ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A01 mock treatment 232591.0 -52200.0 -1.06 247407.0 -8590.0 -0.18 -0.875 -0.8151 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A02 mock treatment 233222.0 -51600.0 -1.05 256410.0 411.0 0.01 -0.7334 -0.7013 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A03 compound treatment 184558.0 -100000.0 -2.03 146880.0 -109000.0 -2.27 -3.0445 -0.9984 985 SPBio_000001 Nc1ccc(C(=O)O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A04 compound treatment 262369.0 -22400.0 -0.45 246173.0 -9830.0 -0.2 -0.4664 -0.935 1408 SPBio_000002 NC1(CC2CC3CC(C2)C1)C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A05 compound treatment 236061.0 -48700.0 -0.99 253109.0 -2890.0 -0.06 -0.7413 -0.7488 1367 SPBio_000003 Cc1cc(O)ccc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A06 compound treatment 212858.0 -71900.0 -1.46 227481.0 -28500.0 -0.59 -1.4515 -0.9216 692 SPBio_000004 CC(=O)Nc1nnc(s1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A07 compound treatment 269658.0 -15100.0 -0.31 232132.0 -23900.0 -0.5 -0.5687 -0.9732 1001324 SPBio_000005 OC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A08 compound treatment 301811.0 17000.0 0.34 317067.0 61100.0 1.27 1.1434 0.8674 2550 SPBio_000006 O[C@@H]([C@@H](COC(=O)CCC(=O)O)NC(=O)C(Cl)Cl)c1ccc(cc1)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A09 compound treatment 234307.0 -50500.0 -1.02 218263.0 -37700.0 -0.79 -1.2798 -0.9915 3058614 SPBio_000007 C[C@@H](CO)NC(=O)C1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A10 compound treatment 227394.0 -57400.0 -1.16 279366.0 23400.0 0.49 -0.4788 -0.3795 760 SPBio_000008 N[C@@H]1CONC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A11 compound treatment 247004.0 -37800.0 -0.77 257389.0 1390.0 0.03 -0.5214 -0.6799 3199904 SPBio_000009 OC(=O)c1ccccc1OC(=O)/C=C/C(=O)Oc2ccccc2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A12 compound treatment 259911.0 -24900.0 -0.5 261836.0 5840.0 0.12 -0.2709 -0.5218 1267 SPBio_000010 CC(=O)Nc1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A13 compound treatment 192637.0 -92200.0 -1.87 197932.0 -58100.0 -1.21 -2.1766 -0.9779 1300 SPBio_000011 OC(=O)c1cccnc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A14 compound treatment 240591.0 -44200.0 -0.9 238407.0 -17600.0 -0.37 -0.8929 -0.9221 1001897 SPBio_000012 CC(=O)N[C@@H](CS)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A15 compound treatment 2739.0 -282000.0 -5.72 6479.0 -250000.0 -5.2 -7.7191 -0.9989 3174099 SPBio_000013 Nc1cccc(c1)C(=C2C=CC(=N)C=C2)c3cccc(N)c3.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A16 compound treatment 235578.0 -49200.0 -1.0 261917.0 5920.0 0.12 -0.6185 -0.6151 1037 SPBio_000014 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A17 compound treatment 240130.0 -44700.0 -0.91 262178.0 6180.0 0.13 -0.5494 -0.6006 1199 SPBio_000015 CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A18 compound treatment 242639.0 -42200.0 -0.85 260799.0 4800.0 0.1 -0.5337 -0.6202 1108 SPBio_000016 Cc1cc(=O)n(c2ccccc2)n1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A19 compound treatment 250745.0 -34100.0 -0.69 246283.0 -9720.0 -0.2 -0.6314 -0.8775 1096 SPBio_000017 C[N+](C)(C)CC(O)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A20 compound treatment 268335.0 -16500.0 -0.33 233143.0 -22900.0 -0.48 -0.5728 -0.9849 1132 SPBio_000018 CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A21 compound treatment 208927.0 -75900.0 -1.54 252383.0 -3620.0 -0.08 -1.141 -0.7408 3059433 SPBio_000019 CC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A22 compound treatment 203451.0 -81400.0 -1.65 223125.0 -32900.0 -0.68 -1.6505 -0.9242 697 SPBio_000020 Cn1c(=O)n(C)c2ncn(CC(O)CO)c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A23 mock treatment 246180.0 -38600.0 -0.78 226262.0 -29700.0 -0.62 -0.9917 -0.9933 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 A24 mock treatment 211925.0 -72900.0 -1.48 203843.0 -52200.0 -1.09 -1.813 -0.9886 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B01 mock treatment 302692.0 17900.0 0.36 257339.0 1340.0 0.03 0.2762 0.7593 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B02 mock treatment 336133.0 51300.0 1.04 286302.0 30300.0 0.63 1.1822 0.9713 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B03 compound treatment 345569.0 60800.0 1.23 275448.0 19400.0 0.41 1.1576 0.8926 2060046 SPBio_000021 C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)[C@@]4(C)O[C@]43[C@H]2OC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B04 compound treatment 341084.0 56300.0 1.14 284313.0 28300.0 0.59 1.2239 0.9529 2060083 SPBio_000022 COC(=O)C(O)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B05 compound treatment 303285.0 18500.0 0.37 279543.0 23500.0 0.49 0.6118 0.9912 2060226 SPBio_000023 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c4c(=O)c(O)cc(cc34)[C@H]5Oc6cc(O)cc(O)c6C[C@H]5OC(=O)c7cc(O)c(O)c(O)c7 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B06 compound treatment 332960.0 48200.0 0.98 305158.0 49200.0 1.02 1.4145 0.9997 2060085 SPBio_000024 C[C@]12CCC3[C@@](C)([C@H](O)CC4[C@]3(C)C=CC(=O)OC4(C)C)C25OC5C(=O)O[C@H]1c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B07 compound treatment 400198.0 115000.0 2.34 284616.0 28600.0 0.6 2.0757 0.8598 2060422 SPBio_000025 CCOc1ccc(cc1)C(=O)c2cc(O)c(OC)c(OC)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B08 compound treatment 377841.0 93000.0 1.89 285094.0 29100.0 0.61 1.7623 0.8895 2069252 SPBio_000026 CCC(C)C(OC(=O)C)C(=O)O[C@H]1[C@H](OC=O)C(C(=C)C2(O)C(=O)C[C@@H](c3ccoc3)[C@]12C)[C@]4(C)C(CC(=O)OC)[C@@](C)(COC(=O)C)OC(=O)C[C@@H]4OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B09 compound treatment 366270.0 81500.0 1.65 278888.0 22900.0 0.48 1.505 0.8755 2060223 SPBio_000027 COc1cc(OC)c2C[C@H](O)[C@H](Oc2c1)c3ccc(OC)c(OC)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B10 compound treatment 397710.0 113000.0 2.29 268883.0 12900.0 0.27 1.8083 0.7847 2060087 SPBio_000028 COC(=O)C(O)[C@H]1C(C)(C)C(OC(=O)/C(=C/C)/C)[C@@H]2C=C3C(CC[C@@]4(C)[C@@H](OC(=O)CC34)c5ccoc5)[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B11 compound treatment 410994.0 126000.0 2.56 287911.0 31900.0 0.66 2.279 0.8622 2060224 SPBio_000029 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4ccc(O)c(O)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B12 compound treatment 454745.0 170000.0 3.45 277409.0 21400.0 0.45 2.7515 0.792 2060090 SPBio_000030 COC(=O)C[C@H]1C(C)(C)C(OC(=O)C)[C@]2(O)C=C3C(CC[C@@]4(C)[C@@H](OC(=O)CC34)c5ccoc5)[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B13 compound treatment 400947.0 116000.0 2.35 266584.0 10600.0 0.22 1.8208 0.77 2060169 SPBio_000031 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4c5c(O)c(O)c(O)cc5[C@H]6Oc7cc(O)cc(O)c7C[C@H]6OC(=O)c8cc(O)c(O)c(O)c8 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B14 compound treatment 385756.0 101000.0 2.05 284210.0 28200.0 0.59 1.8627 0.8748 2060089 SPBio_000032 CCC(C)C(=O)O[C@@H]1C[C@@]2(C)[C@@H](OC(=O)CC32OC4(C)O[C@]53[C@H](OC(=O)C)[C@@]6(O)C(OC(=O)C7(C)OC7C)C8(C)CC6(O)[C@@](C)([C@H]8CC(=O)OC)[C@@]15O4)c9ccoc9 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B15 compound treatment 365635.0 80800.0 1.64 279432.0 23400.0 0.49 1.5039 0.8796 1254 SPBio_000033 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B16 compound treatment 156740.0 -128000.0 -2.6 159772.0 -96200.0 -2.0 -3.2533 -0.9918 2060091 SPBio_000034 CC(CC(O)C1OC1(C)C)[C@@H]2CCC3(C)C4=CCC5C(C)(C)C(=O)CCC5(C)C4CC[C@@]23C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B17 compound treatment 274769.0 -10000.0 -0.2 274295.0 18300.0 0.38 0.1257 0.2909 1859 SPBio_000035 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B18 compound treatment 57100.0 -228000.0 -4.62 242573.0 -13400.0 -0.28 -3.4619 -0.7486 2060093 SPBio_000036 CC([C@@H]1CC[C@]2(C)C3=CCC4C(C)(C)C(=O)CC[C@]4(C)C3CC[C@@]12C)C5OC(C)(C)C(O)C5O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B19 compound treatment 355964.0 71200.0 1.44 296468.0 40500.0 0.84 1.6162 0.9673 2060218 SPBio_000037 COc1c(CC(=O)c2cc3CC(O)C(C)(C)Oc3cc2O)ccc4OC(C)(C)C=Cc14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B20 compound treatment 288626.0 3820.0 0.08 268199.0 12200.0 0.25 0.2345 0.8826 2060094 SPBio_000038 COC(=O)C(O)[C@H]1C(C)(C)[C@@H](OC(=O)C)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B21 compound treatment 327992.0 43200.0 0.88 275540.0 19500.0 0.41 0.907 0.9393 3054028 SPBio_000039 CC(CCC=C(C)C)[C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)C4(C)CC[C@H](O)C(C)(C)C4CC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B22 compound treatment 265410.0 -19400.0 -0.39 267493.0 11500.0 0.24 -0.1087 -0.2361 2060115 SPBio_000040 CC(=CCOc1cc2oc(=O)ccc2cc1O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B23 mock treatment 297384.0 12600.0 0.26 279814.0 23800.0 0.5 0.5312 0.9521 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 B24 mock treatment 251095.0 -33700.0 -0.68 253552.0 -2450.0 -0.05 -0.5193 -0.7577 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C01 mock treatment 241969.0 -42800.0 -0.87 241430.0 -14600.0 -0.3 -0.8287 -0.9008 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C02 mock treatment 237332.0 -47500.0 -0.96 267754.0 11800.0 0.24 -0.5074 -0.5109 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C03 compound treatment 62397.0 -222000.0 -4.51 25476.0 -231000.0 -4.8 -6.5841 -0.9995 2069233 SPBio_000041 COc1ccc2C3CCC4(C)C(O)[C@H](O)CC4C3CCc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C04 compound treatment 29888.0 -255000.0 -5.17 14157.0 -242000.0 -5.04 -7.2169 -0.9999 844 SPBio_000042 CNCCCN1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C05 compound treatment 251870.0 -32900.0 -0.67 130411.0 -126000.0 -2.62 -2.3222 -0.86 2069241 SPBio_000043 COc1ccc2C3CC[C@]4(C)[C@@H](O)CCC4C3CCc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C06 compound treatment 180321.0 -104000.0 -2.12 68435.0 -188000.0 -3.91 -4.2608 -0.9586 678 SPBio_000044 NCC(CC(=O)O)c1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C07 compound treatment 307150.0 22300.0 0.45 298736.0 42700.0 0.89 0.9499 0.9509 1094519 SPBio_000045 CC(=O)N1CCCC1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C08 compound treatment 301962.0 17200.0 0.35 318761.0 62800.0 1.31 1.1705 0.8651 1469 SPBio_000046 CCC1(CCC(=O)NC1=O)c2ccc(N)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C09 compound treatment 335501.0 50700.0 1.03 332902.0 76900.0 1.6 1.8596 0.977 736 SPBio_000047 COC(=O)C(N)CS 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C10 compound treatment 268285.0 -16500.0 -0.33 297817.0 41800.0 0.87 0.3792 0.4063 1000124 SPBio_000048 CN1C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C11 compound treatment 274075.0 -10700.0 -0.22 287407.0 31400.0 0.65 0.3089 0.4479 978 SPBio_000049 COC(=O)C(C)C[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C12 compound treatment 280228.0 -4580.0 -0.09 262279.0 6280.0 0.13 0.0269 0.1678 997 SPBio_000050 NCc1ccc(cc1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C13 compound treatment 255809.0 -29000.0 -0.59 243914.0 -12100.0 -0.25 -0.5937 -0.9284 2069271 SPBio_000051 C[C@H](N)[C@H](O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C14 compound treatment 260460.0 -24300.0 -0.49 263495.0 7500.0 0.16 -0.2385 -0.4608 1252 SPBio_000052 CC(C)NCC(O)c1cc(O)cc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C15 compound treatment 279442.0 -5360.0 -0.11 251760.0 -4240.0 -0.09 -0.1393 -0.9947 1404 SPBio_000053 Nc1ccc(N=Nc2ccccc2)c(N)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C16 compound treatment 85687.0 -199000.0 -4.04 31720.0 -224000.0 -4.67 -6.1582 -0.9973 1485 SPBio_000054 CCC(=C)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C17 compound treatment 280517.0 -4290.0 -0.09 262527.0 6530.0 0.14 0.0347 0.215 1090918 SPBio_000055 Cc1nc(C)c(Cl)c(O)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C18 compound treatment 251101.0 -33700.0 -0.68 287427.0 31400.0 0.65 -0.0202 -0.0213 1292 SPBio_000056 O=c1[nH]cnc2[nH]ncc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C19 compound treatment 264906.0 -19900.0 -0.4 273382.0 17400.0 0.36 -0.0292 -0.0538 3182 SPBio_000057 CCCc1cc(ccn1)C(=S)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C20 compound treatment 290895.0 6090.0 0.12 274540.0 18500.0 0.39 0.3604 0.8888 1332 SPBio_000058 NS(=O)(=O)c1cc(ccc1Cl)C2(O)NC(=O)c3ccccc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C21 compound treatment 2859.0 -282000.0 -5.72 2543.0 -253000.0 -5.28 -7.7754 -0.9992 3199905 SPBio_000059 CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c4c5nc6cc(C)ccn6c5c(NC(=O)/C(=C\C=C\[C@H](C)[C@H](O)[C@@H](C)C(O)[C@@H](C)[C@H](OC(=O)C)[C@@H]1C)/C)c(O)c4c(O)c3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C22 compound treatment 261456.0 -23300.0 -0.47 259948.0 3950.0 0.08 -0.2765 -0.5756 3177311 SPBio_000060 C[C@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C23 mock treatment 307290.0 22500.0 0.46 274015.0 18000.0 0.38 0.5877 0.9953 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 C24 mock treatment 271997.0 -12800.0 -0.26 246686.0 -9310.0 -0.19 -0.3208 -0.9897 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D01 mock treatment 313833.0 29000.0 0.59 309790.0 53800.0 1.12 1.2085 0.9548 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D02 mock treatment 302896.0 18100.0 0.37 269250.0 13300.0 0.28 0.4546 0.9902 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D03 compound treatment 245547.0 -39300.0 -0.8 220045.0 -36000.0 -0.75 -1.0924 -0.9995 2069246 SPBio_000061 Cc1cc(O)c(C=O)c2Oc3c4C(O)OC(=O)c4c(O)c(C)c3OC(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D04 compound treatment 298624.0 13800.0 0.28 302073.0 46100.0 0.96 0.8768 0.8769 2060364 SPBio_000062 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D05 compound treatment 292519.0 7710.0 0.16 258004.0 2010.0 0.04 0.1401 0.8656 3198309 SPBio_000063 CC(=O)OCC(O)CC(O)CCCCCCCCCCCC=C.CC(=O)OCC(O)CC(O)CCCCCCCCCCCC#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D06 compound treatment 365562.0 80800.0 1.64 285561.0 29600.0 0.62 1.5932 0.9108 2060372 SPBio_000064 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2CC3=C(CC[C@@]4(C)[C@@H](OC(=O)C=C34)c5ccoc5)[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D07 compound treatment 345206.0 60400.0 1.22 262468.0 6470.0 0.13 0.9612 0.7802 2060203 SPBio_000065 CCOC(=O)c1c(C)cc(O)c(C)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D08 compound treatment 347234.0 62400.0 1.27 303855.0 47900.0 1.0 1.5999 0.993 2060145 SPBio_000066 CC1(C)C2CC(=O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)[C@@]2(C)C=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D09 compound treatment 324412.0 39600.0 0.8 257745.0 1750.0 0.04 0.5935 0.7384 2060100 SPBio_000067 OC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D10 compound treatment 384171.0 99400.0 2.01 286673.0 30700.0 0.64 1.8763 0.8878 2060127 SPBio_000068 COC1CC2=C3C[C@H]4C(=O)C(C)(C)[C@H](CC(=O)OC)[C@@](C)(C3CC[C@@]2(C)[C@@H](O1)c5ccoc5)C4=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D11 compound treatment 3328.0 -281000.0 -5.71 132049.0 -124000.0 -2.58 -5.8609 -0.9357 1017609 SPBio_000069 CC(=CCc1c(O)c2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc(O)cc4)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D12 compound treatment 410471.0 126000.0 2.55 265082.0 9080.0 0.19 1.9353 0.7575 2060118 SPBio_000070 COC(=O)CC1C(C)(C)C(O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D13 compound treatment 454365.0 170000.0 3.44 202253.0 -53700.0 -1.12 1.6389 0.4533 2069330 SPBio_000071 COc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D14 compound treatment 383380.0 98600.0 2.0 258291.0 2290.0 0.05 1.4469 0.7238 2060121 SPBio_000072 COC(=O)C[C@H]1C(C)(C)C2(Cl)O[C@]34CC2C(=O)[C@]1(C)C4CC[C@@]5(C)[C@@H](OC(=O)C=C35)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D15 compound treatment 289987.0 5180.0 0.11 269628.0 13600.0 0.28 0.2751 0.9086 2060495 SPBio_000073 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3c4c(O)c(O)c(O)cc4[C@H]5Oc6cc(O)cc(O)c6C[C@H]5OC(=O)c7cc(O)c(O)c(O)c7 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D16 compound treatment 332976.0 48200.0 0.98 287926.0 31900.0 0.67 1.1609 0.9825 2060150 SPBio_000074 CC1(C)[C@H](O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]3(C)OC(=O)CC12)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D17 compound treatment 259452.0 -25400.0 -0.51 233066.0 -22900.0 -0.48 -0.7013 -0.9993 3173879 SPBio_000075 CC(=CCc1c2OC(C)(C)C=Cc2c(OC(=O)C)c3c(=O)c(OC(=O)C)c(oc13)c4ccccc4)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D18 compound treatment 303414.0 18600.0 0.38 299164.0 43200.0 0.9 0.9026 0.9256 2060154 SPBio_000076 CC(=O)O[C@H]1CC[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D19 compound treatment 280792.0 -4010.0 -0.08 250048.0 -5950.0 -0.12 -0.1452 -0.9791 3054809 SPBio_000077 COc1ccc2C(=O)C(Cc3ccc(OC)c(OC(=O)C)c3)COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D20 compound treatment 326574.0 41800.0 0.85 241978.0 -14000.0 -0.29 0.3922 0.4379 2060037 SPBio_000078 CC(=O)O[C@@H]1CC[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D21 compound treatment 296144.0 11300.0 0.23 234855.0 -21100.0 -0.44 -0.1489 -0.2997 2060139 SPBio_000079 COc1ccc([C@@H]2COc3c(OC)c(OC)ccc3C2)c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D22 compound treatment 274653.0 -10200.0 -0.21 229360.0 -26600.0 -0.55 -0.5379 -0.9088 2060350 SPBio_000080 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D23 mock treatment 296799.0 12000.0 0.24 232276.0 -23700.0 -0.49 -0.1775 -0.3223 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 D24 mock treatment 269820.0 -15000.0 -0.3 227828.0 -28200.0 -0.59 -0.6298 -0.953 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E01 mock treatment 267580.0 -17200.0 -0.35 256435.0 436.0 0.01 -0.2405 -0.6885 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E02 mock treatment 250335.0 -34500.0 -0.7 244154.0 -11800.0 -0.25 -0.6686 -0.9022 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E03 compound treatment 266224.0 -18600.0 -0.38 243700.0 -12300.0 -0.26 -0.4475 -0.9824 1014792 SPBio_000081 OC(=O)c1cc2ccccc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E04 compound treatment 268093.0 -16700.0 -0.34 234198.0 -21800.0 -0.45 -0.5607 -0.9896 1365 SPBio_000082 CN(C)CCC=C1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E05 compound treatment 49172.0 -236000.0 -4.78 54688.0 -201000.0 -4.19 -6.3433 -0.9979 3173210 SPBio_000083 CO/N=C(\C(=O)NC1[C@H]2SCC(=C(N2C1=O)C(=O)O)CSc3nc(=O)c(=O)[nH]n3C)/c4csc(N)n4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E06 compound treatment 260164.0 -24600.0 -0.5 254998.0 -1000.0 -0.02 -0.368 -0.736 3173722 SPBio_000084 NCC[C@@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)C3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E07 compound treatment 217396.0 -67400.0 -1.37 203430.0 -52600.0 -1.1 -1.7407 -0.994 1310 SPBio_000085 NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@H]([C@H](OP(=O)(O)O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E08 compound treatment 2401.0 -282000.0 -5.73 2198.0 -254000.0 -5.29 -7.787 -0.9992 712 SPBio_000086 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSc3ccncc3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E09 compound treatment 140303.0 -145000.0 -2.93 31974.0 -224000.0 -4.67 -5.3716 -0.9748 1010201 SPBio_000087 ClC1=C(Cl)C(=O)C(=C(Cl)C1=O)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E10 compound treatment 282171.0 -2630.0 -0.05 290150.0 34200.0 0.71 0.4653 0.6522 679 SPBio_000088 CC(=O)Nc1cc(ccc1O)[As](=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E11 compound treatment 286685.0 1880.0 0.04 224845.0 -31200.0 -0.65 -0.432 -0.6644 193 SPBio_000089 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E12 compound treatment 3487.0 -281000.0 -5.7 2271.0 -254000.0 -5.29 -7.7704 -0.9993 995 SPBio_000090 CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@@H]([C@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E13 compound treatment 4314.0 -280000.0 -5.69 2240.0 -254000.0 -5.29 -7.759 -0.9993 2801 SPBio_000091 CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E14 compound treatment 240189.0 -44600.0 -0.9 253726.0 -2270.0 -0.05 -0.673 -0.7431 1141 SPBio_000092 CN1C2CCC1CC(C2)OC(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E15 compound treatment 2533.0 -282000.0 -5.72 2098.0 -254000.0 -5.29 -7.7866 -0.9992 3199906 SPBio_000093 CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(=C/[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC)/C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E16 compound treatment 213783.0 -71000.0 -1.44 194573.0 -61400.0 -1.28 -1.923 -0.9983 735 SPBio_000094 NNC(=O)c1ccncc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E17 compound treatment 280537.0 -4270.0 -0.09 236526.0 -19500.0 -0.41 -0.348 -0.839 2069298 SPBio_000095 CC(=O)Nc1c(I)cc(I)c(C(=O)O)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E18 compound treatment 257270.0 -27500.0 -0.56 281703.0 25700.0 0.54 -0.0161 -0.0208 1519 SPBio_000096 CC1(C)OC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E19 compound treatment 255563.0 -29200.0 -0.59 244886.0 -11100.0 -0.23 -0.5829 -0.9159 3173493 SPBio_000097 CC1=C2CCC3C4CCC(=O)[C@@]4(C)CCC3[C@@]2(C)CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E20 compound treatment 274076.0 -10700.0 -0.22 269146.0 13100.0 0.27 0.0399 0.114 1414 SPBio_000098 CC(=O)NO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E21 compound treatment 297697.0 12900.0 0.26 232445.0 -23600.0 -0.49 -0.1622 -0.2917 1467 SPBio_000099 CCCCOc1ccc(OCCCN2CCOCC2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E22 compound treatment 224661.0 -60100.0 -1.22 190196.0 -65800.0 -1.37 -1.8315 -0.9983 1035 SPBio_000100 Cc1cccc(CN2CCN(CC2)C(c3ccccc3)c4ccc(Cl)cc4)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E23 mock treatment 316566.0 31800.0 0.64 221040.0 -35000.0 -0.73 -0.0597 -0.0614 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 E24 mock treatment 286362.0 1560.0 0.03 207586.0 -48400.0 -1.01 -0.6908 -0.6846 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F01 mock treatment 293899.0 9090.0 0.18 244717.0 -11300.0 -0.24 -0.0358 -0.1199 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F02 mock treatment 342443.0 57600.0 1.17 260585.0 4590.0 0.1 0.8938 0.7624 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F03 compound treatment 281649.0 -3160.0 -0.06 213294.0 -42700.0 -0.89 -0.6743 -0.756 3173749 SPBio_000101 COc1cc2OC[C@H]3Oc4c5CC(Oc5ccc4C(=O)[C@H]3c2cc1OC)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F04 compound treatment 157702.0 -127000.0 -2.58 160761.0 -95200.0 -1.98 -3.225 -0.9917 2060160 SPBio_000102 CC(=O)O[C@@H]1CC2C(C)(C)CCC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F05 compound treatment 409027.0 124000.0 2.52 298414.0 42400.0 0.88 2.4056 0.9013 1008719 SPBio_000103 COC(=O)C(O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F06 compound treatment 433324.0 149000.0 3.01 294843.0 38800.0 0.81 2.7013 0.8664 2060129 SPBio_000104 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F07 compound treatment 391521.0 107000.0 2.16 291259.0 35300.0 0.73 2.0492 0.8969 2060163 SPBio_000105 COc1ccc2C(=O)[C@@H]3[C@@H](COc4cc(OC)c(OC)cc34)Oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F08 compound treatment 384333.0 99500.0 2.02 251193.0 -4810.0 -0.1 1.356 0.6712 2060365 SPBio_000106 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)C3OC3[C@]2(C)C4CC[C@@]5(C)[C@@H](OC(=O)C6OC65[C@]14C)c7ccoc7 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F09 compound treatment 412592.0 128000.0 2.59 321053.0 65100.0 1.36 2.7902 0.9543 2060165 SPBio_000107 COc1cc2OCc3oc4c5CC(Oc5ccc4c(=O)c3-c2cc1OC)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F10 compound treatment 410338.0 126000.0 2.54 223853.0 -32100.0 -0.67 1.326 0.5039 2060162 SPBio_000108 COC(=O)C[C@H]1C(C)(C)[C@@H](O)[C@@H]2CC3=C4C=C(OC)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F11 compound treatment 422541.0 138000.0 2.79 229209.0 -26800.0 -0.56 1.5798 0.5548 1372522 SPBio_000109 COc1ccc(cc1)c2coc3cc(OC)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F12 compound treatment 382466.0 97700.0 1.98 218912.0 -37100.0 -0.77 0.8537 0.4017 2060177 SPBio_000110 CC1(C)C2C[C@@H](O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)[C@@]2(C)[C@H]7O[C@H]7C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F13 compound treatment 335314.0 50500.0 1.02 226974.0 -29000.0 -0.6 0.2965 0.2493 2069309 SPBio_000111 COc1cc2OC[C@H]3Oc4c5CCC(C)(C)Oc5ccc4C(=O)[C@H]3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F14 compound treatment 412763.0 128000.0 2.59 272698.0 16700.0 0.35 2.0803 0.7948 2060320 SPBio_000112 COc1ccc2CC[C@@H]3CC(=O)CC[C@]3(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F15 compound treatment 428055.0 143000.0 2.9 230902.0 -25100.0 -0.52 1.6838 0.5706 2060494 SPBio_000113 COc1ccc2C(=O)C(Cc3ccc(OC)c(OC)c3)COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F16 compound treatment 285437.0 633.0 0.01 158392.0 -97600.0 -2.03 -1.4288 -0.7026 3173369 SPBio_000114 CC(C)c1c(OC(=O)C)ccc2c1CCC3C(C)(C)CCC[C@@]32C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F17 compound treatment 334164.0 49400.0 1.0 258539.0 2540.0 0.05 0.745 0.7435 2060110 SPBio_000115 COc1ccc(c(OC)c1)c2coc3cc(O)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F18 compound treatment 3149.0 -282000.0 -5.71 2341.0 -254000.0 -5.28 -7.7742 -0.9993 2060034 SPBio_000116 CC(C)c1c(O)ccc2c1CCC3[C@](C)(CCC[C@@]32C)C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F19 compound treatment 302629.0 17800.0 0.36 272637.0 16600.0 0.35 0.5006 0.9998 2060102 SPBio_000117 COc1ccc2C(=O)c3cc(OC)c(OC)cc3CC(=O)COc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F20 compound treatment 175139.0 -110000.0 -2.22 124862.0 -131000.0 -2.73 -3.5039 -0.9948 2060126 SPBio_000118 CC(C)c1c(O)ccc2c1CCC3[C@@](C)(CO)CCC[C@@]32C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F21 compound treatment 277566.0 -7240.0 -0.15 257984.0 1990.0 0.04 -0.0745 -0.4888 1059133 SPBio_000119 COc1ccc(C(=O)c2ccccc2)c(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F22 compound treatment 275692.0 -9110.0 -0.18 187829.0 -68200.0 -1.42 -1.1348 -0.7924 3053987 SPBio_000120 CC(=O)C1CC[C@H]2C3CC[C@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F23 mock treatment 294180.0 9380.0 0.19 233255.0 -22700.0 -0.47 -0.2006 -0.393 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 F24 mock treatment 273567.0 -11200.0 -0.23 262788.0 6790.0 0.14 -0.0611 -0.2278 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G01 mock treatment 254191.0 -30600.0 -0.62 237923.0 -18100.0 -0.38 -0.7051 -0.9713 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G02 mock treatment 267121.0 -17700.0 -0.36 269608.0 13600.0 0.28 -0.053 -0.116 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G03 compound treatment 285290.0 486.0 0.01 265400.0 9400.0 0.2 0.1455 0.7417 2060144 SPBio_000121 COc1cccc(c1)c2cc(=O)c3cc(OC)ccc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G04 compound treatment 221122.0 -63700.0 -1.29 230066.0 -25900.0 -0.54 -1.2949 -0.9253 696 SPBio_000122 Oc1cccc2Cc3cccc(O)c3C(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G05 compound treatment 283835.0 -969.0 -0.02 271865.0 15900.0 0.33 0.2198 0.6639 3077146 SPBio_000123 CN[C@@H]1[C@@H](O)C(OC2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](C(C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@H]2O)OC[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G06 compound treatment 266994.0 -17800.0 -0.36 257082.0 1080.0 0.02 -0.2394 -0.6616 1124 SPBio_000124 CN1C2CC[C@@H]1C[C@H](C2)OC(=O)[C@H](CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G07 compound treatment 280714.0 -4090.0 -0.08 274481.0 18500.0 0.39 0.2136 0.5424 3077147 SPBio_000125 CC(O)Cn1c(C)ncc1[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G08 compound treatment 2690.0 -282000.0 -5.72 2664.0 -253000.0 -5.28 -7.776 -0.9992 1247 SPBio_000126 Oc1c(Cl)cc(Cl)cc1Sc2cc(Cl)cc(Cl)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G09 compound treatment 32506.0 -252000.0 -5.11 27331.0 -229000.0 -4.76 -6.9853 -0.9994 1461079 SPBio_000127 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCN(C)CC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G10 compound treatment 260290.0 -24500.0 -0.5 282304.0 26300.0 0.55 0.0361 0.0488 1327 SPBio_000128 C[N+](C)(C)CCOC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G11 compound treatment 39404.0 -245000.0 -4.97 14195.0 -242000.0 -5.04 -7.0799 -1.0 3480340 SPBio_000129 c1cn(cn1)C(c2ccccc2)c3ccc(cc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G12 compound treatment 275311.0 -9490.0 -0.19 297494.0 41500.0 0.86 0.4752 0.5365 1432 SPBio_000130 CN(C)CCOC(C)(c1ccccc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G13 compound treatment 6055.0 -279000.0 -5.65 6018.0 -250000.0 -5.21 -7.6784 -0.9992 3199907 SPBio_000131 OC(=O)c1cn(c2ccc(F)cc2)c3cc(N4CCNCC4)c(F)cc3c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G14 compound treatment 286641.0 1840.0 0.04 277718.0 21700.0 0.45 0.3463 0.7627 873 SPBio_000132 Nc1nc(=O)c2N(C=O)C(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)CNc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G15 compound treatment 192096.0 -92700.0 -1.88 96752.0 -159000.0 -3.32 -3.6749 -0.9638 1007083 SPBio_000133 Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G16 compound treatment 268089.0 -16700.0 -0.34 278792.0 22800.0 0.47 0.0962 0.1648 1513 SPBio_000134 CCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G17 compound treatment 138128.0 -147000.0 -2.97 86839.0 -169000.0 -3.52 -4.5945 -0.9964 1008492 SPBio_000135 O=C(CC(=O)c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G18 compound treatment 280346.0 -4460.0 -0.09 229707.0 -26300.0 -0.55 -0.4512 -0.8128 1000042 SPBio_000136 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G19 compound treatment 262177.0 -22600.0 -0.46 248619.0 -7380.0 -0.15 -0.4331 -0.8952 3480338 SPBio_000137 OC(=O)C(Cc1cc(=O)[nH]c2ccccc12)NC(=O)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G20 compound treatment 2682.0 -282000.0 -5.72 2515.0 -253000.0 -5.28 -7.7784 -0.9992 3172713 SPBio_000138 CO/N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC(=O)C)\c3csc(N)n3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G21 compound treatment 246577.0 -38200.0 -0.77 231708.0 -24300.0 -0.51 -0.9058 -0.9787 903 SPBio_000139 COC(=O)Nc1nc2ccc(Sc3ccccc3)cc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G22 compound treatment 273403.0 -11400.0 -0.23 249946.0 -6050.0 -0.13 -0.2526 -0.9594 1336 SPBio_000140 CC1(C)S[C@@H]2[C@H](NC(=O)C(C(=O)O)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G23 mock treatment 280487.0 -4320.0 -0.09 264046.0 8050.0 0.17 0.0567 0.2996 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 G24 mock treatment 296650.0 11800.0 0.24 266414.0 10400.0 0.22 0.3232 0.9987 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H01 mock treatment 304290.0 19500.0 0.4 313686.0 57700.0 1.2 1.1291 0.8926 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H02 mock treatment 345480.0 60700.0 1.23 285746.0 29700.0 0.62 1.308 0.9496 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H03 compound treatment 420555.0 136000.0 2.75 311717.0 55700.0 1.16 2.7668 0.9263 2060106 SPBio_000141 COc1cc(cc(OC)c1OC)c2coc3cc(OC)c(OC)c(OC)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H04 compound treatment 3121.0 -282000.0 -5.71 3047.0 -253000.0 -5.27 -7.7642 -0.9992 3173992 SPBio_000142 CC(C)c1c(O)ccc2c1CCC3C(C)(C)CCC[C@@]32C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H05 compound treatment 364519.0 79700.0 1.62 296083.0 40100.0 0.84 1.7332 0.9528 3054981 SPBio_000143 COc1ccc(cc1)c2cc(=O)c3c(OC(=O)C)cc(OC(=O)C)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H06 compound treatment 404212.0 119000.0 2.42 246966.0 -9030.0 -0.19 1.5787 0.6502 2060280 SPBio_000144 C[C@H]1C2C(CC3C4CC[C@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)OC(=O)C)O[C@]61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H07 compound treatment 403703.0 119000.0 2.41 197801.0 -58200.0 -1.21 0.8471 0.314 3054030 SPBio_000145 Oc1cc(O)cc(/C=C/c2ccccc2)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H08 compound treatment 404625.0 120000.0 2.43 298243.0 42200.0 0.88 2.3399 0.9057 3174366 SPBio_000146 C[C@H]1C2C(CC3C4CC[C@@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)OC(=O)C)O[C@]61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H09 compound treatment 398481.0 114000.0 2.3 224773.0 -31200.0 -0.65 1.1696 0.4884 3055207 SPBio_000147 COc1cc(O)cc(/C=C/c2ccccc2)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H10 compound treatment 415173.0 130000.0 2.64 282388.0 26400.0 0.55 2.2576 0.8363 2060351 SPBio_000148 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@H](CC[C@]5(C)C4=CC(=O)[C@]23C)OC(=O)C)OC61OCC(C)CC6Br 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H11 compound treatment 388657.0 104000.0 2.11 172147.0 -83900.0 -1.75 0.2535 0.0927 3054032 SPBio_000149 COc1cc(C/C=C/c2ccccc2)c(OC)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H12 compound treatment 364861.0 80100.0 1.62 278442.0 22400.0 0.47 1.4782 0.8752 2060188 SPBio_000150 C[C@H]1C2C(CC3C4CCC5C[C@@H](O)CCC5(C)C4=CCC23C)OC61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H13 compound treatment 373037.0 88200.0 1.79 274596.0 18600.0 0.39 1.5388 0.8408 2060259 SPBio_000151 COc1ccc2c(=O)c(CC(=O)O)coc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H14 compound treatment 348304.0 63500.0 1.29 220005.0 -36000.0 -0.75 0.38 0.2551 3173999 SPBio_000152 C[C@H]1C2C(CC3C4CC[C@H]5CC(CCC5(C)C4CC(=O)C23C)OC(=O)C)OC61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H15 compound treatment 393923.0 109000.0 2.21 230271.0 -25700.0 -0.54 1.1852 0.5207 2060294 SPBio_000153 COc1ccc2C(=O)C(Cc3ccc(OC)c(O)c3)COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H16 compound treatment 362817.0 78000.0 1.58 271317.0 15300.0 0.32 1.344 0.833 3054097 SPBio_000154 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CC[C@@H](C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H17 compound treatment 323191.0 38400.0 0.78 251816.0 -4180.0 -0.09 0.4887 0.624 2060133 SPBio_000155 COc1cc(cc(O)c1OC)c2coc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c(O)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H18 compound treatment 353135.0 68300.0 1.39 227468.0 -28500.0 -0.59 0.5592 0.371 3173995 SPBio_000156 C[C@H]1C2C(O[C@@]31CC[C@@H](C)CO3)C(O)C4C5CC[C@H]6C[C@H](O[C@@H]7O[C@H](CO)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O[C@@H]%10O[C@H](CO)[C@H](O)[C@H](O[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)[C@H]%10O)[C@H](O)[C@H]7O)[C@H](O)C[C@]6(C)C5CC[C@]24C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H19 compound treatment 361226.0 76400.0 1.55 269190.0 13200.0 0.27 1.2898 0.8197 3054129 SPBio_000157 CO[C@@H]1CC2N3CC(O)C2(C=C1)c4cc5OCOc5c(OC)c4C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H20 compound treatment 275055.0 -9750.0 -0.2 238222.0 -17800.0 -0.37 -0.4016 -0.9568 1355 SPBio_000158 CC(C)(O)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H21 compound treatment 217332.0 -67500.0 -1.37 146962.0 -109000.0 -2.27 -2.5735 -0.9705 2060069 SPBio_000159 COc1cc(cc(O)c1OC)c2coc3cc(OCc4ccccc4)c(OC)c(O)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H22 compound treatment 260755.0 -24000.0 -0.49 246541.0 -9460.0 -0.2 -0.4841 -0.9205 2060207 SPBio_000160 CC1(C)[C@H](O)C[C@H](O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H23 mock treatment 270148.0 -14700.0 -0.3 239486.0 -16500.0 -0.34 -0.4534 -0.9973 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 H24 mock treatment 345305.0 60500.0 1.23 254267.0 -1730.0 -0.04 0.8418 0.686 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I01 mock treatment 252398.0 -32400.0 -0.66 272681.0 16700.0 0.35 -0.2188 -0.2944 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I02 mock treatment 296598.0 11800.0 0.24 266870.0 10900.0 0.23 0.3292 0.9996 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I03 compound treatment 245186.0 -39600.0 -0.8 215347.0 -40700.0 -0.85 -1.1668 -0.9996 2060260 SPBio_000161 COc1ccc(cc1)C2CC(=O)c3ccc(OC)cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I04 compound treatment 2556.0 -282000.0 -5.72 2184.0 -254000.0 -5.29 -7.785 -0.9992 759 SPBio_000162 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I05 compound treatment 305447.0 20600.0 0.42 295238.0 39200.0 0.82 0.874 0.9516 2335 SPBio_000163 COc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I06 compound treatment 303432.0 18600.0 0.38 272234.0 16200.0 0.34 0.5062 0.9985 807 SPBio_000164 CCCc1ncc(C[n+]2ccccc2C)c(N)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I07 compound treatment 247800.0 -37000.0 -0.75 241068.0 -14900.0 -0.31 -0.7504 -0.924 1025940 SPBio_000165 Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I08 compound treatment 270172.0 -14600.0 -0.3 261841.0 5840.0 0.12 -0.1237 -0.3858 1381 SPBio_000166 Nc1ccc(cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I09 compound treatment 271594.0 -13200.0 -0.27 279567.0 23600.0 0.49 0.1578 0.2822 2516 SPBio_000167 CC(C)OC(=O)Nc1cccc(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I10 compound treatment 310801.0 26000.0 0.53 289197.0 33200.0 0.69 0.8617 0.991 1303 SPBio_000168 C[N+]1(CCC2CC1)CC2OC(=O)C(O)(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I11 compound treatment 277027.0 -7780.0 -0.16 278252.0 22300.0 0.46 0.2163 0.4418 2069315 SPBio_000169 COc1cc(OC)c2c(=O)c(coc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I12 compound treatment 300044.0 15200.0 0.31 249371.0 -6630.0 -0.14 0.1208 0.3571 1019 SPBio_000170 NC(=O)N1c2ccccc2C=Cc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I13 compound treatment 204603.0 -80200.0 -1.63 192433.0 -63600.0 -1.32 -2.0861 -0.9948 2060112 SPBio_000171 COc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I14 compound treatment 267859.0 -16900.0 -0.34 268981.0 13000.0 0.27 -0.0517 -0.1182 1400 SPBio_000172 CC(C)[C@@H](C)/C=C/[C@@H](C)C1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)CCC3=C)\CCC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I15 compound treatment 241014.0 -43800.0 -0.89 202926.0 -53100.0 -1.11 -1.4096 -0.9941 1602 SPBio_000173 COc1ccc(cc1)c2coc3cc(O)cc(O)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I16 compound treatment 281149.0 -3660.0 -0.07 293551.0 37600.0 0.78 0.5008 0.6373 1000114 SPBio_000174 CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I17 compound treatment 176367.0 -108000.0 -2.2 158428.0 -97600.0 -2.03 -2.9918 -0.9992 2069308 SPBio_000175 CC(=CCc1c(O)cc2occ(c3ccc4OCOc4c3)c(=O)c2c1O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I18 compound treatment 14211.0 -271000.0 -5.49 11342.0 -245000.0 -5.1 -7.483 -0.9993 1272 SPBio_000176 Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I19 compound treatment 249985.0 -34800.0 -0.71 254969.0 -1030.0 -0.02 -0.5143 -0.7283 1534 SPBio_000177 O=C(/C=C/C=C/c1ccc2OCOc2c1)N3CCCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I20 compound treatment 276292.0 -8510.0 -0.17 233058.0 -22900.0 -0.48 -0.46 -0.9052 1000138 SPBio_000178 CC(C)Cc1ccc(cc1)C(C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I21 compound treatment 259260.0 -25500.0 -0.52 216372.0 -39600.0 -0.83 -0.9499 -0.9748 2060354 SPBio_000179 COc1ccc(cc1)c2coc3cc(OC(=O)C)cc(OC(=O)C)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I22 compound treatment 239386.0 -45400.0 -0.92 192345.0 -63700.0 -1.33 -1.5888 -0.9841 1157 SPBio_000180 CC(=O)N1CCN(CC1)c2ccc(OCC3CO[C@@](Cn4ccnc4)(O3)c5ccc(Cl)cc5Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I23 mock treatment 271872.0 -12900.0 -0.26 251356.0 -4640.0 -0.1 -0.2538 -0.9081 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 I24 mock treatment 267704.0 -17100.0 -0.35 231959.0 -24000.0 -0.5 -0.5993 -0.9839 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J01 mock treatment 318622.0 33800.0 0.69 291804.0 35800.0 0.75 1.0122 0.9991 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J02 mock treatment 471637.0 187000.0 3.79 276016.0 20000.0 0.42 2.9731 0.7802 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J03 compound treatment 390268.0 105000.0 2.14 287424.0 31400.0 0.65 1.9748 0.8832 2120750 SPBio_000181 CC(C)C(C)/C=C/C(C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J04 compound treatment 424408.0 140000.0 2.83 317966.0 62000.0 1.29 2.9141 0.9368 2060212 SPBio_000182 CC1(C)[C@H](O)CC(=O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J05 compound treatment 390157.0 105000.0 2.14 315515.0 59500.0 1.24 2.387 0.9665 2060070 SPBio_000183 COc1c(O)cc(O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J06 compound treatment 412956.0 128000.0 2.6 296472.0 40500.0 0.84 2.4333 0.8909 3054128 SPBio_000184 COC1C[C@H]2N3CC(O)C2(C=C1)c4cc5OCOc5cc4C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J07 compound treatment 349677.0 64900.0 1.32 255650.0 -349.0 -0.01 0.9248 0.7032 3177381 SPBio_000185 Oc1ccc(cc1)C(=O)/C=C/c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J08 compound treatment 436441.0 152000.0 3.07 286879.0 30900.0 0.64 2.6286 0.837 2060036 SPBio_000186 CC1=CCc2c(O)c3c(=O)cc(C)oc3cc2OC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J09 compound treatment 442163.0 157000.0 3.19 298026.0 42000.0 0.88 2.8749 0.869 2060263 SPBio_000187 COc1ccc(C(=O)c2ccc(O)cc2)c(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J10 compound treatment 454295.0 169000.0 3.44 283668.0 27700.0 0.58 2.8373 0.8144 2060187 SPBio_000188 COc1cccc(/C=C/C(=O)O)c1C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J11 compound treatment 428567.0 144000.0 2.91 272124.0 16100.0 0.34 2.2984 0.7834 1032994 SPBio_000189 O=C1CC(Oc2ccccc12)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J12 compound treatment 454048.0 169000.0 3.43 255697.0 -302.0 -0.01 2.4217 0.7058 2060117 SPBio_000190 Cc1ccc2c(CC[C@H]3CC(=O)CC[C@@]32C)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J13 compound treatment 423948.0 139000.0 2.82 244230.0 -11800.0 -0.25 1.8213 0.6432 2060208 SPBio_000191 COC(=O)C[C@H]1C(C)(C)[C@@H](O)[C@@H]2CC3=C4CC(O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J14 compound treatment 435881.0 151000.0 3.06 258245.0 2250.0 0.05 2.1988 0.7178 2060158 SPBio_000192 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](OC(=O)C)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J15 compound treatment 381058.0 96300.0 1.95 285036.0 29000.0 0.6 1.8076 0.8848 3058620 SPBio_000193 O[C@@H](C(=O)O)[C@@](O)(Cc1ccc(O)cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J16 compound treatment 348180.0 63400.0 1.28 255835.0 -164.0 0.0 0.9061 0.7052 2060153 SPBio_000194 COc1cccc2c1CCC3=CC(=O)CC[C@@]32C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J17 compound treatment 379331.0 94500.0 1.92 224258.0 -31700.0 -0.66 0.8875 0.4378 2060238 SPBio_000195 Cc1cc(O)cc(O)c1C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)O)c(O)c3)c(O)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J18 compound treatment 300963.0 16200.0 0.33 276043.0 20000.0 0.42 0.5269 0.9928 3173991 SPBio_000196 C[C@@]12CCC3C(CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)C[C@H](O)[C@@H]1C5=CC(=O)OC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J19 compound treatment 226953.0 -57900.0 -1.17 214143.0 -41900.0 -0.87 -1.4459 -0.9893 2060216 SPBio_000197 COc1cc2OC[C@H]3Oc4c(ccc5oc(cc45)C(C)C)C(=O)[C@H]3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J20 compound treatment 267008.0 -17800.0 -0.36 210298.0 -45700.0 -0.95 -0.9283 -0.9118 2060214 SPBio_000198 COc1c(ccc2OC(C)(C)C=Cc12)c3coc4cc5OC(C)(C)C(O)Cc5cc4c3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J21 compound treatment 316923.0 32100.0 0.65 251195.0 -4800.0 -0.1 0.3897 0.5915 2060242 SPBio_000199 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O[C@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J22 compound treatment 280819.0 -3990.0 -0.08 237948.0 -18100.0 -0.38 -0.323 -0.8399 3077173 SPBio_000200 CCOc1ccc(cc1)C(=O)c2ccc(OC)c(O)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J23 mock treatment 290289.0 5480.0 0.11 244177.0 -11800.0 -0.25 -0.0955 -0.3535 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 J24 mock treatment 285023.0 219.0 0.0 292322.0 36300.0 0.76 0.5382 0.7112 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K01 mock treatment 278049.0 -6760.0 -0.14 260492.0 4490.0 0.09 -0.0306 -0.1847 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K02 mock treatment 303198.0 18400.0 0.37 278965.0 23000.0 0.48 0.602 0.9924 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K03 compound treatment 310141.0 25300.0 0.51 257385.0 1390.0 0.03 0.3836 0.7457 1403 SPBio_000201 COC(=O)C1=CCCN(C)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K04 compound treatment 289059.0 4250.0 0.09 312642.0 56600.0 1.18 0.8954 0.7568 1167 SPBio_000202 NCCCCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K05 compound treatment 319100.0 34300.0 0.7 299237.0 43200.0 0.9 1.1286 0.9918 1013706 SPBio_000203 O=c1c2ccccc2oc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K06 compound treatment 294785.0 9980.0 0.2 276513.0 20500.0 0.43 0.4453 0.9417 834 SPBio_000204 CC(C[N+](C)(C)C)OC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K07 compound treatment 278671.0 -6130.0 -0.12 304397.0 48400.0 1.01 0.625 0.6152 592 SPBio_000205 Oc1ccc(cc1)c2coc3cc(O)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K08 compound treatment 277910.0 -6890.0 -0.14 289932.0 33900.0 0.71 0.401 0.5565 1059 SPBio_000206 CN(C)CC/C=C\1/c2ccccc2COc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K09 compound treatment 145219.0 -140000.0 -2.83 152826.0 -103000.0 -2.15 -3.5208 -0.9908 2069329 SPBio_000207 COc1cc(O)c2c(=O)cc(oc2c1)c3ccc(OC)c(c3)c4c(O)cc(O)c5c(=O)cc(oc45)c6ccc(O)cc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K10 compound treatment 2327.0 -282000.0 -5.73 2762.0 -253000.0 -5.28 -7.7798 -0.9992 1373 SPBio_000208 CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K11 compound treatment 243138.0 -41700.0 -0.84 271669.0 15700.0 0.33 -0.3665 -0.4047 2069249 SPBio_000209 COc1ccc(cc1)c2coc3c(O)c(OC)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K12 compound treatment 87782.0 -197000.0 -3.99 11765.0 -244000.0 -5.09 -6.4222 -0.9928 1360 SPBio_000210 Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K13 compound treatment 258458.0 -26300.0 -0.53 227085.0 -28900.0 -0.6 -0.8036 -0.9982 1250 SPBio_000211 COc1cc(C)c2c(=O)cc(oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K14 compound treatment 259392.0 -25400.0 -0.52 272108.0 16100.0 0.34 -0.127 -0.2065 1396 SPBio_000212 Cc1cc(O)cc(C)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K15 compound treatment 270725.0 -14100.0 -0.29 233591.0 -22400.0 -0.47 -0.5319 -0.9721 1672652 SPBio_000213 COc1ccc(cc1)c2cc(=O)c3ccc(OC)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K16 compound treatment 294896.0 10100.0 0.2 267649.0 11700.0 0.24 0.3163 0.9964 2069266 SPBio_000214 CNC(C)[C@H](O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K17 compound treatment 184412.0 -100000.0 -2.04 159902.0 -96100.0 -2.0 -2.8547 -1.0 2069226 SPBio_000215 COc1ccc2-c3oc4cc(OC)ccc4c3COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K18 compound treatment 279652.0 -5150.0 -0.1 286305.0 30300.0 0.63 0.3726 0.5822 1445 SPBio_000216 C/C=C(/C)\C(=O)O[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@H]4[C@@]2(C[C@@]5(O)[C@@H]6CN7C[C@@H](C)CC[C@H]7[C@@](C)(O)[C@@]6(O)[C@@H](O)C[C@@]45O)O[C@@]31O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K19 compound treatment 271110.0 -13700.0 -0.28 270263.0 14300.0 0.3 0.0138 0.034 353 SPBio_000217 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K20 compound treatment 244975.0 -39800.0 -0.81 247301.0 -8700.0 -0.18 -0.6991 -0.8448 1476 SPBio_000218 CNCCCC1(CCC2c3ccccc31)c4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K21 compound treatment 182819.0 -102000.0 -2.07 162339.0 -93700.0 -1.95 -2.8417 -0.9996 1116 SPBio_000219 S=c1[nH]cnc2nc[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K22 compound treatment 266107.0 -18700.0 -0.38 252442.0 -3560.0 -0.07 -0.3204 -0.8296 1095 SPBio_000220 NC(CO)C(=O)NNCc1ccc(O)c(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K23 mock treatment 326305.0 41500.0 0.84 245195.0 -10800.0 -0.23 0.4358 0.5003 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 K24 mock treatment 280255.0 -4550.0 -0.09 241958.0 -14000.0 -0.29 -0.2721 -0.887 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L01 mock treatment 341980.0 57200.0 1.16 251965.0 -4030.0 -0.08 0.7602 0.6541 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L02 mock treatment 445029.0 160000.0 3.25 312695.0 56700.0 1.18 3.132 0.9062 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L03 compound treatment 406676.0 122000.0 2.47 290725.0 34700.0 0.72 2.2586 0.8773 1090422 SPBio_000221 Cc1cc(O)cc(O)c1C(=O)Oc2cc(C)c(C(=O)O)c(O)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L04 compound treatment 343773.0 59000.0 1.2 278960.0 23000.0 0.48 1.1836 0.9192 3077174 SPBio_000222 CC(=O)Oc1ccc(cc1)c2cc(=O)c3c(OC(=O)C)cc(OC(=O)C)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L05 compound treatment 441291.0 156000.0 3.17 310850.0 54900.0 1.14 3.0513 0.9049 2060043 SPBio_000223 COc1cc(OC)c(Cl)c2OC3(C(C)CC(=O)C=C3O)C(=O)c21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L06 compound treatment 461568.0 177000.0 3.58 298391.0 42400.0 0.88 3.1584 0.8558 3077175 SPBio_000224 COc1ccc2C(=O)/C(=C\c3ccc(O)c(O)c3)/COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L07 compound treatment 361357.0 76600.0 1.55 306614.0 50600.0 1.05 1.843 0.9823 812 SPBio_000225 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3c(C2=O)c(OC)cc(OC)c3Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L08 compound treatment 464153.0 179000.0 3.64 272629.0 16600.0 0.35 2.816 0.771 3054572 SPBio_000226 CC(=O)O[C@@H]1CC[C@@]2(C)C(CC[C@]3(C)C2CC=C4C5CC(C)(C)CC[C@@]5(CC[C@]43C)C(=O)O)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L09 compound treatment 388761.0 104000.0 2.11 257016.0 1020.0 0.02 1.5052 0.7142 1051460 SPBio_000227 COc1cc(C(=O)O)c2Oc3c(C=O)c(O)cc(C)c3C(=O)Oc2c1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L10 compound treatment 305862.0 21100.0 0.43 123814.0 -132000.0 -2.75 -1.6454 -0.5904 2060234 SPBio_000228 COC(=O)c1c(C)c2Oc3c(Cl)c(O)c(Cl)c(C)c3C(=O)Oc2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L11 compound treatment 276097.0 -8710.0 -0.18 236287.0 -19700.0 -0.41 -0.4152 -0.9289 2060040 SPBio_000229 CCOC(=O)C1(O)Oc2cc(OC)cc(OC)c2C(=O)C1c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L12 compound treatment 31753.0 -253000.0 -5.13 3056.0 -253000.0 -5.27 -7.3536 -0.9999 2069327 SPBio_000230 COC/1=CC(=O)C(=C\C1=C/C=C/c2ccccc2)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L13 compound treatment 178778.0 -106000.0 -2.15 23704.0 -232000.0 -4.84 -4.9419 -0.9333 2069243 SPBio_000231 O/C(=C\C(=O)c1ccccc1O)/c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L14 compound treatment 454608.0 170000.0 3.44 214700.0 -41300.0 -0.86 1.8258 0.5145 3173492 SPBio_000232 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(O)ccc3-c2c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L15 compound treatment 336388.0 51600.0 1.05 288453.0 32500.0 0.68 1.2175 0.9777 2060463 SPBio_000233 COc1ccc(cc1)c2coc3c(OC)c(OC)cc(O)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L16 compound treatment 341617.0 56800.0 1.15 214627.0 -41400.0 -0.86 0.205 0.1425 2081025 SPBio_000234 C[C@H]1CCC[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L17 compound treatment 292161.0 7360.0 0.15 273836.0 17800.0 0.37 0.3682 0.9196 3172979 SPBio_000235 C[C@H]1C2C(CC3C4CC=C5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CC[C@@H](C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L18 compound treatment 313834.0 29000.0 0.59 225667.0 -30300.0 -0.63 -0.0307 -0.0355 3058525 SPBio_000236 COc1cc2OC[C@H]3Oc4c5C=CC(C)(C)Oc5ccc4C(=O)[C@H]3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L19 compound treatment 281192.0 -3610.0 -0.07 273155.0 17200.0 0.36 0.2009 0.5508 923 SPBio_000237 NC(=O)NC1NC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L20 compound treatment 199918.0 -84900.0 -1.72 203865.0 -52100.0 -1.09 -1.9848 -0.9754 3077176 SPBio_000238 COc1ccc(c(O)c1O)c2coc3cc(O)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L21 compound treatment 328713.0 43900.0 0.89 279092.0 23100.0 0.48 0.9696 0.9583 3198310 SPBio_000239 COc1ccc([C@H]2COc3c(OC)c(O)ccc3C2)c(OC)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L22 compound treatment 256406.0 -28400.0 -0.58 243004.0 -13000.0 -0.27 -0.5985 -0.9408 3077177 SPBio_000240 CC(=O)OCC(O)CC(=O)CCCCCCCCCCCC#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L23 mock treatment 331106.0 46300.0 0.94 270278.0 14300.0 0.3 0.8741 0.8877 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 L24 mock treatment 261423.0 -23400.0 -0.47 238647.0 -17400.0 -0.36 -0.5908 -0.9911 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M01 mock treatment 264046.0 -20800.0 -0.42 209373.0 -46600.0 -0.97 -0.9844 -0.9299 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M02 mock treatment 281215.0 -3590.0 -0.07 286793.0 30800.0 0.64 0.4022 0.6229 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M03 compound treatment 294320.0 9520.0 0.19 295359.0 39400.0 0.82 0.7162 0.8502 3177464 SPBio_000241 NCCCC(N)CC(=O)NCC1NC(=O)C(CO)NC(=O)C(N)CNC(=O)C(NC(=O)/C(=C\NC(=O)N)/NC1=O)C2CCNC(=N)N2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M04 compound treatment 276858.0 -7950.0 -0.16 287177.0 31200.0 0.65 0.3454 0.5161 984 SPBio_000242 C[C@H]1CC2C3CC[C@H](C(=O)C)[C@@]3(C)C[C@H](O)C2[C@@]4(C)CCC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M05 compound treatment 286812.0 2010.0 0.04 253755.0 -2240.0 -0.05 -0.0043 -0.0689 1149 SPBio_000243 CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M06 compound treatment 3792.0 -281000.0 -5.7 4233.0 -252000.0 -5.25 -7.7371 -0.9991 1011303 SPBio_000244 CN1CCc2cccc-3c2C1Cc4ccc(O)c(O)c43 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M07 compound treatment 270185.0 -14600.0 -0.3 292141.0 36100.0 0.75 0.3228 0.399 3173471 SPBio_000245 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2CC[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M08 compound treatment 2830.0 -282000.0 -5.72 2958.0 -253000.0 -5.27 -7.7697 -0.9992 980 SPBio_000246 C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=C(C(=O)N)C(=O)[C@@]3(O)C(=C2C(=O)c4c(O)cccc14)O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M09 compound treatment 291918.0 7110.0 0.14 282520.0 26500.0 0.55 0.4927 0.8628 430 SPBio_000247 NC(=O)NO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M10 compound treatment 177440.0 -107000.0 -2.18 152989.0 -103000.0 -2.15 -3.0565 -1.0 1481 SPBio_000248 Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc4ccccc14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M11 compound treatment 290409.0 5600.0 0.11 232451.0 -23500.0 -0.49 -0.2665 -0.5293 1295 SPBio_000249 OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M12 compound treatment 2273.0 -283000.0 -5.73 2419.0 -254000.0 -5.28 -7.7856 -0.9992 3045196 SPBio_000250 CC1(C)S[C@@H]2[C@H](NC(=O)[C@@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M13 compound treatment 225336.0 -59500.0 -1.21 168033.0 -88000.0 -1.83 -2.1483 -0.9794 892 SPBio_000251 C[n+]1c2cc(N)ccc2cc3ccc(N)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M14 compound treatment 337953.0 53100.0 1.08 325382.0 69400.0 1.45 1.784 0.9895 1309 SPBio_000252 Cc1cc(C2CCCCC2)n(O)c(=O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M15 compound treatment 281582.0 -3220.0 -0.07 276625.0 20600.0 0.43 0.2577 0.5928 1437 SPBio_000253 CS(=O)(=O)OCCCCOS(=O)(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M16 compound treatment 263115.0 -21700.0 -0.44 230413.0 -25600.0 -0.53 -0.6878 -0.9954 1110 SPBio_000254 C[C@H]1CC2C3CC[C@](OC(=O)C)(C(=O)C)[C@@]3(C)CCC2[C@@]4(C)CCC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M17 compound treatment 273443.0 -11400.0 -0.23 267976.0 12000.0 0.25 0.0136 0.04 1198 SPBio_000255 Cn1cnc([N+](=O)[O-])c1Sc2[nH]cnc3ncnc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M18 compound treatment 60331.0 -224000.0 -4.55 21361.0 -235000.0 -4.89 -6.6743 -0.9994 1138 SPBio_000256 CC/C(=C(/CC)\c1ccc(O)cc1)/c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M19 compound treatment 2041.0 -283000.0 -5.73 2835.0 -253000.0 -5.27 -7.7828 -0.9991 3174477 SPBio_000257 CN[C@H](CC(C)C)C(=O)NC1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]6CC(=O)C(NC(=O)[C@@H]4NC(=O)[C@H](CC(=O)N)NC1=O)c7ccc(O)c(c7)-c8c(O)cc(O)cc8[C@@H](NC6=O)C(=O)O)c3O[C@@H]9OC(CO)[C@@H](O)[C@H](O)[C@H]9O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)c(Cl)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M20 compound treatment 253341.0 -31500.0 -0.64 240215.0 -15800.0 -0.33 -0.6835 -0.9525 982 SPBio_000258 CC(=O)Oc1ccc(cc1)C(c2ccc(OC(=O)C)cc2)c3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M21 compound treatment 265978.0 -18800.0 -0.38 231239.0 -24800.0 -0.52 -0.6346 -0.989 707 SPBio_000259 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CCC6C5CC[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M22 compound treatment 2619.0 -282000.0 -5.72 2604.0 -253000.0 -5.28 -7.7779 -0.9992 2114344 SPBio_000260 CC1=C(O)C(=O)C=C2C1=CC=C3[C@@]2(C)CC[C@@]4(C)[C@@H]5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M23 mock treatment 291065.0 6260.0 0.13 237485.0 -18500.0 -0.39 -0.183 -0.4506 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 M24 mock treatment 253923.0 -30900.0 -0.63 221878.0 -34100.0 -0.71 -0.9453 -0.998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N01 mock treatment 315496.0 30700.0 0.62 254630.0 -1370.0 -0.03 0.4198 0.674 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N02 mock treatment 370037.0 85200.0 1.73 309592.0 53600.0 1.12 2.0113 0.9777 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N03 compound treatment 422207.0 137000.0 2.79 290828.0 34800.0 0.73 2.4828 0.8625 970 SPBio_000261 CC1(C)O[C@]2(C)CC[C@H]1CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N04 compound treatment 392766.0 108000.0 2.19 284019.0 28000.0 0.58 1.9604 0.8654 2060424 SPBio_000262 C[C@@]12CC[C@@H](O)C[C@H]2CCc3ccccc31 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N05 compound treatment 416310.0 132000.0 2.67 293890.0 37900.0 0.79 2.4433 0.8788 893 SPBio_000263 NCC(O)c1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N06 compound treatment 270141.0 -14700.0 -0.3 265927.0 9930.0 0.21 -0.0639 -0.1766 2060300 SPBio_000264 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O)c(c4cc(ccc4OC)c5cc(=O)c6c(O)cc(O)cc6o5)c3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N07 compound treatment 390460.0 106000.0 2.14 280161.0 24200.0 0.5 1.8705 0.8501 2060025 SPBio_000265 CC(=O)O[C@H]1C[C@@]2(C)[C@@H](OC(=O)[C@H]3O[C@]32[C@]4(C)[C@@H](CC5C(C)(C)[C@@H](C[C@H](OC(=O)C)[C@]5(C)C14)OC(=O)C)OC(=O)C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N08 compound treatment 363225.0 78400.0 1.59 285416.0 29400.0 0.61 1.5575 0.9141 1010471 SPBio_000266 O=c1ccc2ccccc2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N09 compound treatment 408655.0 124000.0 2.51 301850.0 45900.0 0.96 2.4509 0.9123 3173997 SPBio_000267 COC(=O)CC1C(C)(C)C(=O)C=CC1(C)C2CC[C@@]3(C)[C@@H](OC(=O)C4OC43C2=C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N10 compound treatment 2991.0 -282000.0 -5.71 2956.0 -253000.0 -5.27 -7.7674 -0.9992 2060107 SPBio_000268 COC1=C(OC)C(=O)C(=CC1=O)[C@H](C=C)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N11 compound treatment 276396.0 -8410.0 -0.17 200656.0 -55300.0 -1.15 -0.9358 -0.8029 3054122 SPBio_000269 CC(=O)O[C@@H]1C[C@@]2(C)[C@@H](C[C@H]3O[C@]32[C@@]4(C)C1[C@@]5(C)C=CC(=O)C(C)(C)C5=C(O)C4=O)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N12 compound treatment 404541.0 120000.0 2.43 279179.0 23200.0 0.48 2.0579 0.8315 2060113 SPBio_000270 Cc1cc(O)cc(O)c1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N13 compound treatment 381276.0 96500.0 1.96 243250.0 -12700.0 -0.27 1.1951 0.6055 2060028 SPBio_000271 COC(=O)C[C@H]1C2(C)CC3(OC4(C)O[C@@]56[C@H](OC(=O)C)[C@@]3(O)C2OC(=O)C(C)C)[C@]1(C)[C@@]6(O4)[C@H](OC(=O)C)C(OC(=O)C)[C@@]7(C)[C@@H](OC(=O)/C(=C(\O)/C(C)C)/C57)c8ccoc8 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N14 compound treatment 313275.0 28500.0 0.58 196666.0 -59300.0 -1.24 -0.4659 -0.3415 2060136 SPBio_000272 CC(=C)c1cc2cc(C(=O)C)c(O)cc2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N15 compound treatment 332634.0 47800.0 0.97 288441.0 32400.0 0.68 1.1636 0.9844 2060030 SPBio_000273 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2CC3C(CC[C@@]4(C)[C@@H](OC(=O)C=C34)c5ccoc5)[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N16 compound treatment 246962.0 -37800.0 -0.77 252388.0 -3610.0 -0.08 -0.5957 -0.7727 1049466 SPBio_000274 COc1cc(C)c2C(=O)Oc3c(C)c(O)c4C(=O)OC(O)c4c3Oc2c1C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N17 compound treatment 235845.0 -49000.0 -0.99 139453.0 -117000.0 -2.43 -2.4187 -0.9221 2060031 SPBio_000275 C[C@]12CCC3[C@@]4(C)C=CC(=O)C(C)(C)C4=C(O)C(=O)[C@@]3(C)[C@]25O[C@@H]5C[C@H]1c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N18 compound treatment 297072.0 12300.0 0.25 253934.0 -2060.0 -0.04 0.1454 0.5763 1086162 SPBio_000276 COc1c2ccoc2c(OC)c3oc(=O)ccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N19 compound treatment 290891.0 6090.0 0.12 244142.0 -11900.0 -0.25 -0.0874 -0.3166 2060035 SPBio_000277 CC1(C)C2C[C@@H](O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)[C@@]2(C)C=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N20 compound treatment 250318.0 -34500.0 -0.7 231364.0 -24600.0 -0.51 -0.8573 -0.9884 3077178 SPBio_000278 CC1CCC2(C)C(CCC=C2C)C1(C)CC/C(=C/Cn3c[n+](C)c4c(N)ncnc34)/C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N21 compound treatment 280551.0 -4250.0 -0.09 244117.0 -11900.0 -0.25 -0.236 -0.9004 2060230 SPBio_000279 CC(=O)O[C@H]1C[C@@H](O)C(C)(C)C2C[C@@H](OC(=O)C)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)[C@@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N22 compound treatment 269618.0 -15200.0 -0.31 238895.0 -17100.0 -0.36 -0.4697 -0.9974 2069254 SPBio_000280 CCCCCc1c(C(=O)O)c(O)cc2OC(=O)c3c(cc(OC)cc3Oc12)C(=O)CCCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N23 mock treatment 258190.0 -26600.0 -0.54 240064.0 -15900.0 -0.33 -0.6163 -0.9728 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 N24 mock treatment 266509.0 -18300.0 -0.37 233316.0 -22700.0 -0.47 -0.5964 -0.9928 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O01 mock treatment 219279.0 -65500.0 -1.33 250568.0 -5430.0 -0.11 -1.0193 -0.7646 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O02 mock treatment 281803.0 -3000.0 -0.06 280561.0 24600.0 0.51 0.3188 0.6187 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O03 compound treatment 333790.0 49000.0 0.99 314956.0 59000.0 1.23 1.5707 0.9944 3173595 SPBio_000281 C[C@H]1OC(OC/2CC3O[C@@](O)(CC(O)C3C(=O)O)CC(O)C(O)CCC(O)CC(O)CC(O)CC(=O)O[C@@H](C)C(C)[C@H](O)[C@@H](C)/C=C/C=C/CC\C=C\C=C\C=C\C=C2)[C@@H](O)[C@@H](N)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O04 compound treatment 319604.0 34800.0 0.71 298695.0 42700.0 0.89 1.1278 0.9934 1002775 SPBio_000282 Cc1cccc(C(=O)O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O05 compound treatment 276667.0 -8140.0 -0.16 271730.0 15700.0 0.33 0.1151 0.3137 1000036 SPBio_000283 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3C2C[C@@H]1CC4NCCc5cc(OC)c(OC)cc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O06 compound treatment 139121.0 -146000.0 -2.95 185611.0 -70400.0 -1.47 -3.1253 -0.9478 3058740 SPBio_000284 CC(=O)O[C@@H]1CC[C@@]2(C)[C@@H](CCC3C4CCC(=O)[C@@]4(C)CCC32)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O07 compound treatment 7087.0 -278000.0 -5.63 6867.0 -249000.0 -5.19 -7.6511 -0.9992 1383 SPBio_000285 CC[C@H]([C@H]1CC[C@H](C)[C@@H](O1)[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@H]2OC3(O[C@@]4(CC[C@](C)(O4)[C@H]5CC[C@](O)(CC)[C@H](C)O5)[C@H](O)C=C3)[C@H](C)C[C@@H]2C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O08 compound treatment 89760.0 -195000.0 -3.95 19745.0 -236000.0 -4.92 -6.2763 -0.9941 943 SPBio_000286 CCCCC1C(=O)N(N(C1=O)c2ccc(O)cc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O09 compound treatment 255916.0 -28900.0 -0.59 254466.0 -1530.0 -0.03 -0.4367 -0.7446 1260 SPBio_000287 N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O10 compound treatment 270673.0 -14100.0 -0.29 279419.0 23400.0 0.49 0.1424 0.2517 1282 SPBio_000288 NS(=O)(=O)c1cc2c(N=CNS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O11 compound treatment 271589.0 -13200.0 -0.27 285369.0 29400.0 0.61 0.2432 0.3641 1352 SPBio_000289 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O12 compound treatment 227253.0 -57600.0 -1.17 239624.0 -16400.0 -0.34 -1.0662 -0.8771 1020 SPBio_000290 NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(=N)N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O13 compound treatment 1846.0 -283000.0 -5.74 2865.0 -253000.0 -5.27 -7.7852 -0.9991 720 SPBio_000291 Fc1c[nH]c(=O)[nH]c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O14 compound treatment 294589.0 9780.0 0.2 282778.0 26800.0 0.56 0.5348 0.9031 2069230 SPBio_000292 CN(C)CC[C@H](c1ccc(Cl)cc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O15 compound treatment 270846.0 -14000.0 -0.28 257095.0 1100.0 0.02 -0.1839 -0.6479 1154 SPBio_000293 O=C1CC2OCC=C3CN4CC[C@]56C4C[C@@H]3[C@@H]2C6N1c7ccccc75 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O16 compound treatment 274191.0 -10600.0 -0.22 276784.0 20800.0 0.43 0.154 0.3186 877 SPBio_000294 CC(C)(Oc1ccc(Cl)cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O17 compound treatment 4250.0 -281000.0 -5.69 3000.0 -253000.0 -5.27 -7.7487 -0.9993 3177389 SPBio_000295 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O18 compound treatment 269673.0 -15100.0 -0.31 272582.0 16600.0 0.35 0.0274 0.0593 907 SPBio_000296 OC(=O)c1cc(O)c2cccc(O)c2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O19 compound treatment 189865.0 -94900.0 -1.92 113545.0 -142000.0 -2.97 -3.4595 -0.978 1288 SPBio_000297 CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O)[C@H](C)O2)N(C)C)c3c(O)c4C(=O)c5c(O)cccc5C(=O)c4cc3[C@H]1C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O20 compound treatment 268818.0 -16000.0 -0.32 242883.0 -13100.0 -0.27 -0.4224 -0.9964 1006 SPBio_000298 Nc1ccn(C2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O21 compound treatment 5957.0 -279000.0 -5.65 2815.0 -253000.0 -5.27 -7.727 -0.9994 3174227 SPBio_000299 CC[C@@H]1[C@@H](O)N2[C@H]3C[C@@]45C(O)C3[C@@H]1CC2[C@@H]5N(C)c6ccccc64 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O22 compound treatment 302090.0 17300.0 0.35 294128.0 38100.0 0.79 0.8095 0.9324 3077148 SPBio_000300 CCCCC(=O)Oc1ccccc1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O23 mock treatment 287670.0 2870.0 0.06 249800.0 -6200.0 -0.13 -0.0502 -0.3548 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 O24 mock treatment 293293.0 8490.0 0.17 240548.0 -15500.0 -0.32 -0.1059 -0.2902 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P01 mock treatment 300484.0 15700.0 0.32 256896.0 897.0 0.02 0.238 0.7474 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P02 mock treatment 345893.0 61100.0 1.24 263492.0 7490.0 0.16 0.9861 0.79 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P03 compound treatment 303474.0 18700.0 0.38 252279.0 -3720.0 -0.08 0.2128 0.5509 2060147 SPBio_000301 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P04 compound treatment 361430.0 76600.0 1.55 301605.0 45600.0 0.95 1.7703 0.9722 2060138 SPBio_000302 C[C@]1([C@H]2[C@H](C(=O)O)[C@]3(CC(=C)[C@@]4(O)C3)[C@@H](CC4)[C@]52OC1=O)[C@@H](O)C=C5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P05 compound treatment 413243.0 128000.0 2.6 304875.0 48900.0 1.02 2.5612 0.9161 2060038 SPBio_000303 COC(=O)C[C@H]1C(C)(C)C(=O)C=C[C@]1(C)C2CC[C@@]3(C)[C@@H](OC(=O)C=C3C2=C)c4ccoc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P06 compound treatment 453332.0 169000.0 3.42 260319.0 4320.0 0.09 2.4795 0.7255 1098 SPBio_000304 C[C@@]12C[C@H](O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P07 compound treatment 328679.0 43900.0 0.89 252836.0 -3160.0 -0.07 0.5824 0.6529 2060055 SPBio_000305 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P08 compound treatment 393486.0 109000.0 2.2 285541.0 29500.0 0.62 1.9932 0.8713 2060140 SPBio_000306 COc1cc2occc2c3oc(=O)ccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P09 compound treatment 375905.0 91100.0 1.85 267614.0 11600.0 0.24 1.477 0.793 1609 SPBio_000307 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P10 compound treatment 406331.0 122000.0 2.46 292546.0 36500.0 0.76 2.2805 0.8844 2060142 SPBio_000308 CC(=O)OC1C/C(=C/CC/C(=C/CC[C@](C)(O)C2CC1C(=C)C(=O)O2)/C)/C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P11 compound treatment 391983.0 107000.0 2.17 270469.0 14500.0 0.3 1.7496 0.7976 2060059 SPBio_000309 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](C[C@H]5O[C@]543)c6ccoc6)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P12 compound treatment 354122.0 69300.0 1.41 309488.0 53500.0 1.11 1.7816 0.9934 3059434 SPBio_000310 C[C@]12CC[C@@H]3[C@H](CC3(C)C)C(=O)CC[C@H]2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P13 compound treatment 339795.0 55000.0 1.11 241205.0 -14800.0 -0.31 0.5704 0.4931 2060060 SPBio_000311 CC1(C)C2CC(=O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)[C@@]2(C)C=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P14 compound treatment 362426.0 77600.0 1.57 285405.0 29400.0 0.61 1.5459 0.9155 2060170 SPBio_000312 CC(=O)OC1CCC2(O)CC1(C)CCC3C2CC3(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P15 compound treatment 316506.0 31700.0 0.64 236563.0 -19400.0 -0.4 0.1681 0.2213 2060062 SPBio_000313 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P16 compound treatment 288512.0 3710.0 0.08 259012.0 3010.0 0.06 0.0975 0.996 2060421 SPBio_000314 C[C@](O)(CCC1C(=C)C[C@H](O)C2C(C)(C)CCCC12C)C=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P17 compound treatment 313554.0 28700.0 0.58 259389.0 3390.0 0.07 0.4621 0.787 2060063 SPBio_000315 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](C(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P18 compound treatment 315163.0 30400.0 0.62 243471.0 -12500.0 -0.26 0.2506 0.3749 3177379 SPBio_000316 CC(=O)O[C@H]1CC(=C)C(CC[C@](C)(O)C=C)C2(C)CCCC(C)(C)C12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P19 compound treatment 285753.0 949.0 0.02 244280.0 -11700.0 -0.24 -0.159 -0.6494 2060066 SPBio_000317 COC(=O)CC1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P20 compound treatment 294882.0 10100.0 0.2 290837.0 34800.0 0.73 0.6577 0.8723 2060175 SPBio_000318 C[C@](O)(CCC1C(=C)CCC2[C@@](C)(CO)CCC[C@]12C)C=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P21 compound treatment 271735.0 -13100.0 -0.26 249204.0 -6790.0 -0.14 -0.2874 -0.9569 3173867 SPBio_000319 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P22 compound treatment 254843.0 -30000.0 -0.61 257547.0 1550.0 0.03 -0.4067 -0.6686 2060166 SPBio_000320 CC1(C)CC2C1CCC(=C)/C(=N\O)/CCC2=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P23 mock treatment 266842.0 -18000.0 -0.36 237006.0 -19000.0 -0.4 -0.5373 -0.9991 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2158 P24 mock treatment 300778.0 16000.0 0.32 242837.0 -13200.0 -0.27 0.0351 0.0827 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A01 mock treatment 251438.0 -10500.0 -0.21 237907.0 -28700.0 -0.6 -0.5729 -0.9032 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A02 mock treatment 245375.0 -16600.0 -0.34 235168.0 -31400.0 -0.65 -0.7002 -0.9518 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A03 compound treatment 194082.0 -67800.0 -1.38 194959.0 -71600.0 -1.49 -2.0278 -0.9992 1030891 SPBio_000321 Cc1cc(=O)oc2c(O)c(O)ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A04 compound treatment 260724.0 -1200.0 -0.02 265115.0 -1480.0 -0.03 -0.039 -0.9934 1109169 SPBio_000322 COc1ccc2c(=O)c(coc2c1)c3cc4OCOc4cc3OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A05 compound treatment 237166.0 -24800.0 -0.5 267111.0 520.0 0.01 -0.3473 -0.6917 1552436 SPBio_000323 COc1ccc(cc1)c2cc(=O)c3cc(OC)ccc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A06 compound treatment 216002.0 -45900.0 -0.93 249939.0 -16700.0 -0.35 -0.9036 -0.9095 2060405 SPBio_000324 CC1(C)[C@H](CC(=O)O)[C@@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]3(O)C[C@@H](C1=O)C2=O)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A07 compound treatment 242287.0 -19600.0 -0.4 240040.0 -26600.0 -0.55 -0.6726 -0.987 2060323 SPBio_000325 COc1ccccc1c2cc(=O)c3c(OC)cccc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A08 compound treatment 199136.0 -62800.0 -1.27 218682.0 -47900.0 -1.0 -1.6058 -0.9928 2060179 SPBio_000326 COc1cccc2c1CCC3CC(=O)CC[C@@]32C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A09 compound treatment 234913.0 -27000.0 -0.55 249805.0 -16800.0 -0.35 -0.6345 -0.9765 1499608 SPBio_000327 COc1ccc2c(=O)cc(oc2c1)c3ccccc3OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A10 compound treatment 232542.0 -29400.0 -0.6 244492.0 -22100.0 -0.46 -0.7468 -0.9919 3077346 SPBio_000328 COC(=O)c1c(C)cc(OC)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A11 compound treatment 240706.0 -21200.0 -0.43 232876.0 -33700.0 -0.7 -0.8008 -0.9723 777 SPBio_000329 Oc1ccc(cc1)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A12 compound treatment 243279.0 -18600.0 -0.38 270754.0 4160.0 0.09 -0.206 -0.5311 1009851 SPBio_000330 O=C1c2ccccc2C(=O)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A13 compound treatment 255046.0 -6880.0 -0.14 278827.0 12200.0 0.25 0.0816 0.2809 2060418 SPBio_000331 COc1ccccc1c2cc(=O)c3cccc(OC)c3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A14 compound treatment 208905.0 -53000.0 -1.07 264577.0 -2010.0 -0.04 -0.7897 -0.7341 2060380 SPBio_000332 CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3(F)[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A15 compound treatment 239464.0 -22500.0 -0.46 250322.0 -16300.0 -0.34 -0.5617 -0.9894 2060322 SPBio_000333 COc1ccc2c(=O)c(OC)c(oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A16 compound treatment 240173.0 -21800.0 -0.44 238817.0 -27800.0 -0.58 -0.721 -0.991 2579 SPBio_000334 OCCSCCO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A17 compound treatment 246708.0 -15200.0 -0.31 235715.0 -30900.0 -0.64 -0.673 -0.9434 3173852 SPBio_000335 COc1ccc(CCC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO)C(O)[C@H](O)C3O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)cc2O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A18 compound treatment 229380.0 -32500.0 -0.66 229863.0 -36700.0 -0.77 -1.0076 -0.9973 3173468 SPBio_000336 COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A19 compound treatment 250497.0 -11400.0 -0.23 235199.0 -31400.0 -0.65 -0.6263 -0.9026 3177315 SPBio_000337 CC1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A20 compound treatment 224891.0 -37000.0 -0.75 218382.0 -48200.0 -1.0 -1.2411 -0.9897 1445 SPBio_000338 C/C=C(/C)\C(=O)O[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@H]4[C@@]2(C[C@@]5(O)[C@@H]6CN7C[C@@H](C)CC[C@H]7[C@@](C)(O)[C@@]6(O)[C@@H](O)C[C@@]45O)O[C@@]31O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A21 compound treatment 238464.0 -23500.0 -0.48 258318.0 -8270.0 -0.17 -0.4582 -0.9057 976 SPBio_000339 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A22 compound treatment 229481.0 -32400.0 -0.66 234641.0 -31900.0 -0.67 -0.9358 -1.0 1112405 SPBio_000340 COc1cc2OCOc2cc1c3cc4cc5ccoc5cc4oc3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A23 mock treatment 232347.0 -29600.0 -0.6 245788.0 -20800.0 -0.43 -0.7305 -0.9873 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 A24 mock treatment 197627.0 -64300.0 -1.3 228815.0 -37800.0 -0.79 -1.4782 -0.9708 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B01 mock treatment 271706.0 9780.0 0.2 254009.0 -12600.0 -0.26 -0.0451 -0.1374 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B02 mock treatment 248922.0 -13000.0 -0.26 254782.0 -11800.0 -0.25 -0.3604 -0.9994 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B03 compound treatment 4009.0 -258000.0 -5.23 3532.0 -263000.0 -5.48 -7.5724 -0.9997 1011006 SPBio_000341 O=C1C=CC(=O)c2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B04 compound treatment 294547.0 32600.0 0.66 266905.0 314.0 0.01 0.4723 0.7141 3172845 SPBio_000342 CCC(C)C(=O)O[C@H]1[C@H](O)C2C(CN3CC(C)CCC3[C@@]2(C)O)C4C[C@]5(O[C@@]6(O)C7C(OC(=O)C)[C@@H](OC(=O)C)C5[C@@]41O)[C@@]7(C)CCC6OC(=O)C(C)(O)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B05 compound treatment 277548.0 15600.0 0.32 289769.0 23200.0 0.48 0.5654 0.9791 1000322 SPBio_000343 CCOC(=O)[C@H](CCc1ccccc1)N[C@H]2CCc3ccccc3N(CC(=O)O)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B06 compound treatment 274465.0 12500.0 0.25 269095.0 2500.0 0.05 0.2166 0.8348 2060143 SPBio_000344 COC1=CC(=O)C(=CC1=O)C(C=C)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B07 compound treatment 300224.0 38300.0 0.78 269903.0 3310.0 0.07 0.5978 0.7669 1001496 SPBio_000345 NC(=O)N1c2ccccc2CC(=O)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B08 compound treatment 258508.0 -3420.0 -0.07 288236.0 21600.0 0.45 0.2699 0.5915 1046 SPBio_000346 CC1C2C(CC3C4CC[C@H]5C[C@@H](O)CC[C@]5(C)C4CC(=O)[C@]23C)OC61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B09 compound treatment 279772.0 17800.0 0.36 300942.0 34400.0 0.72 0.7619 0.9501 3198312 SPBio_000347 C[C@@]12CCC3C(C=CC4=CC(=O)CC[C@]34C)C2CC[C@]51CCC(=O)O5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B10 compound treatment 282607.0 20700.0 0.42 296735.0 30100.0 0.63 0.7405 0.9807 2060339 SPBio_000348 COc1cc2N3C4[C@H]5[C@H]6C[C@@H]7N(CC[C@@]74c2cc1OC)CC6=CCOC5CC3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B11 compound treatment 2809.0 -259000.0 -5.25 3278.0 -263000.0 -5.49 -7.5934 -0.9998 2069295 SPBio_000349 CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc4ccc(cc4)c5ccccc5c6nnn[nH]6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B12 compound treatment 189565.0 -72400.0 -1.47 237762.0 -28800.0 -0.6 -1.462 -0.9223 3059432 SPBio_000350 CC(C)CCCC(C)[C@H]1CCC2C3C(CC[C@]12C)[C@@]4(C)CC[C@H](O)CC4=CC3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B13 compound treatment 297591.0 35700.0 0.72 304497.0 37900.0 0.79 1.0697 0.999 3480246 SPBio_000351 CCOC(=O)C1=C(COCCN)NC(=C(C1c2ccccc2Cl)C(=O)OC)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B14 compound treatment 222627.0 -39300.0 -0.8 211469.0 -55100.0 -1.15 -1.3754 -0.984 2060325 SPBio_000352 COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(c34)-c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B15 compound treatment 2972.0 -259000.0 -5.25 3411.0 -263000.0 -5.48 -7.5891 -0.9998 1001366 SPBio_000353 COc1c(N2CCNC(C)C2)c(F)cc3c(=O)c(cn(C4CC4)c13)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B16 compound treatment 282923.0 21000.0 0.43 288456.0 21900.0 0.46 0.6231 0.9994 2060251 SPBio_000354 NCC(N)C(=O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B17 compound treatment 254050.0 -7880.0 -0.16 263175.0 -3420.0 -0.07 -0.1632 -0.9337 3198313 SPBio_000355 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@]43C)[C@@H]2[C@H]1C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B18 compound treatment 281041.0 19100.0 0.39 275287.0 8700.0 0.18 0.4021 0.94 297849 SPBio_000356 COc1ccc2c(c1)[nH]c3c(C)nccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B19 compound treatment 257345.0 -4580.0 -0.09 271304.0 4710.0 0.1 0.0038 0.0278 1001346 SPBio_000357 OC(CC[C@@H]1[C@H](N(C1=O)c2ccc(F)cc2)c3ccc(O)cc3)c4ccc(F)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B20 compound treatment 245796.0 -16100.0 -0.33 277493.0 10900.0 0.23 -0.0706 -0.1774 2060051 SPBio_000358 Cc1cc(=O)c2c(O)cc(O)c(C)c2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B21 compound treatment 209594.0 -52300.0 -1.06 205438.0 -61200.0 -1.27 -1.651 -0.9959 1333 SPBio_000359 CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(Cc2ccccc2)NC(=O)C(CCN)NC1=O)C(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B22 compound treatment 270351.0 8430.0 0.17 203569.0 -63000.0 -1.31 -0.8076 -0.61 956 SPBio_000360 CCn1nc(C(=O)O)c(=O)c2cc3OCOc3cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B23 mock treatment 289132.0 27200.0 0.55 263864.0 -2730.0 -0.06 0.3498 0.6309 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 B24 mock treatment 240462.0 -21500.0 -0.44 220601.0 -46000.0 -0.96 -0.9852 -0.9362 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C01 mock treatment 254690.0 -7240.0 -0.15 267826.0 1240.0 0.03 -0.0855 -0.5743 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C02 mock treatment 262265.0 339.0 0.01 271178.0 4590.0 0.1 0.0724 0.756 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C03 compound treatment 15066.0 -247000.0 -5.0 19981.0 -247000.0 -5.14 -7.1716 -0.9999 2060213 SPBio_000361 CC1(C)C2CC(=O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)[C@@]2(C)[C@H]6O[C@H]6C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C04 compound treatment 14024.0 -248000.0 -5.03 20582.0 -246000.0 -5.13 -7.1777 -1.0 1530 SPBio_000362 COc1ccc2c3CCN=C(C)c3[nH]c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C05 compound treatment 106792.0 -155000.0 -3.15 120498.0 -146000.0 -3.04 -4.376 -0.9999 3173352 SPBio_000363 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C06 compound treatment 61899.0 -200000.0 -4.06 63814.0 -203000.0 -4.22 -5.8545 -0.9998 2060407 SPBio_000364 COc1ccc(/C=C/C(=O)O)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C07 compound treatment 306084.0 44200.0 0.9 303616.0 37000.0 0.77 1.1784 0.9972 2060232 SPBio_000365 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C08 compound treatment 171075.0 -90900.0 -1.84 132667.0 -134000.0 -2.79 -3.2752 -0.9797 2060504 SPBio_000366 Cc1cc(O)c(C)c(O)c1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C09 compound treatment 263404.0 1480.0 0.03 293739.0 27100.0 0.57 0.4211 0.7435 2060233 SPBio_000367 COC(=O)C[C@H]1C(C)(C)[C@H](O)[C@@H]2CC3=C4CC(O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C10 compound treatment 269262.0 7340.0 0.15 275291.0 8700.0 0.18 0.2333 0.9952 2060400 SPBio_000368 CC(C)c1ccc2c(CCC3[C@](C)(CN)CCC[C@@]32C)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C11 compound treatment 257818.0 -4110.0 -0.08 279158.0 12600.0 0.26 0.1262 0.4595 2060235 SPBio_000369 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)[C@@H]3O[C@@H]3[C@]2(C)C4CC[C@@]5(C)[C@@H](OC(=O)C=C5[C@]14C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C12 compound treatment 258941.0 -2980.0 -0.06 268157.0 1570.0 0.03 -0.0197 -0.2868 2060317 SPBio_000370 COc1cc(OC)c2c(OC)c(c3ccc4OCOc4c3)c(=O)oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C13 compound treatment 260505.0 -1420.0 -0.03 263592.0 -3000.0 -0.06 -0.0645 -0.9382 2060237 SPBio_000371 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)C(=O)O)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C14 compound treatment 259197.0 -2730.0 -0.06 293317.0 26700.0 0.56 0.3546 0.6337 891 SPBio_000372 CC(=O)OCC(=O)[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C15 compound treatment 248124.0 -13800.0 -0.28 261421.0 -5170.0 -0.11 -0.274 -0.9139 2060240 SPBio_000373 CC1=C2C(O)C(=O)OC3CC4C(C)(C)C(=O)C=C[C@]4(C)C(CC1)[C@@]32C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C16 compound treatment 250279.0 -11600.0 -0.24 255284.0 -11300.0 -0.24 -0.3335 -1.0 2060458 SPBio_000374 CC(=O)Oc1cccc(C(=O)O)c1OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C17 compound treatment 249101.0 -12800.0 -0.26 259209.0 -7380.0 -0.15 -0.2926 -0.9686 2060241 SPBio_000375 CC1(C)C2C[C@@H](O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)[C@@]2(C)CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C18 compound treatment 266756.0 4830.0 0.1 276914.0 10300.0 0.22 0.2213 0.9366 3172856 SPBio_000376 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4C(C32)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C19 compound treatment 265545.0 3620.0 0.07 268711.0 2120.0 0.04 0.0831 0.9705 2060026 SPBio_000377 COC(=O)C[C@H]1C(C)(C)[C@@H](OC(=O)C)[C@@H]2CC3C(CC[C@@]4(C)[C@@H](OC(=O)CC34)c5ccoc5)[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C20 compound treatment 254221.0 -7700.0 -0.16 261798.0 -4790.0 -0.1 -0.1811 -0.9766 1010689 SPBio_000378 COc1cc(CC=C)c(OC)c2OCOc21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C21 compound treatment 321285.0 59400.0 1.2 308951.0 42400.0 0.88 1.4749 0.9884 2060086 SPBio_000379 CCC(C)C(=O)O[C@@H]1C[C@@]2(C)[C@@H](OC(=O)CC32OC4(C)OC53[C@H](OC(=O)C(C)C)[C@@]6(O)[C@@H](OC(=O)C7(C)OC7C)[C@@]8(C)C[C@]6(O)[C@@](C)([C@H]8CC(=O)OC)C15O4)c9ccoc9 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C22 compound treatment 264294.0 2370.0 0.05 283684.0 17100.0 0.36 0.2857 0.7952 1000142 SPBio_000380 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C23 mock treatment 252137.0 -9790.0 -0.2 263664.0 -2930.0 -0.06 -0.1834 -0.8836 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 C24 mock treatment 241694.0 -20200.0 -0.41 266162.0 -429.0 -0.01 -0.2963 -0.7223 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D01 mock treatment 287369.0 25400.0 0.52 264568.0 -2020.0 -0.04 0.3349 0.6472 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D02 mock treatment 262739.0 813.0 0.02 291127.0 24500.0 0.51 0.3731 0.7295 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D03 compound treatment 286963.0 25000.0 0.51 301026.0 34400.0 0.72 0.8662 0.9856 3078456 SPBio_000381 CC(=CCC[C@](C)(O)C1CCC(=CC1)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D04 compound treatment 299316.0 37400.0 0.76 268836.0 2250.0 0.05 0.5691 0.7493 2060067 SPBio_000382 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D05 compound treatment 276196.0 14300.0 0.29 279525.0 12900.0 0.27 0.3951 0.9994 1002856 SPBio_000383 CCC(C(=O)N)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D06 compound treatment 291067.0 29100.0 0.59 278630.0 12000.0 0.25 0.5951 0.9272 3174120 SPBio_000384 CCCCCCCCCCCC[C@@H]([C@@H](C)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D07 compound treatment 240839.0 -21100.0 -0.43 223272.0 -43300.0 -0.9 -0.9404 -0.9417 3078457 SPBio_000385 CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D08 compound treatment 280441.0 18500.0 0.38 234049.0 -32500.0 -0.68 -0.214 -0.2761 1000219 SPBio_000386 N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D09 compound treatment 297046.0 35100.0 0.71 283161.0 16600.0 0.35 0.7475 0.9448 2069284 SPBio_000387 COc1ccc2cc(ccc2c1)[C@H](C)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D10 compound treatment 259016.0 -2910.0 -0.06 280240.0 13600.0 0.28 0.1594 0.5487 3177312 SPBio_000388 CC(C)CCCC(C)C1CCC2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D11 compound treatment 2722.0 -259000.0 -5.25 2630.0 -264000.0 -5.5 -7.6042 -0.9997 1377 SPBio_000389 CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D12 compound treatment 299681.0 37800.0 0.77 304141.0 37600.0 0.78 1.0944 0.9999 1064620 SPBio_000390 COC1=CC23CCCN3CCc4cc5OCOc5cc4C2C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D13 compound treatment 297882.0 36000.0 0.73 288530.0 21900.0 0.46 0.8386 0.9747 1079 SPBio_000391 N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D14 compound treatment 273550.0 11600.0 0.24 259574.0 -7020.0 -0.15 0.0633 0.2281 1000141 SPBio_000392 OC[C@H]1O[C@@H](Oc2cc3ccc(=O)oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D15 compound treatment 273836.0 11900.0 0.24 286597.0 20000.0 0.42 0.4654 0.9663 2060414 SPBio_000393 OC(=O)c1nc2cc(Cl)c(Cl)cc2nc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D16 compound treatment 204946.0 -57000.0 -1.16 191660.0 -74900.0 -1.56 -1.9206 -0.989 2060229 SPBio_000394 Oc1cc(OC(=O)c2cc(O)c(O)c(O)c2)c3C[C@@H](OC(=O)c4cc(O)c(O)c(O)c4)[C@H](Oc3c1)c5cc(O)c(O)c(O)c5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D17 compound treatment 269109.0 7180.0 0.15 277194.0 10600.0 0.22 0.2592 0.9796 1000393 SPBio_000395 CN(C)CCc1c[nH]c2ccc(CS(=O)(=O)N3CCCC3)cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D18 compound treatment 265164.0 3240.0 0.07 294252.0 27700.0 0.58 0.4539 0.7826 2060137 SPBio_000396 COc1ccc(cc1)c2coc3c(OC)c(OC)cc(OC)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D19 compound treatment 261555.0 -371.0 -0.01 280075.0 13500.0 0.28 0.1933 0.6879 3055414 SPBio_000397 OC[C@@H]1CCCN2CCCC[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D20 compound treatment 266303.0 4380.0 0.09 235755.0 -30800.0 -0.64 -0.3915 -0.6037 2060196 SPBio_000398 COc1cc2OCC3Oc4cc5OC(C)(C)C=Cc5c(O)c4C(=O)C3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D21 compound treatment 253900.0 -8030.0 -0.16 240948.0 -25600.0 -0.53 -0.4928 -0.8824 2060489 SPBio_000399 C/C=C(/C)\C(=O)O[C@@H]1Cc2c(OC1(C)C)ccc3ccc(=O)oc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D22 compound treatment 244499.0 -17400.0 -0.35 238003.0 -28600.0 -0.6 -0.6709 -0.9689 3078459 SPBio_000400 CCN(CCCc1ccccc1)CCCc2ccccc2.CC(CC(=O)O)(CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D23 mock treatment 245760.0 -16200.0 -0.33 240344.0 -26200.0 -0.55 -0.6184 -0.97 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 D24 mock treatment 223444.0 -38500.0 -0.78 233433.0 -33200.0 -0.69 -1.0401 -0.9982 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E01 mock treatment 335396.0 73500.0 1.49 252824.0 -13800.0 -0.29 0.8504 0.5606 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E02 mock treatment 281418.0 19500.0 0.4 287600.0 21000.0 0.44 0.5889 0.9987 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E03 compound treatment 227733.0 -34200.0 -0.69 254543.0 -12000.0 -0.25 -0.6676 -0.9056 2060027 SPBio_000401 CC(=O)O[C@@H]1CC2C(C)(C)[C@@H](O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E04 compound treatment 266233.0 4310.0 0.09 228352.0 -38200.0 -0.8 -0.5016 -0.6259 2060441 SPBio_000402 OC(=O)c1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E05 compound treatment 326732.0 64800.0 1.31 281133.0 14500.0 0.3 1.1432 0.8479 2060029 SPBio_000403 CC(=O)O[C@H]1CC[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E06 compound treatment 284373.0 22400.0 0.46 295994.0 29400.0 0.61 0.7549 0.9893 2060452 SPBio_000404 CC1(C)O[C@@H]2C[C@](O)(C[C@@H](O)[C@@H]2O1)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E07 compound treatment 278162.0 16200.0 0.33 271218.0 4630.0 0.1 0.3009 0.8773 3173368 SPBio_000405 O=C1CC[C@]2(/C=C/C(=O)NCCCCNCCCNC(=O)\C=C\c3ccc4O[C@@H]2C1)c4c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E08 compound treatment 285560.0 23600.0 0.48 245538.0 -21100.0 -0.44 0.0287 0.0441 2060411 SPBio_000406 O[C@H]1Cc2ccc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E09 compound treatment 271417.0 9490.0 0.19 273681.0 7090.0 0.15 0.2405 0.9915 2060039 SPBio_000407 CC(=CCc1c(O)cc2oc(C)cc(=O)c2c1O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E10 compound treatment 285447.0 23500.0 0.48 264996.0 -1590.0 -0.03 0.3137 0.6562 2060392 SPBio_000408 CCOc1ccc(cc1)C(=O)c2ccc(O)c(O)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E11 compound treatment 245263.0 -16700.0 -0.34 271859.0 5270.0 0.11 -0.1613 -0.454 2060056 SPBio_000409 COc1cc(O)c2c(=O)cc(C)oc2c1CC=C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E12 compound treatment 260462.0 -1460.0 -0.03 308321.0 41700.0 0.87 0.5937 0.6826 2069228 SPBio_000410 COc1ccc2oc3ccccc3c(=O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E13 compound treatment 230449.0 -31500.0 -0.64 236827.0 -29800.0 -0.62 -0.8897 -0.9999 2060061 SPBio_000411 Cc1cc(=O)c2c(O)c3CCC(C)(C)Oc3cc2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E14 compound treatment 237102.0 -24800.0 -0.5 241143.0 -25400.0 -0.53 -0.7307 -0.9997 1050711 SPBio_000412 COc1cc(OC)cc(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E15 compound treatment 247227.0 -14700.0 -0.3 275076.0 8490.0 0.18 -0.0857 -0.2474 3058621 SPBio_000413 C[C@H]1C2[C@H](C[C@H]3C4CC=C5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CC[C@@H](C)CN6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E16 compound treatment 238942.0 -23000.0 -0.47 259065.0 -7530.0 -0.16 -0.4403 -0.8957 973 SPBio_000414 COc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E17 compound treatment 271993.0 10100.0 0.2 297367.0 30800.0 0.64 0.5977 0.8883 2060161 SPBio_000415 CC(=C)[C@H]1COc2cc3oc(=O)ccc3cc2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E18 compound treatment 201314.0 -60600.0 -1.23 211540.0 -55100.0 -1.15 -1.6798 -0.9994 360 SPBio_000416 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E19 compound treatment 231512.0 -30400.0 -0.62 274199.0 7610.0 0.16 -0.3239 -0.5088 1352641 SPBio_000417 COc1c2ccoc2nc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E20 compound treatment 232019.0 -29900.0 -0.61 260407.0 -6180.0 -0.13 -0.5198 -0.8386 2060502 SPBio_000418 COc1cc(cc(OC)c1O)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E21 compound treatment 266794.0 4870.0 0.1 271470.0 4880.0 0.1 0.1417 0.9999 2060295 SPBio_000419 CC(C)C1COc2cc3oc(=O)ccc3cc2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E22 compound treatment 2559.0 -259000.0 -5.26 2677.0 -264000.0 -5.5 -7.6058 -0.9998 862 SPBio_000420 CCCCCCCCCCCCCCCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E23 mock treatment 244960.0 -17000.0 -0.34 282791.0 16200.0 0.34 -0.0046 -0.0095 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 E24 mock treatment 227054.0 -34900.0 -0.71 262187.0 -4400.0 -0.09 -0.5648 -0.7922 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F01 mock treatment 252052.0 -9870.0 -0.2 285556.0 19000.0 0.4 0.1378 0.3112 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F02 mock treatment 269831.0 7910.0 0.16 290963.0 24400.0 0.51 0.4724 0.8872 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F03 compound treatment 318539.0 56600.0 1.15 312759.0 46200.0 0.96 1.4917 0.9961 1140 SPBio_000421 CC(=O)OC/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F04 compound treatment 336400.0 74500.0 1.51 332311.0 65700.0 1.37 2.0357 0.9988 3198317 SPBio_000422 CCOC(=O)[C@H](CCc1ccccc1)N[C@H](C)C(=O)N2[C@@H](C[C@@H]3CCCC[C@@H]32)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F05 compound treatment 290790.0 28900.0 0.59 332767.0 66200.0 1.38 1.3886 0.9272 3173234 SPBio_000423 Cn1c(=O)[nH]c(=O)c2nc[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F06 compound treatment 322667.0 60700.0 1.23 323084.0 56500.0 1.18 1.7029 0.9997 653 SPBio_000424 Oc1cc2cccc(O)c(=O)c2c(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F07 compound treatment 284246.0 22300.0 0.45 306356.0 39800.0 0.83 0.9057 0.9595 1090658 SPBio_000425 COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F08 compound treatment 292559.0 30600.0 0.62 316202.0 49600.0 1.03 1.17 0.9703 1013195 SPBio_000426 Nc1ncnc2[nH]cnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F09 compound treatment 296272.0 34300.0 0.7 282916.0 16300.0 0.34 0.7328 0.9457 1043296 SPBio_000427 Cc1nccc2c3ccc(O)cc3[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F10 compound treatment 283159.0 21200.0 0.43 317624.0 51000.0 1.06 1.0562 0.9208 3177456 SPBio_000428 CC(C)CCCC(C)[C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F11 compound treatment 277816.0 15900.0 0.32 322711.0 56100.0 1.17 1.0545 0.8695 3480229 SPBio_000429 COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F12 compound treatment 254563.0 -7360.0 -0.15 287166.0 20600.0 0.43 0.1975 0.4352 1113269 SPBio_000430 CN1Cc2c3OCOc3ccc2C4C(O)Cc5cc6OCOc6cc5C41 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F13 compound treatment 272922.0 11000.0 0.22 266616.0 25.1 0.0 0.158 0.7088 1001491 SPBio_000431 CCCc1nc(c(C(=O)OCc2oc(=O)oc2C)n1Cc3ccc(cc3)c4ccccc4c5nn[nH]n5)C(C)(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F14 compound treatment 240130.0 -21800.0 -0.44 242033.0 -24600.0 -0.51 -0.6742 -0.9973 1020463 SPBio_000432 Oc1cc2ccc(=O)oc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F15 compound treatment 270019.0 8090.0 0.16 283394.0 16800.0 0.35 0.3635 0.9404 1000878 SPBio_000433 OCCN1C[C@@H](O)[C@@H](O)C(O)C1CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F16 compound treatment 261377.0 -549.0 -0.01 308148.0 41600.0 0.87 0.6043 0.698 3174244 SPBio_000434 N=c1[nH]c(=O)c2[nH]c(=O)c(=O)[nH]c2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F17 compound treatment 262338.0 412.0 0.01 309762.0 43200.0 0.9 0.6419 0.7136 1001030 SPBio_000435 Cc1onc(c1c2ccc(cc2)S(=O)(=O)N)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F18 compound treatment 298667.0 36700.0 0.74 277853.0 11300.0 0.23 0.6926 0.8869 1048361 SPBio_000436 c1ccc2c(c1)[nH]c3cnccc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F19 compound treatment 2490.0 -259000.0 -5.26 2695.0 -264000.0 -5.5 -7.6065 -0.9998 3198314 SPBio_000437 CCC1OC(=O)[C@H](C)C(=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(OC)C3(CCCn4cnc(c4)c5cccnc5)C[C@@H](C)C(=O)[C@H](C)[C@H]6N(C3)C(=O)O[C@@]61C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F20 compound treatment 241760.0 -20200.0 -0.41 265582.0 -1010.0 -0.02 -0.3039 -0.7425 2069231 SPBio_000438 CC(=CCc1cc(ccc1O)C(=O)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F21 compound treatment 254050.0 -7880.0 -0.16 254365.0 -12200.0 -0.25 -0.293 -0.9747 1002855 SPBio_000439 CCC(C(=O)O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F22 compound treatment 241508.0 -20400.0 -0.41 230592.0 -36000.0 -0.75 -0.823 -0.9608 819 SPBio_000440 CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F23 mock treatment 254739.0 -7190.0 -0.15 245552.0 -21000.0 -0.44 -0.4129 -0.8941 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 F24 mock treatment 264847.0 2920.0 0.06 252960.0 -13600.0 -0.28 -0.1589 -0.5479 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G01 mock treatment 260103.0 -1820.0 -0.04 263834.0 -2760.0 -0.06 -0.0667 -0.9773 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G02 mock treatment 290703.0 28800.0 0.58 254949.0 -11600.0 -0.24 0.241 0.3815 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G03 compound treatment 260425.0 -1500.0 -0.03 259405.0 -7190.0 -0.15 -0.1274 -0.8338 2060058 SPBio_000441 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G04 compound treatment 178283.0 -83600.0 -1.7 2923.0 -264000.0 -5.49 -5.0832 -0.8842 1057125 SPBio_000442 CC(C)(C=C)c1c2OC(C)(C)C=Cc2c(O)c3c(=O)c4ccc(O)c(O)c4oc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G05 compound treatment 269766.0 7840.0 0.16 280962.0 14400.0 0.3 0.3241 0.9561 3173478 SPBio_000443 C[C@H]1C(=O)CCC2[C@]1(C)CCC3[C@@]2(C)CC[C@@]4(C)C5CC(C)(C)CC[C@]5(C)CC[C@]34C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G06 compound treatment 110627.0 -151000.0 -3.07 125057.0 -142000.0 -2.95 -4.2538 -0.9998 3173115 SPBio_000444 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@]61CCC(C)CN6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G07 compound treatment 278022.0 16100.0 0.33 281232.0 14600.0 0.31 0.4464 0.9994 3054135 SPBio_000445 CC(=O)O[C@H]1CC[C@@]2(C)C(CC[C@]3(C)C2CC=C4C5CC(C)(C)CC[C@]5(C)CC[C@]43C)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G08 compound treatment 261680.0 -246.0 0.0 309567.0 43000.0 0.9 0.6296 0.7032 2060429 SPBio_000446 COC1CC(O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)C(CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)OC(C)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G09 compound treatment 298395.0 36500.0 0.74 262576.0 -4010.0 -0.08 0.4636 0.6231 2060065 SPBio_000447 COC[C@@]12CN(C=O)C3[C@@H]4[C@H](OC)C2[C@]3(C5CC6(O)C(OC(=O)c7ccccc7)C5C4(OC(=O)C)C(O)C6OC)[C@H](C[C@H]1O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G10 compound treatment 279533.0 17600.0 0.36 312823.0 46200.0 0.96 0.9335 0.9088 1082254 SPBio_000448 OC(=O)CCNC(=O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G11 compound treatment 251652.0 -10300.0 -0.21 287976.0 21400.0 0.45 0.1678 0.3411 2060068 SPBio_000449 COC1C(O)C(O[C@H]2CC[C@]3(C=O)C4[C@@H](C[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)OC(=O)C)OC(C)C1OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G12 compound treatment 2539.0 -259000.0 -5.26 2677.0 -264000.0 -5.5 -7.6061 -0.9998 1001284 SPBio_000450 CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCC6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCC7C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G13 compound treatment 277593.0 15700.0 0.32 264577.0 -2010.0 -0.04 0.1949 0.6084 3174249 SPBio_000451 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G14 compound treatment 188691.0 -73200.0 -1.48 195049.0 -71500.0 -1.49 -2.1037 -1.0 2069274 SPBio_000452 CC(O)c1c(C)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5CCC(=O)O)c(CCC(=O)O)c4C)c(C)c3C(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G15 compound treatment 245836.0 -16100.0 -0.33 282114.0 15500.0 0.32 -0.002 -0.0043 2060088 SPBio_000453 COc1cc2ccc(=O)oc2c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G16 compound treatment 2068.0 -260000.0 -5.27 2690.0 -264000.0 -5.5 -7.6126 -0.9998 840 SPBio_000454 CCOc1ccc2ccccc2c1NC(=O)[C@H]3[C@H]4SC(C)(C)C(N4C3=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G17 compound treatment 278117.0 16200.0 0.33 286641.0 20100.0 0.42 0.5275 0.9929 2060292 SPBio_000455 CC1(C)[C@H](O)C[C@H](O)[C@@]2(C)C1C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G18 compound treatment 257221.0 -4700.0 -0.1 316941.0 50400.0 1.05 0.6743 0.6402 1041649 SPBio_000456 CC(C)c1ccc(C)c(C(=O)O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G19 compound treatment 267772.0 5850.0 0.12 253371.0 -13200.0 -0.28 -0.1109 -0.37 3472730 SPBio_000457 CC12CCC3C(CC=C4CC(O)CCC34C)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G20 compound treatment 195403.0 -66500.0 -1.35 251676.0 -14900.0 -0.31 -1.1733 -0.8478 1001523 SPBio_000458 Nc1ccc(C(=O)Oc2ccccc2)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G21 compound treatment 243120.0 -18800.0 -0.38 265797.0 -794.0 -0.02 -0.2813 -0.7371 3054130 SPBio_000459 CC(CCC=C(C)C)[C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)C4(C)CC[C@H](OC(=O)C)C(C)(C)C4CC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G22 compound treatment 225093.0 -36800.0 -0.75 247932.0 -18700.0 -0.39 -0.8029 -0.9537 2060420 SPBio_000460 CC(=O)O[C@@H]1CC2C(C)(C)[C@@H](O)CCC2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4C13C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G23 mock treatment 254300.0 -7630.0 -0.15 294340.0 27700.0 0.58 0.2995 0.5004 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 G24 mock treatment 247242.0 -14700.0 -0.3 259627.0 -6960.0 -0.15 -0.3131 -0.9454 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H01 mock treatment 260275.0 -1650.0 -0.03 253592.0 -13000.0 -0.27 -0.2152 -0.7885 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H02 mock treatment 310628.0 48700.0 0.99 300615.0 34000.0 0.71 1.1994 0.9868 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H03 compound treatment 301355.0 39400.0 0.8 266877.0 286.0 0.01 0.5694 0.7124 1235 SPBio_000461 CCOC(=O)CCCCCCCCCCCCC1CCC=C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H04 compound treatment 340816.0 78900.0 1.6 315963.0 49400.0 1.03 1.8582 0.9772 2565 SPBio_000462 COC1=CC(=O)OC1(O)C(=C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H05 compound treatment 280897.0 19000.0 0.38 280056.0 13500.0 0.28 0.4703 0.988 1384 SPBio_000463 COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H06 compound treatment 293208.0 31300.0 0.63 264244.0 -2350.0 -0.05 0.4139 0.6507 2060149 SPBio_000464 Cc1cc(O)c2C(=O)c3c(O)cccc3Cc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H07 compound treatment 318742.0 56800.0 1.15 311035.0 44400.0 0.93 1.4692 0.9941 1044852 SPBio_000465 OC(=O)c1cc2cc(Cl)ccc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H08 compound treatment 277805.0 15900.0 0.32 320803.0 54200.0 1.13 1.0262 0.8739 715 SPBio_000466 COc1c2ccoc2c(OC)c3oc(C)cc(=O)c13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H09 compound treatment 150713.0 -111000.0 -2.25 18006.0 -249000.0 -5.18 -5.2562 -0.9306 3078458 SPBio_000467 CCCCCC/C=C\CCCCCCCc1cccc(O)c1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H10 compound treatment 287650.0 25700.0 0.52 335508.0 68900.0 1.44 1.384 0.906 886 SPBio_000468 O[C@@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H11 compound treatment 267010.0 5080.0 0.1 306765.0 40200.0 0.84 0.6647 0.7882 710 SPBio_000469 CC(=O)OCC1=C(N2C(SC1)[C@H](NC(=O)CCCC(N)C(=O)O)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H12 compound treatment 190965.0 -71000.0 -1.44 228471.0 -38100.0 -0.79 -1.5788 -0.9608 1737132 SPBio_000470 COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c2c34)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H13 compound treatment 257493.0 -4430.0 -0.09 279258.0 12700.0 0.26 0.1231 0.4414 1001994 SPBio_000471 C[C@@H](N)[C@@H](O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H14 compound treatment 260308.0 -1620.0 -0.03 280758.0 14200.0 0.3 0.1855 0.6247 4895 SPBio_000472 C[n+]1cccc(c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H15 compound treatment 242893.0 -19000.0 -0.39 266125.0 -466.0 -0.01 -0.2797 -0.7247 1004889 SPBio_000473 CC(=O)Nc1cccc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H16 compound treatment 68136.0 -194000.0 -3.93 105198.0 -161000.0 -3.36 -5.1555 -0.997 2060141 SPBio_000474 COC1=CC(=O)C(=CC1=O)C(C=C)c2ccc(OC)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H17 compound treatment 2653.0 -259000.0 -5.26 2526.0 -264000.0 -5.5 -7.6067 -0.9997 954 SPBio_000475 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H18 compound treatment 269003.0 7080.0 0.14 262752.0 -3840.0 -0.08 0.0449 0.2734 1539748 SPBio_000476 COc1ccccc1c2coc3cc(O)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H19 compound treatment 257089.0 -4840.0 -0.1 257244.0 -9350.0 -0.19 -0.207 -0.9496 906 SPBio_000477 N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H20 compound treatment 245767.0 -16200.0 -0.33 274566.0 7980.0 0.17 -0.1142 -0.3108 1010377 SPBio_000478 Oc1ccc2C3c4cc(O)c(O)cc4CC3(O)COc2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H21 compound treatment 265599.0 3670.0 0.07 261159.0 -5430.0 -0.11 -0.0274 -0.202 2069291 SPBio_000479 COc1cc(cc(OC)c1OC)[C@H]2[C@H]3[C@H](COC3=O)[C@@H](O)c4cc5OCOc5cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H22 compound treatment 251476.0 -10400.0 -0.21 275641.0 9050.0 0.19 -0.0165 -0.0581 3055310 SPBio_000480 COc1c(O)cc2C(=O)O[C@H]3[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]3c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H23 mock treatment 260354.0 -1570.0 -0.03 257973.0 -8620.0 -0.18 -0.1495 -0.8198 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 H24 mock treatment 267007.0 5080.0 0.1 260430.0 -6160.0 -0.13 -0.0179 -0.1089 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I01 mock treatment 226123.0 -35800.0 -0.73 278566.0 12000.0 0.25 -0.3368 -0.4389 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I02 mock treatment 279932.0 18000.0 0.37 277136.0 10500.0 0.22 0.4135 0.9705 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I03 compound treatment 253941.0 -7980.0 -0.16 259488.0 -7100.0 -0.15 -0.2191 -0.999 3173612 SPBio_000481 CC(=O)OC1CC2(O)C3CCC4CC(CC[C@]4(C)C3CC[C@]2(C)C1C5=CC(=O)OC5)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I04 compound treatment 289256.0 27300.0 0.55 269407.0 2820.0 0.06 0.4333 0.7776 2060151 SPBio_000482 COC(=O)[C@@H]1OC(=O)C2OC23[C@@]1(C)CCC4[C@@]5(C)[C@H](C[C@@H](OC(=O)C)C(C)(C)C5C[C@H](O)[C@]43C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I05 compound treatment 267062.0 5140.0 0.1 300323.0 33700.0 0.7 0.5705 0.8031 2060096 SPBio_000483 CC(=O)O[C@@H]1CC(=O)[C@@]2(C)C(CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I06 compound treatment 277093.0 15200.0 0.31 286200.0 19600.0 0.41 0.5063 0.9902 2060396 SPBio_000484 OC[C@H]1O[C@@H](Oc2ccc(C(=O)/C=C/c3ccccc3)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I07 compound treatment 285095.0 23200.0 0.47 298883.0 32300.0 0.67 0.8078 0.9846 2060098 SPBio_000485 C[C@@]12CCC3C(CC[C@H]4C[C@@H](Cl)CC[C@@]43C)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I08 compound treatment 235056.0 -26900.0 -0.54 273967.0 7380.0 0.15 -0.2765 -0.4886 2060410 SPBio_000486 CC1(C)[C@H](O)CC(=O)[C@@]2(C)C1C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I09 compound treatment 236806.0 -25100.0 -0.51 273667.0 7080.0 0.15 -0.2559 -0.4826 2060114 SPBio_000487 COc1c2OCOc2cc3cc[n+](C)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I10 compound treatment 257158.0 -4770.0 -0.1 295417.0 28800.0 0.6 0.3563 0.5858 1503 SPBio_000488 Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I11 compound treatment 266330.0 4400.0 0.09 274365.0 7770.0 0.16 0.1777 0.9606 2060122 SPBio_000489 CC1(C)Oc2cc3oc(=O)ccc3cc2C=C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I12 compound treatment 248093.0 -13800.0 -0.28 234659.0 -31900.0 -0.67 -0.6687 -0.9263 3077356 SPBio_000490 COc1cc(cc(OC)c1O)[C@H]2C3C(COC3=O)[C@H](O)c4cc5OCOc5cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I13 compound treatment 13057.0 -249000.0 -5.05 10663.0 -256000.0 -5.33 -7.3377 -0.9996 2060124 SPBio_000491 COC(=O)[C@@]1(C)CCC[C@@]2(C)C1CCc3c(C(C)C)c(O)ccc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I14 compound treatment 252112.0 -9810.0 -0.2 328447.0 61900.0 1.29 0.7705 0.5909 1837 SPBio_000492 CS(=O)(=O)c1ccc(cc1)C2=C(C(=O)OC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I15 compound treatment 268806.0 6880.0 0.14 298326.0 31700.0 0.66 0.5661 0.8378 2060128 SPBio_000493 CO[C@@H]1C(OC(=O)C(C)C)[C@@]2(C)[C@@H](OC(=O)/C(=C(\OC)/C(C)C)/C2[C@@]34OC5(C)O[C@]14[C@]6(C)[C@@H](CC(=O)OC)C7(C)CC6(O5)[C@](OC)(C7OC(=O)C)[C@H]3OC)c8ccoc8 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I16 compound treatment 247248.0 -14700.0 -0.3 306925.0 40300.0 0.84 0.3838 0.4305 750 SPBio_000494 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1OC2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](NC(=N)N)[C@@H](O)[C@@H]3NC(=N)N)O[C@@H](C)[C@]2(O)C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I17 compound treatment 262804.0 878.0 0.02 287873.0 21300.0 0.44 0.3261 0.7349 2060146 SPBio_000495 C[C@@]12CCC(=O)C=C2CCc3ccc(O)cc31 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I18 compound treatment 293111.0 31200.0 0.63 308421.0 41800.0 0.87 1.0632 0.9876 1358 SPBio_000496 CN(CCCl)CCCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I19 compound treatment 250678.0 -11200.0 -0.23 265446.0 -1140.0 -0.02 -0.1781 -0.7768 2060157 SPBio_000497 CC(=O)C1CCC2C3CCC4C[C@H](O)CCC4(C)C3C[C@H](O)C12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I20 compound treatment 241792.0 -20100.0 -0.41 270525.0 3930.0 0.08 -0.2307 -0.5541 1913604 SPBio_000498 OC(=O)CCCN1C(=O)c2cccc3cccc(C1=O)c23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I21 compound treatment 258518.0 -3410.0 -0.07 306918.0 40300.0 0.84 0.5452 0.6468 2060159 SPBio_000499 COC(=O)[C@@H]1OC(=O)C2OC23[C@@]1(C)CCC4[C@@]5(C)CCC(=O)C(C)(C)C5C[C@@H](OC(=O)C)[C@]43C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I22 compound treatment 250685.0 -11200.0 -0.23 259120.0 -7470.0 -0.16 -0.2712 -0.9827 3055336 SPBio_000500 Oc1ccc2sc(=O)oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I23 mock treatment 258025.0 -3900.0 -0.08 276403.0 9810.0 0.2 0.0886 0.4044 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 I24 mock treatment 236561.0 -25400.0 -0.51 263297.0 -3290.0 -0.07 -0.4121 -0.7944 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J01 mock treatment 250950.0 -11000.0 -0.22 275822.0 9230.0 0.19 -0.0214 -0.0726 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J02 mock treatment 263299.0 1370.0 0.03 309255.0 42700.0 0.89 0.6482 0.7289 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J03 compound treatment 288195.0 26300.0 0.53 274896.0 8310.0 0.17 0.4989 0.891 3198315 SPBio_000501 COc1ccc(cc1F)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J04 compound treatment 279698.0 17800.0 0.36 310604.0 44000.0 0.92 0.9031 0.9167 989 SPBio_000502 NC(=N)NCCCCNC(=N)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J05 compound treatment 265950.0 4020.0 0.08 330586.0 64000.0 1.33 1.0004 0.749 1439 SPBio_000503 CSCCC(N)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J06 compound treatment 211699.0 -50200.0 -1.02 287680.0 21100.0 0.44 -0.4093 -0.3691 2060167 SPBio_000504 COC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J07 compound treatment 4444.0 -257000.0 -5.22 4684.0 -262000.0 -5.46 -7.5492 -0.9998 3060196 SPBio_000505 COc1c(CN2CC[C@@H]3CCCN[C@@H]3C2)c(F)cc4c(=O)c(cn(C5CC5)c14)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J08 compound treatment 227998.0 -33900.0 -0.69 190157.0 -76400.0 -1.59 -1.6123 -0.9295 926 SPBio_000506 Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J09 compound treatment 286779.0 24900.0 0.5 296941.0 30400.0 0.63 0.8034 0.9937 1449108 SPBio_000507 Cc1ccc2c(Cl)cc(Cl)c(O)c2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J10 compound treatment 293536.0 31600.0 0.64 316471.0 49900.0 1.04 1.1879 0.973 3055321 SPBio_000508 CC(CCC(=O)O)[C@H]1CCC2C3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J11 compound treatment 294270.0 32300.0 0.66 278099.0 11500.0 0.24 0.6332 0.9069 913 SPBio_000509 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)O)n2ccc(=O)[nH]c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J12 compound treatment 274805.0 12900.0 0.26 317026.0 50400.0 1.05 0.9276 0.8568 1055132 SPBio_000510 COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J13 compound treatment 295153.0 33200.0 0.67 334973.0 68400.0 1.42 1.4837 0.9415 3480078 SPBio_000511 CC(C)N(CCC(c1ccccc1)c2cc(C)ccc2O)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J14 compound treatment 257393.0 -4530.0 -0.09 301799.0 35200.0 0.73 0.4537 0.6137 2069273 SPBio_000512 N[C@H]1[C@@H](O)O[C@H](CO)[C@H](O)[C@@H]1O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J15 compound treatment 258149.0 -3780.0 -0.08 301450.0 34900.0 0.73 0.4594 0.6291 2060469 SPBio_000513 C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)C)C3(C)C[C@H](O)C2C4(C)C=CC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J16 compound treatment 284422.0 22500.0 0.46 212241.0 -54300.0 -1.13 -0.4781 -0.3917 3177314 SPBio_000514 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CCC=C4C(=O)c3c(O)c2C=C1)[C@@](C/C=C(\C)/C(=O)O)(OC5(C)C)C(=O)O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J17 compound treatment 280826.0 18900.0 0.38 298591.0 32000.0 0.67 0.7423 0.9654 2069250 SPBio_000515 OCC(O)CC(O)CCCCCCCCCCCC#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J18 compound treatment 258049.0 -3880.0 -0.08 264594.0 -2000.0 -0.04 -0.085 -0.9558 1084508 SPBio_000516 COc1ccc2cc3-c4cc(OC)c(OC)cc4CC[n+]3cc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J19 compound treatment 263386.0 1460.0 0.03 261051.0 -5540.0 -0.12 -0.0607 -0.5092 3198316 SPBio_000517 C[C@@H]1O[C@@H](OC[C@H]2OC(Oc3c(oc4cc(OCCO)cc(O)c4c3=O)c5ccc(OCCO)c(OCCO)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J20 compound treatment 218048.0 -43900.0 -0.89 271622.0 5030.0 0.1 -0.5549 -0.6195 2069242 SPBio_000518 CC(=CCc1cc(cc(CC=C(C)C)c1O)C(=O)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J21 compound treatment 192886.0 -69000.0 -1.4 209724.0 -56900.0 -1.18 -1.8274 -0.9966 702 SPBio_000519 CCCCCC(=O)O[C@@]1(CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J22 compound treatment 263105.0 1180.0 0.02 215374.0 -51200.0 -1.07 -0.7376 -0.6911 3172733 SPBio_000520 Cc1c(C(=O)O)c(O)cc2C(=O)c3c(O)c(O)c(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c3C(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J23 mock treatment 273293.0 11400.0 0.23 254936.0 -11700.0 -0.24 -0.0087 -0.0261 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 J24 mock treatment 226164.0 -35800.0 -0.72 260682.0 -5910.0 -0.12 -0.5997 -0.8155 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K01 mock treatment 261068.0 -858.0 -0.02 270258.0 3670.0 0.08 0.0417 0.5325 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K02 mock treatment 290323.0 28400.0 0.58 281196.0 14600.0 0.3 0.6222 0.9556 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K03 compound treatment 260092.0 -1830.0 -0.04 281269.0 14700.0 0.31 0.1899 0.6166 2060184 SPBio_000521 CC1CCc2c(O)c3c(=O)cc(C)oc3cc2OC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K04 compound treatment 292237.0 30300.0 0.61 284789.0 18200.0 0.38 0.7026 0.9731 3173993 SPBio_000522 O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K05 compound treatment 242119.0 -19800.0 -0.4 280667.0 14100.0 0.29 -0.0766 -0.154 2060185 SPBio_000523 COc1ccc2[C@@H]3COc4cc(OC)ccc4[C@@H]3Oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K06 compound treatment 119442.0 -142000.0 -2.89 147930.0 -119000.0 -2.47 -3.7905 -0.997 2069260 SPBio_000524 CC[C@@]1(O)C[C@H](O)c2c(O)c3C(=O)c4c(O)ccc(O)c4C(=O)c3cc2[C@H]1C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K07 compound treatment 259290.0 -2640.0 -0.05 287965.0 21400.0 0.45 0.2771 0.6178 2060186 SPBio_000525 CC(=O)OC1CCC2(C3CCC4(C)C(CCC54OC2=O)C6=CC(=O)OC6)C(O)(CCC35)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K08 compound treatment 280050.0 18100.0 0.37 303234.0 36600.0 0.76 0.7996 0.9438 2060406 SPBio_000526 COc1ccccc1/C=C\C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K09 compound treatment 263299.0 1370.0 0.03 274125.0 7530.0 0.16 0.1307 0.8197 2060446 SPBio_000527 CC1(C)[C@@H](O)C=C[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K10 compound treatment 255612.0 -6310.0 -0.13 279374.0 12800.0 0.27 0.0978 0.331 3174367 SPBio_000528 NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K11 compound treatment 242482.0 -19400.0 -0.39 297243.0 30700.0 0.64 0.1728 0.2303 2060390 SPBio_000529 CC(=O)O[C@H]1CC[C@@]2(C)C(C[C@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)C(OC(=O)C=C43)c5ccoc5)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K12 compound treatment 249938.0 -12000.0 -0.24 295908.0 29300.0 0.61 0.26 0.3956 2060082 SPBio_000530 COC(=O)c1cc(OC)c(=O)c2c(OC)c(OC)ccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K13 compound treatment 255277.0 -6650.0 -0.13 274205.0 7610.0 0.16 0.0169 0.081 1111461 SPBio_000531 CC(=CCOc1c2occc2cc3ccc(=O)oc13)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K14 compound treatment 287141.0 25200.0 0.51 266106.0 -485.0 -0.01 0.3543 0.693 1054271 SPBio_000532 COc1ccc(cc1O)c2cc(=O)c3c(O)c(OC)c(OC)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K15 compound treatment 265331.0 3410.0 0.07 292750.0 26200.0 0.54 0.4342 0.7904 3174000 SPBio_000533 C[C@H]1[C@H]2[C@H](CC3C4CC[C@@H]5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K16 compound treatment 234673.0 -27300.0 -0.55 242630.0 -24000.0 -0.5 -0.7436 -0.9987 1527 SPBio_000534 COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5ccc4C(=O)[C@H]3c2cc1OC)C(=C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K17 compound treatment 263803.0 1880.0 0.04 269026.0 2440.0 0.05 0.0628 0.99 3173615 SPBio_000535 CCC(CCC(C)[C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K18 compound treatment 258598.0 -3330.0 -0.07 305818.0 39200.0 0.82 0.5302 0.6465 1001 SPBio_000536 CN(C)CCOC(=O)COc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K19 compound treatment 271762.0 9840.0 0.2 293806.0 27200.0 0.57 0.5419 0.9017 2060206 SPBio_000537 CCC(CCC(C)C1CCC2C3CC=C4C[C@H](CC[C@]4(C)C3CC[C@]12C)OC(=O)C)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K20 compound treatment 262393.0 467.0 0.01 302801.0 36200.0 0.75 0.5401 0.7159 1065857 SPBio_000538 NC(CNC(=O)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K21 compound treatment 251432.0 -10500.0 -0.21 276315.0 9720.0 0.2 -0.0072 -0.0244 2069265 SPBio_000539 C[C@@]12CCC3C(CC[C@H]4CC(=O)CC[C@@]43C)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K22 compound treatment 3075.0 -259000.0 -5.25 2862.0 -264000.0 -5.49 -7.5957 -0.9997 981 SPBio_000540 CCCCCCCCCCCCCCCC[n+]1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K23 mock treatment 265705.0 3780.0 0.08 247958.0 -18600.0 -0.39 -0.2203 -0.5568 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 K24 mock treatment 243808.0 -18100.0 -0.37 267667.0 1080.0 0.02 -0.2439 -0.6627 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L01 mock treatment 293452.0 31500.0 0.64 213563.0 -53000.0 -1.1 -0.3292 -0.258 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L02 mock treatment 292135.0 30200.0 0.61 301587.0 35000.0 0.73 0.9486 0.9962 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L03 compound treatment 276122.0 14200.0 0.29 336333.0 69700.0 1.45 1.2309 0.831 1009258 SPBio_000541 O=C1NC(=O)C(=O)C(=O)N1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L04 compound treatment 343228.0 81300.0 1.65 318459.0 51900.0 1.08 1.9296 0.979 2069264 SPBio_000542 C[C@@]12CCC3C(CC[C@H]4C[C@@H](O)CC[C@@]43C)C2CC[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L05 compound treatment 265417.0 3490.0 0.07 302161.0 35600.0 0.74 0.574 0.7711 857 SPBio_000543 O=C(OCc1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L06 compound treatment 326080.0 64200.0 1.3 295590.0 29000.0 0.6 1.3468 0.9392 1009367 SPBio_000544 OC1=CC2=C3c4ccc(O)c(O)c4OCC3(O)CC2=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L07 compound treatment 280267.0 18300.0 0.37 321388.0 54800.0 1.14 1.0701 0.8913 1021 SPBio_000545 CO[C@@H]1[C@@H](O)[C@H](C)O[C@@H](O[C@H]2CC[C@@]3(C)[C@H](CCC4C3CC[C@]5(C)C(CC[C@]45O)C6=CC(=O)OC6)C2)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L08 compound treatment 272262.0 10300.0 0.21 297863.0 31300.0 0.65 0.6088 0.8897 991 SPBio_000546 CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L09 compound treatment 302336.0 40400.0 0.82 313650.0 47100.0 0.98 1.2725 0.996 1147 SPBio_000547 COc1c2ccoc2cc3oc(=O)ccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L10 compound treatment 288933.0 27000.0 0.55 311733.0 45100.0 0.94 1.0521 0.9669 1000126 SPBio_000548 C[C@H](CCC(=O)O)[C@H]1CCC2C3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L11 compound treatment 303856.0 41900.0 0.85 326415.0 59800.0 1.25 1.4824 0.9826 2060361 SPBio_000549 C/C=C(/C)\C(=O)O[C@@H]1[C@H](OC(=O)C)[C@]2(CO)[C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(=O)O)[C@](C)(CO)C5CC[C@]43C)C2CC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L12 compound treatment 273369.0 11400.0 0.23 326790.0 60200.0 1.25 1.0508 0.8239 2060057 SPBio_000550 COC(=O)C[C@H]1C(C)(C)[C@@H](OC(=O)C)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L13 compound treatment 303314.0 41400.0 0.84 289871.0 23300.0 0.48 0.9362 0.9661 2060456 SPBio_000551 C[C@@H]1CC(Cl)CC[C@H]1C(=O)OC(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L14 compound treatment 271005.0 9080.0 0.18 319588.0 53000.0 1.1 0.9109 0.8138 2060413 SPBio_000552 CC(C)CCCC(C)[C@H]1CCC2C3CC[C@H]4CC(=O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L15 compound treatment 264300.0 2370.0 0.05 243356.0 -23200.0 -0.48 -0.3082 -0.6337 2060378 SPBio_000553 Oc1nc2cc(Cl)c(Cl)cc2nc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L16 compound treatment 289696.0 27800.0 0.56 308956.0 42400.0 0.88 1.0222 0.9764 1011559 SPBio_000554 Cc1cc(=O)oc2cc(O)c(O)cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L17 compound treatment 287254.0 25300.0 0.51 300238.0 33600.0 0.7 0.8587 0.9883 3055475 SPBio_000555 COc1ccc(/C=C/C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L18 compound treatment 277557.0 15600.0 0.32 297359.0 30800.0 0.64 0.6773 0.9472 2060366 SPBio_000556 CC1(C)C=CC(=O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L19 compound treatment 239346.0 -22600.0 -0.46 295814.0 29200.0 0.61 0.1068 0.1402 1187 SPBio_000557 C[C@@]12CCC3C(CCc4cc(OS(=O)(=O)O)ccc34)C2CC[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L20 compound treatment 2968.0 -259000.0 -5.25 2381.0 -264000.0 -5.5 -7.6043 -0.9997 2060045 SPBio_000558 CC(=C)/C=C\1/C=CC(=O)C(=C1)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L21 compound treatment 249184.0 -12700.0 -0.26 261683.0 -4910.0 -0.1 -0.255 -0.9177 1052338 SPBio_000559 COc1cc2C(C)NCCc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L22 compound treatment 263574.0 1650.0 0.03 233766.0 -32800.0 -0.68 -0.4599 -0.6718 3172727 SPBio_000560 CC(=C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L23 mock treatment 278492.0 16600.0 0.34 244450.0 -22100.0 -0.46 -0.0887 -0.1554 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 L24 mock treatment 247089.0 -14800.0 -0.3 262907.0 -3680.0 -0.08 -0.267 -0.86 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M01 mock treatment 271472.0 9550.0 0.19 248731.0 -17900.0 -0.37 -0.1263 -0.301 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M02 mock treatment 314579.0 52700.0 1.07 315296.0 48700.0 1.01 1.4723 0.9997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M03 compound treatment 273566.0 11600.0 0.24 262036.0 -4550.0 -0.09 0.0998 0.3922 2060155 SPBio_000561 COC(=O)[C@@H]1OC(=O)C2OC23[C@@]1(C)CCC4[C@@]5(C)[C@H](C[C@@H](OC(=O)C)C(C)(C)C5C[C@@H](O)[C@]43C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M04 compound treatment 298079.0 36200.0 0.73 272066.0 5480.0 0.11 0.5989 0.8074 2060215 SPBio_000562 CC1(C)C2C=C[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)[C@@]2(C)C=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M05 compound treatment 9995.0 -252000.0 -5.11 10641.0 -256000.0 -5.33 -7.3819 -0.9998 1010376 SPBio_000563 Oc1ccc2C3c4cc(O)c(O)cc4CC3(O)COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M06 compound treatment 301201.0 39300.0 0.8 283071.0 16500.0 0.34 0.8058 0.9293 3173759 SPBio_000564 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(OC4O[C@@H]5COC(C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M07 compound treatment 284438.0 22500.0 0.46 340551.0 74000.0 1.54 1.4122 0.8788 1326 SPBio_000565 CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M08 compound treatment 2475.0 -259000.0 -5.26 5266.0 -261000.0 -5.44 -7.5689 -0.9999 1015281 SPBio_000566 COc1cc(O)c(C(=O)C)c(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M09 compound treatment 276446.0 14500.0 0.29 293385.0 26800.0 0.56 0.6029 0.9553 1570 SPBio_000567 CCCC(C)C1(CC=C)C(=O)NC(=NC1=O)S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M10 compound treatment 246610.0 -15300.0 -0.31 154277.0 -112000.0 -2.34 -1.8741 -0.794 1473 SPBio_000568 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M11 compound treatment 249208.0 -12700.0 -0.26 263372.0 -3220.0 -0.07 -0.2297 -0.8623 2060408 SPBio_000569 COC(=O)C[C@H]1C(C)(C)[C@H](C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M12 compound treatment 291138.0 29200.0 0.59 264460.0 -2130.0 -0.04 0.3874 0.6523 2069338 SPBio_000570 CC(=O)O[C@@H]1Cc2c(OC(=O)C)cc(OC(=O)C)cc2O[C@@H]1c3ccc(OC(=O)C)c(OC(=O)C)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M13 compound treatment 267221.0 5300.0 0.11 303721.0 37100.0 0.77 0.6229 0.7976 1050335 SPBio_000571 COc1cc(OC)c(C=O)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M14 compound treatment 230329.0 -31600.0 -0.64 212176.0 -54400.0 -1.13 -1.2545 -0.9635 1950 SPBio_000572 Oc1cc2oc(cc(=O)c2c(O)c1O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M15 compound treatment 277113.0 15200.0 0.31 277381.0 10800.0 0.22 0.3767 0.988 3198311 SPBio_000573 Cc1cc(O)c(C=O)c2Oc3c(C)c(C(=O)O)c(O)c(COC(=O)/C=C/C(=O)O)c3OC(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M16 compound treatment 105248.0 -157000.0 -3.18 89491.0 -177000.0 -3.69 -4.8549 -0.9972 832189 SPBio_000574 CC(=O)CC(=O)CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M17 compound treatment 6447.0 -255000.0 -5.18 2758.0 -264000.0 -5.5 -7.5489 -0.9996 1597 SPBio_000575 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CC6C=C4C(=O)c3c(O)c2C=C1)C(C/C=C(/C)\C(=O)O)(OC5(C)C)C6=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M18 compound treatment 248012.0 -13900.0 -0.28 290365.0 23800.0 0.5 0.1508 0.2645 780 SPBio_000576 CC(C)NNC(=O)c1ccncc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M19 compound treatment 2470.0 -259000.0 -5.26 34445.0 -232000.0 -4.84 -7.1391 -0.9991 2060116 SPBio_000577 CCC(=O)OC1[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@](C)([C@@H](CC(=O)OC)C1(C)C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M20 compound treatment 263723.0 1800.0 0.04 292862.0 26300.0 0.55 0.4128 0.7525 3173091 SPBio_000578 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)C(O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3OC4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M21 compound treatment 246130.0 -15800.0 -0.32 260145.0 -6450.0 -0.13 -0.3214 -0.9255 1071570 SPBio_000579 CCOC(=O)c1c(C)cc(O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M22 compound treatment 251154.0 -10800.0 -0.22 325720.0 59100.0 1.23 0.7166 0.5728 3172862 SPBio_000580 O=c1cccc2C3CNC[C@@H](C3)Cn21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M23 mock treatment 242061.0 -19900.0 -0.4 278529.0 11900.0 0.25 -0.1089 -0.2301 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 M24 mock treatment 235773.0 -26200.0 -0.53 261053.0 -5540.0 -0.12 -0.4565 -0.8413 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N01 mock treatment 281353.0 19400.0 0.39 259130.0 -7460.0 -0.16 0.1686 0.3982 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N02 mock treatment 303477.0 41600.0 0.84 331480.0 64900.0 1.35 1.5515 0.9741 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N03 compound treatment 3696.0 -258000.0 -5.24 3505.0 -263000.0 -5.48 -7.5773 -0.9997 3471725 SPBio_000581 CC1(C)SC2C(NC(=O)C(N=C)c3ccccc3)C(=O)N2C1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N04 compound treatment 8982.0 -253000.0 -5.13 8389.0 -258000.0 -5.38 -7.4296 -0.9997 3173106 SPBio_000582 COC(=O)c1c(C)c2Oc3c(Cl)c(O)c(Cl)c(C)c3C(=O)Oc2c(C)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N05 compound treatment 309861.0 47900.0 0.97 359238.0 92600.0 1.93 2.052 0.9496 3474304 SPBio_000583 COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N06 compound treatment 305335.0 43400.0 0.88 307166.0 40600.0 0.85 1.22 0.9998 2069253 SPBio_000584 CC(C)/C(=C/1\C2[C@@]34OC5(C)O[C@@]4([C@H](O)C(O)[C@@]2(C)[C@@H](OC1=O)c6ccoc6)[C@]7(C)[C@@H](CC(=O)O)C8(C)CC7(O5)[C@](O)(C8O)[C@H]3O)/O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N07 compound treatment 163074.0 -98900.0 -2.0 154581.0 -112000.0 -2.33 -3.0671 -0.9971 1001621 SPBio_000585 Oc1cc(cc(O)c1O)C(=O)Oc2cc(cc(O)c2O)C(=O)OC[C@H]3O[C@H](OC(=O)c4cc(O)c(O)c(OC(=O)c5cc(O)c(O)c(O)c5)c4)[C@H](OC(=O)c6cc(O)c(O)c(OC(=O)c7cc(O)c(O)c(O)c7)c6)[C@@H](OC(=O)c8cc(O)c(O)c(OC(=O)c9cc(O)c(O)c(O)c9)c8)[C@@H]3OC(=O)c%10cc(O)c(O)c(OC(=O)c%11cc(O)c(O)c(O)c%11)c%10 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N08 compound treatment 300631.0 38700.0 0.78 330548.0 64000.0 1.33 1.497 0.9681 1101 SPBio_000586 CCCC1O[C@@H]2CC3C4CCC5=CC(=O)C=CC5(C)C4[C@@H](O)CC3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N09 compound treatment 292642.0 30700.0 0.62 331793.0 65200.0 1.36 1.4008 0.9375 789 SPBio_000587 C[N+]1(C)C2CC[C@H]1C[C@H](C2)OC(=O)C(O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N10 compound treatment 2154.0 -260000.0 -5.27 2400.0 -264000.0 -5.5 -7.6157 -0.9998 3173360 SPBio_000588 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4CCCC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N11 compound treatment 4175.0 -258000.0 -5.23 2622.0 -264000.0 -5.5 -7.5834 -0.9997 2060466 SPBio_000589 OC(=O)Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N12 compound treatment 269991.0 8070.0 0.16 221553.0 -45000.0 -0.94 -0.5478 -0.5752 2060311 SPBio_000590 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4CC(=O)CC[C@]4(C)C3C=C[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N13 compound treatment 2375.0 -260000.0 -5.26 2359.0 -264000.0 -5.5 -7.6131 -0.9997 3172984 SPBio_000591 COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N14 compound treatment 215415.0 -46500.0 -0.94 80654.0 -186000.0 -3.87 -3.4058 -0.8543 2060399 SPBio_000592 CC(C)CCCC(C)[C@H]1CCC2C3C[C@@H](O)[C@@]4(O)C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N15 compound treatment 243723.0 -18200.0 -0.37 283795.0 17200.0 0.36 -0.0075 -0.0146 911 SPBio_000593 CCCCCC(C)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N16 compound treatment 2498.0 -259000.0 -5.26 5419.0 -261000.0 -5.44 -7.5663 -0.9999 2060079 SPBio_000594 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CC6C=C4C(=O)c3c(O)c2C=C1)C(C/C=C(/C)\C(=O)O)(OC5(C)C)C6O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N17 compound treatment 265096.0 3170.0 0.06 345103.0 78500.0 1.64 1.202 0.7343 1001451 SPBio_000595 Cc1cc(C)cc(OCC2CNC(=O)O2)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N18 compound treatment 55340.0 -207000.0 -4.19 45364.0 -221000.0 -4.61 -6.2203 -0.9989 1600 SPBio_000596 CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N19 compound treatment 259104.0 -2820.0 -0.06 272024.0 5430.0 0.11 0.0396 0.3121 1470 SPBio_000597 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N20 compound treatment 233451.0 -28500.0 -0.58 249139.0 -17500.0 -0.36 -0.6653 -0.9752 2060071 SPBio_000598 CCOC(=O)c1c(C)cc(O)c(C=O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N21 compound treatment 250438.0 -11500.0 -0.23 258659.0 -7930.0 -0.17 -0.2815 -0.9859 399 SPBio_000599 Nc1nc2ccc(OC(F)(F)F)cc2s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N22 compound treatment 247152.0 -14800.0 -0.3 244808.0 -21800.0 -0.45 -0.5327 -0.9797 3172726 SPBio_000600 C[C@]12C3CCC(O3)[C@]2(C)C(=O)OC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N23 mock treatment 243935.0 -18000.0 -0.36 237391.0 -29200.0 -0.61 -0.688 -0.9701 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 N24 mock treatment 238669.0 -23300.0 -0.47 230448.0 -36100.0 -0.75 -0.8658 -0.9746 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O01 mock treatment 247506.0 -14400.0 -0.29 272425.0 5830.0 0.12 -0.1208 -0.3815 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O02 mock treatment 292350.0 30400.0 0.62 296556.0 30000.0 0.62 0.8776 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O03 compound treatment 273141.0 11200.0 0.23 289819.0 23200.0 0.48 0.5029 0.9407 2060228 SPBio_000601 COC(=O)CC1[C@@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]53O[C@]2(O)[C@@H]([C@H]5OC(=O)C)C(OC(=O)C)C1(C)C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O04 compound treatment 265569.0 3640.0 0.07 284258.0 17700.0 0.37 0.3125 0.8324 1129781 SPBio_000602 COc1ccc(cc1)c2cc(=O)c3c(OC)cc(OC)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O05 compound treatment 278821.0 16900.0 0.34 305681.0 39100.0 0.81 0.818 0.9259 2060178 SPBio_000603 CC12C[C@@H](O)C3C(CCC4CC(O)CCC43C)C2(O)CCC1C5=CC(=O)OC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O06 compound treatment 276741.0 14800.0 0.3 285561.0 19000.0 0.4 0.4918 0.9908 2060451 SPBio_000604 CC(C)(O)CC[C@@H](O)[C@](C)(O)C1CC[C@@]2(O)C3=CC(=O)C4C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O07 compound treatment 252731.0 -9190.0 -0.19 251878.0 -14700.0 -0.31 -0.3485 -0.9716 2060209 SPBio_000605 COc1cc2OCC3Oc4c(C(=O)O)c(O)ccc4C(=O)C3(O)c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O08 compound treatment 303855.0 41900.0 0.85 279995.0 13400.0 0.28 0.7985 0.8925 3174226 SPBio_000606 CC[N+](C)(C)Cc1ccc(Br)cc1.Cc1ccc(cc1)S(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O09 compound treatment 238509.0 -23400.0 -0.47 275262.0 8670.0 0.18 -0.2079 -0.4094 2060130 SPBio_000607 COc1ccc(cc1)[C@@H](C)C(=O)c2ccc(O)cc2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O10 compound treatment 236246.0 -25700.0 -0.52 294537.0 27900.0 0.58 0.0436 0.0558 3263 SPBio_000608 CNC(C)(C)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O11 compound treatment 299717.0 37800.0 0.77 284343.0 17800.0 0.37 0.8032 0.9442 2060064 SPBio_000609 CCC(C)C(=O)OC1[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@](C)([C@@H](CC(=O)OC)C1(C)C)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O12 compound treatment 269689.0 7760.0 0.16 288442.0 21900.0 0.46 0.4332 0.8993 1231 SPBio_000610 CC(C)C[C@H](NC(=O)C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O13 compound treatment 259533.0 -2390.0 -0.05 234027.0 -32600.0 -0.68 -0.514 -0.7557 2060078 SPBio_000611 COc1cc2OC[C@H]3Oc4c(CC=C(C)C)c(O)ccc4C(=O)[C@H]3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O14 compound treatment 284913.0 23000.0 0.47 296238.0 29600.0 0.62 0.7663 0.9904 2060471 SPBio_000612 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H]3C(=CC(=O)C3=C(C)C[C@@H]2O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O15 compound treatment 200490.0 -61400.0 -1.25 168186.0 -98400.0 -2.05 -2.3303 -0.9715 1009294 SPBio_000613 Oc1ccc2C(=O)c3ccccc3C(=O)c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O16 compound treatment 284615.0 22700.0 0.46 274299.0 7710.0 0.16 0.4388 0.9007 3055313 SPBio_000614 CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5C[C@H]6C7=C(CC[C@@]64C)C(=O)OC7)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O17 compound treatment 259428.0 -2500.0 -0.05 259016.0 -7570.0 -0.16 -0.1474 -0.8893 1112402 SPBio_000615 COc1ccc2ccc(=O)oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O18 compound treatment 66621.0 -195000.0 -3.96 26739.0 -240000.0 -5.0 -6.333 -0.9934 2559 SPBio_000616 CC(=O)O[Cd]OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O19 compound treatment 245297.0 -16600.0 -0.34 243592.0 -23000.0 -0.48 -0.5772 -0.9852 1016781 SPBio_000617 OC(=O)c1cc(O)c(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O20 compound treatment 252314.0 -9610.0 -0.19 290313.0 23700.0 0.49 0.2117 0.3984 1120 SPBio_000618 Oc1ccc(cc1[N+](=O)[O-])[As](=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O21 compound treatment 270168.0 8240.0 0.17 309768.0 43200.0 0.9 0.7542 0.8244 2060044 SPBio_000619 CC(=O)Oc1cc(cc(OC(=O)C)c1OC(=O)C)c2coc3cc(OC(=O)C)c(OC(=O)C)c(OC(=O)C)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O22 compound treatment 282376.0 20500.0 0.41 325016.0 58400.0 1.22 1.1538 0.8973 2060156 SPBio_000620 CCC(C)C(O)C(=O)O[C@H]1[C@H](OC=O)C(C(=C)C2(O)C(=O)C[C@@H](c3ccoc3)[C@]12C)[C@]4(C)C(CC(=O)OC)[C@@](C)(COC(=O)C)OC(=O)C[C@@H]4OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O23 mock treatment 271705.0 9780.0 0.2 308205.0 41600.0 0.87 0.7532 0.8469 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 O24 mock treatment 282077.0 20200.0 0.41 269134.0 2540.0 0.05 0.3263 0.7922 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P01 mock treatment 300459.0 38500.0 0.78 304901.0 38300.0 0.8 1.1167 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P02 mock treatment 262419.0 493.0 0.01 310501.0 43900.0 0.91 0.6539 0.7148 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P03 compound treatment 342897.0 81000.0 1.64 344404.0 77800.0 1.62 2.307 1.0 1001332 SPBio_000621 CN(C)CCC[C@]1(OCc2cc(C#N)ccc21)c3ccc(F)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P04 compound treatment 278897.0 17000.0 0.34 315756.0 49200.0 1.02 0.9675 0.8955 2060433 SPBio_000622 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O[C@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P05 compound treatment 2950.0 -259000.0 -5.25 2755.0 -264000.0 -5.5 -7.599 -0.9997 1228 SPBio_000623 CC[Hg]Sc1ccccc1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P06 compound treatment 287358.0 25400.0 0.52 308223.0 41600.0 0.87 0.9779 0.9691 336 SPBio_000624 COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(=O)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P07 compound treatment 251294.0 -10600.0 -0.22 256530.0 -10100.0 -0.21 -0.3006 -0.9999 1210108 SPBio_000625 Oc1ccc2cccc(O)c(=O)c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P08 compound treatment 4017.0 -258000.0 -5.23 5355.0 -261000.0 -5.44 -7.5454 -0.9998 1043 SPBio_000626 O[Hg]c1c(O)c(Br)cc2c(c3ccccc3C(=O)O)c4cc(Br)c(=O)cc4oc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P09 compound treatment 275357.0 13400.0 0.27 302741.0 36200.0 0.75 0.7251 0.9054 932 SPBio_000627 NCCCCC(N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P10 compound treatment 274254.0 12300.0 0.25 290215.0 23600.0 0.49 0.5247 0.9506 2060324 SPBio_000628 CC12CC[C@@H]3[C@H](CC3(C)C)C(=C)CC2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P11 compound treatment 294875.0 32900.0 0.67 296538.0 29900.0 0.62 0.9135 0.9994 1032444 SPBio_000629 CC(=O)Oc1c(C)cccc1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P12 compound treatment 242000.0 -19900.0 -0.4 191458.0 -75100.0 -1.57 -1.3924 -0.8614 2060355 SPBio_000630 CC1=C(C=C)/C(=C/c2[nH]c(Cc3[nH]c(\C=C\4/NC(=O)C(=C4C)C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)/NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P13 compound treatment 278509.0 16600.0 0.34 255052.0 -11500.0 -0.24 0.0677 0.1639 1578 SPBio_000631 CC1=NCCc2c1[nH]c3cc(O)ccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P14 compound treatment 270043.0 8120.0 0.16 270927.0 4340.0 0.09 0.1802 0.9601 3174615 SPBio_000632 CC(C)CCCC(C)[C@H]1CCC2C3CC=C4CC(=O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P15 compound treatment 260283.0 -1640.0 -0.03 269355.0 2760.0 0.06 0.0172 0.2581 3173998 SPBio_000633 CC(=O)O[C@@H]1C2CC[C@@H]3C1(C[C@@]2(C)O)C[C@@H](O)[C@@]4(O)[C@@H](C[C@H](O)C4(C)C)[C@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P16 compound treatment 271710.0 9780.0 0.2 257818.0 -8770.0 -0.18 0.011 0.0409 3173217 SPBio_000634 CCN1C[C@@]2(COC)C3[C@@H](OC)[C@H]4[C@@H]1[C@@]3(C5C[C@@]6(O)[C@H](OC(=O)c7ccccc7)C5[C@]4(OC(=O)C)[C@@H](O)[C@@H]6OC)C(C[C@H]2O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P17 compound treatment 235392.0 -26500.0 -0.54 275920.0 9330.0 0.19 -0.2429 -0.4248 2069287 SPBio_000635 CCCCCC1C(CC(=O)OC)CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P18 compound treatment 243706.0 -18200.0 -0.37 258744.0 -7850.0 -0.16 -0.3768 -0.9328 425 SPBio_000636 Oc1ccc(cc1)c2coc3cc(O)cc(O)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P19 compound treatment 276288.0 14400.0 0.29 269251.0 2660.0 0.06 0.2451 0.8268 1229 SPBio_000637 CC(=O)N[C@H]1[C@@H](O)C[C@](O)(O[C@@H]1C(O)[C@H](O)CO)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P20 compound treatment 259139.0 -2790.0 -0.06 251355.0 -15200.0 -0.32 -0.2644 -0.8201 2060371 SPBio_000638 COC(=O)C[C@H]1C(C)(C)C2(O)OC34CC2C(=O)[C@]1(C)C4CC[C@@]5(C)[C@@H](OC(=O)C=C35)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P21 compound treatment 244053.0 -17900.0 -0.36 264779.0 -1810.0 -0.04 -0.2829 -0.7766 2070 SPBio_000639 COc1ccc(cc1)c2coc3cc(O)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P22 compound treatment 251992.0 -9930.0 -0.2 292174.0 25600.0 0.53 0.2345 0.4115 1000253 SPBio_000640 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P23 mock treatment 251188.0 -10700.0 -0.22 252043.0 -14500.0 -0.3 -0.3682 -0.9868 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2159 P24 mock treatment 249791.0 -12100.0 -0.25 255282.0 -11300.0 -0.24 -0.3405 -0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A01 mock treatment 196008.0 -73600.0 -1.49 233010.0 -32300.0 -0.67 -1.5313 -0.9354 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A02 mock treatment 234226.0 -35400.0 -0.72 251034.0 -14300.0 -0.3 -0.7179 -0.9242 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A03 compound treatment 255514.0 -14100.0 -0.29 282468.0 17100.0 0.36 0.0503 0.11 2060176 SPBio_000641 CC(=O)/C=C\[C@H]1[C@](C)(O)CCC2C(C)(C)CCC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A04 compound treatment 258621.0 -11000.0 -0.22 236057.0 -29300.0 -0.61 -0.5888 -0.9068 3057756 SPBio_000642 C1CCN2C[C@H]3C[C@@H](CN4CCCC[C@H]34)[C@@H]2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A05 compound treatment 250095.0 -19500.0 -0.4 251996.0 -13300.0 -0.28 -0.4763 -0.985 1016582 SPBio_000643 COc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A06 compound treatment 236158.0 -33500.0 -0.68 258930.0 -6400.0 -0.13 -0.5739 -0.8303 1151 SPBio_000644 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A07 compound treatment 236012.0 -33600.0 -0.68 250447.0 -14900.0 -0.31 -0.701 -0.9365 3054108 SPBio_000645 Nc1nc2ncc(=O)[nH]c2c(=O)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A08 compound treatment 231958.0 -37700.0 -0.76 240431.0 -24900.0 -0.52 -0.9066 -0.9823 1023016 SPBio_000646 COc1ccc2ccc(=O)oc2c1CC=C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A09 compound treatment 256590.0 -13000.0 -0.26 262128.0 -3210.0 -0.07 -0.2339 -0.8589 2060374 SPBio_000647 CCC(C)C(OC(=O)C)C(=O)O[C@H]1[C@H](O)C2[C@@]3(C)C=CC(=O)C(C)(C)C3C[C@@H](OC(=O)C(O)C(C)C)[C@@]2(C)[C@]45O[C@@H]5C[C@@H](c6ccoc6)[C@]14C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A10 compound treatment 7962.0 -262000.0 -5.3 3610.0 -262000.0 -5.45 -7.6063 -0.9999 2549 SPBio_000648 C[n+]1cc2c3OCOc3ccc2c4ccc5cc6OCOc6cc5c14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A11 compound treatment 206658.0 -63000.0 -1.28 244573.0 -20800.0 -0.43 -1.2083 -0.8966 2069225 SPBio_000649 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c5c(=O)c(O)cc(cc45)[C@H]6Oc7cc(O)cc(O)c7C[C@H]6OC(=O)c8cc(O)c(O)c(O)c8 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A12 compound treatment 241678.0 -27900.0 -0.57 260295.0 -5040.0 -0.1 -0.4747 -0.8241 3059440 SPBio_000650 OC(=O)C1CC(CN2CCCCC12)[C@@H]3CCCCN3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A13 compound treatment 242888.0 -26700.0 -0.54 243456.0 -21900.0 -0.46 -0.7054 -0.9963 2546 SPBio_000651 COC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A14 compound treatment 232437.0 -37200.0 -0.75 226733.0 -38600.0 -0.8 -1.1015 -0.9995 2060439 SPBio_000652 COC1=C(OC)C(=O)C(=C(C)C1=O)C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC\C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A15 compound treatment 281993.0 12400.0 0.25 282903.0 17600.0 0.37 0.4363 0.9831 3078460 SPBio_000653 CO/N=C(\C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)/C=C\c3scnc3C)/c4csc(N)n4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A16 compound treatment 277927.0 8310.0 0.17 239459.0 -25900.0 -0.54 -0.262 -0.4638 1307902 SPBio_000654 CN1CCCCC1c2ccc(nc2)c3cccnc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A17 compound treatment 244720.0 -24900.0 -0.5 250881.0 -14500.0 -0.3 -0.5697 -0.9695 2575 SPBio_000655 CCS(=O)(=O)CCn1c(C)ncc1[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A18 compound treatment 260790.0 -8820.0 -0.18 271148.0 5810.0 0.12 -0.0408 -0.1889 3078270 SPBio_000656 CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A19 compound treatment 242943.0 -26700.0 -0.54 228462.0 -36900.0 -0.77 -0.9255 -0.9852 3480341 SPBio_000657 CN1CCCC(CC1)n2nc(Cc3ccc(Cl)cc3)c4ccccc4c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A20 compound treatment 233046.0 -36600.0 -0.74 258968.0 -6370.0 -0.13 -0.618 -0.8206 1204574 SPBio_000658 COc1c(oc2cc3oc(=O)ccc3cc12)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A21 compound treatment 3682.0 -266000.0 -5.39 2855.0 -262000.0 -5.47 -7.6787 -1.0 1351 SPBio_000659 Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]3c(C)cc(N)c4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A22 compound treatment 185643.0 -84000.0 -1.7 177632.0 -87700.0 -1.83 -2.4957 -0.9994 1008178 SPBio_000660 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2C)c(OC)c1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A23 mock treatment 237711.0 -31900.0 -0.65 220357.0 -45000.0 -0.94 -1.1199 -0.9836 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 A24 mock treatment 243013.0 -26600.0 -0.54 273777.0 8440.0 0.18 -0.2569 -0.453 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B01 mock treatment 245506.0 -24100.0 -0.49 253496.0 -11800.0 -0.25 -0.5199 -0.9498 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B02 mock treatment 302779.0 33200.0 0.67 278603.0 13300.0 0.28 0.6709 0.9229 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B03 compound treatment 298708.0 29100.0 0.59 282250.0 16900.0 0.35 0.6663 0.9697 2069255 SPBio_000661 Oc1cc(cc(O)c1O)c2coc3cc(O)c(O)c(O)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B04 compound treatment 293692.0 24100.0 0.49 290072.0 24700.0 0.52 0.7096 0.9996 2060101 SPBio_000662 COc1ccc(cc1OC)[C@H]2Oc3c(I)c(OC)cc(OC)c3C[C@@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B05 compound treatment 3275.0 -266000.0 -5.4 4145.0 -261000.0 -5.44 -7.6656 -1.0 901 SPBio_000663 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B06 compound treatment 283152.0 13500.0 0.27 273064.0 7730.0 0.16 0.308 0.9677 910 SPBio_000664 CN1CC(CNC(=O)OCc2ccccc2)C[C@@H]3C1Cc4cn(C)c5cccc3c45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B07 compound treatment 285149.0 15500.0 0.31 319545.0 54200.0 1.13 1.0213 0.8711 1315 SPBio_000665 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B08 compound treatment 300328.0 30700.0 0.62 282577.0 17200.0 0.36 0.6943 0.9658 683 SPBio_000666 Cc1ncc([N+](=O)[O-])n1CCO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B09 compound treatment 196880.0 -72700.0 -1.47 195448.0 -69900.0 -1.46 -2.0721 -1.0 2069270 SPBio_000667 CC(C)CCCC(C)C1CCC2C3CC(=O)[C@H]4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B10 compound treatment 270918.0 1310.0 0.03 157194.0 -108000.0 -2.25 -1.5743 -0.6988 3059437 SPBio_000668 OC[C@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B11 compound treatment 286523.0 16900.0 0.34 275028.0 9690.0 0.2 0.3852 0.9682 1044412 SPBio_000669 Oc1cc2ccccc2oc1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B12 compound treatment 3172.0 -266000.0 -5.4 2475.0 -263000.0 -5.48 -7.6916 -1.0 1090 SPBio_000670 CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B13 compound treatment 278610.0 9000.0 0.18 266552.0 1220.0 0.03 0.1469 0.7978 3198326 SPBio_000671 O[C@@H]1O[C@H](COC(=O)CC[N+](=O)[O-])[C@@H](OC(=O)CC[N+](=O)[O-])[C@H](OC(=O)CC[N+](=O)[O-])[C@H]1OC(=O)CC[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B14 compound treatment 274711.0 5100.0 0.1 58496.0 -207000.0 -4.31 -2.9739 -0.6899 1259 SPBio_000672 CCc1nc(N)nc(N)c1c2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B15 compound treatment 167762.0 -102000.0 -2.06 257259.0 -8070.0 -0.17 -1.579 -0.7622 3177521 SPBio_000673 COc1cc(cc(OC)c1OC)[C@H]2[C@H]3[C@H](COC3=O)[C@@H](OC(=O)C)c4cc5OCOc5cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B16 compound treatment 245269.0 -24300.0 -0.49 145021.0 -120000.0 -2.51 -2.1213 -0.8304 2551 SPBio_000674 COc1cc(NC(C)CCCN)c2ncccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B17 compound treatment 302486.0 32900.0 0.67 253556.0 -11800.0 -0.25 0.2978 0.4193 1050602 SPBio_000675 COc1ccc(CC(=O)c2ccc(O)cc2O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B18 compound treatment 245120.0 -24500.0 -0.5 249093.0 -16200.0 -0.34 -0.5903 -0.9825 763 SPBio_000676 CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B19 compound treatment 313527.0 43900.0 0.89 293871.0 28500.0 0.59 1.0499 0.9807 2069259 SPBio_000677 C[C@@]12CCC3C(CC[C@H]4C[C@H](O)CC[C@@]43C)C2CC[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B20 compound treatment 14230.0 -255000.0 -5.18 21502.0 -244000.0 -5.08 -7.2528 -1.0 368 SPBio_000678 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B21 compound treatment 303349.0 33700.0 0.68 238378.0 -27000.0 -0.56 0.0865 0.0978 3172708 SPBio_000679 CCC(C)C(=O)O[C@H]1[C@H](O)C2C(CN3CC(C)CCC3[C@@]2(C)O)C4C[C@]5(O[C@@]6(O)C7C(OC(=O)C)[C@@H](OC(=O)C)C5[C@@]41O)[C@@]7(C)CCC6OC(=O)C(C)(O)C(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B22 compound treatment 300135.0 30500.0 0.62 254346.0 -11000.0 -0.23 0.2757 0.4179 3198420 SPBio_000680 CC[C@]1(O)CC2CN(C1)CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@H]7[C@@]86CCN9CC=C[C@](CC)([C@H]98)[C@@H](OC(=O)C)[C@]7(O)C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B23 mock treatment 318117.0 48500.0 0.98 279074.0 13700.0 0.29 0.8977 0.8766 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 B24 mock treatment 283298.0 13700.0 0.28 275360.0 10000.0 0.21 0.3439 0.9902 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C01 mock treatment 214794.0 -54800.0 -1.11 251205.0 -14100.0 -0.29 -0.994 -0.8646 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C02 mock treatment 265896.0 -3720.0 -0.08 255513.0 -9820.0 -0.2 -0.1979 -0.9079 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C03 compound treatment 41941.0 -228000.0 -4.62 44229.0 -221000.0 -4.61 -6.5208 -1.0 2060254 SPBio_000681 CC(=O)CC1CCCCN1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C04 compound treatment 46907.0 -223000.0 -4.51 67665.0 -198000.0 -4.12 -6.1044 -0.9989 2060501 SPBio_000682 CC(C)(OC(=O)c1ccccc1)[C@@H]2Cc3cc4ccc(=O)oc4cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C05 compound treatment 210309.0 -59300.0 -1.2 209443.0 -55900.0 -1.16 -1.6734 -0.9999 2060245 SPBio_000683 OC[C@H]1O[C@@](CO)(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C06 compound treatment 142762.0 -127000.0 -2.57 155744.0 -110000.0 -2.28 -3.4328 -0.9982 3177461 SPBio_000684 CN1C2C[C@H](O)[C@@H]1C[C@H](C2)OC(=O)[C@H](CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C07 compound treatment 266938.0 -2670.0 -0.05 268367.0 3030.0 0.06 0.0063 0.0763 2069293 SPBio_000685 CCc1ccc2c(O)c3C(=O)c4c(O)ccc(O)c4C(=O)c3cc2c1C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C08 compound treatment 260959.0 -8650.0 -0.18 281587.0 16300.0 0.34 0.1154 0.3026 1296906 SPBio_000686 COc1ccc(C(=O)CC(=O)O)c2OC(C)(C)C=Cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C09 compound treatment 194693.0 -74900.0 -1.52 43418.0 -222000.0 -4.62 -4.343 -0.8925 1092958 SPBio_000687 COC1=CC(=O)C(=CC1=O)C(C=C)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C10 compound treatment 315009.0 45400.0 0.92 309597.0 44300.0 0.92 1.3028 1.0 1253 SPBio_000688 C[C@H]1OC=C2C(=C(C(=O)O)C(=O)C(=C2[C@@H]1C)C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C11 compound treatment 254896.0 -14700.0 -0.3 283851.0 18500.0 0.39 0.0618 0.1268 1262 SPBio_000689 NC[C@H]1CC[C@@H](CC1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C12 compound treatment 293195.0 23600.0 0.48 273266.0 7930.0 0.17 0.4549 0.8993 1216977 SPBio_000690 CC1(C)Oc2ccc3ccc(=O)oc3c2CC1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C13 compound treatment 279356.0 9740.0 0.2 266682.0 1350.0 0.03 0.1595 0.7996 1000143 SPBio_000691 NC(Cn1ccc(=O)c(O)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C14 compound treatment 260732.0 -8880.0 -0.18 242977.0 -22400.0 -0.47 -0.4566 -0.9145 2321 SPBio_000692 COc1ccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C15 compound treatment 303245.0 33600.0 0.68 271660.0 6330.0 0.13 0.5753 0.8285 3172716 SPBio_000693 NC(=O)N/N=C/c1ccc(o1)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C16 compound treatment 261769.0 -7840.0 -0.16 247995.0 -17300.0 -0.36 -0.3679 -0.9321 3055383 SPBio_000694 CC(C)(O)[C@@H]1Cc2cc3ccc(=O)oc3cc2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C17 compound treatment 225142.0 -44500.0 -0.9 256476.0 -8860.0 -0.18 -0.768 -0.8345 3078461 SPBio_000695 NCCc1ccccc1S(=O)(=O)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C18 compound treatment 287541.0 17900.0 0.36 271833.0 6500.0 0.14 0.3528 0.9095 1501 SPBio_000696 NCCc1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C19 compound treatment 154832.0 -115000.0 -2.33 98433.0 -167000.0 -3.48 -4.104 -0.9809 3198318 SPBio_000697 C[C@H]1CCCC(=O)CCC/C=C/c2cc(O)cc(O)c2C(=O)O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C20 compound treatment 296350.0 26700.0 0.54 293982.0 28600.0 0.6 0.8053 0.9988 1368 SPBio_000698 CCC(C)C(N)C1=NC(CS1)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NCCCCC2NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4ccccc4)NC(=O)C(NC(=O)C(CCCN)NC2=O)C(C)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C21 compound treatment 281217.0 11600.0 0.24 206778.0 -58600.0 -1.22 -0.6962 -0.5604 2141061 SPBio_000699 Cc1cc2nc3c(=O)[nH]c(=O)nc3n(C[C@@H](O)[C@@H](O)[C@@H](O)CO)c2cc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C22 compound treatment 282125.0 12500.0 0.25 265213.0 -121.0 0.0 0.1776 0.7001 2060491 SPBio_000700 CC(C)CC(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C23 mock treatment 293056.0 23400.0 0.48 239530.0 -25800.0 -0.54 -0.044 -0.0614 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 C24 mock treatment 252951.0 -16700.0 -0.34 211302.0 -54000.0 -1.13 -1.0348 -0.8805 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D01 mock treatment 269680.0 67.7 0.0 266961.0 1630.0 0.03 0.0249 0.7351 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D02 mock treatment 280140.0 10500.0 0.21 263559.0 -1770.0 -0.04 0.1248 0.576 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D03 compound treatment 312443.0 42800.0 0.87 290008.0 24700.0 0.51 0.9775 0.9687 2060503 SPBio_000701 C1Oc2ccc(cc2O1)[C@H]3OC[C@@H]4[C@@H](OC[C@H]34)c5ccc6OCOc6c5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D04 compound treatment 40775.0 -229000.0 -4.64 9441.0 -256000.0 -5.33 -7.05 -0.9976 1070 SPBio_000702 CCC(C(CC)c1ccc(O)cc1)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D05 compound treatment 322987.0 53400.0 1.08 321781.0 56400.0 1.18 1.5967 0.9991 2060397 SPBio_000703 COc1ccc2C(=O)/C(=C/c3ccc(OC)c(O)c3)/COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D06 compound treatment 304800.0 35200.0 0.71 340300.0 75000.0 1.56 1.6088 0.937 804 SPBio_000704 COc1c(C)c2COC(=O)c2c(O)c1C/C=C(\C)/CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D07 compound treatment 285928.0 16300.0 0.33 302946.0 37600.0 0.78 0.788 0.9264 2069258 SPBio_000705 COc1ccc(c(OC)c1O)c2coc3cc(O)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D08 compound treatment 306543.0 36900.0 0.75 274052.0 8720.0 0.18 0.6578 0.8539 1091345 SPBio_000706 Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O)cnc2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D09 compound treatment 258994.0 -10600.0 -0.22 293969.0 28600.0 0.6 0.2696 0.4251 1022 SPBio_000707 COc1cc(OC)c2ccc(=O)oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D10 compound treatment 271518.0 1910.0 0.04 290761.0 25400.0 0.53 0.4019 0.7567 909 SPBio_000708 COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D11 compound treatment 308570.0 39000.0 0.79 275135.0 9800.0 0.2 0.7028 0.8616 2060379 SPBio_000709 COc1ccc(cc1)c2coc3c(OC)c(OC)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D12 compound treatment 101692.0 -168000.0 -3.4 65444.0 -200000.0 -4.16 -5.3518 -0.995 599 SPBio_000710 Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D13 compound treatment 258386.0 -11200.0 -0.23 217739.0 -47600.0 -0.99 -0.8621 -0.8474 3173357 SPBio_000711 CC(=C)[C@@H]1CC[C@@]2(CCC3[C@H](CCC4[C@@]3(C)CCC5C(C)(C)[C@H](O)CC[C@@]54C)C12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D14 compound treatment 278990.0 9380.0 0.19 202877.0 -62500.0 -1.3 -0.7856 -0.5974 3173213 SPBio_000712 COc1ccc(C[C@H](N)C(=O)N[C@H]2[C@@H](O)C(O[C@@H]2CO)n3cnc4c(ncnc34)N(C)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D15 compound treatment 307917.0 38300.0 0.78 254538.0 -10800.0 -0.22 0.3901 0.4825 2069325 SPBio_000713 OC(=O)/C=C/C=C/c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D16 compound treatment 6220.0 -263000.0 -5.34 4676.0 -261000.0 -5.43 -7.6155 -1.0 3078281 SPBio_000714 C[C@H]1OC(C(O)[C@@H]1O)n2cc(F)c(=O)[nH]c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D17 compound treatment 274924.0 5310.0 0.11 275442.0 10100.0 0.21 0.2251 0.9515 3173762 SPBio_000715 CC1OC(O[C@@H]/2CC3O[C@@](O)(C[C@H](O)C3C(=O)O)CC(O)CC(O)C(O)CCC(O)CC(O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C2)C(O)[C@H](N)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D18 compound treatment 268753.0 -859.0 -0.02 261601.0 -3730.0 -0.08 -0.0673 -0.8446 1477 SPBio_000716 O=C1O[Pt]OC(=O)C21CCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D19 compound treatment 234958.0 -34700.0 -0.7 212208.0 -53100.0 -1.11 -1.2794 -0.9759 1907763 SPBio_000717 Oc1ccc(/C=C/C(=O)OCCc2ccccc2)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D20 compound treatment 242289.0 -27300.0 -0.55 205648.0 -59700.0 -1.24 -1.2709 -0.9337 1475 SPBio_000718 Cl[Pt]Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D21 compound treatment 298462.0 28800.0 0.58 269656.0 4320.0 0.09 0.4772 0.8065 1913676 SPBio_000719 COc1ccc(cc1)C(=O)/C=C/c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D22 compound treatment 307372.0 37800.0 0.77 255159.0 -10200.0 -0.21 0.3914 0.4928 2080598 SPBio_000720 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@H](O)CC2CC(=O)NC(=O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D23 mock treatment 272555.0 2940.0 0.06 258217.0 -7120.0 -0.15 -0.0627 -0.392 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 D24 mock treatment 227780.0 -41800.0 -0.85 207939.0 -57400.0 -1.2 -1.4452 -0.9858 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E01 mock treatment 245741.0 -23900.0 -0.48 266881.0 1550.0 0.03 -0.3194 -0.6585 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E02 mock treatment 250360.0 -19300.0 -0.39 275770.0 10400.0 0.22 -0.1222 -0.2736 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E03 compound treatment 254056.0 -15600.0 -0.32 240447.0 -24900.0 -0.52 -0.5896 -0.9716 2060173 SPBio_000721 CC(C)C1CCC(C)(O)C2CCC(=CC12)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E04 compound treatment 243315.0 -26300.0 -0.53 296496.0 31200.0 0.65 0.0821 0.0977 2060454 SPBio_000722 Oc1cc(O)c2c(=O)cc(oc2c1)c3cc(O)c(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E05 compound treatment 280572.0 11000.0 0.22 279149.0 13800.0 0.29 0.3606 0.9918 3174242 SPBio_000723 OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E06 compound treatment 260365.0 -9250.0 -0.19 273591.0 8260.0 0.17 -0.0109 -0.0429 1482 SPBio_000724 CN1CCc2cc3OCOc3cc2C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E07 compound treatment 289836.0 20200.0 0.41 298083.0 32700.0 0.68 0.7723 0.9703 1000946 SPBio_000725 COc1ccc(CC2N(C)CCc3cc(OC)c(OC)cc23)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E08 compound treatment 279050.0 9440.0 0.19 270040.0 4710.0 0.1 0.2046 0.9518 1398 SPBio_000726 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OC(=O)C)c(C)c(C)c2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E09 compound treatment 273293.0 3680.0 0.07 289089.0 23800.0 0.49 0.4027 0.8046 3078462 SPBio_000727 [Na+].[O-]C(=O)CF 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E10 compound treatment 256814.0 -12800.0 -0.26 47463.0 -218000.0 -4.54 -3.3929 -0.7463 1588 SPBio_000728 CC(=O)C1C(=O)C=C2Oc3c(c(O)c(C)c(O)c3C(=O)C)C2(C)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E11 compound treatment 285812.0 16200.0 0.33 294185.0 28900.0 0.6 0.6572 0.9596 465 SPBio_000729 NCCc1c[nH]cn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E12 compound treatment 293359.0 23700.0 0.48 259189.0 -6140.0 -0.13 0.2499 0.5017 2060490 SPBio_000730 C/C=C(\C)/C(=O)O[C@H]1[C@@H](OC(=O)C)C(C)(C)Oc2ccc3ccc(=O)oc3c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E13 compound treatment 280313.0 10700.0 0.22 256471.0 -8860.0 -0.18 0.0228 0.0802 1000060 SPBio_000731 COC(=O)C1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E14 compound treatment 270491.0 879.0 0.02 299233.0 33900.0 0.71 0.512 0.7247 1000136 SPBio_000732 CC12CCC3C(=CCc4cc(O)ccc34)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E15 compound treatment 3077.0 -267000.0 -5.4 2596.0 -263000.0 -5.47 -7.6912 -1.0 1243 SPBio_000733 OC[C@H]1OC(C[C@H]1O)n2cc(F)c(=O)[nH]c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E16 compound treatment 111324.0 -158000.0 -3.21 113761.0 -152000.0 -3.16 -4.5019 -1.0 2060357 SPBio_000734 CC(=O)O[C@@H]1CC2C(C)(C)CCC(=O)[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E17 compound treatment 217747.0 -51900.0 -1.05 192019.0 -73300.0 -1.53 -1.8235 -0.9834 1498 SPBio_000735 OC(=O)P(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E18 compound treatment 286150.0 16500.0 0.34 269817.0 4480.0 0.09 0.3031 0.8709 3078271 SPBio_000736 COC(=O)C[C@H]1C(C)(C)[C@H](O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CC[C@H](C3=C)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E19 compound treatment 295202.0 25600.0 0.52 299974.0 34600.0 0.72 0.8771 0.9869 3198319 SPBio_000737 O=C1O[C@]2(C[C@H]3C=CC2=C1)[C@H]4CCCCN34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E20 compound treatment 270238.0 626.0 0.01 278247.0 12900.0 0.27 0.1992 0.7396 2060049 SPBio_000738 Cc1cc(=O)c2c(O)c(C)c(O)cc2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E21 compound treatment 305209.0 35600.0 0.72 277531.0 12200.0 0.25 0.69 0.9018 1290 SPBio_000739 OC(=O)c1ccc(cc1)S(=O)(=O)N(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E22 compound treatment 315222.0 45600.0 0.92 267116.0 1780.0 0.04 0.6801 0.7349 2060435 SPBio_000740 COC(=O)C(OC(=O)C)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E23 mock treatment 311835.0 42200.0 0.86 263560.0 -1770.0 -0.04 0.5791 0.676 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 E24 mock treatment 251378.0 -18200.0 -0.37 232292.0 -33000.0 -0.69 -0.7481 -0.9575 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F01 mock treatment 260206.0 -9410.0 -0.19 249833.0 -15500.0 -0.32 -0.3632 -0.9684 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F02 mock treatment 311351.0 41700.0 0.85 298894.0 33600.0 0.7 1.0927 0.9955 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F03 compound treatment 315852.0 46200.0 0.94 309389.0 44100.0 0.92 1.3118 0.9999 2060314 SPBio_000741 COC(=O)c1c(C)c2Oc3c(Cl)c(OC)c(Cl)c(C)c3C(=O)Oc2c(C)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F04 compound treatment 322721.0 53100.0 1.08 361310.0 96000.0 2.0 2.1752 0.9578 1000048 SPBio_000742 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F05 compound treatment 307344.0 37700.0 0.76 268315.0 2980.0 0.06 0.5848 0.762 401 SPBio_000743 COc1cccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F06 compound treatment 297944.0 28300.0 0.57 237952.0 -27400.0 -0.57 0.0028 0.0034 1537 SPBio_000744 NC(Cc1ccc(F)cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F07 compound treatment 174941.0 -94700.0 -1.92 112506.0 -153000.0 -3.18 -3.6084 -0.9706 2060376 SPBio_000745 CC(=O)Oc1cccc2C(=O)c3cc(cc(OC(=O)C)c3C(=O)c12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F08 compound treatment 312476.0 42900.0 0.87 319323.0 54000.0 1.12 1.4098 0.9919 383 SPBio_000746 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F09 compound treatment 292453.0 22800.0 0.46 323264.0 57900.0 1.21 1.1808 0.9135 1334 SPBio_000747 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F10 compound treatment 264694.0 -4920.0 -0.1 268895.0 3560.0 0.07 -0.018 -0.1452 767 SPBio_000748 OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC(C#N)c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F11 compound treatment 306930.0 37300.0 0.76 306777.0 41400.0 0.86 1.1455 0.9978 1314 SPBio_000749 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3ccccc3C[C@H]2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F12 compound treatment 208682.0 -60900.0 -1.24 148961.0 -116000.0 -2.42 -2.5877 -0.9511 598 SPBio_000750 Oc1cc2c(=O)oc3c(O)c(O)cc4c(=O)oc(c1O)c2c43 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F13 compound treatment 251454.0 -18200.0 -0.37 227522.0 -37800.0 -0.79 -0.8173 -0.94 2060316 SPBio_000751 COc1c2C=CC(C)(C)Oc2cc3occ(c4ccc5OCOc5c4)c(=O)c13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F14 compound treatment 314752.0 45100.0 0.92 278165.0 12800.0 0.27 0.8361 0.877 1539 SPBio_000752 C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F15 compound treatment 159958.0 -110000.0 -2.22 186568.0 -78800.0 -1.64 -2.7322 -0.9888 960 SPBio_000753 C1N2CN3CN1CN(C2)C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F16 compound treatment 226957.0 -42700.0 -0.86 223050.0 -42300.0 -0.88 -1.2344 -1.0 1371 SPBio_000754 CN(C)c1nc(nc(n1)N(C)C)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F17 compound treatment 210175.0 -59400.0 -1.2 195048.0 -70300.0 -1.46 -1.8874 -0.9953 437 SPBio_000755 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F18 compound treatment 172043.0 -97600.0 -1.98 41938.0 -223000.0 -4.65 -4.6895 -0.9274 1135 SPBio_000756 OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F19 compound treatment 16897.0 -253000.0 -5.12 313073.0 47700.0 0.99 -2.9194 -0.5594 1005 SPBio_000757 OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F20 compound treatment 291587.0 22000.0 0.45 259995.0 -5340.0 -0.11 0.2364 0.5148 726 SPBio_000758 CCOC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F21 compound treatment 265385.0 -4230.0 -0.09 264595.0 -739.0 -0.02 -0.0715 -0.8209 3078274 SPBio_000759 N[C@H](CO)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F22 compound treatment 285732.0 16100.0 0.33 270751.0 5420.0 0.11 0.3109 0.8992 946 SPBio_000760 OCCNC(=O)Cn1ccnc1[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F23 mock treatment 302790.0 33200.0 0.67 272200.0 6870.0 0.14 0.5768 0.8387 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 F24 mock treatment 264581.0 -5030.0 -0.1 261521.0 -3810.0 -0.08 -0.1283 -0.9923 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G01 mock treatment 252300.0 -17300.0 -0.35 256862.0 -8470.0 -0.18 -0.373 -0.9494 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G02 mock treatment 258324.0 -11300.0 -0.23 280084.0 14800.0 0.31 0.0555 0.1448 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G03 compound treatment 290657.0 21000.0 0.43 281400.0 16100.0 0.33 0.5384 0.9928 1107153 SPBio_000761 CC(=O)c1cc2C=CC(C)(C)Oc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G04 compound treatment 264500.0 -5110.0 -0.1 281320.0 16000.0 0.33 0.1622 0.4651 2069251 SPBio_000762 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C[C@H](O)[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G05 compound treatment 274727.0 5110.0 0.1 306684.0 41400.0 0.86 0.6825 0.7865 1984013 SPBio_000763 C/C=C/c1ccc2OCOc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G06 compound treatment 289375.0 19800.0 0.4 263574.0 -1760.0 -0.04 0.2574 0.6397 3078272 SPBio_000764 [Na+].[O-]S(=O)(=O)CCS 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G07 compound treatment 272155.0 2540.0 0.05 262978.0 -2360.0 -0.05 0.0017 0.0246 2561 SPBio_000765 Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G08 compound treatment 278478.0 8870.0 0.18 308135.0 42800.0 0.89 0.7576 0.8329 1225 SPBio_000766 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G09 compound treatment 268232.0 -1380.0 -0.03 248504.0 -16800.0 -0.35 -0.2677 -0.7611 2069276 SPBio_000767 COc1cc(cc(OCc2ccccc2)c1OC)c3coc4cc(OCc5ccccc5)c(OC)c(O)c4c3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G10 compound treatment 265641.0 -3970.0 -0.08 284681.0 19300.0 0.4 0.2281 0.5549 2060402 SPBio_000768 COc1ccc2CC[C@H]3CC(=O)CC[C@]3(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G11 compound treatment 273697.0 4080.0 0.08 279529.0 14200.0 0.3 0.2677 0.8716 1001923 SPBio_000769 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G12 compound treatment 279921.0 10300.0 0.21 308715.0 43400.0 0.9 0.7868 0.8482 2069256 SPBio_000770 COc1cc2OCOc2cc1/C=C/C(=O)c3cc(OC)c(OC)cc3OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G13 compound treatment 211888.0 -57700.0 -1.17 192811.0 -72500.0 -1.51 -1.8958 -0.992 1189 SPBio_000771 CO[C@]1(NC(=O)Cc2cccs2)[C@H]3SCC(=C(N3C1=O)C(=O)O)COC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G14 compound treatment 282728.0 13100.0 0.27 274106.0 8770.0 0.18 0.3172 0.9833 703 SPBio_000772 OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G15 compound treatment 282817.0 13200.0 0.27 271505.0 6170.0 0.13 0.2802 0.9435 866 SPBio_000773 Cc1c(cc(cc1[N+](=O)[O-])[N+](=O)[O-])C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G16 compound treatment 288893.0 19300.0 0.39 273567.0 8230.0 0.17 0.3977 0.9316 976 SPBio_000774 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G17 compound treatment 275187.0 5570.0 0.11 279619.0 14300.0 0.3 0.2904 0.9121 1105 SPBio_000775 CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G18 compound treatment 287830.0 18200.0 0.37 277888.0 12600.0 0.26 0.4461 0.9857 2060370 SPBio_000776 COc1cc2OCOc2cc1c3coc4c5C=CC(C)(C)Oc5c(OC)cc4c3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G19 compound treatment 249107.0 -20500.0 -0.42 300596.0 35300.0 0.73 0.2255 0.2672 2097 SPBio_000777 CCCCCCCCCCCCCCCCOP(=O)(O)OCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G20 compound treatment 2151.0 -267000.0 -5.42 2340.0 -263000.0 -5.48 -7.7083 -1.0 935 SPBio_000778 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G21 compound treatment 265967.0 -3650.0 -0.07 247281.0 -18100.0 -0.38 -0.3182 -0.8302 3174101 SPBio_000779 CN1CCc2c(C1)c3ccccc3n2Cc4ccccc4.OS(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G22 compound treatment 293984.0 24400.0 0.49 300563.0 35200.0 0.73 0.8683 0.9815 2060092 SPBio_000780 CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CCC3C4CC=C(C(=O)C)[C@@]4(C)C(=O)CC32)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G23 mock treatment 291796.0 22200.0 0.45 278963.0 13600.0 0.28 0.5188 0.9754 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 G24 mock treatment 290823.0 21200.0 0.43 240256.0 -25100.0 -0.52 -0.0654 -0.0966 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H01 mock treatment 281342.0 11700.0 0.24 308788.0 43500.0 0.91 0.8083 0.8636 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H02 mock treatment 270079.0 467.0 0.01 297993.0 32700.0 0.68 0.4878 0.7169 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H03 compound treatment 318671.0 49100.0 0.99 337834.0 72500.0 1.51 1.7713 0.9794 3078275 SPBio_000781 C[C@@H](N)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H04 compound treatment 322961.0 53300.0 1.08 326831.0 61500.0 1.28 1.6707 0.9964 695 SPBio_000782 CC1CCC(CC1)NC(=O)N(CCCl)N=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H05 compound treatment 316399.0 46800.0 0.95 329548.0 64200.0 1.34 1.6166 0.9858 1000069 SPBio_000783 COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c6OCOc6cc7CCN(C)[C@@H](Cc8ccc(Oc1c2)cc8)c75)cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H06 compound treatment 315572.0 46000.0 0.93 278597.0 13300.0 0.28 0.8542 0.879 1394 SPBio_000784 BrCCC(=O)N1CCN(CC1)C(=O)CCBr 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H07 compound treatment 308578.0 39000.0 0.79 290864.0 25500.0 0.53 0.9347 0.9815 3078276 SPBio_000785 COC(=O)N/N=C/c1c[n+]([O-])c2ccccc2[n+]1[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H08 compound treatment 288685.0 19100.0 0.39 255138.0 -10200.0 -0.21 0.1232 0.2793 3198421 SPBio_000786 CCC(C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(=O)O)C12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H09 compound treatment 294769.0 25200.0 0.51 291515.0 26200.0 0.55 0.7463 0.9994 3078277 SPBio_000787 CN[C@H]1[C@@H](O)[C@H]2O[C@@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]4O[C@H](CO)[C@@H](N)[C@H](O)[C@H]4O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H10 compound treatment 328253.0 58600.0 1.19 308852.0 43500.0 0.91 1.4817 0.9911 1211 SPBio_000788 CON 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H11 compound treatment 294218.0 24600.0 0.5 305108.0 39800.0 0.83 0.9386 0.9705 1001954 SPBio_000789 C/C=C/1\[C@@H]2Cc3[nH]c(=O)ccc3[C@@]1(N)CC(=C2)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H12 compound treatment 299098.0 29500.0 0.6 298245.0 32900.0 0.69 0.9075 0.9977 2554 SPBio_000790 C[C@H]1[C@H]2CCC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23CN1C)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H13 compound treatment 324962.0 55300.0 1.12 290264.0 24900.0 0.52 1.1607 0.9387 3198419 SPBio_000791 COc1ccc2cc3c4cc(OC)c(OC)cc4cc[n+]3cc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H14 compound treatment 242002.0 -27600.0 -0.56 174082.0 -91300.0 -1.9 -1.74 -0.878 1307 SPBio_000792 ClC(Cl)C(c1ccc(Cl)cc1)c2ccccc2Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H15 compound treatment 319069.0 49500.0 1.0 311157.0 45800.0 0.95 1.384 0.9997 1017172 SPBio_000793 C=CCSCC=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H16 compound treatment 329470.0 59900.0 1.21 285051.0 19700.0 0.41 1.1485 0.8965 2557 SPBio_000794 COS(=O)(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H17 compound treatment 324464.0 54900.0 1.11 309007.0 43700.0 0.91 1.4297 0.995 1117560 SPBio_000795 CC(=C)C1CCC(=CC1)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H18 compound treatment 276789.0 7180.0 0.15 299416.0 34100.0 0.71 0.605 0.8347 3198422 SPBio_000796 CN[C@H]1C[C@@H](N)[C@H](O)[C@@H](O[C@@H]2O[C@H](CO)[C@@H]3OC4(O[C@@H]3[C@@H]2O)O[C@H](C(N)CO)[C@H](O)[C@H](O)[C@H]4O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H19 compound treatment 298577.0 29000.0 0.59 282364.0 17000.0 0.35 0.6661 0.9709 1047 SPBio_000797 CN(C)CCCN1c2ccccc2Sc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H20 compound treatment 333994.0 64400.0 1.31 308825.0 43500.0 0.91 1.5636 0.9841 417 SPBio_000798 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H21 compound treatment 251365.0 -18200.0 -0.37 284119.0 18800.0 0.39 0.0152 0.0281 681 SPBio_000799 CC(CN1c2ccccc2Sc3ccccc13)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H22 compound treatment 2687.0 -267000.0 -5.41 2262.0 -263000.0 -5.48 -7.7017 -1.0 3046992 SPBio_000800 CO[C@]12[C@@H]3NC3CN2C4=C([C@@H]1COC(=O)N)C(=O)C(=C(C)C4=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H23 mock treatment 321670.0 52100.0 1.06 273821.0 8490.0 0.18 0.8713 0.8142 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 H24 mock treatment 293397.0 23800.0 0.48 245165.0 -20200.0 -0.42 0.0439 0.0686 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I01 mock treatment 274006.0 4390.0 0.09 251787.0 -13500.0 -0.28 -0.1366 -0.4615 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I02 mock treatment 246081.0 -23500.0 -0.48 278060.0 12700.0 0.27 -0.1498 -0.2746 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I03 compound treatment 254346.0 -15300.0 -0.31 267551.0 2220.0 0.05 -0.1862 -0.595 647 SPBio_000801 Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I04 compound treatment 296447.0 26800.0 0.54 276098.0 10800.0 0.22 0.5433 0.9232 2060425 SPBio_000802 COC(=O)[C@@H]1OC(=O)[C@H]2O[C@@]23[C@@]1(C)CCC4[C@@]5(C)CCC(=O)C(C)(C)C5C[C@@H](OC(=O)C)[C@]43C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I05 compound treatment 315262.0 45600.0 0.93 323052.0 57700.0 1.2 1.5047 0.9916 3174492 SPBio_000803 CN1[C@H]2CC3CC1C(O)C2O3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I06 compound treatment 320074.0 50500.0 1.02 296639.0 31300.0 0.65 1.1845 0.9764 1028 SPBio_000804 Oc1ccc(cc1)C(=C2C=CC(=O)C=C2)c3ccc(O)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I07 compound treatment 283457.0 13800.0 0.28 283542.0 18200.0 0.38 0.4667 0.989 1029487 SPBio_000805 OCC(O)Cc1ccc2OCOc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I08 compound treatment 279905.0 10300.0 0.21 306547.0 41200.0 0.86 0.7547 0.8541 3198323 SPBio_000806 COc1cc(OC)c2c(=O)c(coc2c1)c3ccc4OCOc4c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I09 compound treatment 274677.0 5060.0 0.1 305037.0 39700.0 0.83 0.6575 0.7888 3078463 SPBio_000807 CCOC(=O)c1c(C)cc(OC)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I10 compound treatment 315543.0 45900.0 0.93 294398.0 29100.0 0.61 1.0866 0.9783 986 SPBio_000808 CN1CC(=O)NC1=N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I11 compound treatment 301349.0 31700.0 0.64 273157.0 7820.0 0.16 0.5702 0.8591 2060194 SPBio_000809 COc1cc(O)c(C(=O)O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I12 compound treatment 303625.0 34000.0 0.69 304118.0 38800.0 0.81 1.0589 0.9969 1013 SPBio_000810 Cc1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I13 compound treatment 296720.0 27100.0 0.55 272823.0 7490.0 0.16 0.4989 0.8733 1514 SPBio_000811 CC1OC1P(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I14 compound treatment 271875.0 2260.0 0.05 259030.0 -6300.0 -0.13 -0.0604 -0.4344 1005991 SPBio_000812 O=C1c2ccccc2-c3cccc4cccc1c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I15 compound treatment 49195.0 -220000.0 -4.47 63276.0 -202000.0 -4.21 -6.1362 -0.9996 1191 SPBio_000813 Oc1c(Cl)cc(Cl)c2cccnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I16 compound treatment 254973.0 -14600.0 -0.3 256891.0 -8440.0 -0.18 -0.3342 -0.9688 2777 SPBio_000814 COc1cc(N)c(Cl)cc1C(=O)NC2CCN(Cc3ccccc3)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I17 compound treatment 279615.0 10000.0 0.2 307962.0 42600.0 0.89 0.7714 0.8468 3172720 SPBio_000815 CNC(C)[C@@H]1CC[C@@H](N)[C@@H](OC2[C@@H](N)C[C@@H](N)[C@H](OC3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I18 compound treatment 261823.0 -7790.0 -0.16 294614.0 29300.0 0.61 0.3197 0.5073 1294 SPBio_000816 CCN(CC)Cc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I19 compound treatment 249531.0 -20100.0 -0.41 314905.0 49600.0 1.03 0.4424 0.3985 927 SPBio_000817 CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I20 compound treatment 166237.0 -103000.0 -2.1 142195.0 -123000.0 -2.57 -3.2959 -0.995 1092 SPBio_000818 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I21 compound treatment 273460.0 3850.0 0.08 295804.0 30500.0 0.63 0.504 0.7881 1019607 SPBio_000819 CN(C)Cc1c(C)[nH]c2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I22 compound treatment 275299.0 5690.0 0.12 283593.0 18300.0 0.38 0.3505 0.8818 446 SPBio_000820 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I23 mock treatment 264301.0 -5310.0 -0.11 262044.0 -3290.0 -0.07 -0.1246 -0.9762 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 I24 mock treatment 268061.0 -1550.0 -0.03 266474.0 1140.0 0.02 -0.0054 -0.138 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J01 mock treatment 280375.0 10800.0 0.22 263082.0 -2250.0 -0.05 0.1211 0.5427 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J02 mock treatment 278137.0 8520.0 0.17 278797.0 13500.0 0.28 0.3205 0.9729 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J03 compound treatment 92388.0 -177000.0 -3.59 97540.0 -168000.0 -3.5 -5.0123 -0.9999 1175 SPBio_000821 Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J04 compound treatment 323652.0 54000.0 1.1 331102.0 65800.0 1.37 1.7435 0.9939 3172714 SPBio_000822 C[n+]1ccccc1/C=N/O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J05 compound treatment 299416.0 29800.0 0.6 337988.0 72700.0 1.51 1.4975 0.9189 856 SPBio_000823 Cn1c(=O)n(C)c2nc[nH]c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J06 compound treatment 339043.0 69400.0 1.41 351712.0 86400.0 1.8 2.2677 0.9926 1000105 SPBio_000824 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J07 compound treatment 205652.0 -64000.0 -1.3 259640.0 -5690.0 -0.12 -1.0007 -0.7686 1000127 SPBio_000825 CC1(C)O[C@@H]2CC3C4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J08 compound treatment 2722.0 -267000.0 -5.41 2214.0 -263000.0 -5.48 -7.7019 -1.0 3471036 SPBio_000826 OC(=O)C1=C(C[n+]2ccccc2)CSC3C(NC(=O)Cc4cccs4)C(=O)N31 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J09 compound treatment 309942.0 40300.0 0.82 324032.0 58700.0 1.22 1.4428 0.9808 1053 SPBio_000827 COc1cc(cc(OC)c1OC)C(=O)NCc2ccc(OCCN(C)C)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J10 compound treatment 312038.0 42400.0 0.86 295864.0 30500.0 0.64 1.0579 0.989 1338 SPBio_000828 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J11 compound treatment 281622.0 12000.0 0.24 267757.0 2420.0 0.05 0.2079 0.836 938 SPBio_000829 Cc1ccc(cc1)/C(=C\CN2CCCC2)/c3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J12 compound treatment 319561.0 49900.0 1.01 288206.0 22900.0 0.48 1.053 0.9409 1107 SPBio_000830 OC(=O)CN1CCNC1=N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J13 compound treatment 299098.0 29500.0 0.6 303810.0 38500.0 0.8 0.9895 0.9896 1146 SPBio_000831 Nc1ccc(cc1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J14 compound treatment 267564.0 -2050.0 -0.04 286098.0 20800.0 0.43 0.2765 0.6363 1271 SPBio_000832 CC(=O)OC(CC(=O)O)[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J15 compound treatment 5996.0 -264000.0 -5.34 6168.0 -259000.0 -5.4 -7.5968 -1.0 721 SPBio_000833 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@H](C)C[C@]4(CO4)C(=O)[C@H](C)[C@@H](O)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J16 compound treatment 271358.0 1750.0 0.04 238976.0 -26400.0 -0.55 -0.3633 -0.6602 1142 SPBio_000834 Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J17 compound treatment 321304.0 51700.0 1.05 285706.0 20400.0 0.42 1.0411 0.9208 2060131 SPBio_000835 CCOC(=O)c1oc2c(OC)c(O)cc(O)c2c(=O)c1c3cc(OC)c(OC)c(OC)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J18 compound treatment 306638.0 37000.0 0.75 316125.0 50800.0 1.06 1.279 0.9859 725 SPBio_000836 CC(=C)[C@@H]1CCC(=CC1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J19 compound treatment 304297.0 34700.0 0.7 279618.0 14300.0 0.3 0.7076 0.9268 3044782 SPBio_000837 NC(=N)N.OC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J20 compound treatment 322541.0 52900.0 1.07 318313.0 53000.0 1.1 1.5392 0.9999 1372 SPBio_000838 OC(=O)c1cccnc1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J21 compound treatment 324659.0 55000.0 1.12 268843.0 3510.0 0.07 0.8408 0.7518 1429 SPBio_000839 CCCCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J22 compound treatment 261815.0 -7800.0 -0.16 273896.0 8560.0 0.18 0.0144 0.0602 937 SPBio_000840 CCC(=O)c1ccc2Sc3ccccc3N(CC(C)N(C)C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J23 mock treatment 281278.0 11700.0 0.24 286845.0 21500.0 0.45 0.4841 0.9554 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 J24 mock treatment 253858.0 -15800.0 -0.32 234536.0 -30800.0 -0.64 -0.6795 -0.9481 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K01 mock treatment 247162.0 -22500.0 -0.46 249264.0 -16100.0 -0.33 -0.5585 -0.9886 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K02 mock treatment 277325.0 7710.0 0.16 288334.0 23000.0 0.48 0.4494 0.8916 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K03 compound treatment 257438.0 -12200.0 -0.25 320683.0 55300.0 1.15 0.6408 0.5434 3054976 SPBio_000841 CC(C)[C@@H]1CC[C@@H](C)CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K04 compound treatment 319750.0 50100.0 1.02 335774.0 70400.0 1.47 1.7564 0.9839 3173242 SPBio_000842 Nc1nc2cc(Cl)ccc2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K05 compound treatment 317247.0 47600.0 0.97 293528.0 28200.0 0.59 1.0982 0.9716 2060306 SPBio_000843 C[C@@H](CCOC(=O)C)CCC=C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K06 compound treatment 283839.0 14200.0 0.29 266031.0 697.0 0.01 0.2142 0.7418 2060291 SPBio_000844 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K07 compound treatment 331060.0 61400.0 1.25 302233.0 36900.0 0.77 1.4244 0.9731 3235 SPBio_000845 OC(=O)c1ccccc1OC(=O)c2ccccc2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K08 compound treatment 281797.0 12200.0 0.25 294270.0 28900.0 0.6 0.6009 0.9224 1156 SPBio_000846 OC(=O)c1cc(O)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K09 compound treatment 26060.0 -244000.0 -4.94 16662.0 -249000.0 -5.18 -7.1546 -0.9997 3177523 SPBio_000847 CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O)[C@H](C)O2)N(C)C)c3c(O)c4C(=O)c5c(O)ccc(O)c5C(=O)c4cc3[C@H]1C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K10 compound treatment 295765.0 26200.0 0.53 277551.0 12200.0 0.25 0.5549 0.9435 1308020 SPBio_000848 COc1ccc(cc1)c2cc(=O)c3ccccc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K11 compound treatment 262930.0 -6680.0 -0.14 221453.0 -43900.0 -0.91 -0.7422 -0.8031 1056 SPBio_000849 Nc1nc2nc[nH]c2c(=S)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K12 compound treatment 329350.0 59700.0 1.21 280585.0 15300.0 0.32 1.081 0.8634 1599 SPBio_000850 C=CCc1ccc2OCOc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K13 compound treatment 45553.0 -224000.0 -4.54 3474.0 -262000.0 -5.46 -7.0694 -0.9959 999 SPBio_000851 CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K14 compound treatment 314818.0 45200.0 0.92 295013.0 29700.0 0.62 1.0852 0.9816 3058468 SPBio_000852 COc1ccc(OC)c(c1)C(O)C(C)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K15 compound treatment 2845.0 -267000.0 -5.41 2565.0 -263000.0 -5.47 -7.695 -1.0 1356 SPBio_000853 Oc1cccc2cccnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K16 compound treatment 305487.0 35900.0 0.73 323618.0 58300.0 1.21 1.3729 0.97 2553 SPBio_000854 CNNC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K17 compound treatment 4034.0 -266000.0 -5.38 4657.0 -261000.0 -5.43 -7.6471 -1.0 3198320 SPBio_000855 Clc1ccc(CO/N=C(\Cn2ccnc2)/c3ccc(Cl)cc3Cl)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K18 compound treatment 230331.0 -39300.0 -0.8 262361.0 -2970.0 -0.06 -0.6069 -0.7598 422 SPBio_000856 Oc1cccc2C(=O)C=CC(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K19 compound treatment 284643.0 15000.0 0.3 314451.0 49100.0 1.02 0.939 0.8795 3047 SPBio_000857 C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)C(=C3[C@H]2OC1=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K20 compound treatment 290679.0 21100.0 0.43 278917.0 13600.0 0.28 0.5021 0.98 3198324 SPBio_000858 C[C@@H]1O[C@@H](OC[C@H]2OC(Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K21 compound treatment 298470.0 28900.0 0.59 348935.0 83600.0 1.74 1.6452 0.8955 1003215 SPBio_000859 CC(C)C1=CC(=O)C(=CC1=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K22 compound treatment 263215.0 -6400.0 -0.13 290944.0 25600.0 0.53 0.2856 0.5201 1330 SPBio_000860 ClCCN(CCCl)CCCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K23 mock treatment 312095.0 42500.0 0.86 280541.0 15200.0 0.32 0.833 0.9078 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 K24 mock treatment 305699.0 36100.0 0.73 287008.0 21700.0 0.45 0.8366 0.9731 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L01 mock treatment 306711.0 37100.0 0.75 285993.0 20700.0 0.43 0.8362 0.9649 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L02 mock treatment 303678.0 34100.0 0.69 298628.0 33300.0 0.69 0.9788 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L03 compound treatment 330733.0 61100.0 1.24 332461.0 67100.0 1.4 1.865 0.9982 930 SPBio_000861 CC(CN1CCCCC1)C(=O)c2ccc(C)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L04 compound treatment 330716.0 61100.0 1.24 306890.0 41600.0 0.87 1.4881 0.9847 1325 SPBio_000862 NC1(CCCC1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L05 compound treatment 318911.0 49300.0 1.0 348508.0 83200.0 1.73 1.932 0.9658 2576 SPBio_000863 S=C=NCc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L06 compound treatment 325455.0 55800.0 1.13 275183.0 9850.0 0.21 0.9456 0.8219 3173241 SPBio_000864 C[C@@]12CCC3C(CC[C@H]4C[C@@H](CC[C@@]43C)OS(=O)(=O)O)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L07 compound treatment 340269.0 70700.0 1.43 314661.0 49300.0 1.03 1.7395 0.9867 1099 SPBio_000865 CC(=O)NCCCCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L08 compound treatment 295237.0 25600.0 0.52 282435.0 17100.0 0.36 0.6193 0.9831 1266 SPBio_000866 CCn1cc(C(=O)O)c(=O)c2cc3OCOc3cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L09 compound treatment 286990.0 17400.0 0.35 332581.0 67200.0 1.4 1.2397 0.8582 850 SPBio_000867 Clc1cccc(c1)N2CCN(CCCn3nc4ccccn4c3=O)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L10 compound treatment 325137.0 55500.0 1.13 327198.0 61900.0 1.29 1.7073 0.9977 1081 SPBio_000868 Cc1c(N)c(=O)n(c2ccccc2)n1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L11 compound treatment 312357.0 42700.0 0.87 341245.0 75900.0 1.58 1.731 0.9599 1413 SPBio_000869 CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L12 compound treatment 301600.0 32000.0 0.65 307440.0 42100.0 0.88 1.0788 0.9889 1000116 SPBio_000870 CC(=O)CC(c1ccccc1)c2c(O)c3ccccc3oc2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L13 compound treatment 355090.0 85500.0 1.73 348566.0 83200.0 1.73 2.4514 1.0 1433 SPBio_000871 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L14 compound treatment 304290.0 34700.0 0.7 295819.0 30500.0 0.64 0.9462 0.9987 1075 SPBio_000872 CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L15 compound treatment 307135.0 37500.0 0.76 280525.0 15200.0 0.32 0.7617 0.9245 801 SPBio_000873 CN(C)CC/C=C/1\c2ccccc2Sc3ccc(Cl)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L16 compound treatment 2965.0 -267000.0 -5.41 2614.0 -263000.0 -5.47 -7.6926 -1.0 1201 SPBio_000874 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L17 compound treatment 302257.0 32600.0 0.66 304725.0 39400.0 0.82 1.0482 0.9943 1278 SPBio_000875 COc1ccc(cc1O)c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@H](C)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L18 compound treatment 283236.0 13600.0 0.28 265901.0 567.0 0.01 0.2037 0.7367 1061 SPBio_000876 Nc1nc(N)c2nc(c(N)nc2n1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L19 compound treatment 304906.0 35300.0 0.72 305171.0 39800.0 0.83 1.0928 0.9973 3177517 SPBio_000877 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)C(O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L20 compound treatment 311722.0 42100.0 0.85 318634.0 53300.0 1.11 1.3888 0.9916 1341 SPBio_000878 CC(=O)OCC(COC(=O)C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L21 compound treatment 286531.0 16900.0 0.34 294917.0 29600.0 0.62 0.6783 0.9617 1162 SPBio_000879 Cc1c(NC(=O)c2cccnc2)c(=O)n(c3ccccc3)n1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L22 compound treatment 303667.0 34100.0 0.69 298115.0 32800.0 0.68 0.9711 1.0 3173364 SPBio_000880 C[C@H]1[C@@]2(C)CCC3C(CCC4C[C@H](CC[C@@]43C)O[C@H]5O[C@H](CO)[C@H](O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O[C@H]7OC[C@@H](O)[C@H](O)[C@H]7O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H]6O)[C@H](O)[C@H]5O)C2O[C@]91CC[C@H](C)CN9 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L23 mock treatment 303687.0 34100.0 0.69 286968.0 21600.0 0.45 0.8072 0.9786 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 L24 mock treatment 313812.0 44200.0 0.9 261685.0 -3650.0 -0.08 0.5799 0.6448 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M01 mock treatment 231406.0 -38200.0 -0.77 269036.0 3700.0 0.08 -0.4931 -0.6336 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M02 mock treatment 295041.0 25400.0 0.52 244357.0 -21000.0 -0.44 0.0555 0.0821 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M03 compound treatment 272703.0 3090.0 0.06 261795.0 -3540.0 -0.07 -0.0078 -0.0808 3174245 SPBio_000881 OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M04 compound treatment 66635.0 -203000.0 -4.11 81146.0 -184000.0 -3.84 -5.623 -0.9994 1019365 SPBio_000882 COC1=CC(=O)C=C(OC)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M05 compound treatment 307099.0 37500.0 0.76 340851.0 75500.0 1.57 1.6498 0.9443 2060246 SPBio_000883 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C/C=C/3\[C@H](O)COC3=O)C(=C)CCC12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M06 compound treatment 307333.0 37700.0 0.76 300950.0 35600.0 0.74 1.0654 0.9999 2081029 SPBio_000884 CN/C(=N\C#N)/NCCSCc1nc[nH]c1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M07 compound treatment 291736.0 22100.0 0.45 304559.0 39200.0 0.82 0.895 0.9601 907310 SPBio_000885 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M08 compound treatment 27861.0 -242000.0 -4.9 60045.0 -205000.0 -4.28 -6.4897 -0.9977 2060352 SPBio_000886 O=C(O[C@H]1Cc2c(OC(=O)c3ccccc3)cc(OC(=O)c4ccccc4)cc2O[C@@H]1c5ccc(OC(=O)c6ccccc6)c(OC(=O)c7ccccc7)c5)c8ccccc8 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M09 compound treatment 282437.0 12800.0 0.26 249894.0 -15400.0 -0.32 -0.0436 -0.1054 3057880 SPBio_000887 COc1ccc(cc1)C(=C(c2ccc(OC)cc2)c3ccc(OC)cc3)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M10 compound treatment 304506.0 34900.0 0.71 305026.0 39700.0 0.83 1.0849 0.997 847 SPBio_000888 CC(=CCC/C(=C/CO)/C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M11 compound treatment 298884.0 29300.0 0.59 280993.0 15700.0 0.33 0.6503 0.9603 3060195 SPBio_000889 COC(C)(C)CCC[C@H](C)C/C=C/C(=C/C(=O)OC(C)C)/C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M12 compound treatment 284284.0 14700.0 0.3 304019.0 38700.0 0.81 0.7802 0.9082 1029 SPBio_000890 CC(C(=O)O)c1ccc(cc1)N2Cc3ccccc3C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M13 compound treatment 2665.0 -267000.0 -5.41 5943.0 -259000.0 -5.4 -7.6478 -1.0 3173342 SPBio_000891 CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)O)COC(=O)N)\c3ccco3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M14 compound treatment 129535.0 -140000.0 -2.84 112028.0 -153000.0 -3.19 -4.2664 -0.9983 784 SPBio_000892 Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M15 compound treatment 278914.0 9300.0 0.19 256478.0 -8860.0 -0.18 0.0029 0.0109 370 SPBio_000893 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M16 compound treatment 278895.0 9280.0 0.19 288962.0 23600.0 0.49 0.4811 0.913 1195 SPBio_000894 C[C@@]12CCC3C(CC[C@]4(O)C[C@@H](O)CC[C@]34C=O)[C@@]2(O)CCC1C5=CC(=O)OC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M17 compound treatment 4600.0 -265000.0 -5.37 3572.0 -262000.0 -5.45 -7.655 -1.0 3198321 SPBio_000895 CCCCCCCC/C=C/CCCCCCCCOP(=O)(O)OCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M18 compound treatment 16327.0 -253000.0 -5.13 13222.0 -252000.0 -5.25 -7.3448 -0.9999 1256 SPBio_000896 Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M19 compound treatment 156709.0 -113000.0 -2.29 267129.0 1800.0 0.04 -1.592 -0.6955 1713087 SPBio_000897 COc1ccc(cc1OC)c2cc(=O)c3ccccc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M20 compound treatment 316271.0 46700.0 0.95 300293.0 35000.0 0.73 1.1838 0.9917 41 SPBio_000898 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M21 compound treatment 259850.0 -9760.0 -0.2 296230.0 30900.0 0.64 0.3152 0.4681 3058622 SPBio_000899 OC1=CC2=C3c4ccc(O)cc4OC[C@]3(O)CC2=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M22 compound treatment 255316.0 -14300.0 -0.29 310064.0 44700.0 0.93 0.454 0.4652 2060048 SPBio_000900 CC(=O)c1c(O)c(C)c(O)c2c1oc3c(C(=O)C)c(O)c(C)c(O)c32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M23 mock treatment 278195.0 8580.0 0.17 275083.0 9750.0 0.2 0.2667 0.997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 M24 mock treatment 268099.0 -1510.0 -0.03 265275.0 -58.5 0.0 -0.0226 -0.7346 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N01 mock treatment 292881.0 23300.0 0.47 317087.0 51800.0 1.08 1.0959 0.9312 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N02 mock treatment 352439.0 82800.0 1.68 312243.0 46900.0 0.98 1.8784 0.9668 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N03 compound treatment 290137.0 20500.0 0.42 327854.0 62500.0 1.3 1.2152 0.8888 860 SPBio_000901 CN(C)C(=O)Oc1ccc[n+](C)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N04 compound treatment 306040.0 36400.0 0.74 343857.0 78500.0 1.64 1.6789 0.9354 2407 SPBio_000902 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ncc(C)s3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N05 compound treatment 302255.0 32600.0 0.66 316350.0 51000.0 1.06 1.2195 0.974 1268 SPBio_000903 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3cc(C)on3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N06 compound treatment 383264.0 114000.0 2.3 290182.0 24800.0 0.52 1.9953 0.8449 811 SPBio_000904 CC(=O)[C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N07 compound treatment 352000.0 82400.0 1.67 346468.0 81100.0 1.69 2.3762 1.0 1100 SPBio_000905 CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N08 compound treatment 2567.0 -267000.0 -5.41 2778.0 -263000.0 -5.47 -7.6959 -1.0 928 SPBio_000906 CC(=O)O[Hg]c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N09 compound treatment 7388.0 -262000.0 -5.32 8922.0 -256000.0 -5.34 -7.5362 -1.0 3173346 SPBio_000907 CC[C@H](C1OC(CC)(C[C@@H]1C)C2CC[C@](O)(CC)[C@H](C)O2)C(=O)C(C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N10 compound treatment 235701.0 -33900.0 -0.69 236616.0 -28700.0 -0.6 -0.9092 -0.9976 1374 SPBio_000908 Oc1c(Br)cc(Br)c2cccnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N11 compound treatment 315348.0 45700.0 0.93 314498.0 49200.0 1.02 1.3799 0.9988 1274 SPBio_000909 C1CN2C[C@@H](N=C2S1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N12 compound treatment 311147.0 41500.0 0.84 301641.0 36300.0 0.76 1.1303 0.9986 816 SPBio_000910 Cc1cc(cc(C)c1CC2=NCCN2)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N13 compound treatment 277067.0 7450.0 0.15 293248.0 27900.0 0.58 0.5181 0.8622 1232 SPBio_000911 OC1=C(O)C(=O)C(=C(O)C1=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N14 compound treatment 303947.0 34300.0 0.7 294269.0 28900.0 0.6 0.9184 0.9974 471 SPBio_000912 CCCC(CCC)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N15 compound treatment 2382.0 -267000.0 -5.42 2589.0 -263000.0 -5.47 -7.7013 -1.0 1051 SPBio_000913 CC(=O)Oc1ccc(Cl)c2cccnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N16 compound treatment 252970.0 -16600.0 -0.34 303268.0 37900.0 0.79 0.3202 0.3727 1044 SPBio_000914 C[C@H](CCC(=O)O)[C@H]1CCC2C3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N17 compound treatment 300323.0 30700.0 0.62 280845.0 15500.0 0.32 0.6687 0.9534 975 SPBio_000915 CCN(CC)CCOC(=O)C(CC1CCCO1)Cc2cccc3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N18 compound treatment 308099.0 38500.0 0.78 266247.0 913.0 0.02 0.5652 0.7241 1000 SPBio_000916 NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N19 compound treatment 294936.0 25300.0 0.51 304184.0 38900.0 0.81 0.9353 0.9759 798 SPBio_000917 CCCCCCOc1ccccc1C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N20 compound treatment 265763.0 -3850.0 -0.08 270463.0 5130.0 0.11 0.0204 0.154 977 SPBio_000918 C[C@@]12C[C@H](O)[C@@]3(F)C(CCC4=CC(=O)C=C[C@@]43C)C2C[C@@H](O)[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N21 compound treatment 276732.0 7120.0 0.14 295821.0 30500.0 0.64 0.5512 0.8462 1000115 SPBio_000919 COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N22 compound treatment 201919.0 -67700.0 -1.37 232714.0 -32600.0 -0.68 -1.4509 -0.9475 971 SPBio_000920 CN(C(=S)Oc1ccc2ccccc2c1)c3cccc(C)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N23 mock treatment 245315.0 -24300.0 -0.49 288883.0 23500.0 0.49 -0.0014 -0.002 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 N24 mock treatment 266973.0 -2640.0 -0.05 262241.0 -3090.0 -0.06 -0.0834 -0.9957 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O01 mock treatment 226918.0 -42700.0 -0.87 251777.0 -13600.0 -0.28 -0.8117 -0.8916 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O02 mock treatment 250034.0 -19600.0 -0.4 250878.0 -14500.0 -0.3 -0.4936 -0.9907 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O03 compound treatment 274949.0 5340.0 0.11 276692.0 11400.0 0.24 0.2438 0.9371 1053058 SPBio_000921 COc1cc(OC)c2c(=O)c(O)c(oc2c1)c3ccc(OC)c(OC)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O04 compound treatment 277320.0 7710.0 0.16 287317.0 22000.0 0.46 0.4343 0.8976 1003514 SPBio_000922 COc1cc(cc(OC)c1OC)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O05 compound treatment 2560.0 -267000.0 -5.41 2798.0 -263000.0 -5.47 -7.6957 -1.0 3055171 SPBio_000923 COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CCc5c(C)c(O)c(O)cc5[C@]4(C)CC[C@@]3(C)C2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O06 compound treatment 297945.0 28300.0 0.57 280906.0 15600.0 0.32 0.6356 0.9634 2060483 SPBio_000924 CC(=O)N[C@@H](CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O07 compound treatment 293416.0 23800.0 0.48 290524.0 25200.0 0.52 0.7123 0.9991 2069289 SPBio_000925 CC(=O)Oc1cc2c(CC3OC34[C@@]2(C)CC[C@@]5(C)C6C[C@@](C)(CC[C@]6(C)CC[C@]45C)C(=O)O)c(C)c1OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O08 compound treatment 308015.0 38400.0 0.78 273509.0 8180.0 0.17 0.6709 0.8419 3078273 SPBio_000926 COc1cc(C)c(C(=O)Oc2cc(C)c(O)c(C(=O)O)c2C)c(O)c1C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O09 compound treatment 204924.0 -64700.0 -1.31 222939.0 -42400.0 -0.88 -1.5518 -0.9815 3198322 SPBio_000927 CC1CNC(=O)CCC2(C)C(CC(=O)N)C3N4C2=C(C)C5=N6C(=CC7=N8C(=C(C)C9=N(C3(C)C(C)(CC(=O)N)C9CCC(=O)N)[Co+]486(C[C@H]%10OC([C@H](O)[C@@H]%10O)n%11cnc%12c(N)ncnc%11%12)N%13=CN(C%14O[C@H](CO)[C@@H](OP(=O)(O)O1)[C@H]%14O)c%15cc(C)c(C)cc%13%15)C(C)(CC(=O)N)C7CCC(=O)N)C(C)(C)C5CCC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O10 compound treatment 293374.0 23800.0 0.48 273372.0 8040.0 0.17 0.459 0.9001 112 SPBio_000928 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O11 compound treatment 295582.0 26000.0 0.53 289461.0 24100.0 0.5 0.7277 0.9997 1538 SPBio_000929 Oc1ccc(c(O)c1)c2oc3cc(O)cc(O)c3c(=O)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O12 compound treatment 302338.0 32700.0 0.66 305989.0 40700.0 0.85 1.068 0.9927 3198325 SPBio_000930 COc1ccc(cc1)c2cc(=O)c3c(OC)cc(O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O13 compound treatment 281690.0 12100.0 0.24 271465.0 6130.0 0.13 0.2635 0.954 1343 SPBio_000931 COC1=CC(C)[C@@H]2C[C@H]3OC(=O)C[C@H]4C(=C(OC)C(=O)C([C@@]34C)[C@@]2(C)C1=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O14 compound treatment 260466.0 -9150.0 -0.19 288792.0 23500.0 0.49 0.2145 0.4103 2080198 SPBio_000932 CC(=O)C1=C(O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O15 compound treatment 262581.0 -7030.0 -0.14 262233.0 -3100.0 -0.06 -0.1465 -0.9359 2069234 SPBio_000933 CN1CCc2cc3OCOc3cc2[C@H]1C4OC(=O)c5c6OCOc6ccc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O16 compound treatment 266319.0 -3290.0 -0.07 281739.0 16400.0 0.34 0.1945 0.5584 1353 SPBio_000934 COC(=O)/C(=C/1\OC(=O)C(C1=O)c2ccccc2)/c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O17 compound treatment 247015.0 -22600.0 -0.46 227470.0 -37900.0 -0.79 -0.8817 -0.9666 3078269 SPBio_000935 OCC(O)CC(O)CCCCCCCCCCCC=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O18 compound treatment 294642.0 25000.0 0.51 283977.0 18600.0 0.39 0.6334 0.9913 2060168 SPBio_000936 C/C(=C/CC1[C@](C)(O)CC[C@H]2C(C)(C)CCC[C@]12C)/C=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O19 compound treatment 278595.0 8980.0 0.18 267819.0 2490.0 0.05 0.1654 0.8735 1000122 SPBio_000937 O[C@@H]([C@@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O20 compound treatment 169626.0 -100000.0 -2.03 200729.0 -64600.0 -1.35 -2.385 -0.9802 1576 SPBio_000938 CC(=CCc1c(O)c2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc(O)c(O)c4)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O21 compound treatment 248997.0 -20600.0 -0.42 296804.0 31500.0 0.66 0.1681 0.2162 1601 SPBio_000939 COc1c(OC)c2ccc(=O)oc2c3ccoc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O22 compound treatment 277638.0 8030.0 0.16 249646.0 -15700.0 -0.33 -0.116 -0.3179 994 SPBio_000940 N[C@@H](CCONC(=N)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O23 mock treatment 260633.0 -8980.0 -0.18 253513.0 -11800.0 -0.25 -0.3028 -0.9889 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 O24 mock treatment 253971.0 -15600.0 -0.32 268625.0 3290.0 0.07 -0.1757 -0.5417 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P01 mock treatment 249293.0 -20300.0 -0.41 265288.0 -45.5 0.0 -0.292 -0.7087 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P02 mock treatment 246940.0 -22700.0 -0.46 293373.0 28000.0 0.58 0.088 0.1184 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P03 compound treatment 301334.0 31700.0 0.64 300317.0 35000.0 0.73 0.9701 0.9981 1000112 SPBio_000941 CC(=O)O[C@H]1[C@@H](O)C2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P04 compound treatment 307534.0 37900.0 0.77 300400.0 35100.0 0.73 1.0602 0.9997 1000129 SPBio_000942 CC1(C)[C@H](CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O)OC(=O)CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P05 compound treatment 301193.0 31600.0 0.64 283193.0 17900.0 0.37 0.7158 0.9667 1000045 SPBio_000943 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P06 compound treatment 205584.0 -64000.0 -1.3 209414.0 -55900.0 -1.16 -1.7416 -0.9985 1004 SPBio_000944 Oc1ccc2c(=O)cc(oc2c1O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P07 compound treatment 305315.0 35700.0 0.72 297373.0 32000.0 0.67 0.9838 0.9992 1450 SPBio_000945 NCCc1c[nH]c2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P08 compound treatment 306071.0 36500.0 0.74 300159.0 34800.0 0.73 1.0357 1.0 922 SPBio_000946 CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P09 compound treatment 249462.0 -20200.0 -0.41 259189.0 -6140.0 -0.13 -0.3794 -0.8862 1586 SPBio_000947 NCCCCNCCCN 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P10 compound treatment 278636.0 9020.0 0.18 286565.0 21200.0 0.44 0.4421 0.9237 1106 SPBio_000948 CCC(=O)c1c(O)cc(O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P11 compound treatment 264550.0 -5060.0 -0.1 257490.0 -7840.0 -0.16 -0.1881 -0.9749 831758 SPBio_000949 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P12 compound treatment 272023.0 2410.0 0.05 302845.0 37500.0 0.78 0.5871 0.7499 1533 SPBio_000950 Cc1cc(CC(=O)O)n(C)c1C(=O)c2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P13 compound treatment 263614.0 -6000.0 -0.12 261702.0 -3630.0 -0.08 -0.1395 -0.9739 1898 SPBio_000951 OC(=O)CC[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P14 compound treatment 261460.0 -8150.0 -0.17 266123.0 789.0 0.02 -0.1052 -0.6336 1209 SPBio_000952 CC(C(=O)O)c1cccc(c1)C(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P15 compound treatment 247094.0 -22500.0 -0.46 254690.0 -10600.0 -0.22 -0.4796 -0.945 1089854 SPBio_000953 Cc1ncc(CNC(=O)N(CCCl)N=O)c(N)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P16 compound treatment 245601.0 -24000.0 -0.49 294899.0 29600.0 0.62 0.0913 0.1163 1152 SPBio_000954 CN(C)CCN(Cc1ccccc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P17 compound treatment 248891.0 -20700.0 -0.42 258275.0 -7060.0 -0.15 -0.401 -0.901 1001531 SPBio_000955 COc1cc(cc(OC)c1OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](O)c4cc5OCOc5cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P18 compound treatment 217153.0 -52500.0 -1.06 222624.0 -42700.0 -0.89 -1.3812 -0.9961 3044756 SPBio_000956 CC(CN(C)C)CN1c2ccccc2Sc3ccccc13.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P19 compound treatment 253745.0 -15900.0 -0.32 256269.0 -9060.0 -0.19 -0.361 -0.9678 831 SPBio_000957 Nc1nccs1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P20 compound treatment 240961.0 -28700.0 -0.58 242490.0 -22800.0 -0.48 -0.7472 -0.9951 1000123 SPBio_000958 CC(=O)OCC(=O)[C@@]1(O)[C@@H](CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P21 compound treatment 280166.0 10600.0 0.21 231357.0 -34000.0 -0.71 -0.3492 -0.4723 1249 SPBio_000959 C[N+](C)(C)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P22 compound treatment 259555.0 -10100.0 -0.2 223804.0 -41500.0 -0.87 -0.7559 -0.8504 1200 SPBio_000960 NC1C[C@H]1c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P23 mock treatment 252725.0 -16900.0 -0.34 224493.0 -40800.0 -0.85 -0.8437 -0.9199 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2160 P24 mock treatment 255403.0 -14200.0 -0.29 257328.0 -8010.0 -0.17 -0.3216 -0.9662 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A01 mock treatment 226449.0 -40800.0 -0.83 209312.0 -54000.0 -1.12 -1.3799 -0.9886 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A02 mock treatment 216710.0 -50500.0 -1.02 279760.0 16500.0 0.34 -0.4817 -0.4458 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A03 compound treatment 257623.0 -9620.0 -0.2 256350.0 -6930.0 -0.14 -0.2401 -0.9891 1002 SPBio_000961 CN(C)CCOC(c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A04 compound treatment 285725.0 18500.0 0.37 317056.0 53800.0 1.12 1.0571 0.8949 778 SPBio_000962 Oc1c(I)cc(I)c2cccnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A05 compound treatment 2599.0 -265000.0 -5.37 2297.0 -261000.0 -5.44 -7.6383 -1.0 979 SPBio_000963 S=C1CC=CC=N1O[Zn]On2ccccc2=S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A06 compound treatment 278758.0 11500.0 0.23 271645.0 8360.0 0.17 0.2882 0.9896 1244 SPBio_000964 C[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A07 compound treatment 282721.0 15500.0 0.31 239377.0 -23900.0 -0.5 -0.1303 -0.2214 1216 SPBio_000965 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2C[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A08 compound treatment 247401.0 -19800.0 -0.4 218549.0 -44700.0 -0.93 -0.9434 -0.9294 890 SPBio_000966 COc1ccc2cc(ccc2c1)[C@H](C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A09 compound treatment 262072.0 -5170.0 -0.1 270988.0 7710.0 0.16 0.0394 0.2053 3177385 SPBio_000967 CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A10 compound treatment 237554.0 -29700.0 -0.6 254635.0 -8650.0 -0.18 -0.553 -0.8802 1406 SPBio_000968 NC(=O)c1cc(cc(c1)[N+](=O)[O-])[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A11 compound treatment 269017.0 1770.0 0.04 270898.0 7620.0 0.16 0.1376 0.8458 858 SPBio_000969 OCC(O)CN1CCN(CC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A12 compound treatment 310218.0 43000.0 0.87 300731.0 37400.0 0.78 1.1677 0.9985 1123 SPBio_000970 Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A13 compound treatment 235978.0 -31300.0 -0.63 288245.0 25000.0 0.52 -0.0805 -0.0982 827 SPBio_000971 CCCCC1(COC(=O)CCC(=O)O)C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A14 compound treatment 180090.0 -87200.0 -1.77 248743.0 -14500.0 -0.3 -1.4636 -0.8164 3173466 SPBio_000972 [O-][N+](=O)c1ccc(/C=N/N2CC(=O)NC2=O)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A15 compound treatment 277199.0 9950.0 0.2 240570.0 -22700.0 -0.47 -0.1919 -0.373 770 SPBio_000973 CC(CCc1ccccc1)NC(C)C(O)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A16 compound treatment 2604.0 -265000.0 -5.37 2607.0 -261000.0 -5.43 -7.6337 -1.0 1077 SPBio_000974 CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4c(ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A17 compound treatment 271923.0 4680.0 0.09 268631.0 5350.0 0.11 0.1459 0.9968 950 SPBio_000975 Oc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A18 compound treatment 45666.0 -222000.0 -4.49 45268.0 -218000.0 -4.54 -6.388 -1.0 814 SPBio_000976 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A19 compound treatment 268567.0 1320.0 0.03 285141.0 21900.0 0.46 0.341 0.7474 776 SPBio_000977 NNc1nncc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A20 compound treatment 239530.0 -27700.0 -0.56 218545.0 -44700.0 -0.93 -1.0563 -0.9706 3173600 SPBio_000978 Oc1ccc2C[C@H]3N(CC=C)CC[C@]4(C5Oc1c24)[C@@]3(O)CCC5=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A21 compound treatment 253707.0 -13500.0 -0.27 261139.0 -2140.0 -0.04 -0.2256 -0.8115 2797 SPBio_000979 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A22 compound treatment 253499.0 -13700.0 -0.28 245796.0 -17500.0 -0.36 -0.4546 -0.9912 404 SPBio_000980 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A23 mock treatment 240363.0 -26900.0 -0.54 229018.0 -34300.0 -0.71 -0.8901 -0.9911 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 A24 mock treatment 228996.0 -38200.0 -0.78 231149.0 -32100.0 -0.67 -1.0217 -0.9973 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B01 mock treatment 256953.0 -10300.0 -0.21 260086.0 -3200.0 -0.07 -0.1946 -0.8886 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B02 mock treatment 261102.0 -6140.0 -0.12 250886.0 -12400.0 -0.26 -0.2707 -0.9441 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B03 compound treatment 265125.0 -2120.0 -0.04 265580.0 2300.0 0.05 0.0035 0.0538 1008060 SPBio_000981 C1CCc2nnnn2CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B04 compound treatment 263335.0 -3910.0 -0.08 288492.0 25200.0 0.53 0.3153 0.5937 1086 SPBio_000982 CC(C)C(=O)Nc1ccc([N+](=O)[O-])c(c1)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B05 compound treatment 10031.0 -257000.0 -5.21 29148.0 -234000.0 -4.88 -7.1362 -0.9994 1221 SPBio_000983 CN(C)CCOC(=O)C(c1ccccc1)C2(O)CCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B06 compound treatment 298441.0 31200.0 0.63 318283.0 55000.0 1.15 1.2574 0.9608 1184 SPBio_000984 Nc1ncnc2n(cnc12)C3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B07 compound treatment 292066.0 24800.0 0.5 299795.0 36500.0 0.76 0.8937 0.9799 1058 SPBio_000985 C[C@@]12CCC3C(CCC4=Cc5oncc5C[C@]34C)C2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B08 compound treatment 297629.0 30400.0 0.62 240296.0 -23000.0 -0.48 0.0969 0.1243 1434 SPBio_000986 CN1CCN2C(C1)c3ccccc3Cc4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B09 compound treatment 280687.0 13400.0 0.27 274873.0 11600.0 0.24 0.3634 0.9982 1302 SPBio_000987 CC(C)CC1N2C(=O)[C@](NC(=O)C3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(OC2(O)[C@@H]7CCCN7C1=O)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B10 compound treatment 264028.0 -3220.0 -0.07 292103.0 28800.0 0.6 0.3784 0.6266 965 SPBio_000988 C(C1=NCCN1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B11 compound treatment 195512.0 -71700.0 -1.45 190565.0 -72700.0 -1.51 -2.0995 -0.9998 2060103 SPBio_000989 COc1ccc2C(=O)[C@@H]3[C@@H](COc4cc(OC)c(OC)cc34)Oc2c1CC=C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B12 compound treatment 284253.0 17000.0 0.34 277185.0 13900.0 0.29 0.4486 0.9962 865 SPBio_000990 Cc1ccc(cc1)C(=O)c2ccc(CC(=O)O)n2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B13 compound treatment 270874.0 3630.0 0.07 286083.0 22800.0 0.48 0.3879 0.807 3045298 SPBio_000991 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B14 compound treatment 255715.0 -11500.0 -0.23 270369.0 7090.0 0.15 -0.0609 -0.2202 1487 SPBio_000992 CCC(Cc1c(I)cc(I)c(N)c1I)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B15 compound treatment 287564.0 20300.0 0.41 262026.0 -1260.0 -0.03 0.2728 0.6608 1412 SPBio_000993 CN(C)CCOC(c1ccc(Cl)cc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B16 compound treatment 273688.0 6440.0 0.13 285201.0 21900.0 0.46 0.4152 0.8743 1322 SPBio_000994 COc1cc2ccc(=O)oc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B17 compound treatment 279800.0 12600.0 0.25 270712.0 7430.0 0.15 0.2894 0.9716 3198425 SPBio_000995 CC1(C)O[C@@H]2CO[C@@]3(COS(=O)(=O)N)OC(C)(C)O[C@H]3[C@@H]2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B18 compound treatment 282749.0 15500.0 0.31 264738.0 1460.0 0.03 0.2437 0.7717 1227 SPBio_000996 NCCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B19 compound treatment 272182.0 4940.0 0.1 276698.0 13400.0 0.28 0.2684 0.9041 775 SPBio_000997 NCC(O)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B20 compound treatment 239973.0 -27300.0 -0.55 246082.0 -17200.0 -0.36 -0.6443 -0.978 142 SPBio_000998 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B21 compound treatment 278182.0 10900.0 0.22 264421.0 1140.0 0.02 0.1736 0.7783 2069268 SPBio_000999 CC(=O)O[C@H]1CC[C@]2(C)C3CC[C@@]4(C)C(CCC4=O)C3CC=C2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B22 compound treatment 280757.0 13500.0 0.27 259221.0 -4060.0 -0.08 0.1339 0.4669 198 SPBio_001000 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B23 mock treatment 304917.0 37700.0 0.76 289399.0 26100.0 0.54 0.9248 0.9862 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 B24 mock treatment 239222.0 -28000.0 -0.57 236916.0 -26400.0 -0.55 -0.7901 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C01 mock treatment 254918.0 -12300.0 -0.25 249252.0 -14000.0 -0.29 -0.3834 -0.997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C02 mock treatment 282559.0 15300.0 0.31 242048.0 -21200.0 -0.44 -0.0933 -0.1726 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C03 compound treatment 57160.0 -210000.0 -4.26 71758.0 -192000.0 -3.99 -5.833 -0.9995 1370 SPBio_001001 C/C=C(/C(=C/C)/c1ccc(O)cc1)\c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C04 compound treatment 58823.0 -208000.0 -4.23 91052.0 -172000.0 -3.59 -5.5249 -0.9967 888 SPBio_001002 CC(C)[N+](C)(CCC(C(=O)N)(c1ccccc1)c2ccccc2)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C05 compound treatment 298353.0 31100.0 0.63 315967.0 52700.0 1.1 1.222 0.9654 1301 SPBio_001003 OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C06 compound treatment 186036.0 -81200.0 -1.65 198198.0 -65100.0 -1.36 -2.1229 -0.9954 1362 SPBio_001004 COc1c2occc2cc3ccc(=O)oc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C07 compound treatment 283578.0 16300.0 0.33 257438.0 -5840.0 -0.12 0.148 0.4196 1468 SPBio_001005 CCCCC(=O)O[C@H]1CCC2C3CCc4cc(O)ccc4C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C08 compound treatment 280667.0 13400.0 0.27 283471.0 20200.0 0.42 0.4898 0.9778 82 SPBio_001006 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C09 compound treatment 254311.0 -12900.0 -0.26 267005.0 3720.0 0.08 -0.1306 -0.4775 3177451 SPBio_001007 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C10 compound treatment 285957.0 18700.0 0.38 260718.0 -2560.0 -0.05 0.2305 0.6016 1083 SPBio_001008 C(C1=NCCN1)c2cccc3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C11 compound treatment 270699.0 3450.0 0.07 255380.0 -7900.0 -0.16 -0.0669 -0.3739 793 SPBio_001009 CCN(CC)CCOC(=O)C(C1CCCCC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C12 compound treatment 284150.0 16900.0 0.34 270862.0 7580.0 0.16 0.354 0.9381 953 SPBio_001010 C[C@H](N)[C@H](O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C13 compound treatment 295458.0 28200.0 0.57 272130.0 8850.0 0.18 0.5348 0.8899 826 SPBio_001011 CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)CC[C@]5(C)C4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C14 compound treatment 238643.0 -28600.0 -0.58 223649.0 -39600.0 -0.83 -0.9939 -0.985 1000108 SPBio_001012 NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C15 compound treatment 4959.0 -262000.0 -5.32 3771.0 -260000.0 -5.41 -7.5828 -1.0 905 SPBio_001013 CO[C@@H]1[C@@H](OC(=O)N)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C16 compound treatment 263997.0 -3250.0 -0.07 259751.0 -3530.0 -0.07 -0.0986 -0.9985 3173081 SPBio_001014 COCCc1ccc(OCC(O)CNC(C)C)cc1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C17 compound treatment 257774.0 -9470.0 -0.19 225214.0 -38100.0 -0.79 -0.6966 -0.8536 959 SPBio_001015 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C18 compound treatment 334084.0 66800.0 1.36 316792.0 53500.0 1.11 1.7464 0.9953 110 SPBio_001016 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C19 compound treatment 251292.0 -16000.0 -0.32 276010.0 12700.0 0.27 -0.0412 -0.0985 700 SPBio_001017 CN1C2CC[C@H]1C[C@H](C2)OC(=O)C(O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C20 compound treatment 245773.0 -21500.0 -0.44 247188.0 -16100.0 -0.34 -0.5449 -0.9917 3177386 SPBio_001018 NC[C@H]1O[C@H](OC2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C21 compound treatment 266339.0 -906.0 -0.02 265308.0 2030.0 0.04 0.0169 0.3662 1127 SPBio_001019 CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C22 compound treatment 243459.0 -23800.0 -0.48 246971.0 -16300.0 -0.34 -0.5813 -0.9853 1508 SPBio_001020 CSCCC(NC=O)C(=O)NC(C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C23 mock treatment 254968.0 -12300.0 -0.25 270065.0 6780.0 0.14 -0.0761 -0.2658 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 C24 mock treatment 242510.0 -24700.0 -0.5 232135.0 -31100.0 -0.65 -0.8134 -0.9919 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D01 mock treatment 257878.0 -9370.0 -0.19 263567.0 285.0 0.01 -0.1301 -0.6847 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D02 mock treatment 279004.0 11800.0 0.24 258053.0 -5230.0 -0.11 0.0915 0.3492 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D03 compound treatment 7991.0 -259000.0 -5.26 2387.0 -261000.0 -5.44 -7.5597 -0.9999 820 SPBio_001021 Oc1ccc(Cl)c2cccnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D04 compound treatment 301903.0 34700.0 0.7 305280.0 42000.0 0.87 1.1155 0.9941 861 SPBio_001022 C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D05 compound treatment 5334.0 -262000.0 -5.31 4027.0 -259000.0 -5.4 -7.5736 -1.0 1451 SPBio_001023 CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D06 compound treatment 265194.0 -2050.0 -0.04 266187.0 2900.0 0.06 0.0134 0.1824 3055445 SPBio_001024 CC(=O)OC(C)(C)[C@@H]1Cc2cc3ccc(=O)oc3cc2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D07 compound treatment 294734.0 27500.0 0.56 295525.0 32200.0 0.67 0.869 0.9957 1186 SPBio_001025 Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D08 compound treatment 274359.0 7110.0 0.14 276007.0 12700.0 0.27 0.2894 0.9591 3172849 SPBio_001026 CN1CCC[C@H]1c2cccnc2.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D09 compound treatment 286318.0 19100.0 0.39 265653.0 2370.0 0.05 0.3083 0.791 2060478 SPBio_001027 CNc1ccc(cc1)C(=O)CC(O)CCC(C)C2OC(=O)CC(O)CC(=O)CC(O)CC(O)CC(O)CC(O)CC3(O)CC(O)C(C(CC(O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/C2C)O3)C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D10 compound treatment 3248.0 -264000.0 -5.35 3502.0 -260000.0 -5.41 -7.6113 -1.0 1087 SPBio_001028 Oc1ccc(Cl)cc1Cc2cc(Cl)ccc2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D11 compound treatment 292247.0 25000.0 0.51 298606.0 35300.0 0.74 0.8788 0.9834 4480 SPBio_001029 CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D12 compound treatment 289727.0 22500.0 0.46 263015.0 -267.0 -0.01 0.3183 0.6984 1190 SPBio_001030 Nc1c2C(O)CCCc2nc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D13 compound treatment 276546.0 9300.0 0.19 249332.0 -14000.0 -0.29 -0.0722 -0.2083 682 SPBio_001031 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3C(=O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D14 compound treatment 264641.0 -2600.0 -0.05 269963.0 6680.0 0.14 0.0611 0.4104 1448 SPBio_001032 OC(=O)c1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D15 compound treatment 258859.0 -8390.0 -0.17 265134.0 1850.0 0.04 -0.0929 -0.5331 1446 SPBio_001033 OC(COc1cccc2oc(cc(=O)c12)C(=O)O)COc3cccc4oc(cc(=O)c34)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D16 compound treatment 248930.0 -18300.0 -0.37 263319.0 36.7 0.0 -0.262 -0.7056 705 SPBio_001034 CC(Cc1cccc(c1)C(F)(F)F)NCCOC(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D17 compound treatment 228633.0 -38600.0 -0.78 265160.0 1880.0 0.04 -0.5258 -0.6709 2069333 SPBio_001035 CC[C@H](/C=C/C(C)C1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D18 compound treatment 251720.0 -15500.0 -0.31 251744.0 -11500.0 -0.24 -0.3925 -0.9911 1577 SPBio_001036 OCC(S)CS 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D19 compound treatment 223752.0 -43500.0 -0.88 167268.0 -96000.0 -2.0 -2.0379 -0.9322 1088 SPBio_001037 CCN(CC)CCOc1ccc(cc1)/C(=C(\Cl)/c2ccccc2)/c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D20 compound treatment 260121.0 -7120.0 -0.14 258457.0 -4830.0 -0.1 -0.1732 -0.9843 3177322 SPBio_001038 CC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D21 compound treatment 277829.0 10600.0 0.21 304615.0 41300.0 0.86 0.7606 0.8571 689 SPBio_001039 Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C(=O)O)s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D22 compound treatment 309242.0 42000.0 0.85 318514.0 55200.0 1.15 1.4157 0.989 3174103 SPBio_001040 C/C/1=C\CC[C@@]2(C)OC2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D23 mock treatment 243033.0 -24200.0 -0.49 245931.0 -17400.0 -0.36 -0.6027 -0.9887 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 D24 mock treatment 262527.0 -4720.0 -0.1 225001.0 -38300.0 -0.8 -0.6316 -0.7863 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E01 mock treatment 246831.0 -20400.0 -0.41 268096.0 4810.0 0.1 -0.2217 -0.5207 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E02 mock treatment 265635.0 -1610.0 -0.03 242005.0 -21300.0 -0.44 -0.3365 -0.7571 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E03 compound treatment 3506.0 -264000.0 -5.35 2703.0 -261000.0 -5.43 -7.6193 -1.0 1265 SPBio_001041 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4c(Cl)cccc4Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E04 compound treatment 286005.0 18800.0 0.38 294068.0 30800.0 0.64 0.7224 0.9689 1479 SPBio_001042 CC(C)NCC(O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E05 compound treatment 315317.0 48100.0 0.97 279729.0 16400.0 0.34 0.9314 0.9016 1441 SPBio_001043 CN1CCC(CC1)OC(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E06 compound treatment 262767.0 -4480.0 -0.09 271145.0 7860.0 0.16 0.0516 0.2757 1009 SPBio_001044 C[N+]1(C)C2CC(CC1C3OC32)OC(=O)[C@@H](CO)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E07 compound treatment 2702.0 -265000.0 -5.36 3597.0 -260000.0 -5.41 -7.6177 -1.0 1363 SPBio_001045 CCOC(=O)CCC(=O)O[C@@H]1[C@H](C[C@@H](C)O[C@H]1O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E08 compound treatment 332157.0 64900.0 1.32 313640.0 50400.0 1.05 1.6723 0.9937 1000107 SPBio_001046 CC(=O)O[C@]1(CCC2C3CCC4=CC(=O)CC[C@@H]4C3CC[C@@]21C)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E09 compound treatment 301758.0 34500.0 0.7 281612.0 18300.0 0.38 0.7648 0.9594 727 SPBio_001047 CCN(CC)C(C)CN1c2ccccc2Sc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E10 compound treatment 289093.0 21800.0 0.44 301720.0 38400.0 0.8 0.8794 0.961 879 SPBio_001048 NC[C@H](O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E11 compound treatment 272879.0 5630.0 0.11 300799.0 37500.0 0.78 0.6334 0.8019 1222 SPBio_001049 Cn1cnc2n(C)c(=O)[nH]c(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E12 compound treatment 295719.0 28500.0 0.58 267532.0 4250.0 0.09 0.4708 0.8061 3173462 SPBio_001050 C[C@H](COc1ccccc1)N[C@@H](C)[C@H](O)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E13 compound treatment 193635.0 -73600.0 -1.49 119895.0 -143000.0 -2.99 -3.1675 -0.9486 706 SPBio_001051 Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E14 compound treatment 246275.0 -21000.0 -0.43 286427.0 23100.0 0.48 0.0403 0.0628 1169 SPBio_001052 C[C@@]12CCC3C(CCC4=CC(=O)CC[C@H]34)C2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E15 compound treatment 154325.0 -113000.0 -2.29 217423.0 -45900.0 -0.96 -2.2943 -0.9249 3177388 SPBio_001053 COc1ccc2[C@@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5c(OC)c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E16 compound treatment 265547.0 -1700.0 -0.03 246103.0 -17200.0 -0.36 -0.2774 -0.7716 1000139 SPBio_001054 CO[C@]1(NC(=O)C(C(=O)O)c2ccc(O)cc2)[C@H]3OCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E17 compound treatment 5797.0 -261000.0 -5.3 4306.0 -259000.0 -5.4 -7.5629 -1.0 876 SPBio_001055 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E18 compound treatment 286519.0 19300.0 0.39 287562.0 24300.0 0.51 0.634 0.9919 800 SPBio_001056 C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E19 compound treatment 275937.0 8690.0 0.18 272947.0 9660.0 0.2 0.267 0.9978 756 SPBio_001057 CCCCCCc1ccc(O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E20 compound treatment 269643.0 2400.0 0.05 256420.0 -6860.0 -0.14 -0.0667 -0.4418 1064 SPBio_001058 [O-][N+](=O)O[C@@H]1CO[C@@H]2[C@H](CO[C@H]12)O[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E21 compound treatment 270636.0 3390.0 0.07 285547.0 22300.0 0.46 0.3766 0.8031 1174 SPBio_001059 CN(C)CCCN1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E22 compound treatment 266175.0 -1070.0 -0.02 262004.0 -1280.0 -0.03 -0.0342 -0.9948 2935 SPBio_001060 CC(=O)NCc1c(I)c(NC(=O)C)c(I)c(C(=O)O)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E23 mock treatment 248851.0 -18400.0 -0.37 284759.0 21500.0 0.45 0.0527 0.0905 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 E24 mock treatment 266502.0 -743.0 -0.02 219397.0 -43900.0 -0.91 -0.6571 -0.7187 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F01 mock treatment 262862.0 -4380.0 -0.09 294279.0 31000.0 0.65 0.3938 0.6041 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F02 mock treatment 288920.0 21700.0 0.44 306553.0 43300.0 0.9 0.9481 0.9454 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F03 compound treatment 315986.0 48700.0 0.99 311367.0 48100.0 1.0 1.407 1.0 1114 SPBio_001061 NS(=O)(=O)c1cc2c(N=C(CSCc3ccccc3)NS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F04 compound treatment 286167.0 18900.0 0.38 292151.0 28900.0 0.6 0.6965 0.9764 957 SPBio_001062 NC(COC(=O)C=[N+]=[N-])C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F05 compound treatment 290092.0 22800.0 0.46 276969.0 13700.0 0.29 0.5291 0.9728 1001638 SPBio_001063 CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc2cccc(C)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F06 compound treatment 286582.0 19300.0 0.39 247046.0 -16200.0 -0.34 0.038 0.0734 3054072 SPBio_001064 OC(=O)CCCCCCCCCCCCC1CCC=C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F07 compound treatment 189903.0 -77300.0 -1.57 190122.0 -73200.0 -1.52 -2.1864 -0.9999 1337 SPBio_001065 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F08 compound treatment 267440.0 195.0 0.0 313755.0 50500.0 1.05 0.7463 0.7098 1020088 SPBio_001066 NNCc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F09 compound treatment 305972.0 38700.0 0.79 309646.0 46400.0 0.97 1.2381 0.9947 3173625 SPBio_001067 Nc1nc2n(cnc2c(=O)[nH]1)C3C[C@H](O)[C@@H](CO)O3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F10 compound treatment 330298.0 63100.0 1.28 307576.0 44300.0 0.92 1.5564 0.9872 2508 SPBio_001068 OC(=O)COc1cc(Cl)c(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F11 compound treatment 301377.0 34100.0 0.69 281446.0 18200.0 0.38 0.7569 0.9597 1031842 SPBio_001069 CC(=O)Oc1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F12 compound treatment 286631.0 19400.0 0.39 282639.0 19400.0 0.4 0.563 0.9999 2477 SPBio_001070 CCOP(=S)(OCC)SCSP(=S)(OCC)OCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F13 compound treatment 254970.0 -12300.0 -0.25 271182.0 7900.0 0.16 -0.0596 -0.1997 894 SPBio_001071 ClCCN(CCCl)P1(=O)NCCCO1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F14 compound treatment 260349.0 -6900.0 -0.14 293342.0 30100.0 0.63 0.344 0.5361 2476 SPBio_001072 CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F15 compound treatment 247522.0 -19700.0 -0.4 264768.0 1490.0 0.03 -0.2608 -0.6504 1125 SPBio_001073 CCOC(=O)NNc1nncc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F16 compound treatment 284644.0 17400.0 0.35 262726.0 -556.0 -0.01 0.2412 0.6835 2484 SPBio_001074 COP(=O)(OC)OC=C(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F17 compound treatment 268804.0 1560.0 0.03 233825.0 -29500.0 -0.61 -0.4116 -0.6698 964 SPBio_001075 CN(C)N=Nc1[nH]cnc1C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F18 compound treatment 293013.0 25800.0 0.52 275420.0 12100.0 0.25 0.5482 0.9445 2487 SPBio_001076 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F19 compound treatment 309617.0 42400.0 0.86 269329.0 6050.0 0.13 0.6965 0.8022 1480 SPBio_001077 Clc1ccc2oc(=O)[nH]c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F20 compound treatment 269596.0 2350.0 0.05 253474.0 -9810.0 -0.2 -0.1108 -0.528 2496 SPBio_001078 CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F21 compound treatment 258581.0 -8660.0 -0.18 271313.0 8030.0 0.17 -0.0059 -0.0243 2060468 SPBio_001079 CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F22 compound treatment 293048.0 25800.0 0.52 278064.0 14800.0 0.31 0.5876 0.9681 2523 SPBio_001080 CCOP(=S)(OCC)Oc1nc(Cl)c(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F23 mock treatment 283075.0 15800.0 0.32 267227.0 3940.0 0.08 0.285 0.8604 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 F24 mock treatment 243709.0 -23500.0 -0.48 248028.0 -15300.0 -0.32 -0.5621 -0.9805 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G01 mock treatment 280703.0 13500.0 0.27 264892.0 1610.0 0.03 0.2166 0.7881 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G02 mock treatment 271806.0 4560.0 0.09 266370.0 3090.0 0.06 0.1109 0.9843 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G03 compound treatment 319570.0 52300.0 1.06 309981.0 46700.0 0.97 1.438 0.9991 915 SPBio_001081 OC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G04 compound treatment 286510.0 19300.0 0.39 270204.0 6920.0 0.14 0.3781 0.9083 2060472 SPBio_001082 C[C@@]12CCC3C(C=CC4=CC(=O)CC[C@]34C)C2CC[C@@]1(O)CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G05 compound treatment 267459.0 214.0 0.0 287717.0 24400.0 0.51 0.363 0.7131 3173092 SPBio_001083 CN(C)CCOC(c1ccccc1)c2ccccc2.Cn1c(=O)n(C)c2nc(Cl)[nH]c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G06 compound treatment 288980.0 21700.0 0.44 287803.0 24500.0 0.51 0.6728 0.9973 815 SPBio_001084 CCN(CC)C(=O)c1cccc(C)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G07 compound treatment 309887.0 42600.0 0.86 326149.0 62900.0 1.31 1.5374 0.9797 3174481 SPBio_001085 CNC[C@@H](O)c1ccc(O)c(O)c1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G08 compound treatment 295642.0 28400.0 0.58 303551.0 40300.0 0.84 1.0003 0.9831 772 SPBio_001086 CCN1CCCC(C1)OC(=O)C(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G09 compound treatment 316602.0 49400.0 1.0 331580.0 68300.0 1.42 1.7136 0.9852 803 SPBio_001087 CCc1cc(ccn1)C(=S)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G10 compound treatment 300715.0 33500.0 0.68 283237.0 20000.0 0.42 0.7738 0.9723 904 SPBio_001088 NC(=O)CN1CCCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G11 compound treatment 288118.0 20900.0 0.42 291203.0 27900.0 0.58 0.7105 0.9878 1150 SPBio_001089 OC(=O)CCCCCCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G12 compound treatment 263518.0 -3730.0 -0.08 262037.0 -1250.0 -0.03 -0.0718 -0.8984 1111 SPBio_001090 CCC(C)C1NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(CCNC(=O)C(NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(NC1=O)C(C)CC)C(C)O)NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(NC(=O)C(CCNCS(=O)(=O)O)NC(=O)CCCCC(C)C)C(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G13 compound treatment 274679.0 7430.0 0.15 272695.0 9410.0 0.2 0.2452 0.9915 790 SPBio_001091 COc1ccc2[C@@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G14 compound treatment 180434.0 -86800.0 -1.76 213411.0 -49900.0 -1.04 -1.9791 -0.9684 1000054 SPBio_001092 CC(C)CC1NC(=O)C(CCCN)NC(=O)C(NC(=O)C2CCCN2C(=O)C(Cc3ccccc3)NC(=O)C(CC(C)C)NC(=O)C(CCCN)NC(=O)C(NC(=O)C4CCCN4C(=O)C(Cc5ccccc5)NC1=O)C(C)C)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G15 compound treatment 304899.0 37700.0 0.76 277167.0 13900.0 0.29 0.7443 0.9118 809 SPBio_001093 CNCCC=C1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G16 compound treatment 3393.0 -264000.0 -5.35 3540.0 -260000.0 -5.41 -7.6086 -1.0 464 SPBio_001094 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G17 compound treatment 274963.0 7720.0 0.16 292070.0 28800.0 0.6 0.5347 0.8627 1181 SPBio_001095 Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G18 compound treatment 295003.0 27800.0 0.56 274775.0 11500.0 0.24 0.5672 0.9275 1257 SPBio_001096 CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G19 compound treatment 286671.0 19400.0 0.39 319764.0 56500.0 1.18 1.1105 0.895 948 SPBio_001097 O=C1C(C(=O)c2ccccc12)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G20 compound treatment 306887.0 39600.0 0.8 260036.0 -3250.0 -0.07 0.5205 0.6453 3046211 SPBio_001098 CCC(C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C/C=C(\C)/[C@@H](OC4C[C@H](OC)C(O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2)C=C[C@@H]1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G21 compound treatment 272290.0 5050.0 0.1 263941.0 659.0 0.01 0.082 0.7949 3174102 SPBio_001099 OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G22 compound treatment 275228.0 7980.0 0.16 291110.0 27800.0 0.58 0.5244 0.8712 900 SPBio_001100 CN1C(=C(O)c2sccc2S1(=O)=O)C(=O)Nc3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G23 mock treatment 272775.0 5530.0 0.11 250041.0 -13200.0 -0.28 -0.1158 -0.3888 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 G24 mock treatment 272443.0 5200.0 0.11 269631.0 6350.0 0.13 0.168 0.9937 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H01 mock treatment 335042.0 67800.0 1.37 265619.0 2340.0 0.05 1.0063 0.7317 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H02 mock treatment 307204.0 40000.0 0.81 256652.0 -6630.0 -0.14 0.4751 0.5782 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H03 compound treatment 285203.0 18000.0 0.36 309806.0 46500.0 0.97 0.9428 0.9106 1104 SPBio_001101 C[C@H](CCC(=O)O)[C@H]1CCC2C3C(CC(=O)[C@]12C)[C@@]4(C)CCC(=O)CC4CC3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H04 compound treatment 305491.0 38200.0 0.78 302902.0 39600.0 0.83 1.1319 0.9995 2529 SPBio_001102 COP(=S)(OC)Oc1ccc(SC)c(C)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H05 compound treatment 306544.0 39300.0 0.8 290549.0 27300.0 0.57 0.965 0.9863 1430 SPBio_001103 CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H06 compound treatment 304448.0 37200.0 0.75 283465.0 20200.0 0.42 0.8306 0.9619 2531 SPBio_001104 CNC(=O)Oc1ccccc1OC(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H07 compound treatment 343295.0 76100.0 1.54 290517.0 27200.0 0.57 1.4914 0.9078 1409 SPBio_001105 CCCC(C)(COC(=O)N)COC(=O)NC(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H08 compound treatment 286586.0 19300.0 0.39 279379.0 16100.0 0.34 0.5144 0.997 2533 SPBio_001106 Clc1ccc(cc1)C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H09 compound treatment 305201.0 38000.0 0.77 324793.0 61500.0 1.28 1.4502 0.9702 1587 SPBio_001107 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)C[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H10 compound treatment 311383.0 44100.0 0.89 312612.0 49300.0 1.03 1.3594 0.9976 3177463 SPBio_001108 CC1=C(N2C(SC1)[C@H](NC(=O)[C@H](N)C3=CCC=CC3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H11 compound treatment 288545.0 21300.0 0.43 305227.0 41900.0 0.87 0.9232 0.9472 745 SPBio_001109 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H12 compound treatment 283021.0 15800.0 0.32 323844.0 60600.0 1.26 1.1183 0.8592 835 SPBio_001110 CC(=O)OC1CN2CCC1CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H13 compound treatment 269081.0 1840.0 0.04 272805.0 9520.0 0.2 0.1666 0.8254 436 SPBio_001111 CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H14 compound treatment 303503.0 36300.0 0.74 307481.0 44200.0 0.92 1.1709 0.9938 4164 SPBio_001112 CC(C(=O)O)c1ccc2c(c1)[nH]c3ccc(Cl)cc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H15 compound treatment 252198.0 -15000.0 -0.31 304489.0 41200.0 0.86 0.3913 0.4295 1575 SPBio_001113 CNC1=Nc2ccc(Cl)cc2C(=[N+]([O-])C1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H16 compound treatment 264210.0 -3030.0 -0.06 294504.0 31200.0 0.65 0.4164 0.6374 2060327 SPBio_001114 COc1cc2CCN(C)[C@H]3Oc4ccc(O)c(Oc5cc6[C@H](Cc7ccc(Oc(c1O)c32)cc7)N(C)CCc6cc5OC)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H17 compound treatment 63444.0 -204000.0 -4.13 74825.0 -188000.0 -3.93 -5.6977 -0.9997 3055248 SPBio_001115 C=CC(C1=CC(=O)C=CC1=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H18 compound treatment 286449.0 19200.0 0.39 301744.0 38500.0 0.8 0.8419 0.945 1522 SPBio_001116 CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H19 compound treatment 279989.0 12700.0 0.26 287351.0 24100.0 0.5 0.5372 0.9524 729 SPBio_001117 OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H20 compound treatment 259809.0 -7440.0 -0.15 281544.0 18300.0 0.38 0.1624 0.3969 3177316 SPBio_001118 C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H21 compound treatment 269509.0 2260.0 0.05 273799.0 10500.0 0.22 0.1874 0.8371 1113841 SPBio_001119 Oc1ccc2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H22 compound treatment 269178.0 1930.0 0.04 258237.0 -5050.0 -0.11 -0.0466 -0.4155 3063989 SPBio_001120 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)O/C=C/[C@@](C)(O)C(=O)[C@@H](C)C/C=C/[C@H]4[C@@H]5O[C@@]51C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H23 mock treatment 261952.0 -5290.0 -0.11 284518.0 21200.0 0.44 0.237 0.5205 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 H24 mock treatment 285315.0 18100.0 0.37 246117.0 -17200.0 -0.36 0.0062 0.0121 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I01 mock treatment 246142.0 -21100.0 -0.43 274724.0 11400.0 0.24 -0.134 -0.2735 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I02 mock treatment 305586.0 38300.0 0.78 262066.0 -1220.0 -0.03 0.5317 0.6837 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I03 compound treatment 278805.0 11600.0 0.23 252282.0 -11000.0 -0.23 0.0037 0.0112 969 SPBio_001121 CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I04 compound treatment 197806.0 -69400.0 -1.41 229289.0 -34000.0 -0.71 -1.4962 -0.9495 2558 SPBio_001122 c1ccc2c(c1)cc3ccc4cccc5ccc2c3c45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I05 compound treatment 298709.0 31500.0 0.64 311222.0 47900.0 1.0 1.1572 0.9765 3174228 SPBio_001123 CN[C@H]1C(O)C(O)C(CO)OC1OC2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](NC(=N)N)[C@@H](O)[C@@H]3NC(=N)N)OC(C)[C@]2(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I06 compound treatment 312999.0 45800.0 0.93 299297.0 36000.0 0.75 1.1864 0.9945 1009654 SPBio_001124 COc1ccc(cc1OC)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I07 compound treatment 245991.0 -21300.0 -0.43 252789.0 -10500.0 -0.22 -0.4593 -0.9505 1224 SPBio_001125 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2CC[C@@H]1OC(=O)CCC5CCCC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I08 compound treatment 256030.0 -11200.0 -0.23 283182.0 19900.0 0.41 0.1324 0.28 1012 SPBio_001126 Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I09 compound treatment 303131.0 35900.0 0.73 269624.0 6340.0 0.13 0.6079 0.8221 1139 SPBio_001127 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I10 compound treatment 275295.0 8050.0 0.16 309232.0 45900.0 0.96 0.7923 0.8159 3172974 SPBio_001128 C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)C4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I11 compound treatment 288424.0 21200.0 0.43 289953.0 26700.0 0.56 0.6965 0.9919 1188 SPBio_001129 NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I12 compound treatment 304616.0 37400.0 0.76 305827.0 42500.0 0.89 1.1624 0.9969 1206 SPBio_001130 CC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I13 compound treatment 274416.0 7170.0 0.15 282538.0 19300.0 0.4 0.3865 0.9057 1215 SPBio_001131 CC(NCCC(c1ccccc1)c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I14 compound treatment 280032.0 12800.0 0.26 265613.0 2330.0 0.05 0.2176 0.8252 3078331 SPBio_001132 OC(=O)c1cccc(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I15 compound treatment 283915.0 16700.0 0.34 258592.0 -4690.0 -0.1 0.1699 0.4829 1219 SPBio_001133 CC[C@@]12CCC3C(CCC4=CC(=O)CC[C@H]34)C2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I16 compound treatment 261635.0 -5610.0 -0.11 284031.0 20700.0 0.43 0.2252 0.5039 810 SPBio_001134 CCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I17 compound treatment 252088.0 -15200.0 -0.31 250765.0 -12500.0 -0.26 -0.4017 -0.9967 838 SPBio_001135 COc1ccc(C(=O)c2ccccc2)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I18 compound treatment 2029.0 -265000.0 -5.38 2803.0 -260000.0 -5.43 -7.639 -1.0 704 SPBio_001136 CN(C)c1ccc(cc1)C(=C2C=CC(=[N+](C)C)C=C2)c3ccc(cc3)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I19 compound treatment 284002.0 16800.0 0.34 278792.0 15500.0 0.32 0.4687 0.9997 3273 SPBio_001137 NNCCc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I20 compound treatment 254680.0 -12600.0 -0.25 274068.0 10800.0 0.22 -0.0212 -0.0625 1585 SPBio_001138 CC(C)c1ccc(C)c2ccc(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I21 compound treatment 272108.0 4860.0 0.1 270019.0 6740.0 0.14 0.169 0.9851 1131 SPBio_001139 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I22 compound treatment 284099.0 16900.0 0.34 275981.0 12700.0 0.26 0.4287 0.992 1000377 SPBio_001140 CC(C)c1nc(nc(c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)O)c2ccc(F)cc2)N(C)S(=O)(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I23 mock treatment 271812.0 4570.0 0.09 249841.0 -13400.0 -0.28 -0.1325 -0.4494 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 I24 mock treatment 302683.0 35400.0 0.72 251838.0 -11400.0 -0.24 0.3394 0.4484 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J01 mock treatment 252810.0 -14400.0 -0.29 276246.0 13000.0 0.27 -0.016 -0.0401 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J02 mock treatment 289784.0 22500.0 0.46 314954.0 51700.0 1.08 1.0843 0.9272 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J03 compound treatment 273547.0 6300.0 0.13 278273.0 15000.0 0.31 0.3112 0.9222 1000134 SPBio_001141 Nc1ccn(C2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J04 compound treatment 275905.0 8660.0 0.18 318978.0 55700.0 1.16 0.9446 0.8049 1000093 SPBio_001142 CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J05 compound treatment 308827.0 41600.0 0.84 307671.0 44400.0 0.92 1.25 0.9989 1113 SPBio_001143 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(=O)O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J06 compound treatment 319932.0 52700.0 1.07 305566.0 42300.0 0.88 1.3782 0.9954 2141064 SPBio_001144 COC1=C[C@@H]2[C@@H]3Cc4ccc(OC)c(O)c4[C@]2(CCN3C)CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J07 compound treatment 372288.0 105000.0 2.13 419769.0 156000.0 3.26 3.811 0.9787 3055370 SPBio_001145 COC(=O)c1c(C)c2Oc3c(Cl)c(OC(=O)C)c(Cl)c(C)c3C(=O)Oc2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J08 compound treatment 330600.0 63400.0 1.28 312822.0 49500.0 1.03 1.638 0.9941 3079387 SPBio_001146 CN(/C=N/c1ccc(C)cc1C)/C=N/c2ccc(C)cc2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J09 compound treatment 286175.0 18900.0 0.38 305407.0 42100.0 0.88 0.8919 0.9312 2069224 SPBio_001147 COc1ccc(cc1)c2c(O)c3cc4CCC(C)(C)Oc4c(CC=C(C)C)c3oc2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J10 compound treatment 311720.0 44500.0 0.9 299920.0 36600.0 0.76 1.1773 0.9966 3177525 SPBio_001148 NCCCC(N)C(=O)O.OC(=O)CCC(=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J11 compound treatment 285689.0 18400.0 0.37 268370.0 5090.0 0.11 0.3393 0.8731 2060359 SPBio_001149 COc1ccc(cc1)c2c(O)c3c(OC)c4C=CC(C)(C)Oc4cc3oc2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J12 compound treatment 104992.0 -162000.0 -3.29 122312.0 -141000.0 -2.94 -4.4026 -0.9984 885 SPBio_001150 Clc1ccc2Oc3ccccc3N=C(N4CCNCC4)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J13 compound treatment 3046.0 -264000.0 -5.36 2487.0 -261000.0 -5.43 -7.6291 -1.0 2060346 SPBio_001151 CC(=O)Oc1cc2c(CC=C3[C@@]2(C)CC[C@@]4(C)C5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O)c(C)c1OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J14 compound treatment 152840.0 -114000.0 -2.32 126444.0 -137000.0 -2.85 -3.6558 -0.9948 3046390 SPBio_001152 CCC(=O)O[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J15 compound treatment 288113.0 20900.0 0.42 288798.0 25500.0 0.53 0.675 0.9936 2060444 SPBio_001153 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c4c(=O)c(O)cccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J16 compound treatment 162698.0 -105000.0 -2.12 149001.0 -114000.0 -2.38 -3.1822 -0.9983 3198427 SPBio_001154 CCCCCCCCCc1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J17 compound treatment 311725.0 44500.0 0.9 279351.0 16100.0 0.33 0.8743 0.909 2060377 SPBio_001155 COc1c(ccc2OC(C)(C)CCc12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J18 compound treatment 307003.0 39800.0 0.81 242316.0 -21000.0 -0.44 0.2611 0.2848 1072288 SPBio_001156 CC(=C)C1CNC(C1CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J19 compound treatment 300944.0 33700.0 0.68 276526.0 13200.0 0.28 0.6782 0.9204 2060190 SPBio_001157 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@H](CC[C@]5(C)C4C(=O)[C@@H](OC(=O)C)[C@]23C)OC(=O)C)O[C@@]61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J20 compound treatment 269473.0 2230.0 0.05 303851.0 40600.0 0.85 0.6296 0.7438 3198428 SPBio_001158 CCOC(=O)[C@H](CCc1ccccc1)N[C@H](C)C(=O)N2[C@@H](CC3CCCCC32)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J21 compound treatment 275939.0 8690.0 0.18 271854.0 8570.0 0.18 0.2509 1.0 1312 SPBio_001159 C[As](=O)(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J22 compound treatment 267745.0 500.0 0.01 265447.0 2160.0 0.05 0.0391 0.845 1078453 SPBio_001160 Fc1ccc(cc1)C(=O)CCCN2CCN(CC2)c3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J23 mock treatment 297537.0 30300.0 0.61 265300.0 2020.0 0.04 0.464 0.7537 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 J24 mock treatment 266901.0 -344.0 -0.01 262198.0 -1080.0 -0.02 -0.0209 -0.8842 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K01 mock treatment 286636.0 19400.0 0.39 257916.0 -5370.0 -0.11 0.1989 0.4867 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K02 mock treatment 285596.0 18400.0 0.37 267536.0 4250.0 0.09 0.3257 0.8517 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K03 compound treatment 322847.0 55600.0 1.13 252367.0 -10900.0 -0.23 0.6363 0.5533 1024 SPBio_001161 c1ccc2c(c1)sc3ccccc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K04 compound treatment 299116.0 31900.0 0.65 310447.0 47200.0 0.98 1.1517 0.9793 2566 SPBio_001162 CCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K05 compound treatment 286650.0 19400.0 0.39 279417.0 16100.0 0.34 0.5159 0.9969 1518 SPBio_001163 OC(=O)c1cc(ccc1O)c2ccc(F)cc2F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K06 compound treatment 2880.0 -264000.0 -5.36 3580.0 -260000.0 -5.41 -7.6154 -1.0 3198423 SPBio_001164 CO/N=C/1\CN(CC1CN)c2nc3n(cc(C(=O)O)c(=O)c3cc2F)C4CC4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K07 compound treatment 291397.0 24200.0 0.49 342943.0 79700.0 1.66 1.5197 0.8783 1240 SPBio_001165 CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K08 compound treatment 331695.0 64500.0 1.31 318815.0 55500.0 1.16 1.742 0.9982 2060461 SPBio_001166 COc1ccc(C2COc3c(OC)c(O)ccc3C2)c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K09 compound treatment 286354.0 19100.0 0.39 289871.0 26600.0 0.55 0.6656 0.9847 1176 SPBio_001167 CC[C@@H](CO)NCCN[C@@H](CC)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K10 compound treatment 284576.0 17300.0 0.35 279852.0 16600.0 0.35 0.4925 1.0 2560 SPBio_001168 Cc1ccc2cc3c(ccc4ccccc43)c5CCc1c52 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K11 compound treatment 31851.0 -235000.0 -4.77 50626.0 -213000.0 -4.43 -6.5071 -0.9993 3043753 SPBio_001169 [O-][N+](=O)c1ccc(/C=N/N2CCOC2=O)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K12 compound treatment 272906.0 5660.0 0.11 256324.0 -6960.0 -0.14 -0.0214 -0.1155 2060305 SPBio_001170 CCCCC[C@H](CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K13 compound treatment 277631.0 10400.0 0.21 311723.0 48400.0 1.01 0.8625 0.8366 1000104 SPBio_001171 Cc1c(CCC(=O)O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5C=C)c(C)c4C=C)c(C)c3CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K14 compound treatment 301937.0 34700.0 0.7 294169.0 30900.0 0.64 0.9523 0.999 1661997 SPBio_001172 CC12CCC3C(CCc4cc(OC(=O)c5ccccc5)ccc34)C2CCC1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K15 compound treatment 204036.0 -63200.0 -1.28 219099.0 -44200.0 -0.92 -1.557 -0.9868 747 SPBio_001173 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCNCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K16 compound treatment 314997.0 47800.0 0.97 278494.0 15200.0 0.32 0.9086 0.892 796 SPBio_001174 Cc1ccc(C)c(OCCCC(C)(C)C(=O)O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K17 compound treatment 320782.0 53500.0 1.09 299815.0 36500.0 0.76 1.3056 0.9849 996 SPBio_001175 NCCc1cc(O)c(O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K18 compound treatment 286129.0 18900.0 0.38 291817.0 28500.0 0.59 0.6911 0.9773 3173859 SPBio_001176 CC(C)CC(=O)OC1C(O[C@@H]2C[C@H]([C@H]3CC[C@]4(CC5CC[C@H]4[C@]3(C)C2)[C@@H](O)C5=C)C(=O)O)OC(CO)C(OS(=O)(=O)O)C1OS(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K19 compound treatment 295849.0 28600.0 0.58 294584.0 31300.0 0.65 0.8712 0.9983 958 SPBio_001177 NC(=O)NC(=O)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K20 compound treatment 171634.0 -95600.0 -1.94 117321.0 -146000.0 -3.04 -3.5208 -0.9764 1324 SPBio_001178 CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K21 compound treatment 264009.0 -3240.0 -0.07 293694.0 30400.0 0.63 0.4016 0.6305 881 SPBio_001179 CC12C[C@H](O)C3C(CCC4=CC(=O)CCC34C)C2CC[C@]1(O)C(=O)COP(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K22 compound treatment 280674.0 13400.0 0.27 286888.0 23600.0 0.49 0.5402 0.9611 1000411 SPBio_001180 CCCCCNC(=N)N/N=C/c1c[nH]c2ccc(OC)cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K23 mock treatment 259588.0 -7660.0 -0.16 275160.0 11900.0 0.25 0.0652 0.2232 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 K24 mock treatment 262587.0 -4660.0 -0.09 273828.0 10500.0 0.22 0.0886 0.3704 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L01 mock treatment 283375.0 16100.0 0.33 269715.0 6430.0 0.13 0.326 0.9224 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L02 mock treatment 308691.0 41400.0 0.84 290354.0 27100.0 0.56 0.9929 0.9812 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L03 compound treatment 276806.0 9560.0 0.19 283252.0 20000.0 0.42 0.4312 0.9396 3198426 SPBio_001181 NCC(CC(=O)O)c1ccc(Cl)s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L04 compound treatment 348660.0 81400.0 1.65 330487.0 67200.0 1.4 2.1571 0.9966 3069053 SPBio_001182 CCOC(=O)n1ccn(C)c1=S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L05 compound treatment 309919.0 42700.0 0.87 301641.0 38400.0 0.8 1.1768 0.9992 3202 SPBio_001183 COc1ccccc1N2CCN(CCCNc3cc(=O)n(C)c(=O)n3C)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L06 compound treatment 346366.0 79100.0 1.6 300187.0 36900.0 0.77 1.6779 0.9433 2069303 SPBio_001184 COC(=O)CCC(=O)O[C@H]1CCC2(C)C(CCC3C4CC5OC6(CCC(C)CO6)[C@@H](C)C5C4(C)[C@H](O)C(=O)C32)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L07 compound treatment 295123.0 27900.0 0.57 351672.0 88400.0 1.84 1.7017 0.8835 3177465 SPBio_001185 CO[C@@H]1C[C@H](O[C@H]2CC[C@@]3(C)[C@H](CCC4C3CC[C@]5(C)[C@H]([C@H](C[C@]45O)OC(=O)C)C6=CC(=O)OC6)C2)OC(C)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L08 compound treatment 303891.0 36600.0 0.74 269068.0 5790.0 0.12 0.6106 0.8112 3054136 SPBio_001186 CC1(C)CC[C@]2(C)CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L09 compound treatment 344006.0 76800.0 1.56 309378.0 46100.0 0.96 1.7794 0.9731 1000807 SPBio_001187 CN1CCN(CC1)C(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L10 compound treatment 316089.0 48800.0 0.99 317154.0 53900.0 1.12 1.4938 0.9981 2060309 SPBio_001188 CC12CCC3C(CCC4(O)CC(O)CCC34/C=N/NC(=O)N)C2(O)CCC1C5=CC(=O)OC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L11 compound treatment 57089.0 -210000.0 -4.26 120726.0 -143000.0 -2.97 -5.1126 -0.9844 3174220 SPBio_001189 CO[C@@H]1C[C@@H](C[C@H]2CC[C@H](C)[C@@H](O2)[C@@H](C)C(=O)O)O[C@]3(O[C@@](C)(C[C@H]3C)[C@H]4CC[C@](C)(O4)C5O[C@H](C[C@@H]5C)C6O[C@@](O)(CO)[C@H](C)C[C@@H]6C)[C@@H]1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L12 compound treatment 288603.0 21400.0 0.43 273975.0 10700.0 0.22 0.4637 0.9523 3079388 SPBio_001190 COc1ccc2CC[C@H]3C[C@H](O)CC[C@]3(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L13 compound treatment 19008.0 -248000.0 -5.03 32223.0 -231000.0 -4.81 -6.9623 -0.9998 2038 SPBio_001191 CCN(CC)C(=S)SSC(=S)N(CC)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L14 compound treatment 326801.0 59600.0 1.21 329211.0 65900.0 1.37 1.8249 0.9979 967 SPBio_001192 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)/C=C/C=C(\C)/C=C/C2=C(C)CCCC2(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L15 compound treatment 304002.0 36800.0 0.75 291083.0 27800.0 0.58 0.9365 0.9922 1589 SPBio_001193 CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc2ccc(O)cc2)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L16 compound treatment 317770.0 50500.0 1.02 327270.0 64000.0 1.33 1.6669 0.9915 418 SPBio_001194 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L17 compound treatment 298075.0 30800.0 0.63 300108.0 36800.0 0.77 0.9844 0.9948 1214 SPBio_001195 CCOC(=O)Nc1c[n+](no1)N2CCOCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L18 compound treatment 292121.0 24900.0 0.5 326463.0 63200.0 1.32 1.2873 0.9133 1293 SPBio_001196 CC(=O)OCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L19 compound treatment 274533.0 7290.0 0.15 284873.0 21600.0 0.45 0.4225 0.8925 3480106 SPBio_001197 CC(C)(C(=O)O)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L20 compound treatment 299303.0 32100.0 0.65 285606.0 22300.0 0.47 0.7884 0.9865 746 SPBio_001198 C(N(Cc1ccccc1)c2ccccc2)C3=NCCN3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L21 compound treatment 277642.0 10400.0 0.21 277567.0 14300.0 0.3 0.3595 0.9857 3000787 SPBio_001199 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L22 compound treatment 277605.0 10400.0 0.21 249527.0 -13800.0 -0.29 -0.0541 -0.1523 3177462 SPBio_001200 CCCCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(O)C[C@@]21C)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L23 mock treatment 285734.0 18500.0 0.37 315481.0 52200.0 1.09 1.034 0.8989 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 L24 mock treatment 269556.0 2310.0 0.05 263170.0 -112.0 0.0 0.0315 0.671 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M01 mock treatment 249707.0 -17500.0 -0.36 270046.0 6760.0 0.14 -0.1518 -0.3968 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M02 mock treatment 283525.0 16300.0 0.33 271117.0 7830.0 0.16 0.3488 0.9473 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M03 compound treatment 289470.0 22200.0 0.45 301968.0 38700.0 0.81 0.8885 0.9623 1018 SPBio_001201 COc1ccc2C[C@H]3[C@@H]4CCCC[C@@]4(CCN3C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M04 compound treatment 333049.0 65800.0 1.33 306902.0 43600.0 0.91 1.5859 0.9825 1696 SPBio_001202 CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M05 compound treatment 321071.0 53800.0 1.09 279117.0 15800.0 0.33 1.0049 0.8815 1164 SPBio_001203 CCN(CC)C(=O)N1CCN(C)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M06 compound treatment 276737.0 9490.0 0.19 295074.0 31800.0 0.66 0.6044 0.8763 1012497 SPBio_001204 NC(Cc1c[nH]c2ccccc12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M07 compound treatment 151902.0 -115000.0 -2.34 252160.0 -11100.0 -0.23 -1.8173 -0.7734 1378 SPBio_001205 NCCc1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M08 compound treatment 82355.0 -185000.0 -3.75 139113.0 -124000.0 -2.59 -4.4796 -0.9836 3055 SPBio_001206 NC(=N)NCCN1CCCCCCC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M09 compound treatment 284213.0 17000.0 0.34 270184.0 6900.0 0.14 0.3449 0.9251 1462 SPBio_001207 CC1C(CCC(C)(C)N1C)OC(=O)C(O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M10 compound treatment 310895.0 43700.0 0.88 318892.0 55600.0 1.16 1.4449 0.9912 896 SPBio_001208 COc1ccccc1OCC(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M11 compound treatment 285567.0 18300.0 0.37 292706.0 29400.0 0.61 0.6961 0.9712 1000135 SPBio_001209 CC(C(=O)O)c1ccc(c(F)c1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M12 compound treatment 2908.0 -264000.0 -5.36 2888.0 -260000.0 -5.42 -7.6252 -1.0 1238 SPBio_001210 Oc1c(Cl)cc(Cl)c(Cl)c1Cc2c(O)c(Cl)cc(Cl)c2Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M13 compound treatment 191477.0 -75800.0 -1.54 279052.0 15800.0 0.33 -0.8538 -0.5436 2117626 SPBio_001211 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M14 compound treatment 282632.0 15400.0 0.31 317470.0 54200.0 1.13 1.0188 0.8699 1344 SPBio_001212 CCCC(=O)O[C@@]1(CCC2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M15 compound treatment 296909.0 29700.0 0.6 263737.0 455.0 0.01 0.4319 0.7182 1115 SPBio_001213 C[C@@]12CCC3C(CCC4=C3CCC(=O)C4)C2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M16 compound treatment 290792.0 23500.0 0.48 267845.0 4560.0 0.1 0.4048 0.8316 3055280 SPBio_001214 CCCCCCc1ccc(O)cc1O.Nc1c2ccccc2nc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M17 compound treatment 239456.0 -27800.0 -0.56 255641.0 -7640.0 -0.16 -0.5109 -0.8727 3173215 SPBio_001215 Cc1onc(c1C(=O)NC2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M18 compound treatment 252265.0 -15000.0 -0.3 270806.0 7520.0 0.16 -0.1039 -0.304 1001518 SPBio_001216 CCC[C@H](N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCCC[C@@H]21)C(=O)O)C(=O)OCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M19 compound treatment 290077.0 22800.0 0.46 281979.0 18700.0 0.39 0.6027 0.9963 952 SPBio_001217 CC(C)(S)[C@@H](N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M20 compound treatment 255128.0 -12100.0 -0.25 246054.0 -17200.0 -0.36 -0.4275 -0.9829 732 SPBio_001218 Oc1cc(cc([N+](=O)[O-])c1O)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M21 compound treatment 273129.0 5880.0 0.12 274546.0 11300.0 0.23 0.2503 0.9508 848 SPBio_001219 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M22 compound treatment 291559.0 24300.0 0.49 272855.0 9570.0 0.2 0.4896 0.9207 1402 SPBio_001220 CC[N+](C)(C)c1cccc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M23 mock treatment 250631.0 -16600.0 -0.34 288603.0 25300.0 0.53 0.1348 0.2154 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 M24 mock treatment 268054.0 809.0 0.02 273358.0 10100.0 0.21 0.16 0.76 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N01 mock treatment 303965.0 36700.0 0.74 258845.0 -4440.0 -0.09 0.461 0.6146 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N02 mock treatment 302944.0 35700.0 0.72 355406.0 92100.0 1.92 1.8688 0.9111 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N03 compound treatment 332381.0 65100.0 1.32 357448.0 94200.0 1.96 2.3209 0.9814 1331 SPBio_001221 CC(=O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N04 compound treatment 336350.0 69100.0 1.4 316840.0 53600.0 1.12 1.7796 0.9936 451 SPBio_001222 Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N05 compound treatment 319192.0 51900.0 1.05 279621.0 16300.0 0.34 0.9854 0.8903 1494 SPBio_001223 C1CN(CCN1)c2ccc3ccccc3n2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N06 compound treatment 319052.0 51800.0 1.05 318327.0 55000.0 1.15 1.5535 0.999 1454 SPBio_001224 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CCC6C5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N07 compound treatment 2389.0 -265000.0 -5.37 2823.0 -260000.0 -5.43 -7.6336 -1.0 1313 SPBio_001225 Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N08 compound treatment 2349.0 -265000.0 -5.37 2343.0 -261000.0 -5.44 -7.6412 -1.0 935 SPBio_001226 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N09 compound treatment 306954.0 39700.0 0.81 336683.0 73400.0 1.53 1.6505 0.9551 806 SPBio_001227 OC(=O)C1CCCNC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N10 compound treatment 324765.0 57500.0 1.17 335727.0 72400.0 1.51 1.8917 0.9919 1297 SPBio_001228 COc1cc(CC=C)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N11 compound treatment 236907.0 -30300.0 -0.62 195974.0 -67300.0 -1.4 -1.4264 -0.9316 1258 SPBio_001229 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCNCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N12 compound treatment 260493.0 -6750.0 -0.14 295765.0 32500.0 0.68 0.3817 0.5529 945 SPBio_001230 C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N13 compound treatment 284096.0 16900.0 0.34 295063.0 31800.0 0.66 0.7097 0.9526 2555 SPBio_001231 CCOC(=O)NC1=C(C2CC2)C(=O)C(=C(C3CC3)C1=O)NC(=O)OCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N14 compound treatment 290957.0 23700.0 0.48 298369.0 35100.0 0.73 0.8568 0.9793 694 SPBio_001232 C[C@H]1CC2C3CC[C@](O)(C(=O)C)[C@@]3(C)C[C@H](O)[C@]2(F)C4(C)C=CC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N15 compound treatment 261106.0 -6140.0 -0.12 294379.0 31100.0 0.65 0.3701 0.561 448 SPBio_001233 Clc1cccc(Cl)c1N=C2NCCN2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N16 compound treatment 2507.0 -265000.0 -5.37 3001.0 -260000.0 -5.42 -7.6293 -1.0 742 SPBio_001234 C[C@@H]1[C@H](O)CC[C@@]2(C)[C@H]1CC[C@@]3(C)C2[C@H](O)C[C@H]4/C(=C(/CCC=C(C)C)\C(=O)O)/[C@H](C[C@@]43C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N17 compound treatment 264514.0 -2730.0 -0.06 250532.0 -12800.0 -0.27 -0.227 -0.8365 1204 SPBio_001235 CN1C[C@@H](C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34)C(=O)N[C@]5(C)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C5=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N18 compound treatment 243299.0 -23900.0 -0.49 220104.0 -43200.0 -0.9 -0.9793 -0.9581 1261 SPBio_001236 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N19 compound treatment 198083.0 -69200.0 -1.4 228218.0 -35100.0 -0.73 -1.508 -0.9538 3173761 SPBio_001237 N[C@@H](C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)Cl)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N20 compound treatment 268414.0 1170.0 0.02 264368.0 1090.0 0.02 0.0328 0.9997 1136 SPBio_001238 C[C@@]12C[C@H](O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)COC(=O)CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N21 compound treatment 247766.0 -19500.0 -0.39 269694.0 6410.0 0.13 -0.1848 -0.4433 924 SPBio_001239 NC(=N)NC(=N)Nc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N22 compound treatment 223991.0 -43300.0 -0.88 249623.0 -13700.0 -0.28 -0.8213 -0.8908 859 SPBio_001240 CC(=O)O[C@@]1(CCC2C3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)C3CC[C@@]21C)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N23 mock treatment 210853.0 -56400.0 -1.14 282867.0 19600.0 0.41 -0.5199 -0.4283 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 N24 mock treatment 229807.0 -37400.0 -0.76 253482.0 -9800.0 -0.2 -0.681 -0.8665 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O01 mock treatment 244312.0 -22900.0 -0.46 255011.0 -8270.0 -0.17 -0.4506 -0.9088 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O02 mock treatment 282900.0 15700.0 0.32 268689.0 5410.0 0.11 0.3041 0.9029 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O03 compound treatment 293986.0 26700.0 0.54 288616.0 25300.0 0.53 0.7565 0.9999 3172851 SPBio_001241 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O04 compound treatment 286499.0 19300.0 0.39 244321.0 -19000.0 -0.4 -0.0033 -0.006 52159 SPBio_001242 COc1ccc2[nH]cc(CCN)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O05 compound treatment 297402.0 30200.0 0.61 265984.0 2700.0 0.06 0.4721 0.769 3059213 SPBio_001243 COc1ccc(C(=O)c2ccccc2O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O06 compound treatment 288260.0 21000.0 0.43 323749.0 60500.0 1.26 1.192 0.8964 1009556 SPBio_001244 Nc1c2ccccc2nc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O07 compound treatment 284561.0 17300.0 0.35 270458.0 7180.0 0.15 0.3539 0.9276 1112 SPBio_001245 CC(C)N(CCC(C(=O)N)(c1ccccc1)c2ccccn2)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O08 compound treatment 2202.0 -265000.0 -5.37 2887.0 -260000.0 -5.42 -7.6353 -1.0 2060287 SPBio_001246 Cc1c(O)c(O)cc2c1CC=C3[C@@]2(C)CC[C@@]4(C)C5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O09 compound treatment 299107.0 31900.0 0.65 262866.0 -416.0 -0.01 0.4506 0.6975 3058535 SPBio_001247 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O10 compound treatment 264452.0 -2790.0 -0.06 218137.0 -45100.0 -0.94 -0.7051 -0.7483 3044526 SPBio_001248 NC(=N)N/N=C\c1c(Cl)cccc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O11 compound treatment 293882.0 26600.0 0.54 282339.0 19100.0 0.4 0.6626 0.9886 3177453 SPBio_001249 CC(=O)OCC(=O)[C@]12OC(C)(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@@]31C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O12 compound treatment 199144.0 -68100.0 -1.38 249781.0 -13500.0 -0.28 -1.1751 -0.834 825 SPBio_001250 CC(Cc1ccc(O)c(O)c1)(NN)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O13 compound treatment 261266.0 -5980.0 -0.12 268828.0 5550.0 0.12 -0.004 -0.024 3045799 SPBio_001251 NC(=Nc1nc(CSCC/C(=N\S(=O)(=O)N)/N)cs1)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O14 compound treatment 2756.0 -264000.0 -5.36 2697.0 -261000.0 -5.43 -7.6302 -1.0 3173079 SPBio_001252 CC1(C)N[C@@H](C(=O)N1C2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O15 compound treatment 275089.0 7840.0 0.16 280169.0 16900.0 0.35 0.3612 0.9356 1509 SPBio_001253 Cn1c(COC(=O)N)ncc1[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O16 compound treatment 285704.0 18500.0 0.37 298723.0 35400.0 0.74 0.7867 0.9504 2060386 SPBio_001254 CCN1C[C@]2(C)CC[C@H](OC)[C@@]34C2[C@H](O)[C@]5(OCO[C@]65C[C@H](OC)[C@H]7C[C@]4(O)C6[C@H]7O)C13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O17 compound treatment 284359.0 17100.0 0.35 253037.0 -10200.0 -0.21 0.0944 0.2318 1443 SPBio_001255 CN(C)CCOC(c1ccccc1)c2ccccc2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O18 compound treatment 298047.0 30800.0 0.62 281034.0 17800.0 0.37 0.7031 0.9687 2857 SPBio_001256 O=C1CCc2cc(OCCCCc3nnnn3C4CCCCC4)ccc2N1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O19 compound treatment 260324.0 -6920.0 -0.14 261932.0 -1350.0 -0.03 -0.1191 -0.8323 719 SPBio_001257 CN(CC#C)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O20 compound treatment 225039.0 -42200.0 -0.86 269880.0 6600.0 0.14 -0.5078 -0.586 3198424 SPBio_001258 CN(C)CCCN1C(=C(C)Sc2ccccc12)/C=C(\C=C)/C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O21 compound treatment 276406.0 9160.0 0.19 273452.0 10200.0 0.21 0.2811 0.9978 931 SPBio_001259 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O22 compound treatment 253680.0 -13600.0 -0.28 294525.0 31200.0 0.65 0.2658 0.3762 3059817 SPBio_001260 CCCCC(=O)N(Cc1ccc(cc1)c2ccccc2c3nn[nH]n3)[C@@H](C(C)C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O23 mock treatment 246345.0 -20900.0 -0.42 271645.0 8360.0 0.17 -0.1764 -0.3851 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 O24 mock treatment 268860.0 1620.0 0.03 279642.0 16400.0 0.34 0.2641 0.7715 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P01 mock treatment 287897.0 20700.0 0.42 245730.0 -17600.0 -0.37 0.0375 0.0674 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P02 mock treatment 272342.0 5100.0 0.1 291792.0 28500.0 0.59 0.493 0.8178 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P03 compound treatment 286075.0 18800.0 0.38 262007.0 -1280.0 -0.03 0.2511 0.6563 1213 SPBio_001261 CNCCc1ccccn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P04 compound treatment 290554.0 23300.0 0.47 238633.0 -24600.0 -0.51 -0.029 -0.0415 3198429 SPBio_001262 CC(=O)O[C@@]1(CCC2C3C=C(C)C4=CC(=O)CCC4(C)C3CCC21C)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P05 compound treatment 295788.0 28500.0 0.58 286630.0 23300.0 0.49 0.7531 0.9963 749 SPBio_001263 NC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P06 compound treatment 278927.0 11700.0 0.24 283487.0 20200.0 0.42 0.4651 0.963 1062 SPBio_001264 COc1ccccc1OCC(O)COC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P07 compound treatment 284014.0 16800.0 0.34 271280.0 8000.0 0.17 0.3582 0.9461 1119 SPBio_001265 CSCCC(NC=O)C(=O)NC(Cc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P08 compound treatment 243334.0 -23900.0 -0.48 245801.0 -17500.0 -0.36 -0.6003 -0.9901 842 SPBio_001266 Cn1cc[nH]c1=S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P09 compound treatment 73194.0 -194000.0 -3.93 52542.0 -211000.0 -4.39 -5.8862 -0.9985 449 SPBio_001267 CC1=CC(=O)c2ccccc2C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P10 compound treatment 260262.0 -6980.0 -0.14 247918.0 -15400.0 -0.32 -0.3264 -0.9327 1234 SPBio_001268 C[C@H]1CC2C3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P11 compound treatment 295224.0 28000.0 0.57 273648.0 10400.0 0.22 0.5538 0.9124 1464728 SPBio_001269 Cn1c(=O)[nH]c2nc[nH]c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P12 compound treatment 233726.0 -33500.0 -0.68 257188.0 -6090.0 -0.13 -0.5703 -0.8249 3045140 SPBio_001270 CC(C)[N+]1(C)C2CC[C@@H]1C[C@H](C2)OC(=O)C(CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P13 compound treatment 259686.0 -7560.0 -0.15 268767.0 5480.0 0.11 -0.0276 -0.1442 925 SPBio_001271 C[C@@H]([C@H](O)c1ccccc1)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P14 compound treatment 263559.0 -3690.0 -0.07 257673.0 -5610.0 -0.12 -0.1355 -0.9767 1321 SPBio_001272 Cc1cc(=O)[nH]c(=S)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P15 compound treatment 219765.0 -47500.0 -0.96 257999.0 -5280.0 -0.11 -0.7585 -0.7829 1492782 SPBio_001273 OCNC(=O)c1cccnc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P16 compound treatment 248230.0 -19000.0 -0.39 285457.0 22200.0 0.46 0.0541 0.0899 884 SPBio_001274 CN(C)CCC(c1ccccc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P17 compound treatment 272971.0 5730.0 0.12 250767.0 -12500.0 -0.26 -0.1023 -0.3584 771 SPBio_001275 CN1CCC(=C2c3ccsc3C(=O)Cc4ccccc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P18 compound treatment 251107.0 -16100.0 -0.33 299476.0 36200.0 0.75 0.3018 0.3672 822 SPBio_001276 CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P19 compound treatment 218039.0 -49200.0 -1.0 183475.0 -79800.0 -1.66 -1.881 -0.9701 1130 SPBio_001277 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P20 compound treatment 38955.0 -228000.0 -4.63 55024.0 -208000.0 -4.34 -6.3404 -0.9995 1511 SPBio_001278 Oc1ccc(cc1)C2(OC(=O)c3ccccc32)c4ccc(O)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P21 compound treatment 209624.0 -57600.0 -1.17 245647.0 -17600.0 -0.37 -1.0858 -0.8867 752 SPBio_001279 CC1CCc2cc(F)cc3c(=O)c(cn1c23)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P22 compound treatment 235583.0 -31700.0 -0.64 255279.0 -8000.0 -0.17 -0.5718 -0.8622 1208 SPBio_001280 CNC[C@H](O)c1cccc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P23 mock treatment 236223.0 -31000.0 -0.63 247626.0 -15700.0 -0.33 -0.6753 -0.9533 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2161 P24 mock treatment 244558.0 -22700.0 -0.46 251243.0 -12000.0 -0.25 -0.5026 -0.9593 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A01 mock treatment 227536.0 -36500.0 -0.74 233993.0 -18100.0 -0.38 -0.7894 -0.9507 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A02 mock treatment 219896.0 -44200.0 -0.9 215025.0 -37000.0 -0.77 -1.1784 -0.9973 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A03 compound treatment 256960.0 -7090.0 -0.14 243100.0 -8950.0 -0.19 -0.2335 -0.9917 1126 SPBio_001281 O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A04 compound treatment 231775.0 -32300.0 -0.65 246659.0 -5390.0 -0.11 -0.5421 -0.8165 1065 SPBio_001282 CN1C(CC(O)c2ccccc2)CCCC1CC(=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A05 compound treatment 249322.0 -14700.0 -0.3 226843.0 -25200.0 -0.53 -0.5824 -0.9642 968 SPBio_001283 CCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A06 compound treatment 162024.0 -102000.0 -2.07 175835.0 -76200.0 -1.59 -2.5853 -0.9915 802 SPBio_001284 Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A07 compound treatment 228483.0 -35600.0 -0.72 242456.0 -9590.0 -0.2 -0.6512 -0.8703 976 SPBio_001285 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A08 compound treatment 241685.0 -22400.0 -0.45 246017.0 -6030.0 -0.13 -0.4095 -0.8703 1284 SPBio_001286 OC(=O)CN(CC(=O)O)Cc1cc2c(c3ccccc3C(=O)O)c4cc(CN(CC(=O)O)CC(=O)O)c(=O)cc4oc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A09 compound treatment 256315.0 -7730.0 -0.16 255019.0 2970.0 0.06 -0.0671 -0.3983 992 SPBio_001287 CC[C@H]1[C@@H](Cc2cncn2C)COC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A10 compound treatment 261559.0 -2490.0 -0.05 238988.0 -13100.0 -0.27 -0.2281 -0.8242 686 SPBio_001288 C(Nc1ncnc2[nH]cnc12)c3ccco3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A11 compound treatment 281273.0 17200.0 0.35 248895.0 -3150.0 -0.07 0.2004 0.5641 1428 SPBio_001289 CC(C)NCC(O)COc1cccc2[nH]ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A12 compound treatment 275229.0 11200.0 0.23 242858.0 -9190.0 -0.19 0.0249 0.0838 3058615 SPBio_001290 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A13 compound treatment 49276.0 -215000.0 -4.35 183230.0 -68800.0 -1.43 -4.0926 -0.8928 3173725 SPBio_001291 CCN1CCN(C(=O)NC(C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4)C(=O)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A14 compound treatment 232454.0 -31600.0 -0.64 232715.0 -19300.0 -0.4 -0.7377 -0.975 2069337 SPBio_001292 COC(=O)C(C)c1ccc(cc1)C(=O)c2cccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A15 compound treatment 218267.0 -45800.0 -0.93 224113.0 -27900.0 -0.58 -1.0678 -0.9747 347 SPBio_001293 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A16 compound treatment 42166.0 -222000.0 -4.5 194382.0 -57700.0 -1.2 -4.0302 -0.8656 1606 SPBio_001294 NS(=O)(=O)c1cc2c(NC(CSCC=C)NS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A17 compound treatment 231227.0 -32800.0 -0.67 221366.0 -30700.0 -0.64 -0.9225 -0.9998 1000106 SPBio_001295 O=C(C1CCCCC1)N2CC3N(CCc4ccccc34)C(=O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A18 compound treatment 212275.0 -51800.0 -1.05 208728.0 -43300.0 -0.9 -1.3804 -0.9972 2060333 SPBio_001296 COc1ccc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A19 compound treatment 228510.0 -35500.0 -0.72 225423.0 -26600.0 -0.55 -0.9017 -0.9917 349 SPBio_001297 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A20 compound treatment 275453.0 11400.0 0.23 255249.0 3200.0 0.07 0.2106 0.8753 3054675 SPBio_001298 CC(C)CCCC(C)C1CCC2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCCC12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A21 compound treatment 206725.0 -57300.0 -1.16 216691.0 -35400.0 -0.74 -1.3426 -0.9758 1289 SPBio_001299 C[C@@]12C[C@H](O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A22 compound treatment 209335.0 -54700.0 -1.11 210282.0 -41800.0 -0.87 -1.3996 -0.9928 2060331 SPBio_001300 CC1=CCC(=C)[C@H]2CC(C)(C)[C@@H]2CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A23 mock treatment 219602.0 -44400.0 -0.9 223171.0 -28900.0 -0.6 -1.0626 -0.9807 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 A24 mock treatment 295178.0 31100.0 0.63 199828.0 -52200.0 -1.09 -0.3231 -0.2569 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B01 mock treatment 235425.0 -28600.0 -0.58 222416.0 -29600.0 -0.62 -0.8469 -0.9995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B02 mock treatment 255137.0 -8910.0 -0.18 271583.0 19500.0 0.41 0.16 0.3593 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B03 compound treatment 2851.0 -261000.0 -5.3 2322.0 -250000.0 -5.2 -7.4231 -1.0 1531 SPBio_001301 O=c1n([se]c2ccccc12)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B04 compound treatment 267930.0 3880.0 0.08 267626.0 15600.0 0.32 0.2851 0.8538 1339 SPBio_001302 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(=O)(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B05 compound treatment 67480.0 -197000.0 -3.99 133766.0 -118000.0 -2.46 -4.5603 -0.9733 1168 SPBio_001303 CC12CCC3C(CCc4cc(OCc5ccccc5)ccc34)C2C[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B06 compound treatment 3548.0 -261000.0 -5.28 3333.0 -249000.0 -5.18 -7.3982 -1.0 691 SPBio_001304 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)c4ccccc4)C(=O)N2C1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B07 compound treatment 259132.0 -4920.0 -0.1 237509.0 -14500.0 -0.3 -0.2847 -0.8927 2060367 SPBio_001305 CS(=O)(=O)CCCCN=C=S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B08 compound treatment 13447.0 -251000.0 -5.08 15527.0 -237000.0 -4.93 -7.0767 -0.9999 3173981 SPBio_001306 CCOC(=O)OC(C)OC(=O)C1N2C(SC1(C)C)C(NC(=O)[C@H](N)c3ccccc3)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B09 compound treatment 267098.0 3050.0 0.06 266712.0 14700.0 0.31 0.2597 0.8333 902 SPBio_001307 OC(=O)c1cc2cc(Cc3cccnc3)ccc2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B10 compound treatment 272214.0 8160.0 0.17 253001.0 951.0 0.02 0.1311 0.7862 917 SPBio_001308 NS(=O)(=O)c1cc2c(NC(Cc3ccccc3)NS2(=O)=O)cc1C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B11 compound treatment 210673.0 -53400.0 -1.08 205918.0 -46100.0 -0.96 -1.4447 -0.9982 1045 SPBio_001309 C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B12 compound treatment 269656.0 5610.0 0.11 282862.0 30800.0 0.64 0.5343 0.8196 841 SPBio_001310 C/C(=C(/CCOP(=O)(O)O)\SC(=O)c1ccccc1)/N(Cc2cnc(C)nc2N)C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B13 compound treatment 287586.0 23500.0 0.48 259796.0 7750.0 0.16 0.4515 0.8964 1258696 SPBio_001311 Cc1c(Cl)cccc1Nc2ccccc2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B14 compound treatment 269854.0 5800.0 0.12 239555.0 -12500.0 -0.26 -0.1009 -0.353 1082 SPBio_001312 CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B15 compound treatment 274564.0 10500.0 0.21 241379.0 -10700.0 -0.22 -0.0065 -0.021 1196 SPBio_001313 CCCOc1ccccc1c2nc3[nH]nnc3c(=O)[nH]2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B16 compound treatment 272194.0 8140.0 0.17 259976.0 7930.0 0.17 0.2335 1.0 955 SPBio_001314 CCN(CC)CCNC(=O)c1cc(Br)c(N)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B17 compound treatment 264326.0 276.0 0.01 261499.0 9450.0 0.2 0.1432 0.7269 1076 SPBio_001315 Cc1cccc(C)c1NC2=NCCCS2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B18 compound treatment 289421.0 25400.0 0.51 235773.0 -16300.0 -0.34 0.1239 0.2012 1000338 SPBio_001316 NC[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B19 compound treatment 302169.0 38100.0 0.77 251197.0 -853.0 -0.02 0.5339 0.6907 196 SPBio_001317 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B20 compound treatment 235570.0 -28500.0 -0.58 227798.0 -24300.0 -0.51 -0.7655 -0.9978 2359 SPBio_001318 CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@@H]32)n1c5ccccc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B21 compound treatment 262968.0 -1080.0 -0.02 266190.0 14100.0 0.29 0.1928 0.6527 1000121 SPBio_001319 C/C(=C\CO)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B22 compound treatment 255168.0 -8880.0 -0.18 262197.0 10100.0 0.21 0.0222 0.0798 755 SPBio_001320 CC(CN(C)C)CN1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B23 mock treatment 262315.0 -1730.0 -0.04 231636.0 -20400.0 -0.43 -0.3256 -0.763 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 B24 mock treatment 260339.0 -3710.0 -0.08 225488.0 -26600.0 -0.55 -0.4445 -0.7959 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C01 mock treatment 246957.0 -17100.0 -0.35 260445.0 8400.0 0.17 -0.1213 -0.3126 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C02 mock treatment 277336.0 13300.0 0.27 272410.0 20400.0 0.42 0.4904 0.976 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C03 compound treatment 76379.0 -188000.0 -3.8 69933.0 -182000.0 -3.79 -5.3731 -1.0 1455 SPBio_001321 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C04 compound treatment 92537.0 -172000.0 -3.48 70576.0 -181000.0 -3.78 -5.132 -0.9991 1031375 SPBio_001322 NC(CCCNC(=O)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C05 compound treatment 275536.0 11500.0 0.23 295362.0 43300.0 0.9 0.8027 0.8614 1273 SPBio_001323 C[C@@]12CC(=O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C06 compound treatment 199241.0 -64800.0 -1.31 206675.0 -45400.0 -0.95 -1.5975 -0.987 3054270 SPBio_001324 COC(=O)[C@@H]1C(O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C07 compound treatment 299303.0 35300.0 0.71 256510.0 4460.0 0.09 0.5711 0.7924 962 SPBio_001325 CCC1(C(=O)NCNC1=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C08 compound treatment 260419.0 -3630.0 -0.07 272684.0 20600.0 0.43 0.2519 0.5776 2060265 SPBio_001326 COC(=O)CCC(C)[C@H]1CCC2C3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C09 compound treatment 274839.0 10800.0 0.22 268298.0 16200.0 0.34 0.394 0.9777 722 SPBio_001327 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C10 compound treatment 18297.0 -246000.0 -4.98 24125.0 -228000.0 -4.75 -6.8805 -0.9997 2060267 SPBio_001328 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C11 compound treatment 272207.0 8160.0 0.17 253833.0 1780.0 0.04 0.1432 0.8449 2431 SPBio_001329 CCN(CC)CCNC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C12 compound treatment 242713.0 -21300.0 -0.43 274696.0 22600.0 0.47 0.0277 0.0433 3177457 SPBio_001330 CC(CCC(=O)O)[C@H]1CCC2C3C(CC(=O)[C@]12C)[C@@]4(C)CCC(=O)C[C@H]4CC3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C13 compound treatment 286937.0 22900.0 0.46 238216.0 -13800.0 -0.29 0.1243 0.2276 779 SPBio_001331 CCN(CC)CCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C14 compound treatment 268327.0 4280.0 0.09 245418.0 -6630.0 -0.14 -0.0364 -0.223 3174369 SPBio_001332 C[C@H]1OC(C[C@H](O)C1O)O[C@@H]2[C@@H](C)OC(C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6C5CC[C@]7(C)[C@H]([C@@H](O)C[C@]67O)C8=CC(=O)OC8)C4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C15 compound treatment 192393.0 -71700.0 -1.45 202997.0 -49100.0 -1.02 -1.7498 -0.9852 1041 SPBio_001333 CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C16 compound treatment 250628.0 -13400.0 -0.27 266780.0 14700.0 0.31 0.0246 0.06 2880 SPBio_001334 N[C@@H](CCC(=O)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C17 compound treatment 271765.0 7720.0 0.16 244373.0 -7680.0 -0.16 -0.0025 -0.0111 1057 SPBio_001335 OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C18 compound treatment 224952.0 -39100.0 -0.79 243271.0 -8780.0 -0.18 -0.6898 -0.848 2060276 SPBio_001336 C[C@@H]1C(=O)OC2[C@H](O)C34[C@@H]5OC(=O)[C@@]4(O[C@@H]6OC(=O)[C@H](O)[C@@]63[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C19 compound treatment 253631.0 -10400.0 -0.21 256493.0 4440.0 0.09 -0.0839 -0.3638 1000117 SPBio_001337 CC(=O)[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C20 compound treatment 264589.0 539.0 0.01 249329.0 -2720.0 -0.06 -0.0323 -0.5603 1275107 SPBio_001338 C1Cc2c(CN1)[nH]c3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C21 compound treatment 275302.0 11300.0 0.23 251021.0 -1030.0 -0.02 0.1462 0.6379 1397 SPBio_001339 CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C22 compound treatment 236143.0 -27900.0 -0.57 255297.0 3250.0 0.07 -0.3522 -0.6181 2060253 SPBio_001340 NC(CC(=O)c1ccccc1N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C23 mock treatment 267532.0 3480.0 0.07 229968.0 -22100.0 -0.46 -0.2754 -0.5917 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 C24 mock treatment 221714.0 -42300.0 -0.86 216779.0 -35300.0 -0.73 -1.1265 -0.997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D01 mock treatment 260514.0 -3540.0 -0.07 261133.0 9080.0 0.19 0.0831 0.4108 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D02 mock treatment 233862.0 -30200.0 -0.61 281669.0 29600.0 0.62 0.0036 0.0041 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D03 compound treatment 196598.0 -67500.0 -1.37 204552.0 -47500.0 -0.99 -1.6666 -0.9874 1205 SPBio_001341 CC(=CCC1=C(O)C(=O)c2ccccc2C1=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D04 compound treatment 250414.0 -13600.0 -0.28 265140.0 13100.0 0.27 -0.0026 -0.0068 1385 SPBio_001342 C(/C=C/N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D05 compound treatment 57405.0 -207000.0 -4.19 228443.0 -23600.0 -0.49 -3.31 -0.7847 1277 SPBio_001343 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](OC(=O)C)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](C)O3)[C@@H](C)O2)O[C@H]5CC[C@@]6(C)C(CCC7C6C[C@@H](O)[C@]8(C)[C@H](CC[C@]78O)C9=CC(=O)OC9)C5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D06 compound treatment 244480.0 -19600.0 -0.4 280642.0 28600.0 0.6 0.1407 0.1965 1442 SPBio_001344 CC(=O)NC1SCCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D07 compound treatment 299626.0 35600.0 0.72 284832.0 32800.0 0.68 0.9929 0.9996 3172730 SPBio_001345 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccco4)ncnc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D08 compound treatment 2980.0 -261000.0 -5.29 2414.0 -250000.0 -5.2 -7.4199 -1.0 1054 SPBio_001346 CC(C)(C)CC(C)(C)c1ccc(O)c(Cc2ccc(Cl)cc2Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D09 compound treatment 278897.0 14800.0 0.3 249372.0 -2680.0 -0.06 0.1734 0.5664 1009973 SPBio_001347 OC(C(O)C(O)C(=O)O)C(O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D10 compound treatment 247390.0 -16700.0 -0.34 261385.0 9340.0 0.19 -0.1013 -0.2599 716 SPBio_001348 CN(C)CCC=C1c2ccccc2C=Cc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D11 compound treatment 249032.0 -15000.0 -0.3 272006.0 20000.0 0.42 0.0787 0.1527 1036 SPBio_001349 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D12 compound treatment 207941.0 -56100.0 -1.14 222546.0 -29500.0 -0.61 -1.2389 -0.9582 1063 SPBio_001350 CC(CNCCc1ccc(O)c(O)c1)Cc2cccc(O)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D13 compound treatment 282594.0 18500.0 0.38 238737.0 -13300.0 -0.28 0.0697 0.1493 1608 SPBio_001351 NCCCC[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N2CCC[C@H]2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D14 compound treatment 250142.0 -13900.0 -0.28 262551.0 10500.0 0.22 -0.0447 -0.1252 1507 SPBio_001352 CC(N)CCCC(C)(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D15 compound treatment 243075.0 -21000.0 -0.43 264393.0 12300.0 0.26 -0.1188 -0.2392 769 SPBio_001353 CCCCOc1ccc(CC(=O)NO)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D16 compound treatment 239912.0 -24100.0 -0.49 232931.0 -19100.0 -0.4 -0.6277 -0.9948 766 SPBio_001354 CC12CCC3C(CCC4=CC(=O)CCC34C)C2CCC1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D17 compound treatment 258717.0 -5330.0 -0.11 242342.0 -9710.0 -0.2 -0.2194 -0.957 717 SPBio_001355 OC(=O)c1ccccc1OP(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D18 compound treatment 248581.0 -15500.0 -0.31 264575.0 12500.0 0.26 -0.0372 -0.0913 1348 SPBio_001356 Clc1ccc(OCC(=O)N2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D19 compound treatment 263645.0 -405.0 -0.01 227955.0 -24100.0 -0.5 -0.3607 -0.7186 1117 SPBio_001357 Nc1nc(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)cnc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D20 compound treatment 258010.0 -6040.0 -0.12 239257.0 -12800.0 -0.27 -0.275 -0.9377 1158 SPBio_001358 C(C(C1CCCCC1)C2CCCCC2)C3CCCCN3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D21 compound treatment 243300.0 -20700.0 -0.42 202802.0 -49200.0 -1.03 -1.0229 -0.9225 3079211 SPBio_001359 COC(=O)[C@]1(C)CCC[C@@]2(C)C1CC(=O)c3cc(ccc32)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D22 compound treatment 251667.0 -12400.0 -0.25 251394.0 -656.0 -0.01 -0.1872 -0.7445 3046112 SPBio_001360 CC1(C)O[C@@H]2CC3C4CCC5=CC(=O)CCC5(C)C4(F)C(O)CC3(C)[C@@]2(O1)C(=O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D23 mock treatment 254784.0 -9270.0 -0.19 247076.0 -4970.0 -0.1 -0.2061 -0.9607 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 D24 mock treatment 225435.0 -38600.0 -0.78 238339.0 -13700.0 -0.29 -0.7555 -0.9066 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E01 mock treatment 269412.0 5360.0 0.11 243915.0 -8130.0 -0.17 -0.043 -0.2134 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E02 mock treatment 259340.0 -4710.0 -0.1 239776.0 -12300.0 -0.26 -0.2483 -0.9098 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E03 compound treatment 250265.0 -13800.0 -0.28 261849.0 9800.0 0.2 -0.0532 -0.1539 351 SPBio_001361 CC(C)NCC(O)COc1cccc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E04 compound treatment 285942.0 21900.0 0.44 293962.0 41900.0 0.87 0.9312 0.9508 2069275 SPBio_001362 CC1(C)[C@H](CC[C@@]2(C)C1CC[C@@]3(C)C4CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC(=O)C32)C(=O)O)O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C(=O)O)[C@H](O)[C@H]6O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E05 compound treatment 252978.0 -11100.0 -0.22 258596.0 6550.0 0.14 -0.0623 -0.2371 912 SPBio_001363 CCCc1cc(=O)[nH]c(=S)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E06 compound treatment 134836.0 -129000.0 -2.62 156274.0 -95800.0 -2.0 -3.2632 -0.991 43 SPBio_001364 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E07 compound treatment 276620.0 12600.0 0.25 261202.0 9150.0 0.19 0.315 0.9898 1000118 SPBio_001365 CN[C@@H](C)[C@@H](O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E08 compound treatment 276403.0 12400.0 0.25 289643.0 37600.0 0.78 0.7309 0.8889 936 SPBio_001366 OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E09 compound treatment 271030.0 6980.0 0.14 245213.0 -6840.0 -0.14 -6.0E-4 -0.0032 3173593 SPBio_001367 CN1CCCN=C1/C=C/c2cccs2.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E10 compound treatment 240107.0 -23900.0 -0.49 222368.0 -29700.0 -0.62 -0.7805 -0.9928 837 SPBio_001368 CCOc1ccc2NC(C)(C)C=C(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E11 compound treatment 215518.0 -48500.0 -0.98 252023.0 -26.5 0.0 -0.6961 -0.7075 889 SPBio_001369 NC(=O)c1cnccn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E12 compound treatment 265849.0 1800.0 0.04 296031.0 44000.0 0.92 0.6737 0.7347 852 SPBio_001370 CCOc1ccc(Cc2nccc3cc(OCC)c(OCC)cc23)cc1OCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E13 compound treatment 285539.0 21500.0 0.44 276818.0 24800.0 0.52 0.6729 0.9965 830 SPBio_001371 COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E14 compound treatment 240627.0 -23400.0 -0.47 251007.0 -1040.0 -0.02 -0.3511 -0.7387 764 SPBio_001372 Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)n3c(=O)[nH]c4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E15 compound treatment 153611.0 -110000.0 -2.24 203051.0 -49000.0 -1.02 -2.305 -0.9367 3174105 SPBio_001373 CN(C)c1ccc2[n+](C)c(/C=C/c3cc(C)n(c3C)c4ccccc4)ccc2c1.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E16 compound treatment 271468.0 7420.0 0.15 275709.0 23700.0 0.49 0.4549 0.8827 805 SPBio_001374 CCc1cccc2c3CCOC(CC)(CC(=O)O)c3[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E17 compound treatment 270153.0 6100.0 0.12 300293.0 48200.0 1.01 0.7982 0.7882 792 SPBio_001375 COc1ccc2nccc([C@@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E18 compound treatment 300886.0 36800.0 0.75 289720.0 37700.0 0.78 1.083 0.9997 1033 SPBio_001376 CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E19 compound treatment 263695.0 -355.0 -0.01 275447.0 23400.0 0.49 0.3396 0.6966 836 SPBio_001377 CNC(C)C(O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E20 compound treatment 243943.0 -20100.0 -0.41 243660.0 -8390.0 -0.17 -0.4118 -0.9285 699 SPBio_001378 OC(=O)CCC(=O)c1ccc(cc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E21 compound treatment 293151.0 29100.0 0.59 245242.0 -6810.0 -0.14 0.3169 0.5223 711 SPBio_001379 Oc1cccc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E22 compound treatment 220358.0 -43700.0 -0.89 255691.0 3640.0 0.08 -0.5727 -0.6442 1172 SPBio_001380 CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E23 mock treatment 269546.0 5500.0 0.11 288364.0 36300.0 0.76 0.6137 0.8026 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 E24 mock treatment 255484.0 -8570.0 -0.17 251446.0 -604.0 -0.01 -0.1317 -0.7563 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F01 mock treatment 292170.0 28100.0 0.57 267510.0 15500.0 0.32 0.6309 0.9635 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F02 mock treatment 266176.0 2130.0 0.04 269672.0 17600.0 0.37 0.2901 0.7847 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F03 compound treatment 299223.0 35200.0 0.71 311764.0 59700.0 1.24 1.3839 0.9651 3173633 SPBio_001381 CC1=C(N2[C@H](SC1)[C@H](NC(=O)C(N)c3ccccc3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F04 compound treatment 270175.0 6130.0 0.12 269485.0 17400.0 0.36 0.3447 0.8978 1298 SPBio_001382 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F05 compound treatment 309400.0 45400.0 0.92 287940.0 35900.0 0.75 1.1788 0.9947 1067 SPBio_001383 CO[C@]1(NC(=O)CSCC#N)C2SCC(=C(N2C1=O)C(=O)O)CSc3nnnn3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F06 compound treatment 287706.0 23700.0 0.48 251777.0 -273.0 -0.01 0.3351 0.6987 3045662 SPBio_001384 CC(N)C(O)c1cccc(O)c1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F07 compound treatment 262128.0 -1920.0 -0.04 289341.0 37300.0 0.78 0.5218 0.6708 3264 SPBio_001385 Cn1nnnc1SCC2=C(N3C(SC2)C(NC(=O)C(OC=O)c4ccccc4)C3=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F08 compound treatment 16573.0 -247000.0 -5.02 7374.0 -245000.0 -5.1 -7.1519 -1.0 3069629 SPBio_001386 CC(=O)/N=c/1\sc(nn1C)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F09 compound treatment 184851.0 -79200.0 -1.61 156975.0 -95100.0 -1.98 -2.5359 -0.9946 1323 SPBio_001387 CC1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F10 compound treatment 5282.0 -259000.0 -5.25 2468.0 -250000.0 -5.2 -7.3861 -1.0 1286 SPBio_001388 Cc1cc(ccc1OCCOCC[N+](C)(C)Cc2ccccc2)C(C)(C)CC(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F11 compound treatment 257610.0 -6440.0 -0.13 249137.0 -2910.0 -0.06 -0.1352 -0.9393 1129 SPBio_001389 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F12 compound treatment 281698.0 17600.0 0.36 277679.0 25600.0 0.53 0.6305 0.981 1535 SPBio_001390 COc1ccc(OC)c(c1)C(O)CNC(=O)CN 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F13 compound treatment 304293.0 40200.0 0.82 272838.0 20800.0 0.43 0.8831 0.9561 2294 SPBio_001391 CC(=O)NC(C(=O)O)C(C)(C)SN=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F14 compound treatment 234920.0 -29100.0 -0.59 212989.0 -39100.0 -0.81 -0.993 -0.9876 1055 SPBio_001392 CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F15 compound treatment 287892.0 23800.0 0.48 260999.0 8950.0 0.19 0.4736 0.9142 366 SPBio_001393 OC(=O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F16 compound treatment 239380.0 -24700.0 -0.5 288242.0 36200.0 0.75 0.1795 0.1984 1163 SPBio_001394 Oc1ccc2C[C@H]3N(CC4CC4)CCC5([C@H]6Oc1c25)[C@@]3(O)CCC6=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F17 compound treatment 289580.0 25500.0 0.52 272768.0 20700.0 0.43 0.6712 0.9959 1591 SPBio_001395 CC(C)C[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F18 compound treatment 232943.0 -31100.0 -0.63 256528.0 4480.0 0.09 -0.3799 -0.596 1386 SPBio_001396 CN1CC(c2ccccc2)c3cccc(N)c3C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F19 compound treatment 246747.0 -17300.0 -0.35 254465.0 2420.0 0.05 -0.2125 -0.5995 348755 SPBio_001397 OC(=O)c1cc2cc(F)ccc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F20 compound treatment 253549.0 -10500.0 -0.21 273212.0 21200.0 0.44 0.1612 0.3293 1436 SPBio_001398 CCCNC(C)C(=O)Nc1ccccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F21 compound treatment 283937.0 19900.0 0.4 302609.0 50600.0 1.05 1.0299 0.9132 873168 SPBio_001399 OC(=O)c1cc(O)c2ccc(Cl)cc2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F22 compound treatment 254827.0 -9220.0 -0.19 245304.0 -6750.0 -0.14 -0.2316 -0.9901 3480197 SPBio_001400 CCC(NC(C)C)C(O)c1ccc(O)c2[nH]c(=O)ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F23 mock treatment 257095.0 -6950.0 -0.14 284669.0 32600.0 0.68 0.3808 0.5487 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 F24 mock treatment 257557.0 -6490.0 -0.13 228572.0 -23500.0 -0.49 -0.4389 -0.8666 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G01 mock treatment 246572.0 -17500.0 -0.35 262606.0 10600.0 0.22 -0.095 -0.2279 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G02 mock treatment 282644.0 18600.0 0.38 272122.0 20100.0 0.42 0.5622 0.9987 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G03 compound treatment 282158.0 18100.0 0.37 273148.0 21100.0 0.44 0.5704 0.996 1264 SPBio_001401 OCc1ccccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G04 compound treatment 268509.0 4460.0 0.09 272957.0 20900.0 0.44 0.3719 0.8361 1438 SPBio_001402 CC(C(=O)O)c1cccc(Oc2ccccc2)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G05 compound treatment 280209.0 16200.0 0.33 267891.0 15800.0 0.33 0.465 1.0 1447 SPBio_001403 NC(=O)c1ccccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G06 compound treatment 364482.0 100000.0 2.04 365723.0 114000.0 2.37 3.1142 0.9972 1036721 SPBio_001404 Oc1c(oc2ccccc2c1=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G07 compound treatment 251600.0 -12400.0 -0.25 295983.0 43900.0 0.92 0.4687 0.4937 933 SPBio_001405 CN1C2C[C@@H](C[C@H]1[C@H]3OC32)OC(=O)[C@H](CO)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G08 compound treatment 264462.0 412.0 0.01 284018.0 32000.0 0.67 0.4768 0.7159 3100 SPBio_001406 COc1c2OCOc2cc3CCN(C)Cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G09 compound treatment 275915.0 11900.0 0.24 253519.0 1470.0 0.03 0.1917 0.7907 3174107 SPBio_001407 CN[C@@H]1C(O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3OC(=CC[C@H]3N)CN)[C@@H]2O)OC[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G10 compound treatment 277161.0 13100.0 0.27 263746.0 11700.0 0.24 0.3603 0.9991 802058 SPBio_001408 COc1cc(/C=C/C(=O)O)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G11 compound treatment 227163.0 -36900.0 -0.75 222994.0 -29100.0 -0.61 -0.9568 -0.9945 795 SPBio_001409 CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G12 compound treatment 270272.0 6220.0 0.13 253805.0 1760.0 0.04 0.1151 0.876 3173760 SPBio_001410 COc1cc2CCN(C)[C@@H]3Cc4cccc(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)c(O)c5)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G13 compound treatment 234342.0 -29700.0 -0.6 278701.0 26700.0 0.56 -0.0333 -0.0406 3059108 SPBio_001411 CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@]54CCC(=O)O5)C13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G14 compound treatment 298905.0 34900.0 0.71 254196.0 2150.0 0.04 0.5313 0.7504 1144 SPBio_001412 O=C1NCC2(CCN(CCc3ccccc3)CC2)O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G15 compound treatment 269999.0 5950.0 0.12 271064.0 19000.0 0.4 0.3654 0.8824 1155 SPBio_001413 Nc1ccc(cc1)S(=O)(=O)NC(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G16 compound treatment 242182.0 -21900.0 -0.44 286235.0 34200.0 0.71 0.1901 0.2266 2081691 SPBio_001414 CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G17 compound treatment 49453.0 -215000.0 -4.35 75893.0 -176000.0 -3.67 -5.6712 -0.9964 878 SPBio_001415 CC(=O)NS(=O)(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G18 compound treatment 2395.0 -262000.0 -5.3 2163.0 -250000.0 -5.21 -7.432 -1.0 1203 SPBio_001416 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@@H]3C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G19 compound treatment 27717.0 -236000.0 -4.79 23627.0 -228000.0 -4.76 -6.7528 -1.0 1159 SPBio_001417 Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G20 compound treatment 263074.0 -976.0 -0.02 263319.0 11300.0 0.23 0.152 0.6453 1346 SPBio_001418 CCN(CC)CCNC(=O)COc1ccc(OC)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G21 compound treatment 32799.0 -231000.0 -4.69 33109.0 -219000.0 -4.56 -6.5402 -0.9999 1177 SPBio_001419 Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G22 compound treatment 270103.0 6050.0 0.12 295861.0 43800.0 0.91 0.7322 0.795 1210 SPBio_001420 CC(C)(C)c1cc(SC(C)(C)Sc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G23 mock treatment 268019.0 3970.0 0.08 284167.0 32100.0 0.67 0.53 0.7865 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 G24 mock treatment 248949.0 -15100.0 -0.31 256341.0 4290.0 0.09 -0.1533 -0.4805 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H01 mock treatment 219548.0 -44500.0 -0.9 231901.0 -20100.0 -0.42 -0.9347 -0.9394 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H02 mock treatment 283149.0 19100.0 0.39 270856.0 18800.0 0.39 0.5508 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H03 compound treatment 293158.0 29100.0 0.59 284291.0 32200.0 0.67 0.8922 0.9979 1364 SPBio_001421 OC(=O)/C(=C/c1cccc(O)c1)/C#N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H04 compound treatment 4665.0 -259000.0 -5.26 2688.0 -249000.0 -5.19 -7.3917 -1.0 3173855 SPBio_001422 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)/C(=N\OCOCCOC)/[C@H](C)[C@@H](O)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H05 compound treatment 267034.0 2980.0 0.06 282685.0 30600.0 0.64 0.4941 0.7707 829 SPBio_001423 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H06 compound treatment 309437.0 45400.0 0.92 261123.0 9070.0 0.19 0.7843 0.8349 1270 SPBio_001424 C[N+](C)(C)CCCCCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H07 compound treatment 296985.0 32900.0 0.67 282896.0 30800.0 0.64 0.9265 0.9998 3061087 SPBio_001425 NC/C=C/C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H08 compound treatment 277288.0 13200.0 0.27 306493.0 54400.0 1.13 0.9918 0.8509 1242 SPBio_001426 CN(CS(=O)(=O)O)c1c(C)n(C)n(c2ccccc2)c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H09 compound treatment 278367.0 14300.0 0.29 255759.0 3710.0 0.08 0.2599 0.8652 3684 SPBio_001427 OC(=O)C1=CCCNC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H10 compound treatment 2806.0 -261000.0 -5.3 1775.0 -250000.0 -5.21 -7.4318 -1.0 1342 SPBio_001428 CN(C)C(=S)SSC(=S)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H11 compound treatment 285468.0 21400.0 0.43 287644.0 35600.0 0.74 0.8314 0.9675 1923 SPBio_001429 NC1(CC1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H12 compound treatment 280343.0 16300.0 0.33 250117.0 -1930.0 -0.04 0.2051 0.6164 3173628 SPBio_001430 CN1C(C)(C)CCCC1(C)C.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H13 compound treatment 269825.0 5780.0 0.12 280951.0 28900.0 0.6 0.5085 0.8291 1111718 SPBio_001431 NC1(CCC1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H14 compound treatment 283210.0 19200.0 0.39 286076.0 34000.0 0.71 0.7759 0.9599 758 SPBio_001432 CCCOc1ccc2nc(NC(=O)OC)[nH]c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H15 compound treatment 218919.0 -45100.0 -0.91 218288.0 -33800.0 -0.7 -1.1443 -0.9916 121 SPBio_001433 OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H16 compound treatment 213467.0 -50600.0 -1.03 259748.0 7700.0 0.16 -0.6117 -0.5894 1410 SPBio_001434 S=P(N1CC1)(N2CC2)N3CC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H17 compound treatment 310120.0 46100.0 0.93 273693.0 21600.0 0.45 0.9793 0.9442 1594 SPBio_001435 N[C@@H](CCCNC(=N)N[N+](=O)[O-])C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H18 compound treatment 277116.0 13100.0 0.26 270792.0 18700.0 0.39 0.4634 0.9821 1080 SPBio_001436 N[C@H](Cc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H19 compound treatment 271795.0 7750.0 0.16 274919.0 22900.0 0.48 0.4479 0.8929 1458 SPBio_001437 NC(Cc1ccc(Cl)cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H20 compound treatment 291190.0 27100.0 0.55 314987.0 62900.0 1.31 1.3162 0.9256 1528 SPBio_001438 NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H21 compound treatment 271549.0 7500.0 0.15 271424.0 19400.0 0.4 0.3929 0.911 3198954 SPBio_001439 CC[C@H](C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H22 compound treatment 178754.0 -85300.0 -1.73 183103.0 -68900.0 -1.44 -2.2384 -0.9957 846 SPBio_001440 Cc1nc2sccn2c(=O)c1CCN3CCC(=C(c4ccc(F)cc4)c5ccc(F)cc5)CC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H23 mock treatment 286583.0 22500.0 0.46 248204.0 -3850.0 -0.08 0.2664 0.5743 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 H24 mock treatment 255510.0 -8540.0 -0.17 266696.0 14600.0 0.31 0.0933 0.2661 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I01 mock treatment 259975.0 -4070.0 -0.08 229448.0 -22600.0 -0.47 -0.3914 -0.8187 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I02 mock treatment 258555.0 -5490.0 -0.11 248816.0 -3230.0 -0.07 -0.1264 -0.971 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I03 compound treatment 107266.0 -157000.0 -3.18 102880.0 -149000.0 -3.11 -4.4449 -0.9999 934 SPBio_001441 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I04 compound treatment 279887.0 15800.0 0.32 299034.0 47000.0 0.98 0.9192 0.8923 1350 SPBio_001442 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I05 compound treatment 12026.0 -252000.0 -5.11 11982.0 -240000.0 -5.0 -7.1492 -0.9999 799 SPBio_001443 Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I06 compound treatment 295917.0 31900.0 0.65 265950.0 13900.0 0.29 0.6616 0.9345 1233 SPBio_001444 CO[C@@H]1[C@@H](O)[C@H](C)O[C@H](O[C@H]2CC[C@@]3(C=O)[C@H](CCC4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I07 compound treatment 79676.0 -184000.0 -3.74 84332.0 -168000.0 -3.49 -5.1137 -0.9994 867 SPBio_001445 Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I08 compound treatment 277629.0 13600.0 0.28 294411.0 42400.0 0.88 0.8187 0.8856 3173860 SPBio_001446 O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5OC1[C@]2(CCN3CC6CCC6)c54 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I09 compound treatment 264414.0 364.0 0.01 296367.0 44300.0 0.92 0.6581 0.7127 753 SPBio_001447 O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I10 compound treatment 250949.0 -13100.0 -0.27 300321.0 48300.0 1.01 0.5233 0.5031 714 SPBio_001448 CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc2ccc(OC)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I11 compound treatment 19671.0 -244000.0 -4.95 14679.0 -237000.0 -4.95 -6.9999 -1.0 1192 SPBio_001449 Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I12 compound treatment 2734.0 -261000.0 -5.3 2539.0 -250000.0 -5.2 -7.4216 -1.0 3174345 SPBio_001450 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@@H]3C(=C)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N.OC(=O)c1cc(ccc1O)S(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I13 compound treatment 283602.0 19600.0 0.4 275737.0 23700.0 0.49 0.6292 0.9941 1212 SPBio_001451 CC/1=C(CC(=O)O)c2cc(F)ccc2\C1=C/c3ccc(cc3)S(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I14 compound treatment 261971.0 -2080.0 -0.04 307375.0 55300.0 1.15 0.7852 0.6808 1291 SPBio_001452 CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I15 compound treatment 242081.0 -22000.0 -0.45 289338.0 37300.0 0.78 0.2344 0.2617 743 SPBio_001453 CC(C)(C)NCC(O)c1cc(O)cc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I16 compound treatment 210959.0 -53100.0 -1.08 286314.0 34300.0 0.71 -0.2563 -0.1985 728 SPBio_001454 Cc1cc(nnc1NCCN2CCOCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I17 compound treatment 273395.0 9350.0 0.19 271567.0 19500.0 0.41 0.4215 0.9396 1218 SPBio_001455 CCCCNc1ccc(cc1)C(=O)OCCN(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I18 compound treatment 91075.0 -173000.0 -3.51 235435.0 -16600.0 -0.35 -2.7244 -0.7731 733 SPBio_001456 CC1(CC2CC3(C)C1)CC(N)(C2)C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I19 compound treatment 2641.0 -261000.0 -5.3 2072.0 -250000.0 -5.21 -7.4298 -1.0 1418 SPBio_001457 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I20 compound treatment 283268.0 19200.0 0.39 312420.0 60400.0 1.26 1.1648 0.8847 983 SPBio_001458 NCCCS(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I21 compound treatment 249974.0 -14100.0 -0.29 289682.0 37600.0 0.78 0.3526 0.4226 1444 SPBio_001459 C1CN=C(N1)C2CCCc3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I22 compound treatment 283900.0 19900.0 0.4 253775.0 1730.0 0.04 0.31 0.7672 840551 SPBio_001460 NCCCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I23 mock treatment 250979.0 -13100.0 -0.26 250551.0 -1500.0 -0.03 -0.2094 -0.785 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 I24 mock treatment 287182.0 23100.0 0.47 273581.0 21500.0 0.45 0.6488 0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J01 mock treatment 276172.0 12100.0 0.25 253548.0 1500.0 0.03 0.1958 0.7906 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J02 mock treatment 276664.0 12600.0 0.26 254239.0 2190.0 0.05 0.2131 0.8203 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J03 compound treatment 291731.0 27700.0 0.56 293958.0 41900.0 0.87 1.0142 0.9772 3471022 SPBio_001461 CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J04 compound treatment 2924.0 -261000.0 -5.29 2637.0 -249000.0 -5.2 -7.4174 -1.0 3173083 SPBio_001462 CO[C@H]1[C@H](O)CC(=O)O[C@@H](C)C/C=C/C=C/[C@H](O[C@H]2CC[C@@H]([C@@H](C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@@H]3O[C@H](C)[C@@H](O[C@H]4C[C@@](C)(O)[C@H](O)[C@H](C)O4)[C@@H]([C@H]3O)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J05 compound treatment 286962.0 22900.0 0.46 288119.0 36100.0 0.75 0.8598 0.9733 1581 SPBio_001463 CNC(=N)NCCCC(N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J06 compound treatment 278924.0 14900.0 0.3 269006.0 17000.0 0.35 0.463 0.9969 115 SPBio_001464 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J07 compound treatment 323734.0 59700.0 1.21 279360.0 27300.0 0.57 1.2579 0.9408 869 SPBio_001465 CCC1(C)CC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J08 compound treatment 265235.0 1190.0 0.02 269530.0 17500.0 0.36 0.2745 0.7521 839 SPBio_001466 Nc1nc2n(COCCO)cnc2c(=O)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J09 compound treatment 280071.0 16000.0 0.32 252723.0 673.0 0.01 0.2396 0.737 3172968 SPBio_001467 CCC1NC(=O)C(C(O)C(C)C/C=C/C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J10 compound treatment 263364.0 -686.0 -0.01 284172.0 32100.0 0.67 0.4634 0.6923 897 SPBio_001468 CCCCCCCCCCCCCCCC(=O)OC/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J11 compound treatment 6305.0 -258000.0 -5.23 3642.0 -248000.0 -5.18 -7.3541 -1.0 3173475 SPBio_001469 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](OC3O[C@H](C)C[C@@H]([C@H]3OC(=O)C)N(C)C)[C@@H](C)C[C@]4(CO4)C(=O)[C@H](C)[C@@H](OC(=O)C)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J12 compound treatment 223320.0 -40700.0 -0.83 258146.0 6100.0 0.13 -0.4941 -0.5914 117 SPBio_001470 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J13 compound treatment 295692.0 31600.0 0.64 302942.0 50900.0 1.06 1.2033 0.971 3198430 SPBio_001471 CC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(F)(F)F)C(C)C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J14 compound treatment 2498.0 -262000.0 -5.3 2685.0 -249000.0 -5.19 -7.4228 -0.9999 1417 SPBio_001472 CCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J15 compound treatment 270646.0 6600.0 0.13 247707.0 -4340.0 -0.09 0.0306 0.1895 3079212 SPBio_001473 NCCCN.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J16 compound treatment 161850.0 -102000.0 -2.07 176509.0 -75500.0 -1.57 -2.5778 -0.9908 757 SPBio_001474 OC(=O)c1cn(C2CC2)c3cc(N4CCNCC4)c(F)cc3c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J17 compound treatment 266266.0 2220.0 0.04 285206.0 33200.0 0.69 0.5202 0.7515 3198431 SPBio_001475 CC(C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J18 compound treatment 260121.0 -3930.0 -0.08 241215.0 -10800.0 -0.23 -0.2159 -0.9021 1038 SPBio_001476 O=C1CCCN1CC#CCN2CCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J19 compound treatment 270917.0 6870.0 0.14 275573.0 23500.0 0.49 0.445 0.8734 1095029 SPBio_001477 CCCCCCCCCCCCCCCCCCOP(=O)(O)OCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J20 compound treatment 207590.0 -56500.0 -1.14 256130.0 4080.0 0.09 -0.7492 -0.6528 382 SPBio_001478 NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J21 compound treatment 292694.0 28600.0 0.58 289001.0 37000.0 0.77 0.955 0.9903 3079213 SPBio_001479 N[C@@H](CCC(=O)N[C@@H](CCSC(CC(=O)O)C(=O)O)C(=O)NCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J22 compound treatment 296749.0 32700.0 0.66 253287.0 1240.0 0.03 0.487 0.7341 1512 SPBio_001480 CC(C)NCC(O)c1ccc2ccccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J23 mock treatment 250119.0 -13900.0 -0.28 261626.0 9580.0 0.2 -0.0586 -0.1695 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 J24 mock treatment 276175.0 12100.0 0.25 251234.0 -816.0 -0.02 0.1618 0.6567 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K01 mock treatment 273341.0 9290.0 0.19 246137.0 -5910.0 -0.12 0.0461 0.2048 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K02 mock treatment 243297.0 -20800.0 -0.42 291691.0 39600.0 0.83 0.2865 0.3091 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K03 compound treatment 344738.0 80700.0 1.64 326463.0 74400.0 1.55 2.2529 0.9996 737 SPBio_001481 c1nc(cs1)c2nc3ccccc3[nH]2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K04 compound treatment 307798.0 43700.0 0.89 273617.0 21600.0 0.45 0.9449 0.9503 723 SPBio_001482 CC(C)NCC(O)COc1ccc(CC(=O)N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K05 compound treatment 237320.0 -26700.0 -0.54 270465.0 18400.0 0.38 -0.1119 -0.1685 731 SPBio_001483 CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K06 compound treatment 2968.0 -261000.0 -5.29 53352.0 -199000.0 -4.14 -6.6697 -0.9926 990 SPBio_001484 CCN(CC)CCOCCOC(=O)C1(CCCC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K07 compound treatment 300472.0 36400.0 0.74 284479.0 32400.0 0.68 0.9998 0.999 972 SPBio_001485 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3/C(=C\CCN4CCN(C)CC4)/c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K08 compound treatment 299514.0 35500.0 0.72 301580.0 49500.0 1.03 1.238 0.9844 338 SPBio_001486 Nc1ccncc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K09 compound treatment 249206.0 -14800.0 -0.3 306023.0 54000.0 1.12 0.5823 0.5003 833 SPBio_001487 CC(C)(C)NC[C@@H](O)COc1nsnc1N2CCOCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K10 compound treatment 241223.0 -22800.0 -0.46 273559.0 21500.0 0.45 -0.0104 -0.0161 783 SPBio_001488 CO[C@@]12C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]2Cc4cn(C)c5cccc1c45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K11 compound treatment 314280.0 50200.0 1.02 275514.0 23500.0 0.49 1.0657 0.9435 2572 SPBio_001489 COc1cc2CC[N+](C)(C)[C@@H]3Cc4ccc(O)c(Oc5cc6[C@H](Cc7ccc(Oc(c1O)c32)cc7)N(C)CCc6cc5OC)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K12 compound treatment 216783.0 -47300.0 -0.96 229466.0 -22600.0 -0.47 -1.0103 -0.9464 86 SPBio_001490 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K13 compound treatment 240895.0 -23200.0 -0.47 191904.0 -60100.0 -1.25 -1.2179 -0.9102 1000109 SPBio_001491 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K14 compound treatment 264898.0 848.0 0.02 273004.0 21000.0 0.44 0.3208 0.7344 1016 SPBio_001492 CN1CCOC(c2ccccc2)c3ccccc3C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K15 compound treatment 2640.0 -261000.0 -5.3 5162.0 -247000.0 -5.14 -7.3843 -0.9999 883 SPBio_001493 CC(Oc1ccccc1)C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K16 compound treatment 304473.0 40400.0 0.82 258849.0 6800.0 0.14 0.6796 0.8172 786 SPBio_001494 CN1CCN(CC(=O)N2c3ccccc3C(=O)Nc4cccnc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K17 compound treatment 258348.0 -5700.0 -0.12 268737.0 16700.0 0.35 0.1641 0.4479 824 SPBio_001495 CC[C@]1(CCCN2CCc3c4[C@@H]21)C[C@@](O)(C(=O)OC)n4c5ccccc35 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K18 compound treatment 292898.0 28800.0 0.58 273727.0 21700.0 0.45 0.7329 0.9918 741 SPBio_001496 Cc1ccccc1OCC(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K19 compound treatment 270809.0 6760.0 0.14 283186.0 31100.0 0.65 0.5556 0.838 1052 SPBio_001497 CC[C@H]1CN2CCC1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K20 compound treatment 22812.0 -241000.0 -4.89 23101.0 -229000.0 -4.77 -6.8308 -0.9999 751 SPBio_001498 COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K21 compound treatment 276080.0 12000.0 0.24 266294.0 14200.0 0.3 0.3823 0.9953 1223 SPBio_001499 CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K22 compound treatment 273570.0 9520.0 0.19 283080.0 31000.0 0.65 0.5936 0.8798 1241 SPBio_001500 NC(=N)NS(=O)(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K23 mock treatment 270710.0 6660.0 0.14 292466.0 40400.0 0.84 0.6909 0.8101 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 K24 mock treatment 266544.0 2490.0 0.05 232409.0 -19600.0 -0.41 -0.2536 -0.615 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L01 mock treatment 254077.0 -9970.0 -0.2 246951.0 -5100.0 -0.11 -0.2181 -0.9548 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L02 mock treatment 273158.0 9110.0 0.18 273145.0 21100.0 0.44 0.4413 0.9258 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L03 compound treatment 301790.0 37700.0 0.77 305542.0 53500.0 1.11 1.329 0.9832 3198432 SPBio_001501 CSC(=N)NCCC[C@@H](N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L04 compound treatment 354437.0 90400.0 1.83 300476.0 48400.0 1.01 2.0091 0.9605 1269 SPBio_001502 CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L05 compound treatment 294880.0 30800.0 0.63 295800.0 43800.0 0.91 1.0865 0.9831 3198433 SPBio_001503 NC(Cc1c[nH]cn1)C(=O)Nc2ccc3ccccc3c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L06 compound treatment 359294.0 95200.0 1.93 298194.0 46100.0 0.96 2.0451 0.9481 1486 SPBio_001504 CC(C)NCC(O)COc1ccc(NC(=O)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L07 compound treatment 7540.0 -257000.0 -5.2 7427.0 -245000.0 -5.1 -7.2807 -0.9999 3176939 SPBio_001505 ClCC(=O)[C@H](Cc1ccccc1)NC(=O)OCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L08 compound treatment 230575.0 -33500.0 -0.68 267707.0 15700.0 0.33 -0.2492 -0.331 1415 SPBio_001506 FC(F)(F)c1cccc(c1)N2CCNCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L09 compound treatment 279123.0 15100.0 0.31 290640.0 38600.0 0.8 0.7846 0.9122 3198434 SPBio_001507 NCCCC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L10 compound treatment 286426.0 22400.0 0.45 277719.0 25700.0 0.53 0.6989 0.9966 419 SPBio_001508 CC1=NN(C(=O)C1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L11 compound treatment 319067.0 55000.0 1.12 303575.0 51500.0 1.07 1.5477 0.9998 3079214 SPBio_001509 CC(C)CC(NC(=O)CN)C(=O)NC(Cc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L12 compound treatment 264707.0 657.0 0.01 260835.0 8790.0 0.18 0.1388 0.7566 907188 SPBio_001510 COc1cccc(OC)c1OCCNCC2COc3ccccc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L13 compound treatment 285572.0 21500.0 0.44 267574.0 15500.0 0.32 0.5372 0.9891 3198435 SPBio_001511 N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L14 compound treatment 261096.0 -2950.0 -0.06 277808.0 25800.0 0.54 0.3371 0.6243 1478 SPBio_001512 Cc1ccc(cc1)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L15 compound treatment 217096.0 -47000.0 -0.95 215764.0 -36300.0 -0.76 -1.2076 -0.9935 2269 SPBio_001513 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L16 compound treatment 264568.0 518.0 0.01 302109.0 50100.0 1.04 0.7449 0.7142 445 SPBio_001514 NC(=O)c1cccc(N)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L17 compound treatment 317630.0 53600.0 1.09 295318.0 43300.0 0.9 1.4055 0.9957 3054972 SPBio_001515 CC(C)C1=CC2=CCC3[C@](C)(CCC[C@]3(C)C2CC1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L18 compound treatment 269941.0 5890.0 0.12 295606.0 43600.0 0.91 0.7261 0.7933 1248 SPBio_001516 C[C@@]12CCC3C(CCc4cc(OC(=O)CCC(=O)O)ccc34)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L19 compound treatment 282744.0 18700.0 0.38 281148.0 29100.0 0.61 0.6966 0.9744 3079215 SPBio_001517 CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L20 compound treatment 310896.0 46800.0 0.95 290137.0 38100.0 0.79 1.2326 0.996 2060318 SPBio_001518 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@]12O[C@]2(C)C[C@@H](O)CC1(C)C)/C=C/C=C(\C)/C=C/C3=C(C)C[C@@H](O)CC3(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L21 compound treatment 318021.0 54000.0 1.09 328675.0 76600.0 1.6 1.9025 0.983 740 SPBio_001519 N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L22 compound treatment 268659.0 4610.0 0.09 284825.0 32800.0 0.68 0.5489 0.7965 1023 SPBio_001520 CN[C@H](CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L23 mock treatment 302480.0 38400.0 0.78 258060.0 6010.0 0.13 0.6394 0.8104 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 L24 mock treatment 266223.0 2170.0 0.04 254160.0 2110.0 0.04 0.0622 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M01 mock treatment 284287.0 20200.0 0.41 254423.0 2370.0 0.05 0.3251 0.7866 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M02 mock treatment 302782.0 38700.0 0.79 250419.0 -1630.0 -0.03 0.5312 0.6759 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M03 compound treatment 290677.0 26600.0 0.54 289337.0 37300.0 0.78 0.931 0.9842 2069343 SPBio_001521 COc1ccc2[C@H](OC(=O)c2c1OC)[C@H]3N(C)CCc4cc5OCOc5cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M04 compound treatment 17889.0 -246000.0 -4.99 14995.0 -237000.0 -4.94 -7.0208 -1.0 1529 SPBio_001522 COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M05 compound treatment 326532.0 62500.0 1.27 336915.0 84900.0 1.77 2.1459 0.9866 949 SPBio_001523 OC(=O)c1cc(O)c2ccccc2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M06 compound treatment 31468.0 -233000.0 -4.72 26173.0 -226000.0 -4.71 -6.6615 -1.0 871 SPBio_001524 Clc1ccc(CSC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M07 compound treatment 299811.0 35800.0 0.72 279842.0 27800.0 0.58 0.9221 0.9938 362 SPBio_001525 CCN(CC)CC(=O)Nc1c(C)cccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M08 compound treatment 143596.0 -120000.0 -2.44 184138.0 -67900.0 -1.41 -2.7271 -0.9663 3480067 SPBio_001526 CC(NCCc1ccc(O)cc1)C(O)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M09 compound treatment 256818.0 -7230.0 -0.15 296875.0 44800.0 0.93 0.5567 0.5889 988 SPBio_001527 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M10 compound treatment 238871.0 -25200.0 -0.51 305118.0 53100.0 1.11 0.4208 0.3456 3058009 SPBio_001528 CCN1CCC(CNC(=O)c2cc(ccc2OC)S(=O)(=O)N)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M11 compound treatment 282686.0 18600.0 0.38 285739.0 33700.0 0.7 0.7634 0.9578 898 SPBio_001529 CCOC(=O)C(Cc1ccc(O)cc1)NC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M12 compound treatment 289579.0 25500.0 0.52 262075.0 10000.0 0.21 0.5137 0.9203 1068 SPBio_001530 CN/C(=C\[N+](=O)[O-])/NCCSCc1ccc(CN(C)C)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M13 compound treatment 269096.0 5050.0 0.1 304396.0 52300.0 1.09 0.8435 0.7701 993 SPBio_001531 CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M14 compound treatment 252180.0 -11900.0 -0.24 286131.0 34100.0 0.71 0.3319 0.4427 1180 SPBio_001532 Fc1ccc(cc1)C(=O)CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M15 compound treatment 268897.0 4850.0 0.1 297970.0 45900.0 0.96 0.7459 0.7757 1073 SPBio_001533 CC(N)C(=O)NC(Cc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M16 compound treatment 220980.0 -43100.0 -0.87 312111.0 60100.0 1.25 0.2674 0.1752 998 SPBio_001534 CCCCCCCCNC(C)C(O)c1ccc(SC(C)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M17 compound treatment 260043.0 -4010.0 -0.08 290214.0 38200.0 0.8 0.5048 0.6316 1017 SPBio_001535 CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M18 compound treatment 89019.0 -175000.0 -3.55 62101.0 -190000.0 -3.96 -5.3072 -0.9985 1094 SPBio_001536 COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M19 compound treatment 291943.0 27900.0 0.57 292165.0 40100.0 0.84 0.9908 0.9819 1034 SPBio_001537 CC(=O)N[C@@H](CCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M20 compound treatment 160266.0 -104000.0 -2.1 113564.0 -138000.0 -2.89 -3.5278 -0.988 887 SPBio_001538 COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M21 compound treatment 265982.0 1930.0 0.04 254419.0 2370.0 0.05 0.0626 0.9934 1523 SPBio_001539 CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M22 compound treatment 288354.0 24300.0 0.49 250285.0 -1760.0 -0.04 0.3224 0.6525 1102 SPBio_001540 CC(C(=O)O)c1ccc(cc1)C(=O)c2cccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M23 mock treatment 253566.0 -10500.0 -0.21 241670.0 -10400.0 -0.22 -0.3032 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 M24 mock treatment 256842.0 -7210.0 -0.15 246650.0 -5400.0 -0.11 -0.1829 -0.9916 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N01 mock treatment 314929.0 50900.0 1.03 280232.0 28200.0 0.59 1.1445 0.9643 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N02 mock treatment 323430.0 59400.0 1.2 284042.0 32000.0 0.67 1.3225 0.9611 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N03 compound treatment 353669.0 89600.0 1.82 411563.0 160000.0 3.32 3.6345 0.9596 3054980 SPBio_001541 Nc1ncnc2n(cnc12)C3C[C@H](O)[C@@H](CO)O3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N04 compound treatment 284830.0 20800.0 0.42 314885.0 62800.0 1.31 1.2235 0.8897 3174610 SPBio_001542 COc1cc(cc(OC)c1OC)C(=O)O[C@H]2CC[C@@]3(C)[C@@H]4CC[C@@H]5[C@@]3(C[C@@]6(O)[C@@H]7CN8C[C@@H](C)CC[C@H]8[C@@](C)(O)[C@@]7(O)[C@@H](O)C[C@@]56O)O[C@@]42O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N05 compound treatment 291720.0 27700.0 0.56 271215.0 19200.0 0.4 0.679 0.9861 2060304 SPBio_001543 OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N06 compound treatment 7965.0 -256000.0 -5.19 2558.0 -249000.0 -5.2 -7.3463 -1.0 882 SPBio_001544 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N07 compound treatment 293675.0 29600.0 0.6 270349.0 18300.0 0.38 0.6943 0.9759 2060308 SPBio_001545 C/C(=C/C(=O)O)/C=C/C1(O)C(=CC(=O)CC1(C)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N08 compound treatment 3038.0 -261000.0 -5.29 4018.0 -248000.0 -5.17 -7.3954 -0.9999 3198436 SPBio_001546 CO[C@H]1CC(O[C@H]/2[C@@H](C)\C=C\C=C\3/CO[C@@H]4\C(=N/O)\C(=C[C@@H](C(=O)O[C@H]5C[C@@H](C\C=C2/C)O[C@@]6(CC[C@H](C)[C@H](O6)C7CCCCC7)C5)[C@@]43O)C)O[C@@H](C)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N09 compound treatment 326183.0 62100.0 1.26 295428.0 43400.0 0.9 1.5297 0.9867 1039 SPBio_001547 CC[C@]1(CCCN2CCc3c4[C@@H]21)CC(=O)n4c5ccccc35 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N10 compound treatment 216726.0 -47300.0 -0.96 213125.0 -38900.0 -0.81 -1.2518 -0.9965 1389 SPBio_001548 CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc4cccnc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N11 compound treatment 252990.0 -11100.0 -0.22 258714.0 6660.0 0.14 -0.0604 -0.2289 1583 SPBio_001549 COc1ccc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N12 compound treatment 278018.0 14000.0 0.28 265053.0 13000.0 0.27 0.3918 0.9998 3174609 SPBio_001550 CC(C)c1c(C(=O)c2ccccc2)c(c(c3ccc(F)cc3)n1CC[C@@H](O)C[C@@H](O)CC(=O)O)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N13 compound treatment 211291.0 -52800.0 -1.07 252713.0 663.0 0.01 -0.7465 -0.6979 1010348 SPBio_001551 OC1=CC(=O)c2ccccc2C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N14 compound treatment 272641.0 8590.0 0.17 291838.0 39800.0 0.83 0.7093 0.8374 3172973 SPBio_001552 COC(=O)[C@@]1(O)OC[C@]2(C3[C@H]4OC[C@@]3([C@@H](C[C@@H]2OC(=O)/C(=C/C)/C)OC(=O)C)C(=O)OC)[C@@H]1[C@@](C)([C@@H]4O)C56O[C@@]6(C)[C@H]7C[C@@H]5OC8OC=C[C@]78O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N15 compound treatment 283604.0 19600.0 0.4 287255.0 35200.0 0.73 0.7989 0.9583 3054057 SPBio_001553 CC(=CCC/C(=C/CCC(C)(O)C=C)/C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N16 compound treatment 12764.0 -251000.0 -5.09 15190.0 -237000.0 -4.93 -7.0914 -0.9999 1520 SPBio_001554 CC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N17 compound treatment 236563.0 -27500.0 -0.56 283294.0 31200.0 0.65 0.0662 0.0773 1002002 SPBio_001555 O[C@@H]1CC(=C[C@@H](O)[C@H]1O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N18 compound treatment 269092.0 5040.0 0.1 236714.0 -15300.0 -0.32 -0.1536 -0.458 1457 SPBio_001556 CC(=O)OCC(=O)[C@]12OC3(CCCC3)O[C@@H]2CC4C5CCC6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@@]41C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N19 compound treatment 120280.0 -144000.0 -2.91 78915.0 -173000.0 -3.61 -4.6114 -0.9944 797 SPBio_001557 CC[C@]1(CC[C@@H](O1)[C@]2(C)CCC3(C[C@H](O)[C@@H](C)[C@H](O3)[C@H](C)[C@@H](OC)[C@H](C)C(=O)O)O2)C4O[C@H](C[C@@H]4C)C5O[C@@](O)(CC)[C@H](C)C[C@@H]5C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N20 compound treatment 283366.0 19300.0 0.39 289807.0 37800.0 0.79 0.8331 0.9481 1357 SPBio_001558 CCCCN1CCCCC1C(=O)Nc2c(C)cccc2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N21 compound treatment 284806.0 20800.0 0.42 260502.0 8450.0 0.18 0.4221 0.9253 1000111 SPBio_001559 OC(=O)CCCCC1SCC2NC(=O)NC12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N22 compound treatment 290747.0 26700.0 0.54 226389.0 -25700.0 -0.53 0.0047 0.0062 864 SPBio_001560 Oc1noc2CNCCc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N23 mock treatment 279549.0 15500.0 0.31 246228.0 -5820.0 -0.12 0.1364 0.4051 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 N24 mock treatment 227843.0 -36200.0 -0.73 212019.0 -40000.0 -0.83 -1.1087 -0.998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O01 mock treatment 272113.0 8060.0 0.16 256524.0 4470.0 0.09 0.1815 0.9645 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O02 mock treatment 273777.0 9730.0 0.2 255462.0 3410.0 0.07 0.1897 0.905 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O03 compound treatment 268796.0 4750.0 0.1 255286.0 3240.0 0.07 0.1157 0.9849 1407 SPBio_001561 NC(COCc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O04 compound treatment 265980.0 1930.0 0.04 250294.0 -1760.0 -0.04 0.0018 0.0338 1237 SPBio_001562 CC(=O)Nc1ccc(OC(=O)c2ccccc2O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O05 compound treatment 281680.0 17600.0 0.36 256655.0 4610.0 0.1 0.3206 0.8663 1026 SPBio_001563 CC(=O)NC(Cc1ccccc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O06 compound treatment 282614.0 18600.0 0.38 328722.0 76700.0 1.6 1.3956 0.8504 821 SPBio_001564 O=C1NS(=O)(=O)c2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O07 compound treatment 275978.0 11900.0 0.24 260107.0 8060.0 0.17 0.2897 0.9841 987 SPBio_001565 CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O08 compound treatment 275833.0 11800.0 0.24 304267.0 52200.0 1.09 0.9381 0.8423 1122 SPBio_001566 N(=Nc1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O09 compound treatment 277616.0 13600.0 0.28 288221.0 36200.0 0.75 0.7273 0.9067 874 SPBio_001567 CC(C)CC(NC(=O)CCN)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O10 compound treatment 289665.0 25600.0 0.52 271632.0 19600.0 0.41 0.6557 0.9929 738 SPBio_001568 CC(=O)Nc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O11 compound treatment 241780.0 -22300.0 -0.45 221286.0 -30800.0 -0.64 -0.7724 -0.9853 2060457 SPBio_001569 COc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O12 compound treatment 30966.0 -233000.0 -4.73 22701.0 -229000.0 -4.78 -6.7198 -1.0 684 SPBio_001570 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3OC(=O)CC)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O13 compound treatment 244618.0 -19400.0 -0.39 250335.0 -1710.0 -0.04 -0.3038 -0.7681 1006104 SPBio_001571 Cc1cc(=O)oc2cc(O)cc(O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O14 compound treatment 243931.0 -20100.0 -0.41 288827.0 36800.0 0.77 0.2534 0.2919 3059431 SPBio_001572 CCC(=O)O[C@H]1CCC2C3CCc4cc(O)ccc4C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O15 compound treatment 281635.0 17600.0 0.36 251128.0 -922.0 -0.02 0.2385 0.6681 2060475 SPBio_001573 COc1cc(OC)c2C(=O)CC(Oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O16 compound treatment 247826.0 -16200.0 -0.33 263054.0 11000.0 0.23 -0.0705 -0.1757 813 SPBio_001574 CC(=O)O[C@H]1CCC2C3CCc4cc(OC(=O)C)ccc4C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O17 compound treatment 285823.0 21800.0 0.44 261506.0 9460.0 0.2 0.4514 0.9339 2060277 SPBio_001575 COc1cccc2c(=O)c(OC)c(oc12)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O18 compound treatment 331271.0 67200.0 1.36 279326.0 27300.0 0.57 1.3654 0.9248 3177458 SPBio_001576 CC(=O)Oc1ccc2C3CC[C@@]4(C)C(CCC4=O)C3CCc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O19 compound treatment 260025.0 -4020.0 -0.08 285853.0 33800.0 0.7 0.4403 0.621 1554635 SPBio_001577 COc1cc(OC)c2c(=O)cc(oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O20 compound treatment 48902.0 -215000.0 -4.36 4360.0 -248000.0 -5.16 -6.7329 -0.9965 773 SPBio_001578 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O21 compound treatment 267292.0 3240.0 0.07 242634.0 -9420.0 -0.2 -0.0922 -0.4458 724 SPBio_001579 CCn1cc(C(=O)O)c(=O)c2ccc(C)nc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O22 compound treatment 299622.0 35600.0 0.72 279807.0 27800.0 0.58 0.9188 0.994 782 SPBio_001580 CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)C=CC5(C)C4C(O)CC3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O23 mock treatment 316715.0 52700.0 1.07 239317.0 -12700.0 -0.27 0.5674 0.5158 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 O24 mock treatment 266815.0 2770.0 0.06 260989.0 8940.0 0.19 0.1713 0.8809 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P01 mock treatment 291272.0 27200.0 0.55 263347.0 11300.0 0.24 0.5567 0.9278 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P02 mock treatment 268772.0 4720.0 0.1 271607.0 19600.0 0.41 0.3558 0.8501 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P03 compound treatment 238007.0 -26000.0 -0.53 236938.0 -15100.0 -0.31 -0.5959 -0.9695 1255 SPBio_001581 NC(=O)c1ccc(cc1Cl)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P04 compound treatment 294109.0 30100.0 0.61 277886.0 25800.0 0.54 0.8115 0.9981 1419 SPBio_001582 NCCSSCCN 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P05 compound treatment 127824.0 -136000.0 -2.76 126254.0 -126000.0 -2.62 -3.8059 -0.9997 1263 SPBio_001583 C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P06 compound treatment 274389.0 10300.0 0.21 250435.0 -1610.0 -0.03 0.1244 0.5861 1524 SPBio_001584 CC(C)Nc1c(C)n(C)n(c2ccccc2)c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P07 compound treatment 244794.0 -19300.0 -0.39 273841.0 21800.0 0.45 0.045 0.0751 1424 SPBio_001585 CCCC(=O)Nc1ncnc2n(cnc12)C3O[C@@H]4COP(=O)(O)O[C@H]4[C@H]3OC(=O)CCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P08 compound treatment 306596.0 42500.0 0.86 300456.0 48400.0 1.01 1.323 0.997 1452 SPBio_001586 CCCCN(CCCC)CCCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P09 compound treatment 278112.0 14100.0 0.29 263724.0 11700.0 0.24 0.3736 0.9969 1246 SPBio_001587 CC[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P10 compound treatment 279378.0 15300.0 0.31 248715.0 -3330.0 -0.07 0.1706 0.5358 1493 SPBio_001588 CCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P11 compound treatment 62431.0 -202000.0 -4.09 66665.0 -185000.0 -3.86 -5.6211 -0.9996 1299 SPBio_001589 Nc1ccc(cc1)C(=O)NCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P12 compound treatment 270577.0 6530.0 0.13 267208.0 15200.0 0.32 0.3169 0.9254 1526 SPBio_001590 CC1CCCC(C)N1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P13 compound treatment 6972.0 -257000.0 -5.21 29910.0 -222000.0 -4.63 -6.9576 -0.9982 1387 SPBio_001591 OC(C1CCCCN1)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P14 compound treatment 230720.0 -33300.0 -0.68 244382.0 -7670.0 -0.16 -0.5907 -0.8508 1431 SPBio_001592 Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P15 compound treatment 250073.0 -14000.0 -0.28 262919.0 10900.0 0.23 -0.0402 -0.1109 872 SPBio_001593 CCN(CC)CCOC(=O)C(c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P16 compound treatment 251786.0 -12300.0 -0.25 239967.0 -12100.0 -0.25 -0.3538 -1.0 3045655 SPBio_001594 CC(=O)[C@@]1(O)CCC2C3C=C(Cl)C4=CC(=O)[C@@H]5CC5[C@]4(C)C3CC[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P17 compound treatment 236755.0 -27300.0 -0.55 224117.0 -27900.0 -0.58 -0.8027 -0.9997 701 SPBio_001595 Nc1c(Br)cc(Br)cc1CNC2CCC(O)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P18 compound treatment 255623.0 -8430.0 -0.17 238977.0 -13100.0 -0.27 -0.3134 -0.9748 3172846 SPBio_001596 NC(CO)(CO)CO.OC(=O)C1CCn2c(ccc12)C(=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P19 compound treatment 294313.0 30300.0 0.61 235661.0 -16400.0 -0.34 0.1924 0.274 3174106 SPBio_001597 CN(C)CCCO[C@H]1[C@H](OC2OC(C)(C)O[C@H]12)C(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P20 compound treatment 291247.0 27200.0 0.55 206551.0 -45500.0 -0.95 -0.2804 -0.2557 1453 SPBio_001598 CN1CCCN=C1/C=C/c2sccc2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P21 compound treatment 284009.0 20000.0 0.4 235400.0 -16600.0 -0.35 0.0409 0.0767 818 SPBio_001599 CCC1(CC)C(=O)NC=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P22 compound treatment 228410.0 -35600.0 -0.72 241436.0 -10600.0 -0.22 -0.6672 -0.8831 1461 SPBio_001600 CN1CCCN=C1COC(=O)C(O)(C2CCCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P23 mock treatment 262402.0 -1650.0 -0.03 226727.0 -25300.0 -0.53 -0.3966 -0.7504 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2162 P24 mock treatment 237115.0 -26900.0 -0.55 225675.0 -26400.0 -0.55 -0.7746 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A01 mock treatment 253589.0 -14500.0 -0.29 213717.0 -47900.0 -1.0 -0.9129 -0.8781 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A02 mock treatment 256190.0 -11900.0 -0.24 218579.0 -43000.0 -0.9 -0.804 -0.8665 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A03 compound treatment 245648.0 -22400.0 -0.45 264723.0 3140.0 0.07 -0.2753 -0.5994 3045683 SPBio_001601 C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A04 compound treatment 247014.0 -21100.0 -0.43 237728.0 -23900.0 -0.5 -0.6534 -0.9971 3177591 SPBio_001602 COc1cc(cc(OC)c1OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](OC(=O)C)c4cc5OCOc5cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A05 compound treatment 118232.0 -150000.0 -3.04 153683.0 -108000.0 -2.25 -3.7376 -0.989 1465 SPBio_001603 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A06 compound treatment 284886.0 16800.0 0.34 283241.0 21700.0 0.45 0.56 0.9904 2475 SPBio_001604 CC(=CC1C(C(=O)O)C1(C)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A07 compound treatment 249592.0 -18500.0 -0.37 229738.0 -31800.0 -0.66 -0.7341 -0.9634 1489 SPBio_001605 CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A08 compound treatment 238103.0 -30000.0 -0.61 210355.0 -51200.0 -1.07 -1.1844 -0.9643 1013144 SPBio_001606 O=C1OC(=O)C2C3CCC(O3)C21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A09 compound treatment 241934.0 -26100.0 -0.53 239066.0 -22500.0 -0.47 -0.7065 -0.9982 1459 SPBio_001607 OC1CCN(CCCN2c3ccccc3Sc4ccc(C#N)cc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A10 compound treatment 292266.0 24200.0 0.49 284749.0 23200.0 0.48 0.688 1.0 3059791 SPBio_001608 Nc1nc(cs1)/C(=C/CC(=O)O)/C(=O)N[C@H]2[C@H]3SCC=C(N3C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A11 compound treatment 278981.0 10900.0 0.22 274612.0 13000.0 0.27 0.3482 0.9948 1495 SPBio_001609 OC(=O)CCCCC1CCSS1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A12 compound treatment 2829.0 -265000.0 -5.38 2605.0 -259000.0 -5.4 -7.6174 -1.0 3059465 SPBio_001610 Nc1nc(cs1)/C(=N/O)/C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)C=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A13 compound treatment 158547.0 -110000.0 -2.22 137092.0 -124000.0 -2.59 -3.4041 -0.997 1317 SPBio_001611 Fc1ccc(cc1)C(c2ccccc2)(c3ccccc3F)n4ccnc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A14 compound treatment 220876.0 -47200.0 -0.96 220609.0 -41000.0 -0.85 -1.2803 -0.9984 3480112 SPBio_001612 CC(C)CC(N(C)C)C1(CCC1)c2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A15 compound treatment 229282.0 -38800.0 -0.79 241541.0 -20000.0 -0.42 -0.8514 -0.9561 1605 SPBio_001613 OC(Cn1cncn1)(Cn2cncn2)c3ccc(F)cc3F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A16 compound treatment 245261.0 -22800.0 -0.46 244649.0 -16900.0 -0.35 -0.5766 -0.9911 3079224 SPBio_001614 COC1=C(O)C(=O)c2c(O)c3c(O)c(oc3cc2C1=O)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A17 compound treatment 217717.0 -50400.0 -1.02 236190.0 -25400.0 -0.53 -1.096 -0.9532 839435 SPBio_001615 NCCCCNC(=N)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A18 compound treatment 213364.0 -54700.0 -1.11 239441.0 -22100.0 -0.46 -1.1105 -0.9245 3079225 SPBio_001616 OC(=O)CCC1NCC2CC1CN3CCCCC23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A19 compound treatment 227451.0 -40600.0 -0.82 196344.0 -65200.0 -1.36 -1.5435 -0.9712 3250 SPBio_001617 CCCCCCCCCCCCCCCCCCOCC(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A20 compound treatment 251180.0 -16900.0 -0.34 210746.0 -50800.0 -1.06 -0.9912 -0.8904 1592184 SPBio_001618 O=C1CCCC2C3CC(CN21)[C@@H]4CCCCN4C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A21 compound treatment 247371.0 -20700.0 -0.42 230988.0 -30600.0 -0.64 -0.7476 -0.9794 1537011 SPBio_001619 CN(C)CCC(c1ccc(Br)cc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A22 compound treatment 241057.0 -27000.0 -0.55 221826.0 -39800.0 -0.83 -0.9731 -0.9798 3079226 SPBio_001620 C1CN2Cc3ccccc3N=C2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A23 mock treatment 203663.0 -64400.0 -1.31 209401.0 -52200.0 -1.09 -1.6921 -0.9959 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 A24 mock treatment 201153.0 -66900.0 -1.36 200326.0 -61300.0 -1.28 -1.8618 -0.9995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B01 mock treatment 229825.0 -38300.0 -0.78 263181.0 1590.0 0.03 -0.5249 -0.6762 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B02 mock treatment 259281.0 -8790.0 -0.18 269606.0 8020.0 0.17 -0.008 -0.0326 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B03 compound treatment 296966.0 28900.0 0.59 295680.0 34100.0 0.71 0.9164 0.9954 2060222 SPBio_001621 C/C/1=C\CCC(=O)C2CC(C)(C)C2CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B04 compound treatment 287748.0 19700.0 0.4 272024.0 10400.0 0.22 0.4357 0.9593 2515 SPBio_001622 CCCCCCC(C)OC(=O)COc1cc(Cl)c(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B05 compound treatment 123753.0 -144000.0 -2.93 132400.0 -129000.0 -2.69 -3.972 -0.9991 1099943 SPBio_001623 COc1c2C=CC(C)(C)Oc2c(CC=C(C)C)c3oc(=O)c(c(O)c13)c4ccc(O)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B06 compound treatment 288790.0 20700.0 0.42 269387.0 7800.0 0.16 0.4118 0.9146 2517 SPBio_001624 CC(C)N(C(=O)CCl)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B07 compound treatment 294015.0 25900.0 0.53 272889.0 11300.0 0.24 0.5383 0.9343 2060382 SPBio_001625 C/C/1=C\CC(C)(C)\C=C\CC2(C)OC2CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B08 compound treatment 308578.0 40500.0 0.82 283471.0 21900.0 0.46 0.903 0.9615 2518 SPBio_001626 CCCCSP(=O)(SCCCC)SCCCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B09 compound treatment 278281.0 10200.0 0.21 204810.0 -56800.0 -1.18 -0.6901 -0.5747 1981222 SPBio_001627 CCN1CCN(C(=O)NC(C(=O)NC2C3SCC(=C(N3C2=O)C(=O)O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B10 compound treatment 263152.0 -4920.0 -0.1 256085.0 -5500.0 -0.11 -0.1516 -0.9976 2519 SPBio_001628 CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B11 compound treatment 260792.0 -7280.0 -0.15 290002.0 28400.0 0.59 0.3142 0.5149 3174236 SPBio_001629 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c4c(=O)c(O)cc(cc34)[C@H]5Oc6cc(O)cc(O)c6C[C@H]5O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B12 compound treatment 231561.0 -36500.0 -0.74 213462.0 -48100.0 -1.0 -1.2324 -0.9889 2479 SPBio_001630 CCOP(=S)(OCC)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B13 compound treatment 244347.0 -23700.0 -0.48 229258.0 -32300.0 -0.67 -0.8164 -0.9864 2060221 SPBio_001631 COc1ccc(cc1)[C@H]2Oc3cc(OC)cc(OC)c3C[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B14 compound treatment 263413.0 -4660.0 -0.09 255963.0 -5620.0 -0.12 -0.1497 -0.9943 2480 SPBio_001632 COP(=S)(OC)SCn1nnc2ccccc2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B15 compound treatment 269390.0 1310.0 0.03 251920.0 -9670.0 -0.2 -0.1236 -0.6083 2060258 SPBio_001633 CC(=O)O[C@H]1Cc2c(OC(=O)C)cc(OC(=O)C)cc2O[C@@H]1c3ccc(OC(=O)C)c(OC(=O)C)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B16 compound treatment 250183.0 -17900.0 -0.36 255326.0 -6260.0 -0.13 -0.3487 -0.9047 2513 SPBio_001634 OC(=O)CNCP(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B17 compound treatment 262208.0 -5870.0 -0.12 266836.0 5250.0 0.11 -0.0068 -0.0421 2060256 SPBio_001635 CC(=CC1C(CO)C1(C)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B18 compound treatment 248521.0 -19600.0 -0.4 234036.0 -27600.0 -0.57 -0.6862 -0.9837 2514 SPBio_001636 CCCCCCC(C)OC(=O)COc1ccc(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B19 compound treatment 244294.0 -23800.0 -0.48 218586.0 -43000.0 -0.9 -0.9744 -0.9578 1952709 SPBio_001637 COc1ccc2c(C)cc(=O)oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B20 compound treatment 197533.0 -70500.0 -1.43 217268.0 -44300.0 -0.92 -1.6641 -0.9776 2478 SPBio_001638 COP(=S)(OC)Oc1ccc(cc1)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B21 compound treatment 225611.0 -42500.0 -0.86 224759.0 -36800.0 -0.77 -1.1513 -0.9984 1000110 SPBio_001639 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B22 compound treatment 232852.0 -35200.0 -0.71 230322.0 -31300.0 -0.65 -0.9655 -0.9989 2512 SPBio_001640 COC(=O)COc1cc(Cl)c(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B23 mock treatment 246773.0 -21300.0 -0.43 228152.0 -33400.0 -0.7 -0.7979 -0.9736 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 B24 mock treatment 236283.0 -31800.0 -0.64 242435.0 -19200.0 -0.4 -0.7379 -0.9734 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C01 mock treatment 255716.0 -12400.0 -0.25 262938.0 1350.0 0.03 -0.1573 -0.6238 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C02 mock treatment 261926.0 -6150.0 -0.12 245081.0 -16500.0 -0.34 -0.3313 -0.9058 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C03 compound treatment 133726.0 -134000.0 -2.72 98632.0 -163000.0 -3.39 -4.3264 -0.994 3172723 SPBio_001641 CC(=O)OC[C@@]1(O)C[C@@]2(C[C@H]1CCC23)CCC4c5ccoc5CC[C@@]43C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C04 compound treatment 111272.0 -157000.0 -3.18 80991.0 -181000.0 -3.76 -4.9082 -0.9965 3198437 SPBio_001642 C[N+](C)(C)CCOP(=O)(O)OP(=O)(O)OC[C@H]1OC([C@H](O)[C@@H]1O)n2ccc(N)nc2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C05 compound treatment 90644.0 -177000.0 -3.6 74811.0 -187000.0 -3.89 -5.2949 -0.9992 1978 SPBio_001643 OC(=O)/C=C/c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C06 compound treatment 197855.0 -70200.0 -1.42 232034.0 -29600.0 -0.62 -1.442 -0.9297 3079227 SPBio_001644 [O-][N+](=O)/N=C/1\NCCN1Cc2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C07 compound treatment 303143.0 35100.0 0.71 264105.0 2520.0 0.05 0.5398 0.7572 2060330 SPBio_001645 OC[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C08 compound treatment 317423.0 49300.0 1.0 282502.0 20900.0 0.44 1.0155 0.9306 3079228 SPBio_001646 CCNC(=O)CC[C@H](N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C09 compound treatment 245590.0 -22500.0 -0.46 234654.0 -26900.0 -0.56 -0.7191 -0.9947 2060332 SPBio_001647 OC/C=C/c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C10 compound treatment 232251.0 -35800.0 -0.73 167712.0 -93900.0 -1.96 -1.8964 -0.909 3076175 SPBio_001648 COc1cc(ccc1O)[C@H]2Oc3cc(ccc3O[C@@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C11 compound treatment 261333.0 -6740.0 -0.14 236788.0 -24800.0 -0.52 -0.462 -0.8644 907149 SPBio_001649 CN(C)c1nc(N)c(nc1Cl)C(=O)NC(=N)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C12 compound treatment 221732.0 -46300.0 -0.94 240745.0 -20800.0 -0.43 -0.9714 -0.9385 3198531 SPBio_001650 COc1ccc(cc1)c2oc3c(CC=C(C)C)c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(O)c3c(=O)c2O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C13 compound treatment 296613.0 28500.0 0.58 238505.0 -23100.0 -0.48 0.069 0.0918 1316 SPBio_001651 CC(C)(C)NCC(O)c1ccccc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C14 compound treatment 304761.0 36700.0 0.74 229631.0 -32000.0 -0.67 0.0551 0.0552 1672 SPBio_001652 OC(=O)CCc1nc(c(o1)c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C15 compound treatment 236035.0 -32000.0 -0.65 214809.0 -46800.0 -0.97 -1.1484 -0.9806 2060337 SPBio_001653 COc1ccc(cc1O)c2oc3cc(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c(O)c3c(=O)c2OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C16 compound treatment 248830.0 -19200.0 -0.39 250425.0 -11200.0 -0.23 -0.4403 -0.9694 1045397 SPBio_001654 COc1ccc(cc1OC)c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C17 compound treatment 232846.0 -35200.0 -0.71 196724.0 -64900.0 -1.35 -1.4605 -0.9556 2060338 SPBio_001655 CC(C)c1ccc2c(CC[C@H]3C4=C(CC[C@@]32C)C(=O)OC4)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C18 compound treatment 286517.0 18400.0 0.37 246361.0 -15200.0 -0.32 0.04 0.0817 1034727 SPBio_001656 COc1ccc(cc1)c2cc(=O)c3c(OC)c(OC)c(OC)c(OC)c3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C19 compound treatment 267380.0 -696.0 -0.01 260958.0 -630.0 -0.01 -0.0193 -0.9993 2060340 SPBio_001657 CC(=O)/C(=C\c1ccccc1)/CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C20 compound treatment 235218.0 -32900.0 -0.67 233833.0 -27800.0 -0.58 -0.8799 -0.9975 351 SPBio_001658 CC(C)NCC(O)COc1cccc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C21 compound treatment 7826.0 -260000.0 -5.28 4220.0 -257000.0 -5.36 -7.522 -1.0 1020994 SPBio_001659 COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CC=C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C22 compound treatment 279276.0 11200.0 0.23 226836.0 -34800.0 -0.72 -0.3514 -0.4631 2660 SPBio_001660 CCN(C(=O)/C=C/C)c1ccccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C23 mock treatment 286240.0 18200.0 0.37 244219.0 -17400.0 -0.36 0.0045 0.0088 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 C24 mock treatment 235124.0 -33000.0 -0.67 210203.0 -51400.0 -1.07 -1.2293 -0.9742 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D01 mock treatment 262441.0 -5630.0 -0.11 262779.0 1190.0 0.02 -0.0632 -0.5409 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D02 mock treatment 275373.0 7300.0 0.15 276229.0 14600.0 0.31 0.3203 0.9448 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D03 compound treatment 295547.0 27500.0 0.56 244935.0 -16700.0 -0.35 0.1485 0.2263 2060195 SPBio_001661 CC1(C)CC23C1CCC3(C)C(O)CCC2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D04 compound treatment 285881.0 17800.0 0.36 273153.0 11600.0 0.24 0.4256 0.9807 2510 SPBio_001662 COC(=O)COc1ccc(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D05 compound treatment 289569.0 21500.0 0.44 289680.0 28100.0 0.59 0.7219 0.9894 2060197 SPBio_001663 COC1(C)CCC2OC2(C)CCC3C1CC3(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D06 compound treatment 291810.0 23700.0 0.48 274941.0 13400.0 0.28 0.5369 0.9661 2511 SPBio_001664 COC(=O)CCCOc1ccc(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D07 compound treatment 284506.0 16400.0 0.33 274935.0 13300.0 0.28 0.4321 0.996 2069257 SPBio_001665 CC1(C)CC2C1CCC(=C)C(O)CCC2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D08 compound treatment 268587.0 511.0 0.01 259338.0 -2250.0 -0.05 -0.0258 -0.5378 2509 SPBio_001666 CCc1cccc(CC)c1N(COC)C(=O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D09 compound treatment 265459.0 -2620.0 -0.05 274132.0 12500.0 0.26 0.1473 0.5523 2060199 SPBio_001667 CC1(C)CC2C1CCC3(C)OC2(C)CCC3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D10 compound treatment 286381.0 18300.0 0.37 283795.0 22200.0 0.46 0.5895 0.994 2507 SPBio_001668 OC(=O)CCCOc1ccc(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D11 compound treatment 284478.0 16400.0 0.33 244880.0 -16700.0 -0.35 -0.011 -0.0228 2060200 SPBio_001669 CC12CCC3C(CC3(C)C)C(C)(O)CCC2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D12 compound treatment 267755.0 -321.0 -0.01 273198.0 11600.0 0.24 0.1664 0.6878 2506 SPBio_001670 OC(=O)COc1ccc(Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D13 compound treatment 271033.0 2960.0 0.06 271062.0 9470.0 0.2 0.182 0.8821 2060202 SPBio_001671 CC1(C)CC2C1CCC3(C)OC2(C)CCC3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D14 compound treatment 261976.0 -6100.0 -0.12 273687.0 12100.0 0.25 0.0908 0.3234 2481 SPBio_001672 CCOP(=S)(OCC)SCCSCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D15 compound treatment 223829.0 -44200.0 -0.9 245349.0 -16200.0 -0.34 -0.8735 -0.9111 2060204 SPBio_001673 CC(=O)OC1CC(C)(C)C2CCC3(C)CC12CCC3OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D16 compound treatment 261193.0 -6880.0 -0.14 239402.0 -22200.0 -0.46 -0.4255 -0.8813 2482 SPBio_001674 CCOC(=O)/C=C(\C)/OP(=O)(OC)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D17 compound treatment 298763.0 30700.0 0.62 281663.0 20100.0 0.42 0.7356 0.9813 2060219 SPBio_001675 CC(=O)OC/1CCC(=C)[C@H]2CC(C)(C)[C@@H]2C\C=C1/C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D18 compound treatment 249633.0 -18400.0 -0.37 236213.0 -25400.0 -0.53 -0.6382 -0.9856 2483 SPBio_001676 COP(=O)(OC)OC(Br)C(Cl)(Cl)Br 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D19 compound treatment 261448.0 -6630.0 -0.13 234993.0 -26600.0 -0.55 -0.4868 -0.8538 2060264 SPBio_001677 C[C@@H]1CC[C@]2(CCC3(C)[C@]4(OC2=O)C=CC5[C@@]6(C)CC[C@H](O)C(C)(C)C6CC[C@]53C)C4[C@H]1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D20 compound treatment 255157.0 -12900.0 -0.26 235890.0 -25700.0 -0.54 -0.5637 -0.9459 2485 SPBio_001678 CCS(=O)CCSP(=O)(OC)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D21 compound treatment 180986.0 -87100.0 -1.77 19612.0 -242000.0 -5.04 -4.813 -0.9011 2060266 SPBio_001679 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC(=O)C4[C@@]5(C)CC[C@H](OC(=O)C)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D22 compound treatment 270296.0 2220.0 0.05 230861.0 -30700.0 -0.64 -0.4208 -0.6558 2490 SPBio_001680 CCOP(=S)(OCC)SCSCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D23 mock treatment 249055.0 -19000.0 -0.39 250395.0 -11200.0 -0.23 -0.4375 -0.971 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 D24 mock treatment 226332.0 -41700.0 -0.85 211322.0 -50300.0 -1.05 -1.3389 -0.9944 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E01 mock treatment 246149.0 -21900.0 -0.44 278169.0 16600.0 0.35 -0.0701 -0.1245 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E02 mock treatment 312354.0 44300.0 0.9 253971.0 -7620.0 -0.16 0.5225 0.5732 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E03 compound treatment 260688.0 -7390.0 -0.15 245954.0 -15600.0 -0.33 -0.3362 -0.9379 3172852 SPBio_001681 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E04 compound treatment 299866.0 31800.0 0.64 278017.0 16400.0 0.34 0.6977 0.9562 3079229 SPBio_001682 CC1(C)C2CC(O)C(C)(O)CC21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E05 compound treatment 265673.0 -2400.0 -0.05 264817.0 3230.0 0.07 0.0131 0.158 3172853 SPBio_001683 C[C@@H]1OC(O[C@@H]2[C@@H](O)[C@@H](O)COC2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E06 compound treatment 290872.0 22800.0 0.46 285331.0 23700.0 0.49 0.6766 0.9994 1053060 SPBio_001684 COc1ccc(cc1OC)c2oc3ccccc3c(=O)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E07 compound treatment 297000.0 28900.0 0.59 270502.0 8910.0 0.19 0.5459 0.8876 2060345 SPBio_001685 C[C@@H]1OC(O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](OC9OC[C@H](O)[C@H](O)[C@H]9OC%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)[C@@](C)(CO)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E08 compound treatment 260698.0 -7380.0 -0.15 277280.0 15700.0 0.33 0.1254 0.3488 1864491 SPBio_001686 COc1ccc(cc1)c2coc3cc(OC)cc(OC)c3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E09 compound treatment 208652.0 -59400.0 -1.2 78166.0 -183000.0 -3.82 -3.5539 -0.887 829 SPBio_001687 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E10 compound treatment 290824.0 22700.0 0.46 249621.0 -12000.0 -0.25 0.1498 0.2858 3198532 SPBio_001688 COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E11 compound treatment 274627.0 6550.0 0.13 262270.0 682.0 0.01 0.104 0.7783 1054504 SPBio_001689 COc1c(OCC(O)C(C)(C)O)ccc2c(OC)c3ccoc3nc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E12 compound treatment 285054.0 17000.0 0.34 256761.0 -4830.0 -0.1 0.1723 0.4804 435 SPBio_001690 CC(C)Cn1c(=O)n(C)c(=O)c2nc[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E13 compound treatment 285109.0 17000.0 0.35 251899.0 -9690.0 -0.2 0.1014 0.2536 1024517 SPBio_001691 COc1cc2CCNC(C)c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E14 compound treatment 268806.0 730.0 0.01 272348.0 10800.0 0.22 0.169 0.7522 832325 SPBio_001692 COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E15 compound treatment 260782.0 -7290.0 -0.15 279096.0 17500.0 0.36 0.1534 0.3897 3079221 SPBio_001693 O=c1cccc2C3CC(Cn21)[C@@H]4CCCCN4C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E16 compound treatment 287384.0 19300.0 0.39 252098.0 -9490.0 -0.2 0.137 0.3124 1099044 SPBio_001694 CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n2cncn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E17 compound treatment 295267.0 27200.0 0.55 258239.0 -3350.0 -0.07 0.3405 0.6127 2060358 SPBio_001695 C[C@@H]1CCC2[C@](C)(CO)[C@@H](O)CC[C@]2(C)[C@]31CC[C@@](CO)(CCO)O3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E18 compound treatment 300014.0 31900.0 0.65 269560.0 7970.0 0.17 0.5753 0.8606 3198533 SPBio_001696 CCc1c(C)c2=Cc3c(C=C)c(C)c4C=c5c(C)c(CCC(=O)O)c6=C7C(C(=O)O)C(=O)c8c(C)c9C=c1n2[Cu](n9c78)(n43)n56 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E19 compound treatment 2785.0 -265000.0 -5.38 3022.0 -259000.0 -5.39 -7.6119 -1.0 2060328 SPBio_001697 CC(C)CC(=O)c1c(O)c(C)c(O)c2c1oc3c(C(=O)CC(C)C)c(O)c(C)c(O)c32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E20 compound treatment 279721.0 11600.0 0.24 257312.0 -4280.0 -0.09 0.1039 0.412 1017318 SPBio_001698 NC(=O)c1ccc(N)nc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E21 compound treatment 288855.0 20800.0 0.42 224138.0 -37400.0 -0.78 -0.2538 -0.2863 2060307 SPBio_001699 COc1ccc2[C@@H](O)[C@H](Cc3ccc(OC)c(OC)c3)COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E22 compound treatment 265779.0 -2300.0 -0.05 280478.0 18900.0 0.39 0.2453 0.6191 2109 SPBio_001700 OCc1c[nH]c2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E23 mock treatment 234953.0 -33100.0 -0.67 246995.0 -14600.0 -0.3 -0.6898 -0.9358 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 E24 mock treatment 251453.0 -16600.0 -0.34 242373.0 -19200.0 -0.4 -0.5213 -0.9963 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F01 mock treatment 278401.0 10300.0 0.21 300607.0 39000.0 0.81 0.7228 0.8611 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F02 mock treatment 284400.0 16300.0 0.33 293988.0 32400.0 0.67 0.7113 0.9462 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F03 compound treatment 290857.0 22800.0 0.46 303533.0 41900.0 0.87 0.9445 0.9556 2060268 SPBio_001701 C[C@@H]1CC[C@]2(CCC3(C)[C@]4(OC2=O)C=CC5[C@@]6(C)CCC(=O)C(C)(C)C6CC[C@]53C)C4[C@H]1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F04 compound treatment 320082.0 52000.0 1.05 333994.0 72400.0 1.51 1.8121 0.9847 2486 SPBio_001702 CNC(=O)CSP(=S)(OC)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F05 compound treatment 320431.0 52400.0 1.06 321175.0 59600.0 1.24 1.6283 0.997 2060270 SPBio_001703 CC(C)c1ccc2c(CCC3C(C)(CCCC32C)C(=O)N)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F06 compound treatment 251895.0 -16200.0 -0.33 263040.0 1450.0 0.03 -0.2106 -0.6392 2488 SPBio_001704 CCOP(=S)(OCC)SCn1c(=O)oc2cc(Cl)ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F07 compound treatment 318592.0 50500.0 1.02 305875.0 44300.0 0.92 1.3766 0.9986 2060272 SPBio_001705 CC1CCC2C(CC2(C)C)C(=C)CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F08 compound treatment 290122.0 22000.0 0.45 298848.0 37300.0 0.78 0.8649 0.9656 2489 SPBio_001706 COP(=O)(N)SC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F09 compound treatment 292599.0 24500.0 0.5 318090.0 56500.0 1.18 1.1839 0.9265 2060274 SPBio_001707 CC(C)C1CC=C(C)C2CC(=O)C(=CC12)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F10 compound treatment 296077.0 28000.0 0.57 284831.0 23200.0 0.48 0.7438 0.9969 3046265 SPBio_001708 Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F11 compound treatment 280914.0 12800.0 0.26 278549.0 17000.0 0.35 0.4339 0.9887 3053888 SPBio_001709 CC(=CCC[C@](C)(OC(=O)C)C1CCC(=CC1)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F12 compound treatment 272342.0 4270.0 0.09 277931.0 16300.0 0.34 0.3019 0.8594 2534 SPBio_001710 ClC(=C(c1ccc(Cl)cc1)c2ccc(Cl)cc2)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F13 compound treatment 314112.0 46000.0 0.93 303230.0 41600.0 0.87 1.2734 0.9993 3053889 SPBio_001711 C[C@@H]1CC[C@H]2C(C)(C)C3CC12CC[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F14 compound treatment 220686.0 -47400.0 -0.96 262805.0 1220.0 0.03 -0.6614 -0.6882 1304 SPBio_001712 ClC1=C(Cl)C2(Cl)C3C4CC(C5OC54)C3C1(Cl)C2(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F15 compound treatment 267637.0 -439.0 -0.01 276323.0 14700.0 0.31 0.2108 0.6863 2069281 SPBio_001713 C[C@@]12CCC3C(CCc4cc(OC(=O)c5ccccc5)ccc34)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F16 compound treatment 102137.0 -166000.0 -3.36 74469.0 -187000.0 -3.9 -5.1352 -0.9973 2535 SPBio_001714 CC1(C)C(C(Cl)Cl)C2(Cl)C(Cl)C(Cl)C1(Cl)C2(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F17 compound treatment 297779.0 29700.0 0.6 288690.0 27100.0 0.56 0.825 0.9995 3053891 SPBio_001715 OC(=O)C/C(=C\C(=O)O)/C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F18 compound treatment 297455.0 29400.0 0.6 263241.0 1650.0 0.03 0.4455 0.7467 2536 SPBio_001716 ClC1CC2C(C1Cl)C3(Cl)C(Cl)C(Cl)C2(Cl)C3(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F19 compound treatment 296642.0 28600.0 0.58 277402.0 15800.0 0.33 0.6425 0.9643 1045072 SPBio_001717 NC(CSCSCC(N)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F20 compound treatment 304975.0 36900.0 0.75 267422.0 5830.0 0.12 0.6149 0.8114 2520 SPBio_001718 Clc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F21 compound treatment 296438.0 28400.0 0.57 256419.0 -5170.0 -0.11 0.3304 0.5649 3054971 SPBio_001719 O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F22 compound treatment 8450.0 -260000.0 -5.26 6207.0 -255000.0 -5.32 -7.4838 -1.0 2521 SPBio_001720 Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F23 mock treatment 242671.0 -25400.0 -0.52 268850.0 7260.0 0.15 -0.2572 -0.4791 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 F24 mock treatment 250134.0 -17900.0 -0.36 260805.0 -783.0 -0.02 -0.2687 -0.7381 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G01 mock treatment 265028.0 -3050.0 -0.06 276461.0 14900.0 0.31 0.1754 0.5552 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G02 mock treatment 295339.0 27300.0 0.55 261593.0 5.19 0.0 0.3909 0.7072 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G03 compound treatment 235823.0 -32300.0 -0.65 260812.0 -776.0 -0.02 -0.4738 -0.7244 3079222 SPBio_001721 CC(=O)OC[C@H]1O[C@@H](Oc2cc(OC(=O)C)c3c(=O)cc(oc3c2)c4ccc(OC(=O)C)cc4)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G04 compound treatment 268989.0 913.0 0.02 305960.0 44400.0 0.92 0.6667 0.7211 122 SPBio_001722 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G05 compound treatment 182268.0 -85800.0 -1.74 190612.0 -71000.0 -1.48 -2.2756 -0.9967 2060255 SPBio_001723 CC(=O)Oc1ccc(/C=C/c2cc(OC(=O)C)cc(OC(=O)C)c2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G06 compound treatment 277431.0 9360.0 0.19 291494.0 29900.0 0.62 0.5747 0.8824 1788 SPBio_001724 NC(=O)CS(=O)C(c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G07 compound treatment 298935.0 30900.0 0.63 277156.0 15600.0 0.32 0.6717 0.9532 3054095 SPBio_001725 CCC(/C=C/[C@@H](C)[C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G08 compound treatment 300906.0 32800.0 0.67 277225.0 15600.0 0.33 0.701 0.946 3304 SPBio_001726 Fc1ccc(cc1)C(=O)C2CCN(CCn3c(=O)[nH]c4ccccc4c3=O)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G09 compound treatment 293091.0 25000.0 0.51 262322.0 734.0 0.02 0.3694 0.7281 3174115 SPBio_001727 CC[C@H](CCC(C)[C@H]1CCC2C3CCC4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G10 compound treatment 164416.0 -104000.0 -2.1 209559.0 -52000.0 -1.08 -2.2524 -0.9526 3055363 SPBio_001728 COc1cc(/C=C/C(=C/C(=O)\C=C\c2ccc(O)c(OC)c2)/O)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G11 compound treatment 246771.0 -21300.0 -0.43 270150.0 8560.0 0.18 -0.1793 -0.3836 2060290 SPBio_001729 C[C@@H]1OC(O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(C(O)C[C@]54C)C(=O)O[C@@H]7OC[C@H](O)[C@@H](O)[C@H]7OC8O[C@@H](C)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H]8O)C2(C)C)[C@H](O)[C@H](O)[C@H]1O[C@@H]%10OC[C@@H](O)[C@H](O)[C@H]%10O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G12 compound treatment 270460.0 2380.0 0.05 242267.0 -19300.0 -0.4 -0.2504 -0.6178 1912 SPBio_001730 [O-][N+](=O)c1cccc2cn[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G13 compound treatment 303798.0 35700.0 0.72 253594.0 -7990.0 -0.17 0.3943 0.5307 3055472 SPBio_001731 CC(C)CCCC(C)[C@H]1CCC2C3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G14 compound treatment 315443.0 47400.0 0.96 275475.0 13900.0 0.29 0.8836 0.881 1003535 SPBio_001732 ONC(=O)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G15 compound treatment 266656.0 -1420.0 -0.03 271653.0 10100.0 0.21 0.1279 0.6044 3055308 SPBio_001733 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)C[C@@H]31 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G16 compound treatment 280259.0 12200.0 0.25 230973.0 -30600.0 -0.64 -0.2763 -0.404 2060198 SPBio_001734 COc1ccc2C=C3c4cc(OC)c(OC)cc4OCC3(O)Oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G17 compound treatment 233436.0 -34600.0 -0.7 216360.0 -45200.0 -0.94 -1.1628 -0.9895 2060301 SPBio_001735 COc1ccc(cc1O)c2cc(=O)c3c(O)cc(O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G18 compound treatment 18071.0 -250000.0 -5.07 140628.0 -121000.0 -2.52 -5.3657 -0.948 3198534 SPBio_001736 OCC(O)CC(O)CCCCCCCCCCCC=C.OCC(O)CC(O)CCCCCCCCCCCC#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G19 compound treatment 220587.0 -47500.0 -0.96 226831.0 -34800.0 -0.72 -1.1928 -0.9901 1119359 SPBio_001737 COc1cc2ccc(=O)oc2c(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G20 compound treatment 256145.0 -11900.0 -0.24 231044.0 -30500.0 -0.64 -0.621 -0.9122 3198535 SPBio_001738 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C[C@H](O)[C@]2(C)C3CC[C@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G21 compound treatment 266995.0 -1080.0 -0.02 283624.0 22000.0 0.46 0.3091 0.6726 3055306 SPBio_001739 C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@H]1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G22 compound treatment 239036.0 -29000.0 -0.59 246484.0 -15100.0 -0.31 -0.6388 -0.9569 734 SPBio_001740 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G23 mock treatment 284697.0 16600.0 0.34 265979.0 4390.0 0.09 0.303 0.8677 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 G24 mock treatment 289661.0 21600.0 0.44 269856.0 8270.0 0.17 0.4312 0.917 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H01 mock treatment 284721.0 16600.0 0.34 279416.0 17800.0 0.37 0.5012 0.9989 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H02 mock treatment 297603.0 29500.0 0.6 271587.0 10000.0 0.21 0.5706 0.9002 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H03 compound treatment 312119.0 44000.0 0.89 297613.0 36000.0 0.75 1.1621 0.9963 1007364 SPBio_001741 CCOC(=O)C1C(C=C(C)C)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H04 compound treatment 287554.0 19500.0 0.39 313222.0 51600.0 1.08 1.0399 0.9075 2522 SPBio_001742 CNC(=O)Oc1cccc2CC(C)(C)Oc21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H05 compound treatment 343934.0 75900.0 1.54 294077.0 32500.0 0.68 1.566 0.932 852250 SPBio_001743 C1CCC(NC1)c2cccnc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H06 compound treatment 310616.0 42500.0 0.86 318451.0 56900.0 1.18 1.4475 0.9878 3172728 SPBio_001744 CNC(=O)O/N=C(/C)\SC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H07 compound treatment 312071.0 44000.0 0.89 289990.0 28400.0 0.59 1.0491 0.9801 1610 SPBio_001745 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H08 compound treatment 329353.0 61300.0 1.24 286740.0 25200.0 0.52 1.2489 0.9263 2527 SPBio_001746 COP(=S)(OC)Oc1ccc(Sc2ccc(OP(=S)(OC)OC)cc2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H09 compound treatment 279445.0 11400.0 0.23 286530.0 24900.0 0.52 0.5304 0.9331 1014978 SPBio_001747 OCC(O)C(O)C(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H10 compound treatment 358409.0 90300.0 1.83 282961.0 21400.0 0.45 1.6098 0.8541 2530 SPBio_001748 CCCSP(=O)(OCC)SCCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H11 compound treatment 293868.0 25800.0 0.52 264162.0 2570.0 0.05 0.4077 0.7756 1003823 SPBio_001749 Cc1occc(=O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H12 compound treatment 315814.0 47700.0 0.97 298369.0 36800.0 0.77 1.2262 0.9933 2532 SPBio_001750 CC(C)(C)c1ccc(OC2CCCCC2OS(=O)OCC#C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H13 compound treatment 326123.0 58000.0 1.18 302449.0 40900.0 0.85 1.434 0.9874 1052459 SPBio_001751 COc1c2ccoc2cc3oc(C)cc(=O)c13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H14 compound treatment 300534.0 32500.0 0.66 290720.0 29100.0 0.61 0.8944 0.9992 2491 SPBio_001752 COC(=O)c1c(Cl)c(Cl)c(C(=O)OC)c(Cl)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H15 compound treatment 262904.0 -5170.0 -0.1 299391.0 37800.0 0.79 0.4827 0.6076 2069297 SPBio_001753 CC(C)CCCC(C)[C@H]1CCC2C3CC=C4C[C@H](CC[C@]4(C)C3CC[C@]12C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H16 compound treatment 315430.0 47400.0 0.96 274829.0 13200.0 0.28 0.8739 0.8749 2492 SPBio_001754 CC(C)Nc1nc(Cl)nc(NC(C)C)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H17 compound treatment 331275.0 63200.0 1.28 306636.0 45000.0 0.94 1.5696 0.9883 470 SPBio_001755 OC(=O)CCCc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H18 compound treatment 279791.0 11700.0 0.24 289253.0 27700.0 0.58 0.5755 0.9232 2493 SPBio_001756 CCC(=O)Nc1ccc(Cl)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H19 compound treatment 268676.0 600.0 0.01 290745.0 29200.0 0.61 0.4381 0.7211 1000133 SPBio_001757 C[C@@]12CCC3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H20 compound treatment 291685.0 23600.0 0.48 253861.0 -7730.0 -0.16 0.2246 0.4448 2494 SPBio_001758 CCNc1nc(Cl)nc(NCC)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H21 compound treatment 240052.0 -28000.0 -0.57 276216.0 14600.0 0.3 -0.1862 -0.2889 2060499 SPBio_001759 OC[C@H]1O[C@@H](Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)[C@H](O[C@@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H22 compound treatment 259020.0 -9060.0 -0.18 278292.0 16700.0 0.35 0.1163 0.2955 2495 SPBio_001760 CCNc1nc(Cl)nc(NC(C)C)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H23 mock treatment 270028.0 1950.0 0.04 246251.0 -15300.0 -0.32 -0.1979 -0.6148 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 H24 mock treatment 280457.0 12400.0 0.25 218732.0 -42900.0 -0.89 -0.4538 -0.4893 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I01 mock treatment 253599.0 -14500.0 -0.29 258095.0 -3490.0 -0.07 -0.259 -0.8565 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I02 mock treatment 300759.0 32700.0 0.66 247881.0 -13700.0 -0.29 0.2666 0.3695 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I03 compound treatment 268094.0 18.3 0.0 271956.0 10400.0 0.22 0.153 0.7083 2060321 SPBio_001761 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4c(=O)cc(oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I04 compound treatment 265933.0 -2140.0 -0.04 267983.0 6400.0 0.13 0.0635 0.4531 2060201 SPBio_001762 CC(=O)OCC(O)CC(O)CCCCCCCCCCCC#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I05 compound treatment 227760.0 -40300.0 -0.82 246036.0 -15600.0 -0.32 -0.807 -0.9179 3173485 SPBio_001763 OC[C@H]1O[C@H](Oc2cccc3[C@H]([C@@H]4c5cccc(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(=O)O)c8cc(cc(O)c8C(=O)c23)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I06 compound treatment 268517.0 441.0 0.01 304776.0 43200.0 0.9 0.6425 0.7141 2069229 SPBio_001764 Oc1ccc2oc3ccccc3c(=O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I07 compound treatment 284246.0 16200.0 0.33 268114.0 6530.0 0.14 0.3279 0.9241 2060342 SPBio_001765 O[C@@H]1[C@H](Oc2cc(O)ccc2C1=O)c3cc(O)c(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I08 compound treatment 299864.0 31800.0 0.64 289474.0 27900.0 0.58 0.8665 0.9987 2060279 SPBio_001766 CC(=O)OC1CC[C@@]2(C)C(CC[C@]3(C)C2CCC4C5CC(C)(C)CCC5(CC[C@]43C)C(=O)O)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I09 compound treatment 269221.0 1150.0 0.02 263100.0 1510.0 0.03 0.0387 0.9887 2060442 SPBio_001767 CCC(N)C(O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I10 compound treatment 311705.0 43600.0 0.88 268758.0 7170.0 0.15 0.7311 0.815 2069285 SPBio_001768 CCCCCC(=O)Cc1cc(O)cc(O)c1C(=O)Oc2cc(CC(=O)CCCCC)c(C(=O)O)c(OC)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I11 compound treatment 312475.0 44400.0 0.9 285649.0 24100.0 0.5 0.9909 0.9618 2060343 SPBio_001769 CCCc1occc(=O)c1/C=C/O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I12 compound treatment 2478.0 -266000.0 -5.38 3019.0 -259000.0 -5.39 -7.6164 -1.0 2524 SPBio_001770 COP(=O)(NC(=O)C)SC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I13 compound treatment 296324.0 28200.0 0.57 273082.0 11500.0 0.24 0.5743 0.9252 2060303 SPBio_001771 Cc1occc(=O)c1/C=C/O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I14 compound treatment 349066.0 81000.0 1.64 296174.0 34600.0 0.72 1.6705 0.9317 2528 SPBio_001772 CNC(=O)Oc1cccc2OC(C)(C)Oc21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I15 compound treatment 223419.0 -44700.0 -0.91 170601.0 -91000.0 -1.9 -1.9805 -0.9428 1000697 SPBio_001773 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(O[C@@H]4O[C@@H]5CO[C@H](OC5[C@H](O)[C@H]4O)c6cccs6)c7cc8OCOc8cc27 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I16 compound treatment 301822.0 33700.0 0.68 297037.0 35400.0 0.74 1.006 0.9993 2060192 SPBio_001774 CC1(C)CC2C1CCC3(C)CCCC2(O)C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I17 compound treatment 314278.0 46200.0 0.94 308967.0 47400.0 0.99 1.3603 0.9997 1835 SPBio_001775 CCCc1nn(C)c2c(=O)[nH]c(nc12)c3cc(ccc3OCC)S(=O)(=O)N4CCN(C)CC4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I18 compound treatment 290787.0 22700.0 0.46 300305.0 38700.0 0.81 0.8959 0.9646 3079231 SPBio_001776 CC1(C)O[C@H]2CC(=O)OC[C@@]23[C@H]1CC(=O)[C@]4(C)[C@@H]3CC[C@@]5(C)[C@@H](OC(=O)[C@H]6O[C@]654)c7ccoc7 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I19 compound treatment 2676.0 -265000.0 -5.38 2627.0 -259000.0 -5.39 -7.6193 -1.0 2060453 SPBio_001777 Clc1c(Cl)c(C#N)c(Cl)c(C#N)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I20 compound treatment 269703.0 1630.0 0.03 268280.0 6690.0 0.14 0.1219 0.8509 1393 SPBio_001778 CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I21 compound treatment 306835.0 38800.0 0.79 290747.0 29200.0 0.61 0.9852 0.9919 2060298 SPBio_001779 CCCCCC1C(CC(=O)O)CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I22 compound treatment 278646.0 10600.0 0.21 300815.0 39200.0 0.82 0.7294 0.8633 3055569 SPBio_001780 OCc1cccnc1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I23 mock treatment 259123.0 -8950.0 -0.18 271186.0 9600.0 0.2 0.0131 0.0483 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 I24 mock treatment 260415.0 -7660.0 -0.16 243522.0 -18100.0 -0.38 -0.3759 -0.9234 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J01 mock treatment 326021.0 57900.0 1.17 293479.0 31900.0 0.66 1.3004 0.9636 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J02 mock treatment 292772.0 24700.0 0.5 294632.0 33000.0 0.69 0.8408 0.9878 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J03 compound treatment 345455.0 77400.0 1.57 278173.0 16600.0 0.35 1.3536 0.8427 2060362 SPBio_001781 COc1ccc(cc1)c2c(OC)c3c(OC)c4C=CC(C)(C)Oc4cc3oc2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J04 compound treatment 336214.0 68100.0 1.38 296660.0 35100.0 0.73 1.4934 0.9557 2497 SPBio_001782 CNC(=O)N(C)c1nnc(s1)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J05 compound treatment 281135.0 13100.0 0.26 292292.0 30700.0 0.64 0.6395 0.9238 2060104 SPBio_001783 COc1cc(C)c2c(=O)c3c(O)cc(O)cc3oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J06 compound treatment 337247.0 69200.0 1.4 304918.0 43300.0 0.9 1.6299 0.9773 2498 SPBio_001784 COc1c(Cl)ccc(Cl)c1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J07 compound treatment 316173.0 48100.0 0.98 309139.0 47600.0 0.99 1.39 1.0 1029490 SPBio_001785 COc1cc(O)c(C)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J08 compound treatment 318963.0 50900.0 1.03 297385.0 35800.0 0.75 1.2568 0.9873 2499 SPBio_001786 CCCCN(CC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J09 compound treatment 304957.0 36900.0 0.75 270412.0 8820.0 0.18 0.6587 0.8555 1060118 SPBio_001787 COc1cc(OC)c2c(=O)c(OC)c(oc2c1)c3ccc(OC)c(OC)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J10 compound treatment 352002.0 83900.0 1.7 302450.0 40900.0 0.85 1.805 0.9488 2500 SPBio_001788 COc1nc(NC(C)C)nc(NC(C)C)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J11 compound treatment 291047.0 23000.0 0.47 283803.0 22200.0 0.46 0.6565 1.0 2542 SPBio_001789 CCCCOC(=O)c1ccccc1C(=O)OCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J12 compound treatment 312576.0 44500.0 0.9 290102.0 28500.0 0.59 1.058 0.9794 2501 SPBio_001790 CCc1cccc(C)c1N(C(C)COC)C(=O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J13 compound treatment 2302.0 -266000.0 -5.39 2307.0 -259000.0 -5.4 -7.6294 -1.0 2060080 SPBio_001791 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CC6CC4C(=O)c3c(O)c2C=C1)C(C/C=C(/C)\C(=O)O)(OC5(C)C)C6O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J14 compound treatment 322735.0 54700.0 1.11 306377.0 44800.0 0.93 1.4433 0.9963 2502 SPBio_001792 Clc1cccc(Cl)c1C#N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J15 compound treatment 323339.0 55300.0 1.12 292416.0 30800.0 0.64 1.2463 0.9651 1471 SPBio_001793 CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J16 compound treatment 301929.0 33900.0 0.69 278714.0 17100.0 0.36 0.7376 0.9536 2503 SPBio_001794 CSc1nc(NC(C)C)nc(NC(C)C)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J17 compound treatment 285233.0 17200.0 0.35 293843.0 32300.0 0.67 0.7211 0.953 832 SPBio_001795 CCCn1c(=O)n(CCC)c2[nH]c(nc2c1=O)C3CCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J18 compound treatment 303609.0 35500.0 0.72 309430.0 47800.0 1.0 1.2141 0.9873 2504 SPBio_001796 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J19 compound treatment 271777.0 3700.0 0.08 140035.0 -122000.0 -2.53 -1.7376 -0.6859 3198539 SPBio_001797 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CC6C=C4C(=O)c3c(O)c2C=C1)C(C/C=C(\C)/C(=O)N)(OC5(C)C)C6=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J20 compound treatment 259437.0 -8640.0 -0.18 265093.0 3510.0 0.07 -0.0722 -0.3805 2505 SPBio_001798 CC(C)N1C(=O)c2ccccc2NS1(=O)=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J21 compound treatment 289646.0 21600.0 0.44 252768.0 -8820.0 -0.18 0.1793 0.378 2069318 SPBio_001799 C[C@@H](NC(=O)/C(=C\c1ccc(O)c(O)c1)/C#N)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J22 compound treatment 257282.0 -10800.0 -0.22 233391.0 -28200.0 -0.59 -0.5701 -0.9095 2537 SPBio_001800 COc1ccc(cc1)C(c2ccc(OC)cc2)C(Cl)(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J23 mock treatment 275782.0 7710.0 0.16 284243.0 22700.0 0.47 0.4442 0.8935 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 J24 mock treatment 262466.0 -5610.0 -0.11 269149.0 7560.0 0.16 0.031 0.1594 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K01 mock treatment 257225.0 -10900.0 -0.22 279445.0 17900.0 0.37 0.1075 0.2488 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K02 mock treatment 289541.0 21500.0 0.44 288037.0 26400.0 0.55 0.6973 0.9932 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K03 compound treatment 2962.0 -265000.0 -5.37 2642.0 -259000.0 -5.39 -7.615 -1.0 2060271 SPBio_001801 CCC(C)C(=O)c1c(O)c(C)c2oc3c(C)c(O)c(C(=O)C(C)CC)c(O)c3c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K04 compound treatment 214778.0 -53300.0 -1.08 296681.0 35100.0 0.73 -0.2471 -0.1894 1048 SPBio_001802 CCn1cc(C(=O)O)c(=O)c2cc(F)c(nc12)N3CCNCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K05 compound treatment 399430.0 131000.0 2.66 355549.0 94000.0 1.96 3.2671 0.9885 1386109 SPBio_001803 Oc1ccc2c(=O)c(O)c(oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K06 compound treatment 149337.0 -119000.0 -2.41 179585.0 -82000.0 -1.71 -2.9101 -0.9859 709 SPBio_001804 COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K07 compound treatment 326916.0 58800.0 1.19 302629.0 41000.0 0.86 1.4481 0.9867 907120 SPBio_001805 CC(N)C(=O)OC(C)(C)Cc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K08 compound treatment 331257.0 63200.0 1.28 315693.0 54100.0 1.13 1.7027 0.998 744 SPBio_001806 Cn1cnc2[nH]c(=O)n(C)c(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K09 compound treatment 275437.0 7360.0 0.15 231992.0 -29600.0 -0.62 -0.3305 -0.5209 2060459 SPBio_001807 OC[C@H]1OC2[C@@H](Oc3nc(=N)ccn23)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K10 compound treatment 325591.0 57500.0 1.17 299650.0 38100.0 0.79 1.3852 0.9823 1416 SPBio_001808 Cn1c(=O)n(C)c2[nH]c(nc2c1=O)C3CCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K11 compound treatment 2464.0 -266000.0 -5.38 5237.0 -256000.0 -5.34 -7.5839 -1.0 1001314 SPBio_001809 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)[C@@H]4N[C@@H](COCCOC)O[C@H]([C@H]4C)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K12 compound treatment 318737.0 50700.0 1.03 296588.0 35000.0 0.73 1.2418 0.9859 1505 SPBio_001810 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K13 compound treatment 336776.0 68700.0 1.39 305027.0 43400.0 0.9 1.6247 0.9782 3474314 SPBio_001811 CN1CCCCC1C(=O)Nc2c(C)cccc2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K14 compound treatment 299588.0 31500.0 0.64 306200.0 44600.0 0.93 1.1089 0.9833 1587004 SPBio_001812 COc1ccc(cc1)C2Sc3ccccc3N(CCN(C)C)C(=O)C2OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K15 compound treatment 292394.0 24300.0 0.49 301232.0 39600.0 0.83 0.9326 0.9696 2060476 SPBio_001813 C[C@H]1[C@@H]2CCC(=C3[C@@H]([C@H]2OC1=O)C(=CC3=O)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K16 compound treatment 327142.0 59100.0 1.2 328712.0 67100.0 1.4 1.8355 0.997 4362 SPBio_001814 CN1CCN(CC1)C2=Nc3ccccc3Oc4ccc(Cl)cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K17 compound treatment 305446.0 37400.0 0.76 301767.0 40200.0 0.84 1.1276 0.9988 1095093 SPBio_001815 CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K18 compound treatment 307258.0 39200.0 0.79 280382.0 18800.0 0.39 0.8385 0.9469 80 SPBio_001816 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K19 compound treatment 312213.0 44100.0 0.89 312552.0 51000.0 1.06 1.3835 0.9964 1101055 SPBio_001817 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K20 compound treatment 295244.0 27200.0 0.55 296094.0 34500.0 0.72 0.8978 0.9914 3173239 SPBio_001818 CC(N/C(=N/C#N)/Nc1ccncc1)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K21 compound treatment 282291.0 14200.0 0.29 297865.0 36300.0 0.76 0.7382 0.9126 2060432 SPBio_001819 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)cc5cc4Cn3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K22 compound treatment 259906.0 -8170.0 -0.17 297127.0 35500.0 0.74 0.4064 0.5357 1000056 SPBio_001820 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K23 mock treatment 286671.0 18600.0 0.38 265278.0 3690.0 0.08 0.3209 0.8341 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 K24 mock treatment 278501.0 10400.0 0.21 235867.0 -25700.0 -0.54 -0.2294 -0.3983 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L01 mock treatment 303897.0 35800.0 0.73 280208.0 18600.0 0.39 0.7878 0.9569 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L02 mock treatment 312425.0 44300.0 0.9 306215.0 44600.0 0.93 1.2932 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L03 compound treatment 331137.0 63100.0 1.28 275827.0 14200.0 0.3 1.1137 0.8486 3079366 SPBio_001821 O[C@@H]1[C@H]2COC(O2)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L04 compound treatment 233360.0 -34700.0 -0.7 314947.0 53400.0 1.11 0.2884 0.2192 2538 SPBio_001822 ClC1C=CC2C1C3(Cl)C(=C(Cl)C2(Cl)C3(Cl)Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L05 compound treatment 408212.0 140000.0 2.84 313047.0 51500.0 1.07 2.7669 0.9112 1516 SPBio_001823 Nc1c2CCCCc2nc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L06 compound treatment 316814.0 48700.0 0.99 315459.0 53900.0 1.12 1.4923 0.998 2539 SPBio_001824 CC1(C)C2(Cl)C(Cl)C1(Cl)C(Cl)(C(Cl)Cl)C(Cl)C2Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L07 compound treatment 309753.0 41700.0 0.84 227647.0 -33900.0 -0.71 0.0975 0.0885 26 SPBio_001825 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L08 compound treatment 310085.0 42000.0 0.85 316962.0 55400.0 1.15 1.4179 0.9889 2541 SPBio_001826 ClC1=C(Cl)C2(Cl)C3COS(=O)OCC3C1(Cl)C2(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L09 compound treatment 321289.0 53200.0 1.08 295038.0 33500.0 0.7 1.2556 0.9776 690 SPBio_001827 CC(C)NCC(O)COc1ccccc1CC=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L10 compound treatment 316441.0 48400.0 0.98 287278.0 25700.0 0.54 1.0718 0.9595 2540 SPBio_001828 ClC1=C(Cl)C2(Cl)C3C4CC(C=C4)C3C1(Cl)C2(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L11 compound treatment 320782.0 52700.0 1.07 282234.0 20600.0 0.43 1.0597 0.92 1395 SPBio_001829 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L12 compound treatment 309372.0 41300.0 0.84 267342.0 5750.0 0.12 0.6768 0.8002 2060152 SPBio_001830 CC(=O)O[C@@H]1CC2C(C)(C)C=CC(=O)[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L13 compound treatment 295787.0 27700.0 0.56 299780.0 38200.0 0.8 0.9599 0.9855 74 SPBio_001831 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L14 compound treatment 335953.0 67900.0 1.38 316959.0 55400.0 1.15 1.7887 0.9962 3198541 SPBio_001832 CC(CCC=C(C)C)C1CC[C@@]2(C)C3=C(CC[C@]12C)C4(C)CC[C@H](OC(=O)C)C(C)(C)C4CC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L15 compound treatment 277572.0 9500.0 0.19 303923.0 42300.0 0.88 0.7598 0.8416 907089 SPBio_001833 Cn1c(=O)n(C)c2ncn(CCCl)c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L16 compound treatment 307533.0 39500.0 0.8 238589.0 -23000.0 -0.48 0.2268 0.2433 2060174 SPBio_001834 CC(=CCc1c2OC(C)(C)C=Cc2c(O)c3c(=O)c(O)c(oc13)c4ccccc4)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L17 compound treatment 325654.0 57600.0 1.17 298213.0 36600.0 0.76 1.3649 0.9788 352677 SPBio_001835 COc1ccccc1N2CCNCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L18 compound treatment 314317.0 46200.0 0.94 270713.0 9130.0 0.19 0.7973 0.8335 3173763 SPBio_001836 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L19 compound treatment 309858.0 41800.0 0.85 272499.0 10900.0 0.23 0.7597 0.8662 718 SPBio_001837 Cn1c(=O)n(C)c2ncn(CCO)c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L20 compound treatment 337339.0 69300.0 1.4 311759.0 50200.0 1.05 1.732 0.9894 1171 SPBio_001838 CC(=O)Oc1ccccc1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L21 compound treatment 310268.0 42200.0 0.86 283868.0 22300.0 0.46 0.933 0.9588 1865 SPBio_001839 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L22 compound treatment 267067.0 -1010.0 -0.02 232025.0 -29600.0 -0.62 -0.45 -0.7302 2060217 SPBio_001840 COc1c(ccc2OC(C)(C)CCc12)C3COc4cc5OC(C)(C)C(O)Cc5cc4C3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L23 mock treatment 264906.0 -3170.0 -0.06 246923.0 -14700.0 -0.31 -0.2615 -0.8375 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 L24 mock treatment 247680.0 -20400.0 -0.41 270939.0 9350.0 0.19 -0.1546 -0.3383 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M01 mock treatment 257124.0 -11000.0 -0.22 273882.0 12300.0 0.26 0.0241 0.0711 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M02 mock treatment 277887.0 9810.0 0.2 308904.0 47300.0 0.99 0.8377 0.833 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M03 compound treatment 285991.0 17900.0 0.36 283444.0 21900.0 0.46 0.5788 0.9937 1091368 SPBio_001841 CNc1ccccc1C(=O)N2CCc3c([nH]c4ccccc34)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M04 compound treatment 244391.0 -23700.0 -0.48 274505.0 12900.0 0.27 -0.1492 -0.2711 918 SPBio_001842 CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M05 compound treatment 381953.0 114000.0 2.31 410244.0 149000.0 3.1 3.8223 0.9895 1015899 SPBio_001843 NCC(=O)CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M06 compound treatment 333770.0 65700.0 1.33 303026.0 41400.0 0.86 1.5522 0.978 693 SPBio_001844 CCN(CC)CCOc1ccc-2c(c1)C(=O)c3cc(OCCN(CC)CC)ccc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M07 compound treatment 331760.0 63700.0 1.29 350563.0 89000.0 1.85 2.2236 0.9844 1001204 SPBio_001845 COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M08 compound treatment 324088.0 56000.0 1.14 370241.0 109000.0 2.26 2.4035 0.9491 2069286 SPBio_001846 CC(C)C(C)/C=C/C(C)[C@H]1CCC2C3=CCC4CC(=O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M09 compound treatment 299865.0 31800.0 0.64 298014.0 36400.0 0.76 0.9923 0.9967 2060486 SPBio_001847 CC(=O)Oc1ccccc1C(=O)Oc2ccccc2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M10 compound treatment 5186.0 -263000.0 -5.33 2593.0 -259000.0 -5.4 -7.5838 -1.0 3054523 SPBio_001848 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M11 compound treatment 272434.0 4360.0 0.09 265730.0 4140.0 0.09 0.1235 0.9999 1000656 SPBio_001849 OC1=C([C@H]2CC[C@@H](CC2)c3ccc(Cl)cc3)C(=O)c4ccccc4C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M12 compound treatment 301793.0 33700.0 0.68 292352.0 30800.0 0.64 0.9365 0.9995 3198536 SPBio_001850 COc1ccc2C[C@H]3N(C)CC[C@]4([C@H]5Oc1c24)C3=CC[C@@H]5O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M13 compound treatment 289972.0 21900.0 0.44 234622.0 -27000.0 -0.56 -0.0834 -0.1164 2060416 SPBio_001851 Sc1nc2ccccc2s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M14 compound treatment 279193.0 11100.0 0.23 293652.0 32100.0 0.67 0.6317 0.8961 1014978 SPBio_001852 OCC(O)C(O)C(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M15 compound treatment 303367.0 35300.0 0.72 252439.0 -9150.0 -0.19 0.3711 0.5013 3079223 SPBio_001853 Cl.NCCS 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M16 compound treatment 348835.0 80800.0 1.64 270440.0 8850.0 0.18 1.2881 0.7818 3079232 SPBio_001854 COc1ccc2c(=O)ccoc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M17 compound treatment 2359.0 -266000.0 -5.39 2194.0 -259000.0 -5.4 -7.6302 -1.0 3172732 SPBio_001855 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M18 compound treatment 331083.0 63000.0 1.28 313086.0 51500.0 1.07 1.6618 0.9962 3198537 SPBio_001856 CC(C)c1c(O)ccc2c1CCC3C(C)(CCCC32C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M19 compound treatment 301703.0 33600.0 0.68 298129.0 36500.0 0.76 1.0203 0.9985 907181 SPBio_001857 NC(=N)NC(=O)c1nc(Cl)c(nc1N)N2CCCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M20 compound treatment 47025.0 -221000.0 -4.48 33836.0 -228000.0 -4.74 -6.5238 -0.9996 1049467 SPBio_001858 COC(=O)c1c(C)cc(OC(=O)c2c(C)cc(O)c(C=O)c2O)c(C)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M21 compound treatment 250152.0 -17900.0 -0.36 266766.0 5180.0 0.11 -0.1807 -0.4766 1734308 SPBio_001859 Oc1cc(O)c2C(=O)C[C@H](Oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M22 compound treatment 288168.0 20100.0 0.41 269428.0 7840.0 0.16 0.4035 0.9195 2069239 SPBio_001860 Cc1cc(O)c2C(=O)c3c(O)c(C)cc(O)c3C(=O)c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M23 mock treatment 267976.0 -99.7 0.0 274308.0 12700.0 0.26 0.186 0.7017 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 M24 mock treatment 315305.0 47200.0 0.96 258152.0 -3440.0 -0.07 0.6264 0.6524 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N01 mock treatment 309499.0 41400.0 0.84 315656.0 54100.0 1.13 1.3903 0.9895 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N02 mock treatment 348679.0 80600.0 1.63 339538.0 78000.0 1.62 2.3037 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N03 compound treatment 307170.0 39100.0 0.79 351493.0 89900.0 1.87 1.8848 0.9268 1055442 SPBio_001861 Nc1nc(O)c2nc(cnc2n1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N04 compound treatment 361132.0 93100.0 1.89 312390.0 50800.0 1.06 2.0823 0.9627 2060172 SPBio_001862 CC1(C)CC2C1CCC3(CBr)CCC4C(CC(=O)O)C(=O)OC24C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N05 compound treatment 313655.0 45600.0 0.92 322668.0 61100.0 1.27 1.5532 0.9876 2060299 SPBio_001863 CC1(C)CC2/C(=C/C=C/C(C)(O)CCC21O)/CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N06 compound treatment 354547.0 86500.0 1.75 340794.0 79200.0 1.65 2.4064 0.9995 1019872 SPBio_001864 COc1cc2COC(=O)c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N07 compound treatment 341710.0 73600.0 1.49 325972.0 64400.0 1.34 2.004 0.9986 2069306 SPBio_001865 C[C@@]12CCC3C(CCC4=CC(=O)C=C[C@]34C)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N08 compound treatment 96803.0 -171000.0 -3.47 198474.0 -63100.0 -1.31 -3.3849 -0.9117 2060193 SPBio_001866 CC1(C)C2CC1C(=C)C(N)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N09 compound treatment 354466.0 86400.0 1.75 335021.0 73400.0 1.53 2.3202 0.9977 3173755 SPBio_001867 C[C@@]12CC(=O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N10 compound treatment 328802.0 60700.0 1.23 323537.0 61900.0 1.29 1.7831 0.9997 2060191 SPBio_001868 CC1(C)CC2C1CCC(=O)C(CCC2=C)C3CC(=O)OC3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N11 compound treatment 343283.0 75200.0 1.52 304781.0 43200.0 0.9 1.7144 0.9684 3177324 SPBio_001869 C[C@@]12CC(=O)C3C(CC[C@@H]4C[C@H](O)CC[C@@]43C)C2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N12 compound treatment 366309.0 98200.0 1.99 362109.0 101000.0 2.09 2.889 0.9997 1114909 SPBio_001870 COc1cc(CC=C)ccc1OC(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N13 compound treatment 307522.0 39400.0 0.8 286717.0 25100.0 0.52 0.9356 0.9789 2069240 SPBio_001871 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CC[C@@H]4C[C@@H](CC[C@]4(C)C3C(=O)C[C@@]21C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N14 compound treatment 284861.0 16800.0 0.34 311276.0 49700.0 1.04 0.9726 0.8926 3054634 SPBio_001872 COc1c(CC=C(C)C)c2OC(C)(C)C=Cc2c3oc(=O)c(c(O)c13)c4ccc(O)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N15 compound treatment 304122.0 36000.0 0.73 280149.0 18600.0 0.39 0.7902 0.9557 2060261 SPBio_001873 CC(C)(O)[C@H]1CC[C@@]2(C)[C@H]1CC[C@@]3(C)[C@@H]2CCC4[C@@]5(C)CCCC(C)(C)C5[C@@H](O)C[C@]43C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N16 compound treatment 448228.0 180000.0 3.65 342733.0 81100.0 1.69 3.7779 0.9387 3174602 SPBio_001874 O=c1[nH]cnc2nc[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N17 compound treatment 309798.0 41700.0 0.85 283870.0 22300.0 0.46 0.9263 0.9601 1506 SPBio_001875 OCc1cc(=O)c(O)co1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N18 compound treatment 283232.0 15200.0 0.31 274664.0 13100.0 0.27 0.4099 0.9982 3174484 SPBio_001876 C[C@@]12CCC3C(CC[C@H]4C[C@@H](O)CC[C@@]43C)C2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N19 compound treatment 300389.0 32300.0 0.66 297887.0 36300.0 0.76 0.9979 0.9974 2060349 SPBio_001877 CCC[C@H]1CC2=C(C[C@@H](CC)CC3=C1C(=O)OC3=O)C(=O)OC2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N20 compound treatment 292042.0 24000.0 0.49 290378.0 28800.0 0.6 0.7677 0.9945 2060302 SPBio_001878 CC(C)CCC[C@@H](C)CCC[C@@H](C)CC/C(=C/CO)/C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N21 compound treatment 314212.0 46100.0 0.94 294906.0 33300.0 0.69 1.1522 0.9892 3198540 SPBio_001879 COC(=O)/C(=C/CC1(OC(C)(C)C2CC3C=C4C(=O)c5cc6C7CC(C)(CCC7=C(C)C)Oc6c(CCC(C)(C)Cl)c5OC241)C3=O)/C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N22 compound treatment 266826.0 -1250.0 -0.03 269297.0 7710.0 0.16 0.0956 0.5883 3174493 SPBio_001880 N[C@H]([C@@H](O)[C@H](O)[C@H](O)CO)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N23 mock treatment 246860.0 -21200.0 -0.43 249232.0 -12400.0 -0.26 -0.4861 -0.9699 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 N24 mock treatment 250550.0 -17500.0 -0.36 244139.0 -17400.0 -0.36 -0.5083 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O01 mock treatment 249775.0 -18300.0 -0.37 282745.0 21200.0 0.44 0.0493 0.0856 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O02 mock treatment 288970.0 20900.0 0.42 258433.0 -3150.0 -0.07 0.253 0.5903 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O03 compound treatment 183058.0 -85000.0 -1.72 125474.0 -136000.0 -2.84 -3.2238 -0.9715 1000094 SPBio_001881 CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O04 compound treatment 301314.0 33200.0 0.67 274394.0 12800.0 0.27 0.6651 0.9178 3079279 SPBio_001882 COC(=O)c1c(C)cc(O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O05 compound treatment 2470.0 -266000.0 -5.38 2482.0 -259000.0 -5.4 -7.6244 -1.0 2101 SPBio_001883 Oc1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O06 compound treatment 264922.0 -3150.0 -0.06 262407.0 819.0 0.02 -0.0331 -0.5008 3055391 SPBio_001884 OC[C@H]1O[C@@H](Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O07 compound treatment 237344.0 -30700.0 -0.62 209967.0 -51600.0 -1.08 -1.201 -0.9663 3480079 SPBio_001885 COc1ccccc1OCCNCC(O)COc2cccc3[nH]c4ccccc4c23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O08 compound treatment 286291.0 18200.0 0.37 291868.0 30300.0 0.63 0.7072 0.9675 3198538 SPBio_001886 COc1cc2OCOc2cc1c3coc4cc(OC)c(OC)cc4c3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O09 compound treatment 291864.0 23800.0 0.48 303448.0 41900.0 0.87 0.9577 0.961 3177524 SPBio_001887 CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@@H](Cc2ccccc2)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O10 compound treatment 292488.0 24400.0 0.49 263047.0 1460.0 0.03 0.3714 0.7491 2060249 SPBio_001888 COc1ccc(cc1)c2coc3c(OC)c(O)ccc3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O11 compound treatment 328736.0 60700.0 1.23 312092.0 50500.0 1.05 1.6136 0.997 1635 SPBio_001889 CCCCC1=NC2(CCCC2)C(=O)N1Cc3ccc(cc3)c4ccccc4c5nnn[nH]5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O12 compound treatment 262183.0 -5890.0 -0.12 261002.0 -586.0 -0.01 -0.0931 -0.7753 3079280 SPBio_001890 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O13 compound treatment 2980.0 -265000.0 -5.37 2863.0 -259000.0 -5.39 -7.6115 -1.0 1000155 SPBio_001891 C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O14 compound treatment 254416.0 -13700.0 -0.28 273324.0 11700.0 0.24 -0.0229 -0.0621 1002679 SPBio_001892 OCC(O)C(O)C(O)C(O)C(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O15 compound treatment 304787.0 36700.0 0.74 291347.0 29800.0 0.62 0.9646 0.9959 1606766 SPBio_001893 CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)c3ccccc3c4nnn[nH]4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O16 compound treatment 287779.0 19700.0 0.4 276050.0 14500.0 0.3 0.4955 0.9903 2060353 SPBio_001894 Cc1c(O)cc(O)c2c(=O)c(coc12)c3ccc(O)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O17 compound treatment 299165.0 31100.0 0.63 315231.0 53600.0 1.12 1.2359 0.9633 3059445 SPBio_001895 CCCCCCCCCCC[C@@H](C[C@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@@H](CC(C)C)NC=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O18 compound treatment 328705.0 60600.0 1.23 270124.0 8540.0 0.18 0.9949 0.8011 2060132 SPBio_001896 CC1=CC(=O)C2C(C)(C)CCC[C@]2(C)[C@@]1(O)CCc3ccoc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O19 compound treatment 286858.0 18800.0 0.38 288247.0 26700.0 0.56 0.662 0.983 3480074 SPBio_001897 CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O20 compound treatment 289728.0 21700.0 0.44 294934.0 33300.0 0.69 0.8016 0.9755 2060134 SPBio_001898 COc1cc2ccc(=O)oc2c3ccoc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O21 compound treatment 243927.0 -24100.0 -0.49 271116.0 9530.0 0.2 -0.2058 -0.3896 907463 SPBio_001899 Cc1nc2ccccn2c(=O)c1CCN3CCC(CC3)C(=O)c4ccc(F)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O22 compound treatment 257735.0 -10300.0 -0.21 269718.0 8130.0 0.17 -0.0285 -0.1056 2060220 SPBio_001900 CC/1[C@H]2C[C@@H](C\C1=N/O)C2(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O23 mock treatment 293409.0 25300.0 0.51 264056.0 2470.0 0.05 0.3995 0.774 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 O24 mock treatment 282848.0 14800.0 0.3 276164.0 14600.0 0.3 0.4265 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P01 mock treatment 278300.0 10200.0 0.21 291772.0 30200.0 0.63 0.5912 0.8929 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P02 mock treatment 298491.0 30400.0 0.62 282474.0 20900.0 0.44 0.7437 0.9854 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P03 compound treatment 364177.0 96100.0 1.95 306238.0 44700.0 0.93 2.0354 0.9428 1087705 SPBio_001901 CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P04 compound treatment 262615.0 -5460.0 -0.11 283539.0 22000.0 0.46 0.2451 0.5209 290 SPBio_001902 CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)C)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P05 compound treatment 2222.0 -266000.0 -5.39 2165.0 -259000.0 -5.4 -7.6326 -1.0 2543 SPBio_001903 CCCCCCCCCc1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P06 compound treatment 290611.0 22500.0 0.46 323325.0 61700.0 1.29 1.2325 0.903 2060293 SPBio_001904 C[C@@H]1CC[C@H]2C(C)(C)C3C[C@@]12CC[C@@]3(C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P07 compound treatment 218620.0 -49500.0 -1.0 215365.0 -46200.0 -0.96 -1.3899 -0.9998 2069261 SPBio_001905 COc1cc2OCC3Oc4c5C=CC(C)(C)Oc5cc(O)c4C(=O)C3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P08 compound treatment 292706.0 24600.0 0.5 275849.0 14300.0 0.3 0.5632 0.9692 1305 SPBio_001906 CCOC(=O)O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccc(OC)cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P09 compound treatment 287301.0 19200.0 0.39 260807.0 -781.0 -0.02 0.2641 0.677 2060403 SPBio_001907 COc1ccc(C2COc3cc(O)ccc3C2)c(OC)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P10 compound treatment 286079.0 18000.0 0.36 283900.0 22300.0 0.46 0.5868 0.9928 2325 SPBio_001908 NC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P11 compound treatment 258004.0 -10100.0 -0.2 268070.0 6480.0 0.14 -0.0489 -0.1997 3079389 SPBio_001909 COc1cc(OC)c(C(=O)c2ccc(O)cc2)c(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P12 compound treatment 271770.0 3690.0 0.07 286004.0 24400.0 0.51 0.4126 0.8026 2544 SPBio_001910 CCOCN(C(=O)CCl)c1c(C)cccc1CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P13 compound treatment 227723.0 -40400.0 -0.82 209769.0 -51800.0 -1.08 -1.3418 -0.9906 2060426 SPBio_001911 COc1c(O)cccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P14 compound treatment 242569.0 -25500.0 -0.52 258973.0 -2610.0 -0.05 -0.4042 -0.7773 1004713 SPBio_001912 CNc1ccccc1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P15 compound treatment 275911.0 7840.0 0.16 272039.0 10500.0 0.22 0.2663 0.988 1402956 SPBio_001913 CC(N)C(O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P16 compound treatment 228916.0 -39200.0 -0.79 218450.0 -43100.0 -0.9 -1.1968 -0.9981 1040795 SPBio_001914 COc1cccc(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P17 compound treatment 224141.0 -43900.0 -0.89 286989.0 25400.0 0.53 -0.2556 -0.2467 1010251 SPBio_001915 O=C(Nc1ccccc1)Nc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P18 compound treatment 255107.0 -13000.0 -0.26 263927.0 2340.0 0.05 -0.1514 -0.5664 2060417 SPBio_001916 CC(=C)C1Cc2c(O1)ccc(C(=O)O)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P19 compound treatment 234712.0 -33400.0 -0.68 259604.0 -1980.0 -0.04 -0.5075 -0.7489 2069279 SPBio_001917 CCC(C)C(NC)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P20 compound treatment 263683.0 -4390.0 -0.09 278530.0 16900.0 0.35 0.1866 0.5126 2060436 SPBio_001918 O=C(CCCCCCCCCCCCC1CCCC1)Nc2ccc(cc2)S(=O)(=O)c3ccc(NC(=O)CCCCCCCCCCCCC4CCCC4)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P21 compound treatment 258524.0 -9550.0 -0.19 278106.0 16500.0 0.34 0.1064 0.2695 2069262 SPBio_001919 COc1cc(/C=C/C=O)cc(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P22 compound treatment 235047.0 -33000.0 -0.67 267860.0 6270.0 0.13 -0.3811 -0.5586 2060448 SPBio_001920 COc1ccc2[C@H](O)[C@H](Cc3ccc(OC)c(OC)c3)COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P23 mock treatment 250870.0 -17200.0 -0.35 259035.0 -2550.0 -0.05 -0.2843 -0.8056 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2163 P24 mock treatment 242112.0 -26000.0 -0.53 261785.0 197.0 0.0 -0.3693 -0.7016 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A01 mock treatment 195825.0 -54300.0 -1.1 213160.0 -20500.0 -0.43 -1.0791 -0.9148 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A02 mock treatment 208201.0 -41900.0 -0.85 221164.0 -12500.0 -0.26 -0.7838 -0.8829 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A03 compound treatment 224293.0 -25800.0 -0.52 211046.0 -22600.0 -0.47 -0.7022 -0.9986 1026119 SPBio_001921 COc1ccc(C(=O)O)c(O)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A04 compound treatment 3315.0 -247000.0 -5.0 3450.0 -230000.0 -4.8 -6.9281 -0.9998 1164875 SPBio_001922 Nc1nc2[nH]nnc2c(=O)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A05 compound treatment 197911.0 -52200.0 -1.06 204784.0 -28800.0 -0.6 -1.1726 -0.9641 2069278 SPBio_001923 Cc1cc(O)c(C=O)c(O)c1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A06 compound treatment 210264.0 -39800.0 -0.81 226564.0 -7050.0 -0.15 -0.6747 -0.8223 923 SPBio_001924 NC(=O)NC1NC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A07 compound treatment 206309.0 -43800.0 -0.89 223560.0 -10100.0 -0.21 -0.7757 -0.8507 3080393 SPBio_001925 COc1ccc(cc1)c2c(O)c3c(OC)c4CCC(C)(C)Oc4cc3oc2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A08 compound treatment 175291.0 -74800.0 -1.52 205991.0 -27600.0 -0.58 -1.4791 -0.912 692 SPBio_001926 CC(=O)Nc1nnc(s1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A09 compound treatment 209389.0 -40700.0 -0.83 217118.0 -16500.0 -0.34 -0.8264 -0.9247 2069280 SPBio_001927 COc1cc(O)ccc1C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A10 compound treatment 219750.0 -30300.0 -0.61 222029.0 -11600.0 -0.24 -0.6055 -0.9166 1714 SPBio_001928 CN(C)C(=N)NC(=N)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A11 compound treatment 254631.0 4550.0 0.09 226748.0 -6870.0 -0.14 -0.036 -0.2115 2060335 SPBio_001929 Oc1ccc2C3Oc4cc5OCOc5cc4C3COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A12 compound treatment 255586.0 5500.0 0.11 225972.0 -7640.0 -0.16 -0.0337 -0.1735 3221455 SPBio_001930 COc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]4(C)CCc5cc(OC)c(OC)cc5C4Cc6ccc(OC)c(OC)c6)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A13 compound treatment 231174.0 -18900.0 -0.38 210830.0 -22800.0 -0.47 -0.6067 -0.9944 3198542 SPBio_001931 COc1ccc(cc1)c2cc(=O)c3c(OC)cc(OC)c(c4cc(ccc4OC)c5cc(=O)c6c(OC)cc(OC)cc6o5)c3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A14 compound treatment 224851.0 -25200.0 -0.51 194834.0 -38800.0 -0.81 -0.933 -0.9757 3064163 SPBio_001932 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A15 compound treatment 216531.0 -33600.0 -0.68 207991.0 -25600.0 -0.53 -0.8585 -0.9928 3080394 SPBio_001933 COc1cc(OC)c2c(=O)c(c(C)oc2c1OC)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A16 compound treatment 235328.0 -14800.0 -0.3 232673.0 -943.0 -0.02 -0.2254 -0.7519 1000042 SPBio_001934 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A17 compound treatment 229476.0 -20600.0 -0.42 215992.0 -17600.0 -0.37 -0.555 -0.9979 2060054 SPBio_001935 CC(=O)OC(OC(=O)C)c1c(OC(=O)C)cc(C)c2C(=O)Oc3c(C)c(OC(=O)C)c4C(=O)OC(OC(=O)C)c4c3Oc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A18 compound treatment 230408.0 -19700.0 -0.4 186188.0 -47400.0 -0.99 -0.9807 -0.9204 807 SPBio_001936 CCCc1ncc(C[n+]2ccccc2C)c(N)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A19 compound treatment 273188.0 23100.0 0.47 217328.0 -16300.0 -0.34 0.0913 0.1578 3173626 SPBio_001937 CC(C)C(C)/C=C/C(C)C1CCC2C3=CC=C4C(C)(C)C(CCC4(C)C3CCC12C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A20 compound treatment 217453.0 -32600.0 -0.66 194955.0 -38700.0 -0.81 -1.0373 -0.9952 931 SPBio_001938 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A21 compound treatment 220453.0 -29600.0 -0.6 212131.0 -21500.0 -0.45 -0.7413 -0.9895 1082584 SPBio_001939 COc1cc2OCc3oc4c5CC(Oc5ccc4c(=O)c3-c2cc1OC)C(=C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A22 compound treatment 223052.0 -27000.0 -0.55 220422.0 -13200.0 -0.27 -0.5819 -0.9491 3068956 SPBio_001940 NC(=NS(=O)(=O)c1ccc(N)cc1)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A23 mock treatment 189059.0 -61000.0 -1.24 228488.0 -5130.0 -0.11 -0.9503 -0.7653 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 A24 mock treatment 193514.0 -56600.0 -1.15 195866.0 -37800.0 -0.79 -1.367 -0.9831 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B01 mock treatment 258365.0 8280.0 0.17 205153.0 -28500.0 -0.59 -0.3006 -0.4877 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B02 mock treatment 251077.0 993.0 0.02 249606.0 16000.0 0.33 0.2498 0.7485 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B03 compound treatment 236980.0 -13100.0 -0.27 175356.0 -58300.0 -1.21 -1.0461 -0.8419 683 SPBio_001941 Cc1ncc([N+](=O)[O-])n1CCO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B04 compound treatment 237541.0 -12500.0 -0.25 200198.0 -33400.0 -0.7 -0.6721 -0.9068 735 SPBio_001942 NNC(=O)c1ccncc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B05 compound treatment 208389.0 -41700.0 -0.85 196048.0 -37600.0 -0.78 -1.1511 -0.9993 1449 SPBio_001943 CN1[C@@H](CCC1=O)c2cccnc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B06 compound treatment 258195.0 8110.0 0.16 237615.0 4000.0 0.08 0.1752 0.9503 1008060 SPBio_001944 C1CCc2nnnn2CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B07 compound treatment 251986.0 1900.0 0.04 236479.0 2860.0 0.06 0.0694 0.9777 1402 SPBio_001945 CC[N+](C)(C)c1cccc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B08 compound treatment 268959.0 18900.0 0.38 252419.0 18800.0 0.39 0.5476 0.9999 1480 SPBio_001946 Clc1ccc2oc(=O)[nH]c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B09 compound treatment 268684.0 18600.0 0.38 230792.0 -2820.0 -0.06 0.225 0.5896 1029858 SPBio_001947 NC(=N)NC(=N)N1CCOCC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B10 compound treatment 257898.0 7810.0 0.16 244220.0 10600.0 0.22 0.2682 0.9867 1054660 SPBio_001948 Cc1ncc([N+](=O)[O-])n1CC(O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B11 compound treatment 251480.0 1400.0 0.03 233125.0 -491.0 -0.01 0.0128 0.4246 678 SPBio_001949 NCC(CC(=O)O)c1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B12 compound treatment 252989.0 2910.0 0.06 225088.0 -8530.0 -0.18 -0.084 -0.4487 869 SPBio_001950 CCC1(C)CC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B13 compound treatment 242216.0 -7870.0 -0.16 237420.0 3800.0 0.08 -0.0568 -0.3186 839 SPBio_001951 Nc1nc2n(COCCO)cnc2c(=O)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B14 compound treatment 242037.0 -8050.0 -0.16 235528.0 1910.0 0.04 -0.0872 -0.5192 997 SPBio_001952 NCc1ccc(cc1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B15 compound treatment 233673.0 -16400.0 -0.33 235679.0 2060.0 0.04 -0.2049 -0.6107 35 SPBio_001953 CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B16 compound treatment 271687.0 21600.0 0.44 251349.0 17700.0 0.37 0.5709 0.9964 399 SPBio_001954 Nc1nc2ccc(OC(F)(F)F)cc2s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B17 compound treatment 257670.0 7590.0 0.15 211119.0 -22500.0 -0.47 -0.2227 -0.4514 1090166 SPBio_001955 CN(C)c1c(C)n(C)n(c2ccccc2)c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B18 compound treatment 191452.0 -58600.0 -1.19 192355.0 -41300.0 -0.86 -1.4483 -0.9873 3173466 SPBio_001956 [O-][N+](=O)c1ccc(/C=N/N2CC(=O)NC2=O)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B19 compound treatment 3132.0 -247000.0 -5.01 37311.0 -196000.0 -4.09 -6.4319 -0.995 3188940 SPBio_001957 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2[C@H]1C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B20 compound treatment 245250.0 -4830.0 -0.1 220792.0 -12800.0 -0.27 -0.2582 -0.9074 776 SPBio_001958 NNc1nncc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B21 compound treatment 258334.0 8250.0 0.17 247666.0 14000.0 0.29 0.3252 0.9648 1428 SPBio_001959 CC(C)NCC(O)COc1cccc2[nH]ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B22 compound treatment 224512.0 -25600.0 -0.52 211569.0 -22000.0 -0.46 -0.6914 -0.9982 3273 SPBio_001960 NNCCc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B23 mock treatment 208440.0 -41600.0 -0.84 233150.0 -466.0 -0.01 -0.6038 -0.7152 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 B24 mock treatment 201942.0 -48100.0 -0.98 212285.0 -21300.0 -0.44 -1.0044 -0.9366 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C01 mock treatment 217142.0 -32900.0 -0.67 227714.0 -5900.0 -0.12 -0.5592 -0.8235 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C02 mock treatment 255091.0 5010.0 0.1 230125.0 -3490.0 -0.07 0.0203 0.163 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C03 compound treatment 6815.0 -243000.0 -4.93 6367.0 -227000.0 -4.73 -6.8349 -0.9998 2069342 SPBio_001961 COC1=CC(=O)C(=CC1=O)C(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C04 compound treatment 152503.0 -97600.0 -1.98 110650.0 -123000.0 -2.56 -3.2103 -0.9918 2898 SPBio_001962 Cc1cc2CCCS(=O)(=O)c2cc1S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C05 compound treatment 287179.0 37100.0 0.75 282399.0 48800.0 1.02 1.2504 0.989 2060428 SPBio_001963 CCOC(=O)C(=O)C1(Oc2cc(OC)cc(OC)c2C(=O)C1c3ccccc3)C(=O)OCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C06 compound treatment 283413.0 33300.0 0.68 228920.0 -4700.0 -0.1 0.4086 0.5985 3188932 SPBio_001964 CCCCNc1ccc(cc1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C07 compound treatment 260186.0 10100.0 0.2 245886.0 12300.0 0.26 0.3256 0.994 966 SPBio_001965 OC[C@@H]1OC(=O)[C@@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C08 compound treatment 261043.0 11000.0 0.22 230817.0 -2800.0 -0.06 0.1159 0.5044 1131 SPBio_001966 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C09 compound treatment 259136.0 9050.0 0.18 248661.0 15000.0 0.31 0.3514 0.9675 1000247 SPBio_001967 CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O[C@H]3C[C@H](O)[C@H](O[C@H]4CCC(=O)[C@H](C)O4)[C@H](C)O3)[C@H](C)O2)N(C)C)c5c(O)c6C(=O)c7c(O)cccc7C(=O)c6cc5[C@H]1C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C10 compound treatment 221235.0 -28800.0 -0.58 243577.0 9960.0 0.21 -0.2668 -0.43 878 SPBio_001968 CC(=O)NS(=O)(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C11 compound treatment 252391.0 2310.0 0.05 225332.0 -8280.0 -0.17 -0.089 -0.4975 1319 SPBio_001969 NCCCCN 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C12 compound treatment 247491.0 -2590.0 -0.05 224428.0 -9190.0 -0.19 -0.1725 -0.8691 1507 SPBio_001970 CC(N)CCCC(C)(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C13 compound treatment 204587.0 -45500.0 -0.92 186567.0 -47000.0 -0.98 -1.3453 -0.9995 3173726 SPBio_001971 NNC(=O)c1ccncc1.Nc1ccc(C(=O)O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C14 compound treatment 34102.0 -216000.0 -4.38 20658.0 -213000.0 -4.44 -6.2332 -1.0 1175 SPBio_001972 Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C15 compound treatment 237408.0 -12700.0 -0.26 204692.0 -28900.0 -0.6 -0.6078 -0.9278 914 SPBio_001973 OC[C@H]1O[C@@H](OC2c3cccc(O)c3C(=O)c4c(O)cc(CO)cc24)[C@H](O)[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C16 compound treatment 251462.0 1380.0 0.03 235513.0 1900.0 0.04 0.0477 0.9856 1079 SPBio_001974 N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C17 compound treatment 230400.0 -19700.0 -0.4 214912.0 -18700.0 -0.39 -0.5577 -0.9999 768 SPBio_001975 C[N+](C)(C)CCO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C18 compound treatment 11775.0 -238000.0 -4.83 10670.0 -223000.0 -4.64 -6.7004 -0.9998 3068957 SPBio_001976 OC[C@H]1O[C@H](CC1O)n2cc(I)c(=O)[nH]c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C19 compound treatment 252242.0 2160.0 0.04 232207.0 -1410.0 -0.03 0.0102 0.1932 3055573 SPBio_001977 OC[C@H]1OC([C@H](O)[C@@H]1O)n2cnc3c(=O)[nH]cnc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C20 compound treatment 244719.0 -5360.0 -0.11 207351.0 -26300.0 -0.55 -0.4638 -0.8314 3068958 SPBio_001978 CC(C)(CS)C(=O)N1CCC[C@@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C21 compound treatment 246071.0 -4010.0 -0.08 227309.0 -6310.0 -0.13 -0.1504 -0.9734 1193 SPBio_001979 CCOc1ccc(NC(=O)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C22 compound treatment 226310.0 -23800.0 -0.48 214659.0 -19000.0 -0.39 -0.6201 -0.9951 82 SPBio_001980 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C23 mock treatment 237355.0 -12700.0 -0.26 206091.0 -27500.0 -0.57 -0.5879 -0.935 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 C24 mock treatment 197084.0 -53000.0 -1.07 194572.0 -39000.0 -0.81 -1.3349 -0.9906 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D01 mock treatment 218359.0 -31700.0 -0.64 244434.0 10800.0 0.23 -0.2954 -0.4335 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D02 mock treatment 254383.0 4300.0 0.09 233261.0 -355.0 -0.01 0.0564 0.6448 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D03 compound treatment 272678.0 22600.0 0.46 263497.0 29900.0 0.62 0.7641 0.9886 715 SPBio_001981 COc1c2ccoc2c(OC)c3oc(C)cc(=O)c13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D04 compound treatment 275880.0 25800.0 0.52 248838.0 15200.0 0.32 0.594 0.9713 1262 SPBio_001982 NC[C@H]1CC[C@@H](CC1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D05 compound treatment 282912.0 32800.0 0.67 283232.0 49600.0 1.03 1.2015 0.9773 1002029 SPBio_001983 CN(C)C/C=C(/c1ccc(Br)cc1)\c2cccnc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D06 compound treatment 290708.0 40600.0 0.82 250361.0 16700.0 0.35 0.829 0.9269 718 SPBio_001984 Cn1c(=O)n(C)c2ncn(CCO)c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D07 compound treatment 256827.0 6740.0 0.14 241177.0 7560.0 0.16 0.208 0.9975 1451360 SPBio_001985 OC(C1CCNCC1)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D08 compound treatment 239679.0 -10400.0 -0.21 249040.0 15400.0 0.32 0.0781 0.2031 3069074 SPBio_001986 N[C@@H]1C[C@H]1c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D09 compound treatment 279518.0 29400.0 0.6 282649.0 49000.0 1.02 1.1443 0.9672 1921128 SPBio_001987 Cn1cnc([N+](=O)[O-])c1Sc2ncnc3nc[nH]c23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D10 compound treatment 240318.0 -9770.0 -0.2 236715.0 3100.0 0.06 -0.0943 -0.4531 3256 SPBio_001988 CCN(CCCc1ccccc1)CCCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D11 compound treatment 202679.0 -47400.0 -0.96 186662.0 -47000.0 -0.98 -1.3712 -1.0 3069004 SPBio_001989 C[C@@]12CC[C@H]3[C@@H](CCC4=CCCC[C@H]34)[C@@H]2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D12 compound treatment 292636.0 42600.0 0.86 237911.0 4290.0 0.09 0.6733 0.7763 3069075 SPBio_001990 OC(=O)COC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D13 compound treatment 237131.0 -13000.0 -0.26 186412.0 -47200.0 -0.98 -0.8811 -0.8656 3060090 SPBio_001991 NC(=N)N/N=C/c1c(Cl)cccc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D14 compound treatment 257392.0 7310.0 0.15 216669.0 -16900.0 -0.35 -0.1449 -0.3784 780 SPBio_001992 CC(C)NNC(=O)c1ccncc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D15 compound treatment 229433.0 -20700.0 -0.42 127181.0 -106000.0 -2.22 -1.8639 -0.826 2038 SPBio_001993 CCN(CC)C(=S)SSC(=S)N(CC)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D16 compound treatment 25036.0 -225000.0 -4.56 23190.0 -210000.0 -4.38 -6.3259 -0.9998 1256 SPBio_001994 Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D17 compound treatment 244804.0 -5280.0 -0.11 225597.0 -8020.0 -0.17 -0.1938 -0.9769 2060486 SPBio_001995 CC(=O)Oc1ccccc1C(=O)Oc2ccccc2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D18 compound treatment 251080.0 996.0 0.02 224188.0 -9430.0 -0.2 -0.1246 -0.6311 741 SPBio_001996 Cc1ccccc1OCC(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D19 compound treatment 227609.0 -22500.0 -0.46 202206.0 -31400.0 -0.65 -0.7849 -0.9843 1434 SPBio_001997 CN1CCN2C(C1)c3ccccc3Cc4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D20 compound treatment 254799.0 4720.0 0.1 202920.0 -30700.0 -0.64 -0.3846 -0.5948 1018627 SPBio_001998 NC(=N)NC(=N)NCCc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D21 compound treatment 253987.0 3900.0 0.08 226999.0 -6620.0 -0.14 -0.0415 -0.2613 440 SPBio_001999 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D22 compound treatment 244064.0 -6020.0 -0.12 203170.0 -30400.0 -0.63 -0.5348 -0.828 1086 SPBio_002000 CC(C)C(=O)Nc1ccc([N+](=O)[O-])c(c1)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D23 mock treatment 259092.0 9010.0 0.18 211832.0 -21800.0 -0.45 -0.1918 -0.392 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 D24 mock treatment 227850.0 -22200.0 -0.45 203360.0 -30300.0 -0.63 -0.7644 -0.9865 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E01 mock treatment 238749.0 -11300.0 -0.23 208487.0 -25100.0 -0.52 -0.5327 -0.9317 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E02 mock treatment 238999.0 -11100.0 -0.22 232404.0 -1210.0 -0.03 -0.1768 -0.7816 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E03 compound treatment 203630.0 -46500.0 -0.94 203252.0 -30400.0 -0.63 -1.1132 -0.9813 939 SPBio_002001 Cc1cccc(Nc2ccccc2C(=O)O)c1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E04 compound treatment 51280.0 -199000.0 -4.03 18319.0 -215000.0 -4.49 -6.0214 -0.9986 944 SPBio_002002 Nc1ccc(cc1)S(=O)(=O)Nc2ccnn2c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E05 compound treatment 19147.0 -231000.0 -4.68 17704.0 -216000.0 -4.5 -6.4911 -0.9998 1668673 SPBio_002003 Nc1ccc(cc1)S(=O)(=O)Nc2ccc(Cl)nn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E06 compound treatment 292646.0 42600.0 0.86 217716.0 -15900.0 -0.33 0.3759 0.4067 3060 SPBio_002004 CC(C)(CO)[C@@H](O)C(=O)NCCCO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E07 compound treatment 18038.0 -232000.0 -4.7 16473.0 -217000.0 -4.52 -6.5252 -0.9998 944 SPBio_002005 Nc1ccc(cc1)S(=O)(=O)Nc2ccnn2c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E08 compound treatment 190663.0 -59400.0 -1.2 140389.0 -93200.0 -1.94 -2.2251 -0.9736 1159 SPBio_002006 Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E09 compound treatment 259130.0 9050.0 0.18 237472.0 3860.0 0.08 0.1865 0.9314 2060488 SPBio_002007 CC(=CCC[C@@](C)(O)C=C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E10 compound treatment 233758.0 -16300.0 -0.33 244120.0 10500.0 0.22 -0.0793 -0.1999 3188934 SPBio_002008 C[C@@]12CC[C@H]3[C@@H](CCC4=C3CCC(=O)C4)[C@@H]2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E11 compound treatment 270563.0 20500.0 0.42 232294.0 -1320.0 -0.03 0.2741 0.6587 3198543 SPBio_002009 [Na+].Oc1ccccc1C(=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E12 compound treatment 341837.0 91800.0 1.86 296729.0 63100.0 1.31 2.245 0.9856 1433 SPBio_002010 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E13 compound treatment 244910.0 -5170.0 -0.1 242313.0 8700.0 0.18 0.0539 0.2577 1603 SPBio_002011 OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E14 compound treatment 265315.0 15200.0 0.31 192794.0 -40800.0 -0.85 -0.383 -0.4233 3068961 SPBio_002012 CN/C(=N/C#N)/NCCSCC1N=CN=C1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E15 compound treatment 218791.0 -31300.0 -0.63 197372.0 -36200.0 -0.76 -0.9825 -0.9962 870 SPBio_002013 OC(=O)/C(=C/c1ccc(O)cc1)/C#N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E16 compound treatment 250898.0 814.0 0.02 242127.0 8510.0 0.18 0.137 0.7696 1432 SPBio_002014 CN(C)CCOC(C)(c1ccccc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E17 compound treatment 289891.0 39800.0 0.81 254577.0 21000.0 0.44 0.8794 0.9584 3055218 SPBio_002015 OCC(O)[C@H]1OC(=O)C(=C1O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E18 compound treatment 234159.0 -15900.0 -0.32 239795.0 6180.0 0.13 -0.1373 -0.3949 1000260 SPBio_002016 CC[C@H](CO)NCCN[C@H](CC)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E19 compound treatment 296980.0 46900.0 0.95 246496.0 12900.0 0.27 0.862 0.8726 3198544 SPBio_002017 CC([C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E20 compound treatment 290583.0 40500.0 0.82 224865.0 -8750.0 -0.18 0.4516 0.537 1108 SPBio_002018 Cc1cc(=O)n(c2ccccc2)n1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E21 compound treatment 269684.0 19600.0 0.4 234067.0 451.0 0.01 0.2876 0.7236 3471107 SPBio_002019 NC(=O)c1cc[n+](CC2=C(N3C(SC2)C(NC(=O)C(c4ccccc4)S(=O)(=O)O)C3=O)C(=O)O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E22 compound treatment 247748.0 -2340.0 -0.05 242609.0 8990.0 0.19 0.099 0.5123 1079457 SPBio_002020 Cc1c(O)c(=O)n(c2ccccc2)n1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E23 mock treatment 257857.0 7770.0 0.16 247321.0 13700.0 0.29 0.3133 0.9608 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 E24 mock treatment 223556.0 -26500.0 -0.54 193367.0 -40200.0 -0.84 -0.9732 -0.977 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F01 mock treatment 271037.0 21000.0 0.42 236399.0 2780.0 0.06 0.3414 0.7962 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F02 mock treatment 284498.0 34400.0 0.7 249302.0 15700.0 0.33 0.7244 0.9403 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F03 compound treatment 5954.0 -244000.0 -4.95 4003.0 -230000.0 -4.78 -6.8821 -0.9999 899 SPBio_002021 CN1CCc2cccc-3c2[C@H]1Cc4ccc(O)c(O)c43 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F04 compound treatment 321948.0 71900.0 1.46 256659.0 23000.0 0.48 1.3696 0.8929 1081 SPBio_002022 Cc1c(N)c(=O)n(c2ccccc2)n1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F05 compound treatment 246578.0 -3510.0 -0.07 218487.0 -15100.0 -0.32 -0.2731 -0.8453 885 SPBio_002023 Clc1ccc2Oc3ccccc3N=C(N4CCNCC4)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F06 compound treatment 291766.0 41700.0 0.85 250124.0 16500.0 0.34 0.8407 0.9215 1274 SPBio_002024 C1CN2C[C@@H](N=C2S1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F07 compound treatment 266454.0 16400.0 0.33 262160.0 28500.0 0.59 0.6552 0.9621 3326 SPBio_002025 CN1CCC(=C2c3ccccc3C=Cc4ccccc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F08 compound treatment 276863.0 26800.0 0.54 230412.0 -3200.0 -0.07 0.3367 0.6155 719 SPBio_002026 CN(CC#C)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F09 compound treatment 294526.0 44400.0 0.9 263852.0 30200.0 0.63 1.0825 0.9847 3177110 SPBio_002027 NC(=Nc1nc(CSCC/C(=N/S(=O)(=O)N)/N)cs1)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F10 compound treatment 253221.0 3140.0 0.06 224224.0 -9390.0 -0.2 -0.0934 -0.4539 1062 SPBio_002028 COc1ccccc1OCC(O)COC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F11 compound treatment 260073.0 9990.0 0.2 283308.0 49700.0 1.04 0.8752 0.8297 3189048 SPBio_002029 C[C@@]12CC[C@H]3[C@@H](CCC4=Cc5oncc5C[C@]34C)[C@@H]2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F12 compound treatment 297127.0 47000.0 0.95 296212.0 62600.0 1.3 1.5965 0.9882 3189063 SPBio_002030 C[C@H]1[C@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)/c2csc(N)n2)C(=O)N1S(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F13 compound treatment 222952.0 -27100.0 -0.55 227676.0 -5940.0 -0.12 -0.4764 -0.8451 3169 SPBio_002031 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F14 compound treatment 3161.0 -247000.0 -5.01 19832.0 -214000.0 -4.45 -6.6889 -0.9983 1337 SPBio_002032 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F15 compound treatment 279643.0 29600.0 0.6 216752.0 -16900.0 -0.35 0.1753 0.2524 3189049 SPBio_002033 C[N+]1([O-])[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F16 compound treatment 237480.0 -12600.0 -0.26 221953.0 -11700.0 -0.24 -0.3525 -0.9997 724 SPBio_002034 CCn1cc(C(=O)O)c(=O)c2ccc(C)nc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F17 compound treatment 267346.0 17300.0 0.35 239119.0 5500.0 0.11 0.3285 0.8921 1386 SPBio_002035 CN1CC(c2ccccc2)c3cccc(N)c3C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F18 compound treatment 239798.0 -10300.0 -0.21 242889.0 9270.0 0.19 -0.0108 -0.0382 3045683 SPBio_002036 C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F19 compound treatment 284038.0 34000.0 0.69 230133.0 -3480.0 -0.07 0.4354 0.6291 907387 SPBio_002037 C[C@@]1(N[C@@H]2Cc3ccccc31)c4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F20 compound treatment 235041.0 -15000.0 -0.3 241287.0 7670.0 0.16 -0.1026 -0.2981 1428839 SPBio_002038 C(Nc1ncnc2[nH]cnc12)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F21 compound treatment 252105.0 2020.0 0.04 225079.0 -8540.0 -0.18 -0.0968 -0.5303 3069006 SPBio_002039 CC(=O)CC(c1ccc(cc1)[N+](=O)[O-])c2c(O)c3ccccc3oc2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F22 compound treatment 239748.0 -10300.0 -0.21 230073.0 -3540.0 -0.07 -0.2004 -0.9019 198 SPBio_002040 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F23 mock treatment 262752.0 12700.0 0.26 239298.0 5680.0 0.12 0.2653 0.9382 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 F24 mock treatment 233715.0 -16400.0 -0.33 208544.0 -25100.0 -0.52 -0.604 -0.976 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G01 mock treatment 238475.0 -11600.0 -0.24 248508.0 14900.0 0.31 0.053 0.136 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G02 mock treatment 257310.0 7230.0 0.15 259518.0 25900.0 0.54 0.4852 0.8677 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G03 compound treatment 249653.0 -431.0 -0.01 229869.0 -3750.0 -0.08 -0.0614 -0.7814 3058484 SPBio_002041 CC(CCC(=O)O)[C@H]1CCC2C3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G04 compound treatment 319783.0 69700.0 1.41 311999.0 78400.0 1.63 2.1538 0.9974 3188935 SPBio_002042 OC[C@@H](NC(=O)C(Cl)Cl)[C@@H](O)c1ccc(cc1)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G05 compound treatment 76665.0 -173000.0 -3.52 150044.0 -83600.0 -1.74 -3.7171 -0.9475 2069269 SPBio_002043 COC(=O)CCC(C)C1CCC2C3CCC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G06 compound treatment 269972.0 19900.0 0.4 219666.0 -14000.0 -0.29 0.0796 0.1602 2702 SPBio_002044 COc1cc(C)nn1c2nc(C)cc(OC)n2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G07 compound treatment 265044.0 15000.0 0.3 260018.0 26400.0 0.55 0.6034 0.9606 3059164 SPBio_002045 CC(C)CCCC(C)C1CCC2C3CC[C@H]4CC(=O)CC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G08 compound treatment 265316.0 15200.0 0.31 250441.0 16800.0 0.35 0.4662 0.998 697 SPBio_002046 Cn1c(=O)n(C)c2ncn(CC(O)CO)c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G09 compound treatment 145715.0 -104000.0 -2.12 135210.0 -98400.0 -2.05 -2.9458 -0.9999 2060111 SPBio_002047 COc1cc(O)c(cc1O)C(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G10 compound treatment 289851.0 39800.0 0.81 252141.0 18500.0 0.39 0.843 0.9431 1061 SPBio_002048 Nc1nc(N)c2nc(c(N)nc2n1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G11 compound treatment 278791.0 28700.0 0.58 240127.0 6510.0 0.14 0.5074 0.8492 2069324 SPBio_002049 COc1cc(/C=C/C(=O)O)cc(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G12 compound treatment 239155.0 -10900.0 -0.22 242394.0 8780.0 0.18 -0.0274 -0.0952 1186 SPBio_002050 Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G13 compound treatment 250927.0 843.0 0.02 255494.0 21900.0 0.46 0.3344 0.7331 1029168 SPBio_002051 CC(=O)c1ccc[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G14 compound treatment 2383.0 -248000.0 -5.02 3399.0 -230000.0 -4.8 -6.9422 -0.9997 3188936 SPBio_002052 COC1CC(O[C@@H]2[C@H](C)[C@H](OC3OC(C)CC(C3OC(=O)C)N(C)C)[C@H](C)CC4(CO4)C(=O)[C@@H](C)C(OC(=O)C)[C@H](C)[C@H](C)OC(=O)[C@@H]2C)OC(C)C1OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G15 compound treatment 262716.0 12600.0 0.26 244230.0 10600.0 0.22 0.3374 0.9973 2060336 SPBio_002053 CCOc1cccc(c1)C(=O)c2ccc(O)c(O)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G16 compound treatment 12120.0 -238000.0 -4.82 100931.0 -133000.0 -2.76 -5.3658 -0.9651 1259 SPBio_002054 CCc1nc(N)nc(N)c1c2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G17 compound treatment 256472.0 6390.0 0.13 247607.0 14000.0 0.29 0.2977 0.9333 2060244 SPBio_002055 COC1=CC(=O)OC(CCc2ccc(OC)c(OC)c2)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G18 compound treatment 222244.0 -27800.0 -0.56 270148.0 36500.0 0.76 0.1391 0.1468 1270 SPBio_002056 C[N+](C)(C)CCCCCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G19 compound treatment 244630.0 -5450.0 -0.11 237994.0 4380.0 0.09 -0.0137 -0.0955 2060081 SPBio_002057 CC(=CCc1c(O)cc(C)oc1=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G20 compound treatment 255288.0 5200.0 0.11 224569.0 -9050.0 -0.19 -0.0587 -0.2716 1518 SPBio_002058 OC(=O)c1cc(ccc1O)c2ccc(F)cc2F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G21 compound treatment 232635.0 -17400.0 -0.35 236249.0 2630.0 0.05 -0.2113 -0.5904 1091 SPBio_002059 CCc1cn(C2OCC(O)C2CO)c(=O)nc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G22 compound treatment 2651.0 -247000.0 -5.02 2078.0 -232000.0 -4.82 -6.9578 -0.9998 1313 SPBio_002060 Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G23 mock treatment 265059.0 15000.0 0.3 237988.0 4370.0 0.09 0.2791 0.8805 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 G24 mock treatment 252579.0 2500.0 0.05 238899.0 5280.0 0.11 0.1136 0.9378 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H01 mock treatment 291428.0 41300.0 0.84 239648.0 6030.0 0.13 0.6815 0.8041 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H02 mock treatment 275335.0 25300.0 0.51 270817.0 37200.0 0.78 0.91 0.9797 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H03 compound treatment 278127.0 28000.0 0.57 257677.0 24100.0 0.5 0.7564 0.998 929 SPBio_002061 Oc1ccc2C[C@H]3N(CC=C)CC[C@]4([C@H]5Oc1c24)[C@@]3(O)CCC5=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H04 compound treatment 289114.0 39000.0 0.79 256248.0 22600.0 0.47 0.8929 0.9694 1535 SPBio_002062 COc1ccc(OC)c(c1)C(O)CNC(=O)CN 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H05 compound treatment 296765.0 46700.0 0.95 239077.0 5460.0 0.11 0.7496 0.7864 918 SPBio_002063 CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H06 compound treatment 286467.0 36400.0 0.74 239282.0 5670.0 0.12 0.605 0.81 370 SPBio_002064 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H07 compound treatment 2941.0 -247000.0 -5.01 2637.0 -231000.0 -4.81 -6.9454 -0.9998 757 SPBio_002065 OC(=O)c1cn(C2CC2)c3cc(N4CCNCC4)c(F)cc3c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H08 compound treatment 257959.0 7880.0 0.16 266606.0 33000.0 0.69 0.5989 0.8488 1266 SPBio_002066 CCn1cc(C(=O)O)c(=O)c2cc3OCOc3cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H09 compound treatment 2410.0 -248000.0 -5.02 2225.0 -231000.0 -4.82 -6.9591 -0.9998 1092 SPBio_002067 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H10 compound treatment 283961.0 33900.0 0.69 246536.0 12900.0 0.27 0.676 0.9164 1298 SPBio_002068 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H11 compound treatment 290700.0 40600.0 0.82 253199.0 19600.0 0.41 0.8707 0.9475 1261 SPBio_002069 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H12 compound treatment 273264.0 23200.0 0.47 249346.0 15700.0 0.33 0.564 0.9845 1482 SPBio_002070 CN1CCc2cc3OCOc3cc2C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H13 compound treatment 306009.0 55900.0 1.13 265548.0 31900.0 0.67 1.2721 0.9677 3189051 SPBio_002071 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@]5([C@H]6Oc1c25)[C@@]3(O)CCC6=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H14 compound treatment 266354.0 16300.0 0.33 231047.0 -2570.0 -0.05 0.1954 0.5847 1331 SPBio_002072 CC(=O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H15 compound treatment 268198.0 18100.0 0.37 231127.0 -2490.0 -0.05 0.223 0.6013 1207 SPBio_002073 CN(C)CCC(c1ccc(Cl)cc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H16 compound treatment 235983.0 -14100.0 -0.29 245763.0 12100.0 0.25 -0.0232 -0.0608 3189174 SPBio_002074 C[C@H](N)[C@H](O)c1cccc(O)c1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H17 compound treatment 289155.0 39100.0 0.79 249000.0 15400.0 0.32 0.7867 0.9207 1027 SPBio_002075 O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CCC6)c54 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H18 compound treatment 293114.0 43000.0 0.87 241408.0 7790.0 0.16 0.7316 0.8245 1523 SPBio_002076 CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H19 compound treatment 278883.0 28800.0 0.58 230409.0 -3210.0 -0.07 0.3656 0.6221 2241 SPBio_002077 COc1ccc(cc1C(=O)NCc2cccnc2)C(=O)NCc3cccnc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H20 compound treatment 263648.0 13600.0 0.27 228739.0 -4880.0 -0.1 0.1226 0.4182 1436 SPBio_002078 CCCNC(C)C(=O)Nc1ccccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H21 compound treatment 286806.0 36700.0 0.74 243558.0 9940.0 0.21 0.6729 0.8708 1002008 SPBio_002079 C[C@@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]2C[C@@H](O)[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H22 compound treatment 271613.0 21500.0 0.44 243179.0 9560.0 0.2 0.4495 0.9369 383 SPBio_002080 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H23 mock treatment 267768.0 17700.0 0.36 248585.0 15000.0 0.31 0.474 0.9976 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 H24 mock treatment 246306.0 -3780.0 -0.08 207520.0 -26100.0 -0.54 -0.4386 -0.7988 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I01 mock treatment 243318.0 -6770.0 -0.14 245950.0 12300.0 0.26 0.0847 0.2908 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I02 mock treatment 255133.0 5050.0 0.1 231400.0 -2220.0 -0.05 0.0397 0.3538 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I03 compound treatment 282734.0 32700.0 0.66 254115.0 20500.0 0.43 0.77 0.9775 3080395 SPBio_002081 CC(C)CCCC(C)C1CCC2C3CC[C@H]4CCCC[C@]4(C)C3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I04 compound treatment 252983.0 2900.0 0.06 220992.0 -12600.0 -0.26 -0.1444 -0.5359 779 SPBio_002082 CCN(CC)CCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I05 compound treatment 296297.0 46200.0 0.94 289020.0 55400.0 1.15 1.4786 0.9946 3526 SPBio_002083 Oc1ccc2ccc(=O)oc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I06 compound treatment 280608.0 30500.0 0.62 255645.0 22000.0 0.46 0.7621 0.9892 2847 SPBio_002084 CC(C)c1cc(OC(=O)C)c(C)cc1OCCN(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I07 compound treatment 236127.0 -14000.0 -0.28 269605.0 36000.0 0.75 0.3301 0.4119 3198545 SPBio_002085 Oc1ccc(/C=C/C=O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I08 compound treatment 281013.0 30900.0 0.63 261301.0 27700.0 0.58 0.8512 0.9991 3068964 SPBio_002086 NCCc1cc[nH]n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I09 compound treatment 299907.0 49800.0 1.01 278272.0 44700.0 0.93 1.3721 0.9992 1008535 SPBio_002087 COc1cccc(C=O)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I10 compound treatment 262146.0 12100.0 0.24 247974.0 14400.0 0.3 0.3844 0.995 1268 SPBio_002088 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3cc(C)on3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I11 compound treatment 27427.0 -223000.0 -4.51 28949.0 -205000.0 -4.26 -6.2068 -0.9996 762 SPBio_002089 COc1cccc(OC)c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I12 compound treatment 4371.0 -246000.0 -4.98 10185.0 -223000.0 -4.65 -6.8137 -0.9994 1000165 SPBio_002090 COc1ccc2cc(ccc2c1)[C@@H](C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I13 compound treatment 290841.0 40800.0 0.83 261941.0 28300.0 0.59 1.0015 0.9864 3055245 SPBio_002091 CCC[C@@H]1CCCCN1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I14 compound treatment 237975.0 -12100.0 -0.25 258330.0 24700.0 0.51 0.1905 0.3339 1083 SPBio_002092 C(C1=NCCN1)c2cccc3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I15 compound treatment 284740.0 34700.0 0.7 228394.0 -5220.0 -0.11 0.4199 0.5906 1496 SPBio_002093 CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I16 compound treatment 222061.0 -28000.0 -0.57 215188.0 -18400.0 -0.38 -0.6732 -0.9818 1821 SPBio_002094 Clc1ccccc1CN2CCc3sccc3C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I17 compound treatment 281211.0 31100.0 0.63 241995.0 8380.0 0.17 0.5696 0.87 1280 SPBio_002095 NCCNC(=O)c1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I18 compound treatment 271696.0 21600.0 0.44 240520.0 6900.0 0.14 0.4115 0.8924 819 SPBio_002096 CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I19 compound treatment 51342.0 -199000.0 -4.03 63619.0 -170000.0 -3.54 -5.3532 -0.9979 1440 SPBio_002097 COc1ccc2cc(CCC(=O)C)ccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I20 compound treatment 251723.0 1640.0 0.03 233008.0 -608.0 -0.01 0.0145 0.4088 3188937 SPBio_002098 CCC(C)(CN(C)C)OC(=O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I21 compound treatment 265021.0 14900.0 0.3 248540.0 14900.0 0.31 0.434 0.9999 1069 SPBio_002099 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I22 compound treatment 260044.0 9960.0 0.2 248517.0 14900.0 0.31 0.3623 0.9783 362 SPBio_002100 CCN(CC)CC(=O)Nc1c(C)cccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I23 mock treatment 270419.0 20300.0 0.41 245248.0 11600.0 0.24 0.4629 0.9679 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 I24 mock treatment 249190.0 -894.0 -0.02 201277.0 -32300.0 -0.67 -0.4892 -0.7259 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J01 mock treatment 255174.0 5090.0 0.1 261143.0 27500.0 0.57 0.4785 0.8212 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J02 mock treatment 259837.0 9750.0 0.2 273011.0 39400.0 0.82 0.7201 0.8531 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J03 compound treatment 295203.0 45100.0 0.91 256099.0 22500.0 0.47 0.978 0.9517 1000273 SPBio_002101 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J04 compound treatment 268818.0 18700.0 0.38 250687.0 17100.0 0.36 0.52 0.9995 1068 SPBio_002102 CN/C(=C\[N+](=O)[O-])/NCCSCc1ccc(CN(C)C)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J05 compound treatment 304355.0 54300.0 1.1 251967.0 18400.0 0.38 1.0483 0.9 3069040 SPBio_002103 CNCC(O)c1ccc(O)c(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J06 compound treatment 212105.0 -38000.0 -0.77 159129.0 -74500.0 -1.55 -1.6417 -0.9477 3069077 SPBio_002104 OC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J07 compound treatment 287291.0 37200.0 0.75 251363.0 17700.0 0.37 0.7948 0.9462 3189053 SPBio_002105 CC(C)CCC(=O)O.C[C@]12CCC[C@H]2[C@H]3[C@H](CC1=O)[C@@]4(C)CCC(=O)C[C@H]4CC3=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J08 compound treatment 317751.0 67700.0 1.37 286354.0 52700.0 1.1 1.7469 0.9939 41 SPBio_002106 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J09 compound treatment 263459.0 13400.0 0.27 253111.0 19500.0 0.41 0.4789 0.9807 1610 SPBio_002107 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J10 compound treatment 246892.0 -3190.0 -0.06 250895.0 17300.0 0.36 0.2088 0.5708 752 SPBio_002108 CC1CCc2cc(F)cc3c(=O)c(cn1c23)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J11 compound treatment 233651.0 -16400.0 -0.33 219019.0 -14600.0 -0.3 -0.4506 -0.999 1465 SPBio_002109 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J12 compound treatment 301951.0 51900.0 1.05 264779.0 31200.0 0.65 1.2026 0.9731 1258696 SPBio_002110 Cc1c(Cl)cccc1Nc2ccccc2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J13 compound treatment 192293.0 -57800.0 -1.17 165485.0 -68100.0 -1.42 -1.8321 -0.9955 1387 SPBio_002111 OC(C1CCCCN1)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J14 compound treatment 307187.0 57100.0 1.16 249877.0 16300.0 0.34 1.0581 0.8772 1123 SPBio_002112 Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J15 compound treatment 9699.0 -240000.0 -4.87 25723.0 -208000.0 -4.33 -6.5084 -0.9983 3487389 SPBio_002113 Clc1ccc(C(Cn2ccnc2)OCc3c(Cl)cccc3Cl)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J16 compound treatment 310947.0 60900.0 1.23 232391.0 -1230.0 -0.03 0.8544 0.6923 3189175 SPBio_002114 COC1=CC(=O)O[C@H](C1)/C=C/c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J17 compound treatment 270041.0 20000.0 0.4 277599.0 44000.0 0.92 0.934 0.9325 3189054 SPBio_002115 CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@]54CCC(=O)O5)[C@H]13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J18 compound treatment 2887.0 -247000.0 -5.01 2279.0 -231000.0 -4.82 -6.9514 -0.9998 1201 SPBio_002116 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J19 compound treatment 282844.0 32800.0 0.66 263054.0 29400.0 0.61 0.9033 0.9992 786 SPBio_002117 CN1CCN(CC(=O)N2c3ccccc3C(=O)Nc4cccnc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J20 compound treatment 276614.0 26500.0 0.54 246890.0 13300.0 0.28 0.5759 0.9522 734 SPBio_002118 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J21 compound treatment 266302.0 16200.0 0.33 245978.0 12400.0 0.26 0.4146 0.9927 1000246 SPBio_002119 C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J22 compound treatment 262831.0 12700.0 0.26 241101.0 7480.0 0.16 0.293 0.9707 1281686 SPBio_002120 COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J23 mock treatment 269233.0 19100.0 0.39 255039.0 21400.0 0.45 0.5901 0.9976 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 J24 mock treatment 254763.0 4680.0 0.09 238900.0 5280.0 0.11 0.1449 0.9973 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K01 mock treatment 237042.0 -13000.0 -0.26 221352.0 -12300.0 -0.26 -0.3676 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K02 mock treatment 254161.0 4080.0 0.08 266257.0 32600.0 0.68 0.5393 0.7873 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K03 compound treatment 288803.0 38700.0 0.78 261469.0 27900.0 0.58 0.9653 0.9889 2060334 SPBio_002121 C[C@H]1[C@@H](O)C[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K04 compound treatment 263409.0 13300.0 0.27 255668.0 22100.0 0.46 0.5159 0.968 1010605 SPBio_002122 COP(=O)(OC)C(O)C(Cl)(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K05 compound treatment 282260.0 32200.0 0.65 260616.0 27000.0 0.56 0.859 0.9973 2060497 SPBio_002123 CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C#N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K06 compound treatment 240331.0 -9750.0 -0.2 231284.0 -2330.0 -0.05 -0.1742 -0.8554 1019 SPBio_002124 NC(=O)N1c2ccccc2C=Cc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K07 compound treatment 261232.0 11100.0 0.23 250845.0 17200.0 0.36 0.4136 0.9751 1765 SPBio_002125 CC1(C)NC(=O)N(C1=O)c2ccc([N+](=O)[O-])c(c2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K08 compound treatment 251895.0 1810.0 0.04 228561.0 -5060.0 -0.11 -0.0485 -0.4349 1401 SPBio_002126 CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K09 compound treatment 272158.0 22100.0 0.45 228906.0 -4710.0 -0.1 0.247 0.5392 3057756 SPBio_002127 C1CCN2C[C@H]3C[C@@H](CN4CCCC[C@H]34)[C@@H]2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K10 compound treatment 314358.0 64300.0 1.3 287177.0 53600.0 1.12 1.7104 0.997 939 SPBio_002128 Cc1cccc(Nc2ccccc2C(=O)O)c1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K11 compound treatment 287667.0 37600.0 0.76 259502.0 25900.0 0.54 0.9201 0.9857 3198546 SPBio_002129 CC(=CCC/C(=C/COC(=O)\C=C\c1ccccc1)/C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K12 compound treatment 277520.0 27400.0 0.56 274570.0 41000.0 0.85 0.9966 0.9785 3186 SPBio_002130 CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)NC2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K13 compound treatment 250498.0 414.0 0.01 229220.0 -4400.0 -0.09 -0.0588 -0.6396 3198547 SPBio_002131 CCCc1nc2c(C)cc(cc2n1Cc3ccc(cc3)c4ccccc4C(=O)O)c5nc6ccccc6n5C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K14 compound treatment 301136.0 51100.0 1.03 284151.0 50500.0 1.05 1.4763 1.0 920 SPBio_002132 CCN1CCCC1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K15 compound treatment 282713.0 32600.0 0.66 257805.0 24200.0 0.5 0.8241 0.991 2060467 SPBio_002133 COc1ccc2C(=O)/C(=C\c3ccc(OC)c(OC)c3)/COc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K16 compound treatment 270897.0 20800.0 0.42 257245.0 23600.0 0.49 0.6464 0.9971 3127 SPBio_002134 CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K17 compound treatment 281008.0 30900.0 0.63 274619.0 41000.0 0.85 1.0473 0.9884 1024489 SPBio_002135 Cc1cc(O)cc(=O)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K18 compound treatment 278104.0 28000.0 0.57 236375.0 2760.0 0.06 0.4423 0.7747 1318 SPBio_002136 CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K19 compound treatment 279369.0 29300.0 0.59 242471.0 8850.0 0.18 0.5502 0.8851 3045136 SPBio_002137 CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)C(CCC3C[C@@H](O)CC(=O)O3)[C@@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K20 compound treatment 280092.0 30000.0 0.61 230827.0 -2790.0 -0.06 0.3891 0.6367 884 SPBio_002138 CN(C)CCC(c1ccccc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K21 compound treatment 151311.0 -98800.0 -2.0 167598.0 -66000.0 -1.38 -2.3884 -0.9832 794 SPBio_002139 Nc1cc(c[nH]c1=O)c2ccncc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K22 compound treatment 283617.0 33500.0 0.68 256765.0 23100.0 0.48 0.8217 0.9859 965 SPBio_002140 C(C1=NCCN1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K23 mock treatment 268562.0 18500.0 0.37 243439.0 9820.0 0.2 0.4096 0.9595 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 K24 mock treatment 264311.0 14200.0 0.29 245446.0 11800.0 0.25 0.3782 0.9969 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L01 mock treatment 270149.0 20100.0 0.41 231230.0 -2390.0 -0.05 0.2525 0.6161 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L02 mock treatment 272853.0 22800.0 0.46 283297.0 49700.0 1.03 1.0583 0.9338 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L03 compound treatment 302172.0 52100.0 1.06 244512.0 10900.0 0.23 0.9072 0.8399 72 SPBio_002141 Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L04 compound treatment 297452.0 47400.0 0.96 254687.0 21100.0 0.44 0.9894 0.9371 347 SPBio_002142 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L05 compound treatment 306500.0 56400.0 1.14 276860.0 43200.0 0.9 1.4458 0.993 4362 SPBio_002143 CN1CCN(CC1)C2=Nc3ccccc3Oc4ccc(Cl)cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L06 compound treatment 279742.0 29700.0 0.6 296447.0 62800.0 1.31 1.3507 0.9377 3069079 SPBio_002144 CN1CCCN=C1/C=C/c2cccs2.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L07 compound treatment 301713.0 51600.0 1.05 255257.0 21600.0 0.45 1.0589 0.9292 3487390 SPBio_002145 OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L08 compound treatment 320634.0 70600.0 1.43 255888.0 22300.0 0.46 1.3394 0.8908 1144 SPBio_002146 O=C1NCC2(CCN(CCc3ccccc3)CC2)O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L09 compound treatment 278838.0 28800.0 0.58 274878.0 41300.0 0.86 1.02 0.9821 355 SPBio_002147 COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L10 compound treatment 306368.0 56300.0 1.14 280515.0 46900.0 0.98 1.4977 0.997 796 SPBio_002148 Cc1ccc(C)c(OCCCC(C)(C)C(=O)O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L11 compound treatment 185184.0 -64900.0 -1.32 17917.0 -216000.0 -4.49 -4.1078 -0.8773 464 SPBio_002149 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L12 compound treatment 263743.0 13700.0 0.28 268335.0 34700.0 0.72 0.7073 0.9132 1346 SPBio_002150 CCN(CC)CCNC(=O)COc1ccc(OC)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L13 compound treatment 264514.0 14400.0 0.29 243565.0 9950.0 0.21 0.3534 0.9858 709 SPBio_002151 COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L14 compound treatment 274736.0 24700.0 0.5 258823.0 25200.0 0.53 0.7247 0.9997 1339 SPBio_002152 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(=O)(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L15 compound treatment 2802.0 -247000.0 -5.01 5329.0 -228000.0 -4.76 -6.9077 -0.9997 3189055 SPBio_002153 CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L16 compound treatment 276010.0 25900.0 0.53 258406.0 24800.0 0.52 0.7368 1.0 1350 SPBio_002154 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L17 compound treatment 247398.0 -2690.0 -0.05 238663.0 5050.0 0.11 0.0358 0.3027 1590 SPBio_002155 CC(C)(C)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L18 compound treatment 319531.0 69400.0 1.41 284034.0 50400.0 1.05 1.7382 0.9896 699 SPBio_002156 OC(=O)CCC(=O)c1ccc(cc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L19 compound treatment 12311.0 -238000.0 -4.82 24353.0 -209000.0 -4.36 -6.4912 -0.9987 3060388 SPBio_002157 CO/N=C(\C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC(=O)C)/c3csc(N)n3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L20 compound treatment 243383.0 -6700.0 -0.14 276370.0 42800.0 0.89 0.5338 0.5924 1209 SPBio_002158 CC(C(=O)O)c1cccc(c1)C(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L21 compound treatment 3496.0 -247000.0 -5.0 3063.0 -231000.0 -4.8 -6.9312 -0.9998 1418 SPBio_002159 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L22 compound treatment 332879.0 82800.0 1.68 278520.0 44900.0 0.94 1.8484 0.9619 3069113 SPBio_002160 CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L23 mock treatment 260535.0 10500.0 0.21 236052.0 2440.0 0.05 0.1857 0.8524 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 L24 mock treatment 255523.0 5440.0 0.11 230359.0 -3260.0 -0.07 0.03 0.2316 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M01 mock treatment 348631.0 98500.0 2.0 225062.0 -8550.0 -0.18 1.2867 0.6415 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M02 mock treatment 286036.0 36000.0 0.73 258318.0 24700.0 0.51 0.8793 0.9855 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M03 compound treatment 279622.0 29500.0 0.6 228904.0 -4710.0 -0.1 0.354 0.5834 1110410 SPBio_002161 COc1ccc(C(=O)C)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M04 compound treatment 289688.0 39600.0 0.8 263809.0 30200.0 0.63 1.0125 0.9927 3188938 SPBio_002162 CN1CCCN=C1/C=C/c2sccc2C.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M05 compound treatment 300302.0 50200.0 1.02 271672.0 38100.0 0.79 1.2805 0.9924 1582 SPBio_002163 O=C1CCO1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M06 compound treatment 286037.0 36000.0 0.73 268343.0 34700.0 0.72 1.027 1.0 3068999 SPBio_002164 CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)C(O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M07 compound treatment 306837.0 56800.0 1.15 321341.0 87700.0 1.83 2.1058 0.9751 104 SPBio_002165 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M08 compound treatment 285188.0 35100.0 0.71 316573.0 83000.0 1.73 1.7253 0.9231 110 SPBio_002166 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M09 compound treatment 293080.0 43000.0 0.87 278205.0 44600.0 0.93 1.2732 0.9995 1000323 SPBio_002167 N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M10 compound treatment 253472.0 3390.0 0.07 222183.0 -11400.0 -0.24 -0.1199 -0.4835 436 SPBio_002168 CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M11 compound treatment 285079.0 35000.0 0.71 269760.0 36100.0 0.75 1.0341 0.9996 1328 SPBio_002169 OC(CCN1CCCCC1)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M12 compound treatment 270757.0 20700.0 0.42 267334.0 33700.0 0.7 0.7931 0.9695 1002 SPBio_002170 CN(C)CCOC(c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M13 compound treatment 287431.0 37300.0 0.76 241897.0 8280.0 0.17 0.6574 0.8465 1510 SPBio_002171 CN(C)CCN(Cc1cccs1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M14 compound treatment 280307.0 30200.0 0.61 243748.0 10100.0 0.21 0.5825 0.8989 728 SPBio_002172 Cc1cc(nnc1NCCN2CCOCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M15 compound treatment 254869.0 4790.0 0.1 239892.0 6280.0 0.13 0.161 0.9892 1318 SPBio_002173 CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M16 compound treatment 31265.0 -219000.0 -4.44 43233.0 -190000.0 -3.97 -5.9413 -0.9984 814 SPBio_002174 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M17 compound treatment 27417.0 -223000.0 -4.51 289267.0 55700.0 1.16 -2.3722 -0.509 3174608 SPBio_002175 COC1C(O)C(O)C(O)[C@@H](O)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M18 compound treatment 278393.0 28300.0 0.57 228022.0 -5590.0 -0.12 0.3234 0.5522 3471598 SPBio_002176 CC(COc1ccccc1)NC(C)C(O)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M19 compound treatment 274856.0 24800.0 0.5 259724.0 26100.0 0.54 0.7397 0.9992 1035250 SPBio_002177 CC(=O)c1c(O)cc(O)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M20 compound treatment 276245.0 26200.0 0.53 257562.0 23900.0 0.5 0.7278 0.9995 1223 SPBio_002178 CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M21 compound treatment 270584.0 20500.0 0.42 252776.0 19200.0 0.4 0.5761 0.9998 3080396 SPBio_002179 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)C(C)C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M22 compound treatment 263860.0 13800.0 0.28 234244.0 628.0 0.01 0.2067 0.7394 971 SPBio_002180 CN(C(=S)Oc1ccc2ccccc2c1)c3cccc(C)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M23 mock treatment 262583.0 12500.0 0.25 230540.0 -3080.0 -0.06 0.1339 0.5121 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 M24 mock treatment 217016.0 -33100.0 -0.67 206491.0 -27100.0 -0.57 -0.8736 -0.9964 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N01 mock treatment 315300.0 65200.0 1.32 249106.0 15500.0 0.32 1.1631 0.8546 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N02 mock treatment 313299.0 63200.0 1.28 268846.0 35200.0 0.73 1.4252 0.965 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N03 compound treatment 280147.0 30100.0 0.61 234953.0 1340.0 0.03 0.4507 0.7386 1000056 SPBio_002181 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N04 compound treatment 29707.0 -220000.0 -4.47 28777.0 -205000.0 -4.27 -6.1766 -0.9997 747 SPBio_002182 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCNCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N05 compound treatment 320946.0 70900.0 1.44 273722.0 40100.0 0.84 1.6066 0.9667 1301 SPBio_002183 OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N06 compound treatment 304423.0 54300.0 1.1 277321.0 43700.0 0.91 1.4228 0.9955 3189176 SPBio_002184 CCCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N07 compound treatment 262482.0 12400.0 0.25 2593.0 -231000.0 -4.81 -3.2255 -0.6693 1360 SPBio_002185 Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N08 compound treatment 308579.0 58500.0 1.19 276128.0 42500.0 0.89 1.4648 0.9897 816 SPBio_002186 Cc1cc(cc(C)c1CC2=NCCN2)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N09 compound treatment 290556.0 40500.0 0.82 269247.0 35600.0 0.74 1.1051 0.9988 80 SPBio_002187 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N10 compound treatment 334798.0 84700.0 1.72 270712.0 37100.0 0.77 1.7608 0.935 1181 SPBio_002188 Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N11 compound treatment 3903.0 -246000.0 -4.99 4081.0 -230000.0 -4.78 -6.9103 -0.9998 901 SPBio_002189 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N12 compound treatment 308658.0 58600.0 1.19 267931.0 34300.0 0.71 1.3452 0.9705 1162 SPBio_002190 Cc1c(NC(=O)c2cccnc2)c(=O)n(c3ccccc3)n1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N13 compound treatment 157250.0 -92800.0 -1.88 155869.0 -77700.0 -1.62 -2.4761 -0.9972 368 SPBio_002191 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N14 compound treatment 306883.0 56800.0 1.15 286261.0 52600.0 1.1 1.5897 0.9997 3069117 SPBio_002192 COC1CC(=O)C[C@@H](C)[C@@]21Oc3c(C2=O)c(OC)cc(OC)c3Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N15 compound treatment 255428.0 5340.0 0.11 267285.0 33700.0 0.7 0.5726 0.8068 783 SPBio_002193 CO[C@@]12C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]2Cc4cn(C)c5cccc1c45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N16 compound treatment 279966.0 29900.0 0.61 270322.0 36700.0 0.76 0.9691 0.9933 386963 SPBio_002194 Clc1ccc(Cn2c(CN3CCCC3)nc4ccccc24)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N17 compound treatment 280608.0 30500.0 0.62 262539.0 28900.0 0.6 0.8636 0.9999 2784 SPBio_002195 C[C@@]12CC[C@H]3[C@@H](C=CC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@]1(O)CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N18 compound treatment 277602.0 27500.0 0.56 268187.0 34600.0 0.72 0.9037 0.992 1075 SPBio_002196 CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N19 compound treatment 267803.0 17700.0 0.36 240777.0 7160.0 0.15 0.3595 0.9242 3189056 SPBio_002197 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN4CCN(C)CC4)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N20 compound treatment 299883.0 49800.0 1.01 247300.0 13700.0 0.29 0.9155 0.8727 1016 SPBio_002198 CN1CCOC(c2ccccc2)c3ccccc3C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N21 compound treatment 289523.0 39400.0 0.8 220169.0 -13400.0 -0.28 0.3673 0.4335 3189057 SPBio_002199 CN1C[C@@H](C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34)C(=O)N[C@]5(C)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C5=O.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N22 compound treatment 243278.0 -6810.0 -0.14 219293.0 -14300.0 -0.3 -0.3086 -0.9386 3046406 SPBio_002200 Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N23 mock treatment 257041.0 6960.0 0.14 228018.0 -5600.0 -0.12 0.0173 0.0943 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 N24 mock treatment 225238.0 -24800.0 -0.5 200792.0 -32800.0 -0.68 -0.8397 -0.9887 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O01 mock treatment 272002.0 21900.0 0.44 238181.0 4560.0 0.1 0.3814 0.8394 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O02 mock treatment 259332.0 9250.0 0.19 242045.0 8430.0 0.18 0.2567 0.9995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O03 compound treatment 273632.0 23500.0 0.48 270699.0 37100.0 0.77 0.8838 0.9732 1572 SPBio_002201 CCCC(C)C1(CC)C(=O)NC(=NC1=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O04 compound treatment 263880.0 13800.0 0.28 254554.0 20900.0 0.44 0.5062 0.9769 1125 SPBio_002202 CCOC(=O)NNc1nncc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O05 compound treatment 277519.0 27400.0 0.56 275049.0 41400.0 0.86 1.0036 0.9774 2060373 SPBio_002203 COc1c(O)cc2c(cc(=O)oc2c1OC)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O06 compound treatment 327133.0 77000.0 1.56 250692.0 17100.0 0.36 1.3561 0.8465 1174 SPBio_002204 CN(C)CCCN1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O07 compound treatment 266200.0 16100.0 0.33 269385.0 35800.0 0.75 0.7579 0.9315 1019888 SPBio_002205 NCC(=O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O08 compound treatment 263114.0 13000.0 0.26 274028.0 40400.0 0.84 0.7821 0.8864 3188939 SPBio_002206 CC/1=C(CC(=O)O)c2cc(F)ccc2\C1=C\c3ccc(cc3)S(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O09 compound treatment 279415.0 29300.0 0.59 265494.0 31900.0 0.66 0.8901 0.9985 2069272 SPBio_002207 CC1C[C@H]2CC(=O)[C@H]3CCCN4CCC[C@H]2[C@]34C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O10 compound treatment 263609.0 13500.0 0.27 251293.0 17700.0 0.37 0.4543 0.9894 1365 SPBio_002208 CN(C)CCC=C1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O11 compound treatment 269109.0 19000.0 0.39 221663.0 -12000.0 -0.25 0.0966 0.2105 2060313 SPBio_002209 C/C/1=C/CC(C)(C)\C=C\C\C(=C\CC1)\C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O12 compound treatment 244555.0 -5530.0 -0.11 255369.0 21800.0 0.45 0.2412 0.5166 872 SPBio_002210 CCN(CC)CCOC(=O)C(c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O13 compound treatment 277898.0 27800.0 0.56 254872.0 21300.0 0.44 0.7118 0.9928 2060368 SPBio_002211 CNC(Cc1c[nH]c2ccccc12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O14 compound treatment 260670.0 10600.0 0.21 244620.0 11000.0 0.23 0.3139 0.9995 969 SPBio_002212 CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O15 compound treatment 251442.0 1360.0 0.03 232959.0 -657.0 -0.01 0.0098 0.3183 1635952 SPBio_002213 Cn1nnnc1SCC2=C(N3C(SC2)C(NC(=O)C(O)c4ccccc4)C3=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O16 compound treatment 276104.0 26000.0 0.53 256308.0 22700.0 0.47 0.7073 0.9985 2080073 SPBio_002214 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O17 compound treatment 290542.0 40500.0 0.82 229657.0 -3960.0 -0.08 0.5216 0.6328 1573 SPBio_002215 CCCC(C)C1(CC)C(=O)NC(=NC1=O)S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O18 compound treatment 252172.0 2090.0 0.04 230390.0 -3230.0 -0.07 -0.0176 -0.2215 731 SPBio_002216 CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O19 compound treatment 250244.0 160.0 0.0 243602.0 9990.0 0.21 0.1494 0.7181 89599 SPBio_002217 OC(=O)c1cc(O)c2c(Cl)cc(Cl)cc2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O20 compound treatment 273735.0 23700.0 0.48 259036.0 25400.0 0.53 0.7135 0.9988 1001312 SPBio_002218 C[N+]1(C)CCC(=C(c2ccccc2)c3ccccc3)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O21 compound treatment 245585.0 -4500.0 -0.09 234998.0 1380.0 0.03 -0.0441 -0.4615 3198548 SPBio_002219 OC(=O)CCC/C=C\C[C@@H]1CO[C@@H](O[C@@H]1c2ccccc2O)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O22 compound treatment 249052.0 -1030.0 -0.02 244700.0 11100.0 0.23 0.1485 0.6404 1053 SPBio_002220 COc1cc(cc(OC)c1OC)C(=O)NCc2ccc(OCCN(C)C)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O23 mock treatment 244418.0 -5670.0 -0.11 247014.0 13400.0 0.28 0.1161 0.3848 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 O24 mock treatment 259847.0 9760.0 0.2 218252.0 -15400.0 -0.32 -0.0864 -0.2295 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P01 mock treatment 264482.0 14400.0 0.29 233202.0 -414.0 -0.01 0.2003 0.6859 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P02 mock treatment 283517.0 33400.0 0.68 252732.0 19100.0 0.4 0.7609 0.9679 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P03 compound treatment 3671.0 -246000.0 -5.0 2730.0 -231000.0 -4.81 -6.9336 -0.9998 3069044 SPBio_002221 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P04 compound treatment 270480.0 20400.0 0.41 287076.0 53500.0 1.11 1.0799 0.909 805 SPBio_002222 CCc1cccc2c3CCOC(CC)(CC(=O)O)c3[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P05 compound treatment 2979.0 -247000.0 -5.01 3531.0 -230000.0 -4.79 -6.9317 -0.9998 3189058 SPBio_002223 COC1CC(O[C@H]2[C@H](C)[C@@H](OC3OC(C)CC(C3O)N(C)C)[C@@H](C)C[C@]4(CO4)C(=O)[C@H](C)[C@@H](O)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)OC(C)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P06 compound treatment 278933.0 28800.0 0.58 278154.0 44500.0 0.93 1.0696 0.9752 3069144 SPBio_002224 C[N+]1([O-])[C@H]2C[C@@H](C[C@@H]1[C@H]3O[C@H]32)OC(=O)[C@H](CO)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P07 compound treatment 3958.0 -246000.0 -4.99 2661.0 -231000.0 -4.81 -6.9305 -0.9998 3189059 SPBio_002225 CCC(=O)OC1C(C)OC(CC1(C)O)OC2C(C)OC(O[C@H]3[C@@H](CC=O)C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](OC(=O)CC)[C@@H]3OC)C(O)C2N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P08 compound treatment 275353.0 25300.0 0.51 277808.0 44200.0 0.92 1.0132 0.9617 1000200 SPBio_002226 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)[C@@H](CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P09 compound treatment 6148.0 -244000.0 -4.95 2312.0 -231000.0 -4.82 -6.9042 -0.9999 3069045 SPBio_002227 CO[C@H]1[C@@H](CC(=O)O[C@H](C)C/C=C/C=C/[C@H](O)[C@H](C)C[C@H](CC=O)[C@@H]1OC2OC(C)C(OC3CC(C)(O)C(OC(=O)CC(C)C)C(C)O3)C(C2O)N(C)C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P10 compound treatment 226926.0 -23200.0 -0.47 241022.0 7410.0 0.15 -0.2229 -0.451 3487401 SPBio_002228 NC(=O)OCC(O)COc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P11 compound treatment 241564.0 -8520.0 -0.17 236762.0 3150.0 0.07 -0.0758 -0.4103 3189060 SPBio_002229 CC(=O)O[C@@H]1C2=C(C)[C@@H](C[C@](O)([C@H](OC(=O)c3ccccc3)[C@H]4[C@]5(CO[C@H]5C[C@@H](O)[C@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@@H](O)[C@H](NC(=O)c6ccccc6)c7ccccc7 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P12 compound treatment 2902.0 -247000.0 -5.01 2165.0 -231000.0 -4.82 -6.9529 -0.9998 3189177 SPBio_002230 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N=C)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P13 compound treatment 265533.0 15400.0 0.31 263175.0 29600.0 0.62 0.6569 0.9508 3189061 SPBio_002231 CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]3C[C@@H](C/C=C(\C)/C(O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P14 compound treatment 247727.0 -2360.0 -0.05 230936.0 -2680.0 -0.06 -0.0733 -0.997 2997 SPBio_002232 COc1cc(cc(OC)c1OC)C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P15 compound treatment 260746.0 10700.0 0.22 231549.0 -2070.0 -0.04 0.1224 0.5553 1257 SPBio_002233 CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P16 compound treatment 163551.0 -86500.0 -1.75 199783.0 -33800.0 -0.7 -1.7389 -0.9198 1323 SPBio_002234 CC1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P17 compound treatment 257512.0 7430.0 0.15 221866.0 -11800.0 -0.24 -0.0666 -0.2318 3069046 SPBio_002235 NCC1OC(COC[C@@H]2C(O)[C@H](OC3C(O)C(N)CC(N)C3OC4OC(CN)C(O)C(O)C4N)O[C@@H]2CO)C(N)C(O)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P18 compound treatment 106265.0 -144000.0 -2.92 101148.0 -132000.0 -2.76 -4.0131 -0.9996 999 SPBio_002236 CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P19 compound treatment 281789.0 31700.0 0.64 255558.0 21900.0 0.46 0.7777 0.9861 3069047 SPBio_002237 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]3NC(=N)N)O[C@@H](C)[C@]2(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P20 compound treatment 234698.0 -15400.0 -0.31 241405.0 7790.0 0.16 -0.1058 -0.301 1443 SPBio_002238 CN(C)CCOC(c1ccccc1)c2ccccc2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P21 compound treatment 220703.0 -29400.0 -0.6 211708.0 -21900.0 -0.46 -0.7439 -0.9914 3189062 SPBio_002239 CN[C@H](C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O)OC[C@]1(C)O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@@H](CC[C@H]3N)[C@@H](C)N)[C@@H]2O)OC[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P22 compound treatment 253674.0 3590.0 0.07 235726.0 2110.0 0.04 0.0825 0.9708 1291 SPBio_002240 CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P23 mock treatment 240753.0 -9330.0 -0.19 247572.0 14000.0 0.29 0.0718 0.2071 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2164 P24 mock treatment 236016.0 -14100.0 -0.29 218995.0 -14600.0 -0.3 -0.4171 -0.9995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A01 mock treatment 220559.0 -28400.0 -0.58 205859.0 -45200.0 -0.94 -1.0731 -0.9722 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A02 mock treatment 205669.0 -43300.0 -0.88 242174.0 -8880.0 -0.19 -0.7516 -0.8377 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A03 compound treatment 237508.0 -11500.0 -0.23 262465.0 11400.0 0.24 0.0037 0.0112 1425 SPBio_002241 CC(N)COc1c(C)cccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A04 compound treatment 172888.0 -76100.0 -1.54 220904.0 -30200.0 -0.63 -1.5349 -0.9216 3189183 SPBio_002242 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@H](O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]3NC(=N)N)O[C@@H](C)[C@]2(O)C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A05 compound treatment 198546.0 -50400.0 -1.02 252499.0 1440.0 0.03 -0.7016 -0.686 3101 SPBio_002243 Cc1c(oc2c(cccc2c1=O)C(=O)OCCN3CCCCC3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A06 compound treatment 212058.0 -36900.0 -0.75 241034.0 -10000.0 -0.21 -0.6768 -0.8711 3480229 SPBio_002244 COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A07 compound treatment 225778.0 -23200.0 -0.47 250477.0 -579.0 -0.01 -0.341 -0.725 769 SPBio_002245 CCCCOc1ccc(CC(=O)NO)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A08 compound treatment 217969.0 -31000.0 -0.63 260602.0 9550.0 0.2 -0.3038 -0.4609 1132 SPBio_002246 CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A09 compound treatment 220290.0 -28700.0 -0.58 199161.0 -51900.0 -1.08 -1.1756 -0.9577 1469 SPBio_002247 CCC1(CCC(=O)NC1=O)c2ccc(N)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A10 compound treatment 223713.0 -25300.0 -0.51 217632.0 -33400.0 -0.7 -0.8545 -0.9886 3068879 SPBio_002248 C[C@@H](N)[C@H](O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A11 compound treatment 219330.0 -29600.0 -0.6 256571.0 5520.0 0.11 -0.3437 -0.5617 858 SPBio_002249 OCC(O)CN1CCN(CC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A12 compound treatment 254771.0 5800.0 0.12 256468.0 5410.0 0.11 0.1628 0.9998 3068880 SPBio_002250 OCC(O)[C@H]1OC(=O)C(O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A13 compound treatment 242320.0 -6650.0 -0.13 252807.0 1750.0 0.04 -0.0696 -0.498 3173239 SPBio_002251 CC(N/C(=N/C#N)/Nc1ccncc1)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A14 compound treatment 183470.0 -65500.0 -1.33 228247.0 -22800.0 -0.48 -1.275 -0.904 800 SPBio_002252 C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A15 compound treatment 224312.0 -24700.0 -0.5 230845.0 -20200.0 -0.42 -0.6512 -0.9964 1185085 SPBio_002253 CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A16 compound treatment 181666.0 -67300.0 -1.36 137338.0 -114000.0 -2.37 -2.64 -0.9657 3063 SPBio_002254 CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A17 compound treatment 238777.0 -10200.0 -0.21 224815.0 -26200.0 -0.55 -0.5327 -0.9115 448 SPBio_002255 Clc1cccc(Cl)c1N=C2NCCN2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A18 compound treatment 236345.0 -12600.0 -0.26 262726.0 11700.0 0.24 -0.0091 -0.0258 3173242 SPBio_002256 Nc1nc2cc(Cl)ccc2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A19 compound treatment 228846.0 -20100.0 -0.41 227757.0 -23300.0 -0.49 -0.6317 -0.9963 1101055 SPBio_002257 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A20 compound treatment 242660.0 -6310.0 -0.13 272653.0 21600.0 0.45 0.2277 0.4867 1516 SPBio_002258 Nc1c2CCCCc2nc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A21 compound treatment 213540.0 -35400.0 -0.72 239589.0 -11500.0 -0.24 -0.6769 -0.8941 690 SPBio_002259 CC(C)NCC(O)COc1ccccc1CC=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A22 compound treatment 205500.0 -43500.0 -0.88 237515.0 -13500.0 -0.28 -0.8227 -0.889 3487402 SPBio_002260 CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A23 mock treatment 204270.0 -44700.0 -0.91 187940.0 -63100.0 -1.31 -1.5706 -0.9835 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 A24 mock treatment 221609.0 -27400.0 -0.55 213305.0 -37800.0 -0.79 -0.9484 -0.9854 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B01 mock treatment 251995.0 3020.0 0.06 238247.0 -12800.0 -0.27 -0.1454 -0.531 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B02 mock treatment 262357.0 13400.0 0.27 266463.0 15400.0 0.32 0.4188 0.9965 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B03 compound treatment 213050.0 -35900.0 -0.73 177293.0 -73800.0 -1.54 -1.6016 -0.9418 2717 SPBio_002261 CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B04 compound treatment 235098.0 -13900.0 -0.28 241835.0 -9220.0 -0.19 -0.3347 -0.9827 429 SPBio_002262 NCCc1c[nH]c2ccc(O)cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B05 compound treatment 269007.0 20000.0 0.41 264757.0 13700.0 0.29 0.489 0.9851 1403 SPBio_002263 COC(=O)C1=CCCN(C)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B06 compound treatment 2695.0 -246000.0 -4.99 2202.0 -249000.0 -5.18 -7.1963 -0.9998 1000242 SPBio_002264 CN(C)CCn1nnnc1SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cc4csc(N)n4)C3=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B07 compound treatment 249616.0 643.0 0.01 282059.0 31000.0 0.65 0.4659 0.7212 1000219 SPBio_002265 N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B08 compound treatment 265929.0 17000.0 0.34 242528.0 -8530.0 -0.18 0.1174 0.3035 3189438 SPBio_002266 Cc1n[nH]c(=O)[nH]c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B09 compound treatment 248324.0 -649.0 -0.01 244497.0 -6560.0 -0.14 -0.1059 -0.7716 1001661 SPBio_002267 CC(C)CCC[C@H](C)CCC[C@H](C)CCC[C@@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B10 compound treatment 234503.0 -14500.0 -0.29 279468.0 28400.0 0.59 0.2111 0.3196 1077918 SPBio_002268 Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B11 compound treatment 262640.0 13700.0 0.28 264125.0 13100.0 0.27 0.3884 1.0 3189307 SPBio_002269 CC(C)CC(NC(=O)[C@H](C)NC(=O)C[C@H](O)C(CC(C)C)NC(=O)[C@@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B12 compound treatment 291494.0 42500.0 0.86 268508.0 17500.0 0.36 0.8666 0.9263 3173761 SPBio_002270 N[C@@H](C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)Cl)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B13 compound treatment 252378.0 3400.0 0.07 255532.0 4480.0 0.09 0.1147 0.989 3068973 SPBio_002271 C(CN1CCOCC1)Nc2cc3CCCc4ccccc4-c3nn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B14 compound treatment 240138.0 -8840.0 -0.18 262301.0 11200.0 0.23 0.039 0.1323 3189439 SPBio_002272 CC(C)CCCCC(=O)N[C@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H](CCN)C(=O)N[C@@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@@H](CNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)C(C)C)[C@@H](C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B15 compound treatment 239668.0 -9310.0 -0.19 261224.0 10200.0 0.21 0.0164 0.0578 1408 SPBio_002273 NC1(CC2CC3CC(C2)C1)C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B16 compound treatment 9414.0 -240000.0 -4.86 2207.0 -249000.0 -5.18 -7.0999 -0.9995 2117312 SPBio_002274 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B17 compound treatment 30606.0 -218000.0 -4.43 20734.0 -230000.0 -4.8 -6.5232 -0.9992 3068976 SPBio_002275 Clc1ccc(CCC(Cn2ccnc2)Sc3c(Cl)cccc3Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B18 compound treatment 234232.0 -14700.0 -0.3 222896.0 -28200.0 -0.59 -0.6261 -0.951 2911 SPBio_002276 CN(C)CC/C=C\1/c2ccccc2CSc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B19 compound treatment 197075.0 -51900.0 -1.05 174494.0 -76600.0 -1.6 -1.8718 -0.9796 26 SPBio_002277 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B20 compound treatment 277139.0 28200.0 0.57 292676.0 41600.0 0.87 1.0169 0.9795 3189440 SPBio_002278 CC(C)(O/N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)C[n+]3ccccc3)\c4csc(N)n4)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B21 compound treatment 245745.0 -3230.0 -0.07 237228.0 -13800.0 -0.29 -0.25 -0.8462 2081486 SPBio_002279 CC1OC(O[C@@H]/2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(=O)O)C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C2)C(O)C(N)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B22 compound treatment 237426.0 -11500.0 -0.23 249292.0 -1760.0 -0.04 -0.1915 -0.8082 3060173 SPBio_002280 NC(=N)NCc1cccc(I)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B23 mock treatment 237576.0 -11400.0 -0.23 228507.0 -22500.0 -0.47 -0.4955 -0.9466 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 B24 mock treatment 233109.0 -15900.0 -0.32 249390.0 -1670.0 -0.03 -0.252 -0.7789 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C01 mock treatment 238725.0 -10200.0 -0.21 226389.0 -24700.0 -0.51 -0.5103 -0.9206 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C02 mock treatment 251737.0 2760.0 0.06 272488.0 21400.0 0.45 0.3553 0.7896 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C03 compound treatment 86710.0 -162000.0 -3.29 126781.0 -124000.0 -2.59 -4.1568 -0.993 1282 SPBio_002281 NS(=O)(=O)c1cc2c(N=CNS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C04 compound treatment 139023.0 -110000.0 -2.23 151719.0 -99300.0 -2.07 -3.0395 -0.9993 907527 SPBio_002282 C(C#CCN1CCCC1)N2CCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C05 compound treatment 285221.0 36200.0 0.73 278758.0 27700.0 0.58 0.9277 0.9929 3036 SPBio_002283 OC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C06 compound treatment 274843.0 25900.0 0.52 268756.0 17700.0 0.37 0.6316 0.9851 1486 SPBio_002284 CC(C)NCC(O)COc1ccc(NC(=O)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C07 compound treatment 248756.0 -217.0 0.0 268802.0 17700.0 0.37 0.2583 0.6986 1000286 SPBio_002285 C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C08 compound treatment 240441.0 -8530.0 -0.17 245049.0 -6010.0 -0.13 -0.2108 -0.9874 3189185 SPBio_002286 Cc1cn([C@H]2C[C@@H](N=[N+]=N)[C@@H](CO)O2)c(=O)[nH]c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C09 compound treatment 244617.0 -4360.0 -0.09 244413.0 -6640.0 -0.14 -0.1603 -0.9765 809 SPBio_002287 CNCCC=C1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C10 compound treatment 24596.0 -224000.0 -4.55 24538.0 -227000.0 -4.72 -6.5533 -0.9998 1192 SPBio_002288 Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C11 compound treatment 243504.0 -5470.0 -0.11 244548.0 -6510.0 -0.14 -0.1743 -0.995 112 SPBio_002289 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C12 compound treatment 246949.0 -2020.0 -0.04 242240.0 -8820.0 -0.18 -0.1589 -0.8443 3068881 SPBio_002290 CCCOc1ccccc1c2nc(=O)c3[nH]nnc3[nH]2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C13 compound treatment 257999.0 9030.0 0.18 244304.0 -6750.0 -0.14 0.0299 0.1297 1000009 SPBio_002291 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C14 compound treatment 250237.0 1260.0 0.03 239139.0 -11900.0 -0.25 -0.1574 -0.6308 1471 SPBio_002292 CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C15 compound treatment 240350.0 -8620.0 -0.17 259305.0 8250.0 0.17 -0.0021 -0.0085 104 SPBio_002293 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C16 compound treatment 235124.0 -13800.0 -0.28 218758.0 -32300.0 -0.67 -0.6743 -0.9249 2431 SPBio_002294 CCN(CC)CCNC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C17 compound treatment 245193.0 -3780.0 -0.08 235206.0 -15800.0 -0.33 -0.2877 -0.8487 746 SPBio_002295 C(N(Cc1ccccc1)c2ccccc2)C3=NCCN3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C18 compound treatment 259228.0 10300.0 0.21 238041.0 -13000.0 -0.27 -0.0447 -0.1309 3189186 SPBio_002296 CNc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C19 compound treatment 59229.0 -190000.0 -3.85 59671.0 -191000.0 -3.99 -5.5393 -0.9998 1485 SPBio_002297 CCC(=C)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C20 compound treatment 203582.0 -45400.0 -0.92 186545.0 -64500.0 -1.34 -1.601 -0.9829 3368 SPBio_002298 NC(=N)NC(=O)Cc1c(Cl)cccc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C21 compound treatment 252437.0 3460.0 0.07 258963.0 7910.0 0.16 0.1661 0.9278 1000106 SPBio_002299 O=C(C1CCCCC1)N2CC3N(CCc4ccccc34)C(=O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C22 compound treatment 207969.0 -41000.0 -0.83 195751.0 -55300.0 -1.15 -1.4025 -0.9872 1001939 SPBio_002300 OCCN1CCN(CC/C=C\2/c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C23 mock treatment 224940.0 -24000.0 -0.49 227921.0 -23100.0 -0.48 -0.6853 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 C24 mock treatment 221512.0 -27500.0 -0.56 193223.0 -57800.0 -1.2 -1.2456 -0.9385 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D01 mock treatment 235935.0 -13000.0 -0.26 244440.0 -6620.0 -0.14 -0.2844 -0.9539 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D02 mock treatment 232700.0 -16300.0 -0.33 278610.0 27600.0 0.57 0.1726 0.2607 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D03 compound treatment 271272.0 22300.0 0.45 253620.0 2560.0 0.05 0.3574 0.7852 3189308 SPBio_002301 C[C@@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D04 compound treatment 260829.0 11900.0 0.24 244495.0 -6560.0 -0.14 0.0733 0.2651 2120971 SPBio_002302 CN1CCCC(CC2c3ccccc3Sc4ccccc24)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D05 compound treatment 290697.0 41700.0 0.85 306120.0 55100.0 1.15 1.4093 0.9888 2117676 SPBio_002303 COc1ccc(C[C@@H]2NC[C@@H](O)[C@@H]2OC(=O)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D06 compound treatment 179919.0 -69100.0 -1.4 103441.0 -148000.0 -3.08 -3.1644 -0.9365 3172716 SPBio_002304 NC(=O)N/N=C/c1ccc(o1)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D07 compound treatment 282751.0 33800.0 0.68 240533.0 -10500.0 -0.22 0.3292 0.4578 1023517 SPBio_002305 NC(=O)Nc1ccc(cc1)[As](=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D08 compound treatment 269157.0 20200.0 0.41 204405.0 -46700.0 -0.97 -0.3979 -0.3773 1782 SPBio_002306 COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D09 compound treatment 206184.0 -42800.0 -0.87 206764.0 -44300.0 -0.92 -1.2659 -0.9995 360 SPBio_002307 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D10 compound treatment 271758.0 22800.0 0.46 278971.0 27900.0 0.58 0.7378 0.9935 912 SPBio_002308 CCCc1cc(=O)[nH]c(=S)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D11 compound treatment 229669.0 -19300.0 -0.39 274087.0 23000.0 0.48 0.0625 0.101 1064663 SPBio_002309 CC(=O)NC(CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D12 compound treatment 244587.0 -4390.0 -0.09 249974.0 -1080.0 -0.02 -0.0788 -0.8592 3189441 SPBio_002310 CC(C)N1CCN(CC1)c2ccc(OC[C@@H]3CO[C@](Cn4cncn4)(O3)c5ccc(Cl)cc5Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D13 compound treatment 41909.0 -207000.0 -4.2 31385.0 -220000.0 -4.58 -6.2043 -0.9991 3189309 SPBio_002311 CCOC(=O)OC(C)OC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](NC(=O)[C@H](N)c3ccccc3)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D14 compound treatment 249746.0 773.0 0.02 277175.0 26100.0 0.54 0.3958 0.7272 3487464 SPBio_002312 CC(C(=O)O)c1ccc(s1)C(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D15 compound treatment 220725.0 -28200.0 -0.57 176378.0 -74700.0 -1.56 -1.505 -0.9078 1960 SPBio_002313 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D16 compound treatment 3890.0 -245000.0 -4.97 4010.0 -247000.0 -5.15 -7.1526 -0.9998 3177604 SPBio_002314 CN[C@H](CC(C)C)C(=O)N[C@@H]1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]6NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(=O)N)NC1=O)c7ccc(O)c(c7)-c8c(O)cc(O)cc8[C@H](NC6=O)C(=O)O)c3O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)c(Cl)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D17 compound treatment 246320.0 -2650.0 -0.05 274770.0 23700.0 0.49 0.3113 0.6264 951 SPBio_002315 OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D18 compound treatment 151290.0 -97700.0 -1.98 162960.0 -88100.0 -1.84 -2.698 -0.9993 1263 SPBio_002316 C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D19 compound treatment 253643.0 4670.0 0.09 215400.0 -35700.0 -0.74 -0.4583 -0.612 982 SPBio_002317 CC(=O)Oc1ccc(cc1)C(c2ccc(OC(=O)C)cc2)c3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D20 compound treatment 244432.0 -4540.0 -0.09 245064.0 -5990.0 -0.12 -0.1534 -0.9888 1489 SPBio_002318 CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D21 compound treatment 250774.0 1800.0 0.04 238429.0 -12600.0 -0.26 -0.1602 -0.6032 3189310 SPBio_002319 CC(C)[C@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@H](O)CCC3=C)\CCC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D22 compound treatment 231804.0 -17200.0 -0.35 244564.0 -6490.0 -0.14 -0.3418 -0.9152 1113307 SPBio_002320 CCN(CC)C(=O)c1ccc(O)c(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D23 mock treatment 224184.0 -24800.0 -0.5 234891.0 -16200.0 -0.34 -0.5935 -0.981 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 D24 mock treatment 214014.0 -35000.0 -0.71 205522.0 -45500.0 -0.95 -1.1719 -0.9897 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E01 mock treatment 249324.0 351.0 0.01 250958.0 -97.8 0.0 0.0036 0.485 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E02 mock treatment 256477.0 7500.0 0.15 250939.0 -117.0 0.0 0.1058 0.6957 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E03 compound treatment 257063.0 8090.0 0.16 273475.0 22400.0 0.47 0.4462 0.9014 3189178 SPBio_002321 C[C@@]12CCC3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E04 compound treatment 274607.0 25600.0 0.52 260173.0 9120.0 0.19 0.5018 0.9069 1188 SPBio_002322 NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E05 compound treatment 251759.0 2790.0 0.06 280738.0 29700.0 0.62 0.4772 0.7685 938 SPBio_002323 Cc1ccc(cc1)/C(=C\CN2CCCC2)/c3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E06 compound treatment 264470.0 15500.0 0.31 292045.0 41000.0 0.85 0.826 0.9078 1510 SPBio_002324 CN(C)CCN(Cc1cccs1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E07 compound treatment 276922.0 27900.0 0.57 231302.0 -19800.0 -0.41 0.1097 0.1566 3060494 SPBio_002325 CN(C)CC/C=C/1\c2ccccc2COc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E08 compound treatment 261340.0 12400.0 0.25 256434.0 5380.0 0.11 0.2565 0.9341 844 SPBio_002326 CNCCCN1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E09 compound treatment 308224.0 59300.0 1.2 276065.0 25000.0 0.52 1.2178 0.9301 1240 SPBio_002327 CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E10 compound treatment 273059.0 24100.0 0.49 271029.0 20000.0 0.42 0.6395 0.9968 2203 SPBio_002328 CN(CCCOc1ccc(Cl)cc1Cl)CC#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E11 compound treatment 254582.0 5610.0 0.11 282150.0 31100.0 0.65 0.5385 0.8187 3189179 SPBio_002329 CN(C)CCOC(c1ccccc1)c2ccccc2.Cn1c(=O)n(C)c2nc(Cl)[n-]c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E12 compound treatment 249225.0 252.0 0.01 278227.0 27200.0 0.57 0.4039 0.7135 1390 SPBio_002330 CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E13 compound treatment 267704.0 18700.0 0.38 286657.0 35600.0 0.74 0.793 0.9517 1112 SPBio_002331 CC(C)N(CCC(C(=O)N)(c1ccccc1)c2ccccn2)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E14 compound treatment 249517.0 544.0 0.01 266007.0 15000.0 0.31 0.228 0.7317 1476 SPBio_002332 CNCCCC1(CCC2c3ccccc31)c4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E15 compound treatment 17211.0 -232000.0 -4.7 20340.0 -231000.0 -4.81 -6.721 -0.9999 1272 SPBio_002333 Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E16 compound treatment 242975.0 -6000.0 -0.12 213059.0 -38000.0 -0.79 -0.6457 -0.8063 3189187 SPBio_002334 Nc1nc(S)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E17 compound treatment 240447.0 -8530.0 -0.17 259590.0 8530.0 0.18 0.0035 0.0141 2359 SPBio_002335 CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@@H]32)n1c5ccccc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E18 compound treatment 232396.0 -16600.0 -0.34 264854.0 13800.0 0.29 -0.0344 -0.0777 3068882 SPBio_002336 CN(C)CC/C=C\1/c2ccccc2Sc3ccc(Cl)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E19 compound treatment 258969.0 10000.0 0.2 281151.0 30100.0 0.63 0.5866 0.8903 1393 SPBio_002337 CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E20 compound treatment 254823.0 5850.0 0.12 281141.0 30100.0 0.63 0.527 0.8262 1000292 SPBio_002338 C[C@H](NCCc1ccc(O)cc1)[C@H](O)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E21 compound treatment 277747.0 28800.0 0.58 282643.0 31600.0 0.66 0.8778 0.9982 1215 SPBio_002339 CC(NCCC(c1ccccc1)c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E22 compound treatment 269427.0 20500.0 0.41 269413.0 18400.0 0.38 0.5636 0.9992 417 SPBio_002340 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E23 mock treatment 254420.0 5450.0 0.11 223238.0 -27800.0 -0.58 -0.3317 -0.5623 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 E24 mock treatment 197239.0 -51700.0 -1.05 237700.0 -13400.0 -0.28 -0.9384 -0.8648 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F01 mock treatment 244417.0 -4560.0 -0.09 248911.0 -2140.0 -0.04 -0.0969 -0.9445 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F02 mock treatment 253024.0 4050.0 0.08 294827.0 43800.0 0.91 0.7029 0.7677 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F03 compound treatment 223880.0 -25100.0 -0.51 150423.0 -101000.0 -2.1 -1.8421 -0.8539 998 SPBio_002341 CCCCCCCCNC(C)C(O)c1ccc(SC(C)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F04 compound treatment 290722.0 41700.0 0.85 265059.0 14000.0 0.29 0.8048 0.8989 1002022 SPBio_002342 NC(CCC(=O)O)C=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F05 compound treatment 315179.0 66200.0 1.34 305534.0 54500.0 1.13 1.7516 0.9965 3069011 SPBio_002343 NCCC(=O)NCCc1c[nH]cn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F06 compound treatment 274050.0 25100.0 0.51 309067.0 58000.0 1.21 1.214 0.926 2121358 SPBio_002344 OC(CCN1CCCCC1)(C2CC3CC2C=C3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F07 compound treatment 309541.0 60600.0 1.23 272100.0 21000.0 0.44 1.1783 0.9037 1409 SPBio_002345 CCCC(C)(COC(=O)N)COC(=O)NC(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F08 compound treatment 285581.0 36600.0 0.74 276917.0 25900.0 0.54 0.9057 0.9876 3487465 SPBio_002346 OC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F09 compound treatment 306701.0 57700.0 1.17 308207.0 57200.0 1.19 1.6694 1.0 3189311 SPBio_002347 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](N)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F10 compound treatment 286865.0 37900.0 0.77 290216.0 39200.0 0.82 1.1201 0.9995 3189442 SPBio_002348 CCc1cccc(CC)c1NC(=O)CN(CC(=O)O)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F11 compound treatment 303627.0 54700.0 1.11 335072.0 84000.0 1.75 2.0211 0.9757 2117409 SPBio_002349 COc1cc(ccc1N=Nc2ccc3c(cc(c(N)c3c2O)S(=O)(=O)O)S(=O)(=O)O)c4ccc(N=Nc5ccc6c(cc(c(N)c6c5O)S(=O)(=O)O)S(=O)(=O)O)c(OC)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F12 compound treatment 245524.0 -3450.0 -0.07 260151.0 9100.0 0.19 0.0845 0.4186 1252 SPBio_002350 CC(C)NCC(O)c1cc(O)cc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F13 compound treatment 292322.0 43300.0 0.88 290493.0 39400.0 0.82 1.2024 0.9994 907205 SPBio_002351 COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F14 compound treatment 266620.0 17600.0 0.36 292594.0 41500.0 0.87 0.8649 0.9236 2080587 SPBio_002352 CNC1C(O)C(OC2C(N)CC(N)C(OC3OC(=CCC3N)CN)C2O)OCC1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F15 compound treatment 264822.0 15800.0 0.32 281270.0 30200.0 0.63 0.6723 0.9513 3173763 SPBio_002353 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F16 compound treatment 264773.0 15800.0 0.32 261941.0 10900.0 0.23 0.3868 0.9857 353 SPBio_002354 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F17 compound treatment 268863.0 19900.0 0.4 273043.0 22000.0 0.46 0.609 0.998 3180147 SPBio_002355 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(O)c(OC)cc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F18 compound treatment 253752.0 4780.0 0.1 278382.0 27300.0 0.57 0.4711 0.8157 2269 SPBio_002356 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F19 compound treatment 249545.0 572.0 0.01 314728.0 63700.0 1.33 0.9462 0.7133 3189312 SPBio_002357 CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@H](O)CCC3=C)/CCC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F20 compound treatment 235768.0 -13200.0 -0.27 229866.0 -21200.0 -0.44 -0.5014 -0.9713 2922 SPBio_002358 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Br)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F21 compound treatment 228104.0 -20900.0 -0.42 271964.0 20900.0 0.44 0.0088 0.0146 3487430 SPBio_002359 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c3cc(Cl)c(N)cc3OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F22 compound treatment 255672.0 6700.0 0.14 263011.0 12000.0 0.25 0.2721 0.9593 1000807 SPBio_002360 CN1CCN(CC1)C(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F23 mock treatment 269802.0 20800.0 0.42 286294.0 35200.0 0.73 0.8177 0.9655 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 F24 mock treatment 221548.0 -27400.0 -0.56 251814.0 758.0 0.02 -0.382 -0.6867 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G01 mock treatment 240935.0 -8040.0 -0.16 258314.0 7260.0 0.15 -0.0083 -0.0374 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G02 mock treatment 255013.0 6040.0 0.12 256976.0 5920.0 0.12 0.1738 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G03 compound treatment 269992.0 21000.0 0.43 255175.0 4120.0 0.09 0.362 0.8328 3069234 SPBio_002361 CC[C@]1(CCCN2CCc3c4[C@@H]21)C[C@](O)(C(=O)OC)n4c5ccccc35 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G04 compound treatment 261327.0 12400.0 0.25 268515.0 17500.0 0.36 0.4343 0.9834 1332 SPBio_002362 NS(=O)(=O)c1cc(ccc1Cl)C2(O)NC(=O)c3ccccc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G05 compound treatment 279378.0 30400.0 0.62 286022.0 35000.0 0.73 0.9509 0.9965 2797 SPBio_002363 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G06 compound treatment 270673.0 21700.0 0.44 268259.0 17200.0 0.36 0.5645 0.9948 3480458 SPBio_002364 CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G07 compound treatment 284294.0 35300.0 0.72 273294.0 22200.0 0.46 0.8339 0.9778 3176928 SPBio_002365 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G08 compound treatment 241575.0 -7400.0 -0.15 241916.0 -9140.0 -0.19 -0.2407 -0.993 1048 SPBio_002366 CCn1cc(C(=O)O)c(=O)c2cc(F)c(nc12)N3CCNCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G09 compound treatment 277443.0 28500.0 0.58 276859.0 25800.0 0.54 0.7882 0.9994 3189180 SPBio_002367 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G10 compound treatment 256833.0 7860.0 0.16 299915.0 48900.0 1.02 0.8324 0.808 1526 SPBio_002368 CC1CCCC(C)N1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G11 compound treatment 260607.0 11600.0 0.24 264980.0 13900.0 0.29 0.3719 0.9947 1172 SPBio_002369 CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G12 compound treatment 236591.0 -12400.0 -0.25 254393.0 3340.0 0.07 -0.1283 -0.4927 1105 SPBio_002370 CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G13 compound treatment 257558.0 8580.0 0.17 275358.0 24300.0 0.51 0.4811 0.8986 404 SPBio_002371 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G14 compound treatment 277901.0 28900.0 0.59 283944.0 32900.0 0.69 0.8992 0.997 3068883 SPBio_002372 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G15 compound treatment 269898.0 20900.0 0.42 262462.0 11400.0 0.24 0.468 0.9625 1100 SPBio_002373 CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G16 compound treatment 2635.0 -246000.0 -4.99 2494.0 -249000.0 -5.18 -7.1929 -0.9998 3189189 SPBio_002374 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G17 compound treatment 205193.0 -43800.0 -0.89 179473.0 -71600.0 -1.49 -1.6821 -0.9693 3172 SPBio_002375 C(/C=C/c1ccccc1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G18 compound treatment 327804.0 78800.0 1.6 321566.0 70500.0 1.47 2.1687 0.9991 1000342 SPBio_002376 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccccc3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G19 compound treatment 271578.0 22600.0 0.46 277655.0 26600.0 0.55 0.7159 0.9955 1001967 SPBio_002377 C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)C=CC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G20 compound treatment 258133.0 9160.0 0.19 254159.0 3100.0 0.06 0.177 0.9003 1000343 SPBio_002378 COc1ccc2C[C@H]3[C@H]4CCCC[C@@]4(CCN3C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G21 compound treatment 232329.0 -16600.0 -0.34 253195.0 2140.0 0.04 -0.2071 -0.6084 3177396 SPBio_002379 COc1ccc2nccc([C@H](O)[C@H]3CC4CCN3C[C@@H]4C=C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G22 compound treatment 260967.0 12000.0 0.24 273811.0 22800.0 0.47 0.5071 0.9519 764 SPBio_002380 Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)n3c(=O)[nH]c4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G23 mock treatment 258833.0 9860.0 0.2 236486.0 -14600.0 -0.3 -0.0733 -0.2017 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 G24 mock treatment 247433.0 -1540.0 -0.03 239009.0 -12000.0 -0.25 -0.1995 -0.789 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H01 mock treatment 268965.0 20000.0 0.41 258679.0 7620.0 0.16 0.3989 0.9163 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H02 mock treatment 280959.0 32000.0 0.65 240947.0 -10100.0 -0.21 0.3096 0.4541 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H03 compound treatment 273670.0 24700.0 0.5 252771.0 1720.0 0.04 0.3793 0.7556 1055132 SPBio_002381 COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H04 compound treatment 264581.0 15600.0 0.32 255853.0 4800.0 0.1 0.2944 0.8872 1095093 SPBio_002382 CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H05 compound treatment 296977.0 48000.0 0.97 278431.0 27400.0 0.57 1.0914 0.9676 3054850 SPBio_002383 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@H]1C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H06 compound treatment 282816.0 33800.0 0.69 301546.0 50500.0 1.05 1.2289 0.9786 2141046 SPBio_002384 CC(=O)N(CC(O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H07 compound treatment 248503.0 -470.0 -0.01 217549.0 -33500.0 -0.7 -0.5003 -0.7167 3189313 SPBio_002385 C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(=O)N)[C@H]2N=C1/C(=C/3\N=C(/C=C/4\N=C(/C(=C\5/[C@@H](CCC(=O)N)[C@](C)(CC(=O)N)[C@@]2(C)N5[Co+]C#N)/C)\[C@@](C)(CC(=O)N)[C@@H]4CCC(=O)N)\C(C)(C)[C@@H]3CCC(=O)N)/C)OP(=O)(O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H08 compound treatment 280797.0 31800.0 0.65 242061.0 -8990.0 -0.19 0.3237 0.4818 3068692 SPBio_002386 CNCCC=C1c2ccccc2C=Cc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H09 compound treatment 293081.0 44100.0 0.89 300119.0 49100.0 1.02 1.355 0.9978 1037 SPBio_002387 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H10 compound treatment 263405.0 14400.0 0.29 293267.0 42200.0 0.88 0.8287 0.8942 889 SPBio_002388 NC(=O)c1cnccn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H11 compound treatment 272313.0 23300.0 0.47 314566.0 63500.0 1.32 1.2702 0.9039 3069049 SPBio_002389 CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C/C=C/C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H12 compound treatment 268108.0 19100.0 0.39 260738.0 9680.0 0.2 0.4169 0.9536 2900 SPBio_002390 CN1C(=O)OC(C)(C)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H13 compound treatment 289007.0 40000.0 0.81 253552.0 2500.0 0.05 0.6107 0.7509 3189314 SPBio_002391 C[C@@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)CC[C@@H]1C5=CC(=O)OC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H14 compound treatment 281709.0 32700.0 0.66 248389.0 -2670.0 -0.06 0.43 0.6457 1607 SPBio_002392 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H15 compound treatment 273977.0 25000.0 0.51 304192.0 53100.0 1.11 1.1412 0.9373 3189315 SPBio_002393 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H16 compound treatment 264145.0 15200.0 0.31 263876.0 12800.0 0.27 0.4063 0.9975 3189443 SPBio_002394 CC1OC(OC/2CC3O[C@@](O)(CC(O)C3C(=O)O)CC(O)C(O)CCC(O)CC(O)CC(O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)/C=C/C=C/CC\C=C\C=C\C=C\C=C2)C(O)C(N)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H17 compound treatment 54115.0 -195000.0 -3.95 71688.0 -179000.0 -3.74 -5.4356 -0.9996 1000279 SPBio_002395 COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H18 compound treatment 279371.0 30400.0 0.62 255071.0 4020.0 0.08 0.4949 0.7958 3060147 SPBio_002396 CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H19 compound treatment 251758.0 2780.0 0.06 263194.0 12100.0 0.25 0.2187 0.8442 3069053 SPBio_002397 CCOC(=O)n1ccn(C)c1=S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H20 compound treatment 2559.0 -246000.0 -5.0 2480.0 -249000.0 -5.18 -7.1942 -0.9998 3068724 SPBio_002398 C[C@@H](O)[C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCNC=N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H21 compound treatment 233565.0 -15400.0 -0.31 259982.0 8930.0 0.19 -0.0894 -0.2459 1001924 SPBio_002399 C[C@@]12CC[C@H]3[C@@H](CC[C@H]4C[C@@H](O)CC[C@@]43C)[C@@H]2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H22 compound treatment 263970.0 15000.0 0.3 275766.0 24700.0 0.51 0.579 0.9684 1448 SPBio_002400 OC(=O)c1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H23 mock treatment 273816.0 24800.0 0.5 253098.0 2040.0 0.04 0.3862 0.7641 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 H24 mock treatment 250449.0 1480.0 0.03 255774.0 4720.0 0.1 0.0907 0.8824 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I01 mock treatment 220133.0 -28800.0 -0.58 262901.0 11800.0 0.25 -0.2389 -0.3765 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I02 mock treatment 275906.0 26900.0 0.55 262028.0 11000.0 0.23 0.5477 0.9253 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I03 compound treatment 247758.0 -1220.0 -0.02 281861.0 30800.0 0.64 0.4364 0.6795 1000235 SPBio_002401 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I04 compound treatment 261396.0 12400.0 0.25 263281.0 12200.0 0.25 0.3582 1.0 3189191 SPBio_002402 CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I05 compound treatment 311635.0 62700.0 1.27 269034.0 18000.0 0.37 1.1631 0.8782 1033 SPBio_002403 CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I06 compound treatment 284498.0 35500.0 0.72 245074.0 -5980.0 -0.12 0.4211 0.5762 3068885 SPBio_002404 C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I07 compound treatment 286597.0 37600.0 0.76 261654.0 10600.0 0.22 0.6955 0.8758 1019722 SPBio_002405 CN1CCCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I08 compound treatment 257411.0 8440.0 0.17 249013.0 -2040.0 -0.04 0.0909 0.5155 1352 SPBio_002406 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I09 compound treatment 278273.0 29300.0 0.59 281348.0 30300.0 0.63 0.8663 0.9995 1164 SPBio_002407 CCN(CC)C(=O)N1CCN(C)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I10 compound treatment 298417.0 49400.0 1.0 253401.0 2350.0 0.05 0.7433 0.7407 3177235 SPBio_002408 CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]3[C@H]1Cc4cn(C)c5cccc3c45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I11 compound treatment 263249.0 14300.0 0.29 261621.0 10600.0 0.22 0.3603 0.9909 1000071 SPBio_002409 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I12 compound treatment 12793.0 -236000.0 -4.79 29714.0 -221000.0 -4.61 -6.6463 -0.9998 3189192 SPBio_002410 CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I13 compound treatment 260188.0 11200.0 0.23 252886.0 1830.0 0.04 0.1877 0.8143 1158 SPBio_002411 C(C(C1CCCCC1)C2CCCCC2)C3CCCCN3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I14 compound treatment 239409.0 -9560.0 -0.19 257250.0 6190.0 0.13 -0.0459 -0.1969 701 SPBio_002412 Nc1c(Br)cc(Br)cc1CNC2CCC(O)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I15 compound treatment 260963.0 12000.0 0.24 270027.0 19000.0 0.4 0.4513 0.9727 3480597 SPBio_002413 CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I16 compound treatment 247014.0 -1960.0 -0.04 230423.0 -20600.0 -0.43 -0.332 -0.7692 705 SPBio_002414 CC(Cc1cccc(c1)C(F)(F)F)NCCOC(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I17 compound treatment 290107.0 41100.0 0.83 292711.0 41700.0 0.87 1.2033 0.9998 1180 SPBio_002415 Fc1ccc(cc1)C(=O)CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I18 compound treatment 252155.0 3180.0 0.06 255168.0 4110.0 0.09 0.1062 0.9902 1000048 SPBio_002416 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I19 compound treatment 94194.0 -155000.0 -3.14 143390.0 -108000.0 -2.24 -3.8048 -0.9865 830 SPBio_002417 COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I20 compound treatment 259420.0 10400.0 0.21 268346.0 17300.0 0.36 0.4045 0.9679 1504 SPBio_002418 O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)c4ncccn4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I21 compound treatment 269890.0 20900.0 0.42 249238.0 -1820.0 -0.04 0.2731 0.6414 753 SPBio_002419 O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I22 compound treatment 79049.0 -170000.0 -3.44 66856.0 -184000.0 -3.84 -5.1493 -0.9986 2873 SPBio_002420 CCc1oc2ccccc2c1C(=O)c3cc(Br)c(O)c(Br)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I23 mock treatment 273877.0 24900.0 0.5 226578.0 -24500.0 -0.51 -0.0036 -0.005 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 I24 mock treatment 248874.0 -99.1 0.0 222783.0 -28300.0 -0.59 -0.4179 -0.7095 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J01 mock treatment 247471.0 -1500.0 -0.03 238238.0 -12800.0 -0.27 -0.2104 -0.7827 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J02 mock treatment 311323.0 62300.0 1.26 249339.0 -1720.0 -0.04 0.8685 0.6868 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J03 compound treatment 291639.0 42700.0 0.86 317507.0 66500.0 1.38 1.5905 0.9744 386 SPBio_002421 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CC[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J04 compound treatment 293465.0 44500.0 0.9 310395.0 59300.0 1.24 1.5119 0.988 821975 SPBio_002422 C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J05 compound treatment 310888.0 61900.0 1.26 357694.0 107000.0 2.22 2.4585 0.9635 2078 SPBio_002423 CCCCc1ccc(nc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J06 compound treatment 2390.0 -247000.0 -5.0 2484.0 -249000.0 -5.18 -7.1965 -0.9998 3189444 SPBio_002424 CCC(C)C1NC2C=Cc3c(cc(nc3C2O)C(=O)OC(C)C4NC(=O)c5csc(n5)C(NC(=O)C6CSC(=N6)/C(=C\C)/NC(=O)C(NC(=O)c7csc(n7)C8(CCC(=NC8c9csc4n9)c%10nc(cs%10)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)NC(=O)C(C)NC(=O)C(=C)NC(=O)C(C)NC1=O)C(C)O)C(C)(O)C(C)O)C(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J07 compound treatment 297487.0 48500.0 0.98 286528.0 35500.0 0.74 1.218 0.9901 3189316 SPBio_002425 COc1ccc(cc1)c2ccc(=N)n(CCCC(=O)O)n2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J08 compound treatment 262770.0 13800.0 0.28 301955.0 50900.0 1.06 0.9476 0.8641 3068727 SPBio_002426 C[S+](=N)([O-])CC[C@H](N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J09 compound treatment 256304.0 7330.0 0.15 295211.0 44200.0 0.92 0.7555 0.8108 3189317 SPBio_002427 C[C@@H]1C(=O)O[C@H]2CC34[C@H]5C[C@@H](C(C)(C)C)C46[C@@H](O)C(=O)O[C@H]6OC3(C(=O)O5)[C@@]12O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J10 compound treatment 307976.0 59000.0 1.2 302608.0 51600.0 1.07 1.6052 0.9986 737 SPBio_002428 c1nc(cs1)c2nc3ccccc3[nH]2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J11 compound treatment 283982.0 35000.0 0.71 284168.0 33100.0 0.69 0.9896 0.9999 716 SPBio_002429 CN(C)CCC=C1c2ccccc2C=Cc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J12 compound treatment 2376.0 -247000.0 -5.0 2304.0 -249000.0 -5.18 -7.1994 -0.9998 3189445 SPBio_002430 CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c4c(O)c(/C=N/N5CCN(C)CC5)c(NC(=O)/C(=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(=O)C)[C@@H]1C)/C)c(O)c4c(O)c3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J13 compound treatment 263231.0 14300.0 0.29 313728.0 62700.0 1.31 1.1276 0.8432 1300555 SPBio_002431 CC(C)(C)NCC(O)COc1cccc2NC(=O)CCc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J14 compound treatment 283183.0 34200.0 0.69 310986.0 59900.0 1.25 1.3732 0.9615 803 SPBio_002432 CCc1cc(ccn1)C(=S)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J15 compound treatment 244596.0 -4380.0 -0.09 292769.0 41700.0 0.87 0.5517 0.6316 2080102 SPBio_002433 C[C@@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J16 compound treatment 243583.0 -5390.0 -0.11 245153.0 -5900.0 -0.12 -0.1642 -0.9983 900 SPBio_002434 CN1C(=C(O)c2sccc2S1(=O)=O)C(=O)Nc3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J17 compound treatment 267391.0 18400.0 0.37 245422.0 -5630.0 -0.12 0.181 0.4625 3069083 SPBio_002435 Nc1c2ccccc2nc3c(O)cccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J18 compound treatment 246808.0 -2170.0 -0.04 296194.0 45100.0 0.94 0.6339 0.6734 3068731 SPBio_002436 CC(=O)Oc1cc(ccc1C(=O)O)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J19 compound treatment 268105.0 19100.0 0.39 253342.0 2290.0 0.05 0.3079 0.788 992 SPBio_002437 CC[C@H]1[C@@H](Cc2cncn2C)COC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J20 compound treatment 285964.0 37000.0 0.75 237152.0 -13900.0 -0.29 0.3254 0.4048 4379 SPBio_002438 CN1CCCCC1CCN2c3ccccc3Sc4ccc(cc24)S(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J21 compound treatment 2645.0 -246000.0 -4.99 3127.0 -248000.0 -5.17 -7.1834 -0.9999 1265 SPBio_002439 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4c(Cl)cccc4Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J22 compound treatment 272545.0 23600.0 0.48 257004.0 5950.0 0.12 0.4255 0.862 1470254 SPBio_002440 Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J23 mock treatment 272670.0 23700.0 0.48 285099.0 34000.0 0.71 0.8412 0.982 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 J24 mock treatment 240542.0 -8430.0 -0.17 230579.0 -20500.0 -0.43 -0.4225 -0.9194 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K01 mock treatment 221208.0 -27800.0 -0.56 264662.0 13600.0 0.28 -0.1976 -0.3135 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K02 mock treatment 270906.0 21900.0 0.44 265759.0 14700.0 0.31 0.531 0.9835 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K03 compound treatment 267638.0 18700.0 0.38 235644.0 -15400.0 -0.32 0.0405 0.0817 3068677 SPBio_002441 OC1=NC(=O)CN1/N=C/c2ccc(o2)c3ccc(cc3)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K04 compound treatment 291888.0 42900.0 0.87 259052.0 8000.0 0.17 0.733 0.8275 771 SPBio_002442 CN1CCC(=C2c3ccsc3C(=O)Cc4ccccc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K05 compound treatment 273235.0 24300.0 0.49 302140.0 51100.0 1.06 1.1003 0.9385 850 SPBio_002443 Clc1cccc(c1)N2CCN(CCCn3nc4ccccn4c3=O)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K06 compound treatment 262705.0 13700.0 0.28 283881.0 32800.0 0.68 0.6804 0.9215 907283 SPBio_002444 NC(=N)N1CCc2ccccc2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K07 compound treatment 332273.0 83300.0 1.69 346294.0 95200.0 1.98 2.5971 0.9968 936 SPBio_002445 OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K08 compound treatment 252174.0 3200.0 0.06 263963.0 12900.0 0.27 0.236 0.8533 1000064 SPBio_002446 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K09 compound treatment 269331.0 20400.0 0.41 272990.0 21900.0 0.46 0.6149 0.9987 1060 SPBio_002447 CN1CCC(=C2c3ccccc3Sc4ccccc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K10 compound treatment 265652.0 16700.0 0.34 242415.0 -8640.0 -0.18 0.1118 0.2919 3189193 SPBio_002448 CC[C@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K11 compound treatment 259850.0 10900.0 0.22 271001.0 19900.0 0.42 0.4497 0.9561 1069 SPBio_002449 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K12 compound treatment 238669.0 -10300.0 -0.21 261039.0 9980.0 0.21 -6.0E-4 -0.0022 1496 SPBio_002450 CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K13 compound treatment 278185.0 29200.0 0.59 294176.0 43100.0 0.9 1.054 0.9796 1113 SPBio_002451 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(=O)O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K14 compound treatment 2443.0 -247000.0 -5.0 2601.0 -248000.0 -5.18 -7.1941 -0.9998 3068886 SPBio_002452 CC(C)/N=c/1\cc2n(c3ccc(Cl)cc3)c4ccccc4nc2cc1Nc5ccc(Cl)cc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K15 compound treatment 281515.0 32500.0 0.66 262737.0 11700.0 0.24 0.6386 0.9081 3068682 SPBio_002453 CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K16 compound treatment 242208.0 -6770.0 -0.14 296945.0 45900.0 0.96 0.579 0.5995 975 SPBio_002454 CCN(CC)CCOC(=O)C(CC1CCCO1)Cc2cccc3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K17 compound treatment 269230.0 20300.0 0.41 328706.0 77700.0 1.62 1.4343 0.8594 1348 SPBio_002455 Clc1ccc(OCC(=O)N2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K18 compound treatment 279657.0 30700.0 0.62 253728.0 2670.0 0.06 0.4792 0.7673 1000105 SPBio_002456 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K19 compound treatment 260062.0 11100.0 0.22 255819.0 4760.0 0.1 0.2291 0.9324 3055129 SPBio_002457 CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@@]21C)c5ccc(cc5)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K20 compound treatment 274892.0 25900.0 0.53 259487.0 8430.0 0.18 0.4957 0.8948 1000143 SPBio_002458 NC(Cn1ccc(=O)c(O)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K21 compound treatment 226892.0 -22100.0 -0.45 240339.0 -10700.0 -0.22 -0.4744 -0.9484 1045066 SPBio_002459 O=C(Nc1ccccc1)OCC(CN2CCCCC2)OC(=O)Nc3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K22 compound treatment 278328.0 29400.0 0.6 272417.0 21400.0 0.45 0.7355 0.9897 2777 SPBio_002460 COc1cc(N)c(Cl)cc1C(=O)NC2CCN(Cc3ccccc3)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K23 mock treatment 268295.0 19300.0 0.39 264784.0 13700.0 0.29 0.4792 0.9881 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 K24 mock treatment 250765.0 1790.0 0.04 272647.0 21600.0 0.45 0.3437 0.7617 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L01 mock treatment 278248.0 29300.0 0.59 223508.0 -27500.0 -0.57 0.0138 0.0168 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L02 mock treatment 275613.0 26600.0 0.54 287299.0 36200.0 0.76 0.9158 0.9865 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L03 compound treatment 265114.0 16100.0 0.33 262389.0 11300.0 0.24 0.3983 0.9872 1055159 SPBio_002461 NC(CC(=O)c1cccc(O)c1N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L04 compound treatment 289342.0 40400.0 0.82 285118.0 34100.0 0.71 1.0805 0.9975 907463 SPBio_002462 Cc1nc2ccccn2c(=O)c1CCN3CCC(CC3)C(=O)c4ccc(F)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L05 compound treatment 274459.0 25500.0 0.52 320766.0 69700.0 1.45 1.3923 0.9032 3189433 SPBio_002463 OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L06 compound treatment 334517.0 85500.0 1.73 340033.0 89000.0 1.85 2.537 0.9994 1024517 SPBio_002464 COc1cc2CCNC(C)c2cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L07 compound treatment 315299.0 66300.0 1.34 332977.0 81900.0 1.71 2.1576 0.993 3069088 SPBio_002465 COC1=C[C@@H]2[C@@H](C3=C2c4c(OC)c(OC)c(OC)cc4CC[C@@H]3NC(=O)C)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L08 compound treatment 292537.0 43600.0 0.88 296516.0 45500.0 0.95 1.2942 0.9994 1193 SPBio_002466 CCOc1ccc(NC(=O)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L09 compound treatment 308224.0 59300.0 1.2 292200.0 41100.0 0.86 1.4555 0.9863 1134 SPBio_002467 CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L10 compound treatment 266633.0 17700.0 0.36 270611.0 19600.0 0.41 0.5412 0.9979 3474094 SPBio_002468 OC1=C(C2CCC(CC2)c3ccc(Cl)cc3)C(=O)c4ccccc4C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L11 compound treatment 274457.0 25500.0 0.52 306982.0 55900.0 1.17 1.1892 0.933 3174101 SPBio_002469 CN1CCc2c(C1)c3ccccc3n2Cc4ccccc4.OS(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L12 compound treatment 298802.0 49800.0 1.01 300301.0 49200.0 1.03 1.4397 1.0 3058468 SPBio_002470 COc1ccc(OC)c(c1)C(O)C(C)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L13 compound treatment 2604.0 -246000.0 -4.99 4891.0 -246000.0 -5.13 -7.158 -0.9999 3174345 SPBio_002471 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@@H]3C(=C)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N.OC(=O)c1cc(ccc1O)S(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L14 compound treatment 283131.0 34200.0 0.69 274966.0 23900.0 0.5 0.8419 0.9869 1001858 SPBio_002472 CC(C)NC[C@H](O)COc1ccc(CC(=O)N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L15 compound treatment 274948.0 26000.0 0.53 250068.0 -988.0 -0.02 0.3578 0.679 1035 SPBio_002473 Cc1cccc(CN2CCN(CC2)C(c3ccccc3)c4ccc(Cl)cc4)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L16 compound treatment 296755.0 47800.0 0.97 315874.0 64800.0 1.35 1.6398 0.9867 904 SPBio_002474 NC(=O)CN1CCCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L17 compound treatment 289384.0 40400.0 0.82 269136.0 18100.0 0.38 0.8456 0.9378 988 SPBio_002475 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L18 compound treatment 283543.0 34600.0 0.7 260635.0 9580.0 0.2 0.6367 0.8737 948 SPBio_002476 O=C1C(C(=O)c2ccccc12)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L19 compound treatment 36346.0 -213000.0 -4.31 40163.0 -211000.0 -4.39 -6.1547 -1.0 449 SPBio_002477 CC1=CC(=O)c2ccccc2C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L20 compound treatment 298827.0 49900.0 1.01 275119.0 24100.0 0.5 1.0691 0.9477 3189446 SPBio_002478 COc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc3CCC(NC(=O)C)c4cc(=O)c(SC)ccc4-c3c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L21 compound treatment 8512.0 -240000.0 -4.87 41430.0 -210000.0 -4.37 -6.5351 -0.9985 3069122 SPBio_002479 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O.COC(N)(CO)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L22 compound treatment 249996.0 1020.0 0.02 265890.0 14800.0 0.31 0.2332 0.7529 3068774 SPBio_002480 Nc1cc(C(=C(Cl)Cl)Cl)c(cc1S(=O)(=O)N)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L23 mock treatment 251532.0 2560.0 0.05 252250.0 1190.0 0.02 0.0543 0.9433 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 L24 mock treatment 257378.0 8400.0 0.17 245971.0 -5080.0 -0.11 0.0456 0.2272 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M01 mock treatment 253788.0 4810.0 0.1 258515.0 7460.0 0.16 0.1789 0.9749 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M02 mock treatment 254218.0 5240.0 0.11 306758.0 55700.0 1.16 0.8957 0.7687 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M03 compound treatment 270314.0 21300.0 0.43 267566.0 16500.0 0.34 0.5491 0.9935 1608 SPBio_002481 NCCCC[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N2CCC[C@H]2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M04 compound treatment 237253.0 -11700.0 -0.24 268813.0 17800.0 0.37 0.0936 0.2128 907366 SPBio_002482 Cc1cccc(C)c1NC(=O)CN2CCN(CCCC(c3ccc(F)cc3)c4ccc(F)cc4)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M05 compound treatment 9828.0 -239000.0 -4.85 42917.0 -208000.0 -4.34 -6.4943 -0.9984 3068878 SPBio_002483 CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M06 compound treatment 288093.0 39100.0 0.79 300134.0 49100.0 1.02 1.2838 0.9921 3480396 SPBio_002484 CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M07 compound treatment 283378.0 34400.0 0.7 300405.0 49300.0 1.03 1.2202 0.9821 907526 SPBio_002485 CN1CCN(CC(=O)N2c3c(C)scc3C(=O)Nc4ccccc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M08 compound treatment 275109.0 26100.0 0.53 284052.0 33000.0 0.69 0.8607 0.9917 86 SPBio_002486 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M09 compound treatment 82395.0 -167000.0 -3.38 162201.0 -88900.0 -1.85 -3.6968 -0.9599 773 SPBio_002487 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M10 compound treatment 299658.0 50700.0 1.03 265385.0 14300.0 0.3 0.9377 0.8763 1210 SPBio_002488 CC(C)(C)c1cc(SC(C)(C)Sc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M11 compound treatment 270884.0 21900.0 0.44 276653.0 25600.0 0.53 0.6912 0.9959 1357 SPBio_002489 CCCCN1CCCCC1C(=O)Nc2c(C)cccc2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M12 compound treatment 269793.0 20800.0 0.42 285723.0 34700.0 0.72 0.8091 0.9673 1135 SPBio_002490 OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M13 compound treatment 292079.0 43100.0 0.87 267450.0 16400.0 0.34 0.8594 0.916 927 SPBio_002491 CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M14 compound treatment 267074.0 18100.0 0.37 196592.0 -54500.0 -1.13 -0.5428 -0.4552 907273 SPBio_002492 Fc1ccc(cc1)C(OCCN2CCN(CCCc3ccccc3)CC2)c4ccc(F)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M15 compound treatment 2926.0 -246000.0 -4.99 3156.0 -248000.0 -5.16 -7.179 -0.9998 876 SPBio_002493 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M16 compound treatment 280465.0 31500.0 0.64 280357.0 29300.0 0.61 0.8831 0.9997 990 SPBio_002494 CCN(CC)CCOCCOC(=O)C1(CCCC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M17 compound treatment 247844.0 -1130.0 -0.02 180797.0 -70300.0 -1.46 -1.0512 -0.7181 2117626 SPBio_002495 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M18 compound treatment 261858.0 12900.0 0.26 160303.0 -90800.0 -1.89 -1.1522 -0.6037 1351 SPBio_002496 Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]3c(C)cc(N)c4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M19 compound treatment 269572.0 20600.0 0.42 270950.0 19900.0 0.41 0.5884 1.0 467359 SPBio_002497 CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M20 compound treatment 268882.0 19900.0 0.4 247747.0 -3310.0 -0.07 0.2367 0.578 3060108 SPBio_002498 CC(=O)N1CCN(CC1)c2ccc(OC[C@H]3CO[C@@](Cn4ccnc4)(O3)c5ccc(Cl)cc5Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M21 compound treatment 266142.0 17200.0 0.35 269176.0 18100.0 0.38 0.513 0.9992 714 SPBio_002499 CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc2ccc(OC)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M22 compound treatment 2745.0 -246000.0 -4.99 3981.0 -247000.0 -5.15 -7.1694 -0.9999 1000211 SPBio_002500 C[C@@H]1[C@H](O)CC[C@@]2(C)[C@H]1CC[C@@]3(C)[C@H]2[C@H](O)C[C@H]4/C(=C(\CCC=C(C)C)/C(=O)O)/[C@H](C[C@@]43C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M23 mock treatment 249971.0 998.0 0.02 269680.0 18600.0 0.39 0.2887 0.743 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 M24 mock treatment 231772.0 -17200.0 -0.35 258646.0 7590.0 0.16 -0.1348 -0.352 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N01 mock treatment 271857.0 22900.0 0.46 291636.0 40600.0 0.85 0.9258 0.9601 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N02 mock treatment 253667.0 4690.0 0.1 284550.0 33500.0 0.7 0.5607 0.7962 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N03 compound treatment 275251.0 26300.0 0.53 298551.0 47500.0 0.99 1.0764 0.9578 2830 SPBio_002501 Clc1ccc2n(C3CCN(CCCn4c(=O)[nH]c5ccccc45)CC3)c(=O)[nH]c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N04 compound treatment 388055.0 139000.0 2.82 423496.0 172000.0 3.59 4.534 0.9928 1309 SPBio_002502 Cc1cc(C2CCCCC2)n(O)c(=O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N05 compound treatment 305957.0 57000.0 1.16 359967.0 109000.0 2.27 2.4213 0.951 3189434 SPBio_002503 Nc1nc(cs1)/C(=N\OCC(=O)O)/C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)C=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N06 compound treatment 307202.0 58200.0 1.18 323574.0 72500.0 1.51 1.903 0.9926 722 SPBio_002504 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N07 compound treatment 308039.0 59100.0 1.2 336466.0 85400.0 1.78 2.1049 0.9814 3069124 SPBio_002505 CN(C(=O)C)c1c(I)c(NC(=O)C)c(I)c(C(=O)NC2[C@H](O)OC(CO)[C@@H](O)[C@H]2O)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N08 compound treatment 317545.0 68600.0 1.39 275081.0 24000.0 0.5 1.3369 0.9048 1213 SPBio_002506 CNCCc1ccccn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N09 compound treatment 285573.0 36600.0 0.74 345859.0 94800.0 1.98 1.9212 0.9106 3189435 SPBio_002507 C[C@@H](O[C@@H]1[C@H](O)C(CO)O[C@H](O)C1NC(=O)C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N10 compound treatment 195820.0 -53200.0 -1.08 203234.0 -47800.0 -1.0 -1.4664 -0.9992 1000177 SPBio_002508 NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N11 compound treatment 6734.0 -242000.0 -4.91 26304.0 -225000.0 -4.68 -6.7834 -0.9997 2181 SPBio_002509 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3cc(O)c(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N12 compound treatment 272619.0 23600.0 0.48 320043.0 69000.0 1.44 1.3552 0.8945 1000096 SPBio_002510 C1CN2CC(N=C2S1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N13 compound treatment 258524.0 9550.0 0.19 313829.0 62800.0 1.31 1.0616 0.803 1733214 SPBio_002511 Oc1ccc(cc1)C2CC(=O)c3c(O)cc(O)cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N14 compound treatment 295177.0 46200.0 0.94 348286.0 97200.0 2.03 2.0946 0.9386 3068775 SPBio_002512 CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N15 compound treatment 294951.0 46000.0 0.93 324478.0 73400.0 1.53 1.7407 0.9718 895 SPBio_002513 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N16 compound treatment 276931.0 28000.0 0.57 288874.0 37800.0 0.79 0.9579 0.9869 1214 SPBio_002514 CCOC(=O)Nc1c[n+](no1)N2CCOCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N17 compound treatment 276761.0 27800.0 0.56 258021.0 6970.0 0.15 0.5009 0.8611 822 SPBio_002515 CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N18 compound treatment 316456.0 67500.0 1.37 256486.0 5430.0 0.11 1.0474 0.763 1000114 SPBio_002516 CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N19 compound treatment 180985.0 -68000.0 -1.38 158367.0 -92700.0 -1.93 -2.34 -0.9863 1067495 SPBio_002517 [O-][N+](=O)c1cnc(s1)N2CCNC2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N20 compound treatment 250993.0 2020.0 0.04 260950.0 9890.0 0.21 0.1747 0.8313 1365793 SPBio_002518 COc1ccc(CN2CCNCC2)c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N21 compound treatment 291276.0 42300.0 0.86 269073.0 18000.0 0.38 0.8718 0.9313 3069161 SPBio_002519 NCc1ccccc1CC(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)CSc4nnnn4CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N22 compound treatment 320175.0 71200.0 1.44 346907.0 95900.0 2.0 2.4327 0.9873 3103826 SPBio_002520 C/C/1=C\CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N23 mock treatment 256521.0 7550.0 0.15 264656.0 13600.0 0.28 0.3085 0.9582 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 N24 mock treatment 244372.0 -4600.0 -0.09 231347.0 -19700.0 -0.41 -0.3563 -0.8462 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O01 mock treatment 246046.0 -2930.0 -0.06 244343.0 -6710.0 -0.14 -0.1408 -0.9271 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O02 mock treatment 235455.0 -13500.0 -0.27 282614.0 31600.0 0.66 0.2711 0.3806 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O03 compound treatment 227311.0 -21700.0 -0.44 311871.0 60800.0 1.27 0.5853 0.4365 3177204 SPBio_002521 CC(C(O)c1ccc(O)cc1)N2CCC(Cc3ccccc3)CC2.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O04 compound treatment 272817.0 23800.0 0.48 288338.0 37300.0 0.78 0.891 0.974 743 SPBio_002522 CC(C)(C)NCC(O)c1cc(O)cc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O05 compound treatment 200633.0 -48300.0 -0.98 179855.0 -71200.0 -1.48 -1.7418 -0.9798 43 SPBio_002523 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O06 compound treatment 265346.0 16400.0 0.33 310456.0 59400.0 1.24 1.1097 0.8662 3061431 SPBio_002524 OC(C(O)C(=O)O)C(=O)O.Fc1ccc(cc1)C(=O)C2CCN(CCn3c(=O)[nH]c4ccccc4c3=O)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O07 compound treatment 178300.0 -70700.0 -1.43 185214.0 -65800.0 -1.37 -1.983 -0.9998 437 SPBio_002525 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O08 compound treatment 284734.0 35800.0 0.72 288183.0 37100.0 0.77 1.0596 0.9995 907335 SPBio_002526 C[N+]1(C)CCOC(O)(C1)c2ccc(cc2)c3ccc(cc3)C4(O)C[N+](C)(C)CCO4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O09 compound treatment 277187.0 28200.0 0.57 271157.0 20100.0 0.42 0.7006 0.9883 3189181 SPBio_002527 CCOC(=O)[C@@H](CCc1ccccc1)NC(C)C(=O)N2CCC[C@@H]2C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O10 compound treatment 252952.0 3980.0 0.08 287190.0 36100.0 0.75 0.5893 0.7784 3471415 SPBio_002528 NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O11 compound treatment 2713.0 -246000.0 -4.99 2067.0 -249000.0 -5.19 -7.198 -0.9998 1077 SPBio_002529 CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4c(ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O12 compound treatment 265237.0 16300.0 0.33 186593.0 -64500.0 -1.34 -0.7165 -0.5181 3068923 SPBio_002530 NCC[C@H](O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2O)C(O)C1OC3OC(CO)C(O)C(N)C3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O13 compound treatment 288917.0 39900.0 0.81 304680.0 53600.0 1.12 1.3625 0.9875 74 SPBio_002531 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O14 compound treatment 273957.0 25000.0 0.51 261678.0 10600.0 0.22 0.5146 0.9311 3189304 SPBio_002532 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)[C@H](O[C@@H]4O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O15 compound treatment 280788.0 31800.0 0.64 255247.0 4190.0 0.09 0.5178 0.7956 3055 SPBio_002533 NC(=N)NCCN1CCCCCCC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O16 compound treatment 124091.0 -125000.0 -2.53 148312.0 -103000.0 -2.14 -3.3037 -0.9965 3068926 SPBio_002534 CCN(CC)CCOc1ccc(cc1)/C(=C(/Cl)\c2ccccc2)/c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O17 compound treatment 239884.0 -9090.0 -0.18 260709.0 9650.0 0.2 0.0119 0.0437 763 SPBio_002535 CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O18 compound treatment 267401.0 18400.0 0.37 259164.0 8110.0 0.17 0.3836 0.9356 3189305 SPBio_002536 CN1CCCN=C1/C=C/c2cccc(O)c2.OC(=O)c1cc2ccccc2c(Cc3cc4ccccc4c(C(=O)O)c3O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O19 compound treatment 249027.0 53.9 0.0 253228.0 2170.0 0.05 0.0328 0.724 907228 SPBio_002537 CCCCCCC[N+](CC)(CC)CCCCc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O20 compound treatment 213383.0 -35600.0 -0.72 204155.0 -46900.0 -0.98 -1.2011 -0.9889 1041 SPBio_002538 CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O21 compound treatment 195632.0 -53300.0 -1.08 210837.0 -40200.0 -0.84 -1.3571 -0.992 1130 SPBio_002539 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O22 compound treatment 273974.0 25000.0 0.51 293815.0 42800.0 0.89 0.9883 0.9643 3189306 SPBio_002540 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4OC(CO[C@@H]5OC(C)[C@H](O)[C@H](O)C5O)[C@@H](O)[C@@H](O)C4O)cc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O23 mock treatment 266831.0 17900.0 0.36 271414.0 20400.0 0.42 0.5559 0.9969 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 O24 mock treatment 255260.0 6290.0 0.13 248926.0 -2130.0 -0.04 0.0587 0.4353 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P01 mock treatment 275034.0 26100.0 0.53 264421.0 13400.0 0.28 0.5705 0.9552 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P02 mock treatment 276564.0 27600.0 0.56 269209.0 18200.0 0.38 0.6629 0.9818 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P03 compound treatment 298918.0 49900.0 1.01 282261.0 31200.0 0.65 1.1757 0.9771 1000325 SPBio_002541 C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P04 compound treatment 267968.0 19000.0 0.39 238751.0 -12300.0 -0.26 0.091 0.1968 922 SPBio_002542 CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P05 compound treatment 286113.0 37100.0 0.75 264761.0 13700.0 0.29 0.7343 0.9119 3069162 SPBio_002543 CC(C)(CO)[C@H](O)C(=O)NCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P06 compound treatment 281412.0 32400.0 0.66 231479.0 -19600.0 -0.41 0.1766 0.2282 2284 SPBio_002544 C[C@H](Cc1ccccc1)N(C)CC#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P07 compound treatment 307277.0 58300.0 1.18 300053.0 49000.0 1.02 1.5576 0.9973 3189436 SPBio_002545 CO[C@]1(NC(=O)C2SC(=C(C(=O)N)C(=O)O)S2)[C@H]3SCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P08 compound treatment 246236.0 -2740.0 -0.06 265738.0 14700.0 0.31 0.177 0.5695 1020 SPBio_002546 NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(=N)N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P09 compound treatment 309012.0 60000.0 1.22 284834.0 33800.0 0.7 1.3583 0.9661 1534 SPBio_002547 O=C(/C=C/C=C/c1ccc2OCOc2c1)N3CCCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P10 compound treatment 286786.0 37800.0 0.77 254188.0 3130.0 0.07 0.5882 0.7645 196 SPBio_002548 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P11 compound treatment 255268.0 6290.0 0.13 242950.0 -8110.0 -0.17 -0.0292 -0.1378 1537011 SPBio_002549 CN(C)CCC(c1ccc(Br)cc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P12 compound treatment 241341.0 -7630.0 -0.15 217201.0 -33900.0 -0.71 -0.6081 -0.8422 1931603 SPBio_002550 Oc1ccc(cc1)C(=O)N/N=C/c2ccc(o2)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P13 compound treatment 7908.0 -241000.0 -4.89 7851.0 -243000.0 -5.07 -7.0384 -0.9998 2551 SPBio_002551 COc1cc(NC(C)CCCN)c2ncccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P14 compound treatment 278664.0 29700.0 0.6 236062.0 -15000.0 -0.31 0.2047 0.3019 804 SPBio_002552 COc1c(C)c2COC(=O)c2c(O)c1C/C=C(\C)/CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P15 compound treatment 243298.0 -5680.0 -0.12 253284.0 2230.0 0.05 -0.0485 -0.3912 1072 SPBio_002553 CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P16 compound treatment 2382.0 -247000.0 -5.0 2504.0 -249000.0 -5.18 -7.1964 -0.9998 3189565 SPBio_002554 CC[C@@H]1OC(=O)[C@H](C)[C@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@](C)(O)C[C@@H](C)[C@@H]4N[C@H](COCCOC)OC([C@H]4C)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P17 compound treatment 190175.0 -58800.0 -1.19 183498.0 -67600.0 -1.41 -1.8381 -0.9966 3480329 SPBio_002555 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(Cl)c2Cl)C(=O)OC)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P18 compound treatment 269283.0 20300.0 0.41 234984.0 -16100.0 -0.33 0.0544 0.1025 3474312 SPBio_002556 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P19 compound treatment 278485.0 29500.0 0.6 264636.0 13600.0 0.28 0.6231 0.9415 1362 SPBio_002557 COc1c2occc2cc3ccc(=O)oc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P20 compound treatment 237532.0 -11400.0 -0.23 233600.0 -17500.0 -0.36 -0.4212 -0.9764 3060137 SPBio_002558 COc1ccccc1N2CCN(CCCCNC(=O)c3ccc4ccccc4c3)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P21 compound treatment 206602.0 -42400.0 -0.86 189831.0 -61200.0 -1.28 -1.5093 -0.9815 3189437 SPBio_002559 COc1ccc(CC(N)C(=O)N[C@@H]2C(O)[C@@H](O[C@@H]2CO)n3cnc4c(ncnc34)N(C)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P22 compound treatment 238685.0 -10300.0 -0.21 230772.0 -20300.0 -0.42 -0.4463 -0.947 1137095 SPBio_002560 CC(Cc1ccccc1)NCCC(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P23 mock treatment 251577.0 2600.0 0.05 249065.0 -1990.0 -0.04 0.008 0.1192 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2165 P24 mock treatment 243062.0 -5910.0 -0.12 258035.0 6980.0 0.15 0.0181 0.0959 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A01 mock treatment 217137.0 -40800.0 -0.83 227669.0 -33000.0 -0.69 -1.0716 -0.9958 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A02 mock treatment 210184.0 -47800.0 -0.97 236579.0 -24100.0 -0.5 -1.0401 -0.9532 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A03 compound treatment 237281.0 -20700.0 -0.42 266137.0 5450.0 0.11 -0.2162 -0.4978 3189566 SPBio_002561 COc1cc2CC[N+](C)(C)[C@@H]3Cc4ccc(O)c(Oc5cc6[C@H](Cc7cccc(Oc(c1O)c32)c7)N(C)CCc6cc5OC)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A04 compound treatment 252155.0 -5810.0 -0.12 251726.0 -8960.0 -0.19 -0.2153 -0.9752 3187611 SPBio_002562 COc1cc(ccc1c2nc3ncccc3[nH]2)S(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A05 compound treatment 239781.0 -18200.0 -0.37 228929.0 -31800.0 -0.66 -0.7285 -0.9618 907285 SPBio_002563 CC(C)[C@@]1(NC(=O)[C@@H]2C[C@H]3[C@@H](Cc4c[nH]c5cccc3c45)N(C)C2)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A06 compound treatment 228158.0 -29800.0 -0.6 234605.0 -26100.0 -0.54 -0.8115 -0.9986 1254 SPBio_002564 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A07 compound treatment 237004.0 -21000.0 -0.42 241381.0 -19300.0 -0.4 -0.5848 -0.9996 961 SPBio_002565 COc1ccc2[C@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5c(OC)c34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A08 compound treatment 233740.0 -24200.0 -0.49 238017.0 -22700.0 -0.47 -0.6812 -0.9998 3187612 SPBio_002566 CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A09 compound treatment 227456.0 -30500.0 -0.62 258529.0 -2160.0 -0.04 -0.4691 -0.7566 3487467 SPBio_002567 CCOC(=O)Oc1c(OC)cc(cc1OC)C(=O)OC2CC3CN4CCc5c([nH]c6cc(OC)ccc56)C4CC3C(C2OC)C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A10 compound treatment 257846.0 -115.0 0.0 235582.0 -25100.0 -0.52 -0.3715 -0.7103 3069530 SPBio_002568 CC(=O)NC1CCSC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A11 compound treatment 256870.0 -1090.0 -0.02 244211.0 -16500.0 -0.34 -0.2584 -0.7511 1000124 SPBio_002569 CN1C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A12 compound treatment 244426.0 -13500.0 -0.27 248058.0 -12600.0 -0.26 -0.3801 -0.9998 1000240 SPBio_002570 CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A13 compound treatment 232706.0 -25300.0 -0.51 237130.0 -23600.0 -0.49 -0.7091 -0.9998 976 SPBio_002571 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A14 compound treatment 233089.0 -24900.0 -0.5 229023.0 -31700.0 -0.66 -0.823 -0.9912 3187613 SPBio_002572 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)OC2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A15 compound treatment 224182.0 -33800.0 -0.68 261780.0 1090.0 0.02 -0.4682 -0.6833 3189567 SPBio_002573 CCN1C[C@@]2(COC)C3[C@@H](OC)[C@H]4[C@@H]1[C@@]3(C5C[C@@]6(O)[C@H](OC(=O)c7ccccc7)C5[C@]4(OC(=O)C)[C@@H](O)[C@H]6OC)[C@H](C[C@H]2O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A16 compound treatment 253220.0 -4740.0 -0.1 272669.0 12000.0 0.25 0.1085 0.4057 2060360 SPBio_002574 C1CN=C(C1)c2cccnc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A17 compound treatment 233718.0 -24200.0 -0.49 230031.0 -30700.0 -0.64 -0.7992 -0.9916 3141 SPBio_002575 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)/C=C/c6cc(OC)c(OC)c(OC)c6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A18 compound treatment 228659.0 -29300.0 -0.59 254514.0 -6180.0 -0.13 -0.511 -0.8407 3069532 SPBio_002576 C[N+]1(C)C[C@@H](O)C[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A19 compound treatment 213357.0 -44600.0 -0.9 230515.0 -30200.0 -0.63 -1.0839 -0.9842 3068781 SPBio_002577 CC(C)[C@@H]1N2C(=O)[C@](NC(=O)[C@@H]3C[C@H]4[C@@H](Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A20 compound treatment 229502.0 -28500.0 -0.58 255335.0 -5350.0 -0.11 -0.4868 -0.8285 946 SPBio_002578 OCCNC(=O)Cn1ccnc1[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A21 compound treatment 231287.0 -26700.0 -0.54 238495.0 -22200.0 -0.46 -0.7093 -0.997 3189569 SPBio_002579 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1CC4NCCc5cc(OC)c(OC)cc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A22 compound treatment 197970.0 -60000.0 -1.22 234047.0 -26600.0 -0.56 -1.2524 -0.9369 3187614 SPBio_002580 NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)[C@H](O)[C@@H]2N)[C@H](OC3O[C@H](CO)[C@@H](O)[C@@H]3O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A23 mock treatment 205398.0 -52600.0 -1.07 226293.0 -34400.0 -0.72 -1.2602 -0.9814 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 A24 mock treatment 219636.0 -38300.0 -0.78 222408.0 -38300.0 -0.8 -1.1133 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B01 mock treatment 247114.0 -10800.0 -0.22 251694.0 -9000.0 -0.19 -0.288 -0.9968 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B02 mock treatment 266499.0 8540.0 0.17 249298.0 -11400.0 -0.24 -0.0454 -0.1546 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B03 compound treatment 251826.0 -6140.0 -0.12 265079.0 4390.0 0.09 -0.0233 -0.1508 1606 SPBio_002581 NS(=O)(=O)c1cc2c(NC(CSCC=C)NS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B04 compound treatment 279945.0 22000.0 0.45 308888.0 48200.0 1.0 1.0252 0.9332 1412 SPBio_002582 CN(C)CCOC(c1ccc(Cl)cc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B05 compound treatment 264577.0 6620.0 0.13 246048.0 -14600.0 -0.31 -0.1208 -0.3627 1524 SPBio_002583 CC(C)Nc1c(C)n(C)n(c2ccccc2)c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B06 compound treatment 193794.0 -64200.0 -1.3 165184.0 -95500.0 -1.99 -2.3267 -0.9788 3069629 SPBio_002584 CC(=O)/N=c/1\sc(nn1C)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B07 compound treatment 2396.0 -256000.0 -5.18 2689.0 -258000.0 -5.37 -7.4642 -0.9998 883 SPBio_002585 CC(Oc1ccccc1)C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B08 compound treatment 265140.0 7180.0 0.15 252521.0 -8170.0 -0.17 -0.0174 -0.0778 818 SPBio_002586 CCC1(CC)C(=O)NC=CC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B09 compound treatment 180060.0 -77900.0 -1.58 173724.0 -87000.0 -1.81 -2.3978 -0.9977 887 SPBio_002587 COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B10 compound treatment 285798.0 27800.0 0.56 260489.0 -200.0 0.0 0.3961 0.7019 795 SPBio_002588 CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B11 compound treatment 292888.0 34900.0 0.71 263995.0 3310.0 0.07 0.5494 0.7722 745 SPBio_002589 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B12 compound treatment 236173.0 -21800.0 -0.44 251898.0 -8790.0 -0.18 -0.4418 -0.924 1129 SPBio_002590 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B13 compound treatment 275420.0 17500.0 0.35 253188.0 -7500.0 -0.16 0.1398 0.3613 3263 SPBio_002591 CNC(C)(C)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B14 compound treatment 261792.0 3830.0 0.08 243210.0 -17500.0 -0.36 -0.2026 -0.5441 755 SPBio_002592 CC(CN(C)C)CN1c2ccccc2CCc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B15 compound treatment 268471.0 10500.0 0.21 262012.0 1320.0 0.03 0.1702 0.792 3187750 SPBio_002593 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B16 compound treatment 238575.0 -19400.0 -0.39 243079.0 -17600.0 -0.37 -0.5373 -0.9994 1088922 SPBio_002594 CN(C)CCN(Cc1ccc(Cl)cc1)c2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B17 compound treatment 50179.0 -208000.0 -4.21 39477.0 -221000.0 -4.61 -6.2373 -0.999 751 SPBio_002595 COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B18 compound treatment 6131.0 -252000.0 -5.11 5016.0 -256000.0 -5.33 -7.3764 -0.9998 3043753 SPBio_002596 [O-][N+](=O)c1ccc(/C=N/N2CCOC2=O)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B19 compound treatment 263298.0 5340.0 0.11 236444.0 -24200.0 -0.51 -0.2806 -0.5433 1146 SPBio_002597 Nc1ccc(cc1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B20 compound treatment 249624.0 -8340.0 -0.17 245395.0 -15300.0 -0.32 -0.3448 -0.956 2570 SPBio_002598 NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B21 compound treatment 265282.0 7320.0 0.15 233508.0 -27200.0 -0.57 -0.2955 -0.5047 3069577 SPBio_002599 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC(=O)[C@]23C)OC61CCC(C)CO6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B22 compound treatment 32526.0 -225000.0 -4.57 32208.0 -228000.0 -4.76 -6.5974 -0.9998 871 SPBio_002600 Clc1ccc(CSC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B23 mock treatment 235781.0 -22200.0 -0.45 241321.0 -19400.0 -0.4 -0.6033 -0.9985 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 B24 mock treatment 241140.0 -16800.0 -0.34 256429.0 -4260.0 -0.09 -0.3039 -0.8624 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C01 mock treatment 252316.0 -5650.0 -0.11 276513.0 15800.0 0.33 0.1522 0.4361 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C02 mock treatment 272490.0 14500.0 0.29 242687.0 -18000.0 -0.38 -0.0569 -0.1194 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C03 compound treatment 134092.0 -124000.0 -2.51 146831.0 -114000.0 -2.37 -3.4529 -0.9996 1218 SPBio_002601 CCCCNc1ccc(cc1)C(=O)OCCN(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C04 compound treatment 179461.0 -78500.0 -1.59 199837.0 -60900.0 -1.27 -2.0217 -0.9937 1624 SPBio_002602 CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C05 compound treatment 304167.0 46200.0 0.94 298303.0 37600.0 0.78 1.2165 0.9961 1000293 SPBio_002603 C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c5ccco5)C(=O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C06 compound treatment 304267.0 46300.0 0.94 297722.0 37000.0 0.77 1.2093 0.9953 3187615 SPBio_002604 CC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)OC2[C@@]53C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C07 compound treatment 120019.0 -138000.0 -2.8 148018.0 -113000.0 -2.35 -3.6372 -0.9962 3189571 SPBio_002605 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)O[C@]61CCC(C)CN6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C08 compound treatment 271743.0 13800.0 0.28 264384.0 3690.0 0.08 0.252 0.8695 1244 SPBio_002606 C[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C09 compound treatment 60275.0 -198000.0 -4.01 45931.0 -215000.0 -4.47 -5.9975 -0.9985 964 SPBio_002607 CN(C)N=Nc1[nH]cnc1C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C10 compound treatment 264479.0 6520.0 0.13 247705.0 -13000.0 -0.27 -0.0978 -0.325 3187616 SPBio_002608 C/C(=C(\CCOP(=O)(O)O)/SC(=O)c1ccccc1)/N(Cc2cnc(C)nc2N)C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C11 compound treatment 273186.0 15200.0 0.31 250764.0 -9930.0 -0.21 0.072 0.1939 3471597 SPBio_002609 CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C12 compound treatment 251715.0 -6250.0 -0.13 274689.0 14000.0 0.29 0.1167 0.367 3069534 SPBio_002610 CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)CC[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C13 compound treatment 270176.0 12200.0 0.25 257865.0 -2820.0 -0.06 0.1335 0.5245 1092107 SPBio_002611 CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C14 compound treatment 267675.0 9710.0 0.2 241735.0 -19000.0 -0.39 -0.14 -0.3172 3187617 SPBio_002612 CC1OC(C[C@@H](O)[C@@H]1OC2C[C@@H](O)[C@H](OC3C[C@@H](OC(=O)C)[C@H](OC4OC(CO)[C@@H](O)[C@@H](O)[C@@H]4O)C(C)O3)C(C)O2)OC5CC[C@@]6(C)[C@H](CC[C@@]7(C)[C@@]8(O)CC[C@H](C9=CC(=O)OC9)[C@@]8(C)[C@H](O)C[C@]67C)C5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C15 compound treatment 259143.0 1180.0 0.02 241713.0 -19000.0 -0.4 -0.2626 -0.663 1000115 SPBio_002613 COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C16 compound treatment 223025.0 -34900.0 -0.71 252942.0 -7750.0 -0.16 -0.6149 -0.8465 3103678 SPBio_002614 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C17 compound treatment 268285.0 10300.0 0.21 248709.0 -12000.0 -0.25 -0.0285 -0.0874 450 SPBio_002615 COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C18 compound treatment 265560.0 7600.0 0.15 262848.0 2160.0 0.04 0.1407 0.8769 827 SPBio_002616 CCCCC1(COC(=O)CCC(=O)O)C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C19 compound treatment 257065.0 -896.0 -0.02 239137.0 -21600.0 -0.45 -0.3303 -0.7351 1084508 SPBio_002617 COc1ccc2cc3-c4cc(OC)c(OC)cc4CC[n+]3cc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C20 compound treatment 263285.0 5320.0 0.11 257941.0 -2750.0 -0.06 0.0358 0.2933 3069535 SPBio_002618 C(Nc1ncnc2nc[nH]c12)c3ccco3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C21 compound treatment 247889.0 -10100.0 -0.2 206902.0 -53800.0 -1.12 -0.9367 -0.8224 1219467 SPBio_002619 COc1cc2CCC(N)c3cc(=O)c(O)ccc3-c2c(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C22 compound treatment 270592.0 12600.0 0.26 275278.0 14600.0 0.3 0.396 0.9964 3187618 SPBio_002620 CC[C@H](C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C/C=C(\C)/C(O[C@H]4C[C@H](OC)C(O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2)C=C[C@@H]1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C23 mock treatment 224789.0 -33200.0 -0.67 252461.0 -8230.0 -0.17 -0.5967 -0.8599 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 C24 mock treatment 249419.0 -8540.0 -0.17 210207.0 -50500.0 -1.05 -0.8661 -0.8126 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D01 mock treatment 267216.0 9260.0 0.19 227319.0 -33400.0 -0.7 -0.3589 -0.4984 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D02 mock treatment 248712.0 -9250.0 -0.19 232070.0 -28600.0 -0.6 -0.5542 -0.8867 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D03 compound treatment 45441.0 -213000.0 -4.31 33108.0 -228000.0 -4.74 -6.399 -0.9989 706 SPBio_002621 Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D04 compound treatment 270725.0 12800.0 0.26 261765.0 1080.0 0.02 0.1988 0.7655 3472295 SPBio_002622 COc1c(O)cc2C(=O)OC3C(O)C(O)C(CO)OC3c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D05 compound treatment 316844.0 58900.0 1.19 313016.0 52300.0 1.09 1.6149 0.999 3187751 SPBio_002623 CN(N=O)C(=O)NC1[C@@H](O)OC(CO)[C@@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D06 compound treatment 290895.0 32900.0 0.67 287225.0 26500.0 0.55 0.863 0.9956 1446 SPBio_002624 OC(COc1cccc2oc(cc(=O)c12)C(=O)O)COc3cccc4oc(cc(=O)c34)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D07 compound treatment 267757.0 9800.0 0.2 273427.0 12700.0 0.27 0.3281 0.9898 3173081 SPBio_002625 COCCc1ccc(OCC(O)CNC(C)C)cc1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D08 compound treatment 279491.0 21500.0 0.44 258731.0 -1960.0 -0.04 0.2798 0.6382 3187884 SPBio_002626 CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(=O)(O)O[C@@H]4C3OC(=O)CCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D09 compound treatment 276467.0 18500.0 0.38 277792.0 17100.0 0.36 0.5172 0.9997 3187752 SPBio_002627 C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D10 compound treatment 331648.0 73700.0 1.49 313567.0 52900.0 1.1 1.8353 0.9888 3176931 SPBio_002628 NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@@H](c4ccccc4)S(=O)(=O)O)C3=O)C(=O)O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D11 compound treatment 261292.0 3330.0 0.07 275896.0 15200.0 0.32 0.2718 0.839 359 SPBio_002629 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D12 compound treatment 269177.0 11200.0 0.23 273441.0 12800.0 0.27 0.3486 0.997 717 SPBio_002630 OC(=O)c1ccccc1OP(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D13 compound treatment 3194.0 -255000.0 -5.16 3756.0 -257000.0 -5.35 -7.437 -0.9998 689 SPBio_002631 Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C(=O)O)s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D14 compound treatment 265805.0 7840.0 0.16 254154.0 -6540.0 -0.14 0.0162 0.0773 1102 SPBio_002632 CC(C(=O)O)c1ccc(cc1)C(=O)c2cccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D15 compound treatment 282267.0 24300.0 0.49 252679.0 -8010.0 -0.17 0.2304 0.4429 3173859 SPBio_002633 CC(C)CC(=O)OC1C(O[C@@H]2C[C@H]([C@H]3CC[C@]4(CC5CC[C@H]4[C@]3(C)C2)[C@@H](O)C5=C)C(=O)O)OC(CO)C(OS(=O)(=O)O)C1OS(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D16 compound treatment 115989.0 -142000.0 -2.88 264524.0 3830.0 0.08 -1.9787 -0.6872 1254 SPBio_002634 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D17 compound treatment 277467.0 19500.0 0.4 267672.0 6980.0 0.15 0.3825 0.9078 873 SPBio_002635 Nc1nc(=O)c2N(C=O)C(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)CNc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D18 compound treatment 276910.0 18900.0 0.38 236051.0 -24600.0 -0.51 -0.0913 -0.1424 1055 SPBio_002636 CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D19 compound treatment 243726.0 -14200.0 -0.29 264407.0 3720.0 0.08 -0.1493 -0.4996 1402956 SPBio_002637 CC(N)C(O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D20 compound treatment 168811.0 -89200.0 -1.81 129917.0 -131000.0 -2.72 -3.2044 -0.9801 1000139 SPBio_002638 CO[C@]1(NC(=O)C(C(=O)O)c2ccc(O)cc2)[C@H]3OCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D21 compound treatment 3239.0 -255000.0 -5.16 3548.0 -257000.0 -5.36 -7.4394 -0.9998 1531 SPBio_002639 O=c1n([se]c2ccccc12)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D22 compound treatment 255616.0 -2350.0 -0.05 247111.0 -13600.0 -0.28 -0.2336 -0.8145 856 SPBio_002640 Cn1c(=O)n(C)c2nc[nH]c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D23 mock treatment 249762.0 -8200.0 -0.17 248412.0 -12300.0 -0.26 -0.2984 -0.9782 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 D24 mock treatment 233707.0 -24300.0 -0.49 217859.0 -42800.0 -0.89 -0.9786 -0.9606 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E01 mock treatment 242321.0 -15600.0 -0.32 276300.0 15600.0 0.33 0.0058 0.0127 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E02 mock treatment 290250.0 32300.0 0.65 287680.0 27000.0 0.56 0.8605 0.9971 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E03 compound treatment 280596.0 22600.0 0.46 240969.0 -19700.0 -0.41 0.034 0.0552 3180327 SPBio_002641 COc1ccc2[C@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E04 compound treatment 275122.0 17200.0 0.35 260805.0 116.0 0.0 0.2477 0.712 3069536 SPBio_002642 OC[C@H]1OC([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3c(=O)cc(oc23)c4ccc(O)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E05 compound treatment 273525.0 15600.0 0.32 293854.0 33200.0 0.69 0.7117 0.9369 1054667 SPBio_002643 CN1C(CC(O)c2ccccc2)CCCC1CC(O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E06 compound treatment 282998.0 25000.0 0.51 297083.0 36400.0 0.76 0.895 0.981 1001945 SPBio_002644 CN1C[C@@]2(C=C)C3CC4OCC3C1[C@@H]2[C@@]45C(=O)Nc6ccccc65 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E07 compound treatment 265478.0 7520.0 0.15 310935.0 50200.0 1.05 0.8479 0.8016 959 SPBio_002645 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E08 compound treatment 269413.0 11500.0 0.23 296306.0 35600.0 0.74 0.6888 0.886 3187619 SPBio_002646 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)OC61CCC(C)CN6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E09 compound treatment 302387.0 44400.0 0.9 290367.0 29700.0 0.62 1.074 0.9832 3000363 SPBio_002647 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E10 compound treatment 288712.0 30800.0 0.62 284277.0 23600.0 0.49 0.7883 0.9931 3069538 SPBio_002648 CCN1C[C@]2(COC)CC[C@H](OC)[C@]3(C4C[C@H]5[C@H](OC)C4C6(C[C@@H]5OC)OCO[C@@]76[C@@H](O)C32)[C@@H]17 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E11 compound treatment 220231.0 -37700.0 -0.76 290044.0 29400.0 0.61 -0.1084 -0.1107 3061052 SPBio_002649 CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1CC(=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E12 compound treatment 290680.0 32700.0 0.66 301436.0 40700.0 0.85 1.0693 0.9926 1054504 SPBio_002650 COc1c(OCC(O)C(C)(C)O)ccc2c(OC)c3ccoc3nc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E13 compound treatment 277718.0 19800.0 0.4 250788.0 -9900.0 -0.21 0.1374 0.3049 909 SPBio_002651 COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E14 compound treatment 299168.0 41200.0 0.84 283079.0 22400.0 0.47 0.9205 0.9621 3187620 SPBio_002652 C[C@H]1CCC[C@@H](C)N1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E15 compound treatment 290698.0 32700.0 0.66 256510.0 -4180.0 -0.09 0.4077 0.6091 3189572 SPBio_002653 CN1Cc2c3OCOc3ccc2[C@H]4[C@@H](O)Cc5cc6OCOc6cc5[C@H]41 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E16 compound treatment 301687.0 43700.0 0.89 296928.0 36200.0 0.75 1.1607 0.9968 1540789 SPBio_002654 COc1cc(=O)n(C)c2c(OCC(O)C(C)(C)O)cccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E17 compound treatment 305916.0 48000.0 0.97 304189.0 43500.0 0.91 1.3282 0.9994 1202 SPBio_002655 COc1ccc2CN(C)CC[C@]34C=C[C@H](O)C[C@@H]4Oc1c23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E18 compound treatment 292905.0 34900.0 0.71 269180.0 8490.0 0.18 0.626 0.8573 1054505 SPBio_002656 COc1ccc2c(OC)c3ccoc3nc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E19 compound treatment 299742.0 41800.0 0.85 285326.0 24600.0 0.51 0.9619 0.9712 1220 SPBio_002657 CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E20 compound treatment 298103.0 40100.0 0.81 278431.0 17700.0 0.37 0.8368 0.9362 852250 SPBio_002658 C1CCC(NC1)c2cccnc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E21 compound treatment 251858.0 -6100.0 -0.12 259244.0 -1450.0 -0.03 -0.1088 -0.8542 3173993 SPBio_002659 O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E22 compound treatment 256932.0 -1030.0 -0.02 273078.0 12400.0 0.26 0.1678 0.6478 193 SPBio_002660 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E23 mock treatment 251219.0 -6740.0 -0.14 256736.0 -3950.0 -0.08 -0.1549 -0.9706 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 E24 mock treatment 241929.0 -16000.0 -0.33 223107.0 -37600.0 -0.78 -0.7834 -0.9242 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F01 mock treatment 264070.0 6110.0 0.12 256364.0 -4330.0 -0.09 0.0239 0.1558 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F02 mock treatment 265414.0 7450.0 0.15 298585.0 37900.0 0.79 0.6651 0.8274 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F03 compound treatment 269340.0 11400.0 0.23 262179.0 1490.0 0.03 0.1851 0.7951 3069579 SPBio_002661 NC(=O)c1ccc[n+](c1)[C@H]2O[C@@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@H](C(O)[C@H]3O)n4cnc5c(N)ncnc45)C(O)[C@H]2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F04 compound treatment 2455.0 -256000.0 -5.18 3095.0 -258000.0 -5.37 -7.4574 -0.9998 691 SPBio_002662 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)c4ccccc4)C(=O)N2C1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F05 compound treatment 127206.0 -131000.0 -2.65 95306.0 -165000.0 -3.45 -4.3107 -0.9916 799 SPBio_002663 Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F06 compound treatment 317806.0 59800.0 1.21 263929.0 3240.0 0.07 0.9056 0.7453 1303 SPBio_002664 C[N+]1(CCC2CC1)CC2OC(=O)C(O)(c3ccccc3)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F07 compound treatment 273366.0 15400.0 0.31 300856.0 40200.0 0.84 0.8125 0.9097 3187753 SPBio_002665 C[C@H]1C[C@H]2[C@@H]3CC[C@H](C(=O)C)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)CCC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F08 compound treatment 41195.0 -217000.0 -4.39 41950.0 -219000.0 -4.56 -6.3296 -0.9998 1529 SPBio_002666 COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F09 compound treatment 313815.0 55900.0 1.13 320057.0 59400.0 1.24 1.6752 0.999 3187754 SPBio_002667 CNCC(O)C(O)C(O)C(O)CO.Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F10 compound treatment 265150.0 7190.0 0.15 317205.0 56500.0 1.18 0.9356 0.7886 1114 SPBio_002668 NS(=O)(=O)c1cc2c(N=C(CSCc3ccccc3)NS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F11 compound treatment 9785.0 -248000.0 -5.03 6904.0 -254000.0 -5.29 -7.2962 -0.9997 3187755 SPBio_002669 CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C/C=C/C=C/[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F12 compound treatment 276786.0 18800.0 0.38 282262.0 21600.0 0.45 0.5877 0.9967 1000 SPBio_002670 NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F13 compound treatment 259465.0 1500.0 0.03 299472.0 38800.0 0.81 0.5929 0.7333 3069580 SPBio_002671 C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F14 compound treatment 281423.0 23500.0 0.48 279450.0 18800.0 0.39 0.6127 0.9952 1052436 SPBio_002672 CCN(CC)CCc1nc(no1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F15 compound treatment 59298.0 -199000.0 -4.03 40694.0 -220000.0 -4.58 -6.0886 -0.9979 3069581 SPBio_002673 Cn1nnnc1SCC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@H](O)c4ccccc4)C3=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F16 compound treatment 320740.0 62800.0 1.27 274673.0 14000.0 0.29 1.1059 0.8471 1397 SPBio_002674 CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F17 compound treatment 31343.0 -227000.0 -4.59 108488.0 -152000.0 -3.17 -5.4907 -0.9836 3187756 SPBio_002675 CC[C@]1(CC[C@@H](O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@H](O3)[C@@H](C)[C@@H](OC)C(C)C(=O)O)O2)[C@@H]4O[C@H](C[C@@H]4C)[C@H]5O[C@@](O)(CO)[C@H](C)C[C@@H]5C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F18 compound treatment 10796.0 -247000.0 -5.01 6651.0 -254000.0 -5.29 -7.2854 -0.9996 3187885 SPBio_002676 CC[C@H]([C@H]1O[C@@](CC)(C[C@@H]1C)[C@H]2CC[C@](O)(CC)[C@H](C)O2)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F19 compound treatment 263346.0 5390.0 0.11 317782.0 57100.0 1.19 0.9182 0.7688 4338 SPBio_002677 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F20 compound treatment 251935.0 -6030.0 -0.12 261133.0 444.0 0.01 -0.0798 -0.6517 1519 SPBio_002678 CC1(C)OC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F21 compound treatment 263607.0 5650.0 0.11 262760.0 2070.0 0.04 0.1114 0.9111 3069582 SPBio_002679 C[C@@]1(O)CCOC(=O)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F22 compound treatment 233185.0 -24800.0 -0.5 262802.0 2110.0 0.04 -0.324 -0.6427 852 SPBio_002680 CCOc1ccc(Cc2nccc3cc(OCC)c(OCC)cc23)cc1OCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F23 mock treatment 244098.0 -13900.0 -0.28 264312.0 3620.0 0.08 -0.1454 -0.4995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 F24 mock treatment 234554.0 -23400.0 -0.47 243728.0 -17000.0 -0.35 -0.5854 -0.9895 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G01 mock treatment 229752.0 -28200.0 -0.57 252115.0 -8570.0 -0.18 -0.5307 -0.8858 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G02 mock treatment 285465.0 27500.0 0.56 270010.0 9320.0 0.19 0.5316 0.9003 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G03 compound treatment 249792.0 -8170.0 -0.17 258076.0 -2610.0 -0.05 -0.1556 -0.8926 1000946 SPBio_002681 COc1ccc(CC2N(C)CCc3cc(OC)c(OC)cc23)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G04 compound treatment 249979.0 -7980.0 -0.16 276188.0 15500.0 0.32 0.1139 0.3154 3129 SPBio_002682 CC(=O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@@]4(C)[C@@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G05 compound treatment 274169.0 16200.0 0.33 277072.0 16400.0 0.34 0.4737 0.9998 3054974 SPBio_002683 COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G06 compound treatment 276179.0 18200.0 0.37 283120.0 22400.0 0.47 0.5916 0.9932 1025381 SPBio_002684 COc1ccc2CC3N(CCc4cc5OCOc5cc34)Cc2c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G07 compound treatment 249769.0 -8190.0 -0.17 279239.0 18500.0 0.39 0.1558 0.3705 3189573 SPBio_002685 COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)C3C[C@@H]21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G08 compound treatment 284246.0 26300.0 0.53 281523.0 20800.0 0.43 0.6837 0.9948 3187622 SPBio_002686 CCN1C[C@]2(C)CC[C@H](OC)[C@@]34C2[C@H](OC(=O)C)C5(OCO[C@]65C[C@H](OC)C7C[C@]4(O)C6[C@H]7OC)[C@@H]13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G09 compound treatment 304627.0 46700.0 0.95 285289.0 24600.0 0.51 1.0313 0.9585 915 SPBio_002687 OC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G10 compound treatment 286230.0 28300.0 0.57 281199.0 20500.0 0.43 0.7074 0.9895 1182082 SPBio_002688 Cn1c(cc(=O)c2ccccc12)c3ccc4OCOc4c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G11 compound treatment 288587.0 30600.0 0.62 257712.0 -2980.0 -0.06 0.3952 0.6333 1056553 SPBio_002689 CN1CCC23C4Nc5ccccc5C3(CCN4C)C1Nc6ccccc62 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G12 compound treatment 267657.0 9700.0 0.2 288578.0 27900.0 0.58 0.5498 0.8964 3069539 SPBio_002690 CN1CCC2=C[C@@H](O)[C@@H]3OC(=O)c4cc5OCOc5cc4C3[C@@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G13 compound treatment 278783.0 20800.0 0.42 275387.0 14700.0 0.31 0.515 0.9876 3069519 SPBio_002691 COc1ccc(cc1OC)C(=O)O[C@@H]2C[C@@H]3CC[C@H](C2)N3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G14 compound treatment 278458.0 20500.0 0.42 273603.0 12900.0 0.27 0.4841 0.9779 3187623 SPBio_002692 CC=C(C)C(=O)OC1[C@H](OC(=O)C)C2(CO)[C@H](O)C[C@]3(C)C(=CCC4C5(C)CCC(OC6OC([C@H](O[C@H]7OC(CO)[C@H](O)[C@H](O)C7O)[C@H](O)C6O[C@H]8OC(CO)[C@H](O)[C@H](O)C8O)C(=O)O)[C@](C)(CO)C5CCC43C)C2CC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G15 compound treatment 227025.0 -30900.0 -0.63 253018.0 -7670.0 -0.16 -0.5565 -0.8598 2060325 SPBio_002693 COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(c34)-c2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G16 compound treatment 78055.0 -180000.0 -3.65 149438.0 -111000.0 -2.32 -4.2178 -0.976 829 SPBio_002694 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G17 compound treatment 286282.0 28300.0 0.57 268994.0 8300.0 0.17 0.5283 0.8811 1076 SPBio_002695 Cc1cccc(C)c1NC2=NCCCS2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G18 compound treatment 334190.0 76200.0 1.55 326715.0 66000.0 1.38 2.0654 0.9983 1115322 SPBio_002696 COc1ccn(C)c(=O)c1C#N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G19 compound treatment 273200.0 15200.0 0.31 262400.0 1710.0 0.04 0.2437 0.7835 3179848 SPBio_002697 C/C=C\1/CC(=C)[C@@](C)(O)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G20 compound treatment 257033.0 -928.0 -0.02 269105.0 8420.0 0.18 0.1107 0.6276 3069540 SPBio_002698 CCN1C[C@]2(COC)CC[C@H](O)[C@]3(C4C[C@H]5C(OC)C4[C@](O)(C[C@H]5OC)C6(O)C(OC)C32)[C@H]16 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G21 compound treatment 206854.0 -51100.0 -1.04 218937.0 -41800.0 -0.87 -1.3477 -0.9962 1737132 SPBio_002699 COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c2c34)cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G22 compound treatment 270545.0 12600.0 0.26 266674.0 5980.0 0.12 0.2686 0.9458 3187624 SPBio_002700 C/C=C\1/C[N@@+]2(C)CCC34[C@@H]2C[C@@H]1C(=C4Nc5ccccc53)C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G23 mock treatment 263083.0 5120.0 0.1 273407.0 12700.0 0.26 0.2608 0.9164 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 G24 mock treatment 246694.0 -11300.0 -0.23 261102.0 413.0 0.01 -0.1554 -0.68 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H01 mock treatment 264921.0 6960.0 0.14 263707.0 3020.0 0.06 0.1442 0.9337 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H02 mock treatment 280942.0 23000.0 0.47 280754.0 20100.0 0.42 0.625 0.9985 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H03 compound treatment 306028.0 48100.0 0.97 285903.0 25200.0 0.53 1.0605 0.958 3480633 SPBio_002701 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H04 compound treatment 283338.0 25400.0 0.51 302827.0 42100.0 0.88 0.9845 0.9676 1452 SPBio_002702 CCCCN(CCCC)CCCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H05 compound treatment 298242.0 40300.0 0.82 330211.0 69500.0 1.45 1.6016 0.9632 1404 SPBio_002703 Nc1ccc(N=Nc2ccccc2)c(N)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H06 compound treatment 312854.0 54900.0 1.11 312537.0 51800.0 1.08 1.5507 0.9999 1189 SPBio_002704 CO[C@]1(NC(=O)Cc2cccs2)[C@H]3SCC(=C(N3C1=O)C(=O)O)COC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H07 compound treatment 2765.0 -255000.0 -5.17 2763.0 -258000.0 -5.37 -7.4578 -0.9998 1451 SPBio_002705 CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H08 compound treatment 253248.0 -4710.0 -0.1 309208.0 48500.0 1.01 0.6472 0.6374 1000080 SPBio_002706 ClCCNP1(=O)OCCCN1CCCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H09 compound treatment 314783.0 56800.0 1.15 296386.0 35700.0 0.74 1.3404 0.9776 1438 SPBio_002707 CC(C(=O)O)c1cccc(Oc2ccccc2)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H10 compound treatment 2506.0 -255000.0 -5.18 2584.0 -258000.0 -5.38 -7.4641 -0.9998 3187886 SPBio_002708 CO[C@@H]1[C@H](OC(=O)N)C(O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H11 compound treatment 2409.0 -256000.0 -5.18 3146.0 -258000.0 -5.37 -7.4573 -0.9998 963 SPBio_002709 CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4)C(=O)C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H12 compound treatment 296276.0 38300.0 0.78 296973.0 36300.0 0.76 1.0838 0.9999 1232 SPBio_002710 OC1=C(O)C(=O)C(=C(O)C1=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H13 compound treatment 50373.0 -208000.0 -4.21 34655.0 -226000.0 -4.71 -6.3055 -0.9984 1138 SPBio_002711 CC/C(=C(/CC)\c1ccc(O)cc1)/c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H14 compound treatment 296760.0 38800.0 0.79 303727.0 43000.0 0.9 1.1902 0.9979 1029 SPBio_002712 CC(C(=O)O)c1ccc(cc1)N2Cc3ccccc3C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H15 compound treatment 254966.0 -3000.0 -0.06 247777.0 -12900.0 -0.27 -0.2331 -0.8454 3057880 SPBio_002713 COc1ccc(cc1)C(=C(c2ccc(OC)cc2)c3ccc(OC)cc3)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H16 compound treatment 310592.0 52600.0 1.07 299769.0 39100.0 0.81 1.3302 0.9911 1276 SPBio_002714 CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]3(C)[C@@H]2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O)OC(=O)CCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H17 compound treatment 261129.0 3170.0 0.06 286248.0 25600.0 0.53 0.4219 0.7867 3187757 SPBio_002715 NCC1OC(OC2C(N)CC(N)C(O)C2O[C@@H]3O[C@H](CO)[C@H](O)C3O)C(N)C(O)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H18 compound treatment 277596.0 19600.0 0.4 276759.0 16100.0 0.33 0.5182 0.9963 3187887 SPBio_002716 CC(CN(C(=O)C)c1c(I)cc(I)c(N)c1I)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H19 compound treatment 306942.0 49000.0 0.99 273311.0 12600.0 0.26 0.8881 0.8646 1094620 SPBio_002717 CC(C[N+](C)(C)C)OC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H20 compound treatment 255004.0 -2960.0 -0.06 285163.0 24500.0 0.51 0.3181 0.6197 1670 SPBio_002718 Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H21 compound treatment 276167.0 18200.0 0.37 277091.0 16400.0 0.34 0.5026 0.9993 1246 SPBio_002719 CC[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H22 compound treatment 266439.0 8480.0 0.17 257340.0 -3350.0 -0.07 0.0722 0.3892 727 SPBio_002720 CCN(CC)C(C)CN1c2ccccc2Sc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H23 mock treatment 277478.0 19500.0 0.4 260077.0 -612.0 -0.01 0.2708 0.684 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 H24 mock treatment 263540.0 5580.0 0.11 306452.0 45800.0 0.95 0.7541 0.7855 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I01 mock treatment 288554.0 30600.0 0.62 261840.0 1150.0 0.02 0.4555 0.7339 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I02 mock treatment 292944.0 35000.0 0.71 295736.0 35000.0 0.73 1.0178 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I03 compound treatment 216028.0 -41900.0 -0.85 226440.0 -34200.0 -0.71 -1.1056 -0.9962 3069520 SPBio_002721 COc1ccc2CC3N(CCc4cc(OC)c(O)cc34)Cc2c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I04 compound treatment 260451.0 2490.0 0.05 304139.0 43400.0 0.91 0.6758 0.7454 3069541 SPBio_002722 C[C@H]1[C@H]2[C@H](OC1=O)[C@H]3C(=CC(=O)C3=C(C)C[C@@H]2O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I05 compound treatment 288034.0 30100.0 0.61 312783.0 52100.0 1.09 1.1985 0.9628 3069521 SPBio_002723 CCC1[C@@H](O)N2C3C[C@@]45[C@H](O)C3C1CC2[C@@H]5N(C)c6ccccc64 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I06 compound treatment 300240.0 42300.0 0.86 312628.0 51900.0 1.08 1.3712 0.9933 3187625 SPBio_002724 CC[N+]1(C)C2CCC1CC(C2)OC(=O)[C@H]3CCC(C(=O)OC4CC5CCC(C4)[N+]5(C)CC)(c6ccccc6)c7ccccc37 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I07 compound treatment 296171.0 38200.0 0.77 323069.0 62400.0 1.3 1.4667 0.9694 1539 SPBio_002725 C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I08 compound treatment 285828.0 27900.0 0.56 312176.0 51500.0 1.07 1.1579 0.9552 3173628 SPBio_002726 CN1C(C)(C)CCCC1(C)C.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I09 compound treatment 320181.0 62200.0 1.26 328726.0 68000.0 1.42 1.8942 0.9983 3069522 SPBio_002727 COc1cc(/C=C/C(=O)N2CCC=CC2=O)cc(OC)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I10 compound treatment 271324.0 13400.0 0.27 293244.0 32600.0 0.68 0.6711 0.919 3069542 SPBio_002728 COC(C)C(O)(C(C)C)C(=O)OCC1=CCN2CC[C@H](O)[C@H]21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I11 compound treatment 271151.0 13200.0 0.27 294323.0 33600.0 0.7 0.6845 0.9127 3100 SPBio_002729 COc1c2OCOc2cc3CCN(C)Cc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I12 compound treatment 25969.0 -232000.0 -4.7 38418.0 -222000.0 -4.63 -6.5999 -1.0 3487155 SPBio_002730 C1CNC2C(C1)C3CCC2C4N3CCc5c4[nH]c6ccccc56 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I13 compound treatment 302145.0 44200.0 0.9 277647.0 17000.0 0.35 0.8832 0.9172 3189574 SPBio_002731 O[C@H]([C@@H]1CC2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I14 compound treatment 298787.0 40800.0 0.83 269183.0 8490.0 0.18 0.7104 0.8393 3069543 SPBio_002732 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H](C32)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I15 compound treatment 266707.0 8750.0 0.18 299055.0 38400.0 0.8 0.6905 0.8435 1039 SPBio_002733 CC[C@]1(CCCN2CCc3c4[C@@H]21)CC(=O)n4c5ccccc35 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I16 compound treatment 289715.0 31800.0 0.64 302897.0 42200.0 0.88 1.077 0.9882 3187744 SPBio_002734 CCN1C[C@]2(C)CC[C@H](O)C3(C4C[C@H]5C(O)C4[C@](O)(C[C@@H]5OC)C6CC32)[C@H]61 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I17 compound treatment 239703.0 -18300.0 -0.37 294778.0 34100.0 0.71 0.2404 0.3002 3069523 SPBio_002735 O[C@@H]([C@H]1CC2CCN1C[C@H]2C=C)c3ccnc4ccccc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I18 compound treatment 282544.0 24600.0 0.5 288819.0 28100.0 0.59 0.7668 0.9967 3187745 SPBio_002736 C[C@@]12CC[C@H]3[C@@H](CCc4cc(OS(=O)(=O)O)ccc34)[C@@H]2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I19 compound treatment 207407.0 -50600.0 -1.02 315094.0 54400.0 1.13 0.0767 0.0502 3189575 SPBio_002737 N[C@H](CCONC(=N)N)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I20 compound treatment 289843.0 31900.0 0.65 303365.0 42700.0 0.89 1.0857 0.9877 3069544 SPBio_002738 CO[C@@H]1C=C2CCN(C)[C@@H]2C3[C@H]1OC(=O)c4cc5OCOc5cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I21 compound treatment 252255.0 -5710.0 -0.12 275282.0 14600.0 0.3 0.1332 0.4094 1530 SPBio_002739 COc1ccc2c3CCN=C(C)c3[nH]c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I22 compound treatment 252769.0 -5190.0 -0.11 265775.0 5090.0 0.11 5.0E-4 0.0033 3187746 SPBio_002740 CCN1C[C@]2(C)CC[C@H](O)C3(C2CC4[C@H]13)C5C[C@H](O)C6C[C@]45[C@H](O)C6=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I23 mock treatment 231650.0 -26300.0 -0.53 271456.0 10800.0 0.22 -0.2186 -0.3777 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 I24 mock treatment 249688.0 -8270.0 -0.17 283870.0 23200.0 0.48 0.2229 0.436 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J01 mock treatment 257010.0 -951.0 -0.02 268441.0 7750.0 0.16 0.1006 0.6183 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J02 mock treatment 278595.0 20600.0 0.42 289907.0 29200.0 0.61 0.7262 0.9832 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J03 compound treatment 278544.0 20600.0 0.42 294274.0 33600.0 0.7 0.7898 0.9695 1429 SPBio_002741 CCCCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J04 compound treatment 311066.0 53100.0 1.08 293662.0 33000.0 0.69 1.247 0.9764 3187888 SPBio_002742 O=C1OC2(C[C@H]3C=CC2=C1)[C@H]4CCCCN34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J05 compound treatment 262090.0 4130.0 0.08 289949.0 29300.0 0.61 0.4902 0.7967 867 SPBio_002743 Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J06 compound treatment 50130.0 -208000.0 -4.21 343154.0 82500.0 1.72 -1.7645 -0.3878 3044756 SPBio_002744 CC(CN(C)C)CN1c2ccccc2Sc3ccccc13.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J07 compound treatment 334626.0 76700.0 1.55 334081.0 73400.0 1.53 2.1801 1.0 1001 SPBio_002745 CN(C)CCOC(=O)COc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J08 compound treatment 67177.0 -191000.0 -3.87 15955.0 -245000.0 -5.1 -6.3401 -0.9907 3187889 SPBio_002746 CCOc1ccc2ccccc2c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J09 compound treatment 166261.0 -91700.0 -1.86 70205.0 -190000.0 -3.97 -4.1206 -0.9403 3069584 SPBio_002747 [O-][N+](=O)c1ccc(/C=N/N2CC(CN3CCOCC3)OC2=O)o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J10 compound treatment 291137.0 33200.0 0.67 328504.0 67800.0 1.41 1.4746 0.9424 1057 SPBio_002748 OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J11 compound treatment 281745.0 23800.0 0.48 266843.0 6150.0 0.13 0.4316 0.8651 837 SPBio_002749 CCOc1ccc2NC(C)(C)C=C(C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J12 compound treatment 261057.0 3100.0 0.06 318128.0 57400.0 1.2 0.8905 0.7432 3069693 SPBio_002750 CN(C)CCCO[C@H]1[C@H](OC2OC(C)(C)O[C@@H]12)C(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J13 compound treatment 273313.0 15400.0 0.31 288576.0 27900.0 0.58 0.6309 0.9572 2575 SPBio_002751 CCS(=O)(=O)CCn1c(C)ncc1[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J14 compound treatment 263967.0 6010.0 0.12 272075.0 11400.0 0.24 0.2538 0.952 2710 SPBio_002752 COc1ccc2[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]4(O)C#C)[C@@H]3CCc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J15 compound treatment 297363.0 39400.0 0.8 299677.0 39000.0 0.81 1.1392 1.0 3187758 SPBio_002753 NC(=N)NCC1COC2(CCCCC2)O1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J16 compound treatment 264849.0 6890.0 0.14 260690.0 0.984 0.0 0.0988 0.7072 3452 SPBio_002754 CC(C)(C)NC[C@H](O)COc1cccc2C(=O)CCCc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J17 compound treatment 191671.0 -66300.0 -1.34 200187.0 -60500.0 -1.26 -1.8415 -0.9995 3060003 SPBio_002755 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](O)C3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J18 compound treatment 317573.0 59600.0 1.21 289529.0 28800.0 0.6 1.2794 0.948 3487254 SPBio_002756 CC(=O)N(CC(O)CN(C(=O)C)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I)c2c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c2I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J19 compound treatment 165049.0 -92900.0 -1.88 152541.0 -108000.0 -2.25 -2.925 -0.996 1094 SPBio_002757 COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J20 compound treatment 269248.0 11300.0 0.23 276101.0 15400.0 0.32 0.3888 0.9862 3069696 SPBio_002758 CN(C)[C@H]1C2CC3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)NCN4CCCC4)C(=O)c5c(O)cccc5[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J21 compound treatment 273526.0 15600.0 0.32 285129.0 24400.0 0.51 0.5832 0.9735 888 SPBio_002759 CC(C)[N+](C)(CCC(C(=O)N)(c1ccccc1)c2ccccc2)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J22 compound treatment 281130.0 23200.0 0.47 271262.0 10600.0 0.22 0.4879 0.9404 1405 SPBio_002760 C[C@@]12CC[C@H]3C(=CCc4cc(O)ccc34)[C@@H]2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J23 mock treatment 254203.0 -3760.0 -0.08 261550.0 861.0 0.02 -0.0412 -0.5262 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 J24 mock treatment 259452.0 1490.0 0.03 248335.0 -12400.0 -0.26 -0.1606 -0.6198 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K01 mock treatment 244840.0 -13100.0 -0.27 243417.0 -17300.0 -0.36 -0.4425 -0.9889 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K02 mock treatment 300393.0 42400.0 0.86 287249.0 26600.0 0.55 0.9995 0.9772 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K03 compound treatment 276534.0 18600.0 0.38 298027.0 37300.0 0.78 0.8163 0.9445 1578 SPBio_002761 CC1=NCCc2c1[nH]c3cc(O)ccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K04 compound treatment 296341.0 38400.0 0.78 296721.0 36000.0 0.75 1.081 0.9998 3187747 SPBio_002762 COc1cc(ccc1O)C(=O)OC2CC3CCC(C2)N3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K05 compound treatment 326383.0 68400.0 1.39 304738.0 44000.0 0.92 1.6297 0.9799 1043296 SPBio_002763 Cc1nccc2c3ccc(O)cc3[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K06 compound treatment 268251.0 10300.0 0.21 316457.0 55800.0 1.16 0.969 0.8209 3187748 SPBio_002764 CC(=O)O[C@H]1C2[C@]3([C@H]4[C@@H]5[C@@H](O)[C@@H]1C(=C)CC52CC6C37)[C@H](OC(=O)C)[C@H](C[C@@]7(C)CN46)OC(=O)c8ccccc8 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K07 compound treatment 310172.0 52200.0 1.06 318574.0 57900.0 1.21 1.6012 0.9979 297849 SPBio_002765 COc1ccc2c(c1)[nH]c3c(C)nccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K08 compound treatment 289377.0 31400.0 0.64 257422.0 -3270.0 -0.07 0.4022 0.628 1047 SPBio_002766 CN(C)CCCN1c2ccccc2Sc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K09 compound treatment 5474.0 -252000.0 -5.12 4831.0 -256000.0 -5.33 -7.3885 -0.9998 2057 SPBio_002767 Cc1c2[nH]c3ccccc3c2c(C)c4cnccc14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K10 compound treatment 190552.0 -67400.0 -1.37 114258.0 -146000.0 -3.05 -3.1234 -0.9344 1177 SPBio_002768 Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K11 compound treatment 155657.0 -102000.0 -2.07 121837.0 -139000.0 -2.89 -3.512 -0.9867 3069524 SPBio_002769 O=C1C=CC(=O)c2c1ccc3c2ccc4ccccc43 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K12 compound treatment 292207.0 34200.0 0.69 266386.0 5700.0 0.12 0.5748 0.8161 1463 SPBio_002770 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K13 compound treatment 309450.0 51500.0 1.04 323224.0 62500.0 1.3 1.6593 0.994 3189576 SPBio_002771 CN(CCCCCCCCCCN(C)C(=O)Oc1ccccc1[N+](C)(C)C)C(=O)Oc2ccccc2[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K14 compound treatment 312736.0 54800.0 1.11 298669.0 38000.0 0.79 1.3447 0.9862 1424515 SPBio_002772 CCN1C(=O)NC(C1=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K15 compound treatment 321762.0 63800.0 1.29 282164.0 21500.0 0.45 1.2309 0.8994 1494 SPBio_002773 C1CN(CCN1)c2ccc3ccccc3n2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K16 compound treatment 281968.0 24000.0 0.49 277918.0 17200.0 0.36 0.5979 0.9888 3069570 SPBio_002774 C[C@@]12CCC3[C@@H](CC[C@@H]4C[C@H](O)CC[C@@]43C)[C@@H]2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K17 compound treatment 277716.0 19800.0 0.4 314996.0 54300.0 1.13 1.0832 0.9025 3069525 SPBio_002775 C1CCN2C[C@@H]3C[C@H](CN4CCCC[C@H]34)[C@@H]2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K18 compound treatment 269505.0 11500.0 0.23 351865.0 91200.0 1.9 1.5086 0.7883 1444 SPBio_002776 C1CN=C(N1)C2CCCc3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K19 compound treatment 276896.0 18900.0 0.38 300073.0 39400.0 0.82 0.8516 0.9401 3043 SPBio_002777 C[C@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)C)C(=O)COC(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K20 compound treatment 128552.0 -129000.0 -2.62 101072.0 -160000.0 -3.33 -4.2064 -0.9931 1070 SPBio_002778 CCC(C(CC)c1ccc(O)cc1)c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K21 compound treatment 287685.0 29700.0 0.6 288451.0 27800.0 0.58 0.8351 0.9998 1035065 SPBio_002779 Cc1nccc2c3ccccc3[nH]c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K22 compound treatment 305011.0 47100.0 0.95 323991.0 63300.0 1.32 1.607 0.9874 1000312 SPBio_002780 CO[C@]1(NC(=O)CSCC#N)[C@H]2SCC(=C(N2C1=O)C(=O)O)CSc3nnnn3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K23 mock treatment 301236.0 43300.0 0.88 267320.0 6630.0 0.14 0.718 0.8085 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 K24 mock treatment 239565.0 -18400.0 -0.37 264579.0 3890.0 0.08 -0.2064 -0.5408 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L01 mock treatment 274628.0 16700.0 0.34 253556.0 -7130.0 -0.15 0.1338 0.3626 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L02 mock treatment 292442.0 34500.0 0.7 249592.0 -11100.0 -0.23 0.3308 0.4493 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L03 compound treatment 278198.0 20200.0 0.41 297740.0 37100.0 0.77 0.8359 0.9563 3187759 SPBio_002781 CCC(=O)OCC(=O)C1(OC(=O)CC)[C@H](C)C[C@H]2[C@@H]3[C@H](Cl)CC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L04 compound treatment 3566.0 -254000.0 -5.16 2699.0 -258000.0 -5.37 -7.4473 -0.9998 712 SPBio_002782 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSc3ccncc3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L05 compound treatment 364023.0 106000.0 2.15 340440.0 79800.0 1.66 2.6952 0.9919 1499 SPBio_002783 Cc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L06 compound treatment 2594.0 -255000.0 -5.18 3078.0 -258000.0 -5.37 -7.4556 -0.9998 3187892 SPBio_002784 C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=C(C(=O)N)C(=O)C3(O)C(=C2C(=O)c4c(O)cccc14)O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L07 compound treatment 310021.0 52100.0 1.06 293812.0 33100.0 0.69 1.2342 0.9788 3069624 SPBio_002785 CC[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]2CC[C@@]1(O)C#C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L08 compound treatment 338315.0 80400.0 1.63 249424.0 -11300.0 -0.23 0.9859 0.5991 1000323 SPBio_002786 N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L09 compound treatment 277419.0 19500.0 0.39 320184.0 59500.0 1.24 1.1554 0.8883 3187760 SPBio_002787 CC(=O)OCC(=O)[C@]12OC(C)(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@@]31C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L10 compound treatment 2390.0 -256000.0 -5.18 2720.0 -258000.0 -5.37 -7.4638 -0.9998 3187893 SPBio_002788 CC[C@H]1OC(=O)[C@H](C)[C@@H](OC2CC(C)(OC)C(O)C(C)O2)[C@H](C)[C@@H](OC3OC(C)CC(C3O)N(C)C)[C@](C)(O)C[C@@H](C)/C(=N\OCOCCOC)/[C@H](C)[C@@H](O)[C@]1(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L11 compound treatment 250461.0 -7500.0 -0.15 199414.0 -61300.0 -1.28 -1.0102 -0.7858 934 SPBio_002789 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L12 compound treatment 322893.0 64900.0 1.32 279018.0 18300.0 0.38 1.2008 0.8761 1000270 SPBio_002790 CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L13 compound treatment 6018.0 -252000.0 -5.11 11180.0 -250000.0 -5.2 -7.2872 -1.0 896 SPBio_002791 COc1ccccc1OCC(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L14 compound treatment 280597.0 22600.0 0.46 304091.0 43400.0 0.9 0.9638 0.9506 865 SPBio_002792 Cc1ccc(cc1)C(=O)c2ccc(CC(=O)O)n2C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L15 compound treatment 162202.0 -95800.0 -1.94 3237.0 -257000.0 -5.36 -5.1653 -0.9056 1324 SPBio_002793 CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L16 compound treatment 280468.0 22500.0 0.46 301525.0 40800.0 0.85 0.9242 0.9574 3069698 SPBio_002794 CC(C)(C)NC[C@@H](O)COc1cccc2C(=O)CCCc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L17 compound treatment 288554.0 30600.0 0.62 278401.0 17700.0 0.37 0.6995 0.9692 1338 SPBio_002795 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L18 compound treatment 317429.0 59500.0 1.21 292667.0 32000.0 0.67 1.3236 0.9609 1215118 SPBio_002796 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4COc5ccccc5O4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L19 compound treatment 245840.0 -12100.0 -0.25 280402.0 19700.0 0.41 0.1166 0.2437 1533 SPBio_002797 Cc1cc(CC(=O)O)n(C)c1C(=O)c2ccc(Cl)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L20 compound treatment 288150.0 30200.0 0.61 257872.0 -2820.0 -0.06 0.3913 0.6364 1736 SPBio_002798 CC(C)n1c(/C=C/[C@@H](O)C[C@@H](O)CC(=O)O)c(c2ccc(F)cc2)c3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L21 compound treatment 115595.0 -142000.0 -2.89 240498.0 -20200.0 -0.42 -2.3383 -0.8017 956 SPBio_002799 CCn1nc(C(=O)O)c(=O)c2cc3OCOc3cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L22 compound treatment 267701.0 9740.0 0.2 276706.0 16000.0 0.33 0.3756 0.9686 3069699 SPBio_002800 C[C@@H]1NC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L23 mock treatment 282744.0 24800.0 0.5 330267.0 69600.0 1.45 1.3802 0.8997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 L24 mock treatment 248489.0 -9470.0 -0.19 269451.0 8760.0 0.18 -0.0067 -0.0253 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M01 mock treatment 257015.0 -946.0 -0.02 289014.0 28300.0 0.59 0.4037 0.6838 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M02 mock treatment 276263.0 18300.0 0.37 303872.0 43200.0 0.9 0.8985 0.9233 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M03 compound treatment 299149.0 41200.0 0.83 326841.0 66200.0 1.38 1.5649 0.9712 1048750 SPBio_002801 COc1ccc2[nH]c3C(=NCCc3c2c1)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M04 compound treatment 326607.0 68600.0 1.39 318964.0 58300.0 1.21 1.8425 0.9977 1005 SPBio_002802 OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M05 compound treatment 321340.0 63400.0 1.28 323615.0 62900.0 1.31 1.8355 0.9999 3069526 SPBio_002803 C[N+]1(C)CCC[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M06 compound treatment 294073.0 36100.0 0.73 300205.0 39500.0 0.82 1.0998 0.9983 1603 SPBio_002804 OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M07 compound treatment 308315.0 50400.0 1.02 340460.0 79800.0 1.66 1.8969 0.9726 2709 SPBio_002805 Cc1ncc(CO)c(CO)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M08 compound treatment 345742.0 87800.0 1.78 348003.0 87300.0 1.82 2.5446 0.9999 907320 SPBio_002806 CC(C)c1c(CN(C)C(C)Cc2ccccc2)n(C)n(c3ccccc3)c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M09 compound treatment 317684.0 59700.0 1.21 295984.0 35300.0 0.74 1.3761 0.9714 3189578 SPBio_002807 O=c1cccc2[C@@H]3CNCC(C3)Cn21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M10 compound treatment 287464.0 29500.0 0.6 274472.0 13800.0 0.29 0.626 0.9435 955 SPBio_002808 CCN(CC)CCNC(=O)c1cc(Br)c(N)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M11 compound treatment 271423.0 13500.0 0.27 306744.0 46100.0 0.96 0.8714 0.8736 1039072 SPBio_002809 CN1C2CCCC1CC(=O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M12 compound treatment 175840.0 -82100.0 -1.66 2774.0 -258000.0 -5.37 -4.9766 -0.8847 1286 SPBio_002810 Cc1cc(ccc1OCCOCC[N+](C)(C)Cc2ccccc2)C(C)(C)CC(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M13 compound treatment 349659.0 91700.0 1.86 340713.0 80000.0 1.67 2.4933 0.9985 3189579 SPBio_002811 CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M14 compound treatment 284310.0 26300.0 0.53 279991.0 19300.0 0.4 0.6621 0.9902 863 SPBio_002812 CN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M15 compound treatment 157824.0 -100000.0 -2.03 288361.0 27700.0 0.58 -1.0278 -0.487 3069527 SPBio_002813 Nc1nc(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@H](CCC(=O)O)C(=O)O)cnc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M16 compound treatment 286237.0 28300.0 0.57 286858.0 26200.0 0.55 0.7908 0.9997 1441 SPBio_002814 CN1CCC(CC1)OC(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M17 compound treatment 308272.0 50300.0 1.02 231296.0 -29400.0 -0.61 0.2882 0.2423 3189580 SPBio_002815 C[C@@H]1NCCc2cc(O)c(O)cc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M18 compound treatment 290791.0 32800.0 0.67 233713.0 -27000.0 -0.56 0.0732 0.0841 1373 SPBio_002816 CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M19 compound treatment 271194.0 13200.0 0.27 273891.0 13200.0 0.28 0.3842 0.9999 1014994 SPBio_002817 CN(C)Cc1c[nH]c2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M20 compound treatment 294503.0 36500.0 0.74 273758.0 13100.0 0.27 0.7164 0.9076 1012 SPBio_002818 Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M21 compound treatment 269657.0 11700.0 0.24 277584.0 16900.0 0.35 0.4165 0.9815 3189581 SPBio_002819 CCCCc1cc2ccccc2c(OCCN(C)C)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M22 compound treatment 278487.0 20500.0 0.42 279912.0 19200.0 0.4 0.5774 0.9998 2117332 SPBio_002820 C[C@@]12CC[C@H]3[C@@H](CC[C@]4(O)C[C@@H](O)CC[C@]34C=O)[C@@]2(O)CC[C@@H]1C5=CC(=O)OC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M23 mock treatment 274396.0 16400.0 0.33 269008.0 8320.0 0.17 0.3581 0.9536 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 M24 mock treatment 248650.0 -9310.0 -0.19 242253.0 -18400.0 -0.38 -0.4051 -0.9465 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N01 mock treatment 244745.0 -13200.0 -0.27 263217.0 2530.0 0.05 -0.1522 -0.5574 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N02 mock treatment 320801.0 62800.0 1.27 326077.0 65400.0 1.36 1.8641 0.9994 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N03 compound treatment 340020.0 82100.0 1.66 298912.0 38200.0 0.8 1.7394 0.9431 3069627 SPBio_002821 CCC(=O)OC1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N04 compound treatment 322550.0 64600.0 1.31 301531.0 40800.0 0.85 1.5275 0.9782 1764 SPBio_002822 NCC1(CC(=O)O)CCCCC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N05 compound treatment 278719.0 20800.0 0.42 329393.0 68700.0 1.43 1.3097 0.8779 1001531 SPBio_002823 COc1cc(cc(OC)c1OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](O)c4cc5OCOc5cc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N06 compound treatment 351410.0 93400.0 1.89 297745.0 37100.0 0.77 1.8855 0.9217 1694 SPBio_002824 Oc1ccc(cc1)c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N07 compound treatment 354866.0 96900.0 1.96 286830.0 26100.0 0.54 1.7742 0.8703 877 SPBio_002825 CC(C)(Oc1ccc(Cl)cc1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N08 compound treatment 351874.0 93900.0 1.9 303420.0 42700.0 0.89 1.9757 0.94 2764 SPBio_002826 CC(O)(P(=O)(O)O)P(=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N09 compound treatment 331301.0 73300.0 1.49 324752.0 64100.0 1.33 1.9951 0.9985 917 SPBio_002827 NS(=O)(=O)c1cc2c(NC(Cc3ccccc3)NS2(=O)=O)cc1C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N10 compound treatment 327027.0 69100.0 1.4 312962.0 52300.0 1.09 1.7601 0.9923 3069700 SPBio_002828 C[C@H]1NC(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N11 compound treatment 28670.0 -229000.0 -4.65 60471.0 -200000.0 -4.17 -6.2363 -0.9985 1481 SPBio_002829 Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc4ccccc14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N12 compound treatment 284455.0 26500.0 0.54 284413.0 23700.0 0.49 0.7293 0.9991 1000094 SPBio_002830 CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N13 compound treatment 295284.0 37300.0 0.76 294150.0 33500.0 0.7 1.0279 0.9992 3092 SPBio_002831 Cn1ccnc1S 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N14 compound treatment 68043.0 -190000.0 -3.85 50739.0 -210000.0 -4.37 -5.8153 -0.998 3187895 SPBio_002832 Nc1ncn(C2O[C@H](CO)[C@H](O)[C@@H]2O)c(=O)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N15 compound treatment 291727.0 33800.0 0.68 176875.0 -83800.0 -1.75 -0.7506 -0.4002 1043 SPBio_002833 O[Hg]c1c(O)c(Br)cc2c(c3ccccc3C(=O)O)c4cc(Br)c(=O)cc4oc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N16 compound treatment 276170.0 18200.0 0.37 281660.0 21000.0 0.44 0.57 0.9965 3187896 SPBio_002834 NCC1OC(O[C@@H]2C(O)[C@H](OC3C(O)C(N)CC(N)C3OC4OC(CO)C(O)C(O)C4N)O[C@@H]2CO)C(N)C(O)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N17 compound treatment 278666.0 20700.0 0.42 313378.0 52700.0 1.1 1.073 0.913 3187761 SPBio_002835 CC(CNC1CCCCC1)OC(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N18 compound treatment 260314.0 2350.0 0.05 276834.0 16100.0 0.34 0.2716 0.7994 1267 SPBio_002836 CC(=O)Nc1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N19 compound treatment 305062.0 47100.0 0.95 248301.0 -12400.0 -0.26 0.4927 0.4981 793 SPBio_002837 CCN(CC)CCOC(=O)C(C1CCCCC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N20 compound treatment 298231.0 40300.0 0.82 310512.0 49800.0 1.04 1.3112 0.9929 1604 SPBio_002838 OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N21 compound treatment 262053.0 4090.0 0.08 293782.0 33100.0 0.69 0.5462 0.7865 2080598 SPBio_002839 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@H](O)CC2CC(=O)NC(=O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N22 compound treatment 256788.0 -1170.0 -0.02 246812.0 -13900.0 -0.29 -0.2212 -0.7627 2137 SPBio_002840 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)c(O)c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N23 mock treatment 254231.0 -3730.0 -0.08 251249.0 -9440.0 -0.2 -0.1925 -0.9138 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 N24 mock treatment 238887.0 -19100.0 -0.39 251475.0 -9210.0 -0.19 -0.4092 -0.9478 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O01 mock treatment 259558.0 1600.0 0.03 275777.0 15100.0 0.31 0.2452 0.7758 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O02 mock treatment 300908.0 42900.0 0.87 266789.0 6100.0 0.13 0.7055 0.8018 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O03 compound treatment 333447.0 75500.0 1.53 282084.0 21400.0 0.45 1.3973 0.8766 3382 SPBio_002841 Cc1c(CCO)sc[n+]1Cc2cnc(C)nc2N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O04 compound treatment 274901.0 16900.0 0.34 281725.0 21000.0 0.44 0.5527 0.9927 1155 SPBio_002842 Nc1ccc(cc1)S(=O)(=O)NC(=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O05 compound treatment 273492.0 15500.0 0.31 319338.0 58600.0 1.22 1.0866 0.8612 3487152 SPBio_002843 CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O06 compound treatment 293489.0 35500.0 0.72 301325.0 40600.0 0.85 1.1079 0.9968 1513 SPBio_002844 CCOC(=O)c1ccc(N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O07 compound treatment 348573.0 90600.0 1.84 345528.0 84800.0 1.77 2.5487 0.9998 2041 SPBio_002845 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O08 compound treatment 277653.0 19700.0 0.4 280251.0 19600.0 0.41 0.5705 0.9999 1242 SPBio_002846 CN(CS(=O)(=O)O)c1c(C)n(C)n(c2ccccc2)c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O09 compound treatment 244669.0 -13300.0 -0.27 251759.0 -8930.0 -0.19 -0.3221 -0.9836 1015808 SPBio_002847 Cc1cc2nc3c(=O)[nH]c(=O)nc3n(CC(O)C(O)C(O)CO)c2cc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O10 compound treatment 291352.0 33400.0 0.68 285091.0 24400.0 0.51 0.8381 0.99 1064 SPBio_002848 [O-][N+](=O)O[C@@H]1CO[C@@H]2[C@H](CO[C@H]12)O[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O11 compound treatment 11056.0 -247000.0 -5.01 50979.0 -210000.0 -4.37 -6.6287 -0.9977 3189582 SPBio_002849 CC[C@H]1CN2CCC1C[C@H]2[C@H](O)c3ccnc4ccc(OC)cc34 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O12 compound treatment 38359.0 -220000.0 -4.45 34045.0 -227000.0 -4.72 -6.4867 -0.9996 1668673 SPBio_002850 Nc1ccc(cc1)S(=O)(=O)Nc2ccc(Cl)nn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O13 compound treatment 245735.0 -12200.0 -0.25 308440.0 47800.0 0.99 0.5282 0.5152 824 SPBio_002851 CC[C@]1(CCCN2CCc3c4[C@@H]21)C[C@@](O)(C(=O)OC)n4c5ccccc35 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O14 compound treatment 283930.0 26000.0 0.53 274107.0 13400.0 0.28 0.5699 0.9561 1467 SPBio_002852 CCCCOc1ccc(OCCCN2CCOCC2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O15 compound treatment 293175.0 35200.0 0.71 247716.0 -13000.0 -0.27 0.3137 0.4109 3069528 SPBio_002853 C/C=C\1/C[C@@H](C)[C@](O)(CO)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O16 compound treatment 256171.0 -1790.0 -0.04 262539.0 1850.0 0.04 0.0016 0.0301 3069574 SPBio_002854 CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O17 compound treatment 296245.0 38300.0 0.78 280119.0 19400.0 0.4 0.835 0.9539 3187609 SPBio_002855 C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23CN1C)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O18 compound treatment 306616.0 48700.0 0.99 265905.0 5220.0 0.11 0.7743 0.7803 2081008 SPBio_002856 C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)C)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O19 compound treatment 242886.0 -15100.0 -0.31 275861.0 15200.0 0.32 0.0074 0.0168 3187610 SPBio_002857 CC[C@@H](C)C(=O)O[C@H]1[C@H](O)[C@H]2[C@@H](CN3C[C@@H](C)CC[C@H]3[C@@]2(C)O)C4C[C@]5(O[C@]6(O)[C@H]7[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@H]5[C@@]41O)[C@@]7(C)CC[C@@H]6OC(=O)C(C)(O)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O20 compound treatment 3189.0 -255000.0 -5.16 2596.0 -258000.0 -5.38 -7.4542 -0.9998 759 SPBio_002858 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O21 compound treatment 274359.0 16400.0 0.33 283592.0 22900.0 0.48 0.5725 0.9844 3069529 SPBio_002859 C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@]6(C[C@@H](O[C@@H]7OC(CO)[C@@H](O)[C@@H](O)C7O)[C@@H](O)C(CO)O6)O[C@H]8OC(C)[C@H](O)[C@H](O)C8O)N9C[C@@H](C)CC[C@H]19 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O22 compound treatment 45349.0 -213000.0 -4.31 21862.0 -239000.0 -4.98 -6.566 -0.9974 3187749 SPBio_002860 CO/N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC(=O)N)\c3ccco3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O23 mock treatment 268714.0 10800.0 0.22 249747.0 -10900.0 -0.23 -0.007 -0.0223 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 O24 mock treatment 262193.0 4230.0 0.09 276486.0 15800.0 0.33 0.2934 0.8626 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P01 mock treatment 251621.0 -6340.0 -0.13 270707.0 10000.0 0.21 0.0567 0.2313 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P02 mock treatment 280649.0 22700.0 0.46 259040.0 -1650.0 -0.03 0.3009 0.6525 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P03 compound treatment 336751.0 78800.0 1.6 291521.0 30800.0 0.64 1.5837 0.9199 890 SPBio_002861 COc1ccc2cc(ccc2c1)[C@H](C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P04 compound treatment 245581.0 -12400.0 -0.25 266234.0 5540.0 0.12 -0.0958 -0.3467 3069701 SPBio_002862 C[C@H](O)C(=O)Nc1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P05 compound treatment 202124.0 -55800.0 -1.13 221122.0 -39600.0 -0.82 -1.3833 -0.9879 244 SPBio_002863 CC[N+](C)(CC)CCC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P06 compound treatment 276438.0 18500.0 0.37 251691.0 -9000.0 -0.19 0.1323 0.3159 3487261 SPBio_002864 COCC(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)N(C)CC(O)CO)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P07 compound treatment 255092.0 -2870.0 -0.06 268114.0 7420.0 0.15 0.0683 0.413 1431 SPBio_002865 Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P08 compound treatment 284300.0 26300.0 0.53 271884.0 11200.0 0.23 0.5425 0.931 856 SPBio_002866 Cn1c(=O)n(C)c2nc[nH]c2c1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P09 compound treatment 278773.0 20800.0 0.42 243398.0 -17300.0 -0.36 0.0436 0.0786 3187762 SPBio_002867 CC1CC(CC(C)(C)N1C)OC(=O)C(O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P10 compound treatment 254464.0 -3500.0 -0.07 274083.0 13400.0 0.28 0.1472 0.5112 1222 SPBio_002868 Cn1cnc2n(C)c(=O)[nH]c(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P11 compound treatment 144306.0 -114000.0 -2.3 173042.0 -87600.0 -1.83 -2.9204 -0.9934 3383 SPBio_002869 Cc1cc(no1)C(=O)NNCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P12 compound treatment 241612.0 -16300.0 -0.33 236275.0 -24400.0 -0.51 -0.594 -0.9785 687 SPBio_002870 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P13 compound treatment 65578.0 -192000.0 -3.9 247581.0 -13100.0 -0.27 -2.9509 -0.7548 2105063 SPBio_002871 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P14 compound treatment 225781.0 -32200.0 -0.65 240390.0 -20300.0 -0.42 -0.7603 -0.978 989 SPBio_002872 NC(=N)NCCCCNC(=N)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P15 compound treatment 216905.0 -41100.0 -0.83 230410.0 -30300.0 -0.63 -1.0346 -0.9906 2752 SPBio_002873 COc1ccc2Sc3ccccc3N(C[C@H](C)CN(C)C)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P16 compound treatment 245525.0 -12400.0 -0.25 242136.0 -18600.0 -0.39 -0.4516 -0.9786 3060919 SPBio_002874 CN1C2CC(CC1C3OC32)OC(=O)[C@H](CO)c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P17 compound treatment 210037.0 -47900.0 -0.97 241320.0 -19400.0 -0.4 -0.9723 -0.9242 1370 SPBio_002875 C/C=C(/C(=C/C)/c1ccc(O)cc1)\c2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P18 compound treatment 245844.0 -12100.0 -0.25 232288.0 -28400.0 -0.59 -0.5921 -0.9242 3487262 SPBio_002876 OCCN(C(=O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P19 compound treatment 275105.0 17100.0 0.35 246254.0 -14400.0 -0.3 0.0331 0.0721 1328 SPBio_002877 OC(CCN1CCCCC1)(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P20 compound treatment 235497.0 -22500.0 -0.46 247164.0 -13500.0 -0.28 -0.5213 -0.9734 446 SPBio_002878 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P21 compound treatment 255643.0 -2320.0 -0.05 249556.0 -11100.0 -0.23 -0.1972 -0.8334 794 SPBio_002879 Nc1cc(c[nH]c1=O)c2ccncc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P22 compound treatment 236286.0 -21700.0 -0.44 253656.0 -7030.0 -0.15 -0.4143 -0.8945 1327 SPBio_002880 C[N+](C)(C)CCOC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P23 mock treatment 238600.0 -19400.0 -0.39 232546.0 -28100.0 -0.59 -0.6921 -0.981 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2166 P24 mock treatment 248810.0 -9150.0 -0.19 216619.0 -44100.0 -0.92 -0.7804 -0.8331 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A01 mock treatment 239949.0 -28000.0 -0.57 206458.0 -66600.0 -1.39 -1.3835 -0.9222 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A02 mock treatment 259516.0 -8460.0 -0.17 262802.0 -10300.0 -0.21 -0.273 -0.9938 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A03 compound treatment 177961.0 -90000.0 -1.82 173096.0 -100000.0 -2.08 -2.7636 -0.9978 1300 SPBio_002881 OC(=O)c1cccnc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A04 compound treatment 233479.0 -34500.0 -0.7 203117.0 -70000.0 -1.46 -1.5255 -0.9434 1073908 SPBio_002882 CC[N+](CC)(CC(=O)Nc1c(C)cccc1C)Cc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A05 compound treatment 232825.0 -35100.0 -0.71 243395.0 -29700.0 -0.62 -0.9415 -0.9975 2819 SPBio_002883 CCC1(C)CC(=O)NC(=O)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A06 compound treatment 244259.0 -23700.0 -0.48 242525.0 -30600.0 -0.64 -0.7904 -0.9904 1322 SPBio_002884 COc1cc2ccc(=O)oc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A07 compound treatment 236156.0 -31800.0 -0.65 246771.0 -26300.0 -0.55 -0.844 -0.9968 3187897 SPBio_002885 C[C@]12[C@H](CC[C@]2(O)[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3C[C@H]1O)C5=CC(=O)OC5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A08 compound treatment 206235.0 -61700.0 -1.25 248433.0 -24700.0 -0.51 -1.2485 -0.9227 1081653 SPBio_002886 Clc1ccc(C(Cn2ccnc2)OCC=C)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A09 compound treatment 246208.0 -21800.0 -0.44 261241.0 -11900.0 -0.25 -0.4868 -0.9625 4370 SPBio_002887 CNCC(O)C(O)C(O)C(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A10 compound treatment 2606.0 -265000.0 -5.38 2681.0 -270000.0 -5.63 -7.7877 -0.9997 1203 SPBio_002888 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@@H]3C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A11 compound treatment 248277.0 -19700.0 -0.4 244244.0 -28900.0 -0.6 -0.7075 -0.9802 3172726 SPBio_002889 C[C@]12C3CCC(O3)[C@]2(C)C(=O)OC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A12 compound treatment 234212.0 -33800.0 -0.68 222183.0 -50900.0 -1.06 -1.2341 -0.9775 2060138 SPBio_002890 C[C@]1([C@H]2[C@H](C(=O)O)[C@]3(CC(=C)[C@@]4(O)C3)[C@@H](CC4)[C@]52OC1=O)[C@@H](O)C=C5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A13 compound treatment 129968.0 -138000.0 -2.8 25068.0 -248000.0 -5.17 -5.6322 -0.9585 1999 SPBio_002891 Oc1c(I)cc(Cl)c2cccnc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A14 compound treatment 238383.0 -29600.0 -0.6 253162.0 -19900.0 -0.42 -0.718 -0.9839 3480627 SPBio_002892 CC(C)NCC(O)c1ccc(NS(=O)(=O)C)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A15 compound treatment 222702.0 -45300.0 -0.92 248364.0 -24700.0 -0.52 -1.0134 -0.9628 838 SPBio_002893 COc1ccc(C(=O)c2ccccc2)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A16 compound treatment 271714.0 3740.0 0.08 286676.0 13600.0 0.28 0.2535 0.8662 3188025 SPBio_002894 CN1C2CC(O)C1CC(=O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A17 compound treatment 222540.0 -45400.0 -0.92 246045.0 -27100.0 -0.56 -1.0499 -0.9722 681 SPBio_002895 CC(CN1c2ccccc2Sc3ccccc13)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A18 compound treatment 232117.0 -35900.0 -0.73 229147.0 -44000.0 -0.92 -1.1615 -0.9935 3855 SPBio_002896 C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A19 compound treatment 221010.0 -47000.0 -0.95 238892.0 -34200.0 -0.71 -1.1772 -0.9898 1225 SPBio_002897 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A20 compound treatment 223446.0 -44500.0 -0.9 249259.0 -23800.0 -0.5 -0.9896 -0.9604 1040327 SPBio_002898 CC(=O)Nc1cc2ccccc2oc1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A21 compound treatment 231935.0 -36000.0 -0.73 214233.0 -58900.0 -1.23 -1.3839 -0.9694 3487233 SPBio_002899 CC(O)Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A22 compound treatment 243848.0 -24100.0 -0.49 223698.0 -49400.0 -1.03 -1.0737 -0.9421 1120 SPBio_002900 Oc1ccc(cc1[N+](=O)[O-])[As](=O)(O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A23 mock treatment 217661.0 -50300.0 -1.02 199983.0 -73100.0 -1.52 -1.7984 -0.981 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 A24 mock treatment 236641.0 -31300.0 -0.64 236348.0 -36800.0 -0.77 -0.9906 -0.9957 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B01 mock treatment 218246.0 -49700.0 -1.01 238184.0 -34900.0 -0.73 -1.2273 -0.9872 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B02 mock treatment 260796.0 -7180.0 -0.15 265007.0 -8100.0 -0.17 -0.2222 -0.9973 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B03 compound treatment 286580.0 18600.0 0.38 255743.0 -17400.0 -0.36 0.011 0.021 3069812 SPBio_002901 CCOC(=O)c1cncn1C(C)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B04 mock treatment 276095.0 8120.0 0.16 262525.0 -10600.0 -0.22 -0.0394 -0.1433 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B05 compound treatment 285804.0 17800.0 0.36 327050.0 53900.0 1.12 1.0503 0.8897 3188157 SPBio_002902 CC[N+](CC)(CC)CCC(O)(C1CCCCC1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B06 mock treatment 289936.0 22000.0 0.45 290093.0 17000.0 0.35 0.5651 0.9935 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B07 compound treatment 239980.0 -28000.0 -0.57 273144.0 38.8 0.0 -0.4007 -0.7061 3487585 SPBio_002903 CC(C)(C)NCC(O)COc1ccccc1C2CCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B08 mock treatment 247759.0 -20200.0 -0.41 258598.0 -14500.0 -0.3 -0.5035 -0.9888 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B09 compound treatment 243590.0 -24400.0 -0.49 276855.0 3750.0 0.08 -0.2943 -0.5881 3188158 SPBio_002904 CCOC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C)C(=O)COC(=O)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B10 mock treatment 255971.0 -12000.0 -0.24 248197.0 -24900.0 -0.52 -0.539 -0.9404 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B11 compound treatment 54965.0 -213000.0 -4.32 63599.0 -210000.0 -4.36 -6.1397 -1.0 3069813 SPBio_002905 Clc1ccc(C(Cn2ccnc2)OCc3csc4c(Cl)cccc34)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B12 mock treatment 277640.0 9670.0 0.2 282304.0 9200.0 0.19 0.2741 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B13 compound treatment 288068.0 20100.0 0.41 284363.0 11300.0 0.23 0.4539 0.9656 3188159 SPBio_002906 CCOc1cc(CC(=O)N[C@@H](CC(C)C)c2ccccc2N3CCCCC3)ccc1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B14 mock treatment 257910.0 -10100.0 -0.2 252619.0 -20500.0 -0.43 -0.446 -0.9429 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B15 compound treatment 226882.0 -41100.0 -0.83 247536.0 -25600.0 -0.53 -0.9657 -0.9767 3168 SPBio_002907 NS(=O)(=O)c1cc(cc(N2CCCC2)c1Oc3ccccc3)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B16 mock treatment 276580.0 8610.0 0.17 257373.0 -15700.0 -0.33 -0.1084 -0.2919 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B17 compound treatment 239559.0 -28400.0 -0.58 259681.0 -13400.0 -0.28 -0.6051 -0.9449 3188160 SPBio_002908 CC(=O)c1ccc2Sc3ccccc3N(CCCN4CCC(CCO)CC4)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B18 mock treatment 269018.0 1050.0 0.02 253806.0 -19300.0 -0.4 -0.2693 -0.6689 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B19 compound treatment 132309.0 -136000.0 -2.75 155291.0 -118000.0 -2.45 -3.6803 -0.9984 943 SPBio_002909 CCCCC1C(=O)N(N(C1=O)c2ccc(O)cc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B20 mock treatment 236877.0 -31100.0 -0.63 239721.0 -33400.0 -0.7 -0.9375 -0.9988 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B21 compound treatment 251342.0 -16600.0 -0.34 252929.0 -20200.0 -0.42 -0.5356 -0.994 3069814 SPBio_002910 CCC1NC(=O)c2cc(c(Cl)cc2N1)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B22 mock treatment 264964.0 -3010.0 -0.06 233731.0 -39400.0 -0.82 -0.6232 -0.7576 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B23 mock treatment 235827.0 -32100.0 -0.65 248322.0 -24800.0 -0.52 -0.8259 -0.9933 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 B24 mock treatment 233609.0 -34400.0 -0.7 238937.0 -34200.0 -0.71 -0.9959 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C01 mock treatment 245897.0 -22100.0 -0.45 238487.0 -34600.0 -0.72 -0.8264 -0.9737 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C02 mock treatment 242175.0 -25800.0 -0.52 251314.0 -21800.0 -0.45 -0.6908 -0.9975 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C03 compound treatment 198475.0 -69500.0 -1.41 161452.0 -112000.0 -2.33 -2.641 -0.9711 1022907 SPBio_002911 CC(=O)c1cc2ccccc2oc1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C04 compound treatment 220186.0 -47800.0 -0.97 201278.0 -71800.0 -1.5 -1.7431 -0.9779 3188026 SPBio_002912 CCN1CCC[C@H]1CNC(=O)c2c(OC)ccc(Br)c2OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C05 compound treatment 270205.0 2230.0 0.05 229135.0 -44000.0 -0.92 -0.6157 -0.6714 3187898 SPBio_002913 OCC1O[C@@H](Oc2cc3ccc(=O)oc3cc2O)C(O)[C@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C06 compound treatment 315697.0 47700.0 0.97 274646.0 1540.0 0.03 0.7068 0.7302 864 SPBio_002914 Oc1noc2CNCCc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C07 compound treatment 277682.0 9710.0 0.2 283563.0 10500.0 0.22 0.2932 0.9987 2776 SPBio_002915 OC(=O)Cc1ccc(cc1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C08 compound treatment 274706.0 6730.0 0.14 269476.0 -3630.0 -0.08 0.0431 0.2759 1134931 SPBio_002916 Cc1ccc2n3CCNC4CCCc(c43)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C09 compound treatment 265425.0 -2550.0 -0.05 248766.0 -24300.0 -0.51 -0.3951 -0.7751 1012530 SPBio_002917 CCCCOC(=O)c1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C10 compound treatment 264414.0 -3560.0 -0.07 255061.0 -18000.0 -0.38 -0.3168 -0.8277 1512 SPBio_002918 CC(C)NCC(O)c1ccc2ccccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C11 compound treatment 250924.0 -17000.0 -0.35 287030.0 13900.0 0.29 -0.0393 -0.087 1299 SPBio_002919 Nc1ccc(cc1)C(=O)NCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C12 compound treatment 233800.0 -34200.0 -0.69 273903.0 798.0 0.02 -0.4781 -0.6899 3480607 SPBio_002920 COc1ccccc1N2CCN(CC(O)COc3cccc4ccccc34)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C13 compound treatment 257307.0 -10700.0 -0.22 273634.0 529.0 0.01 -0.1451 -0.6702 1231 SPBio_002921 CC(C)C[C@H](NC(=O)C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C14 compound treatment 259941.0 -8030.0 -0.16 266337.0 -6770.0 -0.14 -0.2148 -0.9974 907524 SPBio_002922 CCCCNc1c(C(=O)OCC)c(C)nc2n(CC)ncc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C15 compound treatment 236174.0 -31800.0 -0.64 246851.0 -26300.0 -0.55 -0.8426 -0.9967 1258 SPBio_002923 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCNCC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C16 compound treatment 250991.0 -17000.0 -0.34 241906.0 -31200.0 -0.65 -0.703 -0.9558 2372 SPBio_002924 COc1cc(ccc1OC(F)F)c2ccc(=O)[nH]n2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C17 compound treatment 214290.0 -53700.0 -1.09 241620.0 -31500.0 -0.66 -1.2334 -0.9706 3059213 SPBio_002925 COc1ccc(C(=O)c2ccccc2O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C18 compound treatment 258149.0 -9820.0 -0.2 243944.0 -29200.0 -0.61 -0.5704 -0.8922 733 SPBio_002926 CC1(CC2CC3(C)C1)CC(N)(C2)C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C19 compound treatment 235710.0 -32300.0 -0.65 249677.0 -23400.0 -0.49 -0.8076 -0.9896 3187899 SPBio_002927 C[C@@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C20 compound treatment 242269.0 -25700.0 -0.52 255667.0 -17400.0 -0.36 -0.6253 -0.9845 2742 SPBio_002928 OC(=O)/C=C/c1ccc(Cn2ccnc2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C21 compound treatment 248199.0 -19800.0 -0.4 258363.0 -14700.0 -0.31 -0.5006 -0.9913 1019709 SPBio_002929 C[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C22 compound treatment 249299.0 -18700.0 -0.38 237551.0 -35600.0 -0.74 -0.7914 -0.9514 2245 SPBio_002930 C(N1CCN(CC1)c2ncccn2)c3ccc4OCOc4c3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C23 mock treatment 222417.0 -45600.0 -0.92 229007.0 -44100.0 -0.92 -1.3027 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 C24 mock treatment 238402.0 -29600.0 -0.6 215186.0 -57900.0 -1.21 -1.2771 -0.9479 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D01 mock treatment 248767.0 -19200.0 -0.39 214742.0 -58400.0 -1.22 -1.1351 -0.8891 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D02 mock treatment 270520.0 2550.0 0.05 269190.0 -3920.0 -0.08 -0.0212 -0.2192 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D03 compound treatment 286881.0 18900.0 0.38 279262.0 6160.0 0.13 0.3617 0.8949 1267101 SPBio_002931 CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN4CCOCC4)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D04 mock treatment 265183.0 -2790.0 -0.06 310329.0 37200.0 0.78 0.5084 0.6538 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D05 compound treatment 285972.0 18000.0 0.36 289603.0 16500.0 0.34 0.5011 0.9996 1487 SPBio_002932 CCC(Cc1c(I)cc(I)c(N)c1I)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D06 mock treatment 283724.0 15800.0 0.32 278214.0 5110.0 0.11 0.3011 0.8944 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D07 compound treatment 290120.0 22100.0 0.45 317156.0 44100.0 0.92 0.9664 0.9459 3188161 SPBio_002933 CC(C)(C)C(=O)OCOC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](/N=C/N3CCCCCC3)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D08 mock treatment 272650.0 4680.0 0.09 266239.0 -6870.0 -0.14 -0.0341 -0.1987 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D09 compound treatment 279655.0 11700.0 0.24 272808.0 -297.0 -0.01 0.1631 0.6884 3188162 SPBio_002934 CCC(=O)OC(Cc1ccccc1)(C(C)CN(C)C)c2ccccc2.OS(=O)(=O)c1ccc2ccccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D10 mock treatment 291144.0 23200.0 0.47 294065.0 21000.0 0.44 0.6409 0.9993 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D11 compound treatment 251456.0 -16500.0 -0.33 294465.0 21400.0 0.44 0.0779 0.1399 772 SPBio_002935 CCN1CCCC(C1)OC(=O)C(c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D12 mock treatment 261150.0 -6820.0 -0.14 282004.0 8900.0 0.19 0.0333 0.1439 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D13 compound treatment 2665.0 -265000.0 -5.38 2495.0 -271000.0 -5.64 -7.7896 -0.9997 3069815 SPBio_002936 OC[C@H]1O[C@H](C[C@H]1O)n2cc(c(=O)[nH]c2=O)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D14 mock treatment 269965.0 1990.0 0.04 273678.0 573.0 0.01 0.037 0.8785 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D15 compound treatment 253116.0 -14900.0 -0.3 259546.0 -13600.0 -0.28 -0.4127 -0.9995 1001977 SPBio_002937 CC(C)NCC(O)COc1ccccc1OCC=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D16 mock treatment 253840.0 -14100.0 -0.29 254296.0 -18800.0 -0.39 -0.4797 -0.9882 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D17 compound treatment 239802.0 -28200.0 -0.57 268495.0 -4610.0 -0.1 -0.4717 -0.8146 1434439 SPBio_002938 Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D18 mock treatment 240781.0 -27200.0 -0.55 254901.0 -18200.0 -0.38 -0.658 -0.9833 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D19 compound treatment 275958.0 7990.0 0.16 255511.0 -17600.0 -0.37 -0.1447 -0.3612 3069816 SPBio_002939 CCCOc1cc(N)ccc1C(=O)OCCN(CC)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D20 mock treatment 253882.0 -14100.0 -0.29 235785.0 -37300.0 -0.78 -0.7518 -0.9076 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D21 compound treatment 252508.0 -15500.0 -0.31 279309.0 6200.0 0.13 -0.1303 -0.3842 1672 SPBio_002940 OC(=O)CCc1nc(c(o1)c2ccccc2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D22 mock treatment 250770.0 -17200.0 -0.35 257064.0 -16000.0 -0.33 -0.4829 -0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D23 mock treatment 219547.0 -48400.0 -0.98 241249.0 -31900.0 -0.66 -1.1635 -0.9818 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 D24 mock treatment 217269.0 -50700.0 -1.03 231116.0 -42000.0 -0.87 -1.3454 -0.9968 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E01 mock treatment 262070.0 -5900.0 -0.12 277804.0 4700.0 0.1 -0.0154 -0.0996 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E02 mock treatment 250167.0 -17800.0 -0.36 271410.0 -1700.0 -0.04 -0.2802 -0.7726 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E03 compound treatment 322728.0 54800.0 1.11 319134.0 46000.0 0.96 1.463 0.9973 2732 SPBio_002941 Cc1cc(=O)oc2cc(O)ccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E04 compound treatment 284451.0 16500.0 0.33 277508.0 4400.0 0.09 0.3011 0.8691 3188027 SPBio_002942 CCN(CC)CCOC(=O)C1(CCCC1)c2ccc(cc2)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E05 compound treatment 227578.0 -40400.0 -0.82 260220.0 -12900.0 -0.27 -0.7689 -0.8922 1978 SPBio_002943 OC(=O)/C=C/c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E06 compound treatment 282295.0 14300.0 0.29 302349.0 29200.0 0.61 0.6361 0.9425 2098610 SPBio_002944 C1CC1C(NC2=NCCO2)C3CC3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E07 compound treatment 289390.0 21400.0 0.43 286201.0 13100.0 0.27 0.4999 0.9749 3069737 SPBio_002945 CN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E08 compound treatment 289860.0 21900.0 0.44 266806.0 -6300.0 -0.13 0.221 0.4775 3723 SPBio_002946 CN(C)CCCSC(=N)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E09 compound treatment 293727.0 25800.0 0.52 272597.0 -508.0 -0.01 0.3617 0.6926 2743 SPBio_002947 CC(C)(C(=O)c1cccnc1)c2cccnc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E10 compound treatment 259003.0 -8970.0 -0.18 282479.0 9370.0 0.2 0.0095 0.0356 3069774 SPBio_002948 CO[C@H]1[C@H](O)C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E11 compound treatment 279904.0 11900.0 0.24 268192.0 -4910.0 -0.1 0.0987 0.3756 3202 SPBio_002949 COc1ccccc1N2CCN(CCCNc3cc(=O)n(C)c(=O)n3C)CC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E12 compound treatment 263560.0 -4410.0 -0.09 235206.0 -37900.0 -0.79 -0.6216 -0.7822 3069775 SPBio_002950 CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E13 compound treatment 263922.0 -4050.0 -0.08 175763.0 -97300.0 -2.03 -1.492 -0.7351 23081 SPBio_002951 Fc1ccc(cc1)C(CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4)c5ccc(F)cc5 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E14 compound treatment 298603.0 30600.0 0.62 268222.0 -4880.0 -0.1 0.3672 0.5835 3188028 SPBio_002952 CC1O[C@@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4CCC3=C2)c6ccc(=O)oc6)C(O)[C@@H](O)[C@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E15 compound treatment 269513.0 1540.0 0.03 284723.0 11600.0 0.24 0.1932 0.7918 1472 SPBio_002953 CC(C)Cc1ccc(cc1)[C@H](C)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E16 compound treatment 4865.0 -263000.0 -5.33 4450.0 -269000.0 -5.6 -7.7293 -0.9997 2549 SPBio_002954 C[n+]1cc2c3OCOc3ccc2c4ccc5cc6OCOc6cc5c14 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E17 compound treatment 308874.0 40900.0 0.83 308158.0 35100.0 0.73 1.1027 0.998 3187900 SPBio_002955 CC(=O)O[C@H]1CC[C@@H]2[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]4(OC(=O)C)C#C)[C@@H]3CCC2=C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E18 compound treatment 308966.0 41000.0 0.83 298604.0 25500.0 0.53 0.9633 0.9766 3069776 SPBio_002956 C[C@]1(C[C@H](O)[C@@]2(O)C=CO[C@H](OC3OC(CO)C(O)C(O)C3O)C12)OC(=O)/C=C\c4ccccc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E19 compound treatment 295220.0 27200.0 0.55 260118.0 -13000.0 -0.27 0.1993 0.324 1440 SPBio_002957 COc1ccc2cc(CCC(=O)C)ccc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E20 compound treatment 278757.0 10800.0 0.22 297648.0 24500.0 0.51 0.5161 0.9282 3188029 SPBio_002958 C[C@@H]1CCC2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@]43C)[C@@H]2[C@H]1C)C(=O)O[C@@H]6OC(CO[C@@H]7OC(CO)[C@@H](O[C@@H]8OC(C)[C@H](O)[C@H](O)C8O)[C@@H](O)C7O)[C@@H](O)[C@@H](O)C6O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E21 compound treatment 263828.0 -4140.0 -0.08 303299.0 30200.0 0.63 0.3854 0.6073 907434 SPBio_002959 CNCCC(Oc1ccccc1OC)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E22 compound treatment 277128.0 9160.0 0.19 295112.0 22000.0 0.46 0.4554 0.9208 3069777 SPBio_002960 CC(=C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CCC(O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E23 mock treatment 262522.0 -5450.0 -0.11 258938.0 -14200.0 -0.3 -0.2868 -0.9101 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 E24 mock treatment 254259.0 -13700.0 -0.28 249708.0 -23400.0 -0.49 -0.5413 -0.9646 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F01 mock treatment 266242.0 -1730.0 -0.04 276360.0 3250.0 0.07 0.0231 0.303 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F02 mock treatment 277408.0 9440.0 0.19 283583.0 10500.0 0.22 0.2896 0.9978 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F03 compound treatment 273629.0 5660.0 0.11 299755.0 26600.0 0.56 0.4737 0.8355 3188163 SPBio_002961 CN1C(=O)CC(C1=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F04 mock treatment 336377.0 68400.0 1.39 309164.0 36100.0 0.75 1.5118 0.9585 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F05 compound treatment 286290.0 18300.0 0.37 292084.0 19000.0 0.4 0.5422 0.9995 2957 SPBio_002962 CNC(=O)c1c(I)c(N(C)C(=O)C)c(I)c(C(=O)NCC(=O)Nc2c(I)c(C(=O)O)c(I)c(C(=O)NCCO)c2I)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F06 mock treatment 317733.0 49800.0 1.01 316375.0 43300.0 0.9 1.3507 0.9984 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F07 compound treatment 280035.0 12100.0 0.24 314017.0 40900.0 0.85 0.7756 0.8747 3069817 SPBio_002963 CN(C/C=C/c1ccccc1)Cc2cccc3ccccc23 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F08 mock treatment 311122.0 43100.0 0.87 278615.0 5510.0 0.11 0.6997 0.7931 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F09 compound treatment 264409.0 -3560.0 -0.07 302962.0 29900.0 0.62 0.3887 0.6208 907413 SPBio_002964 CCCNC(C)(C)COC(=O)c1ccccc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F10 mock treatment 335325.0 67400.0 1.37 313467.0 40400.0 0.84 1.5601 0.9729 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F11 compound treatment 323712.0 55700.0 1.13 297240.0 24100.0 0.5 1.1546 0.9335 1666 SPBio_002965 Cc1[nH]c(=O)c(C#N)cc1c2ccncc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F12 mock treatment 269083.0 1110.0 0.02 305264.0 32200.0 0.67 0.4897 0.7305 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F13 compound treatment 272341.0 4370.0 0.09 298491.0 25400.0 0.53 0.4366 0.8142 4382 SPBio_002966 CC[N+](C)(CC)CCOC(=O)C1c2ccccc2Oc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F14 mock treatment 302222.0 34200.0 0.69 307275.0 34200.0 0.71 0.9943 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F15 compound treatment 2086.0 -266000.0 -5.39 3000.0 -270000.0 -5.63 -7.7905 -0.9998 2586 SPBio_002967 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](C(=O)O)c3ccsc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F16 mock treatment 296230.0 28300.0 0.57 285838.0 12700.0 0.27 0.5926 0.9388 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F17 compound treatment 261006.0 -6970.0 -0.14 265305.0 -7800.0 -0.16 -0.2148 -0.9976 3188276 SPBio_002968 CCSc1ccc2Sc3ccccc3N(CCCN4CCN(C)CC4)c2c1.OC(CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F18 mock treatment 243447.0 -24500.0 -0.5 294406.0 21300.0 0.44 -0.0378 -0.0567 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F19 compound treatment 281463.0 13500.0 0.27 296589.0 23500.0 0.49 0.5393 0.9622 1778 SPBio_002969 Nc1ccc(O)c(c1)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F20 mock treatment 277630.0 9660.0 0.2 281960.0 8850.0 0.18 0.2689 0.9996 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F21 compound treatment 261984.0 -5990.0 -0.12 283228.0 10100.0 0.21 0.0633 0.26 3047 SPBio_002970 C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)C(=C3[C@H]2OC1=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F22 mock treatment 239748.0 -28200.0 -0.57 253832.0 -19300.0 -0.4 -0.6885 -0.985 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F23 mock treatment 280242.0 12300.0 0.25 290063.0 17000.0 0.35 0.4257 0.9853 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 F24 mock treatment 225802.0 -42200.0 -0.85 262753.0 -10400.0 -0.22 -0.757 -0.8586 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G01 mock treatment 256846.0 -11100.0 -0.23 268184.0 -4920.0 -0.1 -0.232 -0.9363 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G02 mock treatment 293136.0 25200.0 0.51 270418.0 -2690.0 -0.06 0.3211 0.6258 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G03 compound treatment 264828.0 -3140.0 -0.06 287954.0 14800.0 0.31 0.1737 0.5498 3069738 SPBio_002971 CC(C)NCC(O)c1ccc(O)c(O)c1.OC(C(O)C(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G04 compound treatment 407963.0 140000.0 2.84 290325.0 17200.0 0.36 2.2604 0.7902 1327636 SPBio_002972 COc1ccc2c(c1)C(=O)N(CCc3ccc(cc3)S(=O)(=O)NC(=O)NC4CCCCC4)C(=O)C2(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G05 compound treatment 254165.0 -13800.0 -0.28 249229.0 -23900.0 -0.5 -0.5497 -0.963 1001471 SPBio_002973 Oc1ccc(OCc2ccccc2)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G06 compound treatment 297511.0 29500.0 0.6 282935.0 9830.0 0.2 0.5682 0.8979 3069778 SPBio_002974 CN1CCC(=C2c3ccsc3CCc4ccccc24)CC1.OC(CC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G07 compound treatment 291284.0 23300.0 0.47 298400.0 25300.0 0.53 0.7068 0.9985 1025776 SPBio_002975 Nc1ccccc1S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G08 compound treatment 314030.0 46100.0 0.93 315672.0 42600.0 0.89 1.2873 0.9997 3188030 SPBio_002976 NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@H](O)C2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G09 compound treatment 262505.0 -5470.0 -0.11 284683.0 11600.0 0.24 0.0922 0.3472 3060043 SPBio_002977 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CCC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G10 compound treatment 259191.0 -8780.0 -0.18 308922.0 35800.0 0.75 0.4017 0.5237 1057366 SPBio_002978 NS(=O)(=O)c1cc2c(NC(CC3CCCC3)NS2(=O)=O)cc1Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G11 compound treatment 273581.0 5610.0 0.11 300031.0 26900.0 0.56 0.477 0.8335 907370 SPBio_002979 CCCCCN(CCCCC)C(=O)C(CCC(=O)O)NC(=O)c1ccc(Cl)c(Cl)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G12 compound treatment 310553.0 42600.0 0.86 284502.0 11400.0 0.24 0.7783 0.8693 3177109 SPBio_002980 COCCCC/C(=N\OCCN)/c1ccc(cc1)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G13 compound treatment 250792.0 -17200.0 -0.35 271887.0 -1220.0 -0.03 -0.2642 -0.7566 117 SPBio_002981 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G14 compound treatment 2476.0 -265000.0 -5.38 2281.0 -271000.0 -5.64 -7.7955 -0.9997 3069779 SPBio_002982 NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)Cc4cccs4)C3=O)C(=O)O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G15 compound treatment 249252.0 -18700.0 -0.38 262322.0 -10800.0 -0.22 -0.4272 -0.9687 1000135 SPBio_002983 CC(C(=O)O)c1ccc(c(F)c1)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G16 compound treatment 267459.0 -514.0 -0.01 264844.0 -8260.0 -0.17 -0.1291 -0.7485 1000221 SPBio_002984 CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)SCF 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G17 compound treatment 255342.0 -12600.0 -0.26 280051.0 6950.0 0.14 -0.0787 -0.2677 115 SPBio_002985 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G18 compound treatment 297007.0 29000.0 0.59 297225.0 24100.0 0.5 0.7715 0.9969 3069780 SPBio_002986 OCCN1CCN(CC/C=C\2/c3ccccc3Sc4ccc(Cl)cc24)CC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G19 compound treatment 257955.0 -10000.0 -0.2 260622.0 -12500.0 -0.26 -0.3275 -0.9925 3221506 SPBio_002987 CCC(C)C(N)C1=NC(CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(=O)N)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G20 compound treatment 241632.0 -26300.0 -0.53 255833.0 -17300.0 -0.36 -0.632 -0.9815 4480 SPBio_002988 CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G21 compound treatment 249935.0 -18000.0 -0.37 283153.0 10000.0 0.21 -0.1106 -0.2624 1008 SPBio_002989 OC1CCCCC1N2CCC(CC2)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G22 compound treatment 305666.0 37700.0 0.76 287863.0 14800.0 0.31 0.7577 0.9199 3188032 SPBio_002990 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)NCNC(CCCCN)C(=O)O)C(=O)c4c(O)cccc4[C@@]3(C)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G23 mock treatment 264043.0 -3930.0 -0.08 289418.0 16300.0 0.34 0.184 0.5271 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 G24 mock treatment 244053.0 -23900.0 -0.48 246913.0 -26200.0 -0.55 -0.7287 -0.9983 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H01 mock treatment 266733.0 -1240.0 -0.03 253084.0 -20000.0 -0.42 -0.3127 -0.7484 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H02 mock treatment 299041.0 31100.0 0.63 262566.0 -10500.0 -0.22 0.2901 0.4349 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H03 compound treatment 303230.0 35300.0 0.71 325682.0 52600.0 1.1 1.2799 0.9786 3069853 SPBio_002991 OCN1C(NC(=O)NCNC(=O)NC2N(CO)C(=O)NC2=O)C(=O)NC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H04 mock treatment 278218.0 10200.0 0.21 300080.0 27000.0 0.56 0.5442 0.9084 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H05 compound treatment 307272.0 39300.0 0.8 298569.0 25500.0 0.53 0.9385 0.9805 1503 SPBio_002992 Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H06 mock treatment 291552.0 23600.0 0.48 301269.0 28200.0 0.59 0.7529 0.9948 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H07 compound treatment 4752.0 -263000.0 -5.34 26479.0 -247000.0 -5.14 -7.4064 -0.9998 834 SPBio_002993 CC(C[N+](C)(C)C)OC(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H08 mock treatment 278062.0 10100.0 0.2 289962.0 16900.0 0.35 0.3929 0.9669 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H09 compound treatment 278480.0 10500.0 0.21 311701.0 38600.0 0.8 0.7192 0.8646 3188277 SPBio_002994 CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)C5CC5[C@]4(C)[C@H]3CC[C@@]21C)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H10 mock treatment 303071.0 35100.0 0.71 316377.0 43300.0 0.9 1.1406 0.9931 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H11 compound treatment 279221.0 11200.0 0.23 317913.0 44800.0 0.93 0.8213 0.8547 1000206 SPBio_002995 CC(C)NC[C@@H](O)COc1cccc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H12 mock treatment 270636.0 2660.0 0.05 289961.0 16900.0 0.35 0.2865 0.8064 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H13 compound treatment 307973.0 40000.0 0.81 299844.0 26700.0 0.56 0.9673 0.9832 3903 SPBio_002996 CC(C)(Oc1ccc(cc1)C2CC2(Cl)Cl)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H14 mock treatment 265429.0 -2540.0 -0.05 283700.0 10600.0 0.22 0.1196 0.5277 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H15 compound treatment 297917.0 29900.0 0.61 291082.0 18000.0 0.37 0.6941 0.9731 1029881 SPBio_002997 CN1C2CCC1CC(O)C2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H16 mock treatment 254397.0 -13600.0 -0.28 303997.0 30900.0 0.64 0.2605 0.3721 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H17 compound treatment 2950.0 -265000.0 -5.37 2745.0 -270000.0 -5.63 -7.7818 -0.9997 954 SPBio_002998 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H18 mock treatment 284954.0 17000.0 0.34 280935.0 7830.0 0.16 0.3588 0.9418 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H19 compound treatment 276182.0 8210.0 0.17 283216.0 10100.0 0.21 0.2666 0.9932 1295 SPBio_002999 OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H20 mock treatment 245067.0 -22900.0 -0.46 276952.0 3850.0 0.08 -0.2717 -0.5766 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H21 compound treatment 269363.0 1390.0 0.03 292671.0 19600.0 0.41 0.3082 0.7542 3188278 SPBio_003000 COC(=O)Nc1nc2cc(SC(C)C)ccc2[nH]1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H22 mock treatment 282863.0 14900.0 0.3 281644.0 8540.0 0.18 0.3392 0.9682 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H23 mock treatment 271963.0 3990.0 0.08 268958.0 -4150.0 -0.09 -0.0039 -0.0329 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 H24 mock treatment 247241.0 -20700.0 -0.42 249013.0 -24100.0 -0.5 -0.6521 -0.9961 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I01 mock treatment 240130.0 -27800.0 -0.56 237637.0 -35500.0 -0.74 -0.9216 -0.9912 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I02 mock treatment 263296.0 -4680.0 -0.09 285860.0 12800.0 0.27 0.1209 0.4284 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I03 compound treatment 251135.0 -16800.0 -0.34 268926.0 -4180.0 -0.09 -0.3029 -0.8599 3188016 SPBio_003001 CN/C(=C\[N+](=O)[O-])/NCCSCc1csc(CN(C)C)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I04 compound treatment 254056.0 -13900.0 -0.28 306302.0 33200.0 0.69 0.2895 0.3876 3069781 SPBio_003002 CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I05 compound treatment 281117.0 13100.0 0.27 288804.0 15700.0 0.33 0.4197 0.9948 3188017 SPBio_003003 S=C(NC1CCCCC1)N2CCC(CC2)C3C=NC=N3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I06 compound treatment 270509.0 2540.0 0.05 294588.0 21500.0 0.45 0.3528 0.7832 3177333 SPBio_003004 CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I07 compound treatment 319590.0 51600.0 1.05 290949.0 17800.0 0.37 1.0028 0.903 3061617 SPBio_003005 OC(CNCCNC(=O)N1CCOCC1)COc2ccc(O)cc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I08 compound treatment 252353.0 -15600.0 -0.32 266033.0 -7070.0 -0.15 -0.3281 -0.9394 1053328 SPBio_003006 CCCC1C(=O)N2N(C1=O)c3cc(C)ccc3N=C2N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I09 compound treatment 281442.0 13500.0 0.27 322586.0 49500.0 1.03 0.922 0.8646 1000092 SPBio_003007 COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I10 compound treatment 268706.0 733.0 0.01 303926.0 30800.0 0.64 0.4645 0.7233 3188033 SPBio_003008 CCC1(CCCCN(C)C1)c2cccc(O)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I11 compound treatment 215598.0 -52400.0 -1.06 161660.0 -111000.0 -2.32 -2.3925 -0.9371 1007994 SPBio_003009 CCCCCCCCCCCCCCCC[N+](C)(C)CCN(Cc1ccc(OC)cc1)c2ncccn2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I12 compound treatment 50982.0 -217000.0 -4.4 144040.0 -129000.0 -2.69 -5.0119 -0.9721 3188034 SPBio_003010 CNC1C(O)C2O[C@H](OC3C(N)C[C@@H](N)C(O)[C@H]3O)C(N)C[C@@H]2O[C@@H]1O[C@H]4OC(CO)[C@@H](N)[C@H](O)C4O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I13 compound treatment 290201.0 22200.0 0.45 312839.0 39700.0 0.83 0.904 0.9591 3060036 SPBio_003011 C1CN=C(N1)C2COc3ccccc3O2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I14 compound treatment 215515.0 -52500.0 -1.06 255055.0 -18100.0 -0.38 -1.0179 -0.9024 3069782 SPBio_003012 C[C@@]12CC[C@H]3[C@@H](CC[C@H]4CC5SC5C[C@@]43C)[C@@H]2CC[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I15 compound treatment 325671.0 57700.0 1.17 299335.0 26200.0 0.55 1.2135 0.9399 3188018 SPBio_003013 CCN(CC)C(=O)N[C@@H]1CC2C(Cc3c[nH]c4cccc2c34)N(C)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I16 compound treatment 246504.0 -21500.0 -0.44 317999.0 44900.0 0.94 0.3536 0.3428 3188035 SPBio_003014 C/C(=C(/CCO)\SSCC1CCCO1)/N(Cc2cnc(C)nc2N)C=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I17 compound treatment 304308.0 36300.0 0.74 260069.0 -13000.0 -0.27 0.3288 0.4188 1765 SPBio_003015 CC1(C)NC(=O)N(C1=O)c2ccc([N+](=O)[O-])c(c2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I18 compound treatment 301184.0 33200.0 0.67 278164.0 5060.0 0.11 0.5506 0.808 2080 SPBio_003016 CCOC(=O)c1ccc(OC(=O)CCCCCNC(=N)N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I19 compound treatment 261252.0 -6720.0 -0.14 340093.0 67000.0 1.4 0.8905 0.6351 3172846 SPBio_003017 NC(CO)(CO)CO.OC(=O)C1CCn2c(ccc12)C(=O)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I20 compound treatment 291837.0 23900.0 0.48 268704.0 -4400.0 -0.09 0.2773 0.5631 3188145 SPBio_003018 CC(C)(C)C(=O)OCOC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](NC(=O)[C@H](N)c3ccccc3)C2=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I21 compound treatment 283601.0 15600.0 0.32 290042.0 16900.0 0.35 0.4735 0.9986 4487 SPBio_003019 CNCCCC1c2ccccc2C=Cc3ccccc13 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I22 compound treatment 3379.0 -265000.0 -5.36 2338.0 -271000.0 -5.64 -7.7817 -0.9997 3188146 SPBio_003020 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)OC4OC(=O)c5ccccc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I23 mock treatment 241121.0 -26900.0 -0.54 271108.0 -2000.0 -0.04 -0.4143 -0.7589 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 I24 mock treatment 230471.0 -37500.0 -0.76 258297.0 -14800.0 -0.31 -0.7557 -0.9211 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J01 mock treatment 262495.0 -5480.0 -0.11 242629.0 -30500.0 -0.63 -0.5275 -0.8184 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J02 mock treatment 273456.0 5480.0 0.11 297666.0 24600.0 0.51 0.4404 0.8411 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J03 compound treatment 293335.0 25400.0 0.51 288015.0 14900.0 0.31 0.5832 0.9709 3002368 SPBio_003021 CC(C)NC[C@H](O)COc1cccc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J04 mock treatment 315192.0 47200.0 0.96 317544.0 44400.0 0.93 1.3315 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J05 compound treatment 264343.0 -3630.0 -0.07 280227.0 7120.0 0.15 0.0529 0.3193 907302 SPBio_003022 CN1CC[C@]2(C)C1N(C)c3ccc(O)cc32 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J06 mock treatment 305522.0 37500.0 0.76 334778.0 61700.0 1.28 1.4468 0.9688 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J07 compound treatment 327059.0 59100.0 1.2 343134.0 70000.0 1.46 1.8786 0.9952 3188279 SPBio_003023 CCN1C[C@]2(COC)CC[C@H](O)C3(C4C[C@H]5[C@H](OC(=O)C)C4[C@](O)(CC5OC)[C@H]6CC32)[C@@H]61 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J08 mock treatment 285449.0 17500.0 0.35 319051.0 45900.0 0.96 0.9274 0.9086 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J09 compound treatment 287444.0 19500.0 0.39 321672.0 48600.0 1.01 0.9946 0.9158 2060476 SPBio_003024 C[C@H]1[C@@H]2CCC(=C3[C@@H]([C@H]2OC1=O)C(=CC3=O)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J10 mock treatment 324784.0 56800.0 1.15 338223.0 65100.0 1.36 1.7737 0.9967 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J11 compound treatment 311165.0 43200.0 0.88 315267.0 42200.0 0.88 1.2403 1.0 1336284 SPBio_003025 COc1c2CC(Oc2nc3ccccc13)C(C)(O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J12 mock treatment 309623.0 41700.0 0.84 313355.0 40200.0 0.84 1.19 1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J13 compound treatment 302602.0 34600.0 0.7 307059.0 34000.0 0.71 0.9966 1.0 3176921 SPBio_003026 N[C@H]1CONC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J14 mock treatment 286135.0 18200.0 0.37 331051.0 57900.0 1.21 1.114 0.8826 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J15 compound treatment 294100.0 26100.0 0.53 335036.0 61900.0 1.29 1.2868 0.9227 3069855 SPBio_003027 Clc1cnccn1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J16 mock treatment 281686.0 13700.0 0.28 314905.0 41800.0 0.87 0.8123 0.8887 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J17 compound treatment 316273.0 48300.0 0.98 261751.0 -11400.0 -0.24 0.5251 0.5213 1076620 SPBio_003028 CNCC(O)c1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J18 mock treatment 297250.0 29300.0 0.59 295655.0 22500.0 0.47 0.7519 0.9933 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J19 compound treatment 274103.0 6130.0 0.12 311037.0 37900.0 0.79 0.6467 0.8084 760 SPBio_003029 N[C@@H]1CONC1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J20 mock treatment 307925.0 40000.0 0.81 297605.0 24500.0 0.51 0.9336 0.9752 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J21 compound treatment 265779.0 -2190.0 -0.04 265641.0 -7460.0 -0.16 -0.1414 -0.8743 1076027 SPBio_003030 CC1CC(CC(C)(C)C1)OC(=O)c2ccccc2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J22 mock treatment 280454.0 12500.0 0.25 263404.0 -9700.0 -0.2 0.036 0.1112 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J23 mock treatment 275664.0 7690.0 0.16 263788.0 -9320.0 -0.19 -0.027 -0.1084 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 J24 mock treatment 252650.0 -15300.0 -0.31 241392.0 -31700.0 -0.66 -0.6868 -0.9408 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K01 mock treatment 279274.0 11300.0 0.23 285750.0 12600.0 0.26 0.3483 0.9976 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K02 mock treatment 269420.0 1450.0 0.03 286004.0 12900.0 0.27 0.2108 0.7797 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K03 compound treatment 278218.0 10200.0 0.21 288928.0 15800.0 0.33 0.38 0.9752 1677 SPBio_003031 CC(C)c1cccc(C(C)C)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K04 compound treatment 2306.0 -266000.0 -5.39 3347.0 -270000.0 -5.62 -7.7822 -0.9998 3188147 SPBio_003032 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)C(N3C2=O)C(=O)O)c4c(F)cccc4Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K05 compound treatment 292509.0 24500.0 0.5 308718.0 35600.0 0.74 0.8763 0.9811 3188019 SPBio_003033 CCN1CCCC1CNC(=O)c2c(O)c(CC)cc(Cl)c2OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K06 compound treatment 295079.0 27100.0 0.55 296025.0 22900.0 0.48 0.7262 0.9975 2920 SPBio_003034 CCN(CC)c1cc(C)nc2ncnn12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K07 compound treatment 313542.0 45600.0 0.92 308524.0 35400.0 0.74 1.175 0.9938 962 SPBio_003035 CCC1(C(=O)NCNC1=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K08 compound treatment 266992.0 -981.0 -0.02 296276.0 23200.0 0.48 0.3273 0.6774 3188148 SPBio_003036 CN1C2CCC1CC(C2)OC3c4ccccc4CCc5ccccc35 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K09 compound treatment 266011.0 -1960.0 -0.04 293049.0 19900.0 0.42 0.2657 0.6365 1910 SPBio_003037 Nc1nc(=O)[nH]cc1F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K10 compound treatment 256749.0 -11200.0 -0.23 260322.0 -12800.0 -0.27 -0.3492 -0.9969 3069806 SPBio_003038 OCCOCCOC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K11 compound treatment 286119.0 18100.0 0.37 313795.0 40700.0 0.85 0.8595 0.9302 3069740 SPBio_003039 C[C@]1(N[C@H]2Cc3ccccc31)c4ccccc24 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K12 compound treatment 204524.0 -63400.0 -1.29 302432.0 29300.0 0.61 -0.4775 -0.3353 1022844 SPBio_003040 Oc1ccc(O)c(c1)S(=O)(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K13 compound treatment 250231.0 -17700.0 -0.36 280494.0 7390.0 0.15 -0.1455 -0.3719 3188020 SPBio_003041 C[N+](C)(CCCOc1ccccc1)c2ccccc2.OC(=O)c1cc2ccccc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K14 compound treatment 271119.0 3150.0 0.06 321919.0 48800.0 1.02 0.7642 0.75 1779 SPBio_003042 COc1nc(C)nc(Cl)c1NC2=NCCN2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K15 compound treatment 278334.0 10400.0 0.21 302136.0 29000.0 0.6 0.5762 0.9 3069741 SPBio_003043 CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CCC4=O)[C@@H]3CC=C2C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K16 compound treatment 273864.0 5890.0 0.12 291849.0 18700.0 0.39 0.3606 0.883 1326779 SPBio_003044 CCNCC(O)c1cccc(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K17 compound treatment 265813.0 -2160.0 -0.04 283177.0 10100.0 0.21 0.1174 0.5478 1095 SPBio_003045 NC(CO)C(=O)NNCc1ccc(O)c(O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K18 compound treatment 283768.0 15800.0 0.32 274389.0 1280.0 0.03 0.2453 0.7635 220 SPBio_003046 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K19 compound treatment 287690.0 19700.0 0.4 270027.0 -3080.0 -0.06 0.2373 0.5862 2685 SPBio_003047 OC(=O)c1c(I)cc(I)c(NC(=O)CCCCC(=O)Nc2c(I)cc(I)c(C(=O)O)c2I)c1I 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K20 compound treatment 221846.0 -46100.0 -0.94 200036.0 -73100.0 -1.52 -1.7376 -0.9726 3188149 SPBio_003048 CCO[C@@H]1O[C@H](C(COCc2ccccc2)OCc3ccccc3)[C@@H](OCc4ccccc4)C1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K21 compound treatment 220061.0 -47900.0 -0.97 255389.0 -17700.0 -0.37 -0.9478 -0.9122 1020463 SPBio_003049 Oc1cc2ccc(=O)oc2cc1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K22 compound treatment 258090.0 -9880.0 -0.2 261605.0 -11500.0 -0.24 -0.3111 -0.996 3188150 SPBio_003050 CCC(=O)[C@@]1(C)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K23 mock treatment 291078.0 23100.0 0.47 254217.0 -18900.0 -0.39 0.053 0.0866 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 K24 mock treatment 249231.0 -18700.0 -0.38 241238.0 -31900.0 -0.66 -0.7381 -0.9649 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L01 mock treatment 265394.0 -2580.0 -0.05 279548.0 6440.0 0.13 0.0579 0.4023 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L02 mock treatment 261067.0 -6910.0 -0.14 282636.0 9530.0 0.2 0.0414 0.1704 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L03 compound treatment 324936.0 57000.0 1.15 302463.0 29400.0 0.61 1.249 0.9558 1269 SPBio_003051 CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L04 mock treatment 277755.0 9780.0 0.2 303153.0 30000.0 0.63 0.5829 0.8876 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L05 compound treatment 283693.0 15700.0 0.32 303470.0 30400.0 0.63 0.6727 0.9496 3069858 SPBio_003052 Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(=O)(O)O[C@@H]4C3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L06 mock treatment 10130.0 -258000.0 -5.23 28186.0 -245000.0 -5.1 -7.3041 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L07 compound treatment 279413.0 11400.0 0.23 392487.0 119000.0 2.49 1.9226 0.7697 907479 SPBio_003053 CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@H]21 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L08 mock treatment 316371.0 48400.0 0.98 298360.0 25300.0 0.53 1.0658 0.9573 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L09 compound treatment 160626.0 -107000.0 -2.18 117759.0 -155000.0 -3.24 -3.8272 -0.9814 3188280 SPBio_003054 COc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L10 mock treatment 311575.0 43600.0 0.88 306093.0 33000.0 0.69 1.111 0.9923 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L11 compound treatment 309281.0 41300.0 0.84 299090.0 26000.0 0.54 0.9749 0.9777 1221 SPBio_003055 CN(C)CCOC(=O)C(c1ccccc1)C2(O)CCCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L12 mock treatment 300012.0 32000.0 0.65 306672.0 33600.0 0.7 0.9538 0.9993 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L13 compound treatment 19901.0 -248000.0 -5.03 57809.0 -215000.0 -4.49 -6.7277 -0.9984 3188281 SPBio_003056 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2C[C@@H](O)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L14 mock treatment 295579.0 27600.0 0.56 269621.0 -3480.0 -0.07 0.3444 0.6103 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L15 compound treatment 292860.0 24900.0 0.5 274525.0 1420.0 0.03 0.3777 0.7473 1479 SPBio_003057 CC(C)NCC(O)c1ccc(O)c(O)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L16 mock treatment 284498.0 16500.0 0.34 269032.0 -4070.0 -0.08 0.1769 0.5118 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L17 compound treatment 300080.0 32100.0 0.65 300186.0 27100.0 0.56 0.8592 0.9975 2121 SPBio_003058 Oc1ccc(cc1)c2oc3cc(O)cc(O)c3c(=O)c2O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L18 mock treatment 255025.0 -12900.0 -0.26 300383.0 27300.0 0.57 0.2162 0.3454 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L19 compound treatment 222855.0 -45100.0 -0.91 222559.0 -50500.0 -1.05 -1.3914 -0.9975 865102 SPBio_003059 O=C(CCNNC(=O)c1ccncc1)NCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L20 mock treatment 268372.0 399.0 0.01 278936.0 5830.0 0.12 0.0916 0.7526 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L21 compound treatment 245514.0 -22500.0 -0.46 333270.0 60200.0 1.25 0.5643 0.4232 3188282 SPBio_003060 CC1C(C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)C(=O)c2ccccc2C1=O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L22 mock treatment 241694.0 -26300.0 -0.53 289128.0 16000.0 0.33 -0.1407 -0.2238 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L23 mock treatment 258032.0 -9940.0 -0.2 286306.0 13200.0 0.28 0.052 0.1524 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 L24 mock treatment 253850.0 -14100.0 -0.29 249756.0 -23300.0 -0.49 -0.5464 -0.9681 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M01 mock treatment 260036.0 -7940.0 -0.16 296110.0 23000.0 0.48 0.2251 0.4453 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M02 mock treatment 297661.0 29700.0 0.6 257690.0 -15400.0 -0.32 0.1985 0.291 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M03 compound treatment 303023.0 35100.0 0.71 319766.0 46700.0 0.97 1.1898 0.9881 2030 SPBio_003061 OC(=O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M04 compound treatment 309729.0 41800.0 0.85 308268.0 35200.0 0.73 1.1166 0.9974 3480040 SPBio_003062 COC(=O)C1=C(C)NC(=C(C1c2cccc3nonc23)C(=O)OC(C)C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M05 compound treatment 298550.0 30600.0 0.62 301734.0 28600.0 0.6 0.8601 0.9998 907192 SPBio_003063 CC[N+](C)(C)Cc1ccccc1Br 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M06 compound treatment 271102.0 3130.0 0.06 285305.0 12200.0 0.25 0.2246 0.8573 1077199 SPBio_003064 CCNC1(CCCCC1=O)c2cccs2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M07 compound treatment 294958.0 27000.0 0.55 315103.0 42000.0 0.87 1.0055 0.9744 3172714 SPBio_003065 C[n+]1ccccc1/C=N/O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M08 compound treatment 295255.0 27300.0 0.55 318040.0 44900.0 0.94 1.053 0.9685 3069807 SPBio_003066 CNC(C)CCC=C(C)C.OC(C(O)C(O)C(=O)O)C(O)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M09 compound treatment 315507.0 47500.0 0.96 283495.0 10400.0 0.22 0.8345 0.8449 1395 SPBio_003067 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M10 compound treatment 239477.0 -28500.0 -0.58 221313.0 -51800.0 -1.08 -1.1714 -0.9571 3188151 SPBio_003068 CC1CS(=O)(=O)CCN1/N=C/c2ccc(o2)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M11 compound treatment 305938.0 38000.0 0.77 276049.0 2940.0 0.06 0.5876 0.761 2844 SPBio_003069 CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M12 compound treatment 289787.0 21800.0 0.44 268179.0 -4930.0 -0.1 0.2401 0.529 1698 SPBio_003070 N#Cc1ccc(cc1)C(c2ccc(C#N)cc2)n3cncn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M13 compound treatment 284502.0 16500.0 0.34 290427.0 17300.0 0.36 0.4921 0.9993 1371 SPBio_003071 CN(C)c1nc(nc(n1)N(C)C)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M14 compound treatment 271843.0 3870.0 0.08 265105.0 -8000.0 -0.17 -0.0624 -0.3386 4425 SPBio_003072 CC(C)NCC1CCc2cc(CO)c(cc2N1)[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M15 compound treatment 321909.0 53900.0 1.09 326043.0 52900.0 1.1 1.553 1.0 349 SPBio_003073 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M16 compound treatment 317585.0 49600.0 1.01 284625.0 11500.0 0.24 0.8809 0.8519 3188152 SPBio_003074 CC(N)C(=O)Nc1c(C)cccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M17 compound treatment 270349.0 2380.0 0.05 279149.0 6040.0 0.13 0.1231 0.9131 1428570 SPBio_003075 CC(C)(C)NC[C@H](O)COc1nsnc1N2CCOCC2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M18 compound treatment 6591.0 -261000.0 -5.3 3079.0 -270000.0 -5.63 -7.7247 -0.9996 3188153 SPBio_003076 CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2C1C(=O)O.C(CNCc1ccccc1)NCc2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M19 compound treatment 268339.0 366.0 0.01 267315.0 -5790.0 -0.12 -0.08 -0.6623 893 SPBio_003077 NCC(O)c1ccc(O)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M20 compound treatment 258310.0 -9660.0 -0.2 235085.0 -38000.0 -0.79 -0.6986 -0.8562 1795 SPBio_003078 Cc1nc2CCCCn2c(=O)c1CCN3CCC(CC3)c4noc5cc(F)ccc45 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M21 compound treatment 272081.0 4110.0 0.08 265960.0 -7150.0 -0.15 -0.0464 -0.2718 806 SPBio_003079 OC(=O)C1CCCNC1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M22 compound treatment 251138.0 -16800.0 -0.34 283598.0 10500.0 0.22 -0.0868 -0.2141 1001638 SPBio_003080 CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc2cccc(C)c2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M23 mock treatment 253598.0 -14400.0 -0.29 266711.0 -6390.0 -0.13 -0.3003 -0.9371 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 M24 mock treatment 240703.0 -27300.0 -0.55 236415.0 -36700.0 -0.76 -0.9314 -0.9873 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N01 mock treatment 276406.0 8430.0 0.17 305016.0 31900.0 0.66 0.591 0.8609 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N02 mock treatment 351788.0 83800.0 1.7 338674.0 65600.0 1.37 2.1674 0.9941 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N03 compound treatment 299340.0 31400.0 0.64 311440.0 38300.0 0.8 1.0144 0.9936 3487604 SPBio_003081 CCNC1CC(N)C(OC2OC(=CCC2N)CN)C(O)C1OC3OCC(C)(O)C(NC)C3O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N04 mock treatment 289591.0 21600.0 0.44 316040.0 42900.0 0.89 0.9424 0.9461 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N05 compound treatment 347206.0 79200.0 1.61 315881.0 42800.0 0.89 1.766 0.9614 3173761 SPBio_003082 N[C@@H](C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)Cl)c3ccccc3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N06 mock treatment 305828.0 37900.0 0.77 330196.0 57100.0 1.19 1.3837 0.9775 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N07 compound treatment 284590.0 16600.0 0.34 320717.0 47600.0 0.99 0.9396 0.8969 1111897 SPBio_003083 COc1ccc2nccc(C(=O)O)c2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N08 mock treatment 325168.0 57200.0 1.16 320638.0 47500.0 0.99 1.5201 0.9969 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N09 compound treatment 285929.0 18000.0 0.36 319521.0 46400.0 0.97 0.9412 0.9109 3188283 SPBio_003084 CC1O[C@@H](OC/2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(=O)O)C[C@@H](O)C[C@H]4O[C@@H]4\C=C\C(=O)O[C@H](C)C\C=C\C=C\C=C\C=C2)C(O)C(N)[C@@H]1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N10 mock treatment 291971.0 24000.0 0.49 268634.0 -4470.0 -0.09 0.2782 0.5615 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N11 compound treatment 32555.0 -235000.0 -4.77 47225.0 -226000.0 -4.71 -6.7022 -1.0 3188284 SPBio_003085 COC(=O)CCc1c(C)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(CCC(=O)O)c5C)[C@]6(C)C(C(=O)OC)C(=CC=C46)C(=O)OC)c(C)c3C=C.COC(=O)CCc1c(C)c2cc3nc(cc4[nH]c(cc5nc(cc1[nH]2)c(CCC(=O)O)c5C)c(C=C)c4C)C6=CC=C(C(C(=O)OC)[C@]63C)C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N12 mock treatment 300715.0 32700.0 0.66 251759.0 -21300.0 -0.44 0.1549 0.1939 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N13 compound treatment 2257.0 -266000.0 -5.39 3045.0 -270000.0 -5.63 -7.7874 -0.9998 1000348 SPBio_003086 C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(=C(N2C1=O)C(=O)O)S[C@@H]3CN[C@@H](C3)C(=O)N(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N14 mock treatment 293488.0 25500.0 0.52 284290.0 11200.0 0.23 0.5305 0.9351 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N15 compound treatment 256268.0 -11700.0 -0.24 305149.0 32000.0 0.67 0.3043 0.4294 3069861 SPBio_003087 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2C(C[C@@H]3CCC[C@@H]32)C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N16 mock treatment 288028.0 20100.0 0.41 286387.0 13300.0 0.28 0.4831 0.9824 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N17 compound treatment 267585.0 -388.0 -0.01 294228.0 21100.0 0.44 0.3056 0.6944 1517 SPBio_003088 CCC1(NC(=O)N(C)C1=O)c2ccccc2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N18 mock treatment 270914.0 2940.0 0.06 274330.0 1220.0 0.03 0.0602 0.9283 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N19 compound treatment 2447.0 -266000.0 -5.38 2747.0 -270000.0 -5.63 -7.789 -0.9997 3188285 SPBio_003089 CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c4C5=NC6(CCN(CC(C)C)CC6)NC5=C(NC(=O)/C(=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(=O)C)[C@@H]1C)/C)C(=O)c4c(O)c3C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N20 mock treatment 306911.0 38900.0 0.79 291073.0 18000.0 0.37 0.8229 0.9419 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N21 compound treatment 273446.0 5470.0 0.11 254484.0 -18600.0 -0.39 -0.1959 -0.4854 3069862 SPBio_003090 CCCCc1ccc2[nH]c(NC(=O)OC)nc2c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N22 mock treatment 252791.0 -15200.0 -0.31 256976.0 -16100.0 -0.34 -0.4552 -0.999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N23 mock treatment 249345.0 -18600.0 -0.38 255091.0 -18000.0 -0.38 -0.5324 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 N24 mock treatment 234359.0 -33600.0 -0.68 241270.0 -31800.0 -0.66 -0.9508 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O01 mock treatment 249253.0 -18700.0 -0.38 272335.0 -770.0 -0.02 -0.2797 -0.7363 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O02 mock treatment 261587.0 -6390.0 -0.13 276212.0 3110.0 0.06 -0.0458 -0.3163 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O03 compound treatment 288399.0 20400.0 0.41 263881.0 -9220.0 -0.19 0.1569 0.3438 2660 SPBio_003091 CCN(C(=O)/C=C/C)c1ccccc1C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O04 compound treatment 273975.0 6000.0 0.12 258865.0 -14200.0 -0.3 -0.1237 -0.3859 2080909 SPBio_003092 CCCCN(CCCC)CCC(O)c1cc2c(Cl)cc(Cl)cc2c3cc(ccc13)C(F)(F)F 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O05 compound treatment 263120.0 -4850.0 -0.1 298389.0 25300.0 0.53 0.3029 0.5653 351 SPBio_003093 CC(C)NCC(O)COc1cccc2ccccc12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O06 compound treatment 270838.0 2870.0 0.06 255896.0 -17200.0 -0.36 -0.2124 -0.5849 3069809 SPBio_003094 CCCNC(C)C(=O)Nc1c(C)csc1C(=O)OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O07 compound treatment 294162.0 26200.0 0.53 266105.0 -7000.0 -0.15 0.2723 0.4946 1001857 SPBio_003095 CC(C)NC[C@@H](O)COc1ccc(CC(=O)N)cc1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O08 compound treatment 280868.0 12900.0 0.26 266735.0 -6370.0 -0.13 0.091 0.3104 3188154 SPBio_003096 CC(=O)CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@@H]4[C@H]3CC[C@@]21C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O09 compound treatment 194688.0 -73300.0 -1.49 175418.0 -97700.0 -2.04 -2.4896 -0.988 3188022 SPBio_003097 CC(C)(C)CC(C)(C)c1ccc(OCOCCOCCO)c(Cc2cc(cc(Cc3cc(ccc3OCOCCOCCO)C(C)(C)CC(C)(C)C)c2OCOCCOCCO)C(C)(C)CC(C)(C)C)c1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O10 compound treatment 269775.0 1800.0 0.04 275316.0 2210.0 0.05 0.0584 0.9934 3177327 SPBio_003098 CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(=O)C)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)[N+]5(C)CCCCC5)[N+]6(C)CCCCC6 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O11 compound treatment 3143.0 -265000.0 -5.37 2695.0 -270000.0 -5.63 -7.7798 -0.9997 3069742 SPBio_003099 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O12 compound treatment 271761.0 3790.0 0.08 244459.0 -28600.0 -0.6 -0.3677 -0.6111 1511611 SPBio_003100 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O13 compound treatment 292778.0 24800.0 0.5 304440.0 31300.0 0.65 0.8172 0.9917 4369 SPBio_003101 CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C)C(=O)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O14 compound treatment 250557.0 -17400.0 -0.35 284035.0 10900.0 0.23 -0.0886 -0.211 3188155 SPBio_003102 OC/C=C\1/[C@@H]2C[C@@H]3[C@@H](CC[C@]34C5N(C=C6C7N(C=C52)c8ccccc8[C@]97CC[C@@H]%10[C@H]9C[C@H]6\C(=C\CO)\N%10CC=C)c%11ccccc%114)N1CC=C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O15 compound treatment 252027.0 -15900.0 -0.32 273441.0 336.0 0.01 -0.2236 -0.6916 3069771 SPBio_003103 C[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]2CC[C@@H]1C(=O)CO 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O16 compound treatment 263958.0 -4010.0 -0.08 274502.0 1400.0 0.03 -0.037 -0.4278 2747 SPBio_003104 Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O17 compound treatment 256261.0 -11700.0 -0.24 268000.0 -5110.0 -0.11 -0.2431 -0.9344 1000212 SPBio_003105 C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O18 compound treatment 255763.0 -12200.0 -0.25 255185.0 -17900.0 -0.37 -0.439 -0.9801 3069810 SPBio_003106 COc1ccc(C[C@](C)(N)C(=O)O)cc1OC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O19 compound treatment 251402.0 -16600.0 -0.34 257250.0 -15900.0 -0.33 -0.4711 -1.0 4481 SPBio_003107 CCCOc1ccc(cc1N)C(=O)OCCN(CC)CC 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O20 compound treatment 267224.0 -749.0 -0.02 280467.0 7360.0 0.15 0.0977 0.634 3069811 SPBio_003108 C[C@@H]1CN(CC[C@]1(C(=O)O)c2ccccc2)[C@H]3CC[C@](CC3)(C#N)c4ccc(F)cc4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O21 compound treatment 233204.0 -34800.0 -0.7 267290.0 -5820.0 -0.12 -0.5841 -0.8167 1167 SPBio_003109 NCCCCCC(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O22 compound treatment 204012.0 -64000.0 -1.3 137374.0 -136000.0 -2.83 -2.9164 -0.9375 3188156 SPBio_003110 CN(C)c1ccc2[n+](C)c(/C=C\c3cc(C)n(c3C)c4ccccc4)ccc2c1.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O23 mock treatment 249988.0 -18000.0 -0.36 247347.0 -25800.0 -0.54 -0.6373 -0.9823 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 O24 mock treatment 255169.0 -12800.0 -0.26 277117.0 4010.0 0.08 -0.1244 -0.4564 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P01 mock treatment 272714.0 4740.0 0.1 257507.0 -15600.0 -0.32 -0.1618 -0.4775 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P02 mock treatment 283973.0 16000.0 0.32 258924.0 -14200.0 -0.3 0.0205 0.0466 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P03 compound treatment 298615.0 30600.0 0.62 269435.0 -3670.0 -0.08 0.3852 0.6154 3856 SPBio_003111 CNC1(C)C2CCC(C2)C1(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P04 mock treatment 288668.0 20700.0 0.42 283638.0 10500.0 0.22 0.4518 0.9543 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P05 compound treatment 302381.0 34400.0 0.7 314411.0 41300.0 0.86 1.1017 0.9946 3199 SPBio_003112 CNNCc1ccc(cc1)C(=O)NC(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P06 mock treatment 271321.0 3350.0 0.07 258706.0 -14400.0 -0.3 -0.1641 -0.5336 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P07 compound treatment 282109.0 14100.0 0.29 273659.0 554.0 0.01 0.2108 0.735 3188286 SPBio_003113 NCCCC(N)CC(=O)NC1CNC(=O)C(NC(=O)/C(=C/NC(=O)N)/NC(=O)C(CO)NC(=O)C(CO)NC1=O)C2CC(O)N=C(N)N2 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P08 mock treatment 276355.0 8380.0 0.17 254753.0 -18400.0 -0.38 -0.1502 -0.359 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P09 compound treatment 273302.0 5330.0 0.11 289920.0 16800.0 0.35 0.3241 0.8841 3069863 SPBio_003114 CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@@H](O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(=O)N)NC(=O)c4ccc5ccccc5n4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P10 mock treatment 279307.0 11300.0 0.23 282873.0 9770.0 0.2 0.3064 0.9982 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P11 compound treatment 159160.0 -109000.0 -2.21 188980.0 -84100.0 -1.75 -2.7991 -0.9935 1509 SPBio_003115 Cn1c(COC(=O)N)ncc1[N+](=O)[O-] 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P12 mock treatment 274017.0 6040.0 0.12 283183.0 10100.0 0.21 0.2351 0.9671 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P13 compound treatment 258463.0 -9510.0 -0.19 277575.0 4470.0 0.09 -0.0705 -0.3292 1829 SPBio_003116 CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(=O)(=O)N 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P14 mock treatment 225858.0 -42100.0 -0.85 248759.0 -24300.0 -0.51 -0.9624 -0.9691 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P15 compound treatment 255624.0 -12300.0 -0.25 267845.0 -5260.0 -0.11 -0.2545 -0.9313 1078453 SPBio_003117 Fc1ccc(cc1)C(=O)CCCN2CCN(CC2)c3ccccn3 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P16 mock treatment 235176.0 -32800.0 -0.66 262043.0 -11100.0 -0.23 -0.6331 -0.8997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P17 compound treatment 95449.0 -173000.0 -3.5 35026.0 -238000.0 -4.96 -5.9803 -0.9854 3188288 SPBio_003118 CO/N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)C[N+]3(C)CCCC3)\c4csc(N)n4 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P18 mock treatment 239392.0 -28600.0 -0.58 250290.0 -22800.0 -0.48 -0.7458 -0.9952 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P19 compound treatment 241420.0 -26600.0 -0.54 276015.0 2910.0 0.06 -0.3378 -0.6235 3188289 SPBio_003119 C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@H]1C(=O)COC(=O)C(C)(C)C 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P20 mock treatment 233880.0 -34100.0 -0.69 244701.0 -28400.0 -0.59 -0.9071 -0.997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P21 compound treatment 11673.0 -256000.0 -5.2 8086.0 -265000.0 -5.52 -7.5781 -0.9995 2884 SPBio_003120 CC1(C)S[C@@H]2[C@H](NC(=O)C3(N)CCCCC3)C(=O)N2[C@H]1C(=O)O 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P22 mock treatment 234471.0 -33500.0 -0.68 271573.0 -1530.0 -0.03 -0.5028 -0.7395 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P23 mock treatment 232004.0 -36000.0 -0.73 256361.0 -16700.0 -0.35 -0.7623 -0.943 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.2167 P24 mock treatment 231937.0 -36000.0 -0.73 257526.0 -15600.0 -0.32 -0.7461 -0.9333 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A01 mock treatment 235743.0 -38000.0 -0.77 221131.0 -56900.0 -1.18 -1.383 -0.9784 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A02 mock treatment 237076.0 -36700.0 -0.74 238751.0 -39200.0 -0.82 -1.1043 -0.9989 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A03 mock treatment 233762.0 -40000.0 -0.81 240894.0 -37100.0 -0.77 -1.1202 -0.9997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A04 mock treatment 268659.0 -5130.0 -0.1 245718.0 -32300.0 -0.67 -0.5489 -0.8069 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A05 mock treatment 229992.0 -43800.0 -0.89 237290.0 -40700.0 -0.85 -1.2274 -0.9997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A06 mock treatment 255350.0 -18400.0 -0.37 257875.0 -20100.0 -0.42 -0.5606 -0.9984 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A07 mock treatment 245662.0 -28100.0 -0.57 269176.0 -8810.0 -0.18 -0.533 -0.8898 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A08 mock treatment 252798.0 -21000.0 -0.43 224286.0 -53700.0 -1.12 -1.092 -0.9123 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A09 mock treatment 240924.0 -32900.0 -0.67 234819.0 -43200.0 -0.9 -1.107 -0.9891 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A10 mock treatment 3671.0 -270000.0 -5.48 12724.0 -265000.0 -5.53 -7.7798 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A11 mock treatment 251643.0 -22100.0 -0.45 261281.0 -16700.0 -0.35 -0.5636 -0.9921 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A12 mock treatment 257737.0 -16100.0 -0.33 254544.0 -23400.0 -0.49 -0.5755 -0.9805 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A13 mock treatment 237195.0 -36600.0 -0.74 263671.0 -14300.0 -0.3 -0.7355 -0.9198 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A14 mock treatment 208060.0 -65700.0 -1.33 254660.0 -23300.0 -0.49 -1.2859 -0.9066 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A15 mock treatment 233031.0 -40800.0 -0.83 256263.0 -21700.0 -0.45 -0.9043 -0.9599 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A16 mock treatment 270585.0 -3200.0 -0.06 286548.0 8560.0 0.18 0.0802 0.4224 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A17 mock treatment 252613.0 -21200.0 -0.43 244094.0 -33900.0 -0.71 -0.8029 -0.9716 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A18 mock treatment 212692.0 -61100.0 -1.24 220306.0 -57700.0 -1.2 -1.7256 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A19 mock treatment 233022.0 -40800.0 -0.83 250615.0 -27400.0 -0.57 -0.9876 -0.9836 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A20 mock treatment 219133.0 -54700.0 -1.11 274599.0 -3390.0 -0.07 -0.8334 -0.7506 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A21 mock treatment 222872.0 -50900.0 -1.03 218050.0 -59900.0 -1.25 -1.6129 -0.9955 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A22 mock treatment 255407.0 -18400.0 -0.37 233112.0 -44900.0 -0.93 -0.9246 -0.9187 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A23 mock treatment 227791.0 -46000.0 -0.93 276115.0 -1870.0 -0.04 -0.687 -0.736 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base A24 mock treatment 224715.0 -49100.0 -0.99 226450.0 -51500.0 -1.07 -1.4627 -0.9993 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B01 mock treatment 246669.0 -27100.0 -0.55 249798.0 -28200.0 -0.59 -0.804 -0.9995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B02 mock treatment 258398.0 -15400.0 -0.31 260591.0 -17400.0 -0.36 -0.4769 -0.9972 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B03 mock treatment 249544.0 -24200.0 -0.49 268004.0 -9980.0 -0.21 -0.4946 -0.9268 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B04 mock treatment 273825.0 35.1 0.0 259446.0 -18500.0 -0.39 -0.2726 -0.7058 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B05 mock treatment 270465.0 -3320.0 -0.07 326263.0 48300.0 1.01 0.6635 0.6582 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B06 mock treatment 280770.0 6980.0 0.14 269130.0 -8860.0 -0.18 -0.0304 -0.1308 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B07 mock treatment 260897.0 -12900.0 -0.26 273094.0 -4890.0 -0.1 -0.2569 -0.9157 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B08 mock treatment 257014.0 -16800.0 -0.34 287939.0 9950.0 0.21 -0.0939 -0.2357 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B09 mock treatment 265905.0 -7880.0 -0.16 243969.0 -34000.0 -0.71 -0.6142 -0.8454 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B10 mock treatment 277001.0 3210.0 0.07 266594.0 -11400.0 -0.24 -0.1218 -0.4949 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B11 mock treatment 257867.0 -15900.0 -0.32 263896.0 -14100.0 -0.29 -0.4358 -0.9989 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B12 mock treatment 257649.0 -16100.0 -0.33 276884.0 -1100.0 -0.02 -0.2476 -0.7549 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B13 mock treatment 269473.0 -4320.0 -0.09 255167.0 -22800.0 -0.48 -0.398 -0.8234 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B14 mock treatment 255539.0 -18300.0 -0.37 256601.0 -21400.0 -0.45 -0.5767 -0.9957 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B15 mock treatment 247275.0 -26500.0 -0.54 277054.0 -933.0 -0.02 -0.3938 -0.7322 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B16 mock treatment 270978.0 -2810.0 -0.06 272903.0 -5080.0 -0.11 -0.1152 -0.9578 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B17 mock treatment 270142.0 -3650.0 -0.07 241927.0 -36100.0 -0.75 -0.5835 -0.773 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B18 mock treatment 249066.0 -24700.0 -0.5 249370.0 -28600.0 -0.6 -0.776 -0.9963 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B19 mock treatment 263829.0 -9960.0 -0.2 267859.0 -10100.0 -0.21 -0.292 -0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B20 mock treatment 247197.0 -26600.0 -0.54 266531.0 -11500.0 -0.24 -0.55 -0.9328 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B21 mock treatment 270842.0 -2950.0 -0.06 262066.0 -15900.0 -0.33 -0.2768 -0.8213 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B22 mock treatment 263644.0 -10100.0 -0.21 250480.0 -27500.0 -0.57 -0.5507 -0.9044 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B23 mock treatment 280422.0 6630.0 0.13 273418.0 -4570.0 -0.1 0.0278 0.1685 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base B24 mock treatment 246767.0 -27000.0 -0.55 250381.0 -27600.0 -0.58 -0.794 -0.9997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C01 mock treatment 230298.0 -43500.0 -0.88 242666.0 -35300.0 -0.74 -1.1438 -0.996 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C02 mock treatment 238958.0 -34800.0 -0.71 236193.0 -41800.0 -0.87 -1.115 -0.9946 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C03 mock treatment 165820.0 -108000.0 -2.19 174023.0 -104000.0 -2.17 -3.0793 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C04 mock treatment 181181.0 -92600.0 -1.88 276272.0 -1720.0 -0.04 -1.3528 -0.7204 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C05 mock treatment 293710.0 19900.0 0.4 291946.0 14000.0 0.29 0.4912 0.987 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C06 mock treatment 302958.0 29200.0 0.59 273826.0 -4160.0 -0.09 0.3568 0.5971 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C07 mock treatment 269212.0 -4580.0 -0.09 263711.0 -14300.0 -0.3 -0.2759 -0.8856 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C08 mock treatment 267551.0 -6240.0 -0.13 306146.0 28200.0 0.59 0.3254 0.5422 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C09 mock treatment 263222.0 -10600.0 -0.21 268130.0 -9860.0 -0.21 -0.2967 -0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C10 mock treatment 254253.0 -19500.0 -0.4 259747.0 -18200.0 -0.38 -0.5488 -0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C11 mock treatment 256179.0 -17600.0 -0.36 264177.0 -13800.0 -0.29 -0.4559 -0.9943 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C12 mock treatment 257802.0 -16000.0 -0.32 255456.0 -22500.0 -0.47 -0.5611 -0.9837 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C13 mock treatment 301206.0 27400.0 0.56 266453.0 -11500.0 -0.24 0.2231 0.3684 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C14 mock treatment 259745.0 -14000.0 -0.28 230057.0 -47900.0 -1.0 -0.9074 -0.8739 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C15 mock treatment 265824.0 -7970.0 -0.16 248948.0 -29000.0 -0.6 -0.542 -0.8656 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C16 mock treatment 272330.0 -1460.0 -0.03 268094.0 -9890.0 -0.21 -0.1667 -0.8004 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C17 mock treatment 262377.0 -11400.0 -0.23 246425.0 -31600.0 -0.66 -0.6285 -0.9017 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C18 mock treatment 251367.0 -22400.0 -0.45 264547.0 -13400.0 -0.28 -0.5194 -0.9729 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C19 mock treatment 259397.0 -14400.0 -0.29 236553.0 -41400.0 -0.86 -0.8167 -0.8963 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C20 mock treatment 268041.0 -5750.0 -0.12 249958.0 -28000.0 -0.58 -0.4953 -0.8318 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C21 mock treatment 275264.0 1470.0 0.03 261485.0 -16500.0 -0.34 -0.222 -0.6432 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C22 mock treatment 255778.0 -18000.0 -0.37 260667.0 -17300.0 -0.36 -0.5133 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C23 mock treatment 267583.0 -6210.0 -0.13 232919.0 -45100.0 -0.94 -0.7529 -0.7948 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base C24 mock treatment 257374.0 -16400.0 -0.33 228582.0 -49400.0 -1.03 -0.9631 -0.8904 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D01 mock treatment 230541.0 -43200.0 -0.88 253843.0 -24100.0 -0.5 -0.9756 -0.9652 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D02 mock treatment 242443.0 -31300.0 -0.64 240843.0 -37100.0 -0.77 -0.9965 -0.9952 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D03 mock treatment 264825.0 -8960.0 -0.18 273540.0 -4450.0 -0.09 -0.194 -0.9511 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D04 mock treatment 280197.0 6410.0 0.13 281204.0 3220.0 0.07 0.1392 0.9526 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D05 mock treatment 290190.0 16400.0 0.33 298973.0 21000.0 0.44 0.5442 0.9909 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D06 mock treatment 275318.0 1530.0 0.03 263972.0 -14000.0 -0.29 -0.1846 -0.6286 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D07 mock treatment 308369.0 34600.0 0.7 281015.0 3030.0 0.06 0.5403 0.7676 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D08 mock treatment 268438.0 -5350.0 -0.11 278106.0 119.0 0.0 -0.075 -0.6908 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D09 mock treatment 250598.0 -23200.0 -0.47 259340.0 -18600.0 -0.39 -0.6071 -0.9955 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D10 mock treatment 287731.0 13900.0 0.28 293280.0 15300.0 0.32 0.4251 0.9982 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D11 mock treatment 273316.0 -474.0 -0.01 263639.0 -14300.0 -0.3 -0.2182 -0.7295 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D12 mock treatment 283212.0 9420.0 0.19 259083.0 -18900.0 -0.39 -0.1434 -0.3276 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D13 mock treatment 277001.0 3210.0 0.07 271225.0 -6760.0 -0.14 -0.0536 -0.3453 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D14 mock treatment 242091.0 -31700.0 -0.64 275222.0 -2770.0 -0.06 -0.4951 -0.7674 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D15 mock treatment 284577.0 10800.0 0.22 280078.0 2090.0 0.04 0.1854 0.8316 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D16 mock treatment 251644.0 -22100.0 -0.45 268358.0 -9630.0 -0.2 -0.4593 -0.9341 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D17 mock treatment 254212.0 -19600.0 -0.4 275282.0 -2710.0 -0.06 -0.3205 -0.7995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D18 mock treatment 272592.0 -1200.0 -0.02 259008.0 -19000.0 -0.4 -0.2968 -0.7491 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D19 mock treatment 272941.0 -849.0 -0.02 245708.0 -32300.0 -0.67 -0.4877 -0.725 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D20 mock treatment 251776.0 -22000.0 -0.45 267092.0 -10900.0 -0.23 -0.4761 -0.9508 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D21 mock treatment 265421.0 -8370.0 -0.17 237893.0 -40100.0 -0.84 -0.7106 -0.8337 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D22 mock treatment 265702.0 -8090.0 -0.16 252235.0 -25800.0 -0.54 -0.4953 -0.8829 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D23 mock treatment 221119.0 -52700.0 -1.07 231367.0 -46600.0 -0.97 -1.4418 -0.9989 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base D24 mock treatment 241629.0 -32200.0 -0.65 234633.0 -43400.0 -0.9 -1.0997 -0.9872 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E01 mock treatment 249414.0 -24400.0 -0.49 225612.0 -52400.0 -1.09 -1.121 -0.9358 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E02 mock treatment 279683.0 5890.0 0.12 267632.0 -10400.0 -0.22 -0.0681 -0.276 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E03 mock treatment 293194.0 19400.0 0.39 292882.0 14900.0 0.31 0.4976 0.9931 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E04 mock treatment 266391.0 -7400.0 -0.15 292307.0 14300.0 0.3 0.1049 0.3141 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E05 mock treatment 336450.0 62700.0 1.27 255020.0 -23000.0 -0.48 0.5599 0.4125 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E06 mock treatment 261468.0 -12300.0 -0.25 281472.0 3480.0 0.07 -0.1253 -0.4817 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E07 mock treatment 287543.0 13800.0 0.28 267481.0 -10500.0 -0.22 0.0424 0.1196 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E08 mock treatment 252945.0 -20800.0 -0.42 291721.0 13700.0 0.29 -0.0965 -0.1891 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E09 mock treatment 280840.0 7050.0 0.14 294756.0 16800.0 0.35 0.3481 0.9222 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E10 mock treatment 284395.0 10600.0 0.21 248762.0 -29200.0 -0.61 -0.2785 -0.4313 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E11 mock treatment 283960.0 10200.0 0.21 281946.0 3960.0 0.08 0.2041 0.9192 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E12 mock treatment 293863.0 20100.0 0.41 283759.0 5770.0 0.12 0.3728 0.8785 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E13 mock treatment 278938.0 5150.0 0.1 292811.0 14800.0 0.31 0.2922 0.8963 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E14 mock treatment 260347.0 -13400.0 -0.27 286172.0 8180.0 0.17 -0.0721 -0.2244 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E15 mock treatment 299635.0 25800.0 0.52 258826.0 -19200.0 -0.4 0.0882 0.1339 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E16 mock treatment 263836.0 -9950.0 -0.2 296979.0 19000.0 0.4 0.1371 0.3086 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E17 mock treatment 308925.0 35100.0 0.71 286897.0 8910.0 0.19 0.6349 0.8626 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E18 mock treatment 279172.0 5380.0 0.11 279469.0 1480.0 0.03 0.099 0.8729 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E19 mock treatment 296679.0 22900.0 0.46 284169.0 6180.0 0.13 0.4192 0.8705 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E20 mock treatment 292924.0 19100.0 0.39 266567.0 -11400.0 -0.24 0.1061 0.2331 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E21 mock treatment 283136.0 9350.0 0.19 275393.0 -2590.0 -0.05 0.0958 0.486 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E22 mock treatment 270986.0 -2800.0 -0.06 260967.0 -17000.0 -0.35 -0.2909 -0.8101 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E23 mock treatment 277662.0 3870.0 0.08 281548.0 3560.0 0.07 0.108 0.9996 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base E24 mock treatment 262787.0 -11000.0 -0.22 244452.0 -33500.0 -0.7 -0.6517 -0.8887 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F01 mock treatment 265078.0 -8710.0 -0.18 238516.0 -39500.0 -0.82 -0.7063 -0.8398 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F02 mock treatment 289340.0 15600.0 0.32 265976.0 -12000.0 -0.25 0.046 0.1142 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F03 mock treatment 273102.0 -688.0 -0.01 291284.0 13300.0 0.28 0.186 0.6707 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F04 mock treatment 287262.0 13500.0 0.27 316183.0 38200.0 0.8 0.7558 0.8984 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F05 mock treatment 296725.0 22900.0 0.46 309097.0 31100.0 0.65 0.7871 0.9867 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F06 mock treatment 295877.0 22100.0 0.45 322342.0 44400.0 0.92 0.97 0.9447 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F07 mock treatment 268084.0 -5710.0 -0.12 298607.0 20600.0 0.43 0.222 0.4989 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F08 mock treatment 295930.0 22100.0 0.45 305069.0 27100.0 0.56 0.7163 0.9936 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F09 mock treatment 281963.0 8170.0 0.17 291534.0 13500.0 0.28 0.3167 0.9678 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F10 mock treatment 294429.0 20600.0 0.42 297453.0 19500.0 0.41 0.5826 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F11 mock treatment 305455.0 31700.0 0.64 313931.0 35900.0 0.75 0.9834 0.9971 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F12 mock treatment 300500.0 26700.0 0.54 303148.0 25200.0 0.52 0.7535 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F13 mock treatment 312322.0 38500.0 0.78 295898.0 17900.0 0.37 0.8162 0.9428 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F14 mock treatment 288269.0 14500.0 0.29 287165.0 9180.0 0.19 0.3428 0.9784 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F15 mock treatment 302722.0 28900.0 0.59 316763.0 38800.0 0.81 0.986 0.9876 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F16 mock treatment 292550.0 18800.0 0.38 277072.0 -915.0 -0.02 0.2554 0.6708 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F17 mock treatment 285940.0 12200.0 0.25 280759.0 2770.0 0.06 0.215 0.8498 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F18 mock treatment 278947.0 5160.0 0.1 286115.0 8130.0 0.17 0.1937 0.9731 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F19 mock treatment 275992.0 2200.0 0.04 278079.0 92.0 0.0 0.0329 0.7368 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F20 mock treatment 268610.0 -5180.0 -0.11 289597.0 11600.0 0.24 0.0968 0.367 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F21 mock treatment 274976.0 1190.0 0.02 273735.0 -4250.0 -0.09 -0.0456 -0.4972 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F22 mock treatment 242568.0 -31200.0 -0.63 260248.0 -17700.0 -0.37 -0.7089 -0.9672 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F23 mock treatment 252814.0 -21000.0 -0.43 246322.0 -31700.0 -0.66 -0.7672 -0.9774 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base F24 mock treatment 239176.0 -34600.0 -0.7 282240.0 4250.0 0.09 -0.4335 -0.613 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G01 mock treatment 253152.0 -20600.0 -0.42 262593.0 -15400.0 -0.32 -0.5226 -0.9914 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G02 mock treatment 253215.0 -20600.0 -0.42 239760.0 -38200.0 -0.8 -0.8581 -0.9545 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G03 mock treatment 276437.0 2650.0 0.05 288457.0 10500.0 0.22 0.1922 0.8556 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G04 mock treatment 302085.0 28300.0 0.57 281771.0 3780.0 0.08 0.4614 0.7968 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G05 mock treatment 290783.0 17000.0 0.34 272707.0 -5280.0 -0.11 0.1658 0.4585 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G06 mock treatment 284490.0 10700.0 0.22 280974.0 2990.0 0.06 0.1974 0.8747 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G07 mock treatment 283276.0 9490.0 0.19 260819.0 -17200.0 -0.36 -0.1169 -0.2879 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G08 mock treatment 276363.0 2570.0 0.05 281603.0 3620.0 0.08 0.0902 0.9839 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G09 mock treatment 276950.0 3160.0 0.06 280933.0 2950.0 0.06 0.0887 0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G10 mock treatment 295039.0 21200.0 0.43 309483.0 31500.0 0.66 0.7686 0.9792 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G11 mock treatment 293370.0 19600.0 0.4 282501.0 4510.0 0.09 0.3472 0.8511 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G12 mock treatment 299367.0 25600.0 0.52 285947.0 7960.0 0.17 0.4839 0.8889 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G13 mock treatment 286795.0 13000.0 0.26 291632.0 13600.0 0.28 0.3874 0.9993 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G14 mock treatment 317451.0 43700.0 0.89 289215.0 11200.0 0.23 0.7913 0.8643 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G15 mock treatment 266659.0 -7130.0 -0.14 302183.0 24200.0 0.5 0.2542 0.4848 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G16 mock treatment 298739.0 24900.0 0.51 285842.0 7850.0 0.16 0.4734 0.8904 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G17 mock treatment 284215.0 10400.0 0.21 294295.0 16300.0 0.34 0.3897 0.9739 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G18 mock treatment 340883.0 67100.0 1.36 331548.0 53600.0 1.12 1.7508 0.9952 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G19 mock treatment 290697.0 16900.0 0.34 308012.0 30000.0 0.63 0.6847 0.9599 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G20 mock treatment 281115.0 7330.0 0.15 274915.0 -3070.0 -0.06 0.0598 0.3695 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G21 mock treatment 281011.0 7220.0 0.15 283627.0 5640.0 0.12 0.1866 0.9941 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G22 mock treatment 292298.0 18500.0 0.38 278873.0 886.0 0.02 0.2784 0.741 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G23 mock treatment 284596.0 10800.0 0.22 283047.0 5060.0 0.11 0.2294 0.9438 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base G24 mock treatment 254032.0 -19800.0 -0.4 272987.0 -5000.0 -0.1 -0.3569 -0.8623 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H01 mock treatment 273057.0 -733.0 -0.01 278523.0 536.0 0.01 -0.0026 -0.1405 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H02 mock treatment 266540.0 -7250.0 -0.15 264247.0 -13700.0 -0.29 -0.3063 -0.952 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H03 mock treatment 282747.0 8960.0 0.18 310054.0 32100.0 0.67 0.6008 0.8678 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H04 mock treatment 291667.0 17900.0 0.36 309005.0 31000.0 0.65 0.7132 0.9626 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H05 mock treatment 269224.0 -4570.0 -0.09 305564.0 27600.0 0.57 0.3408 0.5856 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H06 mock treatment 294297.0 20500.0 0.42 302878.0 24900.0 0.52 0.6606 0.994 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H07 mock treatment 40149.0 -234000.0 -4.74 79116.0 -199000.0 -4.14 -6.2789 -0.9978 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H08 mock treatment 291359.0 17600.0 0.36 257003.0 -21000.0 -0.44 -0.0573 -0.1016 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H09 mock treatment 321669.0 47900.0 0.97 277418.0 -569.0 -0.01 0.678 0.6984 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H10 mock treatment 267093.0 -6700.0 -0.14 297541.0 19600.0 0.41 0.1921 0.4473 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H11 mock treatment 302147.0 28400.0 0.57 295639.0 17700.0 0.37 0.6665 0.9767 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H12 mock treatment 266029.0 -7760.0 -0.16 285393.0 7410.0 0.15 -0.0022 -0.0098 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H13 mock treatment 264037.0 -9750.0 -0.2 305859.0 27900.0 0.58 0.2708 0.4414 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H14 mock treatment 250630.0 -23200.0 -0.47 301596.0 23600.0 0.49 0.0158 0.0232 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H15 mock treatment 272052.0 -1740.0 -0.04 297168.0 19200.0 0.4 0.2576 0.6423 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H16 mock treatment 274203.0 413.0 0.01 253083.0 -24900.0 -0.52 -0.3609 -0.6956 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H17 mock treatment 280691.0 6900.0 0.14 304217.0 26200.0 0.55 0.4853 0.8604 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H18 mock treatment 270727.0 -3060.0 -0.06 261971.0 -16000.0 -0.33 -0.2798 -0.8245 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H19 mock treatment 267764.0 -6030.0 -0.12 295679.0 17700.0 0.37 0.1742 0.4487 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H20 mock treatment 255101.0 -18700.0 -0.38 275217.0 -2770.0 -0.06 -0.3087 -0.8055 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H21 mock treatment 277256.0 3470.0 0.07 298029.0 20000.0 0.42 0.3449 0.8147 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H22 mock treatment 268316.0 -5470.0 -0.11 268360.0 -9630.0 -0.2 -0.2203 -0.9611 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H23 mock treatment 272154.0 -1640.0 -0.03 266418.0 -11600.0 -0.24 -0.1939 -0.7969 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base H24 mock treatment 232134.0 -41700.0 -0.84 247126.0 -30900.0 -0.64 -1.0518 -0.9909 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I01 mock treatment 255100.0 -18700.0 -0.38 270897.0 -7090.0 -0.15 -0.3724 -0.9156 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I02 mock treatment 286624.0 12800.0 0.26 276912.0 -1080.0 -0.02 0.1681 0.6439 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I03 mock treatment 271334.0 -2460.0 -0.05 264112.0 -13900.0 -0.29 -0.2396 -0.8169 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I04 mock treatment 315785.0 42000.0 0.85 271130.0 -6860.0 -0.14 0.501 0.5803 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I05 mock treatment 296366.0 22600.0 0.46 310007.0 32000.0 0.67 0.7953 0.9831 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I06 mock treatment 347858.0 74100.0 1.5 316400.0 38400.0 0.8 1.6276 0.9566 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I07 mock treatment 294546.0 20800.0 0.42 271271.0 -6720.0 -0.14 0.1986 0.4479 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I08 mock treatment 298688.0 24900.0 0.5 288129.0 10100.0 0.21 0.5063 0.9253 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I09 mock treatment 256677.0 -17100.0 -0.35 272366.0 -5620.0 -0.12 -0.3281 -0.8961 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I10 mock treatment 259944.0 -13800.0 -0.28 302692.0 24700.0 0.51 0.1654 0.2822 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I11 mock treatment 263478.0 -10300.0 -0.21 292528.0 14500.0 0.3 0.0664 0.1804 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I12 mock treatment 166497.0 -107000.0 -2.18 176814.0 -101000.0 -2.11 -3.0284 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I13 mock treatment 295138.0 21300.0 0.43 289732.0 11700.0 0.24 0.479 0.9635 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I14 mock treatment 284333.0 10500.0 0.21 292760.0 14800.0 0.31 0.3688 0.9841 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I15 mock treatment 280223.0 6430.0 0.13 253410.0 -24600.0 -0.51 -0.2698 -0.5107 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I16 mock treatment 250069.0 -23700.0 -0.48 288783.0 10800.0 0.22 -0.181 -0.3409 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I17 mock treatment 281058.0 7270.0 0.15 308579.0 30600.0 0.64 0.5548 0.8482 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I18 mock treatment 271294.0 -2500.0 -0.05 281505.0 3520.0 0.07 0.016 0.1802 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I19 mock treatment 311667.0 37900.0 0.77 343531.0 65500.0 1.37 1.5085 0.9629 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I20 mock treatment 257510.0 -16300.0 -0.33 277531.0 -456.0 -0.01 -0.2401 -0.7272 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I21 mock treatment 267912.0 -5880.0 -0.12 298622.0 20600.0 0.43 0.2197 0.4925 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I22 mock treatment 316350.0 42600.0 0.86 294319.0 16300.0 0.34 0.8507 0.9172 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I23 mock treatment 279587.0 5800.0 0.12 283516.0 5530.0 0.12 0.1645 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base I24 mock treatment 279203.0 5410.0 0.11 270014.0 -7970.0 -0.17 -0.0399 -0.2002 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J01 mock treatment 256550.0 -17200.0 -0.35 270875.0 -7110.0 -0.15 -0.3519 -0.927 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J02 mock treatment 256167.0 -17600.0 -0.36 289995.0 12000.0 0.25 -0.0757 -0.1736 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J03 mock treatment 279454.0 5660.0 0.11 303988.0 26000.0 0.54 0.4642 0.8384 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J04 mock treatment 280653.0 6860.0 0.14 326817.0 48800.0 1.02 0.8177 0.7964 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J05 mock treatment 303508.0 29700.0 0.6 304772.0 26800.0 0.56 0.8206 0.9993 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J06 mock treatment 296741.0 23000.0 0.47 316540.0 38600.0 0.8 0.8969 0.9663 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J07 mock treatment 275821.0 2030.0 0.04 334586.0 56600.0 1.18 0.8629 0.7314 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J08 mock treatment 314340.0 40600.0 0.82 346698.0 68700.0 1.43 1.5935 0.9653 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J09 mock treatment 325485.0 51700.0 1.05 318586.0 40600.0 0.85 1.3391 0.9943 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J10 mock treatment 280395.0 6610.0 0.13 307209.0 29200.0 0.61 0.5252 0.8425 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J11 mock treatment 284692.0 10900.0 0.22 280733.0 2750.0 0.06 0.1967 0.8617 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J12 mock treatment 297828.0 24000.0 0.49 327781.0 49800.0 1.04 1.0781 0.9407 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J13 mock treatment 292748.0 19000.0 0.38 294886.0 16900.0 0.35 0.5207 0.999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J14 mock treatment 279568.0 5780.0 0.12 315027.0 37000.0 0.77 0.6285 0.8052 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J15 mock treatment 256204.0 -17600.0 -0.36 292034.0 14000.0 0.29 -0.0452 -0.0979 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J16 mock treatment 284171.0 10400.0 0.21 294374.0 16400.0 0.34 0.3902 0.973 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J17 mock treatment 287212.0 13400.0 0.27 304969.0 27000.0 0.56 0.5899 0.9446 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J18 mock treatment 249761.0 -24000.0 -0.49 275530.0 -2460.0 -0.05 -0.3807 -0.7771 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J19 mock treatment 258308.0 -15500.0 -0.31 312201.0 34200.0 0.71 0.2821 0.3622 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J20 mock treatment 268907.0 -4880.0 -0.1 271363.0 -6620.0 -0.14 -0.1676 -0.9867 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J21 mock treatment 263902.0 -9890.0 -0.2 267948.0 -10000.0 -0.21 -0.2896 -0.9998 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J22 mock treatment 254954.0 -18800.0 -0.38 280360.0 2370.0 0.05 -0.2351 -0.6105 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J23 mock treatment 269911.0 -3880.0 -0.08 310180.0 32200.0 0.67 0.4186 0.62 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base J24 mock treatment 269215.0 -4570.0 -0.09 267273.0 -10700.0 -0.22 -0.2234 -0.9243 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K01 mock treatment 268007.0 -5780.0 -0.12 253489.0 -24500.0 -0.51 -0.4438 -0.8475 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K02 mock treatment 257816.0 -16000.0 -0.32 289084.0 11100.0 0.23 -0.0655 -0.1647 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K03 mock treatment 314195.0 40400.0 0.82 295543.0 17600.0 0.37 0.8378 0.934 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K04 mock treatment 307802.0 34000.0 0.69 275206.0 -2780.0 -0.06 0.4466 0.6454 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K05 mock treatment 288267.0 14500.0 0.29 277622.0 -365.0 -0.01 0.2022 0.6886 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K06 mock treatment 280717.0 6930.0 0.14 277173.0 -814.0 -0.02 0.0873 0.6172 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K07 mock treatment 287261.0 13500.0 0.27 265197.0 -12800.0 -0.27 0.0047 0.0123 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K08 mock treatment 284499.0 10700.0 0.22 306384.0 28400.0 0.59 0.5718 0.9074 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K09 mock treatment 303334.0 29500.0 0.6 270637.0 -7350.0 -0.15 0.3152 0.5099 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K10 mock treatment 282131.0 8340.0 0.17 288817.0 10800.0 0.23 0.2791 0.9899 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K11 mock treatment 293038.0 19200.0 0.39 312400.0 34400.0 0.72 0.7829 0.9591 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K12 mock treatment 273618.0 -172.0 0.0 305908.0 27900.0 0.58 0.4088 0.7029 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K13 mock treatment 302896.0 29100.0 0.59 313582.0 35600.0 0.74 0.9416 0.9936 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K14 mock treatment 293224.0 19400.0 0.39 291793.0 13800.0 0.29 0.482 0.988 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K15 mock treatment 277168.0 3380.0 0.07 305503.0 27500.0 0.57 0.4538 0.786 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K16 mock treatment 290123.0 16300.0 0.33 314046.0 36100.0 0.75 0.7653 0.9322 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K17 mock treatment 264985.0 -8800.0 -0.18 294464.0 16500.0 0.34 0.1165 0.3011 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K18 mock treatment 250230.0 -23600.0 -0.48 294520.0 16500.0 0.34 -0.0942 -0.1599 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K19 mock treatment 266893.0 -6900.0 -0.14 269300.0 -8690.0 -0.18 -0.2268 -0.9919 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K20 mock treatment 263071.0 -10700.0 -0.22 306946.0 29000.0 0.6 0.2729 0.4256 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K21 mock treatment 282198.0 8410.0 0.17 285365.0 7380.0 0.15 0.2292 0.9987 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K22 mock treatment 261047.0 -12700.0 -0.26 283007.0 5020.0 0.1 -0.1087 -0.3901 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K23 mock treatment 293991.0 20200.0 0.41 258235.0 -19800.0 -0.41 -0.0014 -0.0024 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base K24 mock treatment 262802.0 -11000.0 -0.22 285043.0 7060.0 0.15 -0.0536 -0.2007 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L01 mock treatment 216041.0 -57700.0 -1.17 250048.0 -27900.0 -0.58 -1.2394 -0.948 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L02 mock treatment 272056.0 -1730.0 -0.04 277888.0 -99.0 0.0 -0.0263 -0.7473 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L03 mock treatment 280999.0 7210.0 0.15 283495.0 5510.0 0.11 0.1845 0.9928 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L04 mock treatment 287835.0 14000.0 0.28 320582.0 42600.0 0.89 0.8288 0.8893 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L05 mock treatment 268405.0 -5380.0 -0.11 319499.0 41500.0 0.86 0.5343 0.613 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L06 mock treatment 51506.0 -222000.0 -4.51 100027.0 -178000.0 -3.71 -5.808 -0.9953 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L07 mock treatment 268413.0 -5380.0 -0.11 307077.0 29100.0 0.61 0.3514 0.5708 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L08 mock treatment 262518.0 -11300.0 -0.23 338540.0 60600.0 1.26 0.7304 0.5697 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L09 mock treatment 294267.0 20500.0 0.42 322539.0 44600.0 0.93 0.9498 0.9342 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L10 mock treatment 277367.0 3580.0 0.07 313600.0 35600.0 0.74 0.5759 0.7725 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L11 mock treatment 269869.0 -3920.0 -0.08 293567.0 15600.0 0.32 0.1733 0.5186 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L12 mock treatment 293515.0 19700.0 0.4 299640.0 21700.0 0.45 0.6017 0.9982 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L13 mock treatment 106786.0 -167000.0 -3.39 144851.0 -133000.0 -2.77 -4.3553 -0.9951 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L14 mock treatment 252568.0 -21200.0 -0.43 323854.0 45900.0 0.96 0.3715 0.3545 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L15 mock treatment 295906.0 22100.0 0.45 310517.0 32500.0 0.68 0.7962 0.9799 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L16 mock treatment 308827.0 35000.0 0.71 285565.0 7580.0 0.16 0.6139 0.8437 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L17 mock treatment 274759.0 969.0 0.02 313283.0 35300.0 0.74 0.5338 0.7257 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L18 mock treatment 257472.0 -16300.0 -0.33 299577.0 21600.0 0.45 0.0841 0.1507 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L19 mock treatment 270759.0 -3030.0 -0.06 293408.0 15400.0 0.32 0.1837 0.5617 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L20 mock treatment 292523.0 18700.0 0.38 305561.0 27600.0 0.57 0.6747 0.9798 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L21 mock treatment 338123.0 64300.0 1.3 309851.0 31900.0 0.66 1.3916 0.9509 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L22 mock treatment 254434.0 -19400.0 -0.39 261202.0 -16800.0 -0.35 -0.5247 -0.9983 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L23 mock treatment 241793.0 -32000.0 -0.65 254223.0 -23800.0 -0.5 -0.8087 -0.9911 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base L24 mock treatment 248639.0 -25200.0 -0.51 272848.0 -5140.0 -0.11 -0.4362 -0.8373 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M01 mock treatment 229685.0 -44100.0 -0.89 253792.0 -24200.0 -0.5 -0.9887 -0.9632 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M02 mock treatment 266504.0 -7290.0 -0.15 322195.0 44200.0 0.92 0.5468 0.5862 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M03 mock treatment 289828.0 16000.0 0.33 275013.0 -2970.0 -0.06 0.1861 0.5622 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M04 mock treatment 278390.0 4600.0 0.09 276153.0 -1830.0 -0.04 0.0389 0.3862 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M05 mock treatment 308560.0 34800.0 0.7 317957.0 40000.0 0.83 1.0872 0.9966 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M06 mock treatment 282093.0 8300.0 0.17 328645.0 50700.0 1.06 0.8653 0.8097 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M07 mock treatment 304727.0 30900.0 0.63 298654.0 20700.0 0.43 0.7479 0.9832 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M08 mock treatment 293731.0 19900.0 0.4 313392.0 35400.0 0.74 0.8074 0.9599 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M09 mock treatment 324800.0 51000.0 1.03 272645.0 -5340.0 -0.11 0.6525 0.6274 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M10 mock treatment 327131.0 53300.0 1.08 304050.0 26100.0 0.54 1.1486 0.9492 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M11 mock treatment 283959.0 10200.0 0.21 278749.0 762.0 0.02 0.157 0.7593 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M12 mock treatment 299293.0 25500.0 0.52 264697.0 -13300.0 -0.28 0.1698 0.2895 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M13 mock treatment 323509.0 49700.0 1.01 260916.0 -17100.0 -0.36 0.4613 0.4315 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M14 mock treatment 262860.0 -10900.0 -0.22 265763.0 -12200.0 -0.25 -0.3368 -0.9976 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M15 mock treatment 284020.0 10200.0 0.21 285783.0 7800.0 0.16 0.2615 0.9927 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M16 mock treatment 260319.0 -13500.0 -0.27 263921.0 -14100.0 -0.29 -0.4003 -0.9994 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M17 mock treatment 275030.0 1240.0 0.03 267543.0 -10400.0 -0.22 -0.1361 -0.6213 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M18 mock treatment 302360.0 28600.0 0.58 269612.0 -8380.0 -0.17 0.2862 0.4731 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M19 mock treatment 273008.0 -782.0 -0.02 258494.0 -19500.0 -0.41 -0.2984 -0.7341 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M20 mock treatment 276038.0 2250.0 0.05 274746.0 -3240.0 -0.07 -0.0155 -0.1905 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M21 mock treatment 299405.0 25600.0 0.52 281298.0 3310.0 0.07 0.416 0.7941 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M22 mock treatment 298570.0 24800.0 0.5 271921.0 -6070.0 -0.13 0.2659 0.5132 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M23 mock treatment 284166.0 10400.0 0.21 266417.0 -11600.0 -0.24 -0.0217 -0.0678 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base M24 mock treatment 282537.0 8750.0 0.18 260811.0 -17200.0 -0.36 -0.1276 -0.3196 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N01 mock treatment 280665.0 6880.0 0.14 274665.0 -3320.0 -0.07 0.0496 0.3189 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N02 mock treatment 299544.0 25800.0 0.52 372502.0 94500.0 1.97 1.7615 0.8647 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N03 mock treatment 305471.0 31700.0 0.64 293314.0 15300.0 0.32 0.6799 0.948 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N04 mock treatment 360274.0 86500.0 1.75 292534.0 14500.0 0.3 1.4541 0.8172 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N05 mock treatment 320993.0 47200.0 0.96 314908.0 36900.0 0.77 1.2205 0.9941 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N06 mock treatment 298036.0 24200.0 0.49 291521.0 13500.0 0.28 0.5469 0.9652 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N07 mock treatment 292834.0 19000.0 0.39 295584.0 17600.0 0.37 0.5322 0.9997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N08 mock treatment 314112.0 40300.0 0.82 299027.0 21000.0 0.44 0.888 0.9573 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N09 mock treatment 326920.0 53100.0 1.08 299027.0 21000.0 0.44 1.0716 0.9215 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N10 mock treatment 265874.0 -7920.0 -0.16 297631.0 19600.0 0.41 0.1759 0.4002 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N11 mock treatment 234424.0 -39400.0 -0.8 312262.0 34300.0 0.71 -0.0594 -0.0555 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N12 mock treatment 291985.0 18200.0 0.37 277694.0 -293.0 -0.01 0.2565 0.6953 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N13 mock treatment 323204.0 49400.0 1.0 288801.0 10800.0 0.23 0.8677 0.845 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N14 mock treatment 281296.0 7510.0 0.15 276295.0 -1690.0 -0.04 0.0827 0.5293 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N15 mock treatment 259012.0 -14800.0 -0.3 294411.0 16400.0 0.34 0.0301 0.0662 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N16 mock treatment 269035.0 -4750.0 -0.1 330480.0 52500.0 1.09 0.7051 0.6423 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N17 mock treatment 268043.0 -5750.0 -0.12 282070.0 4080.0 0.09 -0.0222 -0.1541 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N18 mock treatment 283186.0 9400.0 0.19 264828.0 -13200.0 -0.27 -0.0592 -0.1772 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N19 mock treatment 261489.0 -12300.0 -0.25 288656.0 10700.0 0.22 -0.0192 -0.0574 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N20 mock treatment 252800.0 -21000.0 -0.43 281026.0 3040.0 0.06 -0.2561 -0.5953 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N21 mock treatment 445966.0 172000.0 3.49 263003.0 -15000.0 -0.31 2.2474 0.6413 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N22 mock treatment 266605.0 -7180.0 -0.15 269872.0 -8120.0 -0.17 -0.2225 -0.9972 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N23 mock treatment 229053.0 -44700.0 -0.91 279550.0 1560.0 0.03 -0.6183 -0.6813 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base N24 mock treatment 259346.0 -14400.0 -0.29 246927.0 -31100.0 -0.65 -0.6646 -0.9357 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O01 mock treatment 246155.0 -27600.0 -0.56 252347.0 -25600.0 -0.53 -0.7739 -0.9997 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O02 mock treatment 267160.0 -6630.0 -0.13 262282.0 -15700.0 -0.33 -0.3264 -0.9228 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O03 mock treatment 257036.0 -16800.0 -0.34 278678.0 691.0 0.01 -0.23 -0.6765 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O04 mock treatment 278115.0 4330.0 0.09 292396.0 14400.0 0.3 0.2743 0.877 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O05 mock treatment 293992.0 20200.0 0.41 282418.0 4430.0 0.09 0.3549 0.8453 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O06 mock treatment 270751.0 -3040.0 -0.06 281796.0 3810.0 0.08 0.0125 0.1249 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O07 mock treatment 285386.0 11600.0 0.24 244538.0 -33400.0 -0.7 -0.3265 -0.444 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O08 mock treatment 286425.0 12600.0 0.26 297503.0 19500.0 0.41 0.4686 0.9752 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O09 mock treatment 268856.0 -4930.0 -0.1 279052.0 1060.0 0.02 -0.055 -0.5372 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O10 mock treatment 267850.0 -5940.0 -0.12 293133.0 15100.0 0.32 0.138 0.4085 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O11 mock treatment 178208.0 -95600.0 -1.94 248686.0 -29300.0 -0.61 -1.8018 -0.8869 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O12 mock treatment 282121.0 8330.0 0.17 299331.0 21300.0 0.44 0.4338 0.9121 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O13 mock treatment 285237.0 11400.0 0.23 283197.0 5210.0 0.11 0.2408 0.9401 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O14 mock treatment 279030.0 5240.0 0.11 286420.0 8430.0 0.18 0.1993 0.971 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O15 mock treatment 259397.0 -14400.0 -0.29 286906.0 8920.0 0.19 -0.0749 -0.2166 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O16 mock treatment 269012.0 -4780.0 -0.1 279105.0 1120.0 0.02 -0.052 -0.5222 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O17 mock treatment 256236.0 -17600.0 -0.36 264851.0 -13100.0 -0.27 -0.4451 -0.9916 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O18 mock treatment 284389.0 10600.0 0.21 276055.0 -1930.0 -0.04 0.1235 0.5648 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O19 mock treatment 257452.0 -16300.0 -0.33 275556.0 -2430.0 -0.05 -0.27 -0.8059 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O20 mock treatment 303284.0 29500.0 0.6 263733.0 -14300.0 -0.3 0.2128 0.3188 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O21 mock treatment 249553.0 -24200.0 -0.49 237183.0 -40800.0 -0.85 -0.9485 -0.9661 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O22 mock treatment 290213.0 16400.0 0.33 302171.0 24200.0 0.5 0.5917 0.9798 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O23 mock treatment 304543.0 30800.0 0.62 270124.0 -7860.0 -0.16 0.325 0.5042 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base O24 mock treatment 293181.0 19400.0 0.39 297516.0 19500.0 0.41 0.5657 0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P01 mock treatment 235883.0 -37900.0 -0.77 279572.0 1580.0 0.03 -0.5201 -0.6761 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P02 mock treatment 250472.0 -23300.0 -0.47 265016.0 -13000.0 -0.27 -0.5253 -0.9648 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P03 mock treatment 276894.0 3100.0 0.06 282574.0 4590.0 0.1 0.1121 0.9795 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P04 mock treatment 301952.0 28200.0 0.57 276752.0 -1240.0 -0.03 0.3855 0.6746 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P05 mock treatment 284226.0 10400.0 0.21 283930.0 5940.0 0.12 0.2371 0.9674 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P06 mock treatment 288861.0 15100.0 0.31 270026.0 -7960.0 -0.17 0.0988 0.2841 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P07 mock treatment 249459.0 -24300.0 -0.49 261861.0 -16100.0 -0.34 -0.5863 -0.9825 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P08 mock treatment 270030.0 -3760.0 -0.08 275291.0 -2700.0 -0.06 -0.0936 -0.9887 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P09 mock treatment 258599.0 -15200.0 -0.31 279506.0 1520.0 0.03 -0.1954 -0.6311 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P10 mock treatment 294461.0 20700.0 0.42 253112.0 -24900.0 -0.52 -0.0701 -0.1052 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P11 mock treatment 272658.0 -1130.0 -0.02 275632.0 -2360.0 -0.05 -0.0509 -0.9401 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P12 mock treatment 278613.0 4820.0 0.1 279277.0 1290.0 0.03 0.0881 0.8692 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P13 mock treatment 267429.0 -6360.0 -0.13 263772.0 -14200.0 -0.3 -0.3006 -0.9306 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P14 mock treatment 271629.0 -2160.0 -0.04 243357.0 -34600.0 -0.72 -0.5411 -0.7487 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P15 mock treatment 253209.0 -20600.0 -0.42 258176.0 -19800.0 -0.41 -0.5869 -1.0 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P16 mock treatment 237464.0 -36300.0 -0.74 244749.0 -33200.0 -0.69 -1.0104 -0.9995 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P17 mock treatment 252752.0 -21000.0 -0.43 236060.0 -41900.0 -0.87 -0.9192 -0.9457 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P18 mock treatment 244455.0 -29300.0 -0.59 240848.0 -37100.0 -0.77 -0.9676 -0.9916 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P19 mock treatment 248960.0 -24800.0 -0.5 276337.0 -1650.0 -0.03 -0.3802 -0.7536 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P20 mock treatment 242276.0 -31500.0 -0.64 246642.0 -31300.0 -0.65 -0.9135 -0.9999 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P21 mock treatment 282168.0 8380.0 0.17 239957.0 -38000.0 -0.79 -0.4401 -0.5432 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P22 mock treatment 247395.0 -26400.0 -0.54 255713.0 -22300.0 -0.46 -0.7065 -0.9975 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P23 mock treatment 250991.0 -22800.0 -0.46 229672.0 -48300.0 -1.01 -1.0386 -0.9377 1063.0002 GusReporter(1063.0002) SigBInhibition 1063.0002.Base P24 mock treatment 251449.0 -22300.0 -0.45 247999.0 -30000.0 -0.62 -0.762 -0.9875