ccco2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G15 compound treatment 0.298 0.0851 1.22 0.277 0.0705 1.18 1.6975 0.9999 1479980 Maybridge4_000147 COc1cccc(OC)c1C(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G16 compound treatment 0.251 0.0381 0.55 0.22 0.0135 0.23 0.5456 0.9241 3063229 Maybridge4_000148 FC(F)(F)c1cccc(c1)N2CCNC2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G17 compound treatment 0.21 -0.00288 -0.04 0.293 0.0865 1.45 0.9973 0.6868 1615569 Maybridge4_000149 Ic1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G18 compound treatment 0.166 -0.0469 -0.67 0.231 0.0245 0.41 -0.1835 -0.2334 3063230 Maybridge4_000150 FC(F)(F)c1cc(Br)ccc1/N=C/c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G19 compound treatment 0.207 -0.00588 -0.08 0.256 0.0495 0.83 0.5279 0.6323 3179679 Maybridge4_000151 Fc1cccc(Cl)c1CN2CCN(CCCNC(=O)c3cccc(c3)C(F)(F)F)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G20 compound treatment 0.153 -0.0599 -0.86 0.158 -0.0485 -0.81 -1.1814 -0.9997 3063231 Maybridge4_000152 Cc1ccc(NC(=S)NC(C)(C)C)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G21 compound treatment 0.151 -0.0619 -0.89 0.138 -0.0685 -1.15 -1.439 -0.9916 3179680 Maybridge4_000153 CSc1cccc(NC(=O)/C=C/c2ccc(cc2)C(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G22 compound treatment 0.211 -0.00188 -0.03 0.205 -0.00152 -0.03 -0.037 -0.9997 3063232 Maybridge4_000154 S=C1NCN(Cc2cccs2)CN1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G23 mock treatment 0.214 0.00112 0.02 0.198 -0.00852 -0.14 -0.0897 -0.6236 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 G24 mock treatment 0.205 -0.00788 -0.11 0.155 -0.0515 -0.86 -0.691 -0.7925 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H01 compound treatment 0.221 0.00812 0.12 0.244 0.0375 0.63 0.527 0.8238 3179681 Maybridge4_000155 Cc1ccc(SCc2ccccc2c3nc4ccccc4[nH]3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H02 compound treatment 0.27 0.0571 0.82 0.231 0.0245 0.41 0.8684 0.9494 3063233 Maybridge4_000156 CN(C)/C=N/c1nnc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H03 compound treatment 0.258 0.0451 0.65 0.229 0.0225 0.38 0.7232 0.9673 3179769 Maybridge4_000157 CCC(C)n1c(=O)[nH][nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H04 compound treatment 0.242 0.0291 0.42 0.237 0.0305 0.51 0.6564 0.9948 1039773 Maybridge4_000158 Cc1ccc(=O)n(Cc2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H05 compound treatment 0.266 0.0531 0.76 0.218 0.0115 0.19 0.6736 0.8593 3179770 Maybridge4_000159 Fc1cccc(CSC2=NCN(CN2)C3CC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H06 compound treatment 0.26 0.0471 0.67 0.235 0.0285 0.48 0.8147 0.9858 3063234 Maybridge4_000160 FC(F)(F)c1cc(COc2ccc(CC#N)cc2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H07 compound treatment 0.287 0.0741 1.06 0.233 0.0265 0.44 1.064 0.9255 1661120 Maybridge4_000161 COc1ccc(OC)c(c1)S(=O)(=O)NC2CCS(=O)(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H08 compound treatment 0.224 0.0111 0.16 0.274 0.0675 1.13 0.9134 0.7986 3063235 Maybridge4_000162 CN(C)/C=N/c1ccc(Oc2cncc(Cl)c2)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H09 compound treatment 0.174 -0.0389 -0.56 0.169 -0.0375 -0.63 -0.8384 -0.9981 3179771 Maybridge4_000163 Fc1ccc2sc(NC(=O)NC(=O)c3c(Cl)cccc3Cl)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H10 compound treatment 0.301 0.0881 1.26 0.303 0.0965 1.62 2.0364 0.9923 3063236 Maybridge4_000164 CC(=C)C(=O)Nc1ccc(Oc2ccccc2F)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H11 compound treatment 0.307 0.0941 1.35 0.269 0.0625 1.05 1.6936 0.9924 3179772 Maybridge4_000165 Cc1cc(ccc1Cl)C2(O)CSc3nc4cc(ccc4n32)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H12 compound treatment 0.269 0.0561 0.8 0.283 0.0765 1.28 1.4754 0.9745 1316383 Maybridge4_000166 Cc1ccc(cc1)C(=O)Oc2c(C)cc(cc2C)c3nn(C)c(=O)c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H13 compound treatment 0.231 0.0181 0.26 0.27 0.0635 1.07 0.9368 0.8542 1008407 Maybridge4_000167 Clc1ccc(OCOc2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H14 compound treatment 0.31 0.0971 1.39 0.26 0.0535 0.9 1.6171 0.9777 3179773 Maybridge4_000168 CN(C)/C=C(\Sc1nnc(N)s1)/C(=O)Nc2ccc(F)c(F)c2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H15 compound treatment 0.3 0.0871 1.25 0.317 0.11 1.85 2.1924 0.9813 3063237 Maybridge4_000169 O=c1ncn(Cc2cccs2)cc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H16 compound treatment 0.271 0.0581 0.83 0.29 0.0835 1.4 1.5787 0.9689 1639465 Maybridge4_000170 COC(=O)CNC(=O)c1cccnc1Sc2cc(OC)ccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H17 compound treatment 0.235 0.0221 0.32 0.258 0.0515 0.86 0.8348 0.9072 3063238 Maybridge4_000171 CCOC(=O)c1cc(CC)sc1NC(=S)Nc2ccccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H18 compound treatment 0.24 0.0271 0.39 0.298 0.0915 1.54 1.3601 0.8588 1639248 Maybridge4_000172 CN(N1CC(C)(C)C1=O)c2cnn(c3ccc(C)cc3)c(=O)c2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H19 compound treatment 0.236 0.0231 0.33 0.243 0.0365 0.61 0.6669 0.9582 1494290 Maybridge4_000173 CC1CN(CC(C)O1)C(=O)NC(=O)c2nn(nc2C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H20 compound treatment 0.248 0.0351 0.5 0.242 0.0355 0.6 0.7764 0.9964 3179774 Maybridge4_000174 Cc1ccc(/C=C/c2onc3c(=O)[nH]nc(C)c23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H21 compound treatment 0.258 0.0451 0.65 0.239 0.0325 0.55 0.8419 0.9965 3179775 Maybridge4_000175 Cc1cc(=O)oc2[nH]nc(CSc3ccc(Cl)cc3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H22 compound treatment 0.199 -0.0139 -0.2 0.187 -0.0195 -0.33 -0.372 -0.9712 1137912 Maybridge4_000176 CCOC(=O)c1c(C)c(C#N)c(NC(=O)c2ccc(Cl)cc2Cl)n1c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H23 mock treatment 0.206 -0.00688 -0.1 0.227 0.0205 0.34 0.1736 0.4854 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 H24 mock treatment 0.208 -0.00488 -0.07 0.182 -0.0245 -0.41 -0.3403 -0.8153 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I01 compound treatment 0.202 -0.0109 -0.16 0.256 0.0495 0.83 0.4773 0.5649 3179776 Maybridge4_000177 OC(=O)C1CCc2ccccc2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I02 compound treatment 0.203 -0.00987 -0.14 0.237 0.0305 0.51 0.2619 0.4934 1265650 Maybridge4_000178 OC(=O)c1ccccc1NC(=O)c2ccccc2NC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I03 compound treatment 0.223 0.0101 0.14 0.264 0.0575 0.96 0.7846 0.8042 3063239 Maybridge4_000179 COc1ccc(CC/N=C/c2ccc(Oc3nccc(n3)C(F)(F)F)cc2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I04 compound treatment 0.238 0.0251 0.36 0.237 0.0305 0.51 0.6159 0.9851 3179777 Maybridge4_000180 Cc1ccc(Nc2nc3ccccc3s2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I05 compound treatment 0.245 0.0321 0.46 0.281 0.0745 1.25 1.2089 0.9076 3179778 Maybridge4_000181 FC(F)(F)c1ccnc(NCCNC(=S)NCc2ccco2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I06 compound treatment 0.24 0.0271 0.39 0.234 0.0275 0.46 0.6005 0.9963 3063240 Maybridge4_000182 Cc1ccc2N(CCCc2c1)C(=S)Nc3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I07 compound treatment 0.278 0.0651 0.93 0.264 0.0575 0.96 1.3409 0.9998 3179779 Maybridge4_000183 Cc1ccc(cc1)S(=O)(=O)NCCNc2nccc(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I08 compound treatment 0.267 0.0541 0.77 0.274 0.0675 1.13 1.3483 0.9828 3063241 Maybridge4_000184 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3[nH]nnc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I09 compound treatment 0.24 0.0271 0.39 0.273 0.0665 1.12 1.0634 0.9001 3179780 Maybridge4_000185 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)Nc3nccc(n3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I10 compound treatment 0.278 0.0651 0.93 0.227 0.0205 0.34 0.9018 0.9082 3063242 Maybridge4_000186 Clc1ccc2scc(/C(=C/c3cccs3)/C#N)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I11 compound treatment 0.061 -0.152 -2.17 0.069 -0.138 -2.31 -3.1682 -0.9995 3179781 Maybridge4_000187 CCOC(=O)c1c(sc(C)c1c2ccccc2)N3C(=O)C=CC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I12 compound treatment 0.302 0.0891 1.27 0.303 0.0965 1.62 2.0465 0.993 3063243 Maybridge4_000188 FC(F)(F)c1cc(NC=C2C(=O)NC(=S)NC2=O)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I13 compound treatment 0.207 -0.00588 -0.08 0.224 0.0175 0.29 0.1481 0.4851 3179782 Maybridge4_000189 Cc1nc(ccc1c2nnc(SCCCN3C(=O)c4ccccc4C3=O)o2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I14 compound treatment 0.28 0.0671 0.96 0.259 0.0525 0.88 1.3018 0.9991 3179783 Maybridge4_000190 Cc1nc2ccc(Br)cc2c(=O)n1c3cc(ccc3N4CCOCC4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I15 compound treatment 0.258 0.0451 0.65 0.229 0.0225 0.38 0.7232 0.9673 1704168 Maybridge4_000191 CC1(C)C2CCC1(CS(=O)(=O)N3CCCN(CC3)c4nc5ccc(Cl)cc5s4)C(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I16 compound treatment 0.243 0.0301 0.43 0.238 0.0315 0.53 0.6783 0.9949 3179784 Maybridge4_000192 COc1ccccc1NC(=O)CSc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I17 compound treatment 0.274 0.0611 0.87 0.254 0.0475 0.8 1.1818 0.9989 1335897 Maybridge4_000193 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)N4CCc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I18 compound treatment 0.223 0.0101 0.14 0.272 0.0655 1.1 0.8796 0.7934 3063244 Maybridge4_000194 Cc1cccc(C)c1NC(=O)CSC(=O)c2sc3ccccc3c2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I19 compound treatment 0.191 -0.0219 -0.31 0.26 0.0535 0.9 0.4135 0.435 3179785 Maybridge4_000195 FC(F)(F)c1cc(Cl)c2nc(cn2c1)C(=O)NCCCN3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I20 compound treatment 0.22 0.00712 0.1 0.238 0.0315 0.53 0.4457 0.8282 3063245 Maybridge4_000196 Cc1ccc2ncc(nc2c1)c3ccc(Cl)c(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I21 compound treatment 0.214 0.00112 0.02 0.219 0.0125 0.21 0.1595 0.7592 3063246 Maybridge4_000197 CN(C)/N=C(\C)/c1cc(Cl)cc(Cl)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I22 compound treatment 0.196 -0.0169 -0.24 0.201 -0.00552 -0.09 -0.2361 -0.9134 3179786 Maybridge4_000198 Cc1nc2c(Br)cc(Br)cc2c(=O)n1Cc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I23 mock treatment 0.211 -0.00188 -0.03 0.161 -0.0455 -0.76 -0.5592 -0.7315 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 I24 mock treatment 0.164 -0.0489 -0.7 0.195 -0.0115 -0.19 -0.631 -0.87 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J01 compound treatment 0.22 0.00712 0.1 0.215 0.00848 0.14 0.1728 0.9865 3063247 Maybridge4_000199 CSC1=NCCCN1C(=O)c2c(C)onc2c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J02 compound treatment 0.232 0.0191 0.27 0.237 0.0305 0.51 0.5552 0.957 3179787 Maybridge4_000200 FC(F)(F)C1=NN(C(=O)C1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J03 compound treatment 0.218 0.00512 0.07 0.232 0.0255 0.43 0.3543 0.8164 3063248 Maybridge4_000201 Cc1cc(ccc1Cl)C2=Nc3ccccc3SC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J04 compound treatment 0.238 0.0251 0.36 0.241 0.0345 0.58 0.6634 0.9737 3179788 Maybridge4_000202 Cc1ccc(=O)n(n1)S(=O)(=O)c2ccc(F)cc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J05 compound treatment 0.268 0.0551 0.79 0.251 0.0445 0.75 1.0855 0.9996 3063249 Maybridge4_000203 CC(C)(C)NC(=S)NC1CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J06 compound treatment 0.263 0.0501 0.72 0.264 0.0575 0.96 1.1892 0.9893 1412882 Maybridge4_000204 CN(NS(=O)(=O)c1ccc(Cl)cc1)c2cnn(C)c(=O)c2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J07 compound treatment 0.278 0.0651 0.93 0.284 0.0775 1.3 1.5783 0.9866 3179789 Maybridge4_000205 CC1CN(CC(C)O1)C2=NCCN2S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J08 compound treatment 0.253 0.0401 0.57 0.254 0.0475 0.8 0.9694 0.987 3063250 Maybridge4_000206 COC(=O)c1cc(OC(=O)c2nn(nc2C)c3ccccc3)n(n1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J09 compound treatment 0.267 0.0541 0.77 0.267 0.0605 1.02 1.2653 0.9911 3179790 Maybridge4_000207 FC(F)(F)c1ccc(OC(=O)NC(=O)c2c(Cl)cccc2Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J10 compound treatment 0.253 0.0401 0.57 0.247 0.0405 0.68 0.8863 0.9965 1174991 Maybridge4_000208 Clc1ccc(NC(=O)N2CCC(CC2)C(c3ccccc3)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J11 compound treatment 0.307 0.0941 1.35 0.321 0.114 1.92 2.3107 0.9849 1235401 Maybridge4_000209 Cc1cc(Oc2ccnc3cc(Cl)ccc23)ccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J12 compound treatment 0.292 0.0791 1.13 0.297 0.0905 1.52 1.8742 0.9895 1558885 Maybridge4_000210 Cc1cc(cc(C)c1OC(=O)Nc2ccc(Cl)cc2)c3nn(C)c(=O)c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J13 compound treatment 0.2 -0.0129 -0.18 0.233 0.0265 0.44 0.1841 0.3826 1586134 Maybridge4_000211 Clc1cccc(Cl)c1C(=O)NC(=O)N(Cc2ccccc2)C3CC4CCC3C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J14 compound treatment 0.23 0.0171 0.24 0.293 0.0865 1.45 1.1996 0.8149 3178204 Maybridge4_000212 CN(C)/C=C(\C(=O)Nc1ccc(F)c(F)c1F)/S(=O)(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J15 compound treatment 0.272 0.0591 0.85 0.236 0.0295 0.49 0.9479 0.9674 1175614 Maybridge4_000213 O=c1ncn(Cc2ccccn2)cc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J16 compound treatment 0.251 0.0381 0.55 0.244 0.0375 0.63 0.8305 0.9975 1210252 Maybridge4_000214 Cc1ccc(cc1)C(=O)COc2cc(C)nc3nncn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J17 compound treatment 0.276 0.0631 0.9 0.263 0.0565 0.95 1.3088 0.9997 1235603 Maybridge4_000215 Fc1ccc(NC(=O)Cc2nn[nH]n2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J18 compound treatment 0.243 0.0301 0.43 0.249 0.0425 0.71 0.8089 0.9709 1578276 Maybridge4_000216 CN(c1cnn(c2ccc(C)cc2)c(=O)c1Cl)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J19 compound treatment 0.239 0.0261 0.37 0.275 0.0685 1.15 1.077 0.8911 1321013 Maybridge4_000217 COC(=O)c1sccc1OC(=O)c2nn(nc2C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J20 compound treatment 0.217 0.00412 0.06 0.226 0.0195 0.33 0.273 0.8214 3063294 Maybridge4_000218 Cc1ccc(/C=C/c2onc3c(=O)n(C)nc(C)c23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J21 compound treatment 0.207 -0.00588 -0.08 0.208 0.00148 0.02 -0.0418 -0.477 3063295 Maybridge4_000219 CCCC/1=NN(C(=O)\C1=C\c2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J22 compound treatment 0.238 0.0251 0.36 0.23 0.0235 0.39 0.5328 0.9989 3063296 Maybridge4_000220 CN(C(=O)CSc1ccc(cn1)C(F)(F)F)c2c3CCCCc3nn2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J23 mock treatment 0.195 -0.0179 -0.26 0.182 -0.0245 -0.41 -0.4718 -0.9738 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 J24 mock treatment 0.21 -0.00288 -0.04 0.202 -0.00452 -0.08 -0.0827 -0.9587 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K01 compound treatment 0.256 0.0431 0.62 0.276 0.0695 1.17 1.2608 0.9557 1220864 Maybridge4_000221 CC(C)(C)c1cc(CN2C(=O)c3ccccc3C2=O)cc(c1O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K02 compound treatment 0.238 0.0251 0.36 0.254 0.0475 0.8 0.8177 0.9353 3063297 Maybridge4_000222 Cc1cc2CSC(SCc2cc1C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K03 compound treatment 0.295 0.0821 1.17 0.248 0.0415 0.7 1.323 0.9688 3178205 Maybridge4_000223 FC(F)(F)Oc1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K04 compound treatment 0.287 0.0741 1.06 0.273 0.0665 1.12 1.5388 0.9997 3063298 Maybridge4_000224 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3oc(=O)ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K05 compound treatment 0.307 0.0941 1.35 0.271 0.0645 1.08 1.7173 0.9941 3178206 Maybridge4_000225 FC(F)(F)c1ccc(/C=C(\C#N)/c2cccc(c2)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K06 compound treatment 0.213 1.25E-4 0.0 0.264 0.0575 0.96 0.6835 0.7084 1672405 Maybridge4_000226 Clc1cccc(NC(=S)N2CCc3ccccc3C2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K07 compound treatment 0.244 0.0311 0.45 0.227 0.0205 0.34 0.5579 0.9918 1231870 Maybridge4_000227 Fc1ccc(CN2CCCN(CC2)C(=O)Nc3cccc(Cl)c3Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K08 compound treatment 0.217 0.00412 0.06 0.216 0.00948 0.16 0.1543 0.9088 1729950 Maybridge4_000228 CC(C)N(Cc1ccc(cc1)N(C)C)C(=O)c2sc3ccccc3c2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K09 compound treatment 0.22 0.00712 0.1 0.26 0.0535 0.9 0.7068 0.7824 3178207 Maybridge4_000229 Cc1nc(ccc1C(=O)N2CCN(CC2)c3nc4ccc(Cl)cc4s3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K10 compound treatment 0.219 0.00612 0.09 0.258 0.0515 0.86 0.673 0.7748 1285643 Maybridge4_000230 Clc1ccc(cc1)N(CCc2ccccn2)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K11 compound treatment 0.236 0.0231 0.33 0.259 0.0525 0.88 0.8568 0.9105 3063299 Maybridge4_000231 Clc1ccc(Cl)c(c1)n2ccnc2SCCCN3C(=O)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K12 compound treatment 0.218 0.00512 0.07 0.304 0.0975 1.64 1.2088 0.738 1594434 Maybridge4_000232 COc1ccc(cc1)C(=O)CC2(O)C(=O)N(CN3CCOCC3)c4ccc(Br)cc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K13 compound treatment 0.249 0.0361 0.52 0.229 0.0225 0.38 0.6322 0.9881 3063300 Maybridge4_000233 Cc1ccc(cc1)S(=O)(=O)NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K14 compound treatment 0.175 -0.0379 -0.54 0.222 0.0155 0.26 -0.1993 -0.3317 1540061 Maybridge4_000234 CN1C(NC(=O)c2ccccc12)C3CCC=CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K15 compound treatment 0.22 0.00712 0.1 0.196 -0.0105 -0.18 -0.0527 -0.2588 3178208 Maybridge4_000235 CC(C)Nc1ncnc2scc(c3ccccc3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K16 compound treatment 0.151 -0.0619 -0.89 0.189 -0.0175 -0.29 -0.8337 -0.894 3063301 Maybridge4_000236 S=C(NCCCN1CCOCC1)N2CC3CCC(CC3)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K17 compound treatment 0.195 -0.0179 -0.26 0.274 0.0675 1.13 0.6201 0.5341 1631820 Maybridge4_000237 COc1ccc(NS(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K18 compound treatment 0.232 0.0191 0.27 0.283 0.0765 1.28 1.1012 0.839 3063302 Maybridge4_000238 Cc1cc(Oc2ccc(cc2n3cccc3)C(F)(F)F)cc(C)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K19 compound treatment 0.191 -0.0219 -0.31 0.27 0.0635 1.07 0.5322 0.4792 3178209 Maybridge4_000239 FC(F)(F)c1cnc(N2CCC(CC2)N3C(=O)CC4(CCCC4)C3=O)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K20 compound treatment 0.186 -0.0269 -0.38 0.186 -0.0205 -0.34 -0.5153 -0.9985 3063303 Maybridge4_000240 Clc1ccc(SC(=O)c2cccnc2Oc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K21 compound treatment 0.237 0.0241 0.35 0.206 -5.16E-4 -0.01 0.2379 0.6891 1673449 Maybridge4_000241 O=C1CCCCCCCCCCC1CN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K22 compound treatment 0.19 -0.0229 -0.33 0.205 -0.00152 -0.03 -0.2494 -0.7598 1443277 Maybridge4_000242 Nc1ccccc1C(=O)NCCc2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K23 mock treatment 0.22 0.00712 0.1 0.187 -0.0195 -0.33 -0.1596 -0.4651 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 K24 mock treatment 0.209 -0.00388 -0.06 0.213 0.00648 0.11 0.0378 0.3092 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L01 compound treatment 0.209 -0.00388 -0.06 0.219 0.0125 0.21 0.109 0.5028 1275035 Maybridge4_000243 COC(=O)c1ccc(C)c(NC(=O)c2ccncc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L02 compound treatment 0.288 0.0751 1.07 0.231 0.0245 0.41 1.0504 0.913 3178210 Maybridge4_000244 CN(C)/C=N/S(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L03 compound treatment 0.205 -0.00788 -0.11 0.23 0.0235 0.39 0.1991 0.4856 1520487 Maybridge4_000245 Clc1ccc(cc1)C(=O)CNC(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L04 compound treatment 0.203 -0.00987 -0.14 0.22 0.0135 0.23 0.0601 0.2255 3063304 Maybridge4_000246 Fc1ccc(cc1F)C2=CSC3=NCCCN23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L05 compound treatment 0.244 0.0311 0.45 0.225 0.0185 0.31 0.5342 0.9844 3178211 Maybridge4_000247 CCC1(CC)N/C(=N/c2ccc(F)cc2F)/SC1=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L06 compound treatment 0.236 0.0231 0.33 0.25 0.0435 0.73 0.75 0.9359 3063305 Maybridge4_000248 Cn1ncc(SCc2ccccc2)c(Cl)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L07 compound treatment 0.247 0.0341 0.49 0.237 0.0305 0.51 0.7069 0.9997 3178212 Maybridge4_000249 Cc1ccc(/N=C\2/NC(C)(C)C(=C)S2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L08 compound treatment 0.253 0.0401 0.57 0.22 0.0135 0.23 0.5659 0.9172 3178213 Maybridge4_000250 CC(=O)Nc1ccc(Oc2cncc(Cl)c2)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L09 compound treatment 0.251 0.0381 0.55 0.238 0.0315 0.53 0.7593 0.9999 3063306 Maybridge4_000251 CCOC(=S)SCc1ccc(cc1)C(=O)Oc2ccc(F)cc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L10 compound treatment 0.195 -0.0179 -0.26 0.208 0.00148 0.02 -0.1632 -0.6352 3178214 Maybridge4_000252 CC1(C)CN(C(=S)Nc2cccc(Cl)c2)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L11 compound treatment 0.214 0.00112 0.02 0.252 0.0455 0.76 0.5512 0.7219 3063307 Maybridge4_000253 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L12 compound treatment 0.292 0.0791 1.13 0.253 0.0465 0.78 1.352 0.9835 1389325 Maybridge4_000254 Cc1cc(cc(C)c1OCC(=O)NN)c2nn(C)c(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L13 compound treatment 0.234 0.0211 0.3 0.274 0.0675 1.13 1.0146 0.8655 3063308 Maybridge4_000255 CSc1ccc(OCOc2ccc(SC)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L14 compound treatment 0.217 0.00412 0.06 0.266 0.0595 1.0 0.7477 0.7476 3178215 Maybridge4_000256 CCOC(=O)c1c(F)c(F)c(c(F)c1F)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L15 compound treatment 0.228 0.0151 0.22 0.252 0.0455 0.76 0.6928 0.8731 3178216 Maybridge4_000257 CN1C(NC(=O)c2cc(Cl)ccc12)c3ccc(C#N)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L16 compound treatment 0.264 0.0511 0.73 0.281 0.0745 1.25 1.4011 0.9674 1354966 Maybridge4_000258 Cc1ccc(Oc2ncccc2C(=O)NCC(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L17 compound treatment 0.21 -0.00288 -0.04 0.279 0.0725 1.22 0.8312 0.6828 3178217 Maybridge4_000259 NC(=O)Nc1ccc2[nH]ncc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L18 compound treatment 0.266 0.0531 0.76 0.211 0.00448 0.08 0.5905 0.7734 3063309 Maybridge4_000260 COc1cc(C)nc2nc(nn12)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L19 compound treatment 0.301 0.0881 1.26 0.268 0.0615 1.03 1.621 0.9951 3178218 Maybridge4_000261 CSc1nncc(n1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L20 compound treatment 0.235 0.0221 0.32 0.233 0.0265 0.44 0.5381 0.9861 1483914 Maybridge4_000262 Cc1ccc(cc1)c2cc(n[nH]2)c3c(C)nn(C)c(=O)c3N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L21 compound treatment 0.227 0.0141 0.2 0.224 0.0175 0.29 0.3504 0.9834 1521640 Maybridge4_000263 Nc1ccccc1C(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L22 compound treatment 0.216 0.00312 0.04 0.228 0.0215 0.36 0.2866 0.7887 3178219 Maybridge4_000264 Cc1nc(cs1)c2cc(C#N)c(Sc3cccc(c3)C(F)(F)F)nc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L23 mock treatment 0.26 0.0471 0.67 0.255 0.0485 0.81 1.052 0.9956 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 L24 mock treatment 0.219 0.00612 0.09 0.207 4.84E-4 0.01 0.0677 0.7694 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M01 compound treatment 0.19 -0.0229 -0.33 0.195 -0.0115 -0.19 -0.368 -0.9685 3063310 Maybridge4_000265 Oc1ccccc1/N=C/C=N/c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M02 compound treatment 0.239 0.0261 0.37 0.273 0.0665 1.12 1.0533 0.895 3178220 Maybridge4_000266 CN(CCC#N)c1ccc(cc1)C2SCc3cc(C)c(C)cc3CS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M03 compound treatment 0.225 0.0121 0.17 0.222 0.0155 0.26 0.3064 0.9807 3063311 Maybridge4_000267 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M04 compound treatment 0.236 0.0231 0.33 0.258 0.0515 0.86 0.8449 0.9132 3178221 Maybridge4_000268 Cc1onc(c1C(=O)N2CCCc3cccc(C)c23)c4c(Cl)cccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M05 compound treatment 0.199 -0.0139 -0.2 0.21 0.00348 0.06 -0.099 -0.4784 1280324 Maybridge4_000269 Cc1c(Cl)cccc1NC(=S)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M06 compound treatment 0.24 0.0271 0.39 0.259 0.0525 0.88 0.8972 0.9321 1592820 Maybridge4_000270 Cc1ccccc1NC(=S)Nc2ccccc2C(=O)Nc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M07 compound treatment 0.22 0.00712 0.1 0.289 0.0825 1.38 1.051 0.7571 3178222 Maybridge4_000271 Cc1nc(ccc1C(=O)Oc2ccc(OC(F)(F)F)cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M08 compound treatment 0.224 0.0111 0.16 0.213 0.00648 0.11 0.1895 0.9828 1647940 Maybridge4_000272 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)c3cc(Cl)ccc3n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M09 compound treatment 0.237 0.0241 0.35 0.241 0.0345 0.58 0.6533 0.9695 3178223 Maybridge4_000273 Cc1ccc(NC(=S)N2CCC(CC2)Nc3nccc(n3)C(F)(F)F)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M10 compound treatment 0.216 0.00312 0.04 0.231 0.0245 0.41 0.3222 0.7794 1291651 Maybridge4_000274 CC(C)c1ccc(cc1)N(CCc2ccccn2)S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M11 compound treatment 0.204 -0.00888 -0.13 0.183 -0.0235 -0.39 -0.3689 -0.8896 3178308 Maybridge4_000275 FC(F)(F)c1cccnc1NCCNc2ncnc3scc(c4ccccc4)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M12 compound treatment 0.25 0.0371 0.53 0.24 0.0335 0.56 0.7729 0.9996 3178309 Maybridge4_000276 Fc1ccc(cc1)C2CN3C(=N2)C=Cc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M13 compound treatment 0.252 0.0391 0.56 0.263 0.0565 0.95 1.0661 0.9684 1327290 Maybridge4_000277 COC(=O)c1cc(C#N)c(C)nc1Sc2nccn2c3cc(Cl)ccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M14 compound treatment 0.261 0.0481 0.69 0.267 0.0605 1.02 1.2046 0.9821 1331303 Maybridge4_000278 O=C1NC(Nc2ccccc12)C3CCC=CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M15 compound treatment 0.185 -0.0279 -0.4 0.244 0.0375 0.63 0.1629 0.2187 1371250 Maybridge4_000279 CC(C)NS(=O)(=O)c1ccc(N2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M16 compound treatment 0.242 0.0291 0.42 0.263 0.0565 0.95 0.9649 0.9318 1643068 Maybridge4_000280 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)N2CC3CCC(CC3)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M17 compound treatment 0.216 0.00312 0.04 0.269 0.0625 1.05 0.7732 0.7366 1732462 Maybridge4_000281 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M18 compound treatment 0.3 0.0871 1.25 0.282 0.0755 1.27 1.7771 1.0 1423781 Maybridge4_000282 Cc1cc(ccc1Cl)C(=O)c2cc3cc(Cl)ccc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M19 compound treatment 0.196 -0.0169 -0.24 0.21 0.00348 0.06 -0.1293 -0.5207 3178310 Maybridge4_000283 Fc1cccc(Cl)c1CN2CCN(CCCNc3ncnc4scc(c5ccccc5)c34)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M20 compound treatment 0.247 0.0341 0.49 0.233 0.0265 0.44 0.6595 0.9989 3063131 Maybridge4_000284 NNC(=O)c1cccnc1Oc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M21 compound treatment 0.214 0.00112 0.02 0.238 0.0315 0.53 0.385 0.7283 3063132 Maybridge4_000285 Fc1ccc(/C=C/c2cccc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M22 compound treatment 0.189 -0.0239 -0.34 0.225 0.0185 0.31 -0.0221 -0.0479 3178311 Maybridge4_000286 Cc1ccc(SCCNC(=O)c2cccnc2Oc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M23 mock treatment 0.214 0.00112 0.02 0.041 -0.166 -2.78 -1.953 -0.703 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 M24 mock treatment 0.204 -0.00888 -0.13 0.21 0.00348 0.06 -0.0484 -0.3464 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N01 compound treatment 0.264 0.0511 0.73 0.221 0.0145 0.24 0.689 0.8941 1041669 Maybridge4_000287 O=C(CSCC(=O)c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N02 compound treatment 0.22 0.00712 0.1 0.239 0.0325 0.55 0.4576 0.825 3178312 Maybridge4_000288 COC(=O)c1cccnc1SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N03 compound treatment 0.251 0.0381 0.55 0.222 0.0155 0.26 0.5694 0.9425 3063133 Maybridge4_000289 Cc1ccccc1c2ncc(o2)c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N04 compound treatment 0.209 -0.00388 -0.06 0.242 0.0355 0.6 0.3819 0.6385 3178313 Maybridge4_000290 Fc1ccc(cc1F)C2=NNC3=NCCN3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N05 compound treatment 0.219 0.00612 0.09 0.257 0.0505 0.85 0.6611 0.7761 3178314 Maybridge4_000291 Clc1ccc(NC(=N)c2ccccc2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N06 compound treatment 0.223 0.0101 0.14 0.241 0.0345 0.58 0.5117 0.8576 1155893 Maybridge4_000292 CSc1nnc(SC)n1CCNC(=O)c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N07 compound treatment 0.249 0.0361 0.52 0.226 0.0195 0.33 0.5966 0.9756 3178315 Maybridge4_000293 CCc1cccc(CC)c1/N=C\2/NC(C)(C)C(=C)S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N08 compound treatment 0.261 0.0481 0.69 0.208 0.00148 0.02 0.5044 0.7322 3178316 Maybridge4_000294 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC2=NN(C(=O)C2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N09 compound treatment 0.218 0.00512 0.07 0.205 -0.00152 -0.03 0.0338 0.4361 1286323 Maybridge4_000295 COC(=O)c1sc2ccccc2c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N10 compound treatment 0.22 0.00712 0.1 0.261 0.0545 0.91 0.7187 0.7811 1418804 Maybridge4_000296 Nc1ccccc1Nc2nc(=O)n(Cc3ccc(Cl)cc3)cc2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N11 compound treatment 0.229 0.0161 0.23 0.274 0.0675 1.13 0.964 0.834 1326126 Maybridge4_000297 Cc1ccc(COn2c(nc3ccccc3c2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N12 compound treatment 0.198 -0.0149 -0.21 0.23 0.0235 0.39 0.1283 0.2863 1242548 Maybridge4_000298 Cc1ccn2c(=O)c(cnc2c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N13 compound treatment 0.235 0.0221 0.32 0.221 0.0145 0.24 0.3957 0.9915 3178317 Maybridge4_000299 N#Cc1ccc(OCOc2ccc(C#N)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N14 compound treatment 0.199 -0.0139 -0.2 0.191 -0.0155 -0.26 -0.3245 -0.991 3063134 Maybridge4_000300 CC(C)Sc1nnc(S)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N15 compound treatment 0.243 0.0301 0.43 0.259 0.0525 0.88 0.9276 0.9459 3178318 Maybridge4_000301 Cn1c(nc(=O)c2cc(Cl)ccc12)c3cc(Br)cs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N16 compound treatment 0.21 -0.00288 -0.04 0.236 0.0295 0.49 0.3208 0.6461 3178319 Maybridge4_000302 Cc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3N(CC=C)S(=O)(=O)c4ccc(C)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N17 compound treatment 0.19 -0.0229 -0.33 0.262 0.0555 0.93 0.4271 0.4327 3063135 Maybridge4_000303 Cc1onc(NC(=O)NC(=O)c2ccccc2F)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N18 compound treatment 0.248 0.0351 0.5 0.196 -0.0105 -0.18 0.2305 0.4328 3063136 Maybridge4_000304 CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccc(cn1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N19 compound treatment 0.243 0.0301 0.43 0.245 0.0385 0.65 0.7614 0.9806 3178320 Maybridge4_000305 Clc1cc(Cl)c2nc(Oc3cccc(c3)N4CCOCC4)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N20 compound treatment 0.202 -0.0109 -0.16 0.223 0.0165 0.28 0.0856 0.2698 3063137 Maybridge4_000306 CCOC(=O)c1nn(c2ccccc2)c(=N)c(C#N)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N21 compound treatment 0.273 0.0601 0.86 0.259 0.0525 0.88 1.231 0.9999 3178321 Maybridge4_000307 Cc1nn(nc1c2nnc(o2)c3ccc(Cl)c(Cl)c3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N22 compound treatment 0.22 0.00712 0.1 0.268 0.0615 1.03 0.8018 0.7732 3178322 Maybridge4_000308 Cc1nc(cs1)c2cc(C#N)c(Oc3ccc(cc3)C(F)(F)F)nc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N23 mock treatment 0.222 0.00912 0.13 0.21 0.00348 0.06 0.1336 0.9344 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 N24 mock treatment 0.215 0.00212 0.03 0.215 0.00848 0.14 0.1222 0.8391 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O01 compound treatment 0.229 0.0161 0.23 0.218 0.0115 0.19 0.2994 0.996 3063138 Maybridge4_000309 Cn1cc(c(n1)C(F)(F)F)S(=O)(=O)NCc2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O02 compound treatment 0.245 0.0321 0.46 0.223 0.0165 0.28 0.5206 0.9705 1336600 Maybridge4_000310 Clc1ccccc1n2c(n[nH]c2=S)C3CCCNC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O03 compound treatment 0.214 0.00112 0.02 0.243 0.0365 0.61 0.4444 0.7254 3063139 Maybridge4_000311 Cc1cccc(Cl)c1NC(=O)N2CCCN(CC2)c3ncccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O04 compound treatment 0.259 0.0461 0.66 0.247 0.0405 0.68 0.947 0.9999 3178323 Maybridge4_000312 CCOC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O05 compound treatment 0.261 0.0481 0.69 0.241 0.0345 0.58 0.896 0.9963 1600108 Maybridge4_000313 OC1CCN(CC1)C(=O)Nc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O06 compound treatment 0.186 -0.0269 -0.38 0.225 0.0185 0.31 -0.0525 -0.1062 1675860 Maybridge4_000314 CCN(Cc1cc(OC)c(OC)c(OC)c1)C(=S)Nc2cccc(SC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O07 compound treatment 0.182 -0.0309 -0.44 0.245 0.0385 0.65 0.1445 0.1846 3063188 Maybridge4_000315 Cc1nc(ccc1C(=O)NCC=C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O08 compound treatment 0.181 -0.0319 -0.46 0.234 0.0275 0.46 0.0038 0.0058 1638858 Maybridge4_000316 Cc1nc2cc(Cl)ccc2c(=O)n1CC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O09 compound treatment 0.2 -0.0129 -0.18 0.201 -0.00552 -0.09 -0.1957 -0.9494 1730664 Maybridge4_000317 CCOC(=O)c1cc(C(=O)OC)c(C)nc1N2CCC(CC2)NC3CCCCC3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O10 compound treatment 0.197 -0.0159 -0.23 0.208 0.00148 0.02 -0.143 -0.6258 1134448 Maybridge4_000318 Fc1ccc(NC(=S)N2CCCCC2CCN3CCOCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O11 compound treatment 0.185 -0.0279 -0.4 0.221 0.0145 0.24 -0.11 -0.2356 3063189 Maybridge4_000319 OC(=O)/C=C/C(=O)NC1CCN(CC1)c2nccc(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O12 compound treatment 0.223 0.0101 0.14 0.226 0.0195 0.33 0.3336 0.9329 3178324 Maybridge4_000320 C1C(N=C2C=Cc3ccccc3N12)c4ccc5ccccc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O13 compound treatment 0.208 -0.00488 -0.07 0.236 0.0295 0.49 0.3006 0.6015 1152090 Maybridge4_000321 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O14 compound treatment 0.19 -0.0229 -0.33 0.203 -0.00352 -0.06 -0.2731 -0.8214 1502131 Maybridge4_000322 Nc1n(nc2cc(O)nc(O)c12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O15 compound treatment 0.195 -0.0179 -0.26 0.198 -0.00852 -0.14 -0.2819 -0.9623 1406030 Maybridge4_000323 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2ccccc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O16 compound treatment 0.167 -0.0459 -0.66 0.219 0.0125 0.21 -0.3158 -0.4585 1015155 Maybridge4_000324 O=c1ccc(=O)n([nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O17 compound treatment 0.164 -0.0489 -0.7 0.176 -0.0305 -0.51 -0.8565 -0.9883 3178325 Maybridge4_000325 Cc1nc(nc(NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1Cl)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O18 compound treatment 0.163 -0.0499 -0.71 0.228 0.0215 0.36 -0.2495 -0.3121 3063190 Maybridge4_000326 Cc1cc(NC(=S)NC(C)(C)C)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O19 compound treatment 0.195 -0.0179 -0.26 0.216 0.00948 0.16 -0.0682 -0.2266 1373262 Maybridge4_000327 S=C(NC1CC1)N2CCCN(Cc3cccc4ccccc34)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O20 compound treatment 0.202 -0.0109 -0.16 0.217 0.0105 0.18 0.0144 0.0614 3178326 Maybridge4_000328 N#Cc1cccnc1Oc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O21 compound treatment 0.212 -8.75E-4 -0.01 0.21 0.00348 0.06 0.0325 0.5434 3178327 Maybridge4_000329 Cc1cc(C(=O)NN)c2cc(Br)ccc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O22 compound treatment 0.21 -0.00288 -0.04 0.212 0.00548 0.09 0.036 0.3572 3063191 Maybridge4_000330 CC(C)(C)NC(=S)Nc1cc(ccc1N2CCCCC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O23 mock treatment 0.2 -0.0129 -0.18 0.199 -0.00752 -0.13 -0.2194 -0.983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 O24 mock treatment 0.197 -0.0159 -0.23 0.241 0.0345 0.58 0.2487 0.4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P01 compound treatment 0.136 -0.0769 -1.1 0.114 -0.0925 -1.55 -1.8755 -0.9857 3178328 Maybridge4_000331 Fc1ccc(cc1Cl)C(=O)NC(=O)Nc2nnc(s2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P02 compound treatment 0.19 -0.0229 -0.33 0.195 -0.0115 -0.19 -0.368 -0.9685 3178329 Maybridge4_000332 CN(C)/C=C/1\C(=O)c2ccc(Cl)cc2N(Cc3c(F)cccc3Cl)S1(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P03 compound treatment 0.249 0.0361 0.52 0.242 0.0355 0.6 0.7865 0.9975 3063192 Maybridge4_000333 Fc1ccccc1C(=O)NC(=O)OCc2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P04 compound treatment 0.085 -0.128 -1.83 0.076 -0.131 -2.19 -2.8423 -0.996 3063193 Maybridge4_000334 CN1N=C(CC1=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P05 compound treatment 0.232 0.0191 0.27 0.222 0.0155 0.26 0.3772 0.9997 3178330 Maybridge4_000335 Clc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(=O)NCCCn3ccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P06 compound treatment 0.258 0.0451 0.65 0.26 0.0535 0.9 1.0912 0.9869 3063194 Maybridge4_000336 CN(C)/C=N/c1cc(Cl)c(cc1Oc2ccc(Cl)cc2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P07 compound treatment 0.227 0.0141 0.2 0.229 0.0225 0.38 0.4097 0.9571 3178331 Maybridge4_000337 CSC1=NCCN1CC(=O)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P08 compound treatment 0.21 -0.00288 -0.04 0.245 0.0385 0.65 0.4277 0.6607 3178429 Maybridge4_000338 Oc1c(C(=O)c2ccccc2)c(CS(=O)(=O)c3ccc(cn3)C(F)(F)F)nn1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P09 compound treatment 0.154 -0.0589 -0.84 0.157 -0.0495 -0.83 -1.1831 -1.0 3063195 Maybridge4_000339 FC(F)(F)c1ccc2[nH]c(SCc3cccc(C#N)c3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P10 compound treatment 0.253 0.0401 0.57 0.216 0.00948 0.16 0.5184 0.8704 3178430 Maybridge4_000340 COc1ccccc1N2CC(C)(C)C(=O)N(C(=O)c3ccc(C)cc3)C2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P11 compound treatment 0.257 0.0441 0.63 0.276 0.0695 1.17 1.2709 0.9584 1567114 Maybridge4_000341 Brc1ccc(COn2c(nc3ccccc3c2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P12 compound treatment 0.208 -0.00488 -0.07 0.216 0.00948 0.16 0.0632 0.364 1250229 Maybridge4_000342 CCCCN1C(C(=O)N(C1=O)c2nnc(s2)C(C)(C)C)c3ccc(Cl)c(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P13 compound treatment 0.223 0.0101 0.14 0.249 0.0425 0.71 0.6066 0.8337 3063196 Maybridge4_000343 COC(=O)/C=c/1\sc2nc3cc(Cl)c(Cl)cc3n2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P14 compound treatment 0.177 -0.0359 -0.51 0.197 -0.00952 -0.16 -0.4758 -0.8853 3178431 Maybridge4_000344 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCOC(=O)c2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P15 compound treatment 0.194 -0.0189 -0.27 0.245 0.0385 0.65 0.2658 0.3797 3063197 Maybridge4_000345 CC(C)(C)SCCNc1nc(Oc2ccc(F)cc2)nc(Oc3ccc(F)cc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P16 compound treatment 0.16 -0.0529 -0.76 0.202 -0.00452 -0.08 -0.5884 -0.7741 3178432 Maybridge4_000346 N=C1CC(=O)N=C2SC(=NN21)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P17 compound treatment 0.238 0.0251 0.36 0.239 0.0325 0.55 0.6396 0.9795 3063198 Maybridge4_000347 COC(=O)/C(=C/N(C)C)/Sc1cc(C)c(Cl)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P18 compound treatment 0.223 0.0101 0.14 0.191 -0.0155 -0.26 -0.0817 -0.2743 3178433 Maybridge4_000348 CSc1nc(C)nc(Sc2ccccc2)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P19 compound treatment 0.211 -0.00188 -0.03 0.231 0.0245 0.41 0.2716 0.6596 3178434 Maybridge4_000349 Cc1cc(Oc2nc3cc(Cl)ccc3s2)c4cc(Cl)ccc4n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P20 compound treatment 0.221 0.00812 0.12 0.218 0.0115 0.19 0.2185 0.9707 1222979 Maybridge4_000350 CSC1=NN(C)c2cnn(C)c(=O)c2S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P21 compound treatment 0.24 0.0271 0.39 0.247 0.0405 0.68 0.7548 0.9647 1579106 Maybridge4_000351 O=C(CC#N)NCc1ccccn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P22 compound treatment 0.235 0.0221 0.32 0.241 0.0345 0.58 0.633 0.9597 1689187 Maybridge4_000352 Clc1ccc(SCC(=O)c2ccc3NC(=O)CCc3c2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P23 mock treatment 0.227 0.0141 0.2 0.228 0.0215 0.36 0.3978 0.9625 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2049 P24 mock treatment 0.173 -0.0399 -0.57 0.171 -0.0355 -0.6 -0.8248 -0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A01 compound treatment 0.259 0.0446 0.64 0.221 0.00569 0.1 0.5182 0.804 3063199 Maybridge4_000353 O=C1CCc2cc(ccc2N1)C3=CSC4=NCCN34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A02 compound treatment 0.247 0.0326 0.47 0.212 -0.00331 -0.06 0.29 0.6183 3178435 Maybridge4_000354 CC1(C)OC(=O)C(C2C3CC4CC(C3)CC2C4)C(=O)O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A03 compound treatment 0.245 0.0306 0.44 0.217 0.00169 0.03 0.3291 0.7513 3178436 Maybridge4_000355 Cc1nc(cs1)c2cc(C#N)c(SCCNC(=O)c3ccc(Cl)cc3Cl)nc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A04 compound treatment 0.238 0.0236 0.34 0.243 0.0277 0.46 0.5669 0.9876 1602887 Maybridge4_000356 CC1(C)Oc2c(C=C1)c3c(=O)cc(oc3c4ccoc24)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A05 compound treatment 0.225 0.0106 0.15 0.233 0.0177 0.3 0.3167 0.9509 3063200 Maybridge4_000357 COc1cc(OC)nc(/N=C/N(C)C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A06 compound treatment 0.219 0.00456 0.07 0.204 -0.0113 -0.19 -0.0881 -0.4389 3178437 Maybridge4_000358 CC1(C)CN=C(NC2CCCCC2)S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A07 compound treatment 0.254 0.0396 0.57 0.236 0.0207 0.35 0.6457 0.9725 3178438 Maybridge4_000359 COc1ccc(CCC(=O)CCc2ccc(OC)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A08 compound treatment 0.23 0.0156 0.22 0.203 -0.0123 -0.21 0.0113 0.0371 3063201 Maybridge4_000360 COc1ccccc1OC(=O)NC(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A09 compound treatment 0.212 -0.00244 -0.03 0.193 -0.0223 -0.37 -0.2895 -0.7696 3178439 Maybridge4_000361 CCOC(=O)c1ccc(cc1)C(=S)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A10 compound treatment 0.241 0.0266 0.38 0.212 -0.00331 -0.06 0.2293 0.5973 1174208 Maybridge4_000362 CCC1(CCCCN(C)C1=O)c2cccc(OC(=O)C3CCCCC3)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A11 compound treatment 0.22 0.00556 0.08 0.201 -0.0143 -0.24 -0.1136 -0.4489 3063202 Maybridge4_000363 CN(C)Cc1c(C)cc(C)cc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A12 compound treatment 0.205 -0.00944 -0.13 0.192 -0.0233 -0.39 -0.3721 -0.8991 1469863 Maybridge4_000364 O=C(Nc1nc(cs1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A13 compound treatment 0.228 0.0136 0.19 0.211 -0.00431 -0.07 0.086 0.4153 1002608 Maybridge4_000365 CCOC(=O)c1cnc(S)nc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A14 compound treatment 0.213 -0.00144 -0.02 0.206 -0.00931 -0.16 -0.1251 -0.7933 1583969 Maybridge4_000366 Clc1cccc(c1)C(=O)NC2CN3CCC2CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A15 compound treatment 0.197 -0.0174 -0.25 0.203 -0.0123 -0.21 -0.3225 -0.9956 3063203 Maybridge4_000367 COc1cc(C#N)c2ccc3ccccc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A16 compound treatment 0.233 0.0186 0.27 0.214 -0.00131 -0.02 0.1722 0.6462 3178440 Maybridge4_000368 CCNC(=Nc1ccc(Cl)cc1)NCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A17 compound treatment 0.23 0.0156 0.22 0.221 0.00569 0.1 0.2249 0.9286 1368926 Maybridge4_000369 CC(=O)OCc1ccccc1Sc2ccccc2C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A18 compound treatment 0.202 -0.0124 -0.18 0.204 -0.0113 -0.19 -0.2601 -0.9995 1219932 Maybridge4_000370 C1C=C(Nc2nnnn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A19 compound treatment 0.228 0.0136 0.19 0.21 -0.00531 -0.09 0.0741 0.3472 1528436 Maybridge4_000371 Cn1c(nc2ccccc12)N3C(=O)c4cccc5cccc(C3=O)c45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A20 compound treatment 0.218 0.00356 0.05 0.177 -0.0383 -0.64 -0.4187 -0.649 1375750 Maybridge4_000372 CC1(CC2CC3(C)C1)CC(C2)(C3)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A21 compound treatment 0.222 0.00756 0.11 0.21 -0.00531 -0.09 0.0134 0.0959 1405005 Maybridge4_000373 O=c1nc2sc3ccccc3n2c(=O)n1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A22 compound treatment 0.206 -0.00844 -0.12 0.197 -0.0183 -0.31 -0.3027 -0.9166 3063251 Maybridge4_000374 C/S(=N\S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A23 mock treatment 0.228 0.0136 0.19 0.235 0.0197 0.33 0.3708 0.9678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 A24 mock treatment 0.226 0.0116 0.17 0.217 0.00169 0.03 0.137 0.8163 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B01 compound treatment 0.239 0.0246 0.35 0.234 0.0187 0.31 0.4702 0.9984 3063252 Maybridge4_000375 C1CN(C1)C(c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B02 compound treatment 0.248 0.0336 0.48 0.243 0.0277 0.46 0.6681 0.9999 3063253 Maybridge4_000376 CC1CCC(C)N1c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B03 compound treatment 0.197 -0.0174 -0.25 0.174 -0.0413 -0.69 -0.6667 -0.9047 3063254 Maybridge4_000377 Cc1ccc(cc1)S(=O)(=O)C[C@H]2O[C@H](C[C@@H]2O)n3cc(I)c(=O)[nH]c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B04 compound treatment 0.253 0.0386 0.55 0.225 0.00969 0.16 0.505 0.8782 3063255 Maybridge4_000378 C/C(=N\O)/c1cc(Cl)cc(Cl)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B05 compound treatment 0.223 0.00856 0.12 0.25 0.0347 0.58 0.4983 0.8375 3063256 Maybridge4_000379 CCN(CC)Cc1c(C)c(C)c(C)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B06 compound treatment 0.081 -0.133 -1.91 0.074 -0.141 -2.37 -3.0267 -0.9942 3178441 Maybridge4_000380 Oc1c(Cl)cc(Cl)cc1C2Nc3cc(ccc3-n4cccc24)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B07 compound treatment 0.26 0.0456 0.65 0.245 0.0297 0.5 0.8132 0.9912 1227211 Maybridge4_000381 CCC(C)(C)NC(=S)Nc1cccc(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B08 compound treatment 0.243 0.0286 0.41 0.222 0.00669 0.11 0.3683 0.8692 3178442 Maybridge4_000382 Cc1c(C)c(C)c2[nH]c(SCc3nc(no3)c4ccc(Cl)cc4)nc2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B09 compound treatment 0.232 0.0176 0.25 0.24 0.0247 0.41 0.4706 0.9712 3063257 Maybridge4_000383 CSC1=C(C#N)C(=O)NC(S1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B10 compound treatment 0.256 0.0416 0.59 0.239 0.0237 0.4 0.7015 0.9809 3178443 Maybridge4_000384 C/C(=N\Cc1ccccc1)/c2c(C)cc(C)cc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B11 compound treatment 0.247 0.0326 0.47 0.242 0.0267 0.45 0.6461 0.9998 1417340 Maybridge4_000385 COc1cc(cc(OC)c1OC)C2Nc3ccccc3S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B12 compound treatment 0.23 0.0156 0.22 0.204 -0.0113 -0.19 0.0231 0.0791 1464378 Maybridge4_000386 N#CC1CN(CCc2ccccc2)CN(CCc3ccccc3)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B13 compound treatment 0.243 0.0286 0.41 0.221 0.00569 0.1 0.3564 0.8494 1213608 Maybridge4_000387 COc1cc(CO)c(CC(=O)NN)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B14 compound treatment 0.222 0.00756 0.11 0.23 0.0147 0.25 0.2508 0.9316 1103050 Maybridge4_000388 CC1(C)OC(=O)C(=Cc2ccc[nH]2)C(=O)O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B15 compound treatment 0.232 0.0176 0.25 0.225 0.00969 0.16 0.2926 0.9778 1559616 Maybridge4_000389 COc1cc(OC)cc(c1)c2nc(N)c3c(C)c(sc3n2)c4ccc(OC)c(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B16 compound treatment 0.247 0.0326 0.47 0.216 6.88E-4 0.01 0.3375 0.7244 1513039 Maybridge4_000390 Cc1onc(c1NC(=O)N2CCCC2=O)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B17 compound treatment 0.259 0.0446 0.64 0.243 0.0277 0.46 0.7793 0.9879 1918178 Maybridge4_000391 Cc1ccc(NC(=O)C2C(C3CC2C=C3)C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B18 compound treatment 0.228 0.0136 0.19 0.226 0.0107 0.18 0.264 0.9992 3178444 Maybridge4_000392 CS/C(=N\c1ccccc1C(F)(F)F)/N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B19 compound treatment 0.199 -0.0154 -0.22 0.075 -0.14 -2.36 -1.8214 -0.77 3178445 Maybridge4_000393 CCOC(=O)c1nc2ccccc2c(=O)n1/N=C/c3cc(Cl)cc(Cl)c3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B20 compound treatment 0.235 0.0206 0.29 0.204 -0.0113 -0.19 0.0737 0.2106 3063259 Maybridge4_000394 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B21 compound treatment 0.244 0.0296 0.42 0.227 0.0117 0.2 0.4377 0.939 3063260 Maybridge4_000395 CSC(=NS(=O)(=O)c1ccccc1)SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B22 compound treatment 0.242 0.0276 0.39 0.244 0.0287 0.48 0.6192 0.9951 1232359 Maybridge4_000396 Cc1onc(c1C(=O)ON2C(=O)CCC2=O)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B23 mock treatment 0.26 0.0456 0.65 0.256 0.0407 0.68 0.9437 0.9997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 B24 mock treatment 0.231 0.0166 0.24 0.227 0.0117 0.2 0.3062 0.9956 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C01 compound treatment 0.208 -0.00644 -0.09 0.23 0.0147 0.25 0.1092 0.415 3063261 Maybridge4_000397 CN(C(=O)COc1cc(n(C)n1)C(F)(F)F)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C02 compound treatment 0.213 -0.00144 -0.02 0.209 -0.00631 -0.11 -0.0895 -0.8289 1015362 Maybridge4_000398 CCOC(=O)c1cccc2C(=O)c3ccccc3-c21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C03 compound treatment 0.221 0.00656 0.09 0.248 0.0327 0.55 0.4543 0.8162 1410184 Maybridge4_000399 Cc1ccc(Oc2ncccc2NC(=O)c3ccc(Cl)cc3Cl)c4CCCc41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C04 compound treatment 0.221 0.00656 0.09 0.214 -0.00131 -0.02 0.0508 0.5268 1430911 Maybridge4_000400 OC(=O)CCC(=O)c1ccc2OCCCOc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C05 compound treatment 0.043 -0.171 -2.45 0.212 -0.00331 -0.06 -1.7733 -0.723 3063262 Maybridge4_000401 COc1cc(OC)nc(N/C=N/O)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C06 compound treatment 0.203 -0.0114 -0.16 0.239 0.0237 0.4 0.1654 0.3848 1594886 Maybridge4_000402 Cn1c(=O)cc(Nc2ccccc2)c3c(=O)n(c4ccccc4)c(=O)n(c5ccccc5)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C07 compound treatment 0.046 -0.168 -2.41 0.222 0.00669 0.11 -1.6242 -0.6734 3063263 Maybridge4_000403 OC(=O)c1cc(=O)c2c(O)cccc2o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C08 compound treatment 0.222 0.00756 0.11 0.189 -0.0263 -0.44 -0.2358 -0.5186 3063264 Maybridge4_000404 CC(C)NC(=O)Oc1cccc(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C09 compound treatment 0.238 0.0236 0.34 0.203 -0.0123 -0.21 0.0922 0.2332 3178446 Maybridge4_000405 COC(=O)c1ccc(cc1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C10 compound treatment 0.051 -0.163 -2.34 0.25 0.0347 0.58 -1.2414 -0.5153 1676301 Maybridge4_000406 COC(=O)C1C(NC(C(C(=O)OC)S1(=O)=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C11 compound treatment 0.199 -0.0154 -0.22 0.205 -0.0103 -0.17 -0.2785 -0.9927 3063265 Maybridge4_000407 O=C1CC(=NN1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C12 compound treatment 0.051 -0.163 -2.34 0.144 -0.0713 -1.2 -2.4994 -0.9517 1343081 Maybridge4_000408 CC(C1CC1)N(C(=O)c2cc(C)c(Cl)cc2Cl)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C13 compound treatment 0.122 -0.0924 -1.32 0.112 -0.103 -1.73 -2.1611 -0.991 1138226 Maybridge4_000409 COc1ccc2c(c1)nnc3n[nH]c(=O)n32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C14 compound treatment 0.193 -0.0214 -0.31 0.22 0.00469 0.08 -0.1612 -0.5092 1419670 Maybridge4_000410 OC(=O)CNC(=O)CSc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C15 compound treatment 0.21 -0.00444 -0.06 0.216 6.88E-4 0.01 -0.0367 -0.5692 3063266 Maybridge4_000411 CC1=C(C#N)C(C(=C(C)N1)C#N)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C16 compound treatment 0.166 -0.0484 -0.69 0.177 -0.0383 -0.64 -0.9446 -0.9993 3178530 Maybridge4_000412 CCC1(CCCCN(C)C1=O)c2cccc(OC(=O)Nc3ccc(OC(F)(F)F)cc3)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C17 compound treatment 0.163 -0.0514 -0.74 0.125 -0.0903 -1.52 -1.5921 -0.9449 1346230 Maybridge4_000413 N#Cc1cccc2cccc(Sc3ccccc3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C18 compound treatment 0.217 0.00256 0.04 0.216 6.88E-4 0.01 0.0341 0.8868 1555561 Maybridge4_000414 COc1ccc(OC)c(CCCc2cc(OC)ccc2OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C19 compound treatment 0.225 0.0106 0.15 0.207 -0.00831 -0.14 0.0082 0.0398 3063267 Maybridge4_000415 CCN(CC)C(=O)Nc1ccc(OC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C20 compound treatment 0.211 -0.00344 -0.05 0.198 -0.0173 -0.29 -0.2402 -0.8152 1920088 Maybridge4_000416 S=c1nc(c2ccco2)n(Cc3ccccc3)c(=S)n1/C(=N/Cc4ccccc4)/c5ccco5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C21 compound treatment 0.208 -0.00644 -0.09 0.198 -0.0173 -0.29 -0.2706 -0.8877 3178531 Maybridge4_000417 FC(F)(F)c1cccc(c1)c2nc3ccccn3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C22 compound treatment 0.226 0.0116 0.17 0.217 0.00169 0.03 0.137 0.8163 3178532 Maybridge4_000418 O=C(/C=C\1/NN=C(NC1=O)c2ccccc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C23 mock treatment 0.216 0.00156 0.02 0.181 -0.0343 -0.58 -0.3914 -0.6792 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 C24 mock treatment 0.186 -0.0284 -0.41 0.214 -0.00131 -0.02 -0.3032 -0.7443 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D01 compound treatment 0.283 0.0686 0.98 0.265 0.0497 0.83 1.2832 0.9967 3178533 Maybridge4_000419 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3NC(=O)[C@H]([C@@H]3c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D02 compound treatment 0.221 0.00656 0.09 0.225 0.00969 0.16 0.1813 0.9659 3063268 Maybridge4_000420 FC(F)(F)c1cc(c(Br)c(c1Br)n2cccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D03 compound treatment 0.065 -0.149 -2.14 0.06 -0.155 -2.61 -3.3547 -0.9951 1316662 Maybridge4_000421 Clc1ccc(NC(=S)NC(Cn2ccnc2)c3ccccc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D04 compound treatment 0.208 -0.00644 -0.09 0.217 0.00169 0.03 -0.0451 -0.468 1725083 Maybridge4_000422 Cc1c(N)c2c(cc1N3CCCC3)C(C)(C)CC2(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D05 compound treatment 0.259 0.0446 0.64 0.198 -0.0173 -0.29 0.2452 0.3501 1718122 Maybridge4_000423 C1c2sc(Nc3ccccc3)nc2-c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D06 compound treatment 0.244 0.0296 0.42 0.246 0.0307 0.52 0.6632 0.9952 3178534 Maybridge4_000424 FC(F)(F)c1cc(cc(c1)S(=O)(=O)N=C2NCCCN2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D07 compound treatment 0.296 0.0816 1.17 0.237 0.0217 0.36 1.0823 0.8856 1138900 Maybridge4_000425 CC(C)(C)NC(=O)NCc1ccncc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D08 compound treatment 0.232 0.0176 0.25 0.231 0.0157 0.26 0.3638 0.9997 3178535 Maybridge4_000426 FC(F)(F)c1cc(NCN2C(=O)CCC2=O)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D09 compound treatment 0.242 0.0276 0.39 0.215 -3.12E-4 -0.01 0.2751 0.6976 3178536 Maybridge4_000427 COc1cccc(NC2=C(C#N)C(=O)NC(S2)c3cccc(OC)c3O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D10 compound treatment 0.225 0.0106 0.15 0.251 0.0357 0.6 0.5304 0.8586 3063269 Maybridge4_000428 Clc1ccc(cc1)S(=O)(=O)CS(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D11 compound treatment 0.246 0.0316 0.45 0.284 0.0687 1.15 1.1344 0.9163 1023491 Maybridge4_000429 Oc1ccc(Br)cc1C2Nc3ccccc3S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D12 compound treatment 0.242 0.0276 0.39 0.288 0.0727 1.22 1.1414 0.8903 3178537 Maybridge4_000430 C/C(=N\O)/c1nnn(c1C)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D13 compound treatment 0.269 0.0546 0.78 0.233 0.0177 0.3 0.7618 0.9123 1381610 Maybridge4_000431 CC1(C)C2CCC(C2)C1(C)NC(=S)NCC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D14 compound treatment 0.252 0.0376 0.54 0.257 0.0417 0.7 0.8747 0.9915 3178538 Maybridge4_000432 FC(F)(F)c1cccc(CS(=O)(=O)Cc2cccc(c2)C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D15 compound treatment 0.241 0.0266 0.38 0.222 0.00669 0.11 0.348 0.8785 1650135 Maybridge4_000433 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)NCc3cccnc3)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D16 compound treatment 0.226 0.0116 0.17 0.255 0.0397 0.67 0.588 0.8567 1002759 Maybridge4_000434 OC(C(O)C(O)c1nc2ccccc2[nH]1)C(O)c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D17 compound treatment 0.283 0.0686 0.98 0.307 0.0917 1.54 1.7816 0.9763 1658002 Maybridge4_000435 Cc1c(C)c(C)c(CSC2CC(=O)N(C2=O)c3ccccc3)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D18 compound treatment 0.28 0.0656 0.94 0.242 0.0267 0.45 0.9798 0.9428 3062531 Maybridge4_000436 Clc1ccc(cc1Cl)S(=O)(=O)NC(=N)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D19 compound treatment 0.229 0.0146 0.21 0.248 0.0327 0.55 0.5352 0.9121 2117992 Maybridge4_000437 COc1cccc(/C=N/O)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D20 compound treatment 0.204 -0.0104 -0.15 0.21 -0.00531 -0.09 -0.1686 -0.9696 1204180 Maybridge4_000438 Clc1ccc(cc1Cl)S(=O)(=O)NCCc2c[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D21 compound treatment 0.224 0.00956 0.14 0.242 0.0267 0.45 0.4134 0.8828 3062533 Maybridge4_000439 CS/C(=N\S(=O)(=O)c1ccccc1)/N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D22 compound treatment 0.244 0.0296 0.42 0.271 0.0557 0.93 0.9599 0.9357 1417838 Maybridge4_000440 COC(=O)CC1(Oc2ccc(Br)cc2C(=O)N1c3ccc(F)cc3F)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D23 mock treatment 0.253 0.0386 0.55 0.219 0.00369 0.06 0.4338 0.7815 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 D24 mock treatment 0.186 -0.0284 -0.41 0.226 0.0107 0.18 -0.1608 -0.3617 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E01 compound treatment 0.231 0.0166 0.24 0.234 0.0187 0.31 0.3893 0.9904 3062534 Maybridge4_000441 Cn1nc(OC(C)(C)C(=O)Oc2ccc(Cl)cc2Cl)cc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E02 compound treatment 0.227 0.0126 0.18 0.238 0.0227 0.38 0.3963 0.9412 1024184 Maybridge4_000442 CCC(=O)c1ccc(OC)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E03 compound treatment 0.241 0.0266 0.38 0.243 0.0277 0.46 0.5973 0.995 1519339 Maybridge4_000443 Cc1ccc(Oc2ncccc2NC(=O)CSc3ccccn3)c4CCCc41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E04 compound treatment 0.246 0.0316 0.45 0.236 0.0207 0.35 0.5648 0.9916 3062535 Maybridge4_000444 Cc1cc(=O)n(CCO)c(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E05 compound treatment 0.254 0.0396 0.57 0.238 0.0227 0.38 0.6694 0.9814 3178539 Maybridge4_000445 OC(=O)CC(C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C2=CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E06 compound treatment 0.248 0.0336 0.48 0.267 0.0517 0.87 0.9529 0.9611 1643916 Maybridge4_000446 O=C(N1CCCCC1)c2cccc3Cc4ccccc4-c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E07 compound treatment 0.248 0.0336 0.48 0.264 0.0487 0.82 0.9173 0.9679 3178540 Maybridge4_000447 OC(=O)c1oc(C(=O)O)c(OCc2ccccc2)c1OCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E08 compound treatment 0.296 0.0816 1.17 0.2 -0.0153 -0.26 0.6432 0.5384 3062536 Maybridge4_000448 O=C(Oc1ccccc1)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E09 compound treatment 0.271 0.0566 0.81 0.194 -0.0213 -0.36 0.3191 0.3608 1039079 Maybridge4_000449 OC(=O)c1cccc(Cl)c1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E10 compound treatment 0.265 0.0506 0.72 0.229 0.0137 0.23 0.6738 0.888 1423015 Maybridge4_000450 CC(=O)N[C@@H](Cc1ccccc1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E11 compound treatment 0.267 0.0526 0.75 0.286 0.0707 1.19 1.3706 0.9758 3178542 Maybridge4_000451 OC(Cn1ccccc1=N)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E12 compound treatment 0.241 0.0266 0.38 0.274 0.0587 0.99 0.9652 0.9142 3062537 Maybridge4_000452 CC(C1CC1)N(C(=O)C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E13 compound treatment 0.237 0.0226 0.32 0.237 0.0217 0.36 0.4856 0.9982 1704451 Maybridge4_000453 CN(C)C(=O)c1cccc2C(=O)c3ccccc3-c21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E14 compound treatment 0.244 0.0296 0.42 0.252 0.0367 0.62 0.7344 0.9832 3178543 Maybridge4_000454 CC(C)(C)C(=O)Nc1ccn([C@H]2C[C@H](O)[C@@H](COC(=O)C(C)(C)C)O2)c(=O)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E15 compound treatment 0.162 -0.0524 -0.75 0.144 -0.0713 -1.2 -1.3767 -0.9747 3062540 Maybridge4_000455 COc1ccc2c(OC)ccc3C(=O)C=Cc1c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E16 compound treatment 0.269 0.0546 0.78 0.258 0.0427 0.72 1.0585 0.9991 1289531 Maybridge4_000456 Clc1ccc(cc1)C(=O)OC2CN3CCC2CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E17 compound treatment 0.247 0.0326 0.47 0.254 0.0387 0.65 0.7885 0.9867 1672892 Maybridge4_000457 CNC(=O)c1ccccc1S(=O)c2cccc3cccc(C(=O)O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E18 compound treatment 0.25 0.0356 0.51 0.205 -0.0103 -0.17 0.2373 0.4416 3062541 Maybridge4_000458 COc1ccc(OC)c(CCCCc2cc(OC)ccc2OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E19 compound treatment 0.219 0.00456 0.07 0.199 -0.0163 -0.27 -0.1475 -0.5239 3178544 Maybridge4_000459 Clc1ccc(S/C=C/C(=O)c2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E20 compound treatment 0.216 0.00156 0.02 0.247 0.0317 0.53 0.3919 0.7362 3062542 Maybridge4_000460 C/C(=N\O)/C1(CC2(C)CC3(C)CC(C)(C2)C1)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E21 compound treatment 0.241 0.0266 0.38 0.206 -0.00931 -0.16 0.1581 0.3849 3178545 Maybridge4_000461 CC(=O)OC[C@H]1O[C@@H](Nc2ccc(C)cc2)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E22 compound treatment 0.2 -0.0144 -0.21 0.214 -0.00131 -0.02 -0.1616 -0.7781 3062543 Maybridge4_000462 CC1(C)N(O)C(NC1=S)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E23 mock treatment 0.218 0.00356 0.05 0.215 -3.12E-4 -0.01 0.0323 0.631 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 E24 mock treatment 0.218 0.00356 0.05 0.227 0.0117 0.2 0.1747 0.8622 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F01 compound treatment 0.247 0.0326 0.47 0.231 0.0157 0.26 0.5155 0.9635 3178546 Maybridge4_000463 Fc1ccc2CC(=O)C(Cc2c1)C3=Cc4ccc(F)cc4CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F02 compound treatment 0.222 0.00756 0.11 0.21 -0.00531 -0.09 0.0134 0.0959 1526672 Maybridge4_000464 COc1ccc(CCNC(=O)c2nc3ccccc3c(=O)n2n4cccc4)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F03 compound treatment 0.238 0.0236 0.34 0.228 0.0127 0.21 0.3889 0.9755 3062544 Maybridge4_000465 CC(OC(=O)c1cccc(Cl)c1)c2ccc[n+](C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F04 compound treatment 0.268 0.0536 0.77 0.256 0.0407 0.68 1.0246 0.9984 1352177 Maybridge4_000466 CSc1cccc(NC(=S)Nc2cc3c(c(N)c2C)C(C)(C)CC3(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F05 compound treatment 0.279 0.0646 0.92 0.259 0.0437 0.73 1.1715 0.9935 3062545 Maybridge4_000467 CC(C=C1C(=O)NC(=O)NC1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F06 compound treatment 0.219 0.00456 0.07 0.234 0.0187 0.31 0.2679 0.8363 3062546 Maybridge4_000468 SC1=NC2(CCCC2)NN1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F07 compound treatment 0.267 0.0526 0.75 0.267 0.0517 0.87 1.1451 0.9975 3178547 Maybridge4_000469 C(c1ccc(/N=C/c2ccccn2)cc1)c3ccc(/N=C/c4ccccn4)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F08 compound treatment 0.268 0.0536 0.77 0.294 0.0787 1.32 1.4756 0.9665 1528873 Maybridge4_000470 O=C1CCC(=O)N1CNc2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F09 compound treatment 0.299 0.0846 1.21 0.285 0.0697 1.17 1.6823 0.9999 1318293 Maybridge4_000471 CC(C)(C)C(=O)Nc1ccccc1C(=O)NCc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F10 compound treatment 0.148 -0.0664 -0.95 0.166 -0.0493 -0.83 -1.2572 -0.9976 3178548 Maybridge4_000472 Clc1ccc(SCc2ccc(NC(=O)Nc3cccc(Cl)c3)o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F11 compound treatment 0.219 0.00456 0.07 0.245 0.0297 0.5 0.3985 0.7929 3062547 Maybridge4_000473 NC(=N)Nc1nc(cs1)c2ccc(cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F12 compound treatment 0.211 -0.00344 -0.05 0.172 -0.0433 -0.73 -0.5488 -0.7532 3178625 Maybridge4_000474 CS/C(=C(/C#N)\C(=O)c1cccs1)/Nc2cccc(Cl)c2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F13 compound treatment 0.321 0.107 1.52 0.311 0.0957 1.61 2.2134 0.9997 3178626 Maybridge4_000475 OC(Cc1ccccc1)(c2ccccc2)c3ccccc3NC(=S)NC4CC5CC4C=C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F14 compound treatment 0.29 0.0756 1.08 0.279 0.0637 1.07 1.5201 1.0 3062548 Maybridge4_000476 Cc1nnsc1C(=O)Nc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F15 compound treatment 0.309 0.0946 1.35 0.293 0.0777 1.3 1.8784 0.9998 1004988 Maybridge4_000477 ON=C(Cc1ccccc1)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F16 compound treatment 0.271 0.0566 0.81 0.272 0.0567 0.95 1.2449 0.9967 3178627 Maybridge4_000478 Cc1onc(c1C(=O)NC(=S)N2CCOCC2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F17 compound treatment 0.255 0.0406 0.58 0.267 0.0517 0.87 1.0237 0.9809 3062549 Maybridge4_000479 NC(=O)Nc1ccc(cc1)/C(=C/c2ccncc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F18 compound treatment 0.265 0.0506 0.72 0.251 0.0357 0.6 0.9349 0.9956 3062550 Maybridge4_000480 CN(C)C(=S)SCc1c(C)c(C)c(C)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F19 compound treatment 0.274 0.0596 0.85 0.212 -0.00331 -0.06 0.5631 0.6596 3178628 Maybridge4_000481 COc1ccc(cc1)n2c(CC#N)nnc2SCc3c(C)c(C)c(C)c(C)c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F20 compound treatment 0.238 0.0236 0.34 0.264 0.0487 0.82 0.8161 0.9233 3178629 Maybridge4_000482 CC1(C)ON(C(=N1)NC(=O)NC(=O)c2ccccc2Cl)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F21 compound treatment 0.247 0.0326 0.47 0.235 0.0197 0.33 0.563 0.9859 3062551 Maybridge4_000483 O=S(=O)(/N=C/1\NCC2CCCC2N1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F22 compound treatment 0.193 -0.0214 -0.31 0.217 0.00169 0.03 -0.1968 -0.6391 3178630 Maybridge4_000484 CC(CO)(CO)NC(=S)Nc1ccc(F)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F23 mock treatment 0.226 0.0116 0.17 0.231 0.0157 0.26 0.3031 0.9749 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 F24 mock treatment 0.197 -0.0174 -0.25 0.221 0.00569 0.1 -0.1089 -0.4076 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G01 compound treatment 0.245 0.0306 0.44 0.226 0.0107 0.18 0.436 0.9226 1441207 Maybridge4_000485 CC(C)(C)c1cc2[nH]c(=N)[nH]c(=N)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G02 compound treatment 0.247 0.0326 0.47 0.219 0.00369 0.06 0.3731 0.7941 1390371 Maybridge4_000486 O=c1c(Cc2ccccc2OCc3ccccc3)coc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G03 compound treatment 0.237 0.0226 0.32 0.224 0.00869 0.15 0.3313 0.9355 3062552 Maybridge4_000487 COc1ccccc1C2OC(=O)C[C@H]2C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G04 compound treatment 0.247 0.0326 0.47 0.243 0.0277 0.46 0.6579 1.0 1630105 Maybridge4_000488 Brc1ccc(cc1)C(=O)c2cc3OCCCOc3cc2Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G05 compound treatment 0.253 0.0386 0.55 0.229 0.0137 0.23 0.5525 0.9246 1255736 Maybridge4_000489 COc1cc(OC)nc(NCC(NC(=O)c2ccccc2)C(=O)N)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G06 compound treatment 0.259 0.0446 0.64 0.265 0.0497 0.83 1.0404 0.9912 1191076 Maybridge4_000490 CNc1cc(=O)n(c2ccccc2)c(=O)n1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G07 compound treatment 0.277 0.0626 0.89 0.309 0.0937 1.57 1.7447 0.9643 1024944 Maybridge4_000491 CCOC(=O)c1oc(C(=O)OCC)c(O)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G08 compound treatment 0.307 0.0926 1.32 0.268 0.0527 0.88 1.5615 0.9807 3062592 Maybridge4_000492 CC(C)(C)c1ccc2cc(C#N)c(C#N)cc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G09 compound treatment 0.301 0.0866 1.24 0.262 0.0467 0.78 1.4296 0.9756 3062593 Maybridge4_000493 O=C1N(CCCCN2C(=O)c3ccccc3S2(=O)=O)S(=O)(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G10 compound treatment 0.257 0.0426 0.61 0.29 0.0747 1.25 1.3169 0.945 3062594 Maybridge4_000494 Cc1ccc(NC(=O)N(C2=NCC(C)(C)S2)c3ccc(F)c(Cl)c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G11 compound treatment 0.22 0.00556 0.08 0.302 0.0867 1.45 1.0851 0.7447 1051499 Maybridge4_000495 CC(O)c1ccc2ccccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G12 compound treatment 0.248 0.0336 0.48 0.256 0.0407 0.68 0.8223 0.9851 1332464 Maybridge4_000496 OCCOC(=O)c1cccc2C(=O)c3ccccc3-c21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G13 compound treatment 0.275 0.0606 0.87 0.312 0.0967 1.62 1.76 0.9568 1397918 Maybridge4_000497 CCCN(CCC)C(=O)c1cccc2C(=O)c3ccccc3-c21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G14 compound treatment 0.249 0.0346 0.49 0.252 0.0367 0.62 0.785 0.9941 3178631 Maybridge4_000498 CC(C)(C)C(=O)OC[C@H]1O[C@H](C[C@@H]1OC(=O)C(C)(C)C)n2cnc3c(N)ncnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G15 compound treatment 0.264 0.0496 0.71 0.264 0.0487 0.82 1.0791 0.9975 3062595 Maybridge4_000499 O=C(OC1=CC(=O)c2cccc3cccc1c23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G16 compound treatment 0.245 0.0306 0.44 0.237 0.0217 0.36 0.5665 0.9959 1645132 Maybridge4_000500 O=C(NC1CCN(Cc2cccc3ccccc23)CC1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G17 compound treatment 0.203 -0.0114 -0.16 0.255 0.0397 0.67 0.3553 0.518 1430296 Maybridge4_000501 OCc1cccc2cccc(S(=O)c3cccc4cccc(C(=O)O)c34)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G18 compound treatment 0.241 0.0266 0.38 0.257 0.0417 0.7 0.7634 0.9588 1284168 Maybridge4_000502 Brc1ccc(Cc2csc3ccccc3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G19 compound treatment 0.235 0.0206 0.29 0.212 -0.00331 -0.06 0.1687 0.5635 3178632 Maybridge4_000503 FC(F)(F)Oc1ccccc1NC(=O)CC(=O)Nc2ccccc2OC(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G20 compound treatment 0.214 -4.38E-4 -0.01 0.196 -0.0193 -0.32 -0.2336 -0.7206 1186920 Maybridge4_000504 NNC(=O)C1(CCCC2CCC1)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G21 compound treatment 0.216 0.00156 0.02 0.202 -0.0133 -0.22 -0.1422 -0.6332 3062596 Maybridge4_000505 FC1(C(=O)Nc2c(Cl)c(Cl)ccc2C1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G22 compound treatment 0.21 -0.00444 -0.06 0.22 0.00469 0.08 0.0107 0.1063 3178633 Maybridge4_000506 CC(C)(C)OC(=O)Cn1ccc(=O)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G23 mock treatment 0.191 -0.0234 -0.34 0.212 -0.00331 -0.06 -0.2764 -0.8133 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 G24 mock treatment 0.214 -4.38E-4 -0.01 0.202 -0.0133 -0.22 -0.1624 -0.7266 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H01 compound treatment 0.05 -0.164 -2.35 0.051 -0.164 -2.76 -3.6132 -0.9969 3178634 Maybridge4_000507 O/N=C(/C1CC2CCC1CC2)\c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H02 compound treatment 0.213 -0.00144 -0.02 0.221 0.00569 0.1 0.053 0.5424 1138209 Maybridge4_000508 N1C(c2cccn2-c3ccccc13)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H03 compound treatment 0.24 0.0256 0.37 0.252 0.0367 0.62 0.694 0.969 1326325 Maybridge4_000509 Cc1c(C)c(C)c(CN2C(=O)c3ccccc3C2=O)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H04 compound treatment 0.282 0.0676 0.97 0.248 0.0327 0.55 1.0713 0.964 3062597 Maybridge4_000510 Cc1c(cc2c(c1n3cccc3)C(C)(C)CC2(C)C)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H05 compound treatment 0.272 0.0576 0.82 0.301 0.0857 1.44 1.5991 0.965 3178635 Maybridge4_000511 Fc1ccc(cc1)C(=O)CSc2nsc(SCC(=O)c3ccc(F)cc3)c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H06 compound treatment 0.047 -0.167 -2.39 0.047 -0.168 -2.82 -3.691 -0.9966 3178636 Maybridge4_000512 CC(C)C1CCC(C)CC1NC(=S)Nc2cccc(F)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H07 compound treatment 0.273 0.0586 0.84 0.25 0.0347 0.58 1.004 0.9842 1248377 Maybridge4_000513 CC1CCCCN1C(=S)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H08 compound treatment 0.27 0.0556 0.79 0.258 0.0427 0.72 1.0686 0.9987 3178637 Maybridge4_000514 COc1cccc(OC)c1C(=O)Nc2cc(c(Cl)cc2OC)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H09 compound treatment 0.272 0.0576 0.82 0.306 0.0907 1.52 1.6585 0.9584 1054040 Maybridge4_000515 CC(C)C1=NNC(=O)C1(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H10 compound treatment 0.313 0.0986 1.41 0.302 0.0867 1.45 2.0257 0.9999 1253333 Maybridge4_000516 Nc1nc2c(nnn2c3ccccc13)C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H11 compound treatment 0.248 0.0336 0.48 0.282 0.0667 1.12 1.1309 0.9286 1700266 Maybridge4_000517 COc1ccc(CCNC(=S)NCCc2ccccc2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H12 compound treatment 0.259 0.0446 0.64 0.286 0.0707 1.19 1.2896 0.9576 3178638 Maybridge4_000518 O/N=C(\C#N)/C(=O)c1ccco1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H13 compound treatment 0.279 0.0646 0.92 0.28 0.0647 1.09 1.4207 0.9968 1672819 Maybridge4_000519 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H14 compound treatment 0.279 0.0646 0.92 0.286 0.0707 1.19 1.4919 0.9923 3178639 Maybridge4_000520 Fc1cc(F)c(NC(=S)N2CCOCC2)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H15 compound treatment 0.328 0.114 1.62 0.282 0.0667 1.12 1.9401 0.9835 1546700 Maybridge4_000521 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)NN)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H16 compound treatment 0.298 0.0836 1.2 0.283 0.0677 1.14 1.6485 0.9997 3062598 Maybridge4_000522 Fc1cccc(NCc2cccs2)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H17 compound treatment 0.289 0.0746 1.07 0.297 0.0817 1.37 1.7236 0.9923 3178640 Maybridge4_000523 NC(=O)Nc1ccc(cc1)/C(=C/c2ccc(Cl)c(Cl)c2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H18 compound treatment 0.274 0.0596 0.85 0.282 0.0667 1.12 1.3939 0.9909 3062599 Maybridge4_000524 CN(C)C(=S)SCC(=O)c1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H19 compound treatment 0.06 -0.154 -2.21 0.055 -0.16 -2.69 -3.4646 -0.9952 1221296 Maybridge4_000525 Cc1cc(C)c2-c3[nH]c(nc3C(C)(C)Cc2c1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H20 compound treatment 0.232 0.0176 0.25 0.224 0.00869 0.15 0.2807 0.9665 1556252 Maybridge4_000526 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H21 compound treatment 0.253 0.0386 0.55 0.238 0.0227 0.38 0.6593 0.9836 3062600 Maybridge4_000527 CC1CN/C(=N/S(=O)(=O)c2ccccc2)/N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H22 compound treatment 0.188 -0.0264 -0.38 0.209 -0.00631 -0.11 -0.3423 -0.8717 1621149 Maybridge4_000528 CC1CC(C)CN(C1)c2ccc(NS(=O)(=O)c3ccccc3)cc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H23 mock treatment 0.215 5.62E-4 0.01 0.198 -0.0173 -0.29 -0.1998 -0.6873 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 H24 mock treatment 0.192 -0.0224 -0.32 0.191 -0.0243 -0.41 -0.5155 -0.9929 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I01 compound treatment 0.24 0.0256 0.37 0.238 0.0227 0.38 0.5278 0.9998 3062601 Maybridge4_000529 Cc1ccc(Oc2ncc(cc2Cl)C(F)(F)F)c3CCCc31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I02 compound treatment 0.195 -0.0194 -0.28 0.204 -0.0113 -0.19 -0.3309 -0.9827 3178641 Maybridge4_000530 CCOC(=O)CSc1nnc(S)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I03 compound treatment 0.272 0.0576 0.82 0.23 0.0147 0.25 0.7565 0.8802 3178642 Maybridge4_000531 Cc1nc(cs1)c2cc(C#N)c(SCCNS(=O)(=O)c3ccc(cc3)C(C)(C)C)nc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I04 compound treatment 0.22 0.00556 0.08 0.26 0.0447 0.75 0.5866 0.7778 1202864 Maybridge4_000532 Cc1ccc(cc1)C(=O)C2C(=O)N(C(=O)N(C2=O)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I05 compound treatment 0.245 0.0306 0.44 0.252 0.0367 0.62 0.7445 0.9859 1219965 Maybridge4_000533 Cc1nn(nc1C(=O)ON2C(=O)C3C4OC(C=C4)C3C2=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I06 compound treatment 0.282 0.0676 0.97 0.297 0.0817 1.37 1.6528 0.9853 3062602 Maybridge4_000534 COc1ccc(/C=C\2/C(Oc3ccccc3C2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I07 compound treatment 0.263 0.0486 0.69 0.276 0.0607 1.02 1.2114 0.9826 1277364 Maybridge4_000535 CCOC(=O)c1c(O)c(O)c(C(=O)OCC)n1c2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I08 compound treatment 0.27 0.0556 0.79 0.236 0.0207 0.35 0.8075 0.9311 1178381 Maybridge4_000536 Fc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I09 compound treatment 0.275 0.0606 0.87 0.265 0.0497 0.83 1.2022 0.9998 1497959 Maybridge4_000537 CC(C)C1CCC(C)CC1NC(=O)c2cccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I10 compound treatment 0.275 0.0606 0.87 0.272 0.0567 0.95 1.2853 0.9989 1039563 Maybridge4_000538 Clc1ccc2oc(cc(=O)c2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I11 compound treatment 0.288 0.0736 1.05 0.323 0.108 1.81 2.0221 0.9669 1035419 Maybridge4_000539 O=C(c1ccccc1)c2ccc(cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I12 compound treatment 0.273 0.0586 0.84 0.286 0.0707 1.19 1.4312 0.9855 3178724 Maybridge4_000540 Sc1nn(c2ccc(Cl)cc2)c(=S)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I13 compound treatment 0.292 0.0776 1.11 0.245 0.0297 0.5 1.1368 0.9347 1060199 Maybridge4_000541 CNC(=O)c1cccc2C(=O)c3ccccc3-c21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I14 compound treatment 0.288 0.0736 1.05 0.265 0.0497 0.83 1.3337 0.9934 3178725 Maybridge4_000542 NNC(=O)c1cc(n[nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I15 compound treatment 0.275 0.0606 0.87 0.247 0.0317 0.53 0.9886 0.9726 1005720 Maybridge4_000543 CN(C)c1ccc(Cc2ccc(cc2)N(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I16 compound treatment 0.165 -0.0494 -0.71 0.183 -0.0323 -0.54 -0.8835 -0.9914 1587057 Maybridge4_000544 COc1ccccc1C2CCN(Cc3cccc4ccccc34)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I17 compound treatment 0.283 0.0686 0.98 0.261 0.0457 0.77 1.2357 0.9926 2075442 Maybridge4_000545 CN1[S+](c2ccccc2C(=O)O)c3cccc4cccc(C1=O)c34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I18 compound treatment 0.23 0.0156 0.22 0.232 0.0167 0.28 0.3555 0.9935 3178726 Maybridge4_000546 Nc1ccccc1SC(CC(=O)c2ccc(Br)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I19 compound treatment 0.098 -0.116 -1.67 0.268 0.0527 0.88 -0.5524 -0.2929 1287387 Maybridge4_000547 OCC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I20 compound treatment 0.222 0.00756 0.11 0.198 -0.0173 -0.29 -0.129 -0.416 1441014 Maybridge4_000548 OC(=O)C1(CCCC2(CCC1)C(=O)O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I21 compound treatment 0.142 -0.0724 -1.04 0.187 -0.0283 -0.48 -1.0687 -0.9375 1343250 Maybridge4_000549 O=C1C(C2c3ccccc3Oc4ccccc24)C(=O)c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I22 compound treatment 0.138 -0.0764 -1.09 0.173 -0.0423 -0.71 -1.2753 -0.9782 3062641 Maybridge4_000550 OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I23 mock treatment 0.201 -0.0134 -0.19 0.217 0.00169 0.03 -0.1159 -0.5965 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 I24 mock treatment 0.215 5.62E-4 0.01 0.198 -0.0173 -0.29 -0.1998 -0.6873 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J01 compound treatment 0.219 0.00456 0.07 0.238 0.0227 0.38 0.3154 0.8164 3062642 Maybridge4_000551 COC(=O)C1CCC(=O)C(C1)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J02 compound treatment 0.216 0.00156 0.02 0.231 0.0157 0.26 0.202 0.7644 1601179 Maybridge4_000552 Oc1ccc2ccccc2c1C3Nc4ccccc4-n5cccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J03 compound treatment 0.234 0.0196 0.28 0.238 0.0227 0.38 0.4671 0.9885 3062643 Maybridge4_000553 Cc1c(C)c(C)c(CN2CCCCC2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J04 compound treatment 0.158 -0.0564 -0.81 0.121 -0.0943 -1.58 -1.6901 -0.9512 3062644 Maybridge4_000554 CC(=O)Nc1s/c(=N\c2ccc(C)c(C)c2)/n(C(=O)C)c1c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J05 compound treatment 0.288 0.0736 1.05 0.258 0.0427 0.72 1.2506 0.9825 1342204 Maybridge4_000555 O=S(=O)(N1CCCCC1)c2ccc(NC(=S)Nc3ccc4OCOc4c3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J06 compound treatment 0.224 0.00956 0.14 0.195 -0.0203 -0.34 -0.1444 -0.393 3062645 Maybridge4_000556 Clc1ccc(Cl)c(NC(=S)NC(=N)c2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J07 compound treatment 0.241 0.0266 0.38 0.236 0.0207 0.35 0.5142 0.999 3178727 Maybridge4_000557 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(CC3C(=O)Nc4ccccc34)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J08 compound treatment 0.279 0.0646 0.92 0.261 0.0457 0.77 1.1952 0.9957 3178728 Maybridge4_000558 CN1CCC2(C(C1)N=NN2c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J09 compound treatment 0.225 0.0106 0.15 0.305 0.0897 1.51 1.1713 0.7742 3062646 Maybridge4_000559 Cc1cc(C)c(C(=O)Nc2cccc(c2)C(F)(F)F)c3CC(C)(C)C(=O)c31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J10 compound treatment 0.287 0.0726 1.04 0.275 0.0597 1.0 1.4423 0.9998 1734956 Maybridge4_000560 Nc1nc2c(nnn2c3ccccc13)c4ccc(Br)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J11 compound treatment 0.16 -0.0544 -0.78 0.292 0.0767 1.29 0.3595 0.239 3178729 Maybridge4_000561 Cc1c(C)c(C)c(C(O)c2ccccc2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J12 compound treatment 0.266 0.0516 0.74 0.293 0.0777 1.3 1.4435 0.9636 3178730 Maybridge4_000562 COc1ccc(cc1)c2c(C#N)nnn2c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J13 compound treatment 0.228 0.0136 0.19 0.259 0.0437 0.73 0.6557 0.8644 1646858 Maybridge4_000563 CCN1C(C(CCC1=O)C(=O)O)c2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J14 compound treatment 0.326 0.112 1.6 0.298 0.0827 1.39 2.1097 0.9976 1299644 Maybridge4_000564 Fc1cccc(NCCc2ccccn2)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J15 compound treatment 0.328 0.114 1.62 0.281 0.0657 1.1 1.9282 0.9822 3062647 Maybridge4_000565 CCOC(=S)SCc1c(C)c(C)c(C)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J16 compound treatment 0.274 0.0596 0.85 0.25 0.0347 0.58 1.0141 0.9828 1536926 Maybridge4_000566 O=C(CC#N)NCc1cccs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J17 compound treatment 0.305 0.0906 1.3 0.315 0.0997 1.67 2.0991 0.992 3178731 Maybridge4_000567 Cc1onc(c1NC(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J18 compound treatment 0.299 0.0846 1.21 0.261 0.0457 0.77 1.3975 0.9758 1727398 Maybridge4_000568 CCc1cccc(C(C)C)c1NS(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J19 compound treatment 0.285 0.0706 1.01 0.254 0.0387 0.65 1.1728 0.9772 3062649 Maybridge4_000569 Nn1c(nc2ccccc2c1=O)C(=O)NCc3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J20 compound treatment 0.237 0.0226 0.32 0.234 0.0187 0.31 0.45 0.9999 3178732 Maybridge4_000570 CC1CCCCN1CCCNC(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J21 compound treatment 0.222 0.00756 0.11 0.234 0.0187 0.31 0.2983 0.899 3062650 Maybridge4_000571 Clc1ccc(SCc2ccc(C#N)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J22 compound treatment 0.202 -0.0124 -0.18 0.244 0.0287 0.48 0.2147 0.4182 3178733 Maybridge4_000572 CC1CN(CC(C)O1)c2ccc(NC(=O)c3ccco3)cc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J23 mock treatment 0.246 0.0316 0.45 0.258 0.0427 0.72 0.8258 0.9752 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 J24 mock treatment 0.186 -0.0284 -0.41 0.216 6.88E-4 0.01 -0.2795 -0.6868 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K01 compound treatment 0.24 0.0256 0.37 0.255 0.0397 0.67 0.7296 0.9601 1258100 Maybridge4_000573 OC(=O)C1CC1C(=O)Nc2ccc(Oc3ccc(Cl)cc3C4CCCCC4)nc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K02 compound treatment 0.21 -0.00444 -0.06 0.208 -0.00731 -0.12 -0.1317 -0.9529 3062651 Maybridge4_000574 CCOC(=O)CCSc1nnc(S)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K03 compound treatment 0.289 0.0746 1.07 0.233 0.0177 0.3 0.9641 0.8708 1465836 Maybridge4_000575 Fc1ccc(COc2ccc(cc2)C(=O)CSc3ccccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K04 compound treatment 0.262 0.0476 0.68 0.236 0.0207 0.35 0.7266 0.9513 1182542 Maybridge4_000576 CC1(CC2(C)CC3(C)C1)CC(C2)(C3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K05 compound treatment 0.309 0.0946 1.35 0.296 0.0807 1.35 1.914 1.0 3178734 Maybridge4_000577 OC1CCCCCCCCCCC1CCC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K06 compound treatment 0.238 0.0236 0.34 0.242 0.0267 0.45 0.555 0.9902 3062652 Maybridge4_000578 CC(C)CCNC(=O)Oc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K07 compound treatment 0.258 0.0436 0.62 0.252 0.0367 0.62 0.876 1.0 3178735 Maybridge4_000579 COc1ccc(OC)c2c(=O)cc(oc12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K08 compound treatment 0.26 0.0456 0.65 0.229 0.0137 0.23 0.6233 0.902 1674875 Maybridge4_000580 COc1ccccc1C2CCN(CC2)C(=O)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K09 compound treatment 0.216 0.00156 0.02 0.234 0.0187 0.31 0.2376 0.7556 3178736 Maybridge4_000581 CC1(C)C2CCC1(C)C(C2)NC(=O)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K10 compound treatment 0.296 0.0816 1.17 0.301 0.0857 1.44 1.8419 0.9946 1672849 Maybridge4_000582 Cc1onc(c1C(=O)N2CC(C2)Oc3ccc(Cl)cc3)c4c(F)cccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K11 compound treatment 0.27 0.0556 0.79 0.277 0.0617 1.04 1.2941 0.9915 3062653 Maybridge4_000583 Cc1cc(n[nH]c1=O)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K12 compound treatment 0.233 0.0186 0.27 0.277 0.0617 1.04 0.9199 0.8606 3062654 Maybridge4_000584 Sc1nc(c2ccccc2)n(n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K13 compound treatment 0.202 -0.0124 -0.18 0.251 0.0357 0.6 0.2977 0.4765 1267527 Maybridge4_000585 CC(C)CCNC(=O)c1cccc2C(=O)c3ccccc3-c21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K14 compound treatment 0.283 0.0686 0.98 0.24 0.0247 0.41 0.9865 0.9266 3062655 Maybridge4_000586 O=C1C(CCCC1c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K15 compound treatment 0.24 0.0256 0.37 0.234 0.0187 0.31 0.4803 0.9971 3178737 Maybridge4_000587 Cc1c(cnc2ccccc12)c3nnnn3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K16 compound treatment 0.254 0.0396 0.57 0.263 0.0477 0.8 0.9661 0.9856 1175626 Maybridge4_000588 Cc1ccc(cc1)C(=O)OC2CN3CCC2CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K17 compound treatment 0.256 0.0416 0.59 0.223 0.00769 0.13 0.5116 0.841 3178738 Maybridge4_000589 CN1[S+](c2ccccc2C1=O)c3cccc4cccc(C(=O)O)c34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K18 compound treatment 0.213 -0.00144 -0.02 0.213 -0.00231 -0.04 -0.042 -0.9559 3178739 Maybridge4_000590 CC1(C)C2CCC1(C)c3nn(c(c23)C(F)(F)F)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K19 compound treatment 0.221 0.00656 0.09 0.233 0.0177 0.3 0.2763 0.8874 1361703 Maybridge4_000591 CCOC(Cn1c2ccccc2c3ccccc13)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K20 compound treatment 0.24 0.0256 0.37 0.233 0.0177 0.3 0.4685 0.9947 1031191 Maybridge4_000592 OC(=O)C1C(C2CCC1C2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K21 compound treatment 0.268 0.0536 0.77 0.218 0.00269 0.05 0.5736 0.7474 1224135 Maybridge4_000593 Cn1c(nc2ccccc12)C(C#N)C(=O)c3ccccc3I 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K22 compound treatment 0.161 -0.0534 -0.76 0.177 -0.0383 -0.64 -0.9952 -0.9963 1062658 Maybridge4_000594 CCOC(=O)C1C(C2c3ccccc3C1c4ccccc24)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K23 mock treatment 0.208 -0.00644 -0.09 0.215 -3.12E-4 -0.01 -0.0688 -0.7462 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 K24 mock treatment 0.231 0.0166 0.24 0.191 -0.0243 -0.41 -0.121 -0.2565 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L01 compound treatment 0.199 -0.0154 -0.22 0.24 0.0247 0.41 0.1369 0.2915 3062656 Maybridge4_000595 CCCCN(C(C)C)S(=O)(=O)c1ccc(C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L02 compound treatment 0.217 0.00256 0.04 0.214 -0.00131 -0.02 0.0103 0.2418 3178740 Maybridge4_000596 FC(F)(F)c1cccc(c1)/C(=C/C=C/c2ccccc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L03 compound treatment 0.233 0.0186 0.27 0.235 0.0197 0.33 0.4214 0.9941 3062657 Maybridge4_000597 O=C1NC(=O)C(=CC2CCC=CC2)C(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L04 compound treatment 0.245 0.0306 0.44 0.257 0.0417 0.7 0.8039 0.9744 1174872 Maybridge4_000598 Fc1cccc(F)c1C(=O)Nc2cccc(NC(=O)c3c(F)cccc3F)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L05 compound treatment 0.203 -0.0114 -0.16 0.217 0.00169 0.03 -0.0957 -0.5761 3178741 Maybridge4_000599 COc1ccc(CC/N=C/c2ccc3OCOc3c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L06 compound treatment 0.24 0.0256 0.37 0.261 0.0457 0.77 0.8008 0.9426 3062658 Maybridge4_000600 FC(F)(F)c1cc(C#CCN2CCCCC2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L07 compound treatment 0.263 0.0486 0.69 0.243 0.0277 0.46 0.8198 0.9809 3178820 Maybridge4_000601 CC(C)NC(=S)N1CCCN2C1c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L08 compound treatment 0.258 0.0436 0.62 0.252 0.0367 0.62 0.876 1.0 3062659 Maybridge4_000602 FC(F)(F)c1cccc(c1C(=O)OCC(=O)c2ccc(Cl)cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L09 compound treatment 0.27 0.0556 0.79 0.312 0.0967 1.62 1.7095 0.946 1236762 Maybridge4_000603 S=C(Nc1ccccc1)Nc2ccccc2n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L10 compound treatment 0.245 0.0306 0.44 0.242 0.0267 0.45 0.6258 0.9999 3062660 Maybridge4_000604 COc1ccc(OC)c(c1)S(=O)(=O)c2ccc(Br)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L11 compound treatment 0.27 0.0556 0.79 0.235 0.0197 0.33 0.7956 0.9244 1138158 Maybridge4_000605 COc1ccc(OCCC(=O)NN)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L12 compound treatment 0.253 0.0386 0.55 0.293 0.0777 1.3 1.312 0.9267 3062661 Maybridge4_000606 CN(C)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L13 compound treatment 0.224 0.00956 0.14 0.273 0.0577 0.97 0.7814 0.7991 3178821 Maybridge4_000607 OC(Cc1ccccc1)(c2ccccc2)c3ccccc3/N=C/c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L14 compound treatment 0.075 -0.139 -1.99 0.145 -0.0703 -1.18 -2.2448 -0.9686 3178822 Maybridge4_000608 Fc1cccc(N(Cc2cccnc2)C(=S)Nc3ccc(Cl)c(Cl)c3)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L15 compound treatment 0.251 0.0366 0.52 0.278 0.0627 1.05 1.1138 0.9479 3062708 Maybridge4_000609 Cc1c(C)c(C)c(CSc2ccccn2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L16 compound treatment 0.211 -0.00344 -0.05 0.293 0.0777 1.3 0.8872 0.68 3062709 Maybridge4_000610 CC(C)NC(=O)NCc1c(F)cccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L17 compound treatment 0.29 0.0756 1.08 0.243 0.0277 0.46 1.0929 0.9289 3062710 Maybridge4_000611 Cc1c(C)c(C)c(C(=O)/C=N/N)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L18 compound treatment 0.262 0.0476 0.68 0.237 0.0217 0.36 0.7384 0.9571 3062711 Maybridge4_000612 CCc1cccc(C(C)C)c1NC(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L19 compound treatment 0.242 0.0276 0.39 0.242 0.0267 0.45 0.5955 0.998 3062712 Maybridge4_000613 COc1ccc(NC(=S)NCCCC2C=NN=C2O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L20 compound treatment 0.3 0.0856 1.22 0.277 0.0617 1.04 1.5975 0.9965 3062713 Maybridge4_000614 CC(C)(C)C1=C(C#N)C(C(=C(NC(=O)NC(=O)c2c(F)cccc2Cl)O1)C#N)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L21 compound treatment 0.289 0.0746 1.07 0.295 0.0797 1.34 1.6999 0.9937 1309274 Maybridge4_000615 Cc1cc(C)c(C(=O)Nc2ccc(C)c(C)c2)c(CC(C)(C)C(=O)O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L22 compound treatment 0.13 -0.0844 -1.21 0.139 -0.0763 -1.28 -1.7597 -0.9996 3178823 Maybridge4_000616 OCC(CO)(CO)NC(=S)Nc1cc(Cl)cc(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L23 mock treatment 0.194 -0.0204 -0.29 0.248 0.0327 0.55 0.1812 0.2915 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 L24 mock treatment 0.226 0.0116 0.17 0.207 -0.00831 -0.14 0.0183 0.0845 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M01 compound treatment 0.27 0.0556 0.79 0.242 0.0267 0.45 0.8787 0.9632 1443995 Maybridge4_000617 CCCc1ccc(Oc2ccc(NC(=O)C3CC3C(=O)O)cn2)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M02 compound treatment 0.251 0.0366 0.52 0.251 0.0357 0.6 0.7933 0.9977 2105374 Maybridge4_000618 Oc1ccc(cc1)C(C#N)N2CCN(CC2)C(C#N)c3ccc(O)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M03 compound treatment 0.205 -0.00944 -0.13 0.258 0.0427 0.72 0.4112 0.564 1235908 Maybridge4_000619 Cc1nc(cs1)c2cc(C#N)c(SCCC(=O)OC(C)(C)C)nc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M04 compound treatment 0.278 0.0636 0.91 0.268 0.0527 0.88 1.2682 0.9999 1332220 Maybridge4_000620 COc1ccc(cc1)C(=O)NC2(CC3CC4CC(C3)C2)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M05 compound treatment 0.22 0.00556 0.08 0.26 0.0447 0.75 0.5866 0.7778 3178824 Maybridge4_000621 CN1C2CCC1CC(C2)NC(=O)Cc3ccccc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M06 compound treatment 0.256 0.0416 0.59 0.228 0.0127 0.21 0.5709 0.9041 3062715 Maybridge4_000622 CCNC(=O)Oc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M07 compound treatment 0.246 0.0316 0.45 0.239 0.0237 0.4 0.6004 0.998 3062716 Maybridge4_000623 CN(C)/C=C/C(=O)c1c(O)cc(C)oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M08 compound treatment 0.249 0.0346 0.49 0.26 0.0447 0.75 0.8799 0.9795 1250275 Maybridge4_000624 COc1ccccc1C2CCN(CC2)C(=O)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M09 compound treatment 0.252 0.0376 0.54 0.218 0.00269 0.05 0.4118 0.7638 1731106 Maybridge4_000625 COc1ccc(Br)cc1COC(=O)C2c3ccccc3Oc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M10 compound treatment 0.274 0.0596 0.85 0.254 0.0387 0.65 1.0616 0.991 1917572 Maybridge4_000626 CCOc1ccc2[nH]c(SCc3c(F)c(F)c(F)c(F)c3F)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M11 compound treatment 0.275 0.0606 0.87 0.272 0.0567 0.95 1.2853 0.9989 1003070 Maybridge4_000627 Cc1ccc(cc1)S(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M12 compound treatment 0.161 -0.0534 -0.76 0.166 -0.0493 -0.83 -1.1257 -0.9992 3062717 Maybridge4_000628 CSc1nc2c(=S)[nH]c(=S)[nH]c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M13 compound treatment 0.253 0.0386 0.55 0.221 0.00569 0.1 0.4575 0.8173 3062718 Maybridge4_000629 O/N=C(/C(=N/O)/c1ccccc1)\c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M14 compound treatment 0.243 0.0286 0.41 0.273 0.0577 0.97 0.9735 0.9264 1781230 Maybridge4_000630 CCOC(=O)CNc1n[nH]c(=O)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M15 compound treatment 0.178 -0.0364 -0.52 0.228 0.0127 0.21 -0.218 -0.3871 3062719 Maybridge4_000631 Cc1cc(C)nc(S/C=C/C(=O)c2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M16 compound treatment 0.266 0.0516 0.74 0.265 0.0497 0.83 1.1112 0.9981 1718236 Maybridge4_000632 Cn1c(=O)cc(N2CCOCC2)c3c(=O)n(c4ccccc4)c(=O)n(c5ccccc5)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M17 compound treatment 0.284 0.0696 0.99 0.211 -0.00431 -0.07 0.6524 0.6539 3178825 Maybridge4_000633 CC(=O)NC1=NN(C(N1C(=O)C)c2cccc3ccccc23)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M18 compound treatment 0.307 0.0926 1.32 0.277 0.0617 1.04 1.6683 0.9926 1286292 Maybridge4_000634 O=C(NC(C(=O)c1ccccc1)n2cnccc2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M19 compound treatment 0.283 0.0686 0.98 0.215 -3.12E-4 -0.01 0.6897 0.7033 1171458 Maybridge4_000635 OC(COCc1ccccc1)Cn2c3ccccc3c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M20 compound treatment 0.205 -0.00944 -0.13 0.227 0.0117 0.2 0.0433 0.1817 3062720 Maybridge4_000636 C/S(=N\S(=O)(=O)c1ccc(C)cc1)/c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M21 compound treatment 0.217 0.00256 0.04 0.203 -0.0123 -0.21 -0.1202 -0.5728 1311339 Maybridge4_000637 O=C(C(C#N)c1nc2ccccc2[nH]1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M22 compound treatment 0.221 0.00656 0.09 0.224 0.00869 0.15 0.1695 0.9773 1645478 Maybridge4_000638 COC(=O)C1C([C@H]2c3ccccc3[C@@H]1c4ccccc24)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M23 mock treatment 0.186 -0.0284 -0.41 0.206 -0.00931 -0.16 -0.3981 -0.9137 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 M24 mock treatment 0.228 0.0136 0.19 0.218 0.00269 0.05 0.1691 0.8489 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N01 compound treatment 0.245 0.0306 0.44 0.241 0.0257 0.43 0.614 1.0 1273203 Maybridge4_000639 CN(C)CC1(CC(=O)O)CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N02 compound treatment 0.211 -0.00344 -0.05 0.242 0.0267 0.45 0.282 0.6257 3178826 Maybridge4_000640 NN/C(=N/S(=O)(=O)c1ccccc1)/N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N03 compound treatment 0.215 5.62E-4 0.01 0.251 0.0357 0.6 0.4292 0.7165 3062722 Maybridge4_000641 O=C1NC(=O)C(=C/C=C/c2ccccc2)C(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N04 compound treatment 0.232 0.0176 0.25 0.227 0.0117 0.2 0.3163 0.9925 1678177 Maybridge4_000642 COc1cccc(OC)c1C(=O)Nc2ccccc2NC(=O)c3c(OC)cccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N05 compound treatment 0.244 0.0296 0.42 0.251 0.0357 0.6 0.7225 0.9855 1073885 Maybridge4_000643 CCOc1ccc(CCC(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N06 compound treatment 0.231 0.0166 0.24 0.219 0.00369 0.06 0.2113 0.8629 3178827 Maybridge4_000644 CS/C(=N\S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N07 compound treatment 0.228 0.0136 0.19 0.254 0.0387 0.65 0.5963 0.8799 3062723 Maybridge4_000645 Oc1noc(O)c1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N08 compound treatment 0.249 0.0346 0.49 0.247 0.0317 0.53 0.7256 0.9993 3062724 Maybridge4_000646 NC(=S)NC1CC2CC1C=C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N09 compound treatment 0.205 -0.00944 -0.13 0.238 0.0227 0.38 0.1738 0.4302 3178828 Maybridge4_000647 CCNc1cc(N)[n+](CC)c2[nH]nc(N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N10 compound treatment 0.216 0.00156 0.02 0.299 0.0837 1.4 1.009 0.7183 1512370 Maybridge4_000648 COc1ccc(cc1CN2CCOCC2)c3cc(c4ccccc4)c(nn3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N11 compound treatment 0.197 -0.0174 -0.25 0.227 0.0117 0.2 -0.0377 -0.1187 1288584 Maybridge4_000649 S=C(NC1CC2CC1C=C2)N(CCC#N)Cc3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N12 compound treatment 0.243 0.0286 0.41 0.224 0.00869 0.15 0.392 0.9036 3178829 Maybridge4_000650 CC(=O)NCc1c(F)cccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N13 compound treatment 0.245 0.0306 0.44 0.275 0.0597 1.0 1.0175 0.9309 1566685 Maybridge4_000651 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2cccc(SC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N14 compound treatment 0.247 0.0326 0.47 0.195 -0.0203 -0.34 0.0883 0.1529 3062725 Maybridge4_000652 Fc1cccc(Cl)c1CSc2ccccc2C3=NCCCN3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N15 compound treatment 0.198 -0.0164 -0.24 0.219 0.00369 0.06 -0.1225 -0.5038 3178830 Maybridge4_000653 Cc1c(C)c(C)c(CSC2=NCCS2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N16 compound treatment 0.215 5.62E-4 0.01 0.262 0.0467 0.78 0.5598 0.7143 3062726 Maybridge4_000654 Clc1cc(C[n+]2ccccc2)c3OCOCc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N17 compound treatment 0.211 -0.00344 -0.05 0.219 0.00369 0.06 0.009 0.1138 3062727 Maybridge4_000655 Cn1c(S)nnc1CC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N18 compound treatment 0.231 0.0166 0.24 0.216 6.88E-4 0.01 0.1757 0.7407 3178831 Maybridge4_000656 CC1CC(C)CN(C1)S(=O)(=O)c2c(C)c(C)c(C)c(C)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N19 compound treatment 0.283 0.0686 0.98 0.231 0.0157 0.26 0.8796 0.8663 3178832 Maybridge4_000657 N#Cc1cccc(CSc2nnc(SCc3cccc(C#N)c3)s2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N20 compound treatment 0.217 0.00256 0.04 0.22 0.00469 0.08 0.0815 0.9396 3062728 Maybridge4_000658 CC1(C)ON(C(=N1)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N21 compound treatment 0.257 0.0426 0.61 0.239 0.0237 0.4 0.7116 0.9787 3178833 Maybridge4_000659 CC1N=C(SCC#N)N2C(C)N=C(SCC#N)N12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N22 compound treatment 0.246 0.0316 0.45 0.226 0.0107 0.18 0.4461 0.9182 1490971 Maybridge4_000660 Nc1ccccc1C(=O)NCc2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N23 mock treatment 0.225 0.0106 0.15 0.217 0.00169 0.03 0.1269 0.8253 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 N24 mock treatment 0.206 -0.00844 -0.12 0.183 -0.0323 -0.54 -0.4688 -0.8438 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O01 compound treatment 0.257 0.0426 0.61 0.264 0.0487 0.82 1.0083 0.9895 3178834 Maybridge4_000661 COc1ccccc1C2OC(=O)C[C@H]2C(=O)Oc3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O02 compound treatment 0.222 0.00756 0.11 0.251 0.0357 0.6 0.5 0.8215 3178835 Maybridge4_000662 FC(F)(F)c1cc(NC(=S)NCCN2CCNC2=O)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O03 compound treatment 0.213 -0.00144 -0.02 0.279 0.0637 1.07 0.7413 0.6934 1251917 Maybridge4_000663 Cc1ccc(OC(C)(C)C(=O)Nc2ccc(Oc3ccc(F)cc3F)nc2)c4CCCc41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O04 compound treatment 0.242 0.0276 0.39 0.241 0.0257 0.43 0.5836 0.999 3178836 Maybridge4_000664 Cc1ccccc1NC2=NCC(C)(C)S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O05 compound treatment 0.276 0.0616 0.88 0.246 0.0307 0.52 0.9869 0.9674 1342095 Maybridge4_000665 NC(=O)C1c2ccccc2Oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O06 compound treatment 0.277 0.0626 0.89 0.252 0.0367 0.62 1.0682 0.9834 3178916 Maybridge4_000666 CC(C)(C)NC(=O)Oc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O07 compound treatment 0.205 -0.00944 -0.13 0.243 0.0277 0.46 0.2331 0.4818 1101019 Maybridge4_000667 CC(C)(C)c1cc(c2oc(cc(=O)c2c1)C(=O)O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O08 compound treatment 0.243 0.0286 0.41 0.249 0.0337 0.57 0.6887 0.9873 1485865 Maybridge4_000668 Clc1ccc(OC2CN(C2)C(=O)NCC=C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O09 compound treatment 0.199 -0.0154 -0.22 0.249 0.0337 0.57 0.2437 0.4014 3178917 Maybridge4_000669 O=C(Oc1ccc2ccccc2c1)C3c4ccccc4Oc5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O10 compound treatment 0.19 -0.0244 -0.35 0.2 -0.0153 -0.26 -0.4289 -0.9886 1074403 Maybridge4_000670 C1CCC(CC1)Nc2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O11 compound treatment 0.225 0.0106 0.15 0.209 -0.00631 -0.11 0.0319 0.1729 1171317 Maybridge4_000671 COc1cc(OC)cc(c1)C(C)(C)OC(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O12 compound treatment 0.221 0.00656 0.09 0.245 0.0297 0.5 0.4187 0.8258 1302360 Maybridge4_000672 OC(=O)Cc1cncc(Br)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O13 compound treatment 0.246 0.0316 0.45 0.23 0.0147 0.25 0.4935 0.9595 3063089 Maybridge4_000673 C/C(=N\O)/c1c(O)c2ccccc2n(C)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O14 compound treatment 0.225 0.0106 0.15 0.211 -0.00431 -0.07 0.0557 0.3322 1915396 Maybridge4_000674 CC1(C)OC2C(CO)OC(C2O1)n3cnc4c(=O)[nH]cnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O15 compound treatment 0.228 0.0136 0.19 0.245 0.0297 0.5 0.4895 0.9155 1665055 Maybridge4_000675 CC(=O)OCc1ccccc1Sc2ccccc2C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O16 compound treatment 0.204 -0.0104 -0.15 0.228 0.0127 0.21 0.045 0.1731 3063091 Maybridge4_000676 CN1C(=O)/C(=C\NCc2ccccc2)/C(=O)c3c1n(C)c(=O)n(C)c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O17 compound treatment 0.188 -0.0264 -0.38 0.252 0.0367 0.62 0.168 0.2325 3178918 Maybridge4_000677 COC(=O)c1cc(=O)nc2O[C@@H]3C(O)[C@@H](CO)OC3n21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O18 compound treatment 0.216 0.00156 0.02 0.209 -0.00631 -0.11 -0.0591 -0.5459 1458724 Maybridge4_000678 OC(=O)CCC1(CC2CC3CC(O)(C2)C1)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O19 compound treatment 0.232 0.0176 0.25 0.243 0.0277 0.46 0.5062 0.9583 3178919 Maybridge4_000679 CCn1c2ccc(Cl)cc2c3cc(Cl)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O20 compound treatment 0.185 -0.0294 -0.42 0.197 -0.0183 -0.31 -0.5151 -0.988 1547077 Maybridge4_000680 Cc1ccc(cc1)S(=O)(=O)N=S(Cc2ccccc2)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O21 compound treatment 0.229 0.0146 0.21 0.19 -0.0253 -0.42 -0.1531 -0.3236 3063093 Maybridge4_000681 CC(C)(C)c1ccc(=O)[nH]n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O22 compound treatment 0.236 0.0216 0.31 0.194 -0.0213 -0.36 -0.0349 -0.0738 3178920 Maybridge4_000682 Brc1ccc(NC(=O)N2NC(=O)[C@H]([C@@H]2c3ccccc3)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O23 mock treatment 0.206 -0.00844 -0.12 0.218 0.00269 0.05 -0.0534 -0.4148 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 O24 mock treatment 0.193 -0.0214 -0.31 0.21 -0.00531 -0.09 -0.2799 -0.8764 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P01 compound treatment 0.236 0.0216 0.31 0.219 0.00369 0.06 0.2619 0.8324 3063094 Maybridge4_000683 COC(=O)/C=C/c1cn(C2OCC(CO)C2O)c(=O)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P02 compound treatment 0.231 0.0166 0.24 0.236 0.0207 0.35 0.413 0.9826 3178921 Maybridge4_000684 NNC(=O)CS(=O)Cc1cccc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P03 compound treatment 0.227 0.0126 0.18 0.264 0.0487 0.82 0.7049 0.8425 3063095 Maybridge4_000685 O=C1NC(=O)C(=Cc2cccc3ccccc23)C(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P04 compound treatment 0.248 0.0336 0.48 0.275 0.0597 1.0 1.0478 0.9432 3178922 Maybridge4_000686 O/N=C/c1ccc(o1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P05 compound treatment 0.159 -0.0554 -0.79 0.157 -0.0583 -0.98 -1.2528 -0.9945 1352669 Maybridge4_000687 COc1cccc(NC(=S)NC(Cc2ccccc2)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P06 compound treatment 0.221 0.00656 0.09 0.21 -0.00531 -0.09 0.0033 0.0257 1145524 Maybridge4_000688 Clc1ccc(Cl)c(NC(=S)Nc2ccc(nc2)N3CCOCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P07 compound treatment 0.198 -0.0164 -0.24 0.232 0.0167 0.28 0.0318 0.0869 1152510 Maybridge4_000689 COc1ccc(CSC2=C(C#N)C(=O)NC3(CCCCC3)S2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P08 compound treatment 0.239 0.0246 0.35 0.247 0.0317 0.53 0.6245 0.9797 3063149 Maybridge4_000690 Clc1ccccc1NC(=O)CC2SC(=NC2=O)NC3CC4CC3C=C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P09 compound treatment 0.216 0.00156 0.02 0.225 0.00969 0.16 0.1308 0.7968 3178923 Maybridge4_000691 CCNc1cc(N)[n+](CC)c2[nH]nc(/N=C/c3cc(Cl)cc(Cl)c3O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P10 compound treatment 0.214 -4.38E-4 -0.01 0.23 0.0147 0.25 0.1699 0.6889 3063150 Maybridge4_000692 N/C(=N\O)/CN1CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P11 compound treatment 0.225 0.0106 0.15 0.208 -0.00731 -0.12 0.02 0.103 1138088 Maybridge4_000693 S=C(NC1CC2CC1C=C2)N(CCC#N)CC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P12 compound treatment 0.241 0.0266 0.38 0.263 0.0477 0.8 0.8346 0.942 3063152 Maybridge4_000694 Fc1cccc(Cl)c1CSC2=NCCN2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P13 compound treatment 0.229 0.0146 0.21 0.281 0.0657 1.1 0.9269 0.8261 1637772 Maybridge4_000695 Cc1onc(c1C(=O)N2CCCN3C2c4ccccc4C3=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P14 compound treatment 0.223 0.00856 0.12 0.233 0.0177 0.3 0.2965 0.9233 3063153 Maybridge4_000696 Nn1c(nc2ccccc2c1=O)C(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P15 compound treatment 0.221 0.00656 0.09 0.226 0.0107 0.18 0.1932 0.9544 1322891 Maybridge4_000697 CCOC(=O)CCc1ccc(OCc2c(C)c(C)c(C)c(C)c2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P16 compound treatment 0.196 -0.0184 -0.26 0.212 -0.00331 -0.06 -0.2258 -0.8378 3063154 Maybridge4_000698 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NCCCN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P17 compound treatment 0.211 -0.00344 -0.05 0.218 0.00269 0.05 -0.0029 -0.043 1180785 Maybridge4_000699 Cc1c(C)c(C)c(C(=O)CCc2cccc(NC(=O)C3CCC3)c2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P18 compound treatment 0.231 0.0166 0.24 0.241 0.0257 0.43 0.4724 0.9602 3063155 Maybridge4_000700 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NC(=N)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P19 compound treatment 0.224 0.00956 0.14 0.255 0.0397 0.67 0.5677 0.8349 3178924 Maybridge4_000701 N/C(=N\O)/Cc1nc(cs1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P20 compound treatment 0.247 0.0326 0.47 0.248 0.0327 0.55 0.7173 0.9967 3063157 Maybridge4_000702 Cc1nnsc1C(=O)NC(=O)Nc2cc(Cl)cc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P21 compound treatment 0.23 0.0156 0.22 0.245 0.0297 0.5 0.5097 0.934 3178925 Maybridge4_000703 CC1(C)NN(C(=N1)S)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P22 compound treatment 0.242 0.0276 0.39 0.224 0.00869 0.15 0.3819 0.9085 3063158 Maybridge4_000704 CSc1nc(nc(SC)c1Cl)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P23 mock treatment 0.215 5.62E-4 0.01 0.218 0.00269 0.05 0.0376 0.8203 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2050 P24 mock treatment 0.239 0.0246 0.35 0.198 -0.0173 -0.29 0.043 0.0942 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A01 compound treatment 0.213 -0.00347 -0.05 0.23 0.0116 0.19 0.1025 0.5105 1580862 Maybridge4_000705 CC1CC(C)CN(C1)c2ccc(NC(=O)c3ccc(Cl)cc3)cc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A02 compound treatment 0.256 0.0395 0.57 0.236 0.0176 0.3 0.6086 0.9541 3063159 Maybridge4_000706 Cc1nn(C)c(Cl)c1S(=O)(=O)Nc2ccc(C)cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A03 compound treatment 0.255 0.0385 0.55 0.243 0.0246 0.41 0.6816 0.9899 3178926 Maybridge4_000707 CN(C)/C=N/S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A04 compound treatment 0.223 0.00653 0.09 0.233 0.0146 0.24 0.2393 0.9127 3178927 Maybridge4_000708 Clc1ccc(NC(=S)N2CCCC2c3cccs3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A05 compound treatment 0.236 0.0195 0.28 0.204 -0.0144 -0.24 0.0266 0.0719 3063160 Maybridge4_000709 Cn1nccc1c2cc(F)cc(F)c2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A06 compound treatment 0.225 0.00853 0.12 0.209 -0.00941 -0.16 -0.0253 -0.127 3178928 Maybridge4_000710 O=C(NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A07 compound treatment 0.207 -0.00947 -0.14 0.226 0.00759 0.13 -0.0056 -0.0304 3063161 Maybridge4_000711 Fc1cccc(Cl)c1COC(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A08 compound treatment 0.234 0.0175 0.25 0.212 -0.00641 -0.11 0.1013 0.3712 3063162 Maybridge4_000712 CN(C)/C=C/C(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A09 compound treatment 0.222 0.00553 0.08 0.24 0.0216 0.36 0.3122 0.8416 1674451 Maybridge4_000713 CN(NS(=O)(=O)c1cc(C)c(F)c(C)c1)c2cccc(Cl)c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A10 compound treatment 0.248 0.0315 0.45 0.219 5.94E-4 0.01 0.326 0.7226 3063163 Maybridge4_000714 CN(C)/C=C/1\SCc2ccccc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A11 compound treatment 0.115 -0.101 -1.45 0.114 -0.104 -1.75 -2.2654 -0.9956 3178929 Maybridge4_000715 Cc1onc(c1C(=O)c2ccc(F)cc2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A12 compound treatment 0.227 0.0105 0.15 0.205 -0.0134 -0.23 -0.0526 -0.1942 1518860 Maybridge4_000716 COc1cccc(OC)c1C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A13 compound treatment 0.204 -0.0125 -0.18 0.229 0.0106 0.18 -4.0E-4 -0.0015 1454624 Maybridge4_000717 CC1=C(O)C(=O)OC1c2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A14 compound treatment 0.245 0.0285 0.41 0.265 0.0466 0.78 0.8416 0.954 3178930 Maybridge4_000718 Cc1nc(COc2cc(C)c(Cl)c(C)c2Cl)cs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A15 compound treatment 0.182 -0.0345 -0.49 0.195 -0.0234 -0.39 -0.6264 -0.9937 3178931 Maybridge4_000719 Clc1ccc(NC(=O)C(C#N)C(=O)c2cccs2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A16 compound treatment 0.198 -0.0185 -0.26 0.229 0.0106 0.18 -0.0611 -0.1918 1203853 Maybridge4_000720 CC1N(CCc2sccc12)C(=S)NC(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A17 compound treatment 0.216 -4.69E-4 -0.01 0.197 -0.0214 -0.36 -0.2588 -0.7202 3178932 Maybridge4_000721 CSc1nc(NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)nn1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A18 compound treatment 0.238 0.0215 0.31 0.224 0.00559 0.09 0.2842 0.8826 3063213 Maybridge4_000722 FC(F)(F)c1cccc(NC(=S)C(C#N)C(=O)N2CCCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A19 compound treatment 0.21 -0.00647 -0.09 0.212 -0.00641 -0.11 -0.1415 -0.9972 3178933 Maybridge4_000723 Cc1nn(C)c(C)c1NC(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A20 compound treatment 0.211 -0.00547 -0.08 0.187 -0.0314 -0.53 -0.428 -0.8032 1654657 Maybridge4_000724 Brc1ccc(Nc2ncnc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A21 compound treatment 0.225 0.00853 0.12 0.202 -0.0164 -0.28 -0.1084 -0.36 1162031 Maybridge4_000725 Nc1n[nH]c(NC2CCCCNC2=O)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A22 compound treatment 0.221 0.00453 0.06 0.206 -0.0124 -0.21 -0.1014 -0.465 3179020 Maybridge4_000726 C1CCN2C(=CSC2=NC1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A23 mock treatment 0.208 -0.00847 -0.12 0.211 -0.00741 -0.12 -0.1736 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 A24 mock treatment 0.227 0.0105 0.15 0.199 -0.0194 -0.33 -0.1238 -0.345 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B01 compound treatment 0.254 0.0375 0.54 0.246 0.0276 0.46 0.7071 0.9973 1499601 Maybridge4_000727 S=C(Nc1ccccc1)Nc2ccccc2c3nc4ccccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B02 compound treatment 0.253 0.0365 0.52 0.224 0.00559 0.09 0.4359 0.821 1693956 Maybridge4_000728 CSc1cc(nc(c1)c2ccc(Cl)cc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B03 compound treatment 0.222 0.00553 0.08 0.213 -0.00541 -0.09 -0.0082 -0.0683 3063216 Maybridge4_000729 CN1CNC(=NC1)SCc2ccc(C#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B04 compound treatment 0.258 0.0415 0.59 0.237 0.0186 0.31 0.6407 0.9548 3179021 Maybridge4_000730 FC(F)(F)c1ccccc1NC(=O)N/C=C/c2ccsc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B05 compound treatment 0.189 -0.0275 -0.39 0.159 -0.0594 -1.0 -0.9829 -0.9171 1138498 Maybridge4_000731 CN(C)c1ccc(cc1)C2Nc3cc(C)ccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B06 compound treatment 0.248 0.0315 0.45 0.242 0.0236 0.4 0.5989 0.9979 3179022 Maybridge4_000732 CC1=CC(=O)N(C1=O)c2ccn(C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B07 compound treatment 0.239 0.0225 0.32 0.251 0.0326 0.55 0.6147 0.9682 3179023 Maybridge4_000733 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B08 compound treatment 0.254 0.0375 0.54 0.191 -0.0274 -0.46 0.0543 0.0769 3063218 Maybridge4_000734 CCCc1c(cnn1c2ccccc2)c3nc(no3)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B09 compound treatment 0.245 0.0285 0.41 0.231 0.0126 0.21 0.438 0.9531 3179024 Maybridge4_000735 FC(F)(F)c1cccc(NC2(CCCCCC2)C#N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B10 compound treatment 0.243 0.0265 0.38 0.256 0.0376 0.63 0.7145 0.9704 1512806 Maybridge4_000736 Cc1csc2c(ncnc12)N3CCSCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B11 compound treatment 0.253 0.0365 0.52 0.233 0.0146 0.24 0.5427 0.9404 1281080 Maybridge4_000737 CS(=O)(=O)N1CCCN2C1c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B12 compound treatment 0.25 0.0335 0.48 0.226 0.00759 0.13 0.4293 0.865 3179025 Maybridge4_000738 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2noc(n2)C3CCc4ccccc4O3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B13 compound treatment 0.247 0.0305 0.44 0.225 0.00659 0.11 0.3871 0.8591 3063220 Maybridge4_000739 Cc1c(C)c(C)c(CSCc2n[nH]c(=S)n2c3ccc(F)cc3)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B14 compound treatment 0.21 -0.00647 -0.09 0.219 5.94E-4 0.01 -0.0584 -0.6273 3179026 Maybridge4_000740 Cc1csc2ncnc(Sc3ccccc3NS(=O)(=O)c4ccc(F)cc4)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B15 compound treatment 0.212 -0.00447 -0.06 0.218 -4.06E-4 -0.01 -0.05 -0.7781 3063222 Maybridge4_000741 CS/C(=N\C(=O)c1c(Cl)cccc1Cl)/N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B16 compound treatment 0.214 -0.00247 -0.04 0.204 -0.0144 -0.24 -0.1959 -0.8019 1691561 Maybridge4_000742 Cc1csc2ncnc(N3CCN(CC3)C(=S)NCC4CC4)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B17 compound treatment 0.244 0.0275 0.39 0.244 0.0256 0.43 0.5822 0.9991 1442583 Maybridge4_000743 Cc1ccc(C(=S)N)c(O)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B18 compound treatment 0.235 0.0185 0.27 0.235 0.0166 0.28 0.3844 0.9997 1597708 Maybridge4_000744 COc1cc2CCNC(=O)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B19 compound treatment 0.046 -0.17 -2.44 0.048 -0.17 -2.86 -3.7466 -0.9968 3179027 Maybridge4_000745 FC(F)(F)Oc1ccc(cc1)n2c(=N)c(/N=C/c3ccc(cc3)C(F)(F)F)c(C#N)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B20 compound treatment 0.198 -0.0185 -0.26 0.192 -0.0264 -0.44 -0.5002 -0.9694 1614161 Maybridge4_000746 Cc1csc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)c1C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B21 compound treatment 0.25 0.0335 0.48 0.27 0.0516 0.87 0.9515 0.9612 3179028 Maybridge4_000747 Cc1csc(NC(=O)CSc2ccc(Cl)cc2)c1C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B22 compound treatment 0.25 0.0335 0.48 0.248 0.0296 0.5 0.6904 0.9998 3063278 Maybridge4_000748 NNC(=S)Nc1ccccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B23 mock treatment 0.217 5.31E-4 0.01 0.231 0.0126 0.21 0.1548 0.7321 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 B24 mock treatment 0.215 -0.00147 -0.02 0.235 0.0166 0.28 0.1821 0.6519 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C01 compound treatment 0.196 -0.0205 -0.29 0.214 -0.00441 -0.07 -0.2593 -0.8587 3179029 Maybridge4_000749 Cc1cc(C)n(Cc2c(Cl)cccc2Cl)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C02 compound treatment 0.254 0.0375 0.54 0.204 -0.0144 -0.24 0.2086 0.3543 3063279 Maybridge4_000750 CC1SCC(CS1)NC(=O)c2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C03 compound treatment 0.248 0.0315 0.45 0.185 -0.0334 -0.56 -0.0776 -0.1078 3179030 Maybridge4_000751 CC(C)(C)n1cnnc1S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C04 compound treatment 0.239 0.0225 0.32 0.226 0.00759 0.13 0.318 0.9176 3179031 Maybridge4_000752 Cc1c(cnn1c2ccc(Cl)cc2)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C05 compound treatment 0.234 0.0175 0.25 0.226 0.00759 0.13 0.2674 0.9507 3063283 Maybridge4_000753 CN(C)/C=c/1\s\c(=C\C(=O)c2cccs2)\[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C06 compound treatment 0.267 0.0505 0.72 0.211 -0.00741 -0.12 0.4232 0.577 3179032 Maybridge4_000754 Fc1ccc(c2ccc(o2)c3ccnn3S(=O)(=O)c4ccc(F)cc4F)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C07 compound treatment 0.259 0.0425 0.61 0.239 0.0206 0.35 0.6746 0.9641 3063284 Maybridge4_000755 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)N2CCSCC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C08 compound treatment 0.267 0.0505 0.72 0.217 -0.00141 -0.02 0.4944 0.6837 3179033 Maybridge4_000756 NC(=O)N/C(=N/O)/CSCc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C09 compound treatment 0.27 0.0535 0.77 0.235 0.0166 0.28 0.7384 0.9062 3063285 Maybridge4_000757 Fc1cc(CSc2ccc(Cl)cc2)c3OCOCc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C10 compound treatment 0.24 0.0235 0.34 0.233 0.0146 0.24 0.4112 0.9878 1433051 Maybridge4_000758 CCOC(=O)Cc1nc(N)ncc1C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C11 compound treatment 0.1 -0.116 -1.67 0.101 -0.117 -1.97 -2.5714 -0.9965 1461982 Maybridge4_000759 Cc1onc(c1C(O)c2ccc(F)cc2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C12 compound treatment 0.238 0.0215 0.31 0.19 -0.0284 -0.48 -0.1194 -0.2103 1346508 Maybridge4_000760 COc1ccc2C(NN(C)c3cccc(F)c3C#N)OC(=O)c2c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C13 compound treatment 0.217 5.31E-4 0.01 0.217 -0.00141 -0.02 -0.0113 -0.4564 3179034 Maybridge4_000761 CN(C)/C=N/C(=S)NC1CC2CC1C=C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C14 compound treatment 0.195 -0.0215 -0.31 0.241 0.0226 0.38 0.051 0.1045 1675569 Maybridge4_000762 C(N1CC(CN(Cc2ccccc2)C1)c3nn[nH]n3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C15 compound treatment 0.215 -0.00147 -0.02 0.249 0.0306 0.51 0.3482 0.6776 3063288 Maybridge4_000763 CNC(=O)n1cc(c(C)n1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C16 compound treatment 0.206 -0.0105 -0.15 0.18 -0.0384 -0.64 -0.5617 -0.8488 1260907 Maybridge4_000764 CC1N(CCc2sccc12)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C17 compound treatment 0.213 -0.00347 -0.05 0.239 0.0206 0.35 0.2093 0.5995 1246781 Maybridge4_000765 CN(C)c1cccc(N(C)C)c1CNC(=O)c2ccccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C18 compound treatment 0.04 -0.176 -2.52 0.041 -0.177 -2.98 -3.8903 -0.9966 3179035 Maybridge4_000766 FC(F)(F)c1cccc(NC(=O)C(C#N)C(=S)Nc2ccccc2Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C19 compound treatment 0.214 -0.00247 -0.04 0.192 -0.0264 -0.44 -0.3384 -0.761 3063289 Maybridge4_000767 CNC(=O)N1CCCC(Cn2cccc2)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C20 compound treatment 0.213 -0.00347 -0.05 0.225 0.00659 0.11 0.0432 0.356 1385501 Maybridge4_000768 Cc1ccc(cc1)c2csc(=N)n2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C21 compound treatment 0.211 -0.00547 -0.08 0.22 0.00159 0.03 -0.0364 -0.4403 1144063 Maybridge4_000769 Clc1ccc(NC(=O)NC2CCCCNC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C22 compound treatment 0.205 -0.0115 -0.16 0.201 -0.0174 -0.29 -0.3226 -0.9628 3179036 Maybridge4_000770 CC1CN=C(N1)SCc2c(C)c(C)c(C)c(C)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C23 mock treatment 0.178 -0.0385 -0.55 0.211 -0.00741 -0.12 -0.477 -0.8455 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 C24 mock treatment 0.232 0.0155 0.22 0.211 -0.00741 -0.12 0.0692 0.2718 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D01 compound treatment 0.226 0.00953 0.14 0.208 -0.0104 -0.17 -0.0271 -0.1223 3063290 Maybridge4_000771 CSC1=NCCN1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D02 compound treatment 0.212 -0.00447 -0.06 0.181 -0.0374 -0.63 -0.4891 -0.7751 3179037 Maybridge4_000772 COC(=O)c1sc(cc1NC(=O)Nc2ccc(Cl)cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D03 compound treatment 0.24 0.0235 0.34 0.219 5.94E-4 0.01 0.245 0.7277 3063291 Maybridge4_000773 Cc1ccc(Cc2nc(cs2)c3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D04 compound treatment 0.219 0.00253 0.04 0.14 -0.0784 -1.32 -0.9049 -0.6874 3179038 Maybridge4_000774 FC(F)(F)c1cc(SC(=O)N/C=C/c2ccsc2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D05 compound treatment 0.19 -0.0265 -0.38 0.195 -0.0234 -0.39 -0.5455 -0.9998 1247834 Maybridge4_000775 CC(C)(C)CC(C)(C)N1CNC(=S)NC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D06 compound treatment 0.099 -0.117 -1.68 0.098 -0.12 -2.02 -2.6171 -0.9958 3179039 Maybridge4_000776 Cn1cc(Br)c(n1)N2C(=O)C=CC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D07 compound treatment 0.204 -0.0125 -0.18 0.247 0.0286 0.48 0.2132 0.4165 3179040 Maybridge4_000777 COc1cc(cc(OC)c1OC)C(O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D08 compound treatment 0.28 0.0635 0.91 0.184 -0.0344 -0.58 0.2342 0.2175 3063293 Maybridge4_000778 CCCc1nn(cc1C(=O)Nc2ccc(Cl)cc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D09 compound treatment 0.301 0.0845 1.21 0.183 -0.0354 -0.59 0.4348 0.3227 1432923 Maybridge4_000779 CC(NC(=O)c1c(C)onc1c2ccccc2Cl)c3ccc(C)cc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D10 compound treatment 0.28 0.0635 0.91 0.256 0.0376 0.63 1.0887 0.9841 3179041 Maybridge4_000780 FC(F)(F)c1c(cnn1c2ccc(Cl)cc2)C(=O)NCCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D11 compound treatment 0.25 0.0335 0.48 0.252 0.0336 0.56 0.7378 0.9968 3179119 Maybridge4_000781 COc1cc(cc(OC)c1OC)C(=O)N2/C(=N/c3ccccc3Cl)/SC(=C)C2(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D12 compound treatment 0.293 0.0765 1.09 0.229 0.0106 0.18 0.8998 0.8113 3062512 Maybridge4_000782 COC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D13 compound treatment 0.285 0.0685 0.98 0.236 0.0176 0.3 0.9019 0.881 1164825 Maybridge4_000783 NNC(=O)Oc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D14 compound treatment 0.229 0.0125 0.18 0.279 0.0606 1.02 0.8459 0.8191 3179120 Maybridge4_000784 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)/C=C/C(=O)O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D15 compound treatment 0.246 0.0295 0.42 0.274 0.0556 0.93 0.9585 0.9358 3062514 Maybridge4_000785 Clc1cccc(Cl)c1C(=O)N=C2NCCCN2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D16 compound treatment 0.295 0.0785 1.12 0.298 0.0796 1.34 1.7389 0.9963 3179121 Maybridge4_000786 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D17 compound treatment 0.272 0.0555 0.79 0.264 0.0456 0.77 1.1028 0.9998 3062515 Maybridge4_000787 CCOC(=O)C1=C(C)NC(=NC1c2cccs2)SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D18 compound treatment 0.228 0.0115 0.16 0.217 -0.00141 -0.02 0.0999 0.5998 3179122 Maybridge4_000788 CCOC(=O)c1cnc(SCc2c(C)cc(C)cc2C)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D19 compound treatment 0.28 0.0635 0.91 0.243 0.0246 0.41 0.9345 0.9362 1515946 Maybridge4_000789 Fc1ccc(cc1)C(=O)ON(C2C3CC4CC(C3)CC2C4)C(=O)c5ccc(F)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D20 compound treatment 0.287 0.0705 1.01 0.225 0.00659 0.11 0.7916 0.78 1700551 Maybridge4_000790 COC(=O)CNS(=O)(=O)c1ccsc1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D21 compound treatment 0.234 0.0175 0.25 0.229 0.0106 0.18 0.303 0.9858 1564868 Maybridge4_000791 Clc1cc(Cl)cc(c1)c2nnc(o2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D22 compound treatment 0.26 0.0435 0.62 0.236 0.0176 0.3 0.6491 0.9419 3179123 Maybridge4_000792 COc1cc2ncnc(NCCCn3ccnc3)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D23 mock treatment 0.215 -0.00147 -0.02 0.235 0.0166 0.28 0.1821 0.6519 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 D24 mock treatment 0.213 -0.00347 -0.05 0.229 0.0106 0.18 0.0906 0.491 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E01 compound treatment 0.225 0.00853 0.12 0.211 -0.00741 -0.12 -0.0016 -0.0092 3062517 Maybridge4_000793 CCc1nc2ccccc2nc1CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E02 compound treatment 0.205 -0.0115 -0.16 0.18 -0.0384 -0.64 -0.5718 -0.8597 3179124 Maybridge4_000794 Cc1nc(S)c(C#N)c(C)c1Cc2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E03 compound treatment 0.237 0.0205 0.29 0.213 -0.00541 -0.09 0.1435 0.4668 3062519 Maybridge4_000795 Fc1cccc(CSCc2c(F)cccc2Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E04 compound treatment 0.224 0.00753 0.11 0.211 -0.00741 -0.12 -0.0117 -0.0713 3179125 Maybridge4_000796 CN(C)/C=N/S(=O)(=O)c1c(C)noc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E05 compound treatment 0.246 0.0295 0.42 0.219 5.94E-4 0.01 0.3057 0.7236 3062520 Maybridge4_000797 CCOc1ccccc1CCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E06 compound treatment 0.261 0.0445 0.64 0.231 0.0126 0.21 0.5999 0.8938 3179126 Maybridge4_000798 COc1ccc(NS(=O)(=O)c2ccc(Oc3c(C#N)cccc3C#N)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E07 compound treatment 0.246 0.0295 0.42 0.245 0.0266 0.45 0.6143 0.9996 3062522 Maybridge4_000799 Clc1ccc(cc1)S(=O)(=O)NC(=N)N2CCSCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E08 compound treatment 0.287 0.0705 1.01 0.255 0.0366 0.61 1.1477 0.9717 3179127 Maybridge4_000800 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2ccnc(NC(=O)Nc3ccccc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E09 compound treatment 0.262 0.0455 0.65 0.227 0.00859 0.14 0.5625 0.8433 1521882 Maybridge4_000801 Clc1ccccc1C(=O)NC(=O)OCc2cccc(Oc3ccccc3)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E10 compound treatment 0.259 0.0425 0.61 0.267 0.0486 0.82 1.0069 0.9896 3179128 Maybridge4_000802 O=C(c1ccccc1)n2cc3SCc4ccccc4-c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E11 compound treatment 0.253 0.0365 0.52 0.226 0.00759 0.13 0.4596 0.8545 1615025 Maybridge4_000803 Fc1ccc(cc1)C(=O)CCC(=O)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E12 compound treatment 0.312 0.0955 1.37 0.257 0.0386 0.65 1.4243 0.9418 1276755 Maybridge4_000804 CN(n1cnc2ccsc2c1=O)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E13 compound treatment 0.288 0.0715 1.02 0.233 0.0146 0.24 0.8967 0.8523 1254744 Maybridge4_000805 Clc1ccc(NC(=O)NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E14 compound treatment 0.249 0.0325 0.47 0.273 0.0546 0.92 0.977 0.9506 1341148 Maybridge4_000806 O=C(Nc1ccccc1)n2nnc(n2)C3CN(Cc4ccccc4)CN(Cc5ccccc5)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E15 compound treatment 0.253 0.0365 0.52 0.215 -0.00341 -0.06 0.3291 0.626 1687071 Maybridge4_000807 CNC(=O)NCc1c(cccc1N(C)C)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E16 compound treatment 0.246 0.0295 0.42 0.239 0.0206 0.35 0.5431 0.995 3179129 Maybridge4_000808 NC(=O)/C(=C/1\SC=C(N1Cc2ccccc2)c3ccccc3)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E17 compound treatment 0.217 5.31E-4 0.01 0.244 0.0256 0.43 0.3091 0.7195 3062558 Maybridge4_000809 CCc1cnc(/N=C/N(C)C)nc1c2c(F)cccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E18 compound treatment 0.206 -0.0105 -0.15 0.199 -0.0194 -0.33 -0.3362 -0.9378 3179130 Maybridge4_000810 Cc1nc(c(s1)c2ccccc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E19 compound treatment 0.27 0.0535 0.77 0.225 0.00659 0.11 0.6197 0.801 3062560 Maybridge4_000811 COC(CNC(=S)Nc1ccccc1Cl)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E20 compound treatment 0.248 0.0315 0.45 0.211 -0.00741 -0.12 0.231 0.4938 1542710 Maybridge4_000812 COc1ccc(CCn2nnc3ccccc3c2=O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E21 compound treatment 0.217 5.31E-4 0.01 0.247 0.0286 0.48 0.3447 0.7182 1303354 Maybridge4_000813 CC(C)NC(=O)NC1CCCCNC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E22 compound treatment 0.235 0.0185 0.27 0.231 0.0126 0.21 0.3369 0.9937 3062562 Maybridge4_000814 O=C(N1C(Oc2ccccc12)c3ccc4OCOc4c3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E23 mock treatment 0.237 0.0205 0.29 0.219 5.94E-4 0.01 0.2147 0.7307 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 E24 mock treatment 0.202 -0.0145 -0.21 0.217 -0.00141 -0.02 -0.163 -0.7827 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F01 compound treatment 0.239 0.0225 0.32 0.229 0.0106 0.18 0.3536 0.9607 3179131 Maybridge4_000815 CN1CNC(=NC1)SCc2c(C)c(C)c(C)c(C)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F02 compound treatment 0.209 -0.00747 -0.11 0.214 -0.00441 -0.07 -0.1278 -0.9839 3062563 Maybridge4_000816 Cn1ncc(C(=O)O)c1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F03 compound treatment 0.238 0.0215 0.31 0.206 -0.0124 -0.21 0.0705 0.1897 3179132 Maybridge4_000817 C(SC1=NCCCN1C2CCCCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F04 compound treatment 0.263 0.0465 0.67 0.256 0.0376 0.63 0.9168 0.9996 3062565 Maybridge4_000818 Cc1cc(SC(=O)N/C=C/c2ccco2)c(C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F05 compound treatment 0.145 -0.0715 -1.02 0.108 -0.11 -1.85 -2.0332 -0.9607 1151481 Maybridge4_000819 CC(=O)Nc1ccc(cc1)C2Nc3cc(C)ccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F06 compound treatment 0.239 0.0225 0.32 0.249 0.0306 0.51 0.591 0.9748 1566379 Maybridge4_000820 O=C1CCC(=O)N1c2sc3CCCCc3c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F07 compound treatment 0.283 0.0665 0.95 0.293 0.0746 1.25 1.5582 0.9908 1625831 Maybridge4_000821 CC(C)(C)n1c(n[nH]c1=S)c2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F08 compound treatment 0.28 0.0635 0.91 0.259 0.0406 0.68 1.1243 0.9899 3179133 Maybridge4_000822 CCCc1c(cnn1c2ccccc2)C(=O)Sc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F09 compound treatment 0.258 0.0415 0.59 0.278 0.0596 1.0 1.1273 0.969 1730421 Maybridge4_000823 CC(NC(=O)c1ccccc1C(=O)NC(C)c2ccc3OCCOc3c2)c4ccc5OCCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F10 compound treatment 0.247 0.0305 0.44 0.245 0.0266 0.45 0.6244 0.9999 3062566 Maybridge4_000824 COC(=O)c1sccc1NN2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F11 compound treatment 0.223 0.00653 0.09 0.225 0.00659 0.11 0.1443 0.9964 1672433 Maybridge4_000825 Cc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)C(C#N)c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F12 compound treatment 0.287 0.0705 1.01 0.276 0.0576 0.97 1.3969 0.9998 3179134 Maybridge4_000826 COC(=O)c1cnc(NN2C(=O)CCC2=O)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F13 compound treatment 0.33 0.114 1.62 0.279 0.0606 1.02 1.8674 0.9746 3179135 Maybridge4_000827 FC(F)(F)c1cccc(NC(=S)N(CCC#N)C2CCCCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F14 compound treatment 0.271 0.0545 0.78 0.212 -0.00641 -0.11 0.4755 0.6039 3062567 Maybridge4_000828 COC(=O)c1c(C)sc2c(cc(=O)[nH]c12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F15 compound treatment 0.264 0.0475 0.68 0.273 0.0546 0.92 1.1287 0.9892 3062568 Maybridge4_000829 Clc1cccc(Cl)c1C(=O)N=C2NCCN2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F16 compound treatment 0.319 0.103 1.47 0.27 0.0516 0.87 1.6493 0.9684 1243939 Maybridge4_000830 COC(=O)c1ccsc1NC(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F17 compound treatment 0.267 0.0505 0.72 0.261 0.0426 0.71 1.0166 1.0 3062570 Maybridge4_000831 S=C1CCc2ccccc2N1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F18 compound treatment 0.333 0.117 1.67 0.313 0.0946 1.59 2.3013 0.9997 3179136 Maybridge4_000832 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)c3ccc(Cl)cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F19 compound treatment 0.224 0.00753 0.11 0.22 0.00159 0.03 0.0951 0.8567 3179137 Maybridge4_000833 FC(F)(F)Oc1ccc(NC(=O)N/C(=C(\N=C/c2ccc(Cl)cc2)/C#N)/C#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F20 compound treatment 0.24 0.0235 0.34 0.251 0.0326 0.55 0.6248 0.9728 1627087 Maybridge4_000834 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F21 compound treatment 0.269 0.0525 0.75 0.257 0.0386 0.65 0.9893 0.9973 3062571 Maybridge4_000835 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nnc(o2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F22 compound treatment 0.249 0.0325 0.47 0.22 0.00159 0.03 0.3479 0.7465 3179138 Maybridge4_000836 COc1cc2ncnc(NCCCN3CCOCC3)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F23 mock treatment 0.223 0.00653 0.09 0.239 0.0206 0.35 0.3105 0.8671 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 F24 mock treatment 0.222 0.00553 0.08 0.233 0.0146 0.24 0.2291 0.8902 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G01 compound treatment 0.242 0.0255 0.37 0.236 0.0176 0.3 0.467 0.9944 3179214 Maybridge4_000837 CC(C)(C)C(=N)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G02 compound treatment 0.244 0.0275 0.39 0.193 -0.0254 -0.43 -0.0231 -0.0397 1694181 Maybridge4_000838 O=C(Nc1ccccc1)Nc2ccccc2C(=O)NC3CCSC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G03 compound treatment 0.228 0.0115 0.16 0.252 0.0336 0.56 0.5153 0.8772 3179215 Maybridge4_000839 Cc1onc(c1CSc2nncn2C(C)(C)C)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G04 compound treatment 0.236 0.0195 0.28 0.219 5.94E-4 0.01 0.2046 0.7319 3062572 Maybridge4_000840 FC(F)(F)c1cccc(c1)C(C#N)c2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G05 compound treatment 0.242 0.0255 0.37 0.253 0.0346 0.58 0.6688 0.975 3179216 Maybridge4_000841 CN(C)/C=C/1\CC(=C(O)C1=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G06 compound treatment 0.32 0.104 1.48 0.205 -0.0134 -0.23 0.888 0.5929 3062573 Maybridge4_000842 CSc1cc(nn1S(=O)(=O)c2ccc(F)cc2F)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G07 compound treatment 0.29 0.0735 1.05 0.262 0.0436 0.73 1.2611 0.9843 3179217 Maybridge4_000843 Fc1ccc(NC(=O)NC(=O)Cc2c(F)cccc2Cl)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G08 compound treatment 0.26 0.0435 0.62 0.277 0.0586 0.98 1.1357 0.9757 1112281 Maybridge4_000844 Clc1ccc(cc1)S(=O)(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G09 compound treatment 0.189 -0.0275 -0.39 0.176 -0.0424 -0.71 -0.7811 -0.9608 3179218 Maybridge4_000845 CC(C)(C)c1nc(NC(=N)N)sc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G10 compound treatment 0.295 0.0785 1.12 0.232 0.0136 0.23 0.9556 0.8337 1361037 Maybridge4_000846 N#CC1CN(Cc2cccs2)CN(Cc3cccs3)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G11 compound treatment 0.294 0.0775 1.11 0.258 0.0396 0.66 1.2541 0.97 3062574 Maybridge4_000847 CSCC(CSC)OC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G12 compound treatment 0.288 0.0715 1.02 0.305 0.0866 1.45 1.7512 0.9852 3179219 Maybridge4_000848 CN(n1cnc2ccsc2c1=O)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G13 compound treatment 0.273 0.0565 0.81 0.261 0.0426 0.71 1.0773 0.9981 3179220 Maybridge4_000849 CN(C)/C=N/C1=C(C(=O)c2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G14 compound treatment 0.269 0.0525 0.75 0.237 0.0186 0.31 0.752 0.9242 3062606 Maybridge4_000850 CC1N(CCc2sccc12)C(=O)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G15 compound treatment 0.266 0.0495 0.71 0.293 0.0746 1.25 1.3863 0.9637 1282646 Maybridge4_000851 CN(C(=O)Nc1ccc(Cl)cc1)n2cnc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G16 compound treatment 0.275 0.0585 0.84 0.215 -0.00341 -0.06 0.5516 0.6573 3179221 Maybridge4_000852 CCOC(=O)/C(=C/1\SC=C(N1c2c(C)cccc2C)c3ccccc3)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G17 compound treatment 0.253 0.0365 0.52 0.229 0.0106 0.18 0.4952 0.8972 3062608 Maybridge4_000853 CNC(=O)n1cc(C)c(n1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G18 compound treatment 0.242 0.0255 0.37 0.225 0.00659 0.11 0.3365 0.8818 1645665 Maybridge4_000854 Cc1ccc(cc1C)c2nn(CCO)c(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G19 compound treatment 0.241 0.0245 0.35 0.229 0.0106 0.18 0.3738 0.9504 1361478 Maybridge4_000855 Cc1nn(C)c(C)c1Nc2nc(N)n[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G20 compound treatment 0.212 -0.00447 -0.06 0.214 -0.00441 -0.07 -0.0975 -0.9974 3179222 Maybridge4_000856 CC1CN(CC(C)O1)C(=N)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G21 compound treatment 0.185 -0.0315 -0.45 0.22 0.00159 0.03 -0.2994 -0.6639 3062610 Maybridge4_000857 Clc1ccc(SS(=O)(=O)CS(=O)(=O)Sc2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G22 compound treatment 0.146 -0.0705 -1.01 0.163 -0.0554 -0.93 -1.3703 -0.9992 3179223 Maybridge4_000858 Clc1ccc(cc1Cl)C2Nc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G23 mock treatment 0.201 -0.0155 -0.22 0.211 -0.00741 -0.12 -0.2444 -0.9628 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 G24 mock treatment 0.21 -0.00647 -0.09 0.184 -0.0344 -0.58 -0.4738 -0.8101 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H01 compound treatment 0.222 0.00553 0.08 0.218 -4.06E-4 -0.01 0.0511 0.6438 3062611 Maybridge4_000859 CCN1CNC(=NC1)SCc2c(C)c(C)c(C)c(C)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H02 compound treatment 0.191 -0.0255 -0.36 0.167 -0.0514 -0.86 -0.8677 -0.9265 3179224 Maybridge4_000860 CCOC(=O)c1sc(SC)nc1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H03 compound treatment 0.22 0.00353 0.05 0.225 0.00659 0.11 0.114 0.9369 1702677 Maybridge4_000861 COc1ccc(CCNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H04 compound treatment 0.271 0.0545 0.78 0.255 0.0366 0.61 0.9858 0.993 1349117 Maybridge4_000862 CCOC(=O)c1cnn(C)c1NS(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H05 compound treatment 0.249 0.0325 0.47 0.262 0.0436 0.73 0.8464 0.9761 3179225 Maybridge4_000863 COc1ccc(C/N=C/c2ccc(NC(=O)C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H06 compound treatment 0.095 -0.121 -1.74 0.077 -0.141 -2.37 -2.9068 -0.9882 3062612 Maybridge4_000864 FC(F)(F)c1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C=CC3=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H07 compound treatment 0.283 0.0665 0.95 0.266 0.0476 0.8 1.2378 0.9962 1216743 Maybridge4_000865 Clc1ccc(cc1)C(=C)NCc2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H08 compound treatment 0.323 0.107 1.52 0.272 0.0536 0.9 1.7135 0.9684 3062613 Maybridge4_000866 CSc1cc(nn1S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H09 compound treatment 0.267 0.0505 0.72 0.243 0.0246 0.41 0.803 0.9647 1649762 Maybridge4_000867 CC1C(OCCN1C(=O)CCN2C(=O)c3ccccc3C2=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H10 compound treatment 0.263 0.0465 0.67 0.186 -0.0324 -0.54 0.086 0.1001 3062614 Maybridge4_000868 COC(=O)c1scc(C)c1NN2C(=O)C=C(C)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H11 compound treatment 0.293 0.0765 1.09 0.305 0.0866 1.45 1.8018 0.9902 1683075 Maybridge4_000869 CC1CC(CC(C)(C)C1)N(CCC#N)S(=O)(=O)c2ccc(Br)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H12 compound treatment 0.28 0.0635 0.91 0.256 0.0376 0.63 1.0887 0.9841 3062615 Maybridge4_000870 COC(=O)c1sc2cc(sc2c1C)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H13 compound treatment 0.304 0.0875 1.25 0.294 0.0756 1.27 1.7825 1.0 3179226 Maybridge4_000871 Cc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H14 compound treatment 0.303 0.0865 1.24 0.296 0.0776 1.3 1.7961 0.9997 3062616 Maybridge4_000872 COC(=O)c1cc2c(nn(C)c2s1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H15 compound treatment 0.302 0.0855 1.22 0.308 0.0896 1.5 1.9284 0.9948 3179227 Maybridge4_000873 COc1ccc(cc1)c2c(N)nc(nc2SC)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H16 compound treatment 0.286 0.0695 0.99 0.285 0.0666 1.12 1.4936 0.9983 3179228 Maybridge4_000874 CC(=O)N(c1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc(cc2)N3C(=O)CCC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H17 compound treatment 0.254 0.0375 0.54 0.203 -0.0154 -0.26 0.1968 0.3302 1612694 Maybridge4_000875 Nc1nc2Oc3ccc(Br)cc3C4C(C#N)C(O)(Nc(c1C#N)c42)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H18 compound treatment 0.281 0.0645 0.92 0.269 0.0506 0.85 1.2531 0.9991 1678485 Maybridge4_000876 Cn1nccc1NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H19 compound treatment 0.286 0.0695 0.99 0.25 0.0316 0.53 1.0782 0.9566 3062617 Maybridge4_000877 CC(C)/N=C/c1ccc(cc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H20 compound treatment 0.226 0.00953 0.14 0.259 0.0406 0.68 0.5782 0.8321 3179229 Maybridge4_000878 Cn1nccc1NC(=O)/C=C/C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H21 compound treatment 0.289 0.0725 1.04 0.261 0.0426 0.71 1.2391 0.9835 3062618 Maybridge4_000879 Cn1ccc(NC(=O)NC(=O)c2c(F)cccc2F)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H22 compound treatment 0.211 -0.00547 -0.08 0.203 -0.0154 -0.26 -0.2382 -0.8816 1656689 Maybridge4_000880 OCCNc1ncnc2sc3CCCCc3c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H23 mock treatment 0.216 -4.69E-4 -0.01 0.247 0.0286 0.48 0.3346 0.6972 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 H24 mock treatment 0.209 -0.00747 -0.11 0.219 5.94E-4 0.01 -0.0685 -0.6384 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I01 compound treatment 0.229 0.0125 0.18 0.191 -0.0274 -0.46 -0.1985 -0.4021 3062619 Maybridge4_000881 Cc1n[nH]c(C)c1Cc2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I02 compound treatment 0.197 -0.0195 -0.28 0.22 0.00159 0.03 -0.178 -0.6363 1705532 Maybridge4_000882 O=C(Nc1ccccc1)N2CCCC2c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I03 compound treatment 0.175 -0.0415 -0.59 0.151 -0.0674 -1.13 -1.2194 -0.9546 3062620 Maybridge4_000883 Nc1ccccc1C2C=NNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I04 compound treatment 0.249 0.0325 0.47 0.247 0.0286 0.48 0.6684 0.9999 3179230 Maybridge4_000884 Fc1c(COC(=O)c2ccccc2)cccc1COC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I05 compound treatment 0.269 0.0525 0.75 0.261 0.0426 0.71 1.0368 0.9997 3062621 Maybridge4_000885 CSC(=S)N(C)/N=C/c1cc(Cl)cc(Cl)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I06 compound treatment 0.26 0.0435 0.62 0.241 0.0226 0.38 0.7084 0.9717 3179231 Maybridge4_000886 Cc1nc(NC(=N)NC(=O)Nc2ccc(Cl)cc2)sc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I07 compound treatment 0.284 0.0675 0.97 0.277 0.0586 0.98 1.3784 1.0 3062622 Maybridge4_000887 Fc1ccccc1C(=O)Oc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I08 compound treatment 0.263 0.0465 0.67 0.209 -0.00941 -0.16 0.359 0.5248 3179232 Maybridge4_000888 Clc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I09 compound treatment 0.269 0.0525 0.75 0.255 0.0366 0.61 0.9656 0.995 1166421 Maybridge4_000889 Fc1cc(CSc2nc3ccccc3s2)c4OCOCc4c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I10 compound treatment 0.236 0.0195 0.28 0.268 0.0496 0.83 0.7861 0.8953 1473503 Maybridge4_000890 OC(=O)C1(CN(CCc2ccc(Cl)cc2)CN(CCc3ccc(Cl)cc3)C1)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I11 compound treatment 0.238 0.0215 0.31 0.253 0.0346 0.58 0.6283 0.956 3179233 Maybridge4_000891 FC(F)(F)c1cc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I12 compound treatment 0.286 0.0695 0.99 0.296 0.0776 1.3 1.6241 0.9911 3062667 Maybridge4_000892 COc1cccc(OC)c1SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I13 compound treatment 0.275 0.0585 0.84 0.244 0.0256 0.43 0.8957 0.9519 3062668 Maybridge4_000893 C/C(=N\O)/Cc1ncn(n1)c2cc(C)on2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I14 compound treatment 0.242 0.0255 0.37 0.254 0.0356 0.6 0.6807 0.9721 3179234 Maybridge4_000894 Clc1ccc(/C=N/N2CCOCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I15 compound treatment 0.307 0.0905 1.29 0.256 0.0376 0.63 1.3618 0.9454 3062670 Maybridge4_000895 OCCCc1cc(n[nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I16 compound treatment 0.249 0.0325 0.47 0.169 -0.0494 -0.83 -0.2573 -0.2706 3179329 Maybridge4_000896 O=C(CC#N)Nc1ccncc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I17 compound treatment 0.268 0.0515 0.74 0.2 -0.0184 -0.31 0.3028 0.3788 3062671 Maybridge4_000897 CN(C)/C=C/C(=O)c1nnn(c1C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I18 compound treatment 0.259 0.0425 0.61 0.203 -0.0154 -0.26 0.2473 0.3742 1670735 Maybridge4_000898 OCCn1nc(c2ccc(F)cc2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I19 compound treatment 0.239 0.0225 0.32 0.235 0.0166 0.28 0.4248 0.9974 3179330 Maybridge4_000899 Cc1onc(c1NC(=O)NC2CCSC2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I20 compound treatment 0.207 -0.00947 -0.14 0.261 0.0426 0.71 0.4097 0.5631 3062672 Maybridge4_000900 CSC1=NNC(N1)c2ccc(cc2)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I21 compound treatment 0.239 0.0225 0.32 0.239 0.0206 0.35 0.4723 0.9994 3062673 Maybridge4_000901 CSc1nc(/N=C/N(C)C)nn1CCC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I22 compound treatment 0.198 -0.0185 -0.26 0.188 -0.0304 -0.51 -0.5477 -0.953 1639939 Maybridge4_000902 Cc1ccc(cc1)S(=O)(=O)N2C(Oc3ccccc23)c4ccc(Cl)c(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I23 mock treatment 0.206 -0.0105 -0.15 0.217 -0.00141 -0.02 -0.1226 -0.8086 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 I24 mock treatment 0.212 -0.00447 -0.06 0.226 0.00759 0.13 0.0449 0.3151 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J01 compound treatment 0.204 -0.0125 -0.18 0.24 0.0216 0.36 0.1302 0.3222 3062674 Maybridge4_000903 CCN1CNC(=NC1)SCc2cccc(C#N)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J02 compound treatment 0.226 0.00953 0.14 0.237 0.0186 0.31 0.3171 0.931 3179331 Maybridge4_000904 CCCc1c(cnn1C)C(=O)Nc2cc(F)ccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J03 compound treatment 0.23 0.0135 0.19 0.232 0.0136 0.23 0.2982 0.9966 3179332 Maybridge4_000905 CC(O)CN1CNC(=NC1)SCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J04 compound treatment 0.251 0.0345 0.49 0.219 5.94E-4 0.01 0.3563 0.7212 3062676 Maybridge4_000906 COC(=O)c1sc(cc1NC(=O)C(F)(F)F)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J05 compound treatment 0.249 0.0325 0.47 0.248 0.0296 0.5 0.6802 0.9995 3179333 Maybridge4_000907 OCCN1CNC(=NC1)SCc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J06 compound treatment 0.252 0.0355 0.51 0.243 0.0246 0.41 0.6513 0.9947 3062677 Maybridge4_000908 COC(=O)c1scc(C)c1S(=O)(=O)Nc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J07 compound treatment 0.26 0.0435 0.62 0.265 0.0466 0.78 0.9933 0.9936 1718232 Maybridge4_000909 O=c1n2CCN(Cc3ccccc3)c2nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J08 compound treatment 0.291 0.0745 1.07 0.274 0.0556 0.93 1.4136 0.9978 3062678 Maybridge4_000910 CCOC(=O)c1c[nH]c(=S)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J09 compound treatment 0.265 0.0485 0.69 0.236 0.0176 0.3 0.6997 0.9275 3179334 Maybridge4_000911 Cc1cc2ccccc2c(/N=C/c3cc(Br)cc(Br)c3O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J10 compound treatment 0.25 0.0335 0.48 0.238 0.0196 0.33 0.5717 0.9831 1179240 Maybridge4_000912 COc1ccc(cc1)c2cc(N)nc(N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J11 compound treatment 0.269 0.0525 0.75 0.283 0.0646 1.08 1.2979 0.984 1730849 Maybridge4_000913 Cc1ccc(cc1)S(=O)(=O)N(CCC#N)CC2CCCO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J12 compound treatment 0.274 0.0575 0.82 0.246 0.0276 0.46 0.9094 0.963 3062679 Maybridge4_000914 COC(=O)c1cnc(Nc2ccccc2)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J13 compound treatment 0.04 -0.176 -2.52 0.04 -0.178 -2.99 -3.9022 -0.9964 3179335 Maybridge4_000915 CC(C)c1ccc(NC(=S)Nc2cccc(c2)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J14 compound treatment 0.308 0.0915 1.31 0.314 0.0956 1.6 2.0603 0.9949 1398467 Maybridge4_000916 COC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)c3ncnc4c(C)csc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J15 compound treatment 0.25 0.0335 0.48 0.283 0.0646 1.08 1.1057 0.9327 3062680 Maybridge4_000917 COC(=O)c1ccc(/N=C/N(C)C)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J16 compound treatment 0.282 0.0655 0.94 0.243 0.0246 0.41 0.9547 0.9321 1273229 Maybridge4_000918 COC(=O)c1ccsc1N2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J17 compound treatment 0.098 -0.118 -1.69 0.125 -0.0934 -1.57 -2.3068 -0.9992 1150677 Maybridge4_000919 COc1ccc2Oc3nc(N)c(C#N)c(N)c3C(C(C#N)C#N)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J18 compound treatment 0.274 0.0575 0.82 0.25 0.0316 0.53 0.9568 0.9774 3179336 Maybridge4_000920 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)c3ccccc3OC)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J19 compound treatment 0.295 0.0785 1.12 0.267 0.0486 0.82 1.371 0.9876 3062681 Maybridge4_000921 C1CC1/N=C/c2ccc(cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J20 compound treatment 0.267 0.0505 0.72 0.271 0.0526 0.88 1.1353 0.9951 1209715 Maybridge4_000922 COc1cc(C(=O)NN)c(cc1OC)n2c(C)ccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J21 compound treatment 0.205 -0.0115 -0.16 0.212 -0.00641 -0.11 -0.192 -0.979 3179337 Maybridge4_000923 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Nc2ccsc2C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J22 compound treatment 0.258 0.0415 0.59 0.197 -0.0214 -0.36 0.166 0.2391 3062682 Maybridge4_000924 Cn1nccc1NC(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J23 mock treatment 0.201 -0.0155 -0.22 0.196 -0.0224 -0.38 -0.4224 -0.968 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 J24 mock treatment 0.218 0.00153 0.02 0.215 -0.00341 -0.06 -0.0249 -0.4073 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K01 compound treatment 0.245 0.0285 0.41 0.217 -0.00141 -0.02 0.2719 0.6651 3179338 Maybridge4_000925 CN(C)/C=N/S(=O)(=O)c1c(C)c(C)c(C)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K02 compound treatment 0.24 0.0235 0.34 0.219 5.94E-4 0.01 0.245 0.7277 1131158 Maybridge4_000926 O=S(=O)(N1CCCC1c2cccs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K03 compound treatment 0.242 0.0255 0.37 0.252 0.0336 0.56 0.6569 0.9779 1673268 Maybridge4_000927 COc1ccc(CCn2cnn3c(=O)c4ccccc4nc3c2=O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K04 compound treatment 0.286 0.0695 0.99 0.248 0.0296 0.5 1.0545 0.9485 3062684 Maybridge4_000928 Clc1ccc(Sc2c(C#N)cccc2C#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K05 compound treatment 0.242 0.0255 0.37 0.225 0.00659 0.11 0.3365 0.8818 3179339 Maybridge4_000929 Cc1onc(c1C(=O)NC(=N)N2CCCC2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K06 compound treatment 0.245 0.0285 0.41 0.231 0.0126 0.21 0.438 0.9531 3062686 Maybridge4_000930 NC(=O)N/C(=N\O)/CSc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K07 compound treatment 0.268 0.0515 0.74 0.253 0.0346 0.58 0.9318 0.993 3179340 Maybridge4_000931 Clc1ccc(SCC(=N)NS(=O)(=O)c2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K08 compound treatment 0.288 0.0715 1.02 0.259 0.0406 0.68 1.2053 0.9805 3179341 Maybridge4_000932 CCN(S(=O)(=O)c1ccc(F)cc1)S(=O)(=O)c2c(C)c(C)c(C)c(C)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K09 compound treatment 0.273 0.0565 0.81 0.271 0.0526 0.88 1.196 0.999 3062687 Maybridge4_000933 CS(=O)(=O)Cc1cc(F)cc2COCOc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K10 compound treatment 0.26 0.0435 0.62 0.212 -0.00641 -0.11 0.3643 0.5765 1659719 Maybridge4_000934 Fc1cccc(Cl)c1CSC2=CC(=O)CC(C2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K11 compound treatment 0.317 0.101 1.44 0.306 0.0876 1.47 2.0564 0.9999 3179342 Maybridge4_000935 Cc1c(C)c(C)c(C#CCOC2CCCCO2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K12 compound treatment 0.244 0.0275 0.39 0.258 0.0396 0.66 0.7484 0.9688 3179343 Maybridge4_000936 COc1cccc(OC)c1C(=O)c2cc[n+](C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K13 compound treatment 0.223 0.00653 0.09 0.225 0.00659 0.11 0.1443 0.9964 3062688 Maybridge4_000937 N#Cc1c(oc(c1c2ccc(C#N)cc2)n3cccc3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K14 compound treatment 0.297 0.0805 1.15 0.262 0.0436 0.73 1.3319 0.976 3179344 Maybridge4_000938 Clc1ccc(/C=N/N2CCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K15 compound treatment 0.231 0.0145 0.21 0.299 0.0806 1.35 1.1035 0.8063 3062689 Maybridge4_000939 CN(C)/C=N/c1c(cnn1C)c2nc(cs2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K16 compound treatment 0.243 0.0265 0.38 0.236 0.0176 0.3 0.4771 0.9923 1505900 Maybridge4_000940 Clc1ccc(Cl)c(c1)S(=O)(=O)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K17 compound treatment 0.256 0.0395 0.57 0.251 0.0326 0.55 0.7867 0.9999 3179345 Maybridge4_000941 CN(C1CC2CC1C=C2)C(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K18 compound treatment 0.159 -0.0575 -0.82 0.14 -0.0784 -1.32 -1.5118 -0.9743 1333053 Maybridge4_000942 N1C(Nc2ccccc12)c3c[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K19 compound treatment 0.266 0.0495 0.71 0.246 0.0276 0.46 0.8285 0.9788 3062581 Maybridge4_000943 CC(C)(C)c1cc2N=CN3CCN=C3n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K20 compound treatment 0.241 0.0245 0.35 0.219 5.94E-4 0.01 0.2552 0.7269 3179346 Maybridge4_000944 CN(CCC#N)c1ccc(/C=C/2\CC/C(=C\c3ccc(cc3)N(C)CCC#N)/C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K21 compound treatment 0.208 -0.00847 -0.12 0.192 -0.0264 -0.44 -0.399 -0.8685 3062583 Maybridge4_000945 CC1SCC(CS1)NC(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K22 compound treatment 0.153 -0.0635 -0.91 0.11 -0.108 -1.82 -1.9285 -0.9484 3179347 Maybridge4_000946 COc1ccc(cc1)C2Nc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K23 mock treatment 0.209 -0.00747 -0.11 0.199 -0.0194 -0.33 -0.3059 -0.8923 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 K24 mock treatment 0.218 0.00153 0.02 0.191 -0.0274 -0.46 -0.3098 -0.6727 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L01 compound treatment 0.223 0.00653 0.09 0.235 0.0166 0.28 0.263 0.8953 3062584 Maybridge4_000947 CN1CNC(=NC1)SCc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L02 compound treatment 0.188 -0.0285 -0.41 0.161 -0.0574 -0.96 -0.9692 -0.9266 3179348 Maybridge4_000948 Cn1cc(NC(=O)Nc2ccc(cc2)C(F)(F)F)c(n1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L03 compound treatment 0.215 -0.00147 -0.02 0.215 -0.00341 -0.06 -0.0553 -0.9076 3062585 Maybridge4_000949 CN(C)/N=C(\N)/c1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L04 compound treatment 0.228 0.0115 0.16 0.229 0.0106 0.18 0.2424 0.9993 3179349 Maybridge4_000950 NC(=O)c1sc(cc1NC(=O)c2cccs2)c3ccsc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L05 compound treatment 0.208 -0.00847 -0.12 0.206 -0.0124 -0.21 -0.2329 -0.9668 3062586 Maybridge4_000951 CSC1=NCN(CCCO)CN1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L06 compound treatment 0.274 0.0575 0.82 0.239 0.0206 0.35 0.8263 0.9258 3179350 Maybridge4_000952 FC(F)(F)c1cc(=O)oc2cc(ccc12)N3C(=O)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L07 compound treatment 0.245 0.0285 0.41 0.249 0.0306 0.51 0.6517 0.9935 3062588 Maybridge4_000953 Brc1ccc(CSC2=Nc3ccccc3C(=O)NN2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L08 compound treatment 0.263 0.0465 0.67 0.243 0.0246 0.41 0.7625 0.9736 3179351 Maybridge4_000954 COc1ccc(CC(=O)n2nc(cc2SC)c3ccc(F)cc3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L09 compound treatment 0.235 0.0185 0.27 0.243 0.0246 0.41 0.4793 0.9771 3062590 Maybridge4_000955 COc1ccc(cc1OC)c2sc(/N=C/c3cccs3)c(C#N)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L10 compound treatment 0.237 0.0205 0.29 0.25 0.0316 0.53 0.5826 0.9612 3179352 Maybridge4_000956 COC(=O)c1cnc(nc1C(F)(F)F)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L11 compound treatment 0.24 0.0235 0.34 0.218 -4.06E-4 -0.01 0.2332 0.6926 1310115 Maybridge4_000957 N#CCc1ccc(NC2(CCCCC2)C#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L12 compound treatment 0.263 0.0465 0.67 0.242 0.0236 0.4 0.7506 0.9692 3062591 Maybridge4_000958 FC(F)(F)c1nc(Sc2ccc(Cl)cc2)ncc1C(=O)OCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L13 compound treatment 0.278 0.0615 0.88 0.251 0.0326 0.55 1.0092 0.9738 3179450 Maybridge4_000959 CC1CN(CC(C)O1)C(=S)Nc2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L14 compound treatment 0.256 0.0395 0.57 0.23 0.0116 0.19 0.5374 0.8987 3179451 Maybridge4_000960 Cc1csc2c(ncnc12)N3CCN(CC3)C(=O)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L15 compound treatment 0.239 0.0225 0.32 0.249 0.0306 0.51 0.591 0.9748 3062624 Maybridge4_000961 Clc1ccc2sc(Sc3ccccc3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L16 compound treatment 0.257 0.0405 0.58 0.216 -0.00241 -0.04 0.3814 0.6563 3179452 Maybridge4_000962 C(N1CCC(CC1)Nc2ncnc3sccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L17 compound treatment 0.276 0.0595 0.85 0.212 -0.00641 -0.11 0.5261 0.613 1533957 Maybridge4_000963 CSCCC1NC(=O)NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L18 compound treatment 0.273 0.0565 0.81 0.264 0.0456 0.77 1.1129 0.9996 3179453 Maybridge4_000964 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)Nc3ccc(Cl)cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L19 compound treatment 0.243 0.0265 0.38 0.247 0.0286 0.48 0.6077 0.9932 3062627 Maybridge4_000965 CN(C)c1ccsc1C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L20 compound treatment 0.236 0.0195 0.28 0.23 0.0116 0.19 0.3351 0.9844 3179454 Maybridge4_000966 COc1cc2ncnc(SCC(=O)NN)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L21 compound treatment 0.226 0.00953 0.14 0.254 0.0356 0.6 0.5188 0.8467 3062629 Maybridge4_000967 CNC(=O)c1c(C)csc1NC(=O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L22 compound treatment 0.256 0.0395 0.57 0.215 -0.00341 -0.06 0.3594 0.6324 1534695 Maybridge4_000968 CCN(CC)c1ncnc2sc3CCCCc3c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L23 mock treatment 0.206 -0.0105 -0.15 0.242 0.0236 0.4 0.1741 0.4113 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 L24 mock treatment 0.224 0.00753 0.11 0.195 -0.0234 -0.39 -0.2016 -0.4949 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M01 compound treatment 0.259 0.0425 0.61 0.232 0.0136 0.23 0.5915 0.9104 3062631 Maybridge4_000969 COc1ccc(OC)c(c1)S(=O)(=O)/N=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M02 compound treatment 0.271 0.0545 0.78 0.249 0.0306 0.51 0.9146 0.9794 3179455 Maybridge4_000970 Cc1nn(C)c2SC(=NS(=O)(=O)c12)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M03 compound treatment 0.251 0.0345 0.49 0.242 0.0236 0.4 0.6293 0.994 3062632 Maybridge4_000971 Cn1c(S)nnc1C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M04 compound treatment 0.29 0.0735 1.05 0.237 0.0186 0.31 0.9644 0.879 3179456 Maybridge4_000972 FC(F)(F)c1ccc(CNC(=O)c2ccc(Cl)cc2Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M05 compound treatment 0.246 0.0295 0.42 0.245 0.0266 0.45 0.6143 0.9996 3062633 Maybridge4_000973 CC1CN(CC(C)O1)C(=N)NS(=O)(=O)c2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M06 compound treatment 0.219 0.00253 0.04 0.274 0.0556 0.93 0.6854 0.734 1452088 Maybridge4_000974 CN(C)c1cc(oc(=O)c1Cl)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M07 compound treatment 0.257 0.0405 0.58 0.256 0.0376 0.63 0.8561 0.9991 3062634 Maybridge4_000975 Fc1cccc(Cl)c1CSC(=S)N2CCSCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M08 compound treatment 0.267 0.0505 0.72 0.236 0.0176 0.3 0.7199 0.922 3179457 Maybridge4_000976 CN(C)/C=C/C(=O)C(c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M09 compound treatment 0.299 0.0825 1.18 0.285 0.0666 1.12 1.6251 0.9996 3179458 Maybridge4_000977 Cc1cc(C)n(n1)C2=NCCN2S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M10 compound treatment 0.206 -0.0105 -0.15 0.251 0.0326 0.55 0.2809 0.4953 1473043 Maybridge4_000978 CC(NS(=O)(=O)c1ccc(Oc2cccc(Cl)c2C#N)cc1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M11 compound treatment 0.259 0.0425 0.61 0.246 0.0276 0.46 0.7577 0.9909 3179459 Maybridge4_000979 Cc1ccc(C)n1c2ccsc2COC(=O)Nc3c(C)onc3c4c(F)cccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M12 compound treatment 0.274 0.0575 0.82 0.252 0.0336 0.56 0.9806 0.983 3062636 Maybridge4_000980 CC(=O)n1nccc1c2nccnc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M13 compound treatment 0.277 0.0605 0.87 0.253 0.0346 0.58 1.0228 0.9811 3062637 Maybridge4_000981 Cc1cc(no1)n2cnc(n2)c3cnoc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M14 compound treatment 0.276 0.0595 0.85 0.201 -0.0174 -0.29 0.3955 0.4394 1215853 Maybridge4_000982 COC(=O)c1cccc(NC(=O)NC(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M15 compound treatment 0.216 -4.69E-4 -0.01 0.22 0.00159 0.03 0.0142 0.514 1711378 Maybridge4_000983 Cn1ncc(NCCc2ccncc2)c(Cl)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M16 compound treatment 0.264 0.0475 0.68 0.208 -0.0104 -0.17 0.3572 0.5089 1176335 Maybridge4_000984 CC1CCN(CC1)C(=O)C(C#N)C(=S)Nc2ccc(C)cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M17 compound treatment 0.266 0.0495 0.71 0.239 0.0206 0.35 0.7454 0.9456 3179460 Maybridge4_000985 CN(C)/C=C/C(=O)c1sc(=S)n(CCc2ccc(Cl)cc2)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M18 compound treatment 0.222 0.00553 0.08 0.208 -0.0104 -0.17 -0.0676 -0.3523 1468395 Maybridge4_000986 COc1ccc(cc1OC)c2c(C)n(C)c(C)c2c3ccc(OC)c(OC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M19 compound treatment 0.179 -0.0375 -0.54 0.171 -0.0474 -0.8 -0.9416 -0.9815 3179461 Maybridge4_000987 Cc1ccc(C)n1c2ccccc2C3C=NNC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M20 compound treatment 0.207 -0.00947 -0.14 0.207 -0.0114 -0.19 -0.2311 -0.9856 1563316 Maybridge4_000988 CNc1ccccc1C(=O)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M21 compound treatment 0.211 -0.00547 -0.08 0.228 0.00959 0.16 0.0585 0.3271 3179462 Maybridge4_000989 CC1SCC(CS1)NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M22 compound treatment 0.226 0.00953 0.14 0.198 -0.0204 -0.34 -0.1458 -0.3955 3062639 Maybridge4_000990 Cc1c(C)c(C)c(CN)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M23 mock treatment 0.247 0.0305 0.44 0.209 -0.00941 -0.16 0.1972 0.4246 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 M24 mock treatment 0.221 0.00453 0.06 0.215 -0.00341 -0.06 0.0054 0.0625 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N01 compound treatment 0.218 0.00153 0.02 0.234 0.0156 0.26 0.2006 0.7636 3062690 Maybridge4_000991 CSC1=NCCCN1C(=O)c2ccccc2I 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N02 compound treatment 0.233 0.0165 0.24 0.213 -0.00541 -0.09 0.103 0.4068 3179463 Maybridge4_000992 CCOC(=O)c1cn(CC(=O)NN)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N03 compound treatment 0.221 0.00453 0.06 0.214 -0.00441 -0.07 -0.0065 -0.0657 3062691 Maybridge4_000993 CC(C)(C)N1CNC(=NC1)SCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N04 compound treatment 0.207 -0.00947 -0.14 0.189 -0.0294 -0.49 -0.4448 -0.869 3179464 Maybridge4_000994 NC(=O)c1sc(cc1NC(=O)/C=C/c2ccsc2)c3ccsc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N05 compound treatment 0.241 0.0245 0.35 0.236 0.0176 0.3 0.4569 0.9963 3179465 Maybridge4_000995 COc1cc(/C=N/N(C)C(=S)Nc2cccc(Cl)c2C)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N06 compound treatment 0.176 -0.0405 -0.58 0.199 -0.0194 -0.33 -0.6396 -0.963 3062692 Maybridge4_000996 FC(F)(F)c1c(cnn1c2ccccc2)C(=O)Sc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N07 compound treatment 0.26 0.0435 0.62 0.243 0.0246 0.41 0.7322 0.9801 3179466 Maybridge4_000997 Cc1ccc2N(CCCc2c1)C(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N08 compound treatment 0.289 0.0725 1.04 0.258 0.0396 0.66 1.2035 0.9768 1622973 Maybridge4_000998 CC1CN(CC(C)O1)c2ncnc3c(C)csc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N09 compound treatment 0.248 0.0315 0.45 0.231 0.0126 0.21 0.4684 0.9404 1148536 Maybridge4_000999 COc1cc(cc(OC)c1OC)C(=O)N2CCCN3C2c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N10 compound treatment 0.221 0.00453 0.06 0.234 0.0156 0.26 0.2309 0.8563 3062693 Maybridge4_001000 COC(=O)c1c(C)sc2cc(sc12)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N11 compound treatment 0.26 0.0435 0.62 0.238 0.0196 0.33 0.6728 0.9555 1697786 Maybridge4_001001 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)C2CC(C)CC(C)(C)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N12 compound treatment 0.265 0.0485 0.69 0.217 -0.00141 -0.02 0.4742 0.6827 3062695 Maybridge4_001002 CC1CN(CC(C)O1)c2ncc(C(=O)OCC3CC3)c(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N13 compound treatment 0.298 0.0815 1.17 0.222 0.00359 0.06 0.8673 0.7427 3179467 Maybridge4_001003 CC1CN(CC(C)O1)C(=S)Nc2c(C)cccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N14 compound treatment 0.208 -0.00847 -0.12 0.19 -0.0284 -0.48 -0.4228 -0.8595 3179468 Maybridge4_001004 Cc1csc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(OC(F)(F)F)cc4)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N15 compound treatment 0.219 0.00253 0.04 0.22 0.00159 0.03 0.0445 0.9889 3062698 Maybridge4_001005 CN(C)C(=O)Oc1ccc2nnc3ccnn3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N16 compound treatment 0.267 0.0505 0.72 0.292 0.0736 1.24 1.3845 0.9674 1412351 Maybridge4_001006 C1CCN(C1)c2ncnc3sccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N17 compound treatment 0.248 0.0315 0.45 0.257 0.0386 0.65 0.7769 0.9843 3179469 Maybridge4_001007 CC(C)CC1NC(=O)N(C)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N18 compound treatment 0.276 0.0595 0.85 0.222 0.00359 0.06 0.6448 0.7553 1428548 Maybridge4_001008 Cn1nccc1N2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N19 compound treatment 0.268 0.0515 0.74 0.214 -0.00441 -0.07 0.4689 0.633 3179470 Maybridge4_001009 C/C(=N\O)/CSC(=O)c1c(C)onc1c2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N20 compound treatment 0.254 0.0375 0.54 0.236 0.0176 0.3 0.5884 0.9604 3062700 Maybridge4_001010 CNC(=S)NCc1ccco1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N21 compound treatment 0.251 0.0345 0.49 0.271 0.0526 0.88 0.9734 0.9624 3179471 Maybridge4_001011 Cn1ccc(NC(=O)Nc2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N22 compound treatment 0.31 0.0935 1.34 0.241 0.0226 0.38 1.2141 0.8731 1103188 Maybridge4_001012 C(CNc1ncnc2sc3CCCCc3c12)CN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N23 mock treatment 0.244 0.0275 0.39 0.208 -0.0104 -0.17 0.155 0.3597 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 N24 mock treatment 0.22 0.00353 0.05 0.229 0.0106 0.18 0.1614 0.8734 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O01 compound treatment 0.234 0.0175 0.25 0.193 -0.0254 -0.43 -0.1242 -0.2511 3062702 Maybridge4_001013 CN(C)/C=N/S(=O)(=O)c1ccc(Cl)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O02 compound treatment 0.241 0.0245 0.35 0.182 -0.0364 -0.61 -0.184 -0.2611 3179472 Maybridge4_001014 Cc1nn(C)c2SC(=NS(=O)(=O)c12)SCc3c(F)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O03 compound treatment 0.21 -0.00647 -0.09 0.251 0.0326 0.55 0.3214 0.5793 3062703 Maybridge4_001015 CN(C)/C=C/C(=O)c1cc(F)ccc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O04 compound treatment 0.245 0.0285 0.41 0.215 -0.00341 -0.06 0.2481 0.6022 3179473 Maybridge4_001016 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)OC2CCSC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O05 compound treatment 0.256 0.0395 0.57 0.265 0.0466 0.78 0.9528 0.9873 3062704 Maybridge4_001017 CC1CN(CC(C)O1)C(=N)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O06 compound treatment 0.253 0.0365 0.52 0.274 0.0556 0.93 1.0293 0.9625 3179474 Maybridge4_001018 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2ccn[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O07 compound treatment 0.273 0.0565 0.81 0.256 0.0376 0.63 1.0179 0.9925 3179571 Maybridge4_001019 Fc1cccc(Cl)c1CCNC(=O)NC(=O)Cc2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O08 compound treatment 0.22 0.00353 0.05 0.207 -0.0114 -0.19 -0.0997 -0.5033 3062705 Maybridge4_001020 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)S(=O)(=O)n2cccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O09 compound treatment 0.205 -0.0115 -0.16 0.212 -0.00641 -0.11 -0.192 -0.979 3179572 Maybridge4_001021 CS/C(=N/S(=O)(=O)c1ccccc1)/NCCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O10 compound treatment 0.186 -0.0305 -0.44 0.226 0.00759 0.13 -0.218 -0.4802 1316388 Maybridge4_001022 Clc1ccc(cc1)S(=O)(=O)NCC2CN(Cc3ccccc3)CN(Cc4ccccc4)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O11 compound treatment 0.231 0.0145 0.21 0.221 0.00259 0.04 0.1778 0.837 1687690 Maybridge4_001023 Clc1cc(Cl)cc(OC(=O)C2(CC3CC4CC(C3)C2)C4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O12 compound treatment 0.266 0.0495 0.71 0.235 0.0166 0.28 0.6979 0.9168 3063461 Maybridge4_001024 Cc1nc(CSCc2ccc(Cl)cc2Cl)cs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O13 compound treatment 0.176 -0.0405 -0.58 0.224 0.00559 0.09 -0.3429 -0.5848 1553397 Maybridge4_001025 O=C(Nc1ccccc1)OC(CSc2ccccn2)CSc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O14 compound treatment 0.192 -0.0245 -0.35 0.197 -0.0214 -0.36 -0.5015 -0.9999 1170892 Maybridge4_001026 COC(=O)c1cccc(NC(=O)Nc2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O15 compound treatment 0.218 0.00153 0.02 0.205 -0.0134 -0.23 -0.1436 -0.6353 1387636 Maybridge4_001027 CN(C)c1cccc(N(C)C)c1CNS(=O)(=O)c2cc(C)c(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O16 compound treatment 0.213 -0.00347 -0.05 0.192 -0.0264 -0.44 -0.3485 -0.7814 1136580 Maybridge4_001028 Clc1ccccc1NC(=S)C(C#N)C(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O17 compound treatment 0.19 -0.0265 -0.38 0.177 -0.0414 -0.69 -0.7591 -0.9592 3063462 Maybridge4_001029 CN(C1CC2CC1C=C2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O18 compound treatment 0.231 0.0145 0.21 0.194 -0.0244 -0.41 -0.1427 -0.3106 1238489 Maybridge4_001030 Cc1cc2NC(=O)c3ccccc3C(=Nc2cc1C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O19 compound treatment 0.206 -0.0105 -0.15 0.202 -0.0164 -0.28 -0.3006 -0.959 3063463 Maybridge4_001031 CN(C)/C=N/c1ccccc1C2C=NNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O20 compound treatment 0.222 0.00553 0.08 0.225 0.00659 0.11 0.1342 0.9865 3179573 Maybridge4_001032 S=C1NCCN1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O21 compound treatment 0.229 0.0125 0.18 0.194 -0.0244 -0.41 -0.1629 -0.3643 1607454 Maybridge4_001033 CC1=C(N2CCOCC2)C(=NCCN1)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O22 compound treatment 0.212 -0.00447 -0.06 0.23 0.0116 0.19 0.0924 0.4511 1293246 Maybridge4_001034 Cc1nc2ccccc2n1C3CC(=O)N(C3=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O23 mock treatment 0.202 -0.0145 -0.21 0.217 -0.00141 -0.02 -0.163 -0.7827 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 O24 mock treatment 0.213 -0.00347 -0.05 0.229 0.0106 0.18 0.0906 0.491 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P01 compound treatment 0.208 -0.00847 -0.12 0.206 -0.0124 -0.21 -0.2329 -0.9668 1354193 Maybridge4_001035 OCCN1CNC(=S)NC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P02 compound treatment 0.047 -0.169 -2.42 0.049 -0.169 -2.84 -3.7246 -0.9968 3179574 Maybridge4_001036 FC(F)(F)c1cc(NC(=O)N/C=C/c2ccsc2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P03 compound treatment 0.219 0.00253 0.04 0.217 -0.00141 -0.02 0.0089 0.2062 3063464 Maybridge4_001037 C(SC1=NCN(Cc2ccccc2)CN1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P04 compound treatment 0.229 0.0125 0.18 0.21 -0.00841 -0.14 0.027 0.1183 3179575 Maybridge4_001038 COC(=O)c1sccc1N2C(=O)C=C(C)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P05 compound treatment 0.062 -0.154 -2.21 0.047 -0.171 -2.88 -3.5966 -0.9915 3179576 Maybridge4_001039 CN(/N=C/c1ccccn1)C(=S)Nc2ccc(C)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P06 compound treatment 0.224 0.00753 0.11 0.216 -0.00241 -0.04 0.0476 0.4139 1429512 Maybridge4_001040 CCCc1c(NC(=O)Nc2ccc(Cl)cc2Cl)cnn1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P07 compound treatment 0.244 0.0275 0.39 0.233 0.0146 0.24 0.4517 0.9739 1160255 Maybridge4_001041 N#CC1(CCCCCC1)NC(Cc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P08 compound treatment 0.228 0.0115 0.16 0.245 0.0266 0.45 0.4322 0.9084 1344462 Maybridge4_001042 CC(C)Nc1ncnc2c(C)csc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P09 compound treatment 0.229 0.0125 0.18 0.218 -4.06E-4 -0.01 0.1219 0.6797 3179577 Maybridge4_001043 COc1cc(cc(OC)c1OC)C2NN=C3C2N4CCC3CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P10 compound treatment 0.242 0.0255 0.37 0.275 0.0566 0.95 0.9299 0.9138 3063465 Maybridge4_001044 FC(F)(F)c1ccc(NC(=O)C2CCc3ccccc3O2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P11 compound treatment 0.217 5.31E-4 0.01 0.23 0.0116 0.19 0.143 0.7342 1463450 Maybridge4_001045 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)Cc2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P12 compound treatment 0.259 0.0425 0.61 0.217 -0.00141 -0.02 0.4135 0.6792 3179578 Maybridge4_001046 CSc1cc(nn1S(=O)(=O)c2cccc(c2)C(F)(F)F)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P13 compound treatment 0.257 0.0405 0.58 0.263 0.0446 0.75 0.9392 0.992 3063466 Maybridge4_001047 COc1cccc(NC(=S)N(CCC#N)/N=C/c2ccc3OCOc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P14 compound treatment 0.238 0.0215 0.31 0.229 0.0106 0.18 0.3435 0.9659 1234970 Maybridge4_001048 Cc1csc2ncnc(N3CCN(CC3)C(=S)Nc4ccc(F)cc4F)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P15 compound treatment 0.22 0.00353 0.05 0.203 -0.0154 -0.26 -0.1471 -0.5584 1069786 Maybridge4_001049 NNC(=O)OC1(CC2CC3CC(C2)C1)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P16 compound treatment 0.27 0.0535 0.77 0.182 -0.0364 -0.61 0.1094 0.1116 3179579 Maybridge4_001050 CCOC(=O)c1cnc(Sc2ccc(F)c(Cl)c2)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P17 compound treatment 0.23 0.0135 0.19 0.203 -0.0154 -0.26 -0.046 -0.1424 3063467 Maybridge4_001051 Sc1nc(ccc1C#N)c2ccc3OCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P18 compound treatment 0.265 0.0485 0.69 0.226 0.00759 0.13 0.581 0.8232 1377109 Maybridge4_001052 CCOC(=O)c1cc(=O)c2cc(Cl)ccc2o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P19 compound treatment 0.27 0.0535 0.77 0.238 0.0196 0.33 0.774 0.9288 1695486 Maybridge4_001053 CC1CCCN(C1)c2ccc3nncn3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P20 compound treatment 0.258 0.0415 0.59 0.222 0.00359 0.06 0.4627 0.7749 3063468 Maybridge4_001054 Cn1ncc(Br)c1NC(=O)CSc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P21 compound treatment 0.237 0.0205 0.29 0.259 0.0406 0.68 0.6894 0.9292 3179580 Maybridge4_001055 COC(=O)c1sccc1NS(=O)(=O)c2ccc(F)cc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P22 compound treatment 0.236 0.0195 0.28 0.213 -0.00541 -0.09 0.1334 0.4541 1127720 Maybridge4_001056 CCC(C)Nc1ncnc2cc(OC)c(OC)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P23 mock treatment 0.26 0.0435 0.62 0.235 0.0166 0.28 0.6372 0.9342 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2051 P24 mock treatment 0.201 -0.0155 -0.22 0.235 0.0166 0.28 0.0405 0.1138 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A01 compound treatment 0.218 1.88E-4 0.0 0.232 0.0181 0.3 0.2163 0.7133 1118682 Maybridge4_001057 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A02 compound treatment 0.233 0.0152 0.22 0.222 0.00806 0.14 0.2493 0.9741 1260001 Maybridge4_001058 O=C(CC1(CC2CC3CC(C2)C1)C3)NC4CCN(Cc5ccccc5)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A03 compound treatment 0.239 0.0212 0.3 0.258 0.0441 0.74 0.7372 0.9224 3063469 Maybridge4_001059 Cn1ncc(C(=O)Sc2ccc(Cl)cc2)c1n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A04 compound treatment 0.241 0.0232 0.33 0.222 0.00806 0.14 0.3302 0.9218 3179581 Maybridge4_001060 Oc1cc(nc(SCC(=O)c2ccc(Cl)s2)n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A05 compound treatment 0.187 -0.0308 -0.44 0.225 0.0111 0.19 -0.1804 -0.3771 3063470 Maybridge4_001061 FC(F)(F)c1ccnc(Sc2ccccc2NC(=O)Nc3ccccc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A06 compound treatment 0.238 0.0202 0.29 0.255 0.0411 0.69 0.6915 0.9254 3179582 Maybridge4_001062 CC(C)(C)c1cc(C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F)n(Cc4ccc(F)cc4)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A07 compound treatment 0.253 0.0352 0.5 0.236 0.0221 0.37 0.6177 0.9886 3063471 Maybridge4_001063 CN(/N=C/c1ncc(cc1Cl)C(F)(F)F)C(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A08 compound treatment 0.243 0.0252 0.36 0.222 0.00806 0.14 0.3504 0.9106 3179583 Maybridge4_001064 COC(=O)c1ccc(n1C)S(=O)(=O)NCCNc2cccc(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A09 compound treatment 0.185 -0.0328 -0.47 0.211 -0.00294 -0.05 -0.3667 -0.7771 3063472 Maybridge4_001065 Cc1cccc(c1)n2c(CC#N)n[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A10 compound treatment 0.197 -0.0208 -0.3 0.234 0.0201 0.34 0.0276 0.0614 1646442 Maybridge4_001066 Cc1ccc2N(CC(=O)N(C3CCCCC3)c4ccccc4)CCCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A11 compound treatment 0.239 0.0212 0.3 0.211 -0.00294 -0.05 0.1794 0.5844 1595838 Maybridge4_001067 COC(=O)c1sccc1S(=O)(=O)Nc2cc(OC)c(OC)cc2C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A12 compound treatment 0.258 0.0402 0.57 0.239 0.0251 0.42 0.7039 0.9882 3179584 Maybridge4_001068 FC(F)(F)c1ccc(N2CCc3ccccc3C2)c(NC(=O)c4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A13 compound treatment 0.209 -0.00881 -0.13 0.21 -0.00394 -0.07 -0.1359 -0.9546 3063473 Maybridge4_001069 FC(F)(F)C1=NCCN(C=C1)S(=O)(=O)c2ccc(CNC(=O)c3ccccc3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A14 compound treatment 0.225 0.00719 0.1 0.195 -0.0189 -0.32 -0.1521 -0.4552 1536339 Maybridge4_001070 OC(=O)COCC(=O)N1CCCN(CC1)c2nc3ccc(Cl)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A15 compound treatment 0.207 -0.0108 -0.15 0.219 0.00506 0.08 -0.0493 -0.2793 1391994 Maybridge4_001071 CCOC(=O)C1CCN(CC1)c2ncnc3cc(OC)c(OC)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A16 compound treatment 0.208 -0.00981 -0.14 0.208 -0.00594 -0.1 -0.1697 -0.9859 1501197 Maybridge4_001072 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCC3CCN(CC3)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A17 compound treatment 0.22 0.00219 0.03 0.201 -0.0129 -0.22 -0.1314 -0.599 1440783 Maybridge4_001073 COc1cc(cc(OC)c1OC)C(CC(=O)O)CC(=O)N2CCC(CC2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A18 compound treatment 0.184 -0.0338 -0.48 0.212 -0.00194 -0.03 -0.365 -0.753 1175173 Maybridge4_001074 CC(C)(C)c1ccc(cc1)c2noc(n2)c3ccc4OCCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A19 compound treatment 0.217 -8.12E-4 -0.01 0.205 -0.00894 -0.15 -0.1143 -0.7596 1213784 Maybridge4_001075 NC(=O)C1CCN(CN2C(=O)c3ccccc3C2=O)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A20 compound treatment 0.199 -0.0188 -0.27 0.224 0.0101 0.17 -0.0709 -0.223 1134687 Maybridge4_001076 OC(=O)c1nccnc1C(=O)Nc2ccc(cc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A21 compound treatment 0.042 -0.176 -2.51 0.046 -0.168 -2.82 -3.7713 -0.9984 3063474 Maybridge4_001077 FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A22 compound treatment 0.22 0.00219 0.03 0.22 0.00606 0.1 0.0941 0.8837 3179585 Maybridge4_001078 COc1ccccc1N2CCN(CC2)C(=O)c3cnn(c3C)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A23 mock treatment 0.215 -0.00281 -0.04 0.178 -0.0359 -0.6 -0.455 -0.7526 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 A24 mock treatment 0.209 -0.00881 -0.13 0.192 -0.0219 -0.37 -0.3495 -0.898 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B01 compound treatment 0.233 0.0152 0.22 0.238 0.0241 0.4 0.4392 0.9577 1733246 Maybridge4_001079 Cc1cnc(cn1)C(=O)Nc2nnn[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B02 compound treatment 0.212 -0.00581 -0.08 0.242 0.0281 0.47 0.2743 0.5734 1403239 Maybridge4_001080 NC(=O)C1CCN(CC(O)COc2ccc(cc2)c3csnn3)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B03 compound treatment 0.228 0.0102 0.15 0.229 0.0151 0.25 0.2818 0.9657 1480432 Maybridge4_001081 COc1ccc(cc1OC)S(=O)(=O)NCCN2CCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B04 compound treatment 0.244 0.0262 0.37 0.231 0.0171 0.29 0.4674 0.9912 3179682 Maybridge4_001082 Cc1ccsc1CNC(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B05 compound treatment 0.243 0.0252 0.36 0.23 0.0161 0.27 0.4454 0.9898 1539091 Maybridge4_001083 OC(=O)c1cc(ccc1O)S(=O)(=O)NCCN2CCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B06 compound treatment 0.242 0.0242 0.35 0.221 0.00706 0.12 0.3285 0.8981 1590468 Maybridge4_001084 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B07 compound treatment 0.237 0.0192 0.27 0.242 0.0281 0.47 0.5271 0.967 1660094 Maybridge4_001085 Cc1nn(nc1C(=O)NC2CCS(=O)(=O)C2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B08 compound treatment 0.219 0.00119 0.02 0.224 0.0101 0.17 0.1314 0.7743 1742612 Maybridge4_001086 COc1ccc(SCC(=O)NCc2ccc3OCOc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B09 compound treatment 0.247 0.0292 0.42 0.263 0.0491 0.82 0.8775 0.9504 3179683 Maybridge4_001087 CCOC(=O)c1c(NC(=O)NC(C)(C)C)sc2CN(C)CCc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B10 compound treatment 0.234 0.0162 0.23 0.21 -0.00394 -0.07 0.117 0.4859 1477333 Maybridge4_001088 Cc1cc(NC(=O)C2CCN(CC2)C(=O)OCc3ccccc3)n(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B11 compound treatment 0.238 0.0202 0.29 0.226 0.0121 0.2 0.3473 0.9849 1603040 Maybridge4_001089 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccc5OCCc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B12 compound treatment 0.215 -0.00281 -0.04 0.218 0.00406 0.07 0.0198 0.2497 3179684 Maybridge4_001090 Cn1c(SCC(=O)c2ccc3OCCOc3c2)nnc1c4ccc5ccccc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B13 compound treatment 0.239 0.0212 0.3 0.239 0.0251 0.42 0.5117 0.9871 3063475 Maybridge4_001091 CN(C(=O)c1scc(c1C)S(=O)(=O)c2ccc(Cl)cc2)c3nnc(s3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B14 compound treatment 0.209 -0.00881 -0.13 0.179 -0.0349 -0.59 -0.5038 -0.8399 3179685 Maybridge4_001092 CCOC(=O)c1c(C)n(c(C)c1/C=C/2\C(=O)Nc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B15 compound treatment 0.245 0.0272 0.39 0.223 0.00906 0.15 0.3825 0.9161 1321807 Maybridge4_001093 Cn1nc(cc1C(=O)NN2CCOCC2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B16 compound treatment 0.246 0.0282 0.4 0.212 -0.00194 -0.03 0.2621 0.648 3179686 Maybridge4_001094 Cc1ccc(cc1)S(=O)(=O)CCSc2nccc(n2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B17 compound treatment 0.242 0.0242 0.35 0.219 0.00506 0.08 0.3047 0.8554 1191907 Maybridge4_001095 O=C1NCCN1CCNC(=S)NC2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B18 compound treatment 0.236 0.0182 0.26 0.219 0.00506 0.08 0.244 0.8917 1709557 Maybridge4_001096 COc1ccc(OCC(O)CNC(=O)c2c(C)onc2c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B19 compound treatment 0.243 0.0252 0.36 0.24 0.0261 0.44 0.5641 0.9954 1259000 Maybridge4_001097 CCCc1c(cnn1c2ccccc2)C(=O)N(Cc3cccs3)Cc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B20 compound treatment 0.234 0.0162 0.23 0.227 0.0131 0.22 0.3188 0.9996 1607244 Maybridge4_001098 O=C(N1CCN(CCN2CCOCC2)CC1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B21 compound treatment 0.24 0.0222 0.32 0.231 0.0171 0.29 0.4269 0.9987 1594969 Maybridge4_001099 CCCc1c(cnn1c2ccccc2)C(=O)Nc3nc[nH]n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B22 compound treatment 0.223 0.00519 0.07 0.247 0.0331 0.55 0.4449 0.7946 3063476 Maybridge4_001100 Clc1ccc(Sc2cccc(Cl)c2Cn3cccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B23 mock treatment 0.244 0.0262 0.37 0.225 0.0111 0.19 0.3962 0.9476 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 B24 mock treatment 0.233 0.0152 0.22 0.197 -0.0169 -0.28 -0.0474 -0.1325 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C01 compound treatment 0.233 0.0152 0.22 0.223 0.00906 0.15 0.2612 0.9848 3179687 Maybridge4_001101 Cc1cc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C=CC3=O)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C02 compound treatment 0.206 -0.0118 -0.17 0.208 -0.00594 -0.1 -0.1899 -0.9683 1404378 Maybridge4_001102 OC1(CCN(CC1)C(=O)CC2(CC3CC4CC(C3)C2)C4)c5ccc(Cl)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C03 compound treatment 0.201 -0.0168 -0.24 0.218 0.00406 0.07 -0.1218 -0.4874 1249628 Maybridge4_001103 COc1ccc(cc1OC)C(=O)N2CCN(CC2)c3ncnc4cc(sc34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C04 compound treatment 0.224 0.00619 0.09 0.224 0.0101 0.17 0.182 0.9545 3063496 Maybridge4_001104 Fc1ccc(NC(=O)NCc2nc(no2)c3ccc(cc3)C(F)(F)F)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C05 compound treatment 0.236 0.0182 0.26 0.207 -0.00694 -0.12 0.1016 0.3565 3063497 Maybridge4_001105 OC(CSc1ccccc1NC(=O)/C=C\C(=O)O)Cn2ccc(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C06 compound treatment 0.228 0.0102 0.15 0.216 0.00206 0.03 0.1275 0.8514 3063498 Maybridge4_001106 Cn1nc(c(c1NC(=O)c2nccnc2C(=O)O)c3cccc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C07 compound treatment 0.222 0.00419 0.06 0.227 0.0131 0.22 0.1974 0.8685 3179688 Maybridge4_001107 CN(/N=C/c1ncc(cc1Cl)C(F)(F)F)C(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C08 compound treatment 0.21 -0.00781 -0.11 0.227 0.0131 0.22 0.076 0.3089 3063499 Maybridge4_001108 FC(F)(F)C1=NCCN(C=C1)C(=O)C2CCN(CC2)c3nccc(n3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C09 compound treatment 0.184 -0.0338 -0.48 0.21 -0.00394 -0.07 -0.3887 -0.7963 1483010 Maybridge4_001109 COc1ccc(CN(Cc2cccn2C)C(=O)c3cc4cc(OC)ccc4[nH]3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C10 compound treatment 0.178 -0.0398 -0.57 0.101 -0.113 -1.9 -1.743 -0.8807 1408441 Maybridge4_001110 COC(=O)c1sc(cc1NC(=O)COCC(=O)O)c2ccc(cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C11 compound treatment 0.228 0.0102 0.15 0.214 6.25E-5 0.0 0.1038 0.7122 3179689 Maybridge4_001111 FC(F)(F)c1cc(N2CCN(CC2)C(=O)C3CCC3)c4ccccc4n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C12 compound treatment 0.173 -0.0448 -0.64 0.227 0.0131 0.22 -0.2982 -0.4402 3063500 Maybridge4_001112 FC(F)(F)c1oc(cc1C(=O)NCc2cccs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C13 compound treatment 0.231 0.0132 0.19 0.207 -0.00694 -0.12 0.051 0.2303 3179690 Maybridge4_001113 CCC(=O)N(C)c1nc(cs1)c2ccc(Cl)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C14 compound treatment 0.195 -0.0228 -0.33 0.222 0.00806 0.14 -0.135 -0.3823 3179691 Maybridge4_001114 Fc1ccc(cc1)S(=O)(=O)Nc2ccccc2NC3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C15 compound treatment 0.199 -0.0188 -0.27 0.204 -0.00994 -0.17 -0.3082 -0.9735 1317474 Maybridge4_001115 COc1cccc(Cl)c1NC(=O)N2CCN(CC2)c3cc(C)nc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C16 compound treatment 0.218 1.88E-4 0.0 0.175 -0.0389 -0.65 -0.4602 -0.7042 3179692 Maybridge4_001116 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)C(F)(F)F)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C17 compound treatment 0.214 -0.00381 -0.05 0.215 0.00106 0.02 -0.026 -0.4523 1139184 Maybridge4_001117 COc1ccc(CC2CCC3(CC2)NC(=O)c4ccccc4O3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C18 compound treatment 0.227 0.00919 0.13 0.22 0.00606 0.1 0.1649 0.992 1486833 Maybridge4_001118 COC(=O)c1cc(oc1C)S(=O)(=O)NCC2CN(Cc3ccccc3)CN(Cc4ccccc4)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C19 compound treatment 0.231 0.0132 0.19 0.214 6.25E-5 0.0 0.1341 0.711 1538683 Maybridge4_001119 OC1(CCN(CN2C(=O)c3ccccc3C2=O)CC1)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C20 compound treatment 0.207 -0.0108 -0.15 0.2 -0.0139 -0.23 -0.2748 -0.9798 3063501 Maybridge4_001120 OC(=O)/C=C/C(=O)Nc1ccc(nc1N2CCOCC2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C21 compound treatment 0.188 -0.0298 -0.43 0.226 0.0121 0.2 -0.1584 -0.3355 1658419 Maybridge4_001121 NC(=O)C1CCN(CC(O)CSc2ccc(F)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C22 compound treatment 0.198 -0.0198 -0.28 0.062 -0.152 -2.55 -2.0036 -0.7809 1233858 Maybridge4_001122 CS(=O)(=O)CS(=O)(=O)Nc1ccc2OCCOc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C23 mock treatment 0.2 -0.0178 -0.25 0.198 -0.0159 -0.27 -0.3693 -0.9997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 C24 mock treatment 0.212 -0.00581 -0.08 0.185 -0.0289 -0.49 -0.4022 -0.8163 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D01 compound treatment 0.216 -0.00181 -0.03 0.231 0.0171 0.29 0.1842 0.6405 1662148 Maybridge4_001123 Cc1nc(cn1C)S(=O)(=O)NC2CCS(=O)(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D02 compound treatment 0.22 0.00219 0.03 0.213 -9.38E-4 -0.02 0.011 0.314 1341736 Maybridge4_001124 CCN(CC)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D03 compound treatment 0.257 0.0392 0.56 0.243 0.0291 0.49 0.7413 0.9976 3063502 Maybridge4_001125 Cn1cnc(c1)S(=O)(=O)NCC2CCN(CC2)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D04 compound treatment 0.218 1.88E-4 0.0 0.226 0.0121 0.2 0.1451 0.7164 3179693 Maybridge4_001126 Cc1nnc(Sc2nc3ccc(Cl)cc3s2)n1c4ccc5OCCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D05 compound treatment 0.257 0.0392 0.56 0.21 -0.00394 -0.07 0.3496 0.6194 1259497 Maybridge4_001127 O=C1NCCN1CCNS(=O)(=O)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D06 compound treatment 0.249 0.0312 0.45 0.223 0.00906 0.15 0.423 0.8975 1281709 Maybridge4_001128 OC(=O)CSCC(=O)N1CCN(Cc2ccc3OCOc3c2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D07 compound treatment 0.162 -0.0558 -0.8 0.211 -0.00294 -0.05 -0.5994 -0.7493 1146339 Maybridge4_001129 CCCCc1ccc(cc1)n2c(coc2=O)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D08 compound treatment 0.266 0.0482 0.69 0.282 0.0681 1.14 1.2952 0.9707 1522891 Maybridge4_001130 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3cn(C)cn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D09 compound treatment 0.226 0.00819 0.12 0.263 0.0491 0.82 0.6651 0.7996 3063503 Maybridge4_001131 FC(F)(F)c1nn2c(=O)cc([nH]c2c1c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D10 compound treatment 0.265 0.0472 0.67 0.275 0.0611 1.02 1.202 0.9795 1088065 Maybridge4_001132 Cc1cc(C(=O)Nc2ccccc2)c(C)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D11 compound treatment 0.27 0.0522 0.75 0.265 0.0511 0.86 1.1339 0.9976 1383227 Maybridge4_001133 O=C(OCCn1ncc2ccccc2c1=O)c3ccc4OCCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D12 compound treatment 0.234 0.0162 0.23 0.278 0.0641 1.08 0.924 0.8401 1524796 Maybridge4_001134 Cc1ccc(cc1)c2cc(Cc3ccccc3)c(=O)[nH]n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D13 compound treatment 0.234 0.0162 0.23 0.267 0.0531 0.89 0.7935 0.8623 1531019 Maybridge4_001135 Cc1c(csc1C(=O)N(Cc2ccccc2)Cc3cccnc3)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D14 compound treatment 0.272 0.0542 0.78 0.253 0.0391 0.66 1.0117 0.9965 3063504 Maybridge4_001136 OC(=O)c1nccnc1C(=O)Nc2ccc(CC#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D15 compound treatment 0.273 0.0552 0.79 0.26 0.0461 0.77 1.1049 0.9999 1469748 Maybridge4_001137 CSc1nsc(SC)c1C(=O)NN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D16 compound treatment 0.288 0.0702 1.0 0.256 0.0421 0.71 1.2091 0.9852 3063505 Maybridge4_001138 Fc1ccc(cc1)S(=O)(=O)CCSc2nccc(n2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D17 compound treatment 0.282 0.0642 0.92 0.276 0.0621 1.04 1.3858 0.998 3179791 Maybridge4_001139 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccc3COC(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D18 compound treatment 0.211 -0.00681 -0.1 0.237 0.0231 0.39 0.2048 0.5131 3179792 Maybridge4_001140 COc1ccc(OCC(O)CNC(=O)c2ccc(OC(F)(F)F)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D19 compound treatment 0.241 0.0232 0.33 0.242 0.0281 0.47 0.5676 0.9853 1658181 Maybridge4_001141 CCCc1c(cnn1c2ccccc2)C(=O)NCc3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D20 compound treatment 0.242 0.0242 0.35 0.216 0.00206 0.03 0.2691 0.774 1302806 Maybridge4_001142 CCOC(=O)N1CCC(CC1)NC(=O)Nc2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D21 compound treatment 0.242 0.0242 0.35 0.218 0.00406 0.07 0.2929 0.8305 1417198 Maybridge4_001143 COc1cccc2n(C)nc(NC(=O)CCC(=O)O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D22 compound treatment 0.203 -0.0148 -0.21 0.246 0.0321 0.54 0.2307 0.3989 1130087 Maybridge4_001144 COc1ccc(OCC(O)CNC(=O)Nc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D23 mock treatment 0.232 0.0142 0.2 0.237 0.0231 0.39 0.4172 0.9546 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 D24 mock treatment 0.209 -0.00881 -0.13 0.212 -0.00194 -0.03 -0.1121 -0.8613 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E01 compound treatment 0.236 0.0182 0.26 0.211 -0.00294 -0.05 0.1491 0.5631 1356815 Maybridge4_001145 Cn1ncc2c(NN3C(=O)CCC3=O)ncnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E02 compound treatment 0.236 0.0182 0.26 0.216 0.00206 0.03 0.2084 0.7942 3063506 Maybridge4_001146 FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)N3CCN(Cc4ccccc4)CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E03 compound treatment 0.183 -0.0348 -0.5 0.198 -0.0159 -0.27 -0.5412 -0.9575 3179793 Maybridge4_001147 COC(=O)c1sc(cc1NS(=O)(=O)c2ccc(C)cc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E04 compound treatment 0.046 -0.172 -2.46 0.045 -0.169 -2.84 -3.7427 -0.9975 1593578 Maybridge4_001148 Cc1noc(C)c1n2sc(=O)n(CC3CC3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E05 compound treatment 0.212 -0.00581 -0.08 0.197 -0.0169 -0.28 -0.2598 -0.8772 1366685 Maybridge4_001149 OC(CSc1ccccc1NC(=O)c2ccc(Cl)cc2)Cn3ccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E06 compound treatment 0.169 -0.0488 -0.7 0.202 -0.0119 -0.2 -0.6354 -0.8747 1718437 Maybridge4_001150 CCCCc1ccc(NC(=O)N2CCN(CC2)c3cc(C)nc4ccccc34)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E07 compound treatment 0.215 -0.00281 -0.04 0.217 0.00306 0.05 0.0079 0.121 3063507 Maybridge4_001151 CNC(=S)NC1CC2CCC1C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E08 compound treatment 0.042 -0.176 -2.51 0.041 -0.173 -2.9 -3.8306 -0.9974 1663721 Maybridge4_001152 Fc1ccc(cc1Cl)n2sc(=O)n(C3Cc4ccccc4C3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E09 compound treatment 0.287 0.0692 0.99 0.281 0.0671 1.13 1.4957 0.9979 3063508 Maybridge4_001153 Cc1nnsc1c2nc(cs2)c3ccc(Cl)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E10 compound treatment 0.233 0.0152 0.22 0.259 0.0451 0.76 0.6884 0.8748 1128288 Maybridge4_001154 COC(=O)c1ccc(n1C)S(=O)(=O)N(Cc2ccccc2)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E11 compound treatment 0.254 0.0362 0.52 0.217 0.00306 0.05 0.4024 0.7735 1703913 Maybridge4_001155 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2cccc(c2)c3cnco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E12 compound treatment 0.04 -0.178 -2.54 0.043 -0.171 -2.87 -3.8271 -0.9982 1704448 Maybridge4_001156 Cc1cccc(Cl)c1n2sc(=O)n(CC3CC3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E13 compound treatment 0.252 0.0342 0.49 0.261 0.0471 0.79 0.9043 0.9734 1205718 Maybridge4_001157 CN(C(=O)C1CCCCC1)c2nc(cs2)c3ccc(Cl)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E14 compound treatment 0.26 0.0422 0.6 0.211 -0.00294 -0.05 0.3918 0.6472 3179794 Maybridge4_001158 Cc1ccc(OCC(O)CNc2ccc(Br)c(c2)C(F)(F)F)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E15 compound treatment 0.211 -0.00681 -0.1 0.237 0.0231 0.39 0.2048 0.5131 3063509 Maybridge4_001159 OC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E16 compound treatment 0.198 -0.0198 -0.28 0.249 0.0351 0.59 0.2157 0.3303 1390204 Maybridge4_001160 Cn1cnc(c1)S(=O)(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E17 compound treatment 0.204 -0.0138 -0.2 0.247 0.0331 0.55 0.2527 0.429 1537127 Maybridge4_001161 COc1ccccc1NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E18 compound treatment 0.211 -0.00681 -0.1 0.218 0.00406 0.07 -0.0207 -0.174 1388804 Maybridge4_001162 COc1ccc(cc1)C(=O)CN2CCCc3cc(C)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E19 compound treatment 0.265 0.0472 0.67 0.18 -0.0339 -0.57 0.0745 0.0843 1307254 Maybridge4_001163 COc1ccc(CN(Cc2cccn2C)S(=O)(=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E20 compound treatment 0.205 -0.0128 -0.18 0.202 -0.0119 -0.2 -0.2713 -0.999 1235221 Maybridge4_001164 Fc1cccc(Cl)c1CN2CCC(CC2)NS(=O)(=O)c3cccc4nonc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E21 compound treatment 0.172 -0.0458 -0.66 0.131 -0.0829 -1.39 -1.4477 -0.9409 3179795 Maybridge4_001165 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E22 compound treatment 0.21 -0.00781 -0.11 0.217 0.00306 0.05 -0.0427 -0.3469 1482186 Maybridge4_001166 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E23 mock treatment 0.189 -0.0288 -0.41 0.227 0.0131 0.22 -0.1364 -0.2922 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 E24 mock treatment 0.187 -0.0308 -0.44 0.227 0.0131 0.22 -0.1566 -0.3182 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F01 compound treatment 0.204 -0.0138 -0.2 0.226 0.0121 0.2 0.0035 0.0122 3063510 Maybridge4_001167 Fc1cccc(Cl)c1CN2CCC(CC2)NS(=O)(=O)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F02 compound treatment 0.22 0.00219 0.03 0.211 -0.00294 -0.05 -0.0127 -0.2181 1623040 Maybridge4_001168 CCN(CC)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F03 compound treatment 0.171 -0.0468 -0.67 0.137 -0.0769 -1.29 -1.3866 -0.9532 1283930 Maybridge4_001169 C1C(Cc2ccccc12)Nc3nc(ns3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F04 compound treatment 0.213 -0.00481 -0.07 0.212 -0.00194 -0.03 -0.0717 -0.9414 3179796 Maybridge4_001170 CC(C)(CC(=O)O)CC(=O)Nc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F05 compound treatment 0.246 0.0282 0.4 0.273 0.0591 0.99 0.9861 0.9214 3063512 Maybridge4_001171 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCN2CCNC2=O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F06 compound treatment 0.238 0.0202 0.29 0.272 0.0581 0.97 0.8933 0.8789 1430388 Maybridge4_001172 Cc1ccc(NC(=O)c2ccsc2)cc1NS(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F07 compound treatment 0.281 0.0632 0.9 0.275 0.0611 1.02 1.3638 0.998 1313330 Maybridge4_001173 Cc1oc(cc1C(=O)NCc2ccc3OCOc3c2)S(=O)(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F08 compound treatment 0.156 -0.0618 -0.88 0.152 -0.0619 -1.04 -1.3603 -0.9968 3063513 Maybridge4_001174 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3ccc(cc3Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F09 compound treatment 0.232 0.0142 0.2 0.235 0.0211 0.35 0.3935 0.9653 1684282 Maybridge4_001175 COC(=O)c1sccc1c2ccc(CN3CCC(CC3)c4ccccc4OC)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F10 compound treatment 0.27 0.0522 0.75 0.279 0.0651 1.09 1.3 0.9828 1364415 Maybridge4_001176 Cc1oc(cc1C(=O)NC2Cc3ccccc3C2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F11 compound treatment 0.271 0.0532 0.76 0.241 0.0271 0.45 0.8591 0.9696 3063529 Maybridge4_001177 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)c3ccc4OCCc4c3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F12 compound treatment 0.275 0.0572 0.82 0.209 -0.00494 -0.08 0.5198 0.6322 1341364 Maybridge4_001178 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)C4CCC4)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F13 compound treatment 0.289 0.0712 1.02 0.238 0.0241 0.4 1.0056 0.918 3063530 Maybridge4_001179 O=C(NCCN1CCN(Cc2ccccc2)CC1)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F14 compound treatment 0.274 0.0562 0.8 0.26 0.0461 0.77 1.115 0.9998 1693889 Maybridge4_001180 O=C(Nc1ccccc1)Nc2ccc(CC#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F15 compound treatment 0.276 0.0582 0.83 0.262 0.0481 0.81 1.1589 0.9999 3063531 Maybridge4_001181 Cc1nc(ccc1C(=O)NN2CCOCC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F16 compound treatment 0.283 0.0652 0.93 0.272 0.0581 0.97 1.3484 0.9998 1169808 Maybridge4_001182 O=C(Nc1cccc2ccccc12)N3CCN(CC3)c4ncccc4C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F17 compound treatment 0.32 0.102 1.46 0.329 0.115 1.93 2.3991 0.9906 3179797 Maybridge4_001183 Cc1onc(c1C(=O)N(C(=O)c2c(C)onc2c3ccccc3)c4ncc(C)nc4C)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F18 compound treatment 0.23 0.0122 0.17 0.245 0.0311 0.52 0.4919 0.8948 1265508 Maybridge4_001184 COc1ccc(OCC(O)CNC(=O)c2sccc2Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F19 compound treatment 0.281 0.0632 0.9 0.221 0.00706 0.12 0.7229 0.7931 3063532 Maybridge4_001185 COC(=O)c1cnc(nc1C(F)(F)F)N2CCCN(CC2)C(=O)c3cc(nn3C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F20 compound treatment 0.203 -0.0148 -0.21 0.235 0.0211 0.35 0.1002 0.243 3179798 Maybridge4_001186 CCOC(=O)N1CCC(CC1)NC(=O)Nc2cc(C)oc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F21 compound treatment 0.233 0.0152 0.22 0.248 0.0341 0.57 0.5579 0.9122 1597233 Maybridge4_001187 COc1cccc2n(C)nc(NC(=O)CSCC(=O)O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F22 compound treatment 0.237 0.0192 0.27 0.228 0.0141 0.24 0.361 0.9972 1439715 Maybridge4_001188 CCc1ccc(cc1)S(=O)(=O)NCC(O)COc2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F23 mock treatment 0.23 0.0122 0.17 0.23 0.0161 0.27 0.3139 0.9777 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 F24 mock treatment 0.216 -0.00181 -0.03 0.202 -0.0119 -0.2 -0.16 -0.792 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G01 compound treatment 0.207 -0.0108 -0.15 0.213 -9.38E-4 -0.02 -0.1205 -0.775 1075387 Maybridge4_001189 NC(=O)NC1CCCCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G02 compound treatment 0.199 -0.0188 -0.27 0.225 0.0111 0.19 -0.059 -0.1804 1679776 Maybridge4_001190 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NC2CCCCCCCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G03 compound treatment 0.239 0.0212 0.3 0.22 0.00606 0.1 0.2862 0.8954 3063533 Maybridge4_001191 COC(=O)c1cnc(nc1C(F)(F)F)n2ncc(C#N)c2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G04 compound treatment 0.269 0.0512 0.73 0.221 0.00706 0.12 0.6015 0.811 1394712 Maybridge4_001192 OCCN1CCN(CC1)C2=Cc3ccccc3C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G05 compound treatment 0.206 -0.0118 -0.17 0.232 0.0181 0.3 0.0949 0.2734 1644505 Maybridge4_001193 CC(C)(C)NC(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G06 compound treatment 0.265 0.0472 0.67 0.276 0.0621 1.04 1.2138 0.9779 3063534 Maybridge4_001194 OC(=O)COCC(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G07 compound treatment 0.238 0.0202 0.29 0.221 0.00706 0.12 0.288 0.9227 1201054 Maybridge4_001195 COc1ccccc1NC(=S)NC2CC3CCC2C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G08 compound treatment 0.056 -0.162 -2.31 0.057 -0.157 -2.63 -3.4992 -0.9979 1231183 Maybridge4_001196 CCOC(=O)c1cccc(c1)n2sc(=O)n(C3Cc4ccccc4C3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G09 compound treatment 0.234 0.0162 0.23 0.251 0.0371 0.62 0.6036 0.9094 1624776 Maybridge4_001197 Clc1ccc(s1)c2csc(n2)c3ccc4OCCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G10 compound treatment 0.236 0.0182 0.26 0.22 0.00606 0.1 0.2559 0.9161 1282547 Maybridge4_001198 COC(=O)c1ccc(n1C)S(=O)(=O)N(C2CCCCC2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G11 compound treatment 0.239 0.0212 0.3 0.192 -0.0219 -0.37 -0.0461 -0.0966 3063535 Maybridge4_001199 COC(=O)c1cc(oc1C)S(=O)(=O)Nc2cccc(c2)c3cnco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G12 compound treatment 0.055 -0.163 -2.33 0.056 -0.158 -2.65 -3.5211 -0.9979 3063536 Maybridge4_001200 FC(F)(F)c1ccccc1n2sc(=O)n(CC3CC3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G13 compound treatment 0.207 -0.0108 -0.15 0.233 0.0191 0.32 0.1169 0.3289 3178224 Maybridge4_001201 COc1ccc(Oc2ccc(cc2NS(=O)(=O)c3cccc4nonc34)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G14 compound treatment 0.2 -0.0178 -0.25 0.235 0.0211 0.35 0.0698 0.1602 3178225 Maybridge4_001202 FC(F)(F)c1cc(NC(=O)c2ccc(CN3C(=O)c4ccccc4C3=O)o2)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G15 compound treatment 0.249 0.0312 0.45 0.258 0.0441 0.74 0.8384 0.9707 3063537 Maybridge4_001203 OC(=O)c1sccc1S(=O)(=O)Nc2ccccc2N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G16 compound treatment 0.221 0.00319 0.05 0.212 -0.00194 -0.03 0.0092 0.1651 1305367 Maybridge4_001204 CC(C)(C)OC(=O)N1CCC(CNC(=O)Nc2ccccc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G17 compound treatment 0.204 -0.0138 -0.2 0.224 0.0101 0.17 -0.0203 -0.078 1532622 Maybridge4_001205 Clc1ccc(cc1Cl)n2c(SCC(=O)N3CCOCC3)nc4ccccc4c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G18 compound treatment 0.247 0.0292 0.42 0.281 0.0671 1.13 1.0911 0.9089 1304189 Maybridge4_001206 Fc1ccc(cc1)c2ccc(=O)n(CCC#N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G19 compound treatment 0.211 -0.00681 -0.1 0.251 0.0371 0.62 0.371 0.5892 1675293 Maybridge4_001207 Cn1nc(NC(=O)C2CCC2C(=O)O)c3c(F)cccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G20 compound treatment 0.231 0.0132 0.19 0.232 0.0181 0.3 0.3477 0.9739 1345399 Maybridge4_001208 COC(=O)c1sccc1NC(=O)c2cc(oc2C)S(=O)(=O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G21 compound treatment 0.24 0.0222 0.32 0.214 6.25E-5 0.0 0.2252 0.7094 1463889 Maybridge4_001209 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)c4ccc(C)c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G22 compound treatment 0.214 -0.00381 -0.05 0.21 -0.00394 -0.07 -0.0853 -0.9954 1398688 Maybridge4_001210 Cc1cc(NS(=O)(=O)c2ccc3OCCOc3c2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G23 mock treatment 0.173 -0.0448 -0.64 0.229 0.0151 0.25 -0.2745 -0.3984 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 G24 mock treatment 0.194 -0.0238 -0.34 0.218 0.00406 0.07 -0.1926 -0.5546 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H01 compound treatment 0.228 0.0102 0.15 0.204 -0.00994 -0.17 -0.0149 -0.0673 1708371 Maybridge4_001211 OC(=O)COCC(=O)NC1CCN(Cc2c(F)cccc2Cl)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H02 compound treatment 0.238 0.0202 0.29 0.171 -0.0429 -0.72 -0.3054 -0.3934 3063538 Maybridge4_001212 Clc1ccc2nc(Sc3ccccc3NS(=O)(=O)c4ccc(C#N)cc4)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H03 compound treatment 0.231 0.0132 0.19 0.194 -0.0199 -0.33 -0.1032 -0.2688 1419067 Maybridge4_001213 Cc1c(cnn1c2ccc(F)cc2)C(=O)N(Cc3ccccc3)Cc4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H04 compound treatment 0.227 0.00919 0.13 0.219 0.00506 0.08 0.153 0.9777 1711883 Maybridge4_001214 NS(=O)(=O)c1ccc(NC(=O)CC2(CC(=O)O)CCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H05 compound treatment 0.205 -0.0128 -0.18 0.25 0.0361 0.61 0.2984 0.4719 1352488 Maybridge4_001215 Clc1c(sc2ccccc12)C(=O)NCCN3CCNC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H06 compound treatment 0.262 0.0442 0.63 0.259 0.0451 0.76 0.9817 0.996 3178226 Maybridge4_001216 FC(F)(F)c1cc(no1)c2cc(cs2)S(=O)(=O)Nc3ccc4OCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H07 compound treatment 0.22 0.00219 0.03 0.248 0.0341 0.57 0.4264 0.7447 1151414 Maybridge4_001217 COc1ccccc1OCC(O)CNCc2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H08 compound treatment 0.24 0.0222 0.32 0.26 0.0461 0.77 0.7711 0.9227 1595899 Maybridge4_001218 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)c3ccccc3C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H09 compound treatment 0.253 0.0352 0.5 0.228 0.0141 0.24 0.5228 0.9404 3063539 Maybridge4_001219 CC(C)n1c(SCC(=O)Nc2ccccc2Cl)nc3cc(Cl)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H10 compound treatment 0.294 0.0762 1.09 0.204 -0.00994 -0.17 0.6526 0.592 3178227 Maybridge4_001220 Cc1nc(ccc1C(=O)Nc2ccccc2c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H11 compound treatment 0.187 -0.0308 -0.44 0.178 -0.0359 -0.6 -0.7382 -0.9881 1134518 Maybridge4_001221 CN(C(=O)c1ccc(Cl)cc1)c2ccc(Cl)cc2C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H12 compound treatment 0.271 0.0532 0.76 0.267 0.0531 0.89 1.1677 0.9969 1256492 Maybridge4_001222 CCCc1ccc(cc1)S(=O)(=O)Nc2ccc(C)c(NS(=O)(=O)C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H13 compound treatment 0.273 0.0552 0.79 0.276 0.0621 1.04 1.2947 0.9906 1621469 Maybridge4_001223 CCOC(=O)C1=C(NC(=O)NC1C)C(C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H14 compound treatment 0.308 0.0902 1.29 0.167 -0.0469 -0.79 0.3551 0.2349 1158832 Maybridge4_001224 CCc1ccnc(NC(=O)Nc2ccccc2C(C)(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H15 compound treatment 0.276 0.0582 0.83 0.264 0.0501 0.84 1.1827 1.0 3178228 Maybridge4_001225 O=S(=O)(NN1CCOCC1)c2cc(cs2)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H16 compound treatment 0.261 0.0432 0.62 0.283 0.0691 1.16 1.2564 0.9566 1405785 Maybridge4_001226 Clc1cncc(Cl)c1N2CCCN(CC2)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H17 compound treatment 0.293 0.0752 1.08 0.252 0.0381 0.64 1.2122 0.9691 3178229 Maybridge4_001227 Cn1c(Cc2ccsc2)nnc1Sc3nc4ccc(Cl)cc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H18 compound treatment 0.218 1.88E-4 0.0 0.24 0.0261 0.44 0.3112 0.7114 1596031 Maybridge4_001228 COc1ccc(OCC(O)CNC(=O)c2ccc(cc2)N(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H19 compound treatment 0.259 0.0412 0.59 0.274 0.0601 1.01 1.1294 0.9673 1496534 Maybridge4_001229 COC(=O)c1ccc(n1C)S(=O)(=O)NN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H20 compound treatment 0.229 0.0112 0.16 0.212 -0.00194 -0.03 0.0902 0.5521 1382593 Maybridge4_001230 CCOC(=O)N1CCC(CC1)NC(=O)Nc2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H21 compound treatment 0.236 0.0182 0.26 0.264 0.0501 0.84 0.7781 0.8846 1574673 Maybridge4_001231 COc1cccc2n(C)nc(NC(=O)c3nccnc3C(=O)O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H22 compound treatment 0.256 0.0382 0.55 0.242 0.0281 0.47 0.7193 0.9973 1461069 Maybridge4_001232 CCOc1ccccc1NC(=O)N2CCCN(CC2)c3ncccc3C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H23 mock treatment 0.222 0.00419 0.06 0.202 -0.0119 -0.2 -0.0993 -0.475 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 H24 mock treatment 0.2 -0.0178 -0.25 0.187 -0.0269 -0.45 -0.4999 -0.9632 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I01 compound treatment 0.19 -0.0278 -0.4 0.116 -0.0979 -1.64 -1.4436 -0.8536 1638533 Maybridge4_001233 CC(C)(C)c1ccc(cc1)c2cc(NS(=O)(=O)c3ccccc3)c(s2)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I02 compound treatment 0.221 0.00319 0.05 0.218 0.00406 0.07 0.0805 0.9809 3178230 Maybridge4_001234 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NCc2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I03 compound treatment 0.2 -0.0178 -0.25 0.225 0.0111 0.19 -0.0489 -0.155 1615822 Maybridge4_001235 CCC(CO)NC(=S)Nc1ccsc1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I04 compound treatment 0.258 0.0402 0.57 0.26 0.0461 0.77 0.9531 0.9894 1181672 Maybridge4_001236 COc1ccc(cc1)n2nnnc2c3c[nH]c4ccc(Cl)cc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I05 compound treatment 0.226 0.00819 0.12 0.203 -0.0109 -0.18 -0.047 -0.2158 3178231 Maybridge4_001237 OC(=O)/C=C\C(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I06 compound treatment 0.271 0.0532 0.76 0.209 -0.00494 -0.08 0.4794 0.6264 1121093 Maybridge4_001238 COC(=O)c1ccc(n1C)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I07 compound treatment 0.239 0.0212 0.3 0.259 0.0451 0.76 0.7491 0.9194 3178232 Maybridge4_001239 CCCN(CCC)C(=S)NC1CC2CC1C=C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I08 compound treatment 0.233 0.0152 0.22 0.242 0.0281 0.47 0.4867 0.9383 1340809 Maybridge4_001240 OC1CCN(CC1)C(=O)c2cccc(CN3CCN(CC3)c4nc(ns4)c5ccccc5)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I09 compound treatment 0.223 0.00519 0.07 0.256 0.0421 0.71 0.5517 0.7771 1278544 Maybridge4_001241 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3cccc4nonc34)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I10 compound treatment 0.289 0.0712 1.02 0.179 -0.0349 -0.59 0.3054 0.2599 1350689 Maybridge4_001242 COC(=O)c1ccc(n1C)S(=O)(=O)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I11 compound treatment 0.241 0.0232 0.33 0.228 0.0141 0.24 0.4014 0.9861 3178233 Maybridge4_001243 Cn1c(CSc2ccnc3cc(Cl)ccc23)nnc1SCC(=O)c4ccc(Cl)s4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I12 compound treatment 0.288 0.0702 1.0 0.291 0.0771 1.29 1.6245 0.9922 3063555 Maybridge4_001244 O/C(=C\Sc1nc2CCCCc2c(c1C#N)C(F)(F)F)/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I13 compound treatment 0.277 0.0592 0.85 0.22 0.00606 0.1 0.6706 0.7864 1516805 Maybridge4_001245 COC(=O)Cc1nc(NC(=O)C2CCC2C(=O)O)sc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I14 compound treatment 0.261 0.0432 0.62 0.261 0.0471 0.79 0.9954 0.9926 1616395 Maybridge4_001246 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc(F)cc2F)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I15 compound treatment 0.26 0.0422 0.6 0.247 0.0331 0.55 0.8191 0.9991 1670393 Maybridge4_001247 Cc1oc(cc1c2nc(no2)c3ccc(cc3)C(C)(C)C)S(=O)(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I16 compound treatment 0.185 -0.0328 -0.47 0.18 -0.0339 -0.57 -0.7346 -0.9954 1316867 Maybridge4_001248 CC(C)(C)c1ccc(cc1)c2nnc(SCc3cccc(c3)C(=O)N)n2c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I17 compound treatment 0.283 0.0652 0.93 0.246 0.0321 0.54 1.0398 0.9659 1620610 Maybridge4_001249 OC(CNCc1ccc2OCOc2c1)COc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I18 compound treatment 0.223 0.00519 0.07 0.204 -0.00994 -0.17 -0.0655 -0.3586 1465779 Maybridge4_001250 CC(=O)Nc1cccc(c1)n2nnc(SCC(=O)c3ccccc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I19 compound treatment 0.256 0.0382 0.55 0.255 0.0411 0.69 0.8736 0.9934 1598604 Maybridge4_001251 Cn1nc(NC(=O)CC(C)(C)CC(=O)O)c2c(F)cccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I20 compound treatment 0.245 0.0272 0.39 0.232 0.0181 0.3 0.4893 0.9924 1238878 Maybridge4_001252 Cc1oc(cc1C(=O)Nc2ccccc2)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I21 compound treatment 0.194 -0.0238 -0.34 0.236 0.0221 0.37 0.021 0.0417 1457140 Maybridge4_001253 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I22 compound treatment 0.178 -0.0398 -0.57 0.189 -0.0249 -0.42 -0.6986 -0.9885 1519073 Maybridge4_001254 O=S(=O)(NCC1CCN(CC1)S(=O)(=O)c2ccccc2)c3cccc4nonc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I23 mock treatment 0.2 -0.0178 -0.25 0.207 -0.00694 -0.12 -0.2625 -0.937 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 I24 mock treatment 0.191 -0.0268 -0.38 0.194 -0.0199 -0.33 -0.5078 -0.9977 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J01 compound treatment 0.215 -0.00281 -0.04 0.222 0.00806 0.14 0.0672 0.4763 1542762 Maybridge4_001255 OC(=O)c1nccnc1C(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J02 compound treatment 0.197 -0.0208 -0.3 0.198 -0.0159 -0.27 -0.3997 -0.9986 1359019 Maybridge4_001256 CCCc1cnc(nc1)N2CCN(CC2)C(=S)NC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J03 compound treatment 0.198 -0.0198 -0.28 0.185 -0.0289 -0.49 -0.5438 -0.9671 1448044 Maybridge4_001257 CC(C)n1c(SCC(=O)c2ccccc2)nc3cc(Cl)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J04 compound treatment 0.203 -0.0148 -0.21 0.234 0.0201 0.34 0.0883 0.2219 1537193 Maybridge4_001258 CCS(=O)(=O)c1ccc(O)c(NC(=O)CCCC(=O)O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J05 compound treatment 0.246 0.0282 0.4 0.228 0.0141 0.24 0.452 0.9675 1258625 Maybridge4_001259 Cc1oc(cc1C(=O)NCCN2CCNC2=O)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J06 compound treatment 0.243 0.0252 0.36 0.26 0.0461 0.77 0.8014 0.9396 1248986 Maybridge4_001260 Cc1ccc2n(CC(=O)c3ccccc3)c(=O)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J07 compound treatment 0.226 0.00819 0.12 0.244 0.0301 0.5 0.4396 0.8487 1612362 Maybridge4_001261 OC(=O)COCC(=O)Nc1ccc2COC(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J08 compound treatment 0.241 0.0232 0.33 0.248 0.0341 0.57 0.6388 0.9665 1623545 Maybridge4_001262 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)COCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J09 compound treatment 0.28 0.0622 0.89 0.246 0.0321 0.54 1.0095 0.971 3063556 Maybridge4_001263 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)NC3CCCCC3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J10 compound treatment 0.237 0.0192 0.27 0.288 0.0741 1.24 1.073 0.8429 3178332 Maybridge4_001264 O=C(CSc1nccc(n1)c2cccs2)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J11 compound treatment 0.244 0.0262 0.37 0.253 0.0391 0.66 0.7285 0.9647 3178333 Maybridge4_001265 Clc1cc(ccc1NC(=O)C2CCN(CC2)C(=O)OCc3ccccc3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J12 compound treatment 0.053 -0.165 -2.36 0.055 -0.159 -2.67 -3.5532 -0.9981 3063557 Maybridge4_001266 Cc1csc(NC(=O)c2ccccc2C(=O)O)c1c3nc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J13 compound treatment 0.25 0.0322 0.46 0.271 0.0571 0.96 1.0028 0.9437 3178334 Maybridge4_001267 Fc1cc(CNC(=O)c2ccc3nonc3c2)c4OCOCc4c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J14 compound treatment 0.261 0.0432 0.62 0.264 0.0501 0.84 1.031 0.9886 1272012 Maybridge4_001268 C1COc2cc(ccc2O1)c3cn4cccnc4n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J15 compound treatment 0.244 0.0262 0.37 0.307 0.0931 1.56 1.3693 0.8525 1207844 Maybridge4_001269 Cc1ccc(cc1)c2csc3ncnc(NCCN4CCNC4=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J16 compound treatment 0.278 0.0602 0.86 0.289 0.0751 1.26 1.4996 0.9828 3063558 Maybridge4_001270 OC(=O)COCC(=O)Nc1cccc(c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J17 compound treatment 0.255 0.0372 0.53 0.253 0.0391 0.66 0.8397 0.9946 1592295 Maybridge4_001271 Cn1nc(c(NC(=O)c2ccc(F)cc2)c1C(C)(C)C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J18 compound treatment 0.269 0.0512 0.73 0.257 0.0431 0.72 1.0288 1.0 1672779 Maybridge4_001272 O=C(Nc1ccccc1)Nc2ccc(C#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J19 compound treatment 0.278 0.0602 0.86 0.284 0.0701 1.18 1.4403 0.9882 1287020 Maybridge4_001273 Nc1nccc(n1)c2nn(ccc2=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J20 compound treatment 0.22 0.00219 0.03 0.272 0.0581 0.97 0.7112 0.7294 1290569 Maybridge4_001274 CCOC(=O)N1CCC(CC1)NC(=O)c2ccccc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J21 compound treatment 0.224 0.00619 0.09 0.282 0.0681 1.14 0.8704 0.7596 1226002 Maybridge4_001275 Cc1nn(C)cc1NC(=O)Nc2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J22 compound treatment 0.277 0.0592 0.85 0.224 0.0101 0.17 0.7181 0.8318 3178335 Maybridge4_001276 O=C(Nc1ccccc1)N(CCC#N)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J23 mock treatment 0.204 -0.0138 -0.2 0.209 -0.00494 -0.08 -0.1983 -0.9256 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 J24 mock treatment 0.2 -0.0178 -0.25 0.202 -0.0119 -0.2 -0.3218 -0.9929 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K01 compound treatment 0.24 0.0222 0.32 0.244 0.0301 0.5 0.5812 0.975 1539150 Maybridge4_001277 CC(C)(C)c1cc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K02 compound treatment 0.222 0.00419 0.06 0.222 0.00806 0.14 0.138 0.9328 1563937 Maybridge4_001278 COC(=O)c1c(C)oc(C)c1S(=O)(=O)Nc2ccc(cc2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K03 compound treatment 0.263 0.0452 0.65 0.232 0.0181 0.3 0.6714 0.9405 3063559 Maybridge4_001279 CCC1CSc2nc3ccsc3c(=O)n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K04 compound treatment 0.237 0.0192 0.27 0.233 0.0191 0.32 0.4203 0.9971 3178336 Maybridge4_001280 FC(F)(F)c1cccc(c1)N2CCN(CC2)C3=Cc4ccccc4CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K05 compound treatment 0.064 -0.154 -2.2 0.064 -0.15 -2.52 -3.3352 -0.9978 3063560 Maybridge4_001281 FC(F)(F)c1ccnc(S)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K06 compound treatment 0.235 0.0172 0.25 0.218 0.00406 0.07 0.2221 0.8704 3178337 Maybridge4_001282 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccc(cc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K07 compound treatment 0.217 -8.12E-4 -0.01 0.16 -0.0539 -0.91 -0.6484 -0.7161 1176274 Maybridge4_001283 CC1CC(CC(C)(C)C1)NC(=S)NC2CC3CC2C=C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K08 compound treatment 0.262 0.0442 0.63 0.252 0.0381 0.64 0.8987 1.0 1427567 Maybridge4_001284 Cc1ccc(C)n1c2ccc(cc2)C3(O)CCSc4ccccc43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K09 compound treatment 0.25 0.0322 0.46 0.302 0.0881 1.48 1.3707 0.8854 1358302 Maybridge4_001285 CC(C)(C)OC(=O)N1CCC(CC1)c2nc(cs2)c3ccc(Cl)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K10 compound treatment 0.264 0.0462 0.66 0.26 0.0461 0.77 1.0138 0.9969 1583408 Maybridge4_001286 COc1ccccc1CCNS(=O)(=O)c2ccc(C(=O)O)n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K11 compound treatment 0.195 -0.0228 -0.33 0.264 0.0501 0.84 0.3634 0.4032 3178338 Maybridge4_001287 OC1(CCN(CC1)C(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K12 compound treatment 0.235 0.0172 0.25 0.216 0.00206 0.03 0.1983 0.7988 3063561 Maybridge4_001288 OC1(NC(=O)c2cnn(c2C(F)(F)F)c3ccccc3)C(=O)c4ccccc4C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K13 compound treatment 0.217 -8.12E-4 -0.01 0.273 0.0591 0.99 0.6927 0.6988 3178339 Maybridge4_001289 COc1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1OC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K14 compound treatment 0.241 0.0232 0.33 0.226 0.0121 0.2 0.3777 0.972 1513815 Maybridge4_001290 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc3cccnc23)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K15 compound treatment 0.053 -0.165 -2.36 0.056 -0.158 -2.65 -3.5414 -0.9983 1269818 Maybridge4_001291 Cc1cc(NS(=O)(=O)c2ccc(NCN3C(=O)c4ccccc4C3=O)cc2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K16 compound treatment 0.237 0.0192 0.27 0.252 0.0381 0.64 0.6458 0.9288 3178340 Maybridge4_001292 CC(C)NC(=O)CSc1nnc(c2ccc(cc2)C(C)(C)C)n1c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K17 compound treatment 0.244 0.0262 0.37 0.205 -0.00894 -0.15 0.1588 0.3935 1222771 Maybridge4_001293 NC(=O)C1CCN(CC(O)COc2ccc(F)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K18 compound treatment 0.237 0.0192 0.27 0.214 6.25E-5 0.0 0.1948 0.7098 1223041 Maybridge4_001294 CC(=O)Nc1cccc(c1)n2nnc(SCc3cc(Cl)cc4COCOc34)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K19 compound treatment 0.231 0.0132 0.19 0.24 0.0261 0.44 0.4427 0.9293 1546521 Maybridge4_001295 COc1ccc2[nH]c(cc2c1)C(=O)N3CCC(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K20 compound treatment 0.21 -0.00781 -0.11 0.205 -0.00894 -0.15 -0.1851 -0.9895 1729108 Maybridge4_001296 Cc1oc(cc1c2nc(no2)c3ccc(F)cc3)S(=O)(=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K21 compound treatment 0.253 0.0352 0.5 0.237 0.0231 0.39 0.6296 0.9916 3178447 Maybridge4_001297 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K22 compound treatment 0.25 0.0322 0.46 0.226 0.0121 0.2 0.4687 0.9319 1411945 Maybridge4_001298 Cc1ccc(Oc2ncccc2NS(=O)(=O)c3ccc(s3)c4ccccn4)c5CCCc51 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K23 mock treatment 0.243 0.0252 0.36 0.182 -0.0319 -0.54 -0.1243 -0.1924 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 K24 mock treatment 0.231 0.0132 0.19 0.22 0.00606 0.1 0.2053 0.958 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L01 compound treatment 0.24 0.0222 0.32 0.186 -0.0279 -0.47 -0.1072 -0.1893 3178448 Maybridge4_001299 COCc1cc(O)nc(SCC(=O)c2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L02 compound treatment 0.223 0.00519 0.07 0.203 -0.0109 -0.18 -0.0773 -0.3906 3063562 Maybridge4_001300 Fc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)c3nccc(n3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L03 compound treatment 0.236 0.0182 0.26 0.228 0.0141 0.24 0.3508 0.9988 3178449 Maybridge4_001301 Nc1nc(SCC(=O)c2cc(no2)c3ccccc3)ncc1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L04 compound treatment 0.249 0.0312 0.45 0.205 -0.00894 -0.15 0.2094 0.4449 1497829 Maybridge4_001302 CCCNC(=O)Nc1cc(ccc1O)S(=O)(=O)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L05 compound treatment 0.234 0.0162 0.23 0.201 -0.0129 -0.22 0.0102 0.0321 1614464 Maybridge4_001303 OC(CN(CCN1CCNC1=O)CC(O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L06 compound treatment 0.213 -0.00481 -0.07 0.191 -0.0229 -0.38 -0.3209 -0.8205 1416766 Maybridge4_001304 Clc1ccc2scc(CNS(=O)(=O)c3cc(cs3)S(=O)(=O)c4ccccc4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L07 compound treatment 0.222 0.00419 0.06 0.195 -0.0189 -0.32 -0.1824 -0.5639 3063563 Maybridge4_001305 O=C(Nc1ccc2COC(=O)c2c1)c3cc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L08 compound treatment 0.273 0.0552 0.79 0.226 0.0121 0.2 0.7013 0.8606 3178450 Maybridge4_001306 Cc1cc(NC(=O)NCCNc2ncccc2C(F)(F)F)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L09 compound treatment 0.222 0.00419 0.06 0.252 0.0381 0.64 0.4941 0.77 3178451 Maybridge4_001307 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)c3cccs3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L10 compound treatment 0.221 0.00319 0.05 0.244 0.0301 0.5 0.389 0.7679 3063564 Maybridge4_001308 O=C(CSc1nccc(n1)c2cccs2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L11 compound treatment 0.232 0.0142 0.2 0.202 -0.0119 -0.2 0.0018 0.0064 1340769 Maybridge4_001309 Cc1c(csc1C(=O)NC2CCN(Cc3ccccc3)CC2)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L12 compound treatment 0.243 0.0252 0.36 0.215 0.00106 0.02 0.2674 0.7412 1452839 Maybridge4_001310 Clc1cccc(Oc2ccccc2)c1CNC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L13 compound treatment 0.243 0.0252 0.36 0.26 0.0461 0.77 0.8014 0.9396 1545947 Maybridge4_001311 Cc1ccc(cc1)S(=O)(=O)NC(=O)OCCn2ncc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L14 compound treatment 0.283 0.0652 0.93 0.27 0.0561 0.94 1.3247 1.0 1335669 Maybridge4_001312 O=C(Nc1ccccc1)Nc2ccccc2C(=O)NCC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L15 compound treatment 0.203 -0.0148 -0.21 0.251 0.0371 0.62 0.29 0.4414 1301958 Maybridge4_001313 O=C1NCCN1CCNc2cccc(C#N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L16 compound treatment 0.241 0.0232 0.33 0.201 -0.0129 -0.22 0.081 0.2043 1237826 Maybridge4_001314 OC(=O)c1cccc(NC(=O)c2nccnc2C(=O)O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L17 compound treatment 0.257 0.0392 0.56 0.241 0.0271 0.45 0.7175 0.9946 1167798 Maybridge4_001315 CCOC(=O)C1CCN(CC1)c2ccccc2CN3CCCc4cc(C)ccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L18 compound treatment 0.262 0.0442 0.63 0.221 0.00706 0.12 0.5307 0.8253 1532681 Maybridge4_001316 O=C(NCC1CC1)c2ccccc2NS(=O)(=O)c3cccc4nonc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L19 compound treatment 0.218 1.88E-4 0.0 0.235 0.0211 0.35 0.2519 0.7125 3178452 Maybridge4_001317 COc1ccc(OCCNC(=O)c2nccnc2C(=O)O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L20 compound treatment 0.258 0.0402 0.57 0.275 0.0611 1.02 1.1312 0.9626 3063588 Maybridge4_001318 OC(=O)COCC(=O)Nc1ccc(cc1)n2ccc(n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L21 compound treatment 0.117 -0.101 -1.44 0.071 -0.143 -2.4 -2.716 -0.9703 1125657 Maybridge4_001319 NC(=O)C1CCN(CC1)C(=O)Nc2cc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L22 compound treatment 0.263 0.0452 0.65 0.294 0.0801 1.34 1.4072 0.9437 3063589 Maybridge4_001320 Cc1ccc(cc1)S(=O)(=O)CCSCc2csc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L23 mock treatment 0.264 0.0462 0.66 0.248 0.0341 0.57 0.8714 0.9974 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 L24 mock treatment 0.24 0.0222 0.32 0.202 -0.0119 -0.2 0.0827 0.2204 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M01 compound treatment 0.297 0.0792 1.13 0.254 0.0401 0.67 1.2764 0.969 1132483 Maybridge4_001321 N(c1ccccc1)c2ncnc3cc(sc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M02 compound treatment 0.137 -0.0808 -1.16 0.124 -0.0899 -1.51 -1.8847 -0.9913 1732345 Maybridge4_001322 OC(=O)CSCC(=O)N1CCN(CC1)S(=O)(=O)c2cc(Cl)cc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M03 compound treatment 0.252 0.0342 0.49 0.238 0.0241 0.4 0.6314 0.9955 1627433 Maybridge4_001323 NCCNC(=O)Cc1ccc(O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M04 compound treatment 0.175 -0.0428 -0.61 0.204 -0.00994 -0.17 -0.551 -0.8681 1237825 Maybridge4_001324 O=C(Nc1nc2ccccc2c(=O)s1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M05 compound treatment 0.239 0.0212 0.3 0.174 -0.0399 -0.67 -0.2597 -0.353 1700739 Maybridge4_001325 OC(CSc1cccs1)CSc2ccccc2NC(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M06 compound treatment 0.257 0.0392 0.56 0.253 0.0391 0.66 0.8599 0.997 1271443 Maybridge4_001326 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccsc2C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M07 compound treatment 0.254 0.0362 0.52 0.21 -0.00394 -0.07 0.3193 0.6119 3063590 Maybridge4_001327 S=C(NC(Cc1ccccc1)c2ccccc2)NC3CC4CC3C=C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M08 compound treatment 0.232 0.0142 0.2 0.215 0.00106 0.02 0.1561 0.7663 1434508 Maybridge4_001328 Fc1ccc2[nH]cc(CCCN3CCN(CC3)c4nc5cc(Cl)ccc5s4)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M09 compound treatment 0.154 -0.0638 -0.91 0.113 -0.101 -1.69 -1.8433 -0.9579 1293074 Maybridge4_001329 COC(=O)c1cc(oc1C)S(=O)(=O)Nc2nn(C)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M10 compound treatment 0.225 0.00719 0.1 0.204 -0.00994 -0.17 -0.0452 -0.2309 1681613 Maybridge4_001330 O=C(NCc1ccc2OCOc2c1)c3cc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M11 compound treatment 0.221 0.00319 0.05 0.169 -0.0449 -0.75 -0.5011 -0.6632 1565655 Maybridge4_001331 CC(C)(C)c1ccc(cc1)S(=O)(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M12 compound treatment 0.242 0.0242 0.35 0.206 -0.00794 -0.13 0.1504 0.4058 1050571 Maybridge4_001332 OC(=O)CCc1cccnc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M13 compound treatment 0.29 0.0722 1.03 0.204 -0.00994 -0.17 0.6122 0.5853 1126449 Maybridge4_001333 COc1ccc(NC(=O)C2CCCCC2)cc1OC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M14 compound treatment 0.258 0.0402 0.57 0.237 0.0231 0.39 0.6802 0.9815 1537113 Maybridge4_001334 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2ccc3OCCOc3c2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M15 compound treatment 0.271 0.0532 0.76 0.275 0.0611 1.02 1.2626 0.9892 1458162 Maybridge4_001335 CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)N3C(=O)CSCC3=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M16 compound treatment 0.098 -0.12 -1.71 0.118 -0.0959 -1.61 -2.3504 -0.9995 1342126 Maybridge4_001336 NC(=O)NC(=O)Cc1nc2ccccc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M17 compound treatment 0.272 0.0542 0.78 0.25 0.0361 0.61 0.9761 0.9925 1668027 Maybridge4_001337 OC(CNC1Cc2ccccc2C1)COc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M18 compound treatment 0.217 -8.12E-4 -0.01 0.234 0.0201 0.34 0.2299 0.6823 3063591 Maybridge4_001338 OC(=O)CSc1nc2cccnc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M19 compound treatment 0.196 -0.0218 -0.31 0.258 0.0441 0.74 0.3023 0.3766 1290479 Maybridge4_001339 NC(=O)C1CCN(CC(O)COc2ccc3OCOc3c2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M20 compound treatment 0.221 0.00319 0.05 0.245 0.0311 0.52 0.4009 0.766 1132021 Maybridge4_001340 COC(=O)c1scc(C)c1NS(=O)(=O)c2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M21 compound treatment 0.238 0.0202 0.29 0.216 0.00206 0.03 0.2287 0.7862 1157417 Maybridge4_001341 COc1ccc(cc1OC)S(=O)(=O)n2nc(n3c(C)ccc3C)c4c(F)cccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M22 compound treatment 0.225 0.00719 0.1 0.233 0.0191 0.32 0.2989 0.8895 1722963 Maybridge4_001342 Cc1nc(cn1C)S(=O)(=O)N2CCC(CC2)NC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M23 mock treatment 0.229 0.0112 0.16 0.238 0.0241 0.4 0.3987 0.9179 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 M24 mock treatment 0.226 0.00819 0.12 0.238 0.0241 0.4 0.3684 0.8761 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N01 compound treatment 0.25 0.0322 0.46 0.251 0.0371 0.62 0.7654 0.989 1329289 Maybridge4_001343 OC(=O)c1ccccc1C(=O)NCCN2CCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N02 compound treatment 0.238 0.0202 0.29 0.23 0.0161 0.27 0.3948 0.9994 3178453 Maybridge4_001344 FC(F)(F)c1ccnc(n1)N2CCCN(CC2)S(=O)(=O)c3cccc4nonc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N03 compound treatment 0.211 -0.00681 -0.1 0.21 -0.00394 -0.07 -0.1156 -0.9821 1118431 Maybridge4_001345 CCOC(=O)c1cc(NC(=O)CC(C)(C)CC(=O)O)ccc1N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N04 compound treatment 0.219 0.00119 0.02 0.24 0.0261 0.44 0.3213 0.734 1615128 Maybridge4_001346 CCS(=O)(=O)c1ccc(O)c(NC(=O)Nc2ccccc2OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N05 compound treatment 0.256 0.0382 0.55 0.199 -0.0149 -0.25 0.209 0.3477 3178454 Maybridge4_001347 Cc1nc(cn1C)S(=O)(=O)NCCNc2ccc(nn2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N06 compound treatment 0.207 -0.0108 -0.15 0.213 -9.38E-4 -0.02 -0.1205 -0.775 3063592 Maybridge4_001348 FC(F)(F)c1ccc(cc1)S(=O)(=O)Nc2ccc3COC(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N07 compound treatment 0.216 -0.00181 -0.03 0.214 6.25E-5 0.0 -0.0176 -0.6779 1059288 Maybridge4_001349 O=C1NC(Nc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N08 compound treatment 0.235 0.0172 0.25 0.232 0.0181 0.3 0.3882 0.9946 3063593 Maybridge4_001350 Cc1cc(NC(=O)Nc2ccccc2)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N09 compound treatment 0.25 0.0322 0.46 0.231 0.0171 0.29 0.5281 0.9739 3178455 Maybridge4_001351 COc1cccc(c1)C(=O)NCCN2CCN(CC2)c3nccc(n3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N10 compound treatment 0.233 0.0152 0.22 0.262 0.0481 0.81 0.724 0.8667 1126742 Maybridge4_001352 Cc1cc(NC(=O)CCCC(=O)O)n(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N11 compound treatment 0.243 0.0252 0.36 0.209 -0.00494 -0.08 0.1962 0.5306 1374549 Maybridge4_001353 COc1ccccc1C2CCN(CC2)C(=O)c3scc(c3C)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N12 compound treatment 0.151 -0.0668 -0.96 0.142 -0.0719 -1.21 -1.5295 -0.9933 1540730 Maybridge4_001354 Cc1oc(cc1C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N13 compound treatment 0.219 0.00119 0.02 0.24 0.0261 0.44 0.3213 0.734 1417640 Maybridge4_001355 O=C(Nc1cccc2ccccc12)OCCn3ncc4ccccc4c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N14 compound treatment 0.233 0.0152 0.22 0.206 -0.00794 -0.13 0.0594 0.2331 1318344 Maybridge4_001356 COC(=O)c1sccc1S(=O)(=O)Nc2ccc3OCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N15 compound treatment 0.231 0.0132 0.19 0.278 0.0641 1.08 0.8937 0.8187 3178549 Maybridge4_001357 FC(F)(F)Oc1ccc(NC(=S)NCCN2CCNC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N16 compound treatment 0.204 -0.0138 -0.2 0.262 0.0481 0.81 0.4307 0.5186 1460315 Maybridge4_001358 COc1ccc(OCC(O)CNC(=O)c2cc(nn2C)C(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N17 compound treatment 0.215 -0.00281 -0.04 0.221 0.00706 0.12 0.0554 0.4423 1196797 Maybridge4_001359 CCCc1c(cnn1c2ccccc2)C(=O)NC3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N18 compound treatment 0.209 -0.00881 -0.13 0.208 -0.00594 -0.1 -0.1596 -0.9932 3178550 Maybridge4_001360 COc1cc(OCc2ccccc2)ccc1CN3CCN(CC3)c4ccc(cn4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N19 compound treatment 0.198 -0.0198 -0.28 0.136 -0.0779 -1.31 -1.1254 -0.8408 1300856 Maybridge4_001361 O=C(NC1Cc2ccccc2C1)Nc3cc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N20 compound treatment 0.218 1.88E-4 0.0 0.214 6.25E-5 0.0 0.0026 0.9161 1617412 Maybridge4_001362 OC(=O)CC(CC(=O)N1CCN(CC1)C(=O)c2ccco2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N21 compound treatment 0.228 0.0102 0.15 0.235 0.0211 0.35 0.353 0.9232 1534103 Maybridge4_001363 OC(COc1ccc(cc1)c2csnn2)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N22 compound treatment 0.251 0.0332 0.47 0.272 0.0581 0.97 1.0248 0.9454 3063594 Maybridge4_001364 Clc1ccc(c(Cl)c1)S(=O)(=O)CCSCc2csc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N23 mock treatment 0.257 0.0392 0.56 0.224 0.0101 0.17 0.5158 0.881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 N24 mock treatment 0.244 0.0262 0.37 0.236 0.0221 0.37 0.5267 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O01 compound treatment 0.244 0.0262 0.37 0.25 0.0361 0.61 0.6929 0.9734 1379542 Maybridge4_001365 CC(C)(C)c1cc2ncnc(N3CCCCC3)c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O02 compound treatment 0.219 0.00119 0.02 0.217 0.00306 0.05 0.0484 0.8933 1268570 Maybridge4_001366 Cc1cc(OCC(=O)N(C2CCCCC2)c3ccccc3)c4ccccc4n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O03 compound treatment 0.233 0.0152 0.22 0.266 0.0521 0.87 0.7715 0.8568 3063595 Maybridge4_001367 FC(F)(F)c1ccn(n1)S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O04 compound treatment 0.21 -0.00781 -0.11 0.261 0.0471 0.79 0.4795 0.6011 1471781 Maybridge4_001368 Cc1csc2c(=O)sc(NC(=O)c3cccs3)nc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O05 compound treatment 0.237 0.0192 0.27 0.217 0.00306 0.05 0.2304 0.8252 3178551 Maybridge4_001369 COC(=O)c1cn(Cc2ccc(Cl)cc2)cc(F)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O06 compound treatment 0.259 0.0412 0.59 0.225 0.0111 0.19 0.5479 0.887 1122209 Maybridge4_001370 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCCN(Cc3ccccc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O07 compound treatment 0.22 0.00219 0.03 0.228 0.0141 0.24 0.189 0.7939 1177633 Maybridge4_001371 CC(C)(CCO)NC(=S)NC1CC2CC1C=C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O08 compound treatment 0.211 -0.00681 -0.1 0.24 0.0261 0.44 0.2404 0.5364 1162225 Maybridge4_001372 CCNC(=O)c1c(C)onc1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O09 compound treatment 0.218 1.88E-4 0.0 0.206 -0.00794 -0.13 -0.0923 -0.6927 3063596 Maybridge4_001373 Cc1csc2c(NCCCN3CCOCC3)ncnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O10 compound treatment 0.232 0.0142 0.2 0.23 0.0161 0.27 0.3341 0.9902 3178552 Maybridge4_001374 COc1ccc(cc1)c2cc(C(=O)Nc3ccc(F)cc3)c(o2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O11 compound treatment 0.229 0.0112 0.16 0.212 -0.00194 -0.03 0.0902 0.5521 3063597 Maybridge4_001375 Fc1ccc(cc1)S(=O)(=O)N2CCN=C(C=C2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O12 compound treatment 0.198 -0.0198 -0.28 0.226 0.0121 0.2 -0.0572 -0.1643 1566889 Maybridge4_001376 O=C(Nc1ccc2OCCOc2c1)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O13 compound treatment 0.192 -0.0258 -0.37 0.224 0.0101 0.17 -0.1417 -0.3489 3178553 Maybridge4_001377 CC(=O)Nc1c(c(nn1C)C(F)(F)F)c2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O14 compound treatment 0.211 -0.00681 -0.1 0.245 0.0311 0.52 0.2997 0.5652 1314147 Maybridge4_001378 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cc(Cl)sc2Cl)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O15 compound treatment 0.2 -0.0178 -0.25 0.226 0.0121 0.2 -0.037 -0.1137 1617882 Maybridge4_001379 OC(=O)CC1(CC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)CCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O16 compound treatment 0.133 -0.0848 -1.21 0.072 -0.142 -2.38 -2.5423 -0.951 3063620 Maybridge4_001380 Cc1nc(nc(SCC(=O)c2ccc(F)cc2)c1Cl)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O17 compound treatment 0.118 -0.0998 -1.43 0.151 -0.0629 -1.06 -1.7565 -0.989 1499688 Maybridge4_001381 NC(=O)C1CCN(Cn2nnc3ccccc23)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O18 compound treatment 0.24 0.0222 0.32 0.185 -0.0289 -0.49 -0.119 -0.2051 1432924 Maybridge4_001382 COc1ccc(CCNC(=O)c2cc3ccccc3s2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O19 compound treatment 0.227 0.00919 0.13 0.211 -0.00294 -0.05 0.0581 0.4137 1075902 Maybridge4_001383 COc1ccccc1NC(=O)Nc2ccccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O20 compound treatment 0.216 -0.00181 -0.03 0.242 0.0281 0.47 0.3147 0.6672 3063621 Maybridge4_001384 Fc1ccc(cc1)S(=O)(=O)CCN2CCN=C(C=C2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O21 compound treatment 0.218 1.88E-4 0.0 0.217 0.00306 0.05 0.0382 0.743 1600262 Maybridge4_001385 O=C(CC1(CC2CC3CC(C2)C1)C3)NCc4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O22 compound treatment 0.211 -0.00681 -0.1 0.199 -0.0149 -0.25 -0.2462 -0.9152 1226207 Maybridge4_001386 OC(=O)CCn1nc(ccc1=O)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O23 mock treatment 0.216 -0.00181 -0.03 0.188 -0.0259 -0.44 -0.3262 -0.7479 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 O24 mock treatment 0.207 -0.0108 -0.15 0.244 0.0301 0.5 0.2474 0.4688 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P01 compound treatment 0.231 0.0132 0.19 0.222 0.00806 0.14 0.2291 0.9867 1550189 Maybridge4_001387 Cc1ccc(cc1)C(=O)NCCN2CCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P02 compound treatment 0.239 0.0212 0.3 0.235 0.0211 0.35 0.4643 0.9971 3178554 Maybridge4_001388 Cc1ccsc1CNC(=O)Nc2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P03 compound treatment 0.248 0.0302 0.43 0.24 0.0261 0.44 0.6146 1.0 3063622 Maybridge4_001389 CCOC(=O)C(C#N)C1C(=C(N)Oc2c(C)cc(Cl)cc12)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P04 compound treatment 0.225 0.00719 0.1 0.237 0.0231 0.39 0.3464 0.8649 1160881 Maybridge4_001390 COC(=O)c1sccc1c2ccc(CN3CCCc4cc(OC)ccc34)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P05 compound treatment 0.237 0.0192 0.27 0.231 0.0171 0.29 0.3966 0.9998 1537339 Maybridge4_001391 COC(=O)c1sccc1S(=O)(=O)NC2CCS(=O)(=O)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P06 compound treatment 0.216 -0.00181 -0.03 0.223 0.00906 0.15 0.0892 0.5782 3178555 Maybridge4_001392 O=C1OCc2ccc(NS(=O)(=O)c3ccccc3C#N)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P07 compound treatment 0.136 -0.0818 -1.17 0.15 -0.0639 -1.07 -1.5863 -0.9991 1343805 Maybridge4_001393 O=C(NC1CCN(Cc2ccccc2)CC1)Nc3cc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P08 compound treatment 0.242 0.0242 0.35 0.222 0.00806 0.14 0.3403 0.9161 3063623 Maybridge4_001394 Cc1cc(NC(=O)NCc2ccccc2)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P09 compound treatment 0.255 0.0372 0.53 0.24 0.0261 0.44 0.6854 0.9953 3178556 Maybridge4_001395 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)c3ccc(Cl)cc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P10 compound treatment 0.244 0.0262 0.37 0.249 0.0351 0.59 0.681 0.9762 1315475 Maybridge4_001396 Cc1oc(cc1C(=O)NCc2csc3ccc(Cl)cc23)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P11 compound treatment 0.232 0.0142 0.2 0.243 0.0291 0.49 0.4884 0.9245 1707754 Maybridge4_001397 Cc1c(csc1C(=O)N2CCCc3cc(C)ccc23)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P12 compound treatment 0.181 -0.0368 -0.53 0.225 0.0111 0.19 -0.241 -0.4317 1437749 Maybridge4_001398 CC(C)c1ccc(NC(=O)c2cc(oc2C)C(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P13 compound treatment 0.203 -0.0148 -0.21 0.232 0.0181 0.3 0.0646 0.1745 3178557 Maybridge4_001399 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)c3cccs3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P14 compound treatment 0.247 0.0292 0.42 0.237 0.0231 0.39 0.5689 0.9993 1200741 Maybridge4_001400 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2ncccc2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P15 compound treatment 0.232 0.0142 0.2 0.219 0.00506 0.08 0.2036 0.9253 1650074 Maybridge4_001401 CCOC(=O)c1ccc(NC(=S)NCCN2CCNC2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P16 compound treatment 0.247 0.0292 0.42 0.231 0.0171 0.29 0.4977 0.9831 1225431 Maybridge4_001402 COc1ccc(OCC(O)CNC(=O)c2cccnc2Oc3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P17 compound treatment 0.245 0.0272 0.39 0.232 0.0181 0.3 0.4893 0.9924 1670405 Maybridge4_001403 CCCc1c(cnn1c2ccccc2)C(=O)NC3Cc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P18 compound treatment 0.243 0.0252 0.36 0.234 0.0201 0.34 0.4929 0.9994 1600703 Maybridge4_001404 COc1cc(OCc2ccccc2)ccc1CN3CCC(CC3)C(=O)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P19 compound treatment 0.253 0.0352 0.5 0.212 -0.00194 -0.03 0.3329 0.66 1497768 Maybridge4_001405 Fc1ccc(NC(=O)Nc2cc3ccccc3s2)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P20 compound treatment 0.292 0.0742 1.06 0.265 0.0511 0.86 1.3564 0.9944 1490941 Maybridge4_001406 Cc1nnsc1C(=O)NCc2c(Cl)cccc2Sc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P21 compound treatment 0.246 0.0282 0.4 0.244 0.0301 0.5 0.6419 0.9938 1271550 Maybridge4_001407 OC(CNCc1ccc2OCOc2c1)COc3ccc(cc3)c4csnn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P22 compound treatment 0.243 0.0252 0.36 0.224 0.0101 0.17 0.3742 0.9404 3063624 Maybridge4_001408 CC1(C)CCc2cc(CN3CCN(CC3)c4ncc(cc4Cl)C(F)(F)F)ccc2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P23 mock treatment 0.24 0.0222 0.32 0.241 0.0271 0.45 0.5456 0.9846 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2052 P24 mock treatment 0.213 -0.00481 -0.07 0.227 0.0131 0.22 0.1064 0.4628 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A01 compound treatment 0.214 -0.00122 -0.02 0.242 0.0253 0.43 0.2885 0.6776 1291502 Maybridge4_001409 Fc1ccc(cc1)c2n[nH]cc2CN3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A02 compound treatment 0.209 -0.00622 -0.09 0.22 0.00334 0.06 -0.0232 -0.2207 1286225 Maybridge4_001410 O=C(NC1CCN(CC1)C(=O)OCc2ccccc2)Nc3ccccc3N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A03 compound treatment 0.225 0.00978 0.14 0.256 0.0393 0.66 0.5659 0.8383 1251898 Maybridge4_001411 Cc1cc(C)c(SCC(=O)NCc2ccc3OCOc3c2)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A04 compound treatment 0.26 0.0448 0.64 0.224 0.00734 0.12 0.5401 0.828 1262294 Maybridge4_001412 CCCCN1Cc2c([nH]c3cc(nn3c2=O)C(C)(C)C)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A05 compound treatment 0.249 0.0338 0.48 0.204 -0.0127 -0.21 0.1915 0.3627 1594634 Maybridge4_001413 OC(=O)CCCC(=O)NC1CCCc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A06 compound treatment 0.247 0.0318 0.45 0.258 0.0413 0.69 0.8121 0.979 3178643 Maybridge4_001414 COc1cc2CCN(Cc3sc4ccccc4c3C)C(C)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A07 compound treatment 0.207 -0.00822 -0.12 0.212 -0.00466 -0.08 -0.1384 -0.9803 1319283 Maybridge4_001415 OC(CNC(=O)Nc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A08 compound treatment 0.22 0.00478 0.07 0.196 -0.0207 -0.35 -0.1968 -0.5569 1715585 Maybridge4_001416 Cc1cccc(NC(=O)c2ccco2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A09 compound treatment 0.231 0.0158 0.23 0.249 0.0323 0.54 0.5435 0.9244 1554836 Maybridge4_001417 CCCc1cnc(nc1)N2CCN(CC2)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A10 compound treatment 0.216 7.81E-4 0.01 0.276 0.0593 1.0 0.7122 0.715 3178644 Maybridge4_001418 O=S(=O)(Nc1ccccc1N2CCOCC2)c3ccc(s3)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A11 compound treatment 0.238 0.0228 0.33 0.274 0.0573 0.96 0.911 0.8965 3178645 Maybridge4_001419 Cc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A12 compound treatment 0.231 0.0158 0.23 0.227 0.0103 0.17 0.2824 0.9916 3063626 Maybridge4_001420 Oc1nnc(S)n1C2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A13 compound treatment 0.239 0.0238 0.34 0.266 0.0493 0.83 0.8261 0.9227 3178646 Maybridge4_001421 CN(C(=O)c1c(C)onc1c2c(Cl)cccc2Cl)c3nnc(s3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A14 compound treatment 0.199 -0.0162 -0.23 0.235 0.0183 0.31 0.0537 0.1392 3063627 Maybridge4_001422 N#Cc1sc2nc3ccccc3n2c1/N=C/N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A15 compound treatment 0.245 0.0298 0.43 0.201 -0.0157 -0.26 0.1154 0.2306 3178647 Maybridge4_001423 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)Oc3ccccc3N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A16 compound treatment 0.191 -0.0242 -0.35 0.218 0.00134 0.02 -0.229 -0.6597 1004868 Maybridge4_001424 Sc1ncnc2n(ncc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A17 compound treatment 0.201 -0.0142 -0.2 0.23 0.0133 0.22 0.0146 0.0481 1225276 Maybridge4_001425 COc1ccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccc(cc3)C(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A18 compound treatment 0.218 0.00278 0.04 0.306 0.0893 1.5 1.0885 0.7256 1212340 Maybridge4_001426 COc1ccc(cc1)C(=O)Nc2ccc(nc2)N3CCN(CC3)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A19 compound treatment 0.093 -0.122 -1.75 0.121 -0.0957 -1.61 -2.3714 -0.9991 1490823 Maybridge4_001427 Fc1ccc(cc1)c2cn3cccc(OCc4ccc(Cl)c(Cl)c4)c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A20 compound treatment 0.218 0.00278 0.04 0.246 0.0293 0.49 0.3764 0.7617 1164040 Maybridge4_001428 Oc1ccccc1C(=O)Nc2ccc(NC(=O)Nc3ccccc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A21 compound treatment 0.215 -2.19E-4 0.0 0.229 0.0123 0.21 0.1443 0.6963 1589639 Maybridge4_001429 O=C(Nc1ccc(OCc2ccccc2)cc1)N3CCN(CC3)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A22 compound treatment 0.207 -0.00822 -0.12 0.231 0.0143 0.24 0.0871 0.3251 1548910 Maybridge4_001430 CCOC(=O)Cc1csc(NS(=O)(=O)c2cn(C)cn2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A23 mock treatment 0.202 -0.0132 -0.19 0.183 -0.0337 -0.56 -0.5331 -0.895 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 A24 mock treatment 0.215 -2.19E-4 0.0 0.195 -0.0217 -0.36 -0.2592 -0.7132 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B01 compound treatment 0.217 0.00178 0.03 0.219 0.00234 0.04 0.0458 0.9779 3178648 Maybridge4_001431 Clc1ccc2c(Oc3ccc(NS(=O)(=O)c4ccc(s4)c5ccccn5)cn3)ncnc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B02 compound treatment 0.217 0.00178 0.03 0.207 -0.00966 -0.16 -0.0966 -0.5887 3178649 Maybridge4_001432 O=C(c1sc(Nc2ccc3OCCOc3c2)nc1c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B03 compound treatment 0.243 0.0278 0.4 0.225 0.00834 0.14 0.38 0.9019 1669153 Maybridge4_001433 CCc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B04 compound treatment 0.244 0.0288 0.41 0.27 0.0533 0.9 0.9242 0.9378 3178650 Maybridge4_001434 O=C(NCc1ccsc1)c2ccc3OCCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B05 compound treatment 0.253 0.0378 0.54 0.263 0.0463 0.78 0.9321 0.9842 3063628 Maybridge4_001435 CCc1c(nnc2cc(C)nn12)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B06 compound treatment 0.226 0.0108 0.15 0.259 0.0423 0.71 0.6116 0.841 1347207 Maybridge4_001436 COc1ccc(Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B07 compound treatment 0.23 0.0148 0.21 0.236 0.0193 0.32 0.3791 0.9784 1134750 Maybridge4_001437 CC(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B08 compound treatment 0.241 0.0258 0.37 0.271 0.0543 0.91 0.9057 0.9206 1513237 Maybridge4_001438 CSc1c2CCCCc2c(C#N)c3nc4ccccc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B09 compound treatment 0.227 0.0118 0.17 0.26 0.0433 0.73 0.6336 0.8484 3178651 Maybridge4_001439 Fc1ccc(cc1)S(=O)(=O)CCSc2nnc(OC(=O)c3cccs3)n2C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B10 compound treatment 0.24 0.0248 0.35 0.247 0.0303 0.51 0.6108 0.9843 3063629 Maybridge4_001440 N#Cc1c(/N=C/N2CCCCC2)nc3CCCCc3c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B11 compound treatment 0.238 0.0228 0.33 0.272 0.0553 0.93 0.8872 0.9013 3178652 Maybridge4_001441 COC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B12 compound treatment 0.232 0.0168 0.24 0.242 0.0253 0.43 0.4705 0.9633 3063630 Maybridge4_001442 O=C(CN1C(=O)c2ccccc2S1(=O)=O)c3ccc4OCCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B13 compound treatment 0.215 -2.19E-4 0.0 0.264 0.0473 0.79 0.5597 0.7043 1504288 Maybridge4_001443 COc1ccc(cc1)C(=O)Nc2ccc3[nH]ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B14 compound treatment 0.245 0.0298 0.43 0.279 0.0623 1.05 1.0411 0.9215 1589222 Maybridge4_001444 OC(=O)CCC(=O)NCC1COc2ccccc2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B15 compound treatment 0.243 0.0278 0.4 0.232 0.0153 0.26 0.4631 0.978 1127725 Maybridge4_001445 CCOC(=O)c1nn(c2ccccc2)c3nc(Nc4ccc(C)cc4)cc(=O)n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B16 compound treatment 0.069 -0.146 -2.09 0.064 -0.153 -2.56 -3.2906 -0.9949 1720808 Maybridge4_001446 O=C(CSc1ccccc1)N2c3ccccc3Sc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B17 compound treatment 0.226 0.0108 0.15 0.251 0.0343 0.58 0.5166 0.8658 1598554 Maybridge4_001447 COc1ccc(cc1)C(=O)c2c(NC(=O)C)sc3CN(CCc23)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B18 compound treatment 0.212 -0.00322 -0.05 0.289 0.0723 1.21 0.826 0.6798 3063652 Maybridge4_001448 C/C(=N\O)/C(C)(C)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B19 compound treatment 0.231 0.0158 0.23 0.257 0.0403 0.68 0.6384 0.8944 3063653 Maybridge4_001449 Oc1nnc(SCC(=O)c2ccc(cc2)N3CCOCC3)n1C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B20 compound treatment 0.224 0.00878 0.13 0.28 0.0633 1.06 0.8406 0.7852 3063654 Maybridge4_001450 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)Nc3ccccc3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B21 compound treatment 0.216 7.81E-4 0.01 0.264 0.0473 0.79 0.5698 0.717 3063655 Maybridge4_001451 Cc1cc2c(NC(=O)COCC(=O)O)cccc2nn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B22 compound treatment 0.24 0.0248 0.35 0.263 0.0463 0.78 0.8007 0.9367 3178653 Maybridge4_001452 CCOC(=O)N1CCC(CC1)NC(=O)c2snnc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B23 mock treatment 0.232 0.0168 0.24 0.226 0.00934 0.16 0.2806 0.9787 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 B24 mock treatment 0.225 0.00978 0.14 0.2 -0.0167 -0.28 -0.0987 -0.3159 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C01 compound treatment 0.246 0.0308 0.44 0.221 0.00434 0.07 0.3629 0.8131 3178654 Maybridge4_001453 COc1ccc(cc1)n2ccc(nc2=S)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C02 compound treatment 0.202 -0.0132 -0.19 0.238 0.0213 0.36 0.1196 0.2953 1547772 Maybridge4_001454 Cc1c(cnn1c2ccc(F)cc2)C(=O)NC3CCN(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C03 compound treatment 0.226 0.0108 0.15 0.182 -0.0347 -0.58 -0.3023 -0.5023 1661624 Maybridge4_001455 Cc1ccc(cc1)C(=O)Nc2ccc3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C04 compound treatment 0.246 0.0308 0.44 0.258 0.0413 0.69 0.802 0.9759 1628233 Maybridge4_001456 CCCCN1Cc2c(C1=O)n(CC(=O)c3ccc(OC)cc3)c4cc(nn4c2=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C05 compound treatment 0.26 0.0448 0.64 0.222 0.00534 0.09 0.5163 0.7983 1204335 Maybridge4_001457 O=C1N(CNc2ccccc2)C(=O)C3=C1CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C06 compound treatment 0.212 -0.00322 -0.05 0.265 0.0483 0.81 0.5412 0.6659 3178655 Maybridge4_001458 COc1ccccc1C2CCN(Cc3sc4ccccc4c3C)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C07 compound treatment 0.211 -0.00422 -0.06 0.235 0.0183 0.31 0.175 0.5579 1326929 Maybridge4_001459 Cc1ccc(cc1C)C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C08 compound treatment 0.233 0.0178 0.25 0.283 0.0663 1.11 0.9672 0.8468 1479015 Maybridge4_001460 O=C(Nc1ccccc1N2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C09 compound treatment 0.23 0.0148 0.21 0.27 0.0533 0.9 0.7826 0.8507 1487787 Maybridge4_001461 CCCc1cnc(nc1)N2CCN(CC2)S(=O)(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C10 compound treatment 0.22 0.00478 0.07 0.277 0.0603 1.01 0.7645 0.7531 3063656 Maybridge4_001462 Cn1cc(c(n1)C(F)(F)F)S(=O)(=O)Nc2ccccc2N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C11 compound treatment 0.286 0.0708 1.01 0.284 0.0673 1.13 1.5151 0.9985 3178656 Maybridge4_001463 COc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C12 compound treatment 0.244 0.0288 0.41 0.246 0.0293 0.49 0.6394 0.996 3063657 Maybridge4_001464 C(/N=C/1\S/C(=N/c2ccccc2)/C/3=C1/CCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C13 compound treatment 0.249 0.0338 0.48 0.272 0.0553 0.93 0.9985 0.9536 1606533 Maybridge4_001465 OC(=O)CC(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C14 compound treatment 0.217 0.00178 0.03 0.266 0.0493 0.83 0.6036 0.7285 3178742 Maybridge4_001466 Clc1ccc(/C=N/n2cnc3n(ncc3c2=N)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C15 compound treatment 0.187 -0.0282 -0.4 0.192 -0.0247 -0.41 -0.578 -0.9999 1551950 Maybridge4_001467 CCOC(=O)c1cn(nc1N)C(=O)CCSc2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C16 compound treatment 0.268 0.0528 0.75 0.206 -0.0107 -0.18 0.4074 0.5251 1274385 Maybridge4_001468 CCOC(=O)C1=C(N)Oc2c(C1c3ccccc3)c(=O)oc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C17 compound treatment 0.239 0.0238 0.34 0.229 0.0123 0.21 0.387 0.9717 1585094 Maybridge4_001469 O=S(=O)(N(CCC#N)Cc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C18 compound treatment 0.247 0.0318 0.45 0.224 0.00734 0.12 0.4086 0.8675 1144333 Maybridge4_001470 CC(C)(C)OC(=O)N1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C19 compound treatment 0.2 -0.0152 -0.22 0.273 0.0563 0.95 0.5148 0.5305 1395168 Maybridge4_001471 OC(=O)c1ccccc1C(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C20 compound treatment 0.192 -0.0232 -0.33 0.23 0.0133 0.22 -0.0765 -0.1909 3178743 Maybridge4_001472 Oc1nnc(SCC(=O)c2ccc3OCCOc3c2)n1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C21 compound treatment 0.202 -0.0132 -0.19 0.225 0.00834 0.14 -0.0347 -0.1474 1500505 Maybridge4_001473 CCOC(=O)c1cc(C)nc(N2CCC(CC2)C(=O)N)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C22 compound treatment 0.206 -0.00922 -0.13 0.198 -0.0187 -0.31 -0.3147 -0.9261 3178744 Maybridge4_001474 CCOC(=O)c1cnn(C(=O)c2snnc2C)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C23 mock treatment 0.207 -0.00822 -0.12 0.241 0.0243 0.41 0.2058 0.484 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 C24 mock treatment 0.194 -0.0212 -0.3 0.182 -0.0347 -0.58 -0.6259 -0.954 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D01 compound treatment 0.235 0.0198 0.28 0.229 0.0123 0.21 0.3466 0.9883 1160532 Maybridge4_001475 Clc1ccc2c(Oc3ccc(NC(=O)Nc4ccccc4)cn3)ncnc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D02 compound treatment 0.246 0.0308 0.44 0.243 0.0263 0.44 0.624 1.0 3063658 Maybridge4_001476 Oc1ccc(cc1O)C(=O)CN2C(=O)c3ccccc3S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D03 compound treatment 0.23 0.0148 0.21 0.217 3.44E-4 0.01 0.1536 0.7261 1237081 Maybridge4_001477 CN(C1CCCCC1)S(=O)(=O)c2ccc3ccccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D04 compound treatment 0.245 0.0298 0.43 0.281 0.0643 1.08 1.0649 0.9172 3063659 Maybridge4_001478 OC(CN1CCN(CC1)C2c3ccccc3-c4ccccc24)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D05 compound treatment 0.248 0.0328 0.47 0.208 -0.00866 -0.15 0.2288 0.4661 1413068 Maybridge4_001479 COC(=O)c1nn(c2ccccc2)c(=O)c3c(N)sc(C)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D06 compound treatment 0.223 0.00778 0.11 0.262 0.0453 0.76 0.6168 0.802 3178745 Maybridge4_001480 C(On1nnc2ccccc12)c3ccccc3COn4nnc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D07 compound treatment 0.272 0.0568 0.81 0.292 0.0753 1.26 1.4685 0.9771 3063660 Maybridge4_001481 CCN(C(=O)c1ccc2OCCc2c1)c3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D08 compound treatment 0.238 0.0228 0.33 0.317 0.1 1.68 1.4213 0.8286 1525376 Maybridge4_001482 CC(=O)N(C(=O)C)c1cc(C)c(C#N)c2nc3ccccc3n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D09 compound treatment 0.245 0.0298 0.43 0.249 0.0323 0.54 0.6851 0.9928 3063661 Maybridge4_001483 Cc1nnsc1c2nnc(SCC(=O)c3ccc(C)cc3)n2C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D10 compound treatment 0.216 7.81E-4 0.01 0.283 0.0663 1.11 0.7953 0.7142 1489082 Maybridge4_001484 Cn1c2ccccc2n3c(=O)cc(c(C#N)c13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D11 compound treatment 0.235 0.0198 0.28 0.301 0.0843 1.42 1.2011 0.832 1735545 Maybridge4_001485 CN(CCc1ccccn1)C(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D12 compound treatment 0.253 0.0378 0.54 0.287 0.0703 1.18 1.217 0.9372 3178746 Maybridge4_001486 Oc1ccccc1C(=O)NC(=O)c2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D13 compound treatment 0.262 0.0468 0.67 0.23 0.0133 0.22 0.6315 0.895 3178747 Maybridge4_001487 C1CCC(CC1)/N=C/2\S/C(=N\c3ccccc3)/C/4=C2/CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D14 compound treatment 0.265 0.0498 0.71 0.224 0.00734 0.12 0.5907 0.8174 3063662 Maybridge4_001488 OC(=O)CCCC(=O)N1CCN(CC1)c2ncccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D15 compound treatment 0.245 0.0298 0.43 0.319 0.102 1.72 1.5158 0.8565 1539797 Maybridge4_001489 CCOC(=O)C1=NN(c2ccccc2)C3(C1c4ccc(C)cc4)C(=O)c5ccccc5C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D16 compound treatment 0.264 0.0488 0.7 0.3 0.0833 1.4 1.4825 0.9484 1582785 Maybridge4_001490 Cc1cc(C)c2c(n1)sc3c(=O)n(CC(=O)c4ccccc4)cnc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D17 compound treatment 0.237 0.0218 0.31 0.27 0.0533 0.9 0.8534 0.9002 3178748 Maybridge4_001491 OC(=O)c1ccc(cc1)c2cn3cccnc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D18 compound treatment 0.283 0.0678 0.97 0.268 0.0513 0.86 1.2949 0.9983 3063663 Maybridge4_001492 C/C(=N\O)/C(C)(C)Nc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D19 compound treatment 0.219 0.00378 0.05 0.249 0.0323 0.54 0.4221 0.7737 1236138 Maybridge4_001493 Cc1nc(Nc2ccccc2)sc1C(=O)c3cc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D20 compound treatment 0.259 0.0438 0.63 0.246 0.0293 0.49 0.7911 0.9929 3063664 Maybridge4_001494 FC(F)(F)c1ccccc1NS(=O)(=O)c2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D21 compound treatment 0.286 0.0708 1.01 0.25 0.0333 0.56 1.1116 0.9609 3178749 Maybridge4_001495 O=C(NCCN1CCNC1=O)c2ccc3nccnc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D22 compound treatment 0.277 0.0618 0.88 0.27 0.0533 0.9 1.258 1.0 3178750 Maybridge4_001496 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D23 mock treatment 0.19 -0.0252 -0.36 0.258 0.0413 0.69 0.2356 0.3013 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 D24 mock treatment 0.179 -0.0362 -0.52 0.218 0.00134 0.02 -0.3504 -0.6757 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E01 compound treatment 0.208 -0.00722 -0.1 0.223 0.00634 0.11 0.0023 0.0153 3063665 Maybridge4_001497 Cc1ccc(cc1)c2ccn(c3ccc(C)c(Cl)c3)c(=S)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E02 compound treatment 0.202 -0.0132 -0.19 0.219 0.00234 0.04 -0.1059 -0.5483 1172555 Maybridge4_001498 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E03 compound treatment 0.237 0.0218 0.31 0.288 0.0713 1.2 1.067 0.8624 1326393 Maybridge4_001499 OC(=O)c1ccccc1C(=O)N2CCN(Cc3ccncc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E04 compound treatment 0.277 0.0618 0.88 0.258 0.0413 0.69 1.1155 0.9928 1616068 Maybridge4_001500 Clc1ccccc1N2CCN(CC2)C3=Cc4ccccc4CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E05 compound treatment 0.26 0.0448 0.64 0.231 0.0143 0.24 0.6232 0.9107 1429251 Maybridge4_001501 O=C(NC1CCCc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E06 compound treatment 0.251 0.0358 0.51 0.265 0.0483 0.81 0.9356 0.9753 1274546 Maybridge4_001502 Cc1c(CN2CCc3ccccc3C2)sc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E07 compound treatment 0.268 0.0528 0.75 0.274 0.0573 0.96 1.2144 0.9928 1237910 Maybridge4_001503 O=C(Nc1ccc(CN2CCS(=O)(=O)CC2)cc1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E08 compound treatment 0.277 0.0618 0.88 0.269 0.0523 0.88 1.2461 1.0 1710600 Maybridge4_001504 Cn1cnc(c1)S(=O)(=O)Nc2ccccc2N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E09 compound treatment 0.293 0.0778 1.11 0.285 0.0683 1.15 1.5978 0.9999 1424693 Maybridge4_001505 Cc1ccc(NC(=O)N(CCC(=O)O)Cc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E10 compound treatment 0.25 0.0348 0.5 0.25 0.0333 0.56 0.7475 0.9983 1251028 Maybridge4_001506 CC(C)(C)c1cn2cccc(OCc3ccc(Cl)c(Cl)c3)c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E11 compound treatment 0.241 0.0258 0.37 0.244 0.0273 0.46 0.5853 0.9941 1143941 Maybridge4_001507 O=S(=O)(NC1CCCc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E12 compound treatment 0.257 0.0418 0.6 0.264 0.0473 0.79 0.9845 0.9901 3178751 Maybridge4_001508 Nc1c(cnn1c2ccccc2)c3n[nH]c(=S)n3c4ccc(Cl)cc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E13 compound treatment 0.258 0.0428 0.61 0.205 -0.0117 -0.2 0.2944 0.4582 3063666 Maybridge4_001509 FC(F)(F)c1ccn(n1)c2ccc(NC(=O)Nc3ccccc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E14 compound treatment 0.311 0.0958 1.37 0.27 0.0533 0.9 1.6018 0.9787 3178752 Maybridge4_001510 CCOC(=O)COc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E15 compound treatment 0.245 0.0298 0.43 0.263 0.0463 0.78 0.8512 0.9598 1607723 Maybridge4_001511 CCOC(=O)c1cnn(C(=O)c2c(C)nc3ccccn23)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E16 compound treatment 0.193 -0.0222 -0.32 0.221 0.00434 0.07 -0.1732 -0.5311 1572679 Maybridge4_001512 Cc1nn(c2ccccc2)c3[nH]c(=O)c(C#N)c(c4cccs4)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E17 compound treatment 0.231 0.0158 0.23 0.288 0.0713 1.2 1.0063 0.8259 1609957 Maybridge4_001513 O=S(=O)(N(CCC#N)CCc1ccccn1)c2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E18 compound treatment 0.247 0.0318 0.45 0.229 0.0123 0.21 0.4679 0.9367 1377637 Maybridge4_001514 S=C(Nc1ccc2OCCOc2c1)Nc3ccccc3N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E19 compound treatment 0.24 0.0248 0.35 0.238 0.0213 0.36 0.504 1.0 1175800 Maybridge4_001515 OC(=O)CCC(=O)NC1CCCCNC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E20 compound treatment 0.196 -0.0192 -0.27 0.203 -0.0137 -0.23 -0.3565 -0.9959 1593716 Maybridge4_001516 CC(c1ccccc1)n2c(O)nnc2SCc3cc(=O)oc4cc(O)ccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E21 compound treatment 0.208 -0.00722 -0.1 0.234 0.0173 0.29 0.1328 0.43 1417192 Maybridge4_001517 CCOC(=O)C1CCN(CC1)C(=O)c2ccc(CC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E22 compound treatment 0.225 0.00978 0.14 0.223 0.00634 0.11 0.1742 0.9909 3063667 Maybridge4_001518 Cc1nnsc1c2nnc(SCC(=O)N(C3CCCCC3)c4ccccc4)n2C5CC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E23 mock treatment 0.206 -0.00922 -0.13 0.237 0.0203 0.34 0.1482 0.4049 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 E24 mock treatment 0.183 -0.0322 -0.46 0.202 -0.0147 -0.25 -0.4998 -0.9568 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F01 compound treatment 0.249 0.0338 0.48 0.233 0.0163 0.27 0.5356 0.964 1399434 Maybridge4_001519 Cc1ccc(cc1)C(O)COC2=NCNc3cc(Cl)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F02 compound treatment 0.227 0.0118 0.17 0.212 -0.00466 -0.08 0.0639 0.344 3063693 Maybridge4_001520 Clc1ccc(c(Cl)c1)S(=O)(=O)CCN2C(=O)c3ccccc3S2(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F03 compound treatment 0.218 0.00278 0.04 0.283 0.0663 1.11 0.8155 0.7319 1228123 Maybridge4_001521 COC(=O)c1cc(oc1C)S(=O)(=O)N(C)C2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F04 compound treatment 0.242 0.0268 0.38 0.265 0.0483 0.81 0.8446 0.9413 3063694 Maybridge4_001522 Cc1nc(sc1c2nnc(o2)c3cccc4ccccc34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F05 compound treatment 0.248 0.0328 0.47 0.286 0.0693 1.16 1.1545 0.9201 1500694 Maybridge4_001523 CC(=O)Nc1cc(nn(c2ccccc2)c1=O)C(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F06 compound treatment 0.258 0.0428 0.61 0.299 0.0823 1.38 1.41 0.9328 3063695 Maybridge4_001524 S=c1[nH]nc(c2ccncc2)n1/N=C/c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F07 compound treatment 0.276 0.0608 0.87 0.292 0.0753 1.26 1.5089 0.9833 1217417 Maybridge4_001525 CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1C(=O)c4ccccc4C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F08 compound treatment 0.276 0.0608 0.87 0.309 0.0923 1.55 1.7107 0.9626 1688932 Maybridge4_001526 NNC(=O)Cn1nc(c2ccccc2)c(c(C#N)c1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F09 compound treatment 0.259 0.0438 0.63 0.271 0.0543 0.91 1.0878 0.9832 3178837 Maybridge4_001527 CCc1cc(C(=O)c2ccc(OC)cc2)c(NC(=O)c3ccc(cc3)C(F)(F)F)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F10 compound treatment 0.261 0.0458 0.65 0.234 0.0173 0.29 0.6689 0.9334 1686628 Maybridge4_001528 NNC(=O)c1oc2nc(cc(c3ccccc3)c2c1N)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F11 compound treatment 0.233 0.0178 0.25 0.28 0.0633 1.06 0.9316 0.8522 1119276 Maybridge4_001529 CN(CCc1ccccn1)C(=O)NS(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F12 compound treatment 0.263 0.0478 0.68 0.337 0.12 2.02 1.9115 0.8964 3063696 Maybridge4_001530 Fc1ccc(cc1)C(=O)CN2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F13 compound treatment 0.247 0.0318 0.45 0.243 0.0263 0.44 0.6341 0.9999 1398696 Maybridge4_001531 Cn1c(SCc2n[nH]c(=S)n2CC=C)nnc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F14 compound treatment 0.268 0.0528 0.75 0.222 0.00534 0.09 0.5973 0.7856 3063697 Maybridge4_001532 OC(=O)c1ccccc1C(=O)N2CCN(CC2)c3ncccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F15 compound treatment 0.26 0.0448 0.64 0.231 0.0143 0.24 0.6232 0.9107 3178838 Maybridge4_001533 Fc1ccc(cc1)C(=O)COc2nnc(SCCS(=O)(=O)c3ccc(F)cc3)n2C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F16 compound treatment 0.297 0.0818 1.17 0.23 0.0133 0.22 0.9855 0.8275 3063698 Maybridge4_001534 O=C/1N(Cc2ccccc2)c3ccccc3\C1=N\c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F17 compound treatment 0.262 0.0468 0.67 0.267 0.0503 0.84 1.0706 0.9933 3178839 Maybridge4_001535 CCOC(=O)C1=NN(C(=C2C(=O)c3ccccc3C2=O)C1c4cccs4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F18 compound treatment 0.272 0.0568 0.81 0.224 0.00734 0.12 0.6615 0.8052 3063699 Maybridge4_001536 COc1ccc(cc1OC)C(=O)NC(=O)c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F19 compound treatment 0.287 0.0718 1.03 0.284 0.0673 1.13 1.5253 0.9988 1600649 Maybridge4_001537 O=C(N1CCOCC1)c2ccc3OCCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F20 compound treatment 0.24 0.0248 0.35 0.227 0.0103 0.17 0.3734 0.9461 3063700 Maybridge4_001538 CCN(c1cccc2ccccc12)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F21 compound treatment 0.253 0.0378 0.54 0.284 0.0673 1.13 1.1814 0.943 3178840 Maybridge4_001539 O=C(NCCc1ccccn1)c2ccc3nccnc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F22 compound treatment 0.314 0.0988 1.41 0.23 0.0133 0.22 1.1575 0.8091 3178841 Maybridge4_001540 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2cccnc2Oc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F23 mock treatment 0.238 0.0228 0.33 0.27 0.0533 0.9 0.8635 0.9063 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 F24 mock treatment 0.194 -0.0212 -0.3 0.204 -0.0127 -0.21 -0.3648 -0.9848 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G01 compound treatment 0.232 0.0168 0.24 0.217 3.44E-4 0.01 0.1738 0.7239 3063701 Maybridge4_001541 COc1ccc(cc1n2ccc(nc2=S)c3ccc(C)cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G02 compound treatment 0.221 0.00578 0.08 0.245 0.0283 0.48 0.3949 0.8178 1377005 Maybridge4_001542 Cc1ccc(cc1C)C(=O)Nc2ccc(cc2)c3cn4CCSc4n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G03 compound treatment 0.193 -0.0222 -0.32 0.231 0.0143 0.24 -0.0545 -0.1367 1733649 Maybridge4_001543 CC(C)c1ccc(NC(=O)CSCc2csc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G04 compound treatment 0.264 0.0488 0.7 0.258 0.0413 0.69 0.9841 1.0 1177034 Maybridge4_001544 Cc1ccc(cc1)n2nnnc2c3c[nH]c4cc(Cl)c(F)cc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G05 compound treatment 0.304 0.0888 1.27 0.282 0.0653 1.1 1.6735 0.9973 3178842 Maybridge4_001545 Clc1ccc2OCC(=Cc2c1)C(=O)NC3CCCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G06 compound treatment 0.281 0.0658 0.94 0.247 0.0303 0.51 1.0254 0.9584 1406389 Maybridge4_001546 CCCCc1ccc(NC(=O)Nc2ccc(cc2)N3CCCCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G07 compound treatment 0.293 0.0778 1.11 0.252 0.0353 0.59 1.2062 0.9566 1501125 Maybridge4_001547 Cc1nnsc1C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G08 compound treatment 0.318 0.103 1.47 0.24 0.0233 0.39 1.3166 0.8654 3063702 Maybridge4_001548 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cc(sc2C(F)(F)F)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G09 compound treatment 0.247 0.0318 0.45 0.268 0.0513 0.86 0.9308 0.9553 1046775 Maybridge4_001549 O=C1CCN(Cc2ccccc2)C(=O)N1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G10 compound treatment 0.248 0.0328 0.47 0.28 0.0633 1.06 1.0833 0.9323 1245508 Maybridge4_001550 Clc1ccc(Cl)c(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G11 compound treatment 0.23 0.0148 0.21 0.277 0.0603 1.01 0.8657 0.8367 3063703 Maybridge4_001551 COc1ccc(OCC2CN=C(Nc3ccc(C)cc3)S2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G12 compound treatment 0.265 0.0498 0.71 0.264 0.0473 0.79 1.0654 0.9985 3178843 Maybridge4_001552 Clc1ccc(/C=N/n2cnc3n(ncc3c2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G13 compound treatment 0.3 0.0848 1.21 0.229 0.0123 0.21 1.004 0.8161 3063704 Maybridge4_001553 CC(C)N(CCC#N)C(=O)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G14 compound treatment 0.197 -0.0182 -0.26 0.195 -0.0217 -0.36 -0.4413 -0.9867 1165894 Maybridge4_001554 Cn1c(SCC=C)nnc1c2oc3nc(cc(c4ccccc4)c3c2N)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G15 compound treatment 0.246 0.0308 0.44 0.278 0.0613 1.03 1.0394 0.9282 3063705 Maybridge4_001555 Cc1ccc(cc1)C(O)CSc2nnc(c3ccc4ccccc4c3)n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G16 compound treatment 0.258 0.0428 0.61 0.254 0.0373 0.63 0.8759 0.9999 3178844 Maybridge4_001556 CC1CCc2c(C1)sc3ncn(CC=C)c(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G17 compound treatment 0.249 0.0338 0.48 0.255 0.0383 0.64 0.7967 0.99 1415511 Maybridge4_001557 CC(C)c1ccc(NC(=O)COc2ncnc3cc(Cl)ccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G18 compound treatment 0.26 0.0448 0.64 0.244 0.0273 0.46 0.7774 0.9866 3063706 Maybridge4_001558 CN(C1CCCCC1)C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G19 compound treatment 0.265 0.0498 0.71 0.222 0.00534 0.09 0.5669 0.7899 1222950 Maybridge4_001559 COc1ccc(Cc2nnc(SCC3CC3)n2c4ccc(F)cc4)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G20 compound treatment 0.238 0.0228 0.33 0.205 -0.0117 -0.2 0.0921 0.2423 3063707 Maybridge4_001560 Oc1nnc(SCc2cc(=O)oc3cc(O)ccc23)n1Cc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G21 compound treatment 0.233 0.0178 0.25 0.225 0.00834 0.14 0.2789 0.9605 1138850 Maybridge4_001561 CCOC(=O)C1CCN(CC1)C(=O)C2Cc3ccccc3N2C(=O)OCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G22 compound treatment 0.221 0.00578 0.08 0.225 0.00834 0.14 0.1575 0.9684 3063708 Maybridge4_001562 O=S(=O)(Nc1ccccc1C#N)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G23 mock treatment 0.195 -0.0202 -0.29 0.196 -0.0207 -0.35 -0.4496 -0.9959 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 G24 mock treatment 0.218 0.00278 0.04 0.172 -0.0447 -0.75 -0.5019 -0.6686 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H01 compound treatment 0.207 -0.00822 -0.12 0.284 0.0673 1.13 0.7161 0.6302 3178845 Maybridge4_001563 Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H02 compound treatment 0.232 0.0168 0.24 0.248 0.0313 0.53 0.5417 0.9368 3063709 Maybridge4_001564 Cc1noc(C)c1c2nc(CN3C(=O)c4ccccc4S3(=O)=O)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H03 compound treatment 0.236 0.0208 0.3 0.257 0.0403 0.68 0.689 0.9317 3178846 Maybridge4_001565 OC(=O)COCC(=O)Nc1ccc(Oc2cccc(c2)C(F)(F)F)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H04 compound treatment 0.237 0.0218 0.31 0.286 0.0693 1.16 1.0433 0.8659 1968939 Maybridge4_001566 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H05 compound treatment 0.28 0.0648 0.93 0.208 -0.00866 -0.15 0.5525 0.589 3178847 Maybridge4_001567 COC(=O)C1N(N=C(C=C1C(=O)OC)C(=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H06 compound treatment 0.235 0.0198 0.28 0.272 0.0553 0.93 0.8569 0.8825 1661945 Maybridge4_001568 Clc1cccc(NC(=O)N2CCCn3c(SCC=C)nnc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H07 compound treatment 0.238 0.0228 0.33 0.284 0.0673 1.13 1.0297 0.8753 3178848 Maybridge4_001569 Oc1nnc(SCC(=O)Nc2ccccc2)n1Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H08 compound treatment 0.312 0.0968 1.38 0.262 0.0453 0.76 1.517 0.9603 1169532 Maybridge4_001570 NNC(=O)CN1c2ccccc2Sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H09 compound treatment 0.241 0.0258 0.37 0.224 0.00734 0.12 0.3479 0.8948 3178849 Maybridge4_001571 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)NC3Cc4ccccc4C3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H10 compound treatment 0.256 0.0408 0.58 0.251 0.0343 0.58 0.8201 1.0 3063710 Maybridge4_001572 N#Cc1sc2nc3ccccc3n2c1/N=C/c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H11 compound treatment 0.27 0.0548 0.78 0.229 0.0123 0.21 0.7006 0.8644 1394169 Maybridge4_001573 O=C(Nc1ccc(OCc2ccccc2)cc1)N3CCN(CC3)C(=O)C4COc5ccccc5O4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H12 compound treatment 0.301 0.0858 1.23 0.274 0.0573 0.96 1.5482 0.9928 3063711 Maybridge4_001574 O=C1Nc2ccccc2C1Cc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H13 compound treatment 0.281 0.0658 0.94 0.236 0.0193 0.32 0.8949 0.8991 1163008 Maybridge4_001575 S=C(Nc1ccccc1)C(C#N)c2nc3ccccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H14 compound treatment 0.262 0.0468 0.67 0.298 0.0813 1.37 1.4386 0.9461 3063712 Maybridge4_001576 NS(=O)(=O)c1ccc(cc1)N(S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H15 compound treatment 0.242 0.0268 0.38 0.254 0.0373 0.63 0.7141 0.9721 3178934 Maybridge4_001577 CC(C)(C)c1ccc(cc1)c2noc(CSc3nnc(O)n3c4cccnc4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H16 compound treatment 0.337 0.122 1.74 0.277 0.0603 1.01 1.9479 0.9667 1688554 Maybridge4_001578 CCNc1nc(SCC(=O)OCC)nc2sc3CC(C)CCc3c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H17 compound treatment 0.247 0.0318 0.45 0.217 3.44E-4 0.01 0.3255 0.716 1408340 Maybridge4_001579 O=C1c2ccccc2-c3c1cnc4c(cnn34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H18 compound treatment 0.279 0.0638 0.91 0.243 0.0263 0.44 0.9577 0.9447 3063713 Maybridge4_001580 O=C(NCC1CC1)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H19 compound treatment 0.143 -0.0722 -1.03 0.14 -0.0767 -1.29 -1.6402 -0.9941 1279297 Maybridge4_001581 Cc1ccc(Oc2ncccc2NC(=O)Nc3ccccc3)c4CCCc41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H20 compound treatment 0.225 0.00978 0.14 0.226 0.00934 0.16 0.2098 0.9984 3178935 Maybridge4_001582 Cn1cnc(c1)S(=O)(=O)N(Cc2ccccc2)Cc3ccccc3N4CCC(CC4)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H21 compound treatment 0.267 0.0518 0.74 0.279 0.0623 1.05 1.2636 0.9857 3063714 Maybridge4_001583 CC(c1ccccc1)n2c(O)nnc2SCC(=O)c3csc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H22 compound treatment 0.254 0.0388 0.55 0.263 0.0463 0.78 0.9423 0.9863 3178936 Maybridge4_001584 C1C(=Nc2ccccc2N=C1c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H23 mock treatment 0.209 -0.00622 -0.09 0.234 0.0173 0.29 0.1429 0.4696 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 H24 mock treatment 0.194 -0.0212 -0.3 0.199 -0.0177 -0.3 -0.4242 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I01 compound treatment 0.21 -0.00522 -0.07 0.242 0.0253 0.43 0.248 0.5742 3063715 Maybridge4_001585 Fc1ccc(cc1)c2oncc2c3nnnn3c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I02 compound treatment 0.227 0.0118 0.17 0.262 0.0453 0.76 0.6573 0.8433 1145291 Maybridge4_001586 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)c4ccc5nonc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I03 compound treatment 0.28 0.0648 0.93 0.265 0.0483 0.81 1.229 0.9978 1583736 Maybridge4_001587 Cc1ccc(cc1)S(=O)(=O)NC(=O)NC2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I04 compound treatment 0.159 -0.0562 -0.8 0.153 -0.0637 -1.07 -1.3241 -0.9902 1281751 Maybridge4_001588 CN(CC(=O)O)c1ncc(c2nnnn2c3ccccc3)c(n1)c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I05 compound treatment 0.288 0.0728 1.04 0.196 -0.0207 -0.35 0.491 0.4475 3178937 Maybridge4_001589 Cc1nc(ccc1C(=O)Oc2ccccc2N3CCCCC3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I06 compound treatment 0.299 0.0838 1.2 0.253 0.0363 0.61 1.2787 0.9509 1529830 Maybridge4_001590 Clc1cccc(NC(=O)Nc2ccc(cc2)N3CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I07 compound treatment 0.258 0.0428 0.61 0.233 0.0163 0.27 0.6267 0.9345 1741796 Maybridge4_001591 Cc1cc(no1)C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I08 compound treatment 0.281 0.0658 0.94 0.185 -0.0317 -0.53 0.2896 0.268 1155868 Maybridge4_001592 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc3ccccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I09 compound treatment 0.242 0.0268 0.38 0.213 -0.00366 -0.06 0.2275 0.5864 1382929 Maybridge4_001593 COc1ccc(cc1)C(=O)N2CCc3cc(OC)c(OC)cc3C2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I10 compound treatment 0.257 0.0418 0.6 0.273 0.0563 0.95 1.0913 0.9755 3178938 Maybridge4_001594 CC(C)(C)c1cc(NC(=O)Nc2ccccc2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I11 compound treatment 0.305 0.0898 1.28 0.22 0.00334 0.06 0.9478 0.7373 3063716 Maybridge4_001595 Cc1nc(ccc1C(=O)NCC(O)c2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I12 compound treatment 0.276 0.0608 0.87 0.252 0.0353 0.59 1.0342 0.9826 3178939 Maybridge4_001596 Cn1c(CSc2nnc(c3ccccc3)n2CC=C)nnc1SCc4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I13 compound treatment 0.262 0.0468 0.67 0.271 0.0543 0.91 1.1181 0.9884 3063717 Maybridge4_001597 CC(C)N1CCC(=O)N(C1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I14 compound treatment 0.236 0.0208 0.3 0.278 0.0613 1.03 0.9382 0.8755 1303953 Maybridge4_001598 O=c1[nH]cnc2n(c3ccccc3)c(=S)sc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I15 compound treatment 0.256 0.0408 0.58 0.231 0.0143 0.24 0.5827 0.9234 1733519 Maybridge4_001599 Cc1nc2ccccn2c1c3ccnc(SCC(=O)N(C4CCCCC4)c5ccccc5)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I16 compound treatment 0.23 0.0148 0.21 0.227 0.0103 0.17 0.2723 0.9952 1465542 Maybridge4_001600 Cc1ccc(cc1)C(=O)CN(Cc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I17 compound treatment 0.192 -0.0232 -0.33 0.177 -0.0397 -0.67 -0.7055 -0.9484 3063736 Maybridge4_001601 OC(=O)CC(CC(=O)Oc1ccccc1N2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I18 compound treatment 0.21 -0.00522 -0.07 0.155 -0.0617 -1.03 -0.7845 -0.7561 3063737 Maybridge4_001602 CC(C)N(Cc1ccccc1)C(=O)Nc2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I19 compound treatment 0.253 0.0378 0.54 0.207 -0.00966 -0.16 0.2675 0.4742 1622159 Maybridge4_001603 COc1ccc(Cc2nnc(SCC(=O)NC(C)C)n2c3ccc(F)cc3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I20 compound treatment 0.249 0.0338 0.48 0.195 -0.0217 -0.36 0.0847 0.14 3063738 Maybridge4_001604 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCCS(=O)(=O)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I21 compound treatment 0.277 0.0618 0.88 0.213 -0.00366 -0.06 0.5815 0.6564 1522253 Maybridge4_001605 CCOC(=O)C1CCN(CC1)C(=O)c2sc(nc2C)c3ccc4OCCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I22 compound treatment 0.189 -0.0262 -0.38 0.279 0.0623 1.05 0.4747 0.4271 3063739 Maybridge4_001606 O=S(=O)(Nc1ccccc1N2CCCCC2)c3cccc4nonc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I23 mock treatment 0.194 -0.0212 -0.3 0.21 -0.00666 -0.11 -0.2936 -0.9078 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 I24 mock treatment 0.167 -0.0482 -0.69 0.257 0.0403 0.68 -0.0089 -0.0092 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J01 compound treatment 0.216 7.81E-4 0.01 0.212 -0.00466 -0.08 -0.0474 -0.5999 1381618 Maybridge4_001607 CC(C)c1ccc(NC(=O)CSc2nnc(O)n2C(C)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J02 compound treatment 0.242 0.0268 0.38 0.283 0.0663 1.11 1.0582 0.8987 3063740 Maybridge4_001608 Cc1onc(c1CN2C(=O)c3ccccc3S2(=O)=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J03 compound treatment 0.149 -0.0662 -0.95 0.123 -0.0937 -1.57 -1.7813 -0.9706 1310898 Maybridge4_001609 Clc1cccc(NC(=O)Nc2ccccc2N3CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J04 compound treatment 0.245 0.0298 0.43 0.161 -0.0557 -0.93 -0.3593 -0.35 1473794 Maybridge4_001610 Fc1cn(Cc2c(Cl)cccc2Cl)c(=O)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J05 compound treatment 0.256 0.0408 0.58 0.243 0.0263 0.44 0.7251 0.9907 1148553 Maybridge4_001611 CCOC(=O)c1nn(c2ccccc2)c(=O)c3c(N)c(C#N)c(cc13)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J06 compound treatment 0.292 0.0768 1.1 0.241 0.0243 0.41 1.0655 0.9093 2101411 Maybridge4_001612 O=C(Oc1c(C#N)sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c12)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J07 compound treatment 0.244 0.0288 0.41 0.277 0.0603 1.01 1.0073 0.9213 1624521 Maybridge4_001613 CC(c1ccccc1)n2c(OC(=O)N(C)C)nnc2SCC(=O)c3ccc4OCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J08 compound treatment 0.278 0.0628 0.9 0.224 0.00734 0.12 0.7221 0.7967 3063741 Maybridge4_001614 CCOC(=O)c1cnn(c1NC(=O)Nc2cccc(Cl)c2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J09 compound treatment 0.227 0.0118 0.17 0.238 0.0213 0.36 0.3725 0.9408 3063742 Maybridge4_001615 Cc1cc(C)cc(OC(=O)c2ccc(Oc3cc(Cl)cc(Cl)c3)o2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J10 compound treatment 0.286 0.0708 1.01 0.274 0.0573 0.96 1.3965 0.9997 1606613 Maybridge4_001616 COc1cc(OC)c2nc(C)c3CN(Cc3c2c1)C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J11 compound treatment 0.27 0.0548 0.78 0.242 0.0253 0.43 0.8549 0.9588 3178940 Maybridge4_001617 CN(C(=O)c1nn(nc1C)c2ccccc2)c3nnc(s3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J12 compound treatment 0.311 0.0958 1.37 0.277 0.0603 1.01 1.6849 0.9889 3063743 Maybridge4_001618 Cc1sc(nc1c2ccccc2)c3ccc(cc3)c4csnn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J13 compound treatment 0.253 0.0378 0.54 0.251 0.0343 0.58 0.7897 0.9995 3178941 Maybridge4_001619 S=c1[nH]nc(CCCCc2n[nH]c(=S)[nH]2)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J14 compound treatment 0.29 0.0748 1.07 0.238 0.0213 0.36 1.0097 0.8951 3063744 Maybridge4_001620 O=C(Nc1ccccc1N2CCOCC2)C3=NNC(=O)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J15 compound treatment 0.292 0.0768 1.1 0.291 0.0743 1.25 1.6589 0.998 3178942 Maybridge4_001621 Cc1c(sc2ccc(Cl)cc12)C(=O)CSc3nnc(O)n3C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J16 compound treatment 0.289 0.0738 1.06 0.258 0.0413 0.69 1.2369 0.9793 1671368 Maybridge4_001622 O=C(CSc1nnc(o1)c2ccncc2)N3c4ccccc4Sc5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J17 compound treatment 0.266 0.0508 0.73 0.288 0.0713 1.2 1.3603 0.9713 3178943 Maybridge4_001623 CC(C)(C)c1cc(N/C=C/C(=O)c2ccc(Cl)cc2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J18 compound treatment 0.25 0.0348 0.5 0.201 -0.0157 -0.26 0.166 0.295 3178944 Maybridge4_001624 O=C(C1=NOC2(C1c3ccccc3)C(=O)c4ccccc4C2=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J19 compound treatment 0.266 0.0508 0.73 0.229 0.0123 0.21 0.6601 0.8739 1576744 Maybridge4_001625 Cc1ccc(Oc2ncccc2NC(=O)CC(CC(=O)O)c3ccccc3)c4CCCc41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J20 compound treatment 0.289 0.0738 1.06 0.279 0.0623 1.05 1.4861 1.0 1506454 Maybridge4_001626 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J21 compound treatment 0.155 -0.0602 -0.86 0.132 -0.0847 -1.42 -1.6138 -0.9712 3178945 Maybridge4_001627 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCC(=O)c3ccc(C#N)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J22 compound treatment 0.265 0.0498 0.71 0.245 0.0283 0.48 0.8399 0.9808 3063745 Maybridge4_001628 OC(=O)CSCC(=O)Nc1n[nH]c(SCc2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J23 mock treatment 0.254 0.0388 0.55 0.251 0.0343 0.58 0.7998 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 J24 mock treatment 0.212 -0.00322 -0.05 0.189 -0.0277 -0.46 -0.3608 -0.7734 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K01 compound treatment 0.233 0.0178 0.25 0.244 0.0273 0.46 0.5044 0.9612 3178946 Maybridge4_001629 Cc1ccccc1c2oncc2c3nnnn3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K02 compound treatment 0.235 0.0198 0.28 0.265 0.0483 0.81 0.7738 0.9005 1125361 Maybridge4_001630 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(cc2)c3cn4CCSc4n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K03 compound treatment 0.273 0.0578 0.83 0.279 0.0623 1.05 1.3243 0.9932 1429606 Maybridge4_001631 CC(C)(C)c1ccc(NC(=O)NC2CCCc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K04 compound treatment 0.259 0.0438 0.63 0.273 0.0563 0.95 1.1115 0.98 1237562 Maybridge4_001632 CCOC(=O)C1CCCN(C1)C(=O)S(=O)(=O)c2ccc(s2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K05 compound treatment 0.268 0.0528 0.75 0.248 0.0313 0.53 0.9058 0.9844 3063746 Maybridge4_001633 Cc1ccc(cc1)S(=O)(=O)NC(=O)Oc2ccccc2N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K06 compound treatment 0.308 0.0928 1.33 0.255 0.0383 0.64 1.3935 0.9448 1225155 Maybridge4_001634 O=S(=O)(Nc1ccc(cc1)N2CCCCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K07 compound treatment 0.27 0.0548 0.78 0.261 0.0443 0.74 1.0803 0.9997 1255708 Maybridge4_001635 Nc1ccccc1C(=O)NCCN2CCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K08 compound treatment 0.319 0.104 1.48 0.226 0.00934 0.16 1.1606 0.7775 1132174 Maybridge4_001636 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K09 compound treatment 0.168 -0.0472 -0.68 0.135 -0.0817 -1.37 -1.4467 -0.9468 1685251 Maybridge4_001637 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3nn(nc3C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K10 compound treatment 0.29 0.0748 1.07 0.241 0.0243 0.41 1.0453 0.9129 1481631 Maybridge4_001638 COc1ccc(cc1)C(=O)Nc2ccc(Oc3ncnc4cc(Cl)ccc34)nc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K11 compound treatment 0.239 0.0238 0.34 0.246 0.0293 0.49 0.5888 0.9837 1418693 Maybridge4_001639 OC(CNS(=O)(=O)c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K12 compound treatment 0.251 0.0358 0.51 0.208 -0.00866 -0.15 0.2592 0.4871 3179042 Maybridge4_001640 Clc1ccc(cc1)C(=O)CSc2nnc(CSc3nnc(c4ccccc4)n3CC=C)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K13 compound treatment 0.264 0.0488 0.7 0.252 0.0353 0.59 0.9128 0.9967 1429598 Maybridge4_001641 C(N1CCN(CC1)c2ccccn2)c3c[nH]c(n3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K14 compound treatment 0.293 0.0778 1.11 0.263 0.0463 0.78 1.3367 0.9847 1175807 Maybridge4_001642 C1Cc2nc3ncnn3c(N4CCN(CC4)c5ccccc5)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K15 compound treatment 0.248 0.0328 0.47 0.24 0.0233 0.39 0.6086 0.996 1227234 Maybridge4_001643 CCOC(=O)c1cc(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K16 compound treatment 0.253 0.0378 0.54 0.172 -0.0447 -0.75 -0.1479 -0.16 3179043 Maybridge4_001644 Cc1onc(NC(=O)CSCC(=O)O)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K17 compound treatment 0.207 -0.00822 -0.12 0.255 0.0383 0.64 0.3719 0.5685 1228665 Maybridge4_001645 O=C(Oc1ccccc1N2CCOCC2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K18 compound treatment 0.236 0.0208 0.3 0.224 0.00734 0.12 0.2973 0.924 3179044 Maybridge4_001646 CN(C1CCCCC1)C(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K19 compound treatment 0.221 0.00578 0.08 0.191 -0.0257 -0.43 -0.246 -0.5611 3179045 Maybridge4_001647 COc1ccc(Cc2nnc(SCC(=O)C(C)(C)C)n2c3ccc(F)cc3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K20 compound treatment 0.206 -0.00922 -0.13 0.232 0.0153 0.26 0.0889 0.3071 3063747 Maybridge4_001648 COc1cccc(NC(=O)NCCN2CCN=C2C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K21 compound treatment 0.223 0.00778 0.11 0.278 0.0613 1.03 0.8067 0.779 1463967 Maybridge4_001649 Cc1ccc(cc1)C(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K22 compound treatment 0.215 -2.19E-4 0.0 0.214 -0.00266 -0.04 -0.0337 -0.7549 1183986 Maybridge4_001650 O=C(Nc1cccs1)Nc2nnc(s2)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K23 mock treatment 0.227 0.0118 0.17 0.238 0.0213 0.36 0.3725 0.9408 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 K24 mock treatment 0.2 -0.0152 -0.22 0.222 0.00534 0.09 -0.0905 -0.3844 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L01 compound treatment 0.19 -0.0252 -0.36 0.293 0.0763 1.28 0.651 0.489 3179046 Maybridge4_001651 CC(C)c1ccc(NC(=O)CSc2nnc(O)n2C3CC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L02 compound treatment 0.174 -0.0412 -0.59 0.115 -0.102 -1.71 -1.6234 -0.8993 3063748 Maybridge4_001652 CC(C)(CC(=O)Nc1ccc(F)cc1)Sc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L03 compound treatment 0.243 0.0278 0.4 0.256 0.0393 0.66 0.7479 0.9705 1296513 Maybridge4_001653 Cc1ccccc1NC(=O)Nc2ccccc2N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L04 compound treatment 0.235 0.0198 0.28 0.268 0.0513 0.86 0.8094 0.8924 3179047 Maybridge4_001654 O=c1[nH]cc(N2CCN(Cc3ccccc3)CC2)c(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L05 compound treatment 0.205 -0.0102 -0.15 0.191 -0.0257 -0.43 -0.4078 -0.8969 1703134 Maybridge4_001655 CC(C)(C)c1ccc(Oc2ccc(NC(=O)c3ccccc3)cn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L06 compound treatment 0.232 0.0168 0.24 0.297 0.0803 1.35 1.1233 0.8201 3179048 Maybridge4_001656 Cc1nc2n(CC=C)c(=S)sc2c(=O)n1/N=C/c3ccc(Cl)cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L07 compound treatment 0.272 0.0568 0.81 0.271 0.0543 0.91 1.2193 0.9983 3063749 Maybridge4_001657 CN(C)C(=O)Oc1nnc(SCC(=O)c2ccc3OCCOc3c2)n1C4Cc5ccccc5C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L08 compound treatment 0.247 0.0318 0.45 0.252 0.0353 0.59 0.7409 0.9914 1284108 Maybridge4_001658 C1CCc2c(C1)sc3ncnc(Oc4ccccc4)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L09 compound treatment 0.222 0.00678 0.1 0.215 -0.00166 -0.03 0.0489 0.4849 1451783 Maybridge4_001659 Cc1ccc2cc(OC(=O)c3ccc(Oc4cc(Cl)cc(Cl)c4)o3)ccc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L10 compound treatment 0.249 0.0338 0.48 0.287 0.0703 1.18 1.1765 0.9223 3063750 Maybridge4_001660 C=CCNC(=S)Nc1sc2CCCCc2c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L11 compound treatment 0.224 0.00878 0.13 0.272 0.0553 0.93 0.7456 0.7955 1501773 Maybridge4_001661 CC(C)N(Cc1ccccc1)C(=O)Nc2c(C)onc2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L12 compound treatment 0.248 0.0328 0.47 0.285 0.0683 1.15 1.1427 0.9221 3063751 Maybridge4_001662 Clc1ccc(cc1)C2CCC(CC2)C(=O)NCc3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L13 compound treatment 0.238 0.0228 0.33 0.279 0.0623 1.05 0.9703 0.8854 3179049 Maybridge4_001663 Cc1nc2n(CC=C)c(=S)sc2c(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L14 compound treatment 0.27 0.0548 0.78 0.261 0.0443 0.74 1.0803 0.9997 3063752 Maybridge4_001664 COC(=O)c1cccc(NC(=O)C2=NNC(=O)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L15 compound treatment 0.206 -0.00922 -0.13 0.221 0.00434 0.07 -0.0417 -0.2767 1342676 Maybridge4_001665 Cc1noc(C)c1c2nc(CSc3nnc(O)n3C4CC4)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L16 compound treatment 0.274 0.0588 0.84 0.28 0.0633 1.06 1.3463 0.9932 3179050 Maybridge4_001666 FC(F)(F)c1ccnc(SCn2c(=S)sc3ccccc23)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L17 compound treatment 0.223 0.00778 0.11 0.249 0.0323 0.54 0.4626 0.8347 3063753 Maybridge4_001667 Cc1ccnc(SCn2c(=S)sc3ccccc23)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L18 compound treatment 0.256 0.0408 0.58 0.248 0.0313 0.53 0.7845 0.9987 3179051 Maybridge4_001668 CCOC(=O)C1=NN(C(=C2C(=O)c3ccccc3C2=O)S1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L19 compound treatment 0.208 -0.00722 -0.1 0.266 0.0493 0.83 0.5126 0.6142 3063754 Maybridge4_001669 Cc1ccc(Oc2ncccc2NC(=O)c3ccc4OCCCOc4c3)c5CCCc51 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L20 compound treatment 0.312 0.0968 1.38 0.237 0.0203 0.34 1.2203 0.8559 3179052 Maybridge4_001670 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccc(C)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L21 compound treatment 0.269 0.0538 0.77 0.285 0.0683 1.15 1.3551 0.9811 3179053 Maybridge4_001671 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCC(=O)Nc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L22 compound treatment 0.279 0.0638 0.91 0.333 0.116 1.95 2.0259 0.9399 3063755 Maybridge4_001672 Fc1ccc(cc1)S(=O)(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L23 mock treatment 0.26 0.0448 0.64 0.252 0.0353 0.59 0.8724 0.9993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 L24 mock treatment 0.2 -0.0152 -0.22 0.19 -0.0267 -0.45 -0.4703 -0.9452 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M01 compound treatment 0.25 0.0348 0.5 0.279 0.0623 1.05 1.0917 0.9422 1161393 Maybridge4_001673 Cc1c(cnc2cc3OCOc3cc12)c4nnnn4c5ccc(F)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M02 compound treatment 0.222 0.00678 0.1 0.243 0.0263 0.44 0.3812 0.8422 3063756 Maybridge4_001674 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCN(CC3)c4ncccc4C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M03 compound treatment 0.247 0.0318 0.45 0.248 0.0313 0.53 0.6934 0.9974 1702105 Maybridge4_001675 Fc1ccccc1NC(=O)NC2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M04 compound treatment 0.27 0.0548 0.78 0.285 0.0683 1.15 1.3652 0.9827 1481828 Maybridge4_001676 OC(=O)c1ccc2nc3ccsc3c(=O)n2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M05 compound treatment 0.275 0.0598 0.86 0.283 0.0663 1.11 1.392 0.9915 3063779 Maybridge4_001677 FC(F)(F)c1ccc(nc1)N2CCN(Cc3c[nH]nc3c4ccccc4)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M06 compound treatment 0.244 0.0288 0.41 0.304 0.0873 1.47 1.3277 0.8719 3063780 Maybridge4_001678 O=S(=O)(N1CCC2(CC1)OCCO2)c3ccc(s3)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M07 compound treatment 0.291 0.0758 1.08 0.287 0.0703 1.18 1.6013 0.9991 3063781 Maybridge4_001679 Cc1c(cnn1c2ccc(F)cc2)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M08 compound treatment 0.245 0.0298 0.43 0.274 0.0573 0.96 0.9818 0.9328 1213448 Maybridge4_001680 O=C(Nc1csc2ccccc12)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M09 compound treatment 0.278 0.0628 0.9 0.248 0.0313 0.53 1.007 0.9675 1543617 Maybridge4_001681 COc1cc2CCN(C(C)c2cc1OC)S(=O)(=O)c3ccc(s3)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M10 compound treatment 0.237 0.0218 0.31 0.237 0.0203 0.34 0.4617 0.999 1698439 Maybridge4_001682 Fc1ccc(cc1)C(=O)COc2ncnc3cc(Cl)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M11 compound treatment 0.265 0.0498 0.71 0.237 0.0203 0.34 0.7449 0.9433 1129209 Maybridge4_001683 CC(C)(C)c1ccc(NC(=O)Nc2ccc3OCCOc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M12 compound treatment 0.273 0.0578 0.83 0.274 0.0573 0.96 1.265 0.9971 1441238 Maybridge4_001684 CC(=O)N(C(=O)C)n1c(C)nc2c(sc3nnc(c4ccccc4)c(c5ccccc5)c32)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M13 compound treatment 0.283 0.0678 0.97 0.229 0.0123 0.21 0.8321 0.8393 1158309 Maybridge4_001685 O=C(Nc1ccccc1)Oc2ccccc2N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M14 compound treatment 0.282 0.0668 0.96 0.258 0.0413 0.69 1.1661 0.9877 1618806 Maybridge4_001686 C(N(Cc1ccccc1)c2c3CCCc3nc4ncnn24)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M15 compound treatment 0.277 0.0618 0.88 0.249 0.0323 0.54 1.0087 0.9726 1328356 Maybridge4_001687 Clc1ccc(cc1)C(=O)Nc2ccc3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M16 compound treatment 0.24 0.0248 0.35 0.23 0.0133 0.22 0.409 0.9755 1356245 Maybridge4_001688 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCC(Cc4ccccc4)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M17 compound treatment 0.245 0.0298 0.43 0.255 0.0383 0.64 0.7563 0.9799 3063782 Maybridge4_001689 Clc1ccc(Sc2ncccc2C(=O)Oc3ccccc3N4CCOCC4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M18 compound treatment 0.272 0.0568 0.81 0.272 0.0553 0.93 1.2311 0.9978 1407054 Maybridge4_001690 CN(C1CCCCC1)S(=O)(=O)c2ccc(s2)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M19 compound treatment 0.267 0.0518 0.74 0.232 0.0153 0.26 0.7058 0.9001 1657796 Maybridge4_001691 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M20 compound treatment 0.235 0.0198 0.28 0.205 -0.0117 -0.2 0.0617 0.1795 3179139 Maybridge4_001692 CC1=NCCN1CCNC(=O)Nc2ccc(cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M21 compound treatment 0.254 0.0388 0.55 0.286 0.0693 1.16 1.2152 0.9425 1606643 Maybridge4_001693 O=C1N(CCCN2CCOCC2)C(Nc3ccccc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M22 compound treatment 0.235 0.0198 0.28 0.263 0.0463 0.78 0.7501 0.9062 1220768 Maybridge4_001694 OC(=O)COCC(=O)Nc1nnc(s1)C2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M23 mock treatment 0.28 0.0648 0.93 0.224 0.00734 0.12 0.7424 0.7942 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 M24 mock treatment 0.229 0.0138 0.2 0.233 0.0163 0.27 0.3334 0.9869 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N01 compound treatment 0.254 0.0388 0.55 0.201 -0.0157 -0.26 0.2064 0.3363 1585891 Maybridge4_001695 CCc1cccc(C)c1NC(=O)N(Cc2ccccc2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N02 compound treatment 0.251 0.0358 0.51 0.232 0.0153 0.26 0.544 0.9495 3063783 Maybridge4_001696 CC1CC(=O)Nc2ccccc2N1S(=O)(=O)c3ccc(s3)c4cc(on4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N03 compound treatment 0.155 -0.0602 -0.86 0.217 3.44E-4 0.01 -0.605 -0.7024 1262463 Maybridge4_001697 O=C(Nc1cccs1)Nc2ccccc2N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N04 compound treatment 0.234 0.0188 0.27 0.305 0.0883 1.48 1.2384 0.8218 3179140 Maybridge4_001698 Fc1cn(CC2CC(=NO2)c3ccccc3)c(=O)n(CC4CC(=NO4)c5ccccc5)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N05 compound treatment 0.188 -0.0272 -0.39 0.126 -0.0907 -1.52 -1.3512 -0.8603 1190724 Maybridge4_001699 CC(C)(C)c1ccc(Oc2ccc(NC(=O)Nc3cccs3)cn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N06 compound treatment 0.239 0.0238 0.34 0.295 0.0783 1.31 1.1703 0.8617 3179141 Maybridge4_001700 COc1cc(/C=N/n2cnc3n(C)c(=S)sc3c2=O)ccc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N07 compound treatment 0.24 0.0248 0.35 0.323 0.106 1.78 1.5127 0.8313 3063784 Maybridge4_001701 CN(C)C(=O)Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N08 compound treatment 0.296 0.0808 1.16 0.302 0.0853 1.43 1.8299 0.9943 3179142 Maybridge4_001702 CCOC(=O)c1c(SC)n(c2ccccc2)c(=S)n(c3ccccc3)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N09 compound treatment 0.242 0.0268 0.38 0.257 0.0403 0.68 0.7497 0.9636 1226040 Maybridge4_001703 CC(=O)N1CCN(CC1)c2ccc(OC(=O)c3ccc(Oc4cc(Cl)cc(Cl)c4)o3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N10 compound treatment 0.227 0.0118 0.17 0.265 0.0483 0.81 0.6929 0.8361 3063785 Maybridge4_001704 CN(C)/C=N\c1cc(C)c(C#N)c2nc3ccccc3n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N11 compound treatment 0.267 0.0518 0.74 0.32 0.103 1.73 1.7502 0.928 1109792 Maybridge4_001705 OC(CN1CCOCC1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N12 compound treatment 0.216 7.81E-4 0.01 0.329 0.112 1.89 1.3412 0.7113 3179143 Maybridge4_001706 O=C(Cn1cc(nc1SCc2ccccc2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N13 compound treatment 0.178 -0.0372 -0.53 0.235 0.0183 0.31 -0.1587 -0.2581 1537386 Maybridge4_001707 C=CCn1c(Sc2ncnc3n(ncc23)c4ccccc4)nnc1c5ccncc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N14 compound treatment 0.242 0.0268 0.38 0.296 0.0793 1.33 1.2125 0.875 3063786 Maybridge4_001708 Fc1cc(F)cc(NC(=O)C2=NNC(=O)CC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N15 compound treatment 0.283 0.0678 0.97 0.26 0.0433 0.73 1.2 0.99 1514475 Maybridge4_001709 CN(CCc1ccccn1)C(=O)c2c(C)onc2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N16 compound treatment 0.301 0.0858 1.23 0.268 0.0513 0.86 1.477 0.9851 1207655 Maybridge4_001710 CCOc1ncc(c2nnnn2c3ccc(C)cc3)c(n1)c4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N17 compound treatment 0.313 0.0978 1.4 0.3 0.0833 1.4 1.9781 1.0 3179144 Maybridge4_001711 COc1ccc(cc1)C(=O)CSc2nnc(O)n2Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N18 compound treatment 0.257 0.0418 0.6 0.277 0.0603 1.01 1.1388 0.9683 3063787 Maybridge4_001712 CC1CN(CC(C)O1)c2ccc3nnc(c4ccc(cc4)C(F)(F)F)n3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N19 compound treatment 0.298 0.0828 1.18 0.282 0.0653 1.1 1.6128 0.9993 3179145 Maybridge4_001713 FC(F)(F)c1ccc(cc1)C(=O)n2ccc(n2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N20 compound treatment 0.239 0.0238 0.34 0.283 0.0663 1.11 1.0279 0.8828 3179146 Maybridge4_001714 CCCc1c(cnn1c2ccccc2)C(=O)NC3CCN(CC3)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N21 compound treatment 0.267 0.0518 0.74 0.278 0.0613 1.03 1.2518 0.9869 3063788 Maybridge4_001715 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCc3nc4ccccc4s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N22 compound treatment 0.267 0.0518 0.74 0.258 0.0413 0.69 1.0144 0.9995 3179147 Maybridge4_001716 O=C(Nc1ccccc1)N2CCN(CC2)c3ncccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N23 mock treatment 0.257 0.0418 0.6 0.245 0.0283 0.48 0.759 0.9936 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 N24 mock treatment 0.207 -0.00822 -0.12 0.204 -0.0127 -0.21 -0.2333 -0.9611 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O01 compound treatment 0.232 0.0168 0.24 0.249 0.0323 0.54 0.5536 0.9327 3063789 Maybridge4_001717 NC(=O)C1CCN(CC(O)(c2ccccc2)c3ccccc3)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O02 compound treatment 0.245 0.0298 0.43 0.221 0.00434 0.07 0.3528 0.8163 1354647 Maybridge4_001718 O=C1N(Cc2ccccc2)Cc3c1[nH]c4cc(nn4c3=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O03 compound treatment 0.24 0.0248 0.35 0.253 0.0363 0.61 0.682 0.9666 1618786 Maybridge4_001719 O=C(NC1CCCc2ccccc12)Nc3ccc(OCc4ccccc4)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O04 compound treatment 0.219 0.00378 0.05 0.267 0.0503 0.84 0.6357 0.7508 1669773 Maybridge4_001720 NC(=O)c1ccc2nc3ccsc3c(=O)n2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O05 compound treatment 0.264 0.0488 0.7 0.233 0.0163 0.27 0.6874 0.9168 1411321 Maybridge4_001721 COc1ccc(cc1)c2n[nH]cc2CN3CCC(CC3)c4ccccc4OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O06 compound treatment 0.27 0.0548 0.78 0.254 0.0373 0.63 0.9973 0.9939 1472712 Maybridge4_001722 Cc1cc(=O)oc2cc(NC(=O)CC(CC(=O)O)c3ccccc3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O07 compound treatment 0.238 0.0228 0.33 0.323 0.106 1.78 1.4925 0.8226 1310764 Maybridge4_001723 Fc1ccc(cc1)N2CCN(CC2)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O08 compound treatment 0.199 -0.0162 -0.23 0.2 -0.0167 -0.28 -0.3617 -0.9957 1239250 Maybridge4_001724 O=C(Nc1csc2ccccc12)N3CCN(CC3)C(c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O09 compound treatment 0.229 0.0138 0.2 0.234 0.0173 0.29 0.3452 0.982 1699746 Maybridge4_001725 COc1cc2CCN(C(C)c2cc1OC)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O10 compound treatment 0.265 0.0498 0.71 0.255 0.0383 0.64 0.9586 0.9987 1354931 Maybridge4_001726 Cc1cc(no1)c2nc(CCn3c(=O)oc4ccc(C)cc34)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O11 compound treatment 0.16 -0.0552 -0.79 0.226 0.00934 0.16 -0.4476 -0.5559 1136980 Maybridge4_001727 O=C(Nc1cccs1)Nc2ccc3OCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O12 compound treatment 0.272 0.0568 0.81 0.231 0.0143 0.24 0.7445 0.8789 3179148 Maybridge4_001728 Clc1ccc(CS/C(=N\c2ccccc2)/C(C#N)c3nc4ccccc4[nH]3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O13 compound treatment 0.237 0.0218 0.31 0.257 0.0403 0.68 0.6991 0.9379 1462458 Maybridge4_001729 Clc1ccsc1C(=O)Oc2ccccc2N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O14 compound treatment 0.052 -0.163 -2.33 0.05 -0.167 -2.8 -3.6287 -0.996 3179149 Maybridge4_001730 Cn1c(Sc2c3CCCc3nc4ncnn24)nnc1c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O15 compound treatment 0.224 0.00878 0.13 0.247 0.0303 0.51 0.4489 0.8559 1250957 Maybridge4_001731 Cn1nccc1NC(=O)COCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O16 compound treatment 0.251 0.0358 0.51 0.223 0.00634 0.11 0.4372 0.8363 1424513 Maybridge4_001732 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3cc4c(C)cc(C)cc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O17 compound treatment 0.262 0.0468 0.67 0.31 0.0933 1.57 1.581 0.928 3063791 Maybridge4_001733 Cc1c(CN2CCN(CC2)c3ccccn3)sc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O18 compound treatment 0.225 0.00978 0.14 0.235 0.0183 0.31 0.3166 0.9363 1224470 Maybridge4_001734 CN(CCc1ccccn1)C(=O)c2cccnc2Oc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O19 compound treatment 0.181 -0.0342 -0.49 0.187 -0.0297 -0.5 -0.6981 -1.0 1228387 Maybridge4_001735 O=S(=O)(Nc1ccccc1Oc2ccccc2)c3ccc(s3)c4ccon4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O20 compound treatment 0.23 0.0148 0.21 0.204 -0.0127 -0.21 -7.0E-4 -0.0024 3179150 Maybridge4_001736 CC1=NCCN1CCNC(=O)Nc2cc(C)cc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O21 compound treatment 0.199 -0.0162 -0.23 0.227 0.0103 0.17 -0.0413 -0.1425 1638495 Maybridge4_001737 O=C1NCCN1CCN2C(Nc3ccccc3C2=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O22 compound treatment 0.191 -0.0242 -0.35 0.253 0.0363 0.61 0.1864 0.2657 3063793 Maybridge4_001738 Cc1nn(nc1c2nnc(o2)c3cccc4ccccc34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O23 mock treatment 0.221 0.00578 0.08 0.177 -0.0397 -0.67 -0.4122 -0.6145 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 O24 mock treatment 0.231 0.0158 0.23 0.24 0.0233 0.39 0.4367 0.9657 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P01 compound treatment 0.229 0.0138 0.2 0.264 0.0473 0.79 0.7013 0.8566 1685839 Maybridge4_001739 CN(C1CCCCC1)C(=O)NS(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P02 compound treatment 0.222 0.00678 0.1 0.304 0.0873 1.47 1.1052 0.7522 3063794 Maybridge4_001740 CC(C)c1ccc(NC(=O)C2=NNC(=O)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P03 compound treatment 0.204 -0.0112 -0.16 0.221 0.00434 0.07 -0.0619 -0.3513 1248453 Maybridge4_001741 Oc1cc2c(coc2c3ccccc13)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P04 compound treatment 0.23 0.0148 0.21 0.237 0.0203 0.34 0.3909 0.9734 1427084 Maybridge4_001742 S=C(Nc1ccccc1)N2CCCCC2c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P05 compound treatment 0.227 0.0118 0.17 0.25 0.0333 0.56 0.5149 0.881 1556607 Maybridge4_001743 CC(C)(C)c1ccc(Oc2ccc(NC(=O)CC(C)(C)CC(=O)O)cn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P06 compound treatment 0.218 0.00278 0.04 0.315 0.0983 1.65 1.1953 0.7239 1313218 Maybridge4_001744 N#Cc1c2CCCc2c(N3CCCCC3)n4c5ccccc5nc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P07 compound treatment 0.223 0.00778 0.11 0.245 0.0283 0.48 0.4151 0.8496 3063820 Maybridge4_001745 O=C(CSc1nnc(OC(=O)c2cccs2)n1C3CC3)c4ccc5OCCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P08 compound treatment 0.235 0.0198 0.28 0.225 0.00834 0.14 0.2991 0.9474 3063821 Maybridge4_001746 Cc1nn(cc1C2C=C(N=C3SCC(=O)N23)c4ccc(Cl)cc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P09 compound treatment 0.244 0.0288 0.41 0.284 0.0673 1.13 1.0903 0.9064 3063822 Maybridge4_001747 Cc1nc(cn1C)S(=O)(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P10 compound treatment 0.231 0.0158 0.23 0.302 0.0853 1.43 1.1725 0.8086 3063823 Maybridge4_001748 O=C1N(Cc2ccc3nonc3c2)S(=O)(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P11 compound treatment 0.213 -0.00222 -0.03 0.316 0.0993 1.67 1.1566 0.6935 1323976 Maybridge4_001749 Fc1ccc(cc1)C(=O)Nc2ccc3[nH]ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P12 compound treatment 0.23 0.0148 0.21 0.228 0.0113 0.19 0.2841 0.9986 3179235 Maybridge4_001750 Cc1ccccc1C(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P13 compound treatment 0.274 0.0588 0.84 0.262 0.0453 0.76 1.1327 0.9988 1141633 Maybridge4_001751 Cc1cc(NC(=O)Nc2ccccc2)n(n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P14 compound treatment 0.206 -0.00922 -0.13 0.204 -0.0127 -0.21 -0.2434 -0.9737 3179236 Maybridge4_001752 Cc1c(/C=N/N2C(=O)CNC2=S)c(=O)n3c4ccccc4[nH]c3c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P15 compound treatment 0.2 -0.0152 -0.22 0.324 0.107 1.8 1.12 0.6172 3063825 Maybridge4_001753 O=C(NCCc1cccs1)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P16 compound treatment 0.197 -0.0182 -0.26 0.255 0.0383 0.64 0.2708 0.39 3179237 Maybridge4_001754 O=C(Nc1ccc2OCCOc2c1)C3Cc4ccccc4N3C(=O)OCc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P17 compound treatment 0.249 0.0338 0.48 0.25 0.0333 0.56 0.7374 0.9973 3179238 Maybridge4_001755 Cc1noc(C)c1CSc2nnc(O)n2Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P18 compound treatment 0.232 0.0168 0.24 0.217 3.44E-4 0.01 0.1738 0.7239 3063826 Maybridge4_001756 NNC(=O)C1N(N=C(C=C1C(=O)NN)C(=O)c2cccs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P19 compound treatment 0.266 0.0508 0.73 0.29 0.0733 1.23 1.3841 0.9683 3179239 Maybridge4_001757 Cc1cc(C(=O)n2ccc(n2)c3cccs3)c(C)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P20 compound treatment 0.201 -0.0142 -0.2 0.237 0.0203 0.34 0.0976 0.2457 1543173 Maybridge4_001758 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(C)on2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P21 compound treatment 0.224 0.00878 0.13 0.24 0.0233 0.39 0.3659 0.8892 3179240 Maybridge4_001759 COc1ccc(NC(=O)COCC(=O)O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P22 compound treatment 0.234 0.0188 0.27 0.282 0.0653 1.1 0.9655 0.855 3179241 Maybridge4_001760 Cc1onc(c1C(=O)NCC2COc3ccccc3O2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P23 mock treatment 0.249 0.0338 0.48 0.201 -0.0157 -0.26 0.1559 0.2834 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2053 P24 mock treatment 0.218 0.00278 0.04 0.183 -0.0337 -0.56 -0.3713 -0.6557 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A01 compound treatment 0.318 0.0415 0.59 0.244 0.00103 0.02 0.4321 0.7274 3063827 Maybridge4_001761 Cc1noc(C)c1S(=O)(=O)NCC2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A02 compound treatment 0.262 -0.0145 -0.21 0.241 -0.00197 -0.03 -0.1699 -0.8097 3179242 Maybridge4_001762 COc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A03 compound treatment 0.297 0.0205 0.29 0.224 -0.019 -0.32 -0.0176 -0.0407 3063828 Maybridge4_001763 COc1ccc(cc1)c2nnsc2N3C(=O)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A04 compound treatment 0.25 -0.0265 -0.38 0.214 -0.029 -0.49 -0.6117 -0.9924 3179243 Maybridge4_001764 CCn1c(Cn2nnc3ccccc23)nnc1SCC(=O)c4ccc(Br)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A05 compound treatment 0.284 0.00752 0.11 0.229 -0.014 -0.23 -0.0898 -0.348 3179244 Maybridge4_001765 C1Cc2cc(ccc2O1)C3Nc4ccccc4-c5cccn35 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A06 compound treatment 0.309 0.0325 0.47 0.276 0.033 0.55 0.7209 0.9962 3063829 Maybridge4_001766 S=C(Nc1ccccc1)N2c3ccccc3Sc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A07 compound treatment 0.331 0.0545 0.78 0.234 -0.00897 -0.15 0.4449 0.5603 3179245 Maybridge4_001767 O=S(=O)(NCc1ccco1)c2ccc(Oc3c(C#N)cccc3C#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A08 compound treatment 0.301 0.0245 0.35 0.24 -0.00297 -0.05 0.2127 0.6006 3063830 Maybridge4_001768 Nc1nc(Sc2nnc(c3ccncc3)n2c4ccccc4)ncc1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A09 compound treatment 0.277 5.16E-4 0.01 0.261 0.018 0.3 0.2192 0.7241 3179246 Maybridge4_001769 Clc1ccc(COC(=O)c2ccc3ccccc3n2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A10 compound treatment 0.275 -0.00148 -0.02 0.242 -9.69E-4 -0.02 -0.0265 -0.9913 3063831 Maybridge4_001770 O=C(CSc1nnc(o1)c2ccncc2)NC(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A11 compound treatment 0.212 -0.0645 -0.92 0.199 -0.044 -0.74 -1.174 -0.9939 1526124 Maybridge4_001771 S=c1[nH]nc(c2ccncc2)n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A12 compound treatment 0.268 -0.00848 -0.12 0.255 0.012 0.2 0.057 0.2419 3179247 Maybridge4_001772 S=c1[nH]c(=S)c2cnc(nc2[nH]1)N3CCc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A13 compound treatment 0.26 -0.0165 -0.24 0.238 -0.00497 -0.08 -0.2257 -0.9024 3063832 Maybridge4_001773 Cc1cc(C)c2c(n1)sc3c(=O)n(/N=C/c4ccccc4)cnc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A14 compound treatment 0.262 -0.0145 -0.21 0.219 -0.024 -0.4 -0.431 -0.9524 3179248 Maybridge4_001774 Fc1ccc(Cn2nc3sc4ccccc4n3c(=O)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A15 compound treatment 0.237 -0.0395 -0.56 0.248 0.00503 0.08 -0.3396 -0.5948 3063833 Maybridge4_001775 Clc1ccccc1Cn2nnc3c(=S)[nH]cnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A16 compound treatment 0.215 -0.0615 -0.88 0.209 -0.034 -0.57 -1.025 -0.978 3179249 Maybridge4_001776 CCOC(=O)c1c(C)c(C)sc1NC(=S)Nc2cc(C)nn2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A17 compound treatment 0.26 -0.0165 -0.24 0.25 0.00703 0.12 -0.0833 -0.3158 3063834 Maybridge4_001777 CCOC(=O)c1nnn2c1nc(N(CC)CC)c3ccccc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A18 compound treatment 0.302 0.0255 0.36 0.225 -0.018 -0.3 0.0448 0.0947 3179250 Maybridge4_001778 Cc1cc(C)c2c(n1)sc3c(=O)n(NC(=O)Nc4ccccc4)c(C)nc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A19 compound treatment 0.277 5.16E-4 0.01 0.216 -0.027 -0.45 -0.3148 -0.6955 3063835 Maybridge4_001779 CCOC(=O)c1nn(c2ccccc2)c3nc(=O)c(C#N)c(c4ccccc4)n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A20 compound treatment 0.229 -0.0475 -0.68 0.198 -0.045 -0.75 -1.014 -0.9986 3179251 Maybridge4_001780 O=C(Cn1c(=O)n(c2ccccc2)c(=O)c3cc(sc13)c4ccccc4)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A21 compound treatment 0.261 -0.0155 -0.22 0.22 -0.023 -0.39 -0.4292 -0.9654 3179252 Maybridge4_001781 COc1ccc(cc1)n2ncc(NC(=O)NCc3ccccn3)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A22 compound treatment 0.277 5.16E-4 0.01 0.216 -0.027 -0.45 -0.3148 -0.6955 3063836 Maybridge4_001782 COc1ccc(/C=C/2\N=C(N(/N=C/c3cccnc3)C2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A23 mock treatment 0.216 -0.0605 -0.87 0.228 -0.015 -0.25 -0.7894 -0.8762 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 A24 mock treatment 0.301 0.0245 0.35 0.189 -0.054 -0.91 -0.3925 -0.4041 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B01 compound treatment 0.287 0.0105 0.15 0.261 0.018 0.3 0.3204 0.9479 3179253 Maybridge4_001783 OC(=O)CSc1nnc([nH]1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B02 compound treatment 0.271 -0.00548 -0.08 0.284 0.041 0.69 0.4315 0.6225 3063837 Maybridge4_001784 O=c1oc2=C(c3ccccc3)S(=O)(=O)C(=c2o1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B03 compound treatment 0.338 0.0615 0.88 0.24 -0.00297 -0.05 0.587 0.666 3179254 Maybridge4_001785 Cc1cc(C)c2c3NC(=O)CN(C(=O)c3sc2n1)c4ccccc4C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B04 compound treatment 0.291 0.0145 0.21 0.278 0.035 0.59 0.5626 0.9022 1701942 Maybridge4_001786 COc1ccc(cc1)N2C(=O)Cc3ccc(OC)cc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B05 compound treatment 0.374 0.0975 1.39 0.25 0.00703 0.12 1.0697 0.7642 3179255 Maybridge4_001787 Clc1ccc(cc1)n2c(=N)c3cnc(nc3[nH]c2=O)N4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B06 compound treatment 0.358 0.0815 1.17 0.245 0.00203 0.03 0.8486 0.7275 1588538 Maybridge4_001788 Cc1oc2cc(O)ccc2c(=O)c1Oc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B07 compound treatment 0.354 0.0775 1.11 0.288 0.045 0.76 1.3185 0.9826 3179256 Maybridge4_001789 COc1ccc(cc1)n/2c(cs\c2=N/Cc3cccnc3)c4cccc(OC)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B08 compound treatment 0.397 0.121 1.72 0.235 -0.00797 -0.13 1.1244 0.6503 3179257 Maybridge4_001790 O=C(c1ccccc1)c2cccc(NC=C3C(=O)NC(=O)NC3=O)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B09 compound treatment 0.203 -0.0735 -1.05 0.139 -0.104 -1.75 -1.9771 -0.9706 1289329 Maybridge4_001791 O=C1C(=C(c2ccccc2)S(=O)(=O)c3ccccc13)Cc4ccc(cc4)c5nnn[nH]5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B10 compound treatment 0.37 0.0935 1.34 0.237 -0.00597 -0.1 0.875 0.6523 1270319 Maybridge4_001792 O=C(c1ccccn1)c2ccc3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B11 compound treatment 0.366 0.0895 1.28 0.247 0.00403 0.07 0.9532 0.7434 1356935 Maybridge4_001793 C1C2CC3CC1CC(C2)(C3)c4cn5ccccc5n4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B12 compound treatment 0.307 0.0305 0.44 0.24 -0.00297 -0.05 0.2734 0.6223 1489551 Maybridge4_001794 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B13 compound treatment 0.298 0.0215 0.31 0.214 -0.029 -0.49 -0.1262 -0.2193 3063861 Maybridge4_001795 CC(=O)O[C@@H]1[C@H]2CO[C@H](O2)[C@H](OC(=O)C)[C@H]1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B14 compound treatment 0.342 0.0655 0.94 0.248 0.00503 0.08 0.7224 0.7677 1649672 Maybridge4_001796 COc1cc(C(=O)CCC(=O)O)c(OC)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B15 compound treatment 0.292 0.0155 0.22 0.254 0.011 0.19 0.2879 0.9959 1471910 Maybridge4_001797 Cc1ccc(NC(=O)N2C(=O)C3(OCCO3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B16 compound treatment 0.32 0.0435 0.62 0.24 -0.00297 -0.05 0.4049 0.6484 1205899 Maybridge4_001798 CCOC(=O)C1=C(C)N(C)C(=O)N(C)C1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B17 compound treatment 0.37 0.0935 1.34 0.228 -0.015 -0.25 0.7682 0.5644 3063863 Maybridge4_001799 CC(=O)Nc1ccc2oc(cc(=O)c2c1)c3ccc(C#N)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B18 compound treatment 0.335 0.0585 0.84 0.228 -0.015 -0.25 0.4142 0.474 3179258 Maybridge4_001800 Cc1c(sc2nc(C)cc(C)c12)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B19 compound treatment 0.316 0.0395 0.57 0.247 0.00403 0.07 0.4475 0.7861 3063864 Maybridge4_001801 CC(O)/C=C\c1cc[n+](C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B20 compound treatment 0.321 0.0445 0.64 0.241 -0.00197 -0.03 0.4269 0.6695 3179259 Maybridge4_001802 O=C(NC(=S)NC1(CC2CC3CC(C2)C1)C3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B21 compound treatment 0.313 0.0365 0.52 0.253 0.01 0.17 0.4884 0.8899 1176828 Maybridge4_001803 COC(=O)C1C(C(C(=O)OC)S(=O)(=O)CS1(=O)=O)c2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B22 compound treatment 0.305 0.0285 0.41 0.23 -0.013 -0.22 0.1345 0.2909 1288189 Maybridge4_001804 COC(=O)C1=C(C)NC(=C(C1)C(=O)OC)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B23 mock treatment 0.321 0.0445 0.64 0.234 -0.00897 -0.15 0.3438 0.5255 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 B24 mock treatment 0.297 0.0205 0.29 0.208 -0.035 -0.59 -0.2075 -0.3162 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C01 compound treatment 0.32 0.0435 0.62 0.307 0.064 1.07 1.2001 0.9663 3179260 Maybridge4_001805 O=S(=O)(NCC1COc2ccccc2O1)c3ccc(s3)S(=O)(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C02 compound treatment 0.265 -0.0115 -0.16 0.244 0.00103 0.02 -0.1039 -0.6291 3063865 Maybridge4_001806 Fc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)c5ccco5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C03 compound treatment 0.432 0.156 2.22 0.283 0.04 0.67 2.048 0.8814 3179353 Maybridge4_001807 COc1ccc(cc1OC)C(=O)NCc2ccc(C#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C04 compound treatment 0.413 0.137 1.95 0.298 0.055 0.92 2.0339 0.9416 3063866 Maybridge4_001808 O=C(Oc1c(c2ccccc2)c(=O)n3CCc4cccc1c43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C05 compound treatment 0.442 0.166 2.37 0.229 -0.014 -0.23 1.5083 0.634 3179354 Maybridge4_001809 FC(F)(F)c1ccc(cc1)c2nnc(SCc3ccncc3)n2Cc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C06 compound treatment 0.319 0.0425 0.61 0.19 -0.053 -0.89 -0.1986 -0.1844 3063867 Maybridge4_001810 CCOC(=O)c1nnn2c1nc(Sc3nc4ccccc4o3)c5ccccc52 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C07 compound treatment 0.544 0.268 3.83 0.309 0.066 1.11 3.4894 0.8759 3179355 Maybridge4_001811 COc1cccc(Cc2nnc(o2)c3c(C)onc3c4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C08 compound treatment 0.117 -0.159 -2.28 0.059 -0.184 -3.09 -3.7964 -0.9889 3179356 Maybridge4_001812 C=CCn1c(=S)sc2c(Sc3nnc(o3)c4ccco4)ncnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C09 compound treatment 0.447 0.171 2.44 0.292 0.049 0.82 2.3065 0.8961 3063868 Maybridge4_001813 Clc1ccc(Cn2c(=O)n(Cc3ccc(Cl)cc3)c4ccccc4c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C10 compound treatment 0.509 0.233 3.33 0.243 3.12E-5 0.0 2.3521 0.7072 3179357 Maybridge4_001814 Nc1nc(SCC(=O)NC(=O)Nc2ccccc2)ncc1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C11 compound treatment 0.456 0.18 2.57 0.224 -0.019 -0.32 1.5905 0.6147 2099392 Maybridge4_001815 Cc1nc2ccc(F)cc2c3N(CCc31)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C12 compound treatment 0.5 0.224 3.2 0.224 -0.019 -0.32 2.0356 0.6336 3179358 Maybridge4_001816 C=CCSc1ncc2c(=S)[nH]c(=S)[nH]c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C13 compound treatment 0.494 0.218 3.11 0.277 0.034 0.57 2.6039 0.8232 3179359 Maybridge4_001817 Cc1cc(C)c2c(n1)sc3c(SCC(=O)c4ccc(Br)cc4)ncnc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C14 compound treatment 0.489 0.213 3.04 0.227 -0.016 -0.27 1.9599 0.6423 3063869 Maybridge4_001818 C=CCn1nc2sc3ccccc3n2c(=O)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C15 compound treatment 0.502 0.226 3.23 0.227 -0.016 -0.27 2.0914 0.6461 3179360 Maybridge4_001819 COc1ccc(Nc2ncnc3n(Cc4ccccc4Cl)nnc23)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C16 compound treatment 0.438 0.162 2.31 0.233 -0.00997 -0.17 1.5153 0.6542 3063871 Maybridge4_001820 CCOC(=O)c1c(C)c(C)sc1NC(=S)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C17 compound treatment 0.462 0.186 2.65 0.307 0.064 1.07 2.6363 0.9208 3179361 Maybridge4_001821 CCOC(=O)c1nnn2c1nc(N3CCN(CC3)c4ccccc4)c5ccccc52 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C18 compound treatment 0.283 0.00652 0.09 0.154 -0.089 -1.49 -0.99 -0.6617 3063872 Maybridge4_001822 Cc1cc(C)c2c(=O)n(sc2n1)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C19 compound treatment 0.486 0.21 3.0 0.27 0.027 0.45 2.4399 0.805 3179362 Maybridge4_001823 COc1ccc(cc1)C2C(=C(N)N3CCc4cc(OC)c(OC)cc4C3=C2C#N)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C20 compound treatment 0.476 0.2 2.85 0.242 -9.69E-4 -0.02 2.0065 0.7031 3063873 Maybridge4_001824 CNC(=O)NC(=O)Cn1cnc2sc(cc2c1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C21 compound treatment 0.49 0.214 3.05 0.266 0.023 0.39 2.4329 0.7903 3179363 Maybridge4_001825 COc1cc2CCN3C(N(N=C3C(=O)c4cccs4)c5ccccc5)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C22 compound treatment 0.461 0.185 2.64 0.247 0.00403 0.07 1.9141 0.725 3063874 Maybridge4_001826 Fc1ccc(/C=N/N2C(=O)/C(=C/c3ccco3)/N=C2c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C23 mock treatment 0.324 0.0475 0.68 0.287 0.044 0.74 1.0032 0.9991 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 C24 mock treatment 0.225 -0.0515 -0.74 0.206 -0.037 -0.62 -0.9595 -0.9964 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D01 compound treatment 0.257 -0.0195 -0.28 0.249 0.00603 0.1 -0.1255 -0.4232 3179364 Maybridge4_001827 CCOC(=O)CSc1nc(Nc2ccc(OC)cc2)c3cnc(nc3n1)N(CC)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D02 compound treatment 0.275 -0.00148 -0.02 0.276 0.033 0.55 0.377 0.6795 1016783 Maybridge4_001828 CSc1ncnc2[nH]cnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D03 compound treatment 0.45 0.174 2.48 0.316 0.073 1.23 2.6217 0.9471 3179365 Maybridge4_001829 CCOC(=O)CSc1nc(Nc2ccccc2)c3cnc(nc3n1)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D04 compound treatment 0.481 0.205 2.93 0.28 0.037 0.62 2.508 0.8386 3063875 Maybridge4_001830 CCn1c(C)[n+](CC)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D05 compound treatment 0.485 0.209 2.98 0.324 0.081 1.36 3.0707 0.9368 3179366 Maybridge4_001831 Nc1c(C#N)c(cc2c3ccccc3oc(=O)c12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D06 compound treatment 0.395 0.119 1.7 0.144 -0.099 -1.66 0.0241 0.0102 1156367 Maybridge4_001832 CC(=O)Oc1ccc2c(=O)c(Oc3ccc(Cl)cc3)c(C)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D07 compound treatment 0.503 0.227 3.24 0.34 0.097 1.63 3.4426 0.9493 3179367 Maybridge4_001833 CC(/C=N/N1C(=O)c2ccccc2C1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D08 compound treatment 0.526 0.25 3.57 0.387 0.144 2.42 4.233 0.982 3063876 Maybridge4_001834 COC(=O)c1sc(=S)sc1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D09 compound treatment 0.54 0.264 3.77 0.38 0.137 2.3 4.2916 0.9719 1027030 Maybridge4_001835 Clc1ccc2OC(CC(=O)c2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D10 compound treatment 0.523 0.247 3.53 0.38 0.137 2.3 4.1196 0.9786 1567173 Maybridge4_001836 C=CCN1C(=O)NC2(CCCCC2)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D11 compound treatment 0.423 0.147 2.1 0.42 0.177 2.97 3.5829 0.9854 1014811 Maybridge4_001837 O=C(N(C(=O)c1ccccc1)C(=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D12 compound treatment 0.488 0.212 3.03 0.384 0.141 2.37 3.8131 0.9926 1422860 Maybridge4_001838 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D13 compound treatment 0.469 0.193 2.75 0.357 0.114 1.91 3.3005 0.9842 3063327 Maybridge4_001839 CCOc1ccc2nc(S/C=C/C(=O)c3ccc(Cl)cc3)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D14 compound treatment 0.49 0.214 3.05 0.375 0.132 2.22 3.7265 0.9876 1403045 Maybridge4_001840 COc1cc(c(OC)cc1C)c2cc(OC)c(C)cc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D15 compound treatment 0.488 0.212 3.03 0.429 0.186 3.12 4.3472 0.9999 1267535 Maybridge4_001841 OC(=O)C(Sc1ccccc1C(=O)O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D16 compound treatment 0.468 0.192 2.74 0.396 0.153 2.57 3.7532 0.9995 3063328 Maybridge4_001842 CC(C)(C)[C@H]1COC(=N1)CC2=N[C@H](CO2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D17 compound treatment 0.536 0.26 3.71 0.429 0.186 3.12 4.8326 0.9963 1035033 Maybridge4_001843 O=C(C1=NNCC1c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D18 compound treatment 0.5 0.224 3.2 0.388 0.145 2.43 3.9819 0.9909 1414609 Maybridge4_001844 CC(=O)Oc1ccc2c(=O)c(c3nc4ccccc4n3C)c(C)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D19 compound treatment 0.468 0.192 2.74 0.406 0.163 2.74 3.8719 1.0 3063329 Maybridge4_001845 CC1=CC(=O)OC(C1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D20 compound treatment 0.491 0.215 3.07 0.351 0.108 1.81 3.4518 0.9685 1054135 Maybridge4_001846 CCc1c(O)nc2ccccn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D21 compound treatment 0.524 0.248 3.54 0.308 0.065 1.09 3.2752 0.884 1416442 Maybridge4_001847 CCN(CC)CCC1S(=O)(=O)CC(CS1(=O)=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D22 compound treatment 0.508 0.232 3.31 0.3 0.057 0.96 3.0185 0.8757 3179368 Maybridge4_001848 C(/N=C/c1cn(nc1c2ccccc2)c3ccccc3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D23 mock treatment 0.348 0.0715 1.02 0.269 0.026 0.44 1.0323 0.928 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 D24 mock treatment 0.23 -0.0465 -0.66 0.209 -0.034 -0.57 -0.8733 -0.9971 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E01 compound treatment 0.256 -0.0205 -0.29 0.269 0.026 0.44 0.1018 0.1934 3063330 Maybridge4_001849 O=C(Nc1cccs1)N2CCN(CC2)C(=O)C3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E02 compound treatment 0.306 0.0295 0.42 0.228 -0.015 -0.25 0.1209 0.2461 3179369 Maybridge4_001850 Clc1ccc(NC(=O)N2N=C3C(CCc4ccccc34)C2c5cccs5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E03 compound treatment 0.414 0.138 1.97 0.212 -0.031 -0.52 1.0233 0.503 3063331 Maybridge4_001851 CC(C)(C)c1cc(C(=O)NCc2ccc(C#N)cc2)n(Cc3ccccc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E04 compound treatment 0.468 0.192 2.74 0.245 0.00203 0.03 1.9611 0.7159 3179370 Maybridge4_001852 C1Cc2ccccc2N1c3nnc(c4ccccc4)c(n3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E05 compound treatment 0.486 0.21 3.0 0.341 0.098 1.65 3.2825 0.9601 3179371 Maybridge4_001853 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)N3CCCN(CC3)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E06 compound treatment 0.475 0.199 2.84 0.35 0.107 1.8 3.2781 0.9756 3063332 Maybridge4_001854 CCOC(=O)c1nnn2c1nc(Sc3nnc(c4ccncc4)n3C)c5ccccc52 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E07 compound treatment 0.526 0.25 3.57 0.374 0.131 2.2 4.0788 0.9729 3179372 Maybridge4_001855 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E08 compound treatment 0.528 0.252 3.6 0.366 0.123 2.06 4.004 0.9653 1566406 Maybridge4_001856 CNc1nc(=S)[nH]c2sc3CCCCc3c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E09 compound treatment 0.575 0.299 4.27 0.353 0.11 1.85 4.3251 0.9297 3179373 Maybridge4_001857 OC[C@@H]1O[C@@H](C[C@H]1O)n2cnc3c(=O)[nH]cnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E10 compound treatment 0.453 0.177 2.52 0.447 0.204 3.42 4.2068 0.9888 3063334 Maybridge4_001858 COc1ccc(Nc2ncc(C#N)c(N)n2)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E11 compound treatment 0.51 0.234 3.34 0.322 0.079 1.33 3.2998 0.9182 3179374 Maybridge4_001859 CCNc1nc(=S)[nH]c2n(ncc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E12 compound treatment 0.499 0.223 3.18 0.32 0.077 1.29 3.1648 0.9212 3063335 Maybridge4_001860 CCN(CC)c1ncc2c(=S)[nH]c(=S)[nH]c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E13 compound treatment 0.495 0.219 3.13 0.371 0.128 2.15 3.7296 0.9833 3179375 Maybridge4_001861 Cc1cc(C)c2c(n1)sc3c(Sc4nnc(o4)c5ccncc5)ncnc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E14 compound treatment 0.491 0.215 3.07 0.329 0.086 1.44 3.1907 0.9409 3179376 Maybridge4_001862 CCOC(=O)N1CCc2c(C1)sc3ncn(Cc4ccc(Cl)cc4)c(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E15 compound treatment 0.432 0.156 2.22 0.405 0.162 2.72 3.4959 0.995 3063336 Maybridge4_001863 Clc1ccccc1C2C3CCc4ccccc4C3=NN2C(=S)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E16 compound treatment 0.508 0.232 3.31 0.413 0.17 2.85 4.3596 0.9973 1616264 Maybridge4_001864 CC1=NN(C(=O)C1)c2ncnc3sc4CCCCc4c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E17 compound treatment 0.496 0.22 3.14 0.392 0.149 2.5 3.989 0.9937 3179377 Maybridge4_001865 CCOC(=O)c1nnn2c1nc(N(Cc3ccccc3)Cc4ccccc4)c5ccccc52 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E18 compound treatment 0.474 0.198 2.83 0.412 0.169 2.84 4.0038 1.0 3063337 Maybridge4_001866 NNC(=O)/C(=C\c1ccccc1)/NC(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E19 compound treatment 0.484 0.208 2.97 0.361 0.118 1.98 3.4997 0.9807 3179378 Maybridge4_001867 Cc1ccc(Cc2nn3c(nn(c4ccc(Cl)cc4)c3nc2=O)C(=O)c5cccs5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E20 compound treatment 0.52 0.244 3.48 0.431 0.188 3.16 4.6945 0.9988 3063338 Maybridge4_001868 Fc1ccc(Cn2nc3CSc4ccccc4-n3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E21 compound treatment 0.501 0.225 3.21 0.33 0.087 1.46 3.3037 0.9364 3063339 Maybridge4_001869 Cc1ccc2nc(C)c3CCN(c3c2c1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E22 compound treatment 0.435 0.159 2.27 0.267 0.024 0.4 1.8885 0.82 3179379 Maybridge4_001870 Fc1ccc(/C=C\2/N=C(N(CC(=O)c3ccco3)C2=O)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E23 mock treatment 0.332 0.0555 0.79 0.272 0.029 0.49 0.906 0.9725 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 E24 mock treatment 0.24 -0.0365 -0.52 0.206 -0.037 -0.62 -0.8078 -0.9963 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F01 compound treatment 0.289 0.0125 0.18 0.254 0.011 0.19 0.2575 0.9999 3179475 Maybridge4_001871 Cc1cc(nc2oc3C(=O)N(CC(=O)Nc3c12)c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F02 compound treatment 0.393 0.117 1.67 0.235 -0.00797 -0.13 1.0839 0.6483 1429948 Maybridge4_001872 CC1(C)C(NC(=O)C2CCCCC2)[C@]3(C)CCC1C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F03 compound treatment 0.52 0.244 3.48 0.253 0.01 0.17 2.582 0.7404 3179476 Maybridge4_001873 CCN(CC)c1ncc2c(NCc3ccccc3)nc(SCc4ccccc4)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F04 compound treatment 0.482 0.206 2.94 0.243 3.12E-5 0.0 2.079 0.7072 1050962 Maybridge4_001874 NC(=O)CCCCC1CCSS1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F05 compound treatment 0.501 0.225 3.21 0.363 0.12 2.01 3.6953 0.9748 3179477 Maybridge4_001875 O=C(CN1CCc2ccccc12)Nc3scc4c3c(=O)oc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F06 compound treatment 0.449 0.173 2.47 0.381 0.138 2.32 3.383 0.9995 3063341 Maybridge4_001876 CC1(C)C2CCC1(C)c3noc(c23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F07 compound treatment 0.589 0.313 4.47 0.403 0.16 2.69 5.0601 0.9703 1040822 Maybridge4_001877 Cc1ccc(NC(=O)N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F08 compound treatment 0.518 0.242 3.45 0.452 0.209 3.51 4.9236 1.0 1502018 Maybridge4_001878 COc1ccc2oc(cc(=O)c2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F09 compound treatment 0.286 0.00952 0.14 0.227 -0.016 -0.27 -0.0933 -0.3103 3063363 Maybridge4_001879 O=C1/C(=C/c2ccc(cc2)c3nnn[nH]3)/C(Oc4ccccc14)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F10 compound treatment 0.505 0.229 3.27 0.477 0.234 3.93 5.0888 0.9958 3063364 Maybridge4_001880 CC1(C)NC(=O)N(CC=C)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F11 compound treatment 0.413 0.137 1.95 0.408 0.165 2.77 3.3394 0.9854 3063365 Maybridge4_001881 Clc1ccccc1CNC(=S)NC2(CC3CC4CC(C3)C2)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F12 compound treatment 0.389 0.113 1.61 0.422 0.179 3.0 3.2628 0.9572 3063366 Maybridge4_001882 Fc1ccc(cc1)N(Cc2ccc(Br)cc2)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F13 compound treatment 0.499 0.223 3.18 0.41 0.167 2.8 4.2329 0.998 1687915 Maybridge4_001883 CC1(C)CC(=O)C=C(C1)Sc2nc3ccccc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F14 compound treatment 0.481 0.205 2.93 0.431 0.188 3.16 4.3001 0.9993 3063367 Maybridge4_001884 C[n+]1ccc(CCc2cc[n+](C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F15 compound treatment 0.47 0.194 2.77 0.348 0.105 1.76 3.2038 0.9763 1612566 Maybridge4_001885 CCC(=O)N1N(C(=O)CC)c2cc(Cl)ccc2-n3c1nn(C(=O)CC)c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F16 compound treatment 0.282 0.00552 0.08 0.125 -0.118 -1.98 -1.3443 -0.6784 1406161 Maybridge4_001886 CC(=O)Oc1c(I)c(=O)n(C)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F17 compound treatment 0.483 0.207 2.95 0.455 0.212 3.56 4.6052 0.9957 3179478 Maybridge4_001887 CCSC(=O)NC1CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F18 compound treatment 0.467 0.191 2.73 0.447 0.204 3.42 4.3484 0.9936 3179479 Maybridge4_001888 C1C(=CC(=NN=C1c2ccccc2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F19 compound treatment 0.385 0.109 1.55 0.407 0.164 2.75 3.0443 0.9632 1002179 Maybridge4_001889 Clc1ccc(cc1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F20 compound treatment 0.384 0.108 1.54 0.264 0.021 0.35 1.337 0.8474 3063368 Maybridge4_001890 CCC(C)Sc1nnc(S)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F21 compound treatment 0.493 0.217 3.1 0.414 0.171 2.87 4.2197 0.9993 3179480 Maybridge4_001891 COC(=O)/C(=C/c1ccccc1)/c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F22 compound treatment 0.456 0.18 2.57 0.264 0.021 0.35 2.0653 0.7968 1172572 Maybridge4_001892 O=c1[nH]cc(NCc2ccccc2)c(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F23 mock treatment 0.349 0.0725 1.04 0.288 0.045 0.76 1.2679 0.9879 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 F24 mock treatment 0.222 -0.0545 -0.78 0.249 0.00603 0.1 -0.4795 -0.6101 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G01 compound treatment 0.215 -0.0615 -0.88 0.244 0.00103 0.02 -0.6096 -0.6931 3179481 Maybridge4_001893 CCOC(=O)N1CCC(CC1)NC(=O)CCCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G02 compound treatment 0.377 0.101 1.44 0.261 0.018 0.3 1.2306 0.8376 3179482 Maybridge4_001894 O=C1CSC2=NC3=C(CCc4ccccc34)C(N12)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G03 compound treatment 0.485 0.209 2.98 0.26 0.017 0.29 2.3111 0.7713 3063369 Maybridge4_001895 CCOC(=O)c1ncn(Cc2ccccc2)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G04 compound treatment 0.47 0.194 2.77 0.242 -9.69E-4 -0.02 1.9458 0.7029 3063370 Maybridge4_001896 S=c1[nH]nc(Cn2nnc3ccccc23)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G05 compound treatment 0.534 0.258 3.68 0.395 0.152 2.55 4.4089 0.9839 3179483 Maybridge4_001897 COc1cccc(Cc2nnc(o2)c3ccc(s3)c4cccs4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G06 compound treatment 0.52 0.244 3.48 0.391 0.148 2.48 4.2198 0.9863 3063371 Maybridge4_001898 Cn1nc2c3ccccc3n(Cc4ccccc4)c2nc1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G07 compound treatment 0.508 0.232 3.31 0.403 0.16 2.69 4.2409 0.9946 3179484 Maybridge4_001899 CCOC(=O)c1cnn(C(=O)Cc2cccc(OC)c2)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G08 compound treatment 0.504 0.228 3.25 0.421 0.178 2.99 4.414 0.9991 1696254 Maybridge4_001900 COc1cc(OC)c2nc(C)c3CCSc3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G09 compound treatment 0.52 0.244 3.48 0.389 0.146 2.45 4.1961 0.9852 3179485 Maybridge4_001901 CC(=O)Nc1ccccc1OCC2CC(=NO2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G10 compound treatment 0.422 0.146 2.08 0.387 0.144 2.42 3.1812 0.9972 3179486 Maybridge4_001902 C1Sc2nnc(c3ccccc3)n2N=C1c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G11 compound treatment 0.453 0.177 2.52 0.458 0.215 3.61 4.3373 0.9847 3063373 Maybridge4_001903 S=c1nc(Nc2ccccc2)c3cnn(c4ccccc4)c3[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G12 compound treatment 0.505 0.229 3.27 0.347 0.104 1.75 3.5459 0.9569 3179487 Maybridge4_001904 CN1CCN(CC1)c2ncc3c(=S)[nH]c(=S)[nH]c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G13 compound treatment 0.482 0.206 2.94 0.425 0.182 3.06 4.239 0.9998 3063374 Maybridge4_001905 CCn1c(Sc2ncnc3c2sc4nc(C)cc(C)c43)nnc1c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G14 compound treatment 0.448 0.172 2.45 0.45 0.207 3.47 4.1918 0.9855 3179488 Maybridge4_001906 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=S)N3CCc4ccccc34)sc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G15 compound treatment 0.511 0.235 3.35 0.407 0.164 2.75 4.3187 0.9952 3179489 Maybridge4_001907 CCNC(=S)N1N=C2C(CCc3ccccc23)C1c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G16 compound treatment 0.423 0.147 2.1 0.439 0.196 3.29 3.8084 0.9763 1303898 Maybridge4_001908 CC1=NN(C(=O)C1)c2nc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G17 compound treatment 0.526 0.25 3.57 0.386 0.143 2.4 4.2212 0.9814 3063375 Maybridge4_001909 CCOC(=O)C1=NN(C2N1CCc3cc(OC)c(OC)cc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G18 compound treatment 0.536 0.26 3.71 0.393 0.15 2.52 4.4054 0.9821 3179490 Maybridge4_001910 COc1cc(/C=C\2/N=C(N(C)C2=O)c3ccccc3)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G19 compound treatment 0.561 0.285 4.07 0.35 0.107 1.8 4.1479 0.9324 3063377 Maybridge4_001911 Cc1c(C)c(=O)n(Cc2ccc(Br)cc2)c(=O)n1Cc3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G20 compound treatment 0.502 0.226 3.23 0.359 0.116 1.95 3.658 0.9708 3179491 Maybridge4_001912 O=C(Cn1nc2CSc3ccccc3-n2c1=O)NC(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G21 compound treatment 0.449 0.173 2.47 0.438 0.195 3.27 4.0595 0.9903 3179492 Maybridge4_001913 CCOC(=O)c1sc2nc(C)cc(C)c2c1NC(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G22 compound treatment 0.443 0.167 2.38 0.252 0.00903 0.15 1.7914 0.7506 1150256 Maybridge4_001914 N(c1ccccc1)c2ncnc3sc(cc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G23 mock treatment 0.302 0.0255 0.36 0.254 0.011 0.19 0.389 0.9505 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 G24 mock treatment 0.195 -0.0815 -1.17 0.23 -0.013 -0.22 -0.9781 -0.8249 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H01 compound treatment 0.271 -0.00548 -0.08 0.284 0.041 0.69 0.4315 0.6225 3179493 Maybridge4_001915 COc1cc(cc(OC)c1OC)c2nnc(SCC(=O)c3ccco3)n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H02 compound treatment 0.364 0.0875 1.25 0.287 0.044 0.74 1.4077 0.9684 1202312 Maybridge4_001916 Clc1ccc(OC2CN(C2)C(=O)N3CC(C3)Oc4ccc(Cl)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H03 compound treatment 0.505 0.229 3.27 0.295 0.052 0.87 2.9288 0.8657 3179494 Maybridge4_001917 O=C(CN1CCc2ccccc12)Nc3nnc(s3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H04 compound treatment 0.542 0.266 3.8 0.34 0.097 1.63 3.8371 0.9286 1178262 Maybridge4_001918 COc1ccc(cc1)c2nc3cc4Nc5ccccc5Oc4cc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H05 compound treatment 0.414 0.138 1.97 0.408 0.165 2.77 3.3495 0.9859 3063402 Maybridge4_001919 O=C(Nc1scc2c1c(=O)oc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H06 compound treatment 0.417 0.141 2.01 0.393 0.15 2.52 3.2018 0.9938 3179495 Maybridge4_001920 FC(F)(F)C(NC(=O)c1cccnc1)(N2CCCC2=O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H07 compound treatment 0.501 0.225 3.21 0.382 0.139 2.33 3.9208 0.9877 1117011 Maybridge4_001921 COc1cccc(NC(=O)N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H08 compound treatment 0.45 0.174 2.48 0.459 0.216 3.63 4.3189 0.9829 3063403 Maybridge4_001922 NC(=O)c1cc(Cl)c(Cl)cc1C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H09 compound treatment 0.637 0.361 5.16 0.548 0.305 5.12 7.2665 1.0 3179496 Maybridge4_001923 O[C@H]1[C@@H](Oc2ccccc2C1=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H10 compound treatment 0.541 0.265 3.78 0.515 0.272 4.57 5.9039 0.9956 3063404 Maybridge4_001924 COc1ncnc(OC)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H11 compound treatment 0.349 0.0725 1.04 0.243 3.12E-5 0.0 0.7338 0.7075 1558852 Maybridge4_001925 CC1=C(C(C2=C(N1)c3ccccc3C2=O)c4ccccc4)C(=O)Nc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H12 compound treatment 0.54 0.264 3.77 0.483 0.24 4.03 5.514 0.9994 1698244 Maybridge4_001926 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H13 compound treatment 0.532 0.256 3.65 0.428 0.185 3.11 4.7803 0.9967 1372400 Maybridge4_001927 O=c1c(c[nH]c2ccccc12)c3nnnn3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H14 compound treatment 0.537 0.261 3.73 0.382 0.139 2.33 4.285 0.9746 3179497 Maybridge4_001928 N1[C@H]([C@H](N=C1c2ccccc2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H15 compound treatment 0.539 0.263 3.75 0.507 0.264 4.43 5.7887 0.9966 3063405 Maybridge4_001929 CO[C@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](O)[C@H](O)[C@H]1OC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H16 compound treatment 0.49 0.214 3.05 0.443 0.2 3.36 4.5335 0.9989 1081881 Maybridge4_001930 COC(=O)CSc1nc2ccccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H17 compound treatment 0.459 0.183 2.61 0.44 0.197 3.31 4.1844 0.9931 3063406 Maybridge4_001931 CC(C)N(C(C)C)C(=O)NCc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H18 compound treatment 0.29 0.0135 0.19 0.185 -0.058 -0.97 -0.5513 -0.5557 3179498 Maybridge4_001932 Clc1ccc(cc1)c2nc(SCc3ccccc3)[nH]c(=S)c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H19 compound treatment 0.537 0.261 3.73 0.482 0.239 4.01 5.4718 0.9993 3063407 Maybridge4_001933 OC(=O)c1cc(F)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H20 compound treatment 0.505 0.229 3.27 0.391 0.148 2.48 4.0681 0.9908 1198061 Maybridge4_001934 CC(Oc1ccc(Cl)cc1Cl)c2n[nH]c(=S)n2CC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H21 compound treatment 0.515 0.239 3.41 0.365 0.122 2.05 3.8607 0.9702 3179499 Maybridge4_001935 FC(F)(F)C(NC1CCCCC1)(NC(=O)c2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H22 compound treatment 0.393 0.117 1.67 0.341 0.098 1.65 2.3419 1.0 1345621 Maybridge4_001936 O=c1[nH][nH]c(=O)n1CCCc2cc3cccc4ccc5cccc2c5c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H23 mock treatment 0.364 0.0875 1.25 0.257 0.014 0.24 1.0517 0.8257 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 H24 mock treatment 0.189 -0.0875 -1.25 0.243 3.12E-5 0.0 -0.8845 -0.7068 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I01 compound treatment 0.274 -0.00248 -0.04 0.239 -0.00397 -0.07 -0.0722 -0.9567 3179500 Maybridge4_001937 NC(=O)c1ccccc1NCC(=O)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I02 compound treatment 0.344 0.0675 0.97 0.293 0.05 0.84 1.2766 0.9976 1786031 Maybridge4_001938 S=c1[nH]nc(Cc2ccccc2)n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I03 compound treatment 0.497 0.221 3.15 0.247 0.00403 0.07 2.2782 0.7221 1416652 Maybridge4_001939 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I04 compound treatment 0.532 0.256 3.65 0.331 0.088 1.48 3.6291 0.9206 3179586 Maybridge4_001940 CNC(=O)NC(=O)CSc1nnc(Cc2ccccc2)n1c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I05 compound treatment 0.531 0.255 3.64 0.399 0.156 2.62 4.426 0.9869 3063409 Maybridge4_001941 Cn1cc(cn1)S(=O)(=O)Nc2ccc(Oc3c(Cl)cccc3Cl)nc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I06 compound treatment 0.441 0.165 2.35 0.437 0.194 3.26 3.9667 0.9873 3179587 Maybridge4_001942 Clc1ccccc1CC(C(=O)N2CCc3ccccc23)C(=O)N4CCc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I07 compound treatment 0.474 0.198 2.83 0.41 0.167 2.8 3.9801 1.0 3063410 Maybridge4_001943 CCOC(=O)c1cnn(C(=O)c2ccc(cc2)n3c(C)ccc3C)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I08 compound treatment 0.49 0.214 3.05 0.454 0.211 3.54 4.6641 0.9973 1500802 Maybridge4_001944 NC(=O)c1nnc2ccc(Cl)cc2c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I09 compound treatment 0.412 0.136 1.94 0.463 0.22 3.69 3.982 0.9547 1103360 Maybridge4_001945 FC(F)(F)c1ccc(cc1)C(=O)CN2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I10 compound treatment 0.471 0.195 2.78 0.508 0.265 4.45 5.1128 0.9745 3179588 Maybridge4_001946 O=C(CSc1nnc2NCCCn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I11 compound treatment 0.462 0.186 2.65 0.417 0.174 2.92 3.9418 0.9989 1721477 Maybridge4_001947 Cc1nn(c2NC3=C(C(c12)c4cccnc4)C(=O)CC(C)(C)C3)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I12 compound treatment 0.553 0.277 3.96 0.358 0.115 1.93 4.1619 0.9456 1444715 Maybridge4_001948 Cc1nc2cc(C)ccn2c1c3nnco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I13 compound treatment 0.477 0.201 2.87 0.39 0.147 2.47 3.773 0.9972 3063411 Maybridge4_001949 Cc1cc(C)c(C#N)c(Sc2ncnc3c2sc4nc(C)cc(C)c43)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I14 compound treatment 0.45 0.174 2.48 0.4 0.157 2.64 3.6186 0.9995 3179589 Maybridge4_001950 COc1ccc(cc1)n2c(n[nH]c2=S)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I15 compound treatment 0.401 0.125 1.78 0.457 0.214 3.59 3.7995 0.9476 3179590 Maybridge4_001951 CNC(=S)N1N=C2C(CCc3ccccc23)C1c4ccc(OC)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I16 compound treatment 0.42 0.144 2.05 0.321 0.078 1.31 2.3776 0.9764 3063412 Maybridge4_001952 CCOC(=O)N1CCc2c(C1)sc3[nH]c(=S)n(c4ccccc4)c(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I17 compound treatment 0.427 0.151 2.15 0.458 0.215 3.61 4.0744 0.9695 3179591 Maybridge4_001953 COc1cc2CCn3c(C(=O)c4cccs4)c(c(C#N)c3-c2cc1OC)c5ccc(C)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I18 compound treatment 0.44 0.164 2.34 0.397 0.154 2.59 3.4819 0.9988 3063413 Maybridge4_001954 Fc1ccc(CN2C(=O)/C(=C\c3ccc(F)cc3)/N=C2c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I19 compound treatment 0.504 0.228 3.25 0.367 0.124 2.08 3.7732 0.9767 3179592 Maybridge4_001955 CCC(C)[C@H](NC(=O)c1ccco1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I20 compound treatment 0.478 0.202 2.88 0.344 0.101 1.7 3.2372 0.968 3179593 Maybridge4_001956 COc1cccc(c1)C(=O)c2sc3nsc(SCc4ccccc4)c3c2N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I21 compound treatment 0.434 0.158 2.25 0.295 0.052 0.87 2.2107 0.9149 3063414 Maybridge4_001957 Cc1cc(C)c2c(N)c(sc2n1)c3nnc(SCC(=O)c4ccccc4)n3CC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I22 compound treatment 0.413 0.137 1.95 0.366 0.123 2.06 2.8409 0.9996 3179594 Maybridge4_001958 C=CCn1nc2CSc3ccccc3-n2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I23 mock treatment 0.345 0.0685 0.98 0.203 -0.04 -0.67 0.2186 0.1841 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 I24 mock treatment 0.263 -0.0135 -0.19 0.227 -0.016 -0.27 -0.3259 -0.987 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J01 compound treatment 0.292 0.0155 0.22 0.23 -0.013 -0.22 0.003 0.0097 3179595 Maybridge4_001959 CCOC(=O)CSc1nc(CN2c3ccccc3Sc4ccccc24)n[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J02 compound treatment 0.419 0.143 2.04 0.23 -0.013 -0.22 1.2875 0.628 1402836 Maybridge4_001960 NS(=O)(=O)c1ccc(Cl)cc1Sc2ccccc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J03 compound treatment 0.569 0.293 4.18 0.28 0.037 0.62 3.3981 0.8033 3179596 Maybridge4_001961 CCOC(=O)Cn1c(nc(c1c2ccccc2)c3ccccc3)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J04 compound treatment 0.543 0.267 3.81 0.351 0.108 1.81 3.9777 0.9423 1114912 Maybridge4_001962 NNC(=O)CNC(=O)c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J05 compound treatment 0.531 0.255 3.64 0.478 0.235 3.94 5.3636 0.9992 3179597 Maybridge4_001963 Fc1ccc(COc2nc(cc(c3ccco3)c2C#N)c4cccs4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J06 compound treatment 0.522 0.246 3.51 0.456 0.213 3.58 5.0115 1.0 3063348 Maybridge4_001964 FC(F)(F)C(NCc1ccccn1)(NC(=O)c2cccnc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J07 compound treatment 0.395 0.119 1.7 0.461 0.218 3.66 3.7863 0.9388 3179598 Maybridge4_001965 COc1ccc(/N=C/c2cn(cc2\C=N\c3ccc(OC)cc3)c4ccc(OC)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J08 compound treatment 0.143 -0.133 -1.91 0.158 -0.085 -1.43 -2.3585 -0.9897 1550362 Maybridge4_001966 OC(=O)c1ccccc1NC(=O)OCC2c3ccccc3-c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J09 compound treatment 0.137 -0.139 -2.0 0.164 -0.079 -1.33 -2.348 -0.9803 3179599 Maybridge4_001967 CC1(C)CC(=O)C=C(C1)Sc2nc3cc(Cl)ccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J10 compound treatment 0.479 0.203 2.9 0.4 0.157 2.64 3.912 0.9989 1156147 Maybridge4_001968 COc1ccc2nc3n(C)c(=O)n(C)c(=O)c3cc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J11 compound treatment 0.454 0.178 2.54 0.518 0.275 4.62 5.0595 0.9604 3179600 Maybridge4_001969 O=C1C2=C(NC(=S)NC2c3ccccc3)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J12 compound treatment 0.469 0.193 2.75 0.549 0.306 5.14 5.5792 0.9573 1727811 Maybridge4_001970 COc1cc(CCC(C)NC(=O)c2ccco2)ccc1OC(=O)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J13 compound treatment 0.416 0.14 2.0 0.455 0.212 3.56 3.9275 0.9626 3063350 Maybridge4_001971 COc1ccc(C#N)cc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J14 compound treatment 0.591 0.315 4.5 0.438 0.195 3.27 5.4957 0.9878 1014022 Maybridge4_001972 O=S(=O)(Cc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J15 compound treatment 0.475 0.199 2.84 0.477 0.234 3.93 4.7853 0.9873 3179601 Maybridge4_001973 Nc1n/c(=N\c2ccccc2)/n(c3ccccc3)c(=N)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J16 compound treatment 0.543 0.267 3.81 0.441 0.198 3.32 5.0459 0.9977 3063351 Maybridge4_001974 FC(F)(F)c1ccccc1/N=C/2\CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J17 compound treatment 0.535 0.259 3.7 0.419 0.176 2.95 4.7038 0.9938 3179602 Maybridge4_001975 COCOc1ccc(cc1OC)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J18 compound treatment 0.379 0.103 1.47 0.375 0.132 2.22 2.6038 0.9799 1465673 Maybridge4_001976 CC(Nc1ccccc1)(C#N)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J19 compound treatment 0.418 0.142 2.02 0.43 0.187 3.14 3.651 0.9775 3179603 Maybridge4_001977 c1ccc(cc1)c2nnc(o2)c3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J20 compound treatment 0.4 0.124 1.77 0.301 0.058 0.97 1.938 0.9606 1519121 Maybridge4_001978 CC(Oc1ccccc1c2ccccc2)c3n[nH]c(=S)n3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J21 compound treatment 0.46 0.184 2.62 0.407 0.164 2.75 3.8029 0.9997 3063353 Maybridge4_001979 COC(NC(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J22 compound treatment 0.518 0.242 3.45 0.325 0.082 1.38 3.4163 0.9187 1009264 Maybridge4_001980 CC(NC(=O)C)c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J23 mock treatment 0.402 0.126 1.8 0.24 -0.00297 -0.05 1.2343 0.6872 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 J24 mock treatment 0.251 -0.0255 -0.36 0.225 -0.018 -0.3 -0.471 -0.9956 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K01 compound treatment 0.279 0.00252 0.04 0.236 -0.00697 -0.12 -0.0573 -0.4679 3179604 Maybridge4_001981 OC(=O)CSCC(=O)N1CCCN(CC1)c2ccc(cn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K02 compound treatment 0.399 0.123 1.75 0.235 -0.00797 -0.13 1.1446 0.6512 3063380 Maybridge4_001982 CCOC(=O)c1nnn2c1nc(SCC(=O)N)c3ccccc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K03 compound treatment 0.476 0.2 2.85 0.297 0.054 0.91 2.6592 0.888 3179605 Maybridge4_001983 COc1ccc(NC(=O)c2ccc(CN3CCS(=O)(=O)CC3)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K04 compound treatment 0.46 0.184 2.62 0.317 0.074 1.24 2.7347 0.9417 3063381 Maybridge4_001984 CNC(=O)NC(=O)CSc1nnc(c2ccncc2)n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K05 compound treatment 0.407 0.131 1.87 0.313 0.07 1.18 2.1512 0.9751 3179606 Maybridge4_001985 S=C(NCC1CC(=NO1)c2ccccc2)NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K06 compound treatment 0.381 0.105 1.49 0.457 0.214 3.59 3.5972 0.9245 3179607 Maybridge4_001986 CCOc1nc-2c(Cc3ccccc32)c(c4ccco4)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K07 compound treatment 0.538 0.262 3.74 0.461 0.218 3.66 5.2326 0.9999 3063383 Maybridge4_001987 Sc1nnc(Cc2ccsc2)n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K08 compound treatment 0.548 0.272 3.88 0.384 0.141 2.37 4.4199 0.9718 3179608 Maybridge4_001988 O=c1[nH]c-2c(CCc3ccccc32)c(c1C#N)c4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K09 compound treatment 0.291 0.0145 0.21 0.287 0.044 0.74 0.6694 0.872 3063384 Maybridge4_001989 C=CCSc1c2CCCc2c(C#N)c3nc4ccccc4n13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K10 compound treatment 0.502 0.226 3.23 0.379 0.136 2.28 3.8954 0.9857 3179609 Maybridge4_001990 O=C(N1CCCn2c(SCc3ccccc3)nnc12)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K11 compound treatment 0.508 0.232 3.31 0.313 0.07 1.18 3.1727 0.9029 3063386 Maybridge4_001991 CCNC(=S)Nc1sc2CC(C)CCc2c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K12 compound treatment 0.512 0.236 3.37 0.335 0.092 1.54 3.4743 0.9375 3179610 Maybridge4_001992 Cc1sc2nc3SCC(=Nn3c(=O)c2c1C)c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K13 compound treatment 0.378 0.102 1.45 0.492 0.249 4.18 3.9823 0.9 3063387 Maybridge4_001993 CCOC(=O)c1oc2nc(cc(c3ccco3)c2c1N)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K14 compound treatment 0.425 0.149 2.12 0.388 0.145 2.43 3.2234 0.9977 3179611 Maybridge4_001994 C1Sc2ccccc2-n3c(nnc13)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K15 compound treatment 0.548 0.272 3.88 0.423 0.18 3.02 4.8828 0.9923 3179694 Maybridge4_001995 CCOC(=O)c1nnn2c1n(C)c(=O)c3ccccc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K16 compound treatment 0.498 0.222 3.17 0.355 0.112 1.88 3.5701 0.969 3063389 Maybridge4_001996 O=c1c(nnc2sc3ccccc3n12)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K17 compound treatment 0.503 0.227 3.24 0.355 0.112 1.88 3.6206 0.9665 3179695 Maybridge4_001997 CCOC(=O)C1=NN(C2C1c3cccc4cccc2c34)c5ccc(C)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K18 compound treatment 0.56 0.284 4.06 0.41 0.167 2.8 4.8499 0.9837 3063390 Maybridge4_001998 Clc1ccccc1/C=C\2/N=C(N(CC=C)C2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K19 compound treatment 0.424 0.148 2.11 0.396 0.153 2.57 3.3082 0.9952 3179696 Maybridge4_001999 O=C(NCC1COc2ccccc2O1)Nc3csc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K20 compound treatment 0.41 0.134 1.91 0.324 0.081 1.36 2.3121 0.9862 3179697 Maybridge4_002000 CNC(=O)NC(=O)CSc1ncnc2sc(cc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K21 compound treatment 0.357 0.0805 1.15 0.366 0.123 2.06 2.2745 0.962 3063391 Maybridge4_002001 Cc1cc(C)c2c(N)c(sc2n1)c3nnc(SCc4ccc(Cl)cc4)n3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K22 compound treatment 0.409 0.133 1.9 0.294 0.051 0.86 1.9459 0.9355 3179698 Maybridge4_002002 S=c1[nH]nc(CSc2nc(cn2c3ccccc3)c4ccccc4)n1c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K23 mock treatment 0.33 0.0535 0.77 0.289 0.046 0.77 1.0876 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 K24 mock treatment 0.263 -0.0135 -0.19 0.235 -0.00797 -0.13 -0.231 -0.984 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L01 compound treatment 0.309 0.0325 0.47 0.216 -0.027 -0.45 0.0088 0.0136 3063422 Maybridge4_002003 CCOC(=O)CSc1nc(SCC(=O)OCC)c2c3CCCc3sc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L02 compound treatment 0.293 0.0165 0.24 0.216 -0.027 -0.45 -0.153 -0.2997 1536081 Maybridge4_002004 OC(=O)c1ccccc1Sc2ccccc2S(=O)(=O)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L03 compound treatment 0.474 0.198 2.83 0.247 0.00403 0.07 2.0456 0.7238 3179699 Maybridge4_002005 C=CCn1c(nc(c1c2ccccc2)c3ccccc3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L04 compound treatment 0.471 0.195 2.78 0.294 0.051 0.86 2.573 0.8839 1430538 Maybridge4_002006 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L05 compound treatment 0.431 0.155 2.21 0.396 0.153 2.57 3.379 0.9972 3179700 Maybridge4_002007 N=c1n(Nc2ccccc2)cnc3sc4CCCc4c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L06 compound treatment 0.454 0.178 2.54 0.362 0.119 2.0 3.2081 0.993 3063426 Maybridge4_002008 Cc1ccc(cc1)C(=O)NC(NCc2ccco2)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L07 compound treatment 0.459 0.183 2.61 0.431 0.188 3.16 4.0776 0.9956 3179701 Maybridge4_002009 Brc1ccc(s1)c2ccc(Br)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L08 compound treatment 0.48 0.204 2.91 0.412 0.169 2.84 4.0645 0.9999 1371799 Maybridge4_002010 CCOC(=O)C(C)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L09 compound treatment 0.552 0.276 3.94 0.404 0.161 2.7 4.6978 0.9831 1134767 Maybridge4_002011 C1C(=Cc2ccccc12)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L10 compound treatment 0.567 0.291 4.16 0.387 0.144 2.42 4.6477 0.9668 1364288 Maybridge4_002012 O=C(NC1CCN(CC1)C(=O)C2CCC2)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L11 compound treatment 0.413 0.137 1.95 0.394 0.151 2.53 3.1732 0.9917 1570440 Maybridge4_002013 Oc1cc(Cc2ccccc2)cnc1CN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L12 compound treatment 0.391 0.115 1.64 0.253 0.01 0.17 1.2773 0.7757 1227426 Maybridge4_002014 CC(C)C1CCC(C)CC1N(Cc2ccccc2)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L13 compound treatment 0.593 0.317 4.53 0.423 0.18 3.02 5.3379 0.9807 1583701 Maybridge4_002015 N[C@@H](CO)CSCc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L14 compound treatment 0.519 0.243 3.47 0.368 0.125 2.1 3.9367 0.971 1368346 Maybridge4_002016 COc1cc(CCc2cc(OC)c(C)cc2OC)c(OC)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L15 compound treatment 0.515 0.239 3.41 0.367 0.124 2.08 3.8844 0.9719 3063428 Maybridge4_002017 FC(F)(F)C(NC(=O)c1ccccc1)(Nc2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L16 compound treatment 0.433 0.157 2.24 0.37 0.127 2.13 3.0907 0.9997 1023708 Maybridge4_002018 COc1ccc(cc1)c2nc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L17 compound treatment 0.487 0.211 3.01 0.342 0.099 1.66 3.3045 0.9608 1344186 Maybridge4_002019 CC(=O)N1C(C(=O)NC1=S)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L18 compound treatment 0.455 0.179 2.55 0.371 0.128 2.15 3.325 0.9963 3179703 Maybridge4_002020 CC(C)C(C)(Nc1ccccc1)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L19 compound treatment 0.494 0.218 3.11 0.418 0.175 2.94 4.2773 0.9996 1047316 Maybridge4_002021 OC(=O)c1ccc(s1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L20 compound treatment 0.471 0.195 2.78 0.366 0.123 2.06 3.4275 0.9892 3179704 Maybridge4_002022 Brc1ccccc1C(=O)c2ccc-3c(c2)C(=O)c4ccccc43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L21 compound treatment 0.435 0.159 2.27 0.433 0.19 3.19 3.8586 0.986 3063451 Maybridge4_002023 FC(F)(F)C(NC(=O)c1ccccc1)(OCc2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L22 compound treatment 0.489 0.213 3.04 0.279 0.036 0.6 2.5771 0.8315 3179705 Maybridge4_002024 CCOC(=O)CSc1nncc(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L23 mock treatment 0.331 0.0545 0.78 0.282 0.039 0.66 1.0146 0.9962 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 L24 mock treatment 0.286 0.00952 0.14 0.253 0.01 0.17 0.2153 0.9944 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M01 compound treatment 0.282 0.00552 0.08 0.289 0.046 0.77 0.6021 0.7753 3063453 Maybridge4_002025 Cc1ccc(CNC(=O)Nc2ccccc2)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M02 compound treatment 0.28 0.00352 0.05 0.281 0.038 0.64 0.4869 0.7605 3179706 Maybridge4_002026 CCOC(=O)c1nnn2c1nc(SCc3ccc(F)cc3)c4ccccc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M03 compound treatment 0.592 0.316 4.51 0.315 0.072 1.21 4.0461 0.866 3179707 Maybridge4_002027 O=C(Nc1ccc(OCc2ccccc2)cc1)OCC3CN(Cc4ccccc4)CCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M04 compound treatment 0.428 0.152 2.17 0.265 0.022 0.37 1.7939 0.816 3063456 Maybridge4_002028 O=C(CC(C(=O)N1CCc2ccccc12)C(=O)N3CCc4ccccc34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M05 compound treatment 0.501 0.225 3.21 0.377 0.134 2.25 3.8615 0.9848 3179708 Maybridge4_002029 O=C(OCC1CC(=NO1)c2ccccc2)c3cccc(n3)C(=O)OCC4CC(=NO4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M06 compound treatment 0.418 0.142 2.02 0.107 -0.136 -2.28 -0.1824 -0.0598 3063457 Maybridge4_002030 CC1=Nn2c(Cn3nnc4ccccc34)nnc2SC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M07 compound treatment 0.567 0.291 4.16 0.396 0.153 2.57 4.7545 0.9733 3179709 Maybridge4_002031 C/C(=N\O)/C(C)(C)Nc1ccc(cc1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M08 compound treatment 0.329 0.0525 0.75 0.243 3.12E-5 0.0 0.5315 0.7076 3063458 Maybridge4_002032 O=C(Oc1cc(=O)oc2c3cccc4CCn(c(=O)c12)c43)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M09 compound treatment 0.217 -0.0595 -0.85 0.103 -0.14 -2.35 -2.2628 -0.9056 2096080 Maybridge4_002033 CCOC(=O)c1sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c2c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M10 compound treatment 0.4 0.124 1.77 0.357 0.114 1.91 2.6026 0.9992 3179710 Maybridge4_002034 CCOC(=O)N1CCc2c(C#N)c(NC(=O)CN3CCc4ccccc34)sc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M11 compound treatment 0.483 0.207 2.95 0.28 0.037 0.62 2.5282 0.8375 3063459 Maybridge4_002035 O=C(COc1nc(cc(c2cccs2)c1C#N)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M12 compound treatment 0.404 0.128 1.82 0.458 0.215 3.61 3.8417 0.95 3063460 Maybridge4_002036 O=c1n(CN2CCOCC2)nc3sc4ccccc4n3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M13 compound treatment 0.421 0.145 2.07 0.361 0.118 1.98 2.8625 0.9998 3179711 Maybridge4_002037 Nc1c(oc2nc(cc(c3cccs3)c12)c4ccco4)C(=O)c5ccc(Cl)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M14 compound treatment 0.439 0.163 2.32 0.427 0.184 3.09 3.8278 0.9902 3063486 Maybridge4_002038 Cc1nc2n(ncc2c(=O)n1NC(=O)Nc3ccc(Cl)c(Cl)c3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M15 compound treatment 0.399 0.123 1.75 0.4 0.157 2.64 3.1028 0.9803 3179712 Maybridge4_002039 CCOC(=O)c1nnn2c1n(CC=C)c(=O)c3ccccc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M16 compound treatment 0.407 0.131 1.87 0.395 0.152 2.55 3.1244 0.9882 3063487 Maybridge4_002040 COC(=O)C1=C(C)N=C2SC(=C(N)N2C1c3cccs3)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M17 compound treatment 0.367 0.0905 1.29 0.397 0.154 2.59 2.7436 0.9489 3179713 Maybridge4_002041 O=C/1NN=C(\C1=C\2/OC(=CS2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M18 compound treatment 0.429 0.153 2.18 0.439 0.196 3.29 3.8691 0.9801 3179714 Maybridge4_002042 Clc1ccc(CN2C(=O)/C(=C\c3cccs3)/N=C2c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M19 compound treatment 0.402 0.126 1.8 0.331 0.088 1.48 2.3143 0.9953 3063489 Maybridge4_002043 COc1ccc(cc1)n2ncc(NC(=O)N3CCOCC3)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M20 compound treatment 0.391 0.115 1.64 0.329 0.086 1.44 2.1793 0.998 3179715 Maybridge4_002044 O=c1c(nc(nn1CN2CCOCC2)c3ccccc3)C(CN4CCOCC4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M21 compound treatment 0.401 0.125 1.78 0.286 0.043 0.72 1.7701 0.921 3063490 Maybridge4_002045 Clc1ccccc1C2C3CCc4ccccc4C3=NN2C(=O)c5cccs5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M22 compound treatment 0.404 0.128 1.82 0.287 0.044 0.74 1.8123 0.9209 3179716 Maybridge4_002046 CCOC(=O)c1cnc(nc1N)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M23 mock treatment 0.263 -0.0135 -0.19 0.275 0.032 0.54 0.2438 0.4268 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 M24 mock treatment 0.272 -0.00448 -0.06 0.251 0.00803 0.13 0.05 0.3347 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N01 compound treatment 0.309 0.0325 0.47 0.268 0.025 0.42 0.6259 0.9987 3063492 Maybridge4_002047 O=C1CSc2nnc(c3ccccc3)n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N02 compound treatment 0.282 0.00552 0.08 0.234 -0.00897 -0.15 -0.0507 -0.298 1229835 Maybridge4_002048 OC(=O)c1ccccc1Sc2ccccc2S(=O)(=O)NC3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N03 compound treatment 0.47 0.194 2.77 0.237 -0.00597 -0.1 1.8864 0.6811 1256899 Maybridge4_002049 c1csc(c1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N04 compound treatment 0.538 0.262 3.74 0.253 0.01 0.17 2.7641 0.7382 3178130 Maybridge4_002050 CCCc1cc(O)nc(SC/C=C/c2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N05 compound treatment 0.384 0.108 1.54 0.243 3.12E-5 0.0 1.0878 0.7073 3178131 Maybridge4_002051 CCNc1nc(SCC(=O)NC(=O)NCc2ccccc2)nc3sc4CN(C)CCc4c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N06 compound treatment 0.416 0.14 2.0 0.271 0.028 0.47 1.7438 0.8505 3063494 Maybridge4_002052 CC1CN=C(S1)N(C2CCCCC2)C(=O)Nc3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N07 compound treatment 0.429 0.153 2.18 0.257 0.014 0.24 1.7091 0.7789 3178132 Maybridge4_002053 Cc1ccc(OC(=O)OCSc2nnn[nH]2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N08 compound treatment 0.433 0.157 2.24 0.314 0.071 1.19 2.426 0.9565 1423044 Maybridge4_002054 CC(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N09 compound treatment 0.407 0.131 1.87 0.281 0.038 0.64 1.7714 0.8978 1177114 Maybridge4_002055 Brc1ccc(cc1)N2C(=O)C3=C(C2=O)C(=NCCN3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N10 compound treatment 0.476 0.2 2.85 0.303 0.06 1.01 2.7304 0.9022 1659522 Maybridge4_002056 Clc1cccc(Cl)c1C(=O)N2CCC(CC2)NC(=O)C3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N11 compound treatment 0.526 0.25 3.57 0.285 0.042 0.71 3.0225 0.8308 1381385 Maybridge4_002057 CN1C(=O)N(c2ccc(Cl)cc2)C(C)(O)CC1(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N12 compound treatment 0.362 0.0855 1.22 0.276 0.033 0.55 1.2569 0.9359 1409714 Maybridge4_002058 COc1cccc(NC(=O)c2ccc(OC)c(OC)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N13 compound treatment 0.46 0.184 2.62 0.299 0.056 0.94 2.5211 0.9042 1704266 Maybridge4_002059 CC(C)(C)C(=O)Nc1ccccc1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N14 compound treatment 0.391 0.115 1.64 0.294 0.051 0.86 1.7639 0.9543 3178133 Maybridge4_002060 NNC(=O)c1cc(S)ncn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N15 compound treatment 0.428 0.152 2.17 0.285 0.042 0.71 2.0313 0.8912 3063524 Maybridge4_002061 CC(=O)NC(Nc1ccccc1)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N16 compound treatment 0.422 0.146 2.08 0.351 0.108 1.81 2.7539 0.9976 3178134 Maybridge4_002062 C/C(=N\c1ccccc1C(F)(F)F)/c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N17 compound treatment 0.416 0.14 2.0 0.325 0.082 1.38 2.3847 0.9836 1020871 Maybridge4_002063 O=C1NC(C(=O)N1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N18 compound treatment 0.44 0.164 2.34 0.29 0.047 0.79 2.212 0.8961 1667495 Maybridge4_002064 Clc1ccc2[nH]c(=O)c3nc(oc3c2c1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N19 compound treatment 0.285 0.00852 0.12 0.17 -0.073 -1.22 -0.7799 -0.6336 1670169 Maybridge4_002065 CC(C)c1ccc(cc1)S(=O)(=O)CC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N20 compound treatment 0.472 0.196 2.8 0.285 0.042 0.71 2.4763 0.8586 1596128 Maybridge4_002066 CCOC(=O)C1CCN(C1=O)S(=O)(=O)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N21 compound treatment 0.376 0.0995 1.42 0.232 -0.011 -0.18 0.8764 0.6106 1008385 Maybridge4_002067 O=C(c1ccccc1)c2ccccc2C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N22 compound treatment 0.378 0.102 1.45 0.294 0.051 0.86 1.6324 0.9683 1546853 Maybridge4_002068 Cn1c(=O)n(C)c2ncn(CC(O)CN(CC=C)CC=C)c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N23 mock treatment 0.258 -0.0185 -0.26 0.328 0.085 1.43 0.8222 0.5665 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 N24 mock treatment 0.285 0.00852 0.12 0.241 -0.00197 -0.03 0.0628 0.4973 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O01 compound treatment 0.271 -0.00548 -0.08 0.246 0.00303 0.05 -0.0195 -0.2085 3063527 Maybridge4_002069 O=C(Nc1sccc1c2nc3ccccc3s2)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O02 compound treatment 0.317 0.0405 0.58 0.308 0.065 1.09 1.1816 0.9561 3178135 Maybridge4_002070 CCOC(=O)CSc1nnc(Cn2nnc3ccccc23)n1c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O03 compound treatment 0.287 0.0105 0.15 0.244 0.00103 0.02 0.1186 0.7833 3063528 Maybridge4_002071 Cc1ccc(cc1)S(=O)(=O)NC(=O)OCC2CN(Cc3ccccc3)CCO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O04 compound treatment 0.295 0.0185 0.26 0.213 -0.03 -0.5 -0.1684 -0.2962 3178136 Maybridge4_002072 Cn1nc2c3ccccc3n(CC=C)c2nc1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O05 compound treatment 0.153 -0.123 -1.77 0.181 -0.062 -1.04 -1.9844 -0.9681 3178137 Maybridge4_002073 Clc1ccc(cc1)n2ncc(n2)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O06 compound treatment 0.232 -0.0445 -0.64 0.248 0.00503 0.08 -0.3902 -0.6079 3178138 Maybridge4_002074 Brc1ccc(cc1)C2=Nn3c(Cn4nnc5ccccc45)nnc3SC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O07 compound treatment 0.29 0.0135 0.19 0.268 0.025 0.42 0.4338 0.938 1760428 Maybridge4_002075 O=C(Nc1ccc2OCCOc2c1)c3ccc4nccnc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O08 compound treatment 0.253 -0.0235 -0.34 0.257 0.014 0.24 -0.071 -0.1731 3178139 Maybridge4_002076 CNC(=O)NC(=O)CSc1nnc(o1)c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O09 compound treatment 0.269 -0.00748 -0.11 0.254 0.011 0.19 0.0552 0.2582 3178140 Maybridge4_002077 CCOC(=O)COc1c(C#N)sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O10 compound treatment 0.24 -0.0365 -0.52 0.213 -0.03 -0.5 -0.7247 -0.9998 3063548 Maybridge4_002078 S=c1[nH]c(=S)c2cnc(nc2[nH]1)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O11 compound treatment 0.276 -4.84E-4 -0.01 0.216 -0.027 -0.45 -0.325 -0.7178 1200067 Maybridge4_002079 Cc1cc(C)c2c(N)c(sc2n1)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O12 compound treatment 0.258 -0.0185 -0.26 0.225 -0.018 -0.3 -0.4002 -0.9978 2102976 Maybridge4_002080 COc1ccc(cc1)C2=Nn3c(SC2)nc4sc5CCCCc5c4c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O13 compound treatment 0.058 -0.218 -3.13 0.115 -0.128 -2.15 -3.7285 -0.9833 3063550 Maybridge4_002081 Cc1cc(C)c(C#N)c(Sc2ncnc3n(Cc4ccccc4)nnc23)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O14 compound treatment 0.302 0.0255 0.36 0.246 0.00303 0.05 0.2941 0.798 3178141 Maybridge4_002082 O=c1n(/N=C/c2cccs2)cnc3sc(cc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O15 compound treatment 0.271 -0.00548 -0.08 0.228 -0.015 -0.25 -0.2331 -0.8857 3178142 Maybridge4_002083 CCOC(=O)c1nnn2c1n(Cc3ccc(Cl)cc3)c(=O)c4ccccc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O16 compound treatment 0.282 0.00552 0.08 0.222 -0.021 -0.35 -0.1931 -0.5353 3063551 Maybridge4_002084 COc1cc(/C=N/n2c(C)nc3n(cnc3c2=O)c4ccccc4)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O17 compound treatment 0.301 0.0245 0.35 0.22 -0.023 -0.39 -0.0246 -0.0473 3178143 Maybridge4_002085 O=c1nc2n(nc(c3ccccc3)n2c(c1C#N)c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O18 compound treatment 0.277 5.16E-4 0.01 0.218 -0.025 -0.42 -0.2911 -0.6945 3063552 Maybridge4_002086 C1Cc2ccccc2N1c3ncnc4sc(cc34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O19 compound treatment 0.265 -0.0115 -0.16 0.25 0.00703 0.12 -0.0327 -0.1617 3178144 Maybridge4_002087 COc1ccc(cc1)n2ncc(NC(=O)Nc3ccc4OCCCOc4c3)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O20 compound treatment 0.236 -0.0405 -0.58 0.211 -0.032 -0.54 -0.7889 -0.9993 3063553 Maybridge4_002088 Nc1ncnc2nc(ncc12)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O21 compound treatment 0.235 -0.0415 -0.59 0.305 0.062 1.04 0.3166 0.2642 3178145 Maybridge4_002089 CC(=O)N1N=C2C(CCc3ccccc23)C1c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O22 compound treatment 0.23 -0.0465 -0.66 0.216 -0.027 -0.45 -0.7902 -0.9824 3063554 Maybridge4_002090 Cc1cc(=O)n2ncnc2n1CC(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O23 mock treatment 0.22 -0.0565 -0.81 0.244 0.00103 0.02 -0.5591 -0.6918 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 O24 mock treatment 0.258 -0.0185 -0.26 0.189 -0.054 -0.91 -0.8275 -0.8769 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P01 compound treatment 0.231 -0.0455 -0.65 0.213 -0.03 -0.5 -0.8157 -0.9919 1504248 Maybridge4_002091 C1Cc2ccccc2N1c3ncnc4n(ncc34)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P02 compound treatment 0.282 0.00552 0.08 0.277 0.034 0.57 0.4597 0.7972 1485949 Maybridge4_002092 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)c3ccc(cc3)C(C)(C)C)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P03 compound treatment 0.27 -0.00648 -0.09 0.28 0.037 0.62 0.3739 0.595 3063615 Maybridge4_002093 O=C/1NNC(=N\C1=C/c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P04 compound treatment 0.275 -0.00148 -0.02 0.295 0.052 0.87 0.6025 0.6897 3178146 Maybridge4_002094 Cn1cnnc1Sc2cc(C#N)c(C#N)cc2Sc3nncn3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P05 compound treatment 0.287 0.0105 0.15 0.243 3.12E-5 0.0 0.1067 0.7096 3063618 Maybridge4_002095 CCNc1nc(SCc2ccc(Cl)cc2)nc3sc4CN(C)CCc4c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P06 compound treatment 0.218 -0.0585 -0.84 0.242 -9.69E-4 -0.02 -0.603 -0.7207 3178147 Maybridge4_002096 Cn1cnc(c1C#N)n2oo2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P07 compound treatment 0.256 -0.0205 -0.29 0.278 0.035 0.59 0.2086 0.3175 1405262 Maybridge4_002097 O=C(NCc1ccccc1)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P08 compound treatment 0.337 0.0605 0.87 0.28 0.037 0.62 1.0516 0.9868 1585718 Maybridge4_002098 CCOC(=O)C(C)Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P09 compound treatment 0.242 -0.0345 -0.49 0.24 -0.00297 -0.05 -0.384 -0.7746 3178148 Maybridge4_002099 COC(=O)/C(=C/C(=O)c1c(F)c(F)c(OC)c(F)c1F)/O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P10 compound treatment 0.229 -0.0475 -0.68 0.236 -0.00697 -0.12 -0.563 -0.8169 1497616 Maybridge4_002100 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)C3CCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P11 compound treatment 0.227 -0.0495 -0.71 0.219 -0.024 -0.4 -0.785 -0.9642 3178149 Maybridge4_002101 O=c1ccc2CCCCc2n1CCC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P12 compound treatment 0.203 -0.0735 -1.05 0.205 -0.038 -0.64 -1.1938 -0.9713 1054556 Maybridge4_002102 Cc1ccc(NS(=O)(=O)c2ccccc2)c(NS(=O)(=O)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P13 compound treatment 0.25 -0.0265 -0.38 0.285 0.042 0.71 0.231 0.2884 1043550 Maybridge4_002103 OC1CCN(Cc2ccccc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P14 compound treatment 0.25 -0.0265 -0.38 0.237 -0.00597 -0.1 -0.3387 -0.8644 1240290 Maybridge4_002104 CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P15 compound treatment 0.253 -0.0235 -0.34 0.226 -0.017 -0.28 -0.4389 -0.9966 3063648 Maybridge4_002105 CC(=O)NC(NCc1ccccc1)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P16 compound treatment 0.271 -0.00548 -0.08 0.252 0.00903 0.15 0.0517 0.303 3178234 Maybridge4_002106 CC(C)[C@H]1COC(=N1)c2cccc(n2)C3=N[C@H](CO3)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P17 compound treatment 0.234 -0.0425 -0.61 0.232 -0.011 -0.18 -0.5599 -0.8818 3063650 Maybridge4_002107 CC(O)/C=C/c1cccc[n+]1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P18 compound treatment 0.29 0.0135 0.19 0.284 0.041 0.69 0.6237 0.8719 3178235 Maybridge4_002108 CCOC(=O)C1=C(C)N(C(=O)Oc2ccccc2)C(=NC1c3ccccc3)SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P19 compound treatment 0.358 0.0815 1.17 0.242 -9.69E-4 -0.02 0.813 0.6972 3063651 Maybridge4_002109 CN1C(=O)/C(=C\Nc2ccc(Cl)cc2)/C(=O)c3c1n(C)c(=O)n(C)c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P20 compound treatment 0.312 0.0355 0.51 0.234 -0.00897 -0.15 0.2528 0.4771 1466385 Maybridge4_002110 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OC)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P21 compound treatment 0.268 -0.00848 -0.12 0.318 0.075 1.26 0.8047 0.636 1646281 Maybridge4_002111 COc1cccc(c1)c2ncc(o2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P22 compound treatment 0.25 -0.0265 -0.38 0.237 -0.00597 -0.1 -0.3387 -0.8644 1592521 Maybridge4_002112 O=C(Nc1ccccc1)N(Cc2ccccc2)c3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P23 mock treatment 0.279 0.00252 0.04 0.243 3.12E-5 0.0 0.0258 0.7173 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2054 P24 mock treatment 0.212 -0.0645 -0.92 0.221 -0.022 -0.37 -0.9129 -0.9191 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A01 compound treatment 0.232 0.00753 0.11 0.206 -0.00788 -0.13 -0.0173 -0.1014 3178236 Maybridge4_002113 CCOC(=O)c1c(C)n[nH]c1/N=C/c2ccc(OC)c(OC)c2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A02 compound treatment 0.236 0.0115 0.16 0.288 0.0741 1.24 0.9964 0.7939 3178237 Maybridge4_002114 CS/C(=C(/C#N)\S(=O)(=O)c1ccc(Cl)cc1)/NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A03 compound treatment 0.219 -0.00547 -0.08 0.299 0.0851 1.43 0.955 0.6674 1739670 Maybridge4_002115 O=C(C(C(=O)N1CCCCC1)C2(CC3CC4CC(C3)C2)C4)N5CCCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A04 compound treatment 0.249 0.0245 0.35 0.249 0.0351 0.59 0.665 0.9693 3178238 Maybridge4_002116 CSc1c(C#N)c(nn1C)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A05 compound treatment 0.241 0.0165 0.24 0.252 0.0381 0.64 0.6197 0.9084 3063681 Maybridge4_002117 CN(C)c1nc(O)nc(n1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A06 compound treatment 0.242 0.0175 0.25 0.218 0.00412 0.07 0.2263 0.8698 3178239 Maybridge4_002118 CN1c2ccccc2C(=O)/C(=C\Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)/S1(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A07 compound treatment 0.227 0.00253 0.04 0.23 0.0161 0.27 0.217 0.7946 1532269 Maybridge4_002119 COc1cc2CCN=C(c3ccccc3NC(=O)c4cccc(Cl)c4)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A08 compound treatment 0.213 -0.0115 -0.16 0.239 0.0251 0.42 0.1822 0.4026 1424615 Maybridge4_002120 CCCS(=O)(=O)C1=C(N)OC(=C(C#N)C1c2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A09 compound treatment 0.244 0.0195 0.28 0.207 -0.00688 -0.12 0.116 0.3836 1227957 Maybridge4_002121 Cc1cc(N(S(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)n(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A10 compound treatment 0.234 0.00953 0.14 0.236 0.0221 0.37 0.359 0.9075 3063685 Maybridge4_002122 CS/C(=C(/C#N)\C(=O)c1ccc(Cl)cc1)/NCC2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A11 compound treatment 0.229 0.00453 0.06 0.229 0.0151 0.25 0.2253 0.8601 1505422 Maybridge4_002123 O=C(Nc1cc(nn1c2ccccc2)C3CC3)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A12 compound treatment 0.207 -0.0175 -0.25 0.229 0.0151 0.25 0.0028 0.0079 3063686 Maybridge4_002124 CC(C)S(=O)(=O)/C(=C/Nc1ncccn1)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A13 compound treatment 0.217 -0.00747 -0.11 0.181 -0.0329 -0.55 -0.4657 -0.8286 1730851 Maybridge4_002125 Cc1ccc(cc1)C2C(=C(N)OC(=C2C#N)C3CC3)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A14 compound treatment 0.245 0.0205 0.29 0.201 -0.0129 -0.22 0.0549 0.1505 3063688 Maybridge4_002126 Cn1ccnc1S(=O)(=O)/C(=C/c2ccc3OCOc3c2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A15 compound treatment 0.211 -0.0135 -0.19 0.217 0.00312 0.05 -0.0991 -0.4965 1337308 Maybridge4_002127 CCOC(=O)c1cnc2n(C)nc(C3CC3)c2c1N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A16 compound treatment 0.213 -0.0115 -0.16 0.211 -0.00288 -0.05 -0.1501 -0.8779 3063690 Maybridge4_002128 Cc1cc(nc2c(Br)c(nn12)C(C)(C)C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A17 compound treatment 0.192 -0.0325 -0.46 0.202 -0.0119 -0.2 -0.4693 -0.9287 1574781 Maybridge4_002129 COc1c(Cl)scc1NC(=O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A18 compound treatment 0.229 0.00453 0.06 0.227 0.0131 0.22 0.2016 0.8779 3063692 Maybridge4_002130 CSC(=C(C#N)C(=O)c1cccc(c1)C(F)(F)F)SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A19 compound treatment 0.209 -0.0155 -0.22 0.207 -0.00688 -0.12 -0.238 -0.9539 3178240 Maybridge4_002131 Clc1ccccc1C(=O)C(=C2SCCCS2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A20 compound treatment 0.213 -0.0115 -0.16 0.214 1.25E-4 0.0 -0.1145 -0.698 1150123 Maybridge4_002132 CC(C)CC(NC(=O)Cc1ccsc1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A21 compound treatment 0.244 0.0195 0.28 0.232 0.0181 0.3 0.4127 0.9991 3063728 Maybridge4_002133 COc1cccc(c1)c2nc(N)nc(SC)c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A22 compound treatment 0.233 0.00853 0.12 0.234 0.0201 0.34 0.3251 0.9053 3178241 Maybridge4_002134 Fc1ccc(N/C=C(\C#N)/S(=O)(=O)Cc2ccco2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A23 mock treatment 0.223 -0.00147 -0.02 0.216 0.00212 0.04 0.0104 0.2504 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 A24 mock treatment 0.207 -0.0175 -0.25 0.201 -0.0129 -0.22 -0.3295 -0.9974 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B01 compound treatment 0.269 0.0445 0.64 0.251 0.0371 0.62 0.891 0.9999 3178242 Maybridge4_002135 FC(F)(F)c1cc(CN/C=C(\C#N)/S(=O)(=O)Cc2ccco2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B02 compound treatment 0.241 0.0165 0.24 0.232 0.0181 0.3 0.3823 0.9922 3063731 Maybridge4_002136 COC(=O)c1ccc2C(=O)/C(=C/Nc3ccc(Cl)cc3)/S(=O)(=O)N(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B03 compound treatment 0.261 0.0365 0.52 0.262 0.0481 0.81 0.9406 0.9778 3178243 Maybridge4_002137 CSc1sc(/C(=N\O)/C)c2CC(C)(C)C/C(=N/O)/c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B04 compound treatment 0.278 0.0535 0.77 0.258 0.0441 0.74 1.0651 0.9999 3063732 Maybridge4_002138 COC(=O)c1sc(SC)c(c1C)c2ccon2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B05 compound treatment 0.273 0.0485 0.69 0.235 0.0211 0.35 0.7416 0.9514 3178244 Maybridge4_002139 Clc1ccc(Sc2ccccc2CN/C(=C(\N=C\c3cccs3)/C#N)/C#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B06 compound treatment 0.237 0.0125 0.18 0.231 0.0171 0.29 0.33 0.9742 3063733 Maybridge4_002140 CN(C)/C=C/C(=O)c1ccc2OC(C)(C)CCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B07 compound treatment 0.235 0.0105 0.15 0.227 0.0131 0.22 0.2623 0.9828 1330787 Maybridge4_002141 Clc1ccc(cc1)C(=O)N(CCS(=O)(=O)c2ccc(Cl)cc2)Cc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B08 compound treatment 0.231 0.00653 0.09 0.233 0.0191 0.32 0.293 0.8765 3063734 Maybridge4_002142 Clc1ccc(cc1)S(=O)(=O)C(=C2SCCCCS2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B09 compound treatment 0.254 0.0295 0.42 0.242 0.0281 0.47 0.6325 0.9985 1191188 Maybridge4_002143 CSc1scc2CCc3cn(nc3-c12)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B10 compound treatment 0.259 0.0345 0.49 0.24 0.0261 0.44 0.6593 0.9982 1483249 Maybridge4_002144 CC1(C)CCc2cc(ccc2O1)c3ccn(n3)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B11 compound treatment 0.281 0.0565 0.81 0.282 0.0681 1.14 1.3803 0.9856 3178245 Maybridge4_002145 Cc1csc2sc(C(=O)c3ccc(Cl)cc3)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B12 compound treatment 0.246 0.0215 0.31 0.213 -8.75E-4 -0.01 0.2074 0.6726 3063735 Maybridge4_002146 FC(F)(F)c1cc(n2ncc(C(=O)NC(=S)Nc3ccccc3Cl)c2n1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B13 compound treatment 0.226 0.00153 0.02 0.233 0.0191 0.32 0.2425 0.7536 1629969 Maybridge4_002147 CCOC(=O)c1sc(SC)c-2c1CCc3cnc(SC)nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B14 compound treatment 0.241 0.0165 0.24 0.218 0.00412 0.07 0.2162 0.8773 3178246 Maybridge4_002148 CC(C)CSc1nnc(CSCc2nc(cs2)c3ccc(Cl)cc3)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B15 compound treatment 0.231 0.00653 0.09 0.218 0.00412 0.07 0.115 0.9891 1122221 Maybridge4_002149 Clc1ccc(cc1)C2CC(=CC(=S)S2)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B16 compound treatment 0.261 0.0365 0.52 0.244 0.0301 0.51 0.727 0.9999 3063769 Maybridge4_002150 NNC(=O)c1ccc(CSc2ccc(cn2)C(F)(F)F)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B17 compound treatment 0.205 -0.0195 -0.28 0.213 -8.75E-4 -0.01 -0.2073 -0.7434 3178247 Maybridge4_002151 COC(=O)C1=C(CSC1)Nc2ccc(OC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B18 compound treatment 0.253 0.0285 0.41 0.261 0.0471 0.79 0.8479 0.9526 3063773 Maybridge4_002152 CC(C)(C)SC(=O)c1cccnc1SCCS(=O)(=O)c2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B19 compound treatment 0.226 0.00153 0.02 0.208 -0.00588 -0.1 -0.0542 -0.537 3178248 Maybridge4_002153 Cc1csc2sc(/C=N/Cc3cccs3)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B20 compound treatment 0.054 -0.17 -2.44 0.058 -0.156 -2.62 -3.5741 -0.9994 1206852 Maybridge4_002154 CCOC(=O)c1cnc2n(C)nc(C)c2c1Sc3nnc(SC)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B21 compound treatment 0.282 0.0575 0.82 0.277 0.0631 1.06 1.3311 0.9922 3178249 Maybridge4_002155 CS(=O)(=O)c1sc(C(=O)NC(=S)Nc2ccc(OC(F)(F)F)cc2)c3CCC=Cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B22 compound treatment 0.214 -0.0105 -0.15 0.218 0.00412 0.07 -0.0569 -0.3451 3178341 Maybridge4_002156 CCOC(=O)CC1Sc2ccccc2N=C1SCC(=O)Nc3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B23 mock treatment 0.24 0.0155 0.22 0.25 0.0361 0.61 0.5858 0.9072 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 B24 mock treatment 0.223 -0.00147 -0.02 0.2 -0.0139 -0.23 -0.1795 -0.7678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C01 compound treatment 0.255 0.0305 0.44 0.226 0.0121 0.2 0.4527 0.9396 3063777 Maybridge4_002157 CCN(CC)C(=S)NC(=S)c1ccc(C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C02 compound treatment 0.262 0.0375 0.54 0.254 0.0401 0.67 0.8558 0.9937 3178342 Maybridge4_002158 COC(=O)c1ccccc1S(=O)(=O)/C(=C/Nc2nc(C)cc(C)n2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C03 compound treatment 0.234 0.00953 0.14 0.291 0.0771 1.29 1.0117 0.7773 1199477 Maybridge4_002159 CN(C1CCS(=O)(=O)C1)C(=O)COc2ccc(Oc3ccccc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C04 compound treatment 0.246 0.0215 0.31 0.254 0.0401 0.67 0.694 0.9371 3178343 Maybridge4_002160 CSc1c(C#N)c(nn1C(=O)C(C)(C)C)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C05 compound treatment 0.275 0.0505 0.72 0.23 0.0161 0.27 0.7025 0.9102 3063778 Maybridge4_002161 CS/C(=N/C(=N)Nc1ccc(Cl)cc1)/N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C06 compound treatment 0.315 0.0905 1.29 0.291 0.0771 1.29 1.831 1.0 3178344 Maybridge4_002162 Cc1c(csc1C(=O)Nc2ccc(F)cc2F)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C07 compound treatment 0.254 0.0295 0.42 0.253 0.0391 0.66 0.763 0.9772 1368486 Maybridge4_002163 OC(=O)c1ccccc1SCC(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C08 compound treatment 0.277 0.0525 0.75 0.254 0.0401 0.67 1.0075 0.9985 3178345 Maybridge4_002164 CNC(=S)Nc1cscc1S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C09 compound treatment 0.202 -0.0225 -0.32 0.181 -0.0329 -0.55 -0.6174 -0.9669 3063810 Maybridge4_002165 Clc1cccc(NC(=S)NC(C#N)c2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C10 compound treatment 0.259 0.0345 0.49 0.195 -0.0189 -0.32 0.1252 0.2134 3178346 Maybridge4_002166 CN(C)/C=C/C(=O)c1cnc2cc(C)nn2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C11 compound treatment 0.307 0.0825 1.18 0.239 0.0251 0.42 1.1329 0.9038 1175106 Maybridge4_002167 Cc1c(nnc2cc(nn12)c3ccccc3)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C12 compound treatment 0.259 0.0345 0.49 0.226 0.0121 0.2 0.4932 0.9232 3178347 Maybridge4_002168 COC(=O)c1scc(c1n2cccc2)S(=O)(=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C13 compound treatment 0.227 0.00253 0.04 0.222 0.00812 0.14 0.122 0.8649 1474680 Maybridge4_002169 NC1=C(C#N)C(C(=C(O1)C2CC2)C#N)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C14 compound treatment 0.294 0.0695 0.99 0.193 -0.0209 -0.35 0.4555 0.432 1123050 Maybridge4_002170 CC(C)S(=O)(=O)c1cscc1NC(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C15 compound treatment 0.279 0.0545 0.78 0.235 0.0211 0.35 0.8023 0.9363 1443948 Maybridge4_002171 O=c1c2CSCc2[nH]c3cc(nn13)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C16 compound treatment 0.052 -0.172 -2.47 0.053 -0.161 -2.7 -3.6537 -0.999 3063812 Maybridge4_002172 CC(C)S(=O)(=O)c1csc(NC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C17 compound treatment 0.224 -4.69E-4 -0.01 0.19 -0.0239 -0.4 -0.2881 -0.7188 1153510 Maybridge4_002173 COc1c(Cl)scc1NC(=O)N2CC(C)OC(C)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C18 compound treatment 0.274 0.0495 0.71 0.26 0.0461 0.77 1.0484 0.999 3063813 Maybridge4_002174 CS(=O)(=O)c1scc(c1C#N)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C19 compound treatment 0.188 -0.0365 -0.52 0.168 -0.0459 -0.77 -0.9133 -0.982 3178348 Maybridge4_002175 CC(C)(C)c1ccc(cc1)c2n[nH]c(c2C#N)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C20 compound treatment 0.256 0.0315 0.45 0.271 0.0571 0.96 0.9969 0.9408 3178349 Maybridge4_002176 Cn1nc(cc1C(F)(F)F)c2ccc(s2)C(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C21 compound treatment 0.267 0.0425 0.61 0.235 0.0211 0.35 0.6809 0.967 3063814 Maybridge4_002177 COC(=O)c1sc(SC)c(C#N)c1c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C22 compound treatment 0.206 -0.0185 -0.26 0.218 0.00412 0.07 -0.1378 -0.5047 3178350 Maybridge4_002178 CCN(CCS(=O)(=O)c1ccc(C)cc1)C(=O)c2ccc(s2)c3cc(nn3C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C23 mock treatment 0.211 -0.0135 -0.19 0.199 -0.0149 -0.25 -0.3128 -0.9918 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 C24 mock treatment 0.208 -0.0165 -0.24 0.216 0.00212 0.04 -0.1413 -0.5933 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D01 compound treatment 0.271 0.0465 0.67 0.219 0.00512 0.09 0.5315 0.7919 3063815 Maybridge4_002179 Nc1nc(ncc1S(=O)(=O)Cc2ccco2)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D02 compound treatment 0.267 0.0425 0.61 0.282 0.0681 1.14 1.2387 0.9564 3063818 Maybridge4_002180 CC(C)(C)S(=O)(=O)c1cnc(nc1N)c2cnccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D03 compound treatment 0.254 0.0295 0.42 0.354 0.14 2.35 1.9617 0.821 3178351 Maybridge4_002181 Cc1csc2sc(COC(=O)Nc3ccccc3)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D04 compound treatment 0.249 0.0245 0.35 0.207 -0.00688 -0.12 0.1665 0.4508 3178352 Maybridge4_002182 CSc1sc(C(=O)NN)c2CCCC3(SCCS3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D05 compound treatment 0.313 0.0885 1.27 0.224 0.0101 0.17 1.0156 0.7949 3063851 Maybridge4_002183 CCOC(=O)c1sc(c2/C(=N\O)/CC(C)(C)Cc12)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D06 compound treatment 0.33 0.106 1.51 0.233 0.0191 0.32 1.2943 0.8387 3178353 Maybridge4_002184 Cc1ccc(cc1)S(=O)(=O)CCSc2sc(C#N)c3CC(C)(C)CC(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D07 compound treatment 0.286 0.0615 0.88 0.256 0.0421 0.71 1.1223 0.9941 1145089 Maybridge4_002185 CSc1sc(C(=O)O)c-2c1S(=O)(=O)N(C)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D08 compound treatment 0.277 0.0525 0.75 0.302 0.0881 1.48 1.5772 0.9507 3178354 Maybridge4_002186 FC(F)(F)c1cccc(c1)C(=O)C(=C2SCCCCS2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D09 compound treatment 0.331 0.107 1.52 0.237 0.0231 0.39 1.3519 0.8598 3063853 Maybridge4_002187 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D10 compound treatment 0.325 0.101 1.44 0.217 0.00312 0.05 1.0539 0.7324 3178355 Maybridge4_002188 CC1(C)CCc2cc(ccc2O1)c3ccn(n3)S(=O)(=O)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D11 compound treatment 0.2 -0.0245 -0.35 0.157 -0.0569 -0.95 -0.9225 -0.9073 3063854 Maybridge4_002189 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)Sc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D12 compound treatment 0.244 0.0195 0.28 0.241 0.0271 0.46 0.5195 0.9725 3178356 Maybridge4_002190 CC1(C)CCc2cc(ccc2O1)c3ccnc(S)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D13 compound treatment 0.302 0.0775 1.11 0.202 -0.0119 -0.2 0.6432 0.5709 3063856 Maybridge4_002191 Cc1c(Br)sc2sc(c(C)c12)c3nn(C)cc3Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D14 compound treatment 0.327 0.103 1.47 0.291 0.0771 1.29 1.9524 0.9981 3178357 Maybridge4_002192 CSc1sc(Cl)c2CC(C)(C)C/C(=N/O)/c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D15 compound treatment 0.319 0.0945 1.35 0.299 0.0851 1.43 1.9664 0.9996 3178358 Maybridge4_002193 CC(C)NC(=O)CSc1nccc(n1)c2sc3sc(Br)c(C)c3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D16 compound treatment 0.224 -4.69E-4 -0.01 0.22 0.00612 0.1 0.068 0.6596 3063857 Maybridge4_002194 Sc1nccc(n1)c2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D17 compound treatment 0.317 0.0925 1.32 0.319 0.105 1.76 2.1835 0.99 3063858 Maybridge4_002195 COc1ccc(CSc2nnc(CSc3cccs3)n2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D18 compound treatment 0.298 0.0735 1.05 0.212 -0.00188 -0.03 0.7215 0.6856 3178359 Maybridge4_002196 CS(=O)(=NS(=O)(=O)c1cccc2nsnc12)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D19 compound treatment 0.289 0.0645 0.92 0.268 0.0541 0.91 1.295 1.0 3178360 Maybridge4_002197 Cc1cc2ncc(c(C)n2n1)c3ccnc(SCCS(=O)(=O)c4ccccc4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D20 compound treatment 0.276 0.0515 0.74 0.21 -0.00388 -0.07 0.4752 0.6422 3063859 Maybridge4_002198 CC(C)C1Oc2c(cccc2N(CC(=O)O)C1=S)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D21 compound treatment 0.276 0.0515 0.74 0.277 0.0631 1.06 1.2704 0.9843 3178361 Maybridge4_002199 CSc1nc(nc(c1C#N)c2ccc(OC(F)(F)F)cc2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D22 compound treatment 0.302 0.0775 1.11 0.272 0.0581 0.98 1.474 0.998 1139728 Maybridge4_002200 CCOC(=O)CC1Sc2ccccc2N=C1SCCS(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D23 mock treatment 0.263 0.0385 0.55 0.235 0.0211 0.35 0.6404 0.9772 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 D24 mock treatment 0.187 -0.0375 -0.54 0.247 0.0331 0.56 0.0142 0.0183 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E01 compound treatment 0.227 0.00253 0.04 0.201 -0.0129 -0.22 -0.1272 -0.5805 1149948 Maybridge4_002201 Clc1ccc(cc1)N2CCN(CC2)C3=Cc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E02 compound treatment 0.268 0.0435 0.62 0.248 0.0341 0.57 0.8453 0.9991 3178362 Maybridge4_002202 COC(=O)c1ccccc1S(=O)(=O)/C(=C/Nc2nc(SC)nc(n2)C3CC3)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E03 compound treatment 0.309 0.0845 1.21 0.298 0.0841 1.41 1.8534 0.997 3063320 Maybridge4_002203 CSc1nc(N)n(n1)c2cc(Cl)cc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E04 compound treatment 0.21 -0.0145 -0.21 0.206 -0.00788 -0.13 -0.2398 -0.9765 3178363 Maybridge4_002204 CSc1n[nH]c(NC(=O)c2ccccc2Cl)c1S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E05 compound treatment 0.252 0.0275 0.39 0.224 0.0101 0.17 0.3986 0.9294 1032087 Maybridge4_002205 Oc1ccnc(SCc2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E06 compound treatment 0.304 0.0795 1.14 0.266 0.0521 0.87 1.423 0.9916 3178364 Maybridge4_002206 CN1c2ccccc2C(=O)/C(=C\Nc3ncccn3)/S1(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E07 compound treatment 0.276 0.0515 0.74 0.289 0.0751 1.26 1.4128 0.9673 3063324 Maybridge4_002207 CCN(CCC#N)C(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E08 compound treatment 0.264 0.0395 0.57 0.281 0.0671 1.13 1.1965 0.9492 1520456 Maybridge4_002208 CCOC(=O)NS(=O)(=O)c1ccccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E09 compound treatment 0.293 0.0685 0.98 0.289 0.0751 1.26 1.5847 0.9923 1248613 Maybridge4_002209 O=c1cc([nH]c2cc(nn12)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E10 compound treatment 0.309 0.0845 1.21 0.268 0.0541 0.91 1.4973 0.9901 3178365 Maybridge4_002210 Cc1cccc(c1)c2n[nH]c(c2C#N)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E11 compound treatment 0.285 0.0605 0.87 0.232 0.0181 0.3 0.8273 0.9015 1374930 Maybridge4_002211 COc1cccc(c1)c2c(nnc3cc(nn23)c4ccccc4)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E12 compound treatment 0.28 0.0555 0.79 0.254 0.0401 0.67 1.0379 0.9966 1289071 Maybridge4_002212 Clc1ccc(cc1)S(=O)(=O)CCSc2ccccc2NC(=O)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E13 compound treatment 0.169 -0.0555 -0.79 0.198 -0.0159 -0.27 -0.7494 -0.8954 1391332 Maybridge4_002213 COc1ccc(cc1)C2C(=C(N)OC(=C2C#N)C3CC3)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E14 compound treatment 0.255 0.0305 0.44 0.207 -0.00688 -0.12 0.2272 0.503 3063326 Maybridge4_002214 Cc1nccc(n1)c2cccc(NS(=O)(=O)c3ccccc3C(F)(F)F)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E15 compound treatment 0.275 0.0505 0.72 0.229 0.0151 0.25 0.6906 0.9015 3178456 Maybridge4_002215 Cn1nc(cc1N)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E16 compound treatment 0.273 0.0485 0.69 0.234 0.0201 0.34 0.7297 0.9452 1540260 Maybridge4_002216 CC(C)S(=O)(=O)c1csc(NC(=O)N2CCCCC2)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E17 compound treatment 0.286 0.0615 0.88 0.27 0.0561 0.94 1.2884 0.9994 1698879 Maybridge4_002217 Nc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E18 compound treatment 0.206 -0.0185 -0.26 0.171 -0.0429 -0.72 -0.6956 -0.9075 1598720 Maybridge4_002218 Clc1ccc(cc1)c2csc(S(=O)C3CCCCC3)c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E19 compound treatment 0.233 0.00853 0.12 0.206 -0.00788 -0.13 -0.0072 -0.0399 1438402 Maybridge4_002219 O=C(c1ccccc1)c2cnc3ccccn3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E20 compound treatment 0.188 -0.0365 -0.52 0.221 0.00712 0.12 -0.2843 -0.5312 3178457 Maybridge4_002220 CN(C)c1scc(c1C#N)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E21 compound treatment 0.218 -0.00647 -0.09 0.195 -0.0189 -0.32 -0.2894 -0.877 3178458 Maybridge4_002221 Cc1ccc(cc1)S(=O)(=O)/C(=C/Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E22 compound treatment 0.235 0.0105 0.15 0.239 0.0251 0.42 0.4047 0.9038 1367919 Maybridge4_002222 O=S(=O)(Cc1ccco1)Cc2nc(cs2)c3ccc(cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E23 mock treatment 0.234 0.00953 0.14 0.252 0.0381 0.64 0.5489 0.8389 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 E24 mock treatment 0.201 -0.0235 -0.34 0.183 -0.0309 -0.52 -0.6038 -0.9779 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F01 compound treatment 0.223 -0.00147 -0.02 0.217 0.00312 0.05 0.0222 0.3935 3063357 Maybridge4_002223 CNC(=O)c1cc(C#N)c(SC)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F02 compound treatment 0.282 0.0575 0.82 0.257 0.0431 0.72 1.0937 0.998 3178459 Maybridge4_002224 CSc1scc2CCc3cnc(SCC(=O)c4ccc(Cl)cc4)nc3-c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F03 compound treatment 0.288 0.0635 0.91 0.287 0.0731 1.23 1.5104 0.9891 3063358 Maybridge4_002225 Cc1csc2sc(C(=O)Oc3ccc(Cl)cc3)c(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F04 compound treatment 0.289 0.0645 0.92 0.278 0.0641 1.08 1.4137 0.9971 3178460 Maybridge4_002226 Nc1nc(ncc1S(=O)(=O)c2ccc(cn2)C(F)(F)F)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F05 compound treatment 0.308 0.0835 1.19 0.279 0.0651 1.09 1.6178 0.999 3063359 Maybridge4_002227 CSc1sc(cc1c2nc(C)cs2)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F06 compound treatment 0.356 0.132 1.88 0.235 0.0211 0.35 1.5811 0.8258 3178461 Maybridge4_002228 CC(C)S(=O)(=O)c1cscc1NC(=O)c2ccc(s2)c3cc(nn3C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F07 compound treatment 0.268 0.0435 0.62 0.235 0.0211 0.35 0.691 0.9644 1693988 Maybridge4_002229 CS(=O)(=O)c1sc(C(=O)Nc2ccccc2Cl)c3CCC=Cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F08 compound treatment 0.316 0.0915 1.31 0.291 0.0771 1.29 1.8411 1.0 3178462 Maybridge4_002230 CSc1sc(c2ccon2)c(c1C#N)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F09 compound treatment 0.205 -0.0195 -0.28 0.225 0.0111 0.19 -0.0649 -0.1935 3178463 Maybridge4_002231 CC1(C)CC(=O)C=C(SCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F10 compound treatment 0.368 0.144 2.05 0.307 0.0931 1.56 2.5569 0.9909 3063360 Maybridge4_002232 FC(F)(F)c1ccc(nc1)S(=O)(=O)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F11 compound treatment 0.315 0.0905 1.29 0.318 0.104 1.75 2.1514 0.9891 3178464 Maybridge4_002233 CS(=O)(=NS(=O)(=O)c1ccc(s1)c2ccccn2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F12 compound treatment 0.302 0.0775 1.11 0.259 0.0451 0.76 1.3197 0.9827 3063362 Maybridge4_002234 C/S(=N\C(=O)Nc1ccc(Cl)cc1)/c2sc(Cl)c3CCCC(=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F13 compound treatment 0.268 0.0435 0.62 0.314 0.1 1.68 1.6286 0.9087 3178465 Maybridge4_002235 CS(=O)(=NC(=S)NC(=O)Oc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F14 compound treatment 0.254 0.0295 0.42 0.197 -0.0169 -0.28 0.0984 0.1935 3063392 Maybridge4_002236 FC(F)(F)c1cnc(N2CCS(=NC(=O)c3ccccc3)CC2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F15 compound treatment 0.284 0.0595 0.85 0.229 0.0151 0.25 0.7816 0.8797 3178466 Maybridge4_002237 Cc1c(Br)sc2sc(c(C)c12)c3ccnc(SCC(=O)NCC=C)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F16 compound treatment 0.23 0.00553 0.08 0.291 0.0771 1.29 0.9713 0.7489 1201268 Maybridge4_002238 C(Sc1nccc(n1)c2ccc3OCCc3c2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F17 compound treatment 0.295 0.0705 1.01 0.329 0.115 1.93 2.0797 0.9541 1378146 Maybridge4_002239 CS(=O)(=O)c1sc(NC(=O)Nc2ccc(Cl)cc2)c3CCC=Cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F18 compound treatment 0.328 0.104 1.48 0.254 0.0401 0.67 1.5233 0.9364 1406686 Maybridge4_002240 Cc1nn(Cc2cccc(c2)C(=O)NC(=O)Nc3ccc(Cl)cc3)c(C)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F19 compound treatment 0.341 0.117 1.67 0.235 0.0211 0.35 1.4293 0.8388 1721379 Maybridge4_002241 O=S(=O)(N1CCCCC1)c2ccc(s2)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F20 compound treatment 0.205 -0.0195 -0.28 0.175 -0.0389 -0.65 -0.6583 -0.9279 3063394 Maybridge4_002242 CN(C)/C=C\1/C(=O)c2sccc2N(C)S1(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F21 compound treatment 0.3 0.0755 1.08 0.24 0.0261 0.44 1.074 0.9211 3178467 Maybridge4_002243 CSc1sc(c(C)c1c2ccnc(S)n2)c3nc(C)cs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F22 compound treatment 0.281 0.0565 0.81 0.275 0.0611 1.03 1.2972 0.9931 1422989 Maybridge4_002244 Clc1ccc(OC(=O)c2csc(n2)C3COc4ccccc4O3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F23 mock treatment 0.243 0.0185 0.27 0.211 -0.00288 -0.05 0.1533 0.569 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 F24 mock treatment 0.222 -0.00247 -0.04 0.194 -0.0199 -0.33 -0.2608 -0.7776 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G01 compound treatment 0.207 -0.0175 -0.25 0.186 -0.0279 -0.47 -0.5075 -0.9568 1651892 Maybridge4_002245 CCCCC1(Cc2ccccc2)C(=O)Nc3ccccc3C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G02 compound treatment 0.221 -0.00347 -0.05 0.209 -0.00488 -0.08 -0.0929 -0.9713 3178468 Maybridge4_002246 CSc1nc(N/C=C(\C#N)/S(=O)(=O)c2ccccc2Cl)nc(n1)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G03 compound treatment 0.231 0.00653 0.09 0.26 0.0461 0.77 0.6135 0.7867 3063398 Maybridge4_002247 CC(=N)NC(=S)Nc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G04 compound treatment 0.259 0.0345 0.49 0.254 0.0401 0.67 0.8255 0.9884 3178469 Maybridge4_002248 CSc1n[nH]c(NC(=O)Nc2ccccc2)c1S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G05 compound treatment 0.217 -0.00747 -0.11 0.247 0.0331 0.56 0.3176 0.561 3063400 Maybridge4_002249 CN(C)C(=O)Oc1ccnc(SCc2c(F)cccc2Cl)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G06 compound treatment 0.272 0.0475 0.68 0.252 0.0381 0.64 0.9332 0.9995 3178470 Maybridge4_002250 COc1ccc(cc1)c2n[nH]c(SC)c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G07 compound treatment 0.302 0.0775 1.11 0.275 0.0611 1.03 1.5096 0.9992 3063401 Maybridge4_002251 Cc1ccc(COc2ccc(I)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G08 compound treatment 0.323 0.0985 1.41 0.281 0.0671 1.13 1.7932 0.9938 3178471 Maybridge4_002252 CSc1sc(C(=O)Nc2cccc(Cl)c2)c(c1C#N)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G09 compound treatment 0.253 0.0285 0.41 0.285 0.0711 1.19 1.1327 0.8978 1687124 Maybridge4_002253 CCN(CCS(=O)(=O)c1ccccc1)S(=O)(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G10 compound treatment 0.296 0.0715 1.02 0.32 0.106 1.78 1.983 0.9654 3178472 Maybridge4_002254 COC(=O)c1scc(c1N)S(=O)(=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G11 compound treatment 0.32 0.0955 1.37 0.274 0.0601 1.01 1.6798 0.9889 1226475 Maybridge4_002255 NC(=O)c1nnc2cc(nn2c1N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G12 compound treatment 0.249 0.0245 0.35 0.209 -0.00488 -0.08 0.1903 0.5281 1452741 Maybridge4_002256 Clc1ccc(cc1)S(=O)(=O)CCSc2ccccc2NC(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G13 compound treatment 0.354 0.13 1.85 0.292 0.0781 1.31 2.2373 0.9857 3063431 Maybridge4_002257 Fc1cccc(Cl)c1CN/C(=C(\N=C\c2cccs2)/C#N)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G14 compound treatment 0.283 0.0585 0.84 0.278 0.0641 1.08 1.353 0.9923 3178473 Maybridge4_002258 Clc1cccc(Cl)c1CSc2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G15 compound treatment 0.209 -0.0155 -0.22 0.195 -0.0189 -0.32 -0.3805 -0.9846 3178474 Maybridge4_002259 COc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G16 compound treatment 0.066 -0.158 -2.27 0.057 -0.157 -2.63 -3.4646 -0.9972 1133071 Maybridge4_002260 CNC(=O)Nc1ccccc1NC2=C(CSC2)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G17 compound treatment 0.263 0.0385 0.55 0.302 0.0881 1.48 1.4356 0.9095 3178475 Maybridge4_002261 CC1CN(CC(C)O1)/C=C(\C#N)/S(=O)(=O)c2ccc(Br)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G18 compound treatment 0.337 0.113 1.61 0.259 0.0451 0.76 1.6737 0.9409 3063432 Maybridge4_002262 CS(=O)(=NS(=O)(=O)c1ccccc1C(F)(F)F)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G19 compound treatment 0.285 0.0605 0.87 0.245 0.0311 0.52 0.9816 0.9707 1259331 Maybridge4_002263 COCc1cc(O)nc2n(C)nc(c3cccs3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G20 compound treatment 0.239 0.0145 0.21 0.236 0.0221 0.37 0.4096 0.9624 3063433 Maybridge4_002264 CS/C(=C(/C#N)\S(=O)(=O)C(C)C)/N1CCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G21 compound treatment 0.251 0.0265 0.38 0.261 0.0471 0.79 0.8276 0.9434 3178476 Maybridge4_002265 CSc1c(C#N)c(nn1CC(=O)NN)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G22 compound treatment 0.235 0.0105 0.15 0.223 0.00912 0.15 0.2148 1.0 3063434 Maybridge4_002266 Cc1onc(c1C(=O)N=S(=O)(C)C)c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G23 mock treatment 0.253 0.0285 0.41 0.207 -0.00688 -0.12 0.207 0.488 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 G24 mock treatment 0.175 -0.0495 -0.71 0.181 -0.0329 -0.55 -0.8905 -0.9924 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H01 compound treatment 0.212 -0.0125 -0.18 0.214 1.25E-4 0.0 -0.1246 -0.6987 3178477 Maybridge4_002267 CCOC(=O)c1sc(SCc2ccccc2)c(c1n3cccc3)S(=O)(=O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H02 compound treatment 0.228 0.00353 0.05 0.228 0.0141 0.24 0.2034 0.8389 1259984 Maybridge4_002268 CSc1scc2CCc3cnc(SCC(=O)C(C)(C)C)nc3-c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H03 compound treatment 0.255 0.0305 0.44 0.253 0.0391 0.66 0.7731 0.9804 3063436 Maybridge4_002269 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H04 compound treatment 0.312 0.0875 1.25 0.246 0.0321 0.54 1.2666 0.9291 3178558 Maybridge4_002270 COC(=O)c1sc(SCCOC(=O)c2ccccc2Cl)c3C(=O)CC(C)(C)Cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H05 compound treatment 0.236 0.0115 0.16 0.263 0.0491 0.82 0.6996 0.8321 3063438 Maybridge4_002271 CSc1sc(C#N)c(C)c1c2ccn(n2)C(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H06 compound treatment 0.25 0.0255 0.37 0.294 0.0801 1.34 1.2092 0.8677 3178559 Maybridge4_002272 CSc1sc(C(=O)/C=C/N(C)C)c(c1C#N)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H07 compound treatment 0.052 -0.172 -2.47 0.046 -0.168 -2.82 -3.7367 -0.9978 1222048 Maybridge4_002273 CS(=O)c1sc(C(=O)OCc2ccccc2)c3CC(C)(C)CC(=O)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H08 compound treatment 0.254 0.0295 0.42 0.311 0.0971 1.63 1.4514 0.8619 3178560 Maybridge4_002274 CSc1sc(c2cc[nH]n2)c(c1C#N)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H09 compound treatment 0.204 -0.0205 -0.29 0.243 0.0291 0.49 0.1386 0.2433 3178561 Maybridge4_002275 CC1(C)CC(=O)C=C(SCc2c(Cl)cccc2Cl)S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H10 compound treatment 0.323 0.0985 1.41 0.284 0.0701 1.18 1.8288 0.996 1307156 Maybridge4_002276 CC1(C)CCc2cc(ccc2O1)c3ccn(n3)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H11 compound treatment 0.29 0.0655 0.94 0.329 0.115 1.93 2.0291 0.9448 3063440 Maybridge4_002277 CSc1nnc(c2ccc(s2)S(=O)(=O)n3nc(C)cc3C)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H12 compound treatment 0.248 0.0235 0.34 0.255 0.0411 0.69 0.7261 0.9455 3178562 Maybridge4_002278 CCSc1nccc(n1)c2ccc3OC(C)(C)CCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H13 compound treatment 0.338 0.114 1.62 0.319 0.105 1.76 2.3959 0.9991 3063442 Maybridge4_002279 Cc1csc2sc(c(C)c12)c3ccnc(SCc4ccccc4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H14 compound treatment 0.245 0.0205 0.29 0.263 0.0491 0.82 0.7907 0.9034 3178563 Maybridge4_002280 CCOC(=O)c1sc(/S(=N/C(=O)Nc2ccccc2Cl)/C)c3C=CCCc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H15 compound treatment 0.319 0.0945 1.35 0.329 0.115 1.93 2.3224 0.9848 1505800 Maybridge4_002281 COC(=O)C(CC(C)C)NS(=O)(=O)c1ccc(s1)c2nnc(SC)n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H16 compound treatment 0.295 0.0705 1.01 0.258 0.0441 0.74 1.237 0.9884 3178564 Maybridge4_002282 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCSc2ncccc2C(=O)NCc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H17 compound treatment 0.318 0.0935 1.34 0.328 0.114 1.92 2.3004 0.9846 3178565 Maybridge4_002283 Clc1ccc(cc1)C2CC(=O)C=C(SCC(=O)c3ccccc3)S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H18 compound treatment 0.292 0.0675 0.97 0.299 0.0851 1.43 1.6933 0.9818 3063443 Maybridge4_002284 C/C(=N\O)/c1ccc2OCCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H19 compound treatment 0.28 0.0555 0.79 0.303 0.0891 1.5 1.6194 0.9561 3063445 Maybridge4_002285 CC1(C)CC(=O)c2c(SCC(=O)NN)sc(C#N)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H20 compound treatment 0.305 0.0805 1.15 0.248 0.0341 0.57 1.2195 0.948 1254429 Maybridge4_002286 Cc1nn(C)c2ncc(C(=O)N)c(Oc3cccnc3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H21 compound treatment 0.275 0.0505 0.72 0.242 0.0281 0.47 0.8449 0.9787 3063446 Maybridge4_002287 CCOC(=O)c1sc(SC)c2c1CCCC32SCCS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H22 compound treatment 0.228 0.00353 0.05 0.271 0.0571 0.96 0.7137 0.7433 1921420 Maybridge4_002288 OC(=O)/C=C/1\OC(=O)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H23 mock treatment 0.243 0.0185 0.27 0.232 0.0181 0.3 0.4025 0.9976 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 H24 mock treatment 0.214 -0.0105 -0.15 0.18 -0.0339 -0.57 -0.5079 -0.8639 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I01 compound treatment 0.229 0.00453 0.06 0.225 0.0111 0.19 0.1779 0.8999 3178566 Maybridge4_002289 Cc1ccc(cc1)C(=O)OC[C@H]2O[C@@H](C[C@@H]2OC(=O)c3ccc(C)cc3)c4nnc5ncccn45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I02 compound treatment 0.216 -0.00847 -0.12 0.241 0.0271 0.46 0.2363 0.5015 3178567 Maybridge4_002290 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)Cc2ccc(Cl)cc2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I03 compound treatment 0.236 0.0115 0.16 0.248 0.0341 0.57 0.5216 0.8752 3063447 Maybridge4_002291 CCOC(=O)c1c(C)noc1c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I04 compound treatment 0.287 0.0625 0.89 0.308 0.0941 1.58 1.7495 0.9637 3064096 Maybridge4_002292 CSc1sc(NC(=O)N2CCOCC2)c(c1C#N)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I05 compound treatment 0.285 0.0605 0.87 0.268 0.0541 0.91 1.2546 0.9997 3064097 Maybridge4_002293 CCOC(=O)/C=C/1\NC(=O)CS1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I06 compound treatment 0.12 -0.104 -1.49 0.152 -0.0619 -1.04 -1.791 -0.9842 3064098 Maybridge4_002294 CSc1[nH]nc(c1C#N)c2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I07 compound treatment 0.321 0.0965 1.38 0.261 0.0471 0.79 1.5356 0.965 3064099 Maybridge4_002295 Fc1ccc(NC(=S)N(CCC#N)CC2CCCO2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I08 compound treatment 0.315 0.0905 1.29 0.275 0.0611 1.03 1.6411 0.9933 3064100 Maybridge4_002296 CSc1sc(C(=O)O)c(C)c1S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I09 compound treatment 0.314 0.0895 1.28 0.307 0.0931 1.56 2.0108 0.9951 1242964 Maybridge4_002297 Cc1nn(c(NC(=O)c2ccccc2)c1C#N)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I10 compound treatment 0.297 0.0725 1.04 0.294 0.0801 1.34 1.6845 0.9918 3064101 Maybridge4_002298 CC(C)(C)S(=O)(=O)/C(=C/Nc1ccccn1)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I11 compound treatment 0.297 0.0725 1.04 0.294 0.0801 1.34 1.6845 0.9918 1003716 Maybridge4_002299 Cc1ccc(cc1)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I12 compound treatment 0.306 0.0815 1.17 0.225 0.0111 0.19 0.9567 0.81 3064102 Maybridge4_002300 COC(=O)c1scc(c1/N=C/N(C)C)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I13 compound treatment 0.304 0.0795 1.14 0.22 0.00612 0.1 0.8771 0.7679 3178568 Maybridge4_002301 COc1cccc(c1)C(=O)/C=c/2\[nH]c(=O)\c(=C/c3cccs3)\s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I14 compound treatment 0.313 0.0885 1.27 0.316 0.102 1.71 2.1075 0.9889 1621333 Maybridge4_002302 Cc1nccc(n1)c2cccc(NC(=O)Nc3ccccc3)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I15 compound treatment 0.236 0.0115 0.16 0.189 -0.0249 -0.42 -0.1786 -0.3978 1156135 Maybridge4_002303 CC(C)(C)c1ccc(cc1)c2n[nH]c(NS(=O)(=O)c3ccccc3)c2Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I16 compound treatment 0.268 0.0435 0.62 0.29 0.0761 1.28 1.3437 0.9454 3064103 Maybridge4_002304 COC(=O)c1sc(SC)c(C#N)c1c2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I17 compound treatment 0.244 0.0195 0.28 0.21 -0.00388 -0.07 0.1516 0.5284 1665125 Maybridge4_002305 O=C(Nc1ccccc1)Nc2ccc(cc2)C3SCCS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I18 compound treatment 0.254 0.0295 0.42 0.232 0.0181 0.3 0.5138 0.987 3064104 Maybridge4_002306 O=S(=O)(C(=C1SCCCS1)C#N)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I19 compound treatment 0.252 0.0275 0.39 0.253 0.0391 0.66 0.7428 0.9701 3178569 Maybridge4_002307 CSc1nc2cc(C)nn2c(c1C#N)c3ccc(cc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I20 compound treatment 0.275 0.0505 0.72 0.252 0.0381 0.64 0.9636 0.9982 3178570 Maybridge4_002308 Cc1ccc(cc1)S(=O)(=NC(=O)NC(=O)c2c(Cl)cccc2Cl)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I21 compound treatment 0.211 -0.0135 -0.19 0.199 -0.0149 -0.25 -0.3128 -0.9918 3064105 Maybridge4_002309 CSc1nc(C)nc(N/C=C(\C#N)/S(=O)(=O)c2ccc(C)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I22 compound treatment 0.199 -0.0255 -0.36 0.235 0.0211 0.35 -0.0069 -0.0135 1118314 Maybridge4_002310 NNC(=O)c1csc(CS(=O)(=O)Cc2ccco2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I23 mock treatment 0.216 -0.00847 -0.12 0.21 -0.00388 -0.07 -0.1316 -0.9575 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 I24 mock treatment 0.223 -0.00147 -0.02 0.174 -0.0399 -0.67 -0.4881 -0.7289 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J01 compound treatment 0.177 -0.0475 -0.68 0.183 -0.0309 -0.52 -0.8465 -0.9911 3064106 Maybridge4_002311 CSc1sc(c2n[nH]cc2Br)c3CC(C)(C)CC(=O)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J02 compound treatment 0.306 0.0815 1.17 0.215 0.00112 0.02 0.838 0.7185 3178571 Maybridge4_002312 CSc1scc2CCc3cnc(SCC(=O)NCC=C)nc3-c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J03 compound treatment 0.217 -0.00747 -0.11 0.231 0.0171 0.29 0.1277 0.4165 3064107 Maybridge4_002313 CSc1sc(C#N)c2CC(CC(=O)c12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J04 compound treatment 0.238 0.0135 0.19 0.241 0.0271 0.46 0.4588 0.9274 3178572 Maybridge4_002314 NC(=S)c1cnn2c(cc(nc12)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J05 compound treatment 0.335 0.111 1.58 0.294 0.0801 1.34 2.0689 0.9968 3064108 Maybridge4_002315 COC(=O)c1sccc1N/C=C(\C#N)/S(=O)(=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J06 compound treatment 0.277 0.0525 0.75 0.253 0.0391 0.66 0.9957 0.9977 3178573 Maybridge4_002316 CCOC(=O)c1sc(SC)c-2c1CCc3conc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J07 compound treatment 0.263 0.0385 0.55 0.24 0.0261 0.44 0.6998 0.9936 3178574 Maybridge4_002317 Cc1nn(Cc2nnc(o2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c(C)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J08 compound treatment 0.312 0.0875 1.25 0.294 0.0801 1.34 1.8362 0.9994 3064109 Maybridge4_002318 CCCS(=O)(=O)/C(=C/c1sccc1Oc2ccccc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J09 compound treatment 0.312 0.0875 1.25 0.325 0.111 1.87 2.2042 0.9812 3178575 Maybridge4_002319 Cc1ccc(cc1)S(=O)(=O)CCSC2=CC(=O)CC(C)(C)S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J10 compound treatment 0.302 0.0775 1.11 0.281 0.0671 1.13 1.5808 1.0 3064110 Maybridge4_002320 Clc1ccc(cc1)c2ccnc(SCCS(=O)(=O)c3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J11 compound treatment 0.278 0.0535 0.77 0.238 0.0241 0.4 0.8277 0.9556 3178576 Maybridge4_002321 CSc1sc(C(=O)Sc2ccccc2)c-3c1S(=O)(=O)N(C)c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J12 compound treatment 0.32 0.0955 1.37 0.276 0.0621 1.04 1.7035 0.9911 1454764 Maybridge4_002322 CCOC(=O)C1=C(Nc2ccc(OC(=O)C)cc2)C(=O)N(C1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J13 compound treatment 0.326 0.102 1.45 0.274 0.0601 1.01 1.7405 0.9842 3178577 Maybridge4_002323 Cc1csc2sc(c(C)c12)c3ccnc(SCC(=O)c4ccccc4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J14 compound treatment 0.227 0.00253 0.04 0.247 0.0331 0.56 0.4187 0.7516 3178578 Maybridge4_002324 CCOC(=O)c1sc(/S(=N/S(=O)(=O)c2cccc(Cl)c2)/C)c3C=CCCc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J15 compound treatment 0.285 0.0605 0.87 0.274 0.0601 1.01 1.3258 0.9971 3064111 Maybridge4_002325 COc1cccc(NC(=S)N=S(=O)(C)c2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J16 compound treatment 0.327 0.103 1.47 0.285 0.0711 1.19 1.8811 0.9948 3178579 Maybridge4_002326 CCCCc1ccc(NC(=O)N=S2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J17 compound treatment 0.321 0.0965 1.38 0.333 0.119 2.0 2.3901 0.9837 3064112 Maybridge4_002327 Cc1nn(Cc2nnc(SCc3c(Cl)cccc3Cl)o2)c(C)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J18 compound treatment 0.281 0.0565 0.81 0.268 0.0541 0.91 1.2141 0.9983 3178580 Maybridge4_002328 C/S(=N/C(=O)Nc1ccc(Cl)cc1)/c2ccc(OC(=O)c3ccc(Cl)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J19 compound treatment 0.366 0.142 2.02 0.267 0.0531 0.89 2.062 0.9321 3064113 Maybridge4_002329 CS(=O)(=NS(=O)(=O)c1cc(cs1)S(=O)(=O)c2ccccc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J20 compound treatment 0.342 0.118 1.68 0.281 0.0671 1.13 1.9854 0.9811 1183286 Maybridge4_002330 CN1c2ccsc2-c3nc(SCc4ccc(Cl)cc4)ncc3S1(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J21 compound treatment 0.297 0.0725 1.04 0.263 0.0491 0.82 1.3166 0.9935 3064114 Maybridge4_002331 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)CCSc2ccc(cn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J22 compound treatment 0.266 0.0415 0.59 0.25 0.0361 0.61 0.8488 0.9999 3178581 Maybridge4_002332 O=C(CCN1CCC(=N1)c2cccs2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J23 mock treatment 0.206 -0.0185 -0.26 0.245 0.0311 0.52 0.1826 0.3119 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 J24 mock treatment 0.209 -0.0155 -0.22 0.212 -0.00188 -0.03 -0.1787 -0.7996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K01 compound treatment 0.239 0.0145 0.21 0.234 0.0201 0.34 0.3858 0.9728 3064115 Maybridge4_002333 C/C(=C\C#N)/Nc1c(C)n(C)n(c2ccccc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K02 compound treatment 0.242 0.0175 0.25 0.219 0.00512 0.09 0.2381 0.8983 3178657 Maybridge4_002334 CSc1sc(C(=O)O)c(c1C#N)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K03 compound treatment 0.198 -0.0265 -0.38 0.237 0.0231 0.39 0.0067 0.0124 1629094 Maybridge4_002335 NC(=S)NN1C2CSC1CS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K04 compound treatment 0.219 -0.00547 -0.08 0.284 0.0701 1.18 0.7769 0.6587 3178658 Maybridge4_002336 CSc1c(C#N)c(nn1C(=O)c2cccs2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K05 compound treatment 0.268 0.0435 0.62 0.297 0.0831 1.4 1.4268 0.9339 3178659 Maybridge4_002337 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCCN3C2c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K06 compound treatment 0.269 0.0445 0.64 0.234 0.0201 0.34 0.6892 0.956 3064116 Maybridge4_002338 CSc1nc(/N=C/N(C)C)n2nc(cc2n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K07 compound treatment 0.234 0.00953 0.14 0.258 0.0441 0.74 0.6201 0.8234 3178660 Maybridge4_002339 CN(CCC#N)C(=S)Nc1ccc(F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K08 compound treatment 0.31 0.0855 1.22 0.264 0.0501 0.84 1.46 0.9833 3064117 Maybridge4_002340 COC(=O)c1scc(C#N)c1/N=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K09 compound treatment 0.284 0.0595 0.85 0.303 0.0891 1.5 1.6599 0.9643 1197958 Maybridge4_002341 CCN(CCS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K10 compound treatment 0.251 0.0265 0.38 0.276 0.0621 1.04 1.0056 0.9063 1372972 Maybridge4_002342 COc1ncccc1C(=O)Nc2ccc(F)cc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K11 compound treatment 0.314 0.0895 1.28 0.288 0.0741 1.24 1.7853 0.9999 3178661 Maybridge4_002343 CC(=O)Nc1c(Br)c(nn1c2ccccc2)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K12 compound treatment 0.254 0.0295 0.42 0.237 0.0231 0.39 0.5731 0.9991 3064118 Maybridge4_002344 O=S(=O)(/C(=C/c1ccc(\C=C(/C#N)\S(=O)(=O)c2ccccc2)cc1)/C#N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K13 compound treatment 0.285 0.0605 0.87 0.234 0.0201 0.34 0.8511 0.9157 3178662 Maybridge4_002345 Oc1c2CN(C3CCCCC3)C(=O)c2nc4cc(nn14)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K14 compound treatment 0.275 0.0505 0.72 0.301 0.0871 1.46 1.5451 0.9472 1503351 Maybridge4_002346 CNC(=O)Nc1cccc(c1)c2ccnc(C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K15 compound treatment 0.164 -0.0605 -0.86 0.181 -0.0329 -0.55 -1.0018 -0.9764 3178663 Maybridge4_002347 Clc1ccc(cc1)S(=O)(=O)/C(=C/c2ccccc2Cl)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K16 compound treatment 0.254 0.0295 0.42 0.25 0.0361 0.61 0.7274 0.9844 1326810 Maybridge4_002348 CC(C)S(=O)(=O)c1cnc(nc1N)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K17 compound treatment 0.241 0.0165 0.24 0.229 0.0151 0.25 0.3467 0.9994 3064119 Maybridge4_002349 CNC(=O)Nc1ccc(cc1)C2SCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K18 compound treatment 0.307 0.0825 1.18 0.219 0.00512 0.09 0.8956 0.7566 1218060 Maybridge4_002350 CCOC(=O)c1cnc2c(csc2c1Sc3ccc(Cl)cc3)S(=O)(=O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K19 compound treatment 0.28 0.0555 0.79 0.258 0.0441 0.74 1.0853 0.9994 3064120 Maybridge4_002351 CSc1nc2cc(C)nn2c(c3ccco3)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K20 compound treatment 0.288 0.0635 0.91 0.262 0.0481 0.81 1.2137 0.9983 1209169 Maybridge4_002352 CS(=O)N(C(=O)c1scc(c1C)S(=O)(=O)c2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K21 compound treatment 0.259 0.0345 0.49 0.247 0.0331 0.56 0.7424 0.9983 1134325 Maybridge4_002353 COCc1cc(OC(=O)N(C)C)nc2n(C)nc(c3cccs3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K22 compound treatment 0.252 0.0275 0.39 0.228 0.0141 0.24 0.4461 0.9705 1310626 Maybridge4_002354 CCOC(=O)CSc1sc(C(=O)OCC)c-2c1S(=O)(=O)N(C)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K23 mock treatment 0.206 -0.0185 -0.26 0.231 0.0171 0.29 0.0164 0.0421 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 K24 mock treatment 0.198 -0.0265 -0.38 0.199 -0.0149 -0.25 -0.4442 -0.9796 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L01 compound treatment 0.196 -0.0285 -0.41 0.215 0.00112 0.02 -0.2746 -0.6736 3064121 Maybridge4_002355 CSc1sc(c2ccn(n2)C(=O)Nc3ccccc3)c4CC(C)(C)CC(=O)c14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L02 compound treatment 0.193 -0.0315 -0.45 0.13 -0.0839 -1.41 -1.3137 -0.8889 3178664 Maybridge4_002356 CS(=O)(=N/C=C(\C#N)/S(=O)(=O)c1ccc(cn1)C(F)(F)F)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L03 compound treatment 0.259 0.0345 0.49 0.216 0.00212 0.04 0.3745 0.7562 3064122 Maybridge4_002357 CSc1sc(C#N)c(C)c1C(=O)/C=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L04 compound treatment 0.202 -0.0225 -0.32 0.231 0.0171 0.29 -0.024 -0.0557 3178665 Maybridge4_002358 CCOC(=O)c1sc(SCCS(=O)(=O)c2ccc(Cl)cc2)c3C(=O)CCCc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L05 compound treatment 0.273 0.0485 0.69 0.259 0.0451 0.76 1.0264 0.9991 1438715 Maybridge4_002359 Cc1c(C=C)c(sc1C(=O)Oc2ccccc2)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L06 compound treatment 0.284 0.0595 0.85 0.22 0.00612 0.1 0.6748 0.7868 3178666 Maybridge4_002360 CC1(C)CC(=O)c2c(SCCOC(=O)c3ccccc3Cl)sc(C#N)c2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L07 compound treatment 0.225 5.31E-4 0.01 0.282 0.0681 1.14 0.8139 0.7118 3064123 Maybridge4_002361 Cc1nn(Cc2nc(cs2)C(C)(C)C)c(C)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L08 compound treatment 0.24 0.0155 0.22 0.239 0.0251 0.42 0.4553 0.9552 1009905 Maybridge4_002362 CC(=O)Nc1ccc(Br)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L09 compound treatment 0.231 0.00653 0.09 0.241 0.0271 0.46 0.388 0.8348 3178667 Maybridge4_002363 CSc1sc(c2CCCC(=O)c12)c3ccnc(SCC(=O)c4ccc(Cl)cc4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L10 compound treatment 0.249 0.0245 0.35 0.224 0.0101 0.17 0.3683 0.9446 3064124 Maybridge4_002364 O=S1(=O)CC=C(C1)Sc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L11 compound treatment 0.304 0.0795 1.14 0.265 0.0511 0.86 1.4112 0.9903 3178668 Maybridge4_002365 Cc1cc(C)n(CCS(=O)(=O)c2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L12 compound treatment 0.282 0.0575 0.82 0.298 0.0841 1.41 1.5803 0.967 3064125 Maybridge4_002366 Clc1ccc(cc1)C(=O)Nc2cc(cs2)S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L13 compound treatment 0.246 0.0215 0.31 0.275 0.0611 1.03 0.9432 0.8806 3178669 Maybridge4_002367 Cc1csc2sc(c(C)c12)c3ccnc(SCC(=O)NCc4ccccc4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L14 compound treatment 0.261 0.0365 0.52 0.241 0.0271 0.46 0.6914 0.9976 1344584 Maybridge4_002368 COC(=O)c1c(C)n2CSCc2c1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L15 compound treatment 0.237 0.0125 0.18 0.241 0.0271 0.46 0.4487 0.917 3178670 Maybridge4_002369 CN(C)/C=C/C(=O)c1ccsc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L16 compound treatment 0.258 0.0335 0.48 0.277 0.0631 1.06 1.0883 0.9358 1542795 Maybridge4_002370 CCCCc1ccc(NC(=O)N=S2CCN(CC2)C(=O)c3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L17 compound treatment 0.216 -0.00847 -0.12 0.214 1.25E-4 0.0 -0.0842 -0.6948 1463535 Maybridge4_002371 CN1c2sc(C)c(C)c2C(=C(C(=O)Nc3ccc(Cl)cc3)S1(=O)=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L18 compound treatment 0.235 0.0105 0.15 0.268 0.0541 0.91 0.7489 0.8133 1537505 Maybridge4_002372 Cc1occc1C(=O)C(=C(NCc2cccnc2)NCc3cccnc3)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L19 compound treatment 0.263 0.0385 0.55 0.244 0.0301 0.51 0.7472 0.9991 3064207 Maybridge4_002373 CS(=O)(=O)c1cc2cc(Cl)ccc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L20 compound treatment 0.22 -0.00447 -0.06 0.232 0.0181 0.3 0.1699 0.5466 3064208 Maybridge4_002374 FC(F)(F)c1ccc(SC(=O)c2csc(n2)C3COc4ccccc4O3)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L21 compound treatment 0.28 0.0555 0.79 0.253 0.0391 0.66 1.026 0.9955 3064209 Maybridge4_002375 CN(C)/C=N/C(=O)c1sc(c2C=CCCc12)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L22 compound treatment 0.296 0.0715 1.02 0.233 0.0191 0.32 0.9505 0.8864 1320320 Maybridge4_002376 O=C(C1Cc2ccccc2C1)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L23 mock treatment 0.263 0.0385 0.55 0.233 0.0191 0.32 0.6167 0.9669 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 L24 mock treatment 0.191 -0.0335 -0.48 0.205 -0.00888 -0.15 -0.4438 -0.8853 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M01 compound treatment 0.267 0.0425 0.61 0.245 0.0311 0.52 0.7996 0.9971 3064210 Maybridge4_002377 OC(=O)c1ccc2ccccc2c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M02 compound treatment 0.247 0.0225 0.32 0.246 0.0321 0.54 0.6091 0.9697 3064211 Maybridge4_002378 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2cccc(Cl)c2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M03 compound treatment 0.272 0.0475 0.68 0.298 0.0841 1.41 1.4791 0.9439 3178671 Maybridge4_002379 COC(=O)c1ccc(Oc2ccc(Cl)cc2Cl)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M04 compound treatment 0.245 0.0205 0.29 0.265 0.0511 0.86 0.8144 0.898 3178672 Maybridge4_002380 CCOC(=O)/C(=C\Nc1ccc(F)c(Cl)c1)/S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M05 compound treatment 0.048 -0.176 -2.52 0.045 -0.169 -2.83 -3.7891 -0.9983 3064212 Maybridge4_002381 Clc1ccc(/C=C/C(=O)Nc2cccc(Cl)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M06 compound treatment 0.275 0.0505 0.72 0.268 0.0541 0.91 1.1534 0.9936 3064213 Maybridge4_002382 NNC(=O)CS(=O)(=O)c1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M07 compound treatment 0.162 -0.0625 -0.89 0.097 -0.117 -1.96 -2.0189 -0.9366 3178673 Maybridge4_002383 Cc1cc(C)cc(NC(=S)Nc2cc(C)cc(C)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M08 compound treatment 0.233 0.00853 0.12 0.217 0.00312 0.05 0.1234 0.9289 3178674 Maybridge4_002384 Clc1ccc(SCC(=O)Nc2cscc2S(=O)(=O)c3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M09 compound treatment 0.29 0.0655 0.94 0.304 0.0901 1.51 1.7324 0.9735 1165743 Maybridge4_002385 CCN(CCS(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M10 compound treatment 0.256 0.0315 0.45 0.277 0.0631 1.06 1.0681 0.9276 3178675 Maybridge4_002386 Clc1ccccc1NC(=S)Nc2cscc2S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M11 compound treatment 0.267 0.0425 0.61 0.235 0.0211 0.35 0.6809 0.967 1302916 Maybridge4_002387 CC(C)(C)n1nc(cc1NC(=O)Nc2ccccc2)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M12 compound treatment 0.275 0.0505 0.72 0.263 0.0491 0.82 1.0941 0.9978 3178676 Maybridge4_002388 COC(=O)c1sc(SC)c(c1C)c2ccn(n2)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M13 compound treatment 0.282 0.0575 0.82 0.22 0.00612 0.1 0.6546 0.7893 3064215 Maybridge4_002389 COc1c(Cl)scc1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M14 compound treatment 0.284 0.0595 0.85 0.24 0.0261 0.44 0.9122 0.9524 3178677 Maybridge4_002390 CC(C)S(=O)(=O)c1csc(C(=O)NN)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M15 compound treatment 0.196 -0.0285 -0.41 0.183 -0.0309 -0.52 -0.6544 -0.9929 1619049 Maybridge4_002391 CC(C)(C)c1ccc(cc1)c2[nH]nc(NC(=O)c3ccccc3Cl)c2Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M16 compound treatment 0.235 0.0105 0.15 0.233 0.0191 0.32 0.3335 0.9405 3178678 Maybridge4_002392 CSc1sc(C(=O)O)c(I)c1S(=O)(=O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M17 compound treatment 0.325 0.101 1.44 0.273 0.0591 0.99 1.7185 0.9836 3178679 Maybridge4_002393 CC(C)(C)c1ccc(cc1)C(=O)C(=C2SCCCS2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M18 compound treatment 0.237 0.0125 0.18 0.277 0.0631 1.06 0.8759 0.8152 3064216 Maybridge4_002394 CS(=O)(=NC(=O)Nc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M19 compound treatment 0.25 0.0255 0.37 0.258 0.0441 0.74 0.7819 0.9469 3178680 Maybridge4_002395 CSc1nc2cc(C)nn2c(c1C#N)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M20 compound treatment 0.301 0.0765 1.09 0.253 0.0391 0.66 1.2384 0.9701 1447748 Maybridge4_002396 Clc1ccccc1c2csc(CS(=O)(=O)c3cccs3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M21 compound treatment 0.29 0.0655 0.94 0.269 0.0551 0.93 1.317 1.0 3178681 Maybridge4_002397 CSc1nc(N)n2nc(cc2n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M22 compound treatment 0.286 0.0615 0.88 0.219 0.00512 0.09 0.6832 0.7725 3178753 Maybridge4_002398 CN(C)/C=C/C(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)CC(C)(C)Cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M23 mock treatment 0.266 0.0415 0.59 0.223 0.00912 0.15 0.5284 0.8612 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 M24 mock treatment 0.264 0.0395 0.57 0.21 -0.00388 -0.07 0.3538 0.6217 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N01 compound treatment 0.266 0.0415 0.59 0.253 0.0391 0.66 0.8844 0.9987 3064217 Maybridge4_002399 CCOC(=O)c1sc2sc(C(=O)OCC)c(c3ccc(Cl)cc3)c2c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N02 compound treatment 0.256 0.0315 0.45 0.261 0.0471 0.79 0.8782 0.9645 3064244 Maybridge4_002400 CCOC(=O)NS(=O)(=O)c1ccc(s1)c2cc(n(C)n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N03 compound treatment 0.216 -0.00847 -0.12 0.263 0.0491 0.82 0.4974 0.5968 3064245 Maybridge4_002401 CSc1scc2CC(C)(C)CC(=O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N04 compound treatment 0.226 0.00153 0.02 0.228 0.0141 0.24 0.1831 0.7692 3064246 Maybridge4_002402 CC1(C)CCc2cc(ccc2O1)C3SCCS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N05 compound treatment 0.266 0.0415 0.59 0.265 0.0511 0.86 1.0268 0.9839 3064248 Maybridge4_002403 Cc1nn(CC(=S)N)c(C)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N06 compound treatment 0.25 0.0255 0.37 0.229 0.0151 0.25 0.4377 0.9842 1138975 Maybridge4_002404 CC(C)S(=O)(=O)c1cscc1N2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N07 compound treatment 0.246 0.0215 0.31 0.228 0.0141 0.24 0.3854 0.9916 3064249 Maybridge4_002405 Fc1cccc(NC(=S)N(CCS(=O)(=O)c2ccc(Cl)cc2)Cc3cccs3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N08 compound treatment 0.254 0.0295 0.42 0.262 0.0481 0.81 0.8698 0.9543 3064250 Maybridge4_002406 Clc1ccc(C(=O)C2C(=O)CCC(C2=O)c3ccccc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N09 compound treatment 0.244 0.0195 0.28 0.263 0.0491 0.82 0.7806 0.8966 3064251 Maybridge4_002407 CSc1sc(c2CC(C)(C)CC(=O)c12)c3ccnc(SCC(=O)C(C)(C)C)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N10 compound treatment 0.268 0.0435 0.62 0.221 0.00712 0.12 0.5248 0.8278 1318871 Maybridge4_002408 Cn1ccnc1SCCS(=O)(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N11 compound treatment 0.252 0.0275 0.39 0.25 0.0361 0.61 0.7072 0.9782 1250473 Maybridge4_002409 CCOC(=O)c1sc(SCc2ccccc2)c3c1-c4sccc4N(C)S3(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N12 compound treatment 0.244 0.0195 0.28 0.271 0.0571 0.96 0.8755 0.8767 3064253 Maybridge4_002410 FC(F)(F)c1cc(cc(c1)S(=O)(=O)/N=S\2/CCC3(C2)OCCO3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N13 compound treatment 0.272 0.0475 0.68 0.256 0.0421 0.71 0.9807 0.9998 1662782 Maybridge4_002411 CSc1sc(c2nc(cs2)C(C)(C)C)c3CCCC(=O)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N14 compound treatment 0.252 0.0275 0.39 0.234 0.0201 0.34 0.5173 0.9971 1607185 Maybridge4_002412 Clc1ccc(cc1)C(=O)N=S2CCN(CC2)C(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N15 compound treatment 0.288 0.0635 0.91 0.224 0.0101 0.17 0.7627 0.825 3178754 Maybridge4_002413 COC(=O)C1=C(CSC1)Nc2ccc(OC(=O)c3cccc(c3)C(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N16 compound treatment 0.23 0.00553 0.08 0.281 0.0671 1.13 0.8526 0.7549 1495489 Maybridge4_002414 Clc1ccc(OC(=O)c2cccnc2SCCS(=O)(=O)c3ccccc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N17 compound treatment 0.255 0.0305 0.44 0.184 -0.0299 -0.5 -0.0458 -0.0688 3178755 Maybridge4_002415 CSc1sc(C(=O)NN)c2CCC=Cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N18 compound treatment 0.284 0.0595 0.85 0.218 0.00412 0.07 0.6511 0.7621 3178756 Maybridge4_002416 CS(=O)(=NS(=O)(=O)c1cccs1)c2ccc(OC(=O)c3ccc(Cl)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N19 compound treatment 0.237 0.0125 0.18 0.272 0.0581 0.98 0.8166 0.8232 3064254 Maybridge4_002417 CS(=O)(=O)/C(=C/Nc1cnccn1)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N20 compound treatment 0.299 0.0745 1.07 0.263 0.0491 0.82 1.3368 0.9919 1627111 Maybridge4_002418 O=C(SCc1cccs1)c2csc(n2)C3COc4ccccc4O3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N21 compound treatment 0.319 0.0945 1.35 0.313 0.0991 1.66 2.1325 0.9947 3064255 Maybridge4_002419 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)CCN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N22 compound treatment 0.247 0.0225 0.32 0.211 -0.00288 -0.05 0.1938 0.5946 3178757 Maybridge4_002420 Clc1ccc(cc1)c2cc(NC(=O)C3Cc4ccccc4C3)[nH]n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N23 mock treatment 0.263 0.0385 0.55 0.229 0.0151 0.25 0.5692 0.9381 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 N24 mock treatment 0.23 0.00553 0.08 0.225 0.0111 0.19 0.188 0.9269 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O01 compound treatment 0.215 -0.00947 -0.14 0.227 0.0131 0.22 0.06 0.232 1259648 Maybridge4_002421 COc1ccc(NC(=O)C(C(=O)Nc2ccc(OC)cc2)C3(CC4CC5CC(C4)C3)C5)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O02 compound treatment 0.218 -0.00647 -0.09 0.223 0.00912 0.15 0.0429 0.2396 3064256 Maybridge4_002422 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)c2ccccn2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O03 compound treatment 0.223 -0.00147 -0.02 0.242 0.0281 0.47 0.3189 0.675 1743228 Maybridge4_002423 Cc1ccc(Nc2cc(O)nn2C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O04 compound treatment 0.259 0.0345 0.49 0.242 0.0281 0.47 0.683 0.9997 3064257 Maybridge4_002424 CCn1c(S)nc2ccccc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O05 compound treatment 0.284 0.0595 0.85 0.269 0.0551 0.93 1.2563 0.9991 3178758 Maybridge4_002425 Cc1c(C)c(C)c(CSc2ccccc2N)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O06 compound treatment 0.239 0.0145 0.21 0.232 0.0181 0.3 0.3621 0.9828 3064258 Maybridge4_002426 CS/C(=C(\C#N)/C(=O)C1CC1)/N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O07 compound treatment 0.221 -0.00347 -0.05 0.237 0.0231 0.39 0.2394 0.6117 1286597 Maybridge4_002427 O=S(=O)(CCN1CCSCC1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O08 compound treatment 0.236 0.0115 0.16 0.203 -0.0109 -0.18 -0.0124 -0.0505 3064259 Maybridge4_002428 Clc1ccccc1C(=O)Nc2cscc2S(=O)(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O09 compound treatment 0.237 0.0125 0.18 0.208 -0.00588 -0.1 0.057 0.2787 3178759 Maybridge4_002429 O=S(=O)(CCSc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O10 compound treatment 0.226 0.00153 0.02 0.183 -0.0309 -0.52 -0.3509 -0.6766 1558086 Maybridge4_002430 COC(=O)C1=C(CSC1)Nc2ccc(F)cc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O11 compound treatment 0.204 -0.0205 -0.29 0.221 0.00712 0.12 -0.1225 -0.3872 3064260 Maybridge4_002431 Cc1cc(C)n2nc(cc2n1)c3ccc(cc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O12 compound treatment 0.202 -0.0225 -0.32 0.233 0.0191 0.32 -3.0E-4 -6.0E-4 3178760 Maybridge4_002432 CC(C)S(=O)(=O)c1csc(C(=O)OCC(=O)c2ccc(Cl)cc2)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O13 compound treatment 0.198 -0.0265 -0.38 0.216 0.00212 0.04 -0.2425 -0.6377 3064262 Maybridge4_002433 Clc1ccc(cc1)S(=O)(=O)/C(=C/N2CCCCC2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O14 compound treatment 0.237 0.0125 0.18 0.219 0.00512 0.09 0.1876 0.9434 3178761 Maybridge4_002434 Fc1ccc(NC(=O)c2cccnc2Sc3cccs3)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O15 compound treatment 0.296 0.0715 1.02 0.246 0.0321 0.54 1.1047 0.9552 3064263 Maybridge4_002435 Nc1nc(Sc2ccc(Cl)cc2)c(C#N)c(c1C#N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O16 compound treatment 0.25 0.0255 0.37 0.235 0.0211 0.35 0.5089 0.9999 3178762 Maybridge4_002436 CSc1scc(c1C#N)c2cc(Cl)cc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O17 compound treatment 0.214 -0.0105 -0.15 0.229 0.0151 0.25 0.0736 0.2498 3064280 Maybridge4_002437 O=C(C(=C1SCCCS1)C#N)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O18 compound treatment 0.237 0.0125 0.18 0.232 0.0181 0.3 0.3419 0.9682 3064281 Maybridge4_002438 CN(/N=C(\C#N)/C(=O)C1CC1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O19 compound treatment 0.246 0.0215 0.31 0.212 -0.00188 -0.03 0.1955 0.6316 1358615 Maybridge4_002439 COCc1cc(OC(=O)N(C)C)nc2n(C)nc(C)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O20 compound treatment 0.203 -0.0215 -0.31 0.224 0.0101 0.17 -0.097 -0.2763 1379175 Maybridge4_002440 Cn1ccc(n1)c2cccc(NC(=O)Nc3ccccc3)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O21 compound treatment 0.256 0.0315 0.45 0.271 0.0571 0.96 0.9969 0.9408 3064282 Maybridge4_002441 CSc1c(C#N)c(nn1CNC(=O)Nc2ccccc2C(F)(F)F)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O22 compound treatment 0.231 0.00653 0.09 0.233 0.0191 0.32 0.293 0.8765 3064283 Maybridge4_002442 CCOC(=O)c1sc(SCc2c(Cl)cccc2Cl)c(c1N)S(=O)(=O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O23 mock treatment 0.241 0.0165 0.24 0.214 1.25E-4 0.0 0.1687 0.7134 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 O24 mock treatment 0.23 0.00553 0.08 0.193 -0.0209 -0.35 -0.1918 -0.534 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P01 compound treatment 0.25 0.0255 0.37 0.266 0.0521 0.87 0.8769 0.9249 3064285 Maybridge4_002443 Nc1c(C#N)sc2sc(C#N)c(c3ccco3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P02 compound treatment 0.219 -0.00547 -0.08 0.218 0.00412 0.07 -0.0064 -0.0608 3064286 Maybridge4_002444 CC(C)(C)c1ncc(c(N)n1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P03 compound treatment 0.246 0.0215 0.31 0.239 0.0251 0.42 0.516 0.9881 3178763 Maybridge4_002445 CCOC(=O)c1sc(SC)c2C(=O)CC(Cc12)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P04 compound treatment 0.224 -4.69E-4 -0.01 0.247 0.0331 0.56 0.3884 0.6985 3178764 Maybridge4_002446 CCOC(=O)c1sc(Sc2ccc(cn2)C(F)(F)F)c3C(=O)CC(C)(C)Cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P05 compound treatment 0.238 0.0135 0.19 0.25 0.0361 0.61 0.5656 0.8886 1299033 Maybridge4_002447 CS(=O)(=O)c1sc(C(=O)O)c2CCC=Cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P06 compound treatment 0.255 0.0305 0.44 0.247 0.0331 0.56 0.7019 0.9929 1436320 Maybridge4_002448 Cc1cc(C)n(n1)c2ncc(c(N)n2)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P07 compound treatment 0.245 0.0205 0.29 0.257 0.0431 0.72 0.7195 0.9211 3178765 Maybridge4_002449 CSc1scc2CCc3cn(nc3-c12)C(=O)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P08 compound treatment 0.264 0.0395 0.57 0.223 0.00912 0.15 0.5081 0.8674 3178766 Maybridge4_002450 CS(=O)(=NC(=O)NC(=O)c1ccc(Cl)cc1)c2ccc(cn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P09 compound treatment 0.243 0.0185 0.27 0.241 0.0271 0.46 0.5094 0.9669 3064288 Maybridge4_002451 O=S(=O)(N1CCCCC1)c2ccc(s2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P10 compound treatment 0.225 5.31E-4 0.01 0.225 0.0111 0.19 0.1374 0.7353 3064289 Maybridge4_002452 COC(=O)c1cnc(S)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P11 compound treatment 0.135 -0.0895 -1.28 0.153 -0.0609 -1.02 -1.6274 -0.9938 3178767 Maybridge4_002453 FC(F)(F)c1cc(NC(=S)NC(=O)Oc2ccccc2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P12 compound treatment 0.258 0.0335 0.48 0.235 0.0211 0.35 0.5899 0.9889 3064290 Maybridge4_002454 Cc1ccc(SCC(=O)c2ccc(CC(=O)O)s2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P13 compound treatment 0.339 0.115 1.64 0.26 0.0461 0.77 1.7058 0.9414 3178768 Maybridge4_002455 CS(=O)(=NS(=O)(=O)c1ccc(OC(F)(F)F)cc1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P14 compound treatment 0.209 -0.0155 -0.22 0.209 -0.00488 -0.08 -0.2143 -0.9085 3064291 Maybridge4_002456 CN(C)/C=C/C(=O)c1ccc2OCCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P15 compound treatment 0.26 0.0355 0.51 0.196 -0.0179 -0.3 0.1472 0.2495 3178769 Maybridge4_002457 Cc1cc2ncc(c(C)n2n1)c3ccnc(SCc4c(Cl)cccc4Cl)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P16 compound treatment 0.22 -0.00447 -0.06 0.201 -0.0129 -0.22 -0.198 -0.8786 3064292 Maybridge4_002458 CS(=O)(=O)CCSc1ncccc1C(=O)NCc2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P17 compound treatment 0.254 0.0295 0.42 0.24 0.0261 0.44 0.6087 0.9998 1476633 Maybridge4_002459 CCOC(=O)c1sc(N2CCCCC2)c3C(=O)CC(C)(C)Cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P18 compound treatment 0.224 -4.69E-4 -0.01 0.219 0.00512 0.09 0.0561 0.65 3064293 Maybridge4_002460 OC(=O)C1Cc2ccccc2C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P19 compound treatment 0.153 -0.0715 -1.02 0.138 -0.0759 -1.27 -1.6233 -0.9941 3178770 Maybridge4_002461 FC(F)(F)c1ccc(nc1)S(=O)(=O)/C(=C/Nc2cnccn2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P20 compound treatment 0.268 0.0435 0.62 0.238 0.0241 0.4 0.7266 0.9783 1356891 Maybridge4_002462 CCOC(=O)CC1Sc2ccccc2N=C1SCC(=O)Nc3ccc(Cl)cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P21 compound treatment 0.264 0.0395 0.57 0.287 0.0731 1.23 1.2677 0.9381 3064294 Maybridge4_002463 Clc1ccc(Sc2ccc(s2)c3ccccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P22 compound treatment 0.24 0.0155 0.22 0.277 0.0631 1.06 0.9063 0.8372 1623679 Maybridge4_002464 Cc1ccc(NC(=O)c2ccc3OCCc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P23 mock treatment 0.227 0.00253 0.04 0.238 0.0241 0.4 0.3119 0.7673 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2055 P24 mock treatment 0.203 -0.0215 -0.31 0.199 -0.0149 -0.25 -0.3937 -0.9947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A01 compound treatment 0.238 0.0125 0.18 0.239 0.0112 0.19 0.2593 0.9996 3178771 Maybridge4_002465 FC(F)(F)c1ccc(NC(=O)c2ccc3OCCc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A02 compound treatment 0.23 0.00447 0.06 0.214 -0.0138 -0.23 -0.1184 -0.4932 3178772 Maybridge4_002466 COc1cc(nc2ccc(C)c(NC(=O)Nc3ccc(OC(F)(F)F)cc3)c12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A03 compound treatment 0.282 0.0565 0.81 0.252 0.0242 0.41 0.8586 0.9495 1345781 Maybridge4_002467 O=C1N(CC2COc3ccccc3O2)C(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A04 compound treatment 0.211 -0.0145 -0.21 0.264 0.0362 0.61 0.2829 0.4403 1377469 Maybridge4_002468 CN(C)CC#Cc1cncc(c1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A05 compound treatment 0.213 -0.0125 -0.18 0.239 0.0112 0.19 0.0064 0.0246 1734397 Maybridge4_002469 Brc1cc2CCOc2c(c1)C(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A06 compound treatment 0.267 0.0415 0.59 0.19 -0.0378 -0.63 -0.029 -0.0334 3178773 Maybridge4_002470 FC(F)(F)c1ccc2cc(CSc3ccc(Cl)cc3)ccc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A07 compound treatment 0.236 0.0105 0.15 0.233 0.00522 0.09 0.1678 0.9674 3064295 Maybridge4_002471 COc1ccc(OC(=O)c2csc(COc3ccc4nonc4c3)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A08 compound treatment 0.253 0.0275 0.39 0.244 0.0162 0.27 0.4703 0.9839 1124957 Maybridge4_002472 Fc1ccc(cc1)S(=O)(=O)CCN2CCC(CC2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A09 compound treatment 0.256 0.0305 0.44 0.21 -0.0178 -0.3 0.0971 0.1839 3064326 Maybridge4_002473 Cc1nn(Cc2ccc(o2)C(=O)Sc3ccc(cn3)C(F)(F)F)c(C)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A10 compound treatment 0.213 -0.0125 -0.18 0.209 -0.0188 -0.32 -0.3496 -0.9642 1618157 Maybridge4_002474 CCOC(=O)c1c(SC)nc2ccc(Cl)cc2c1N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A11 compound treatment 0.222 -0.00353 -0.05 0.202 -0.0258 -0.43 -0.3417 -0.7843 1711585 Maybridge4_002475 CCOC(=O)NC(=O)c1cn(Cc2cccs2)c(=O)n(C)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A12 compound treatment 0.245 0.0195 0.28 0.238 0.0102 0.17 0.3182 0.9729 3064327 Maybridge4_002476 FC(F)(F)c1cc(N2CCN(CC2)C(=O)c3cccs3)c4ccccc4n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A13 compound treatment 0.252 0.0265 0.38 0.225 -0.00278 -0.05 0.2347 0.6153 3064329 Maybridge4_002477 Cc1ccc(cc1)S(=O)(=O)NCCSc2cc(nc3ccccc23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A14 compound treatment 0.266 0.0405 0.58 0.221 -0.00678 -0.11 0.3288 0.5574 3064330 Maybridge4_002478 Clc1ccc(NC(=O)OCC#Cc2ccc(C#N)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A15 compound treatment 0.262 0.0365 0.52 0.222 -0.00578 -0.1 0.3002 0.5659 3064331 Maybridge4_002479 COC(=O)c1scc2c(SCc3ccccc3)cc(nc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A16 compound treatment 0.24 0.0145 0.21 0.21 -0.0178 -0.3 -0.0647 -0.1781 3178850 Maybridge4_002480 CCCNC(=O)Nc1ccc(OC(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A17 compound treatment 0.248 0.0225 0.32 0.22 -0.00778 -0.13 0.1349 0.3889 1220133 Maybridge4_002481 COC(=O)c1sccc1n2cc(C#N)c(=O)n(C)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A18 compound treatment 0.211 -0.0145 -0.21 0.22 -0.00778 -0.13 -0.2393 -0.9749 1288518 Maybridge4_002482 O=c1[nH]nc(CSc2ccccn2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A19 compound treatment 0.219 -0.00653 -0.09 0.208 -0.0198 -0.33 -0.3008 -0.8722 1196923 Maybridge4_002483 Cn1c(=O)c(cn(c2ccccc2)c1=O)C(=S)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A20 compound treatment 0.248 0.0225 0.32 0.194 -0.0338 -0.57 -0.1737 -0.2665 3178851 Maybridge4_002484 COc1ccc(NC(=O)N(Cc2ccccc2)C(=O)CC#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A21 compound treatment 0.217 -0.00853 -0.12 0.223 -0.00478 -0.08 -0.143 -0.9793 1562266 Maybridge4_002485 Clc1ccccc1C(=O)CSC2=NCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A22 compound treatment 0.195 -0.0305 -0.44 0.214 -0.0138 -0.23 -0.4724 -0.9558 3064332 Maybridge4_002486 FC(F)(F)c1cc(Oc2ccc(Cl)cc2)c3cc(Cl)ccc3n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A23 mock treatment 0.205 -0.0205 -0.29 0.229 0.00122 0.02 -0.1932 -0.6563 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 A24 mock treatment 0.21 -0.0155 -0.22 0.208 -0.0198 -0.33 -0.3919 -0.9809 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B01 compound treatment 0.28 0.0545 0.78 0.296 0.0682 1.14 1.3605 0.9824 1234192 Maybridge4_002487 Cc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)C3COc4ccccc4O3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B02 compound treatment 0.247 0.0215 0.31 0.217 -0.0108 -0.18 0.0892 0.2502 3064333 Maybridge4_002488 COC(=O)c1cc2cc(Br)ccc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B03 compound treatment 0.246 0.0205 0.29 0.233 0.00522 0.09 0.269 0.8801 1523364 Maybridge4_002489 Cc1ccccc1NC(=O)NCCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B04 compound treatment 0.254 0.0285 0.41 0.25 0.0222 0.37 0.5516 0.999 3064334 Maybridge4_002490 Cc1c(sc2ccc(Cl)cc12)C(=O)COC(=O)c3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B05 compound treatment 0.255 0.0295 0.42 0.252 0.0242 0.41 0.5855 0.9998 3178852 Maybridge4_002491 Cc1cccc(C)c1NC(=O)N(Cc2ccccc2)C(=O)CC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B06 compound treatment 0.264 0.0385 0.55 0.237 0.00922 0.15 0.4985 0.8721 3064335 Maybridge4_002492 Cc1c(sc2ccccc12)c3ccnn3C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B07 compound treatment 0.262 0.0365 0.52 0.266 0.0382 0.64 0.8224 0.9947 1235231 Maybridge4_002493 COC(=O)c1ccc(CN(C(=O)C)C(=O)Nc2ccc(cc2C)C(=O)OC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B08 compound treatment 0.267 0.0415 0.59 0.242 0.0142 0.24 0.5882 0.9199 3178853 Maybridge4_002494 Clc1ccccc1NC(=S)N2CCOC2c3c[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B09 compound treatment 0.264 0.0385 0.55 0.249 0.0212 0.36 0.6409 0.9778 3064336 Maybridge4_002495 C=CCn1c(SCc2ccccc2)nnc1c3ccc4ncccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B10 compound treatment 0.069 -0.157 -2.24 0.062 -0.166 -2.78 -3.5507 -0.9942 3064337 Maybridge4_002496 O=C(CCSc1ccccc1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B11 compound treatment 0.278 0.0525 0.75 0.275 0.0472 0.79 1.0911 0.9996 3178854 Maybridge4_002497 CC(C)n1c(nc2cc(ccc12)C(=O)Nc3ccc(Cl)cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B12 compound treatment 0.251 0.0255 0.36 0.235 0.00722 0.12 0.3433 0.8941 1241391 Maybridge4_002498 Clc1cccc(NC(=O)OC2CCCCc3cccnc23)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B13 compound treatment 0.243 0.0175 0.25 0.219 -0.00878 -0.15 0.0725 0.2498 1376937 Maybridge4_002499 CCc1ccc2[nH]c(cc2c1)C(=O)NCCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B14 compound treatment 0.269 0.0435 0.62 0.24 0.0122 0.21 0.5847 0.893 3178855 Maybridge4_002500 FC(F)(F)COc1ccc(Sc2ncccn2)c(OCC(F)(F)F)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B15 compound treatment 0.252 0.0265 0.38 0.247 0.0192 0.32 0.4958 0.9968 1581778 Maybridge4_002501 Clc1ccc(cc1)c2ccc(s2)C(=O)NC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B16 compound treatment 0.251 0.0255 0.36 0.241 0.0132 0.22 0.4145 0.9717 1626834 Maybridge4_002502 C(N1CCC(=N1)c2ccco2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B17 compound treatment 0.252 0.0265 0.38 0.268 0.0402 0.68 0.745 0.9626 3064338 Maybridge4_002503 O=C(NC(=S)NCc1ccccc1)/C=C/c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B18 compound treatment 0.249 0.0235 0.34 0.228 2.19E-4 0.0 0.24 0.7148 3178856 Maybridge4_002504 OCCn1nc(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B19 compound treatment 0.234 0.00847 0.12 0.23 0.00222 0.04 0.112 0.8837 1406037 Maybridge4_002505 COc1ccc(cc1)c2csc(n2)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B20 compound treatment 0.221 -0.00453 -0.06 0.247 0.0192 0.32 0.1823 0.554 1528457 Maybridge4_002506 COc1ccc(cc1)c2nn(CCC#N)c(=O)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B21 compound treatment 0.246 0.0205 0.29 0.244 0.0162 0.27 0.3995 0.9993 3064339 Maybridge4_002507 Cc1ccc(CC(=O)c2cccnc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B22 compound treatment 0.24 0.0145 0.21 0.267 0.0392 0.66 0.6118 0.8866 3178857 Maybridge4_002508 CCOC(=O)NC(=S)N1C(C)CCCC1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B23 mock treatment 0.246 0.0205 0.29 0.229 0.00122 0.02 0.2215 0.7547 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 B24 mock treatment 0.238 0.0125 0.18 0.211 -0.0168 -0.28 -0.073 -0.2191 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C01 compound treatment 0.223 -0.00253 -0.04 0.219 -0.00878 -0.15 -0.1298 -0.8554 3178858 Maybridge4_002509 Cn1c(S)nnc1C2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C02 compound treatment 0.233 0.00747 0.11 0.245 0.0172 0.29 0.2799 0.9084 3064341 Maybridge4_002510 CCOC(=O)c1cncc(C#CCOC(=O)Nc2cc(Cl)cc(Cl)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C03 compound treatment 0.322 0.0965 1.38 0.264 0.0362 0.61 1.4056 0.9322 1514783 Maybridge4_002511 Clc1ccc(cc1)C(=O)NCC2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C04 compound treatment 0.239 0.0135 0.19 0.273 0.0452 0.76 0.6729 0.8593 3064342 Maybridge4_002512 CSc1nn(cc1c2nc(cs2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C05 compound treatment 0.302 0.0765 1.09 0.256 0.0282 0.47 1.1083 0.9299 3064366 Maybridge4_002513 COc1cccn(CC(=O)NN)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C06 compound treatment 0.302 0.0765 1.09 0.297 0.0692 1.16 1.5949 0.9995 3064367 Maybridge4_002514 Clc1ccc(Cl)c(c1)S(=O)(=O)n2ccc(n2)c3ccc(Br)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C07 compound treatment 0.285 0.0595 0.85 0.229 0.00122 0.02 0.6159 0.7239 1600605 Maybridge4_002515 Clc1ccc(NC(=O)c2csc(COc3ccc4nonc4c3)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C08 compound treatment 0.215 -0.0105 -0.15 0.255 0.0272 0.46 0.2165 0.4501 1505462 Maybridge4_002516 Cc1ccc(cc1)S(=O)(=O)CCN2CCC(CC2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C09 compound treatment 0.255 0.0295 0.42 0.183 -0.0448 -0.75 -0.2334 -0.2709 3064368 Maybridge4_002517 CSc1nc2ccc(NS(=O)(=O)c3ccccc3C(F)(F)F)cc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C10 compound treatment 0.253 0.0275 0.39 0.218 -0.00978 -0.16 0.1617 0.3798 3064369 Maybridge4_002518 CCOC(=O)c1c(SC)nc2c(cccc2c1N3CCCC3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C11 compound treatment 0.247 0.0215 0.31 0.226 -0.00178 -0.03 0.196 0.6353 3064371 Maybridge4_002519 Cn1c(S)nnc1CSc2cc(nc3ccccc23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C12 compound treatment 0.211 -0.0145 -0.21 0.238 0.0102 0.17 -0.0257 -0.0954 3064373 Maybridge4_002520 FC(F)(F)c1cccc(c1)N2C(=O)C3SCCN3C2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C13 compound treatment 0.274 0.0485 0.69 0.216 -0.0118 -0.2 0.3504 0.486 3178859 Maybridge4_002521 O=C(Nc1ccccc1)OCC#Cc2ccc(s2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C14 compound treatment 0.238 0.0125 0.18 0.223 -0.00478 -0.08 0.0694 0.3547 3064374 Maybridge4_002522 FC(F)(F)Oc1ccc(NC(=O)OCC#Cc2ccc(C#N)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C15 compound treatment 0.255 0.0295 0.42 0.266 0.0382 0.64 0.7516 0.9793 1566879 Maybridge4_002523 CCOC(=O)Cn1c(=O)c(cn(C(C)C)c1=O)c2nc(cs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C16 compound treatment 0.138 -0.0875 -1.25 0.13 -0.0978 -1.64 -2.0458 -0.9911 1528772 Maybridge4_002524 Cc1ccc(OC(=O)c2c(nnc3ccccc23)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C17 compound treatment 0.25 0.0245 0.35 0.224 -0.00378 -0.06 0.2026 0.5696 1617239 Maybridge4_002525 Clc1ccc(Cn2ccnc2COC(=O)Nc3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C18 compound treatment 0.251 0.0255 0.36 0.256 0.0282 0.47 0.5925 0.9916 1164357 Maybridge4_002526 COC(=O)CSCc1n[nH]c(=O)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C19 compound treatment 0.214 -0.0115 -0.16 0.254 0.0262 0.44 0.1945 0.414 3178860 Maybridge4_002527 Cn1c(=O)c(cn(c2ccccc2)c1=O)/C(=N/O)/N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C20 compound treatment 0.218 -0.00753 -0.11 0.247 0.0192 0.32 0.1519 0.4467 3178861 Maybridge4_002528 Fc1cccc(NC(=O)N(Cc2ccccc2)C(=O)CC#N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C21 compound treatment 0.27 0.0445 0.64 0.222 -0.00578 -0.1 0.3812 0.5924 1734152 Maybridge4_002529 CC(C)(C)OC(=O)N1CCN(CCNC(=O)c2ccc(Cl)cc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C22 compound treatment 0.2 -0.0255 -0.37 0.217 -0.0108 -0.18 -0.3862 -0.9475 1710452 Maybridge4_002530 COc1ccc(NC(=O)Nc2ccc(OC)c(OC3CCCC3)c2)cc1OC4CCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C23 mock treatment 0.222 -0.00353 -0.05 0.245 0.0172 0.29 0.1686 0.5748 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 C24 mock treatment 0.213 -0.0125 -0.18 0.228 2.19E-4 0.0 -0.1241 -0.6925 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D01 compound treatment 0.25 0.0245 0.35 0.278 0.0502 0.84 0.8435 0.9242 3064376 Maybridge4_002531 Cc1ccccc1NC(=O)N(Cc2cccs2)C(=O)CC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D02 compound treatment 0.212 -0.0135 -0.19 0.211 -0.0168 -0.28 -0.336 -0.9832 3178862 Maybridge4_002532 Cc1nc2ccc(NS(=O)(=O)c3ccccc3C(F)(F)F)cc2o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D03 compound treatment 0.213 -0.0125 -0.18 0.197 -0.0308 -0.52 -0.4921 -0.8998 3064377 Maybridge4_002533 FC(F)(F)c1cccc(NC(=S)Nc2cc(n[nH]2)c3cccs3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D04 compound treatment 0.333 0.107 1.54 0.274 0.0462 0.78 1.6355 0.9498 3178863 Maybridge4_002534 Cc1nc(cs1)c2sc3ccc(Cl)cc3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D05 compound treatment 0.218 -0.00753 -0.11 0.315 0.0872 1.46 0.9589 0.6533 1387292 Maybridge4_002535 CCCOc1cc(ccc1OC)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D06 compound treatment 0.276 0.0505 0.72 0.316 0.0882 1.48 1.5574 0.9455 3064378 Maybridge4_002536 Cc1c(sc2ccccc12)c3ccnn3C(=O)c4ccc(cc4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D07 compound treatment 0.3 0.0745 1.07 0.227 -7.81E-4 -0.01 0.7439 0.6983 1130276 Maybridge4_002537 CSc1ccccc1CNC(=O)NC2(CC3CC4CC(C3)C2)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D08 compound treatment 0.076 -0.15 -2.14 0.076 -0.152 -2.55 -3.3137 -0.9962 3064379 Maybridge4_002538 FC(F)(F)c1ccc(CSc2nccc(n2)c3cccnc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D09 compound treatment 0.268 0.0425 0.61 0.266 0.0382 0.64 0.8831 0.9996 3178864 Maybridge4_002539 CCOC(=O)CSc1nnc(c2ccc3ncccc3c2)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D10 compound treatment 0.321 0.0955 1.37 0.271 0.0432 0.73 1.4785 0.9562 3178865 Maybridge4_002540 Cc1c(sc2ccccc12)C(=S)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D11 compound treatment 0.258 0.0325 0.46 0.234 0.00622 0.1 0.4022 0.8449 3064380 Maybridge4_002541 CC(C)n1c(nc2cc(ccc12)C(=O)N3CCOCC3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D12 compound treatment 0.248 0.0225 0.32 0.259 0.0312 0.52 0.5978 0.9725 1150832 Maybridge4_002542 Nc1nccc(n1)c2ccc(NC(=O)Nc3ccccc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D13 compound treatment 0.308 0.0825 1.18 0.296 0.0682 1.14 1.6437 0.9999 3064381 Maybridge4_002543 CCc1ccc2[nH]c(cc2c1)C(=O)Nc3ccc(c(C#N)c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D14 compound treatment 0.289 0.0635 0.91 0.314 0.0862 1.45 1.6652 0.9748 3178947 Maybridge4_002544 FC(F)(F)COc1ccc(SCc2ccccc2)c(OCC(F)(F)F)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D15 compound treatment 0.238 0.0125 0.18 0.32 0.0922 1.55 1.2206 0.7834 1264919 Maybridge4_002545 CC(C)(C)c1ccc(s1)C(=O)OCc2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D16 compound treatment 0.275 0.0495 0.71 0.241 0.0132 0.22 0.6572 0.8863 3064382 Maybridge4_002546 CN1CCC(=N1)/C=C/c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D17 compound treatment 0.347 0.121 1.74 0.249 0.0212 0.36 1.4804 0.8347 3178948 Maybridge4_002547 O=C(NC(=S)N1CCCCC1)/C=C/c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D18 compound treatment 0.293 0.0675 0.97 0.271 0.0432 0.73 1.1953 0.9901 3064383 Maybridge4_002548 Cn1nc(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D19 compound treatment 0.289 0.0635 0.91 0.208 -0.0198 -0.33 0.4072 0.4212 1464348 Maybridge4_002549 COc1ccc(cc1)C(=O)CSC2=NCCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D20 compound treatment 0.272 0.0465 0.66 0.282 0.0542 0.91 1.1135 0.9881 3064384 Maybridge4_002550 CC(C)(C)C(=O)NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D21 compound treatment 0.302 0.0765 1.09 0.232 0.00422 0.07 0.8235 0.7513 3178949 Maybridge4_002551 O=C(Cc1cccc(Oc2ccccc2)c1)c3cccc(C#N)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D22 compound treatment 0.298 0.0725 1.04 0.282 0.0542 0.91 1.3764 0.9979 3064385 Maybridge4_002552 CC1CCCC(C)N1c2nn(C)c(=O)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D23 mock treatment 0.258 0.0325 0.46 0.239 0.0112 0.19 0.4615 0.921 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 D24 mock treatment 0.225 -5.31E-4 -0.01 0.243 0.0152 0.26 0.1752 0.6858 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E01 compound treatment 0.255 0.0295 0.42 0.251 0.0232 0.39 0.5736 0.9992 3064421 Maybridge4_002553 Cn1c(SCc2ccc(F)cc2)nnc1C3COc4ccccc4O3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E02 compound treatment 0.236 0.0105 0.15 0.257 0.0292 0.49 0.4527 0.8828 3064422 Maybridge4_002554 CCOC(=O)c1cncc(C#CCOC(=O)Nc2ccc(OC(F)(F)F)cc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E03 compound treatment 0.243 0.0175 0.25 0.264 0.0362 0.61 0.6065 0.9228 1569623 Maybridge4_002555 Clc1ccc(NC(=O)NCC2COc3ccccc3O2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E04 compound treatment 0.269 0.0435 0.62 0.22 -0.00778 -0.13 0.3473 0.5467 3064423 Maybridge4_002556 C/S(=N\S(=O)(=O)c1cccc2nsnc12)/c3ncc(Cl)cc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E05 compound treatment 0.277 0.0515 0.74 0.22 -0.00778 -0.13 0.4282 0.5727 1912560 Maybridge4_002557 CNC(=O)N(c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E06 compound treatment 0.263 0.0375 0.54 0.299 0.0712 1.2 1.2242 0.9345 1719037 Maybridge4_002558 Clc1ccc(cc1)C(=O)OCc2sccc2Oc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E07 compound treatment 0.298 0.0725 1.04 0.284 0.0562 0.94 1.4002 0.9989 3064424 Maybridge4_002559 Clc1ccc(SC(=O)c2csc(n2)c3ccc4nonc4c3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E08 compound treatment 0.278 0.0525 0.75 0.275 0.0472 0.79 1.0911 0.9996 1379034 Maybridge4_002560 Cc1ccc(SC(=O)c2ccc(C#Cc3ccccc3)o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E09 compound treatment 0.252 0.0265 0.38 0.255 0.0272 0.46 0.5907 0.9956 3178950 Maybridge4_002561 O=C1CC2Sc3ccccc3N=C2N1Cc4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E10 compound treatment 0.259 0.0335 0.48 0.294 0.0662 1.11 1.1244 0.9292 3064426 Maybridge4_002562 CCOC(=O)c1c(Oc2ccc(OC)cc2)c3cccc(c3nc1SC)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E11 compound treatment 0.297 0.0715 1.02 0.287 0.0592 0.99 1.4257 0.9999 3178951 Maybridge4_002563 Cn1cc(/C(=N/O)/N)c(=O)n(Cc2ccccc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E12 compound treatment 0.296 0.0705 1.01 0.221 -0.00678 -0.11 0.6323 0.6233 3178952 Maybridge4_002564 COC(=O)C(Cc1csc2ccc(Cl)cc12)NC(=O)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E13 compound treatment 0.251 0.0255 0.36 0.275 0.0472 0.79 0.818 0.9378 1645379 Maybridge4_002565 CC(C)n1cc(c2nc(C)cs2)c(=O)n(Cc3ccccc3)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E14 compound treatment 0.29 0.0645 0.92 0.289 0.0612 1.03 1.3786 0.9985 3064427 Maybridge4_002566 O=C(OCC#Cc1ccc(C#N)cc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E15 compound treatment 0.311 0.0855 1.22 0.306 0.0782 1.31 1.7928 0.9994 3178953 Maybridge4_002567 COC(=O)c1scc2c(Oc3ccccc3C(F)(F)F)cc(nc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E16 compound treatment 0.241 0.0155 0.22 0.217 -0.0108 -0.18 0.0285 0.0997 3178954 Maybridge4_002568 CC(C)(C)c1cc2nc(cc(N3CCN(CC3)c4ccc(cn4)C(F)(F)F)n2n1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E17 compound treatment 0.071 -0.155 -2.21 0.073 -0.155 -2.6 -3.3999 -0.9968 3064428 Maybridge4_002569 Cc1ccc(SCc2nccn2Cc3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E18 compound treatment 0.219 -0.00653 -0.09 0.283 0.0552 0.93 0.5893 0.6326 3178955 Maybridge4_002570 Cn1c(Cc2nc(no2)c3cnccn3)nnc1SCc4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E19 compound treatment 0.287 0.0615 0.88 0.256 0.0282 0.47 0.9566 0.9579 1530658 Maybridge4_002571 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)N=S(=O)(C)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E20 compound treatment 0.215 -0.0105 -0.15 0.208 -0.0198 -0.33 -0.3413 -0.9361 1174825 Maybridge4_002572 Cn1c(S)nnc1CCN(Cc2ccco2)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E21 compound treatment 0.223 -0.00253 -0.04 0.237 0.00922 0.15 0.0838 0.5274 1683285 Maybridge4_002573 COc1ccc(cc1)C(=O)CSC2=NCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E22 compound treatment 0.263 0.0375 0.54 0.253 0.0252 0.42 0.6783 0.9932 1586313 Maybridge4_002574 COc1ccc(NC(=O)Nc2cc(F)cc(F)c2)cc1OC3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E23 mock treatment 0.237 0.0115 0.16 0.247 0.0192 0.32 0.3441 0.9508 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 E24 mock treatment 0.196 -0.0295 -0.42 0.217 -0.0108 -0.18 -0.4266 -0.9284 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F01 compound treatment 0.212 -0.0135 -0.19 0.242 0.0142 0.24 0.0319 0.1038 1006297 Maybridge4_002575 Clc1ccc(CCc2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F02 compound treatment 0.273 0.0475 0.68 0.204 -0.0238 -0.4 0.1979 0.2512 3178956 Maybridge4_002576 Clc1ccccc1C(=O)NC(=O)Nc2ccc3C=CS(=O)(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F03 compound treatment 0.249 0.0235 0.34 0.248 0.0202 0.34 0.4773 1.0 1320469 Maybridge4_002577 O=C(Cc1ccc(CC(=O)c2ccccc2)cc1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F04 compound treatment 0.264 0.0385 0.55 0.26 0.0322 0.54 0.7715 1.0 1267104 Maybridge4_002578 Cc1c(CC(=O)Nc2ccc(Cl)cc2)sc3ccc(Cl)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F05 compound treatment 0.297 0.0715 1.02 0.258 0.0302 0.51 1.0815 0.9477 3064429 Maybridge4_002579 CCCn1c(=O)ccn(c2ccccc2C)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F06 compound treatment 0.268 0.0425 0.61 0.286 0.0582 0.98 1.1205 0.9738 1449737 Maybridge4_002580 O=C(CSC1=NCCc2ccccc12)c3ccc(cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F07 compound treatment 0.27 0.0445 0.64 0.242 0.0142 0.24 0.6185 0.9104 3064430 Maybridge4_002581 O=C(CNC(=O)OCc1ccccc1)ON2C(=O)CCC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F08 compound treatment 0.236 0.0105 0.15 0.219 -0.00878 -0.15 0.0017 0.0079 1291828 Maybridge4_002582 Cc1c(sc2ccc(Cl)cc12)c3cc(NC(=O)c4ccccc4)[nH]n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F09 compound treatment 0.288 0.0625 0.89 0.267 0.0392 0.66 1.0973 0.9887 3064431 Maybridge4_002583 CC(=O)OC1CCN(CC1)c2cc(nc3cc(Cl)cc(Cl)c23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F10 compound treatment 0.296 0.0705 1.01 0.318 0.0902 1.51 1.7835 0.9804 3178957 Maybridge4_002584 CNC(=S)c1sc2ccccc2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F11 compound treatment 0.334 0.108 1.55 0.298 0.0702 1.18 1.9304 0.9908 1269577 Maybridge4_002585 O=C(NCc1ccc(s1)S(=O)(=O)NCc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F12 compound treatment 0.309 0.0835 1.19 0.31 0.0822 1.38 1.82 0.9974 3064432 Maybridge4_002586 FC(F)(F)COc1ccc(c(OCC(F)(F)F)c1C#N)S(=O)(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F13 compound treatment 0.338 0.112 1.61 0.304 0.0762 1.28 2.0421 0.9936 1508849 Maybridge4_002587 CCC(C)c1ccccc1NC(=O)c2cc3cc(CC)ccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F14 compound treatment 0.294 0.0685 0.98 0.296 0.0682 1.14 1.5021 0.997 3064434 Maybridge4_002588 FC(F)(F)COc1ccc(SCC=C)c(OCC(F)(F)F)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F15 compound treatment 0.313 0.0875 1.25 0.298 0.0702 1.18 1.718 0.9996 1212532 Maybridge4_002589 Cc1cccc(NC(=O)NC(=O)c2ccc(s2)C(C)(C)C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F16 compound treatment 0.24 0.0145 0.21 0.25 0.0222 0.37 0.41 0.9614 3064435 Maybridge4_002590 C(N1CCC(=N1)/C=C/c2ccco2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F17 compound treatment 0.344 0.118 1.69 0.298 0.0702 1.18 2.0316 0.9843 1289651 Maybridge4_002591 CC(C)N(C(C)C)C(=O)NC(=O)c1ccc(F)cc1F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F18 compound treatment 0.258 0.0325 0.46 0.315 0.0872 1.46 1.3635 0.8878 3064458 Maybridge4_002592 NN/C(=N\S(=O)(=O)c1ccccc1)/Nc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F19 compound treatment 0.241 0.0155 0.22 0.233 0.00522 0.09 0.2184 0.9177 3064459 Maybridge4_002593 FC(F)(F)c1cccc(c1)n2c(n[nH]c2=S)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F20 compound treatment 0.047 -0.179 -2.55 0.047 -0.181 -3.03 -3.9512 -0.9963 3064460 Maybridge4_002594 NNC(=S)c1cc(Cl)cc(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F21 compound treatment 0.247 0.0215 0.31 0.241 0.0132 0.22 0.374 0.9873 3064461 Maybridge4_002595 NC(=O)c1ccc(CC(=O)c2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F22 compound treatment 0.22 -0.00553 -0.08 0.243 0.0152 0.26 0.1247 0.4662 3064462 Maybridge4_002596 C1CN=C(S1)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F23 mock treatment 0.226 4.69E-4 0.01 0.229 0.00122 0.02 0.0192 0.8922 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 F24 mock treatment 0.22 -0.00553 -0.08 0.226 -0.00178 -0.03 -0.0771 -0.9114 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G01 compound treatment 0.215 -0.0105 -0.15 0.279 0.0512 0.86 0.5014 0.5744 3064463 Maybridge4_002597 Cn1c(SCC(=O)c2ccccc2)nnc1C3COc4ccccc4O3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G02 compound treatment 0.266 0.0405 0.58 0.24 0.0122 0.21 0.5543 0.9026 3064464 Maybridge4_002598 COc1cc(nc2ccc(C)c(NC(=O)c3ccc(Cl)cc3)c12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G03 compound treatment 0.262 0.0365 0.52 0.265 0.0372 0.62 0.8106 0.996 1291018 Maybridge4_002599 Cc1ccc(NC(=S)NCC2COc3ccccc3O2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G04 compound treatment 0.225 -5.31E-4 -0.01 0.26 0.0322 0.54 0.377 0.6971 3064465 Maybridge4_002600 Cc1c(noc1C(=O)CN=S(=O)(C)c2ccc(cn2)C(F)(F)F)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G05 compound treatment 0.263 0.0375 0.54 0.236 0.00822 0.14 0.4765 0.861 3178958 Maybridge4_002601 COc1cccn(Cc2nnc(S)n2C)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G06 compound treatment 0.286 0.0605 0.86 0.27 0.0422 0.71 1.1127 0.9951 1395477 Maybridge4_002602 Clc1ccccc1C(=O)N2CCC(CC2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G07 compound treatment 0.307 0.0815 1.17 0.273 0.0452 0.76 1.3607 0.9784 3064466 Maybridge4_002603 Clc1ccc(cc1)C(=O)CSc2nc3CSCc3c(=O)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G08 compound treatment 0.308 0.0825 1.18 0.268 0.0402 0.68 1.3114 0.9649 1133834 Maybridge4_002604 O=c1[nH]c(=O)n(nc1C#N)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G09 compound treatment 0.292 0.0665 0.95 0.319 0.0912 1.53 1.7549 0.9737 3064468 Maybridge4_002605 CCOC(=O)c1nnc2c(Br)c(C)nn2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G10 compound treatment 0.328 0.102 1.47 0.237 0.00922 0.15 1.1458 0.7774 3178959 Maybridge4_002606 CSc1nn(cc1C(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G11 compound treatment 0.281 0.0555 0.79 0.266 0.0382 0.64 1.0146 0.9944 1533729 Maybridge4_002607 CC(C)n1cc(c2noc(n2)c3ccccc3Cl)c(=O)n(Cc4ccccc4)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G12 compound treatment 0.31 0.0845 1.21 0.286 0.0582 0.98 1.5453 0.9945 1333749 Maybridge4_002608 CSc1nc2c(Cl)cccc2c3n(C)n(Cc4ccc(Cl)cc4)c(=O)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G13 compound treatment 0.298 0.0725 1.04 0.316 0.0882 1.48 1.78 0.9848 1217547 Maybridge4_002609 CC(C)n1cc(c2nc(cs2)C(C)(C)C)c(=O)n(Cc3ccccc3)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G14 compound treatment 0.317 0.0915 1.31 0.298 0.0702 1.18 1.7585 0.9986 1707847 Maybridge4_002610 CCCn1c(=O)cc(N)n(c2ccc(Cl)cc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G15 compound treatment 0.289 0.0635 0.91 0.308 0.0802 1.35 1.594 0.9816 1123385 Maybridge4_002611 CCOC(=O)c1cn(Cc2cccc(Cl)c2)c3cc(C)nn3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G16 compound treatment 0.266 0.0405 0.58 0.299 0.0712 1.2 1.2545 0.9446 3064470 Maybridge4_002612 CCCn1c(=O)cc(N)n(c2ccc(OC(F)(F)F)cc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G17 compound treatment 0.282 0.0565 0.81 0.241 0.0132 0.22 0.728 0.8691 3178960 Maybridge4_002613 CC(C)(C)c1cc2nc(cc(Sc3ccccc3)n2n1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G18 compound treatment 0.307 0.0815 1.17 0.267 0.0392 0.66 1.2894 0.9634 3064471 Maybridge4_002614 Cn1c(Cc2nc(no2)c3cnccn3)nnc1SCC(=O)Nc4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G19 compound treatment 0.295 0.0695 0.99 0.251 0.0232 0.39 0.9782 0.9165 1167659 Maybridge4_002615 Cn1c(=O)c(cn(c2ccccc2)c1=O)c3noc(n3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G20 compound treatment 0.265 0.0395 0.56 0.269 0.0412 0.69 0.8884 0.9949 1420377 Maybridge4_002616 Clc1ccc(NC(=O)CCN(Cc2ccco2)S(=O)(=O)c3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G21 compound treatment 0.255 0.0295 0.42 0.242 0.0142 0.24 0.4668 0.9637 3064472 Maybridge4_002617 FC(F)(F)Oc1ccc(NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G22 compound treatment 0.256 0.0305 0.44 0.223 -0.00478 -0.08 0.2514 0.5674 1413855 Maybridge4_002618 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccc5nonc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G23 mock treatment 0.229 0.00347 0.05 0.232 0.00422 0.07 0.0852 0.9849 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 G24 mock treatment 0.219 -0.00653 -0.09 0.214 -0.0138 -0.23 -0.2296 -0.9205 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H01 compound treatment 0.22 -0.00553 -0.08 0.222 -0.00578 -0.1 -0.1246 -0.9949 3064474 Maybridge4_002619 Cc1ccccc1NC(=O)NC(=O)CC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H02 compound treatment 0.202 -0.0235 -0.34 0.223 -0.00478 -0.08 -0.2947 -0.8518 1680806 Maybridge4_002620 OC(=O)Cc1csc2ccc(Cl)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H03 compound treatment 0.243 0.0175 0.25 0.233 0.00522 0.09 0.2386 0.9012 3064475 Maybridge4_002621 COc1ccccc1CCn2cc(C#N)c(=O)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H04 compound treatment 0.205 -0.0205 -0.29 0.234 0.00622 0.1 -0.1339 -0.4295 3179054 Maybridge4_002622 Cc1cccc(NC(=S)N2CCOC2c3ccsc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H05 compound treatment 0.305 0.0795 1.14 0.293 0.0652 1.09 1.5778 0.9998 1623471 Maybridge4_002623 CCCn1c(=O)c(C#N)cn(C2CC2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H06 compound treatment 0.285 0.0595 0.85 0.281 0.0532 0.89 1.2331 0.9997 3179055 Maybridge4_002624 Cc1c(sc2ccc(Cl)cc12)c3ccnn3S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H07 compound treatment 0.271 0.0455 0.65 0.274 0.0462 0.78 1.0084 0.9962 3179056 Maybridge4_002625 COc1ccc(Cn2c(=O)n(c3cc(ccc3C)S(=O)C)c4nc[nH]c4c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H08 compound treatment 0.314 0.0885 1.27 0.312 0.0842 1.41 1.8943 0.9985 3064477 Maybridge4_002626 CC(C)c1ccc(/N=C/c2sc3ccccc3c2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H09 compound treatment 0.309 0.0835 1.19 0.271 0.0432 0.73 1.3571 0.9715 3179057 Maybridge4_002627 CCOC(=O)c1ccc2nc(cc(N3CCN(CC3)c4ccccc4)c2c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H10 compound treatment 0.281 0.0555 0.79 0.29 0.0622 1.04 1.2994 0.9908 3064478 Maybridge4_002628 Cc1c(/C=N/O)sc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H11 compound treatment 0.32 0.0945 1.35 0.26 0.0322 0.54 1.3379 0.9192 3064510 Maybridge4_002629 COc1ccc(cc1)c2ccnc(SCc3ccc(Cl)cc3Cl)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H12 compound treatment 0.273 0.0475 0.68 0.336 0.108 1.82 1.7645 0.9099 1135828 Maybridge4_002630 OC(=O)CC(NC(=O)Nc1ccccc1)c2ccsc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H13 compound treatment 0.32 0.0945 1.35 0.303 0.0752 1.26 1.8482 0.9994 1625372 Maybridge4_002631 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)C4CCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H14 compound treatment 0.309 0.0835 1.19 0.321 0.0932 1.56 1.9506 0.9911 3064512 Maybridge4_002632 COc1ccc(NS(=O)(=O)c2ccc(OCC(F)(F)F)c(C#N)c2OCC(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H15 compound treatment 0.322 0.0965 1.38 0.299 0.0712 1.2 1.8209 0.9974 3064513 Maybridge4_002633 CCOC(=O)c1sc(Nc2ccccc2C(F)(F)F)c(C(=O)OCC)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H16 compound treatment 0.286 0.0605 0.86 0.345 0.117 1.97 2.0028 0.9319 3064514 Maybridge4_002634 Clc1cccc(N/C(=N\S(=O)(=O)c2ccccc2)/NCCc3ccccn3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H17 compound treatment 0.337 0.111 1.59 0.349 0.121 2.03 2.5661 0.9927 3064515 Maybridge4_002635 CCOC(=O)NC(=S)Nc1cccc(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H18 compound treatment 0.315 0.0895 1.28 0.27 0.0422 0.71 1.406 0.9611 3179058 Maybridge4_002636 CCOC(=O)NC(=S)N1CCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H19 compound treatment 0.29 0.0645 0.92 0.31 0.0822 1.38 1.6278 0.9808 3179059 Maybridge4_002637 COc1ccc(CSC2=NCN(CN2)C3CC(C)CC(C)(C)C3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H20 compound treatment 0.283 0.0575 0.82 0.291 0.0632 1.06 1.3315 0.992 1226235 Maybridge4_002638 S=C(NCc1ccccc1)NCc2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H21 compound treatment 0.279 0.0535 0.76 0.292 0.0642 1.08 1.3029 0.9859 3179060 Maybridge4_002639 O=C(Cc1ccc(Oc2ccccc2)cc1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H22 compound treatment 0.235 0.00947 0.14 0.223 -0.00478 -0.08 0.039 0.2479 3064516 Maybridge4_002640 CCOC(=S)Nc1cccc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H23 mock treatment 0.231 0.00547 0.08 0.237 0.00922 0.15 0.1647 0.9501 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 H24 mock treatment 0.214 -0.0115 -0.16 0.207 -0.0208 -0.35 -0.3633 -0.9415 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I01 compound treatment 0.224 -0.00153 -0.02 0.236 0.00822 0.14 0.0821 0.5875 1349293 Maybridge4_002641 COC(=O)c1ccc-2c(c1)N(C)S(=O)(=O)c3cnc(SC)nc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I02 compound treatment 0.249 0.0235 0.34 0.205 -0.0228 -0.38 -0.033 -0.0649 3064517 Maybridge4_002642 NNC(=O)c1cncc(C#Cc2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I03 compound treatment 0.27 0.0445 0.64 0.203 -0.0248 -0.42 0.1557 0.2048 1297264 Maybridge4_002643 Clc1ccc(cc1)C(=O)NC(=S)NCC2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I04 compound treatment 0.293 0.0675 0.97 0.287 0.0592 0.99 1.3852 0.9999 1443440 Maybridge4_002644 COC(=O)c1csc(c1OC)S(=O)(=O)N=S(=O)(C)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I05 compound treatment 0.286 0.0605 0.86 0.279 0.0512 0.86 1.2195 1.0 3179061 Maybridge4_002645 COc1ccc2nc([nH]c2c1)S(=O)Cc3ncc(C)c(OC)c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I06 compound treatment 0.284 0.0585 0.84 0.292 0.0642 1.08 1.3535 0.9921 1207614 Maybridge4_002646 Clc1ccc(cc1)S(=O)(=O)N2CCC(CC2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I07 compound treatment 0.268 0.0425 0.61 0.266 0.0382 0.64 0.8831 0.9996 1176328 Maybridge4_002647 Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCC(=O)c4ccc(Cl)cc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I08 compound treatment 0.264 0.0385 0.55 0.194 -0.0338 -0.57 -0.0118 -0.015 1698489 Maybridge4_002648 Clc1ccc(Cn2c(=O)c(C#N)nn(c3ccccc3)c2=O)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I09 compound treatment 0.305 0.0795 1.14 0.33 0.102 1.72 2.0169 0.98 1223405 Maybridge4_002649 CCOC(=O)NC(=O)c1cn(CCc2ccncc2)c(=O)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I10 compound treatment 0.318 0.0925 1.32 0.304 0.0762 1.28 1.8398 0.9999 1257420 Maybridge4_002650 CSc1nn(cc1C(=O)N2CCCCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I11 compound treatment 0.314 0.0885 1.27 0.281 0.0532 0.89 1.5264 0.9855 3064519 Maybridge4_002651 CC(C)n1cc(/C(=N/O)/N)c(=O)n(Cc2ccccc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I12 compound treatment 0.329 0.103 1.48 0.309 0.0812 1.36 2.0104 0.9992 1544891 Maybridge4_002652 OC(=O)C1CNC(=O)N1C(=O)OCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I13 compound treatment 0.308 0.0825 1.18 0.303 0.0752 1.26 1.7268 0.9994 1689579 Maybridge4_002653 CCOC(=O)c1csc(n1)c2cn(C(C)C)c(=O)n(Cc3ccccc3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I14 compound treatment 0.314 0.0885 1.27 0.308 0.0802 1.35 1.8468 0.9995 3064520 Maybridge4_002654 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I15 compound treatment 0.312 0.0865 1.24 0.296 0.0682 1.14 1.6842 0.9993 3179062 Maybridge4_002655 Cc1[nH]c2ccccc2c1SCc3nnc(SCc4ccc(Cl)cc4)n3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I16 compound treatment 0.266 0.0405 0.58 0.298 0.0702 1.18 1.2427 0.9464 3064521 Maybridge4_002656 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I17 compound treatment 0.285 0.0595 0.85 0.276 0.0482 0.81 1.1737 0.9997 3179063 Maybridge4_002657 COc1ccc(Oc2cc(nc3cc(nn23)C(C)(C)C)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I18 compound treatment 0.286 0.0605 0.86 0.262 0.0342 0.57 1.0177 0.9802 3179064 Maybridge4_002658 CSc1cccc(NC(=O)N(Cc2ccccc2)C(=O)CC#N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I19 compound treatment 0.256 0.0305 0.44 0.265 0.0372 0.62 0.7499 0.9845 1399847 Maybridge4_002659 O=S1(=O)CC(N2CCCC2)c3ccccc31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I20 compound treatment 0.286 0.0605 0.86 0.26 0.0322 0.54 0.994 0.9744 3179065 Maybridge4_002660 FC(F)(F)c1cc(N2CCC(CC2)n3cccc3)c4ccccc4n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I21 compound treatment 0.269 0.0435 0.62 0.237 0.00922 0.15 0.5491 0.8569 3064522 Maybridge4_002661 O=C(OCc1ccc(C#Cc2ccccc2)s1)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I22 compound treatment 0.226 4.69E-4 0.01 0.176 -0.0518 -0.87 -0.6098 -0.7016 1065782 Maybridge4_002662 O=C(NCc1ccccc1)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I23 mock treatment 0.21 -0.0155 -0.22 0.198 -0.0298 -0.5 -0.5105 -0.9333 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 I24 mock treatment 0.229 0.00347 0.05 0.233 0.00522 0.09 0.097 0.9638 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J01 compound treatment 0.225 -5.31E-4 -0.01 0.238 0.0102 0.17 0.1159 0.6751 3064524 Maybridge4_002663 Cn1c(SCc2cc(F)cc(F)c2)nnc1c3ccc4nonc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J02 compound treatment 0.291 0.0655 0.94 0.24 0.0122 0.21 0.8072 0.842 3179066 Maybridge4_002664 Clc1ccc2scc(CC(=O)OCc3ccccc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J03 compound treatment 0.252 0.0265 0.38 0.231 0.00322 0.05 0.3059 0.7999 3064525 Maybridge4_002665 FC(F)(F)c1cc(N2CCCCC2)c3cccc(Cl)c3n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J04 compound treatment 0.053 -0.173 -2.47 0.059 -0.169 -2.83 -3.7481 -0.9976 3179067 Maybridge4_002666 NC(=S)Cc1c(Cl)sc2ccc(Cl)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J05 compound treatment 0.283 0.0575 0.82 0.257 0.0292 0.49 0.928 0.9695 1230774 Maybridge4_002667 O=c1c(C#N)cn(C2CC2)c(=O)n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J06 compound treatment 0.27 0.0445 0.64 0.251 0.0232 0.39 0.7253 0.9723 3064526 Maybridge4_002668 Cc1c(sc2ccc(Cl)cc12)c3ccnc(SCC=C)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J07 compound treatment 0.297 0.0715 1.02 0.277 0.0492 0.83 1.307 0.9944 1249532 Maybridge4_002669 Cc1cc(NC(=O)c2ccc3nonc3c2)on1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J08 compound treatment 0.338 0.112 1.61 0.242 0.0142 0.24 1.3063 0.8032 1640712 Maybridge4_002670 CN1C(=O)CC(Sc2ccccc12)c3ccsc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J09 compound treatment 0.339 0.113 1.62 0.305 0.0772 1.3 2.0641 0.9938 3064554 Maybridge4_002671 Cc1ccc2c(cc(nc2c1)C(F)(F)F)N3CC4CCC(CC4)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J10 compound treatment 0.101 -0.125 -1.78 0.076 -0.152 -2.55 -3.0609 -0.9847 3064555 Maybridge4_002672 Fc1ccc(NC2=NNC(=O)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J11 compound treatment 0.316 0.0905 1.29 0.276 0.0482 0.81 1.4873 0.9745 3064556 Maybridge4_002673 COc1ccc(cc1)c2ccnc(SCC(=O)N3CCOCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J12 compound treatment 0.309 0.0835 1.19 0.312 0.0842 1.41 1.8437 0.9965 1655959 Maybridge4_002674 CCCS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J13 compound treatment 0.291 0.0655 0.94 0.324 0.0962 1.61 1.8041 0.9664 1535225 Maybridge4_002675 CC(C)N(C(C)C)C(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J14 compound treatment 0.341 0.115 1.65 0.324 0.0962 1.61 2.3098 0.9999 3064558 Maybridge4_002676 FC(F)(F)COc1ccc(Br)c(OCC(F)(F)F)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J15 compound treatment 0.316 0.0905 1.29 0.294 0.0662 1.11 1.7009 0.9971 3064559 Maybridge4_002677 COC(=O)c1ccccc1SC(=O)c2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J16 compound treatment 0.046 -0.18 -2.57 0.044 -0.184 -3.08 -3.997 -0.9958 1497304 Maybridge4_002678 Clc1ccc(NC(=S)NS(=O)(=O)c2ccccc2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J17 compound treatment 0.309 0.0835 1.19 0.317 0.0892 1.5 1.9031 0.9937 1102994 Maybridge4_002679 CCOC(=O)NC(=S)c1cccn1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J18 compound treatment 0.323 0.0975 1.39 0.246 0.0182 0.31 1.202 0.8422 1203607 Maybridge4_002680 COc1ccc(OC)c(c1)S(=O)(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J19 compound treatment 0.313 0.0875 1.25 0.229 0.00122 0.02 0.8991 0.7186 3064560 Maybridge4_002681 S=C1NCN(Cc2ccncc2)CN1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J20 compound treatment 0.326 0.1 1.44 0.33 0.102 1.72 2.2293 0.9961 3179068 Maybridge4_002682 Cc1cc(Br)c(NC(=S)NC(=O)C(C)(C)C)c(Br)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J21 compound treatment 0.261 0.0355 0.51 0.293 0.0652 1.09 1.1328 0.9389 3064561 Maybridge4_002683 COC(=O)c1ccc2[nH]cnc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J22 compound treatment 0.254 0.0285 0.41 0.251 0.0232 0.39 0.5635 0.9998 3179069 Maybridge4_002684 O=c1[nH]nc([nH]1)N2CCSCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J23 mock treatment 0.236 0.0105 0.15 0.273 0.0452 0.76 0.6425 0.8306 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 J24 mock treatment 0.236 0.0105 0.15 0.23 0.00222 0.04 0.1322 0.8569 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K01 compound treatment 0.247 0.0215 0.31 0.225 -0.00278 -0.05 0.1841 0.5928 3064562 Maybridge4_002685 COC(=O)c1ccc2OCCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K02 compound treatment 0.254 0.0285 0.41 0.252 0.0242 0.41 0.5754 1.0 3179151 Maybridge4_002686 CCOC(=O)c1cncc(C#CCOC(=O)c2c(C)onc2c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K03 compound treatment 0.228 0.00247 0.04 0.254 0.0262 0.44 0.3361 0.7614 1273322 Maybridge4_002687 CCOC(=O)Cc1nn(Cc2nc(cs2)c3ccccc3)c(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K04 compound treatment 0.295 0.0695 0.99 0.279 0.0512 0.86 1.3105 0.9974 3179152 Maybridge4_002688 CN(CCOC(=O)c1ccccc1)c2cc(nc3ccccc23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K05 compound treatment 0.285 0.0595 0.85 0.218 -0.00978 -0.16 0.4854 0.5603 3179153 Maybridge4_002689 COc1cccn(Cc2nnc(SCC(=O)c3ccccc3)o2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K06 compound treatment 0.222 -0.00353 -0.05 0.266 0.0382 0.64 0.4179 0.6494 1551980 Maybridge4_002690 Clc1cc(Cl)cc(NC(=O)N2CCC(CC2)n3cccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K07 compound treatment 0.312 0.0865 1.24 0.253 0.0252 0.42 1.1739 0.898 3179154 Maybridge4_002691 CN(C)c1cc(nc2cc(nn12)C(C)(C)C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K08 compound treatment 0.296 0.0705 1.01 0.232 0.00422 0.07 0.7628 0.7549 3064563 Maybridge4_002692 CCCn1c(=O)c(nn(c2ccccc2)c1=O)/C(=N/O)/N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K09 compound treatment 0.294 0.0685 0.98 0.317 0.0892 1.5 1.7514 0.9788 1707363 Maybridge4_002693 Cc1ncn2cc([nH]c(=O)c12)c3ccc(Cl)cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K10 compound treatment 0.211 -0.0145 -0.21 0.219 -0.00878 -0.15 -0.2512 -0.9858 3179155 Maybridge4_002694 COC(=O)c1c(C)[nH]c(C)c1/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K11 compound treatment 0.33 0.104 1.49 0.286 0.0582 0.98 1.7476 0.9788 1478501 Maybridge4_002695 CC(C)n1cc(c2noc(n2)c3cccs3)c(=O)n(Cc4ccccc4)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K12 compound treatment 0.308 0.0825 1.18 0.281 0.0532 0.89 1.4657 0.9906 3179156 Maybridge4_002696 O=S(=O)(c1ccccc1)n2ccc(n2)c3ccc(C#Cc4ccccc4)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K13 compound treatment 0.312 0.0865 1.24 0.28 0.0522 0.88 1.4943 0.9858 1572994 Maybridge4_002697 CC(C)n1cc(c2nc(cs2)C(=O)NN)c(=O)n(Cc3ccccc3)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K14 compound treatment 0.314 0.0885 1.27 0.314 0.0862 1.45 1.918 0.9978 1626520 Maybridge4_002698 O=C(CSc1nc2ccccc2o1)N3CCC(CC3)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K15 compound treatment 0.285 0.0595 0.85 0.266 0.0382 0.64 1.0551 0.9903 3179157 Maybridge4_002699 COc1cc(nc2ccc(C#CCOC(=O)c3ccccc3)cc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K16 compound treatment 0.25 0.0245 0.35 0.261 0.0332 0.56 0.6417 0.9748 3064565 Maybridge4_002700 CCOC(=O)N1CCC(CC1)N/C=C(\C#N)/S(=O)(=O)c2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K17 compound treatment 0.288 0.0625 0.89 0.264 0.0362 0.61 1.0617 0.9824 3179158 Maybridge4_002701 Cc1ccc(cc1)S(=O)(=O)CCN2CCC(CC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K18 compound treatment 0.225 -5.31E-4 -0.01 0.302 0.0742 1.25 0.8755 0.7028 3064567 Maybridge4_002702 CSc1scc(NC(=O)c2ccc(Cl)cc2)c1S(=O)(=O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K19 compound treatment 0.246 0.0205 0.29 0.226 -0.00178 -0.03 0.1859 0.6316 3179159 Maybridge4_002703 O=S(=O)(/C(=C/N1CCN(CC1)C(c2ccccc2)c3ccccc3)/C#N)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K20 compound treatment 0.256 0.0305 0.44 0.246 0.0182 0.31 0.5244 0.985 3064568 Maybridge4_002704 COC(=O)c1scc2c(cc(nc12)C(F)(F)F)N3CCC(CC3)n4cccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K21 compound treatment 0.212 -0.0135 -0.19 0.206 -0.0218 -0.37 -0.3954 -0.9558 3179160 Maybridge4_002705 CCOC(=O)C1CCN(CC1)/C=C(\C#N)/S(=O)(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K22 compound treatment 0.191 -0.0345 -0.49 0.237 0.00922 0.15 -0.2398 -0.4634 1717162 Maybridge4_002706 CCCS(=O)(=O)c1cnc(nc1N)C2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K23 mock treatment 0.193 -0.0325 -0.47 0.194 -0.0338 -0.57 -0.7299 -0.9952 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 K24 mock treatment 0.22 -0.00553 -0.08 0.255 0.0272 0.46 0.2671 0.5761 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L01 compound treatment 0.266 0.0405 0.58 0.214 -0.0138 -0.23 0.2458 0.3942 1068568 Maybridge4_002707 CCOC(=O)c1c(C)oc(=O)c(Br)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L02 compound treatment 0.29 0.0645 0.92 0.241 0.0132 0.22 0.8089 0.8529 3064569 Maybridge4_002708 Clc1sc2ccc(Cl)cc2c1CC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L03 compound treatment 0.189 -0.0365 -0.52 0.228 2.19E-4 0.0 -0.3669 -0.7021 1726018 Maybridge4_002709 Clc1ccc(cc1)S(=O)(=O)CCN2CCN(CC2)C(c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L04 compound treatment 0.304 0.0785 1.12 0.267 0.0392 0.66 1.2591 0.9677 3064570 Maybridge4_002710 CCOC(=O)c1csc(Cc2c(Cl)sc3ccc(Cl)cc23)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L05 compound treatment 0.256 0.0305 0.44 0.242 0.0142 0.24 0.4769 0.9598 3179161 Maybridge4_002711 Fc1ccc(NC(=O)NC(=O)CC#N)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L06 compound treatment 0.274 0.0485 0.69 0.257 0.0292 0.49 0.837 0.9856 1493566 Maybridge4_002712 O=C(SC1=NCCc2ccccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L07 compound treatment 0.241 0.0155 0.22 0.244 0.0162 0.27 0.3489 0.9947 3064593 Maybridge4_002713 OC1(CC(=NN1)c2nccs2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L08 compound treatment 0.254 0.0285 0.41 0.233 0.00522 0.09 0.3499 0.84 3064595 Maybridge4_002714 Cc1c(/C=C/C(=O)Oc2ccc(C#N)cc2)sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L09 compound treatment 0.253 0.0275 0.39 0.243 0.0152 0.26 0.4584 0.9783 3064596 Maybridge4_002715 CCOC(=O)C1CCN(CC1)c2cc(nc3ccc(C)cc23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L10 compound treatment 0.052 -0.174 -2.48 0.043 -0.185 -3.1 -3.9481 -0.9939 3064597 Maybridge4_002716 CC(C)c1ccc(NC2=NNC(=O)C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L11 compound treatment 0.286 0.0605 0.86 0.264 0.0362 0.61 1.0414 0.9851 3482130 Maybridge4_002717 CC(C)(C)OC(=O)Nc1ncnc2n(cnc12)C3OC(CO)C4OC(C)(C)OC34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L12 compound treatment 0.24 0.0145 0.21 0.27 0.0422 0.71 0.6474 0.877 3064598 Maybridge4_002718 Cc1n[nH]c(C)c1Sc2nccc(n2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L13 compound treatment 0.278 0.0525 0.75 0.33 0.102 1.72 1.7438 0.9312 1572567 Maybridge4_002719 O=C(NCc1ccc(s1)S(=O)(=O)NCCN2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L14 compound treatment 0.275 0.0495 0.71 0.271 0.0432 0.73 1.0133 0.9999 3064599 Maybridge4_002720 NC(=O)c1csc(n1)c2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L15 compound treatment 0.285 0.0595 0.85 0.255 0.0272 0.46 0.9245 0.9575 3064600 Maybridge4_002721 Clc1ccc(cc1)c2nnc(o2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L16 compound treatment 0.231 0.00547 0.08 0.244 0.0162 0.27 0.2478 0.8749 3179162 Maybridge4_002722 CN(C)c1ccc(cc1)C2OCCN2C(=S)Nc3ccccc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L17 compound treatment 0.159 -0.0665 -0.95 0.162 -0.0658 -1.1 -1.4536 -0.9973 3064601 Maybridge4_002723 Cc1ccc(cc1)C(=O)CSC2=NCCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L18 compound treatment 0.274 0.0485 0.69 0.299 0.0712 1.2 1.3355 0.9664 3179163 Maybridge4_002724 CC(C)CNC(=S)N1CCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L19 compound treatment 0.228 0.00247 0.04 0.249 0.0212 0.36 0.2768 0.7734 1286430 Maybridge4_002725 S=C1NCN(CN1)C(Cc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L20 compound treatment 0.253 0.0275 0.39 0.294 0.0662 1.11 1.0637 0.9024 3064602 Maybridge4_002726 CCOC(=O)NC(=S)Nc1ccc(cc1)N2CC(C)OC(C)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L21 compound treatment 0.277 0.0515 0.74 0.278 0.0502 0.84 1.1166 0.9977 3179164 Maybridge4_002727 NNC(=O)C1CCC(CC1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L22 compound treatment 0.281 0.0555 0.79 0.31 0.0822 1.38 1.5368 0.9655 1090059 Maybridge4_002728 CCOC(=O)NC(=S)c1ccc[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L23 mock treatment 0.265 0.0395 0.56 0.262 0.0342 0.57 0.8053 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 L24 mock treatment 0.221 -0.00453 -0.06 0.203 -0.0248 -0.42 -0.3399 -0.8075 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M01 compound treatment 0.261 0.0355 0.51 0.267 0.0392 0.66 0.8242 0.9917 3179165 Maybridge4_002729 O=S(=O)(Cc1ccc2nonc2c1)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M02 compound treatment 0.255 0.0295 0.42 0.243 0.0152 0.26 0.4787 0.9712 3179166 Maybridge4_002730 CCOC(=O)c1cncc(C#CCOC(=O)c2ccc(Cl)cn2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M03 compound treatment 0.231 0.00547 0.08 0.274 0.0462 0.78 0.6038 0.7745 3064603 Maybridge4_002731 CN1c2sc(C)c(C)c2-c3nc(SCC(=O)C(C)(C)C)ncc3S1(=O)=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M04 compound treatment 0.042 -0.184 -2.63 0.041 -0.187 -3.13 -4.073 -0.9961 3179167 Maybridge4_002732 Clc1cc(Cl)cc(NC(=O)Nc2cc(n[nH]2)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M05 compound treatment 0.269 0.0435 0.62 0.265 0.0372 0.62 0.8814 1.0 1536304 Maybridge4_002733 Clc1ccc(cc1)c2csc(COc3ccc4nonc4c3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M06 compound treatment 0.254 0.0285 0.41 0.232 0.00422 0.07 0.338 0.8178 3179168 Maybridge4_002734 O=S(=O)(/C(=C/N1CCC(CC1)n2cccc2)/C#N)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M07 compound treatment 0.24 0.0145 0.21 0.235 0.00722 0.12 0.232 0.9675 1203004 Maybridge4_002735 Cn1c(S)nnc1CC2Sc3ccccc3NC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M08 compound treatment 0.276 0.0505 0.72 0.29 0.0622 1.04 1.2489 0.9837 1245628 Maybridge4_002736 CCCn1c(=O)c(C#N)nn(c2ccc(OC)cc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M09 compound treatment 0.257 0.0315 0.45 0.278 0.0502 0.84 0.9143 0.9568 1544442 Maybridge4_002737 CCOC(=O)NC(=O)c1cn(Cc2ccco2)c(=O)n(Cc3ccccc3)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M10 compound treatment 0.044 -0.182 -2.6 0.057 -0.171 -2.87 -3.8629 -0.9988 3064605 Maybridge4_002738 FC(F)(F)Oc1ccc(NC(=O)OC2CN(C2)C(c3ccccc3)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M11 compound treatment 0.237 0.0115 0.16 0.226 -0.00178 -0.03 0.0949 0.5689 3179169 Maybridge4_002739 Cn1c(CSc2cc(nc3ccccc23)C(F)(F)F)nnc1SCC(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M12 compound treatment 0.252 0.0265 0.38 0.292 0.0642 1.08 1.0299 0.9015 3179170 Maybridge4_002740 Cc1ccc2nc(cc(N3CCN(CC3)/C=C(/C#N)\S(=O)(=O)c4ccccn4)c2c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M13 compound treatment 0.228 0.00247 0.04 0.261 0.0332 0.56 0.4192 0.7504 3064606 Maybridge4_002741 COC(=O)c1scc2c(Sc3ccc(Cl)cc3)cc(nc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M14 compound treatment 0.261 0.0355 0.51 0.232 0.00422 0.07 0.4088 0.7981 1624356 Maybridge4_002742 Cn1c(S)nnc1CSC2CN(C2)C(c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M15 compound treatment 0.271 0.0455 0.65 0.268 0.0402 0.68 0.9372 0.9998 1609003 Maybridge4_002743 Clc1ccc(Cn2ccnc2COC(=O)c3ccccc3Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M16 compound treatment 0.238 0.0125 0.18 0.259 0.0312 0.52 0.4966 0.8972 3179171 Maybridge4_002744 CCOC(=O)N1CCC(CC1)N/C=C(\C#N)/S(=O)(=O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M17 compound treatment 0.275 0.0495 0.71 0.281 0.0532 0.89 1.1319 0.9933 3064607 Maybridge4_002745 Clc1ccc(SC2CS(=O)(=O)c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M18 compound treatment 0.257 0.0315 0.45 0.266 0.0382 0.64 0.7719 0.985 3179261 Maybridge4_002746 COc1ccc(cc1OC)S(=O)(=O)N(CCC(=O)O)Cc2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M19 compound treatment 0.257 0.0315 0.45 0.262 0.0342 0.57 0.7244 0.9927 3064609 Maybridge4_002747 CC(C)(C)S(=O)(=O)/C(=C/N1CCN(CC1)C(c2ccccc2)c3ccccc3)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M20 compound treatment 0.222 -0.00353 -0.05 0.205 -0.0228 -0.38 -0.3061 -0.7936 1049769 Maybridge4_002748 CC(C)NC(=O)c1ccccc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M21 compound treatment 0.247 0.0215 0.31 0.206 -0.0218 -0.37 -0.0414 -0.0866 3063912 Maybridge4_002749 CCOC(=O)C1CCN(CC1)/C=C(\C#N)/S(=O)(=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M22 compound treatment 0.281 0.0555 0.79 0.246 0.0182 0.31 0.7772 0.9141 1471006 Maybridge4_002750 Nc1cc(=O)n(Cc2ccccc2)c(=O)n1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M23 mock treatment 0.237 0.0115 0.16 0.263 0.0352 0.59 0.534 0.8704 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 M24 mock treatment 0.227 0.00147 0.02 0.216 -0.0118 -0.2 -0.125 -0.6284 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N01 compound treatment 0.217 -0.00853 -0.12 0.25 0.0222 0.37 0.1774 0.4521 3063913 Maybridge4_002751 Cn1c(SCC(=O)NCC=C)nnc1c2ccc3nonc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N02 compound treatment 0.232 0.00647 0.09 0.228 2.19E-4 0.0 0.068 0.7346 3063914 Maybridge4_002752 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N03 compound treatment 0.248 0.0225 0.32 0.263 0.0352 0.59 0.6452 0.959 1156673 Maybridge4_002753 O=S(=O)(N1CCC(CC1)C(c2ccccc2)c3ccccc3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N04 compound treatment 0.153 -0.0725 -1.04 0.085 -0.143 -2.4 -2.4281 -0.9298 3063915 Maybridge4_002754 CNC(=O)c1csc(Cc2c(Cl)sc3ccc(Cl)cc23)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N05 compound treatment 0.263 0.0375 0.54 0.266 0.0382 0.64 0.8326 0.996 1656700 Maybridge4_002755 COc1ccc(cc1)n2c(N)cc(=O)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N06 compound treatment 0.267 0.0415 0.59 0.304 0.0762 1.28 1.324 0.9389 3063916 Maybridge4_002756 CN(c1ccccc1)S(=O)(=O)c2sc3ccc(Cl)cc3c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N07 compound treatment 0.227 0.00147 0.02 0.27 0.0422 0.71 0.5159 0.7278 3179262 Maybridge4_002757 CCOC(=O)N1CCN(CC1)c2cc(nc3c(Cl)cccc23)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N08 compound treatment 0.276 0.0505 0.72 0.279 0.0512 0.86 1.1183 0.9962 3179263 Maybridge4_002758 COc1ccc(OC(=O)/C=C/c2sc3ccccc3c2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N09 compound treatment 0.264 0.0385 0.55 0.231 0.00322 0.05 0.4273 0.7728 3063917 Maybridge4_002759 CCOC(=O)c1ccc2nc(cc(NC3CCN(Cc4ccccc4)CC3)c2c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N10 compound treatment 0.231 0.00547 0.08 0.245 0.0172 0.29 0.2597 0.8673 3179264 Maybridge4_002760 CNC(=S)NCc1sc2ccccc2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N11 compound treatment 0.231 0.00547 0.08 0.258 0.0302 0.51 0.414 0.8066 1569047 Maybridge4_002761 CCc1ccc2[nH]c(cc2c1)C(=O)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N12 compound treatment 0.251 0.0255 0.36 0.254 0.0262 0.44 0.5688 0.9956 3063918 Maybridge4_002762 Cc1nc2cc(nn2c(C)c1Sc3nccc(n3)c4cccnc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N13 compound treatment 0.214 -0.0115 -0.16 0.254 0.0262 0.44 0.1945 0.414 1306797 Maybridge4_002763 COc1cc2CCN=C(c3ccc(Cl)cc3)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N14 compound treatment 0.284 0.0585 0.84 0.29 0.0622 1.04 1.3298 0.9939 3063920 Maybridge4_002764 C(N1CCC(=N1)c2cccs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N15 compound treatment 0.234 0.00847 0.12 0.23 0.00222 0.04 0.112 0.8837 3179265 Maybridge4_002765 CC(C)(C)Sc1nc2ccccc2[nH]c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N16 compound treatment 0.261 0.0355 0.51 0.338 0.11 1.85 1.6668 0.8689 1707053 Maybridge4_002766 CCOC(=O)NC(=S)c1ccc(OC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N17 compound treatment 0.211 -0.0145 -0.21 0.305 0.0772 1.3 0.7695 0.5862 3179266 Maybridge4_002767 Clc1cccc(c1)C(=O)Nc2nccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N18 compound treatment 0.278 0.0525 0.75 0.265 0.0372 0.62 0.9724 0.9958 1022738 Maybridge4_002768 NS(=O)(=O)c1ccc(Cl)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N19 compound treatment 0.269 0.0435 0.62 0.233 0.00522 0.09 0.5016 0.7988 3179267 Maybridge4_002769 Cc1nnsc1c2nnc(S)n2C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N20 compound treatment 0.281 0.0555 0.79 0.305 0.0772 1.3 1.4775 0.9723 1602154 Maybridge4_002770 CC1CN(CC(C)O1)c2ccc(NC(=S)Nc3ccc(cc3)N4CC(C)OC(C)C4)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N21 compound treatment 0.279 0.0535 0.76 0.285 0.0572 0.96 1.2199 0.9936 1095185 Maybridge4_002771 Nc1c(sc2ncccc12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N22 compound treatment 0.256 0.0305 0.44 0.267 0.0392 0.66 0.7736 0.98 3063921 Maybridge4_002772 OCCNC(=S)NC1CCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N23 mock treatment 0.216 -0.00953 -0.14 0.245 0.0172 0.29 0.108 0.3378 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 N24 mock treatment 0.25 0.0245 0.35 0.229 0.00122 0.02 0.2619 0.7472 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O01 compound treatment 0.26 0.0345 0.49 0.25 0.0222 0.37 0.6123 0.9905 1227681 Maybridge4_002773 CSc1ncc(C(=O)NN)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O02 compound treatment 0.282 0.0565 0.81 0.232 0.00422 0.07 0.6212 0.7662 3179268 Maybridge4_002774 Cn1c(CN2C(=O)CSc3ccc(cc23)C(F)(F)F)nnc1SCc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O03 compound treatment 0.223 -0.00253 -0.04 0.253 0.0252 0.42 0.2737 0.6443 1733846 Maybridge4_002775 CNC(=O)c1cc(Br)cc2CCOc21 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O04 compound treatment 0.242 0.0165 0.24 0.272 0.0442 0.74 0.6914 0.8879 3179269 Maybridge4_002776 FC(F)(F)Oc1ccc(NC(=O)Nc2cc(n[nH]2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O05 compound treatment 0.249 0.0235 0.34 0.263 0.0352 0.59 0.6553 0.9641 3063922 Maybridge4_002777 CCOC(=O)c1sc(COc2ccc3nonc3c2)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O06 compound treatment 0.234 0.00847 0.12 0.245 0.0172 0.29 0.29 0.9255 3179270 Maybridge4_002778 CC(C)(C)S(=O)(=O)/C(=C/N1CCC(CC1)n2cccc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O07 compound treatment 0.239 0.0135 0.19 0.238 0.0102 0.17 0.2575 0.9983 3063923 Maybridge4_002779 CCSc1cc(nc2cc(nn12)C(C)(C)C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O08 compound treatment 0.235 0.00947 0.14 0.284 0.0562 0.94 0.763 0.8004 3063924 Maybridge4_002780 CSc1nn(cc1C(=O)Nc2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O09 compound treatment 0.233 0.00747 0.11 0.214 -0.0138 -0.23 -0.088 -0.3455 1030103 Maybridge4_002781 O=c1[nH]c(=O)n(cc1C#N)C2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O10 compound treatment 0.224 -0.00153 -0.02 0.246 0.0182 0.31 0.2007 0.6548 1309716 Maybridge4_002782 CSc1nc2c(Cl)cccc2c3n(C)[nH]c(=O)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O11 compound treatment 0.223 -0.00253 -0.04 0.239 0.0112 0.19 0.1075 0.5609 1606150 Maybridge4_002783 Cc1[nH]c2ccccc2c1SCC(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O12 compound treatment 0.247 0.0215 0.31 0.244 0.0162 0.27 0.4096 0.9982 1579140 Maybridge4_002784 CCOC(=O)Cn1n(C)c2c(cnc3n(C)nc(C)c32)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O13 compound treatment 0.231 0.00547 0.08 0.252 0.0242 0.41 0.3427 0.828 1697318 Maybridge4_002785 CCOC(=O)Cn1c(=O)c(cn(C(C)C)c1=O)C(=S)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O14 compound treatment 0.135 -0.0905 -1.29 0.135 -0.0928 -1.56 -2.0168 -0.9958 1214988 Maybridge4_002786 Clc1ccc(OC(=O)c2c(nnc3ccccc23)c4ccccc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O15 compound treatment 0.212 -0.0135 -0.19 0.238 0.0102 0.17 -0.0156 -0.0603 3063958 Maybridge4_002787 COc1cc(nc2ccc(C#CCOC(=O)Nc3ccccc3)cc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O16 compound treatment 0.235 0.00947 0.14 0.224 -0.00378 -0.06 0.0509 0.3403 3063959 Maybridge4_002788 Clc1ccc(SCc2n[nH]c(=O)c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O17 compound treatment 0.244 0.0185 0.26 0.263 0.0352 0.59 0.6048 0.9341 1427896 Maybridge4_002789 Cc1ccc(cc1)S(=O)(=O)C2CS(=O)(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O18 compound treatment 0.24 0.0145 0.21 0.22 -0.00778 -0.13 0.054 0.2206 3063960 Maybridge4_002790 COc1ccc(cc1OC)S(=O)(=O)N(CCC#N)C2CCCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O19 compound treatment 0.237 0.0115 0.16 0.223 -0.00478 -0.08 0.0593 0.3245 1698976 Maybridge4_002791 Cn1c(=O)c(cn(c2ccccc2)c1=O)c3nc(cs3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O20 compound treatment 0.217 -0.00853 -0.12 0.249 0.0212 0.36 0.1655 0.4397 3179271 Maybridge4_002792 CCOC(=O)C1CCC(N1C(=O)Nc2ccc(Cl)cc2)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O21 compound treatment 0.247 0.0215 0.31 0.269 0.0412 0.69 0.7063 0.9332 3063961 Maybridge4_002793 FC(F)(F)c1cccc(NC(=O)CN2C(=O)CSc3ccc(cc23)C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O22 compound treatment 0.221 -0.00453 -0.06 0.229 0.00122 0.02 -0.0314 -0.4615 1142886 Maybridge4_002794 Nc1nc(ncc1S(=O)(=O)c2ccccc2)C3COc4ccccc4O3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O23 mock treatment 0.219 -0.00653 -0.09 0.205 -0.0228 -0.38 -0.3364 -0.8547 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 O24 mock treatment 0.231 0.00547 0.08 0.205 -0.0228 -0.38 -0.2151 -0.551 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P01 compound treatment 0.217 -0.00853 -0.12 0.235 0.00722 0.12 -6.0E-4 -0.0036 1672516 Maybridge4_002795 O=C(Nc1ccc2nonc2c1)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P02 compound treatment 0.231 0.00547 0.08 0.267 0.0392 0.66 0.5208 0.7856 3179272 Maybridge4_002796 FC(F)(F)c1ccccc1NC(=S)Nc2ccc3C=CS(=O)(=O)c3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P03 compound treatment 0.243 0.0175 0.25 0.224 -0.00378 -0.06 0.1318 0.5113 3063964 Maybridge4_002797 CCCn1c(=O)n(c2ccccc2C)c3[nH]cnc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P04 compound treatment 0.242 0.0165 0.24 0.275 0.0472 0.79 0.727 0.8793 1153341 Maybridge4_002798 Cc1c(CC(=O)NN)sc2ccc(Cl)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P05 compound treatment 0.245 0.0195 0.28 0.237 0.00922 0.15 0.3063 0.9615 1289003 Maybridge4_002799 Cc1ccccc1n2ccc(=O)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P06 compound treatment 0.055 -0.171 -2.44 0.057 -0.171 -2.87 -3.7516 -0.9968 3179273 Maybridge4_002800 Cc1c(sc2ccc(Cl)cc12)C(=O)CC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P07 compound treatment 0.249 0.0235 0.34 0.227 -7.81E-4 -0.01 0.2281 0.679 3063965 Maybridge4_002801 CSc1nnc(CNC(=O)OC(C)(C)C)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P08 compound treatment 0.265 0.0395 0.56 0.252 0.0242 0.41 0.6866 0.987 3179274 Maybridge4_002802 Cc1c(COC(=O)c2ccccc2)sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P09 compound treatment 0.24 0.0145 0.21 0.249 0.0212 0.36 0.3982 0.9667 3179275 Maybridge4_002803 Cn1c(CNC(=O)c2cccs2)nnc1SCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P10 compound treatment 0.273 0.0475 0.68 0.29 0.0622 1.04 1.2185 0.9783 3063968 Maybridge4_002804 Cc1c(CNC(=O)c2ccc(cc2)C(F)(F)F)sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P11 compound treatment 0.252 0.0265 0.38 0.211 -0.0168 -0.28 0.0685 0.1453 1496234 Maybridge4_002805 CCc1ccc2[nH]c(cc2c1)C(=O)NC(C)COC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P12 compound treatment 0.121 -0.105 -1.5 0.123 -0.105 -1.76 -2.3008 -0.9967 1637130 Maybridge4_002806 Clc1ccc(cc1)N2N=C(CSc3nccc(n3)c4cccnc4)CC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P13 compound treatment 0.301 0.0755 1.08 0.29 0.0622 1.04 1.5017 0.9999 3179276 Maybridge4_002807 Clc1ccc(cc1)c2ccc(s2)C(=O)OCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P14 compound treatment 0.239 0.0135 0.19 0.255 0.0272 0.46 0.4593 0.9263 3063969 Maybridge4_002808 CN1CCC(=N1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P15 compound treatment 0.225 -5.31E-4 -0.01 0.239 0.0112 0.19 0.1278 0.678 3179277 Maybridge4_002809 FC(F)(F)c1ccc(CNC(=O)N/C=C/c2cccs2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P16 compound treatment 0.245 0.0195 0.28 0.218 -0.00978 -0.16 0.0808 0.25 3063970 Maybridge4_002810 Oc1nnc(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P17 compound treatment 0.268 0.0425 0.61 0.243 0.0152 0.26 0.6102 0.9259 3179278 Maybridge4_002811 COc1ccc(cc1)c2nc(cs2)c3ccc(C)cc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P18 compound treatment 0.241 0.0155 0.22 0.226 -0.00178 -0.03 0.1353 0.6061 1676105 Maybridge4_002812 COc1ccc(cc1)c2nc(nc(=O)[nH]2)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P19 compound treatment 0.226 4.69E-4 0.01 0.239 0.0112 0.19 0.1379 0.7318 3063971 Maybridge4_002813 OCc1cnc(S)n1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P20 compound treatment 0.243 0.0175 0.25 0.243 0.0152 0.26 0.3573 0.9999 1134458 Maybridge4_002814 CC1CN(CC(C)O1)c2ccc(NC(=S)NN)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P21 compound treatment 0.271 0.0455 0.65 0.267 0.0392 0.66 0.9253 1.0 3063972 Maybridge4_002815 Cc1ccc2sc(cc2c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P22 compound treatment 0.137 -0.0885 -1.27 0.159 -0.0688 -1.15 -1.7117 -0.9989 3063973 Maybridge4_002816 CCCc1ccc(NC(=S)OCC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P23 mock treatment 0.224 -0.00153 -0.02 0.224 -0.00378 -0.06 -0.0604 -0.8991 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2056 P24 mock treatment 0.214 -0.0115 -0.16 0.213 -0.0148 -0.25 -0.2921 -0.9803 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A01 compound treatment 0.228 0.00309 0.04 0.202 -0.0262 -0.44 -0.2799 -0.6328 3179279 Maybridge4_002817 CCOC(=S)Nc1ccc(I)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A02 compound treatment 0.271 0.0461 0.66 0.252 0.0238 0.4 0.7484 0.9711 3179280 Maybridge4_002818 Cn1c(/C=C/C=C/N2CCCC2)nc3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A03 compound treatment 0.234 0.00909 0.13 0.324 0.0958 1.61 1.2287 0.7618 3063974 Maybridge4_002819 CCCn1c(n[nH]c1=O)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A04 compound treatment 0.254 0.0291 0.42 0.232 0.00378 0.06 0.3391 0.8056 3179380 Maybridge4_002820 CCOC(=O)c1cnc(S/C=C/C(=O)c2ccc(Cl)cc2)nc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A05 compound treatment 0.239 0.0141 0.2 0.254 0.0258 0.43 0.4485 0.9396 1487054 Maybridge4_002821 Cc1ccccc1S(=O)c2ccccc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A06 compound treatment 0.253 0.0281 0.4 0.246 0.0178 0.3 0.4952 0.9893 3064003 Maybridge4_002822 N(/C=N/c1ccc2ccccc2c1)c3ccc4ccccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A07 compound treatment 0.255 0.0301 0.43 0.303 0.0748 1.26 1.1919 0.8983 1198685 Maybridge4_002823 CC(C)CC(NC(=O)Nc1cccc2ccccc12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A08 compound treatment 0.207 -0.0179 -0.26 0.241 0.0128 0.21 -0.0294 -0.0881 3064005 Maybridge4_002824 FC(F)(F)c1ncncc1c2nnnn2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A09 compound treatment 0.265 0.0401 0.57 0.23 0.00178 0.03 0.4267 0.743 3064006 Maybridge4_002825 CN(C)/C=C(\C(=S)c1ccccc1)/c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A10 compound treatment 0.094 -0.131 -1.87 0.095 -0.133 -2.24 -2.9051 -0.9961 3064007 Maybridge4_002826 Clc1ccc(O/C=C/C(=O)c2ccc(Br)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A11 compound treatment 0.217 -0.00791 -0.11 0.243 0.0148 0.25 0.0955 0.3501 1652788 Maybridge4_002827 CN1C(=O)C(Cc2ccccc2)(Cc3ccccc3)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A12 compound treatment 0.235 0.0101 0.14 0.196 -0.0322 -0.54 -0.2803 -0.5008 3064008 Maybridge4_002828 O=c1[nH]c2ccccc2c(=O)n1CCNCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A13 compound treatment 0.215 -0.00991 -0.14 0.265 0.0368 0.62 0.3363 0.531 3064009 Maybridge4_002829 C/C(=N\O)/C(=O)Nc1cccc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A14 compound treatment 0.045 -0.18 -2.57 0.05 -0.178 -2.99 -3.9347 -0.9972 3179381 Maybridge4_002830 Clc1ccc(/C=C(\C#N)/c2c[nH]c3ccccc23)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A15 compound treatment 0.244 0.0191 0.27 0.212 -0.0162 -0.27 6.0E-4 0.0016 3179382 Maybridge4_002831 O=C(/C=C\1/Nc2[nH]c(=S)[nH]c(=O)c2NC1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A16 compound treatment 0.259 0.0341 0.49 0.248 0.0198 0.33 0.5796 0.9824 3064010 Maybridge4_002832 FC(F)(F)c1ccc(/C=C(\C#N)/c2cn(C(=O)C3CCC3)c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A17 compound treatment 0.205 -0.0199 -0.28 0.237 0.00878 0.15 -0.0971 -0.3029 1477955 Maybridge4_002833 Cc1c(O)c(C(=O)c2nn[nH]n2)c(=O)n(c3ccccc3)c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A18 compound treatment 0.22 -0.00491 -0.07 0.231 0.00278 0.05 -0.0166 -0.1971 1152993 Maybridge4_002834 COc1ccc(CC(=O)NN2C(=O)CSCC2=O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A19 compound treatment 0.215 -0.00991 -0.14 0.237 0.00878 0.15 0.004 0.0197 3179383 Maybridge4_002835 O=C(C/C(=C\1/CCc2ccccc2C1=O)/c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A20 compound treatment 0.26 0.0351 0.5 0.248 0.0198 0.33 0.5897 0.9799 3179384 Maybridge4_002836 CC1CC(CC(C)(C)C1)NC(=S)NCc2csc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A21 compound treatment 0.186 -0.0389 -0.56 0.195 -0.0332 -0.56 -0.7877 -1.0 1438428 Maybridge4_002837 CC12CCC3C(CC=C4CC(O)CCC34CO)C2CCC1OC(=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A22 compound treatment 0.196 -0.0289 -0.41 0.199 -0.0292 -0.49 -0.6391 -0.9964 3179385 Maybridge4_002838 CC(=O)Nc1ccc(cc1)C2=N/C(=C/c3cn(C(=O)C)c4ccccc34)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A23 mock treatment 0.222 -0.00291 -0.04 0.208 -0.0202 -0.34 -0.2694 -0.7878 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 A24 mock treatment 0.217 -0.00791 -0.11 0.216 -0.0122 -0.21 -0.225 -0.9607 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B01 compound treatment 0.224 -9.06E-4 -0.01 0.243 0.0148 0.25 0.1663 0.6692 1595249 Maybridge4_002839 COc1ccc(cc1)C2C(C(=O)O)c3ccccc3C(=O)N2Cc4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B02 compound treatment 0.237 0.0121 0.17 0.273 0.0448 0.75 0.6538 0.8477 3064011 Maybridge4_002840 FC(F)(F)c1nnc(Nc2cccnc2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B03 compound treatment 0.256 0.0311 0.44 0.318 0.0898 1.51 1.38 0.8783 1011958 Maybridge4_002841 CC(=O)Nc1ccc(Cc2ccc(NC(=O)C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B04 compound treatment 0.23 0.00509 0.07 0.257 0.0288 0.48 0.3931 0.8047 3179386 Maybridge4_002842 O=C1N(C2CCCCC2)/C(=N/C3CCCCC3)/SC41CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B05 compound treatment 0.283 0.0581 0.83 0.224 -0.00422 -0.07 0.5375 0.6445 3064012 Maybridge4_002843 CS/C(=N\C#N)/N=c\1/nc(SC)n(C)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B06 compound treatment 0.195 -0.0299 -0.43 0.211 -0.0172 -0.29 -0.5068 -0.9818 3179387 Maybridge4_002844 Cc1cc(S)nc(n1)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B07 compound treatment 0.26 0.0351 0.5 0.299 0.0708 1.19 1.195 0.9266 3064013 Maybridge4_002845 Cc1csc(Nc2c(C)cccc2C)[n+]1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B08 compound treatment 0.267 0.0421 0.6 0.258 0.0298 0.5 0.7792 0.9957 3179388 Maybridge4_002846 Cc1nc(nc(NCCNc2cc(ccn2)C(F)(F)F)c1Cl)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B09 compound treatment 0.244 0.0191 0.27 0.293 0.0648 1.09 0.9619 0.8581 3064014 Maybridge4_002847 Clc1ccc(/C=C(\C#N)/c2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B10 compound treatment 0.239 0.0141 0.2 0.27 0.0418 0.7 0.6384 0.8749 1673007 Maybridge4_002848 COc1ccc(CCNC(=O)C(Sc2ccc(Cl)cc2)c3ccccc3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B11 compound treatment 0.272 0.0471 0.67 0.267 0.0388 0.65 0.9366 0.9999 1278976 Maybridge4_002849 CSc1nc2ccccc2c(=O)n1CCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B12 compound treatment 0.243 0.0181 0.26 0.269 0.0408 0.68 0.667 0.9115 3179389 Maybridge4_002850 CCOC(=O)/C(=N\O)/C1=CSC2=NNC(C)(C)N12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B13 compound treatment 0.221 -0.00391 -0.06 0.217 -0.0112 -0.19 -0.1727 -0.879 1697626 Maybridge4_002851 Oc1ccccc1C(=O)Nc2ccc(NC(=O)c3ccc(Cl)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B14 compound treatment 0.244 0.0191 0.27 0.225 -0.00322 -0.05 0.1549 0.5565 1029066 Maybridge4_002852 OC(Cc1cccnc1)(c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B15 compound treatment 0.262 0.0371 0.53 0.242 0.0138 0.23 0.5387 0.9308 3179390 Maybridge4_002853 Cn/1c(cs\c1=N/C(=S)NCCc2ccccc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B16 compound treatment 0.233 0.00809 0.12 0.232 0.00378 0.06 0.1267 0.96 1414388 Maybridge4_002854 Cc1ccc2onc(OC(=O)NC(C)(C)C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B17 compound treatment 0.258 0.0331 0.47 0.242 0.0138 0.23 0.4983 0.9458 3064015 Maybridge4_002855 CS/C(=N\c1ccc(Cl)cc1)/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B18 compound treatment 0.157 -0.0679 -0.97 0.136 -0.0922 -1.55 -1.7813 -0.9748 1450668 Maybridge4_002856 CNC(=O)Nc1cccc(c1)c2cc(no2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B19 compound treatment 0.216 -0.00891 -0.13 0.211 -0.0172 -0.29 -0.2944 -0.9322 1567287 Maybridge4_002857 COc1cc(CSc2nnnn2c3ccc(C)cc3C)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B20 compound treatment 0.233 0.00809 0.12 0.243 0.0148 0.25 0.2573 0.9398 1505699 Maybridge4_002858 COC(=O)c1c(NC(=O)N(C)C)onc1c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B21 compound treatment 0.245 0.0201 0.29 0.252 0.0238 0.4 0.4855 0.987 1506761 Maybridge4_002859 NCCSC(=S)NC1CCCCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B22 compound treatment 0.231 0.00609 0.09 0.267 0.0388 0.65 0.5219 0.7947 3064016 Maybridge4_002860 CN(C)/C=N/C1NC(=O)N(C)C(=N1)C2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B23 mock treatment 0.249 0.0241 0.34 0.247 0.0188 0.32 0.4666 0.999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 B24 mock treatment 0.205 -0.0199 -0.28 0.246 0.0178 0.3 0.0097 0.0235 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C01 compound treatment 0.232 0.00709 0.1 0.196 -0.0322 -0.54 -0.3106 -0.5646 1030385 Maybridge4_002861 S=C(NC1CCCCC1)C(=S)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C02 compound treatment 0.25 0.0251 0.36 0.237 0.00878 0.15 0.358 0.9227 3064017 Maybridge4_002862 Clc1ccc(cc1)C(=O)c2[n+]([N-]C#N)ccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C03 compound treatment 0.269 0.0441 0.63 0.309 0.0808 1.36 1.4047 0.9394 3179391 Maybridge4_002863 CCCn1c(n[nH]c1=O)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C04 compound treatment 0.121 -0.104 -1.49 0.115 -0.113 -1.9 -2.3946 -0.9926 3064018 Maybridge4_002864 O=C(/C=C/Sc1ccccn1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C05 compound treatment 0.257 0.0321 0.46 0.278 0.0498 0.84 0.9154 0.9602 3179392 Maybridge4_002865 CCNS(=O)(=O)c1ccc(Cl)cc1I 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C06 compound treatment 0.281 0.0561 0.8 0.31 0.0818 1.37 1.5379 0.9673 3064054 Maybridge4_002866 CC1C(O/C(=N\S(=O)(=O)c2ccc(Cl)cc2)/N1C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C07 compound treatment 0.222 -0.00291 -0.04 0.244 0.0158 0.26 0.1579 0.5889 1049317 Maybridge4_002867 OC(=O)CCNC(=O)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C08 compound treatment 0.262 0.0371 0.53 0.312 0.0838 1.41 1.3695 0.9112 3064055 Maybridge4_002868 Oc1c([I+]c2ccccc2)c(=O)[nH]c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C09 compound treatment 0.248 0.0231 0.33 0.297 0.0688 1.15 1.0499 0.8743 3064056 Maybridge4_002869 N#CC(Cc1ccccc1)(Cc2ccccc2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C10 compound treatment 0.197 -0.0279 -0.4 0.233 0.00478 0.08 -0.2255 -0.5539 1357025 Maybridge4_002870 CC1(C)c2cc(Cl)ccc2-n3c1cc(O)c(c4ccccc4)c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C11 compound treatment 0.298 0.0731 1.05 0.286 0.0578 0.97 1.425 0.9993 1019915 Maybridge4_002871 Cc1ccc(cc1)C(O)c2nccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C12 compound treatment 0.042 -0.183 -2.62 0.041 -0.187 -3.14 -4.0719 -0.9959 3064058 Maybridge4_002872 O/N=C/C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C13 compound treatment 0.246 0.0211 0.3 0.26 0.0318 0.53 0.5905 0.9636 3064059 Maybridge4_002873 CC(C)/C(=N/O)/c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C14 compound treatment 0.277 0.0521 0.75 0.239 0.0108 0.18 0.6548 0.854 1733383 Maybridge4_002874 CCCCC1(CO)C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C15 compound treatment 0.225 9.38E-5 0.0 0.192 -0.0362 -0.61 -0.4289 -0.7055 1134906 Maybridge4_002875 NC(=O)NC1C(Oc2ccccc2C1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C16 compound treatment 0.207 -0.0179 -0.26 0.212 -0.0162 -0.27 -0.3736 -0.9995 1708436 Maybridge4_002876 CSc1[nH]nc(NS(=O)(=O)c2ccc(Cl)cc2)c1c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C17 compound treatment 0.211 -0.0139 -0.2 0.198 -0.0302 -0.51 -0.4993 -0.9165 1325632 Maybridge4_002877 CCCCc1c(O)c2cccc3c4ccccc4n(c1=O)c32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C18 compound treatment 0.208 -0.0169 -0.24 0.262 0.0338 0.57 0.2299 0.373 3179393 Maybridge4_002878 O=C1NCCN1CC/N=C/c2ccc(C#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C19 compound treatment 0.217 -0.00791 -0.11 0.223 -0.00522 -0.09 -0.1419 -0.992 3064061 Maybridge4_002879 c1c2ccccc2c3ccc(oc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C20 compound treatment 0.218 -0.00691 -0.1 0.227 -0.00122 -0.02 -0.0843 -0.8358 1357662 Maybridge4_002880 CC(C)c1ccc(NN2C(=O)CC(C2=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C21 compound treatment 0.233 0.00809 0.12 0.227 -0.00122 -0.02 0.0674 0.5733 1704922 Maybridge4_002881 COc1cc(C)c2C3CCC4(C)C(O)CCC4C3CCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C22 compound treatment 0.255 0.0301 0.43 0.261 0.0328 0.55 0.6934 0.9926 1187010 Maybridge4_002882 Fc1ccc(C(=O)OCCn2ncc3ccccc3c2=O)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C23 mock treatment 0.268 0.0431 0.62 0.225 -0.00322 -0.05 0.3977 0.6427 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 C24 mock treatment 0.204 -0.0209 -0.3 0.179 -0.0492 -0.83 -0.7956 -0.9056 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D01 compound treatment 0.234 0.00909 0.13 0.205 -0.0232 -0.39 -0.1836 -0.4469 1248994 Maybridge4_002883 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)CSCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D02 compound treatment 0.218 -0.00691 -0.1 0.232 0.00378 0.06 -0.025 -0.2127 3064062 Maybridge4_002884 Cc1ccc(/N=C/2\SC3(CC3)C(=O)N2c4ccc(C)cc4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D03 compound treatment 0.245 0.0201 0.29 0.323 0.0948 1.59 1.3281 0.8216 3179394 Maybridge4_002885 Clc1cccc(c1)/C(=C/C=C/c2ccccc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D04 compound treatment 0.239 0.0141 0.2 0.247 0.0188 0.32 0.3654 0.9767 3064063 Maybridge4_002886 Clc1cccc(/N=C/2\SC3(CC3)C(=O)N2c4cccc(Cl)c4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D05 compound treatment 0.277 0.0521 0.75 0.227 -0.00122 -0.02 0.5124 0.6874 3179395 Maybridge4_002887 CCc1nn(C)c2c(=O)c(=O)c2n(C)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D06 compound treatment 0.166 -0.0589 -0.84 0.219 -0.00922 -0.15 -0.7052 -0.8232 3064064 Maybridge4_002888 CC1=NNC(=O)C1Oc2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D07 compound treatment 0.232 0.00709 0.1 0.297 0.0688 1.15 0.888 0.7663 3179396 Maybridge4_002889 CSC(=N)Nc1c(Cl)cccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D08 compound treatment 0.296 0.0711 1.02 0.282 0.0538 0.9 1.3573 0.9982 3179397 Maybridge4_002890 Cc1nc(nc(NCCNc2ccc(cn2)C(F)(F)F)c1Cl)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D09 compound treatment 0.283 0.0581 0.83 0.284 0.0558 0.94 1.2496 0.9982 3064065 Maybridge4_002891 Cc1cc(O)nc(SCC(=O)c2ccc(F)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D10 compound treatment 0.224 -9.06E-4 -0.01 0.242 0.0138 0.23 0.1544 0.6664 1513804 Maybridge4_002892 CCOC(=O)c1c(C)c(ccc1N(C)C)C2NC(=O)NC=C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D11 compound treatment 0.279 0.0541 0.77 0.282 0.0538 0.9 1.1854 0.9971 3064066 Maybridge4_002893 O=C(CSc1nc2ccccc2c(=O)n1Cc3ccco3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D12 compound treatment 0.274 0.0491 0.7 0.251 0.0228 0.38 0.7669 0.9592 3179501 Maybridge4_002894 CC(C)(C)c1ccc(cc1)/C(=N/O)/N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D13 compound treatment 0.259 0.0341 0.49 0.313 0.0848 1.42 1.351 0.8982 1669360 Maybridge4_002895 Clc1ccc(cc1)C(=O)Nc2cc(Cl)ccc2C(=O)OCC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D14 compound treatment 0.301 0.0761 1.09 0.294 0.0658 1.1 1.5503 1.0 3064067 Maybridge4_002896 CC(C)Nc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D15 compound treatment 0.281 0.0561 0.8 0.284 0.0558 0.94 1.2294 0.997 3064068 Maybridge4_002897 S=C(NC1CCCCC1)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D16 compound treatment 0.282 0.0571 0.82 0.283 0.0548 0.92 1.2276 0.9983 1715674 Maybridge4_002898 CN(C)c1nc(cc2C(=O)NC(=O)c21)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D17 compound treatment 0.286 0.0611 0.87 0.228 -2.19E-4 0.0 0.6153 0.7041 3064069 Maybridge4_002899 CN(C)/C(=N/c1cc(C)c(C)cc1C)/NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D18 compound treatment 0.252 0.0271 0.39 0.279 0.0508 0.85 0.8767 0.9364 3179502 Maybridge4_002900 COc1ccc(/N=c/2\scc(C)n2C(=O)c3ccccc3Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D19 compound treatment 0.221 -0.00391 -0.06 0.325 0.0968 1.62 1.1091 0.6824 1153907 Maybridge4_002901 COc1ccc(OCC(O)CNC(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D20 compound treatment 0.245 0.0201 0.29 0.255 0.0268 0.45 0.5211 0.9767 3064070 Maybridge4_002902 Clc1cccc(Cl)c1c2cc(on2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D21 compound treatment 0.277 0.0521 0.75 0.243 0.0148 0.25 0.7023 0.8943 1636805 Maybridge4_002903 Brc1ccc(OCC2CN(C(=O)O2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D22 compound treatment 0.24 0.0151 0.22 0.268 0.0398 0.67 0.6248 0.8904 3064071 Maybridge4_002904 CC(C)c1nc(/N=C/N(C)C)nc(=O)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D23 mock treatment 0.226 0.00109 0.02 0.28 0.0518 0.87 0.6256 0.7197 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 D24 mock treatment 0.245 0.0201 0.29 0.191 -0.0372 -0.62 -0.2385 -0.3468 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E01 compound treatment 0.249 0.0241 0.34 0.209 -0.0192 -0.32 0.0156 0.033 3179503 Maybridge4_002905 O=C(CSc1ccccn1)Nc2ccccc2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E02 compound treatment 0.253 0.0281 0.4 0.286 0.0578 0.97 0.9699 0.9239 3179504 Maybridge4_002906 N#CC1(N=C2C=CC=CN2N=C1c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E03 compound treatment 0.183 -0.0419 -0.6 0.234 0.00578 0.1 -0.3552 -0.585 3064072 Maybridge4_002907 O=C1OC2(CCCCC2)OC(=O)C1=Cc3ccoc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E04 compound treatment 0.231 0.00609 0.09 0.265 0.0368 0.62 0.4982 0.799 3179505 Maybridge4_002908 FC(F)(F)c1cc(nc(S/C=C/C(=O)c2ccccc2)c1C#N)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E05 compound treatment 0.266 0.0411 0.59 0.292 0.0638 1.07 1.1726 0.9601 3064073 Maybridge4_002909 CNS(=O)(=O)c1ccc(Br)cc1I 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E06 compound treatment 0.265 0.0401 0.57 0.271 0.0428 0.72 0.9132 0.9938 3179506 Maybridge4_002910 CC(=O)O[C@@H]1O[C@@H]2CO[C@H](O[C@H]2[C@H](OC(=O)C)[C@H]1OC(=O)C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E07 compound treatment 0.242 0.0171 0.24 0.291 0.0628 1.05 0.918 0.8486 1547193 Maybridge4_002911 CCNS(=O)(=O)c1cccc2c(N)cccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E08 compound treatment 0.289 0.0641 0.92 0.324 0.0958 1.61 1.785 0.9645 1448662 Maybridge4_002912 CCc1c(O)c(Cc2ccccc2)c(=O)n(c3nccs3)c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E09 compound treatment 0.287 0.0621 0.89 0.29 0.0618 1.04 1.3613 0.997 3179507 Maybridge4_002913 CCOC(=O)C(C#N)C1(C(=NN(C1=O)c2ccccc2)C)c3c(C)nn(c3O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E10 compound treatment 0.043 -0.182 -2.6 0.041 -0.187 -3.14 -4.0618 -0.9956 3064074 Maybridge4_002914 Fc1ccc(cc1)C(=O)/C=C/S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E11 compound treatment 0.273 0.0481 0.69 0.239 0.0108 0.18 0.6144 0.8637 1495930 Maybridge4_002915 CC(C)C(OC(=O)c1ccccc1)c2nccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E12 compound treatment 0.246 0.0211 0.3 0.281 0.0528 0.89 0.8398 0.8973 1260619 Maybridge4_002916 COC(=O)c1sc2c(C)cc(Cl)c(C)c2c1C(=O)Oc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E13 compound treatment 0.137 -0.0879 -1.26 0.157 -0.0712 -1.2 -1.7343 -0.9997 1268159 Maybridge4_002917 CCn1c(=O)cc(O)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E14 compound treatment 0.274 0.0491 0.7 0.28 0.0518 0.87 1.1111 0.9944 1134720 Maybridge4_002918 CCCCC1(COC(=O)c2ccc(OC)cc2)C(=O)N(N(C1=O)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E15 compound treatment 0.276 0.0511 0.73 0.288 0.0598 1.0 1.2263 0.9879 3063981 Maybridge4_002919 Clc1cc(Cl)c2c(=O)cc(oc2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E16 compound treatment 0.226 0.00109 0.02 0.275 0.0468 0.79 0.5663 0.7211 3063982 Maybridge4_002920 O=C(CSc1nc(SCC(=O)c2ccccc2)c3ccccc3n1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E17 compound treatment 0.116 -0.109 -1.56 0.12 -0.108 -1.82 -2.3859 -0.9971 1617223 Maybridge4_002921 Oc1c(Cc2ccccc2)c(=O)n3c4ccccc4c5cccc1c53 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E18 compound treatment 0.195 -0.0299 -0.43 0.261 0.0328 0.55 0.0866 0.1242 3063983 Maybridge4_002922 Clc1ccc(CCN2C(=O)CSC2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E19 compound treatment 0.224 -9.06E-4 -0.01 0.23 0.00178 0.03 0.012 0.3675 3179508 Maybridge4_002923 CCc1c(C)oc2cc3ccccc3c2c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E20 compound treatment 0.179 -0.0459 -0.66 0.253 0.0248 0.42 -0.1702 -0.219 1212790 Maybridge4_002924 O=C(CSc1nc2ccccc2c(=O)[nH]1)c3ccc(cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E21 compound treatment 0.222 -0.00291 -0.04 0.205 -0.0232 -0.39 -0.305 -0.7781 3179509 Maybridge4_002925 CC(OC(=O)C)C1CCC2C3CC[C@H]4CC(=O)CCC4(C)C3CCC12C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E22 compound treatment 0.258 0.0331 0.47 0.259 0.0308 0.52 0.7 0.999 1296117 Maybridge4_002926 O=C(OCCn1ncc2ccccc2c1=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E23 mock treatment 0.232 0.00709 0.1 0.242 0.0138 0.23 0.2353 0.9316 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 E24 mock treatment 0.222 -0.00291 -0.04 0.233 0.00478 0.08 0.0273 0.3026 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F01 compound treatment 0.272 0.0471 0.67 0.217 -0.0112 -0.19 0.3432 0.4906 1646144 Maybridge4_002927 CCCCC1(CN2CCN(Cc3ccccc3)CC2)C(=O)N(N(C1=O)c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F02 compound treatment 0.301 0.0761 1.09 0.269 0.0408 0.68 1.2536 0.975 1353488 Maybridge4_002928 OC(COc1ccc(F)cc1)CS(=O)(=O)Cc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F03 compound treatment 0.162 -0.0629 -0.9 0.186 -0.0422 -0.71 -1.1373 -0.993 3064021 Maybridge4_002929 CCc1ccc(cc1)/C(=C/C=C/c2ccccc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F04 compound treatment 0.242 0.0171 0.24 0.259 0.0308 0.52 0.5382 0.9416 1107774 Maybridge4_002930 Fc1ccc(NC(=S)C#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F05 compound treatment 0.201 -0.0239 -0.34 0.219 -0.00922 -0.15 -0.3512 -0.9357 1733993 Maybridge4_002931 CCc1cccc(CC)c1NC(=S)Nc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F06 compound treatment 0.306 0.0811 1.16 0.259 0.0308 0.52 1.1855 0.9336 3179510 Maybridge4_002932 FC(F)(F)c1ccc(cc1)C(=O)Nc2ccc(cc2)C3=NCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F07 compound treatment 0.217 -0.00791 -0.11 0.196 -0.0322 -0.54 -0.4623 -0.8369 3064024 Maybridge4_002933 Cc1cccc(Cl)c1NC(=S)NC(Cc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F08 compound treatment 0.324 0.0991 1.42 0.298 0.0698 1.17 1.8304 0.9955 1491434 Maybridge4_002934 C1CN(CCO1)c2nc(ns2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F09 compound treatment 0.281 0.0561 0.8 0.295 0.0668 1.12 1.3599 0.9866 1641045 Maybridge4_002935 CC(C)(CO)NC(=S)NCC1CCCO1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F10 compound treatment 0.34 0.115 1.65 0.306 0.0778 1.31 2.0872 0.9934 3179511 Maybridge4_002936 O/N=C/c1c(F)cccc1F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F11 compound treatment 0.317 0.0921 1.32 0.318 0.0898 1.51 1.997 0.9978 3179512 Maybridge4_002937 Sc1nc2ccccc2c(=O)n1c3ccc(Cl)c(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F12 compound treatment 0.31 0.0851 1.22 0.326 0.0978 1.64 2.0211 0.9892 3064025 Maybridge4_002938 Cc1cc(nn1c2ccccc2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F13 compound treatment 0.312 0.0871 1.25 0.343 0.115 1.93 2.2431 0.9777 3064027 Maybridge4_002939 Clc1ccc(cc1)C(=O)COC(=O)c2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F14 compound treatment 0.3 0.0751 1.07 0.337 0.109 1.83 2.0505 0.968 3179513 Maybridge4_002940 CC(C)Sc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F15 compound treatment 0.201 -0.0239 -0.34 0.296 0.0678 1.14 0.5626 0.4736 3179514 Maybridge4_002941 CCOC(=O)c1ccc(NC(=N)SCc2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F16 compound treatment 0.152 -0.0729 -1.04 0.205 -0.0232 -0.39 -1.013 -0.9099 3064028 Maybridge4_002942 Cc1onc(c1N)c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F17 compound treatment 0.303 0.0781 1.12 0.311 0.0828 1.39 1.7723 0.9941 3064029 Maybridge4_002943 Cc1cc(C)c(NC(=N)NN)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F18 compound treatment 0.275 0.0501 0.72 0.323 0.0948 1.59 1.6315 0.9351 3179515 Maybridge4_002944 COC(=O)c1c(noc1C(=O)NN)c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F19 compound treatment 0.285 0.0601 0.86 0.296 0.0678 1.14 1.4122 0.9904 1249379 Maybridge4_002945 COc1c(Cl)cccc1c2cn3ccc(C)cc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F20 compound treatment 0.161 -0.0639 -0.91 0.215 -0.0132 -0.22 -0.8032 -0.8539 1721352 Maybridge4_002946 Oc1nsc(Nc2ccccc2)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F21 compound treatment 0.274 0.0491 0.7 0.295 0.0668 1.12 1.2891 0.9746 1132779 Maybridge4_002947 COc1ccc(COCC(O)CS(=O)(=O)c2ccc(OC)c(OC)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F22 compound treatment 0.278 0.0531 0.76 0.267 0.0388 0.65 0.9973 0.9971 3064075 Maybridge4_002948 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F23 mock treatment 0.219 -0.00591 -0.08 0.229 7.81E-4 0.01 -0.0505 -0.5903 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 F24 mock treatment 0.192 -0.0329 -0.47 0.239 0.0108 0.18 -0.2049 -0.4063 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G01 compound treatment 0.213 -0.0119 -0.17 0.249 0.0208 0.35 0.1262 0.3252 1511541 Maybridge4_002949 Fc1ccc(NC(=O)C(=S)NC2CCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G02 compound treatment 0.232 0.00709 0.1 0.276 0.0478 0.8 0.6388 0.7903 1391130 Maybridge4_002950 Clc1ccc(Nc2nnc3c4ccccc4c5ccccc5c3n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G03 compound treatment 0.251 0.0261 0.37 0.292 0.0638 1.07 1.0209 0.9005 3179516 Maybridge4_002951 CC1C(=NN(C1=O)c2ccccc2)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G04 compound treatment 0.075 -0.15 -2.14 0.081 -0.147 -2.47 -3.2634 -0.9975 3179517 Maybridge4_002952 Cc1ccc2[nH]c(S/C=C/C(=O)c3ccccc3)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G05 compound treatment 0.268 0.0431 0.62 0.253 0.0248 0.42 0.73 0.9817 1247714 Maybridge4_002953 CNS(=O)(=O)c1c(I)ccc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G06 compound treatment 0.281 0.0561 0.8 0.293 0.0648 1.09 1.3362 0.9888 3179612 Maybridge4_002954 CC(=O)N1[C@H](SC(C)(C)[C@@H]1C(=O)O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G07 compound treatment 0.298 0.0731 1.05 0.334 0.106 1.78 1.9947 0.9681 1286617 Maybridge4_002955 COc1cc2OC(C)(C)CC(=O)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G08 compound treatment 0.322 0.0971 1.39 0.321 0.0928 1.56 2.0832 0.9984 3179613 Maybridge4_002956 CC(=O)OC(C#N)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G09 compound treatment 0.242 0.0171 0.24 0.307 0.0788 1.32 1.1079 0.8239 3064077 Maybridge4_002957 OC(=O)CCc1n[nH]c(=O)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G10 compound treatment 0.297 0.0721 1.03 0.349 0.121 2.03 2.1626 0.9509 3064078 Maybridge4_002958 Cc1c(cnn1c2ccccc2)c3nnnn3c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G11 compound treatment 0.321 0.0961 1.37 0.32 0.0918 1.54 2.0612 0.9984 3179614 Maybridge4_002959 O=S(CC#N)c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G12 compound treatment 0.307 0.0821 1.17 0.311 0.0828 1.39 1.8128 0.9965 3179615 Maybridge4_002960 FC(F)(F)c1cccc(OC(=O)c2cc3ccc4ccccc4c3s2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G13 compound treatment 0.289 0.0641 0.92 0.298 0.0698 1.17 1.4764 0.9927 3064081 Maybridge4_002961 CC(C)CC(C(O)c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G14 compound treatment 0.25 0.0251 0.36 0.198 -0.0302 -0.51 -0.1048 -0.1687 1388837 Maybridge4_002962 CCCCC1(COC(=O)Nc2cccc(Cl)c2)C(=O)N(N(C1=O)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G15 compound treatment 0.263 0.0381 0.54 0.314 0.0858 1.44 1.4033 0.9116 3064082 Maybridge4_002963 NC1=NC(C(N1)C(=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G16 compound treatment 0.232 0.00709 0.1 0.289 0.0608 1.02 0.7931 0.7736 3179616 Maybridge4_002964 CSc1nc2ccccc2c(=O)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G17 compound treatment 0.254 0.0291 0.42 0.297 0.0688 1.15 1.1106 0.905 3179617 Maybridge4_002965 O=c1ss/c(=N/Cc2ccccc2)/n1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G18 compound treatment 0.154 -0.0709 -1.01 0.162 -0.0662 -1.11 -1.5031 -0.999 3064083 Maybridge4_002966 S=C(NCC1CC1)NCc2csc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G19 compound treatment 0.255 0.0301 0.43 0.252 0.0238 0.4 0.5866 0.9993 1378931 Maybridge4_002967 C(NC1CCCCC1)C(CNC2CCCCC2)OCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G20 compound treatment 0.228 0.00309 0.04 0.234 0.00578 0.1 0.0999 0.9368 3064084 Maybridge4_002968 CC(C)(C)c1ccc(NC(=O)c2cnccn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G21 compound treatment 0.247 0.0221 0.32 0.219 -0.00922 -0.15 0.1141 0.3241 1050158 Maybridge4_002969 COc1ccc2C3CCC4(C)C(CCC4=O)C3CCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G22 compound treatment 0.082 -0.143 -2.04 0.085 -0.143 -2.4 -3.1451 -0.9967 1218870 Maybridge4_002970 O=C(Nc1cccnc1)c2cc3CCc4ccccc4-c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G23 mock treatment 0.201 -0.0239 -0.34 0.233 0.00478 0.08 -0.185 -0.5268 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 G24 mock treatment 0.212 -0.0129 -0.18 0.213 -0.0152 -0.26 -0.3112 -0.9873 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H01 compound treatment 0.207 -0.0179 -0.26 0.223 -0.00522 -0.09 -0.243 -0.8979 1264780 Maybridge4_002971 COc1ccc(NC(=O)C2CC(=C(C)CC2C(=O)O)C)c(n1)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H02 compound treatment 0.234 0.00909 0.13 0.262 0.0338 0.57 0.4929 0.8473 1569864 Maybridge4_002972 COc1ccc(COCC(O)CS(=O)(=O)Cc2ccc(C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H03 compound treatment 0.254 0.0291 0.42 0.291 0.0628 1.05 1.0394 0.9174 1169171 Maybridge4_002973 OCCNN1C(=O)c2cccc3cccc(C1=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H04 compound treatment 0.313 0.0881 1.26 0.273 0.0448 0.75 1.4225 0.9695 1600308 Maybridge4_002974 Cc1onc(c1C2=NCCO2)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H05 compound treatment 0.276 0.0511 0.73 0.307 0.0788 1.32 1.4518 0.9609 3179618 Maybridge4_002975 Cc1cccc(C)c1Nc2nc3c(C)cc(C)c(C)c3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H06 compound treatment 0.276 0.0511 0.73 0.247 0.0188 0.32 0.7397 0.9293 1417835 Maybridge4_002976 OC1CCCCC1S(=O)(=O)Cc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H07 compound treatment 0.261 0.0361 0.52 0.265 0.0368 0.62 0.8016 0.996 3064223 Maybridge4_002977 CCC(CO)NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H08 compound treatment 0.324 0.0991 1.42 0.332 0.104 1.74 2.2339 0.9948 3179619 Maybridge4_002978 Clc1ccc2oc(=S)n(Cc3ccccc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H09 compound treatment 0.273 0.0481 0.69 0.299 0.0708 1.19 1.3265 0.9663 3064225 Maybridge4_002979 CNC(=S)NCCc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H10 compound treatment 0.345 0.12 1.72 0.3 0.0718 1.2 2.0666 0.9849 3179620 Maybridge4_002980 O=C(OCc1ccc2OCOc2c1)OCc3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H11 compound treatment 0.33 0.105 1.5 0.276 0.0478 0.8 1.63 0.9567 3179621 Maybridge4_002981 Cc1cc(C)nc(NC(=S)c2ccc(NC(=O)/C=C/C(=O)O)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H12 compound treatment 0.326 0.101 1.45 0.317 0.0888 1.49 2.0761 0.9999 3064227 Maybridge4_002982 NC(=N)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H13 compound treatment 0.322 0.0971 1.39 0.344 0.116 1.94 2.3561 0.9864 1447884 Maybridge4_002983 COc1cccc(C(=O)OCC(=O)c2ccccc2)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H14 compound treatment 0.196 -0.0289 -0.41 0.185 -0.0432 -0.73 -0.8053 -0.9645 3179622 Maybridge4_002984 CCOC(=O)c1cc(nc(S)c1C#N)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H15 compound treatment 0.322 0.0971 1.39 0.273 0.0448 0.75 1.5135 0.9584 2077819 Maybridge4_002985 C[n+]1c(NC2CCCCC2)scc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H16 compound treatment 0.326 0.101 1.45 0.315 0.0868 1.46 2.0524 1.0 1009495 Maybridge4_002986 CC(C)(C)C1=CC(=O)C(=CC1=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H17 compound treatment 0.346 0.121 1.73 0.339 0.111 1.86 2.5395 0.9994 3179623 Maybridge4_002987 CCc1ccc(NC(=N)NC(=N)N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H18 compound treatment 0.286 0.0611 0.87 0.325 0.0968 1.62 1.7665 0.9577 1395086 Maybridge4_002988 Cc1nc(nc(O)c1Cl)C2(CC3CC4CC(C3)C2)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H19 compound treatment 0.241 0.0161 0.23 0.259 0.0308 0.52 0.5281 0.9337 1725570 Maybridge4_002989 CC(C)(C)C(=O)Nc1ccc(cc1)c2cc3cc(Cl)ccc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H20 compound treatment 0.123 -0.102 -1.46 0.136 -0.0922 -1.55 -2.1252 -0.9996 1661405 Maybridge4_002990 Cc1ccc(NC(=S)C(C#N)C(=O)N)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H21 compound treatment 0.286 0.0611 0.87 0.3 0.0718 1.2 1.4698 0.9876 1723738 Maybridge4_002991 Clc1ccc(N2C(CC(=O)NC2=S)c3ccccc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H22 compound treatment 0.263 0.0381 0.54 0.243 0.0148 0.25 0.5607 0.9366 3179624 Maybridge4_002992 OCc1noc(n1)c2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H23 mock treatment 0.209 -0.0159 -0.23 0.245 0.0168 0.28 0.0383 0.1057 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 H24 mock treatment 0.191 -0.0339 -0.48 0.222 -0.00622 -0.1 -0.4167 -0.8401 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I01 compound treatment 0.23 0.00509 0.07 0.266 0.0378 0.63 0.4999 0.7832 1401560 Maybridge4_002993 Clc1ccc(NC(=O)Nc2ccccc2)c(SCc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I02 compound treatment 0.236 0.0111 0.16 0.235 0.00678 0.11 0.1927 0.9867 1509609 Maybridge4_002994 CCSc1nnc2nc3c4ccccc4c5ccccc5c3nn12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I03 compound treatment 0.13 -0.0949 -1.36 0.132 -0.0962 -1.61 -2.1018 -0.9963 3179625 Maybridge4_002995 O=C/1N(N=C(Nc2ccccc2)\C1=C\Nc3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I04 compound treatment 0.048 -0.177 -2.53 0.051 -0.177 -2.97 -3.8925 -0.9968 3064579 Maybridge4_002996 Cn1cnnc1S/C=C/C(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I05 compound treatment 0.282 0.0571 0.82 0.305 0.0768 1.29 1.4887 0.9758 1063036 Maybridge4_002997 COc1cc(c(OC)cc1C(C)(C)C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I06 compound treatment 0.262 0.0371 0.53 0.273 0.0448 0.75 0.9066 0.9855 3179626 Maybridge4_002998 CSc1ccc(cc1)C2N[C@@H](C(=O)O)C(C)(C)S2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I07 compound treatment 0.257 0.0321 0.46 0.251 0.0228 0.38 0.595 0.9959 1248980 Maybridge4_002999 CCNS(=O)(=O)c1ccc(cc1)c2oc3cc(ccc3c2Cl)S(=O)(=O)NCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I08 compound treatment 0.28 0.0551 0.79 0.276 0.0478 0.8 1.1243 1.0 3064580 Maybridge4_003000 O=C/1N2CCCCSC2=N\C1=C\c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I09 compound treatment 0.34 0.115 1.65 0.299 0.0708 1.19 2.0041 0.9872 1326747 Maybridge4_003001 CN(C)c1ccc(cc1)C2Nc3[nH]nc(C)c3C4=C2C(=O)CCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I10 compound treatment 0.241 0.0161 0.23 0.218 -0.0102 -0.17 0.0415 0.1446 3179627 Maybridge4_003002 S=c1[nH]nc(c2ccccc2)c(c1C#N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I11 compound treatment 0.318 0.0931 1.33 0.294 0.0658 1.1 1.7223 0.9957 3063889 Maybridge4_003003 COc1ccc2CC(=O)CCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I12 compound treatment 0.331 0.106 1.52 0.323 0.0948 1.59 2.1979 0.9997 1333404 Maybridge4_003004 CCCC1C2C(ON1c3ccc(Cl)c(Cl)c3)C(=O)N(C2=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I13 compound treatment 0.314 0.0891 1.27 0.295 0.0668 1.12 1.6937 0.998 3063891 Maybridge4_003005 CC(C)CC(C(=O)c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I14 compound treatment 0.311 0.0861 1.23 0.279 0.0508 0.85 1.4734 0.9838 1366549 Maybridge4_003006 Clc1cc(Cl)cc(c1)N2C(=O)CC(C2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I15 compound treatment 0.318 0.0931 1.33 0.274 0.0458 0.77 1.4849 0.9659 1552090 Maybridge4_003007 O=c1c(coc2ccccc12)c3nnn[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I16 compound treatment 0.311 0.0861 1.23 0.266 0.0378 0.63 1.3192 0.9524 1232818 Maybridge4_003008 CSc1nc2ccccc2c(=O)n1CC(=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I17 compound treatment 0.319 0.0941 1.35 0.252 0.0238 0.4 1.2339 0.879 3063892 Maybridge4_003009 COc1cc2ccc(=O)oc2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I18 compound treatment 0.307 0.0821 1.17 0.298 0.0698 1.17 1.6585 1.0 3063893 Maybridge4_003010 CN/1\C(=N/C(=O)C)\NC(=O)\C1=C/c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I19 compound treatment 0.263 0.0381 0.54 0.281 0.0528 0.89 1.0117 0.9728 1630014 Maybridge4_003011 NC(CCc1ccccc1Cl)c2ccc3OCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I20 compound treatment 0.27 0.0451 0.65 0.209 -0.0192 -0.32 0.228 0.3162 1530797 Maybridge4_003012 CCC1(CC)COC2(OC1)C(=O)Nc3ccc(F)cc32 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I21 compound treatment 0.214 -0.0109 -0.16 0.223 -0.00522 -0.09 -0.1722 -0.9628 3063895 Maybridge4_003013 Cc1cc(oc2cc3ccccc3c12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I22 compound treatment 0.251 0.0261 0.37 0.259 0.0308 0.52 0.6292 0.9873 3179717 Maybridge4_003014 Cc1cccc(c1)n2ncc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I23 mock treatment 0.215 -0.00991 -0.14 0.224 -0.00422 -0.07 -0.1503 -0.9486 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 I24 mock treatment 0.213 -0.0119 -0.17 0.201 -0.0272 -0.46 -0.4435 -0.9096 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J01 compound treatment 0.223 -0.00191 -0.03 0.224 -0.00422 -0.07 -0.0693 -0.914 1715355 Maybridge4_003015 OC(=O)COCC(=O)Nc1cnccn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J02 compound treatment 0.224 -9.06E-4 -0.01 0.245 0.0168 0.28 0.19 0.6739 1137874 Maybridge4_003016 Cc1cccc(C)c1n2c(n[nH]c2=S)C3CC4CCC3O4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J03 compound treatment 0.238 0.0131 0.19 0.264 0.0358 0.6 0.5571 0.8856 1593696 Maybridge4_003017 CN(C)N1C(=O)c2cccc3cccc(C1=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J04 compound treatment 0.226 0.00109 0.02 0.258 0.0298 0.5 0.3645 0.7289 3063897 Maybridge4_003018 CC(=O)Nc1ccc(Br)c(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J05 compound treatment 0.233 0.00809 0.12 0.223 -0.00522 -0.09 0.0199 0.1373 1249809 Maybridge4_003019 CC(C)c1ccc(Nc2nnns2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J06 compound treatment 0.271 0.0461 0.66 0.303 0.0748 1.26 1.3537 0.9548 1591476 Maybridge4_003020 CCN(CC)c1nc2ccccc2c(=O)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J07 compound treatment 0.27 0.0451 0.65 0.248 0.0198 0.33 0.6909 0.9523 1593840 Maybridge4_003021 CCN(CC)C(=S)Oc1ccccc1C(=O)Nc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J08 compound treatment 0.314 0.0891 1.27 0.269 0.0408 0.68 1.3851 0.9575 3063932 Maybridge4_003022 Clc1cc(Cl)cc(Oc2nc(ns2)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J09 compound treatment 0.301 0.0761 1.09 0.282 0.0538 0.9 1.4079 0.9957 1389101 Maybridge4_003023 OC(=O)CCC(=O)Nc1cccc(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J10 compound treatment 0.215 -0.00991 -0.14 0.243 0.0148 0.25 0.0752 0.2633 3063933 Maybridge4_003024 Cc1nc(S)c(C#N)c(C)c1CCC#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J11 compound treatment 0.27 0.0451 0.65 0.301 0.0728 1.22 1.3199 0.9555 3179718 Maybridge4_003025 Cc1nnc(Nc2cccc(Cl)c2C)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J12 compound treatment 0.13 -0.0949 -1.36 0.088 -0.14 -2.35 -2.624 -0.9658 3063934 Maybridge4_003026 CNC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J13 compound treatment 0.063 -0.162 -2.32 0.061 -0.167 -2.81 -3.6221 -0.9954 1446584 Maybridge4_003027 Cc1cc(Br)ccc1NC(=S)Nc2cccc(NC(=O)c3ccccc3O)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J14 compound treatment 0.268 0.0431 0.62 0.293 0.0648 1.09 1.2047 0.9639 3179719 Maybridge4_003028 CCOC(=O)c1cc(nc(O)c1C#N)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J15 compound treatment 0.294 0.0691 0.99 0.331 0.103 1.73 1.9186 0.9651 3063936 Maybridge4_003029 O=c1cc(nc2scc(c3ccccc3)n12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J16 compound treatment 0.316 0.0911 1.3 0.259 0.0308 0.52 1.2867 0.918 3179720 Maybridge4_003030 CCOC(=O)NC(=S)Nc1ccc(cc1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J17 compound treatment 0.29 0.0651 0.93 0.287 0.0588 0.99 1.356 0.9996 3063937 Maybridge4_003031 Cc1nc(S)nc(O)c1CC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J18 compound treatment 0.268 0.0431 0.62 0.287 0.0588 0.99 1.1335 0.9744 3179721 Maybridge4_003032 Sc1nnc([nH]1)C2(CC3CC4CC(C3)C2)C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J19 compound treatment 0.317 0.0921 1.32 0.306 0.0778 1.31 1.8546 1.0 3063939 Maybridge4_003033 COc1ccc(CCn2c(=S)[nH]c3cc(ccc23)C(F)(F)F)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J20 compound treatment 0.3 0.0751 1.07 0.245 0.0168 0.28 0.9587 0.8633 3179722 Maybridge4_003034 N#Cc1ccc(cc1)C2SCCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J21 compound treatment 0.312 0.0871 1.25 0.269 0.0408 0.68 1.3649 0.9602 3179723 Maybridge4_003035 FC(F)(F)c1cccc(c1)N2C(CC(=O)NC2=S)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J22 compound treatment 0.258 0.0331 0.47 0.229 7.81E-4 0.01 0.344 0.7264 3063940 Maybridge4_003036 Oc1nnc(n2cccc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J23 mock treatment 0.269 0.0441 0.63 0.233 0.00478 0.08 0.5027 0.7907 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 J24 mock treatment 0.218 -0.00691 -0.1 0.234 0.00578 0.1 -0.0012 -0.0089 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K01 compound treatment 0.234 0.00909 0.13 0.275 0.0468 0.79 0.6472 0.8132 1466072 Maybridge4_003037 CC(C)(C)c1ccc(CSCC(=O)Nc2ccccc2C#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K02 compound treatment 0.22 -0.00491 -0.07 0.258 0.0298 0.5 0.3038 0.6019 1417054 Maybridge4_003038 COc1ccc(Cc2nc(n[nH]c2=S)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K03 compound treatment 0.314 0.0891 1.27 0.306 0.0778 1.31 1.8242 0.9999 1566854 Maybridge4_003039 Cc1ccc(C(=O)Nc2ccccc2)c(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K04 compound treatment 0.251 0.0261 0.37 0.256 0.0278 0.47 0.5936 0.9939 1404328 Maybridge4_003040 CCC1(CC)C(=O)c2cc3ccccc3cc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K05 compound treatment 0.254 0.0291 0.42 0.261 0.0328 0.55 0.6833 0.9905 1489684 Maybridge4_003041 CNC(=O)c1ccccc1Sc2ccccc2C(=O)NC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K06 compound treatment 0.277 0.0521 0.75 0.283 0.0548 0.92 1.177 0.9946 3179724 Maybridge4_003042 NC(=N)/N=C(\N)/Nc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K07 compound treatment 0.276 0.0511 0.73 0.288 0.0598 1.0 1.2263 0.9879 3063986 Maybridge4_003043 COC(=O)c1c2ccccc2c(C)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K08 compound treatment 0.333 0.108 1.55 0.288 0.0598 1.0 1.8028 0.9781 3179725 Maybridge4_003044 COc1ccc(/C=C\2/N=C3SC(C)C(=O)N3C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K09 compound treatment 0.306 0.0811 1.16 0.281 0.0528 0.89 1.4466 0.9911 3063988 Maybridge4_003045 C/C(=C\c1ccccc1)/C(=N/O)/C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K10 compound treatment 0.281 0.0561 0.8 0.288 0.0598 1.0 1.2768 0.9939 3179726 Maybridge4_003046 N#C/C(=C\C(=C\N1CCOCC1)\c2ccccc2)/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K11 compound treatment 0.31 0.0851 1.22 0.282 0.0538 0.9 1.4989 0.9892 1700846 Maybridge4_003047 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)n2ccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K12 compound treatment 0.326 0.101 1.45 0.227 -0.00122 -0.02 1.008 0.697 1550463 Maybridge4_003048 O=C1CSCC(=O)N1c2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K13 compound treatment 0.264 0.0391 0.56 0.26 0.0318 0.53 0.7726 0.9997 1209004 Maybridge4_003049 COC(=O)C1=C(O)C2(CC(=C(O)C(C1)(C2)C(=O)O)C(=O)OC)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K14 compound treatment 0.319 0.0941 1.35 0.315 0.0868 1.46 1.9816 0.9992 3063990 Maybridge4_003050 FC(F)(F)Oc1ccc(/N=c/2\[nH]c(=O)c3ccccc3o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K15 compound treatment 0.253 0.0281 0.4 0.298 0.0698 1.17 1.1123 0.8983 3179727 Maybridge4_003051 FC(F)(F)c1ccc(Oc2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K16 compound treatment 0.309 0.0841 1.2 0.224 -0.00422 -0.07 0.8005 0.6643 3063992 Maybridge4_003052 COC(=O)/C=C\1/NCC(CNC1=O)OC(=O)c2ccc(cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K17 compound treatment 0.235 0.0101 0.14 0.267 0.0388 0.65 0.5623 0.8435 1628564 Maybridge4_003053 C1Cc2nc(ccc2-c3ccccc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K18 compound treatment 0.245 0.0201 0.29 0.259 0.0308 0.52 0.5685 0.9617 3179728 Maybridge4_003054 CC1CC(CC(C)(C)C1)NC(=S)Nc2ccc(I)cc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K19 compound treatment 0.268 0.0431 0.62 0.267 0.0388 0.65 0.8961 0.9996 3063993 Maybridge4_003055 Cn1c(=O)n(C)c2ncn(CCCCn3cnc4n(C)c(=O)n(C)c(=O)c34)c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K20 compound treatment 0.257 0.0321 0.46 0.214 -0.0142 -0.24 0.1559 0.3012 3179729 Maybridge4_003056 CSc1cccc(c1)N2C(=O)C3CC=C(C)CC3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K21 compound treatment 0.226 0.00109 0.02 0.253 0.0248 0.42 0.3052 0.7332 1568172 Maybridge4_003057 OCC(C(O)c1ccccc1)N2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K22 compound treatment 0.206 -0.0189 -0.27 0.159 -0.0692 -1.16 -1.0127 -0.849 1396421 Maybridge4_003058 NNC(=O)c1cc2CCc3ccccc3-c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K23 mock treatment 0.238 0.0131 0.19 0.184 -0.0442 -0.74 -0.3924 -0.5126 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 K24 mock treatment 0.225 9.38E-5 0.0 0.214 -0.0142 -0.24 -0.1678 -0.7031 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L01 compound treatment 0.229 0.00409 0.06 0.232 0.00378 0.06 0.0863 0.9992 3179730 Maybridge4_003059 Cc1c(sc2nc(nn12)C(F)(F)F)C(=O)Cc3c(O)c4ccccc4oc3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L02 compound treatment 0.227 0.00209 0.03 0.282 0.0538 0.9 0.6595 0.7302 3063994 Maybridge4_003060 FC(F)(F)c1cc(cc(c1)C(F)(F)F)N2C(=O)CC3(CCCC3)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L03 compound treatment 0.289 0.0641 0.92 0.273 0.0448 0.75 1.1797 0.9951 3179731 Maybridge4_003061 CCOc1ccc(Br)cc1/C=N/c2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L04 compound treatment 0.216 -0.00891 -0.13 0.262 0.0338 0.57 0.3108 0.5349 1505741 Maybridge4_003062 CC(C)c1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)CCC3=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L05 compound treatment 0.256 0.0311 0.44 0.206 -0.0222 -0.37 0.0508 0.0875 3064031 Maybridge4_003063 Nc1ccccc1NC(=S)Nc2ccccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L06 compound treatment 0.284 0.0591 0.85 0.258 0.0298 0.5 0.9511 0.9686 3064032 Maybridge4_003064 CN(C)c1nc2ccccc2c(=O)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L07 compound treatment 0.25 0.0251 0.36 0.221 -0.00722 -0.12 0.1681 0.4438 3179732 Maybridge4_003065 CCN(CC)C(=S)Oc1ccc(I)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L08 compound treatment 0.321 0.0961 1.37 0.229 7.81E-4 0.01 0.9812 0.7138 3179733 Maybridge4_003066 FC(F)(F)c1cc(Cl)c2nc(cn2c1)C(=O)NC(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L09 compound treatment 0.256 0.0311 0.44 0.268 0.0398 0.67 0.7866 0.9805 1015049 Maybridge4_003067 CC(=O)Nc1ccc(Cl)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L10 compound treatment 0.287 0.0621 0.89 0.253 0.0248 0.42 0.9221 0.9403 3064035 Maybridge4_003068 CCOC(=O)/C(=N/O)/C1=NN=C(N)SC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L11 compound treatment 0.239 0.0141 0.2 0.271 0.0428 0.72 0.6503 0.8719 3179734 Maybridge4_003069 CC(C)Nc1nnc(C)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L12 compound treatment 0.33 0.105 1.5 0.263 0.0348 0.58 1.4757 0.9151 3064037 Maybridge4_003070 CN(C)C(=O)Nc1cc(C)n(n1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L13 compound treatment 0.317 0.0921 1.32 0.264 0.0358 0.6 1.3561 0.9367 3179735 Maybridge4_003071 Cc1cccc(C)c1/N=C/2\NC(C)(CO)CS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L14 compound treatment 0.308 0.0831 1.19 0.261 0.0328 0.55 1.2295 0.9387 1316254 Maybridge4_003072 Cc1cc2C(=O)NC(=O)c2c(Sc3ccc(Cl)cc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L15 compound treatment 0.279 0.0541 0.77 0.237 0.00878 0.15 0.6513 0.8269 3064038 Maybridge4_003073 Clc1ccc(cc1)c2csc3nc(cc(=O)n23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L16 compound treatment 0.326 0.101 1.45 0.278 0.0498 0.84 1.6133 0.966 1158628 Maybridge4_003074 CNC(=O)Nc1ccc(cc1Br)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L17 compound treatment 0.283 0.0581 0.83 0.236 0.00778 0.13 0.6799 0.8083 3064039 Maybridge4_003075 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2c(S)nc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L18 compound treatment 0.293 0.0681 0.97 0.256 0.0278 0.47 1.0184 0.9431 1188106 Maybridge4_003076 Clc1cccc(Cl)c1c2nscc2NC(=O)NN3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L19 compound treatment 0.289 0.0641 0.92 0.271 0.0428 0.72 1.156 0.9927 3064040 Maybridge4_003077 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2cn3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L20 compound treatment 0.113 -0.112 -1.6 0.053 -0.175 -2.94 -3.2114 -0.9591 3178150 Maybridge4_003078 CNC(=O)Oc1ccc(cc1)c2nc(CSc3ccc(Cl)cc3)cs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L21 compound treatment 0.288 0.0631 0.9 0.217 -0.0112 -0.19 0.505 0.5478 1216087 Maybridge4_003079 CC(C)c1ccc(NCC(O)CSc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L22 compound treatment 0.306 0.0811 1.16 0.286 0.0578 0.97 1.506 0.996 3064086 Maybridge4_003080 OCc1nc(cs1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L23 mock treatment 0.25 0.0251 0.36 0.287 0.0588 0.99 0.9514 0.9062 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 L24 mock treatment 0.22 -0.00491 -0.07 0.237 0.00878 0.15 0.0546 0.3344 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M01 compound treatment 0.279 0.0541 0.77 0.317 0.0888 1.49 1.6008 0.9534 1228182 Maybridge4_003081 O=C(Nc1ccc2OCOc2c1)C(=S)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M02 compound treatment 0.307 0.0821 1.17 0.282 0.0538 0.9 1.4686 0.9916 3064088 Maybridge4_003082 CCOC(=O)CSc1nnc(c2ccccc2)c(=O)n1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M03 compound treatment 0.265 0.0401 0.57 0.261 0.0328 0.55 0.7946 0.9998 3178151 Maybridge4_003083 CC1(C)OC(=O)C(=Cc2ccoc2)C(=O)O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M04 compound treatment 0.296 0.0711 1.02 0.286 0.0578 0.97 1.4048 0.9997 3178152 Maybridge4_003084 C[C@]1(O)CCC2C3CC[C@H]4CC(=O)/C(=C/c5ccccc5)/CC4(C)C3CCC21C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M05 compound treatment 0.28 0.0551 0.79 0.28 0.0518 0.87 1.1718 0.9988 2077623 Maybridge4_003085 CNC(=O)c1ccccc1[S+]2N(C)C(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M06 compound treatment 0.235 0.0101 0.14 0.225 -0.00322 -0.05 0.0639 0.4145 3064090 Maybridge4_003086 Cc1ccc(cc1)C(=O)/C=C/Nc2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M07 compound treatment 0.23 0.00509 0.07 0.231 0.00278 0.05 0.0845 0.9768 3064091 Maybridge4_003087 FC(F)(F)C(=O)N1CCCc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M08 compound treatment 0.285 0.0601 0.86 0.271 0.0428 0.72 1.1155 0.996 3178153 Maybridge4_003088 CN(C)/C=C/C=C/1\N=C(OC1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M09 compound treatment 0.233 0.00809 0.12 0.235 0.00678 0.11 0.1623 1.0 1045240 Maybridge4_003089 O(c1ccccc1)c2nc(Oc3ccccc3)nc(Oc4ccccc4)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M10 compound treatment 0.265 0.0401 0.57 0.247 0.0188 0.32 0.6284 0.9603 1341049 Maybridge4_003090 Oc1c(Cc2ccccc2)c(=O)n(c3ccccc3)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M11 compound treatment 0.268 0.0431 0.62 0.242 0.0138 0.23 0.5994 0.9105 1250198 Maybridge4_003091 CCN1c2cc(NC(=O)CC)ccc2C(C)CC1(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M12 compound treatment 0.278 0.0531 0.76 0.261 0.0328 0.55 0.9261 0.9875 1276296 Maybridge4_003092 COC(=O)c1cc(=O)n2CCSc2c1C(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M13 compound treatment 0.2 -0.0249 -0.36 0.21 -0.0182 -0.31 -0.4681 -0.9971 1660543 Maybridge4_003093 CCC(C)c1cc(N)nc2nc3ccccc3n12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M14 compound treatment 0.278 0.0531 0.76 0.275 0.0468 0.79 1.0922 0.9999 1341769 Maybridge4_003094 Fc1ccc(cc1)N2C(=O)CC(C2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M15 compound treatment 0.225 9.38E-5 0.0 0.212 -0.0162 -0.27 -0.1915 -0.7036 3178154 Maybridge4_003095 CCOC(=O)CCc1c(CC(=O)OCC)c[nH]c1/C=N/O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M16 compound treatment 0.243 0.0181 0.26 0.157 -0.0712 -1.2 -0.6622 -0.5415 3064093 Maybridge4_003096 OC(=O)c1ccccc1SC(CC(=O)c2ccc(F)cc2)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M17 compound treatment 0.272 0.0471 0.67 0.231 0.00278 0.05 0.5093 0.7543 3178155 Maybridge4_003097 Clc1ccccc1N/C=C\C2=NN=NC2c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M18 compound treatment 0.287 0.0621 0.89 0.235 0.00678 0.11 0.7085 0.7913 3064095 Maybridge4_003098 CN(C)NC(=S)NCc1ccc(F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M19 compound treatment 0.133 -0.0919 -1.31 0.119 -0.109 -1.83 -2.2258 -0.9867 3178156 Maybridge4_003099 CC(=O)OC1CCC2C3CC[C@H]4C[C@@H]5C[C@@H]5[C@H](O)C4(C)C3CCC12C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M20 compound treatment 0.233 0.00809 0.12 0.24 0.0118 0.2 0.2217 0.9675 1273753 Maybridge4_003100 S=C(N1CCN(Cc2ccccc2)CC1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M21 compound treatment 0.259 0.0341 0.49 0.262 0.0338 0.57 0.7458 0.9972 3064162 Maybridge4_003101 CCOC(=O)/N=C(/c1ccc(Cl)cc1)\c2cc3ccccc3cn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M22 compound treatment 0.258 0.0331 0.47 0.286 0.0578 0.97 1.0205 0.9456 1623253 Maybridge4_003102 CCOC(=O)CC(Sc1ccccc1N)c2cc(OC)c(OC)c(OC)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M23 mock treatment 0.261 0.0361 0.52 0.239 0.0108 0.18 0.493 0.9012 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 M24 mock treatment 0.271 0.0461 0.66 0.262 0.0338 0.57 0.8671 0.9972 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N01 compound treatment 0.238 0.0131 0.19 0.261 0.0328 0.55 0.5215 0.8972 3178157 Maybridge4_003103 CN(C)c1ccc(/C=C(\C#N)/c2ccc(C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N02 compound treatment 0.243 0.0181 0.26 0.202 -0.0262 -0.44 -0.1282 -0.251 3178158 Maybridge4_003104 FC(F)(F)Oc1ccc(OCc2n[nH]c(=S)o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N03 compound treatment 0.23 0.00509 0.07 0.252 0.0238 0.4 0.3338 0.8226 1090055 Maybridge4_003105 CC(C)c1ccc(cc1)N2Cc3cc(ccc3N=C2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N04 compound treatment 0.255 0.0301 0.43 0.266 0.0378 0.63 0.7528 0.9822 3064190 Maybridge4_003106 FC(F)(F)Oc1ccc(OC(=O)C2=Cc3cc(Cl)ccc3OC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N05 compound treatment 0.267 0.0421 0.6 0.27 0.0418 0.7 0.9216 0.9971 3178159 Maybridge4_003107 Cc1cc(Cl)ccc1NC(=N)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N06 compound treatment 0.276 0.0511 0.73 0.285 0.0568 0.95 1.1907 0.9914 3178160 Maybridge4_003108 FC(F)(F)c1cnc(NCCNC(=O)C(F)(F)Sc2ccccc2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N07 compound treatment 0.296 0.0711 1.02 0.254 0.0258 0.43 1.025 0.9275 3064194 Maybridge4_003109 CCN(CC)C(=S)Oc1ccc(C#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N08 compound treatment 0.262 0.0371 0.53 0.249 0.0208 0.35 0.6218 0.9793 3064195 Maybridge4_003110 CC(C)(C)CC(C)(C)NC(=O)c1cccc(/N=C/c2ccccc2O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N09 compound treatment 0.125 -0.0999 -1.43 0.142 -0.0862 -1.45 -2.0337 -1.0 1463402 Maybridge4_003111 CCc1ccccc1NC(=S)Nc2ccc(Oc3ccc(Cl)cc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N10 compound treatment 0.219 -0.00591 -0.08 0.222 -0.00622 -0.1 -0.1335 -0.9945 3064198 Maybridge4_003112 Clc1ccc(SC(=S)NC2CCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N11 compound treatment 0.278 0.0531 0.76 0.273 0.0448 0.75 1.0685 1.0 1288025 Maybridge4_003113 Clc1ccc(cc1)C(=O)COC(=O)c2ccccc2NCc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N12 compound treatment 0.255 0.0301 0.43 0.249 0.0208 0.35 0.551 0.9946 3064199 Maybridge4_003114 OC(=O)c1cc(O)nc2c(cccc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N13 compound treatment 0.232 0.00709 0.1 0.215 -0.0132 -0.22 -0.0851 -0.349 3178161 Maybridge4_003115 CC1CCCC(C)N1C(=S)NCCCN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N14 compound treatment 0.308 0.0831 1.19 0.264 0.0358 0.6 1.2651 0.95 3178162 Maybridge4_003116 CCOC(=O)c1cc(nc(OC(=O)N(C)C)c1C#N)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N15 compound treatment 0.247 0.0221 0.32 0.199 -0.0292 -0.49 -0.1233 -0.2114 3064201 Maybridge4_003117 COc1ccc(/N=C/2\SCC(=O)N2CCc3ccc(OC)c(OC)c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N16 compound treatment 0.285 0.0601 0.86 0.282 0.0538 0.9 1.2461 0.9997 3178163 Maybridge4_003118 Clc1cn(CCC#N)cc(Cl)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N17 compound treatment 0.261 0.0361 0.52 0.311 0.0828 1.39 1.3475 0.9091 3064203 Maybridge4_003119 CC1=NNC(=O)C1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N18 compound treatment 0.219 -0.00591 -0.08 0.276 0.0478 0.8 0.5073 0.6291 1440599 Maybridge4_003120 CCOC(=O)Cn1c(noc1=O)c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N19 compound treatment 0.239 0.0141 0.2 0.203 -0.0252 -0.42 -0.1568 -0.3343 3178164 Maybridge4_003121 Cc1cc(C)c(OC(=O)/C=C/c2cccs2)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N20 compound treatment 0.283 0.0581 0.83 0.269 0.0408 0.68 1.0716 0.9954 3064205 Maybridge4_003122 CSc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(F)(F)F)nc(n1)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N21 compound treatment 0.278 0.0531 0.76 0.217 -0.0112 -0.19 0.4039 0.5162 1468063 Maybridge4_003123 CC(C)c1ccc(NCC(O)COc2ccc(Cl)c(Cl)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N22 compound treatment 0.308 0.0831 1.19 0.286 0.0578 0.97 1.5262 0.9949 3064206 Maybridge4_003124 O=C1CNC(=S)N1CCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N23 mock treatment 0.237 0.0121 0.17 0.231 0.00278 0.05 0.1553 0.8669 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 N24 mock treatment 0.231 0.00609 0.09 0.24 0.0118 0.2 0.2015 0.9322 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O01 compound treatment 0.267 0.0421 0.6 0.253 0.0248 0.42 0.7199 0.9837 1118081 Maybridge4_003125 NNC(=O)CNc1ccc2OCOc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O02 compound treatment 0.278 0.0531 0.76 0.255 0.0268 0.45 0.8548 0.9687 3178165 Maybridge4_003126 CCOC(=O)c1cnc(S/C=C/C(=O)c2ccc(C)cc2)nc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O03 compound treatment 0.281 0.0561 0.8 0.313 0.0848 1.42 1.5735 0.9632 1121873 Maybridge4_003127 OC(=O)c1ccccc1S(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O04 compound treatment 0.244 0.0191 0.27 0.261 0.0328 0.55 0.5822 0.9478 3064232 Maybridge4_003128 Clc1ccc(cc1)C(=O)O/C=C/C(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O05 compound treatment 0.314 0.0891 1.27 0.264 0.0358 0.6 1.3258 0.9411 3178166 Maybridge4_003129 CNC(=O)c1cccc2cccc(Br)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O06 compound treatment 0.248 0.0231 0.33 0.256 0.0278 0.47 0.5633 0.9857 3178167 Maybridge4_003130 COc1ccc(cc1)C(=O)/C=C/Nc2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O07 compound treatment 0.284 0.0591 0.85 0.263 0.0348 0.58 1.0105 0.9837 3064235 Maybridge4_003131 N#CN=C(NC1CCCCC1)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O08 compound treatment 0.201 -0.0239 -0.34 0.192 -0.0362 -0.61 -0.6716 -0.963 3178168 Maybridge4_003132 Fc1ccc(cc1)C(=O)/C=C/Sc2nc3cc(Cl)ccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O09 compound treatment 0.248 0.0231 0.33 0.172 -0.0562 -0.94 -0.4336 -0.4338 1715504 Maybridge4_003133 CN1C(=O)C(Cc2ccccc2)(c3ccccc13)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O10 compound treatment 0.196 -0.0289 -0.41 0.231 0.00278 0.05 -0.2594 -0.6233 1565110 Maybridge4_003134 CN(C)C(=O)Oc1cc(C)n(C)c(=O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O11 compound treatment 0.309 0.0841 1.2 0.246 0.0178 0.3 1.0616 0.8566 3064240 Maybridge4_003135 C/C=C(\C(=N\O)\C)/c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O12 compound treatment 0.284 0.0591 0.85 0.253 0.0248 0.42 0.8918 0.9467 1124022 Maybridge4_003136 CC(=O)n1c(cc(c(C#N)c1=O)c2ccc(C)cc2)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O13 compound treatment 0.215 -0.00991 -0.14 0.214 -0.0142 -0.24 -0.2689 -0.969 1736617 Maybridge4_003137 COc1ccc(cc1)c2nc([nH]c(=O)c2C#N)N(C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O14 compound treatment 0.042 -0.183 -2.62 0.063 -0.165 -2.77 -3.8108 -0.9996 3178250 Maybridge4_003138 FC(F)(F)c1ccc(/C=C(\C#N)/c2c[nH]c3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O15 compound treatment 0.271 0.0461 0.66 0.199 -0.0292 -0.49 0.1194 0.1453 1429244 Maybridge4_003139 CCOC(=O)Cc1c(C)[nH]c(C(=O)OCC)c1CC(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O16 compound treatment 0.247 0.0221 0.32 0.125 -0.103 -1.73 -1.0015 -0.5687 1373405 Maybridge4_003140 CC(=O)SC1CC(=O)N(C1=O)c2ccc(cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O17 compound treatment 0.229 0.00409 0.06 0.194 -0.0342 -0.57 -0.3647 -0.6317 3178251 Maybridge4_003141 O=C(C/C(=C\1/Cc2ccccc2C1=O)/c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O18 compound treatment 0.238 0.0131 0.19 0.222 -0.00622 -0.1 0.0586 0.2734 3064242 Maybridge4_003142 CN(C)NC(=S)NCc1ccc(C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O19 compound treatment 0.271 0.0461 0.66 0.198 -0.0302 -0.51 0.1076 0.1293 3178252 Maybridge4_003143 CCOC(=O)OC1CCC2C3CCC4=CC(=O)C(=C)CC4(C)C3CCC12C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O20 compound treatment 0.261 0.0361 0.52 0.216 -0.0122 -0.21 0.22 0.3961 1442612 Maybridge4_003144 Cc1cc(NCn2ncc3ccccc3c2=O)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O21 compound treatment 0.254 0.0291 0.42 0.199 -0.0292 -0.49 -0.0525 -0.0816 3178253 Maybridge4_003145 Brc1ccc(cc1)c2cnc(/C=C/C=C/N3CCOCC3)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O22 compound treatment 0.252 0.0271 0.39 0.198 -0.0302 -0.51 -0.0846 -0.1325 1286622 Maybridge4_003146 O=C1c2ccccc2-c3c1c4ccccc4c(=O)n3CC5CC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O23 mock treatment 0.221 -0.00391 -0.06 0.214 -0.0142 -0.24 -0.2083 -0.8497 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 O24 mock treatment 0.185 -0.0399 -0.57 0.215 -0.0132 -0.22 -0.5605 -0.9152 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P01 compound treatment 0.243 0.0181 0.26 0.245 0.0168 0.28 0.3822 0.9991 3178254 Maybridge4_003147 COc1ccc(/C=C(\C#N)/c2ccc(OC)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P02 compound treatment 0.229 0.00409 0.06 0.252 0.0238 0.4 0.3236 0.8023 1202102 Maybridge4_003148 COc1ccc(cc1OC)C2SC(=S)NC(=C2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P03 compound treatment 0.243 0.0181 0.26 0.24 0.0118 0.2 0.3228 0.9912 3178255 Maybridge4_003149 O=C(NC(=S)N1CCCCC1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P04 compound treatment 0.047 -0.178 -2.54 0.046 -0.182 -3.06 -3.962 -0.9958 3178256 Maybridge4_003150 Cc1cc(Sc2ccc(Cl)cc2)nc(n1)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P05 compound treatment 0.247 0.0221 0.32 0.24 0.0118 0.2 0.3633 0.9745 3064323 Maybridge4_003151 CCOC(=O)NC(=S)Nc1ccc(F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P06 compound treatment 0.257 0.0321 0.46 0.254 0.0258 0.43 0.6306 0.9996 1496124 Maybridge4_003152 Nc1nc(Cc2ccc(F)cc2F)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P07 compound treatment 0.249 0.0241 0.34 0.238 0.00978 0.16 0.3598 0.9425 1646965 Maybridge4_003153 Oc1cc(O)n(Cc2ccco2)c(=S)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P08 compound treatment 0.207 -0.0179 -0.26 0.207 -0.0212 -0.36 -0.4329 -0.9869 3178257 Maybridge4_003154 COc1cc(NC(=O)C(Sc2nc(C)cc(C)c2C#N)c3ccccc3)c(OC)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P09 compound treatment 0.261 0.0361 0.52 0.222 -0.00622 -0.1 0.2913 0.553 1555108 Maybridge4_003155 Sc1nc2ccccc2c(=O)n1CCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P10 compound treatment 0.229 0.00409 0.06 0.232 0.00378 0.06 0.0863 0.9992 1688911 Maybridge4_003156 CN(C(=O)N(C)C(=O)c1ccccc1)C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P11 compound treatment 0.098 -0.127 -1.82 0.102 -0.126 -2.12 -2.7815 -0.997 1186033 Maybridge4_003157 CCNC(=S)Nc1ccc(NC(=O)c2ccccc2O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P12 compound treatment 0.216 -0.00891 -0.13 0.219 -0.00922 -0.15 -0.1995 -0.9953 3064360 Maybridge4_003158 CN(C)/C=N/c1nonc1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P13 compound treatment 0.279 0.0541 0.77 0.206 -0.0222 -0.37 0.2834 0.33 3178258 Maybridge4_003159 COc1ccccc1/C=C(\C#N)/c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P14 compound treatment 0.229 0.00409 0.06 0.233 0.00478 0.08 0.0981 0.988 1641024 Maybridge4_003160 CC(C)NC(=O)Oc1noc2ccc(Cl)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P15 compound treatment 0.253 0.0281 0.4 0.233 0.00478 0.08 0.3409 0.8319 3178259 Maybridge4_003161 CS/C(=N\c1c(C)cccc1C)/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P16 compound treatment 0.218 -0.00691 -0.1 0.256 0.0278 0.47 0.2599 0.5452 1687023 Maybridge4_003162 CC(C)(C)C(=O)Nc1cccc(c1)c2cc(no2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P17 compound treatment 0.226 0.00109 0.02 0.218 -0.0102 -0.17 -0.1102 -0.64 3064362 Maybridge4_003163 Cc1nc(S)nc(O)c1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P18 compound treatment 0.253 0.0281 0.4 0.232 0.00378 0.06 0.329 0.8088 1159384 Maybridge4_003164 COC(=O)c1c(NC(=O)NCc2ccccc2)onc1c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P19 compound treatment 0.29 0.0651 0.93 0.252 0.0238 0.4 0.9406 0.9285 1135236 Maybridge4_003165 Clc1ccc(cc1)C(=O)Oc2ccccc2OCC(=O)NCc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P20 compound treatment 0.061 -0.164 -2.34 0.059 -0.169 -2.84 -3.6661 -0.9955 3178260 Maybridge4_003166 CSc1nc(NC(=O)NS(=O)(=O)Cc2ccc(Cl)cc2Cl)nc(n1)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P21 compound treatment 0.275 0.0501 0.72 0.295 0.0668 1.12 1.2992 0.9766 1287410 Maybridge4_003167 CSc1nc2ccccc2c(=O)n1c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P22 compound treatment 0.266 0.0411 0.59 0.274 0.0458 0.77 0.959 0.9912 3178261 Maybridge4_003168 COC(=O)c1ccc(nc1)C(=O)Nc2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P23 mock treatment 0.219 -0.00591 -0.08 0.239 0.0108 0.18 0.0682 0.3416 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2057 P24 mock treatment 0.21 -0.0149 -0.21 0.201 -0.0272 -0.46 -0.4738 -0.9398 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A01 compound treatment 0.253 0.0191 0.27 0.279 0.051 0.86 0.7991 0.8887 3064365 Maybridge4_003169 Clc1ccccc1CN2C(=O)CNC2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A02 compound treatment 0.342 0.108 1.55 0.332 0.104 1.75 2.3283 0.9982 3178262 Maybridge4_003170 Cc1cc(SCC(=O)NN)c(C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A03 compound treatment 0.349 0.115 1.65 0.324 0.096 1.61 2.3041 0.9999 1123055 Maybridge4_003171 Clc1ccccc1OCCN2C(=O)CNC2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A04 compound treatment 0.328 0.0941 1.35 0.252 0.024 0.4 1.2372 0.8803 3178263 Maybridge4_003172 CC(=O)N1c2ccccc2C=Cc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A05 compound treatment 0.232 -0.00187 -0.03 0.229 0.00103 0.02 -0.0067 -0.2107 3178264 Maybridge4_003173 COc1nc(NC(=O)NS(=O)(=O)Nc2cccc3cccnc23)nc(OC)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A06 compound treatment 0.268 0.0341 0.49 0.179 -0.049 -0.82 -0.236 -0.2469 1697760 Maybridge4_003174 S=C(NC1CC2CC1C=C2)Nc3ccc4[nH]ccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A07 compound treatment 0.245 0.0111 0.16 0.26 0.032 0.54 0.4927 0.8787 3064405 Maybridge4_003175 CNc1nc2c(Cl)cc(Cl)cc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A08 compound treatment 0.226 -0.00787 -0.11 0.112 -0.116 -1.95 -1.456 -0.7468 3064407 Maybridge4_003176 CC(C)OC(=S)Nc1cccc(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A09 compound treatment 0.226 -0.00787 -0.11 0.24 0.012 0.2 0.0631 0.2731 3178265 Maybridge4_003177 CCN(C(=O)c1cnccc1C(F)(F)F)c2c(C)cccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A10 compound treatment 0.241 0.00712 0.1 0.195 -0.033 -0.55 -0.3192 -0.5673 1316937 Maybridge4_003178 Cc1ccc(C)c(COc2ccc(C)nc2NC(=S)NCc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A11 compound treatment 0.24 0.00612 0.09 0.218 -0.00997 -0.17 -0.0564 -0.2984 3064408 Maybridge4_003179 CC1(C)ONC(=O)N(C1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A12 compound treatment 0.212 -0.0219 -0.31 0.203 -0.025 -0.42 -0.5176 -0.9896 1490878 Maybridge4_003180 COc1ccccc1C2CCN(CC2)C(=O)c3cccnc3Sc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A13 compound treatment 0.231 -0.00287 -0.04 0.246 0.018 0.3 0.1849 0.6055 3064412 Maybridge4_003181 FC(F)(F)c1cccc(c1)n2c(noc2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A14 compound treatment 0.115 -0.119 -1.7 0.139 -0.089 -1.49 -2.2582 -0.9979 1158023 Maybridge4_003182 Sc1nnc(CSCc2cccc3ccccc23)n1C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A15 compound treatment 0.162 -0.0719 -1.03 0.122 -0.106 -1.78 -1.9846 -0.9661 3064413 Maybridge4_003183 Brc1ccc(cc1)C(=O)CSc2nc(c3cccs3)c(C#N)c(=O)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A16 compound treatment 0.197 -0.0369 -0.53 0.23 0.00203 0.03 -0.3489 -0.66 1059941 Maybridge4_003184 OC(=O)c1cc2cc(Cl)ccc2oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A17 compound treatment 0.231 -0.00287 -0.04 0.218 -0.00997 -0.17 -0.1474 -0.8554 3178266 Maybridge4_003185 Cc1cc(C)cc(Sc2ccc3nnc(c4ccccc4)n3n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A18 compound treatment 0.219 -0.0149 -0.21 0.237 0.00903 0.15 -0.0433 -0.1656 3178267 Maybridge4_003186 CC(C)c1ccc(/C=C/2\CSc3ccccc3C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A19 compound treatment 0.238 0.00412 0.06 0.238 0.01 0.17 0.1608 0.9012 3064415 Maybridge4_003187 Cc1cc(Cc2ccc(Cl)cc2)c(=O)[nH]n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A20 compound treatment 0.227 -0.00687 -0.1 0.233 0.00503 0.08 -0.0098 -0.0758 3178268 Maybridge4_003188 O=C(/C=C\1/Nc2ccccc2OC1=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A21 compound treatment 0.229 -0.00487 -0.07 0.228 3.13E-5 0.0 -0.0489 -0.7018 3064418 Maybridge4_003189 CCOC(=O)CSc1nc2cccnc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A22 compound treatment 0.258 0.0241 0.35 0.221 -0.00697 -0.12 0.1613 0.4427 3178269 Maybridge4_003190 COc1ccc(cc1)C2=Nc3ccccc3SC(C2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A23 mock treatment 0.226 -0.00787 -0.11 0.2 -0.028 -0.47 -0.4116 -0.8526 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 A24 mock treatment 0.231 -0.00287 -0.04 0.203 -0.025 -0.42 -0.3254 -0.7728 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B01 compound treatment 0.233 -8.75E-4 -0.01 0.264 0.036 0.6 0.4188 0.6923 1225177 Maybridge4_003191 CCOC(=O)c1c(C)c(=O)oc2n(nc(O)c12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B02 compound treatment 0.241 0.00712 0.1 0.231 0.00303 0.05 0.108 0.9485 1739696 Maybridge4_003192 O=C1N(Cc2ccccc2)S(=O)(=O)c3ccccc3S(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B03 compound treatment 0.26 0.0261 0.37 0.251 0.023 0.39 0.5376 0.9999 3064449 Maybridge4_003193 CC(=O)OC[C@H]1O[C@@H](NC(=O)N)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B04 compound treatment 0.298 0.0641 0.92 0.277 0.049 0.82 1.2305 0.9985 2101805 Maybridge4_003194 CCC(=O)NC(Nc1ccc(O)cc1)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B05 compound treatment 0.255 0.0211 0.3 0.268 0.04 0.67 0.6888 0.9349 1443369 Maybridge4_003195 CCc1ccc2oc3nc(N)c(C#N)cc3c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B06 compound treatment 0.266 0.0321 0.46 0.274 0.046 0.77 0.8712 0.9692 1585673 Maybridge4_003196 CCOC(=O)CCc1ccc(OCc2ccccc2)c(I)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B07 compound treatment 0.233 -8.75E-4 -0.01 0.257 0.029 0.49 0.3357 0.6887 3064452 Maybridge4_003197 CC(=O)OC[C@H]1OC[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@H]1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B08 compound treatment 0.284 0.0501 0.72 0.26 0.032 0.54 0.8871 0.9899 3178366 Maybridge4_003198 CC1(C)c2ccccc2N3CC(=O)NC31/C=C/c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B09 compound treatment 0.3 0.0661 0.95 0.271 0.043 0.72 1.1795 0.9911 1005564 Maybridge4_003199 CC(=O)Nc1ccc(cc1)c2ccc(NC(=O)C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B10 compound treatment 0.256 0.0221 0.32 0.215 -0.013 -0.22 0.0699 0.1819 3178367 Maybridge4_003200 Cc1nn(c(O)c1Cc2c(Cl)cccc2Cl)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B11 compound treatment 0.267 0.0331 0.47 0.265 0.037 0.62 0.7745 0.991 1167085 Maybridge4_003201 COc1ccc(CC2CCc3ncc(C)cc3C2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B12 compound treatment 0.246 0.0121 0.17 0.224 -0.00397 -0.07 0.0755 0.4066 3178368 Maybridge4_003202 N/N=C(/Cn1nnc(n1)N2CCCCC2)\c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B13 compound treatment 0.23 -0.00387 -0.06 0.228 3.13E-5 0.0 -0.0388 -0.7004 3064453 Maybridge4_003203 S=c1sc2ccccc2n1CCn3c(=S)sc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B14 compound treatment 0.267 0.0331 0.47 0.243 0.015 0.25 0.5134 0.9565 1238987 Maybridge4_003204 CCCc1c(C)nc(SCC(=O)C(C)(C)C)nc1OC(=O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B15 compound treatment 0.237 0.00312 0.04 0.24 0.012 0.2 0.1744 0.8432 3178369 Maybridge4_003205 CC1CN=C(S1)N(CCc2ccccc2)C(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B16 compound treatment 0.239 0.00512 0.07 0.259 0.031 0.52 0.4201 0.7988 1004236 Maybridge4_003206 Cc1ccccc1NC(=N)NC(=N)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B17 compound treatment 0.235 0.00112 0.02 0.241 0.013 0.22 0.166 0.7571 1381247 Maybridge4_003207 Sc1nnc(CCCc2nnc(S)o2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B18 compound treatment 0.236 0.00212 0.03 0.222 -0.00597 -0.1 -0.0493 -0.4713 1184925 Maybridge4_003208 CN(C)C(=O)Oc1nc(SCC(=O)c2ccc(Cl)cc2)nc(C)c1CC(=C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B19 compound treatment 0.276 0.0421 0.6 0.229 0.00103 0.02 0.4383 0.7271 3064457 Maybridge4_003209 COc1ccccc1C2CCN(CCCOc3ccc(Cl)cc3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B20 compound treatment 0.233 -8.75E-4 -0.01 0.237 0.00903 0.15 0.0983 0.6465 3178370 Maybridge4_003210 CCNC(=S)NCC1CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B21 compound treatment 0.236 0.00212 0.03 0.251 0.023 0.39 0.2948 0.7604 1489027 Maybridge4_003211 Oc1c(Cl)c(=O)n(Cc2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B22 compound treatment 0.261 0.0271 0.39 0.252 0.024 0.4 0.5596 0.9998 1250091 Maybridge4_003212 O=C(Nc1ccc(cc1)S(=O)(=O)NC2(CC3CC4CC(C3)C2)C4)C5CC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B23 mock treatment 0.256 0.0221 0.32 0.231 0.00303 0.05 0.2598 0.8104 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 B24 mock treatment 0.282 0.0481 0.69 0.23 0.00203 0.03 0.5109 0.7412 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C01 compound treatment 0.303 0.0691 0.99 0.209 -0.019 -0.32 0.474 0.4563 3064501 Maybridge4_003213 O=C(Nc1ccccc1)Nc2ccc3nnsc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C02 compound treatment 0.24 0.00612 0.09 0.216 -0.012 -0.2 -0.0801 -0.3655 1507422 Maybridge4_003214 CC(C)(C)c1ccc(OCC(=O)n2ncc(C#N)c2N)c(c1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C03 compound treatment 0.324 0.0901 1.29 0.277 0.049 0.82 1.4935 0.9765 1402640 Maybridge4_003215 COc1ccc(OCCN2C(=O)CNC2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C04 compound treatment 0.183 -0.0509 -0.73 0.095 -0.133 -2.23 -2.0926 -0.8915 1499674 Maybridge4_003216 Cc1ccc2N(CCCc2c1)C(=O)CC(=O)N3CCCc4cc(C)ccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C05 compound treatment 0.201 -0.0329 -0.47 0.152 -0.076 -1.28 -1.2341 -0.9081 3064504 Maybridge4_003217 CC(C)c1ccc(NC(=S)Sc2ccc(F)cc2F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C06 compound treatment 0.293 0.0591 0.85 0.262 0.034 0.57 1.0019 0.9817 1213648 Maybridge4_003218 Cc1ccc(CC(=S)N2CCOCC2)cn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C07 compound treatment 0.165 -0.0689 -0.99 0.133 -0.095 -1.59 -1.8237 -0.9733 3178371 Maybridge4_003219 CCN(C(=O)c1cnccc1C(F)(F)F)c2nc3cc(Cl)ccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C08 compound treatment 0.276 0.0421 0.6 0.257 0.029 0.49 0.7706 0.9945 1153252 Maybridge4_003220 COc1cc2cc(OCc3c(F)cccc3Cl)nc(C)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C09 compound treatment 0.284 0.0501 0.72 0.274 0.046 0.77 1.0533 0.9993 3178372 Maybridge4_003221 CSc1cc(c(cn1)C(=O)Nc2c(C)cccc2C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C10 compound treatment 0.216 -0.0179 -0.26 0.211 -0.017 -0.28 -0.3822 -0.9986 3064507 Maybridge4_003222 CCC/N=c/1\ssc(=O)n1CCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C11 compound treatment 0.241 0.00712 0.1 0.235 0.00703 0.12 0.1555 0.9973 3178373 Maybridge4_003223 COc1nccc(c1C(=O)NC(=O)Nc2c(C)cccc2C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C12 compound treatment 0.283 0.0491 0.7 0.274 0.046 0.77 1.0432 0.9989 3064509 Maybridge4_003224 FC(F)(F)c1ccc(NC(=O)CSCc2cccc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C13 compound treatment 0.241 0.00712 0.1 0.261 0.033 0.55 0.4641 0.8233 1304317 Maybridge4_003225 Clc1cccc(c1)c2noc(=O)n2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C14 compound treatment 0.298 0.0641 0.92 0.257 0.029 0.49 0.9931 0.9562 1154699 Maybridge4_003226 CC(C)COC(=O)c1cn(C2CCCCC2)c3ccccc3c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C15 compound treatment 0.298 0.0641 0.92 0.256 0.028 0.47 0.9813 0.9519 1407275 Maybridge4_003227 COC(=O)C1c2ccccc2Oc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C16 compound treatment 0.273 0.0391 0.56 0.276 0.048 0.81 0.9658 0.9841 1661086 Maybridge4_003228 COc1ccc(CC2C(=O)OC(C)(C)OC2=O)c(Cl)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C17 compound treatment 0.237 0.00312 0.04 0.22 -0.00797 -0.13 -0.063 -0.4465 3178374 Maybridge4_003229 CC1=C(Sc2ccccc2N1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C18 compound treatment 0.258 0.0241 0.35 0.233 0.00503 0.08 0.3037 0.8549 3064548 Maybridge4_003230 O=C1/C(=C/c2c[nH]c3ccccc23)/CSc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C19 compound treatment 0.202 -0.0319 -0.46 0.248 0.02 0.34 -0.0847 -0.1494 3178375 Maybridge4_003231 Cc1cc(Cc2cccs2)c(=O)[nH]n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C20 compound treatment 0.072 -0.162 -2.32 0.053 -0.175 -2.94 -3.7138 -0.9931 1550561 Maybridge4_003232 OC(COc1ccc(F)cc1)(c2ccc(Cl)cc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C21 compound treatment 0.253 0.0191 0.27 0.248 0.02 0.34 0.4312 0.9948 1029711 Maybridge4_003233 CCOC(=O)c1cc(=O)c2ccc(OCc3ccccc3)cc2o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C22 compound treatment 0.046 -0.188 -2.69 0.042 -0.186 -3.12 -4.1073 -0.9972 3178376 Maybridge4_003234 Oc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4ccccc4O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C23 mock treatment 0.23 -0.00387 -0.06 0.194 -0.034 -0.57 -0.4423 -0.7722 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 C24 mock treatment 0.226 -0.00787 -0.11 0.197 -0.031 -0.52 -0.4472 -0.8408 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D01 compound treatment 0.29 0.0561 0.8 0.238 0.01 0.17 0.6867 0.8372 1653141 Maybridge4_003235 Nc1cc(=O)[nH]c(=O)n1c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D02 compound treatment 0.258 0.0241 0.35 0.228 3.13E-5 0.0 0.2444 0.7082 3178377 Maybridge4_003236 CNS(=O)(=O)c1ccc(cc1S(=O)c2ccccc2C(=O)O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D03 compound treatment 0.249 0.0151 0.22 0.225 -0.00297 -0.05 0.1177 0.5304 1915933 Maybridge4_003237 COC(=O)Nc1nc2cc(ccc2[nH]1)c3n[nH]c(=O)c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D04 compound treatment 0.35 0.116 1.66 0.296 0.068 1.14 1.9819 0.9833 1252966 Maybridge4_003238 Oc1c(c2ccccc2)c(=O)[nH]c3ccc(F)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D05 compound treatment 0.31 0.0761 1.09 0.314 0.086 1.44 1.791 0.9903 3178378 Maybridge4_003239 Brc1ccc(cc1)C(=O)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D06 compound treatment 0.255 0.0211 0.3 0.267 0.039 0.66 0.6769 0.9383 3064551 Maybridge4_003240 CCN1C(=O)N(CC)C(=O)C(=Cc2c(O)n(CC)c(=O)n(CC)c2=O)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D07 compound treatment 0.242 0.00812 0.12 0.303 0.075 1.26 0.9727 0.7691 3178379 Maybridge4_003241 CC(=O)O[C@@H]1CO[C@@H]([C@@H](OC(=O)C)[C@@H]1OC(=O)C)c2nc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D08 compound treatment 0.287 0.0531 0.76 0.297 0.069 1.16 1.3566 0.9791 3178380 Maybridge4_003242 CC1(C)c2ccccc2N3CC(=O)NC31/C=C/c4ccc(cc4)N5CCOCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D09 compound treatment 0.271 0.0371 0.53 0.291 0.063 1.06 1.1236 0.9492 1190502 Maybridge4_003243 Clc1ccc2n(CN3CCCCC3)c4ccc(Cl)cc4c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D10 compound treatment 0.109 -0.125 -1.79 0.078 -0.15 -2.52 -3.0429 -0.9859 3064581 Maybridge4_003244 CNC(=S)Nc1cc(Cl)cc(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D11 compound treatment 0.268 0.0341 0.49 0.228 3.13E-5 0.0 0.3455 0.7079 1208488 Maybridge4_003245 OC(=O)CCC1CCCCCCCCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D12 compound treatment 0.287 0.0531 0.76 0.262 0.034 0.57 0.9412 0.9901 3064582 Maybridge4_003246 O/N=C(/Cn1nnc(n1)N2CCCC2)\c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D13 compound treatment 0.249 0.0151 0.22 0.302 0.074 1.24 1.0316 0.8179 3064584 Maybridge4_003247 C([n+]1ccccc1)[n+]2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D14 compound treatment 0.233 -8.75E-4 -0.01 0.258 0.03 0.5 0.3476 0.6893 3178381 Maybridge4_003248 Cc1nc(SCC(=O)C(C)(C)C)nc(O)c1Cc2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D15 compound treatment 0.31 0.0761 1.09 0.235 0.00703 0.12 0.8534 0.7792 3178382 Maybridge4_003249 CC(N(C(=O)Nc1ccc(Cl)cc1)C2=NCC(C)S2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D16 compound treatment 0.332 0.0981 1.4 0.235 0.00703 0.12 1.0759 0.7639 3064586 Maybridge4_003250 CC(C)(C)c1cs/c(=N\c2ccc(F)cc2F)/o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D17 compound treatment 0.294 0.0601 0.86 0.296 0.068 1.14 1.4155 0.9902 3178383 Maybridge4_003251 C(CCc1nnc(SCc2ccccc2)o1)Cc3nnc(SCc4ccccc4)o3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D18 compound treatment 0.349 0.115 1.65 0.266 0.038 0.64 1.6158 0.9149 3064589 Maybridge4_003252 FC(F)(F)c1ccc(Cl)c(Nc2ncnc(n2)n3cccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D19 compound treatment 0.276 0.0421 0.6 0.283 0.055 0.92 1.0792 0.9786 1521138 Maybridge4_003253 COc1ccc(CCNC(=O)C2CCCCC2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D20 compound treatment 0.288 0.0541 0.77 0.257 0.029 0.49 0.892 0.9751 2078178 Maybridge4_003254 CC(C)[n+]1c(C)csc1Nc2ccc(F)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D21 compound treatment 0.273 0.0391 0.56 0.271 0.043 0.72 0.9064 0.9921 1308049 Maybridge4_003255 O=c1cc(NCc2ccccc2)[nH]nc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D22 compound treatment 0.169 -0.0649 -0.93 0.138 -0.09 -1.51 -1.7239 -0.9727 3178478 Maybridge4_003256 CCCC1=NNC(=O)C1Cc2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D23 mock treatment 0.271 0.0371 0.53 0.226 -0.00197 -0.03 0.3521 0.6618 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 D24 mock treatment 0.258 0.0241 0.35 0.182 -0.046 -0.77 -0.3016 -0.3568 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E01 compound treatment 0.253 0.0191 0.27 0.22 -0.00797 -0.13 0.0989 0.3247 3064592 Maybridge4_003257 CSC1=NCC(=O)N1Cc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E02 compound treatment 0.267 0.0331 0.47 0.24 0.012 0.2 0.4778 0.9277 1522772 Maybridge4_003258 CCCCc1cc(C)c2ncc(C(=O)O)c(O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E03 compound treatment 0.249 0.0151 0.22 0.207 -0.021 -0.35 -0.0959 -0.2321 1340715 Maybridge4_003259 CC(C)NC(=O)N(Cc1cccs1)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E04 compound treatment 0.245 0.0111 0.16 0.089 -0.139 -2.33 -1.5368 -0.6573 1280280 Maybridge4_003260 Oc1c(c2ccccc2)c(=O)n3c4ccccc4c5cccc1c53 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E05 compound treatment 0.312 0.0781 1.12 0.244 0.016 0.27 0.9804 0.853 3178479 Maybridge4_003261 COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc2nc(C)c3CS(=O)(=O)CCc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E06 compound treatment 0.32 0.0861 1.23 0.269 0.041 0.69 1.3581 0.9622 1428973 Maybridge4_003262 COC(=O)C1=C(C)NC(=O)CC1c2ccccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E07 compound treatment 0.27 0.0361 0.52 0.28 0.052 0.87 0.9829 0.9686 3178480 Maybridge4_003263 CSc1nc(nc(N)c1C#N)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E08 compound treatment 0.297 0.0631 0.9 0.296 0.068 1.14 1.4459 0.9932 1476870 Maybridge4_003264 COc1ccc2n(C3CC3)c(C)c(C(=O)ON4C(=O)CCC4=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E09 compound treatment 0.32 0.0861 1.23 0.299 0.071 1.19 1.7141 0.9999 3178481 Maybridge4_003265 Cc1cccc(C)c1NC(=O)c2cnc(NC3CCCCC3)cc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E10 compound treatment 0.314 0.0801 1.15 0.254 0.026 0.44 1.1193 0.9126 3063905 Maybridge4_003266 FC(F)(F)c1cc(Cl)c2ncc(nc2c1)c3ccc(Br)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E11 compound treatment 0.126 -0.108 -1.54 0.084 -0.144 -2.42 -2.7997 -0.9765 3178482 Maybridge4_003267 FC(F)(F)c1ccc(nc1)S(=O)(=O)/C(=C/c2ccsc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E12 compound treatment 0.307 0.0731 1.05 0.272 0.044 0.74 1.2622 0.9855 1329285 Maybridge4_003268 CC(C)C1CCC(C)CC1NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E13 compound treatment 0.279 0.0451 0.65 0.276 0.048 0.81 1.0264 0.9939 3063910 Maybridge4_003269 COc1ccccc1c2nn(c3cccc(n3)C(F)(F)F)c(=O)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E14 compound treatment 0.276 0.0421 0.6 0.305 0.077 1.29 1.3403 0.9396 1482860 Maybridge4_003270 COc1ccc(Oc2ncccc2NC(=O)c3ccc(OC)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E15 compound treatment 0.305 0.0711 1.02 0.261 0.033 0.55 1.1114 0.9593 1317058 Maybridge4_003271 COc1ccc(CNc2nc(c3cccs3)c(C#N)c(=O)n2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E16 compound treatment 0.221 -0.0129 -0.18 0.23 0.00203 0.03 -0.1061 -0.5666 3063941 Maybridge4_003272 Cc1n[nH]c(=S)n1/N=C\c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E17 compound treatment 0.286 0.0521 0.75 0.236 0.00803 0.13 0.6225 0.8216 1597311 Maybridge4_003273 CCOC(CNc1ccc2nnc(c3ccccc3)n2n1)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E18 compound treatment 0.24 0.00612 0.09 0.175 -0.053 -0.89 -0.5667 -0.6344 3063945 Maybridge4_003274 O=C1/C(=C\c2c[nH]c3ccccc23)/C(Oc4ccccc14)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E19 compound treatment 0.234 1.25E-4 0.0 0.268 0.04 0.67 0.4764 0.709 3178483 Maybridge4_003275 Cc1cc(Cc2ccc(cc2)C(F)(F)F)c(=O)[nH]n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E20 compound treatment 0.262 0.0281 0.4 0.322 0.094 1.58 1.4004 0.8599 1460994 Maybridge4_003276 CN(C)CCC(O)(CCc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E21 compound treatment 0.24 0.00612 0.09 0.269 0.041 0.69 0.5489 0.7907 3063949 Maybridge4_003277 CN(C)/C=N/c1nnc(Sc2ccnc3cc(Cl)ccc23)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E22 compound treatment 0.271 0.0371 0.53 0.251 0.023 0.39 0.6488 0.9878 1708827 Maybridge4_003278 CCOC(=O)COc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E23 mock treatment 0.245 0.0111 0.16 0.25 0.022 0.37 0.374 0.929 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 E24 mock treatment 0.212 -0.0219 -0.31 0.215 -0.013 -0.22 -0.3752 -0.9843 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F01 compound treatment 0.247 0.0131 0.19 0.209 -0.019 -0.32 -0.0924 -0.2499 3063951 Maybridge4_003279 Brc1ccc(cc1)C(=O)C2C(=O)OC(=CC2=O)c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F02 compound treatment 0.233 -8.75E-4 -0.01 0.288 0.06 1.01 0.7036 0.6983 1535413 Maybridge4_003280 CN1CCN(CCN2C(=O)c3ccccc3Sc4cc(Cl)ccc4S2(=O)=O)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F03 compound treatment 0.23 -0.00387 -0.06 0.221 -0.00697 -0.12 -0.1219 -0.9418 1134402 Maybridge4_003281 O=S(=O)(N(CCC#N)C1CCCCC1)c2cccc3nsnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F04 compound treatment 0.272 0.0381 0.55 0.132 -0.096 -1.61 -0.7534 -0.443 3178484 Maybridge4_003282 Cc1ccccc1/C=C/c2c[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F05 compound treatment 0.243 0.00912 0.13 0.291 0.063 1.06 0.8404 0.7884 3063955 Maybridge4_003283 OC(=O)c1ccc(cc1C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F06 compound treatment 0.297 0.0631 0.9 0.291 0.063 1.06 1.3865 0.9969 1062519 Maybridge4_003284 O=C(C1CCCCC1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F07 compound treatment 0.355 0.121 1.73 0.326 0.098 1.65 2.3885 0.9997 3178485 Maybridge4_003285 O=C(OC[C@H]1O[C@@H](C#N)[C@H](OC(=O)c2ccccc2)[C@@H]1OC(=O)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F08 compound treatment 0.094 -0.14 -2.0 0.089 -0.139 -2.33 -3.064 -0.9971 1658235 Maybridge4_003286 CC1(C)c2ccccc2N(CCC(=O)N)C31Oc4ccc5ccccc5c4C=C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F09 compound treatment 0.05 -0.184 -2.63 0.076 -0.152 -2.55 -3.6633 -0.9999 1416171 Maybridge4_003287 OC(CN1CCNCC1)Cn2c3ccc(Br)cc3c4cc(Br)ccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F10 compound treatment 0.311 0.0771 1.1 0.308 0.08 1.34 1.7299 0.9952 1438412 Maybridge4_003288 O=C(Cn1nnc(n1)N2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F11 compound treatment 0.282 0.0481 0.69 0.323 0.095 1.6 1.6146 0.9294 3178486 Maybridge4_003289 COc1cc(COC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)O)cc(OC)c1.C1CCC(CC1)NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F12 compound treatment 0.248 0.0141 0.2 0.318 0.09 1.51 1.2114 0.7946 1614817 Maybridge4_003290 COc1ccc(CCNC(=S)NC2CC2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F13 compound treatment 0.262 0.0281 0.4 0.289 0.061 1.02 1.0088 0.9167 3178487 Maybridge4_003291 CCN1/C(=C\C(=S)Nc2ccccc2)/Sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F14 compound treatment 0.34 0.106 1.52 0.289 0.061 1.02 1.7977 0.9817 1593331 Maybridge4_003292 CC(C)(C)C(=O)Cn1nnc(n1)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F15 compound treatment 0.327 0.0931 1.33 0.334 0.106 1.78 2.2003 0.9898 3063998 Maybridge4_003293 CC1=[N+](C)c2cc(ccc2C1(C)C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F16 compound treatment 0.27 0.0361 0.52 0.261 0.033 0.55 0.7574 0.9994 3178488 Maybridge4_003294 Fc1ccc(NC(=S)Nc2cc(ccc2N3CCCC3)C(F)(F)F)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F17 compound treatment 0.334 0.1 1.43 0.319 0.091 1.53 2.0931 0.9995 1142281 Maybridge4_003295 CN1C(=C(C(NC1=O)c2ccccc2)C(=O)OCc3ccccc3)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F18 compound treatment 0.288 0.0541 0.77 0.231 0.00303 0.05 0.5834 0.752 1704243 Maybridge4_003296 COCc1cc(O)n2nc(Nc3cc(Cl)ccc3C)nc2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F19 compound treatment 0.314 0.0801 1.15 0.242 0.014 0.24 0.9769 0.835 1313602 Maybridge4_003297 O=c1cc(NCc2ccccc2)n(c3ccccc3)c(=O)n1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F20 compound treatment 0.285 0.0511 0.73 0.267 0.039 0.66 0.9803 0.9985 1473392 Maybridge4_003298 CCN(CC)C(=O)Sc1nc2ccccc2c(=O)n1CC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F21 compound treatment 0.302 0.0681 0.97 0.252 0.024 0.4 0.9742 0.9238 1547311 Maybridge4_003299 OC(=O)C1(C2C3C14)C5C2CCC3C45C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F22 compound treatment 0.263 0.0291 0.42 0.27 0.042 0.71 0.7934 0.9684 3064002 Maybridge4_003300 CCCc1cc(=O)oc2cc(OC(=O)/C=C/c3cccs3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F23 mock treatment 0.262 0.0281 0.4 0.24 0.012 0.2 0.4273 0.9492 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 F24 mock treatment 0.258 0.0241 0.35 0.218 -0.00997 -0.17 0.1257 0.3278 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G01 compound treatment 0.28 0.0461 0.66 0.213 -0.015 -0.25 0.2889 0.4092 1507436 Maybridge4_003301 Cc1cc(no1)N(Cc2cccc(Cl)c2Cl)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G02 compound treatment 0.291 0.0571 0.82 0.226 -0.00197 -0.03 0.5544 0.678 1593004 Maybridge4_003302 O=c1ccc(n[nH]1)c2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G03 compound treatment 0.299 0.0651 0.93 0.313 0.085 1.43 1.6678 0.9786 3178489 Maybridge4_003303 CSC1=N/C(=C\c2ccccc2Cl)/C(=O)N1N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G04 compound treatment 0.257 0.0231 0.33 0.294 0.066 1.11 1.0176 0.8798 3178490 Maybridge4_003304 COc1ccc(C/N=C(\C)/c2c(O)c3ccccc3n(C)c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G05 compound treatment 0.292 0.0581 0.83 0.263 0.035 0.59 1.0036 0.9856 3064042 Maybridge4_003305 CCN(C(=O)c1cnccc1C(F)(F)F)c2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G06 compound treatment 0.275 0.0411 0.59 0.309 0.081 1.36 1.3776 0.9297 1261792 Maybridge4_003306 Cc1ccc(Oc2ncccc2NC(=O)C(=S)NCc3ccccc3)c4CCCc41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G07 compound treatment 0.343 0.109 1.56 0.322 0.094 1.58 2.2197 1.0 3064045 Maybridge4_003307 Cc1nc(c2nnc(o2)c3ccccc3)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G08 compound treatment 0.32 0.0861 1.23 0.303 0.075 1.26 1.7616 0.9999 3178491 Maybridge4_003308 COc1ccc(cc1OC2CCCC2)C3CC(=O)NN3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G09 compound treatment 0.336 0.102 1.46 0.258 0.03 0.5 1.3893 0.8991 3064046 Maybridge4_003309 CNC(=O)NC(=O)c1cnccc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G10 compound treatment 0.318 0.0841 1.2 0.334 0.106 1.78 2.1092 0.9818 1193128 Maybridge4_003310 Cc1c(OCc2ccc(Cl)cc2Cl)ccc3C(=O)CC(C)(C)Oc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G11 compound treatment 0.224 -0.00987 -0.14 0.248 0.02 0.34 0.1379 0.378 3064048 Maybridge4_003311 COC(=O)c1cnc(Oc2c(Cl)cc(N)cc2Cl)cc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G12 compound treatment 0.307 0.0731 1.05 0.309 0.081 1.36 1.7013 0.9916 1126959 Maybridge4_003312 COc1ccccc1C2CCN(CC2)C(=O)CSCc3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G13 compound treatment 0.246 0.0121 0.17 0.279 0.051 0.86 0.7283 0.8334 3064052 Maybridge4_003313 COc1cccc(OC)c1CN(C)C(=O)c2cnc(Oc3ccccc3)cc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G14 compound treatment 0.3 0.0661 0.95 0.324 0.096 1.61 1.8085 0.9677 1245694 Maybridge4_003314 NNC(=O)Cn1c2ccccc2c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G15 compound treatment 0.315 0.0811 1.16 0.247 0.019 0.32 1.0464 0.8694 3064053 Maybridge4_003315 CC1CC(=O)NN=C1c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G16 compound treatment 0.203 -0.0309 -0.44 0.198 -0.03 -0.5 -0.6679 -0.9979 3178582 Maybridge4_003316 COc1cc(/C=N\n2cn[nH]c2=S)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G17 compound treatment 0.315 0.0811 1.16 0.283 0.055 0.92 1.4736 0.9936 1565631 Maybridge4_003317 CSc1nc2cccc(F)c2c(=O)n1c3ccc(C)c(C)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G18 compound treatment 0.306 0.0721 1.03 0.271 0.043 0.72 1.2402 0.9848 1496711 Maybridge4_003318 Cc1ccccc1NC(=O)COc2ccc3C(=O)CC(C)(C)Oc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G19 compound treatment 0.24 0.00612 0.09 0.213 -0.015 -0.25 -0.1157 -0.4348 3178583 Maybridge4_003319 CCc1nc(S)[nH]c(=O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G20 compound treatment 0.22 -0.0139 -0.2 0.229 0.00103 0.02 -0.1281 -0.643 1520911 Maybridge4_003320 O=C1CC(Sc2ccccc2N1)c3coc4ccccc4c3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G21 compound treatment 0.16 -0.0739 -1.06 0.238 0.01 0.17 -0.6281 -0.587 1387364 Maybridge4_003321 CC(=O)N1CCc2cc(NC(=S)Nc3ccccc3Cl)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G22 compound treatment 0.249 0.0151 0.22 0.218 -0.00997 -0.17 0.0347 0.1268 1175310 Maybridge4_003322 O=C(COc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccccc4)Nc5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G23 mock treatment 0.221 -0.0129 -0.18 0.227 -9.69E-4 -0.02 -0.1417 -0.7666 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 G24 mock treatment 0.235 0.00112 0.02 0.184 -0.044 -0.74 -0.5104 -0.6915 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H01 compound treatment 0.251 0.0171 0.24 0.218 -0.00997 -0.17 0.0549 0.1851 3064847 Maybridge4_003323 N=C(NC(=S)Nc1ccccc1)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H02 compound treatment 0.245 0.0111 0.16 0.286 0.058 0.97 0.8012 0.8119 1265943 Maybridge4_003324 Oc1cc(c2ccc(F)cc2)n(c3ccccc3)c(=O)c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H03 compound treatment 0.327 0.0931 1.33 0.217 -0.011 -0.18 0.8117 0.6036 1493327 Maybridge4_003325 CC(C)c1c(Br)c(=O)oc2c3CCCN4CCCc(cc12)c43 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H04 compound treatment 0.323 0.0891 1.27 0.229 0.00103 0.02 0.9137 0.7166 1020946 Maybridge4_003326 NC(=O)NCCc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H05 compound treatment 0.288 0.0541 0.77 0.309 0.081 1.36 1.5091 0.9643 3064848 Maybridge4_003327 C/C(=N/O)/CC(c1ccccc1)c2c(O)c3ccccc3oc2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H06 compound treatment 0.274 0.0401 0.57 0.269 0.041 0.69 0.8928 0.9959 1378346 Maybridge4_003328 Cn1c(=O)n(C)c2ncn(CC(O)COc3ccccc3)c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H07 compound treatment 0.341 0.107 1.53 0.316 0.088 1.48 2.1282 0.9998 3064849 Maybridge4_003329 CO[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@H](OC(=O)c3ccccc3)[C@H]1OC(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H08 compound treatment 0.369 0.135 1.93 0.313 0.085 1.43 2.3758 0.9889 1554777 Maybridge4_003330 CCn1c2C(=O)CCCc2c3cc(OCc4ccccc4)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H09 compound treatment 0.333 0.0991 1.42 0.28 0.052 0.87 1.6201 0.9729 3064850 Maybridge4_003331 OC1=C(C(=O)c2ccccc12)c3ccc(I)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H10 compound treatment 0.289 0.0551 0.79 0.295 0.067 1.13 1.3531 0.9849 3178584 Maybridge4_003332 FC(F)(F)c1cccc(c1)n2c(S)nnc2Cn3nnc(n3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H11 compound treatment 0.281 0.0471 0.67 0.328 0.1 1.68 1.6638 0.9196 1668484 Maybridge4_003333 Fc1ccc(cc1)N(C(=O)C2(CC3CC4CC(C3)C2)C4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H12 compound treatment 0.311 0.0771 1.1 0.341 0.113 1.9 2.1215 0.9667 3064851 Maybridge4_003334 COc1ccc(CCN/2C(=O)CS\C2=N/C3CC3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H13 compound treatment 0.256 0.0221 0.32 0.335 0.107 1.8 1.494 0.8191 1561039 Maybridge4_003335 O=c1[nH]c2ccccc2c(=O)n1CCSc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H14 compound treatment 0.244 0.0101 0.14 0.277 0.049 0.82 0.6843 0.819 3064852 Maybridge4_003336 CC/N=C(/Nc1ccc(cc1)C(C)(C)C)\SCC2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H15 compound treatment 0.325 0.0911 1.3 0.327 0.099 1.66 2.097 0.9928 1155855 Maybridge4_003337 Oc1c(O)c(CN2CCCCC2)c3ccccc3c1CN4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H16 compound treatment 0.305 0.0711 1.02 0.317 0.089 1.49 1.776 0.9824 3064853 Maybridge4_003338 COC(=O)c1cccc(NC(=N)NC(=N)N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H17 compound treatment 0.329 0.0951 1.36 0.304 0.076 1.28 1.8645 0.9995 3178585 Maybridge4_003339 Clc1ccc(cc1)S(=O)(=O)C2=CC34CCCC4(C2)C=C(C3)S(=O)(=O)c5ccc(Cl)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H18 compound treatment 0.299 0.0651 0.93 0.313 0.085 1.43 1.6678 0.9786 3064854 Maybridge4_003340 CC(=C)CC1C(=NNC1=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H19 compound treatment 0.262 0.0281 0.4 0.312 0.084 1.41 1.2818 0.8739 3178586 Maybridge4_003341 CC1(C)O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O1)n3cnc4c(N)ncnc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H20 compound treatment 0.195 -0.0389 -0.56 0.161 -0.067 -1.12 -1.188 -0.9473 3064855 Maybridge4_003342 Clc1ccc(NC(=S)NCC2CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H21 compound treatment 0.222 -0.0119 -0.17 0.281 0.053 0.89 0.5093 0.562 1331091 Maybridge4_003343 CN(C)CCNc1cc(nc2ccccc12)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H22 compound treatment 0.293 0.0591 0.85 0.301 0.073 1.23 1.4647 0.9836 1734961 Maybridge4_003344 CCCc1c(Cc2c(F)cccc2Cl)c(=O)oc3cc(O)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H23 mock treatment 0.237 0.00312 0.04 0.256 0.028 0.47 0.3643 0.7708 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 H24 mock treatment 0.201 -0.0329 -0.47 0.221 -0.00697 -0.12 -0.4152 -0.8569 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I01 compound treatment 0.234 1.25E-4 0.0 0.263 0.035 0.59 0.417 0.7093 3178587 Maybridge4_003345 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I02 compound treatment 0.258 0.0241 0.35 0.22 -0.00797 -0.13 0.1494 0.4038 1626253 Maybridge4_003346 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccc(Cl)c(Cl)c3)c(N)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I03 compound treatment 0.268 0.0341 0.49 0.256 0.028 0.47 0.6778 0.9998 1244996 Maybridge4_003347 CCNC(=O)N(Cc1ccccc1)Cc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I04 compound treatment 0.302 0.0681 0.97 0.284 0.056 0.94 1.354 0.9998 1073759 Maybridge4_003348 CSc1ncc(Br)c(n1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I05 compound treatment 0.33 0.0961 1.37 0.278 0.05 0.84 1.566 0.972 3178588 Maybridge4_003349 CC(C)(C)NC(=O)Nc1cnccc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I06 compound treatment 0.275 0.0411 0.59 0.272 0.044 0.74 0.9385 0.9936 3064856 Maybridge4_003350 CCOC(=O)CC1=Nn2c(nnc2SC1)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I07 compound treatment 0.344 0.11 1.58 0.298 0.07 1.18 1.945 0.9896 3178589 Maybridge4_003351 Cc1nc(C(=O)NCC(=O)c2ccc(Cl)cc2)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I08 compound treatment 0.335 0.101 1.45 0.304 0.076 1.28 1.9251 0.998 1403866 Maybridge4_003352 O=c1cc([nH]c(=O)[nH]1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I09 compound treatment 0.301 0.0671 0.96 0.309 0.081 1.36 1.6406 0.9855 3178590 Maybridge4_003353 COc1ccc(CN(C)C(=O)c2cnc(OC)cc2C(F)(F)F)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I10 compound treatment 0.197 -0.0369 -0.53 0.09 -0.138 -2.32 -2.0104 -0.8465 1529338 Maybridge4_003354 CCCCc1ccc(NC(=O)CSc2nc(C3CCCCC3)c(C#N)c(=O)[nH]2)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I11 compound treatment 0.319 0.0851 1.22 0.334 0.106 1.78 2.1194 0.9829 3064857 Maybridge4_003355 CN(C(=O)c1cn(C)c(=O)cc1C(F)(F)F)c2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I12 compound treatment 0.319 0.0851 1.22 0.321 0.093 1.56 1.9651 0.9924 1141964 Maybridge4_003356 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3cccc4nonc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I13 compound treatment 0.272 0.0381 0.55 0.289 0.061 1.02 1.1099 0.9565 3064858 Maybridge4_003357 CSc1nc(Nc2cccc(c2)C(F)(F)F)cc(c1C#N)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I14 compound treatment 0.285 0.0511 0.73 0.331 0.103 1.73 1.7399 0.9267 1260487 Maybridge4_003358 Cc1ccc(Sc2ncccc2NC(=O)c3cccc4ccccc34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I15 compound treatment 0.289 0.0551 0.79 0.27 0.042 0.71 1.0564 0.9985 1269491 Maybridge4_003359 CCOC(=O)c1cnn2c1nc(Sc3cccc(OC)c3)c4ccccc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I16 compound treatment 0.237 0.00312 0.04 0.217 -0.011 -0.18 -0.0986 -0.5203 1008109 Maybridge4_003360 S=C(Nc1ccccn1)Nc2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I17 compound treatment 0.294 0.0601 0.86 0.242 0.014 0.24 0.7746 0.8688 3064859 Maybridge4_003361 O/N=C/Nc1ccc2nnc(c3ccccc3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I18 compound treatment 0.314 0.0801 1.15 0.276 0.048 0.81 1.3804 0.9852 1290576 Maybridge4_003362 Oc1ccc2c(=O)c(coc2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I19 compound treatment 0.286 0.0521 0.75 0.285 0.057 0.96 1.2041 0.9924 3064860 Maybridge4_003363 Cc1ccc(Cc2cc(C)n[nH]c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I20 compound treatment 0.257 0.0231 0.33 0.241 0.013 0.22 0.3885 0.9798 1499068 Maybridge4_003364 CC(=O)NC1C(c2ccccc2)S(=O)(=O)c3ccccc3NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I21 compound treatment 0.193 -0.0409 -0.58 0.115 -0.113 -1.9 -1.7541 -0.8841 1721722 Maybridge4_003365 CC(=O)N1CCc2cc(NC(=S)NCc3cccs3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I22 compound treatment 0.23 -0.00387 -0.06 0.259 0.031 0.52 0.3291 0.6283 1210152 Maybridge4_003366 CCC(=O)N1C(CC(=Nc2ccccc12)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I23 mock treatment 0.249 0.0151 0.22 0.217 -0.011 -0.18 0.0228 0.0803 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 I24 mock treatment 0.191 -0.0429 -0.61 0.218 -0.00997 -0.17 -0.552 -0.8683 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J01 compound treatment 0.251 0.0171 0.24 0.222 -0.00597 -0.1 0.1024 0.3868 1243119 Maybridge4_003367 Cc1c(O)c(c2ccccc2)c(=O)n(c3ccccn3)c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J02 compound treatment 0.228 -0.00587 -0.08 0.169 -0.059 -0.99 -0.7593 -0.7644 1140611 Maybridge4_003368 CCCCc1c(O)cc(c2ccccc2)n(Cc3ccccc3)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J03 compound treatment 0.266 0.0321 0.46 0.231 0.00303 0.05 0.3609 0.7806 3178591 Maybridge4_003369 Cc1ccc(cc1)C(=O)/C=C\2/NCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J04 compound treatment 0.264 0.0301 0.43 0.273 0.045 0.76 0.8391 0.9645 3178682 Maybridge4_003370 CC(=O)O[C@H]1[C@H](O[C@@H]2OC(C)(C)O[C@H]12)C(O)CO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J05 compound treatment 0.285 0.0511 0.73 0.264 0.036 0.6 0.9447 0.9955 1447328 Maybridge4_003371 CC(C)(C)C(=O)CC(Nc1ccccc1)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J06 compound treatment 0.342 0.108 1.55 0.259 0.031 0.52 1.4619 0.8958 1256088 Maybridge4_003372 C=CCC1(CCCCC1)NCCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J07 compound treatment 0.314 0.0801 1.15 0.281 0.053 0.89 1.4398 0.9922 1171716 Maybridge4_003373 CN1CCCC(C1)OC(=O)C2=C(C)NC3(O)c4ccccc4C(=O)C23O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J08 compound treatment 0.305 0.0711 1.02 0.295 0.067 1.13 1.5149 0.9987 1583880 Maybridge4_003374 CC(C)(C)Oc1ccc(CC(CO)NC(=O)OCC2c3ccccc3-c4ccccc24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J09 compound treatment 0.299 0.0651 0.93 0.312 0.084 1.41 1.656 0.9797 1604468 Maybridge4_003375 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccccc3Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J10 compound treatment 0.291 0.0571 0.82 0.244 0.016 0.27 0.768 0.8928 3064861 Maybridge4_003376 Cc1cc(OC(=O)c2ccco2)nc(SCc3c(Cl)cccc3Cl)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J11 compound treatment 0.335 0.101 1.45 0.314 0.086 1.44 2.0438 1.0 3178683 Maybridge4_003377 CC(C)C1(C)N2C(=O)c3ccccc3C2=NC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J12 compound treatment 0.33 0.0961 1.37 0.339 0.111 1.86 2.29 0.9888 3064862 Maybridge4_003378 O=C1CS/C(=N\C2CC2)/N1Cc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J13 compound treatment 0.275 0.0411 0.59 0.323 0.095 1.6 1.5438 0.9081 1167872 Maybridge4_003379 OC(=O)CNC(=O)CSc1ccccn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J14 compound treatment 0.296 0.0621 0.89 0.331 0.103 1.73 1.8511 0.9521 1457281 Maybridge4_003380 COCc1cc(OC(=O)N(C)C)nc(n1)c2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J15 compound treatment 0.329 0.0951 1.36 0.325 0.097 1.63 2.1137 0.996 3178684 Maybridge4_003381 CN(C)/C=N/n1cnc2sc3CCCCc3c2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J16 compound treatment 0.265 0.0311 0.45 0.278 0.05 0.84 0.9086 0.956 3178685 Maybridge4_003382 NC(=N)NC(=N)Nc1cc(n[nH]1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J17 compound treatment 0.303 0.0691 0.99 0.321 0.093 1.56 1.8032 0.9757 1294257 Maybridge4_003383 COc1cc(Cc2cc(OC)c(C)cc2OC)c(OC)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J18 compound treatment 0.307 0.0731 1.05 0.262 0.034 0.57 1.1435 0.9595 3178686 Maybridge4_003384 CCCCc1c(C)nc(nc1O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J19 compound treatment 0.062 -0.172 -2.46 0.059 -0.169 -2.84 -3.7437 -0.9975 3176922 Maybridge4_003385 OC[C@H]1O[C@H](C[C@@H]1O)n2cc(Br)c(=O)[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J20 compound treatment 0.265 0.0311 0.45 0.238 0.01 0.17 0.4339 0.9115 3064863 Maybridge4_003386 COc1cc(/C=N/c2ccc(Cl)cc2)ccc1OC(=O)/C=C/c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J21 compound treatment 0.291 0.0571 0.82 0.25 0.022 0.37 0.8392 0.9357 1169652 Maybridge4_003387 C1CN(CCO1)c2c3CCc4ccccc4-c3nc5ccccc25 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J22 compound treatment 0.194 -0.0399 -0.57 0.204 -0.024 -0.4 -0.6878 -0.9854 1608425 Maybridge4_003388 CCCC1=NN(C(=O)C(C)(C)C)C(=O)C1Cc2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J23 mock treatment 0.242 0.00812 0.12 0.241 0.013 0.22 0.2368 0.9562 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 J24 mock treatment 0.206 -0.0279 -0.4 0.197 -0.031 -0.52 -0.6495 -0.9914 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K01 compound treatment 0.28 0.0461 0.66 0.282 0.054 0.91 1.1078 0.9878 3064864 Maybridge4_003389 CSC1=N/C(=C\c2ccccc2O)/C(=O)N1Cc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K02 compound treatment 0.243 0.00912 0.13 0.236 0.00803 0.13 0.1876 0.9999 1422721 Maybridge4_003390 CCOC(=O)c1cnn(C(=O)COc2ccc(C)c3CCCc32)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K03 compound treatment 0.286 0.0521 0.75 0.273 0.045 0.76 1.0616 1.0 3178687 Maybridge4_003391 CSC1=N/C(=C\c2ccc(Cl)cc2)/C(=O)N1CCc3c[nH]c4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K04 compound treatment 0.328 0.0941 1.35 0.264 0.036 0.6 1.3796 0.9348 1502240 Maybridge4_003392 COC(=O)c1[nH]c(C(=O)OC)c(O)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K05 compound treatment 0.29 0.0561 0.8 0.243 0.015 0.25 0.7461 0.8866 3064865 Maybridge4_003393 COc1cccc(NC(=O)c2cnccc2C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K06 compound treatment 0.322 0.0881 1.26 0.243 0.015 0.25 1.0697 0.8321 3178688 Maybridge4_003394 CCOC(=O)/C=C(\C)/Nc1cccc(N\C(=C\C(=O)OCC)\C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K07 compound treatment 0.305 0.0711 1.02 0.24 0.012 0.2 0.8622 0.8312 3064866 Maybridge4_003395 FC(F)(F)c1ccc(cc1)c2nc(NC(=O)Nc3ccccc3)cs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K08 compound treatment 0.244 0.0101 0.14 0.168 -0.06 -1.01 -0.6093 -0.5992 1570272 Maybridge4_003396 CCC1N(CCc2c1[nH]c3ccccc23)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K09 compound treatment 0.338 0.104 1.49 0.289 0.061 1.02 1.7775 0.9833 3064867 Maybridge4_003397 FC(F)(F)c1ccncc1C(=O)NC(=O)Nc2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K10 compound treatment 0.308 0.0741 1.06 0.296 0.068 1.14 1.5571 0.9993 1687043 Maybridge4_003398 Cc1cc(C)c(COc2ccc3C(=O)CC(C)(C)Oc3c2C)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K11 compound treatment 0.306 0.0721 1.03 0.32 0.092 1.54 1.8217 0.9807 3064868 Maybridge4_003399 FC(F)(F)c1ccc(nc1)n2nc(oc2=O)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K12 compound treatment 0.172 -0.0619 -0.89 0.185 -0.043 -0.72 -1.1358 -0.9948 1713701 Maybridge4_003400 COc1cccc(c1)C2CCN(CC2)C(=O)c3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K13 compound treatment 0.279 0.0451 0.65 0.339 0.111 1.86 1.7741 0.8996 3064869 Maybridge4_003401 Cc1cc(C)c2c(=O)cc(oc2c1)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K14 compound treatment 0.328 0.0941 1.35 0.329 0.101 1.7 2.151 0.9935 3178689 Maybridge4_003402 FC(F)(F)c1ccc(cc1)C(=O)Nc2cccnc2Sc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K15 compound treatment 0.276 0.0421 0.6 0.31 0.082 1.38 1.3996 0.9313 1294252 Maybridge4_003403 CCOC(=O)c1cnn2c1nc(Sc3ccc(C)cc3)c4ccccc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K16 compound treatment 0.286 0.0521 0.75 0.303 0.075 1.26 1.4177 0.9687 1553374 Maybridge4_003404 C1CN(CCO1)c2nnc(c3ccccc3)c(n2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K17 compound treatment 0.23 -0.00387 -0.06 0.312 0.084 1.41 0.9581 0.6788 1663105 Maybridge4_003405 COc1ccc(Cc2cc(n[nH]c2=O)c3cccs3)c(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K18 compound treatment 0.28 0.0461 0.66 0.302 0.074 1.24 1.3451 0.9561 3064947 Maybridge4_003406 OC[C@H]1OC(Oc2ccc(cc2)c3coc4cc(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K19 compound treatment 0.296 0.0621 0.89 0.265 0.037 0.62 1.0678 0.9847 1252838 Maybridge4_003407 Cc1cc(C)n(NC(=S)NC2CCCC2)c(=O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K20 compound treatment 0.273 0.0391 0.56 0.273 0.045 0.76 0.9302 0.9891 1353357 Maybridge4_003408 S=C1CC(Sc2ccccc2N1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K21 compound treatment 0.264 0.0301 0.43 0.263 0.035 0.59 0.7204 0.9883 1332355 Maybridge4_003409 CC(=O)N1CCc2cc(NC(=S)NC3CCCCCC3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K22 compound treatment 0.23 -0.00387 -0.06 0.242 0.014 0.24 0.1273 0.5263 3064948 Maybridge4_003410 CNC(=O)c1cc(OC)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K23 mock treatment 0.221 -0.0129 -0.18 0.228 3.13E-5 0.0 -0.1298 -0.7051 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 K24 mock treatment 0.213 -0.0209 -0.3 0.189 -0.039 -0.65 -0.6736 -0.9369 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L01 compound treatment 0.226 -0.00787 -0.11 0.243 0.015 0.25 0.0987 0.3574 3064949 Maybridge4_003411 Cc1ncc(CO)c(/C=N/O)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L02 compound treatment 0.279 0.0451 0.65 0.268 0.04 0.67 0.9315 0.9998 2085598 Maybridge4_003412 CSc1sc(=S)sc1SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L03 compound treatment 0.235 0.00112 0.02 0.249 0.021 0.35 0.261 0.7386 1341478 Maybridge4_003413 NNC(=O)CC1(CC2CC3CC(C2)C1)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L04 compound treatment 0.292 0.0581 0.83 0.292 0.064 1.07 1.3478 0.992 1914392 Maybridge4_003414 O=C(c1ccccc1)n2ccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L05 compound treatment 0.253 0.0191 0.27 0.249 0.021 0.35 0.443 0.9921 3178690 Maybridge4_003415 C(SC1(CC2CC3CC(C2)C1)C3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L06 compound treatment 0.266 0.0321 0.46 0.244 0.016 0.27 0.5152 0.9675 1103414 Maybridge4_003416 OC(=O)C1CCCN1C(=O)OCC2c3ccccc3-c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L07 compound treatment 0.228 -0.00587 -0.08 0.288 0.06 1.01 0.653 0.6459 3064950 Maybridge4_003417 Oc1ccccc1c2cc(c(C#N)c(=O)[nH]2)c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L08 compound treatment 0.277 0.0431 0.62 0.271 0.043 0.72 0.9469 0.9969 3178691 Maybridge4_003418 FC(F)(F)c1cccc(c1)N2CCN(CC2)C3=Cc4ccccc4C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L09 compound treatment 0.234 1.25E-4 0.0 0.288 0.06 1.01 0.7137 0.7084 3064952 Maybridge4_003419 O=C(/C=C\1/NCCOC1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L10 compound treatment 0.278 0.0441 0.63 0.282 0.054 0.91 1.0875 0.9843 1604086 Maybridge4_003420 Clc1cccc(Cl)c1Cn2nnc(n2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L11 compound treatment 0.267 0.0331 0.47 0.268 0.04 0.67 0.8101 0.9854 1004954 Maybridge4_003421 N(C(=Nc1ccccc1)Nc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L12 compound treatment 0.216 -0.0179 -0.26 0.275 0.047 0.79 0.3774 0.4548 3178692 Maybridge4_003422 CC1CN(CC(C)O1)c2ccc(NC(=S)NCc3ccco3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L13 compound treatment 0.255 0.0211 0.3 0.294 0.066 1.11 0.9973 0.8682 3178693 Maybridge4_003423 FC(F)(F)C(NC(=O)Oc1ccccc1)(Oc2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L14 compound treatment 0.284 0.0501 0.72 0.285 0.057 0.96 1.1838 0.9899 3064954 Maybridge4_003424 COCc1cc(O)nc(SCC(=O)C(C)(C)C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L15 compound treatment 0.247 0.0131 0.19 0.296 0.068 1.14 0.9402 0.8125 1022292 Maybridge4_003425 O=C1NC(Cc2ccccc2)C(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L16 compound treatment 0.306 0.0721 1.03 0.245 0.017 0.29 0.9316 0.8702 3064955 Maybridge4_003426 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nnn(CC(=O)c3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L17 compound treatment 0.264 0.0301 0.43 0.27 0.042 0.71 0.8035 0.972 1517030 Maybridge4_003427 CC(=O)Oc1ccc(OC(=O)C)c2cc3c(OC(=O)C)ccc(OC(=O)C)c3cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L18 compound treatment 0.276 0.0421 0.6 0.252 0.024 0.4 0.7113 0.9809 3064957 Maybridge4_003428 CCN(CC)C(=S)Oc1nc(nc(C)c1CC(=C)C)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L19 compound treatment 0.268 0.0341 0.49 0.249 0.021 0.35 0.5947 0.9873 1414175 Maybridge4_003429 NNC(=O)C1C(C1c2ccccc2)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L20 compound treatment 0.21 -0.0239 -0.34 0.215 -0.013 -0.22 -0.3954 -0.9763 1151671 Maybridge4_003430 CC(C)(C)C(=O)CSc1nc2ccccc2c(=O)n1CC3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L21 compound treatment 0.267 0.0331 0.47 0.252 0.024 0.4 0.6202 0.9968 1294591 Maybridge4_003431 C1CCN(CC1)c2cc(nc3ccccc23)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L22 compound treatment 0.35 0.116 1.66 0.328 0.1 1.68 2.3617 1.0 3178694 Maybridge4_003432 CCCC1=NN(C(=O)/C=C/c2cccs2)C(=O)C1Cc3c(F)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L23 mock treatment 0.243 0.00912 0.13 0.263 0.035 0.59 0.508 0.8435 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 L24 mock treatment 0.202 -0.0319 -0.46 0.243 0.015 0.25 -0.144 -0.2763 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M01 compound treatment 0.305 0.0711 1.02 0.285 0.057 0.96 1.3962 0.9995 1614322 Maybridge4_003433 CC(C)NC(=O)N(Cc1ccccc1)Cc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M02 compound treatment 0.305 0.0711 1.02 0.263 0.035 0.59 1.1351 0.966 1632856 Maybridge4_003434 CCCCn1c(O)cc(C)c(C#N)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M03 compound treatment 0.339 0.105 1.5 0.352 0.124 2.08 2.5353 0.9873 3178695 Maybridge4_003435 CSC1=N/C(=C\Nc2cccc(Cl)c2)/C(=O)N1Cc3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M04 compound treatment 0.218 -0.0159 -0.23 0.219 -0.00897 -0.15 -0.267 -0.9801 1626500 Maybridge4_003436 S=C(NCC1CC1)Nc2ccc3[nH]ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M05 compound treatment 0.301 0.0671 0.96 0.238 0.01 0.17 0.798 0.8186 3178774 Maybridge4_003437 FC(F)(F)c1ccncc1C(=O)Nc2nc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M06 compound treatment 0.281 0.0471 0.67 0.242 0.014 0.24 0.6432 0.9008 3064958 Maybridge4_003438 NNC(=O)CC1=Nn2c(nnc2SC1)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M07 compound treatment 0.302 0.0681 0.97 0.282 0.054 0.91 1.3303 0.9994 3178775 Maybridge4_003439 CCN(Cc1cc(Cl)cc(Cl)c1)C(=O)c2cnc(OC)cc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M08 compound treatment 0.299 0.0651 0.93 0.254 0.026 0.44 0.9676 0.9405 1042478 Maybridge4_003440 CNc1cc(=O)n(C)c(=O)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M09 compound treatment 0.251 0.0171 0.24 0.302 0.074 1.24 1.0518 0.8305 3064959 Maybridge4_003441 Fc1ccc(NC(=O)c2cnccc2C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M10 compound treatment 0.286 0.0521 0.75 0.29 0.062 1.04 1.2634 0.9866 1313888 Maybridge4_003442 COc1cc(ccc1O)C2=NC(O)C(=O)Nc3ccc(Cl)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M11 compound treatment 0.287 0.0531 0.76 0.288 0.06 1.01 1.2498 0.9903 3064960 Maybridge4_003443 NNC(=O)c1cc(OCC(F)(F)F)nc(OCC(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M12 compound treatment 0.244 0.0101 0.14 0.289 0.061 1.02 0.8267 0.7991 3178776 Maybridge4_003444 Fc1ccc(cc1)c2nnc(CSCc3cccc4ccccc34)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M13 compound treatment 0.22 -0.0139 -0.2 0.183 -0.045 -0.75 -0.674 -0.8637 3178777 Maybridge4_003445 Clc1ccc(cc1)C(=O)CC(C(=O)c2ccccc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M14 compound treatment 0.252 0.0181 0.26 0.26 0.032 0.54 0.5635 0.9441 3064961 Maybridge4_003446 Nn1c(cc(c(C#N)c1=O)C(F)(F)F)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M15 compound treatment 0.233 -8.75E-4 -0.01 0.283 0.055 0.92 0.6443 0.6975 3178778 Maybridge4_003447 CCOC(=O)c1cnn2c1nc(Oc3cc(cc(c3)C(F)(F)F)C(F)(F)F)c4ccccc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M16 compound treatment 0.257 0.0231 0.33 0.272 0.044 0.74 0.7565 0.9343 1593342 Maybridge4_003448 CC(C)NC(=O)c1cccc2cccc(Sc3ccccc3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M17 compound treatment 0.29 0.0561 0.8 0.228 3.13E-5 0.0 0.568 0.7076 1609655 Maybridge4_003449 O=c1[nH]nc(cc1CC2CCCCC2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M18 compound treatment 0.303 0.0691 0.99 0.264 0.036 0.6 1.1268 0.9722 1690877 Maybridge4_003450 O=c1n(c2ccccc2)c(=O)n3C4CCC(C4)n31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M19 compound treatment 0.244 0.0101 0.14 0.198 -0.03 -0.5 -0.2533 -0.4839 1634815 Maybridge4_003451 Cc1cc(C)n(NC(=S)NCc2cccs2)c(=O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M20 compound treatment 0.245 0.0111 0.16 0.247 0.019 0.32 0.3384 0.9482 3065001 Maybridge4_003452 C1Sc2ccccc2C3=Nc4ccccc4SC(C13)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M21 compound treatment 0.266 0.0321 0.46 0.268 0.04 0.67 0.8 0.9828 3065002 Maybridge4_003453 CN(C)/C=C/C(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)c(C)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M22 compound treatment 0.235 0.00112 0.02 0.273 0.045 0.76 0.5458 0.722 3065003 Maybridge4_003454 NC(=O)c1cc(Cl)ccc1I 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M23 mock treatment 0.249 0.0151 0.22 0.269 0.041 0.69 0.6399 0.8865 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 M24 mock treatment 0.248 0.0141 0.2 0.225 -0.00297 -0.05 0.1076 0.5172 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N01 compound treatment 0.233 -8.75E-4 -0.01 0.286 0.058 0.97 0.6799 0.698 1588083 Maybridge4_003455 CC(=O)Oc1ccc(cc1)c2coc3cc(OC(=O)C)cc(OC(=O)C)c3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N02 compound treatment 0.21 -0.0239 -0.34 0.23 0.00203 0.03 -0.2174 -0.6334 1124592 Maybridge4_003456 CC1CC2(CCCCC2)N(Cc3ccccc13)S(=O)(=O)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N03 compound treatment 0.257 0.0231 0.33 0.255 0.027 0.45 0.5547 0.9879 3065004 Maybridge4_003457 CNC(=S)C1(CC2CC3CC(C2)C1)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N04 compound treatment 0.304 0.0701 1.0 0.266 0.038 0.64 1.1606 0.9762 1007974 Maybridge4_003458 O=C(Nc1ccccc1)OC2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N05 compound treatment 0.279 0.0451 0.65 0.251 0.023 0.39 0.7297 0.9699 3178779 Maybridge4_003459 CC(CNc1ccccc1)/C(=N/c2ccccc2)/Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N06 compound treatment 0.312 0.0781 1.12 0.232 0.00403 0.07 0.838 0.7485 1711036 Maybridge4_003460 CC1(C)c2ccccc2N3CC(=O)N(CC=C)C31C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N07 compound treatment 0.293 0.0591 0.85 0.257 0.029 0.49 0.9425 0.9657 854262 Maybridge4_003461 CC(N)(Cc1cccc(O)c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N08 compound treatment 0.295 0.0611 0.87 0.275 0.047 0.79 1.1764 0.9987 1129507 Maybridge4_003462 CC(N(C(=O)c1sc2ccccc2c1Cl)c3ccccn3)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N09 compound treatment 0.258 0.0241 0.35 0.265 0.037 0.62 0.6835 0.9614 1387784 Maybridge4_003463 COc1ccc(Sc2ccccc2COC(=O)C)c(c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N10 compound treatment 0.252 0.0181 0.26 0.271 0.043 0.72 0.694 0.9044 1366361 Maybridge4_003464 NNC(=O)Cn1nnc(n1)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N11 compound treatment 0.246 0.0121 0.17 0.277 0.049 0.82 0.7045 0.8377 3178780 Maybridge4_003465 CC1(C)NCS[C@H]1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N12 compound treatment 0.299 0.0651 0.93 0.232 0.00403 0.07 0.7065 0.7565 2078075 Maybridge4_003466 CC[n+]1c(C)csc1Nc2ccc(cc2)N3CC(C)OC(C)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N13 compound treatment 0.064 -0.17 -2.43 0.072 -0.156 -2.62 -3.5692 -0.9993 3178781 Maybridge4_003467 CCOC(NC(=O)Nc1ccc(Br)cc1)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N14 compound treatment 0.266 0.0321 0.46 0.298 0.07 1.18 1.1561 0.916 3065007 Maybridge4_003468 FC(F)(F)c1cc(=O)oc2cc(NC(=O)c3cc(Cl)cc(Cl)c3)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N15 compound treatment 0.204 -0.0299 -0.43 0.211 -0.017 -0.28 -0.5035 -0.9806 1675436 Maybridge4_003469 CCOC(=O)c1c(C)n(O)c2ccc3nonc3c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N16 compound treatment 0.298 0.0641 0.92 0.29 0.062 1.04 1.3848 0.998 1084802 Maybridge4_003470 CC(C)CCc1c(C)nc(N)nc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N17 compound treatment 0.295 0.0611 0.87 0.302 0.074 1.24 1.4968 0.9852 1383041 Maybridge4_003471 Clc1ccc(C(=O)N2CCC(CC2)NC(=O)c3ccccc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N18 compound treatment 0.261 0.0271 0.39 0.259 0.031 0.52 0.6426 0.9895 3065008 Maybridge4_003472 CS/C(=N/C(C)(C)C)/Nc1ccccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N19 compound treatment 0.284 0.0501 0.72 0.217 -0.011 -0.18 0.3768 0.509 1673966 Maybridge4_003473 Cc1c(NC(=O)C(C)(C)C)c(=O)n(c2ccccc2)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N20 compound treatment 0.278 0.0441 0.63 0.199 -0.029 -0.49 0.1025 0.1286 1479223 Maybridge4_003474 Cc1cc(Nc2ccc(F)c(Cl)c2)nc(NC(=O)C(C)(C)C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N21 compound treatment 0.279 0.0451 0.65 0.166 -0.062 -1.04 -0.279 -0.228 1920716 Maybridge4_003475 CC(C)COc1ccc(cc1)/C(=N\O)/c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N22 compound treatment 0.304 0.0701 1.0 0.252 0.024 0.4 0.9945 0.9199 3178782 Maybridge4_003476 CC(=C)CC1C(=NN(C1=O)S(=O)(=O)c2ccccc2Cl)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N23 mock treatment 0.28 0.0461 0.66 0.275 0.047 0.79 1.0247 0.996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 N24 mock treatment 0.242 0.00812 0.12 0.247 0.019 0.32 0.308 0.9063 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O01 compound treatment 0.24 0.00612 0.09 0.242 0.014 0.24 0.2285 0.9093 3178783 Maybridge4_003477 CSC1=N/C(=C\c2ccc(Cl)cc2)/C(=O)N1CCOc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O02 compound treatment 0.053 -0.181 -2.59 0.047 -0.181 -3.04 -3.9772 -0.9968 3065009 Maybridge4_003478 Cc1ccc(OCc2nnc(S)n2C3CCCCC3)c4CCCc41 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O03 compound treatment 0.326 0.0921 1.32 0.264 0.036 0.6 1.3594 0.9376 1042314 Maybridge4_003479 CNC(=O)Nc1cccc2cccnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O04 compound treatment 0.239 0.00512 0.07 0.142 -0.086 -1.44 -0.9684 -0.6703 1378461 Maybridge4_003480 S=C(NC1CCCCC1)Nc2ccc3[nH]ccc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O05 compound treatment 0.323 0.0891 1.27 0.275 0.047 0.79 1.4596 0.9734 3178784 Maybridge4_003481 FC(F)(F)c1ccncc1C(=O)NCc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O06 compound treatment 0.33 0.0961 1.37 0.277 0.049 0.82 1.5541 0.9699 3065010 Maybridge4_003482 CC(C)(C)C(=S)Nc1cccc(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O07 compound treatment 0.269 0.0351 0.5 0.267 0.039 0.66 0.8185 0.9914 3178785 Maybridge4_003483 COc1cccc(CNC(=O)c2cnc(OC)cc2C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O08 compound treatment 0.278 0.0441 0.63 0.233 0.00503 0.08 0.506 0.7946 1115300 Maybridge4_003484 NNC(=O)COc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O09 compound treatment 0.25 0.0161 0.23 0.263 0.035 0.59 0.5788 0.9165 3178786 Maybridge4_003485 NC(=O)C1=CN(CCC1C(F)(F)F)C(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O10 compound treatment 0.226 -0.00787 -0.11 0.212 -0.016 -0.27 -0.2692 -0.9258 1008942 Maybridge4_003486 Cc1cccc(NC(=O)Nc2cccc(C)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O11 compound treatment 0.214 -0.0199 -0.28 0.255 0.027 0.45 0.1198 0.2237 3178787 Maybridge4_003487 FC(F)(F)COc1ncccc1C(=O)NCc2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O12 compound treatment 0.218 -0.0159 -0.23 0.208 -0.02 -0.34 -0.3976 -0.982 1449652 Maybridge4_003488 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3ccc(CNC(=O)c4ccccc4)s3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O13 compound treatment 0.238 0.00412 0.06 0.207 -0.021 -0.35 -0.2071 -0.5805 3178788 Maybridge4_003489 COC(=O)c1cc2cc(Br)ccc2c(Br)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O14 compound treatment 0.223 -0.0109 -0.16 0.25 0.022 0.37 0.1515 0.3776 1523809 Maybridge4_003490 CCOC(=O)COc1nc(C)c(CC=C)c(C)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O15 compound treatment 0.231 -0.00287 -0.04 0.24 0.012 0.2 0.1137 0.5518 1444175 Maybridge4_003491 CCOC(=O)c1cnn2c1nc(N3CC(C)CC(C)C3)c4ccccc42 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O16 compound treatment 0.229 -0.00487 -0.07 0.175 -0.053 -0.89 -0.6779 -0.7602 3065040 Maybridge4_003492 O=C1/C(=C/c2ccc3ccccc3c2)/COc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O17 compound treatment 0.239 0.00512 0.07 0.239 0.011 0.19 0.1828 0.9178 3065041 Maybridge4_003493 Cc1cc(CO)cc(C)c1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O18 compound treatment 0.246 0.0121 0.17 0.268 0.04 0.67 0.5977 0.8614 1280927 Maybridge4_003494 O=c1n(c2ccccc2)c(=O)n3C4CC(C=C4)n31 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O19 compound treatment 0.129 -0.105 -1.5 0.074 -0.154 -2.58 -2.888 -0.9665 3065042 Maybridge4_003495 CC1=C(Sc2ccccc2N1)C(=O)Nn3cnc4cccc(F)c4c3=N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O20 compound treatment 0.251 0.0171 0.24 0.186 -0.042 -0.7 -0.3249 -0.4356 3065043 Maybridge4_003496 Cc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O21 compound treatment 0.25 0.0161 0.23 0.247 0.019 0.32 0.389 0.9872 1222795 Maybridge4_003497 CCOC(=O)c1cnn(C(=O)COc2ccc(cc2C(C)(C)C)C(C)(C)C)c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O22 compound treatment 0.285 0.0511 0.73 0.235 0.00703 0.12 0.6005 0.8107 3065044 Maybridge4_003498 Cc1cc(nc2CC(C)(C)C/C(=N/O)/c12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O23 mock treatment 0.192 -0.0419 -0.6 0.226 -0.00197 -0.03 -0.4469 -0.745 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 O24 mock treatment 0.216 -0.0179 -0.26 0.237 0.00903 0.15 -0.0736 -0.2476 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P01 compound treatment 0.179 -0.0549 -0.78 0.187 -0.041 -0.69 -1.0412 -0.9978 1411988 Maybridge4_003499 O=C(CC#N)NC(=O)NC1(CC2CC3CC(C2)C1)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P02 compound treatment 0.269 0.0351 0.5 0.225 -0.00297 -0.05 0.32 0.6339 1452749 Maybridge4_003500 CC1CC2(CCCCC2)N(Cc3ccccc13)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P03 compound treatment 0.213 -0.0209 -0.3 0.236 0.00803 0.13 -0.1158 -0.3535 2102798 Maybridge4_003501 COC(=O)/C=C\1/OC(=CC1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P04 compound treatment 0.275 0.0411 0.59 0.231 0.00303 0.05 0.4519 0.7654 1582498 Maybridge4_003502 CC(=O)NC(=O)NCc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P05 compound treatment 0.246 0.0121 0.17 0.249 0.021 0.35 0.3722 0.9465 3065047 Maybridge4_003503 CCOC(=O)CC1=NC(=O)CS1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P06 compound treatment 0.286 0.0521 0.75 0.251 0.023 0.39 0.8005 0.9532 1631994 Maybridge4_003504 Cc1ccc2N3CC(=O)N(Cc4ccccc4)C3(C)C(C)(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P07 compound treatment 0.239 0.00512 0.07 0.238 0.01 0.17 0.1709 0.9306 3065048 Maybridge4_003505 CC(=O)N1CC(O)C[C@H]1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P08 compound treatment 0.289 0.0551 0.79 0.231 0.00303 0.05 0.5935 0.7512 3178789 Maybridge4_003506 CN1N=C(C)C(Cc2c(Cl)cccc2Cl)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P09 compound treatment 0.23 -0.00387 -0.06 0.23 0.00203 0.03 -0.0151 -0.2318 1247915 Maybridge4_003507 O=C(Oc1ccc(Oc2ccccc2)cc1)N3CCC(CC3)OC(=O)n4ccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P10 compound treatment 0.227 -0.00687 -0.1 0.22 -0.00797 -0.13 -0.1641 -0.9886 3065049 Maybridge4_003508 CN(C)/N=C(\Cn1nnc(n1)N2CCCC2)/c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P11 compound treatment 0.232 -0.00187 -0.03 0.248 0.02 0.34 0.2188 0.6486 1294581 Maybridge4_003509 OC(=O)c1ccc2cc[nH]c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P12 compound treatment 0.169 -0.0649 -0.93 0.096 -0.132 -2.21 -2.2224 -0.9254 1153919 Maybridge4_003510 CC(C)(C)c1ccc(NC(=S)NCc2cccnc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P13 compound treatment 0.243 0.00912 0.13 0.233 0.00503 0.08 0.152 0.9778 3178790 Maybridge4_003511 CN(C)C(=O)NC(Nc1cc(C)on1)(C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P14 compound treatment 0.271 0.0371 0.53 0.231 0.00303 0.05 0.4115 0.7713 1634696 Maybridge4_003512 OCN1N=C(CCC1=O)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P15 compound treatment 0.234 1.25E-4 0.0 0.252 0.024 0.4 0.2865 0.7102 1538301 Maybridge4_003513 OC(=O)CCn1nc(Nc2ccccc2)n(c3ccccc3)c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P16 compound treatment 0.225 -0.00887 -0.13 0.194 -0.034 -0.57 -0.4929 -0.8439 3065050 Maybridge4_003514 COCc1nc(S)nc(O)c1Cc2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P17 compound treatment 0.254 0.0201 0.29 0.246 0.018 0.3 0.4175 0.9997 1358448 Maybridge4_003515 COc1ccccc1C2CCN(CC2)C(=O)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P18 compound treatment 0.215 -0.0189 -0.27 0.251 0.023 0.39 0.0824 0.1748 3065051 Maybridge4_003516 CC(C)(C)NC(=S)NCC1CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P19 compound treatment 0.29 0.0561 0.8 0.301 0.073 1.23 1.4344 0.9789 1357507 Maybridge4_003517 Clc1ccc(Nc2ccc(nn2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P20 compound treatment 0.286 0.0521 0.75 0.278 0.05 0.84 1.121 0.9982 1680143 Maybridge4_003518 Cc1cc(Nc2ccc(F)cc2)nc(SCc3c(Cl)cccc3Cl)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P21 compound treatment 0.273 0.0391 0.56 0.227 -9.69E-4 -0.02 0.3842 0.6863 1714479 Maybridge4_003519 CCOC(=O)N1CCN(CC(O)Cn2c(=O)n(C)c3ncn(C)c3c2=O)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P22 compound treatment 0.265 0.0311 0.45 0.28 0.052 0.87 0.9323 0.9511 3178866 Maybridge4_003520 CCCC1=NN(C(=O)C1CC=C)S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P23 mock treatment 0.224 -0.00987 -0.14 0.278 0.05 0.84 0.4939 0.58 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2058 P24 mock treatment 0.215 -0.0189 -0.27 0.268 0.04 0.67 0.2842 0.3925 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A01 compound treatment 0.209 -0.0135 -0.19 0.244 0.0341 0.57 0.2674 0.443 1585984 Maybridge4_003521 CC1=NN(C(=O)C2CC2)C(=O)C1Cc3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A02 compound treatment 0.231 0.00847 0.12 0.225 0.0151 0.25 0.2644 0.9432 1074928 Maybridge4_003522 S=c1cc(ss1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A03 compound treatment 0.29 0.0675 0.97 0.255 0.0451 0.76 1.2172 0.9927 3178867 Maybridge4_003523 Fc1ccc(N(C(=O)c2ccco2)C3=NCCCC(=O)S3)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A04 compound treatment 0.271 0.0485 0.69 0.27 0.0601 1.01 1.2031 0.9833 3065053 Maybridge4_003524 CN(C)C(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A05 compound treatment 0.209 -0.0135 -0.19 0.217 0.00706 0.12 -0.053 -0.2337 1513145 Maybridge4_003525 CCCc1nc(SCC(=O)c2ccc(Cl)cc2)nc(OC(=O)N(CC)CC)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A06 compound treatment 0.198 -0.0245 -0.35 0.252 0.0421 0.71 0.2511 0.3185 1235942 Maybridge4_003526 CC(C)(C)NC(=O)Nc1ccc2ccccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A07 compound treatment 0.196 -0.0265 -0.38 0.173 -0.0369 -0.62 -0.7067 -0.9723 1494176 Maybridge4_003527 Cc1cccc(NC(=S)Nc2ccccn2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A08 compound treatment 0.246 0.0235 0.34 0.225 0.0151 0.25 0.4161 0.9902 3065054 Maybridge4_003528 CNN1C(=O)c2cccc3cccc(C1=O)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A09 compound treatment 0.207 -0.0155 -0.22 0.201 -0.00894 -0.15 -0.2632 -0.9817 1077258 Maybridge4_003529 COc1ccc(cc1)C(CC(=O)c2ccccc2)CC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A10 compound treatment 0.231 0.00847 0.12 0.216 0.00606 0.1 0.1576 0.9962 3065056 Maybridge4_003530 Brc1ccc(cc1)C(=O)CC(CC(=O)c2ccc(Br)cc2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A11 compound treatment 0.23 0.00747 0.11 0.197 -0.0129 -0.22 -0.078 -0.3223 1076053 Maybridge4_003531 CN(C)CN1C(=O)c2ccccc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A12 compound treatment 0.212 -0.0105 -0.15 0.192 -0.0179 -0.3 -0.3194 -0.9488 1711456 Maybridge4_003532 O=C1CSC(N1c2cccnc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A13 compound treatment 0.255 0.0325 0.46 0.18 -0.0299 -0.5 -0.0269 -0.0393 3065058 Maybridge4_003533 Cc1c(C)c(NC(=O)/C=C/C(=O)O)c(C)c(C)c1NC(=O)/C=C/C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A14 compound treatment 0.186 -0.0365 -0.52 0.184 -0.0259 -0.44 -0.6773 -0.9959 3065084 Maybridge4_003534 CCc1ccc(cc1)n2nn[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A15 compound treatment 0.04 -0.183 -2.61 0.041 -0.169 -2.84 -3.8511 -0.9992 1012391 Maybridge4_003535 Clc1cccc(NC(=S)Nc2cccc(Cl)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A16 compound treatment 0.199 -0.0235 -0.34 0.216 0.00606 0.1 -0.1661 -0.4722 3065085 Maybridge4_003536 Cc1oc2ccccc2c1CNC(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A17 compound treatment 0.214 -0.00853 -0.12 0.208 -0.00194 -0.03 -0.1093 -0.8653 1164445 Maybridge4_003537 CCc1ccc(cc1)N2C(=O)CC(Sc3ccccc3N)C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A18 compound treatment 0.215 -0.00753 -0.11 0.223 0.0131 0.22 0.0789 0.3228 3065086 Maybridge4_003538 C/C(=N\CCc1ccc(Cl)cc1)/c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A19 compound treatment 0.211 -0.0115 -0.16 0.196 -0.0139 -0.23 -0.282 -0.9854 1020973 Maybridge4_003539 CC1(NC(=O)NC1=O)C2CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A20 compound treatment 0.207 -0.0155 -0.22 0.225 0.0151 0.25 0.0217 0.0644 3065087 Maybridge4_003540 Cc1ccc(NC(=C2C(=O)c3ccccc3C2=O)C#N)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A21 compound treatment 0.22 -0.00253 -0.04 0.226 0.0161 0.27 0.165 0.6067 3065088 Maybridge4_003541 CC(=O)Nc1nnc(o1)c2c(C)onc2c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A22 compound treatment 0.208 -0.0145 -0.21 0.208 -0.00194 -0.03 -0.17 -0.8079 3065089 Maybridge4_003542 Cc1cc(SCc2ccc(F)cc2)c(C)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A23 mock treatment 0.212 -0.0105 -0.15 0.183 -0.0269 -0.45 -0.4262 -0.8944 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 A24 mock treatment 0.2 -0.0225 -0.32 0.228 0.0181 0.3 -0.0135 -0.0306 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B01 compound treatment 0.3 0.0775 1.11 0.228 0.0181 0.3 0.9979 0.8686 1186435 Maybridge4_003543 CCc1ccc(O)c(c1)C2(O)C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B02 compound treatment 0.164 -0.0585 -0.84 0.173 -0.0369 -0.62 -1.0304 -0.9891 1389708 Maybridge4_003544 CCOc1ccc(NC23SCC(=O)C3CCc4ccccc42)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B03 compound treatment 0.272 0.0495 0.71 0.282 0.0721 1.21 1.3556 0.9674 1565816 Maybridge4_003545 CC(C)(C)c1ccc(cc1)C(=O)Oc2ccccc2CCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B04 compound treatment 0.153 -0.0695 -0.99 0.241 0.0311 0.52 -0.3346 -0.298 3178868 Maybridge4_003546 CCSC(=S)c1c(C)nn(c1O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B05 compound treatment 0.225 0.00247 0.04 0.187 -0.0229 -0.38 -0.2473 -0.6396 1315983 Maybridge4_003547 Clc1ccc(NC(C#N)c2ccccc2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B06 compound treatment 0.216 -0.00653 -0.09 0.263 0.0531 0.89 0.5637 0.6295 1049908 Maybridge4_003548 Fc1ccc(cc1)C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B07 compound treatment 0.23 0.00747 0.11 0.224 0.0141 0.24 0.2424 0.9358 3178869 Maybridge4_003549 NC(=S)Nc1ccccc1OC(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B08 compound treatment 0.233 0.0105 0.15 0.241 0.0311 0.52 0.4745 0.8748 3178870 Maybridge4_003550 COc1ccc(cc1)C(=O)NCc2c(C)onc2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B09 compound treatment 0.204 -0.0185 -0.27 0.195 -0.0149 -0.25 -0.3647 -0.9996 3065091 Maybridge4_003551 CC1CN(CC(C)O1)c2ccccc2OC(=O)Nc3ccc(OC(F)(F)F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B10 compound treatment 0.244 0.0215 0.31 0.228 0.0181 0.3 0.4315 1.0 3178871 Maybridge4_003552 Clc1ccc2nc(NC(=O)C3CN(C3)C(c4ccccc4)c5ccccc5)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B11 compound treatment 0.255 0.0325 0.46 0.228 0.0181 0.3 0.5428 0.9786 3178872 Maybridge4_003553 COc1ccc2cc(ccc2c1)C(C)C(=O)Nc3ccc(OC(F)(F)F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B12 compound treatment 0.233 0.0105 0.15 0.228 0.0181 0.3 0.3203 0.9471 3065092 Maybridge4_003554 CCc1ccnc(NC(=O)CC2(CC(=O)O)CCCCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B13 compound treatment 0.222 -5.31E-4 -0.01 0.213 0.00306 0.05 0.031 0.5961 1734850 Maybridge4_003555 COc1cc2N3C(=O)c4ccccc4C3(O)OC(=O)c2cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B14 compound treatment 0.192 -0.0305 -0.44 0.21 6.25E-5 0.0 -0.3081 -0.7054 3065093 Maybridge4_003556 Cc1nn(nc1CNC(=O)c2cc(F)cc3COCOc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B15 compound treatment 0.145 -0.0775 -1.11 0.126 -0.0839 -1.41 -1.7803 -0.993 3178873 Maybridge4_003557 NNC(=S)NCc1ccc(F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B16 compound treatment 0.22 -0.00253 -0.04 0.232 0.0221 0.37 0.2362 0.6349 3178874 Maybridge4_003558 Cc1nn(C)c2sc(cc12)C(=O)N(Cc3ccccn3)Cc4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B17 compound treatment 0.225 0.00247 0.04 0.238 0.0281 0.47 0.358 0.758 3065094 Maybridge4_003559 CN/1N=C(CS\C1=N\c2ccccc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B18 compound treatment 0.2 -0.0225 -0.32 0.214 0.00406 0.07 -0.1797 -0.5454 3178875 Maybridge4_003560 O=C(Nc1ccc(cc1)N2CCOCC2)c3cnc4ccccc4n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B19 compound treatment 0.212 -0.0105 -0.15 0.216 0.00606 0.1 -0.0346 -0.1901 1661129 Maybridge4_003561 Cc1ccc(CNC(=S)NCCO)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B20 compound treatment 0.217 -0.00553 -0.08 0.2 -0.00994 -0.17 -0.1739 -0.9419 3178876 Maybridge4_003562 CN1CCN(CC1)c2ccc(CNC(=O)c3ccc4OCCOc4c3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B21 compound treatment 0.234 0.0115 0.16 0.238 0.0281 0.47 0.449 0.9003 1246483 Maybridge4_003563 COc1ccc(cc1)C2C3CCc4ccccc4C3=NN2CCOC(=O)C5CC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B22 compound treatment 0.267 0.0445 0.64 0.209 -9.38E-4 -0.02 0.4386 0.6894 1407515 Maybridge4_003564 CCOC(=O)C1CCN(CC1)C(=O)CN2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B23 mock treatment 0.236 0.0135 0.19 0.215 0.00506 0.08 0.1963 0.9323 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 B24 mock treatment 0.265 0.0425 0.61 0.245 0.0351 0.59 0.8457 0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C01 compound treatment 0.247 0.0245 0.35 0.243 0.0331 0.55 0.6399 0.9753 3178877 Maybridge4_003565 CCCc1cc(O)nc(NC(=N)Nc2cccc(c2)C(F)(F)F)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C02 compound treatment 0.202 -0.0205 -0.29 0.21 6.25E-5 0.0 -0.2069 -0.7046 3065097 Maybridge4_003566 O=C1N(Nc2ccc(cc2)N3CCOCC3)C(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C03 compound treatment 0.222 -5.31E-4 -0.01 0.242 0.0321 0.54 0.3751 0.6971 3065098 Maybridge4_003567 CCCc1nc(SCC2CC2)nc(O)c1CC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C04 compound treatment 0.191 -0.0315 -0.45 0.18 -0.0299 -0.5 -0.6742 -0.9985 3178878 Maybridge4_003568 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccnn2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C05 compound treatment 0.231 0.00847 0.12 0.287 0.0771 1.29 1.0002 0.77 3178879 Maybridge4_003569 FC(F)(F)c1ccc(NC(=S)NC(=O)/C=C/c2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C06 compound treatment 0.09 -0.133 -1.9 0.103 -0.107 -1.79 -2.6096 -0.9996 1525321 Maybridge4_003570 CCc1ccc(NC(=S)Nc2ccccc2C(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C07 compound treatment 0.048 -0.175 -2.5 0.051 -0.159 -2.67 -3.6515 -0.9995 1218939 Maybridge4_003571 NNC(=S)NC1CCCCCCCCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C08 compound treatment 0.196 -0.0265 -0.38 0.193 -0.0169 -0.28 -0.4694 -0.9899 3065100 Maybridge4_003572 C(N1C2CCCCCN2c3ccccc13)c4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C09 compound treatment 0.275 0.0525 0.75 0.207 -0.00294 -0.05 0.4958 0.6592 3178880 Maybridge4_003573 O=C(CC(CC(=O)c1ccccc1)c2cccc3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C10 compound treatment 0.201 -0.0215 -0.31 0.211 0.00106 0.02 -0.2052 -0.665 3178881 Maybridge4_003574 Cn1cccc1C(=S)NC(=O)Nc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C11 compound treatment 0.249 0.0265 0.38 0.219 0.00906 0.15 0.3753 0.9197 3065101 Maybridge4_003575 CC1CC(CC(C)(C)C1)NC(=S)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C12 compound treatment 0.15 -0.0725 -1.04 0.186 -0.0239 -0.4 -1.0177 -0.9147 3065130 Maybridge4_003576 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C13 compound treatment 0.196 -0.0265 -0.38 0.206 -0.00394 -0.07 -0.3151 -0.8179 1084590 Maybridge4_003577 FC(F)(F)c1cccc(c1)n2c(=O)c3ccccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C14 compound treatment 0.069 -0.154 -2.2 0.064 -0.146 -2.45 -3.2848 -0.9985 3065131 Maybridge4_003578 COc1ccc(Nc2cc(ccc2Cl)C(F)(F)F)c(c1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C15 compound treatment 0.207 -0.0155 -0.22 0.215 0.00506 0.08 -0.097 -0.4078 1657408 Maybridge4_003579 CCOc1ccc(cc1)n2c(=O)c3cc4c(=O)n(c5ccc(OCC)cc5)c(=O)c4cc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C16 compound treatment 0.203 -0.0195 -0.28 0.219 0.00906 0.15 -0.09 -0.2829 3065132 Maybridge4_003580 C/C(=N\CCc1c[nH]c2ccccc12)/c3ccccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C17 compound treatment 0.2 -0.0225 -0.32 0.212 0.00206 0.03 -0.2034 -0.6275 3065134 Maybridge4_003581 CCc1ccc(NC2=NCCS2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C18 compound treatment 0.158 -0.0645 -0.92 0.178 -0.0319 -0.54 -1.0317 -0.9666 3065135 Maybridge4_003582 Clc1ccc(CCn2nn[nH]c2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C19 compound treatment 0.187 -0.0355 -0.51 0.195 -0.0149 -0.25 -0.5367 -0.947 1919115 Maybridge4_003583 COc1ccc(CC/N=C/c2ccccc2O)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C20 compound treatment 0.195 -0.0275 -0.39 0.223 0.0131 0.22 -0.1234 -0.2739 3065136 Maybridge4_003584 O=C1C(=C(Nc2cccnc2)C#N)C(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C21 compound treatment 0.168 -0.0545 -0.78 0.174 -0.0359 -0.6 -0.9781 -0.9919 1317332 Maybridge4_003585 CC(C)c1cccc(C(C)C)c1NC(=S)Nc2cccc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C22 compound treatment 0.192 -0.0305 -0.44 0.134 -0.0759 -1.27 -1.21 -0.8981 3065137 Maybridge4_003586 Clc1ccc(s1)C(=O)CC2OC(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C23 mock treatment 0.204 -0.0185 -0.27 0.203 -0.00694 -0.12 -0.2698 -0.9318 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 C24 mock treatment 0.218 -0.00453 -0.06 0.249 0.0391 0.66 0.4178 0.6341 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D01 compound treatment 0.199 -0.0235 -0.34 0.214 0.00406 0.07 -0.1898 -0.5526 1200638 Maybridge4_003587 Cc1ccc(cc1)N2C(C(=O)c3ccc(C)cc3O)c4ccccc4C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D02 compound treatment 0.202 -0.0205 -0.29 0.218 0.00806 0.14 -0.112 -0.3463 1391574 Maybridge4_003588 COc1ccc(Cc2nnc(N)o2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D03 compound treatment 0.23 0.00747 0.11 0.21 6.25E-5 0.0 0.0763 0.714 1057870 Maybridge4_003589 O=C1CC(=O)N(Cc2ccccc2)C(=O)N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D04 compound treatment 0.247 0.0245 0.35 0.251 0.0411 0.69 0.7348 0.9506 1006014 Maybridge4_003590 OC(=O)c1cc(O)nc(O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D05 compound treatment 0.259 0.0365 0.52 0.289 0.0791 1.33 1.3072 0.9168 3178961 Maybridge4_003591 Cc1ccc(F)cc1N2C(=O)COCC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D06 compound treatment 0.217 -0.00553 -0.08 0.286 0.0761 1.28 0.8468 0.662 3065138 Maybridge4_003592 N[C@@H](CC1CCCCC1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D07 compound treatment 0.197 -0.0255 -0.37 0.204 -0.00594 -0.1 -0.3287 -0.8683 3178962 Maybridge4_003593 OCC1(CO)CSC(=N1)Nc2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D08 compound treatment 0.235 0.0125 0.18 0.261 0.0511 0.86 0.7321 0.8363 3065139 Maybridge4_003594 Cc1onc(c1CNC(=O)C2CCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D09 compound treatment 0.22 -0.00253 -0.04 0.273 0.0631 1.06 0.7228 0.6825 3178963 Maybridge4_003595 FC(F)(F)Oc1ccc(NC(=O)Oc2ccccc2N3CCOCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D10 compound treatment 0.182 -0.0405 -0.58 0.278 0.0681 1.14 0.3978 0.3105 3178964 Maybridge4_003596 O=C(NCc1cc2ccccc2s1)C3CN(C3)C(c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D11 compound treatment 0.229 0.00647 0.09 0.245 0.0351 0.59 0.4816 0.8084 1719612 Maybridge4_003597 O=C1CC2(CCCc3ccccc32)C(=O)N1CN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D12 compound treatment 0.159 -0.0635 -0.91 0.22 0.0101 0.17 -0.5231 -0.566 3178965 Maybridge4_003598 Fc1cc(NC(=O)Nc2ccc(cc2)c3nc4ccccc4s3)c5OCOCc5c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D13 compound treatment 0.074 -0.149 -2.12 0.132 -0.0779 -1.31 -2.4272 -0.9729 3065140 Maybridge4_003599 CCCC(/N=C/c1cc(Cl)ccc1O)/N=C/c2cc(Cl)ccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D14 compound treatment 0.274 0.0515 0.74 0.295 0.0851 1.43 1.5301 0.9525 3178966 Maybridge4_003600 CC(C)c1ccc(NC(=O)c2cc(F)cc3COCOc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D15 compound treatment 0.212 -0.0105 -0.15 0.2 -0.00994 -0.17 -0.2245 -0.9987 3065142 Maybridge4_003601 Fc1ccc(Cn2nn[nH]c2=S)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D16 compound treatment 0.199 -0.0235 -0.34 0.277 0.0671 1.13 0.5579 0.4749 3178967 Maybridge4_003602 Cc1cc(CNC(=O)c2cc(C)n(C)n2)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D17 compound treatment 0.25 0.0275 0.39 0.247 0.0371 0.62 0.7177 0.9754 1581411 Maybridge4_003603 COc1ccc(NC(=S)N2CCCC(=N2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D18 compound treatment 0.221 -0.00153 -0.02 0.221 0.0111 0.19 0.1158 0.6194 3065143 Maybridge4_003604 COc1ccc(CC(=O)Nc2ccc(cc2)N3CCOCC3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D19 compound treatment 0.259 0.0365 0.52 0.224 0.0141 0.24 0.5357 0.9357 3178968 Maybridge4_003605 CN(C)C(=S)NCCC1=CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D20 compound treatment 0.206 -0.0165 -0.24 0.274 0.0641 1.08 0.5931 0.5387 3065144 Maybridge4_003606 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3ccc4OCCc4c3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D21 compound treatment 0.152 -0.0705 -1.01 0.167 -0.0429 -0.72 -1.223 -0.9864 3178969 Maybridge4_003607 CSc1ccc(cc1)C2C3CCCc4ccccc4C3=NN2CCO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D22 compound treatment 0.242 0.0195 0.28 0.248 0.0381 0.64 0.6486 0.9308 1607790 Maybridge4_003608 Fc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D23 mock treatment 0.228 0.00547 0.08 0.221 0.0111 0.19 0.1866 0.9262 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 D24 mock treatment 0.219 -0.00353 -0.05 0.203 -0.00694 -0.12 -0.1181 -0.9301 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E01 compound treatment 0.233 0.0105 0.15 0.234 0.0241 0.4 0.3915 0.9088 1514931 Maybridge4_003609 CC(C)(C)C(=O)Nc1nc(NC(=O)C(C)(C)C)nc(n1)c2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E02 compound treatment 0.143 -0.0795 -1.14 0.11 -0.0999 -1.68 -1.9905 -0.9821 3178970 Maybridge4_003610 CC1CC(CC(C)(C)C1)NC(=S)Nc2cc(C)ccc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E03 compound treatment 0.234 0.0115 0.16 0.217 0.00706 0.12 0.1998 0.9873 3065145 Maybridge4_003611 Cc1cccc(C)c1NC(=S)N2CCCC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E04 compound treatment 0.201 -0.0215 -0.31 0.205 -0.00494 -0.08 -0.2764 -0.8666 3178971 Maybridge4_003612 Oc1ccccc1/C=N/c2ccccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E05 compound treatment 0.232 0.00947 0.14 0.221 0.0111 0.19 0.2271 0.988 3178972 Maybridge4_003613 Oc1nc(S)nc(c1Cc2ccc(Cl)c(Cl)c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E06 compound treatment 0.287 0.0645 0.92 0.257 0.0471 0.79 1.2106 0.997 3065146 Maybridge4_003614 CCOc1ccc(NC(=S)NC(c2ccccc2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E07 compound treatment 0.229 0.00647 0.09 0.221 0.0111 0.19 0.1967 0.9483 3178973 Maybridge4_003615 Cc1cccc(C)c1NC2=NCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E08 compound treatment 0.108 -0.115 -1.64 0.127 -0.0829 -1.39 -2.1427 -0.9967 3065190 Maybridge4_003616 COc1cc(CN2C3CCCCCN3c4ccccc24)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E09 compound treatment 0.24 0.0175 0.25 0.284 0.0741 1.24 1.0557 0.8326 1023038 Maybridge4_003617 CN(C)C(=S)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E10 compound treatment 0.201 -0.0215 -0.31 0.262 0.0521 0.87 0.4001 0.4319 3065191 Maybridge4_003618 S=c1[nH]nnn1C2CC3CC2C4C=CCC34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E11 compound treatment 0.267 0.0445 0.64 0.211 0.00106 0.02 0.4624 0.7266 3065192 Maybridge4_003619 C(=N/c1ccccc1)\c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E12 compound treatment 0.204 -0.0185 -0.27 0.291 0.0811 1.36 0.7746 0.5588 3065193 Maybridge4_003620 CC(C)(C)c1ccc(/N=C/c2ccccc2O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E13 compound treatment 0.199 -0.0235 -0.34 0.249 0.0391 0.66 0.2256 0.3061 1597004 Maybridge4_003621 CN(C)C(=S)Nc1ccc(cc1)S(=O)(=O)N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E14 compound treatment 0.199 -0.0235 -0.34 0.289 0.0791 1.33 0.7003 0.5116 3065194 Maybridge4_003622 CCCNC(=O)OCN1C(=O)c2ccc(N)cc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E15 compound treatment 0.195 -0.0275 -0.39 0.197 -0.0129 -0.22 -0.432 -0.9606 3065195 Maybridge4_003623 Cc1cccc(NC2=NCCCS2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E16 compound treatment 0.244 0.0215 0.31 0.227 0.0171 0.29 0.4196 0.9994 3178974 Maybridge4_003624 O=C1CSC(N1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E17 compound treatment 0.257 0.0345 0.49 0.275 0.0651 1.09 1.1208 0.9354 3065196 Maybridge4_003625 COc1cc(NC(=S)N(C)C)c(OC)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E18 compound treatment 0.042 -0.181 -2.58 0.04 -0.17 -2.85 -3.8428 -0.9988 1132507 Maybridge4_003626 NNC(=S)NCCc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E19 compound treatment 0.22 -0.00253 -0.04 0.231 0.0211 0.35 0.2244 0.6314 3178975 Maybridge4_003627 Oc1ccc2ccccc2c1/C=N/Cc3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E20 compound treatment 0.182 -0.0405 -0.58 0.267 0.0571 0.96 0.2673 0.2387 1203485 Maybridge4_003628 CC(CC(=O)O)CC(=O)Nc1ccc(C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E21 compound treatment 0.218 -0.00453 -0.06 0.216 0.00606 0.1 0.0261 0.2165 3178976 Maybridge4_003629 CSc1cccc(NC(=S)NN(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E22 compound treatment 0.248 0.0255 0.36 0.244 0.0341 0.57 0.6619 0.9763 1385701 Maybridge4_003630 CC(C)(CC(=O)O)CC(=O)Nc1ccc(Cl)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E23 mock treatment 0.307 0.0845 1.21 0.226 0.0161 0.27 1.045 0.8441 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 E24 mock treatment 0.207 -0.0155 -0.22 0.194 -0.0159 -0.27 -0.3462 -0.9957 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F01 compound treatment 0.253 0.0305 0.44 0.209 -9.38E-4 -0.02 0.297 0.6811 1225773 Maybridge4_003631 Cc1cc(C)c(O)c(c1)C2(O)C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F02 compound treatment 0.227 0.00447 0.06 0.231 0.0211 0.35 0.2952 0.8216 1310128 Maybridge4_003632 OCCn1nc(O)ccc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F03 compound treatment 0.219 -0.00353 -0.05 0.249 0.0391 0.66 0.4279 0.6507 1400202 Maybridge4_003633 O=c1n(Cc2cccnc2)c(=S)[nH]c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F04 compound treatment 0.225 0.00247 0.04 0.303 0.0931 1.56 1.1294 0.7229 1055139 Maybridge4_003634 C(CC1CCNCC1)CC2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F05 compound treatment 0.237 0.0145 0.21 0.323 0.113 1.9 1.4882 0.7796 1205535 Maybridge4_003635 CN1N=C2C(CCc3ccccc23)C1c4ccc(F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F06 compound treatment 0.258 0.0355 0.51 0.227 0.0171 0.29 0.5612 0.9634 1475761 Maybridge4_003636 OC(=O)C1CCN(CC1)C(=O)OCC2c3ccccc3-c4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F07 compound treatment 0.226 0.00347 0.05 0.255 0.0451 0.76 0.5699 0.7519 3065197 Maybridge4_003637 COc1ccccc1NC2=NC(CO)(CO)CS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F08 compound treatment 0.332 0.109 1.57 0.297 0.0871 1.46 2.1405 0.9994 3178977 Maybridge4_003638 Cc1onc(c1CNS(=O)(=O)c2cccc(Cl)c2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F09 compound treatment 0.24 0.0175 0.25 0.25 0.0401 0.67 0.6521 0.9091 1679129 Maybridge4_003639 OCCn1c(=O)[nH]c2ccsc2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F10 compound treatment 0.284 0.0615 0.88 0.288 0.0781 1.31 1.5482 0.9812 3178978 Maybridge4_003640 O=C(Nc1ccc(cc1)n2cncn2)c3ccccc3N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F11 compound treatment 0.312 0.0895 1.28 0.265 0.0551 0.92 1.5584 0.9872 1432542 Maybridge4_003641 OC1(NC(=O)Cc2ccccc2Cl)C(=O)c3ccccc3C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F12 compound treatment 0.245 0.0225 0.32 0.345 0.135 2.27 1.8302 0.7994 3178979 Maybridge4_003642 CSc1c(c(N)nn1C(=O)C2CCC2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F13 compound treatment 0.228 0.00547 0.08 0.315 0.105 1.76 1.3022 0.7377 1512720 Maybridge4_003643 CN1OC(COC(=O)c2cc(Cl)cc(Cl)c2)CC31C4CC5CC(C4)CC3C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F14 compound treatment 0.234 0.0115 0.16 0.316 0.106 1.78 1.3748 0.769 3065199 Maybridge4_003644 NC(=O)c1ccc(NC(=O)c2cccc3OCCCOc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F15 compound treatment 0.271 0.0485 0.69 0.279 0.0691 1.16 1.3099 0.9698 3065200 Maybridge4_003645 Cc1ccc2nc(oc2c1)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F16 compound treatment 0.204 -0.0185 -0.27 0.254 0.0441 0.74 0.3355 0.4271 3178980 Maybridge4_003646 Cc1cc(nn1C)C(=O)NCC2COc3ccccc3O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F17 compound treatment 0.222 -5.31E-4 -0.01 0.252 0.0421 0.71 0.4938 0.6995 3065201 Maybridge4_003647 Cc1ccc(NC(=S)N2CCCC(=N2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F18 compound treatment 0.267 0.0445 0.64 0.265 0.0551 0.92 1.1033 0.9834 3178981 Maybridge4_003648 COc1ccc(CC(=O)Nc2ccc(cc2)c3cnco3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F19 compound treatment 0.263 0.0405 0.58 0.318 0.108 1.81 1.6918 0.8886 1597585 Maybridge4_003649 COc1ccc(CNC(=S)NCCO)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F20 compound treatment 0.217 -0.00553 -0.08 0.209 -9.38E-4 -0.02 -0.0671 -0.8315 3065202 Maybridge4_003650 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3sc(C)nc3C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F21 compound treatment 0.213 -0.00953 -0.14 0.277 0.0671 1.13 0.6995 0.617 2107603 Maybridge4_003651 O=C1/C(=C/c2ccccc2)/CCCc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F22 compound treatment 0.247 0.0245 0.35 0.24 0.0301 0.5 0.6043 0.984 3179070 Maybridge4_003652 O=C1NCCCCC1NS(=O)(=O)c2cccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F23 mock treatment 0.267 0.0445 0.64 0.221 0.0111 0.19 0.5811 0.8769 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 F24 mock treatment 0.189 -0.0335 -0.48 0.191 -0.0189 -0.32 -0.5639 -0.98 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G01 compound treatment 0.202 -0.0205 -0.29 0.262 0.0521 0.87 0.4102 0.445 3065203 Maybridge4_003653 CC(C)(C)C(=O)Nc1nc(NC(=O)C(C)(C)C)nc(n1)c2ccccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G02 compound treatment 0.051 -0.172 -2.45 0.053 -0.157 -2.63 -3.5975 -0.9994 3179071 Maybridge4_003654 Fc1cccc(NC(=S)NCc2ccc3OCOc3c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G03 compound treatment 0.128 -0.0945 -1.35 0.19 -0.0199 -0.33 -1.1927 -0.8563 1323302 Maybridge4_003655 CCCc1nc(nc(OC(=O)N(C)C)c1Cc2c(F)cccc2Cl)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G04 compound treatment 0.177 -0.0455 -0.65 0.187 -0.0229 -0.38 -0.7327 -0.9685 3065204 Maybridge4_003656 COC(=C(C#N)C#N)c1c(C)onc1c2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G05 compound treatment 0.243 0.0205 0.29 0.265 0.0551 0.92 0.8605 0.8876 3065205 Maybridge4_003657 CC(C)(C)C(=O)Cn1nnc(n1)c2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G06 compound treatment 0.24 0.0175 0.25 0.289 0.0791 1.33 1.115 0.8257 3179072 Maybridge4_003658 COC(=O)c1cc(NC(=O)/C=C/C(=O)O)ccc1N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G07 compound treatment 0.097 -0.126 -1.8 0.101 -0.109 -1.83 -2.5625 -1.0 3065206 Maybridge4_003659 Sc1nnc(Nc2ccccc2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G08 compound treatment 0.339 0.116 1.67 0.305 0.0951 1.6 2.3062 0.9998 3065300 Maybridge4_003660 CC1(C)NN(C(=O)N1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G09 compound treatment 0.3 0.0775 1.11 0.276 0.0661 1.11 1.5676 1.0 1076488 Maybridge4_003661 CCOc1ccc(cc1)N2CSC(=S)N(C2)c3ccc(OCC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G10 compound treatment 0.247 0.0245 0.35 0.216 0.00606 0.1 0.3194 0.8764 3065240 Maybridge4_003662 CC(C)N(Cc1ccccc1)C(=S)Nc2ccc(cc2)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G11 compound treatment 0.284 0.0615 0.88 0.3 0.0901 1.51 1.6906 0.9668 3065241 Maybridge4_003663 OCCNC(=S)c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G12 compound treatment 0.305 0.0825 1.18 0.265 0.0551 0.92 1.4876 0.9927 3065242 Maybridge4_003664 CC(C)(C)C(=O)Nc1ccc(cc1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G13 compound treatment 0.185 -0.0375 -0.54 0.221 0.0111 0.19 -0.2483 -0.4371 3065243 Maybridge4_003665 Cc1ccc2[nH]c(=S)n(C3CC4CC3C=C4)c(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G14 compound treatment 0.236 0.0135 0.19 0.225 0.0151 0.25 0.315 0.991 3065244 Maybridge4_003666 CC1(C)CC(=O)C=C(C1)NC(=O)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G15 compound treatment 0.281 0.0585 0.84 0.252 0.0421 0.71 1.0906 0.9964 3482133 Maybridge4_003667 CC(C)C(NS(=O)(=O)c1ccccc1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G16 compound treatment 0.215 -0.00753 -0.11 0.188 -0.0219 -0.37 -0.3365 -0.8772 3065245 Maybridge4_003668 Cc1ccc(cc1Cl)N2C(=O)N(C(=N)C2=S)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G17 compound treatment 0.185 -0.0375 -0.54 0.288 0.0781 1.31 0.5469 0.3862 3179073 Maybridge4_003669 Cc1c(C)c(C)c(CSc2cccc(NC(=O)/C=C/C(=O)O)c2)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G18 compound treatment 0.235 0.0125 0.18 0.231 0.0211 0.35 0.3761 0.9498 3065246 Maybridge4_003670 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G19 compound treatment 0.23 0.00747 0.11 0.221 0.0111 0.19 0.2068 0.9655 3179074 Maybridge4_003671 CN(CC(=O)O)C(=S)c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G20 compound treatment 0.236 0.0135 0.19 0.226 0.0161 0.27 0.3269 0.9864 3179075 Maybridge4_003672 CSc1ccc(/C=N/n2c(=O)oc3ccccc3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G21 compound treatment 0.186 -0.0365 -0.52 0.231 0.0211 0.35 -0.1195 -0.1894 3065247 Maybridge4_003673 CN(C)NC(=S)Nc1ccc(C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G22 compound treatment 0.184 -0.0385 -0.55 0.208 -0.00194 -0.03 -0.4127 -0.7475 1356260 Maybridge4_003674 N#Cc1ccc(cc1)C(N2CCSCC2)N3CCSCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G23 mock treatment 0.212 -0.0105 -0.15 0.227 0.0171 0.29 0.096 0.2966 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 G24 mock treatment 0.213 -0.00953 -0.14 0.185 -0.0249 -0.42 -0.3924 -0.8913 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H01 compound treatment 0.214 -0.00853 -0.12 0.244 0.0341 0.57 0.318 0.5439 3065248 Maybridge4_003675 Clc1cccc(Cl)c1CSCc2cc3ccccc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H02 compound treatment 0.212 -0.0105 -0.15 0.215 0.00506 0.08 -0.0464 -0.2685 1495324 Maybridge4_003676 CSCC(O)Cn1nc(O)ccc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H03 compound treatment 0.213 -0.00953 -0.14 0.221 0.0111 0.19 0.0349 0.1515 3065250 Maybridge4_003677 CN(C)/C=C/1\C(=O)N(C)N=C1c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H04 compound treatment 0.23 0.00747 0.11 0.212 0.00206 0.03 0.1 0.8906 3179076 Maybridge4_003678 NC(=N)c1ccc(cc1)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H05 compound treatment 0.247 0.0245 0.35 0.296 0.0861 1.44 1.2689 0.8537 3065251 Maybridge4_003679 NC1=C(C#N)C(C#N)(C#N)C2CCCC(=C21)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H06 compound treatment 0.251 0.0285 0.41 0.254 0.0441 0.74 0.8109 0.9605 3179077 Maybridge4_003680 CC(C)(C)OC(=O)N1CCCC[C@@H]1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H07 compound treatment 0.276 0.0535 0.76 0.283 0.0731 1.23 1.4079 0.9742 3179078 Maybridge4_003681 FC(F)(F)c1ccc(cc1)C(=O)NCc2csc3ccc(Cl)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H08 compound treatment 0.308 0.0855 1.22 0.315 0.105 1.76 2.1113 0.984 3065253 Maybridge4_003682 Cc1onc(c1CNC(=O)Nc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H09 compound treatment 0.269 0.0465 0.66 0.245 0.0351 0.59 0.8861 0.9982 3179079 Maybridge4_003683 Fc1cccc(Cl)c1/C=N/Cc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H10 compound treatment 0.267 0.0445 0.64 0.275 0.0651 1.09 1.2219 0.9669 3065255 Maybridge4_003684 OC(=O)CC1(CC(=O)NCc2ccccn2)CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H11 compound treatment 0.235 0.0125 0.18 0.248 0.0381 0.64 0.5778 0.8712 1354093 Maybridge4_003685 CC(=O)Nc1ccccc1OCCN(Cc2ccccc2)C(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H12 compound treatment 0.325 0.102 1.47 0.33 0.12 2.02 2.4613 0.9878 3179080 Maybridge4_003686 CC1(C)Cc2cccc(C(=O)N3CCC(CC3)c4c[nH]c5ccccc45)c2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H13 compound treatment 0.255 0.0325 0.46 0.236 0.0261 0.44 0.6377 0.9996 1211536 Maybridge4_003687 COc1ccc(cc1)C(=O)CC(C(=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H14 compound treatment 0.296 0.0735 1.05 0.318 0.108 1.81 2.0256 0.9663 3179081 Maybridge4_003688 FC(F)(SCc1c(Cl)cccc1Cl)C(=O)c2cnc3ccccn23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H15 compound treatment 0.277 0.0545 0.78 0.247 0.0371 0.62 0.9908 0.9938 3065256 Maybridge4_003689 O=C1/C(=C/C2CCCCC2)/CCCc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H16 compound treatment 0.259 0.0365 0.52 0.282 0.0721 1.21 1.2241 0.9293 3179082 Maybridge4_003690 Cc1cc(nn1C)C(=O)NCc2cc(F)cc3COCOc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H17 compound treatment 0.231 0.00847 0.12 0.253 0.0431 0.72 0.5967 0.8143 3179083 Maybridge4_003691 CC1OCN(Cn2c1nc3ccc(Cl)cc23)c4ccc(OC(F)(F)F)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H18 compound treatment 0.228 0.00547 0.08 0.278 0.0681 1.14 0.8631 0.7538 3065257 Maybridge4_003692 COc1ccc(CC(=O)N2CCN(CC2)c3ncccn3)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H19 compound treatment 0.21 -0.0125 -0.18 0.179 -0.0309 -0.52 -0.4939 -0.8991 3065258 Maybridge4_003693 COc1ccc(CNC(=S)NN)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H20 compound treatment 0.256 0.0335 0.48 0.244 0.0341 0.57 0.7428 0.9961 3179084 Maybridge4_003694 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3cccc4nonc34)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H21 compound treatment 0.184 -0.0385 -0.55 0.246 0.0361 0.61 0.0383 0.0468 1247395 Maybridge4_003695 CN1N=C2C(CCCc3ccccc23)C1c4ccc5OCOc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H22 compound treatment 0.243 0.0205 0.29 0.263 0.0531 0.89 0.8368 0.8926 3065259 Maybridge4_003696 Cc1cc(c(C)s1)S(=O)(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H23 mock treatment 0.231 0.00847 0.12 0.224 0.0141 0.24 0.2525 0.952 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 H24 mock treatment 0.215 -0.00753 -0.11 0.182 -0.0279 -0.47 -0.4077 -0.8475 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I01 compound treatment 0.235 0.0125 0.18 0.222 0.0121 0.2 0.2693 0.998 1362748 Maybridge4_003697 CCc1cccc(C)c1NC(=S)NCCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I02 compound treatment 0.093 -0.13 -1.85 0.074 -0.136 -2.28 -2.9234 -0.9947 3065301 Maybridge4_003698 Clc1ccc(NC(=S)NC2CCCC2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I03 compound treatment 0.207 -0.0155 -0.22 0.242 0.0321 0.54 0.2234 0.3838 1186254 Maybridge4_003699 CCN(CC)C(=O)Oc1nc(nc(COC)c1CC2CC2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I04 compound treatment 0.198 -0.0245 -0.35 0.228 0.0181 0.3 -0.0337 -0.0728 3065303 Maybridge4_003700 C1CN=C(Nc2ccccc2c3ccccc3)S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I05 compound treatment 0.245 0.0225 0.32 0.286 0.0761 1.28 1.13 0.8583 1358941 Maybridge4_003701 Clc1ccc(cc1)c2csc(NC(=S)NC(=O)C3CC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I06 compound treatment 0.249 0.0265 0.38 0.282 0.0721 1.21 1.123 0.8861 3065304 Maybridge4_003702 CCOC(=O)c1ccc(Cl)c(NC(=S)N(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I07 compound treatment 0.191 -0.0315 -0.45 0.221 0.0111 0.19 -0.1876 -0.3847 1536146 Maybridge4_003703 S=C(NCc1ccccc1)NC(Cc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I08 compound treatment 0.047 -0.176 -2.51 0.057 -0.153 -2.57 -3.5904 -0.9999 3065305 Maybridge4_003704 FC(F)(F)c1cc(NC(=S)NC2CCCCC2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I09 compound treatment 0.219 -0.00353 -0.05 0.21 6.25E-5 0.0 -0.035 -0.6923 3179085 Maybridge4_003705 S=C1SCN(Cc2ccccc2)CN1Cc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I10 compound treatment 0.228 0.00547 0.08 0.282 0.0721 1.21 0.9106 0.7513 3179086 Maybridge4_003706 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NC(=S)Nc2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I11 compound treatment 0.273 0.0505 0.72 0.294 0.0841 1.41 1.5081 0.9516 3065306 Maybridge4_003707 COc1ccc(CCNC(=S)NC(=O)c2ccc(Cl)cc2Cl)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I12 compound treatment 0.214 -0.00853 -0.12 0.279 0.0691 1.16 0.7334 0.6292 3179087 Maybridge4_003708 COc1ccc(/C=N/c2ccc(cc2)C(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I13 compound treatment 0.248 0.0255 0.36 0.308 0.0981 1.65 1.4214 0.8432 3065307 Maybridge4_003709 Clc1cccc(Cl)c1/N=C\2/NCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I14 compound treatment 0.213 -0.00953 -0.14 0.329 0.119 2.0 1.3166 0.6573 1044972 Maybridge4_003710 NNC(=O)Cc1cccc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I15 compound treatment 0.106 -0.117 -1.67 0.107 -0.103 -1.73 -2.4003 -0.9998 3065308 Maybridge4_003711 Cc1ccc2[nH]c(nc2c1)c3cccc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I16 compound treatment 0.184 -0.0385 -0.55 0.177 -0.0329 -0.55 -0.7806 -1.0 3179088 Maybridge4_003712 OC(=O)CC(CC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I17 compound treatment 0.092 -0.131 -1.87 0.102 -0.108 -1.81 -2.6012 -0.9999 3179089 Maybridge4_003713 CC(C)c1ccc2c(CCC3C(C)(CNC(=O)/C=C/C(=O)O)CCCC32C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I18 compound treatment 0.296 0.0735 1.05 0.266 0.0561 0.94 1.4084 0.9985 1216891 Maybridge4_003714 Ic1ccc(NC(=O)Cc2cccc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I19 compound treatment 0.046 -0.177 -2.53 0.043 -0.167 -2.8 -3.7667 -0.9987 3065310 Maybridge4_003715 Fc1ccc(NC2=NCCN2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I20 compound treatment 0.24 0.0175 0.25 0.228 0.0181 0.3 0.3911 0.9954 3179090 Maybridge4_003716 CC1CC(=O)N(C1=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I21 compound treatment 0.178 -0.0445 -0.64 0.178 -0.0319 -0.54 -0.8294 -0.9963 3065312 Maybridge4_003717 COc1ccc(/N=C/c2ccc(cc2)N(C)CCC#N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I22 compound treatment 0.203 -0.0195 -0.28 0.205 -0.00494 -0.08 -0.2561 -0.879 1341869 Maybridge4_003718 C1CN(CCO1)C(N2CCOCC2)c3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I23 mock treatment 0.249 0.0265 0.38 0.191 -0.0189 -0.32 0.043 0.0869 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 I24 mock treatment 0.182 -0.0405 -0.58 0.197 -0.0129 -0.22 -0.5635 -0.9102 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J01 compound treatment 0.232 0.00947 0.14 0.231 0.0211 0.35 0.3457 0.9133 1699626 Maybridge4_003719 CC(C)(C)c1ccc(NC(=O)N2CCOCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J02 compound treatment 0.203 -0.0195 -0.28 0.23 0.0201 0.34 0.0406 0.0927 1369792 Maybridge4_003720 Fc1ccc(cc1)C2=NN(CCC2)C(=S)NCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J03 compound treatment 0.171 -0.0515 -0.74 0.171 -0.0389 -0.65 -0.9833 -0.9982 3065313 Maybridge4_003721 Cc1onc(c1c2nc3ccc(I)cc3c(=O)o2)c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J04 compound treatment 0.09 -0.133 -1.9 0.11 -0.0999 -1.68 -2.5265 -0.9981 1076697 Maybridge4_003722 CC1=NN(C(=O)C1)c2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J05 compound treatment 0.045 -0.178 -2.54 0.058 -0.152 -2.55 -3.5988 -1.0 3179091 Maybridge4_003723 Cn1c(=O)sn(c2ccccc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J06 compound treatment 0.261 0.0385 0.55 0.294 0.0841 1.41 1.3867 0.9157 3179172 Maybridge4_003724 Clc1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J07 compound treatment 0.249 0.0265 0.38 0.25 0.0401 0.67 0.7432 0.9631 3065315 Maybridge4_003725 Cc1ccc(cc1)C(=O)CC(C(=O)c2ccc(cc2)C(F)(F)F)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J08 compound treatment 0.279 0.0565 0.81 0.26 0.0501 0.84 1.1653 0.9998 3179173 Maybridge4_003726 Cc1onc(c1CNC(=O)NC2CCN(CC2)C(=O)OCc3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J09 compound treatment 0.267 0.0445 0.64 0.284 0.0741 1.24 1.3287 0.9516 1543567 Maybridge4_003727 CN1N=C2C(CCc3ccccc23)C1c4ccc(C#N)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J10 compound treatment 0.248 0.0255 0.36 0.264 0.0541 0.91 0.8992 0.9196 3065317 Maybridge4_003728 Cc1noc(c1NC(=O)Nc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J11 compound treatment 0.308 0.0855 1.22 0.312 0.102 1.71 2.0757 0.9863 3179174 Maybridge4_003729 CCOC(=O)C1C(CC(=CC1=O)c2ccc3ccccc3c2)c4ccc(cc4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J12 compound treatment 0.303 0.0805 1.15 0.321 0.111 1.86 2.132 0.9732 3065318 Maybridge4_003730 CC1(C)Cc2cccc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J13 compound treatment 0.229 0.00647 0.09 0.314 0.104 1.75 1.3004 0.7435 1351189 Maybridge4_003731 CC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J14 compound treatment 0.294 0.0715 1.02 0.311 0.101 1.7 1.9223 0.9706 3065319 Maybridge4_003732 CC1(C)CCc2cc(ccc2O1)S(=O)(=O)N(Cc3ccccn3)Cc4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J15 compound treatment 0.248 0.0255 0.36 0.218 0.00806 0.14 0.3533 0.9091 3179175 Maybridge4_003733 COc1ccc(C/N=C/c2ccc(cc2)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J16 compound treatment 0.275 0.0525 0.75 0.288 0.0781 1.31 1.4571 0.965 3065320 Maybridge4_003734 Cc1cc(nn1C)C(=O)NCc2cccn2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J17 compound treatment 0.264 0.0415 0.59 0.308 0.0981 1.65 1.5832 0.905 3179176 Maybridge4_003735 FC(F)(F)c1ccc(/C=C(\C#N)/c2csc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J18 compound treatment 0.219 -0.00353 -0.05 0.262 0.0521 0.87 0.5822 0.6651 3065361 Maybridge4_003736 COc1ccc(CC(=O)NCc2cc(C)oc2C(F)(F)F)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J19 compound treatment 0.299 0.0765 1.09 0.284 0.0741 1.24 1.6524 0.998 3065362 Maybridge4_003737 CCOc1cccc(/C=N/c2nnc(SC)s2)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J20 compound treatment 0.23 0.00747 0.11 0.222 0.0121 0.2 0.2187 0.9554 3065363 Maybridge4_003738 COC(=O)c1cc(oc1C)S(=O)(=O)N2CCSC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J21 compound treatment 0.256 0.0335 0.48 0.247 0.0371 0.62 0.7784 0.9916 3065364 Maybridge4_003739 Cn1c2NCN(CC3CC3)Cc2c(=O)n(C)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J22 compound treatment 0.226 0.00347 0.05 0.258 0.0481 0.81 0.6055 0.7492 3065366 Maybridge4_003740 O=C(NC1CCCCNC1=O)c2csc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J23 mock treatment 0.251 0.0285 0.41 0.235 0.0251 0.42 0.5854 0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 J24 mock treatment 0.194 -0.0285 -0.41 0.189 -0.0209 -0.35 -0.5371 -0.9972 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K01 compound treatment 0.231 0.00847 0.12 0.203 -0.00694 -0.12 0.0033 0.0198 1480507 Maybridge4_003741 Clc1ccc(Oc2ccccc2NS(=O)(=O)c3ccc(NC(=O)C4CC4)cc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K02 compound treatment 0.205 -0.0175 -0.25 0.259 0.0491 0.82 0.405 0.4704 3065367 Maybridge4_003742 CN(C)c1ccc(/C=N/N)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K03 compound treatment 0.212 -0.0105 -0.15 0.246 0.0361 0.61 0.3215 0.5154 1560480 Maybridge4_003743 Cc1c(Cc2ccc(F)cc2)c(=O)oc3cc(O)ccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K04 compound treatment 0.258 0.0355 0.51 0.331 0.121 2.03 1.7955 0.8573 3179177 Maybridge4_003744 CC(C)(C)NC(=O)Nc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K05 compound treatment 0.199 -0.0235 -0.34 0.195 -0.0149 -0.25 -0.4153 -0.9895 1436913 Maybridge4_003745 COc1ccccc1NC(=S)NC(c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K06 compound treatment 0.262 0.0395 0.56 0.274 0.0641 1.08 1.1595 0.9548 1517059 Maybridge4_003746 CCOc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K07 compound treatment 0.241 0.0185 0.26 0.249 0.0391 0.66 0.6504 0.9201 3179178 Maybridge4_003747 C1CCCCCC(CCCCC1)/N=C/c2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K08 compound treatment 0.086 -0.137 -1.95 0.083 -0.127 -2.13 -2.8874 -0.9991 1293740 Maybridge4_003748 Cc1cc(C)cc(NC(=S)NC2CCCCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K09 compound treatment 0.04 -0.183 -2.61 0.042 -0.168 -2.82 -3.8393 -0.9993 1032487 Maybridge4_003749 CCN1CSC(=S)N(CC)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K10 compound treatment 0.251 0.0285 0.41 0.272 0.0621 1.04 1.0245 0.916 1046043 Maybridge4_003750 NC(=N)SCCN1C(=O)c2ccccc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K11 compound treatment 0.239 0.0165 0.24 0.27 0.0601 1.01 0.8794 0.8495 1157754 Maybridge4_003751 COc1ccc(CCNC(=S)N(C)C)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K12 compound treatment 0.285 0.0625 0.89 0.219 0.00906 0.15 0.7394 0.8157 3179179 Maybridge4_003752 Cc1nc2ccccc2c(=O)n1/N=C/c3ccc(Cl)c(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K13 compound treatment 0.276 0.0535 0.76 0.243 0.0331 0.55 0.9332 0.9876 1244335 Maybridge4_003753 S=C(NCc1cccnc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K14 compound treatment 0.301 0.0785 1.12 0.3 0.0901 1.51 1.8625 0.9893 3179180 Maybridge4_003754 O=C(NCCCN1CCOCC1)NCc2cccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K15 compound treatment 0.24 0.0175 0.25 0.224 0.0141 0.24 0.3436 0.9996 3065370 Maybridge4_003755 COc1cc(NC(=S)N)c(OC)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K16 compound treatment 0.187 -0.0355 -0.51 0.232 0.0221 0.37 -0.0975 -0.1551 3179181 Maybridge4_003756 FC(F)(F)c1cccc(NC(=O)N2CCOC32CCCCC3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K17 compound treatment 0.123 -0.0995 -1.42 0.139 -0.0709 -1.19 -1.8486 -0.9961 3065371 Maybridge4_003757 Cc1c(C)c(C)c(CNC(=S)NN)c(C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K18 compound treatment 0.208 -0.0145 -0.21 0.23 0.0201 0.34 0.0911 0.2303 3179182 Maybridge4_003758 O=c1oc(nc2ccccc12)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K19 compound treatment 0.227 0.00447 0.06 0.273 0.0631 1.06 0.7936 0.7484 3179183 Maybridge4_003759 CC/C(=N\Cc1ccc(C#N)cc1)/c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K20 compound treatment 0.241 0.0185 0.26 0.218 0.00806 0.14 0.2825 0.9517 1593893 Maybridge4_003760 NC(=O)C1C(C2CC1C=C2)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K21 compound treatment 0.227 0.00447 0.06 0.203 -0.00694 -0.12 -0.0371 -0.2796 3179184 Maybridge4_003761 Fc1cccc(NC2=NCCS2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K22 compound treatment 0.206 -0.0165 -0.24 0.223 0.0131 0.22 -0.0122 -0.0378 3065373 Maybridge4_003762 Clc1ccc(cc1)C(=O)OCCc2csc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K23 mock treatment 0.205 -0.0175 -0.25 0.213 0.00306 0.05 -0.141 -0.5507 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 K24 mock treatment 0.185 -0.0375 -0.54 0.18 -0.0299 -0.5 -0.7349 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L01 compound treatment 0.215 -0.00753 -0.11 0.22 0.0101 0.17 0.0432 0.2159 3179185 Maybridge4_003763 CN(C)/C=C/1\SC(=O)N(C1=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L02 compound treatment 0.224 0.00147 0.02 0.223 0.0131 0.22 0.1699 0.7713 1281043 Maybridge4_003764 CC(C)c1ccc(NC(=S)N2CCCC(=N2)c3ccc(F)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L03 compound treatment 0.212 -0.0105 -0.15 0.222 0.0121 0.2 0.0366 0.1452 3065374 Maybridge4_003765 O=C/1N(C(=N\C1=C\c2ccccc2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L04 compound treatment 0.183 -0.0395 -0.57 0.198 -0.0119 -0.2 -0.5415 -0.9027 3065375 Maybridge4_003766 OC(=O)c1cccnc1S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L05 compound treatment 0.187 -0.0355 -0.51 0.199 -0.0109 -0.18 -0.4892 -0.9053 3179186 Maybridge4_003767 FC(F)(F)c1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L06 compound treatment 0.272 0.0495 0.71 0.286 0.0761 1.28 1.4031 0.9613 1719441 Maybridge4_003768 Cc1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L07 compound treatment 0.258 0.0355 0.51 0.272 0.0621 1.04 1.0953 0.9453 3179187 Maybridge4_003769 FC(F)(F)Oc1ccc(NC(=O)OCCc2csc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L08 compound treatment 0.289 0.0665 0.95 0.287 0.0771 1.29 1.5869 0.9885 3179188 Maybridge4_003770 C1COc2cc(ccc2O1)c3nc(cs3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L09 compound treatment 0.214 -0.00853 -0.12 0.218 0.00806 0.14 0.0094 0.0516 3065376 Maybridge4_003771 Clc1ccc(cc1)c2nnc(c3ccccc3)c(=O)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L10 compound treatment 0.242 0.0195 0.28 0.221 0.0111 0.19 0.3282 0.9806 3179189 Maybridge4_003772 Cc1noc(c1NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L11 compound treatment 0.206 -0.0165 -0.24 0.28 0.0701 1.18 0.6643 0.5538 3065377 Maybridge4_003773 CN1N=C(CC1c2ccc(F)cc2)c3ccc4ccccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L12 compound treatment 0.228 0.00547 0.08 0.248 0.0381 0.64 0.507 0.7878 3179190 Maybridge4_003774 CC1(C)Cc2cccc(C(=O)Nc3cccc4CCCCc34)c2O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L13 compound treatment 0.28 0.0575 0.82 0.246 0.0361 0.61 1.0092 0.9887 3065378 Maybridge4_003775 Cc1ccc2n(CNc3ccc(OC(F)(F)F)cc3)nnc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L14 compound treatment 0.194 -0.0285 -0.41 0.224 0.0141 0.24 -0.1217 -0.2581 3179191 Maybridge4_003776 O=S(=O)(N(Cc1ccccn1)Cc2ccccn2)c3ccc(s3)c4ccon4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L15 compound treatment 0.252 0.0295 0.42 0.21 6.25E-5 0.0 0.2988 0.7089 3065424 Maybridge4_003777 CCOC(=O)C1(CCC#N)C(CC(=CC1=O)c2ccc(OC)cc2)c3ccc4ccccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L16 compound treatment 0.274 0.0515 0.74 0.23 0.0201 0.34 0.7587 0.9372 3065425 Maybridge4_003778 Clc1ccc(cc1)C(=O)NCc2ccc(s2)S(=O)(=O)NCCN3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L17 compound treatment 0.243 0.0205 0.29 0.221 0.0111 0.19 0.3383 0.9758 3065426 Maybridge4_003779 CN(C)/C=C/C(=S)c1cccs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L18 compound treatment 0.188 -0.0345 -0.49 0.245 0.0351 0.59 0.0669 0.087 3065427 Maybridge4_003780 CN1CCN(CC1)c2ccc(CNC(=O)c3cccnc3Oc4ccc(Cl)cc4)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L19 compound treatment 0.189 -0.0335 -0.48 0.229 0.0191 0.32 -0.1129 -0.1958 3065428 Maybridge4_003781 CSc1nnc(/N=C/c2c(O)ccc3ccccc23)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L20 compound treatment 0.288 0.0655 0.94 0.273 0.0631 1.06 1.4106 0.9981 3065429 Maybridge4_003782 OC(CSc1nc(c2ccccc2)n(n1)c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L21 compound treatment 0.297 0.0745 1.07 0.276 0.0661 1.11 1.5372 0.9998 3065430 Maybridge4_003783 Cc1ccc(Cl)cc1NC(=S)N(N)CCO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L22 compound treatment 0.232 0.00947 0.14 0.273 0.0631 1.06 0.8442 0.7911 3179192 Maybridge4_003784 FC(F)(F)c1c(cnn1c2ccccc2)C(=O)NC3CCCCNC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L23 mock treatment 0.213 -0.00953 -0.14 0.204 -0.00594 -0.1 -0.1669 -0.9881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 L24 mock treatment 0.211 -0.0115 -0.16 0.217 0.00706 0.12 -0.0328 -0.1615 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M01 compound treatment 0.279 0.0565 0.81 0.276 0.0661 1.11 1.3552 0.9879 3065431 Maybridge4_003785 Clc1cccc(c1)n2c(SCC3CC3)nnc2C4CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M02 compound treatment 0.28 0.0575 0.82 0.257 0.0471 0.79 1.1398 0.9998 3179193 Maybridge4_003786 CN(C)C(=S)NC(Cc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M03 compound treatment 0.254 0.0315 0.45 0.258 0.0481 0.81 0.8887 0.962 3179194 Maybridge4_003787 CCCc1nc(SCC(=O)c2ccccc2Cl)nc(O)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M04 compound treatment 0.226 0.00347 0.05 0.24 0.0301 0.5 0.3919 0.7729 3065433 Maybridge4_003788 CCc1ccc(NC(=O)NC(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M05 compound treatment 0.206 -0.0165 -0.24 0.219 0.00906 0.15 -0.0596 -0.2121 1572084 Maybridge4_003789 Cc1ccc(NC(=S)Nc2ccccc2C)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M06 compound treatment 0.297 0.0745 1.07 0.294 0.0841 1.41 1.7509 0.9904 1569198 Maybridge4_003790 O=C1N(Cc2ccncc2)C(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M07 compound treatment 0.254 0.0315 0.45 0.227 0.0171 0.29 0.5208 0.9762 3179195 Maybridge4_003791 C(/N=C/c1ccco1)C2CCC(C/N=C/c3ccco3)CC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M08 compound treatment 0.253 0.0305 0.44 0.258 0.0481 0.81 0.8786 0.9582 1300916 Maybridge4_003792 CCOc1ccc(NC(=S)NC(C)(C)CC)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M09 compound treatment 0.163 -0.0595 -0.85 0.136 -0.0739 -1.24 -1.4796 -0.9831 1039987 Maybridge4_003793 CC(C)N1CSC(=S)N(C1)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M10 compound treatment 0.26 0.0375 0.54 0.267 0.0571 0.96 1.0562 0.9624 1339416 Maybridge4_003794 Cc1cc(ccc1Br)n2c(=O)c3ccccc3[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M11 compound treatment 0.233 0.0105 0.15 0.199 -0.0109 -0.18 -0.0239 -0.101 3179196 Maybridge4_003795 COc1ccc(CCN2C(=O)/C(=C/c3ccccc3Cl)/SC2=S)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M12 compound treatment 0.247 0.0245 0.35 0.216 0.00606 0.1 0.3194 0.8764 3065435 Maybridge4_003796 CC(C)(C)c1ccc(cc1)C2=NC(C)(C)CO2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M13 compound treatment 0.243 0.0205 0.29 0.226 0.0161 0.27 0.3977 0.9992 3179281 Maybridge4_003797 S=C(NCCc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M14 compound treatment 0.232 0.00947 0.14 0.251 0.0411 0.69 0.5831 0.8302 3179282 Maybridge4_003798 Cc1onc(c1C(=O)OC2=CC(=O)CC(C)(C)C2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M15 compound treatment 0.201 -0.0215 -0.31 0.08 -0.13 -2.18 -1.7599 -0.799 3065437 Maybridge4_003799 CC(C)c1ccc(NC(=S)NCc2ccc(C#N)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M16 compound treatment 0.257 0.0345 0.49 0.18 -0.0299 -0.5 -0.0067 -0.0095 3179283 Maybridge4_003800 COc1ccc(cc1)C(=O)N/C(=N/c2c(C)cccc2C)/SC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M17 compound treatment 0.238 0.0155 0.22 0.266 0.0561 0.94 0.8218 0.8502 3065438 Maybridge4_003801 CSc1cccc(NC(=O)N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M18 compound treatment 0.252 0.0295 0.42 0.212 0.00206 0.03 0.3225 0.7626 3065439 Maybridge4_003802 N/C(=C(\N=C\c1ccc(C#N)cc1)/C#N)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M19 compound treatment 0.233 0.0105 0.15 0.206 -0.00394 -0.07 0.0592 0.3614 3179284 Maybridge4_003803 O=C1CSC(=S)N1/N=C/c2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M20 compound treatment 0.218 -0.00453 -0.06 0.202 -0.00794 -0.13 -0.14 -0.9452 3179285 Maybridge4_003804 CCC(C)(CC(=O)O)CC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M21 compound treatment 0.269 0.0465 0.66 0.232 0.0221 0.37 0.7318 0.9618 3065440 Maybridge4_003805 Cc1ccc(cc1)C2=NN3C(C2)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M22 compound treatment 0.23 0.00747 0.11 0.239 0.0291 0.49 0.4205 0.842 1441619 Maybridge4_003806 COc1ccc(CCN2C(SC(C)C2=O)c3cccnc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M23 mock treatment 0.222 -5.31E-4 -0.01 0.268 0.0581 0.97 0.6837 0.7016 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 M24 mock treatment 0.226 0.00347 0.05 0.232 0.0221 0.37 0.2969 0.7947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N01 compound treatment 0.216 -0.00653 -0.09 0.272 0.0621 1.04 0.6705 0.6411 3065441 Maybridge4_003807 S=C(N1CCSCC1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N02 compound treatment 0.234 0.0115 0.16 0.238 0.0281 0.47 0.449 0.9003 1195820 Maybridge4_003808 CC(C)c1ccc(cc1)C2C3CCc4ccccc4C3=NN2CCO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N03 compound treatment 0.16 -0.0625 -0.89 0.225 0.0151 0.25 -0.4537 -0.4881 3065442 Maybridge4_003809 FC(F)(F)c1cc(NC(C#N)c2ccccc2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N04 compound treatment 0.264 0.0415 0.59 0.28 0.0701 1.18 1.2509 0.9498 1398220 Maybridge4_003810 OC(=O)C(C(=O)OCc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N05 compound treatment 0.212 -0.0105 -0.15 0.219 0.00906 0.15 0.001 0.0049 3065443 Maybridge4_003811 CC1CC(=O)N(C1=O)c2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N06 compound treatment 0.209 -0.0135 -0.19 0.234 0.0241 0.4 0.1487 0.3321 1541655 Maybridge4_003812 COc1ccc(NC(=O)c2ccc3ncsc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N07 compound treatment 0.239 0.0165 0.24 0.276 0.0661 1.11 0.9506 0.8386 3065444 Maybridge4_003813 Oc1ccccc1/C=N/c2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N08 compound treatment 0.277 0.0545 0.78 0.262 0.0521 0.87 1.1688 0.9984 3179286 Maybridge4_003814 CCOC(=O)c1ccc(cc1)n2c(=S)[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N09 compound treatment 0.242 0.0195 0.28 0.261 0.0511 0.86 0.8029 0.891 3065445 Maybridge4_003815 CC(C)c1ccc2[n+](C)cccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N10 compound treatment 0.247 0.0245 0.35 0.248 0.0381 0.64 0.6992 0.9599 3064681 Maybridge4_003816 Cc1noc(c1NC(=O)N2CCOCC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N11 compound treatment 0.264 0.0415 0.59 0.215 0.00506 0.08 0.4795 0.8002 1587431 Maybridge4_003817 COc1ccc(cc1)C2CC(=NN2C)c3ccc4ccccc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N12 compound treatment 0.228 0.00547 0.08 0.25 0.0401 0.67 0.5308 0.7841 3064636 Maybridge4_003818 Fc1cc(C(=O)NCc2nc3ccccc3s2)c4OCOCc4c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N13 compound treatment 0.278 0.0555 0.79 0.268 0.0581 0.97 1.2501 0.9948 3064637 Maybridge4_003819 OC(=O)/C=C/C(=O)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N14 compound treatment 0.279 0.0565 0.81 0.286 0.0761 1.28 1.4739 0.9756 3064638 Maybridge4_003820 O=C(N(Cc1ccccn1)Cc2ccccn2)c3ccc4nsnc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N15 compound treatment 0.22 -0.00253 -0.04 0.26 0.0501 0.84 0.5685 0.676 1376553 Maybridge4_003821 CN1N=C2C(CCCc3ccccc23)C1c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N16 compound treatment 0.304 0.0815 1.17 0.314 0.104 1.75 2.059 0.9807 3064639 Maybridge4_003822 Cc1cc(CNC(=O)c2cnc3ccccc3n2)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N17 compound treatment 0.285 0.0625 0.89 0.218 0.00806 0.14 0.7275 0.805 3064640 Maybridge4_003823 COc1ccccc1CNC(=S)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N18 compound treatment 0.195 -0.0275 -0.39 0.203 -0.00694 -0.12 -0.3608 -0.8786 3179287 Maybridge4_003824 CN1CCN(CC1)c2ccc(CNC(=O)c3cnn(c3C)c4ccc(Cl)cc4)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N19 compound treatment 0.252 0.0295 0.42 0.3 0.0901 1.51 1.3669 0.8711 1418353 Maybridge4_003825 CC1=NN(C(=O)C1=C2SCCCS2)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N20 compound treatment 0.242 0.0195 0.28 0.237 0.0271 0.45 0.5181 0.9724 3064641 Maybridge4_003826 OC(CSc1nccc(n1)c2ccc3OCCOc3c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N21 compound treatment 0.241 0.0185 0.26 0.211 0.00106 0.02 0.1994 0.7531 3179288 Maybridge4_003827 COc1ccc(/N=C\2/SCC(=NN2CCO)c3ccc(C)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N22 compound treatment 0.25 0.0275 0.39 0.227 0.0171 0.29 0.4803 0.9879 3179289 Maybridge4_003828 CC(C)(Oc1ccc(Cl)cc1)C(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N23 mock treatment 0.221 -0.00153 -0.02 0.219 0.00906 0.15 0.0921 0.5991 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 N24 mock treatment 0.246 0.0235 0.34 0.179 -0.0309 -0.52 -0.1298 -0.2099 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O01 compound treatment 0.222 -5.31E-4 -0.01 0.268 0.0581 0.97 0.6837 0.7016 3064642 Maybridge4_003829 Fc1ccc(NC2=NCCCC(=O)S2)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O02 compound treatment 0.289 0.0665 0.95 0.198 -0.0119 -0.2 0.5306 0.5461 3179290 Maybridge4_003830 Cc1cc(/N=C/c2cc(Cl)cc(Cl)c2O)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O03 compound treatment 0.254 0.0315 0.45 0.232 0.0221 0.37 0.5801 0.9953 1155572 Maybridge4_003831 CC(C)(C)C(=O)COC(=O)Cn1nnc(n1)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O04 compound treatment 0.243 0.0205 0.29 0.254 0.0441 0.74 0.73 0.9177 3179291 Maybridge4_003832 CC(C)(C)NC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O05 compound treatment 0.265 0.0425 0.61 0.168 -0.0419 -0.7 -0.0682 -0.0733 1006391 Maybridge4_003833 Cc1ccc(NC(=S)Nc2ccc(C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O06 compound treatment 0.227 0.00447 0.06 0.255 0.0451 0.76 0.58 0.7641 3179292 Maybridge4_003834 COc1cccc(/C=N\c2ccccc2N3C(=O)c4ccccc4C3=O)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O07 compound treatment 0.237 0.0145 0.21 0.271 0.0611 1.02 0.871 0.8331 1631575 Maybridge4_003835 CCOc1ccc(NC(=S)NC(Cc2ccccc2)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O08 compound treatment 0.233 0.0105 0.15 0.265 0.0551 0.92 0.7594 0.8111 3179293 Maybridge4_003836 CCOC(=O)c1ccc(NC(=S)NC(C)c2ccc3OCCOc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O09 compound treatment 0.259 0.0365 0.52 0.258 0.0481 0.81 0.9393 0.9777 1028763 Maybridge4_003837 OC(=O)CSC(=S)c1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O10 compound treatment 0.225 0.00247 0.04 0.215 0.00506 0.08 0.0851 0.9243 3179294 Maybridge4_003838 N/C(=N\O)/c1c(cc([nH]c1=O)c2ccc(F)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O11 compound treatment 0.24 0.0175 0.25 0.201 -0.00894 -0.15 0.0706 0.2423 1080231 Maybridge4_003839 COc1ccc(cc1)C(CC(=O)c2ccccc2)Sc3ccccc3N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O12 compound treatment 0.187 -0.0355 -0.51 0.206 -0.00394 -0.07 -0.4061 -0.7924 1192868 Maybridge4_003840 CC(C)c1ccc(cc1)N2C(=O)SC(C2=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O13 compound treatment 0.207 -0.0155 -0.22 0.239 0.0291 0.49 0.1878 0.3504 3179295 Maybridge4_003841 CN(C)C(=O)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O14 compound treatment 0.218 -0.00453 -0.06 0.24 0.0301 0.5 0.311 0.6113 3179296 Maybridge4_003842 CC(C)(C)c1ccc(cc1)C(=O)OC2=CC(=O)CC(C)(C)C2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O15 compound treatment 0.213 -0.00953 -0.14 0.198 -0.0119 -0.2 -0.2381 -0.9824 3064643 Maybridge4_003843 C/C(=N\Cc1ccc(Cl)c(Cl)c1)/c2ccccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O16 compound treatment 0.198 -0.0245 -0.35 0.208 -0.00194 -0.03 -0.2711 -0.7693 3179297 Maybridge4_003844 CC(C)(C)NC(=S)N1CCSCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O17 compound treatment 0.072 -0.151 -2.15 0.069 -0.141 -2.37 -3.1952 -0.9989 3064645 Maybridge4_003845 CSc1cccc(NC(=S)Nc2cccc(SC)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O18 compound treatment 0.242 0.0195 0.28 0.206 -0.00394 -0.07 0.1502 0.5247 3179298 Maybridge4_003846 CN(C)/C=C/1\N=C(NC1=O)SCc2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O19 compound treatment 0.215 -0.00753 -0.11 0.206 -0.00394 -0.07 -0.1229 -0.9725 3179299 Maybridge4_003847 CCO/C=C/1\SC(=S)N(/N=C/c2cccc(Cl)c2)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O20 compound treatment 0.17 -0.0525 -0.75 0.142 -0.0679 -1.14 -1.3376 -0.9795 3064646 Maybridge4_003848 Cc1ccc(cc1)C(=O)CC(Sc2ccccc2N)c3ccsc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O21 compound treatment 0.214 -0.00853 -0.12 0.229 0.0191 0.32 0.1399 0.4087 3179300 Maybridge4_003849 Clc1ccc(Cl)c(c1)C2=NN3C(C2)c4ccccc4C3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O22 compound treatment 0.205 -0.0175 -0.25 0.248 0.0381 0.64 0.2744 0.3998 3064648 Maybridge4_003850 Cc1oc2ccccc2c1CCOC(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O23 mock treatment 0.23 0.00747 0.11 0.201 -0.00894 -0.15 -0.0305 -0.1658 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 O24 mock treatment 0.194 -0.0285 -0.41 0.186 -0.0239 -0.4 -0.5727 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P01 compound treatment 0.206 -0.0165 -0.24 0.211 0.00106 0.02 -0.1546 -0.6519 3179301 Maybridge4_003851 CC/1=NN(C(=O)\C1=N\O)c2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P02 compound treatment 0.325 0.102 1.47 0.238 0.0281 0.47 1.3694 0.8895 1673238 Maybridge4_003852 Fc1ccc2C3Sc4ccccc4C(=O)C3=C(c2c1)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P03 compound treatment 0.217 -0.00553 -0.08 0.24 0.0301 0.5 0.3008 0.589 3179302 Maybridge4_003853 Cn1nc(sc1=S)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P04 compound treatment 0.268 0.0455 0.65 0.224 0.0141 0.24 0.6268 0.9059 3179303 Maybridge4_003854 Sc1nc(c(o1)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P05 compound treatment 0.229 0.00647 0.09 0.246 0.0361 0.61 0.4934 0.8058 3064649 Maybridge4_003855 CC1=CC(=O)N(C1=O)c2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P06 compound treatment 0.24 0.0175 0.25 0.242 0.0321 0.54 0.5572 0.9391 3179304 Maybridge4_003856 FC(F)(F)C1=NCCN(C=C1)C(=O)Nc2ccc3OCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P07 compound treatment 0.099 -0.124 -1.77 0.103 -0.107 -1.79 -2.5186 -1.0 3064650 Maybridge4_003857 FC(F)(F)Oc1ccc(Nc2n[nH]c(=S)s2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P08 compound treatment 0.253 0.0305 0.44 0.238 0.0281 0.47 0.6412 0.9992 3179305 Maybridge4_003858 Clc1ccc(NC(=S)N/2CCN\C2=N/c3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P09 compound treatment 0.256 0.0335 0.48 0.242 0.0321 0.54 0.719 0.9983 1422913 Maybridge4_003859 COc1ccc2cc(ccc2c1)C(C)C(=O)Nc3cc(Cl)cc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P10 compound treatment 0.273 0.0505 0.72 0.222 0.0121 0.2 0.6536 0.8718 3064682 Maybridge4_003860 OC(=O)CC1(CC(=O)Nc2cc3ccccc3cn2)CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P11 compound treatment 0.232 0.00947 0.14 0.222 0.0121 0.2 0.2389 0.9809 1218065 Maybridge4_003861 Cc1ccc(cc1)n2c(SCC(=O)C(C)(C)C)nc3ccccc3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P12 compound treatment 0.215 -0.00753 -0.11 0.237 0.0271 0.45 0.245 0.5248 3064683 Maybridge4_003862 Fc1cc(C(=O)NCc2csc(n2)c3cccs3)c4OCOCc4c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P13 compound treatment 0.245 0.0225 0.32 0.263 0.0531 0.89 0.857 0.9051 3064684 Maybridge4_003863 Fc1ccc(CNC2=NCCS2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P14 compound treatment 0.227 0.00447 0.06 0.222 0.0121 0.2 0.1884 0.8872 3064685 Maybridge4_003864 O=C(N(Cc1ccccn1)Cc2ccccn2)c3ncoc3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P15 compound treatment 0.243 0.0205 0.29 0.22 0.0101 0.17 0.3264 0.9658 3064686 Maybridge4_003865 CC(C)(C)c1ccc(cc1)c2nc(O)nn2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P16 compound treatment 0.244 0.0215 0.31 0.22 0.0101 0.17 0.3366 0.9603 3179306 Maybridge4_003866 Fc1cc(CNC(=O)c2cnc3ccccc3n2)c4OCOCc4c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P17 compound treatment 0.212 -0.0105 -0.15 0.217 0.00706 0.12 -0.0227 -0.1184 3064687 Maybridge4_003867 COc1ccccc1Cn2nn[nH]c2=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P18 compound treatment 0.232 0.00947 0.14 0.25 0.0401 0.67 0.5712 0.8328 3179307 Maybridge4_003868 CN1CCN(CC1)c2ccc(CNC(=O)c3ccc4nsnc4c3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P19 compound treatment 0.267 0.0445 0.64 0.282 0.0721 1.21 1.305 0.955 1399162 Maybridge4_003869 OCCN1N=C2C(CCc3ccccc23)C1c4ccccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P20 compound treatment 0.242 0.0195 0.28 0.268 0.0581 0.97 0.886 0.8742 3179308 Maybridge4_003870 Cc1csc2c(SCC(O)C(F)(F)F)ncnc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P21 compound treatment 0.228 0.00547 0.08 0.199 -0.0109 -0.18 -0.0745 -0.3733 3064689 Maybridge4_003871 NN(CCO)C(=S)NCc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P22 compound treatment 0.266 0.0435 0.62 0.286 0.0761 1.28 1.3424 0.9453 3179398 Maybridge4_003872 O=C(Cc1cccc2ccccc12)NC3CCCCNC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P23 mock treatment 0.252 0.0295 0.42 0.222 0.0121 0.2 0.4412 0.9435 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2059 P24 mock treatment 0.217 -0.00553 -0.08 0.188 -0.0219 -0.37 -0.3163 -0.8399 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A01 compound treatment 0.273 0.053 0.76 0.285 0.0467 0.78 1.0905 0.9999 3179399 Maybridge4_003873 Cn1nc(cc1C(=O)NC2CCCCNC2=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A02 compound treatment 0.256 0.036 0.51 0.256 0.0177 0.3 0.5744 0.966 1395167 Maybridge4_003874 CCCC1N(CCc2sccc12)C(=S)Nc3ccc(Cl)cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A03 compound treatment 0.269 0.049 0.7 0.279 0.0407 0.68 0.9789 0.9999 3179400 Maybridge4_003875 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3ccc4OCCCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A04 compound treatment 0.048 -0.172 -2.46 0.045 -0.193 -3.24 -4.0335 -0.9907 1342707 Maybridge4_003876 CC(C)(C)C1=NN(C(=O)C1)c2nc3ccc(Cl)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A05 compound treatment 0.254 0.034 0.49 0.284 0.0457 0.77 0.8865 0.9758 3179401 Maybridge4_003877 O=C(NCc1csc(n1)c2cccs2)c3ccno3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A06 compound treatment 0.223 0.003 0.04 0.254 0.0157 0.26 0.2169 0.8115 1644100 Maybridge4_003878 COc1ccc(OC(=O)c2cnc3SCCn3c2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A07 compound treatment 0.22 0.0 0.0 0.225 -0.0133 -0.22 -0.1576 -0.7071 3179402 Maybridge4_003879 O=C(NC1CCCCNC1=O)c2ccc(nc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A08 compound treatment 0.233 0.013 0.19 0.307 0.0687 1.15 0.947 0.8106 3179403 Maybridge4_003880 CC(C)(C)S(=O)(=O)/C(=C/c1sccc1C2OCCO2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A09 compound treatment 0.219 -0.001 -0.01 0.254 0.0157 0.26 0.1764 0.6678 3064691 Maybridge4_003881 O=S(=O)(NCc1ccc(cc1)c2cccs2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A10 compound treatment 0.261 0.041 0.59 0.302 0.0637 1.07 1.1709 0.96 3179404 Maybridge4_003882 Clc1ccc(cc1)C(=O)n2cc3CSc4ccc(Cl)cc4-c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A11 compound treatment 0.295 0.075 1.07 0.262 0.0237 0.4 1.0401 0.9089 3064692 Maybridge4_003883 Cc1nn(nc1CNC(=O)CC(C)(C)C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A12 compound treatment 0.205 -0.015 -0.21 0.264 0.0257 0.43 0.1535 0.3185 3179405 Maybridge4_003884 CCOC(=O)Cn1c2CCCC(=O)c2c(cc1=O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A13 compound treatment 0.209 -0.011 -0.16 0.24 0.00172 0.03 -0.0909 -0.568 3064694 Maybridge4_003885 Cc1noc(C)c1NC(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A14 compound treatment 0.246 0.026 0.37 0.286 0.0477 0.8 0.8293 0.9391 3179406 Maybridge4_003886 CN(C)/C(=N/C(=S)c1ccc(Cl)cc1)/C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A15 compound treatment 0.23 0.01 0.14 0.27 0.0317 0.53 0.4776 0.8664 3064695 Maybridge4_003887 Cc1cc(SCc2ncon2)c(Cl)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A16 compound treatment 0.242 0.022 0.31 0.266 0.0277 0.47 0.5515 0.9819 3179407 Maybridge4_003888 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2csc(c2)S(=O)(=O)/N=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A17 compound treatment 0.17 -0.05 -0.72 0.201 -0.0373 -0.63 -0.9482 -0.9978 3064696 Maybridge4_003889 CSc1nc(/N=C/N(C)C)n(n1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A18 compound treatment 0.222 0.002 0.03 0.201 -0.0373 -0.63 -0.4222 -0.6741 3179408 Maybridge4_003890 Cc1c2C(=O)/C(=C/c3ccccc3)/Cn2c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A19 compound treatment 0.228 0.008 0.11 0.165 -0.0733 -1.23 -0.7888 -0.6386 3179409 Maybridge4_003891 FC(F)(F)c1ccccc1NC(=S)Nc2ccc(cc2)c3csnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A20 compound treatment 0.172 -0.048 -0.69 0.195 -0.0433 -0.73 -0.9991 -0.9996 3064697 Maybridge4_003892 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A21 compound treatment 0.203 -0.017 -0.24 0.23 -0.00828 -0.14 -0.2702 -0.9648 1223239 Maybridge4_003893 Clc1ccc(cc1)C2N(CCc3sccc23)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A22 compound treatment 0.203 -0.017 -0.24 0.199 -0.0393 -0.66 -0.6381 -0.9081 1594618 Maybridge4_003894 Cc1oc2c(F)c(F)c(F)c(F)c2c1c3noc(n3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A23 mock treatment 0.216 -0.004 -0.06 0.228 -0.0103 -0.17 -0.1625 -0.8937 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 A24 mock treatment 0.184 -0.036 -0.51 0.229 -0.00928 -0.16 -0.4743 -0.8816 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B01 compound treatment 0.225 0.005 0.07 0.244 0.00572 0.1 0.1184 0.9895 3179410 Maybridge4_003895 O=C(/C=C/c1ccc(s1)c2cccs2)N3CCSCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B02 compound treatment 0.209 -0.011 -0.16 0.227 -0.0113 -0.19 -0.2451 -0.9958 3064698 Maybridge4_003896 FC(F)(F)c1oc(cc1C(=O)NCc2ccco2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B03 compound treatment 0.078 -0.142 -2.03 0.087 -0.151 -2.54 -3.2316 -0.9939 1349711 Maybridge4_003897 CSc1c([nH]c2ccccc12)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B04 compound treatment 0.232 0.012 0.17 0.276 0.0377 0.63 0.569 0.8675 3179411 Maybridge4_003898 Cc1nc(sc1c2ccnn2C(=O)C(C)(C)C)c3ccc(s3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B05 compound treatment 0.269 0.049 0.7 0.292 0.0537 0.9 1.1331 0.9922 3064699 Maybridge4_003899 CCOC(=O)c1c(CS(=O)c2ccc(Cl)cc2)oc3c(F)c(F)c(F)c(F)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B06 compound treatment 0.214 -0.006 -0.09 0.239 7.19E-4 0.01 -0.0522 -0.6018 3179412 Maybridge4_003900 C/C(=N\O)/C(=O)c1ccc(cc1)c2ccccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B07 compound treatment 0.263 0.043 0.62 0.278 0.0397 0.67 0.9063 0.9992 3179413 Maybridge4_003901 CC1(C)COC(=N1)c2sccc2C(=O)N(C3CCCCC3)C(=O)NC4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B08 compound treatment 0.305 0.085 1.22 0.281 0.0427 0.72 1.3667 0.9683 3064701 Maybridge4_003902 Nc1ccccc1SCc2cccc(Cl)c2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B09 compound treatment 0.308 0.088 1.26 0.279 0.0407 0.68 1.3733 0.9588 1459519 Maybridge4_003903 NC(=S)c1cnc(nc1N)c2ccncc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B10 compound treatment 0.228 0.008 0.11 0.287 0.0487 0.82 0.6591 0.7983 1481845 Maybridge4_003904 CCCNC(=S)N1CCC(CC1)C(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B11 compound treatment 0.311 0.091 1.3 0.337 0.0987 1.66 2.092 0.9929 3064731 Maybridge4_003905 NC(=S)c1ncc(cc1N2CCCC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B12 compound treatment 0.235 0.015 0.21 0.275 0.0367 0.62 0.5875 0.9003 3064732 Maybridge4_003906 Cc1noc(C)c1c2nc(no2)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B13 compound treatment 0.232 0.012 0.17 0.296 0.0577 0.97 0.8064 0.8196 3064733 Maybridge4_003907 COc1cc(NC(=O)C(C)(C)C)ccc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B14 compound treatment 0.272 0.052 0.74 0.277 0.0387 0.65 0.9855 0.9977 3064734 Maybridge4_003908 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(NC(=O)c4ccco4)cn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B15 compound treatment 0.23 0.01 0.14 0.298 0.0597 1.0 0.8099 0.7999 3064735 Maybridge4_003909 CN(N1C(=O)c2ccccc2C1=O)c3cc(ccn3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B16 compound treatment 0.26 0.04 0.57 0.276 0.0377 0.63 0.8522 0.9987 1391890 Maybridge4_003910 CC(C)(C)c1cc(n(n1)c2ccc(NC(=O)COCC(=O)O)cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B17 compound treatment 0.228 0.008 0.11 0.274 0.0357 0.6 0.5048 0.8271 3179414 Maybridge4_003911 Cc1cc(C)n(n1)c2ccc(cc2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B18 compound treatment 0.26 0.04 0.57 0.22 -0.0183 -0.31 0.1876 0.289 1368065 Maybridge4_003912 CC(C)Cc1ccc(cc1)C(C)c2nc(no2)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B19 compound treatment 0.279 0.059 0.84 0.251 0.0127 0.21 0.7477 0.8589 1510531 Maybridge4_003913 COc1cc(cc(OC)c1OC)C(=O)NCC(c2c[nH]c3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B20 compound treatment 0.305 0.085 1.22 0.315 0.0767 1.29 1.7702 0.9996 1512133 Maybridge4_003914 COc1ccc(cc1)C2N(CCc3sccc23)C(=O)NC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B21 compound treatment 0.318 0.098 1.4 0.293 0.0547 0.92 1.6406 0.979 3064736 Maybridge4_003915 Cc1snnc1C(=O)Oc2ccccc2c3nnco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B22 compound treatment 0.239 0.019 0.27 0.315 0.0767 1.29 1.1027 0.8379 3179415 Maybridge4_003916 CC(C)(C)c1cc(n(n1)c2ccc(/N=C\c3ccccc3O)cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B23 mock treatment 0.226 0.006 0.09 0.265 0.0267 0.45 0.3778 0.8274 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 B24 mock treatment 0.198 -0.022 -0.31 0.239 7.19E-4 0.01 -0.214 -0.6795 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C01 compound treatment 0.257 0.037 0.53 0.269 0.0307 0.52 0.7388 0.9999 3064737 Maybridge4_003917 Clc1ccc(Oc2ncccc2C(=O)NC3CCCCNC3=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C02 compound treatment 0.25 0.03 0.43 0.279 0.0407 0.68 0.7867 0.9749 1245123 Maybridge4_003918 O=C(NCc1ccco1)NC(=O)c2ccc(cc2)c3csnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C03 compound treatment 0.274 0.054 0.77 0.324 0.0857 1.44 1.5635 0.9575 3064739 Maybridge4_003919 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3c(C)nn(C)c3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C04 compound treatment 0.265 0.045 0.64 0.279 0.0407 0.68 0.9384 0.9996 3179416 Maybridge4_003920 CC(C)(C)c1csc(Cc2ccc(cc2)c3csnn3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C05 compound treatment 0.283 0.063 0.9 0.322 0.0837 1.41 1.6308 0.9769 3179417 Maybridge4_003921 Cc1oc(cc1C(=O)NCc2csc(n2)c3cccs3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C06 compound treatment 0.3 0.08 1.14 0.292 0.0537 0.9 1.4467 0.993 1605864 Maybridge4_003922 OC(=O)CCCc1nc(no1)c2cnc3SCCn3c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C07 compound treatment 0.257 0.037 0.53 0.276 0.0377 0.63 0.8219 0.996 3179418 Maybridge4_003923 O=C(NCC1CN(Cc2ccccc2)CCO1)c3ccc(nc3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C08 compound treatment 0.266 0.046 0.66 0.285 0.0467 0.78 1.0197 0.9962 3064740 Maybridge4_003924 COC(=O)c1cc2CSc3ccc(Cl)cc3-c2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C09 compound treatment 0.269 0.049 0.7 0.266 0.0277 0.47 0.8246 0.9802 3179419 Maybridge4_003925 O=C(NCc1ccc(cc1)c2cccs2)C3=Cc4ccccc4OC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C10 compound treatment 0.252 0.032 0.46 0.298 0.0597 1.0 1.0324 0.9369 3064741 Maybridge4_003926 CC(C)(C)C(=O)n1cc2CSc3ccc(Cl)cc3-c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C11 compound treatment 0.288 0.068 0.97 0.284 0.0457 0.77 1.2304 0.9931 3179420 Maybridge4_003927 COCC(=O)NCc1nn(nc1C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C12 compound treatment 0.25 0.03 0.43 0.281 0.0427 0.72 0.8104 0.9699 3064742 Maybridge4_003928 COC(=O)c1sccc1c2ccc(o2)c3ccn(n3)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C13 compound treatment 0.263 0.043 0.62 0.3 0.0617 1.04 1.1674 0.969 3179421 Maybridge4_003929 Cc1cc(CNC(=O)Nc2c(C)noc2C)c(o1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C14 compound treatment 0.314 0.094 1.34 0.33 0.0917 1.54 2.0393 0.9977 3064743 Maybridge4_003930 Clc1ccc(NC(=O)/C(=C\c2cccs2)/c3ccsc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C15 compound treatment 0.247 0.027 0.39 0.29 0.0517 0.87 0.8869 0.9335 3179422 Maybridge4_003931 CN(C)C(=O)Oc1cccc(N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C16 compound treatment 0.282 0.062 0.89 0.226 -0.0123 -0.21 0.4813 0.5287 3179423 Maybridge4_003932 FC(F)(F)Oc1ccccc1/C=N/c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C17 compound treatment 0.261 0.041 0.59 0.232 -0.00628 -0.11 0.3401 0.5708 1299325 Maybridge4_003933 CC(C)N(C(C)C)C(=O)NC(=O)c1csnn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C18 compound treatment 0.269 0.049 0.7 0.258 0.0197 0.33 0.7296 0.9413 3179518 Maybridge4_003934 FC(F)(F)C1NCCc2c1[nH]c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C19 compound treatment 0.255 0.035 0.5 0.262 0.0237 0.4 0.6355 0.9936 1154654 Maybridge4_003935 Cc1noc(C)c1c2nc(CSc3ccccc3)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C20 compound treatment 0.232 0.012 0.17 0.285 0.0467 0.78 0.6758 0.842 3179519 Maybridge4_003936 O=C(NCc1ccc(s1)c2cccs2)NC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C21 compound treatment 0.235 0.015 0.21 0.299 0.0607 1.02 0.8723 0.8376 1179307 Maybridge4_003937 CC(C)NC(=O)N1CCc2sccc2C1c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C22 compound treatment 0.137 -0.083 -1.19 0.21 -0.0283 -0.47 -1.1751 -0.9191 3064744 Maybridge4_003938 CC(C)(C)c1nc(no1)c2ccc(s2)c3ccon3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C23 mock treatment 0.224 0.004 0.06 0.238 -2.81E-4 0.0 0.0371 0.6466 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 C24 mock treatment 0.189 -0.031 -0.44 0.211 -0.0273 -0.46 -0.6373 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D01 compound treatment 0.229 0.009 0.13 0.253 0.0147 0.25 0.2657 0.9538 3179520 Maybridge4_003939 CC(C)(C)c1ccc(NC(=O)/C=C/c2ccc(s2)c3cccs3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D02 compound treatment 0.221 0.001 0.01 0.279 0.0407 0.68 0.4934 0.7217 3064745 Maybridge4_003940 COc1cccc(/C=N/c2c(c(nn2C)C(F)(F)F)c3ccccc3)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D03 compound treatment 0.236 0.016 0.23 0.3 0.0617 1.04 0.8943 0.843 1138512 Maybridge4_003941 COc1ccc(cc1)S(=O)(=O)CC(C)(O)CS(=O)(=O)c2ccc(OC)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D04 compound treatment 0.255 0.035 0.5 0.28 0.0417 0.7 0.8491 0.9865 3064746 Maybridge4_003942 FC(F)(F)c1ccc(/C=N/c2cc(Cl)cc(Cl)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D05 compound treatment 0.282 0.062 0.89 0.288 0.0497 0.83 1.2171 0.9995 3179521 Maybridge4_003943 Cc1noc(C)c1c2nc(COc3ccc(/C=C(/C#N)\S(=O)(=O)C)cc3)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D06 compound treatment 0.362 0.142 2.03 0.253 0.0147 0.25 1.6109 0.7873 3064747 Maybridge4_003944 CCc1sc(nc1C(=O)OC)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D07 compound treatment 0.272 0.052 0.74 0.319 0.0807 1.35 1.4839 0.9601 3064748 Maybridge4_003945 Cc1ccsc1C(=S)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D08 compound treatment 0.247 0.027 0.39 0.331 0.0927 1.56 1.3735 0.8566 3179522 Maybridge4_003946 FC(F)(F)c1cc(Oc2ccc(cc2)n3cccc3)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D09 compound treatment 0.347 0.127 1.82 0.342 0.104 1.74 2.5155 0.9998 3064749 Maybridge4_003947 CSc1ccc(s1)C(=O)NC(=O)Nc2cc(C)on2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D10 compound treatment 0.308 0.088 1.26 0.303 0.0647 1.09 1.6581 0.9973 3179523 Maybridge4_003948 CS/C(=N\C#N)/N1CCC(CC1)C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D11 compound treatment 0.23 0.01 0.14 0.252 0.0137 0.23 0.264 0.9738 1573241 Maybridge4_003949 Cc1noc(C)c1C(=O)Oc2ccc(cc2)c3nn[nH]c3C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D12 compound treatment 0.337 0.117 1.67 0.28 0.0417 0.7 1.6785 0.9252 3064792 Maybridge4_003950 CC(C)(C)NC(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D13 compound treatment 0.342 0.122 1.75 0.262 0.0237 0.4 1.5154 0.8467 3064793 Maybridge4_003951 CCOC(=O)c1cc(CSc2ccc(Cl)cc2)c3OCOCc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D14 compound treatment 0.316 0.096 1.37 0.292 0.0537 0.9 1.6085 0.9792 3064794 Maybridge4_003952 COc1ccccc1N2CCN(CC2)C(=S)c3ccccc3OC(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D15 compound treatment 0.249 0.029 0.41 0.255 0.0167 0.28 0.4917 0.9819 3064795 Maybridge4_003953 CN(N1C(=O)CSCC1=O)c2cc(ccn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D16 compound treatment 0.293 0.073 1.04 0.261 0.0227 0.38 1.008 0.9068 3064796 Maybridge4_003954 N/C(=N\O)/c1ccc(nc1)N2CCN(CC2)c3ncccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D17 compound treatment 0.284 0.064 0.92 0.294 0.0557 0.94 1.3086 0.9999 3064797 Maybridge4_003955 Cc1nn(c(C)c1C(=O)Oc2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D18 compound treatment 0.046 -0.174 -2.49 0.054 -0.184 -3.09 -3.9469 -0.9942 3064798 Maybridge4_003956 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)Oc2cccc3cccnc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D19 compound treatment 0.224 0.004 0.06 0.201 -0.0373 -0.63 -0.402 -0.6398 3064800 Maybridge4_003957 FC(F)(F)c1ccc(cc1)C(=O)NCC(c2c[nH]c3ccccc23)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D20 compound treatment 0.252 0.032 0.46 0.248 0.00972 0.16 0.439 0.9034 3179524 Maybridge4_003958 FC(F)(F)c1cccnc1N2CCN(CC2)c3ccc(NC(=O)Nc4ccc(Cl)cc4)cn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D21 compound treatment 0.225 0.005 0.07 0.286 0.0477 0.8 0.6169 0.7672 3064801 Maybridge4_003959 CN(C)/C=C(\C#N)/c1nnc(c2ccccn2)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D22 compound treatment 0.234 0.014 0.2 0.3 0.0617 1.04 0.8741 0.8285 3179525 Maybridge4_003960 Fc1ccc(CS(=O)(=O)CCNC(=O)c2c(F)cccc2Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D23 mock treatment 0.281 0.061 0.87 0.292 0.0537 0.9 1.2545 0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 D24 mock treatment 0.228 0.008 0.11 0.229 -0.00928 -0.16 -0.0292 -0.1513 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E01 compound treatment 0.266 0.046 0.66 0.221 -0.0173 -0.29 0.2602 0.3618 3179526 Maybridge4_003961 O=C(NC1CCCCNC1=O)c2cn(c3ccccc23)S(=O)(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E02 compound treatment 0.311 0.091 1.3 0.263 0.0247 0.41 1.2138 0.8884 3064802 Maybridge4_003962 FC(F)(F)c1ccc(cc1)C2=NCCc3sccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E03 compound treatment 0.285 0.065 0.93 0.316 0.0777 1.3 1.5798 0.9862 3179527 Maybridge4_003963 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3ccc4OC(C)(C)CCc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E04 compound treatment 0.237 0.017 0.24 0.287 0.0487 0.82 0.7501 0.8793 3064804 Maybridge4_003964 O=C(Nc1ccccc1)Nc2cccc(c2)c3nnco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E05 compound treatment 0.255 0.035 0.5 0.29 0.0517 0.87 0.9678 0.9658 3064805 Maybridge4_003965 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccno2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E06 compound treatment 0.203 -0.017 -0.24 0.087 -0.151 -2.54 -1.9674 -0.7713 1736114 Maybridge4_003966 COc1ccc(cc1)C2N(CCc3sccc23)C(=S)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E07 compound treatment 0.293 0.073 1.04 0.299 0.0607 1.02 1.459 0.9999 3179528 Maybridge4_003967 Cc1nn(C)c(C)c1CNC(=O)c2ccc(nc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E08 compound treatment 0.329 0.109 1.56 0.253 0.0147 0.25 1.2771 0.8091 3064806 Maybridge4_003968 O=C(NC(=O)c1nnc(o1)c2ccccc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E09 compound treatment 0.305 0.085 1.22 0.295 0.0567 0.95 1.5329 0.9927 3179529 Maybridge4_003969 COc1ccc(cc1)n2ncc(C(=O)NCc3ccc(cc3)c4cccs4)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E10 compound treatment 0.33 0.11 1.57 0.322 0.0837 1.41 2.1061 0.9984 3064807 Maybridge4_003970 CC(C)c1ncc2CSc3ccc(Cl)cc3-c2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E11 compound treatment 0.281 0.061 0.87 0.318 0.0797 1.34 1.5631 0.9785 3179530 Maybridge4_003971 COc1ccc(cc1)c2ocnc2C(=O)NCc3nn(nc3C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E12 compound treatment 0.308 0.088 1.26 0.283 0.0447 0.75 1.4208 0.9695 3064809 Maybridge4_003972 COC(=O)c1sccc1c2ccc(o2)c3ccn(n3)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E13 compound treatment 0.301 0.081 1.16 0.27 0.0317 0.53 1.1957 0.9378 3179531 Maybridge4_003973 Cc1c(C)c(C)c2[nH]c(nc2c1C)c3ccc4OCOc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E14 compound treatment 0.228 0.008 0.11 0.222 -0.0163 -0.27 -0.1123 -0.3791 3179532 Maybridge4_003974 FC(F)(F)c1cccc(NC(=O)/C(=C\c2cccs2)/c3ccsc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E15 compound treatment 0.265 0.045 0.64 0.308 0.0697 1.17 1.2826 0.9604 3064810 Maybridge4_003975 FC(F)(F)c1ccccc1N/C(=N/C#N)/N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E16 compound treatment 0.247 0.027 0.39 0.247 0.00872 0.15 0.3766 0.9118 3179533 Maybridge4_003976 FC(F)(F)c1cccc(NC(=O)CS(=O)(=O)Nc2cccc(c2)C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E17 compound treatment 0.294 0.074 1.06 0.284 0.0457 0.77 1.291 0.9875 3064811 Maybridge4_003977 Cc1cc(NC(=O)NC(=O)c2csnn2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E18 compound treatment 0.119 -0.101 -1.44 0.14 -0.0983 -1.65 -2.1879 -0.9978 3179534 Maybridge4_003978 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E19 compound treatment 0.198 -0.022 -0.31 0.272 0.0337 0.57 0.1777 0.2744 3064812 Maybridge4_003979 Cc1noc(C)c1c2nc(CS(=O)(=O)Cc3ccc(Cl)cc3)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E20 compound treatment 0.245 0.025 0.36 0.291 0.0527 0.88 0.8785 0.9205 3064813 Maybridge4_003980 Cc1cc(cc(C)c1I)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E21 compound treatment 0.168 -0.052 -0.74 0.148 -0.0903 -1.52 -1.5974 -0.9463 1590769 Maybridge4_003981 CNC(=S)N1CCc2sccc2C1c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E22 compound treatment 0.246 0.026 0.37 0.27 0.0317 0.53 0.6394 0.9846 3064814 Maybridge4_003982 CN(C)/C=N/C(=O)c1ccc(s1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E23 mock treatment 0.221 0.001 0.01 0.295 0.0567 0.95 0.6833 0.7177 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 E24 mock treatment 0.219 -0.001 -0.01 0.251 0.0127 0.21 0.1408 0.6583 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F01 compound treatment 0.262 0.042 0.6 0.262 0.0237 0.4 0.7063 0.98 3179535 Maybridge4_003983 Clc1ccc(OC(=O)/C=C/c2ccc(s2)c3cccs3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F02 compound treatment 0.312 0.092 1.32 0.258 0.0197 0.33 1.1645 0.8582 3064815 Maybridge4_003984 Cc1ccc(C)n1c2ccc(cc2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F03 compound treatment 0.252 0.032 0.46 0.267 0.0287 0.48 0.6645 0.9997 1608279 Maybridge4_003985 CC(O)(CNCc1ccc(Cl)cc1)CSc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F04 compound treatment 0.235 0.015 0.21 0.272 0.0337 0.57 0.5519 0.9119 3179536 Maybridge4_003986 COC(=O)c1cc(=O)c2cc(NC(=O)c3ccc(OC(F)(F)F)cc3)ccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F05 compound treatment 0.32 0.1 1.43 0.306 0.0677 1.14 1.8151 0.9935 3064655 Maybridge4_003987 CC1(C)COC(=N1)c2sccc2C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F06 compound treatment 0.299 0.079 1.13 0.308 0.0697 1.17 1.6265 0.9998 1318553 Maybridge4_003988 NNC(=O)c1ccc(cc1)c2ccccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F07 compound treatment 0.335 0.115 1.64 0.281 0.0427 0.72 1.6701 0.9307 3179537 Maybridge4_003989 OC1CS(=O)(=O)CC1S(=O)(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F08 compound treatment 0.365 0.145 2.07 0.311 0.0727 1.22 2.3296 0.968 3064656 Maybridge4_003990 COc1cc(cc(c1C(=O)NCc2cccs2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F09 compound treatment 0.268 0.048 0.69 0.269 0.0307 0.52 0.8501 0.99 3179538 Maybridge4_003991 CSc1ccc(s1)C(=O)NC(=O)NCc2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F10 compound treatment 0.279 0.059 0.84 0.268 0.0297 0.5 0.9494 0.9685 1598180 Maybridge4_003992 CN(C)c1cnn(c2cnc3ccccc3n2)c(=O)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F11 compound treatment 0.255 0.035 0.5 0.233 -0.00528 -0.09 0.2913 0.573 3179539 Maybridge4_003993 Cc1nnsc1C(=O)Oc2ccc(cc2)c3nn[nH]c3C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F12 compound treatment 0.331 0.111 1.59 0.264 0.0257 0.43 1.4279 0.8679 3179540 Maybridge4_003994 CC(C)(C)c1cc(n(n1)c2ccc(cc2)n3cccc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F13 compound treatment 0.292 0.072 1.03 0.251 0.0127 0.21 0.8792 0.8359 3064661 Maybridge4_003995 CCOC(=O)c1cc(CSc2ccc(cn2)C(F)(F)F)c3OCOCc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F14 compound treatment 0.254 0.034 0.49 0.232 -0.00628 -0.11 0.2693 0.5413 1225795 Maybridge4_003996 CNC(=S)N1CCN(CC1)c2ccccc2OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F15 compound treatment 0.269 0.049 0.7 0.277 0.0387 0.65 0.9551 0.9993 3179541 Maybridge4_003997 Clc1cc(Cl)cc(c1)C(=O)OCCSc2cnc3ccccc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F16 compound treatment 0.33 0.11 1.57 0.276 0.0377 0.63 1.5602 0.9199 3064703 Maybridge4_003998 CS(=O)(=O)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F17 compound treatment 0.331 0.111 1.59 0.321 0.0827 1.39 2.1044 0.9978 3179628 Maybridge4_003999 FC(F)(F)c1cccc(NC(=S)N2CCCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F18 compound treatment 0.309 0.089 1.27 0.283 0.0447 0.75 1.4309 0.9682 1219010 Maybridge4_004000 COc1cccc(Oc2ccc(OC)cc2C(=O)NN)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F19 compound treatment 0.336 0.116 1.66 0.28 0.0417 0.7 1.6684 0.9264 1054347 Maybridge4_004001 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F20 compound treatment 0.256 0.036 0.51 0.213 -0.0253 -0.42 0.0641 0.096 1252794 Maybridge4_004002 CC(C)Cc1ccc(cc1)C(C)c2nc(no2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F21 compound treatment 0.216 -0.004 -0.06 0.227 -0.0113 -0.19 -0.1743 -0.8814 3179629 Maybridge4_004003 Cc1nc(sc1C(=O)Nc2ccc(Cl)cc2)C(=O)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F22 compound treatment 0.222 0.002 0.03 0.283 0.0447 0.75 0.551 0.7335 3179630 Maybridge4_004004 CC(C)(C)c1n[nH]c(c1Cc2c(F)cccc2Cl)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F23 mock treatment 0.195 -0.025 -0.36 0.243 0.00472 0.08 -0.1969 -0.5375 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 F24 mock treatment 0.211 -0.009 -0.13 0.221 -0.0173 -0.29 -0.2961 -0.9332 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G01 compound treatment 0.222 0.002 0.03 0.317 0.0787 1.32 0.9545 0.7222 3064707 Maybridge4_004005 O=C(NC1CCCCNC1=O)c2ccc3nsnc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G02 compound treatment 0.26 0.04 0.57 0.247 0.00872 0.15 0.508 0.8603 3179631 Maybridge4_004006 Cc1noc(C)c1C(=O)N2CCc3sccc3C2c4ccc(cc4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G03 compound treatment 0.283 0.063 0.9 0.273 0.0347 0.58 1.0492 0.9777 1266306 Maybridge4_004007 NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G04 compound treatment 0.265 0.045 0.64 0.31 0.0717 1.2 1.3063 0.957 3179632 Maybridge4_004008 CCOC(=O)c1ncoc1c2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G05 compound treatment 0.281 0.061 0.87 0.263 0.0247 0.41 0.9103 0.9422 3064708 Maybridge4_004009 Clc1cccc(NC(=O)NCc2csc(n2)c3cccs3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G06 compound treatment 0.291 0.071 1.02 0.294 0.0557 0.94 1.3794 0.9992 1361028 Maybridge4_004010 COc1ccc(cc1)C2N(CCc3sccc23)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G07 compound treatment 0.27 0.05 0.72 0.3 0.0617 1.04 1.2382 0.9836 3179633 Maybridge4_004011 O=C(N1CCC2(CC1)NC(=O)c3ccccc3O2)c4ncoc4c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G08 compound treatment 0.199 -0.021 -0.3 0.199 -0.0393 -0.66 -0.6786 -0.9366 3064709 Maybridge4_004012 NC(=S)c1sccc1CS(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G09 compound treatment 0.269 0.049 0.7 0.279 0.0407 0.68 0.9789 0.9999 3179634 Maybridge4_004013 COc1ccccc1CC(=O)NCc2ccc(cc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G10 compound treatment 0.313 0.093 1.33 0.268 0.0297 0.5 1.2933 0.9104 3064710 Maybridge4_004014 FC(F)(F)c1cc(=O)[nH]c2CCCC(=O)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G11 compound treatment 0.233 0.013 0.19 0.303 0.0647 1.09 0.8996 0.8163 3179635 Maybridge4_004015 Cc1nn(nc1CNC(=O)C2CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G12 compound treatment 0.234 0.014 0.2 0.252 0.0137 0.23 0.3044 0.9976 3064711 Maybridge4_004016 FC(F)(F)c1cccc(OCc2ccc(cc2)c3ncns3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G13 compound treatment 0.297 0.077 1.1 0.224 -0.0143 -0.24 0.6093 0.5406 3179636 Maybridge4_004017 Fc1cc(C(=O)NCc2ccco2)c3OCOCc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G14 compound treatment 0.295 0.075 1.07 0.314 0.0757 1.27 1.6572 0.9964 3064712 Maybridge4_004018 Fc1ccc(OC(=O)/C(=C\c2cccs2)/c3ccsc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G15 compound treatment 0.25 0.03 0.43 0.232 -0.00628 -0.11 0.2289 0.518 3179637 Maybridge4_004019 COC(=O)C1=NN(C(=O)C1)c2c(C)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G16 compound treatment 0.219 -0.001 -0.01 0.224 -0.0143 -0.24 -0.1796 -0.748 1285053 Maybridge4_004020 Fc1ccc(NC(=O)CS(=O)(=O)Nc2ccc(F)cc2Cl)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G17 compound treatment 0.299 0.079 1.13 0.298 0.0597 1.0 1.5078 0.9982 3179638 Maybridge4_004021 Clc1ccc(CSCc2ccc(cc2)c3csnn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G18 compound treatment 0.216 -0.004 -0.06 0.23 -0.00828 -0.14 -0.1387 -0.923 1173952 Maybridge4_004022 COc1cc(NS(=O)(=O)c2c(C)oc3c(F)c(F)c(F)c(F)c23)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G19 compound treatment 0.241 0.021 0.3 0.235 -0.00328 -0.06 0.1735 0.568 1587917 Maybridge4_004023 Clc1cc(Cl)cc(c1)C(=O)NCc2ccc(cc2)c3csnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G20 compound treatment 0.253 0.033 0.47 0.199 -0.0393 -0.66 -0.1324 -0.1633 3179639 Maybridge4_004024 Clc1ccc(/C=N/Cc2ccc(s2)c3cccs3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G21 compound treatment 0.254 0.034 0.49 0.224 -0.0143 -0.24 0.1744 0.3216 3064752 Maybridge4_004025 Cc1cc(C(=O)O)c(C)n1c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G22 compound treatment 0.22 0.0 0.0 0.261 0.0227 0.38 0.2696 0.7071 1446641 Maybridge4_004026 COc1ccc2ncc3COc4ccc(Cl)cc4-c3c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G23 mock treatment 0.192 -0.028 -0.4 0.26 0.0217 0.36 -0.0254 -0.047 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 G24 mock treatment 0.207 -0.013 -0.19 0.198 -0.0403 -0.68 -0.6095 -0.8693 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H01 compound treatment 0.249 0.029 0.41 0.242 0.00372 0.06 0.3374 0.8044 3064753 Maybridge4_004027 CC(=O)Nc1ccccc1OCC(O)CS(=O)(=O)c2ccc(cn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H02 compound treatment 0.274 0.054 0.77 0.284 0.0457 0.77 1.0888 1.0 3064754 Maybridge4_004028 CC(C)c1ccc(C)c2c(C#N)cc(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H03 compound treatment 0.261 0.041 0.59 0.292 0.0537 0.9 1.0522 0.9783 3064755 Maybridge4_004029 Cc1noc(c1c2nnc(o2)c3cccc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H04 compound treatment 0.269 0.049 0.7 0.279 0.0407 0.68 0.9789 0.9999 3064756 Maybridge4_004030 COc1ccc(C/N=C/c2ccc(OC)c(OC)c2)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H05 compound treatment 0.289 0.069 0.99 0.283 0.0447 0.75 1.2286 0.9909 3064758 Maybridge4_004031 Clc1ccc(cc1)c2cc[nH]n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H06 compound treatment 0.328 0.108 1.54 0.312 0.0737 1.24 1.9672 0.9939 3179640 Maybridge4_004032 COC(=O)Cc1nc(sc1C)c2ccc(F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H07 compound treatment 0.303 0.083 1.19 0.271 0.0327 0.55 1.2278 0.9386 1266051 Maybridge4_004033 COc1ccc(cc1)S(=O)(=O)C2CS(=O)(=O)CC2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H08 compound treatment 0.273 0.053 0.76 0.256 0.0177 0.3 0.7463 0.9165 3179641 Maybridge4_004034 COc1cc(cc(c1C(=O)N2CCC(CC2)C(=O)c3ccc(Cl)cc3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H09 compound treatment 0.325 0.105 1.5 0.256 0.0177 0.3 1.2723 0.831 1103147 Maybridge4_004035 N#Cc1c(nc2SCCn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H10 compound treatment 0.29 0.07 1.0 0.257 0.0187 0.31 0.9302 0.8864 3179642 Maybridge4_004036 Brc1cc(Br)cc(c1)C(=O)NC(=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H11 compound treatment 0.332 0.112 1.6 0.299 0.0607 1.02 1.8534 0.9762 3064759 Maybridge4_004037 O=S(=O)(/C(=C/c1ccc(s1)C2=CCOc3ccccc23)/C#N)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H12 compound treatment 0.336 0.116 1.66 0.266 0.0277 0.47 1.5022 0.8718 1625813 Maybridge4_004038 CCN(CC)c1ccc(NC(=O)c2ccc(Cl)cc2)c(n1)N(CC)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H13 compound treatment 0.288 0.068 0.97 0.198 -0.0403 -0.68 0.2097 0.177 3179643 Maybridge4_004039 CCOC(=O)c1cc(CSc2cccc(c2)C(F)(F)F)c3OCOCc3c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H14 compound treatment 0.272 0.052 0.74 0.288 0.0497 0.83 1.116 0.9984 3064760 Maybridge4_004040 Cc1ccc(SCCC(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H15 compound treatment 0.265 0.045 0.64 0.249 0.0107 0.18 0.5824 0.8713 1714044 Maybridge4_004041 O=C1CC(Sc2ccccc2N1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H16 compound treatment 0.235 0.015 0.21 0.292 0.0537 0.9 0.7893 0.8516 3179644 Maybridge4_004042 CNC(=S)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H17 compound treatment 0.343 0.123 1.76 0.281 0.0427 0.72 1.751 0.9217 3064761 Maybridge4_004043 FC(F)(F)c1ccccc1NC(=S)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H18 compound treatment 0.223 0.003 0.04 0.269 0.0307 0.52 0.3949 0.7633 3179645 Maybridge4_004044 Cc1ccc(SCc2cccc(c2)C(=O)N3CCN(CC3)c4ncccc4C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H19 compound treatment 0.261 0.041 0.59 0.243 0.00472 0.08 0.4707 0.7954 3064762 Maybridge4_004045 FC(F)(F)C(CNC(=O)Nc1ccccc1)c2ccc[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H20 compound treatment 0.214 -0.006 -0.09 0.202 -0.0363 -0.61 -0.4913 -0.7989 3179646 Maybridge4_004046 FC(F)(F)Oc1ccc(cc1)C2N(CCc3sccc23)C(=O)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H21 compound treatment 0.304 0.084 1.2 0.258 0.0197 0.33 1.0836 0.8695 1471144 Maybridge4_004047 Cc1nc(sc1C(=O)Oc2ccc(Cl)cc2)C(=O)Oc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H22 compound treatment 0.262 0.042 0.6 0.223 -0.0153 -0.26 0.2434 0.3727 3179647 Maybridge4_004048 CC(C)(C)C(=O)C(Cc1c(F)cccc1Cl)C(=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H23 mock treatment 0.21 -0.01 -0.14 0.295 0.0567 0.95 0.572 0.5942 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 H24 mock treatment 0.218 -0.002 -0.03 0.259 0.0207 0.35 0.2257 0.6468 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I01 compound treatment 0.252 0.032 0.46 0.217 -0.0213 -0.36 0.0711 0.1224 3064764 Maybridge4_004049 Cc1nn(C)c2sc(cc12)C(=O)NC3CCCCNC3=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I02 compound treatment 0.219 -0.001 -0.01 0.193 -0.0453 -0.76 -0.5475 -0.7203 3179648 Maybridge4_004050 FC(F)(F)c1ccc(cc1)C2N(CCc3sccc23)C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I03 compound treatment 0.254 0.034 0.49 0.255 0.0167 0.28 0.5423 0.9659 3179649 Maybridge4_004051 CC1(C)CCc2cc(ccc2O1)S(=O)(=O)NCc3ccc(cc3)S(=O)(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I04 compound treatment 0.299 0.079 1.13 0.323 0.0847 1.42 1.8045 0.9935 3064766 Maybridge4_004052 NNC(=O)c1ncoc1c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I05 compound treatment 0.329 0.109 1.56 0.294 0.0557 0.94 1.7637 0.9701 3064767 Maybridge4_004053 Cc1cc(C)cc(NC(=O)NCc2csc(n2)c3cccs3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I06 compound treatment 0.283 0.063 0.9 0.248 0.00972 0.16 0.7525 0.8218 1598083 Maybridge4_004054 NNC(=O)CS(=O)(=O)Cc1ccc(cc1)c2csnn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I07 compound treatment 0.326 0.106 1.52 0.249 0.0107 0.18 1.1993 0.7855 3179650 Maybridge4_004055 O=C(NCc1ccc2OCCc2c1)c3ccc4nsnc4c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I08 compound treatment 0.31 0.09 1.29 0.207 -0.0313 -0.53 0.539 0.3877 1651781 Maybridge4_004056 CC(C)(C)c1csc(n1)c2sccc2COc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I09 compound treatment 0.298 0.078 1.12 0.209 -0.0293 -0.49 0.4414 0.3621 3179651 Maybridge4_004057 Cn1nc(cc1C(=O)NCc2ccc(cc2)c3cccs3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I10 compound treatment 0.31 0.09 1.29 0.217 -0.0213 -0.36 0.6577 0.4923 1154669 Maybridge4_004058 Cc1nn(cc1c2nsc(Nc3ccccc3)n2)C(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I11 compound treatment 0.27 0.05 0.72 0.249 0.0107 0.18 0.6329 0.8582 3179736 Maybridge4_004059 CN1CCOc2cc(ccc12)S(=O)(=O)NCc3nn(nc3C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I12 compound treatment 0.25 0.03 0.43 0.289 0.0507 0.85 0.9054 0.9497 3064768 Maybridge4_004060 Fc1ccc(NC(=O)NC(=O)c2csc(n2)c3ccc(cc3Cl)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I13 compound treatment 0.281 0.061 0.87 0.307 0.0687 1.15 1.4325 0.9905 3179737 Maybridge4_004061 Fc1cc(C(=O)NCc2ccc(cc2)N3CCOCC3)c4OCOCc4c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I14 compound treatment 0.243 0.023 0.33 0.28 0.0417 0.7 0.7277 0.9407 3179738 Maybridge4_004062 Cc1cc(NC(=O)/C(=C/c2cccs2)/c3ccsc3)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I15 compound treatment 0.259 0.039 0.56 0.222 -0.0163 -0.27 0.2012 0.3239 3064816 Maybridge4_004063 COC(=O)C/1=NN(C(=O)\C1=N/O)c2c(C)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I16 compound treatment 0.211 -0.009 -0.13 0.208 -0.0303 -0.51 -0.4504 -0.8591 3064817 Maybridge4_004064 COC(=O)C/1=NN(C(=O)\C1=C/N(C)C)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I17 compound treatment 0.249 0.029 0.41 0.213 -0.0253 -0.42 -0.0067 -0.0113 3064818 Maybridge4_004065 FC(F)(F)c1cc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)cc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I18 compound treatment 0.256 0.036 0.51 0.272 0.0337 0.57 0.7643 0.9989 3064819 Maybridge4_004066 OC(=O)c1coc2CCC/C(=N\N3CCCCC3)/c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I19 compound treatment 0.222 0.002 0.03 0.238 -2.81E-4 0.0 0.0169 0.5825 1604639 Maybridge4_004067 CNC(=S)NCc1ccc(cc1)c2csnn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I20 compound treatment 0.233 0.013 0.19 0.225 -0.0133 -0.22 -0.0261 -0.09 3064820 Maybridge4_004068 FC(F)(F)c1cccc(/C=N/Cc2ccc(s2)c3cccs3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I21 compound treatment 0.235 0.015 0.21 0.274 0.0357 0.6 0.5756 0.904 3064821 Maybridge4_004069 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)Oc2ccc(cc2)c3csnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I22 compound treatment 0.224 0.004 0.06 0.266 0.0277 0.47 0.3694 0.7881 3064822 Maybridge4_004070 COc1cc(/C=C\2/N=C(C)OC2=O)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I23 mock treatment 0.222 0.002 0.03 0.214 -0.0243 -0.41 -0.2679 -0.6559 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 I24 mock treatment 0.194 -0.026 -0.37 0.171 -0.0673 -1.13 -1.0615 -0.8928 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J01 compound treatment 0.21 -0.01 -0.14 0.271 0.0327 0.55 0.2872 0.506 3064823 Maybridge4_004071 CSc1cc(n[nH]1)c2nccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J02 compound treatment 0.258 0.038 0.54 0.342 0.104 1.74 1.6153 0.8857 3179739 Maybridge4_004072 CC(C)c1ccc(C)c2c(/C=C(/C#N)\S(=O)(=O)C)cc(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J03 compound treatment 0.28 0.06 0.86 0.273 0.0347 0.58 1.0189 0.9822 3064824 Maybridge4_004073 Nc1nc2c(c(sc2s1)C(F)(F)F)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J04 compound treatment 0.261 0.041 0.59 0.263 0.0247 0.41 0.708 0.9856 3179740 Maybridge4_004074 NC(=S)Nc1ccc(cc1Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J05 compound treatment 0.276 0.056 0.8 0.31 0.0717 1.2 1.4176 0.9804 3179741 Maybridge4_004075 COC(=O)c1sc(c(c1S(=O)(=O)N2CCOCC2)c3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J06 compound treatment 0.291 0.071 1.02 0.207 -0.0313 -0.53 0.3469 0.3034 3064825 Maybridge4_004076 CC(C)N(C(C)C)C(=O)c1ccc(cc1)c2ccccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J07 compound treatment 0.288 0.068 0.97 0.271 0.0327 0.55 1.0761 0.9634 1125107 Maybridge4_004077 Clc1snnc1CN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J08 compound treatment 0.306 0.086 1.23 0.33 0.0917 1.54 1.9583 0.9938 3179742 Maybridge4_004078 Clc1ccc(Sc2ccc(C#N)cn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J09 compound treatment 0.257 0.037 0.53 0.259 0.0207 0.35 0.6201 0.9792 3179743 Maybridge4_004079 COc1cc(cc(OC)c1OC)C(=O)OC(Cc2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J10 compound treatment 0.267 0.047 0.67 0.246 0.00772 0.13 0.567 0.8281 1420510 Maybridge4_004080 NC(=S)c1nc(oc1N)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J11 compound treatment 0.28 0.06 0.86 0.276 0.0377 0.63 1.0545 0.9888 3064826 Maybridge4_004081 CCOC(=O)Cc1csc(n1)c2ncc(cc2Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J12 compound treatment 0.254 0.034 0.49 0.3 0.0617 1.04 1.0764 0.9406 1571322 Maybridge4_004082 CCN(CC)c1ccc(NC(=O)C2CCCCC2)c(n1)N(CC)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J13 compound treatment 0.225 0.005 0.07 0.292 0.0537 0.9 0.6881 0.7608 3064827 Maybridge4_004083 CC(C)(C)Cc1nc(no1)C2(CC2)c3ccc(Cl)cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J14 compound treatment 0.208 -0.012 -0.17 0.22 -0.0183 -0.31 -0.3383 -0.9623 3179744 Maybridge4_004084 CN(C)c1ccc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)cc1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J15 compound treatment 0.253 0.033 0.47 0.304 0.0657 1.1 1.1137 0.9283 1672501 Maybridge4_004085 O=C(NC(=O)N1CCCC1)C2CCN(CC2)c3cnc4ccccc4n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J16 compound treatment 0.248 0.028 0.4 0.264 0.0257 0.43 0.5884 0.9993 3064828 Maybridge4_004086 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J17 compound treatment 0.322 0.102 1.46 0.27 0.0317 0.53 1.4081 0.9067 1716306 Maybridge4_004087 O=C(C1CCN(CC1)C(=O)c2ccco2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J18 compound treatment 0.263 0.043 0.62 0.293 0.0547 0.92 1.0843 0.981 1727489 Maybridge4_004088 Cc1ccc(F)cc1N2CC(CC2=O)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J19 compound treatment 0.222 0.002 0.03 0.236 -0.00228 -0.04 -0.0068 -0.1432 3179745 Maybridge4_004089 Clc1ccc(/C=C/2\COC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J20 compound treatment 0.218 -0.002 -0.03 0.225 -0.0133 -0.22 -0.1779 -0.7914 1700558 Maybridge4_004090 CC(C)(C)c1ccc(cc1)C(=O)N2CCC(CC2)c3nc(no3)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J21 compound treatment 0.274 0.054 0.77 0.252 0.0137 0.23 0.709 0.8796 3064829 Maybridge4_004091 Fc1ccc(NC(=O)Cc2cc(F)cc(F)c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J22 compound treatment 0.245 0.025 0.36 0.282 0.0437 0.73 0.7717 0.9454 3064830 Maybridge4_004092 CC(C)(C)c1nnc(o1)c2cccc(NS(=O)(=O)c3ccc(s3)c4ccon4)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J23 mock treatment 0.218 -0.002 -0.03 0.24 0.00172 0.03 2.0E-4 0.0042 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 J24 mock treatment 0.205 -0.015 -0.21 0.187 -0.0513 -0.86 -0.7603 -0.8571 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K01 compound treatment 0.252 0.032 0.46 0.307 0.0687 1.15 1.1392 0.9181 3179746 Maybridge4_004093 Clc1ccc(cc1)S(=O)(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K02 compound treatment 0.246 0.026 0.37 0.32 0.0817 1.37 1.2328 0.8675 3179747 Maybridge4_004094 FC(F)(F)c1ccc(cc1)C(=O)Nc2cccc(c2)c3nnco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K03 compound treatment 0.253 0.033 0.47 0.292 0.0537 0.9 0.9713 0.9544 3064831 Maybridge4_004095 O=S(=O)(NCC1COc2ccccc2O1)c3ccc(nc3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K04 compound treatment 0.31 0.09 1.29 0.277 0.0387 0.65 1.3698 0.9499 1348923 Maybridge4_004096 Cc1cc(NC(=O)CCOc2ccc(F)cc2)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K05 compound treatment 0.244 0.024 0.34 0.282 0.0437 0.73 0.7616 0.9401 3179748 Maybridge4_004097 Cc1cc(c(C)o1)S(=O)(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K06 compound treatment 0.258 0.038 0.54 0.244 0.00572 0.1 0.4522 0.8193 1281685 Maybridge4_004098 NC(=O)c1cnc2SCCn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K07 compound treatment 0.305 0.085 1.22 0.259 0.0207 0.35 1.1056 0.8743 3064832 Maybridge4_004099 COc1ccc(cc1)C(=O)NCc2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K08 compound treatment 0.25 0.03 0.43 0.282 0.0437 0.73 0.8223 0.9674 3179749 Maybridge4_004100 CC(C)(C)c1csc(n1)c2sccc2CS(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K09 compound treatment 0.287 0.067 0.96 0.28 0.0417 0.7 1.1728 0.9881 3179750 Maybridge4_004101 COc1ccccc1CC(=O)NCc2nn(nc2C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K10 compound treatment 0.323 0.103 1.47 0.298 0.0597 1.0 1.7505 0.9824 3064834 Maybridge4_004102 FC(F)(F)c1ccc(SCCS(=O)(=O)CCSc2ccc(cn2)C(F)(F)F)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K11 compound treatment 0.303 0.083 1.19 0.3 0.0617 1.04 1.572 0.9977 3179751 Maybridge4_004103 Cc1noc(C)c1S(=O)(=O)NCc2nn(nc2C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K12 compound treatment 0.264 0.044 0.63 0.269 0.0307 0.52 0.8096 0.9951 3064714 Maybridge4_004104 OC(=O)c1ncoc1c2cccc(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K13 compound treatment 0.302 0.082 1.17 0.27 0.0317 0.53 1.2058 0.9361 1121050 Maybridge4_004105 CCOC(=O)c1c(NC(=O)C)nc(SC)n1Cc2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K14 compound treatment 0.286 0.066 0.94 0.254 0.0157 0.26 0.8541 0.8713 3179752 Maybridge4_004106 FC(F)(F)c1ccc(SC(=O)/C(=C\c2cccs2)/c3ccsc3)nc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K15 compound treatment 0.229 0.009 0.13 0.27 0.0317 0.53 0.4675 0.8535 3064716 Maybridge4_004107 CCOC(=O)c1n[nH]c(=S)[nH]c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K16 compound treatment 0.267 0.047 0.67 0.258 0.0197 0.33 0.7094 0.9467 3179753 Maybridge4_004108 COC(=O)c1nn(c2ccccc2)c3oc(=O)cc(C)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K17 compound treatment 0.272 0.052 0.74 0.229 -0.00928 -0.16 0.4158 0.5471 3064717 Maybridge4_004109 CC(C)(C)S(=O)(=O)/C(=C/c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K18 compound treatment 0.165 -0.055 -0.79 0.128 -0.11 -1.85 -1.8651 -0.9274 3179754 Maybridge4_004110 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K19 compound treatment 0.254 0.034 0.49 0.246 0.00772 0.13 0.4355 0.8653 3064769 Maybridge4_004111 CC1=NN(C(=O)C1)c2ccc(cc2)c3csnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K20 compound treatment 0.218 -0.002 -0.03 0.229 -0.00928 -0.16 -0.1304 -0.8232 1351476 Maybridge4_004112 Fc1ccccc1NC(=O)NCc2sccc2COc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K21 compound treatment 0.196 -0.024 -0.34 0.208 -0.0303 -0.51 -0.6021 -0.9817 3064771 Maybridge4_004113 CCCC1N(CCc2sccc12)C(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K22 compound treatment 0.232 0.012 0.17 0.251 0.0127 0.21 0.2723 0.9942 3179755 Maybridge4_004114 COc1cc(/C=C(\NC(=O)C)/C(=O)O)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K23 mock treatment 0.239 0.019 0.27 0.26 0.0217 0.36 0.4499 0.9895 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 K24 mock treatment 0.229 0.009 0.13 0.256 0.0177 0.3 0.3013 0.9298 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L01 compound treatment 0.267 0.047 0.67 0.222 -0.0163 -0.27 0.2821 0.3888 3064772 Maybridge4_004115 FC(F)(F)c1sc(cc1c2ccccc2)C(=O)Oc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L02 compound treatment 0.225 0.005 0.07 0.314 0.0757 1.27 0.9492 0.7457 3179756 Maybridge4_004116 NC(=S)c1ccc(s1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L03 compound treatment 0.274 0.054 0.77 0.325 0.0867 1.46 1.5754 0.9561 3179757 Maybridge4_004117 COc1ccc(SCc2nsc(Sc3ccc(OC)cc3)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L04 compound treatment 0.229 0.009 0.13 0.292 0.0537 0.9 0.7286 0.8 3064773 Maybridge4_004118 OC(=O)c1c-2c(CSc3ccc(Cl)cc32)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L05 compound treatment 0.276 0.056 0.8 0.274 0.0357 0.6 0.9903 0.9898 3179758 Maybridge4_004119 CSC(=N)Nc1csc(c1c2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L06 compound treatment 0.278 0.058 0.83 0.227 -0.0113 -0.19 0.4527 0.532 3179759 Maybridge4_004120 O=C/1Nc2ccccc2\C1=C/c3ccccc3N4CCN(Cc5ccccc5)CC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L07 compound treatment 0.159 -0.061 -0.87 0.053 -0.185 -3.11 -2.8159 -0.8718 3064774 Maybridge4_004121 NC(=S)c1cc(c(s1)C(F)(F)F)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L08 compound treatment 0.28 0.06 0.86 0.292 0.0537 0.9 1.2444 0.9997 3064775 Maybridge4_004122 CCOC(=O)Cc1c(C#N)c(N)sc1C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L09 compound treatment 0.303 0.083 1.19 0.295 0.0567 0.95 1.5126 0.994 3179760 Maybridge4_004123 FC(F)(F)C(Cc1ccccc1)OC(=O)c2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L10 compound treatment 0.244 0.024 0.34 0.266 0.0277 0.47 0.5717 0.9888 3064776 Maybridge4_004124 CC(C)(C)c1ccc(s1)C(=O)Nc2ccc(cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L11 compound treatment 0.168 -0.052 -0.74 0.152 -0.0863 -1.45 -1.5499 -0.9521 3178169 Maybridge4_004125 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)CSc4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L12 compound treatment 0.259 0.039 0.56 0.276 0.0377 0.63 0.8421 0.998 3178170 Maybridge4_004126 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(NC(=O)c4cccs4)cn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L13 compound treatment 0.293 0.073 1.04 0.27 0.0317 0.53 1.1148 0.9511 3064777 Maybridge4_004127 FC(F)(F)c1ccnc(c1)c2ccc(s2)S(=O)(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L14 compound treatment 0.234 0.014 0.2 0.239 7.19E-4 0.01 0.1501 0.7483 3064778 Maybridge4_004128 CC1(C)OC(=O)C(=Cc2cccn2c3ccc(cc3)C(F)(F)F)C(=O)O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L15 compound treatment 0.238 0.018 0.26 0.274 0.0357 0.6 0.606 0.9288 3178171 Maybridge4_004129 Cc1onc(c1NC(=O)OCCOc2cc(ccn2)C(F)(F)F)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L16 compound treatment 0.193 -0.027 -0.39 0.17 -0.0683 -1.15 -1.0835 -0.8959 3178172 Maybridge4_004130 CC(C)Cc1ccc(cc1)C(C)C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L17 compound treatment 0.279 0.059 0.84 0.284 0.0457 0.77 1.1393 0.9989 1466123 Maybridge4_004131 Clc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L18 compound treatment 0.291 0.071 1.02 0.308 0.0697 1.17 1.5455 0.9975 3178173 Maybridge4_004132 CS(=O)(=O)/C(=C/c1cccn1c2ccc(OC(F)(F)F)cc2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L19 compound treatment 0.267 0.047 0.67 0.266 0.0277 0.47 0.8043 0.9838 3064779 Maybridge4_004133 Clc1ccc(C(=O)n2cc3COCCc3n2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L20 compound treatment 0.264 0.044 0.63 0.256 0.0177 0.3 0.6553 0.9414 3178174 Maybridge4_004134 CC(C)(C)c1cc(n(n1)c2ccc(cc2)C(=O)NN)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L21 compound treatment 0.256 0.036 0.51 0.3 0.0617 1.04 1.0966 0.9479 3064780 Maybridge4_004135 OC(=O)CCc1ccc(Cl)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L22 compound treatment 0.194 -0.026 -0.37 0.205 -0.0333 -0.56 -0.658 -0.9805 1339700 Maybridge4_004136 Cc1onc(c1c2nc(CSc3nc4ccccc4[nH]3)no2)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L23 mock treatment 0.26 0.04 0.57 0.234 -0.00428 -0.07 0.3538 0.6135 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 L24 mock treatment 0.195 -0.025 -0.36 0.236 -0.00228 -0.04 -0.2799 -0.7784 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M01 compound treatment 0.279 0.059 0.84 0.281 0.0427 0.72 1.1037 0.9967 3178175 Maybridge4_004137 CCc1ccc(cc1)S(=O)(=O)NC2CCCCNC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M02 compound treatment 0.357 0.137 1.96 0.364 0.126 2.11 2.8777 0.9993 3064835 Maybridge4_004138 CC/1Sc2ccc(Cl)cc2C(=O)\C1=C\N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M03 compound treatment 0.272 0.052 0.74 0.254 0.0157 0.26 0.7125 0.9028 3178176 Maybridge4_004139 O=S(=O)(N(Cc1ccccn1)Cc2ccccn2)c3ccc(nc3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M04 compound treatment 0.279 0.059 0.84 0.272 0.0337 0.57 0.9969 0.9811 3064836 Maybridge4_004140 Cn1cnnc1SCc2ccc(cc2)c3csnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M05 compound treatment 0.271 0.051 0.73 0.286 0.0477 0.8 1.0822 0.9989 3178177 Maybridge4_004141 O=C(N1CCCCCC1)c2ccc(nc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M06 compound treatment 0.323 0.103 1.47 0.293 0.0547 0.92 1.6912 0.9741 3064837 Maybridge4_004142 COC(=O)c1cc(C)cc(=O)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M07 compound treatment 0.263 0.043 0.62 0.299 0.0607 1.02 1.1555 0.9708 3064839 Maybridge4_004143 Fc1ccc(cc1F)S(=O)(=O)NCc2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M08 compound treatment 0.31 0.09 1.29 0.281 0.0427 0.72 1.4173 0.9618 1167482 Maybridge4_004144 Cc1nc(C)c(o1)c2ccnc(n2)C3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M09 compound treatment 0.257 0.037 0.53 0.313 0.0747 1.25 1.261 0.9264 3178178 Maybridge4_004145 CN(C)c1ccc(cc1)C(=O)NCc2nn(nc2C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M10 compound treatment 0.233 0.013 0.19 0.272 0.0337 0.57 0.5317 0.8925 1335790 Maybridge4_004146 CN(C)c1c(F)cc(cc1F)C(=O)NC(=O)NCc2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M11 compound treatment 0.229 0.009 0.13 0.29 0.0517 0.87 0.7048 0.8032 3178179 Maybridge4_004147 COc1ccc(OC)c(c1)S(=O)(=O)NCc2nn(nc2C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M12 compound treatment 0.205 -0.015 -0.21 0.233 -0.00528 -0.09 -0.2144 -0.9235 3064841 Maybridge4_004148 CN(C)c1c(/C=C(/C#N)\S(=O)(=O)C)cc(/C=C(/C#N)\S(=O)(=O)C)c(N(C)C)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M13 compound treatment 0.33 0.11 1.57 0.271 0.0327 0.55 1.5009 0.9006 3178180 Maybridge4_004149 CSc1nsc(SC)c1C(=O)NC(=O)N2CCSCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M14 compound treatment 0.321 0.101 1.44 0.317 0.0787 1.32 1.9558 0.999 1166894 Maybridge4_004150 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2csc(c2)S(=O)(=O)N3CCSCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M15 compound treatment 0.231 0.011 0.16 0.247 0.00872 0.15 0.2147 0.9993 3064844 Maybridge4_004151 COC(=O)c1sc(cc1CS(=O)(=O)c2cc(C)c(Cl)cc2C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M16 compound treatment 0.042 -0.178 -2.55 0.269 0.0307 0.52 -1.4358 -0.5527 3178181 Maybridge4_004152 Sc1nccc(n1)c2ccc(s2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M17 compound treatment 0.262 0.042 0.6 0.206 -0.0323 -0.54 0.0417 0.0515 1462127 Maybridge4_004153 Fc1ccc(C(=O)Nc2ccc(cc2)c3cnco3)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M18 compound treatment 0.15 -0.07 -1.0 0.148 -0.0903 -1.52 -1.7795 -0.9798 3178182 Maybridge4_004154 Cc1ccccc1C(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M19 compound treatment 0.271 0.051 0.73 0.266 0.0277 0.47 0.8448 0.9764 1245747 Maybridge4_004155 Clc1ccc(cc1)C2=NCCc3sccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M20 compound treatment 0.269 0.049 0.7 0.267 0.0287 0.48 0.8364 0.9833 3178183 Maybridge4_004156 Clc1ccc(OCc2ccsc2Cn3cccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M21 compound treatment 0.213 -0.007 -0.1 0.269 0.0307 0.52 0.2938 0.5593 1431141 Maybridge4_004157 CCCC1N(CCc2sccc12)C(=O)c3cc(OC)cc(OC)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M22 compound treatment 0.268 0.048 0.69 0.244 0.00572 0.1 0.5534 0.7982 3178184 Maybridge4_004158 Clc1ccc(SC(=O)c2ccc(s2)c3cccs3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M23 mock treatment 0.257 0.037 0.53 0.221 -0.0173 -0.29 0.1691 0.2802 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 M24 mock treatment 0.204 -0.016 -0.23 0.247 0.00872 0.15 -0.0584 -0.2148 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N01 compound treatment 0.235 0.015 0.21 0.243 0.00472 0.08 0.2077 0.9082 3064890 Maybridge4_004159 C/C(=N\O)/c1cc(c(s1)C(F)(F)F)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N02 compound treatment 0.211 -0.009 -0.13 0.247 0.00872 0.15 0.0124 0.0639 3178185 Maybridge4_004160 CC(C)(C)c1csc(n1)c2ccc(s2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N03 compound treatment 0.161 -0.059 -0.84 0.093 -0.145 -2.44 -2.321 -0.8995 3064891 Maybridge4_004161 FC(F)(F)c1sc(COC(=O)Nc2ccccc2)cc1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N04 compound treatment 0.215 -0.005 -0.07 0.245 0.00672 0.11 0.0292 0.2184 3178186 Maybridge4_004162 FC(F)(F)c1ccc(Cl)c(c1)c2ccc(o2)C(C3C(=O)CCCC3=O)C4C(=O)CCCC4=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N05 compound treatment 0.279 0.059 0.84 0.304 0.0657 1.1 1.3767 0.9913 3064893 Maybridge4_004163 COc1ccc(SCc2cc3c(F)c(F)c(F)c(F)c3o2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N06 compound treatment 0.28 0.06 0.86 0.294 0.0557 0.94 1.2681 0.9991 3178187 Maybridge4_004164 Cc1noc(C)c1C(=O)n2cc3CSc4ccc(F)cc4-c3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N07 compound treatment 0.043 -0.177 -2.53 0.043 -0.195 -3.28 -4.1078 -0.9919 3064894 Maybridge4_004165 FC(F)(F)/C(=C(\C#N)/c1ccccc1)/Oc2ccc(C#N)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N08 compound treatment 0.203 -0.017 -0.24 0.205 -0.0333 -0.56 -0.5669 -0.9306 3178188 Maybridge4_004166 Cc1oc(N)c(c1C)S(=O)(=O)/C(=C/c2cc(Cl)cc(Cl)c2)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N09 compound treatment 0.295 0.075 1.07 0.318 0.0797 1.34 1.7047 0.994 3178189 Maybridge4_004167 CCOC(=O)c1ccc2C(=O)/C(=C/c3ccc(Cl)cc3Cl)/CCc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N10 compound treatment 0.246 0.026 0.37 0.331 0.0927 1.56 1.3634 0.8521 1967416 Maybridge4_004168 OC(=O)CCC(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N11 compound treatment 0.315 0.095 1.36 0.318 0.0797 1.34 1.907 1.0 3064896 Maybridge4_004169 Clc1ccc(SCc2csc(n2)c3ccsc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N12 compound treatment 0.283 0.063 0.9 0.249 0.0107 0.18 0.7644 0.8319 3178190 Maybridge4_004170 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(NC(=O)/C=C/c4ccccc4)cn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N13 compound treatment 0.249 0.029 0.41 0.309 0.0707 1.19 1.1326 0.9008 3064897 Maybridge4_004171 CN(C)/C=N/C(=S)N1CCOCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N14 compound treatment 0.3 0.08 1.14 0.318 0.0797 1.34 1.7552 0.997 3178191 Maybridge4_004172 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCc4c([nH]c5ccccc45)C3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N15 compound treatment 0.249 0.029 0.41 0.27 0.0317 0.53 0.6698 0.9924 1192815 Maybridge4_004173 O=C(NC(=S)Nc1ccncc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N16 compound treatment 0.305 0.085 1.22 0.305 0.0667 1.12 1.6515 0.9992 3064898 Maybridge4_004174 CS(=O)(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N17 compound treatment 0.288 0.068 0.97 0.27 0.0317 0.53 1.0642 0.9598 1131475 Maybridge4_004175 Clc1ccc(NC(=O)N2CCC(CC2)C(=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N18 compound treatment 0.299 0.079 1.13 0.266 0.0277 0.47 1.128 0.9231 1346023 Maybridge4_004176 Cc1ccc(cc1)S(=O)(=O)NC(=O)Oc2ccc(cc2)c3csnn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N19 compound treatment 0.114 -0.106 -1.52 0.125 -0.113 -1.9 -2.4165 -0.9937 3178192 Maybridge4_004177 S=C(SCc1ncon1)N2CCSCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N20 compound treatment 0.328 0.108 1.54 0.283 0.0447 0.75 1.6231 0.945 3178193 Maybridge4_004178 Cc1ccc(C)n1CCSCc2c(C)cc(C)cc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N21 compound treatment 0.295 0.075 1.07 0.3 0.0617 1.04 1.4911 0.9998 1202142 Maybridge4_004179 CCOC(=O)c1c(C)nn(c1C)c2ncccc2NC(=O)CCC(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N22 compound treatment 0.229 0.009 0.13 0.278 0.0397 0.67 0.5624 0.8284 1591050 Maybridge4_004180 CCOC(=O)c1[nH]c2ccc(cc2c1CCC(=O)O)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N23 mock treatment 0.292 0.072 1.03 0.291 0.0527 0.88 1.3539 0.9971 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 N24 mock treatment 0.233 0.013 0.19 0.202 -0.0363 -0.61 -0.2991 -0.4698 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O01 compound treatment 0.274 0.054 0.77 0.254 0.0157 0.26 0.7327 0.8977 3178270 Maybridge4_004181 COc1cc2CCN(Cc2cc1OC)C(=O)c3sc(nc3C)c4cnccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O02 compound treatment 0.284 0.064 0.92 0.245 0.00672 0.11 0.727 0.7883 1317839 Maybridge4_004182 CC(C)(C)c1ccc(s1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O03 compound treatment 0.252 0.032 0.46 0.3 0.0617 1.04 1.0561 0.9326 3064900 Maybridge4_004183 COc1ccc(cc1)n2ncc(C(=O)Nc3ccc4nccnc4c3)c2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O04 compound treatment 0.271 0.051 0.73 0.33 0.0917 1.54 1.6044 0.9418 3178271 Maybridge4_004184 N/C(=N/O)/c1cnc2SCCn2c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O05 compound treatment 0.256 0.036 0.51 0.306 0.0677 1.14 1.1678 0.9359 3178272 Maybridge4_004185 O=C(N1CCSCC1)c2ccc(nc2)N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O06 compound treatment 0.266 0.046 0.66 0.306 0.0677 1.14 1.2689 0.9662 3064901 Maybridge4_004186 NC(=S)c1ccc(cc1Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O07 compound treatment 0.235 0.015 0.21 0.259 0.0207 0.35 0.3976 0.9731 3178273 Maybridge4_004187 O=S(=O)(NCc1ccc(cc1)c2cccs2)c3ccc(nc3)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O08 compound treatment 0.23 0.01 0.14 0.297 0.0587 0.99 0.798 0.8013 3064932 Maybridge4_004188 CN(C)c1ccc(/C=C(\C#N)/S(=O)(=O)C)c(F)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O09 compound treatment 0.212 -0.008 -0.11 0.281 0.0427 0.72 0.4261 0.5868 3178274 Maybridge4_004189 Cc1nn(nc1CNC(=O)c2cccs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O10 compound treatment 0.216 -0.004 -0.06 0.288 0.0497 0.83 0.5496 0.6571 3178275 Maybridge4_004190 CN(C)c1c(F)cc(cc1F)C(=O)NC(=O)NC2=NCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O11 compound treatment 0.258 0.038 0.54 0.221 -0.0173 -0.29 0.1792 0.2909 3064933 Maybridge4_004191 Cc1noc(C)c1NC(=O)NCc2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O12 compound treatment 0.268 0.048 0.69 0.288 0.0497 0.83 1.0755 0.9953 3064934 Maybridge4_004192 NNC(=O)c1cc2sccc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O13 compound treatment 0.2 -0.02 -0.29 0.271 0.0327 0.55 0.186 0.3004 3178276 Maybridge4_004193 CSc1nsc(SC)c1C(=O)NC(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O14 compound treatment 0.305 0.085 1.22 0.324 0.0857 1.44 1.877 0.9965 1408005 Maybridge4_004194 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2csc(c2)S(=O)(=O)Nc3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O15 compound treatment 0.23 0.01 0.14 0.292 0.0537 0.9 0.7387 0.8092 3064936 Maybridge4_004195 COC(=O)c1sc(cc1CS(=O)(=O)c2ccccn2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O16 compound treatment 0.231 0.011 0.16 0.295 0.0567 0.95 0.7844 0.8129 3178277 Maybridge4_004196 COc1ccc(cc1OC)S(=O)(=O)n2nccc2c3ccc(s3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O17 compound treatment 0.221 0.001 0.01 0.293 0.0547 0.92 0.6595 0.718 3064939 Maybridge4_004197 Clc1ccc(NC(=S)Nc2ccc(cc2)c3csnn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O18 compound treatment 0.241 0.021 0.3 0.246 0.00772 0.13 0.304 0.9293 3178278 Maybridge4_004198 Clc1cccc(Cl)c1C(=O)NCc2ccc(s2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O19 compound treatment 0.225 0.005 0.07 0.234 -0.00428 -0.07 -2.0E-4 -0.0024 3064941 Maybridge4_004199 CNC(=S)N1CCc2sccc2C1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O20 compound treatment 0.213 -0.007 -0.1 0.243 0.00472 0.08 -0.0148 -0.1159 3178279 Maybridge4_004200 CS/C(=N\C#N)/NCc1sccc1COc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O21 compound treatment 0.227 0.007 0.1 0.224 -0.0143 -0.24 -0.0987 -0.3799 1659450 Maybridge4_004201 O=C(NC(=O)c1ccc(cc1)c2csnn2)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O22 compound treatment 0.259 0.039 0.56 0.251 0.0127 0.21 0.5454 0.9131 3178280 Maybridge4_004202 CN(C)/C=N\C(=S)c1sccc1CSc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O23 mock treatment 0.199 -0.021 -0.3 0.234 -0.00428 -0.07 -0.2632 -0.8522 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 O24 mock treatment 0.192 -0.028 -0.4 0.203 -0.0353 -0.59 -0.7019 -0.9819 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P01 compound treatment 0.215 -0.005 -0.07 0.281 0.0427 0.72 0.4564 0.6334 1411380 Maybridge4_004203 COC(=O)c1cc(=O)n2ccccc2c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P02 compound treatment 0.301 0.081 1.16 0.294 0.0557 0.94 1.4805 0.9944 3178281 Maybridge4_004204 CN(C)/C=N/C(=S)c1ccc(s1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P03 compound treatment 0.223 0.003 0.04 0.281 0.0427 0.72 0.5373 0.7481 3178282 Maybridge4_004205 CCOC(=O)c1c(CS(=O)(=O)Cc2ccc(Cl)cc2)oc3c(F)c(F)c(F)c(F)c13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P04 compound treatment 0.272 0.052 0.74 0.303 0.0647 1.09 1.294 0.9829 1195874 Maybridge4_004206 COc1ccc(CN(Cc2cc(OC)c(OC)c(OC)c2)C(=O)C(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P05 compound treatment 0.252 0.032 0.46 0.31 0.0717 1.2 1.1748 0.9123 3178283 Maybridge4_004207 COC(=O)c1sc(c(c1S(=O)(=O)NC(C)(C)C)c2ccccc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P06 compound treatment 0.122 -0.098 -1.4 0.139 -0.0993 -1.67 -2.1695 -0.9963 3064943 Maybridge4_004208 OC1=C(C(=O)c2ccccc12)c3cc(Cl)cc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P07 compound treatment 0.221 0.001 0.01 0.213 -0.0253 -0.42 -0.2899 -0.6829 3064944 Maybridge4_004209 CSc1ccc(/C=C\2/C(=NN(C)C2=O)C)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P08 compound treatment 0.23 0.01 0.14 0.308 0.0697 1.17 0.9286 0.7877 1179765 Maybridge4_004210 Cc1noc(C)c1NC(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P09 compound treatment 0.232 0.012 0.17 0.341 0.103 1.72 1.3404 0.7737 3064945 Maybridge4_004211 FC(F)(F)Oc1ccc(NC(=O)C=C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P10 compound treatment 0.252 0.032 0.46 0.227 -0.0113 -0.19 0.1898 0.3831 3178284 Maybridge4_004212 CC(C)(C)SCc1cccc(c1)C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P11 compound treatment 0.231 0.011 0.16 0.257 0.0187 0.31 0.3334 0.9489 3178285 Maybridge4_004213 OC(=O)c1cccnc1C(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P12 compound treatment 0.223 0.003 0.04 0.246 0.00772 0.13 0.1219 0.8936 3178286 Maybridge4_004214 O/N=C/c1ccc(Cl)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P13 compound treatment 0.268 0.048 0.69 0.338 0.0997 1.67 1.669 0.9226 3178287 Maybridge4_004215 CC(C)(C)NC(=O)N1CCN(CC1)c2cc(ccn2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P14 compound treatment 0.183 -0.037 -0.53 0.206 -0.0323 -0.54 -0.7573 -0.9999 3064989 Maybridge4_004216 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=S)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P15 compound treatment 0.308 0.088 1.26 0.315 0.0767 1.29 1.8006 0.9999 3178288 Maybridge4_004217 CN(C(=S)NC(=O)c1ccccc1)c2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P16 compound treatment 0.228 0.008 0.11 0.265 0.0267 0.45 0.398 0.86 3064991 Maybridge4_004218 FC(F)(F)c1ccc(nc1)N2CCN(CC2)C(=O)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P17 compound treatment 0.25 0.03 0.43 0.229 -0.00928 -0.16 0.1933 0.4234 3178289 Maybridge4_004219 Cc1cc(C)n(n1)c2ccc(cc2)n3cccc3/C=C(/C#N)\S(=O)(=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P18 compound treatment 0.24 0.02 0.29 0.281 0.0427 0.72 0.7093 0.9188 3178290 Maybridge4_004220 OC(=O)CCCC(=O)Nc1ccccc1SCc2noc(n2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P19 compound treatment 0.266 0.046 0.66 0.317 0.0787 1.32 1.3995 0.9482 1467411 Maybridge4_004221 Fc1ccc(CSC(=S)N2CCN(CC2)C(=S)SCc3ccc(F)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P20 compound treatment 0.251 0.031 0.44 0.249 0.0107 0.18 0.4408 0.9211 3064993 Maybridge4_004222 CC(C)n1nc(cc1C(C)(C)C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P21 compound treatment 0.32 0.1 1.43 0.305 0.0667 1.12 1.8032 0.9927 3178291 Maybridge4_004223 Cn1nc(c(c1N2C(=O)C3C4CC(C=C4)C3C2=O)c5ccccc5)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P22 compound treatment 0.268 0.048 0.69 0.275 0.0367 0.62 0.9213 0.9985 3178292 Maybridge4_004224 COC(=O)c1cc(/C=C/C(=O)N(C2CCCCC2)C(=O)NC3CCCCC3)cn1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P23 mock treatment 0.261 0.041 0.59 0.238 -2.81E-4 0.0 0.4113 0.7014 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2060 P24 mock treatment 0.221 0.001 0.01 0.238 -2.81E-4 0.0 0.0068 0.4499 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A01 compound treatment 0.241 -0.0247 -0.35 0.222 -0.0199 -0.33 -0.4866 -0.9996 1382867 Maybridge4_004225 C1Oc2ccc(cc2O1)C3Nc4ccccc4S3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A02 compound treatment 0.293 0.0273 0.39 0.216 -0.0259 -0.44 -0.0319 -0.0545 3064994 Maybridge4_004226 CN(C)C(=O)Oc1nnc(SCc2ccc(C)cc2)n1c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A03 compound treatment 0.293 0.0273 0.39 0.223 -0.0189 -0.32 0.0512 0.1018 1421127 Maybridge4_004227 Cc1c(cc(c2ccccc2)n1c3ccccc3)C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A04 compound treatment 0.239 -0.0267 -0.38 0.216 -0.0259 -0.44 -0.578 -0.9979 3178293 Maybridge4_004228 CC(C)Sc1nnc(OC(=O)N(C)C)n1c2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A05 compound treatment 0.285 0.0193 0.28 0.198 -0.0439 -0.74 -0.3264 -0.4145 1234864 Maybridge4_004229 N#Cc1ccc(cc1)c2csc(n2)c3ccc(cc3)C4SCCS4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A06 compound treatment 0.31 0.0443 0.63 0.197 -0.0449 -0.75 -0.0854 -0.0867 3178294 Maybridge4_004230 CSc1nnc(O)c2cc(C)nn12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A07 compound treatment 0.3 0.0343 0.49 0.215 -0.0269 -0.45 0.0271 0.0406 3064995 Maybridge4_004231 Cc1ccc(cc1)c2csc(COC(=O)C(C)(C)C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A08 compound treatment 0.325 0.0593 0.85 0.242 6.25E-5 0.0 0.6004 0.708 3178295 Maybridge4_004232 Fc1ccc(Cn2ccnc2c3ccc(cc3)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A09 compound treatment 0.24 -0.0257 -0.37 0.223 -0.0189 -0.32 -0.4848 -0.9974 3064997 Maybridge4_004233 CCn1nc(C)c(Br)c1c2nc(no2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A10 compound treatment 0.246 -0.0197 -0.28 0.199 -0.0429 -0.72 -0.709 -0.9162 3178296 Maybridge4_004234 Cc1nc(C)c(s1)c2nnc(S)n2c3ccccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A11 compound treatment 0.231 -0.0347 -0.5 0.199 -0.0429 -0.72 -0.8607 -0.9835 1124397 Maybridge4_004235 Cc1oc(cc1c2cc(N)n(n2)c3ccc(cc3)S(=O)(=O)N)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A12 compound treatment 0.229 -0.0367 -0.53 0.209 -0.0329 -0.55 -0.7622 -0.9997 3064998 Maybridge4_004236 Cn1c(SCc2ccc(cc2)C(F)(F)F)nnc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A13 compound treatment 0.209 -0.0567 -0.81 0.217 -0.0249 -0.42 -0.8696 -0.9526 3178384 Maybridge4_004237 Cc1n(CCSCc2c(F)cccc2Cl)c(c3ccccc3)c4cn[nH]c(=O)c14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A14 compound treatment 0.171 -0.0947 -1.35 0.183 -0.0589 -0.99 -1.6574 -0.9881 1628717 Maybridge4_004238 NNC(=O)c1csc(Cc2c(Cl)cccc2Cl)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A15 compound treatment 0.285 0.0193 0.28 0.236 -0.00594 -0.1 0.1246 0.4248 3064999 Maybridge4_004239 CCN(CC)c1cnn(c2ccc(cc2)C(F)(F)F)c(=O)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A16 compound treatment 0.272 0.00629 0.09 0.221 -0.0209 -0.35 -0.1849 -0.5098 1426168 Maybridge4_004240 NNC(=O)c1csc(COc2cc(Cl)cc(Cl)c2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A17 compound treatment 0.22 -0.0457 -0.65 0.211 -0.0309 -0.52 -0.8295 -0.9935 1381395 Maybridge4_004241 COC(=O)c1ccc(o1)S(=O)(=O)NCc2ccco2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A18 compound treatment 0.28 0.0143 0.2 0.229 -0.0129 -0.22 -0.0091 -0.0304 3065000 Maybridge4_004242 CC(C)n1c(S)nc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A19 compound treatment 0.209 -0.0567 -0.81 0.211 -0.0309 -0.52 -0.9408 -0.9768 3065124 Maybridge4_004243 CC(C)(C)c1nnc(S)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A20 compound treatment 0.29 0.0243 0.35 0.237 -0.00494 -0.08 0.187 0.5237 1241496 Maybridge4_004244 CC(C)(C)c1ccc(cc1)c2noc(CCn3c(=O)oc4ccccc34)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A21 compound treatment 0.296 0.0303 0.43 0.206 -0.0359 -0.6 -0.1202 -0.1619 3178385 Maybridge4_004245 CC(Oc1ccc(Cl)cc1Cl)/C(=N/O)/N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A22 compound treatment 0.29 0.0243 0.35 0.202 -0.0399 -0.67 -0.2284 -0.3025 3178386 Maybridge4_004246 Cc1cc(no1)c2nnc(o2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A23 mock treatment 0.27 0.00429 0.06 0.258 0.0161 0.27 0.234 0.8463 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 A24 mock treatment 0.213 -0.0527 -0.75 0.222 -0.0199 -0.33 -0.7698 -0.9332 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B01 compound treatment 0.215 -0.0507 -0.73 0.21 -0.0319 -0.54 -0.892 -0.9889 3065125 Maybridge4_004247 Cc1nc(sc1C(=O)Sc2ccc(C)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B02 compound treatment 0.164 -0.102 -1.45 0.139 -0.103 -1.73 -2.2504 -0.9963 3178387 Maybridge4_004248 CCOC(=O)c1cc2c(NCc3ccc(Cl)cc3Cl)nccc2nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B03 compound treatment 0.26 -0.00571 -0.08 0.218 -0.0239 -0.4 -0.3419 -0.8339 3065126 Maybridge4_004249 NNC(=O)c1ccc(Oc2cc(Cl)cc(Cl)c2)o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B04 compound treatment 0.244 -0.0217 -0.31 0.208 -0.0339 -0.57 -0.6224 -0.9593 3178388 Maybridge4_004250 CCOC(=O)c1cc(on1)c2ccnn2S(=O)(=O)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B05 compound treatment 0.276 0.0103 0.15 0.214 -0.0279 -0.47 -0.2275 -0.463 1700962 Maybridge4_004251 COC(=O)c1c(C)nn(C(=O)c2ccc(C)cc2)c1c3cc(C)on3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B06 compound treatment 0.232 -0.0337 -0.48 0.23 -0.0119 -0.2 -0.4827 -0.9243 3178389 Maybridge4_004252 Cc1nc2ccccn2c1c3ccnc(S)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B07 compound treatment 0.268 0.00229 0.03 0.197 -0.0449 -0.75 -0.5102 -0.6758 3065128 Maybridge4_004253 Cc1nc(cs1)c2c(C)onc2C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B08 compound treatment 0.291 0.0253 0.36 0.215 -0.0269 -0.45 -0.064 -0.1105 3178390 Maybridge4_004254 CC(O)c1cc(no1)c2ccc(Cl)cc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B09 compound treatment 0.278 0.0123 0.18 0.204 -0.0379 -0.64 -0.326 -0.4935 3065129 Maybridge4_004255 CN(C)/C=C/C(=O)c1csc(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B10 compound treatment 0.293 0.0273 0.39 0.21 -0.0319 -0.54 -0.1031 -0.1554 3065175 Maybridge4_004256 Cc1onc(c1c2ccnn2C(=O)c3ccc(Cl)cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B11 compound treatment 0.196 -0.0697 -1.0 0.108 -0.134 -2.25 -2.2947 -0.9331 3178391 Maybridge4_004257 Cc1ccc(cc1)C(=O)Sc2ncc(cc2Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B12 compound treatment 0.278 0.0123 0.18 0.212 -0.0299 -0.5 -0.231 -0.434 3065177 Maybridge4_004258 COC(OC)c1nc(SCC#N)c(C#N)cc1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B13 compound treatment 0.336 0.0703 1.01 0.208 -0.0339 -0.57 0.3081 0.2666 3178392 Maybridge4_004259 Cc1nn(C(=O)c2ccc(Cl)cc2)c(C)c1Sc3nnc(n3C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B14 compound treatment 0.314 0.0483 0.69 0.203 -0.0389 -0.65 0.0263 0.0276 3065178 Maybridge4_004260 Cc1nccc(n1)c2cc(no2)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B15 compound treatment 0.353 0.0873 1.25 0.204 -0.0379 -0.64 0.4326 0.3087 3178393 Maybridge4_004261 FC(F)(F)c1ccc(cc1)n2ccc(=O)c(n2)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B16 compound treatment 0.418 0.152 2.18 0.199 -0.0429 -0.72 1.0307 0.4492 3065180 Maybridge4_004262 Cc1noc2ncnc(SCC(=O)Nc3cc(Cl)cc(Cl)c3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B17 compound treatment 0.421 0.155 2.22 0.216 -0.0259 -0.44 1.2628 0.5579 3178394 Maybridge4_004263 Cn1c(SCC(=O)c2ccccc2)nnc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B18 compound treatment 0.448 0.182 2.61 0.255 0.0131 0.22 1.9987 0.7639 1443847 Maybridge4_004264 COc1ccc(cc1)c2csc(n2)c3c(C)noc3N(C(=O)C)C(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B19 compound treatment 0.373 0.107 1.53 0.239 -0.00294 -0.05 1.0502 0.684 3065181 Maybridge4_004265 COCc1nc(SCC(=O)OC)c(C#N)cc1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B20 compound treatment 0.314 0.0483 0.69 0.213 -0.0289 -0.49 0.1449 0.1717 3178395 Maybridge4_004266 Cn1c(SCC(=O)c2ccc(Cl)cc2)nnc1c3ncc(cc3Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B21 compound treatment 0.334 0.0683 0.98 0.315 0.0731 1.23 1.5578 0.9936 3065182 Maybridge4_004267 Cc1ccc(CSc2cnc(C)nc2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B22 compound treatment 0.247 -0.0187 -0.27 0.244 0.00206 0.03 -0.1648 -0.6106 1614331 Maybridge4_004268 CSc1nc(COc2ccc(cc2)C(C)(C)C)nc(c1C#N)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B23 mock treatment 0.244 -0.0217 -0.31 0.266 0.0241 0.4 0.066 0.1294 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 B24 mock treatment 0.229 -0.0367 -0.53 0.226 -0.0159 -0.27 -0.5605 -0.951 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C01 compound treatment 0.171 -0.0947 -1.35 0.179 -0.0629 -1.06 -1.7049 -0.9924 3065184 Maybridge4_004269 COc1cc(/C=C(\C#N)/c2ccc(C)cc2)cc(OC)c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C02 compound treatment 0.257 -0.00871 -0.12 0.186 -0.0559 -0.94 -0.752 -0.794 1173149 Maybridge4_004270 CN(C)C(=O)n1c(SCc2ccccc2)nnc1c3ccc(cc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C03 compound treatment 0.275 0.00929 0.13 0.186 -0.0559 -0.94 -0.57 -0.6011 3065185 Maybridge4_004271 Cc1c(cc(c2ccccc2)n1CCSc3cc(nc4ccccc34)C(F)(F)F)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C04 compound treatment 0.418 0.152 2.18 0.205 -0.0369 -0.62 1.1019 0.4865 3178396 Maybridge4_004272 CN/C(=C(\C(=O)OC)/C(=O)c1ccc(Cl)cc1Cl)/C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C05 compound treatment 0.362 0.0963 1.38 0.268 0.0261 0.44 1.2832 0.888 1218418 Maybridge4_004273 CCOC(=O)c1cc(n(c1C)c2ccc(cc2)N3CCOCC3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C06 compound treatment 0.473 0.207 2.96 0.244 0.00206 0.03 2.121 0.7153 3065186 Maybridge4_004274 CCOC(=O)c1cc(C)nn1C(=O)c2c(F)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C07 compound treatment 0.384 0.118 1.69 0.21 -0.0319 -0.54 0.8173 0.4605 3178397 Maybridge4_004275 CCOC(=O)Cc1csc(n1)c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C08 compound treatment 0.422 0.156 2.24 0.24 -0.00194 -0.03 1.5577 0.6967 3065189 Maybridge4_004276 C/N=c/1\scc(C)n1NC(=O)Nc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C09 compound treatment 0.39 0.124 1.78 0.208 -0.0339 -0.57 0.8543 0.4576 1159039 Maybridge4_004277 CSCCn1c(C)c(cc1c2ccccc2)C(=O)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C10 compound treatment 0.387 0.121 1.73 0.22 -0.0219 -0.37 0.9664 0.5449 3178398 Maybridge4_004278 CN(C)/C=N/c1sc(C)c(C)c1C(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C11 compound treatment 0.346 0.0803 1.15 0.159 -0.0829 -1.39 -0.1723 -0.0955 1508854 Maybridge4_004279 Cc1oc(cc1c2cc(N)n(n2)c3ccc(I)cc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C12 compound treatment 0.368 0.102 1.46 0.252 0.0101 0.17 1.154 0.7835 3178399 Maybridge4_004280 FC(F)(F)c1ccc(CS(=O)(=O)c2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C13 compound treatment 0.414 0.148 2.12 0.229 -0.0129 -0.22 1.3463 0.6314 3065228 Maybridge4_004281 CCOC(=O)c1c(C)n(c(C)c1S(=O)(=O)Nc2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C14 compound treatment 0.351 0.0853 1.22 0.248 0.00606 0.1 0.9345 0.7634 1718696 Maybridge4_004282 NNC(=O)c1csc(CS(=O)(=O)c2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C15 compound treatment 0.473 0.207 2.96 0.292 0.0501 0.84 2.6907 0.8731 3065230 Maybridge4_004283 Clc1ccc(OCc2nc(CSc3cccs3)no2)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C16 compound treatment 0.361 0.0953 1.36 0.245 0.00306 0.05 1.0001 0.7333 3178400 Maybridge4_004284 CCOC(=O)c1csc(n1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C17 compound treatment 0.417 0.151 2.16 0.253 0.0111 0.19 1.6614 0.765 3178401 Maybridge4_004285 OC1(CC(=NN1)/C=C/c2ccc3OCOc3c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C18 compound treatment 0.316 0.0503 0.72 0.211 -0.0309 -0.52 0.1414 0.1594 3065232 Maybridge4_004286 CCn1nc(C)cc1C(=O)Sc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C19 compound treatment 0.358 0.0923 1.32 0.249 0.00706 0.12 1.0172 0.7675 3065234 Maybridge4_004287 CC(C)(C)c1nnc(SCC=C)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C20 compound treatment 0.4 0.134 1.92 0.201 -0.0409 -0.69 0.8723 0.4276 1140041 Maybridge4_004288 CCOC(=O)c1sc(nc1OCc2c(Cl)cccc2Cl)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C21 compound treatment 0.32 0.0543 0.78 0.051 -0.191 -3.2 -1.717 -0.5207 3065235 Maybridge4_004289 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nc(S)n[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C22 compound treatment 0.429 0.163 2.34 0.21 -0.0319 -0.54 1.2725 0.531 3178402 Maybridge4_004290 Oc1nnc(SCc2nnc(o2)c3ccc(Cl)cc3)n1C4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C23 mock treatment 0.244 -0.0217 -0.31 0.206 -0.0359 -0.6 -0.6461 -0.9524 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 C24 mock treatment 0.198 -0.0677 -0.97 0.202 -0.0399 -0.67 -1.1589 -0.9838 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D01 compound treatment 0.226 -0.0397 -0.57 0.225 -0.0169 -0.28 -0.6027 -0.9488 3178403 Maybridge4_004291 Cc1nc(sc1C(=O)Sc2ccc(Cl)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D02 compound treatment 0.216 -0.0497 -0.71 0.211 -0.0309 -0.52 -0.87 -0.9881 3065236 Maybridge4_004292 ON/C=N\c1nonc1c2cccnc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D03 compound treatment 0.387 0.121 1.73 0.197 -0.0449 -0.75 0.6934 0.3665 3178404 Maybridge4_004293 CC(C)(C)c1nnc(o1)c2ccc(Oc3cc(Cl)cc(Cl)c3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D04 compound treatment 0.504 0.238 3.41 0.201 -0.0409 -0.69 1.9242 0.5534 1440627 Maybridge4_004294 CCOC(=O)c1c(C)noc1c2csc(Nc3c(C)cc(C)cc3C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D05 compound treatment 0.506 0.24 3.44 0.186 -0.0559 -0.94 1.7664 0.4958 3178405 Maybridge4_004295 FC(F)(F)Oc1ccc(cc1)c2noc(NC(=O)Nc3cccc(Cl)c3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D06 compound treatment 0.476 0.21 3.01 0.257 0.0151 0.25 2.3056 0.7638 3065237 Maybridge4_004296 CCOC(=O)c1cc(on1)c2ccnn2S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D07 compound treatment 0.43 0.164 2.35 0.298 0.0561 0.94 2.327 0.9193 3178406 Maybridge4_004297 CC(C)(C)C(=O)CSc1nnc(o1)c2cc(OCC(F)(F)F)ccc2OCC(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D08 compound treatment 0.457 0.191 2.74 0.376 0.134 2.25 3.5258 0.9953 1286523 Maybridge4_004298 Clc1cc(Cl)cc(OCc2nc(cs2)c3cc(no3)c4ccccc4)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D09 compound treatment 0.512 0.246 3.52 0.397 0.155 2.6 4.3313 0.9889 3178492 Maybridge4_004299 Cc1cc(no1)c2onc(C)c2C(=O)NC(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D10 compound treatment 0.548 0.282 4.04 0.405 0.163 2.74 4.7903 0.9821 3065285 Maybridge4_004300 Cc1onc(c1c2ccnn2S(=O)(=O)c3ccc(Cl)cc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D11 compound treatment 0.492 0.226 3.24 0.377 0.135 2.27 3.8916 0.9848 3178493 Maybridge4_004301 Cc1ccc(CSc2ncc(cc2Cl)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D12 compound treatment 0.374 0.108 1.55 0.303 0.0611 1.02 1.8199 0.9799 3065286 Maybridge4_004302 Cc1onc(c1c2ccnc(S)n2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D13 compound treatment 0.465 0.199 2.85 0.403 0.161 2.7 3.9271 0.9996 3178494 Maybridge4_004303 Cc1cc(no1)C(=O)NN2C3CSC2CS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D14 compound treatment 0.396 0.13 1.86 0.378 0.136 2.28 2.9325 0.9949 3178495 Maybridge4_004304 CC(=O)Nc1nccc(n1)c2cc(no2)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D15 compound treatment 0.449 0.183 2.62 0.397 0.155 2.6 3.6941 1.0 3065290 Maybridge4_004305 CN(C)C(=O)Oc1nc(nc(C)c1Oc2cccc(c2)C(F)(F)F)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D16 compound treatment 0.457 0.191 2.74 0.404 0.162 2.72 3.8581 1.0 3178496 Maybridge4_004306 Cc1noc2ncnc(SCc3ccc(Cl)cc3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D17 compound treatment 0.538 0.272 3.89 0.392 0.15 2.52 4.5349 0.9777 3065291 Maybridge4_004307 Cn1ccnc1SCC(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D18 compound treatment 0.483 0.217 3.11 0.38 0.138 2.32 3.8362 0.9895 1501067 Maybridge4_004308 CCOC(=O)c1cnc(COc2ccc(cc2)C(C)(C)C)nc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D19 compound treatment 0.423 0.157 2.25 0.329 0.0871 1.46 2.6241 0.9782 3065292 Maybridge4_004309 Cc1c(Sc2ccc(Cl)cc2)cnn1C(=O)Nc3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D20 compound treatment 0.423 0.157 2.25 0.331 0.0891 1.49 2.6478 0.9803 3178497 Maybridge4_004310 FC(F)(F)c1cnc(c2nnc(SCC#N)n2c3ccc(Cl)cc3)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D21 compound treatment 0.392 0.126 1.81 0.285 0.0431 0.72 1.7884 0.9192 3178498 Maybridge4_004311 Cc1ccc(CSc2nc(C)c(Oc3cccc(c3)C(F)(F)F)c(=O)n2C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D22 compound treatment 0.557 0.291 4.17 0.277 0.0351 0.59 3.3623 0.7991 3065294 Maybridge4_004312 FC(F)(F)C1CCN(CC1)C(=O)Nc2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D23 mock treatment 0.295 0.0293 0.42 0.286 0.0441 0.74 0.8191 0.9638 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 D24 mock treatment 0.241 -0.0247 -0.35 0.206 -0.0359 -0.6 -0.6765 -0.9676 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E01 compound treatment 0.232 -0.0337 -0.48 0.21 -0.0319 -0.54 -0.72 -0.9986 3065295 Maybridge4_004313 CSc1scc(N)c1S(=O)(=O)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E02 compound treatment 0.225 -0.0407 -0.58 0.204 -0.0379 -0.64 -0.862 -0.999 3178499 Maybridge4_004314 Cc1cc(nn1C)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E03 compound treatment 0.316 0.0503 0.72 0.194 -0.0479 -0.8 -0.0603 -0.0559 3178500 Maybridge4_004315 Cc1c(cc(c2ccccc2)n1CCSCc3c(F)cccc3Cl)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E04 compound treatment 0.474 0.208 2.98 0.232 -0.00994 -0.17 1.9887 0.6665 3065296 Maybridge4_004316 C(Oc1ccc(cc1)C2SCCS2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E05 compound treatment 0.459 0.193 2.76 0.214 -0.0279 -0.47 1.6234 0.5789 1532983 Maybridge4_004317 Clc1ccc(cc1Cl)c2csc(CC#N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E06 compound treatment 0.524 0.258 3.69 0.334 0.0921 1.55 3.705 0.9252 3178501 Maybridge4_004318 Cc1cc(CSc2cc(C)c(Cl)cc2C)no1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E07 compound treatment 0.429 0.163 2.34 0.39 0.148 2.49 3.4087 0.9995 3178502 Maybridge4_004319 CC(C)OC(=O)Cc1csc(n1)c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E08 compound treatment 0.528 0.262 3.75 0.43 0.188 3.16 4.8848 0.9963 3065298 Maybridge4_004320 C/N=c/1\scc(C)n1\N=C\c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E09 compound treatment 0.472 0.206 2.95 0.354 0.112 1.88 3.4164 0.9764 1516019 Maybridge4_004321 Cc1noc(C)c1c2nc(no2)c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E10 compound treatment 0.5 0.234 3.35 0.42 0.178 2.99 4.4829 0.9984 1538780 Maybridge4_004322 NNC(=O)Cc1csc(n1)c2cccc(c2)n3cccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E11 compound treatment 0.288 0.0223 0.32 0.453 0.211 3.54 2.7303 0.7676 1280770 Maybridge4_004323 Cc1oc(cc1C(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E12 compound treatment 0.529 0.263 3.77 0.405 0.163 2.74 4.5982 0.9877 3065299 Maybridge4_004324 Clc1ccc(cc1)S(=O)(=O)Cc2nc(CSc3ccccn3)cs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E13 compound treatment 0.537 0.271 3.88 0.431 0.189 3.17 4.9877 0.995 1082796 Maybridge4_004325 CC(C)(C)C(=O)CN1C(=O)c2ccccc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E14 compound treatment 0.4 0.134 1.92 0.407 0.165 2.77 3.3172 0.984 1345163 Maybridge4_004326 Clc1cccc(Cl)c1Cc2nc(NC(=O)NN3CCOCC3)cs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E15 compound treatment 0.486 0.22 3.15 0.395 0.153 2.57 4.0446 0.9949 3065350 Maybridge4_004327 FC(F)(F)Oc1ccc(/C=C/C(=O)Nc2ccc3[nH]cc(C#N)c3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E16 compound treatment 0.481 0.215 3.08 0.413 0.171 2.87 4.2076 0.9994 3178503 Maybridge4_004328 NNC(=O)c1csc(n1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E17 compound treatment 0.196 -0.0697 -1.0 0.138 -0.104 -1.74 -1.9386 -0.9648 3178504 Maybridge4_004329 CC1=CSC2SC(=C(C)C21)C3=NNC(O)(C3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E18 compound treatment 0.282 0.0163 0.23 0.271 0.0291 0.49 0.5096 0.9428 3065351 Maybridge4_004330 Cc1nc(COc2cccc(Cl)c2)sc1c3ccnn3C(=O)C=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E19 compound treatment 0.528 0.262 3.75 0.41 0.168 2.82 4.6474 0.9901 3178505 Maybridge4_004331 CC(C)(C)c1nc2scc(c3ccc(Cl)cc3)n2n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E20 compound treatment 0.455 0.189 2.71 0.285 0.0431 0.72 2.4255 0.8656 1595891 Maybridge4_004332 Clc1ccc(SC(=O)CCn2c(=O)oc3ccccc23)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E21 compound treatment 0.42 0.154 2.21 0.359 0.117 1.96 2.9498 0.9983 3178506 Maybridge4_004333 NNC(=O)c1nc(no1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E22 compound treatment 0.484 0.218 3.12 0.202 -0.0399 -0.67 1.7338 0.5429 3065354 Maybridge4_004334 Cc1nc(cs1)C(=S)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E23 mock treatment 0.343 0.0773 1.11 0.201 -0.0409 -0.69 0.2958 0.2273 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 E24 mock treatment 0.241 -0.0247 -0.35 0.19 -0.0519 -0.87 -0.8664 -0.921 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F01 compound treatment 0.218 -0.0477 -0.68 0.212 -0.0299 -0.5 -0.8379 -0.9887 1669430 Maybridge4_004335 Cc1c(C(=O)Oc2ccc(Cl)cc2)n(C)oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F02 compound treatment 0.219 -0.0467 -0.67 0.19 -0.0519 -0.87 -1.0889 -0.9914 1470635 Maybridge4_004336 CCOC(=O)c1cc(on1)c2csc(CS(=O)(=O)C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F03 compound treatment 0.476 0.21 3.01 0.209 -0.0329 -0.55 1.736 0.5676 3178507 Maybridge4_004337 FC(F)(F)c1ccnc(Oc2ccc(cc2)C3=NCCS3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F04 compound treatment 0.531 0.265 3.79 0.196 -0.0459 -0.77 2.138 0.5521 3065356 Maybridge4_004338 Cc1n[nH]c(=O)c2nc(sc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F05 compound treatment 0.522 0.256 3.67 0.267 0.0251 0.42 2.8896 0.7831 3178508 Maybridge4_004339 FC(F)(F)Oc1ccc(cc1)c2noc(NC(=O)NN3CCCCC3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F06 compound treatment 0.513 0.247 3.54 0.361 0.119 2.0 3.9141 0.9635 3178509 Maybridge4_004340 Cc1nc2ccccn2c1c3ccnc(SCC(=O)c4ccc(Cl)cc4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F07 compound treatment 0.565 0.299 4.28 0.453 0.211 3.54 5.532 0.9956 3065357 Maybridge4_004341 Cc1nnsc1c2onc(C)c2C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F08 compound treatment 0.53 0.264 3.78 0.418 0.176 2.96 4.7626 0.9926 3065359 Maybridge4_004342 Cc1nc2ccccn2c1c3ccnn3C(=O)c4ccc(cc4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F09 compound treatment 0.444 0.178 2.55 0.436 0.194 3.26 4.1064 0.9927 1733300 Maybridge4_004343 Sc1nccc(n1)c2csc(COc3ccccc3Cl)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F10 compound treatment 0.481 0.215 3.08 0.441 0.199 3.34 4.5399 0.9992 3178510 Maybridge4_004344 Cc1onc(c1c2csc(Nc3ccccc3Cl)n2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F11 compound treatment 0.572 0.306 4.38 0.434 0.192 3.22 5.3773 0.9886 3178511 Maybridge4_004345 COC(=O)c1sccc1NC(=O)C2CCCS2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F12 compound treatment 0.53 0.264 3.78 0.489 0.247 4.15 5.6052 0.9989 3065409 Maybridge4_004346 COC(OC)c1c(cnn1C(=O)Nc2ccccc2)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F13 compound treatment 0.538 0.272 3.89 0.429 0.187 3.14 4.974 0.9943 3178512 Maybridge4_004347 CCOC(=O)c1nn(cc(Sc2nnc(n2C)C(F)(F)F)c1=O)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F14 compound treatment 0.451 0.185 2.65 0.413 0.171 2.87 3.9042 0.9992 3065410 Maybridge4_004348 Cc1cc(no1)c2c(C(=O)Sc3ccccc3)c(C)nn2c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F15 compound treatment 0.566 0.3 4.3 0.395 0.153 2.57 4.8537 0.9698 3178513 Maybridge4_004349 CN(C)C(=O)Oc1nc(nc(C)c1Oc2ccc(Cl)cc2Cl)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F16 compound treatment 0.489 0.223 3.19 0.456 0.214 3.59 4.7989 0.9983 3065413 Maybridge4_004350 Cc1noc2ncnc(SCc3ccc(cc3)C(F)(F)F)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F17 compound treatment 0.505 0.239 3.42 0.389 0.147 2.47 4.1655 0.9871 1122678 Maybridge4_004351 Cn1ccnc1Sc2cnc(SCc3ccc(Cl)cc3)nc2c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F18 compound treatment 0.491 0.225 3.22 0.427 0.185 3.11 4.4749 0.9998 1056664 Maybridge4_004352 NC(=O)COc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F19 compound treatment 0.504 0.238 3.41 0.413 0.171 2.87 4.4403 0.9964 3178514 Maybridge4_004353 COC(OC)c1ccc(C#N)c(SCc2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F20 compound treatment 0.506 0.24 3.44 0.439 0.197 3.31 4.7691 0.9998 3065416 Maybridge4_004354 Cc1ccc(/N=C/c2c(Sc3ccc(Cl)cc3)nc4sccn24)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F21 compound treatment 0.318 0.0523 0.75 0.264 0.0221 0.37 0.7907 0.9474 3178515 Maybridge4_004355 COc1ccc(C/N=C/c2ccnc(SCc3ccc(Cl)cc3Cl)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F22 compound treatment 0.514 0.248 3.55 0.277 0.0351 0.59 2.9273 0.8132 1543403 Maybridge4_004356 CC(C)(C)c1ccc(OCc2ncc(c(N)n2)S(=O)(=O)c3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F23 mock treatment 0.433 0.167 2.39 0.255 0.0131 0.22 1.847 0.7687 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 F24 mock treatment 0.205 -0.0607 -0.87 0.236 -0.00594 -0.1 -0.6845 -0.7831 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G01 compound treatment 0.257 -0.00871 -0.12 0.238 -0.00394 -0.07 -0.1349 -0.956 3065419 Maybridge4_004357 CCOC(=O)c1cc(oc1C(F)(F)F)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G02 compound treatment 0.257 -0.00871 -0.12 0.232 -0.00994 -0.17 -0.2061 -0.9897 3178592 Maybridge4_004358 NNC(=O)Cc1csc2nc(nn12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G03 compound treatment 0.371 0.105 1.51 0.226 -0.0159 -0.27 0.8757 0.5725 1715416 Maybridge4_004359 CCOC(=O)c1cc(c2ccccc2)n(CCNC(=O)OC(C)(C)C)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G04 compound treatment 0.506 0.24 3.44 0.221 -0.0209 -0.35 2.1818 0.6315 3178593 Maybridge4_004360 Cc1n[nH]c(c2cccs2)c1C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G05 compound treatment 0.517 0.251 3.59 0.321 0.0791 1.33 3.4799 0.9082 1728275 Maybridge4_004361 Cc1ccc(cc1)c2csc(CS(=O)(=O)C(C)(C)C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G06 compound treatment 0.514 0.248 3.55 0.419 0.177 2.97 4.6126 0.9961 3178594 Maybridge4_004362 NNC(=O)c1cc(CSc2ccc(Cl)cc2)on1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G07 compound treatment 0.525 0.259 3.71 0.448 0.206 3.46 5.068 0.9994 1526465 Maybridge4_004363 CC(C)(C)S(=O)(=O)Cc1nc(cs1)c2cccc(F)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G08 compound treatment 0.375 0.109 1.56 0.28 0.0381 0.64 1.5571 0.9221 3065422 Maybridge4_004364 Clc1ccc(CSc2ncc([nH]2)c3ccc(Cl)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G09 compound treatment 0.537 0.271 3.88 0.422 0.18 3.02 4.8808 0.9924 1241834 Maybridge4_004365 Fc1ccc(CS(=O)(=O)Cc2noc(n2)c3ccno3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G10 compound treatment 0.422 0.156 2.24 0.483 0.241 4.05 4.4417 0.9609 3064623 Maybridge4_004366 Cc1ccc(cc1)C(=O)CSc2nc(n[nH]2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G11 compound treatment 0.395 0.129 1.85 0.482 0.24 4.03 4.1567 0.9376 3178595 Maybridge4_004367 Fc1ccc2[nH]c3CN(CCc3c2c1)S(=O)(=O)c4ccc(s4)c5cc(on5)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G12 compound treatment 0.334 0.0683 0.98 0.256 0.0141 0.24 0.8576 0.8534 3064626 Maybridge4_004368 CCOC(=O)c1sc(SCC(=O)c2ccc(Cl)cc2Cl)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G13 compound treatment 0.555 0.289 4.14 0.448 0.206 3.46 5.3715 0.996 1519116 Maybridge4_004369 CCOC(=O)c1c(C)n(c(c1S(=O)(=O)NCc2ccccc2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G14 compound treatment 0.528 0.262 3.75 0.369 0.127 2.13 4.1608 0.9642 3064627 Maybridge4_004370 N/C(=N\O)/CS(=O)(=O)Cc1ccc(F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G15 compound treatment 0.323 0.0573 0.82 0.484 0.242 4.06 3.4522 0.8329 3178596 Maybridge4_004371 OC1(CC(=NN1)C2(CC3CC4CC(C3)C2)C4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G16 compound treatment 0.437 0.171 2.45 0.456 0.214 3.59 4.2729 0.9826 3064629 Maybridge4_004372 Cc1nc(CSc2nnc([nH]2)C(C)(C)C)cs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G17 compound treatment 0.533 0.267 3.82 0.469 0.227 3.81 5.3982 1.0 3178597 Maybridge4_004373 CN1N=C(CC1(O)C(F)(F)F)c2coc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G18 compound treatment 0.41 0.144 2.06 0.47 0.228 3.83 4.166 0.958 1698546 Maybridge4_004374 CC(C)n1c(SCC(=O)O)nc2cc(Cl)ccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G19 compound treatment 0.418 0.152 2.18 0.348 0.106 1.78 2.799 0.995 2121946 Maybridge4_004375 FC(F)(F)c1n[nH]c(SCc2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G20 compound treatment 0.403 0.137 1.96 0.387 0.145 2.43 3.1102 0.9943 3064630 Maybridge4_004376 FC(F)(F)c1ccc(SC(=O)CCn2c(=O)oc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G21 compound treatment 0.57 0.304 4.35 0.323 0.0811 1.36 4.0397 0.8859 3178598 Maybridge4_004377 CSc1nc(nn1C(=O)N(C)C)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G22 compound treatment 0.511 0.245 3.51 0.274 0.0321 0.54 2.8614 0.8061 1190557 Maybridge4_004378 Fc1ccc(cc1)n2ccc(=O)c(n2)c3cc[nH]n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G23 mock treatment 0.319 0.0533 0.76 0.221 -0.0209 -0.35 0.2905 0.3461 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 G24 mock treatment 0.216 -0.0497 -0.71 0.189 -0.0529 -0.89 -1.1311 -0.9939 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H01 compound treatment 0.276 0.0103 0.15 0.226 -0.0159 -0.27 -0.0851 -0.2788 3178599 Maybridge4_004379 FC(F)(F)c1ccc(Cn2c(=O)oc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H02 compound treatment 0.226 -0.0397 -0.57 0.191 -0.0509 -0.85 -1.0062 -0.9803 3178600 Maybridge4_004380 FC(F)(F)c1ccc(cc1)c2nc(cs2)C(=O)/C=C/N3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H03 compound treatment 0.507 0.241 3.45 0.207 -0.0349 -0.59 2.0258 0.5787 1643215 Maybridge4_004381 Cc1cc(C(=O)NN)n(n1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H04 compound treatment 0.483 0.217 3.11 0.232 -0.00994 -0.17 2.0797 0.6682 3064634 Maybridge4_004382 Cc1nc2c(=O)n(nc(C)c2s1)c3cc(ccc3Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H05 compound treatment 0.54 0.274 3.92 0.388 0.146 2.45 4.5077 0.9744 3178601 Maybridge4_004383 Cc1nc(nc(O)c1Cl)c2ccccc2OC(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H06 compound treatment 0.457 0.191 2.74 0.4 0.158 2.65 3.8106 0.9999 3178602 Maybridge4_004384 Cc1nc2ccccn2c1c3ccnc(SCC(=O)c4cccc(c4)C(F)(F)F)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H07 compound treatment 0.512 0.246 3.52 0.374 0.132 2.22 4.0583 0.9751 3064670 Maybridge4_004385 CC(C)(C)c1csc(n1)c2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H08 compound treatment 0.567 0.301 4.31 0.539 0.297 4.99 6.5728 0.9974 1738969 Maybridge4_004386 Cc1nc2ccccn2c1c3ccnn3C(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H09 compound treatment 0.46 0.194 2.78 0.464 0.222 3.73 4.6005 0.9895 3064672 Maybridge4_004387 CCOC(=O)c1c(Sc2ccccc2)cnn1C(=O)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H10 compound treatment 0.528 0.262 3.75 0.418 0.176 2.96 4.7423 0.993 3178603 Maybridge4_004388 O=C(c1ccno1)n2nccc2c3cc(no3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H11 compound treatment 0.544 0.278 3.98 0.544 0.302 5.07 6.3995 0.9928 3064674 Maybridge4_004389 CCOC(=O)c1[nH]ncc1Sc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H12 compound treatment 0.57 0.304 4.35 0.474 0.232 3.89 5.8318 0.9985 3178604 Maybridge4_004390 CCOC(=O)c1cc(nn1C(=O)C)c2ccc(Cl)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H13 compound treatment 0.584 0.318 4.55 0.54 0.298 5.0 6.7566 0.9989 1154209 Maybridge4_004391 CCOC(=O)c1nn(cc(Sc2ccc(Cl)cc2)c1=O)c3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H14 compound treatment 0.504 0.238 3.41 0.511 0.269 4.52 5.6033 0.9904 3064675 Maybridge4_004392 Cc1cc(no1)c2nc(cs2)c3ccnn3C(=O)Nc4cccc(Cl)c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H15 compound treatment 0.422 0.156 2.24 0.485 0.243 4.08 4.4654 0.9599 1612205 Maybridge4_004393 Cc1nc(C)c(Oc2ccc(Cl)cc2Cl)c(n1)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H16 compound treatment 0.354 0.0883 1.26 0.378 0.136 2.28 2.5077 0.961 3064677 Maybridge4_004394 Cc1nc(nc(Sc2ccccc2Cl)c1Oc3ccccc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H17 compound treatment 0.471 0.205 2.94 0.418 0.176 2.96 4.1658 1.0 1277240 Maybridge4_004395 Cn1ccnc1Sc2cnc(SCC(=O)c3ccc(Cl)cc3)nc2c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H18 compound treatment 0.565 0.299 4.28 0.525 0.283 4.75 6.3865 0.9986 3178605 Maybridge4_004396 COC(OC)c1nc(SCC(=O)Nc2ccc(cc2)C(C)C)ncc1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H19 compound treatment 0.587 0.321 4.6 0.487 0.245 4.11 6.158 0.9985 1575021 Maybridge4_004397 Cc1onc2c(=O)n(nc(C)c12)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H20 compound treatment 0.493 0.227 3.25 0.441 0.199 3.34 4.6613 0.9999 1613403 Maybridge4_004398 CCOC(=O)c1cnc(nc1Nc2ccc(C)cc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H21 compound treatment 0.428 0.162 2.32 0.256 0.0141 0.24 1.8083 0.775 3178606 Maybridge4_004399 COc1ccccc1CC/N=C/c2ccnc(SCc3ccc(Cl)cc3Cl)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H22 compound treatment 0.565 0.299 4.28 0.369 0.127 2.13 4.535 0.9482 3064678 Maybridge4_004400 FC(F)(F)COc1ccc(cn1)c2nc(cs2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H23 mock treatment 0.459 0.193 2.76 0.249 0.00706 0.12 2.0388 0.7367 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 H24 mock treatment 0.26 -0.00571 -0.08 0.202 -0.0399 -0.67 -0.5318 -0.7875 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I01 compound treatment 0.132 -0.134 -1.91 0.166 -0.0759 -1.27 -2.2536 -0.9805 1124762 Maybridge4_004401 Cc1oc(cc1COC(=O)Nc2ccccc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I02 compound treatment 0.253 -0.0127 -0.18 0.224 -0.0179 -0.3 -0.3415 -0.9709 3064679 Maybridge4_004402 Oc1nnc(SCC=C)n1c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I03 compound treatment 0.482 0.216 3.09 0.221 -0.0209 -0.35 1.9391 0.6228 3178607 Maybridge4_004403 Cc1ccc(cc1)c2csc(n2)c3ccc(cc3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I04 compound treatment 0.535 0.269 3.85 0.276 0.0341 0.57 3.1279 0.8033 3178608 Maybridge4_004404 O=C(Oc1ccc2ccccc2c1C3SCCS3)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I05 compound treatment 0.451 0.185 2.65 0.455 0.213 3.58 4.4027 0.9891 3064680 Maybridge4_004405 Fc1cccc(c1)c2csc(COc3ccccc3Cl)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I06 compound treatment 0.51 0.244 3.49 0.367 0.125 2.1 3.955 0.9703 3064719 Maybridge4_004406 CCOC(=O)c1cc(COc2c(Cl)cccc2Cl)on1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I07 compound treatment 0.493 0.227 3.25 0.354 0.112 1.88 3.6288 0.9662 1539274 Maybridge4_004407 COc1ccc(cc1OC)c2nc(CS(=O)(=O)c3ccc(F)cc3)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I08 compound treatment 0.533 0.267 3.82 0.355 0.113 1.9 4.0452 0.9478 3064721 Maybridge4_004408 COC(=O)c1c(C)n[nH]c1c2snnc2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I09 compound treatment 0.471 0.205 2.94 0.443 0.201 3.37 4.4625 0.9976 3178609 Maybridge4_004409 Cc1c(cc(c2ccccc2)n1CCSCc3c(F)cccc3Cl)C(=O)NCc4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I10 compound treatment 0.422 0.156 2.24 0.479 0.237 3.98 4.3942 0.9628 3064722 Maybridge4_004410 FC(F)(F)c1ccccc1c2ncc(o2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I11 compound treatment 0.438 0.172 2.46 0.402 0.16 2.69 3.6422 0.9991 3178610 Maybridge4_004411 COC(=O)C1SCCN1S(=O)(=O)c2ccc(s2)c3cc(on3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I12 compound treatment 0.499 0.233 3.34 0.376 0.134 2.25 3.9506 0.9816 3064724 Maybridge4_004412 CCOC(=O)c1sc(COc2ccc(cc2)C3SCCS3)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I13 compound treatment 0.473 0.207 2.96 0.438 0.196 3.29 4.4234 0.9986 3178611 Maybridge4_004413 CCOC(=O)c1c(C)oc(c1S(=O)(=O)NCc2ccccc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I14 compound treatment 0.421 0.155 2.22 0.426 0.184 3.09 3.7551 0.9869 1359873 Maybridge4_004414 CCOC(=O)c1sc(COc2ccc(cc2)C(C)(C)C)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I15 compound treatment 0.531 0.265 3.79 0.516 0.274 4.6 5.9358 0.9954 1719811 Maybridge4_004415 COC(=O)c1cc(oc1C)S(=O)(=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I16 compound treatment 0.524 0.258 3.69 0.351 0.109 1.83 3.9067 0.9475 3064726 Maybridge4_004416 Fc1ccc(NC(=O)Nc2csc(n2)c3cccs3)c(F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I17 compound treatment 0.516 0.25 3.58 0.436 0.194 3.26 4.8346 0.9989 3178696 Maybridge4_004417 CCOC(=O)c1cc(C)nc(Sc2ccccn2)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I18 compound treatment 0.48 0.214 3.07 0.471 0.229 3.84 4.8859 0.9937 1015446 Maybridge4_004418 NNS(=O)(=O)c1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I19 compound treatment 0.513 0.247 3.54 0.438 0.196 3.29 4.828 0.9993 3178697 Maybridge4_004419 CSc1nnc(c2ccc(cc2)C(C)(C)C)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I20 compound treatment 0.54 0.274 3.92 0.444 0.202 3.39 5.1723 0.9974 3064729 Maybridge4_004420 CC(C)n1c(SCC(=O)c2ccc(C)cc2)nc3cc(ccc13)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I21 compound treatment 0.534 0.268 3.84 0.394 0.152 2.55 4.5182 0.9804 3178698 Maybridge4_004421 CSc1n[nH]c(=O)n1C2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I22 compound treatment 0.502 0.236 3.38 0.306 0.0641 1.08 3.1501 0.8882 1629116 Maybridge4_004422 Fc1ccc(cc1)n2ccc(=O)c(n2)c3ccnc(S)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I23 mock treatment 0.346 0.0803 1.15 0.231 -0.0109 -0.18 0.6822 0.5866 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 I24 mock treatment 0.26 -0.00571 -0.08 0.216 -0.0259 -0.44 -0.3656 -0.8254 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J01 compound treatment 0.223 -0.0427 -0.61 0.255 0.0131 0.22 -0.277 -0.4267 3064730 Maybridge4_004423 Cc1cc(C)c(C#N)c(SCc2nc(no2)c3ccc(OC(F)(F)F)cc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J02 compound treatment 0.262 -0.00371 -0.05 0.212 -0.0299 -0.5 -0.3929 -0.7775 3178699 Maybridge4_004424 COC(=O)c1noc(C)c1C(=O)/C=C/N2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J03 compound treatment 0.425 0.159 2.28 0.206 -0.0359 -0.6 1.1845 0.5026 1578491 Maybridge4_004425 CC(C)(C)c1cc(no1)C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J04 compound treatment 0.526 0.26 3.72 0.217 -0.0249 -0.42 2.3366 0.6237 1270914 Maybridge4_004426 Cc1cc(no1)c2nc(cs2)C(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J05 compound treatment 0.369 0.103 1.48 0.308 0.0661 1.11 1.8287 0.99 1517245 Maybridge4_004427 CN(C)C(=O)c1noc(C)c1c2cc[nH]c(=S)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J06 compound treatment 0.526 0.26 3.72 0.419 0.177 2.97 4.734 0.9938 1241417 Maybridge4_004428 CC(C)c1ccc(NC(=O)CSc2nccc(n2)c3c(C)nc4ccccn34)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J07 compound treatment 0.431 0.165 2.36 0.351 0.109 1.83 2.9661 0.992 3064781 Maybridge4_004429 FC(F)(F)Oc1ccccc1c2nnc(o2)c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J08 compound treatment 0.504 0.238 3.41 0.375 0.133 2.23 3.9893 0.979 1319855 Maybridge4_004430 Cc1nc2ccccn2c1c3ccnn3C(=O)c4ccno4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J09 compound treatment 0.52 0.254 3.64 0.503 0.261 4.38 5.6702 0.9957 3178700 Maybridge4_004431 Clc1ccccc1OCc2nc(cs2)c3ccnc(SCC(=O)c4ccccc4)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J10 compound treatment 0.339 0.0733 1.05 0.375 0.133 2.23 2.3204 0.9405 3178701 Maybridge4_004432 FC(F)(F)c1ccc(cc1)S(=O)(=O)n2nccc2c3cc(no3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J11 compound treatment 0.398 0.132 1.89 0.473 0.231 3.88 4.0802 0.9456 3064782 Maybridge4_004433 FC(F)(F)c1cccnc1SCc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J12 compound treatment 0.556 0.29 4.15 0.508 0.266 4.47 6.0937 0.9993 1133437 Maybridge4_004434 COC(OC)c1nc2sc(C(=O)OC)c(N)c2cc1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J13 compound treatment 0.489 0.223 3.19 0.524 0.282 4.73 5.6059 0.9816 3178702 Maybridge4_004435 CN(C)/C=C(\Sc1ccc(cn1)C(F)(F)F)/C(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J14 compound treatment 0.574 0.308 4.41 0.421 0.179 3.01 5.2432 0.9825 3178703 Maybridge4_004436 Cc1cc(no1)c2nc(cs2)c3ccnn3S(=O)(=O)c4cccc(c4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J15 compound treatment 0.542 0.276 3.95 0.505 0.263 4.42 5.9165 0.9985 3064785 Maybridge4_004437 Cc1nc(C)c(Oc2ccc(Cl)cc2Cl)c(O)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J16 compound treatment 0.447 0.181 2.59 0.498 0.256 4.3 4.8725 0.9707 3064786 Maybridge4_004438 COC(=O)c1c(C)nn(c1c2snnc2C)c3ccc(OC(F)(F)F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J17 compound treatment 0.409 0.143 2.05 0.479 0.237 3.98 4.2627 0.9524 3178704 Maybridge4_004439 Cc1cc(no1)c2noc(n2)c3cc(C)on3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J18 compound treatment 0.482 0.216 3.09 0.502 0.26 4.36 5.274 0.9858 3064787 Maybridge4_004440 CSc1[nH]c(=O)[nH]c(=O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J19 compound treatment 0.411 0.145 2.08 0.455 0.213 3.58 3.9981 0.9667 3178705 Maybridge4_004441 O/N=C/c1ccnc(SCc2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J20 compound treatment 0.566 0.3 4.3 0.485 0.243 4.08 5.9218 0.9997 1443040 Maybridge4_004442 CCOC(=O)c1cnc(nc1Nc2ccc(Cl)cc2)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J21 compound treatment 0.414 0.148 2.12 0.442 0.2 3.36 3.8742 0.9755 1496600 Maybridge4_004443 CN(C)C(=O)Oc1nc(NC(=O)C)nc(C)c1Oc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J22 compound treatment 0.544 0.278 3.98 0.316 0.0741 1.24 3.6936 0.8857 1705322 Maybridge4_004444 Cc1nc(COc2ccc(cc2)C(C)(C)C)ncc1S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J23 mock treatment 0.406 0.14 2.01 0.259 0.0171 0.29 1.6214 0.7999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 J24 mock treatment 0.216 -0.0497 -0.71 0.231 -0.0109 -0.18 -0.6326 -0.8614 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K01 compound treatment 0.141 -0.125 -1.78 0.177 -0.0649 -1.09 -2.0321 -0.9721 3064790 Maybridge4_004445 FC(F)(F)c1oc(cc1COC(=O)Nc2ccccc2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K02 compound treatment 0.252 -0.0137 -0.2 0.205 -0.0369 -0.62 -0.5771 -0.8875 3178706 Maybridge4_004446 CSc1nnc(c2ccc(cc2)C(C)(C)C)n1Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K03 compound treatment 0.579 0.313 4.48 0.242 6.25E-5 0.0 3.1694 0.7073 3064791 Maybridge4_004447 FC(F)(F)c1ccc(cc1)c2nc(cs2)c3ccc(C#N)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K04 compound treatment 0.507 0.241 3.45 0.269 0.0271 0.45 2.7616 0.7933 3065620 Maybridge4_004448 CC(C)(C)c1nnc(SCc2nc(no2)c3cccc(c3)n4cccc4)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K05 compound treatment 0.54 0.274 3.92 0.433 0.191 3.21 5.0417 0.995 3065621 Maybridge4_004449 FC(F)(F)c1ccc(cc1)c2csc(CS(=O)(=O)Cc3cccc(c3)C(F)(F)F)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K06 compound treatment 0.351 0.0853 1.22 0.455 0.213 3.58 3.3912 0.8975 3065622 Maybridge4_004450 NNC(=O)c1cc(COc2c(Cl)cccc2Cl)on1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K07 compound treatment 0.305 0.0393 0.56 0.294 0.0521 0.87 1.0152 0.9772 1292280 Maybridge4_004451 CC1(C)CCC(C)(C)c2cc(ccc21)c3csc(CC#N)n3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K08 compound treatment 0.382 0.116 1.66 0.5 0.258 4.33 4.2388 0.9136 3065623 Maybridge4_004452 COC(=O)c1c(C)nn(C(=O)c2cccs2)c1c3snnc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K09 compound treatment 0.495 0.229 3.28 0.424 0.182 3.06 4.4798 0.9994 3065624 Maybridge4_004453 Cc1ccc(NC(=O)c2cc3cc(OC(F)(F)F)ccc3[nH]2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K10 compound treatment 0.441 0.175 2.51 0.317 0.0751 1.26 2.6637 0.9493 3065625 Maybridge4_004454 Clc1cc(Cl)cc(OCc2nn[nH]n2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K11 compound treatment 0.514 0.248 3.55 0.503 0.261 4.38 5.6095 0.9946 3178707 Maybridge4_004455 CC1(C)C(NS(=O)(=O)c2ccc(s2)c3cc(on3)C(F)(F)F)[C@@]4(C)CCC1C4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K12 compound treatment 0.451 0.185 2.65 0.449 0.207 3.48 4.3315 0.9911 3065626 Maybridge4_004456 Oc1nnc(S)n1Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K13 compound treatment 0.547 0.281 4.02 0.468 0.226 3.79 5.5279 0.9996 1404401 Maybridge4_004457 Cc1cc(C)c2cc([nH]c2c1)C(=O)Nc3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K14 compound treatment 0.207 -0.0587 -0.84 0.355 0.113 1.9 0.748 0.3604 1365668 Maybridge4_004458 Cc1nc(COc2ccc(cc2)C(C)(C)C)sc1C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K15 compound treatment 0.12 -0.146 -2.08 0.286 0.0441 0.74 -0.9508 -0.4299 3065627 Maybridge4_004459 Cc1c(sc2ccccc12)C3=NNC(O)(C3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K16 compound treatment 0.414 0.148 2.12 0.311 0.0691 1.16 2.3194 0.9596 1324032 Maybridge4_004460 NC(=S)CS(=O)(=O)c1ccccn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K17 compound treatment 0.543 0.277 3.97 0.444 0.202 3.39 5.2026 0.997 1539758 Maybridge4_004461 CN(C)C(=O)Nc1c(C)onc1c2c(Cl)cccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K18 compound treatment 0.44 0.174 2.49 0.45 0.208 3.49 4.2321 0.9863 3065628 Maybridge4_004462 CCOC(=O)CSc1nc2cc(Cl)c(Cl)cc2n1CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K19 compound treatment 0.42 0.154 2.21 0.447 0.205 3.44 3.9942 0.9769 1230780 Maybridge4_004463 Cc1cc(NC(=O)NN2CCOCC2)nn1c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K20 compound treatment 0.498 0.232 3.32 0.363 0.121 2.03 3.7862 0.9722 3065629 Maybridge4_004464 CCOC(=O)c1sc(nc1OC(=O)c2ccc(cc2)C(F)(F)F)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K21 compound treatment 0.518 0.252 3.61 0.432 0.19 3.19 4.8074 0.9981 3178708 Maybridge4_004465 Clc1cccc(c1)n2c(SCC=C)n[nH]c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K22 compound treatment 0.483 0.217 3.11 0.315 0.0731 1.23 3.0648 0.9173 3065630 Maybridge4_004466 NNC(=O)Cc1cc(Br)sc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K23 mock treatment 0.406 0.14 2.01 0.257 0.0151 0.25 1.5976 0.7899 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 K24 mock treatment 0.255 -0.0107 -0.15 0.237 -0.00494 -0.08 -0.167 -0.9583 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L01 compound treatment 0.243 -0.0227 -0.32 0.24 -0.00194 -0.03 -0.2527 -0.774 3178709 Maybridge4_004467 CC(C)(C)c1cc(C(=O)Oc2ccc(Cl)cc2)n(Cc3ccccc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L02 compound treatment 0.278 0.0123 0.18 0.202 -0.0399 -0.67 -0.3497 -0.5047 3065631 Maybridge4_004468 CCOC(=O)c1cc(on1)C(=O)/C=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L03 compound treatment 0.532 0.266 3.81 0.191 -0.0509 -0.85 2.0887 0.5351 3178710 Maybridge4_004469 Cc1cc(no1)c2nnc(o2)c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L04 compound treatment 0.426 0.16 2.29 0.209 -0.0329 -0.55 1.2303 0.5217 3178711 Maybridge4_004470 CCOC(=O)c1nc(C)sc1c2ccnn2S(=O)(=O)c3ccccc3C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L05 compound treatment 0.498 0.232 3.32 0.277 0.0351 0.59 2.7655 0.8196 1698871 Maybridge4_004471 O=C(Nc1ccno1)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L06 compound treatment 0.396 0.13 1.86 0.411 0.169 2.84 3.3242 0.9792 3065632 Maybridge4_004472 COC(Cn1c(S)nnc1c2ccccc2)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L07 compound treatment 0.576 0.31 4.44 0.43 0.188 3.16 5.3702 0.9861 3178712 Maybridge4_004473 FC(F)(F)Oc1ccc(cc1)c2nnc(o2)c3cccnc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L08 compound treatment 0.518 0.252 3.61 0.401 0.159 2.67 4.4394 0.989 3178713 Maybridge4_004474 COC(Cn1c(SCC(=O)c2cccc(c2)C(F)(F)F)nnc1c3ccc(Cl)cc3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L09 compound treatment 0.505 0.239 3.42 0.392 0.15 2.52 4.2011 0.9886 3065633 Maybridge4_004475 CCOC(=O)c1c(Sc2ccccc2)cnn1C(=O)Nc3cccc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L10 compound treatment 0.558 0.292 4.18 0.453 0.211 3.54 5.4612 0.9966 3178714 Maybridge4_004476 COC(Cn1c(SCC(=O)Nc2cc(Cl)cc(Cl)c2)nnc1c3ccccc3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L11 compound treatment 0.546 0.28 4.01 0.453 0.211 3.54 5.3398 0.9981 3065634 Maybridge4_004477 Cc1ccc(CSc2ncccc2C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L12 compound treatment 0.552 0.286 4.09 0.452 0.21 3.53 5.3886 0.9972 3065635 Maybridge4_004478 CSc1nccc(n1)c2c(C)onc2c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L13 compound treatment 0.542 0.276 3.95 0.487 0.245 4.11 5.7028 0.9998 1231547 Maybridge4_004479 Cc1nccc(n1)c2nn(ccc2=O)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L14 compound treatment 0.351 0.0853 1.22 0.469 0.227 3.81 3.5574 0.889 3178715 Maybridge4_004480 Cc1cc(no1)c2nc(C)c(s2)c3nnc(SCC(=O)Nc4ccccc4)n3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L15 compound treatment 0.522 0.256 3.67 0.416 0.174 2.92 4.6579 0.9937 1650913 Maybridge4_004481 CN(C)C(=O)Oc1nc(C)nc(C)c1Oc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L16 compound treatment 0.559 0.293 4.2 0.445 0.203 3.41 5.3763 0.9947 3178716 Maybridge4_004482 Cc1c(sc2nc(nn12)c3ccc(Cl)cc3)C(=O)Oc4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L17 compound treatment 0.494 0.228 3.27 0.441 0.199 3.34 4.6714 0.9999 3065636 Maybridge4_004483 Cc1cc(no1)c2noc(n2)c3snnc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L18 compound treatment 0.572 0.306 4.38 0.468 0.226 3.79 5.7808 0.9974 1687470 Maybridge4_004484 O=c1[nH]c(Nc2ccccc2)c(C#N)c(=O)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L19 compound treatment 0.501 0.235 3.37 0.443 0.201 3.37 4.766 1.0 3178791 Maybridge4_004485 COC(OC)c1ccc(C#N)c(SCc2ccc(C)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L20 compound treatment 0.576 0.31 4.44 0.444 0.202 3.39 5.5364 0.9912 1451924 Maybridge4_004486 CSc1nc(COc2ccc(cc2)C(C)(C)C)nc(N)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L21 compound treatment 0.477 0.211 3.02 0.324 0.0821 1.38 3.1109 0.9367 3065637 Maybridge4_004487 FC(F)(F)c1cnc(S)c(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L22 compound treatment 0.553 0.287 4.11 0.303 0.0611 1.02 3.6304 0.8572 3178792 Maybridge4_004488 CCOC(=O)CSc1nc2sccn2c1/C=N/c3cc(Cl)cc(Cl)c3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L23 mock treatment 0.379 0.113 1.62 0.282 0.0401 0.67 1.6213 0.9241 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 L24 mock treatment 0.268 0.00229 0.03 0.285 0.0431 0.72 0.5342 0.7383 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M01 compound treatment 0.206 -0.0597 -0.85 0.236 -0.00594 -0.1 -0.6744 -0.7843 3065638 Maybridge4_004489 Cc1oc(cc1C(=O)C(=C2SCCS2)C#N)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M02 compound treatment 0.261 -0.00471 -0.07 0.255 0.0131 0.22 0.1073 0.468 3065639 Maybridge4_004490 Nc1nnc(SCc2nc(no2)c3ccccc3)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M03 compound treatment 0.507 0.241 3.45 0.225 -0.0169 -0.28 2.2394 0.6467 1454547 Maybridge4_004491 C1COc2ccc(cc2OC1)c3csc(n3)c4ccc(cc4)c5csnn5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M04 compound treatment 0.488 0.222 3.18 0.231 -0.0109 -0.18 2.1184 0.6652 3178793 Maybridge4_004492 CCN(CC)C(=O)Oc1nnc(SC(C)C)n1c2ccc(Cl)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M05 compound treatment 0.281 0.0153 0.22 0.196 -0.0459 -0.77 -0.3906 -0.4874 1188621 Maybridge4_004493 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)c2csc(n2)c3ccno3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M06 compound treatment 0.472 0.206 2.95 0.315 0.0731 1.23 2.9535 0.9243 3178794 Maybridge4_004494 Clc1ccccc1C(=O)Oc2ccc(cc2)C3=NCCS3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M07 compound treatment 0.454 0.188 2.69 0.38 0.138 2.32 3.5429 0.9972 3065640 Maybridge4_004495 Cc1ccc(cc1)c2noc(n2)c3cc(nn3Cc4ccccc4)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M08 compound treatment 0.428 0.162 2.32 0.409 0.167 2.8 3.6241 0.9956 3178795 Maybridge4_004496 COCc1cc(OC(=O)N(C)C)nc(COc2ccc(Cl)cc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M09 compound treatment 0.552 0.286 4.09 0.484 0.242 4.06 5.7684 1.0 1583006 Maybridge4_004497 Cc1c(cc(c2ccccc2)n1CCCN3CCOCC3)C(=O)Nc4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M10 compound treatment 0.495 0.229 3.28 0.445 0.203 3.41 4.729 0.9998 3065641 Maybridge4_004498 FC(F)(F)c1ccccc1C(=O)NC(=O)NN2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M11 compound treatment 0.437 0.171 2.45 0.315 0.0731 1.23 2.5995 0.9488 1136828 Maybridge4_004499 CSc1c(C#N)c(nn1c2ccccc2)c3cc(oc3C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M12 compound treatment 0.426 0.16 2.29 0.315 0.0731 1.23 2.4883 0.957 3065642 Maybridge4_004500 NNC(=O)c1cccc(COc2ccc(cc2)C3SCCS3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M13 compound treatment 0.485 0.219 3.14 0.475 0.233 3.91 4.9839 0.994 1241045 Maybridge4_004501 COc1ccc2[nH]c(cc2c1)C(=O)N(C)c3ccc(F)cc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M14 compound treatment 0.388 0.122 1.75 0.411 0.169 2.84 3.2433 0.973 1234233 Maybridge4_004502 COc1ccc(OC(=O)c2csc(Cc3c(Cl)cccc3Cl)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M15 compound treatment 0.153 -0.113 -1.61 0.277 0.0351 0.59 -0.7239 -0.4218 3178796 Maybridge4_004503 CSc1sc(C2=NNC(O)(C2)C(F)(F)F)c3c1C(=O)CCC3(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M16 compound treatment 0.456 0.19 2.72 0.435 0.193 3.24 4.2159 0.9962 3065643 Maybridge4_004504 Cc1nc(CS(=O)(=O)c2ccccn2)sc1C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M17 compound treatment 0.444 0.178 2.55 0.438 0.196 3.29 4.1301 0.9921 1507802 Maybridge4_004505 CN(C(=O)N1CCCCC1)c2c(C)onc2c3c(Cl)cccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M18 compound treatment 0.48 0.214 3.07 0.419 0.177 2.97 4.2687 0.9999 3178797 Maybridge4_004506 CN(C)/C=C/C(=O)c1sc(COc2ccccc2Cl)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M19 compound treatment 0.384 0.118 1.69 0.379 0.137 2.3 2.823 0.9886 3065644 Maybridge4_004507 Oc1cc(nc(Cc2c(Cl)cccc2Cl)n1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M20 compound treatment 0.402 0.136 1.95 0.388 0.146 2.45 3.1119 0.9936 3178798 Maybridge4_004508 CC(C)n1c(SCC(=O)C(C)(C)C)nc2cc(ccc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M21 compound treatment 0.465 0.199 2.85 0.321 0.0791 1.33 2.9539 0.9395 3065645 Maybridge4_004509 Oc1nnc(S)n1c2ccccc2C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M22 compound treatment 0.547 0.281 4.02 0.219 -0.0229 -0.38 2.5728 0.6365 3178799 Maybridge4_004510 Cc1cc(C)c(C#N)c(SCc2nc(COc3cccc(c3)C(F)(F)F)no2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M23 mock treatment 0.246 -0.0197 -0.28 0.291 0.0491 0.82 0.3829 0.4399 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 M24 mock treatment 0.268 0.00229 0.03 0.302 0.0601 1.01 0.7359 0.7297 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N01 compound treatment 0.28 0.0143 0.2 0.238 -0.00394 -0.07 0.0978 0.4552 3065646 Maybridge4_004511 CC(C)(C)c1cc(C(=O)Oc2cccc(c2)C(F)(F)F)n(Cc3ccccc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N02 compound treatment 0.264 -0.00171 -0.02 0.277 0.0351 0.59 0.3988 0.6771 1256051 Maybridge4_004512 CCOC(=O)c1nc(sc1c2ccnn2C(=O)NC(C)C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N03 compound treatment 0.323 0.0573 0.82 0.22 -0.0219 -0.37 0.319 0.3552 3065647 Maybridge4_004513 Cc1nn(c(C(=O)Sc2cccc(c2)C(F)(F)F)c1Br)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N04 compound treatment 0.501 0.235 3.37 0.263 0.0211 0.35 2.6297 0.7771 3178800 Maybridge4_004514 CCOC(=O)c1nc(C)sc1c2ccnn2S(=O)(=O)c3ccc(Cl)cc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N05 compound treatment 0.482 0.216 3.09 0.265 0.0231 0.39 2.4613 0.7894 1543758 Maybridge4_004515 O=C(NN1CCOCC1)Nc2ccno2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N06 compound treatment 0.486 0.22 3.15 0.275 0.0331 0.55 2.6204 0.819 3178801 Maybridge4_004516 COC(Cn1c(SCc2ccc(Cl)cc2)nnc1c3ccccc3)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N07 compound treatment 0.426 0.16 2.29 0.218 -0.0239 -0.4 1.3371 0.5744 3065648 Maybridge4_004517 Cc1ccc(SC(=O)c2ccc(OC(F)(F)F)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N08 compound treatment 0.543 0.277 3.97 0.274 0.0321 0.54 3.1851 0.7958 3178802 Maybridge4_004518 CN(C)/C=C/C(=O)c1c(C)onc1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N09 compound treatment 0.498 0.232 3.32 0.258 0.0161 0.27 2.54 0.762 3065649 Maybridge4_004519 COC(=O)c1noc(C)c1C(=O)/C=C/N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N10 compound treatment 0.477 0.211 3.02 0.255 0.0131 0.22 2.292 0.7564 3178803 Maybridge4_004520 COC(OC)c1c(cnn1c2ccccc2)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N11 compound treatment 0.599 0.333 4.77 0.232 -0.00994 -0.17 3.253 0.6819 3178804 Maybridge4_004521 CCOC(=O)c1cc(CSc2nnc(O)n2c3ccccc3)nn1C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N12 compound treatment 0.497 0.231 3.31 0.258 0.0161 0.27 2.5299 0.7622 3065650 Maybridge4_004522 CCOC(Cc1nnc(S)n1C)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N13 compound treatment 0.531 0.265 3.79 0.302 0.0601 1.01 3.396 0.865 1195492 Maybridge4_004523 CC(C)(C)c1nccc(n1)c2nn(ccc2=O)c3ccc(F)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N14 compound treatment 0.493 0.227 3.25 0.303 0.0611 1.02 3.0235 0.887 1316271 Maybridge4_004524 Clc1ccc(cc1)c2c(cnn2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N15 compound treatment 0.505 0.239 3.42 0.288 0.0461 0.77 2.9669 0.8455 3065651 Maybridge4_004525 CN(C)/C=C(/Sc1ccc(C)cc1)\C(=O)c2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N16 compound treatment 0.428 0.162 2.32 0.236 -0.00594 -0.1 1.5709 0.6761 3178805 Maybridge4_004526 Cc1c(NC(=O)Nc2ccccc2)sc3nc(nn13)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N17 compound treatment 0.518 0.252 3.61 0.284 0.0421 0.71 3.0509 0.8297 3065652 Maybridge4_004527 COCc1nc(S)c(C#N)cc1C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N18 compound treatment 0.5 0.234 3.35 0.233 -0.00894 -0.15 2.2635 0.6748 3065697 Maybridge4_004528 NC(=S)c1cnccc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N19 compound treatment 0.413 0.147 2.11 0.258 0.0161 0.27 1.6803 0.7911 3065698 Maybridge4_004529 COC(OC)c1ccc(C#N)c(SCC(=O)c2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N20 compound treatment 0.508 0.242 3.47 0.251 0.00906 0.15 2.5581 0.7374 3065699 Maybridge4_004530 COc1ccc(cc1)c2nc(COc3ccccc3Cl)nc(SC)c2C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N21 compound treatment 0.49 0.224 3.21 0.321 0.0791 1.33 3.2068 0.9237 1685558 Maybridge4_004531 CCOC(=O)c1cc(on1)c2csc(Nc3ccccc3Cl)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N22 compound treatment 0.377 0.111 1.59 0.287 0.0451 0.76 1.6604 0.9421 3065700 Maybridge4_004532 CSc1nnc(c2ccc(Cl)cc2Cl)n1Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N23 mock treatment 0.301 0.0353 0.5 0.301 0.0591 0.99 1.0578 0.951 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 N24 mock treatment 0.309 0.0433 0.62 0.297 0.0551 0.92 1.0913 0.981 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O01 compound treatment 0.193 -0.0727 -1.04 0.157 -0.0849 -1.43 -1.7435 -0.988 3065702 Maybridge4_004533 FC(F)(F)Oc1ccccc1NC(=S)NCc2ccc3OCCc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O02 compound treatment 0.286 0.0203 0.29 0.266 0.0241 0.4 0.4908 0.9868 3065703 Maybridge4_004534 CC(C)Sc1nnc(O)n1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O03 compound treatment 0.284 0.0183 0.26 0.224 -0.0179 -0.3 -0.0279 -0.0701 3065704 Maybridge4_004535 FC(F)(F)c1ccc(cc1)c2csc(n2)c3ccc(cc3)c4csnn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O04 compound treatment 0.268 0.00229 0.03 0.255 0.0131 0.22 0.1781 0.8037 1506889 Maybridge4_004536 Clc1ccc(CSCc2cc(=O)[nH]c(=O)[nH]2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O05 compound treatment 0.316 0.0503 0.72 0.288 0.0461 0.77 1.0553 0.9993 3178806 Maybridge4_004537 FC(F)(F)Oc1ccc(cc1)c2nc(CS(=O)(=O)Cc3ccco3)no2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O06 compound treatment 0.265 -7.14E-4 -0.01 0.285 0.0431 0.72 0.5038 0.697 3065705 Maybridge4_004538 FC(F)(F)c1ccc(cc1)c2nnc(SCC=C)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O07 compound treatment 0.243 -0.0227 -0.32 0.228 -0.0139 -0.23 -0.3951 -0.987 3178807 Maybridge4_004539 Fc1ccc(c2nc(no2)c3ccc(cc3)C(F)(F)F)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O08 compound treatment 0.228 -0.0377 -0.54 0.264 0.0221 0.37 -0.1196 -0.1828 3065706 Maybridge4_004540 FC(F)(F)c1ccc(cc1)C(=O)Sc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O09 compound treatment 0.231 -0.0347 -0.5 0.245 0.00306 0.05 -0.3148 -0.6305 1707697 Maybridge4_004541 Fc1ccc(cc1)n2nc(cc2NC(=O)C3CCC3)c4ccc(Cl)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O10 compound treatment 0.245 -0.0207 -0.3 0.225 -0.0169 -0.28 -0.4105 -0.9998 3065707 Maybridge4_004542 N/C(=N\O)/CS(=O)(=O)Cc1cccc(c1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O11 compound treatment 0.292 0.0263 0.38 0.243 0.00106 0.02 0.2785 0.7398 3178808 Maybridge4_004543 COC(=O)C1SCCN1C(=O)c2cc(oc2C)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O12 compound treatment 0.263 -0.00271 -0.04 0.262 0.0201 0.34 0.2107 0.6215 3065708 Maybridge4_004544 FC(F)(F)c1ccc(COc2ccc(C#N)cc2Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O13 compound treatment 0.18 -0.0857 -1.23 0.195 -0.0469 -0.79 -1.424 -0.9771 3178809 Maybridge4_004545 Cc1oc(cc1C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O14 compound treatment 0.22 -0.0457 -0.65 0.245 0.00306 0.05 -0.426 -0.6495 1687767 Maybridge4_004546 Clc1cccc(Cl)c1Cc2nc(cs2)C(=O)NCc3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O15 compound treatment 0.232 -0.0337 -0.48 0.216 -0.0259 -0.44 -0.6488 -0.9987 1449045 Maybridge4_004547 COC(=O)c1c(C)oc(C)c1S(=O)(=O)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O16 compound treatment 0.249 -0.0167 -0.24 0.234 -0.00794 -0.13 -0.2633 -0.9619 1404470 Maybridge4_004548 CCn1nc(C)cc1C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O17 compound treatment 0.053 -0.213 -3.04 0.05 -0.192 -3.22 -4.4294 -0.9996 3178810 Maybridge4_004549 CN(C)N/C(=N\O)/c1c(F)cccc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O18 compound treatment 0.215 -0.0507 -0.73 0.221 -0.0209 -0.35 -0.7614 -0.9446 3065709 Maybridge4_004550 N/C(=N\O)/COc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O19 compound treatment 0.218 -0.0477 -0.68 0.24 -0.00194 -0.03 -0.5056 -0.74 3178811 Maybridge4_004551 Oc1cc(nc(Cc2c(Cl)cccc2Cl)n1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O20 compound treatment 0.272 0.00629 0.09 0.249 0.00706 0.12 0.1474 0.9907 3065711 Maybridge4_004552 CCn1nc(C)c(Br)c1C(=O)Oc2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O21 compound treatment 0.315 0.0493 0.7 0.291 0.0491 0.82 1.0808 0.997 3178882 Maybridge4_004553 Cc1ccc(CSc2nnc([nH]2)c3ccc(cc3)C(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O22 compound treatment 0.244 -0.0217 -0.31 0.279 0.0371 0.62 0.2202 0.3168 3178883 Maybridge4_004554 Cc1cc(OCc2noc(CSc3ccc(cn3)C(F)(F)F)n2)cc(C)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O23 mock treatment 0.29 0.0243 0.35 0.227 -0.0149 -0.25 0.0684 0.1596 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 O24 mock treatment 0.26 -0.00571 -0.08 0.24 -0.00194 -0.03 -0.0808 -0.9184 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P01 compound treatment 0.169 -0.0967 -1.38 0.186 -0.0559 -0.94 -1.6421 -0.9822 1165145 Maybridge4_004555 CC(C)(C)c1cc(C(=O)Nc2ccc(Cl)cc2)n(Cc3ccccc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P02 compound treatment 0.237 -0.0287 -0.41 0.208 -0.0339 -0.57 -0.6932 -0.9871 3178884 Maybridge4_004556 CCOC(=O)c1cc(on1)c2ccnn2C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P03 compound treatment 0.331 0.0653 0.93 0.236 -0.00594 -0.1 0.5898 0.6281 3065712 Maybridge4_004557 Cc1cc(no1)c2onc(C)c2C(=O)Sc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P04 compound treatment 0.271 0.00529 0.08 0.258 0.0161 0.27 0.2441 0.8718 3178885 Maybridge4_004558 Cc1nc(nc(Sc2cccc(c2)C(F)(F)F)c1C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P05 compound treatment 0.3 0.0343 0.49 0.264 0.0221 0.37 0.6086 0.9904 3065713 Maybridge4_004559 CCOC(=O)c1noc(C)c1c2csc(COc3cc(Cl)cc(Cl)c3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P06 compound treatment 0.305 0.0393 0.56 0.249 0.00706 0.12 0.4812 0.8378 3178886 Maybridge4_004560 FC(F)(F)c1ccc(cc1)c2nc(cs2)c3cc(no3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P07 compound treatment 0.293 0.0273 0.39 0.234 -0.00794 -0.13 0.1818 0.4408 1465099 Maybridge4_004561 Cc1cc(no1)c2onc(C)c2C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P08 compound treatment 0.206 -0.0597 -0.85 0.278 0.0361 0.61 -0.176 -0.1681 1505757 Maybridge4_004562 Cc1nc2ccccn2c1c3ccnn3S(=O)(=O)c4ccc(C)cc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P09 compound treatment 0.233 -0.0327 -0.47 0.22 -0.0219 -0.37 -0.5912 -0.993 3065714 Maybridge4_004563 COC(=O)c1noc(C)c1c2ccnn2C(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P10 compound treatment 0.227 -0.0387 -0.55 0.241 -9.38E-4 -0.02 -0.4027 -0.7269 3178887 Maybridge4_004564 COC(=O)c1cnn(c1/C=N/c2ccc(C)cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P11 compound treatment 0.285 0.0193 0.28 0.265 0.0231 0.39 0.4688 0.9862 3178888 Maybridge4_004565 CC(C)(C)c1ccc(cc1Cn2nnc(n2)c3cccc(c3)C(F)(F)F)c4ncon4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P12 compound treatment 0.258 -0.00771 -0.11 0.236 -0.00594 -0.1 -0.1485 -0.9987 1198897 Maybridge4_004566 CC(=O)N(C(=O)C)c1nccc(n1)c2c(C)onc2c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P13 compound treatment 0.307 0.0413 0.59 0.259 0.0171 0.29 0.6201 0.9448 1188766 Maybridge4_004567 Clc1ccc(cc1)n2ccc(=O)c(n2)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P14 compound treatment 0.22 -0.0457 -0.65 0.245 0.00306 0.05 -0.426 -0.6495 1729683 Maybridge4_004568 CC(C)NC(=O)n1ncc(c1c2ccc(Cl)cc2)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P15 compound treatment 0.269 0.00329 0.05 0.257 0.0151 0.25 0.212 0.8244 1416020 Maybridge4_004569 Cc1[nH]c(=S)[nH]c(=O)c1Oc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P16 compound treatment 0.318 0.0523 0.75 0.217 -0.0249 -0.42 0.2329 0.2717 3065738 Maybridge4_004570 Cc1c(sc2nc(nn12)C(F)(F)F)C(=O)Sc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P17 compound treatment 0.211 -0.0547 -0.78 0.157 -0.0849 -1.43 -1.5614 -0.9601 1418463 Maybridge4_004571 CCOC(=O)c1cc(C#N)c(S)nc1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P18 compound treatment 0.269 0.00329 0.05 0.252 0.0101 0.17 0.1527 0.8708 3065739 Maybridge4_004572 Cn1c(S)nnc1c2ncc(cc2Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P19 compound treatment 0.256 -0.00971 -0.14 0.28 0.0381 0.64 0.3535 0.5407 3065740 Maybridge4_004573 Cc1onc(C(=O)NN)c1c2csc(COc3ccc(Cl)cc3)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P20 compound treatment 0.267 0.00129 0.02 0.278 0.0361 0.61 0.441 0.7283 1093995 Maybridge4_004574 NC(=S)COc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P21 compound treatment 0.314 0.0483 0.69 0.335 0.0931 1.56 1.5928 0.9327 3178889 Maybridge4_004575 Cc1cc(no1)c2nc(cs2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P22 compound treatment 0.326 0.0603 0.86 0.3 0.0581 0.97 1.2988 0.9981 3065741 Maybridge4_004576 CC(C)S(=O)(=O)/C(=C/N1CCC(CC1)C(F)(F)F)/C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P23 mock treatment 0.276 0.0103 0.15 0.252 0.0101 0.17 0.2235 0.9976 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2061 P24 mock treatment 0.248 -0.0177 -0.25 0.219 -0.0229 -0.38 -0.4514 -0.9794 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A01 compound treatment 0.253 -0.0493 -0.71 0.237 -0.0284 -0.48 -0.8358 -0.9817 3178890 Maybridge4_004577 CC(C)(C)c1ccc(SC(=O)c2ccc(OCC(F)(F)F)nc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A02 compound treatment 0.307 0.00466 0.07 0.288 0.0226 0.38 0.3156 0.8188 1333720 Maybridge4_004578 COc1ccc(OCc2ncc(s2)c3ccc4OCCCOc4c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A03 compound treatment 0.2 -0.102 -1.46 0.18 -0.0854 -1.43 -2.0484 -0.9999 1593366 Maybridge4_004579 Cc1nn(c(N)c1c2nc(cs2)c3ccccc3)c4cc(Cl)ccc4Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A04 compound treatment 0.231 -0.0713 -1.02 0.266 6.19E-4 0.01 -0.7142 -0.6999 3178891 Maybridge4_004580 Cc1ccc(cc1F)c2nc(cs2)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A05 compound treatment 0.249 -0.0533 -0.76 0.206 -0.0594 -1.0 -1.2442 -0.9913 3065742 Maybridge4_004581 FC(F)(F)Oc1ccc(cc1)C(=O)Nc2ccc(nc2)N3CCC(CC3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A06 compound treatment 0.253 -0.0493 -0.71 0.203 -0.0624 -1.05 -1.2394 -0.9816 3178892 Maybridge4_004582 Cc1c(C#N)c(SCc2cccc(c2)C(F)(F)F)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A07 compound treatment 0.21 -0.0923 -1.32 0.205 -0.0604 -1.01 -1.6505 -0.9914 3178893 Maybridge4_004583 CCOC(=O)c1cc(C#N)c(Sc2ccc(C)cc2)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A08 compound treatment 0.238 -0.0643 -0.92 0.189 -0.0764 -1.28 -1.5572 -0.9868 3065743 Maybridge4_004584 Cn1nc(c2cccc(c2)C3OCCO3)c(=O)n(C)c1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A09 compound treatment 0.203 -0.0993 -1.42 0.245 -0.0204 -0.34 -1.2466 -0.853 3178894 Maybridge4_004585 Cc1nc(cs1)C(=N)NC(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A10 compound treatment 0.215 -0.0873 -1.25 0.233 -0.0324 -0.54 -1.2677 -0.9305 3065744 Maybridge4_004586 CC1=N/C(=C\c2sccc2C)/C(=O)O1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A11 compound treatment 0.249 -0.0533 -0.76 0.193 -0.0724 -1.21 -1.3985 -0.9749 1220314 Maybridge4_004587 Cc1cc(C)n(Cc2ccccc2)c(=O)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A12 compound treatment 0.199 -0.103 -1.48 0.197 -0.0684 -1.15 -1.8567 -0.9922 3178895 Maybridge4_004588 Cc1ccccc1c2nnc(o2)c3cc(nn3Cc4ccc(F)cc4)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A13 compound treatment 0.226 -0.0763 -1.09 0.236 -0.0294 -0.49 -1.1208 -0.9355 3178896 Maybridge4_004589 FC(F)(F)COc1ccc(cn1)c2nnc(SCc3ccccc3C(F)(F)F)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A14 compound treatment 0.193 -0.109 -1.56 0.155 -0.11 -1.85 -2.4159 -0.9964 3065746 Maybridge4_004590 CN(C)/C=C/C(=O)C1(CC2CC3CC(C2)C1)C3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A15 compound treatment 0.264 -0.0383 -0.55 0.235 -0.0304 -0.51 -0.7483 -0.9993 3178897 Maybridge4_004591 CCOC(=O)c1cc(C#N)c(nc1C(F)(F)F)N2CCN(CC2)C(=O)c3snnc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A16 compound treatment 0.227 -0.0753 -1.08 0.262 -0.00338 -0.06 -0.8021 -0.7433 3065747 Maybridge4_004592 CC1CCCCN1C(=S)Nc2cccc(C)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A17 compound treatment 0.255 -0.0473 -0.68 0.226 -0.0394 -0.66 -0.9462 -0.9999 3178898 Maybridge4_004593 FC(F)(F)c1ccc(nc1)c2nnc(c3ccccn3)c(n2)c4ccccn4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A18 compound treatment 0.218 -0.0843 -1.21 0.212 -0.0534 -0.9 -1.4865 -0.9893 3065748 Maybridge4_004594 CC(C)n1c(=S)[nH]c2cc(ccc12)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A19 compound treatment 0.255 -0.0473 -0.68 0.185 -0.0804 -1.35 -1.4328 -0.9492 3178899 Maybridge4_004595 COc1ccc(OCC(=N)NC(=S)Nc2ccc(Cl)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A20 compound treatment 0.196 -0.106 -1.52 0.236 -0.0294 -0.49 -1.4242 -0.8907 3065749 Maybridge4_004596 Clc1ccc(NC(=C(C#N)C#N)NC(=O)c2ccccc2Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A21 compound treatment 0.249 -0.0533 -0.76 0.259 -0.00638 -0.11 -0.6152 -0.7985 3178900 Maybridge4_004597 FC(F)(F)c1cc(nc(Sc2ccccc2NC(=O)c3cccs3)c1C#N)c4cccs4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A22 mock treatment 0.428 0.126 1.8 0.447 0.182 3.05 3.4264 0.9683 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A23 mock treatment 0.209 -0.0933 -1.34 0.269 0.00362 0.06 -0.9011 -0.6742 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 A24 mock treatment 0.226 -0.0763 -1.09 0.223 -0.0424 -0.71 -1.2751 -0.9784 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B01 mock treatment 0.426 0.124 1.77 0.433 0.168 2.81 3.2401 0.975 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B02 mock treatment 0.2 -0.102 -1.46 0.204 -0.0614 -1.03 -1.7635 -0.9852 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B03 mock treatment 0.211 -0.0913 -1.31 0.225 -0.0404 -0.68 -1.4031 -0.9533 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B04 mock treatment 0.252 -0.0503 -0.72 0.234 -0.0314 -0.53 -0.8816 -0.9882 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B05 mock treatment 0.226 -0.0763 -1.09 0.261 -0.00438 -0.07 -0.8241 -0.753 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B06 mock treatment 0.233 -0.0693 -0.99 0.231 -0.0344 -0.58 -1.1093 -0.9668 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B07 mock treatment 0.256 -0.0463 -0.66 0.254 -0.0114 -0.19 -0.6037 -0.8753 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B08 mock treatment 0.414 0.112 1.6 0.257 -0.00838 -0.14 1.0299 0.6423 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B09 mock treatment 0.258 -0.0443 -0.63 0.229 -0.0364 -0.61 -0.8802 -0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B10 mock treatment 0.247 -0.0553 -0.79 0.245 -0.0204 -0.34 -0.8016 -0.9296 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B11 mock treatment 0.413 0.111 1.58 0.427 0.162 2.71 3.0374 0.9671 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B12 mock treatment 0.236 -0.0663 -0.95 0.205 -0.0604 -1.01 -1.3876 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B13 mock treatment 0.424 0.122 1.74 0.217 -0.0484 -0.81 0.6563 0.3418 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B14 mock treatment 0.319 0.0167 0.24 0.228 -0.0374 -0.63 -0.2751 -0.4099 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B15 mock treatment 0.203 -0.0993 -1.42 0.223 -0.0424 -0.71 -1.5077 -0.9488 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B16 mock treatment 0.426 0.124 1.77 0.215 -0.0504 -0.85 0.6528 0.333 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B17 mock treatment 0.442 0.14 2.0 0.24 -0.0254 -0.43 1.1113 0.5441 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B18 mock treatment 0.422 0.12 1.71 0.211 -0.0544 -0.91 0.5649 0.2912 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B19 mock treatment 0.444 0.142 2.03 0.253 -0.0124 -0.21 1.2859 0.6313 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B20 mock treatment 0.435 0.133 1.9 0.429 0.164 2.75 3.2836 0.9837 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B21 mock treatment 0.454 0.152 2.17 0.243 -0.0224 -0.38 1.2683 0.5761 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B22 mock treatment 0.441 0.139 1.98 0.451 0.186 3.12 3.6054 0.9762 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B23 mock treatment 0.271 -0.0313 -0.45 0.232 -0.0334 -0.56 -0.7131 -0.9939 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 B24 mock treatment 0.252 -0.0503 -0.72 0.216 -0.0494 -0.83 -1.0952 -0.9975 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C01 compound treatment 0.231 -0.0713 -1.02 0.218 -0.0474 -0.8 -1.2839 -0.9924 3065750 Maybridge4_004598 FC(F)(F)c1cccc(NC(=O)CCn2cccc(c2=O)C(F)(F)F)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C02 compound treatment 0.235 -0.0673 -0.96 0.168 -0.0974 -1.63 -1.8368 -0.9682 3178901 Maybridge4_004599 Oc1ccc2c(CSc3ccc(Cl)cc3)cc(=O)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C03 compound treatment 0.311 0.00866 0.12 0.215 -0.0504 -0.85 -0.5103 -0.5971 3178902 Maybridge4_004600 CN(CCOC(=O)c1snnc1C)c2ccc(C#N)cn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C04 compound treatment 0.189 -0.113 -1.62 0.205 -0.0604 -1.01 -1.8629 -0.9744 1339676 Maybridge4_004601 Cn1nc(cc1C(=O)Nc2cccnc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C05 compound treatment 0.268 -0.0343 -0.49 0.266 6.19E-4 0.01 -0.34 -0.692 3065771 Maybridge4_004602 CCCNC(=O)Nc1ccc(nc1)N2CCC(CC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C06 compound treatment 0.238 -0.0643 -0.92 0.226 -0.0394 -0.66 -1.1181 -0.9868 1741890 Maybridge4_004603 Cc1cc(C(=O)Nc2ccc(C)cc2)n(Cc3ccc(C)cc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C07 compound treatment 0.286 -0.0163 -0.23 0.201 -0.0644 -1.08 -0.9293 -0.8406 3065772 Maybridge4_004604 CCOC(=O)c1cc(C#N)c(Nc2ccccc2OC)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C08 compound treatment 0.26 -0.0423 -0.61 0.232 -0.0334 -0.56 -0.8244 -0.9992 3065773 Maybridge4_004605 N#Cc1ccc(nc1)N2CCCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C09 compound treatment 0.291 -0.0113 -0.16 0.243 -0.0224 -0.38 -0.3803 -0.9295 3065774 Maybridge4_004606 Cc1nc(cs1)C(=N)NC(=O)c2ccc(OC(F)(F)F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C10 compound treatment 0.248 -0.0543 -0.78 0.228 -0.0374 -0.63 -0.9932 -0.9944 3065775 Maybridge4_004607 N[C@@H](Cc1ccc(OC(F)(F)F)cc1)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C11 compound treatment 0.232 -0.0703 -1.01 0.211 -0.0544 -0.91 -1.3568 -0.9988 3065776 Maybridge4_004608 Cn1c(SCC(=O)Nc2cccc(Cl)c2)nnc1c3ccc(OCC(F)(F)F)nc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C12 compound treatment 0.188 -0.114 -1.64 0.213 -0.0524 -0.88 -1.7781 -0.9576 3065777 Maybridge4_004609 Cc1cc(nn1C(C)(C)C)C(=O)Nc2ccc(C)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C13 compound treatment 0.289 -0.0133 -0.19 0.265 -3.81E-4 -0.01 -0.1394 -0.7304 3178903 Maybridge4_004610 CSc1nnc(c2cc(OCC(F)(F)F)nc(OCC(F)(F)F)c2)n1Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C14 compound treatment 0.194 -0.108 -1.55 0.167 -0.0984 -1.65 -2.2634 -0.9995 3065778 Maybridge4_004611 Fc1ccc(SCC(=O)C2(CC3CC4CC(C3)C2)C4)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C15 compound treatment 0.196 -0.106 -1.52 0.201 -0.0644 -1.08 -1.8396 -0.986 3178904 Maybridge4_004612 FC(F)(F)c1ccc(nc1)c2nnc(SCC(=O)Nc3cccc(Cl)c3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C16 compound treatment 0.293 -0.00934 -0.13 0.274 0.00862 0.14 0.0078 0.0398 3065781 Maybridge4_004613 Cc1cccc(NC(=S)N2CCCCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C17 compound treatment 0.053 -0.249 -3.57 0.05 -0.215 -3.61 -5.078 -1.0 3178905 Maybridge4_004614 Fc1cccc(c1)C(=O)CSC2=NNC(S2)c3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C18 compound treatment 0.203 -0.0993 -1.42 0.244 -0.0214 -0.36 -1.2585 -0.8587 3065782 Maybridge4_004615 Cn1c(SCC=C)ncc1c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C19 compound treatment 0.269 -0.0333 -0.48 0.195 -0.0704 -1.18 -1.1725 -0.9204 3178906 Maybridge4_004616 Cc1ccc(NC(=S)NC(=N)COc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C20 compound treatment 0.165 -0.137 -1.96 0.138 -0.127 -2.14 -2.9008 -0.9991 3065783 Maybridge4_004617 Sc1nnc(SCC2CC2)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C21 compound treatment 0.193 -0.109 -1.56 0.193 -0.0724 -1.21 -1.9649 -0.9922 1187470 Maybridge4_004618 NC(=S)c1ccc(nc1)n2cncn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C22 mock treatment 0.223 -0.0793 -1.13 0.226 -0.0394 -0.66 -1.2698 -0.9669 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C23 mock treatment 0.257 -0.0453 -0.65 0.197 -0.0684 -1.15 -1.2701 -0.9635 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 C24 mock treatment 0.221 -0.0813 -1.16 0.202 -0.0634 -1.06 -1.5749 -0.999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D01 mock treatment 0.217 -0.0853 -1.22 0.23 -0.0354 -0.59 -1.283 -0.9452 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D02 mock treatment 0.208 -0.0943 -1.35 0.238 -0.0274 -0.46 -1.2791 -0.8973 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D03 mock treatment 0.215 -0.0873 -1.25 0.209 -0.0564 -0.95 -1.5525 -0.9906 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D04 mock treatment 0.213 -0.0893 -1.28 0.212 -0.0534 -0.9 -1.5371 -0.9849 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D05 mock treatment 0.259 -0.0433 -0.62 0.275 0.00962 0.16 -0.3242 -0.5061 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D06 mock treatment 0.251 -0.0513 -0.73 0.187 -0.0784 -1.32 -1.4495 -0.9621 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D07 mock treatment 0.293 -0.00934 -0.13 0.236 -0.0294 -0.49 -0.4431 -0.8674 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D08 mock treatment 0.263 -0.0393 -0.56 0.294 0.0286 0.48 -0.0582 -0.0787 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D09 mock treatment 0.424 0.122 1.74 0.289 0.0236 0.4 1.5108 0.8465 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D10 mock treatment 0.278 -0.0243 -0.35 0.269 0.00362 0.06 -0.2032 -0.575 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D11 mock treatment 0.415 0.113 1.61 0.245 -0.0204 -0.34 0.8976 0.5449 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D12 mock treatment 0.264 -0.0383 -0.55 0.233 -0.0324 -0.54 -0.7721 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D13 mock treatment 0.379 0.0767 1.1 0.29 0.0246 0.41 1.0676 0.911 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D14 mock treatment 0.378 0.0757 1.08 0.328 0.0626 1.05 1.5084 0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D15 mock treatment 0.278 -0.0243 -0.35 0.343 0.0776 1.3 0.675 0.5006 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D16 mock treatment 0.451 0.149 2.13 0.437 0.172 2.88 3.5404 0.9888 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D17 mock treatment 0.44 0.138 1.97 0.463 0.198 3.32 3.7377 0.969 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D18 mock treatment 0.317 0.0147 0.21 0.275 0.00962 0.16 0.2625 0.9917 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D19 mock treatment 0.289 -0.0133 -0.19 0.304 0.0386 0.65 0.3234 0.4787 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D20 mock treatment 0.366 0.0637 0.91 0.233 -0.0324 -0.54 0.2596 0.2448 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D21 mock treatment 0.351 0.0487 0.7 0.313 0.0476 0.8 1.0573 0.9976 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D22 mock treatment 0.321 0.0187 0.27 0.295 0.0296 0.5 0.5403 0.9575 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D23 mock treatment 0.249 -0.0533 -0.76 0.243 -0.0224 -0.38 -0.8051 -0.9467 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 D24 mock treatment 0.221 -0.0813 -1.16 0.237 -0.0284 -0.48 -1.1595 -0.9223 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E01 compound treatment 0.278 -0.0243 -0.35 0.294 0.0286 0.48 0.0935 0.1576 3178907 Maybridge4_004619 FC(F)(F)c1cccn(CCC(=O)Sc2ccccc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E02 compound treatment 0.23 -0.0723 -1.03 0.218 -0.0474 -0.8 -1.294 -0.9915 1539590 Maybridge4_004620 Oc1ccc2c(CSc3ccccn3)cc(=O)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E03 compound treatment 0.204 -0.0983 -1.41 0.201 -0.0644 -1.08 -1.7587 -0.9915 3178908 Maybridge4_004621 NC(=S)c1ccc(nc1)N2CCC(CC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E04 compound treatment 0.201 -0.101 -1.45 0.204 -0.0614 -1.03 -1.7534 -0.986 3178909 Maybridge4_004622 Cc1cccc(Cl)c1OC(=O)c2cc(nn2C)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E05 compound treatment 0.189 -0.113 -1.62 0.218 -0.0474 -0.8 -1.7087 -0.9463 3065784 Maybridge4_004623 OC(=O)CCn1cc(ccc1=O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E06 compound treatment 0.275 -0.0273 -0.39 0.227 -0.0384 -0.64 -0.732 -0.9714 1605604 Maybridge4_004624 Cc1cc(C(=O)Sc2ccccc2)n(Cc3ccc(C)cc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E07 compound treatment 0.282 -0.0203 -0.29 0.231 -0.0344 -0.58 -0.6137 -0.9497 3065785 Maybridge4_004625 FC(F)(F)c1cccn(Cc2ccccc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E08 compound treatment 0.265 -0.0373 -0.53 0.256 -0.00938 -0.16 -0.489 -0.8782 3178983 Maybridge4_004626 O=c1[nH]nc(SCc2ccccc2)n1c3ccc(OCc4ccccc4)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E09 compound treatment 0.25 -0.0523 -0.75 0.23 -0.0354 -0.59 -0.9493 -0.9934 3065786 Maybridge4_004627 Cn1c(S)nnc1Cn2cc(ccc2=O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E10 compound treatment 0.201 -0.101 -1.45 0.229 -0.0364 -0.61 -1.4567 -0.9262 3178984 Maybridge4_004628 CC(=O)N/C(=C/c1ccc(Cl)c(Cl)c1)/C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E11 compound treatment 0.272 -0.0303 -0.43 0.176 -0.0894 -1.5 -1.3676 -0.8757 3065787 Maybridge4_004629 Cn1c(SCc2ccc(cc2)C(F)(F)F)nnc1c3ccc(OCC(F)(F)F)nc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E12 compound treatment 0.245 -0.0573 -0.82 0.232 -0.0334 -0.56 -0.9761 -0.9827 3178985 Maybridge4_004630 Clc1ccc(cc1)c2nnc(SCC3CC3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E13 compound treatment 0.278 -0.0243 -0.35 0.229 -0.0364 -0.61 -0.6779 -0.9645 3178986 Maybridge4_004631 Cc1ccccc1NC(=O)c2cccc(Cn3cc(ccc3=O)C(F)(F)F)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E14 compound treatment 0.202 -0.1 -1.44 0.252 -0.0134 -0.22 -1.1737 -0.8079 1516971 Maybridge4_004632 Cc1ccc(cc1)C(=O)CSc2nnc(o2)c3cc(nn3Cc4cccc(C)c4)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E15 compound treatment 0.245 -0.0573 -0.82 0.258 -0.00738 -0.12 -0.6675 -0.8048 3178987 Maybridge4_004633 NNC(=N)c1ccc(cn1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E16 compound treatment 0.261 -0.0413 -0.59 0.26 -0.00538 -0.09 -0.482 -0.8058 3065788 Maybridge4_004634 CC(C)N(CCC#N)CN1C(=O)c2ccccc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E17 compound treatment 0.069 -0.233 -3.34 0.05 -0.215 -3.61 -4.9162 -0.9992 3065812 Maybridge4_004635 CC(C)c1ccc(NC(=O)CSC2=NNC(S2)c3ccccn3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E18 compound treatment 0.26 -0.0423 -0.61 0.261 -0.00438 -0.07 -0.4802 -0.7872 3065813 Maybridge4_004636 Clc1ccc(N/C(=N\C#N)/Oc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E19 compound treatment 0.197 -0.105 -1.51 0.194 -0.0714 -1.2 -1.9126 -0.9936 1232015 Maybridge4_004637 Sc1nc2CCCCc2c(c3cccs3)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E20 compound treatment 0.242 -0.0603 -0.86 0.194 -0.0714 -1.2 -1.4574 -0.987 3065814 Maybridge4_004638 CC(Sc1ccc(C)cc1)C(=O)c2ccc(C)c(Cl)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E21 compound treatment 0.085 -0.217 -3.11 0.16 -0.105 -1.77 -3.4489 -0.9643 3065815 Maybridge4_004639 CCOC(=O)c1nc(C)nc(Sc2nnc([nH]2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E22 mock treatment 0.284 -0.0183 -0.26 0.217 -0.0484 -0.81 -0.7597 -0.8902 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E23 mock treatment 0.221 -0.0813 -1.16 0.251 -0.0144 -0.24 -0.9933 -0.836 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 E24 mock treatment 0.209 -0.0933 -1.34 0.202 -0.0634 -1.06 -1.6963 -0.9937 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F01 mock treatment 0.44 0.138 1.97 0.428 0.163 2.73 3.3223 0.9872 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F02 mock treatment 0.216 -0.0863 -1.23 0.229 -0.0364 -0.61 -1.305 -0.9473 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F03 mock treatment 0.206 -0.0963 -1.38 0.225 -0.0404 -0.68 -1.4536 -0.9466 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F04 mock treatment 0.238 -0.0643 -0.92 0.214 -0.0514 -0.86 -1.2605 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F05 mock treatment 0.245 -0.0573 -0.82 0.192 -0.0734 -1.23 -1.4508 -0.9805 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F06 mock treatment 0.291 -0.0113 -0.16 0.25 -0.0154 -0.26 -0.2972 -0.9749 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F07 mock treatment 0.345 0.0427 0.61 0.316 0.0506 0.85 1.0322 0.9868 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F08 mock treatment 0.335 0.0327 0.47 0.257 -0.00838 -0.14 0.2309 0.4732 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F09 mock treatment 0.32 0.0177 0.25 0.291 0.0256 0.43 0.4827 0.9679 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F10 mock treatment 0.311 0.00866 0.12 0.254 -0.0114 -0.19 -0.0475 -0.2085 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F11 mock treatment 0.321 0.0187 0.27 0.267 0.00162 0.03 0.208 0.7751 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F12 mock treatment 0.366 0.0637 0.91 0.335 0.0696 1.17 1.4701 0.9924 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F13 mock treatment 0.363 0.0607 0.87 0.428 0.163 2.73 2.5435 0.8881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F14 mock treatment 0.336 0.0337 0.48 0.287 0.0216 0.36 0.597 0.9903 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F15 mock treatment 0.368 0.0657 0.94 0.317 0.0516 0.87 1.2767 0.9992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F16 mock treatment 0.388 0.0857 1.23 0.355 0.0896 1.5 1.93 0.9948 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F17 mock treatment 0.374 0.0717 1.03 0.366 0.101 1.69 1.919 0.9714 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F18 mock treatment 0.377 0.0747 1.07 0.342 0.0766 1.29 1.6645 0.9957 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F19 mock treatment 0.309 0.00666 0.1 0.311 0.0456 0.77 0.6088 0.789 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F20 mock treatment 0.428 0.126 1.8 0.442 0.177 2.96 3.3671 0.9713 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F21 mock treatment 0.356 0.0537 0.77 0.28 0.0146 0.25 0.7162 0.8888 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F22 mock treatment 0.358 0.0557 0.8 0.277 0.0116 0.2 0.7009 0.855 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F23 mock treatment 0.237 -0.0653 -0.93 0.263 -0.00238 -0.04 -0.6891 -0.7367 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 F24 mock treatment 0.221 -0.0813 -1.16 0.235 -0.0304 -0.51 -1.1832 -0.9315 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G01 compound treatment 0.206 -0.0963 -1.38 0.205 -0.0604 -1.01 -1.691 -0.9886 3065816 Maybridge4_004640 Cc1nc(N)nc(CSc2ccccc2)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G02 compound treatment 0.211 -0.0913 -1.31 0.188 -0.0774 -1.3 -1.8422 -1.0 3065817 Maybridge4_004641 Oc1ccc2c(CSc3nnc([nH]3)c4cccs4)cc(=O)oc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G03 compound treatment 0.264 -0.0383 -0.55 0.251 -0.0144 -0.24 -0.5584 -0.932 1387671 Maybridge4_004642 CN(CCOC(=O)Nc1cccc(Cl)c1)c2ccc(C#N)cn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G04 compound treatment 0.237 -0.0653 -0.93 0.314 0.0486 0.82 -0.0838 -0.0676 1420583 Maybridge4_004643 Clc1ccc(CSc2n[nH]c(=O)n2C3CC4CC3C=C4)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G05 compound treatment 0.215 -0.0873 -1.25 0.242 -0.0234 -0.39 -1.1608 -0.8865 3178988 Maybridge4_004644 COC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G06 compound treatment 0.287 -0.0153 -0.22 0.246 -0.0194 -0.33 -0.3852 -0.9816 3065818 Maybridge4_004645 Cc1cc(nn1Cc2ccc(C)cc2)C(=O)Sc3cccc(Cl)c3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G07 compound treatment 0.26 -0.0423 -0.61 0.278 0.0126 0.21 -0.2785 -0.434 3178989 Maybridge4_004646 FC(F)(F)c1cccn(CC(=O)c2ccc(Cl)cc2)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G08 compound treatment 0.323 0.0207 0.3 0.291 0.0256 0.43 0.513 0.9833 1219573 Maybridge4_004647 CC(C)(C)c1cc(NC(=O)CSc2n[nH]c(=O)n2c3ccc4OCCOc4c3)cc(c1)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G09 compound treatment 0.291 -0.0113 -0.16 0.219 -0.0464 -0.78 -0.6651 -0.8365 3065819 Maybridge4_004648 CCOC(=O)c1cnc(nc1Sc2nnc([nH]2)c3cccs3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G10 compound treatment 0.298 -0.00434 -0.06 0.272 0.00662 0.11 0.0347 0.2725 1396971 Maybridge4_004649 CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)c2nnc(S)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G11 compound treatment 0.091 -0.211 -3.02 0.096 -0.169 -2.84 -4.1478 -0.9995 3065820 Maybridge4_004650 CCOC(=O)c1cc(C#N)c(Sc2ccccc2NC(=O)c3ccccc3)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G12 compound treatment 0.266 -0.0363 -0.52 0.185 -0.0804 -1.35 -1.3215 -0.914 1227698 Maybridge4_004651 Cc1cccc(Cn2nc(cc2C(=O)Nc3cccnc3)C(C)(C)C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G13 compound treatment 0.265 -0.0373 -0.53 0.258 -0.00738 -0.12 -0.4652 -0.8486 3065822 Maybridge4_004652 FC(F)(F)c1ccc(=O)n(Cc2cccc(c2)C(=O)Sc3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G14 compound treatment 0.271 -0.0313 -0.45 0.223 -0.0424 -0.71 -0.8199 -0.9752 3178991 Maybridge4_004653 CCOC(=O)C1CCN(CC1)c2nc(c(cc2C#N)C(=O)OCC)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G15 compound treatment 0.305 0.00266 0.04 0.258 -0.00738 -0.12 -0.0607 -0.4682 1653461 Maybridge4_004654 CC(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G16 compound treatment 0.304 0.00166 0.02 0.217 -0.0484 -0.81 -0.5574 -0.6861 3178992 Maybridge4_004655 CC(C)N(CCC#N)C(=S)Nc1c(C)cccc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G17 compound treatment 0.251 -0.0513 -0.73 0.278 0.0126 0.21 -0.3695 -0.4834 3065823 Maybridge4_004656 COC(=N)NC(=S)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G18 compound treatment 0.287 -0.0153 -0.22 0.267 0.00162 0.03 -0.1359 -0.6148 1122990 Maybridge4_004657 CC(C)NC(=O)Nc1nc(Nc2ccc(Cl)cc2)n[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G19 compound treatment 0.228 -0.0743 -1.06 0.25 -0.0154 -0.26 -0.9344 -0.854 3178993 Maybridge4_004658 N1N=C(NC1c2cccnc2)c3cnccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G20 compound treatment 0.227 -0.0753 -1.08 0.236 -0.0294 -0.49 -1.1107 -0.9372 1235857 Maybridge4_004659 Cc1c(C#N)c(=N)n(nc1C(=O)Nc2ccccc2)c3ccc(cc3)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G21 compound treatment 0.267 -0.0353 -0.51 0.227 -0.0384 -0.64 -0.8129 -0.9928 3178994 Maybridge4_004660 CCOC(=O)c1sc2nc(c(cc2c1NC(=O)C)C(=O)OCC)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G22 mock treatment 0.338 0.0357 0.51 0.287 0.0216 0.36 0.6173 0.9861 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G23 mock treatment 0.193 -0.109 -1.56 0.232 -0.0334 -0.56 -1.502 -0.9042 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 G24 mock treatment 0.219 -0.0833 -1.19 0.23 -0.0354 -0.59 -1.2628 -0.9482 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H01 mock treatment 0.418 0.116 1.65 0.221 -0.0444 -0.74 0.6431 0.3545 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H02 mock treatment 0.22 -0.0823 -1.18 0.218 -0.0474 -0.8 -1.3951 -0.9817 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H03 mock treatment 0.269 -0.0333 -0.48 0.198 -0.0674 -1.13 -1.1369 -0.9263 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H04 mock treatment 0.228 -0.0743 -1.06 0.236 -0.0294 -0.49 -1.1006 -0.939 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H05 mock treatment 0.301 -0.00134 -0.02 0.213 -0.0524 -0.88 -0.6352 -0.7223 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H06 mock treatment 0.301 -0.00134 -0.02 0.238 -0.0274 -0.46 -0.3385 -0.7359 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H07 mock treatment 0.318 0.0157 0.22 0.312 0.0466 0.78 0.7117 0.8744 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H08 mock treatment 0.326 0.0237 0.34 0.307 0.0416 0.7 0.7333 0.9447 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H09 mock treatment 0.367 0.0647 0.92 0.266 6.19E-4 0.01 0.6613 0.715 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H10 mock treatment 0.312 0.00966 0.14 0.307 0.0416 0.7 0.5917 0.8309 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H11 mock treatment 0.354 0.0517 0.74 0.29 0.0246 0.41 0.8147 0.9623 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H12 mock treatment 0.346 0.0437 0.62 0.324 0.0586 0.98 1.1373 0.9759 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H13 mock treatment 0.371 0.0687 0.98 0.299 0.0336 0.56 1.0935 0.9654 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H14 mock treatment 0.379 0.0767 1.1 0.343 0.0776 1.3 1.6966 0.9963 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H15 mock treatment 0.432 0.13 1.85 0.435 0.17 2.85 3.3245 0.9784 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H16 mock treatment 0.388 0.0857 1.23 0.338 0.0726 1.22 1.7283 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H17 mock treatment 0.453 0.151 2.16 0.449 0.184 3.08 3.703 0.9847 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H18 mock treatment 0.347 0.0447 0.64 0.319 0.0536 0.9 1.0881 0.9859 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H19 mock treatment 0.365 0.0627 0.9 0.321 0.0556 0.93 1.2939 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H20 mock treatment 0.385 0.0827 1.18 0.297 0.0316 0.53 1.2113 0.9347 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H21 mock treatment 0.396 0.0937 1.34 0.326 0.0606 1.02 1.6667 0.9908 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H22 mock treatment 0.349 0.0467 0.67 0.321 0.0556 0.93 1.132 0.9865 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H23 mock treatment 0.254 -0.0483 -0.69 0.21 -0.0554 -0.93 -1.1462 -0.9894 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 H24 mock treatment 0.227 -0.0753 -1.08 0.27 0.00462 0.08 -0.7072 -0.6545 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I01 compound treatment 0.23 -0.0723 -1.03 0.193 -0.0724 -1.21 -1.5907 -0.9968 3178995 Maybridge4_004661 FC(F)(F)COc1ccc(cn1)C(=O)NC(=O)NN2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I02 compound treatment 0.261 -0.0413 -0.59 0.218 -0.0474 -0.8 -0.9804 -0.9894 3065824 Maybridge4_004662 Oc1nnc(SCc2cc(=O)oc3cc(O)ccc23)n1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I03 compound treatment 0.259 -0.0433 -0.62 0.227 -0.0384 -0.64 -0.8938 -0.9998 3178996 Maybridge4_004663 Cc1noc(COc2ccccc2)c1C(=O)Sc3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I04 compound treatment 0.276 -0.0263 -0.38 0.239 -0.0264 -0.44 -0.5795 -0.9968 3065825 Maybridge4_004664 Cc1c(C#N)c(Sc2ccccc2Cl)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I05 compound treatment 0.271 -0.0313 -0.45 0.24 -0.0254 -0.43 -0.6182 -0.9997 3178997 Maybridge4_004665 COC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)Nc3ccc(Cl)cc3)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I06 compound treatment 0.294 -0.00834 -0.12 0.258 -0.00738 -0.12 -0.1719 -0.9998 1622413 Maybridge4_004666 COc1ccc(SC(=O)c2cc(C)n(Cc3c(Cl)cccc3Cl)n2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I07 compound treatment 0.28 -0.0223 -0.32 0.285 0.0196 0.33 0.0069 0.015 3178998 Maybridge4_004667 FC(F)(F)c1ccc(=O)n(CC(=O)c2ccc(C#N)cc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I08 compound treatment 0.271 -0.0313 -0.45 0.28 0.0146 0.25 -0.1435 -0.2807 3065827 Maybridge4_004668 CSc1n[nH]c(=O)n1c2ccc3OCCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I09 compound treatment 0.046 -0.256 -3.67 0.048 -0.217 -3.65 -5.1726 -1.0 3065847 Maybridge4_004669 CCOC(=O)c1cc(C#N)c(Sc2n[nH]c(=O)n2Cc3ccc(cc3)C(F)(F)F)nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I10 compound treatment 0.312 0.00966 0.14 0.304 0.0386 0.65 0.5561 0.839 3065848 Maybridge4_004670 CC(C)(C)NC(=O)[C@H]1C[C@H]2CCCC[C@H]2CN1C(=O)C3(CC4CC5CC(C4)C3)C5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I11 compound treatment 0.311 0.00866 0.12 0.31 0.0446 0.75 0.6171 0.813 3065849 Maybridge4_004671 FC(F)(F)c1ccc(nc1)C(=N)NC(=O)c2ccc(Cl)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I12 compound treatment 0.279 -0.0233 -0.33 0.237 -0.0284 -0.48 -0.5729 -0.9849 1418931 Maybridge4_004672 Cc1cc(C)c(Cn2nc(cc2C(=O)NN3CCOCC3)C(C)(C)C)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I13 compound treatment 0.333 0.0307 0.44 0.303 0.0376 0.63 0.7566 0.9841 3065850 Maybridge4_004673 FC(F)(F)c1ccc(=O)n(Cc2cccc(c2)C(=O)NC(=N)c3ccc(Cl)cc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I14 compound treatment 0.3 -0.00234 -0.03 0.292 0.0266 0.45 0.2923 0.6523 1208016 Maybridge4_004674 COC(=O)[C@@H](NC(=O)c1cc(C)on1)C(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I15 compound treatment 0.301 -0.00134 -0.02 0.29 0.0246 0.41 0.2786 0.6736 1224162 Maybridge4_004675 CC(C)(C)C(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I16 compound treatment 0.327 0.0247 0.35 0.246 -0.0194 -0.33 0.0194 0.0405 3065852 Maybridge4_004676 CCN(C(=S)Nc1ccc(C)cc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I17 compound treatment 0.095 -0.207 -2.97 0.111 -0.154 -2.59 -3.9293 -0.9977 3178999 Maybridge4_004677 Clc1ccc(cc1)c2nnc(Sc3nc(ns3)c4cccs4)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I18 compound treatment 0.254 -0.0483 -0.69 0.253 -0.0124 -0.21 -0.6358 -0.8807 3065853 Maybridge4_004678 CCCNC(=O)Nc1nc(Nc2ccc(Cl)cc2)n[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I19 compound treatment 0.227 -0.0753 -1.08 0.239 -0.0264 -0.44 -1.0751 -0.9228 3179000 Maybridge4_004679 FC(F)(F)c1ccncc1C(=O)NC(=N)c2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I20 compound treatment 0.288 -0.0143 -0.21 0.271 0.00562 0.09 -0.0783 -0.347 3179001 Maybridge4_004680 CC(Sc1ccc(C)cc1)C(=O)Nc2ccc(cc2)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I21 compound treatment 0.229 -0.0733 -1.05 0.226 -0.0394 -0.66 -1.2091 -0.9752 3065854 Maybridge4_004681 Sc1nnc(s1)c2cnccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I22 mock treatment 0.292 -0.0103 -0.15 0.247 -0.0184 -0.31 -0.3227 -0.9433 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I23 mock treatment 0.213 -0.0893 -1.28 0.238 -0.0274 -0.46 -1.2285 -0.9047 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 I24 mock treatment 0.197 -0.105 -1.51 0.218 -0.0474 -0.8 -1.6277 -0.9554 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J01 mock treatment 0.404 0.102 1.45 0.426 0.161 2.7 2.9345 0.958 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J02 mock treatment 0.224 -0.0783 -1.12 0.242 -0.0234 -0.39 -1.0698 -0.9011 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J03 mock treatment 0.282 -0.0203 -0.29 0.261 -0.00438 -0.07 -0.2577 -0.8588 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J04 mock treatment 0.279 -0.0233 -0.33 0.236 -0.0294 -0.49 -0.5847 -0.9819 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J05 mock treatment 0.294 -0.00834 -0.12 0.277 0.0116 0.2 0.0536 0.2343 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J06 mock treatment 0.302 -3.39E-4 0.0 0.255 -0.0104 -0.17 -0.1266 -0.7265 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J07 mock treatment 0.313 0.0107 0.15 0.284 0.0186 0.31 0.3288 0.9456 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J08 mock treatment 0.322 0.0197 0.28 0.268 0.00262 0.04 0.2299 0.8078 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J09 mock treatment 0.324 0.0217 0.31 0.425 0.16 2.68 2.1135 0.7837 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J10 mock treatment 0.339 0.0367 0.52 0.309 0.0436 0.73 0.8885 0.9866 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J11 mock treatment 0.366 0.0637 0.91 0.275 0.00962 0.16 0.758 0.8197 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J12 mock treatment 0.379 0.0767 1.1 0.313 0.0476 0.8 1.3405 0.9879 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J13 mock treatment 0.348 0.0457 0.65 0.338 0.0726 1.22 1.3237 0.9572 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J14 mock treatment 0.336 0.0337 0.48 0.377 0.112 1.87 1.6652 0.8609 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J15 mock treatment 0.316 0.0137 0.2 0.314 0.0486 0.82 0.7152 0.8523 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J16 mock treatment 0.326 0.0237 0.34 0.349 0.0836 1.4 1.2317 0.8532 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J17 mock treatment 0.356 0.0537 0.77 0.323 0.0576 0.97 1.2266 0.9934 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J18 mock treatment 0.343 0.0407 0.58 0.349 0.0836 1.4 1.4037 0.9239 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J19 mock treatment 0.359 0.0567 0.81 0.349 0.0836 1.4 1.5655 0.9659 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J20 mock treatment 0.357 0.0547 0.78 0.359 0.0936 1.57 1.6639 0.9481 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J21 mock treatment 0.351 0.0487 0.7 0.393 0.128 2.14 2.0068 0.891 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J22 mock treatment 0.33 0.0277 0.4 0.347 0.0816 1.37 1.2484 0.8755 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J23 mock treatment 0.243 -0.0593 -0.85 0.283 0.0176 0.3 -0.3911 -0.4351 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 J24 mock treatment 0.225 -0.0773 -1.11 0.227 -0.0384 -0.64 -1.2377 -0.9669 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K01 compound treatment 0.325 0.0227 0.32 0.283 0.0176 0.3 0.4383 0.999 3065855 Maybridge4_004682 Oc1c/c(=N\c2ccc(Cl)cc2)/nc(COc3ccccc3)[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K02 compound treatment 0.246 -0.0563 -0.81 0.208 -0.0574 -0.96 -1.2508 -0.9961 3179002 Maybridge4_004683 Cc1cc(nn1C(C)(C)C)C(=O)Sc2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K03 compound treatment 0.286 -0.0163 -0.23 0.252 -0.0134 -0.22 -0.3241 -0.9998 3179003 Maybridge4_004684 Cc1noc(COc2ccccc2)c1C(=O)Sc3ccc(F)cc3F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K04 compound treatment 0.272 -0.0303 -0.43 0.302 0.0366 0.61 0.1277 0.1698 3065857 Maybridge4_004685 Cc1c(C#N)c(Sc2cccc(c2)C(F)(F)F)nc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K05 compound treatment 0.288 -0.0143 -0.21 0.229 -0.0364 -0.61 -0.5768 -0.8955 3179004 Maybridge4_004686 CSc1nc(CSc2ccc(Cl)cc2)nc(C3CC3)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K06 compound treatment 0.325 0.0227 0.32 0.256 -0.00938 -0.16 0.1179 0.3271 3065858 Maybridge4_004687 Cc1cc(nn1Cc2c(Cl)cccc2Cl)C(=O)SCc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K07 compound treatment 0.276 -0.0263 -0.38 0.28 0.0146 0.25 -0.0929 -0.2066 3179005 Maybridge4_004688 CCOC(=O)c1cc(C#N)c(Oc2ccc(C)cc2)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K08 compound treatment 0.182 -0.12 -1.72 0.259 -0.00638 -0.11 -1.2929 -0.7497 3065859 Maybridge4_004689 CC(C)OC(=O)Nc1cc(Cl)cc(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K09 compound treatment 0.278 -0.0243 -0.35 0.265 -3.81E-4 -0.01 -0.2507 -0.72 3179006 Maybridge4_004690 FC(F)(F)C1CCN(CC1)c2ncccc2NC(=S)Nc3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K10 compound treatment 0.271 -0.0313 -0.45 0.278 0.0126 0.21 -0.1672 -0.3372 1235731 Maybridge4_004691 S=C(NC1CCCC1)N2CCCN(CC2)c3ccc(C#N)cn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K11 compound treatment 0.306 0.00366 0.05 0.265 -3.81E-4 -0.01 0.0325 0.6163 3179007 Maybridge4_004692 FC(F)(F)c1ccc(nc1)C(=N)NC(=O)c2cccc(c2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K12 compound treatment 0.267 -0.0353 -0.51 0.256 -0.00938 -0.16 -0.4688 -0.8854 1285775 Maybridge4_004693 Cc1onc(c1c2csc(CCn3c(=O)oc4ccccc34)n2)c5c(Cl)cccc5Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K13 compound treatment 0.258 -0.0443 -0.63 0.297 0.0316 0.53 -0.0732 -0.0885 3065861 Maybridge4_004694 NNC(=O)c1cccc(n1)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K14 compound treatment 0.296 -0.00634 -0.09 0.27 0.00462 0.08 -0.0093 -0.0779 3179092 Maybridge4_004695 CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCN3CCOCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K15 compound treatment 0.221 -0.0813 -1.16 0.217 -0.0484 -0.81 -1.3969 -0.9845 3065862 Maybridge4_004696 FC(F)(F)c1ccc(nc1)c2nnc(S)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K16 compound treatment 0.255 -0.0473 -0.68 0.309 0.0436 0.73 0.0389 0.039 3065863 Maybridge4_004697 CC(C)N(CCC#N)C(=S)Nc1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K17 compound treatment 0.276 -0.0263 -0.38 0.231 -0.0344 -0.58 -0.6744 -0.9787 3179093 Maybridge4_004698 CC(C)C(=N)NC(=S)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K18 compound treatment 0.275 -0.0273 -0.39 0.227 -0.0384 -0.64 -0.732 -0.9714 1330597 Maybridge4_004699 CS(=O)(=O)c1ccc(cc1)C(=O)Nc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K19 compound treatment 0.239 -0.0633 -0.91 0.226 -0.0394 -0.66 -1.108 -0.988 3179094 Maybridge4_004700 N=C(NC(=O)N1CCOCC1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K20 compound treatment 0.248 -0.0543 -0.78 0.206 -0.0594 -1.0 -1.2543 -0.9924 3065864 Maybridge4_004701 CN(C)/C=N/c1ncc(Br)cc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K21 compound treatment 0.255 -0.0473 -0.68 0.261 -0.00438 -0.07 -0.5308 -0.7793 3179095 Maybridge4_004702 CC(C)(C)C(=O)CSc1nnc(s1)c2cnccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K22 mock treatment 0.313 0.0107 0.15 0.306 0.0406 0.68 0.5899 0.8444 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K23 mock treatment 0.223 -0.0793 -1.13 0.257 -0.00838 -0.14 -0.9019 -0.7887 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 K24 mock treatment 0.248 -0.0543 -0.78 0.23 -0.0354 -0.59 -0.9695 -0.9912 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L01 mock treatment 0.246 -0.0563 -0.81 0.431 0.166 2.78 1.3958 0.4823 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L02 mock treatment 0.264 -0.0383 -0.55 0.246 -0.0194 -0.33 -0.6178 -0.9689 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L03 mock treatment 0.412 0.11 1.57 0.404 0.139 2.33 2.7543 0.9816 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L04 mock treatment 0.285 -0.0173 -0.25 0.237 -0.0284 -0.48 -0.5122 -0.9537 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L05 mock treatment 0.28 -0.0223 -0.32 0.223 -0.0424 -0.71 -0.7289 -0.9348 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L06 mock treatment 0.333 0.0307 0.44 0.257 -0.00838 -0.14 0.2107 0.4574 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L07 mock treatment 0.335 0.0327 0.47 0.258 -0.00738 -0.12 0.2427 0.5023 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L08 mock treatment 0.333 0.0307 0.44 0.27 0.00462 0.08 0.3649 0.8194 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L09 mock treatment 0.286 -0.0163 -0.23 0.256 -0.00938 -0.16 -0.2766 -0.9815 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L10 mock treatment 0.333 0.0307 0.44 0.29 0.0246 0.41 0.6023 0.9996 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L11 mock treatment 0.273 -0.0293 -0.42 0.252 -0.0134 -0.22 -0.4555 -0.9571 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L12 mock treatment 0.285 -0.0173 -0.25 0.292 0.0266 0.45 0.1406 0.2751 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L13 mock treatment 0.302 -3.39E-4 0.0 0.309 0.0436 0.73 0.5143 0.7024 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L14 mock treatment 0.337 0.0347 0.5 0.309 0.0436 0.73 0.8683 0.982 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L15 mock treatment 0.341 0.0387 0.55 0.267 0.00162 0.03 0.4102 0.741 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L16 mock treatment 0.311 0.00866 0.12 0.318 0.0526 0.88 0.7121 0.7985 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L17 mock treatment 0.332 0.0297 0.42 0.294 0.0286 0.48 0.6397 0.9981 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L18 mock treatment 0.308 0.00566 0.08 0.289 0.0236 0.4 0.3376 0.8343 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L19 mock treatment 0.311 0.00866 0.12 0.325 0.0596 1.0 0.7952 0.7886 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L20 mock treatment 0.415 0.113 1.61 0.424 0.159 2.66 3.022 0.9711 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L21 mock treatment 0.375 0.0727 1.04 0.376 0.111 1.86 2.0478 0.9624 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L22 mock treatment 0.327 0.0247 0.35 0.417 0.152 2.54 2.0489 0.7975 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L23 mock treatment 0.28 -0.0223 -0.32 0.265 -3.81E-4 -0.01 -0.2305 -0.7211 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 L24 mock treatment 0.306 0.00366 0.05 0.199 -0.0664 -1.11 -0.7508 -0.6731 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M01 compound treatment 0.265 -0.0373 -0.53 0.335 0.0696 1.17 0.4486 0.3492 3065865 Maybridge4_004703 FC(F)(F)c1cccn(CCc2nc(cs2)c3ccccc3)c1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M02 compound treatment 0.295 -0.00734 -0.1 0.27 0.00462 0.08 -0.0194 -0.1487 3179096 Maybridge4_004704 Cc1cc(nn1C(C)(C)C)C(=O)Sc2cccc(Br)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M03 compound treatment 0.281 -0.0213 -0.31 0.248 -0.0174 -0.29 -0.4221 -0.9997 3179097 Maybridge4_004705 CN(CCOC(=O)c1ccc(Cl)cc1)c2ncc(cc2Cl)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M04 compound treatment 0.286 -0.0163 -0.23 0.237 -0.0284 -0.48 -0.5021 -0.9463 3065866 Maybridge4_004706 Cc1c(C#N)c(Sc2n[nH]c(=O)n2C3CCCCC3)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M05 compound treatment 0.25 -0.0523 -0.75 0.285 0.0196 0.33 -0.2965 -0.3626 3065894 Maybridge4_004707 CCOC(=O)c1cc(C)nc(Sc2ccccc2NC(=O)c3cccc(c3)C(F)(F)F)c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M06 compound treatment 0.313 0.0107 0.15 0.316 0.0506 0.85 0.7086 0.8209 3065895 Maybridge4_004708 OC(C(O)c1nc2cc(C#N)ccc2[nH]1)c3nc4cc(C#N)ccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M07 compound treatment 0.316 0.0137 0.2 0.29 0.0246 0.41 0.4304 0.9415 3065896 Maybridge4_004709 CCOC(=O)c1cc(C#N)c(Sc2nnc([nH]2)C(C)(C)C)nc1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M08 compound treatment 0.281 -0.0213 -0.31 0.274 0.00862 0.14 -0.1135 -0.3361 3065897 Maybridge4_004710 NC(=S)Cc1ccc(Cl)cc1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M09 compound treatment 0.2 -0.102 -1.46 0.183 -0.0824 -1.38 -2.0128 -0.9996 3065898 Maybridge4_004711 FC(F)(F)C1CCN(CC1)c2ncccc2NC(=S)Nc3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M10 compound treatment 0.232 -0.0703 -1.01 0.261 -0.00438 -0.07 -0.7634 -0.7568 1643927 Maybridge4_004712 CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)c2nnc(S)n2CC3CCCO3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M11 compound treatment 0.25 -0.0523 -0.75 0.237 -0.0284 -0.48 -0.8662 -0.9762 3065900 Maybridge4_004713 FC(F)(F)c1ccc(=O)n(Cc2cccc(C#N)c2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M12 compound treatment 0.288 -0.0143 -0.21 0.3 0.0346 0.58 0.2658 0.4314 1263587 Maybridge4_004714 COc1ccccc1OCc2nc(cs2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M13 compound treatment 0.294 -0.00834 -0.12 0.304 0.0386 0.65 0.374 0.5675 3179098 Maybridge4_004715 FC(F)(F)c1ccc(cc1)C(=N)NC(=O)CCn2c(=O)oc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M14 compound treatment 0.276 -0.0263 -0.38 0.25 -0.0154 -0.26 -0.4489 -0.983 1136340 Maybridge4_004716 CCOc1cc(N2CCOCC2)c(OCC)cc1NS(=O)(=O)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M15 compound treatment 0.302 -3.39E-4 0.0 0.261 -0.00438 -0.07 -0.0554 -0.7521 3179099 Maybridge4_004717 FC(F)(F)c1ccc(nc1)c2nnc(SCC=C)s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M16 compound treatment 0.29 -0.0123 -0.18 0.249 -0.0164 -0.27 -0.3192 -0.977 1122167 Maybridge4_004718 O=C(N1CCN(CCOc2ccccc2)CC1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M17 compound treatment 0.263 -0.0393 -0.56 0.242 -0.0234 -0.39 -0.6754 -0.9845 3179100 Maybridge4_004719 FC(F)(F)COc1ccc(cn1)C(=O)NC(=N)c2ccc(cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M18 compound treatment 0.248 -0.0543 -0.78 0.248 -0.0174 -0.29 -0.7559 -0.9105 3065901 Maybridge4_004720 CNC(=O)Nc1nc2cccnc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M19 compound treatment 0.301 -0.00134 -0.02 0.298 0.0326 0.55 0.3736 0.682 1030287 Maybridge4_004721 CSc1nc(O)cc(O)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M20 compound treatment 0.222 -0.0803 -1.15 0.27 0.00462 0.08 -0.7577 -0.6579 3179101 Maybridge4_004722 Cc1nc(N/C=N/O)c(Br)cc1Br 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M21 compound treatment 0.297 -0.00534 -0.08 0.253 -0.0124 -0.21 -0.2009 -0.9076 3179102 Maybridge4_004723 Cc1nc(c(s1)C(=O)Sc2ccc(C)cc2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M22 mock treatment 0.287 -0.0153 -0.22 0.305 0.0396 0.66 0.3151 0.4499 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M23 mock treatment 0.266 -0.0363 -0.52 0.297 0.0316 0.53 0.0077 0.0104 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 M24 mock treatment 0.219 -0.0833 -1.19 0.216 -0.0494 -0.83 -1.429 -0.9842 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N01 mock treatment 0.452 0.15 2.14 0.448 0.183 3.07 3.6811 0.9846 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N02 mock treatment 0.433 0.131 1.87 0.423 0.158 2.65 3.1922 0.9855 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N03 mock treatment 0.261 -0.0413 -0.59 0.209 -0.0564 -0.95 -1.0872 -0.9744 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N04 mock treatment 0.258 -0.0443 -0.63 0.248 -0.0174 -0.29 -0.6547 -0.9379 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N05 mock treatment 0.341 0.0387 0.55 0.26 -0.00538 -0.09 0.3272 0.5839 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N06 mock treatment 0.29 -0.0123 -0.18 0.283 0.0176 0.3 0.0843 0.2448 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N07 mock treatment 0.308 0.00566 0.08 0.214 -0.0514 -0.86 -0.5525 -0.6379 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N08 mock treatment 0.447 0.145 2.07 0.438 0.173 2.9 3.5118 0.9864 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N09 mock treatment 0.295 -0.00734 -0.1 0.248 -0.0174 -0.29 -0.2805 -0.9048 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N10 mock treatment 0.446 0.144 2.05 0.441 0.176 2.95 3.5373 0.9844 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N11 mock treatment 0.452 0.15 2.14 0.457 0.192 3.22 3.7879 0.9804 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N12 mock treatment 0.311 0.00866 0.12 0.294 0.0286 0.48 0.4273 0.8613 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N13 mock treatment 0.45 0.148 2.11 0.447 0.182 3.05 3.649 0.9839 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N14 mock treatment 0.257 -0.0453 -0.65 0.298 0.0326 0.55 -0.0714 -0.0842 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N15 mock treatment 0.44 0.138 1.97 0.446 0.181 3.03 3.5359 0.9782 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N16 mock treatment 0.445 0.143 2.04 0.43 0.165 2.76 3.3966 0.9889 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N17 mock treatment 0.23 -0.0723 -1.03 0.241 -0.0244 -0.41 -1.021 -0.9176 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N18 mock treatment 0.236 -0.0663 -0.95 0.218 -0.0474 -0.8 -1.2333 -0.9961 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N19 mock treatment 0.341 0.0387 0.55 0.312 0.0466 0.78 0.9443 0.9856 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N20 mock treatment 0.434 0.132 1.88 0.435 0.17 2.85 3.3447 0.9799 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N21 mock treatment 0.327 0.0247 0.35 0.227 -0.0384 -0.64 -0.2061 -0.2806 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N22 mock treatment 0.303 6.61E-4 0.01 0.267 0.00162 0.03 0.0259 0.9002 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N23 mock treatment 0.238 -0.0643 -0.92 0.27 0.00462 0.08 -0.5959 -0.6452 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 N24 mock treatment 0.25 -0.0523 -0.75 0.237 -0.0284 -0.48 -0.8662 -0.9762 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O01 compound treatment 0.266 -0.0363 -0.52 0.242 -0.0234 -0.39 -0.645 -0.9904 3065902 Maybridge4_004724 Cc1nn(c(N)c1C(=S)N)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O02 compound treatment 0.267 -0.0353 -0.51 0.276 0.0106 0.18 -0.2314 -0.4317 1470895 Maybridge4_004725 CCOC(=O)c1cc(Sc2ccccc2NC(=O)c3ccccc3)cc(n1)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O03 compound treatment 0.31 0.00766 0.11 0.231 -0.0344 -0.58 -0.3305 -0.5628 3065903 Maybridge4_004726 Cc1cc(no1)c2nnc(SCC(=O)c3ccccc3Cl)n2C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O04 compound treatment 0.299 -0.00334 -0.05 0.254 -0.0114 -0.19 -0.1688 -0.8575 1417512 Maybridge4_004727 Cc1c(C#N)c(Sc2ccccc2NC(=O)c3ccccc3)nc4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O05 compound treatment 0.243 -0.0593 -0.85 0.264 -0.00138 -0.02 -0.6166 -0.7261 3065905 Maybridge4_004728 CC(C)(C)c1ccc(OCC(=N)NC(=O)c2ccc(OC(F)(F)F)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O06 compound treatment 0.261 -0.0413 -0.59 0.189 -0.0764 -1.28 -1.3246 -0.9383 1176898 Maybridge4_004729 OC(C(O)c1nc2cc(Cl)ccc2[nH]1)c3nc4cc(Cl)ccc4[nH]3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O07 compound treatment 0.227 -0.0753 -1.08 0.217 -0.0484 -0.81 -1.3362 -0.9903 3065906 Maybridge4_004730 Cc1nc(nc(Sc2nnc([nH]2)c3cccs3)c1C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O08 compound treatment 0.254 -0.0483 -0.69 0.234 -0.0314 -0.53 -0.8613 -0.991 3179103 Maybridge4_004731 CC(=O)N/C(=C\c1ccc2ccccc2c1)/C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O09 compound treatment 0.281 -0.0213 -0.31 0.228 -0.0374 -0.63 -0.6595 -0.9452 3179104 Maybridge4_004732 NC(=O)C1=CN(Cc2ccccc2)CCC1C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O10 compound treatment 0.287 -0.0153 -0.22 0.243 -0.0224 -0.38 -0.4208 -0.9672 3065908 Maybridge4_004733 CC(C)(C)c1cc(c2nnc(o2)c3cccs3)n(Cc4ccc(F)cc4)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O11 compound treatment 0.244 -0.0583 -0.83 0.205 -0.0604 -1.01 -1.3067 -0.9953 3179105 Maybridge4_004734 FC(F)(F)COc1cc(cc(OCC(F)(F)F)n1)c2nnc(S)n2Cc3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O12 compound treatment 0.072 -0.23 -3.29 0.092 -0.173 -2.91 -4.3874 -0.9981 3065960 Maybridge4_004735 Clc1ccc(Sc2c[nH]nc2c3ccc4OCCOc4c3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O13 compound treatment 0.238 -0.0643 -0.92 0.229 -0.0364 -0.61 -1.0825 -0.9801 1741446 Maybridge4_004736 CC(C)(C)NC(=O)N1CCN(CC1)c2ccc(C#N)cn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O14 compound treatment 0.242 -0.0603 -0.86 0.229 -0.0364 -0.61 -1.042 -0.9856 1571449 Maybridge4_004737 CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O15 compound treatment 0.276 -0.0263 -0.38 0.239 -0.0264 -0.44 -0.5795 -0.9968 3065932 Maybridge4_004738 N/C(=N\O)/c1ccc(Cl)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O16 compound treatment 0.231 -0.0713 -1.02 0.227 -0.0384 -0.64 -1.177 -0.9754 1468379 Maybridge4_004739 CC(C)c1ccc(NC(=O)N2CCCN(CCOc3ccccc3)CC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O17 compound treatment 0.233 -0.0693 -0.99 0.19 -0.0754 -1.27 -1.5959 -0.9927 3065933 Maybridge4_004740 COc1ccc(OCC(=N)NC(=S)Nc2cccc(c2)C(F)(F)F)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O18 compound treatment 0.231 -0.0713 -1.02 0.211 -0.0544 -0.91 -1.3669 -0.9985 3065934 Maybridge4_004741 NC(=C(C#N)C#N)Nc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O19 compound treatment 0.24 -0.0623 -0.89 0.238 -0.0274 -0.46 -0.9555 -0.9525 3065935 Maybridge4_004742 Oc1nnc(SCC(=O)N2CCC(CC2)C(F)(F)F)n1c3cccc(c3)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O20 compound treatment 0.26 -0.0423 -0.61 0.207 -0.0584 -0.98 -1.1211 -0.9733 3065936 Maybridge4_004743 Cc1cc(Br)cnc1N/C=N/O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O21 compound treatment 0.225 -0.0773 -1.11 0.209 -0.0564 -0.95 -1.4514 -0.997 3179106 Maybridge4_004744 Cc1nc(c(s1)C(=O)Sc2cccc(c2)C(F)(F)F)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O22 mock treatment 0.238 -0.0643 -0.92 0.21 -0.0554 -0.93 -1.308 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O23 mock treatment 0.209 -0.0933 -1.34 0.236 -0.0294 -0.49 -1.2927 -0.9083 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 O24 mock treatment 0.206 -0.0963 -1.38 0.254 -0.0114 -0.19 -1.1095 -0.7975 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P01 mock treatment 0.439 0.137 1.95 0.446 0.181 3.03 3.5258 0.9775 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P02 mock treatment 0.449 0.147 2.1 0.445 0.18 3.01 3.6151 0.9843 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P03 mock treatment 0.244 -0.0583 -0.83 0.234 -0.0314 -0.53 -0.9625 -0.9754 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P04 mock treatment 0.26 -0.0423 -0.61 0.255 -0.0104 -0.17 -0.5514 -0.875 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P05 mock treatment 0.246 -0.0563 -0.81 0.238 -0.0274 -0.46 -0.8948 -0.9645 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P06 mock treatment 0.248 -0.0543 -0.78 0.24 -0.0254 -0.43 -0.8508 -0.9599 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P07 mock treatment 0.451 0.149 2.13 0.438 0.173 2.9 3.5523 0.9884 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P08 mock treatment 0.219 -0.0833 -1.19 0.252 -0.0134 -0.22 -1.0017 -0.8258 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P09 mock treatment 0.256 -0.0463 -0.66 0.253 -0.0124 -0.21 -0.6156 -0.8863 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P10 mock treatment 0.433 0.131 1.87 0.248 -0.0174 -0.29 1.1153 0.5896 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P11 mock treatment 0.45 0.148 2.11 0.443 0.178 2.98 3.6015 0.9858 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P12 mock treatment 0.444 0.142 2.03 0.244 -0.0214 -0.36 1.179 0.573 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P13 mock treatment 0.297 -0.00534 -0.08 0.299 0.0336 0.56 0.345 0.6059 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P14 mock treatment 0.449 0.147 2.1 0.429 0.164 2.75 3.4252 0.9912 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P15 mock treatment 0.251 -0.0513 -0.73 0.255 -0.0104 -0.17 -0.6425 -0.8512 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P16 mock treatment 0.454 0.152 2.17 0.451 0.186 3.12 3.7369 0.9843 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P17 mock treatment 0.456 0.154 2.2 0.456 0.191 3.2 3.8165 0.9832 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P18 mock treatment 0.451 0.149 2.13 0.454 0.189 3.17 3.7421 0.9813 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P19 mock treatment 0.446 0.144 2.05 0.438 0.173 2.9 3.5017 0.9858 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P20 mock treatment 0.437 0.135 1.93 0.431 0.166 2.78 3.3276 0.9839 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P21 mock treatment 0.441 0.139 1.98 0.448 0.183 3.07 3.5698 0.9778 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P22 mock treatment 0.448 0.146 2.08 0.442 0.177 2.96 3.5694 0.9851 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P23 mock treatment 0.271 -0.0313 -0.45 0.262 -0.00338 -0.06 -0.3571 -0.7903 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2062 P24 mock treatment 0.223 -0.0793 -1.13 0.246 -0.0194 -0.33 -1.0325 -0.8746 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A01 compound treatment 0.257 0.0106 0.15 0.234 -0.00872 -0.15 0.0034 0.016 1360118 TimTec1_000001 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccncc4)C(=O)OC5CCCC5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A02 compound treatment 0.323 0.0766 1.1 0.331 0.0883 1.48 1.8221 0.9889 1352805 TimTec1_000002 CCOC(=O)c1cc2ccccc2oc1=N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A03 compound treatment 0.262 0.0156 0.22 0.303 0.0603 1.01 0.8728 0.8425 1269647 TimTec1_000003 CN1C2CCC1CC(C2)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A04 compound treatment 0.23 -0.0164 -0.24 0.246 0.00328 0.06 -0.1273 -0.5272 1717432 TimTec1_000004 NC1=C(C#N)C2=C(CCCC2)C(c3ccccc3)C1(C#N)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A05 compound treatment 0.253 0.00656 0.09 0.245 0.00228 0.04 0.0934 0.9218 1640292 TimTec1_000005 CC1C2CC(C(C2=O)S(=O)(=O)N3CCOCC3)C1(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A06 compound treatment 0.261 0.0146 0.21 0.231 -0.0117 -0.2 0.0082 0.0287 1432692 TimTec1_000006 CC(=C)C[N+](C)(C)Cc1c(C)ccc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A07 compound treatment 0.277 0.0306 0.44 0.297 0.0543 0.91 0.9533 0.9434 3209477 TimTec1_000007 O=C1N(CSc2nc3ccccc3s2)C(=O)c4ccccc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A08 compound treatment 0.22 -0.0264 -0.38 0.239 -0.00372 -0.06 -0.3115 -0.8128 1665724 TimTec1_000008 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3ccccc3)C(=O)C1)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A09 compound treatment 0.239 -0.00744 -0.11 0.26 0.0173 0.29 0.1299 0.4204 1568897 TimTec1_000009 CCOC(=O)c1ccc(NC(=O)NC2OC(CO)C(O)C(O)C2O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A10 compound treatment 0.217 -0.0294 -0.42 0.231 -0.0117 -0.2 -0.4368 -0.9399 3082080 TimTec1_000010 Cc1cc[n+](Cc2ccccn2)c(N)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A11 compound treatment 0.221 -0.0254 -0.36 0.223 -0.0197 -0.33 -0.4913 -0.9989 1782663 TimTec1_000011 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3NC2/C=C/c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A12 compound treatment 0.231 -0.0154 -0.22 0.221 -0.0217 -0.36 -0.4139 -0.9712 3082082 TimTec1_000012 CCCC1CCCCCC1NC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A13 compound treatment 0.206 -0.0404 -0.58 0.196 -0.0467 -0.78 -0.9635 -0.9888 3508726 TimTec1_000013 CCC(=O)NC1CC(CC=C1C)C(C)(C)NC(=O)CC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A14 compound treatment 0.196 -0.0504 -0.72 0.203 -0.0397 -0.67 -0.9815 -0.9992 3209587 TimTec1_000014 OC(=O)CCC(=O)N=S(c1ccccc1)c2ccccc2.Oc1c(cc(cc1[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-] 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A15 compound treatment 0.26 0.0136 0.19 0.217 -0.0257 -0.43 -0.1681 -0.3551 1459520 TimTec1_000015 COc1ccccc1c2nnc(N)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A16 compound treatment 0.219 -0.0274 -0.39 0.06 -0.183 -3.07 -2.446 -0.7911 3082084 TimTec1_000016 Cc1[nH]c2ccccc2c1Sc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A17 compound treatment 0.192 -0.0544 -0.78 0.187 -0.0557 -0.94 -1.2119 -0.9959 1172294 TimTec1_000017 Cc1cc(C)c(NC(=O)CCNC2CCCCC2)c(C)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A18 compound treatment 0.201 -0.0454 -0.65 0.225 -0.0177 -0.3 -0.6699 -0.9372 1183562 TimTec1_000018 CCOC(=O)c1c(CN2CCOCC2)n(c3ccccc3)c4ccc(O)cc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A19 compound treatment 0.255 0.00856 0.12 0.214 -0.0287 -0.48 -0.2542 -0.5112 1230606 TimTec1_000019 CCN1CCN(CC1)c2ccc(NC(=O)c3cccc(Br)c3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A20 compound treatment 0.232 -0.0144 -0.21 0.218 -0.0247 -0.41 -0.4394 -0.9481 1045901 TimTec1_000020 COC(=O)c1cc2ccccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A21 compound treatment 0.234 -0.0124 -0.18 0.248 0.00528 0.09 -0.0631 -0.3176 3209588 TimTec1_000021 CSc1ccc(/C=N/n2nnnc2Nc3ccccc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A22 compound treatment 0.254 0.00756 0.11 0.269 0.0263 0.44 0.3884 0.8552 3082088 TimTec1_000022 OC(=O)CSc1c([nH]c2ccccc12)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A23 mock treatment 0.227 -0.0194 -0.28 0.207 -0.0357 -0.6 -0.6205 -0.939 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 A24 mock treatment 0.202 -0.0444 -0.64 0.228 -0.0147 -0.25 -0.6241 -0.9152 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B01 compound treatment 0.25 0.00356 0.05 0.253 0.0103 0.17 0.1581 0.8784 1462495 TimTec1_000023 CSc1c(CC(=O)Nc2ccccc2)n(C)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B02 compound treatment 0.197 -0.0494 -0.71 0.226 -0.0167 -0.28 -0.6984 -0.9181 3209589 TimTec1_000024 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B03 compound treatment 0.205 -0.0414 -0.59 0.224 -0.0187 -0.31 -0.6413 -0.9559 1291339 TimTec1_000025 CCOC(=O)c1c(CN2CCOCC2)n(C)c3ccc(O)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B04 compound treatment 0.21 -0.0364 -0.52 0.238 -0.00472 -0.08 -0.4245 -0.8053 1292419 TimTec1_000026 O=C(Oc1ccc(OC(=O)c2ccco2)cc1)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B05 compound treatment 0.221 -0.0254 -0.36 0.232 -0.0107 -0.18 -0.3845 -0.9473 1346277 TimTec1_000027 O=C(N1CCCCC1)c2ccc(cc2)C(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B06 compound treatment 0.238 -0.00844 -0.12 0.222 -0.0207 -0.35 -0.3312 -0.8999 1037513 TimTec1_000028 O=C1N(C(=O)c2ccccc12)c3nccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B07 compound treatment 0.216 -0.0304 -0.44 0.203 -0.0397 -0.67 -0.7792 -0.9787 3209590 TimTec1_000029 Cc1ccc(s1)C(=O)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B08 compound treatment 0.235 -0.0114 -0.16 0.2 -0.0427 -0.72 -0.6227 -0.8467 1598558 TimTec1_000030 O=C(Nc1ccccc1)C(=S)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B09 compound treatment 0.206 -0.0404 -0.58 0.194 -0.0487 -0.82 -0.9872 -0.9856 1166367 TimTec1_000031 CCOC(=O)c1c(CN2CCCCC2)n(c3ccccc3)c4cc(Br)c(OC)cc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B10 compound treatment 0.213 -0.0334 -0.48 0.22 -0.0227 -0.38 -0.6078 -0.9937 3081103 TimTec1_000032 C/C(=N\C1CC1)/c2c(C)[nH]n(c3nc4ccccc4s3)c2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B11 compound treatment 0.224 -0.0224 -0.32 0.194 -0.0487 -0.82 -0.8051 -0.9166 1692568 TimTec1_000033 Fc1ccc(cc1)C(=O)CCCN2CCNCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B12 compound treatment 0.22 -0.0264 -0.38 0.22 -0.0227 -0.38 -0.537 -1.0 3209591 TimTec1_000034 CCN1C(=O)/C(=C\2/C=Cc3ccccc3N2CC)/N(C)C1=S 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B13 compound treatment 0.279 0.0326 0.47 0.203 -0.0397 -0.67 -0.142 -0.1747 1611433 TimTec1_000035 CC(=O)Oc1ccc2occ(C(=O)c3ccc(Br)s3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B14 compound treatment 0.219 -0.0274 -0.39 0.224 -0.0187 -0.31 -0.4997 -0.9939 1351179 TimTec1_000036 O=C(c1nnn(c1Nc2ccccc2)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B15 compound treatment 0.24 -0.00644 -0.09 0.212 -0.0307 -0.52 -0.4297 -0.8204 1357665 TimTec1_000037 OC(=O)c1cccc(CN2CCN(CC2)c3ccccc3)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B16 compound treatment 0.254 0.00756 0.11 0.224 -0.0187 -0.31 -0.1457 -0.4384 1209399 TimTec1_000038 O=C(NCCc1ccccc1)c2ccc(cc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B17 compound treatment 0.22 -0.0264 -0.38 0.262 0.0193 0.32 -0.0386 -0.0775 3209592 TimTec1_000039 CNC(=O)CSCc1ccc(Br)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B18 compound treatment 0.216 -0.0304 -0.44 0.198 -0.0447 -0.75 -0.8386 -0.9664 3209593 TimTec1_000040 O=C(Oc1nc2ccccc2s1)/C=C/c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B19 compound treatment 0.236 -0.0104 -0.15 0.279 0.0363 0.61 0.325 0.5184 1421610 TimTec1_000041 CN(C(=O)Oc1cccc(c1)C(=O)Nc2ccc(C)c(C)c2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B20 compound treatment 0.211 -0.0354 -0.51 0.296 0.0533 0.89 0.2739 0.2665 3209594 TimTec1_000042 COC(=O)NC(Nc1cccc(c1)C(F)(F)F)C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B21 compound treatment 0.238 -0.00844 -0.12 0.237 -0.00572 -0.1 -0.1532 -0.9936 1920491 TimTec1_000043 COc1ccc2nc(NC(=N)N)nc(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B22 compound treatment 0.334 0.0876 1.25 0.313 0.0703 1.18 1.7197 0.9996 1644751 TimTec1_000044 COc1ccc(cc1)C(=O)Oc2csc(=S)n2C(=O)c3ccc(OC)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B23 mock treatment 0.332 0.0856 1.22 0.249 0.00628 0.11 0.9399 0.7652 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 B24 mock treatment 0.25 0.00356 0.05 0.285 0.0423 0.71 0.5378 0.7559 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C01 compound treatment 0.244 -0.00244 -0.03 0.278 0.0353 0.59 0.3941 0.6643 1157703 TimTec1_000045 COc1ccc2C3CC(=Nc4ccccc4N3C(=O)c2c1OC)c5ccc(Br)cc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C02 compound treatment 0.208 -0.0384 -0.55 0.271 0.0283 0.47 -0.0531 -0.0731 3209595 TimTec1_000046 COC(=O)CC1=CC(C)(CC(=O)OC)C(C#N)(C#N)C(=C1C#N)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C03 compound treatment 0.266 0.0196 0.28 0.231 -0.0117 -0.2 0.0588 0.1719 1704164 TimTec1_000047 CCCCN(C1CC2CCC(C1)N2C)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C04 compound treatment 0.267 0.0206 0.29 0.248 0.00528 0.09 0.2707 0.8811 1258841 TimTec1_000048 O=C1C(=C2CCCCC2C(c3ccco3)C1(C#N)C#N)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C05 compound treatment 0.21 -0.0364 -0.52 0.255 0.0123 0.21 -0.2228 -0.3975 1916777 TimTec1_000049 CC1C/2CC(C(\C2=N\O)S(=O)(=O)N3CCOCC3)C1(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C06 compound treatment 0.249 0.00256 0.04 0.226 -0.0167 -0.28 -0.1725 -0.6096 3209596 TimTec1_000050 COC1OC(COC(=O)C)C(OC(=O)C)C(C#N)(C#N)C1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C07 compound treatment 0.201 -0.0454 -0.65 0.264 0.0213 0.36 -0.207 -0.2791 1250478 TimTec1_000051 OC(COc1ccc(Nc2ccccc2)cc1)COc3ccc(Nc4ccccc4)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C08 compound treatment 0.21 -0.0364 -0.52 0.254 0.0113 0.19 -0.2347 -0.4232 1606069 TimTec1_000052 CC(C)C(C1C(=O)CC(C)(C)CC1=O)C2=C(O)CC(C)(C)CC2=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C09 compound treatment 0.222 -0.0244 -0.35 0.207 -0.0357 -0.6 -0.6711 -0.967 3081440 TimTec1_000053 CCNC(=O)c1ccc(Cl)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C10 compound treatment 0.199 -0.0474 -0.68 0.217 -0.0257 -0.43 -0.785 -0.9762 3209597 TimTec1_000054 Cc1cc[n+](CCOc2ccc(N)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C11 compound treatment 0.261 0.0146 0.21 0.176 -0.0667 -1.12 -0.6445 -0.5659 1677737 TimTec1_000055 CCCCC(=O)N1C(C)CC(Nc2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C12 compound treatment 0.189 -0.0574 -0.82 0.266 0.0233 0.39 -0.3046 -0.3348 3081441 TimTec1_000056 CCOC(=O)CCCc1ccc(/C=C/C(=O)O)s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C13 compound treatment 0.18 -0.0664 -0.95 0.261 0.0183 0.31 -0.455 -0.4556 3081442 TimTec1_000057 COC(=O)c1nsc(Cl)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C14 compound treatment 0.186 -0.0604 -0.86 0.231 -0.0117 -0.2 -0.7504 -0.8464 1003566 TimTec1_000058 S=C(Nc1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C15 compound treatment 0.208 -0.0384 -0.55 0.194 -0.0487 -0.82 -0.967 -0.9813 1060631 TimTec1_000059 COC(=O)C1=NNC(C1)(c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C16 compound treatment 0.21 -0.0364 -0.52 0.242 -7.19E-4 -0.01 -0.3771 -0.7233 3081443 TimTec1_000060 CN(C)/C=C(\C=[N+](C)C)/c1n[nH]cc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C17 compound treatment 0.219 -0.0274 -0.39 0.199 -0.0437 -0.73 -0.7964 -0.957 1149044 TimTec1_000061 Cc1cc(Cl)c(C(=O)N)c(C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C18 compound treatment 0.191 -0.0554 -0.79 0.187 -0.0557 -0.94 -1.222 -0.9966 1602135 TimTec1_000062 CN1CCc2c(C1)c3cc(C)ccc3n2CCc4ccncc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C19 compound treatment 0.204 -0.0424 -0.61 0.195 -0.0477 -0.8 -0.9956 -0.9906 3081444 TimTec1_000063 CCN1CCN(CC1)c2ccc(NC(=O)/C=C/c3ccccc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C20 compound treatment 0.207 -0.0394 -0.56 0.239 -0.00372 -0.06 -0.443 -0.7806 1241763 TimTec1_000064 Oc1ccc2occ(C(=O)c3cccs3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C21 compound treatment 0.224 -0.0224 -0.32 0.17 -0.0727 -1.22 -1.09 -0.8637 3081445 TimTec1_000065 Nc1nnnn1/N=C\2/C(=O)Nc3ccc(Br)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C22 compound treatment 0.239 -0.00744 -0.11 0.116 -0.127 -2.13 -1.5791 -0.7415 1336111 TimTec1_000066 COC(=O)CCc1[nH]c2ccccc2c1Sc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C23 mock treatment 0.264 0.0176 0.25 0.183 -0.0597 -1.0 -0.5311 -0.514 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 C24 mock treatment 0.255 0.00856 0.12 0.194 -0.0487 -0.82 -0.4916 -0.5946 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D01 compound treatment 0.204 -0.0424 -0.61 0.227 -0.0157 -0.26 -0.6158 -0.9304 1420975 TimTec1_000067 CSc1c(CC(=O)Nc2ccc(C)cc2)[nH]c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D02 compound treatment 0.196 -0.0504 -0.72 0.186 -0.0567 -0.95 -1.1833 -0.9906 3209598 TimTec1_000068 OC(=O)CCCC=C(c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D03 compound treatment 0.235 -0.0114 -0.16 0.201 -0.0417 -0.7 -0.6108 -0.8494 3209599 TimTec1_000069 Cc1[nH]c2ccccc2c1/C=N/CCc3ccncc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D04 compound treatment 0.196 -0.0504 -0.72 0.249 0.00628 0.11 -0.4356 -0.5974 3081446 TimTec1_000070 Brc1ccc(OC(=O)c2ccco2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D05 compound treatment 0.235 -0.0114 -0.16 0.229 -0.0137 -0.23 -0.2785 -0.986 3081447 TimTec1_000071 CCC(=O)n1c(SC)nc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D06 compound treatment 0.222 -0.0244 -0.35 0.278 0.0353 0.59 0.1716 0.2495 3209600 TimTec1_000072 Nc1nc(SCC(=O)NC2CCCCC2)c(C#N)cc1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D07 compound treatment 0.217 -0.0294 -0.42 0.255 0.0123 0.21 -0.152 -0.3242 3081448 TimTec1_000073 CCCc1ccc(s1)/C(=N/O)/C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D08 compound treatment 0.051 -0.195 -2.8 0.046 -0.197 -3.3 -4.3114 -0.9966 3209601 TimTec1_000074 CCOC(=O)CCSc1ccccn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D09 compound treatment 0.175 -0.0714 -1.02 0.186 -0.0567 -0.95 -1.3957 -0.9994 1380002 TimTec1_000075 CCOC(=O)c1c(CN(C)C)n(c2ccccc2)c3cc(Br)c(OC)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D10 compound treatment 0.257 0.0106 0.15 0.255 0.0123 0.21 0.2526 0.9883 3081452 TimTec1_000076 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(Cl)cc4Cl)C(=O)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D11 compound treatment 0.207 -0.0394 -0.56 0.207 -0.0357 -0.6 -0.8228 -0.9995 1674072 TimTec1_000077 Cn1c(CC(=O)O)c(c2ccccc12)S(=O)(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D12 compound treatment 0.186 -0.0604 -0.86 0.239 -0.00372 -0.06 -0.6554 -0.7562 1452087 TimTec1_000078 CCSc1nnc-2c(OC(Nc3ccccc32)C(=O)c4ccccc4)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D13 compound treatment 0.177 -0.0694 -0.99 0.184 -0.0587 -0.99 -1.3992 -1.0 1648799 TimTec1_000079 C(CN1CCN(CCSc2ccccc2)CC1)Sc3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D14 compound treatment 0.251 0.00456 0.07 0.206 -0.0367 -0.62 -0.3896 -0.6287 1276972 TimTec1_000080 Clc1ccccc1CN(Cc2cccnc2)C(=S)NC(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D15 compound treatment 0.227 -0.0194 -0.28 0.288 0.0453 0.76 0.3408 0.4211 1186617 TimTec1_000081 Cc1c([nH]c2ccc(OCc3ccccc3)cc12)C(=O)N4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D16 compound treatment 0.158 -0.0884 -1.26 0.19 -0.0527 -0.88 -1.5201 -0.9847 1357113 TimTec1_000082 CC1Oc2ccccc2OC1(O)c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D17 compound treatment 0.208 -0.0384 -0.55 0.255 0.0123 0.21 -0.243 -0.4139 3081458 TimTec1_000083 Brc1ccccc1NCn2nc(oc2=S)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D18 compound treatment 0.208 -0.0384 -0.55 0.257 0.0143 0.24 -0.2193 -0.3656 3209728 TimTec1_000084 Fc1ccccc1OC(=O)N2c3ccccc3Sc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D19 compound treatment 0.258 0.0116 0.17 0.233 -0.00972 -0.16 0.0016 0.0069 1270584 TimTec1_000085 Cc1ccc(cc1)S(=O)(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D20 compound treatment 0.248 0.00156 0.02 0.275 0.0323 0.54 0.3989 0.7356 3081461 TimTec1_000086 FC(F)(F)c1cccc(c1)c2ccc(/C=N\C3CCS(=O)(=O)C3)o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D21 compound treatment 0.221 -0.0254 -0.36 0.269 0.0263 0.44 0.0546 0.0955 1450123 TimTec1_000087 CCOC(=O)c1c(C)n(c2cccc(C)c2)c3ccc(O)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D22 compound treatment 0.273 0.0266 0.38 0.264 0.0213 0.36 0.5212 0.9995 3209729 TimTec1_000088 Cc1cccc(c1)C2Sc3ccccc3N=C4C2C(=O)c5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D23 mock treatment 0.221 -0.0254 -0.36 0.241 -0.00172 -0.03 -0.2777 -0.7608 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 D24 mock treatment 0.195 -0.0514 -0.74 0.247 0.00428 0.07 -0.4694 -0.635 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E01 compound treatment 0.209 -0.0374 -0.54 0.239 -0.00372 -0.06 -0.4228 -0.7842 3209730 TimTec1_000089 CSc1ccccc1NC(=O)c2cc3NC4C(CCc5ccccc45)C(n3n2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E02 compound treatment 0.233 -0.0134 -0.19 0.231 -0.0117 -0.2 -0.275 -0.9999 3081503 TimTec1_000090 Nc1c(C#N)c(cc(c1C#N)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E03 compound treatment 0.219 -0.0274 -0.39 0.267 0.0243 0.41 0.0107 0.0188 3081507 TimTec1_000091 Cc1c(Br)c(nn1CC(=O)N2CCOCC2)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E04 compound treatment 0.225 -0.0214 -0.31 0.221 -0.0217 -0.36 -0.4746 -0.9963 1912602 TimTec1_000092 Brc1cccc(c1)C2C3CCCCC3=C(C#N)C(=O)C2(C#N)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E05 compound treatment 0.196 -0.0504 -0.72 0.181 -0.0617 -1.04 -1.2426 -0.9844 3209731 TimTec1_000093 C[N+](C)(C)CC1CCCC1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E06 compound treatment 0.183 -0.0634 -0.91 0.178 -0.0647 -1.09 -1.4097 -0.996 3081510 TimTec1_000094 [N-]=[N+]=NCc1noc(n1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E07 compound treatment 0.233 -0.0134 -0.19 0.243 2.81E-4 0.0 -0.1326 -0.6895 1182023 TimTec1_000095 CCCN(C#N)c1nc(NC(C)C)nc(NC(C)C)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E08 compound treatment 0.28 0.0336 0.48 0.264 0.0213 0.36 0.592 0.9894 3081512 TimTec1_000096 O=C(NCC[n+]1ccc2ccccc2c1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E09 compound treatment 0.238 -0.00844 -0.12 0.184 -0.0587 -0.99 -0.7822 -0.7878 1029436 TimTec1_000097 OC(=O)CCC(=O)Oc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E10 compound treatment 0.214 -0.0324 -0.46 0.17 -0.0727 -1.22 -1.1911 -0.9122 3209732 TimTec1_000098 Nc1ccc(OCC(O)C[n+]2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E11 compound treatment 0.199 -0.0474 -0.68 0.206 -0.0367 -0.62 -0.9156 -0.9988 3081515 TimTec1_000099 O=C(Nc1cccc(NC(=O)/C=C/c2ccco2)n1)/C=C/c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E12 compound treatment 0.235 -0.0114 -0.16 0.225 -0.0177 -0.3 -0.326 -0.9604 1009007 TimTec1_000100 CCCC(=O)NCc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E13 compound treatment 0.205 -0.0414 -0.59 0.211 -0.0317 -0.53 -0.7955 -0.9986 1705451 TimTec1_000101 CC1C2COCC2CC(C1O)N(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E14 compound treatment 0.222 -0.0244 -0.35 0.245 0.00228 0.04 -0.2201 -0.6259 1074947 TimTec1_000102 Cc1ccc[n+](Cc2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E15 compound treatment 0.236 -0.0104 -0.15 0.224 -0.0187 -0.31 -0.3277 -0.9422 1394494 TimTec1_000103 Nc1ccc(c2nc3cc(Cl)ccc3o2)c(O)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E16 compound treatment 0.216 -0.0304 -0.44 0.223 -0.0197 -0.33 -0.5419 -0.9908 3209733 TimTec1_000104 CN(C)/C=C(\C=[N+](C)C)/c1cc([nH]n1)\C(=C/N(C)C)\C=[N+](C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E17 compound treatment 0.173 -0.0734 -1.05 0.187 -0.0557 -0.94 -1.404 -0.9983 3081522 TimTec1_000105 Oc1ccc(Cl)cc1/N=C/c2ccc(o2)c3ccc(Br)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E18 compound treatment 0.23 -0.0164 -0.24 0.234 -0.00872 -0.15 -0.2697 -0.974 1633318 TimTec1_000106 Oc1ccc2occ(C(=O)c3ccc(Oc4ccccc4)cc3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E19 compound treatment 0.213 -0.0334 -0.48 0.185 -0.0577 -0.97 -1.0232 -0.9471 1221609 TimTec1_000107 CCOC(=O)C1(COC(=O)C1)c2csc(N)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E20 compound treatment 0.211 -0.0354 -0.51 0.28 0.0373 0.63 0.084 0.1044 1365512 TimTec1_000108 CSc1c(CC(=O)NCCc2ccccc2)n(C)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E21 compound treatment 0.247 5.62E-4 0.01 0.246 0.00328 0.06 0.0446 0.8019 3081562 TimTec1_000109 Cc1c(/C=N/c2cccc3nsnc23)c(O)n4c5ccccc5nc4c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E22 compound treatment 0.042 -0.204 -2.92 0.041 -0.202 -3.39 -4.4617 -0.9973 1408177 TimTec1_000110 O=C(CCN1CCCCC1)c2cc3ccccc3o2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E23 mock treatment 0.24 -0.00644 -0.09 0.229 -0.0137 -0.23 -0.2279 -0.9191 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 E24 mock treatment 0.218 -0.0284 -0.41 0.211 -0.0317 -0.53 -0.6641 -0.9912 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F01 compound treatment 0.237 -0.00944 -0.13 0.235 -0.00772 -0.13 -0.1871 -0.9998 1212077 TimTec1_000111 CCOC(=O)c1cc2ccccc2nc1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F02 compound treatment 0.219 -0.0274 -0.39 0.241 -0.00172 -0.03 -0.2979 -0.757 3209734 TimTec1_000112 C=CCNC(=O)CC1CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F03 compound treatment 0.195 -0.0514 -0.74 0.196 -0.0467 -0.78 -1.0747 -0.9995 3209735 TimTec1_000113 COc1ccc(O)c(c1)c2c[nH]c(=S)nc2c3cc(OC)ccc3OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F04 compound treatment 0.181 -0.0654 -0.94 0.189 -0.0537 -0.9 -1.2994 -0.9998 1743325 TimTec1_000114 COc1ccc2nc3-c4cccc5cccc(-c3nc2c1)c45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F05 compound treatment 0.219 -0.0274 -0.39 0.201 -0.0417 -0.7 -0.7726 -0.9626 2104259 TimTec1_000115 Brc1cccc(c1)c2n[nH]c(=O)[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F06 compound treatment 0.208 -0.0384 -0.55 0.23 -0.0127 -0.21 -0.5397 -0.9151 1644388 TimTec1_000116 O=S(=O)(CCc1ccncc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F07 compound treatment 0.218 -0.0284 -0.41 0.269 0.0263 0.44 0.0243 0.0405 1066566 TimTec1_000117 Cc1ccc(cc1)S(=O)(=O)N2CCC(=O)c3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F08 compound treatment 0.23 -0.0164 -0.24 0.226 -0.0167 -0.28 -0.3647 -0.9961 1595822 TimTec1_000118 Nc1ccc(cc1)C(=O)NCC2CCCN3CCCCC23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F09 compound treatment 0.208 -0.0384 -0.55 0.223 -0.0197 -0.33 -0.6228 -0.9705 3209736 TimTec1_000119 CN(C)Cc1c(C#N)c2ccccc2n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F10 compound treatment 0.2 -0.0464 -0.66 0.204 -0.0387 -0.65 -0.9292 -0.9999 3081571 TimTec1_000120 Cc1c(O)n(nc1/C=N/n2cnnc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F11 compound treatment 0.192 -0.0544 -0.78 0.288 0.0453 0.76 -0.0132 -0.0121 3209737 TimTec1_000121 Oc1ccc(cc1)n2cccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F12 compound treatment 0.246 -4.38E-4 -0.01 0.264 0.0213 0.36 0.2481 0.6946 1378112 TimTec1_000122 CC(C)(C)C(=O)c1sc2nc3CCCc3c(c4cccs4)c2c1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F13 compound treatment 0.257 0.0106 0.15 0.276 0.0333 0.56 0.5018 0.8672 1389415 TimTec1_000123 Clc1cccc(OCCN2CCOCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F14 compound treatment 0.3 0.0536 0.77 0.211 -0.0317 -0.53 0.1653 0.1772 3209738 TimTec1_000124 COc1ccc(C/N=C/C2C(=O)N(N=C2C(F)(F)F)c3nc4ccccc4s3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F15 compound treatment 0.241 -0.00544 -0.08 0.298 0.0553 0.93 0.6011 0.6456 1562364 TimTec1_000125 CN1CCN(CCOc2ccccc2)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F16 compound treatment 0.236 -0.0104 -0.15 0.287 0.0443 0.74 0.42 0.554 1380422 TimTec1_000126 Brc1ccccc1OCc2nc3ccccc3[nH]2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F17 compound treatment 0.246 -4.38E-4 -0.01 0.251 0.00828 0.14 0.0939 0.6746 1337811 TimTec1_000127 COc1ccc(NC(=O)c2ccc3nc(C)c(C)nc3c2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F18 compound treatment 0.209 -0.0374 -0.54 0.26 0.0173 0.29 -0.1736 -0.285 3209739 TimTec1_000128 O=C(/C=C/C(=O)c1ccccc1)N2c3ccccc3Sc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F19 compound treatment 0.243 -0.00344 -0.05 0.239 -0.00372 -0.06 -0.0789 -0.993 1683844 TimTec1_000129 CC1(C)CC(C)(c2ccccc2)c3cc(SC#N)ccc3N1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F20 compound treatment 0.23 -0.0164 -0.24 0.285 0.0423 0.71 0.3355 0.4488 1442200 TimTec1_000130 CC1CCN(CC(O)COc2c(F)cc(Br)cc2F)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F21 compound treatment 0.29 0.0436 0.62 0.247 0.00428 0.07 0.4914 0.7835 1404864 TimTec1_000131 OCCN(CCO)Cc1c(O)ccc2occ(C(=O)c3cccs3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F22 compound treatment 0.294 0.0476 0.68 0.241 -0.00172 -0.03 0.4607 0.6765 1413355 TimTec1_000132 CSC1=NC2(CCCCC2)NC3=C1CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F23 mock treatment 0.282 0.0356 0.51 0.28 0.0373 0.63 0.8021 0.9947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 F24 mock treatment 0.242 -0.00444 -0.06 0.198 -0.0447 -0.75 -0.5756 -0.7642 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G01 compound treatment 0.247 5.62E-4 0.01 0.256 0.0133 0.22 0.1633 0.7322 1746897 TimTec1_000133 CC1Cc2ccccc2N1C(=O)c3cccc(n3)C(=O)N4C(C)Cc5ccccc45 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G02 compound treatment 0.239 -0.00744 -0.11 0.279 0.0363 0.61 0.3554 0.5749 1210571 TimTec1_000134 CCOC(=O)C1(C#N)C(C=C(C(=C1N)C#N)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G03 compound treatment 0.234 -0.0124 -0.18 0.247 0.00428 0.07 -0.075 -0.3908 1738871 TimTec1_000135 O=C(C1CC1(c2ccccc2)c3ccccc3)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G04 compound treatment 0.2 -0.0464 -0.66 0.235 -0.00772 -0.13 -0.5613 -0.8294 1495985 TimTec1_000136 CC(C)Cc1cc(c(C#N)c(N)n1)c2cccc(Br)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G05 compound treatment 0.215 -0.0314 -0.45 0.263 0.0203 0.34 -0.0773 -0.137 1728047 TimTec1_000137 CC(C)(C)c1cc(CCC(=O)NCCN)cc(c1O)C(C)(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G06 compound treatment 0.213 -0.0334 -0.48 0.226 -0.0167 -0.28 -0.5366 -0.9677 1006115 TimTec1_000138 CCN(CC)C1CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G07 compound treatment 0.268 0.0216 0.31 0.286 0.0433 0.73 0.7318 0.9272 1442213 TimTec1_000139 CN(C)c1nc(Cl)nc(n1)N(CN2C(=O)c3ccccc3C2=O)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G08 compound treatment 0.263 0.0166 0.24 0.236 -0.00672 -0.11 0.0878 0.3346 1391498 TimTec1_000140 Cc1nc2n(C)c(=O)n(C)c(=O)c2cc1C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G09 compound treatment 0.188 -0.0584 -0.84 0.215 -0.0277 -0.47 -0.92 -0.9617 1225682 TimTec1_000141 CC(C)Nc1nc(NC(C)C)nc(n1)N(C)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G10 compound treatment 0.065 -0.181 -2.6 0.056 -0.187 -3.13 -4.0511 -0.9956 1485808 TimTec1_000142 Cc1cccc(C[N+](C)(C)CCC(=O)c2ccccc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G11 compound treatment 0.249 0.00256 0.04 0.278 0.0353 0.59 0.4446 0.7494 1186157 TimTec1_000143 CC12CCCCC2=NC(N1O)c3ccccc3O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G12 compound treatment 0.216 -0.0304 -0.44 0.268 0.0253 0.42 -0.0078 -0.0128 1025931 TimTec1_000144 Cc1ccc(cc1)S(=O)(=O)NCc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G13 compound treatment 0.053 -0.193 -2.77 0.046 -0.197 -3.3 -4.2911 -0.9961 1323961 TimTec1_000145 S=C(CC(=S)N1CCOCC1)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G14 compound treatment 0.254 0.00756 0.11 0.244 0.00128 0.02 0.0917 0.8314 3209861 TimTec1_000146 CC(=O)NC1CCCCc2sccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G15 compound treatment 0.243 -0.00344 -0.05 0.295 0.0523 0.88 0.5857 0.6664 1288570 TimTec1_000147 CCCC(CCC)c1nc2ccncc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G16 compound treatment 0.258 0.0116 0.17 0.246 0.00328 0.06 0.1559 0.8943 3209862 TimTec1_000148 OC1=C(C2C3C(CCCC3=O)Oc4ccccc24)C(=O)CCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G17 compound treatment 0.284 0.0376 0.54 0.249 0.00628 0.11 0.4545 0.83 3081632 TimTec1_000149 OC(=O)CCC/N=C(\c1ccc(Cl)cc1)/c2cc(F)ccc2O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G18 compound treatment 0.187 -0.0594 -0.85 0.198 -0.0447 -0.75 -1.1319 -0.9981 1713094 TimTec1_000150 CN(C)Cc1c(O)ccc2occ(C(=O)c3cccc(Br)c3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G19 compound treatment 0.227 -0.0194 -0.28 0.255 0.0123 0.21 -0.0508 -0.1469 3081667 TimTec1_000151 CCCC1CC(C)(OC1=O)C(=O)C[n+]2cccc(c2)C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G20 compound treatment 0.25 0.00356 0.05 0.263 0.0203 0.34 0.2767 0.804 1405391 TimTec1_000152 COc1ccc(OC)c(c1)C(=O)c2coc3ccc(O)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G21 compound treatment 0.249 0.00256 0.04 0.235 -0.00772 -0.13 -0.0657 -0.4879 3081670 TimTec1_000153 CC(C)C1(CN2CC/3CN(C1)CC2)\C3=N/N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G22 compound treatment 0.196 -0.0504 -0.72 0.275 0.0323 0.54 -0.127 -0.1408 1185154 TimTec1_000154 CCOC(=O)Cn1c(C)c(Sc2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G23 mock treatment 0.198 -0.0484 -0.69 0.219 -0.0237 -0.4 -0.7714 -0.9654 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 G24 mock treatment 0.22 -0.0264 -0.38 0.19 -0.0527 -0.88 -0.8931 -0.9281 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H01 compound treatment 0.222 -0.0244 -0.35 0.207 -0.0357 -0.6 -0.6711 -0.967 1114526 TimTec1_000155 NC(=O)c1ccccc1C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H02 compound treatment 0.22 -0.0264 -0.38 0.257 0.0143 0.24 -0.0979 -0.2187 3209863 TimTec1_000156 CC(C)c1ccc(cc1)C(C)(C)CO 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H03 compound treatment 0.224 -0.0224 -0.32 0.239 -0.00372 -0.06 -0.2711 -0.8291 1440514 TimTec1_000157 COc1ccccc1OCCN2CCN(CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H04 compound treatment 0.244 -0.00244 -0.03 0.303 0.0603 1.01 0.6908 0.6823 3081674 TimTec1_000158 Cc1c(/C=C/c2ccc(Cl)cc2Cl)c(=O)n(c3ccccc3)n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H05 compound treatment 0.24 -0.00644 -0.09 0.294 0.0513 0.86 0.5435 0.6279 3209864 TimTec1_000159 COc1ccc(Br)c2OCCOc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H06 compound treatment 0.179 -0.0674 -0.96 0.172 -0.0707 -1.19 -1.5214 -0.9947 3209865 TimTec1_000160 COc1ccc(NC(=O)CC(=O)CSc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H07 compound treatment 0.214 -0.0324 -0.46 0.264 0.0213 0.36 -0.0755 -0.129 1282382 TimTec1_000161 CN1CCN(Cc2c(C#N)c3ccccc3n2C)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H08 compound treatment 0.262 0.0156 0.22 0.253 0.0103 0.17 0.2794 0.9921 1156260 TimTec1_000162 O=C(CSc1nc2ccccc2o1)Nc3ccccn3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H09 compound treatment 0.258 0.0116 0.17 0.217 -0.0257 -0.43 -0.1883 -0.4073 1296268 TimTec1_000163 Cn1c(CN2CCOCC2)c(C#N)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H10 compound treatment 0.227 -0.0194 -0.28 0.244 0.00128 0.02 -0.1814 -0.6505 1566355 TimTec1_000164 C1CCC(CC1)Nc2c(nnn2C3CCCCC3)c4ccn[nH]4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H11 compound treatment 0.268 0.0216 0.31 0.233 -0.00972 -0.16 0.1027 0.2945 3081679 TimTec1_000165 CNC(=O)CCc1cc2ccccc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H12 compound treatment 0.272 0.0256 0.37 0.247 0.00428 0.07 0.3094 0.8302 1429944 TimTec1_000166 NC(=S)c1cnc2ccccn2c1=N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H13 compound treatment 0.294 0.0476 0.68 0.215 -0.0277 -0.47 0.1521 0.1845 1210033 TimTec1_000167 O=C(CCN1CCN(CC1)c2ccccc2)Nc3nccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H14 compound treatment 0.255 0.00856 0.12 0.261 0.0183 0.31 0.3036 0.9189 3209866 TimTec1_000168 FC(F)(F)c1[nH]n(c2nc3ccccc3s2)c(=O)c1/C=N/CCN4CCOCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H15 compound treatment 0.267 0.0206 0.29 0.316 0.0733 1.23 1.0777 0.8522 3081684 TimTec1_000169 COc1ccc(/C=N/c2oc(C)c(C)c2C#N)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H16 compound treatment 0.261 0.0146 0.21 0.249 0.00628 0.11 0.2218 0.9502 3209867 TimTec1_000170 C[n+]1c(COc2ccccc2O)sc3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H17 compound treatment 0.281 0.0346 0.49 0.275 0.0323 0.54 0.7327 0.999 1912978 TimTec1_000171 CC(=O)N1c2ccccc2C(C)(CC1(C)C)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H18 compound treatment 0.264 0.0176 0.25 0.24 -0.00272 -0.05 0.1454 0.5693 3081687 TimTec1_000172 Cn1ccnc1C(=O)Oc2ccccc2F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H19 compound treatment 0.217 -0.0294 -0.42 0.216 -0.0267 -0.45 -0.6148 -0.9995 1280653 TimTec1_000173 CC1=CC(C)(C)N(c2ccccc12)S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H20 compound treatment 0.251 0.00456 0.07 0.265 0.0223 0.37 0.3106 0.8181 3209868 TimTec1_000174 O=c1[nH]c2ccc(/N=C/c3ccc4OCOc4c3)cc2[nH]1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H21 compound treatment 0.28 0.0336 0.48 0.265 0.0223 0.37 0.6039 0.9924 3081729 TimTec1_000175 Nc1no[n+]([O-])c1c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H22 compound treatment 0.244 -0.00244 -0.03 0.291 0.0483 0.81 0.5484 0.6761 3081731 TimTec1_000176 CCOc1ccc2S/C(=C/NC(C)CC)/C(=O)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H23 mock treatment 0.229 -0.0174 -0.25 0.218 -0.0247 -0.41 -0.4697 -0.9704 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 H24 mock treatment 0.215 -0.0314 -0.45 0.249 0.00628 0.11 -0.2434 -0.527 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I01 compound treatment 0.197 -0.0494 -0.71 0.27 0.0273 0.46 -0.1762 -0.2092 1160113 TimTec1_000177 Cc1ccccc1OCC(=O)Nc2ccc3nn(nc3c2)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I02 compound treatment 0.255 0.00856 0.12 0.301 0.0583 0.98 0.7783 0.7895 1912584 TimTec1_000178 Nc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I03 compound treatment 0.241 -0.00544 -0.08 0.211 -0.0317 -0.53 -0.4314 -0.8019 3081734 TimTec1_000179 COC(=O)CCC(=O)Nc1nccs1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I04 compound treatment 0.28 0.0336 0.48 0.282 0.0393 0.66 0.8057 0.9879 1175548 TimTec1_000180 CC(=O)Nc1nc(cc(c1C#N)c2ccccc2)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I05 compound treatment 0.26 0.0136 0.19 0.248 0.00528 0.09 0.1999 0.937 1060191 TimTec1_000181 S=C1N(CN2CCCCC2)CCN1CN3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I06 compound treatment 0.267 0.0206 0.29 0.231 -0.0117 -0.2 0.0689 0.1947 3209869 TimTec1_000182 CC[N+](C)(CC)Cc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I07 compound treatment 0.262 0.0156 0.22 0.274 0.0313 0.53 0.5287 0.927 3209870 TimTec1_000183 Cc1cc(NN)nc(SCC(=O)NN)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I08 compound treatment 0.257 0.0106 0.15 0.242 -7.19E-4 -0.01 0.0983 0.6486 1289525 TimTec1_000184 C[N+]1(CC(O)C[N+]2(C)CCCCC2)CCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I09 compound treatment 0.252 0.00556 0.08 0.226 -0.0167 -0.28 -0.1422 -0.4874 1505713 TimTec1_000185 C1=C(N=C2C=Cc3nonc3C12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I10 compound treatment 0.235 -0.0114 -0.16 0.254 0.0113 0.19 0.0182 0.0728 1080215 TimTec1_000186 OP(=O)(Nc1ccccc1)Nc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I11 compound treatment 0.238 -0.00844 -0.12 0.253 0.0103 0.17 0.0367 0.1742 3209871 TimTec1_000187 Cc1c(Br)c(nn1CC(=O)N)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I12 compound treatment 0.288 0.0416 0.59 0.27 0.0273 0.46 0.7441 0.9917 1668354 TimTec1_000188 O=C(N1CCCCC1)c2ccccc2C(=O)N3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I13 compound treatment 0.284 0.0376 0.54 0.23 -0.0127 -0.21 0.229 0.396 1230919 TimTec1_000189 CN(C)CCNc1nc(no1)c2noc(NCCN(C)C)n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I14 compound treatment 0.259 0.0126 0.18 0.267 0.0243 0.41 0.4152 0.9323 1641088 TimTec1_000190 C[N+]1(CC(O)CN2CCCC2=O)CCCCCC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I15 compound treatment 0.281 0.0346 0.49 0.298 0.0553 0.93 1.0057 0.9566 1479834 TimTec1_000191 CC1(C)CC(CC(C)(C)N1)NC(=O)N2c3ccccc3CCc4ccccc24 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I16 compound treatment 0.212 -0.0344 -0.49 0.279 0.0363 0.61 0.0823 0.1051 3209872 TimTec1_000192 CCOC(=O)C1(C#N)C(C#N)(C(=O)OCC)C1(C#N)C(=O)OCC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I17 compound treatment 0.214 -0.0324 -0.46 0.225 -0.0177 -0.3 -0.5384 -0.9769 1350657 TimTec1_000193 COc1ccc2NC(C)(C)c3ssc(=S)c3-c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I18 compound treatment 0.262 0.0156 0.22 0.282 0.0393 0.66 0.6236 0.8961 1439817 TimTec1_000194 CC(=O)Oc1ccc2occ(C(=O)c3cc4ccccc4o3)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I19 compound treatment 0.279 0.0326 0.47 0.266 0.0233 0.39 0.6056 0.9962 1619809 TimTec1_000195 Nc1nc(cc(c1C#N)c2ccccc2Cl)C3CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I20 compound treatment 0.051 -0.195 -2.8 0.044 -0.199 -3.34 -4.3351 -0.9961 1402303 TimTec1_000196 CN(C)CCC(=O)c1coc2ccc(OC(=O)C)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I21 compound treatment 0.23 -0.0164 -0.24 0.192 -0.0507 -0.85 -0.7682 -0.8698 3209873 TimTec1_000197 C/C(=N\n1nnnc1Nc2ccccc2)/c3ccccc3Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I22 compound treatment 0.22 -0.0264 -0.38 0.247 0.00428 0.07 -0.2166 -0.5627 1447918 TimTec1_000198 COC(=O)CCC(=O)c1cc2cc(Br)ccc2o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I23 mock treatment 0.238 -0.00844 -0.12 0.297 0.0543 0.91 0.5589 0.6081 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 I24 mock treatment 0.208 -0.0384 -0.55 0.236 -0.00672 -0.11 -0.4685 -0.8348 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J01 compound treatment 0.216 -0.0304 -0.44 0.273 0.0303 0.51 0.0515 0.077 1078582 TimTec1_000199 NC(=O)c1ccc2ccccc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J02 compound treatment 0.229 -0.0174 -0.25 0.3 0.0573 0.96 0.5035 0.5069 1032512 TimTec1_000200 O=C1N(CNc2ccccc2)C(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J03 compound treatment 0.227 -0.0194 -0.28 0.238 -0.00472 -0.08 -0.2526 -0.8738 1725358 TimTec1_000201 Cc1ccc(cc1)S(=O)(=O)CCN2CCN(CC2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J04 compound treatment 0.241 -0.00544 -0.08 0.212 -0.0307 -0.52 -0.4196 -0.8047 1122981 TimTec1_000202 O=C1NC(=O)c2cc(ccc12)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J05 compound treatment 0.266 0.0196 0.28 0.263 0.0203 0.34 0.4386 0.9953 1020688 TimTec1_000203 Cc1ccc(NC(=O)CC(=O)Nc2ccc(C)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J06 compound treatment 0.298 0.0516 0.74 0.224 -0.0187 -0.31 0.2994 0.3734 1386865 TimTec1_000204 COC(=O)c1ccc(NC(=O)COc2cccc3ccccc23)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J07 compound treatment 0.274 0.0276 0.39 0.237 -0.00572 -0.1 0.2109 0.5198 1498066 TimTec1_000205 CC(=O)Nc1c(oc2ccccc12)C(=O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J08 compound treatment 0.266 0.0196 0.28 0.268 0.0253 0.42 0.4979 0.9796 1326858 TimTec1_000206 CN1CCc2c(C1)c(nc3[nH]nc(N)c23)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J09 compound treatment 0.259 0.0126 0.18 0.272 0.0293 0.49 0.4746 0.9069 1734489 TimTec1_000207 Cn1c(CSCc2ccccc2)c(C#N)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J10 compound treatment 0.253 0.00656 0.09 0.264 0.0213 0.36 0.3189 0.8636 3209874 TimTec1_000208 O/N=C\1/C2CN3CC1(Cc4ccccc4)CN(C2)CC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J11 compound treatment 0.25 0.00356 0.05 0.29 0.0473 0.79 0.5972 0.751 3081797 TimTec1_000209 S(c1ccccn1)c2ncnc3c4ccccc4oc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J12 compound treatment 0.256 0.00956 0.14 0.252 0.00928 0.16 0.2069 0.9979 3209875 TimTec1_000210 CCOC(=O)[C@@]1(C#N)[C@H]([C@@H](N2C=C(C=C[C@H]21)C(=O)N)C(=O)N)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J13 compound treatment 0.308 0.0616 0.88 0.311 0.0683 1.15 1.433 0.9915 3081799 TimTec1_000211 C(Sc1ncnc2c3ccccc3oc12)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J14 compound treatment 0.279 0.0326 0.47 0.278 0.0353 0.59 0.7481 0.9929 3081800 TimTec1_000212 FC(F)(F)c1[nH]n(c2nc3ccccc3s2)c(=O)c1/C=N/Cc4cccnc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J15 compound treatment 0.255 0.00856 0.12 0.264 0.0213 0.36 0.3392 0.8982 1498770 TimTec1_000213 COc1cc(OC)cc(c1)C(=O)N2CCc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J16 compound treatment 0.253 0.00656 0.09 0.273 0.0303 0.51 0.4258 0.8238 1358111 TimTec1_000214 Oc1ccccc1OCC(=O)N2CCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J17 compound treatment 0.273 0.0266 0.38 0.302 0.0593 0.99 0.9722 0.9128 1091978 TimTec1_000215 CCOC(=O)CN=C(c1ccccc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J18 compound treatment 0.282 0.0356 0.51 0.29 0.0473 0.79 0.9208 0.9769 1917358 TimTec1_000216 CN1CCN(CC(O)COCCC2(CC3CC4CC(C3)C2)C4)CC1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J19 compound treatment 0.285 0.0386 0.55 0.277 0.0343 0.58 0.7969 0.9998 1066363 TimTec1_000217 COc1ccc2NC(C)(C)C=C(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J20 compound treatment 0.286 0.0396 0.57 0.281 0.0383 0.64 0.8545 0.998 1921867 TimTec1_000218 On1c(nc-2c1CCc3c2no[n+]3[O-])c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J21 compound treatment 0.056 -0.19 -2.72 0.082 -0.161 -2.7 -3.8336 -1.0 3081805 TimTec1_000219 Nc1c(no[n+]1[O-])C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J22 compound treatment 0.273 0.0266 0.38 0.239 -0.00372 -0.06 0.2245 0.5831 1879059 TimTec1_000220 CNC(=O)N(Cc1cccnc1)Cc2ccccc2Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J23 mock treatment 0.279 0.0326 0.47 0.226 -0.0167 -0.28 0.1309 0.2408 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 J24 mock treatment 0.245 -0.00144 -0.02 0.197 -0.0457 -0.77 -0.5571 -0.7258 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K01 compound treatment 0.237 -0.00944 -0.13 0.306 0.0633 1.06 0.6556 0.6123 1259801 TimTec1_000221 CS(=O)(=O)c1ccc2nc(NC(=O)C3CCCO3)sc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K02 compound treatment 0.265 0.0186 0.27 0.248 0.00528 0.09 0.2504 0.8946 1151146 TimTec1_000222 Nc1c(C#N)c(c2ccccc2)c3CCCCc3c1C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K03 compound treatment 0.236 -0.0104 -0.15 0.268 0.0253 0.42 0.1945 0.4323 1392387 TimTec1_000223 Brc1ccc(o1)C(=O)Nc2ccc3OCOc3c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K04 compound treatment 0.257 0.0106 0.15 0.261 0.0183 0.31 0.3238 0.9467 1275980 TimTec1_000224 Clc1ccc(OCC(=O)NCC=C)c(Cl)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K05 compound treatment 0.265 0.0186 0.27 0.253 0.0103 0.17 0.3098 0.9782 1285366 TimTec1_000225 Cc1cccc(CN2CCN(Cc3cccc(C)c3O)CC2)c1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K06 compound treatment 0.266 0.0196 0.28 0.262 0.0193 0.32 0.4267 0.9974 3081809 TimTec1_000226 Cc1cc(C)nc(SCC(=O)NN)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K07 compound treatment 0.24 -0.00644 -0.09 0.28 0.0373 0.63 0.3773 0.5966 1584109 TimTec1_000227 NNC(=O)C1CC2CC1CC2C(=O)NN 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K08 compound treatment 0.276 0.0296 0.42 0.287 0.0443 0.74 0.8245 0.9643 1914424 TimTec1_000228 C(=N/C(\N=C\c1ccccc1)c2ccccc2)\c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K09 compound treatment 0.283 0.0366 0.52 0.282 0.0393 0.66 0.836 0.9934 3081861 TimTec1_000229 COC(=O)c1ccc(NC(=S)NC(=O)N2CCOCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K10 compound treatment 0.261 0.0146 0.21 0.276 0.0333 0.56 0.5423 0.9096 3209999 TimTec1_000230 CC(=O)OC1COC(NC(=S)Oc2ccccc2)C(OC(=O)C)C1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K11 compound treatment 0.263 0.0166 0.24 0.299 0.0563 0.94 0.8355 0.8579 3081863 TimTec1_000231 CCOC(=O)Cn1nc(cc1C)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K12 compound treatment 0.231 -0.0154 -0.22 0.248 0.00528 0.09 -0.0935 -0.3928 3210000 TimTec1_000232 COc1ccc(/C=C/C(=O)OC2CCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K13 compound treatment 0.042 -0.204 -2.92 0.044 -0.199 -3.34 -4.4261 -0.9979 3081865 TimTec1_000233 c1ccc(cc1)c2cnc3nonc3n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K14 compound treatment 0.295 0.0486 0.69 0.264 0.0213 0.36 0.7437 0.9522 1474168 TimTec1_000234 COc1ccc(CCN(C)C(=S)NN)cc1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K15 compound treatment 0.234 -0.0124 -0.18 0.294 0.0513 0.86 0.4828 0.5493 1445690 TimTec1_000235 OC(=O)c1cc2cccc(c2cc1O)S(=O)(=O)N3CCCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K16 compound treatment 0.225 -0.0214 -0.31 0.271 0.0283 0.47 0.1188 0.2103 1033126 TimTec1_000236 Cc1ccc(cc1)S(=O)(=O)Nc2cccc3ccccc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K17 compound treatment 0.258 0.0116 0.17 0.27 0.0273 0.46 0.4407 0.9053 1183681 TimTec1_000237 COc1cc(NC(=O)Cc2ccc(F)cc2)cc(c1)S(=O)(=O)c3ccc(Cl)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K18 compound treatment 0.229 -0.0174 -0.25 0.253 0.0103 0.17 -0.0543 -0.1792 1604299 TimTec1_000238 COc1cc2c(NC(=O)C)c(CN(C)C)oc2c(Cl)c1Cl 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K19 compound treatment 0.231 -0.0154 -0.22 0.238 -0.00472 -0.08 -0.2121 -0.9043 3210001 TimTec1_000239 NS(=O)(=O)c1ccc(NC=C2C(=O)c3ccccc3C2=O)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K20 compound treatment 0.092 -0.154 -2.21 0.099 -0.144 -2.41 -3.2677 -0.999 3081870 TimTec1_000240 CCOC(=O)CSc1c([nH]c2ccccc12)c3cccs3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K21 compound treatment 0.248 0.00156 0.02 0.247 0.00428 0.07 0.0666 0.8852 3210002 TimTec1_000241 S=c1n(CN(Cc2ccccc2)Cc3ccccc3)nnn1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K22 compound treatment 0.044 -0.202 -2.9 0.043 -0.2 -3.35 -4.4178 -0.9973 1023688 TimTec1_000242 CN(C)CCC(=O)c1ccco1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K23 mock treatment 0.194 -0.0524 -0.75 0.215 -0.0277 -0.47 -0.8593 -0.9736 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 K24 mock treatment 0.278 0.0316 0.45 0.212 -0.0307 -0.52 -0.0453 -0.0662 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L01 compound treatment 0.249 0.00256 0.04 0.255 0.0123 0.21 0.1717 0.82 1264988 TimTec1_000243 COc1cc(N)c(Cl)cc1C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L02 compound treatment 0.227 -0.0194 -0.28 0.256 0.0133 0.22 -0.039 -0.1094 1706058 TimTec1_000244 CC(=O)N(CN1C(=O)c2ccccc2C1=O)c3ccccc3C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L03 compound treatment 0.203 -0.0434 -0.62 0.244 0.00128 0.02 -0.4241 -0.6822 1357677 TimTec1_000245 CNC(=O)c1cnc2cc(Cl)ccc2c1OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L04 compound treatment 0.218 -0.0284 -0.41 0.269 0.0263 0.44 0.0243 0.0405 1569209 TimTec1_000246 O=S(=O)(NC1c2ccccc2Oc3ccccc13)c4ccc5ccccc5c4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L05 compound treatment 0.196 -0.0504 -0.72 0.233 -0.00972 -0.16 -0.6255 -0.8456 1015215 TimTec1_000247 COc1ccc(NC(=O)CC(=O)Nc2ccc(OC)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L06 compound treatment 0.196 -0.0504 -0.72 0.274 0.0313 0.53 -0.1389 -0.1557 1490465 TimTec1_000248 COc1ccc(SCC(=O)Nc2ccccn2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L07 compound treatment 0.261 0.0146 0.21 0.29 0.0473 0.79 0.7084 0.8635 1204062 TimTec1_000249 CSc1c(CC(=O)NN)n(C)c2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L08 compound treatment 0.263 0.0166 0.24 0.259 0.0163 0.27 0.3607 0.9975 1235682 TimTec1_000250 CCc1nc2[nH]nc(N)c2c3CC(C)(C)OCc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L09 compound treatment 0.238 -0.00844 -0.12 0.179 -0.0637 -1.07 -0.8416 -0.7819 3081877 TimTec1_000251 O=C(/C=C/N1CCOCC1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L10 compound treatment 0.253 0.00656 0.09 0.264 0.0213 0.36 0.3189 0.8636 3210003 TimTec1_000252 C[n+]1ccc(/C=C/c2cccs2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L11 compound treatment 0.239 -0.00744 -0.11 0.245 0.00228 0.04 -0.0482 -0.4259 1338690 TimTec1_000253 CN(C)Cc1c(O)ccc2occ(C(=O)c3ccc(C)cc3)c12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L12 compound treatment 0.231 -0.0154 -0.22 0.244 0.00128 0.02 -0.1409 -0.6352 1654307 TimTec1_000254 CC1(C)Cc2c(C#N)c3nc(cnn3c2CO1)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L13 compound treatment 0.077 -0.169 -2.42 0.105 -0.138 -2.31 -3.3482 -0.9997 1245793 TimTec1_000255 CCc1oc2ccccc2c1C(=O)c3ccc(OC(=O)C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L14 compound treatment 0.292 0.0456 0.65 0.268 0.0253 0.42 0.7609 0.9784 3081942 TimTec1_000256 CN(C)S(=O)(=O)c1ccc(N/C=C\2/C(=C(C#N)C(=O)N(C)C2=O)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L15 compound treatment 0.048 -0.198 -2.84 0.05 -0.193 -3.23 -4.2942 -0.9979 1570064 TimTec1_000257 Cc1ccc2nc(Nc3ccccc3)cc(C)c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L16 compound treatment 0.302 0.0556 0.79 0.287 0.0443 0.74 1.0875 0.9994 1509985 TimTec1_000258 C=CCC1CCCCC1NC2CCCCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L17 compound treatment 0.302 0.0556 0.79 0.29 0.0473 0.79 1.1231 1.0 1455868 TimTec1_000259 COc1cccc(NC(=O)c2ccc(OC(=S)N3CCC(C)CC3)cc2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L18 compound treatment 0.276 0.0296 0.42 0.263 0.0203 0.34 0.5397 0.9942 3210004 TimTec1_000260 Fc1ccc(/N=C/c2ccc(OC(=O)c3ccco3)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L19 compound treatment 0.226 -0.0204 -0.29 0.232 -0.0107 -0.18 -0.3339 -0.9728 1369950 TimTec1_000261 CCOc1ccc2N(C)C(C)(C)c3ssc(=S)c3-c2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L20 compound treatment 0.118 -0.128 -1.84 0.124 -0.119 -1.99 -2.708 -0.9992 3210005 TimTec1_000262 NC(=O)[C@H]1[C@H](c2ccc(F)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L21 compound treatment 0.303 0.0566 0.81 0.337 0.0943 1.58 1.691 0.9515 1298997 TimTec1_000263 CCOC(=O)c1c(CNc2cccc(c2)C(=O)N)n(C)c3cc(Br)c(OC(=O)C)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L22 compound treatment 0.266 0.0196 0.28 0.332 0.0893 1.5 1.2575 0.8249 1677367 TimTec1_000264 O=C(Nc1c(cnn1c2ccccc2)C(=O)N3CCCCC3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L23 mock treatment 0.25 0.00356 0.05 0.284 0.0413 0.69 0.526 0.7571 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 L24 mock treatment 0.262 0.0156 0.22 0.296 0.0533 0.89 0.7897 0.857 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M01 compound treatment 0.351 0.105 1.5 0.295 0.0523 0.88 1.678 0.9677 1321921 TimTec1_000265 OC1(N(C(=O)Nc2ccccc21)c3ccccc3)C(=O)NCC=C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M02 compound treatment 0.256 0.00956 0.14 0.308 0.0653 1.1 0.8715 0.7893 3081949 TimTec1_000266 CCC1(C)C/C(=C\C)/C(=C(N)C1(C#N)C#N)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M03 compound treatment 0.244 -0.00244 -0.03 0.265 0.0223 0.37 0.2398 0.6384 1666559 TimTec1_000267 COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccco3)cc2)ncn1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M04 compound treatment 0.229 -0.0174 -0.25 0.249 0.00628 0.11 -0.1018 -0.376 1006470 TimTec1_000268 C[N+](C)(Cc1ccccc1)Cc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M05 compound treatment 0.074 -0.172 -2.47 0.089 -0.154 -2.58 -3.5684 -0.9997 3210006 TimTec1_000269 O=S(N1CCOCC1)c2nc3ccccc3s2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M06 compound treatment 0.268 0.0216 0.31 0.261 0.0183 0.31 0.4351 1.0 3081952 TimTec1_000270 S=C(Nc1ccccc1)N=S(c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M07 compound treatment 0.279 0.0326 0.47 0.299 0.0563 0.94 0.9973 0.9469 1489996 TimTec1_000271 COC1OC2COC(OC2CC1O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M08 compound treatment 0.277 0.0306 0.44 0.256 0.0133 0.22 0.4667 0.9512 3210007 TimTec1_000272 O=C(c1ccccc1)c2cc[n+](Cc3ccccn3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M09 compound treatment 0.314 0.0676 0.97 0.299 0.0563 0.94 1.3513 0.9999 3210008 TimTec1_000273 Cc1ccc(/C=C/C(=O)NC(=S)N2CCN(CC2)c3ccc(F)cc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M10 compound treatment 0.289 0.0426 0.61 0.299 0.0563 0.94 1.0984 0.9774 1433383 TimTec1_000274 CCCOC(=S)NC1OCC(O)C(O)C1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M11 compound treatment 0.208 -0.0384 -0.55 0.21 -0.0327 -0.55 -0.7771 -1.0 1720341 TimTec1_000275 O=C(Nc1ccc(cc1)c2ccccc2)C3CC3c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M12 compound treatment 0.263 0.0166 0.24 0.257 0.0143 0.24 0.337 1.0 3081955 TimTec1_000276 COc1ccc(/C=C/C(=O)NC(C)(C)C)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M13 compound treatment 0.251 0.00456 0.07 0.29 0.0473 0.79 0.6073 0.7627 1475730 TimTec1_000277 CCOC(=O)c1nonc1N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M14 compound treatment 0.267 0.0206 0.29 0.283 0.0403 0.68 0.686 0.9305 3082017 TimTec1_000278 Clc1ccc(cc1)C2=NN=C(SC2)N3CCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M15 compound treatment 0.237 -0.00944 -0.13 0.284 0.0413 0.69 0.3945 0.5588 1344248 TimTec1_000279 CCN(CC)CCC(O)(C1CCCCC1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M16 compound treatment 0.297 0.0506 0.72 0.247 0.00428 0.07 0.5622 0.7736 1532600 TimTec1_000280 Cc1nc2ccccc2cc1C(=O)N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M17 compound treatment 0.311 0.0646 0.92 0.303 0.0603 1.01 1.3684 0.999 3210120 TimTec1_000281 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)NCCN4CCOCC4)C(F)(F)F 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M18 compound treatment 0.263 0.0166 0.24 0.283 0.0403 0.68 0.6456 0.9012 1325986 TimTec1_000282 Cc1ccc(o1)C(=O)c2coc3ccc(O)cc23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M19 compound treatment 0.293 0.0466 0.67 0.314 0.0713 1.2 1.3169 0.9618 3210121 TimTec1_000283 OCC(CO)(CO)NC=C1C(=O)c2ccccc2C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M20 compound treatment 0.211 -0.0354 -0.51 0.217 -0.0257 -0.43 -0.6637 -0.9968 1295715 TimTec1_000284 OC(=O)CCCc1cc2cc(Br)ccc2o1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M21 compound treatment 0.271 0.0246 0.35 0.238 -0.00472 -0.08 0.1924 0.5343 3210122 TimTec1_000285 Brc1ccc(/N=C(\c2ccccc2)/c3ccncc3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M22 compound treatment 0.259 0.0126 0.18 0.219 -0.0237 -0.4 -0.1544 -0.3536 1536799 TimTec1_000286 Clc1cccc(NC(=O)NCCN2CCCCC2)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M23 mock treatment 0.276 0.0296 0.42 0.266 0.0233 0.39 0.5753 0.9992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 M24 mock treatment 0.226 -0.0204 -0.29 0.285 0.0423 0.71 0.2951 0.3845 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N01 compound treatment 0.224 -0.0224 -0.32 0.265 0.0223 0.37 0.0375 0.0761 1530149 TimTec1_000287 CCCCN1CCC(CC1)(Nc2ccccc2)C#N 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N02 compound treatment 0.227 -0.0194 -0.28 0.285 0.0423 0.71 0.3052 0.4004 1146434 TimTec1_000288 O=C(COC(=O)c1ccc(cc1)N2C(=O)c3ccccc3C2=O)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N03 compound treatment 0.232 -0.0144 -0.21 0.252 0.00928 0.16 -0.0359 -0.1387 1353615 TimTec1_000289 CCOC(=O)c1c(CN(CC)CC)oc2ccc(OC)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N04 compound treatment 0.254 0.00756 0.11 0.232 -0.0107 -0.18 -0.0507 -0.2416 1022729 TimTec1_000290 O=C1N(C2c3ccccc3Oc4ccccc24)C(=O)c5ccccc15 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N05 compound treatment 0.242 -0.00444 -0.06 0.224 -0.0187 -0.31 -0.267 -0.8331 3082023 TimTec1_000291 O=C1N(/N=C/c2ccccc2)C(=O)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N06 compound treatment 0.296 0.0496 0.71 0.257 0.0143 0.24 0.6708 0.8963 3210123 TimTec1_000292 O=C(CSc1ccccn1)Nc2ccccn2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N07 compound treatment 0.275 0.0286 0.41 0.269 0.0263 0.44 0.6008 0.9993 3082025 TimTec1_000293 Cc1cc(n[nH]1)c2cc(C)[nH]n2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N08 compound treatment 0.299 0.0526 0.75 0.248 0.00528 0.09 0.5943 0.785 1617345 TimTec1_000294 CN1CCc2c(C1)c(NCCO)nc3[nH]nc(N)c23 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N09 compound treatment 0.239 -0.00744 -0.11 0.176 -0.0667 -1.12 -0.867 -0.7708 1226159 TimTec1_000295 C(Cc1ccncc1)Nc2ccc(OCc3ccccc3)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N10 compound treatment 0.222 -0.0244 -0.35 0.24 -0.00272 -0.05 -0.2794 -0.7927 3210124 TimTec1_000296 COc1ccc2c(C)nc(N/C(=N/C(=O)C)/N)nc2c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N11 compound treatment 0.266 0.0196 0.28 0.286 0.0433 0.73 0.7115 0.914 1294429 TimTec1_000297 CC(=O)Nc1c(oc2ccc(Br)cc12)C(=O)O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N12 compound treatment 0.171 -0.0754 -1.08 0.145 -0.0977 -1.64 -1.9227 -0.9794 3210125 TimTec1_000298 CC1(C)Cc2c(C#N)c(=S)[nH]c(N3CCOCC3)c2CS1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N13 compound treatment 0.305 0.0586 0.84 0.25 0.00728 0.12 0.6787 0.8018 1155921 TimTec1_000299 N#CC(CCN1CCN(CC1)c2ccccc2)(c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N14 compound treatment 0.314 0.0676 0.97 0.252 0.00928 0.16 0.7935 0.8106 1441186 TimTec1_000300 C1CCC(CC1)c2nnc(o2)c3ccco3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N15 compound treatment 0.304 0.0576 0.82 0.289 0.0463 0.78 1.1315 0.9996 3210126 TimTec1_000301 CCC(C)C1=NN(C(=O)c2ccccc2)C(O)(C1)C(=O)OC 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N16 compound treatment 0.316 0.0696 0.99 0.32 0.0773 1.3 1.6208 0.9914 3082032 TimTec1_000302 Cc1ccc(cc1)c2ccc(OC(=O)c3ccccc3F)cc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N17 compound treatment 0.272 0.0256 0.37 0.303 0.0603 1.01 0.974 0.9053 1424431 TimTec1_000303 CC1=CC(C)(C)N(Cc2ccccc2)c3ccccc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N18 compound treatment 0.299 0.0526 0.75 0.312 0.0693 1.16 1.3539 0.9777 3081117 TimTec1_000304 Fc1ccc(/N=C/c2ccc(OC(=O)c3cccs3)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N19 compound treatment 0.178 -0.0684 -0.98 0.212 -0.0307 -0.52 -1.0568 -0.9552 3210127 TimTec1_000305 CC(C)C(=O)N1c2ccc(C)cc2-c3c(ssc3=S)C1(C)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N20 compound treatment 0.3 0.0536 0.77 0.28 0.0373 0.63 0.9842 0.995 3081119 TimTec1_000306 CCOc1cc(/C=C/2\SCOC2=O)ccc1O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N21 compound treatment 0.255 0.00856 0.12 0.248 0.00528 0.09 0.1493 0.9874 1693566 TimTec1_000307 CCOC(=O)c1c(C)n(C)c2ccc(O)c(c12)S(=O)(=O)c3ccc(C)cc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N22 compound treatment 0.262 0.0156 0.22 0.286 0.0433 0.73 0.6711 0.8832 1465551 TimTec1_000308 Fc1ccc(CC(=O)NC2CCCCC2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N23 mock treatment 0.259 0.0126 0.18 0.27 0.0273 0.46 0.4508 0.9165 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 N24 mock treatment 0.271 0.0246 0.35 0.258 0.0153 0.26 0.4298 0.988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O01 compound treatment 0.21 -0.0364 -0.52 0.287 0.0443 0.74 0.157 0.173 1586093 TimTec1_000309 OC1(N(C(=O)Nc2ccccc21)c3ccccc3)C(=O)N4CCCCC4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O02 compound treatment 0.233 -0.0134 -0.19 0.279 0.0363 0.61 0.2947 0.4615 1502323 TimTec1_000310 Nc1nc2CCCc2c(c1C#N)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O03 compound treatment 0.252 0.00556 0.08 0.243 2.81E-4 0.0 0.0596 0.7477 3210128 TimTec1_000311 NC(=N)NS(=O)(=O)c1ccc(NC(=S)NC(=O)/C=C/c2ccc(F)cc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O04 compound treatment 0.265 0.0186 0.27 0.28 0.0373 0.63 0.6302 0.9271 1176923 TimTec1_000312 C[N+](C)(CCC#N)Cc1cccc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O05 compound treatment 0.042 -0.204 -2.92 0.045 -0.198 -3.32 -4.4143 -0.998 3081123 TimTec1_000313 S=C(SN1CCOCC1)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O06 compound treatment 0.245 -0.00144 -0.02 0.28 0.0373 0.63 0.4279 0.6835 1002693 TimTec1_000314 COC1OC2COC(OC2C(O)C1O)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O07 compound treatment 0.257 0.0106 0.15 0.256 0.0133 0.22 0.2645 0.9821 1507393 TimTec1_000315 CCCOC(=S)NC1OCC(OC(=O)C)C(OC(=O)C)C1OC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O08 compound treatment 0.257 0.0106 0.15 0.244 0.00128 0.02 0.122 0.7997 3081125 TimTec1_000316 C(c1ccccc1)c2ccc[n+](Cc3ccccn3)c2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O09 compound treatment 0.229 -0.0174 -0.25 0.247 0.00428 0.07 -0.1256 -0.4837 3210129 TimTec1_000317 Cc1cc(C)n(n1)C(=O)COc2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O10 compound treatment 0.268 0.0216 0.31 0.281 0.0383 0.64 0.6724 0.9435 1676440 TimTec1_000318 CC12CCC3C(CC=C4CC(CCC34C)OC5CCCCO5)C2CCC1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O11 compound treatment 0.257 0.0106 0.15 0.285 0.0423 0.71 0.6086 0.8388 1921096 TimTec1_000319 O=C1NC(=O)C2(COC(OC2)c3ccccc3)S1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O12 compound treatment 0.272 0.0256 0.37 0.318 0.0753 1.26 1.152 0.8758 3081128 TimTec1_000320 COc1ccc(/C=C/C(=O)NCc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O13 compound treatment 0.263 0.0166 0.24 0.259 0.0163 0.27 0.3607 0.9975 3081129 TimTec1_000321 COc1nonc1NC(=O)C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O14 compound treatment 0.248 0.00156 0.02 0.256 0.0133 0.22 0.1734 0.7741 1215803 TimTec1_000322 CN(C)CCSc1nc2ccccc2c(=O)n1c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O15 compound treatment 0.225 -0.0214 -0.31 0.289 0.0463 0.78 0.3324 0.3981 1134169 TimTec1_000323 COc1ccc(c2nc3nnc(C)n3[nH]2)c(OC)c1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O16 compound treatment 0.226 -0.0204 -0.29 0.227 -0.0157 -0.26 -0.3933 -0.9987 1165035 TimTec1_000324 CCOC(=O)c1c(CN2CCCCC2)n(c3ccccc3)c4ccc(OC(=O)C)cc14 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O17 compound treatment 0.228 -0.0184 -0.26 0.242 -7.19E-4 -0.01 -0.195 -0.7387 3210130 TimTec1_000325 CC(=O)Nc1ccc(/N=C/c2ccc(cc2)N3CCOCC3)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O18 compound treatment 0.248 0.00156 0.02 0.252 0.00928 0.16 0.126 0.8004 1656585 TimTec1_000326 OC(=O)C(Cc1ccsc1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O19 compound treatment 0.246 -4.38E-4 -0.01 0.299 0.0563 0.94 0.6635 0.7024 3081133 TimTec1_000327 CC1(C)CC(=O)C(=CNC(CO)(CO)CO)C(=O)C1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O20 compound treatment 0.233 -0.0134 -0.19 0.31 0.0673 1.13 0.6626 0.5784 3210131 TimTec1_000328 CCOC(=O)c1c(CNC(C)C)oc2ccc(OC)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O21 compound treatment 0.233 -0.0134 -0.19 0.236 -0.00672 -0.11 -0.2156 -0.9677 3210132 TimTec1_000329 Cc1ccc(C)c(c1)[C@H]2[C@@H](N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O22 compound treatment 0.213 -0.0334 -0.48 0.225 -0.0177 -0.3 -0.5485 -0.9739 1145302 TimTec1_000330 CCOC(=O)c1c(C)n(C2CCCCC2)c3ccc(O)cc13 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O23 mock treatment 0.227 -0.0194 -0.28 0.251 0.00828 0.14 -0.0983 -0.3163 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 O24 mock treatment 0.297 0.0506 0.72 0.308 0.0653 1.1 1.2862 0.9797 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P01 compound treatment 0.219 -0.0274 -0.39 0.287 0.0443 0.74 0.248 0.2951 1004729 TimTec1_000331 COC(=O)c1ccccc1C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P02 compound treatment 0.254 0.00756 0.11 0.31 0.0673 1.13 0.875 0.7713 3210133 TimTec1_000332 O=C(Oc1cc(OC(=O)c2ccco2)cc(OC(=O)c3ccco3)c1)c4ccco4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P03 compound treatment 0.26 0.0136 0.19 0.308 0.0653 1.1 0.9119 0.8196 3081813 TimTec1_000333 CCOC(=O)Cc1c(SC)c2ccccc2n1C 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P04 compound treatment 0.274 0.0276 0.39 0.263 0.0203 0.34 0.5195 0.9973 3081814 TimTec1_000334 CCN(CC)CCOc1ccccc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P05 compound treatment 0.266 0.0196 0.28 0.275 0.0323 0.54 0.581 0.9527 3210134 TimTec1_000335 O=C(Cc1ccccc1)c2cccs2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P06 compound treatment 0.285 0.0386 0.55 0.255 0.0123 0.21 0.5358 0.9099 1158366 TimTec1_000336 O=C(Nc1ccccc1)C(=S)N2CCOCC2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P07 compound treatment 0.287 0.0406 0.58 0.258 0.0153 0.26 0.5916 0.9326 1365315 TimTec1_000337 CCOC(=O)c1c(COC(=O)C)n(C)c2cc(Br)c(OC)cc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P08 compound treatment 0.255 0.00856 0.12 0.263 0.0203 0.34 0.3273 0.9047 1268733 TimTec1_000338 Nc1c(N2CCN(CC2)c3ccccc3)c4ccccc4oc1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P09 compound treatment 0.256 0.00956 0.14 0.258 0.0153 0.26 0.2781 0.9567 1047274 TimTec1_000339 CC(=O)Nc1ccc(OCc2ccccc2)cc1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P10 compound treatment 0.292 0.0456 0.65 0.286 0.0433 0.73 0.9745 0.9985 1459196 TimTec1_000340 CCSc1nnc-2c(OC3(Nc4ccccc42)C(=O)Nc5ccc(Br)cc53)n1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P11 compound treatment 0.273 0.0266 0.38 0.288 0.0453 0.76 0.8061 0.9487 1347458 TimTec1_000341 CCOC(=O)c1oc2ccccc2c1NC(=O)CCN3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P12 compound treatment 0.287 0.0406 0.58 0.319 0.0763 1.28 1.3156 0.9359 1693186 TimTec1_000342 Cc1nn2c(=O)c3CCCc3[nH]c2c1c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P13 compound treatment 0.29 0.0436 0.62 0.294 0.0513 0.86 1.0492 0.9874 1228757 TimTec1_000343 CC1(C)CC(=O)c2c(c([nH]c2C1)c3ccccc3)c4ccccc4 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P14 compound treatment 0.25 0.00356 0.05 0.237 -0.00572 -0.1 -0.0318 -0.293 3081883 TimTec1_000344 NCCCc1nc2cc3sc(CCCN)nc3cc2s1 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P15 compound treatment 0.283 0.0366 0.52 0.294 0.0513 0.86 0.9784 0.9715 1650512 TimTec1_000345 CC1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P16 compound treatment 0.281 0.0346 0.49 0.266 0.0233 0.39 0.6259 0.9932 3081885 TimTec1_000346 N#Cc1ccc(C#N)c(c1)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P17 compound treatment 0.249 0.00256 0.04 0.257 0.0143 0.24 0.1954 0.8059 3081886 TimTec1_000347 Cc1ccc(cc1)C2=C/C(=C/3\OC(=O)c4ccccc34)/C(=O)O2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P18 compound treatment 0.285 0.0386 0.55 0.26 0.0173 0.29 0.5951 0.955 3210253 TimTec1_000348 COC(=O)NC(Nc1ccccc1C(F)(F)F)C(=O)c2ccccc2 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P19 compound treatment 0.259 0.0126 0.18 0.305 0.0623 1.05 0.8662 0.8167 1111738 TimTec1_000349 Cc1nc(NC(=N)N)nc2ccccc12 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P20 compound treatment 0.261 0.0146 0.21 0.246 0.00328 0.06 0.1862 0.8644 1449841 TimTec1_000350 OC(=O)CCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P21 compound treatment 0.305 0.0586 0.84 0.355 0.112 1.88 1.9249 0.9334 1530469 TimTec1_000351 O=C(CSc1nc2ccccc2s1)NC3CCCCC3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P22 compound treatment 0.257 0.0106 0.15 0.291 0.0483 0.81 0.6798 0.8247 1494539 TimTec1_000352 CCCN(CCC)C(=O)c1cnn(c1NC(=O)c2ccccc2)c3ccccc3 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P23 mock treatment 0.312 0.0656 0.94 0.299 0.0563 0.94 1.3311 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.2063 P24 mock treatment 0.274 0.0276 0.39 0.239 -0.00372 -0.06 0.2346 0.5878 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A01 mock treatment 0.266 -0.0337 -0.48 0.245 -0.0412 -0.69 -0.8297 -0.9846 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A02 mock treatment 0.295 -0.00474 -0.07 0.263 -0.0232 -0.39 -0.3228 -0.818 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A03 mock treatment 0.295 -0.00474 -0.07 0.292 0.00584 0.1 0.0214 0.1797 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A04 mock treatment 0.296 -0.00374 -0.05 0.295 0.00884 0.15 0.0671 0.4257 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A05 mock treatment 0.288 -0.0117 -0.17 0.265 -0.0212 -0.36 -0.3698 -0.9415 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A06 mock treatment 0.286 -0.0137 -0.2 0.278 -0.00816 -0.14 -0.2358 -0.9844 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A07 mock treatment 0.326 0.0263 0.38 0.285 -0.00116 -0.02 0.2519 0.6696 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A08 mock treatment 0.301 0.00126 0.02 0.307 0.0208 0.35 0.2601 0.7427 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A09 mock treatment 0.323 0.0233 0.33 0.28 -0.00616 -0.1 0.1622 0.4655 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A10 mock treatment 0.316 0.0163 0.23 0.252 -0.0342 -0.57 -0.2409 -0.3894 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A11 mock treatment 0.324 0.0243 0.35 0.259 -0.0272 -0.46 -0.0769 -0.1343 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A12 mock treatment 0.308 0.00826 0.12 0.263 -0.0232 -0.39 -0.1913 -0.4708 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A13 mock treatment 0.27 -0.0297 -0.43 0.256 -0.0302 -0.51 -0.6587 -0.9963 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A14 mock treatment 0.247 -0.0527 -0.75 0.24 -0.0462 -0.77 -1.0812 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A15 mock treatment 0.278 -0.0217 -0.31 0.256 -0.0302 -0.51 -0.5778 -0.9726 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A16 mock treatment 0.306 0.00626 0.09 0.294 0.00784 0.13 0.1564 0.9824 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A17 mock treatment 0.313 0.0133 0.19 0.269 -0.0172 -0.29 -0.0695 -0.2015 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A18 mock treatment 0.268 -0.0317 -0.45 0.264 -0.0222 -0.37 -0.584 -0.9951 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A19 mock treatment 0.303 0.00326 0.05 0.26 -0.0262 -0.44 -0.2774 -0.6284 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A20 mock treatment 0.297 -0.00274 -0.04 0.269 -0.0172 -0.29 -0.2313 -0.7959 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A21 mock treatment 0.311 0.0113 0.16 0.277 -0.00916 -0.15 0.0052 0.0235 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A22 mock treatment 0.271 -0.0287 -0.41 0.28 -0.00616 -0.1 -0.3637 -0.8582 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A23 mock treatment 0.263 -0.0367 -0.53 0.242 -0.0442 -0.74 -0.8956 -0.9858 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base A24 mock treatment 0.249 -0.0507 -0.73 0.245 -0.0412 -0.69 -1.0016 -0.9997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B01 mock treatment 0.272 -0.0277 -0.4 0.263 -0.0232 -0.39 -0.5554 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B02 mock treatment 0.303 0.00326 0.05 0.265 -0.0212 -0.36 -0.2181 -0.6089 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B03 mock treatment 0.328 0.0283 0.4 0.281 -0.00516 -0.09 0.2246 0.5433 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B04 mock treatment 0.34 0.0403 0.58 0.291 0.00484 0.08 0.4647 0.799 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B05 mock treatment 0.346 0.0463 0.66 0.311 0.0248 0.42 0.7627 0.9752 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B06 mock treatment 0.312 0.0123 0.18 0.288 0.00184 0.03 0.1459 0.8191 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B07 mock treatment 0.315 0.0153 0.22 0.284 -0.00216 -0.04 0.1288 0.5818 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B08 mock treatment 0.318 0.0183 0.26 0.295 0.00884 0.15 0.2897 0.9641 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B09 mock treatment 0.327 0.0273 0.39 0.275 -0.0112 -0.19 0.1433 0.3313 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B10 mock treatment 0.312 0.0123 0.18 0.285 -0.00116 -0.02 0.1103 0.6249 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B11 mock treatment 0.348 0.0483 0.69 0.329 0.0428 0.72 0.9966 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B12 mock treatment 0.289 -0.0107 -0.15 0.315 0.0288 0.48 0.2337 0.4602 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B13 mock treatment 0.316 0.0163 0.23 0.269 -0.0172 -0.29 -0.0391 -0.1057 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B14 mock treatment 0.298 -0.00174 -0.02 0.297 0.0108 0.18 0.1111 0.605 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B15 mock treatment 0.314 0.0143 0.2 0.282 -0.00416 -0.07 0.0949 0.4401 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B16 mock treatment 0.314 0.0143 0.2 0.279 -0.00716 -0.12 0.0593 0.2505 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B17 mock treatment 0.345 0.0453 0.65 0.293 0.00684 0.11 0.539 0.8197 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B18 mock treatment 0.297 -0.00274 -0.04 0.273 -0.0132 -0.22 -0.1838 -0.8196 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B19 mock treatment 0.334 0.0343 0.49 0.27 -0.0162 -0.27 0.1548 0.2763 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B20 mock treatment 0.308 0.00826 0.12 0.265 -0.0212 -0.36 -0.1675 -0.4476 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B21 mock treatment 0.356 0.0563 0.8 0.276 -0.0102 -0.17 0.4485 0.5452 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B22 mock treatment 0.336 0.0363 0.52 0.303 0.0168 0.28 0.5667 0.9593 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B23 mock treatment 0.312 0.0123 0.18 0.285 -0.00116 -0.02 0.1103 0.6249 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base B24 mock treatment 0.282 -0.0177 -0.25 0.256 -0.0302 -0.51 -0.5373 -0.949 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C01 mock treatment 0.272 -0.0277 -0.4 0.249 -0.0372 -0.62 -0.7215 -0.9761 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C02 mock treatment 0.27 -0.0297 -0.43 0.29 0.00384 0.06 -0.2552 -0.5932 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C03 mock treatment 0.302 0.00226 0.03 0.301 0.0148 0.25 0.199 0.7924 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C04 mock treatment 0.328 0.0283 0.4 0.304 0.0178 0.3 0.4976 0.9891 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C05 mock treatment 0.318 0.0183 0.26 0.321 0.0348 0.58 0.5982 0.934 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C06 mock treatment 0.329 0.0293 0.42 0.297 0.0108 0.18 0.4246 0.9304 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C07 mock treatment 0.334 0.0343 0.49 0.272 -0.0142 -0.24 0.1785 0.3277 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C08 mock treatment 0.306 0.00626 0.09 0.29 0.00384 0.06 0.1089 0.987 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C09 mock treatment 0.312 0.0123 0.18 0.287 8.41E-4 0.01 0.134 0.7616 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C10 mock treatment 0.343 0.0433 0.62 0.295 0.00884 0.15 0.5425 0.8525 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C11 mock treatment 0.323 0.0233 0.33 0.307 0.0208 0.35 0.4826 0.9997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C12 mock treatment 0.341 0.0413 0.59 0.283 -0.00316 -0.05 0.3799 0.641 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C13 mock treatment 0.312 0.0123 0.18 0.288 0.00184 0.03 0.1459 0.8191 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C14 mock treatment 0.339 0.0393 0.56 0.284 -0.00216 -0.04 0.3715 0.6601 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C15 mock treatment 0.314 0.0143 0.2 0.259 -0.0272 -0.46 -0.1781 -0.3565 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C16 mock treatment 0.307 0.00726 0.1 0.247 -0.0392 -0.66 -0.3913 -0.588 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C17 mock treatment 0.326 0.0263 0.38 0.257 -0.0292 -0.49 -0.0804 -0.1304 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C18 mock treatment 0.322 0.0223 0.32 0.279 -0.00716 -0.12 0.1402 0.412 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C19 mock treatment 0.291 -0.00874 -0.12 0.298 0.0118 0.2 0.0522 0.2222 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C20 mock treatment 0.29 -0.00974 -0.14 0.295 0.00884 0.15 0.0065 0.0317 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C21 mock treatment 0.326 0.0263 0.38 0.251 -0.0352 -0.59 -0.1516 -0.2168 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C22 mock treatment 0.266 -0.0337 -0.48 0.236 -0.0502 -0.84 -0.9365 -0.9651 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C23 mock treatment 0.291 -0.00874 -0.12 0.286 -1.59E-4 0.0 -0.0902 -0.722 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base C24 mock treatment 0.225 -0.0747 -1.07 0.246 -0.0402 -0.67 -1.2325 -0.9753 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D01 mock treatment 0.272 -0.0277 -0.4 0.255 -0.0312 -0.52 -0.6503 -0.9907 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D02 mock treatment 0.306 0.00626 0.09 0.271 -0.0152 -0.25 -0.1166 -0.4321 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D03 mock treatment 0.319 0.0193 0.28 0.259 -0.0272 -0.46 -0.1275 -0.2393 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D04 mock treatment 0.344 0.0443 0.63 0.347 0.0608 1.02 1.1698 0.9736 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D05 mock treatment 0.365 0.0653 0.93 0.338 0.0518 0.87 1.2753 0.9994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D06 mock treatment 0.371 0.0713 1.02 0.329 0.0428 0.72 1.2292 0.9854 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D07 mock treatment 0.355 0.0553 0.79 0.316 0.0298 0.5 0.9131 0.9758 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D08 mock treatment 0.334 0.0343 0.49 0.311 0.0248 0.42 0.6414 0.9968 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D09 mock treatment 0.336 0.0363 0.52 0.31 0.0238 0.4 0.6497 0.9918 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D10 mock treatment 0.352 0.0523 0.75 0.32 0.0338 0.57 0.9302 0.9908 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D11 mock treatment 0.338 0.0383 0.55 0.333 0.0468 0.79 0.9429 0.9843 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D12 mock treatment 0.354 0.0543 0.78 0.354 0.0678 1.14 1.354 0.9826 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D13 mock treatment 0.332 0.0323 0.46 0.329 0.0428 0.72 0.8348 0.977 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D14 mock treatment 0.335 0.0353 0.5 0.303 0.0168 0.28 0.5565 0.9625 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D15 mock treatment 0.335 0.0353 0.5 0.28 -0.00616 -0.1 0.2836 0.5507 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D16 mock treatment 0.336 0.0363 0.52 0.303 0.0168 0.28 0.5667 0.9593 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D17 mock treatment 0.344 0.0443 0.63 0.274 -0.0122 -0.2 0.3034 0.4561 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D18 mock treatment 0.331 0.0313 0.45 0.335 0.0488 0.82 0.8959 0.9594 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D19 mock treatment 0.34 0.0403 0.58 0.332 0.0458 0.77 0.9513 0.9898 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D20 mock treatment 0.33 0.0303 0.43 0.306 0.0198 0.33 0.5416 0.9916 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D21 mock treatment 0.312 0.0123 0.18 0.302 0.0158 0.27 0.312 0.9796 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D22 mock treatment 0.336 0.0363 0.52 0.323 0.0368 0.62 0.804 0.9962 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D23 mock treatment 0.304 0.00426 0.06 0.269 -0.0172 -0.29 -0.1605 -0.5453 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base D24 mock treatment 0.264 -0.0357 -0.51 0.256 -0.0302 -0.51 -0.7194 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E01 mock treatment 0.27 -0.0297 -0.43 0.255 -0.0312 -0.52 -0.6706 -0.9947 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E02 mock treatment 0.309 0.00926 0.13 0.278 -0.00816 -0.14 -0.0031 -0.0165 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E03 mock treatment 0.286 -0.0137 -0.2 0.296 0.00984 0.17 -0.0221 -0.0862 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E04 mock treatment 0.3 2.64E-4 0.0 0.319 0.0328 0.55 0.3924 0.7119 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E05 mock treatment 0.294 -0.00574 -0.08 0.308 0.0218 0.37 0.2012 0.5356 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E06 mock treatment 0.329 0.0293 0.42 0.281 -0.00516 -0.09 0.2348 0.5492 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E07 mock treatment 0.336 0.0363 0.52 0.315 0.0288 0.48 0.7091 0.9994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E08 mock treatment 0.323 0.0233 0.33 0.303 0.0168 0.28 0.4352 0.9967 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E09 mock treatment 0.323 0.0233 0.33 0.308 0.0218 0.37 0.4945 0.9988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E10 mock treatment 0.339 0.0393 0.56 0.316 0.0298 0.5 0.7513 0.9984 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E11 mock treatment 0.324 0.0243 0.35 0.296 0.00984 0.17 0.3622 0.9424 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E12 mock treatment 0.32 0.0203 0.29 0.308 0.0218 0.37 0.4642 0.9932 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E13 mock treatment 0.3 2.64E-4 0.0 0.307 0.0208 0.35 0.25 0.7147 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E14 mock treatment 0.337 0.0373 0.53 0.31 0.0238 0.4 0.6598 0.99 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E15 mock treatment 0.33 0.0303 0.43 0.296 0.00984 0.17 0.4229 0.9127 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E16 mock treatment 0.305 0.00526 0.08 0.311 0.0248 0.42 0.3481 0.8215 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E17 mock treatment 0.309 0.00926 0.13 0.315 0.0288 0.48 0.436 0.8687 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E18 mock treatment 0.315 0.0153 0.22 0.333 0.0468 0.79 0.7103 0.8705 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E19 mock treatment 0.303 0.00326 0.05 0.317 0.0308 0.52 0.399 0.7678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E20 mock treatment 0.304 0.00426 0.06 0.254 -0.0322 -0.54 -0.3385 -0.6232 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E21 mock treatment 0.309 0.00926 0.13 0.274 -0.0122 -0.2 -0.0506 -0.208 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E22 mock treatment 0.299 -7.36E-4 -0.01 0.28 -0.00616 -0.1 -0.0805 -0.7751 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E23 mock treatment 0.266 -0.0337 -0.48 0.249 -0.0372 -0.62 -0.7822 -0.992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base E24 mock treatment 0.249 -0.0507 -0.73 0.226 -0.0602 -1.01 -1.2271 -0.9869 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F01 mock treatment 0.286 -0.0137 -0.2 0.261 -0.0252 -0.42 -0.4375 -0.9394 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F02 mock treatment 0.304 0.00426 0.06 0.261 -0.0252 -0.42 -0.2555 -0.5988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F03 mock treatment 0.297 -0.00274 -0.04 0.309 0.0228 0.38 0.2434 0.6316 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F04 mock treatment 0.32 0.0203 0.29 0.29 0.00384 0.06 0.2505 0.8438 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F05 mock treatment 0.357 0.0573 0.82 0.332 0.0458 0.77 1.1232 0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F06 mock treatment 0.349 0.0493 0.7 0.323 0.0368 0.62 0.9355 0.9979 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F07 mock treatment 0.315 0.0153 0.22 0.315 0.0288 0.48 0.4967 0.9353 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F08 mock treatment 0.318 0.0183 0.26 0.317 0.0308 0.52 0.5507 0.9499 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F09 mock treatment 0.336 0.0363 0.52 0.338 0.0518 0.87 0.982 0.9694 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F10 mock treatment 0.349 0.0493 0.7 0.326 0.0398 0.67 0.9711 0.9997 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F11 mock treatment 0.325 0.0253 0.36 0.341 0.0548 0.92 0.9064 0.9166 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F12 mock treatment 0.338 0.0383 0.55 0.28 -0.00616 -0.1 0.3139 0.5636 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F13 mock treatment 0.323 0.0233 0.33 0.306 0.0198 0.33 0.4708 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F14 mock treatment 0.341 0.0413 0.59 0.32 0.0338 0.57 0.819 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F15 mock treatment 0.313 0.0133 0.19 0.327 0.0408 0.69 0.6189 0.8701 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F16 mock treatment 0.338 0.0383 0.55 0.315 0.0288 0.48 0.7293 0.9981 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F17 mock treatment 0.351 0.0513 0.73 0.331 0.0448 0.75 1.0507 0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F18 mock treatment 0.319 0.0193 0.28 0.281 -0.00516 -0.09 0.1336 0.4626 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F19 mock treatment 0.321 0.0213 0.3 0.315 0.0288 0.48 0.5574 0.9749 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F20 mock treatment 0.293 -0.00674 -0.1 0.279 -0.00716 -0.12 -0.1531 -0.994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F21 mock treatment 0.348 0.0483 0.69 0.293 0.00684 0.11 0.5693 0.8135 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F22 mock treatment 0.321 0.0213 0.3 0.284 -0.00216 -0.04 0.1894 0.6185 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F23 mock treatment 0.289 -0.0107 -0.15 0.28 -0.00616 -0.1 -0.1817 -0.9814 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base F24 mock treatment 0.261 -0.0387 -0.55 0.233 -0.0532 -0.89 -1.0227 -0.9737 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G01 mock treatment 0.243 -0.0567 -0.81 0.241 -0.0452 -0.76 -1.1098 -0.9994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G02 mock treatment 0.301 0.00126 0.02 0.288 0.00184 0.03 0.0346 0.9674 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G03 mock treatment 0.302 0.00226 0.03 0.26 -0.0262 -0.44 -0.2876 -0.6532 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G04 mock treatment 0.323 0.0233 0.33 0.274 -0.0122 -0.2 0.091 0.2331 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G05 mock treatment 0.299 -7.36E-4 -0.01 0.271 -0.0152 -0.25 -0.1874 -0.7357 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G06 mock treatment 0.316 0.0163 0.23 0.312 0.0258 0.43 0.4712 0.9574 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G07 mock treatment 0.315 0.0153 0.22 0.303 0.0168 0.28 0.3543 0.9919 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G08 mock treatment 0.301 0.00126 0.02 0.31 0.0238 0.4 0.2957 0.7383 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G09 mock treatment 0.302 0.00226 0.03 0.316 0.0298 0.5 0.3771 0.7513 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G10 mock treatment 0.314 0.0143 0.2 0.318 0.0318 0.53 0.5222 0.9128 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G11 mock treatment 0.307 0.00726 0.1 0.289 0.00284 0.05 0.1072 0.9376 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G12 mock treatment 0.334 0.0343 0.49 0.308 0.0218 0.37 0.6058 0.9898 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G13 mock treatment 0.289 -0.0107 -0.15 0.296 0.00984 0.17 0.0082 0.0364 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G14 mock treatment 0.332 0.0323 0.46 0.319 0.0328 0.55 0.7161 0.9961 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G15 mock treatment 0.318 0.0183 0.26 0.281 -0.00516 -0.09 0.1235 0.4487 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G16 mock treatment 0.293 -0.00674 -0.1 0.287 8.41E-4 0.01 -0.0581 -0.5971 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G17 mock treatment 0.303 0.00326 0.05 0.305 0.0188 0.32 0.2566 0.8028 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G18 mock treatment 0.315 0.0153 0.22 0.294 0.00784 0.13 0.2474 0.9706 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G19 mock treatment 0.292 -0.00774 -0.11 0.276 -0.0102 -0.17 -0.1988 -0.9781 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G20 mock treatment 0.293 -0.00674 -0.1 0.26 -0.0262 -0.44 -0.3786 -0.8422 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G21 mock treatment 0.259 -0.0407 -0.58 0.265 -0.0212 -0.36 -0.6631 -0.9718 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G22 mock treatment 0.264 -0.0357 -0.51 0.276 -0.0102 -0.17 -0.482 -0.8945 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G23 mock treatment 0.258 -0.0417 -0.6 0.262 -0.0242 -0.41 -0.7088 -0.9822 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base G24 mock treatment 0.228 -0.0717 -1.03 0.193 -0.0932 -1.56 -1.8312 -0.9791 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H01 mock treatment 0.285 -0.0147 -0.21 0.267 -0.0192 -0.32 -0.3764 -0.979 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H02 mock treatment 0.277 -0.0227 -0.33 0.272 -0.0142 -0.24 -0.398 -0.9881 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H03 mock treatment 0.284 -0.0157 -0.23 0.257 -0.0292 -0.49 -0.5052 -0.9379 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H04 mock treatment 0.319 0.0193 0.28 0.315 0.0288 0.48 0.5371 0.9643 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H05 mock treatment 0.335 0.0353 0.5 0.327 0.0408 0.69 0.8414 0.9886 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H06 mock treatment 0.325 0.0253 0.36 0.324 0.0378 0.64 0.7046 0.9643 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H07 mock treatment 0.314 0.0143 0.2 0.292 0.00584 0.1 0.2136 0.9436 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H08 mock treatment 0.309 0.00926 0.13 0.294 0.00784 0.13 0.1868 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H09 mock treatment 0.311 0.0113 0.16 0.327 0.0408 0.69 0.5986 0.8501 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H10 mock treatment 0.296 -0.00374 -0.05 0.288 0.00184 0.03 -0.0159 -0.2582 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H11 mock treatment 0.322 0.0223 0.32 0.306 0.0198 0.33 0.4607 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H12 mock treatment 0.309 0.00926 0.13 0.295 0.00884 0.15 0.1986 0.9984 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H13 mock treatment 0.303 0.00326 0.05 0.317 0.0308 0.52 0.399 0.7678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H14 mock treatment 0.321 0.0213 0.3 0.304 0.0178 0.3 0.4268 1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H15 mock treatment 0.295 -0.00474 -0.07 0.285 -0.00116 -0.02 -0.0617 -0.8748 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H16 mock treatment 0.321 0.0213 0.3 0.319 0.0328 0.55 0.6048 0.9607 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H17 mock treatment 0.317 0.0173 0.25 0.307 0.0208 0.35 0.422 0.9855 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H18 mock treatment 0.299 -7.36E-4 -0.01 0.32 0.0338 0.57 0.3942 0.6939 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H19 mock treatment 0.285 -0.0147 -0.21 0.263 -0.0232 -0.39 -0.4239 -0.9587 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H20 mock treatment 0.307 0.00726 0.1 0.293 0.00684 0.11 0.1547 0.9988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H21 mock treatment 0.319 0.0193 0.28 0.299 0.0128 0.22 0.3472 0.9926 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H22 mock treatment 0.284 -0.0157 -0.23 0.292 0.00584 0.1 -0.0898 -0.3659 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H23 mock treatment 0.283 -0.0167 -0.24 0.269 -0.0172 -0.29 -0.3729 -0.9958 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base H24 mock treatment 0.254 -0.0457 -0.65 0.194 -0.0922 -1.55 -1.5563 -0.9267 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I01 mock treatment 0.258 -0.0417 -0.6 0.261 -0.0252 -0.42 -0.7207 -0.9856 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I02 mock treatment 0.279 -0.0207 -0.3 0.302 0.0158 0.27 -0.0217 -0.0545 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I03 mock treatment 0.281 -0.0187 -0.27 0.29 0.00384 0.06 -0.1439 -0.5221 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I04 mock treatment 0.307 0.00726 0.1 0.315 0.0288 0.48 0.4158 0.8398 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I05 mock treatment 0.31 0.0103 0.15 0.306 0.0198 0.33 0.3393 0.9323 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I06 mock treatment 0.31 0.0103 0.15 0.304 0.0178 0.3 0.3155 0.9462 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I07 mock treatment 0.309 0.00926 0.13 0.3 0.0138 0.23 0.258 0.9646 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I08 mock treatment 0.317 0.0173 0.25 0.3 0.0138 0.23 0.3389 0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I09 mock treatment 0.301 0.00126 0.02 0.299 0.0128 0.22 0.1652 0.7637 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I10 mock treatment 0.299 -7.36E-4 -0.01 0.287 8.41E-4 0.01 0.0025 0.144 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I11 mock treatment 0.312 0.0123 0.18 0.282 -0.00416 -0.07 0.0747 0.3956 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I12 mock treatment 0.301 0.00126 0.02 0.284 -0.00216 -0.04 -0.0128 -0.3171 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I13 mock treatment 0.282 -0.0177 -0.25 0.311 0.0248 0.42 0.1154 0.2365 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I14 mock treatment 0.312 0.0123 0.18 0.297 0.0108 0.18 0.2527 0.9998 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I15 mock treatment 0.299 -7.36E-4 -0.01 0.266 -0.0202 -0.34 -0.2467 -0.7288 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I16 mock treatment 0.3 2.64E-4 0.0 0.276 -0.0102 -0.17 -0.1179 -0.6913 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I17 mock treatment 0.276 -0.0237 -0.34 0.264 -0.0222 -0.37 -0.5031 -0.999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I18 mock treatment 0.304 0.00426 0.06 0.295 0.00884 0.15 0.1481 0.9228 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I19 mock treatment 0.31 0.0103 0.15 0.282 -0.00416 -0.07 0.0545 0.335 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I20 mock treatment 0.275 -0.0247 -0.35 0.285 -0.00116 -0.02 -0.2639 -0.7449 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I21 mock treatment 0.258 -0.0417 -0.6 0.289 0.00284 0.05 -0.3884 -0.6486 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I22 mock treatment 0.262 -0.0377 -0.54 0.256 -0.0302 -0.51 -0.7396 -0.9995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I23 mock treatment 0.238 -0.0617 -0.88 0.275 -0.0112 -0.19 -0.7568 -0.8384 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base I24 mock treatment 0.215 -0.0847 -1.21 0.22 -0.0662 -1.11 -1.6422 -0.999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J01 mock treatment 0.313 0.0133 0.19 0.263 -0.0232 -0.39 -0.1407 -0.3253 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J02 mock treatment 0.289 -0.0107 -0.15 0.332 0.0458 0.77 0.4355 0.555 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J03 mock treatment 0.283 -0.0167 -0.24 0.305 0.0188 0.32 0.0543 0.137 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J04 mock treatment 0.296 -0.00374 -0.05 0.317 0.0308 0.52 0.3282 0.6307 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J05 mock treatment 0.334 0.0343 0.49 0.323 0.0368 0.62 0.7838 0.9934 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J06 mock treatment 0.32 0.0203 0.29 0.302 0.0158 0.27 0.393 0.9991 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J07 mock treatment 0.336 0.0363 0.52 0.286 -1.59E-4 0.0 0.3649 0.7035 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J08 mock treatment 0.34 0.0403 0.58 0.286 -1.59E-4 0.0 0.4054 0.7038 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J09 mock treatment 0.333 0.0333 0.48 0.319 0.0328 0.55 0.7262 0.9973 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J10 mock treatment 0.334 0.0343 0.49 0.323 0.0368 0.62 0.7838 0.9934 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J11 mock treatment 0.315 0.0153 0.22 0.295 0.00884 0.15 0.2593 0.9823 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J12 mock treatment 0.328 0.0283 0.4 0.297 0.0108 0.18 0.4145 0.935 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J13 mock treatment 0.319 0.0193 0.28 0.297 0.0108 0.18 0.3235 0.9797 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J14 mock treatment 0.322 0.0223 0.32 0.297 0.0108 0.18 0.3538 0.9648 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J15 mock treatment 0.335 0.0353 0.5 0.304 0.0178 0.3 0.5684 0.969 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J16 mock treatment 0.301 0.00126 0.02 0.319 0.0328 0.55 0.4025 0.7299 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J17 mock treatment 0.332 0.0323 0.46 0.29 0.00384 0.06 0.3719 0.7981 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J18 mock treatment 0.291 -0.00874 -0.12 0.281 -0.00516 -0.09 -0.1496 -0.9839 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J19 mock treatment 0.306 0.00626 0.09 0.288 0.00184 0.03 0.0852 0.899 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J20 mock treatment 0.315 0.0153 0.22 0.304 0.0178 0.3 0.3661 0.9879 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J21 mock treatment 0.3 2.64E-4 0.0 0.293 0.00684 0.11 0.0839 0.7299 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J22 mock treatment 0.277 -0.0227 -0.33 0.252 -0.0342 -0.57 -0.6354 -0.9639 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J23 mock treatment 0.294 -0.00574 -0.08 0.257 -0.0292 -0.49 -0.4041 -0.8143 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base J24 mock treatment 0.267 -0.0327 -0.47 0.213 -0.0732 -1.23 -1.1994 -0.9126 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K01 mock treatment 0.27 -0.0297 -0.43 0.294 0.00784 0.13 -0.2077 -0.4665 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K02 mock treatment 0.278 -0.0217 -0.31 0.274 -0.0122 -0.2 -0.3641 -0.9792 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K03 mock treatment 0.311 0.0113 0.16 0.26 -0.0262 -0.44 -0.1965 -0.4202 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K04 mock treatment 0.27 -0.0297 -0.43 0.285 -0.00116 -0.02 -0.3145 -0.7387 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K05 mock treatment 0.273 -0.0267 -0.38 0.29 0.00384 0.06 -0.2248 -0.5797 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K06 mock treatment 0.289 -0.0107 -0.15 0.294 0.00784 0.13 -0.0155 -0.0768 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K07 mock treatment 0.274 -0.0257 -0.37 0.25 -0.0362 -0.61 -0.6894 -0.9713 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K08 mock treatment 0.284 -0.0157 -0.23 0.269 -0.0172 -0.29 -0.3628 -0.9926 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K09 mock treatment 0.274 -0.0257 -0.37 0.251 -0.0352 -0.59 -0.6776 -0.9742 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K10 mock treatment 0.3 2.64E-4 0.0 0.269 -0.0172 -0.29 -0.201 -0.6978 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K11 mock treatment 0.294 -0.00574 -0.08 0.285 -0.00116 -0.02 -0.0718 -0.8511 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K12 mock treatment 0.302 0.00226 0.03 0.279 -0.00716 -0.12 -0.0621 -0.4988 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K13 mock treatment 0.308 0.00826 0.12 0.253 -0.0332 -0.56 -0.31 -0.5448 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K14 mock treatment 0.298 -0.00174 -0.02 0.293 0.00684 0.11 0.0636 0.5416 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K15 mock treatment 0.301 0.00126 0.02 0.284 -0.00216 -0.04 -0.0128 -0.3171 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K16 mock treatment 0.285 -0.0147 -0.21 0.263 -0.0232 -0.39 -0.4239 -0.9587 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K17 mock treatment 0.32 0.0203 0.29 0.264 -0.0222 -0.37 -0.058 -0.1231 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K18 mock treatment 0.285 -0.0147 -0.21 0.278 -0.00816 -0.14 -0.2459 -0.9782 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K19 mock treatment 0.267 -0.0327 -0.47 0.292 0.00584 0.1 -0.2618 -0.5472 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K20 mock treatment 0.282 -0.0177 -0.25 0.241 -0.0452 -0.76 -0.7153 -0.895 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K21 mock treatment 0.306 0.00626 0.09 0.277 -0.00916 -0.15 -0.0453 -0.2549 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K22 mock treatment 0.262 -0.0377 -0.54 0.254 -0.0322 -0.54 -0.7633 -1.0 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K23 mock treatment 0.279 -0.0207 -0.3 0.245 -0.0412 -0.69 -0.6982 -0.9287 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base K24 mock treatment 0.256 -0.0437 -0.63 0.233 -0.0532 -0.89 -1.0733 -0.9849 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L01 mock treatment 0.281 -0.0187 -0.27 0.266 -0.0202 -0.34 -0.4288 -0.9933 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L02 mock treatment 0.337 0.0373 0.53 0.253 -0.0332 -0.56 -0.0166 -0.0216 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L03 mock treatment 0.319 0.0193 0.28 0.315 0.0288 0.48 0.5371 0.9643 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L04 mock treatment 0.324 0.0243 0.35 0.297 0.0108 0.18 0.3741 0.9546 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L05 mock treatment 0.311 0.0113 0.16 0.304 0.0178 0.3 0.3257 0.9577 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L06 mock treatment 0.3 2.64E-4 0.0 0.299 0.0128 0.22 0.1551 0.7194 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L07 mock treatment 0.297 -0.00274 -0.04 0.32 0.0338 0.57 0.374 0.6568 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L08 mock treatment 0.277 -0.0227 -0.33 0.292 0.00584 0.1 -0.1606 -0.4729 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L09 mock treatment 0.301 0.00126 0.02 0.321 0.0348 0.58 0.4263 0.7286 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L10 mock treatment 0.291 -0.00874 -0.12 0.281 -0.00516 -0.09 -0.1496 -0.9839 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L11 mock treatment 0.29 -0.00974 -0.14 0.302 0.0158 0.27 0.0895 0.2983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L12 mock treatment 0.304 0.00426 0.06 0.276 -0.0102 -0.17 -0.0774 -0.4277 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L13 mock treatment 0.301 0.00126 0.02 0.297 0.0108 0.18 0.1414 0.7735 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L14 mock treatment 0.287 -0.0127 -0.18 0.328 0.0418 0.7 0.3678 0.5069 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L15 mock treatment 0.294 -0.00574 -0.08 0.325 0.0388 0.65 0.403 0.6133 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L16 mock treatment 0.313 0.0133 0.19 0.291 0.00484 0.08 0.1916 0.9284 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L17 mock treatment 0.3 2.64E-4 0.0 0.287 8.41E-4 0.01 0.0126 0.8657 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L18 mock treatment 0.34 0.0403 0.58 0.284 -0.00216 -0.04 0.3816 0.6613 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L19 mock treatment 0.31 0.0103 0.15 0.292 0.00584 0.1 0.1731 0.9807 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L20 mock treatment 0.266 -0.0337 -0.48 0.286 -1.59E-4 0.0 -0.3431 -0.711 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L21 mock treatment 0.295 -0.00474 -0.07 0.275 -0.0112 -0.19 -0.1803 -0.9055 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L22 mock treatment 0.318 0.0183 0.26 0.304 0.0178 0.3 0.3965 0.9977 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L23 mock treatment 0.289 -0.0107 -0.15 0.275 -0.0112 -0.19 -0.241 -0.9951 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base L24 mock treatment 0.221 -0.0787 -1.13 0.232 -0.0542 -0.91 -1.4391 -0.9944 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M01 mock treatment 0.285 -0.0147 -0.21 0.246 -0.0402 -0.67 -0.6257 -0.8859 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M02 mock treatment 0.286 -0.0137 -0.2 0.294 0.00784 0.13 -0.0459 -0.194 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M03 mock treatment 0.297 -0.00274 -0.04 0.279 -0.00716 -0.12 -0.1126 -0.8913 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M04 mock treatment 0.326 0.0263 0.38 0.319 0.0328 0.55 0.6554 0.9825 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M05 mock treatment 0.304 0.00426 0.06 0.294 0.00784 0.13 0.1362 0.9389 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M06 mock treatment 0.296 -0.00374 -0.05 0.295 0.00884 0.15 0.0671 0.4257 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M07 mock treatment 0.051 -0.249 -3.56 0.283 -0.00316 -0.05 -2.5533 -0.7176 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M08 mock treatment 0.288 -0.0117 -0.17 0.293 0.00684 0.11 -0.0375 -0.1844 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M09 mock treatment 0.298 -0.00174 -0.02 0.292 0.00584 0.1 0.0518 0.5118 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M10 mock treatment 0.303 0.00326 0.05 0.303 0.0168 0.28 0.2329 0.8129 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M11 mock treatment 0.296 -0.00374 -0.05 0.317 0.0308 0.52 0.3282 0.6307 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M12 mock treatment 0.271 -0.0287 -0.41 0.319 0.0328 0.55 0.0991 0.1442 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M13 mock treatment 0.262 -0.0377 -0.54 0.297 0.0108 0.18 -0.253 -0.4442 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M14 mock treatment 0.266 -0.0337 -0.48 0.258 -0.0282 -0.47 -0.6754 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M15 mock treatment 0.27 -0.0297 -0.43 0.293 0.00684 0.11 -0.2196 -0.4984 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M16 mock treatment 0.304 0.00426 0.06 0.28 -0.00616 -0.1 -0.03 -0.2497 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M17 mock treatment 0.267 -0.0327 -0.47 0.272 -0.0142 -0.24 -0.4991 -0.9506 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M18 mock treatment 0.316 0.0163 0.23 0.299 0.0128 0.22 0.3169 0.9993 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M19 mock treatment 0.303 0.00326 0.05 0.328 0.0418 0.7 0.5296 0.7525 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M20 mock treatment 0.297 -0.00274 -0.04 0.262 -0.0242 -0.41 -0.3144 -0.7718 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M21 mock treatment 0.299 -7.36E-4 -0.01 0.244 -0.0422 -0.71 -0.5078 -0.7176 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M22 mock treatment 0.26 -0.0397 -0.57 0.273 -0.0132 -0.22 -0.5581 -0.9152 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M23 mock treatment 0.275 -0.0247 -0.35 0.239 -0.0472 -0.79 -0.8099 -0.9341 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base M24 mock treatment 0.225 -0.0747 -1.07 0.221 -0.0652 -1.09 -1.5292 -0.9999 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N01 mock treatment 0.264 -0.0357 -0.51 0.284 -0.00216 -0.04 -0.3871 -0.7553 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N02 mock treatment 0.289 -0.0107 -0.15 0.265 -0.0212 -0.36 -0.3597 -0.9297 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N03 mock treatment 0.317 0.0173 0.25 0.307 0.0208 0.35 0.422 0.9855 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N04 mock treatment 0.291 -0.00874 -0.12 0.33 0.0438 0.74 0.4319 0.5787 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N05 mock treatment 0.296 -0.00374 -0.05 0.323 0.0368 0.62 0.3994 0.6436 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N06 mock treatment 0.305 0.00526 0.08 0.289 0.00284 0.05 0.087 0.9757 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N07 mock treatment 0.301 0.00126 0.02 0.321 0.0348 0.58 0.4263 0.7286 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N08 mock treatment 0.301 0.00126 0.02 0.265 -0.0212 -0.36 -0.2383 -0.6702 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N09 mock treatment 0.303 0.00326 0.05 0.308 0.0218 0.37 0.2922 0.7908 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N10 mock treatment 0.295 -0.00474 -0.07 0.312 0.0258 0.43 0.2588 0.5895 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N11 mock treatment 0.297 -0.00274 -0.04 0.296 0.00984 0.17 0.0891 0.525 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N12 mock treatment 0.298 -0.00174 -0.02 0.279 -0.00716 -0.12 -0.1025 -0.8356 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N13 mock treatment 0.281 -0.0187 -0.27 0.319 0.0328 0.55 0.2003 0.3267 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N14 mock treatment 0.261 -0.0387 -0.55 0.273 -0.0132 -0.22 -0.548 -0.9187 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N15 mock treatment 0.301 0.00126 0.02 0.31 0.0238 0.4 0.2957 0.7383 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N16 mock treatment 0.301 0.00126 0.02 0.29 0.00384 0.06 0.0584 0.8717 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N17 mock treatment 0.297 -0.00274 -0.04 0.314 0.0278 0.47 0.3027 0.6456 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N18 mock treatment 0.282 -0.0177 -0.25 0.309 0.0228 0.38 0.0917 0.1995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N19 mock treatment 0.313 0.0133 0.19 0.326 0.0398 0.67 0.607 0.8733 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N20 mock treatment 0.278 -0.0217 -0.31 0.259 -0.0272 -0.46 -0.5422 -0.9826 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N21 mock treatment 0.282 -0.0177 -0.25 0.332 0.0458 0.77 0.3647 0.4501 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N22 mock treatment 0.283 -0.0167 -0.24 0.267 -0.0192 -0.32 -0.3967 -0.9894 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N23 mock treatment 0.255 -0.0447 -0.64 0.269 -0.0172 -0.29 -0.6561 -0.935 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base N24 mock treatment 0.214 -0.0857 -1.23 0.248 -0.0382 -0.64 -1.32 -0.9541 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O01 mock treatment 0.287 -0.0127 -0.18 0.262 -0.0242 -0.41 -0.4155 -0.9348 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O02 mock treatment 0.284 -0.0157 -0.23 0.284 -0.00216 -0.04 -0.1848 -0.8105 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O03 mock treatment 0.305 0.00526 0.08 0.3 0.0138 0.23 0.2175 0.8907 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O04 mock treatment 0.291 -0.00874 -0.12 0.304 0.0178 0.3 0.1234 0.3802 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O05 mock treatment 0.305 0.00526 0.08 0.313 0.0268 0.45 0.3718 0.814 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O06 mock treatment 0.277 -0.0227 -0.33 0.261 -0.0252 -0.42 -0.5285 -0.9917 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O07 mock treatment 0.298 -0.00174 -0.02 0.285 -0.00116 -0.02 -0.0313 -0.9927 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O08 mock treatment 0.297 -0.00274 -0.04 0.305 0.0188 0.32 0.1959 0.6149 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O09 mock treatment 0.293 -0.00674 -0.1 0.28 -0.00616 -0.1 -0.1412 -0.9994 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O10 mock treatment 0.271 -0.0287 -0.41 0.277 -0.00916 -0.15 -0.3993 -0.91 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O11 mock treatment 0.277 -0.0227 -0.33 0.255 -0.0312 -0.52 -0.5998 -0.9739 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O12 mock treatment 0.298 -0.00174 -0.02 0.294 0.00784 0.13 0.0755 0.5637 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O13 mock treatment 0.278 -0.0217 -0.31 0.256 -0.0302 -0.51 -0.5778 -0.9726 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O14 mock treatment 0.273 -0.0267 -0.38 0.273 -0.0132 -0.22 -0.4266 -0.966 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O15 mock treatment 0.265 -0.0347 -0.5 0.286 -1.59E-4 0.0 -0.3532 -0.7109 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O16 mock treatment 0.279 -0.0207 -0.3 0.283 -0.00316 -0.05 -0.2472 -0.8205 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O17 mock treatment 0.245 -0.0547 -0.78 0.249 -0.0372 -0.62 -0.9946 -0.9937 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O18 mock treatment 0.278 -0.0217 -0.31 0.287 8.41E-4 0.01 -0.2099 -0.6743 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O19 mock treatment 0.295 -0.00474 -0.07 0.299 0.0128 0.22 0.1045 0.4625 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O20 mock treatment 0.283 -0.0167 -0.24 0.281 -0.00516 -0.09 -0.2305 -0.9055 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O21 mock treatment 0.26 -0.0397 -0.57 0.262 -0.0242 -0.41 -0.6886 -0.9863 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O22 mock treatment 0.268 -0.0317 -0.45 0.245 -0.0412 -0.69 -0.8095 -0.9793 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O23 mock treatment 0.25 -0.0497 -0.71 0.223 -0.0632 -1.06 -1.2526 -0.9812 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base O24 mock treatment 0.218 -0.0817 -1.17 0.234 -0.0522 -0.88 -1.4457 -0.9898 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P01 mock treatment 0.289 -0.0107 -0.15 0.244 -0.0422 -0.71 -0.6089 -0.841 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P02 mock treatment 0.284 -0.0157 -0.23 0.275 -0.0112 -0.19 -0.2916 -0.9958 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P03 mock treatment 0.265 -0.0347 -0.5 0.289 0.00284 0.05 -0.3176 -0.6363 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P04 mock treatment 0.256 -0.0437 -0.63 0.286 -1.59E-4 0.0 -0.4442 -0.7101 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P05 mock treatment 0.325 0.0253 0.36 0.299 0.0128 0.22 0.4079 0.9695 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P06 mock treatment 0.296 -0.00374 -0.05 0.284 -0.00216 -0.04 -0.0634 -0.9821 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P07 mock treatment 0.299 -7.36E-4 -0.01 0.282 -0.00416 -0.07 -0.0568 -0.8047 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P08 mock treatment 0.306 0.00626 0.09 0.285 -0.00116 -0.02 0.0496 0.541 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P09 mock treatment 0.27 -0.0297 -0.43 0.248 -0.0382 -0.64 -0.7536 -0.9802 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P10 mock treatment 0.275 -0.0247 -0.35 0.277 -0.00916 -0.15 -0.3589 -0.9303 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P11 mock treatment 0.272 -0.0277 -0.4 0.257 -0.0292 -0.49 -0.6266 -0.9946 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P12 mock treatment 0.3 2.64E-4 0.0 0.268 -0.0182 -0.3 -0.2128 -0.6983 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P13 mock treatment 0.296 -0.00374 -0.05 0.298 0.0118 0.2 0.1027 0.4992 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P14 mock treatment 0.312 0.0123 0.18 0.289 0.00284 0.05 0.1578 0.8678 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P15 mock treatment 0.289 -0.0107 -0.15 0.266 -0.0202 -0.34 -0.3478 -0.9361 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P16 mock treatment 0.268 -0.0317 -0.45 0.291 0.00484 0.08 -0.2635 -0.5715 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P17 mock treatment 0.284 -0.0157 -0.23 0.28 -0.00616 -0.1 -0.2323 -0.9377 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P18 mock treatment 0.276 -0.0237 -0.34 0.256 -0.0302 -0.51 -0.598 -0.9811 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P19 mock treatment 0.284 -0.0157 -0.23 0.262 -0.0242 -0.41 -0.4459 -0.9614 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P20 mock treatment 0.266 -0.0337 -0.48 0.251 -0.0352 -0.59 -0.7585 -0.995 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P21 mock treatment 0.299 -7.36E-4 -0.01 0.298 0.0118 0.2 0.1331 0.6687 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P22 mock treatment 0.284 -0.0157 -0.23 0.268 -0.0182 -0.3 -0.3747 -0.9889 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P23 mock treatment 0.257 -0.0427 -0.61 0.24 -0.0462 -0.77 -0.9801 -0.9931 1063.0009 OpticalDensity(1063.0009) SigBInhibition 1063.0009.Base P24 mock treatment 0.224 -0.0757 -1.08 0.246 -0.0402 -0.67 -1.2426 -0.9739