ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A01 mock treatment 912280.0 -169000.0 -0.83 824330.0 -258000.0 -1.53 835130.0 -198715.71428571 -1.13814274754082 -2.0199 -0.9706 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A02 mock treatment 930800.0 -151000.0 -0.74 905000.0 -177000.0 -1.05 860010.0 -173835.71428571 -0.995642736101856 -1.6084 -0.9891 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A03 compound treatment 854520.0 -227000.0 -1.11 996540.0 -85700.0 -0.51 882030.0 -151815.71428571 -0.869523352987468 -1.4365 -0.9586 2060025 SpecPlus_000001 CC(=O)O[C@H]1C[C@@]2(C)[C@@H](OC(=O)[C@H]3O[C@]32[C@]4(C)[C@@H](CC5C(C)(C)[C@@H](C[C@H](OC(=O)C)[C@]5(C)C14)OC(=O)C)OC(=O)C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A04 compound treatment 805130.0 -276000.0 -1.35 966830.0 -115000.0 -0.69 845150.0 -188695.71428571 -1.08075327348059 -1.7998 -0.9672 2060026 SpecPlus_000002 COC(=O)C[C@H]1C(C)(C)[C@@H](OC(=O)C)[C@@H]2CC3C(CC[C@@]4(C)[C@@H](OC(=O)CC34)c5ccoc5)[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A05 compound treatment 29480.0 -1050000.0 -5.14 33970.0 -1050000.0 -6.23 25690.0 -1008155.71428571 -5.77420421294095 -9.9002 -0.9969 3054122 SpecPlus_000003 CC(=O)O[C@@H]1C[C@@]2(C)[C@@H](C[C@H]3O[C@]32[C@@]4(C)C1[C@@]5(C)C=CC(=O)C(C)(C)C5=C(O)C4=O)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A06 compound treatment 979370.0 -102000.0 -0.5 1037710.0 -44500.0 -0.26 934180.0 -99665.71428571 -0.570834623222919 -0.7705 -0.9595 2060027 SpecPlus_000004 CC(=O)O[C@@H]1CC2C(C)(C)[C@@H](O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A07 compound treatment 906590.0 -175000.0 -0.85 1041340.0 -40900.0 -0.24 1028820.0 -5025.71428571001 -0.0287847404824213 -0.6504 -0.7316 2060028 SpecPlus_000005 COC(=O)C[C@H]1C2(C)CC3(OC4(C)O[C@@]56[C@H](OC(=O)C)[C@@]3(O)C2OC(=O)C(C)C)[C@]1(C)[C@@]6(O4)[C@H](OC(=O)C)C(OC(=O)C)[C@@]7(C)[C@@H](OC(=O)/C(=C(\O)/C(C)C)/C57)c8ccoc8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A08 compound treatment 826160.0 -255000.0 -1.25 1053090.0 -29100.0 -0.17 954910.0 -78935.71428571 -0.452103705331852 -1.0813 -0.8081 2060029 SpecPlus_000006 CC(=O)O[C@H]1CC[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A09 compound treatment 351650.0 -730000.0 -3.57 270140.0 -812000.0 -4.83 309520.0 -724325.71428571 -4.14857003903736 -7.2421 -0.9925 2060030 SpecPlus_000007 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2CC3C(CC[C@@]4(C)[C@@H](OC(=O)C=C34)c5ccoc5)[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A10 compound treatment 520600.0 -561000.0 -2.74 531540.0 -551000.0 -3.27 515140.0 -518705.71428571 -2.97088304739428 -5.1881 -0.9973 3173352 SpecPlus_000008 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A11 compound treatment 27250.0 -1050000.0 -5.15 28740.0 -1050000.0 -6.26 22330.0 -1011515.71428571 -5.79344858747611 -9.9356 -0.9968 2060031 SpecPlus_000009 C[C@]12CCC3[C@@]4(C)C=CC(=O)C(C)(C)C4=C(O)C(=O)[C@@]3(C)[C@]25O[C@@H]5C[C@H]1c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A12 compound treatment 876080.0 -205000.0 -1.0 986840.0 -95400.0 -0.57 841570.0 -192275.71428571 -1.10125769634842 -1.5428 -0.9677 2060032 SpecPlus_000010 C[C@]12CCC3[C@@](C)([C@H](O)CC4[C@]3(C)[C@@H](O)CC(=O)OC4(C)C)C25OC5C(=O)OC1c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A13 compound treatment 614370.0 -467000.0 -2.28 666080.0 -416000.0 -2.47 636160.0 -397685.71428571 -2.27774191458305 -4.0615 -0.9992 2060033 SpecPlus_000011 CO[C@@H]1C(OC(=O)C(C)C)[C@@]2(C)[C@@H](OC(=O)/C(=C(\O)/C(C)C)/C2[C@@]34OC5(C)O[C@]14[C@]6(C)[C@@H](CC(=O)OC)C7(C)CC6(O5)[C@](OC)(C7OC(=O)C)[C@H]3OC)c8ccoc8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A14 compound treatment 458890.0 -623000.0 -3.04 575360.0 -507000.0 -3.01 582770.0 -451075.71428571 -2.58353273494986 -4.9881 -0.9974 2060034 SpecPlus_000012 CC(C)c1c(O)ccc2c1CCC3[C@](C)(CCC[C@@]32C)C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A15 compound treatment 727910.0 -354000.0 -1.73 833950.0 -248000.0 -1.48 712350.0 -321495.71428571 -1.84136426701333 -2.9129 -0.9959 2060035 SpecPlus_000013 CC1(C)C2C[C@@H](O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)[C@@]2(C)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A16 compound treatment 836590.0 -245000.0 -1.2 889090.0 -193000.0 -1.15 848290.0 -185555.71428571 -1.06276894727809 -1.9675 -0.9988 2060036 SpecPlus_000014 CC1=CCc2c(O)c3c(=O)cc(C)oc3cc2OC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A17 compound treatment 903600.0 -178000.0 -0.87 878000.0 -204000.0 -1.21 755400.0 -278445.71428571 -1.59479571828152 -2.1237 -0.972 2060037 SpecPlus_000015 CC(=O)O[C@@H]1CC[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A18 compound treatment 310410.0 -771000.0 -3.77 324760.0 -757000.0 -4.5 269940.0 -763905.71428571 -4.37526418906768 -7.3017 -0.9971 3054128 SpecPlus_000016 COC1C[C@H]2N3CC(O)C2(C=C1)c4cc5OCOc5cc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A19 compound treatment 853800.0 -228000.0 -1.11 977350.0 -105000.0 -0.62 897720.0 -136125.71428571 -0.77965899689915 -1.4525 -0.9717 2060038 SpecPlus_000017 COC(=O)C[C@H]1C(C)(C)C(=O)C=C[C@]1(C)C2CC[C@@]3(C)[C@@H](OC(=O)C=C3C2=C)c4ccoc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A20 compound treatment 733800.0 -348000.0 -1.7 907870.0 -174000.0 -1.04 756870.0 -276975.71428571 -1.58637630442239 -2.4953 -0.9804 2060039 SpecPlus_000018 CC(=CCc1c(O)cc2oc(C)cc(=O)c2c1O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A21 compound treatment 876930.0 -205000.0 -1.0 1012240.0 -70000.0 -0.42 907840.0 -126005.71428571 -0.721696773596806 -1.234 -0.9484 3173357 SpecPlus_000019 CC(=C)[C@@H]1CC[C@@]2(CCC3[C@H](CCC4[C@@]3(C)CCC5C(C)(C)[C@H](O)CC[C@@]54C)C12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A22 compound treatment 886790.0 -195000.0 -0.95 1032710.0 -49500.0 -0.29 846620.0 -187225.71428571 -1.07233385962146 -1.3384 -0.9145 3054129 SpecPlus_000020 CO[C@@H]1CC2N3CC(O)C2(C=C1)c4cc5OCOc5c(OC)c4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A23 mock treatment 890560.0 -191000.0 -0.93 982170.0 -100000.0 -0.6 946930.0 -86915.71428571 -0.497809094852871 -1.1695 -0.9639 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 A24 mock treatment 851650.0 -230000.0 -1.12 930180.0 -152000.0 -0.9 885890.0 -147955.71428571 -0.847415232241712 -1.6596 -0.9924 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B01 mock treatment 1119380.0 37900.0 0.19 949290.0 -133000.0 -0.79 985300.0 -48545.71428571 -0.278045210652185 -0.5101 -0.5943 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B02 mock treatment 992640.0 -88900.0 -0.43 1031130.0 -51100.0 -0.3 960190.0 -73655.71428571 -0.421862545348021 -0.6696 -0.9887 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B03 compound treatment 884960.0 -197000.0 -0.96 970110.0 -112000.0 -0.67 903040.0 -130805.71428571 -0.749188737218471 -1.3719 -0.988 2060040 SpecPlus_000021 CCOC(=O)C1(O)Oc2cc(OC)cc(OC)c2C(=O)C1c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B04 compound treatment 973090.0 -108000.0 -0.53 1017400.0 -64800.0 -0.39 989470.0 -44375.71428571 -0.254161567255863 -0.6751 -0.9608 3054130 SpecPlus_000022 CC(CCC=C(C)C)[C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)C4(C)CC[C@H](OC(=O)C)C(C)(C)C4CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B05 compound treatment 871750.0 -210000.0 -1.02 1024860.0 -57400.0 -0.34 955040.0 -78805.71428571 -0.451359131317099 -1.0492 -0.8963 2060041 SpecPlus_000023 COc1cc2CCN(C)C(Cc3ccc(O)cc3)c2cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B06 compound treatment 664860.0 -417000.0 -2.04 672360.0 -410000.0 -2.44 664230.0 -369615.71428571 -2.11697120232052 -3.8047 -0.9969 2060042 SpecPlus_000024 CCC(C)c1cnc(CC(C)C)c(=O)n1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B07 compound treatment 1028670.0 -52800.0 -0.26 1071150.0 -11100.0 -0.07 948600.0 -85245.71428571 -0.4882441825095 -0.4689 -0.8432 2060043 SpecPlus_000025 COc1cc(OC)c(Cl)c2OC3(C(C)CC(=O)C=C3O)C(=O)c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B08 compound treatment 625140.0 -456000.0 -2.23 593030.0 -489000.0 -2.91 565120.0 -468725.71428571 -2.6846229761837 -4.5168 -0.9942 2060044 SpecPlus_000026 CC(=O)Oc1cc(cc(OC(=O)C)c1OC(=O)C)c2coc3cc(OC(=O)C)c(OC(=O)C)c(OC(=O)C)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B09 compound treatment 27210.0 -1050000.0 -5.15 30830.0 -1050000.0 -6.25 25760.0 -1008085.71428571 -5.77380328847147 -9.9172 -0.9969 2060045 SpecPlus_000027 CC(=C)/C=C\1/C=CC(=O)C(=C1)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B10 compound treatment 893560.0 -188000.0 -0.92 936840.0 -145000.0 -0.86 823900.0 -209945.71428571 -1.20246248743067 -1.7235 -0.9891 2060046 SpecPlus_000028 C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)[C@@]4(C)O[C@]43[C@H]2OC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B11 compound treatment 928700.0 -153000.0 -0.75 1038400.0 -43800.0 -0.26 886530.0 -147315.71428571 -0.843749637092157 -1.0686 -0.9241 2060047 SpecPlus_000029 OC(C(=O)O)C(O)(Cc1ccc(O)cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B12 compound treatment 996170.0 -85300.0 -0.42 1125600.0 43400.0 0.26 1004400.0 -29445.71428571 -0.168650105407643 -0.1892 -0.3649 2060048 SpecPlus_000030 CC(=O)c1c(O)c(C)c(O)c2c1oc3c(C(=O)C)c(O)c(C)c(O)c32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B13 compound treatment 991230.0 -90300.0 -0.44 1026340.0 -55900.0 -0.33 1005540.0 -28305.71428571 -0.162120764047497 -0.5401 -0.9384 2060049 SpecPlus_000031 Cc1cc(=O)c2c(O)c(C)c(O)cc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B14 compound treatment 750720.0 -331000.0 -1.62 840980.0 -241000.0 -1.43 752990.0 -280855.71428571 -1.60859897501656 -2.6901 -0.9985 2060050 SpecPlus_000032 COc1ccc(cc1)c2cc(=O)c3c(OC)cccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B15 compound treatment 926970.0 -155000.0 -0.75 1028590.0 -53600.0 -0.32 803720.0 -230125.71428571 -1.31804328449009 -1.381 -0.8898 2060051 SpecPlus_000033 Cc1cc(=O)c2c(O)cc(O)c(C)c2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B16 compound treatment 804640.0 -277000.0 -1.35 880930.0 -201000.0 -1.2 762210.0 -271635.71428571 -1.55579149489328 -2.3703 -0.9943 2069262 SpecPlus_000034 COc1cc(/C=C/C=O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B17 compound treatment 594840.0 -487000.0 -2.38 630900.0 -451000.0 -2.68 558240.0 -475605.71428571 -2.72402812404142 -4.495 -0.9982 2060052 SpecPlus_000035 Oc1ccc2C3=C4C=CC(=O)C=C4C[C@@]3(O)COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B18 compound treatment 809760.0 -272000.0 -1.33 816840.0 -265000.0 -1.58 788960.0 -244885.71428571 -1.40258107262671 -2.4875 -0.9973 2060053 SpecPlus_000036 COc1c(CC=C(C)C)c2OC(C)(C)C=Cc2c3oc(=O)c(c(OC(=O)C)c13)c4ccc(OC(=O)C)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B19 compound treatment 652000.0 -429000.0 -2.1 707770.0 -374000.0 -2.23 667270.0 -366575.71428571 -2.09955962536013 -3.7093 -0.9996 2060054 SpecPlus_000037 CC(=O)OC(OC(=O)C)c1c(OC(=O)C)cc(C)c2C(=O)Oc3c(C)c(OC(=O)C)c4C(=O)OC(OC(=O)C)c4c3Oc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B20 compound treatment 986670.0 -94800.0 -0.46 1068920.0 -13300.0 -0.08 987320.0 -46525.71428571 -0.266475675961401 -0.467 -0.8644 3173360 SpecPlus_000038 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4CCCC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B21 compound treatment 795330.0 -286000.0 -1.4 835120.0 -247000.0 -1.47 813280.0 -220565.71428571 -1.26328845694361 -2.385 -0.9981 2120750 SpecPlus_000039 CC(C)C(C)/C=C/C(C)C1CCC2C3=CC=C4CC(O)CCC4(C)C3CCC12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B22 compound treatment 990170.0 -91300.0 -0.45 1058250.0 -24000.0 -0.14 846260.0 -187585.71428571 -1.07439575689308 -0.9602 -0.8193 3173475 SpecPlus_000040 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](OC3O[C@H](C)C[C@@H]([C@H]3OC(=O)C)N(C)C)[C@@H](C)C[C@]4(CO4)C(=O)[C@H](C)[C@@H](OC(=O)C)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B23 mock treatment 985920.0 -95600.0 -0.47 1032750.0 -49500.0 -0.29 957710.0 -76135.71428571 -0.436066726552548 -0.6912 -0.9827 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 B24 mock treatment 877190.0 -204000.0 -1.0 913720.0 -169000.0 -1.0 940880.0 -92965.71428571 -0.532460424001011 -1.4623 -0.9676 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C01 mock treatment 890320.0 -191000.0 -0.93 1013840.0 -68400.0 -0.41 1029990.0 -3855.71428571001 -0.0220835743496404 -0.7868 -0.7722 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C02 mock treatment 1040600.0 -40900.0 -0.2 1158210.0 76000.0 0.45 932180.0 -101665.71428571 -0.582289608065279 -0.1907 -0.2497 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C03 compound treatment 953840.0 -128000.0 -0.62 1040590.0 -41600.0 -0.25 1012330.0 -21515.71428571 -0.123231090507683 -0.5742 -0.8416 2060055 SpecPlus_000041 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C04 compound treatment 880090.0 -201000.0 -0.98 923380.0 -159000.0 -0.94 958050.0 -75795.71428571 -0.434119379129346 -1.3641 -0.953 2060056 SpecPlus_000042 COc1cc(O)c2c(=O)cc(C)oc2c1CC=C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C05 compound treatment 963930.0 -118000.0 -0.57 1099420.0 17200.0 0.1 937050.0 -96795.71428571 -0.554396719974131 -0.5927 -0.7364 2060057 SpecPlus_000043 COC(=O)C[C@H]1C(C)(C)[C@@H](OC(=O)C)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C06 compound treatment 941650.0 -140000.0 -0.68 976060.0 -106000.0 -0.63 871710.0 -162135.71428571 -0.928631074774048 -1.2951 -0.9853 1352641 SpecPlus_000044 COc1c2ccoc2nc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C07 compound treatment 1056600.0 -24900.0 -0.12 1151130.0 68900.0 0.41 1030580.0 -3265.71428571001 -0.0187043538211441 0.1555 0.3636 1094519 SpecPlus_000045 CC(=O)N1CCCC1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C08 compound treatment 1025080.0 -56400.0 -0.28 1073400.0 -8830.0 -0.05 1006740.0 -27105.71428571 -0.155247773142081 -0.2791 -0.8703 2060058 SpecPlus_000046 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@@H](O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C09 compound treatment 876160.0 -205000.0 -1.0 1106560.0 24300.0 0.14 922560.0 -111285.71428571 -0.637388085157033 -0.8637 -0.7213 2060059 SpecPlus_000047 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](C[C@H]5O[C@]543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C10 compound treatment 1066200.0 -15300.0 -0.07 1224560.0 142000.0 0.85 947000.0 -86845.71428571 -0.497408170383388 0.1583 0.1608 3173478 SpecPlus_000048 C[C@H]1C(=O)CCC2[C@]1(C)CCC3[C@@]2(C)CC[C@@]4(C)C5CC(C)(C)CC[C@]5(C)CC[C@]34C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C11 compound treatment 1061190.0 -20300.0 -0.1 892760.0 -189000.0 -1.13 837490.0 -196355.71428571 -1.12462586542684 -1.3571 -0.8508 2060060 SpecPlus_000049 CC1(C)C2CC(=O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)[C@@]2(C)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C12 compound treatment 993660.0 -87800.0 -0.43 962780.0 -119000.0 -0.71 949290.0 -84555.71428571 -0.484292212738885 -0.9375 -0.9757 2060061 SpecPlus_000050 Cc1cc(=O)c2c(O)c3CCC(C)(C)Oc3cc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C13 compound treatment 1130560.0 49100.0 0.24 1219880.0 138000.0 0.82 1111160.0 77314.28571429 0.442816985477559 0.8667 0.9018 2060062 SpecPlus_000051 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C14 compound treatment 947790.0 -134000.0 -0.65 1009840.0 -72400.0 -0.43 966590.0 -67255.71428571 -0.385206593852467 -0.8481 -0.9726 3054135 SpecPlus_000052 CC(=O)O[C@H]1CC[C@@]2(C)C(CC[C@]3(C)C2CC=C4C5CC(C)(C)CC[C@]5(C)CC[C@]43C)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C15 compound treatment 1005920.0 -75600.0 -0.37 998350.0 -83900.0 -0.5 871600.0 -162245.71428571 -0.929261098940377 -1.0377 -0.9286 2060063 SpecPlus_000053 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](C(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C16 compound treatment 1014560.0 -66900.0 -0.33 1005760.0 -76500.0 -0.45 941280.0 -92565.71428571 -0.530169427032539 -0.7574 -0.9821 3054136 SpecPlus_000054 CC1(C)CC[C@]2(C)CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C17 compound treatment 968880.0 -113000.0 -0.55 938910.0 -143000.0 -0.85 891780.0 -142065.71428571 -0.81368030188096 -1.2795 -0.9839 2060064 SpecPlus_000055 CCC(C)C(=O)OC1[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@](C)([C@@H](CC(=O)OC)C1(C)C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C18 compound treatment 1007260.0 -74200.0 -0.36 1081950.0 -282.0 0.0 912320.0 -121525.71428571 -0.696037607549918 -0.6122 -0.78 2060065 SpecPlus_000056 COC[C@@]12CN(C=O)C3[C@@H]4[C@H](OC)C2[C@]3(C5CC6(O)C(OC(=O)c7ccccc7)C5C4(OC(=O)C)C(O)C6OC)[C@H](C[C@H]1O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C19 compound treatment 1070590.0 -10900.0 -0.05 1023270.0 -59000.0 -0.35 980090.0 -53755.71428571 -0.307885446166534 -0.4109 -0.875 2060066 SpecPlus_000057 COC(=O)CC1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C20 compound treatment 875900.0 -206000.0 -1.0 810170.0 -272000.0 -1.62 851430.0 -182415.71428571 -1.04478462107558 -2.1172 -0.9747 2060067 SpecPlus_000058 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C21 compound treatment 684660.0 -397000.0 -1.94 653090.0 -429000.0 -2.55 645380.0 -388465.71428571 -2.22493443445977 -3.8773 -0.9938 3173485 SpecPlus_000059 OC[C@H]1O[C@H](Oc2cccc3[C@H]([C@@H]4c5cccc(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(=O)O)c8cc(cc(O)c8C(=O)c23)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C22 compound treatment 984720.0 -96800.0 -0.47 1047920.0 -34300.0 -0.2 924740.0 -109105.71428571 -0.62490215167886 -0.7516 -0.9282 2060068 SpecPlus_000060 COC1C(O)C(O[C@H]2CC[C@]3(C=O)C4[C@@H](C[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)OC(=O)C)OC(C)C1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C23 mock treatment 973290.0 -108000.0 -0.53 1079750.0 -2480.0 -0.01 975430.0 -58415.71428571 -0.334575560849234 -0.5069 -0.81 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 C24 mock treatment 882940.0 -199000.0 -0.97 1059540.0 -22700.0 -0.13 793600.0 -240245.71428571 -1.37600550779244 -1.4324 -0.8481 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D01 mock treatment 948810.0 -133000.0 -0.65 1037960.0 -44300.0 -0.26 1101550.0 67704.28571429 0.387775783310017 -0.3024 -0.378 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D02 mock treatment 1009540.0 -72000.0 -0.35 1038900.0 -43300.0 -0.26 1004200.0 -29645.71428571 -0.169795603891879 -0.4498 -0.9615 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D03 compound treatment 453660.0 -628000.0 -3.07 472800.0 -609000.0 -3.62 407000.0 -626845.71428571 -3.59025407782071 -5.9362 -0.9972 2060069 SpecPlus_000061 COc1cc(cc(O)c1OC)c2coc3cc(OCc4ccccc4)c(OC)c(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D04 compound treatment 823470.0 -258000.0 -1.26 930210.0 -152000.0 -0.9 796000.0 -237845.71428571 -1.3622595259816 -2.0363 -0.9863 3173486 SpecPlus_000062 CC(=O)O[C@H]1CC[C@@]2(C)[C@H](CCC3C2CC[C@]4(C)C(CC[C@]34O)C5=CC(=O)OC5)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D05 compound treatment 962460.0 -119000.0 -0.58 1055300.0 -26900.0 -0.16 860360.0 -173485.71428571 -0.993638113754443 -1.0019 -0.8619 2060070 SpecPlus_000063 COc1c(O)cc(O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D06 compound treatment 751690.0 -330000.0 -1.61 940280.0 -142000.0 -0.84 868240.0 -165605.71428571 -0.948505473475543 -1.9653 -0.958 2060071 SpecPlus_000064 CCOC(=O)c1c(C)cc(O)c(C=O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D07 compound treatment 68450.0 -1010000.0 -4.95 75430.0 -1010000.0 -5.99 54630.0 -979215.71428571 -5.60845058227199 -9.5523 -0.997 2060072 SpecPlus_000065 Oc1ccc(cc1)C(C=C)C2=CC(=O)C=CC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D08 compound treatment 928770.0 -153000.0 -0.75 980480.0 -102000.0 -0.61 873370.0 -160475.71428571 -0.919123437354888 -1.3108 -0.9859 2060073 SpecPlus_000066 CC(=O)OCC(OC(=O)C)C(OC(=O)C)C(OC(=O)C)C(OC(=O)C)C(COC(=O)C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D09 compound treatment 327760.0 -754000.0 -3.68 351070.0 -731000.0 -4.35 268530.0 -765315.71428571 -4.38333995338154 -7.1671 -0.997 2060074 SpecPlus_000067 COc1cc2OCC3Oc4c5CC(Oc5cc(OC(=O)C)c4C(=O)C3c2cc1OC)C(=C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D10 compound treatment 1040990.0 -40500.0 -0.2 1024440.0 -57800.0 -0.34 960220.0 -73625.71428571 -0.421690720575385 -0.5561 -0.9607 2060075 SpecPlus_000068 CC(C)CCCC(C)C1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](O)C(C)(C)C4CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D11 compound treatment 954630.0 -127000.0 -0.62 942830.0 -139000.0 -0.83 830100.0 -203745.71428571 -1.16695203441936 -1.5102 -0.9682 2060076 SpecPlus_000069 COc1cc(OC)c2c(=O)cc(oc2c1)c3ccc(OC)c(I)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D12 compound treatment 80890.0 -1000000.0 -4.89 60990.0 -1020000.0 -6.07 57980.0 -975865.71428571 -5.58926348266104 -9.5557 -0.9961 2060077 SpecPlus_000070 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CCC=C4C(=O)c3c(O)c2C=C1)C(C/C=C(\C)/C(=O)O)(OC5(C)C)C(=O)O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D13 compound treatment 1002630.0 -78900.0 -0.39 1268350.0 186000.0 1.11 1113170.0 79324.28571429 0.454329245244131 0.6788 0.5401 1095778 SpecPlus_000071 COc1cc(C)c2c(=O)c3c(O)cc(OC)cc3oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D14 compound treatment 1011000.0 -70500.0 -0.34 998800.0 -83400.0 -0.5 871780.0 -162065.71428571 -0.928230150304565 -1.0212 -0.9221 3054028 SpecPlus_000072 CC(CCC=C(C)C)[C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)C4(C)CC[C@H](O)C(C)(C)C4CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D15 compound treatment 790670.0 -291000.0 -1.42 864760.0 -217000.0 -1.29 793300.0 -240545.71428571 -1.37772375551879 -2.3624 -0.9992 2060078 SpecPlus_000073 COc1cc2OC[C@H]3Oc4c(CC=C(C)C)c(O)ccc4C(=O)[C@H]3c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D16 compound treatment 39750.0 -1040000.0 -5.09 42050.0 -1040000.0 -6.19 32700.0 -1001145.71428571 -5.73405449106847 -9.8203 -0.9969 2060079 SpecPlus_000074 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CC6C=C4C(=O)c3c(O)c2C=C1)C(C/C=C(/C)\C(=O)O)(OC5(C)C)C6O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D17 compound treatment 931130.0 -150000.0 -0.73 987360.0 -94900.0 -0.56 676800.0 -357045.71428571 -2.04497662258629 -1.9305 -0.8599 3054030 SpecPlus_000075 Oc1cc(O)cc(/C=C/c2ccccc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D18 compound treatment 46660.0 -1030000.0 -5.06 54150.0 -1030000.0 -6.11 42140.0 -991705.71428571 -5.67998696261253 -9.7281 -0.997 2060080 SpecPlus_000076 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CC6CC4C(=O)c3c(O)c2C=C1)C(C/C=C(/C)\C(=O)O)(OC5(C)C)C6O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D19 compound treatment 874400.0 -207000.0 -1.01 862570.0 -220000.0 -1.31 857360.0 -176485.71428571 -1.01082059101798 -1.9219 -0.9922 3054032 SpecPlus_000077 COc1cc(C/C=C/c2ccccc2)c(OC)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D20 compound treatment 987160.0 -94300.0 -0.46 1030790.0 -51400.0 -0.31 902630.0 -131215.71428571 -0.751537009111155 -0.8766 -0.9394 2060081 SpecPlus_000078 CC(=CCc1c(O)cc(C)oc1=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D21 compound treatment 38370.0 -1040000.0 -5.1 56600.0 -1030000.0 -6.1 76130.0 -957715.71428571 -5.48530949521662 -9.6307 -0.9973 1092958 SpecPlus_000079 COC1=CC(=O)C(=CC1=O)C(C=C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D22 compound treatment 322100.0 -759000.0 -3.71 268110.0 -814000.0 -4.84 291870.0 -741975.71428571 -4.24966028027119 -7.3907 -0.9942 2060082 SpecPlus_000080 COC(=O)c1cc(OC)c(=O)c2c(OC)c(OC)ccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D23 mock treatment 949120.0 -132000.0 -0.65 1046990.0 -35200.0 -0.21 1004960.0 -28885.71428571 -0.165442709651782 -0.5899 -0.8431 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 D24 mock treatment 1113680.0 32200.0 0.16 1071330.0 -10900.0 -0.06 915730.0 -118115.71428571 -0.676506858393694 -0.3372 -0.4834 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E01 mock treatment 1048370.0 -33100.0 -0.16 1110770.0 28500.0 0.17 1078290.0 44444.28571429 0.254554309593365 0.1515 0.4378 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E02 mock treatment 1172870.0 91400.0 0.45 1164740.0 82500.0 0.49 980330.0 -53515.71428571 -0.306510847985451 0.3641 0.4982 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E03 compound treatment 1065950.0 -15500.0 -0.08 1092320.0 10100.0 0.06 953670.0 -80175.71428571 -0.459205795934116 -0.2743 -0.5846 2060083 SpecPlus_000081 COC(=O)C(O)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E04 compound treatment 1136030.0 54500.0 0.27 1099680.0 17400.0 0.1 896270.0 -137575.71428571 -0.787963860909861 -0.2412 -0.2877 2060084 SpecPlus_000082 C[C@@]12CCC3C(CC[C@H]4CC=CC[C@@]43C)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E05 compound treatment 1033030.0 -48500.0 -0.24 998950.0 -83300.0 -0.5 927200.0 -106645.71428571 -0.610812520322757 -0.7753 -0.9441 2060085 SpecPlus_000083 C[C@]12CCC3[C@@](C)([C@H](O)CC4[C@]3(C)C=CC(=O)OC4(C)C)C25OC5C(=O)O[C@H]1c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E06 compound treatment 1445440.0 364000.0 1.78 1324370.0 242000.0 1.44 978790.0 -55055.71428571 -0.315331186314068 1.6759 0.7256 2060086 SpecPlus_000084 CCC(C)C(=O)O[C@@H]1C[C@@]2(C)[C@@H](OC(=O)CC32OC4(C)OC53[C@H](OC(=O)C(C)C)[C@@]6(O)[C@@H](OC(=O)C7(C)OC7C)[C@@]8(C)C[C@]6(O)[C@@](C)([C@H]8CC(=O)OC)C15O4)c9ccoc9 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E07 compound treatment 1355460.0 274000.0 1.34 1105130.0 22900.0 0.14 905790.0 -128055.71428571 -0.733438133060225 0.428 0.2793 2060087 SpecPlus_000085 COC(=O)C(O)[C@H]1C(C)(C)C(OC(=O)/C(=C/C)/C)[C@@H]2C=C3C(CC[C@@]4(C)[C@@H](OC(=O)CC34)c5ccoc5)[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E08 compound treatment 1123360.0 41900.0 0.2 1036320.0 -45900.0 -0.27 991950.0 -41895.71428571 -0.239957386051336 -0.1781 -0.4269 2060088 SpecPlus_000086 COc1cc2ccc(=O)oc2c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E09 compound treatment 1218370.0 137000.0 0.67 1326350.0 244000.0 1.45 1218680.0 184834.28571429 1.05863697060286 1.8354 0.9574 2060089 SpecPlus_000087 CCC(C)C(=O)O[C@@H]1C[C@@]2(C)[C@@H](OC(=O)CC32OC4(C)O[C@]53[C@H](OC(=O)C)[C@@]6(O)C(OC(=O)C7(C)OC7C)C8(C)CC6(O)[C@@](C)([C@H]8CC(=O)OC)[C@@]15O4)c9ccoc9 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E10 compound treatment 1024190.0 -57300.0 -0.28 989320.0 -92900.0 -0.55 945610.0 -88235.71428571 -0.505369384848828 -0.7724 -0.9662 1000946 SpecPlus_000088 COc1ccc(CC2N(C)CCc3cc(OC)c(OC)cc23)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E11 compound treatment 1026140.0 -55400.0 -0.27 1044480.0 -37800.0 -0.22 897230.0 -136615.71428571 -0.782465468185528 -0.7375 -0.8598 2060090 SpecPlus_000089 COC(=O)C[C@H]1C(C)(C)C(OC(=O)C)[C@]2(O)C=C3C(CC[C@@]4(C)[C@@H](OC(=O)CC34)c5ccoc5)[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E12 compound treatment 1124060.0 42600.0 0.21 972290.0 -110000.0 -0.65 961280.0 -72565.71428571 -0.415619578608934 -0.4973 -0.62 1029487 SpecPlus_000090 OCC(O)Cc1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E13 compound treatment 766410.0 -315000.0 -1.54 831930.0 -250000.0 -1.49 884110.0 -149735.71428571 -0.857610168751413 -2.2433 -0.9725 2060091 SpecPlus_000091 CC(CC(O)C1OC1(C)C)[C@@H]2CCC3(C)C4=CCC5C(C)(C)C(=O)CCC5(C)C4CC[C@@]23C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E14 compound treatment 867010.0 -214000.0 -1.05 839130.0 -243000.0 -1.45 780200.0 -253645.71428571 -1.45275390623625 -2.2784 -0.9898 2060092 SpecPlus_000092 CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CCC3C4CC=C(C(=O)C)[C@@]4(C)C(=O)CC32)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E15 compound treatment 934330.0 -147000.0 -0.72 976730.0 -106000.0 -0.63 1005140.0 -28705.71428571 -0.164411761015969 -0.8723 -0.9008 2060093 SpecPlus_000093 CC([C@@H]1CC[C@]2(C)C3=CCC4C(C)(C)C(=O)CC[C@]4(C)C3CC[C@@]12C)C5OC(C)(C)C(O)C5O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E16 compound treatment 819550.0 -262000.0 -1.28 841920.0 -240000.0 -1.43 784270.0 -249575.71428571 -1.42944301208205 -2.3892 -0.9987 3472730 SpecPlus_000094 CC12CCC3C(CC=C4CC(O)CCC34C)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E17 compound treatment 808270.0 -273000.0 -1.33 865820.0 -216000.0 -1.29 932930.0 -100915.71428571 -0.577993988749394 -1.8474 -0.9512 2060094 SpecPlus_000095 COC(=O)C(O)[C@H]1C(C)(C)[C@@H](OC(=O)C)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E18 compound treatment 959700.0 -122000.0 -0.6 1023200.0 -59000.0 -0.35 836070.0 -197775.71428571 -1.13275890466491 -1.2002 -0.9046 3173612 SpecPlus_000096 CC(=O)OC1CC2(O)C3CCC4CC(CC[C@]4(C)C3CC[C@]2(C)C1C5=CC(=O)OC5)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E19 compound treatment 1155620.0 74100.0 0.36 1076880.0 -5350.0 -0.03 1142930.0 109084.28571429 0.624779419698455 0.5514 0.7629 2060095 SpecPlus_000097 COC(=O)C[C@H]1C(C)(C)[C@@H](O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E20 compound treatment 1090770.0 9280.0 0.05 1004860.0 -77400.0 -0.46 964290.0 -69555.71428571 -0.398379826421182 -0.4695 -0.7693 2060096 SpecPlus_000098 CC(=O)O[C@@H]1CC(=O)[C@@]2(C)C(CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E21 compound treatment 905520.0 -176000.0 -0.86 914680.0 -168000.0 -1.0 838400.0 -195445.71428571 -1.11941384732356 -1.7179 -0.9943 2060097 SpecPlus_000099 C[C@]12CCC3C([C@H](O)CC4C(C)(C)C(=O)C=C[C@]34C)[C@]25O[C@@H]5C[C@H]1c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E22 compound treatment 1015240.0 -66300.0 -0.32 1030490.0 -51700.0 -0.31 935890.0 -97955.71428571 -0.5610406111827 -0.6884 -0.9601 2060098 SpecPlus_000100 C[C@@]12CCC3C(CC[C@H]4C[C@@H](Cl)CC[C@@]43C)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E23 mock treatment 1009700.0 -71800.0 -0.35 1101760.0 19500.0 0.12 1066820.0 32974.28571429 0.188859971522428 -0.0264 -0.0637 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 E24 mock treatment 1098000.0 16500.0 0.08 1020350.0 -61900.0 -0.37 1003410.0 -30435.71428571 -0.174320322904611 -0.2665 -0.6421 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F01 mock treatment 979390.0 -102000.0 -0.5 1211220.0 129000.0 0.77 976220.0 -57625.71428571 -0.330050841836502 -0.0357 -0.0367 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F02 mock treatment 1088580.0 7090.0 0.03 1106650.0 24400.0 0.15 1036260.0 2414.28571428999 0.0138278031311596 0.1118 0.7458 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F03 compound treatment 1037120.0 -44400.0 -0.22 1121540.0 39300.0 0.23 991150.0 -42695.71428571 -0.244539379988281 -0.1314 -0.327 3173615 SpecPlus_000101 CCC(CCC(C)[C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F04 compound treatment 745090.0 -336000.0 -1.64 788320.0 -294000.0 -1.75 673760.0 -360085.71428571 -2.06238819954667 -3.1487 -0.9952 2060099 SpecPlus_000102 Oc1cc(O)c2c(=O)c(coc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F05 compound treatment 701190.0 -380000.0 -1.86 762460.0 -320000.0 -1.9 677280.0 -356565.71428571 -2.04222742622412 -3.3497 -0.9992 2060100 SpecPlus_000103 OC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F06 compound treatment 898780.0 -183000.0 -0.89 914160.0 -168000.0 -1.0 919410.0 -114435.71428571 -0.655429686283751 -1.4708 -0.986 2060101 SpecPlus_000104 COc1ccc(cc1OC)[C@H]2Oc3c(I)c(OC)cc(OC)c3C[C@@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F07 compound treatment 813030.0 -268000.0 -1.31 866040.0 -216000.0 -1.29 880480.0 -153365.71428571 -0.878400966240297 -2.0067 -0.9857 2060102 SpecPlus_000105 COc1ccc2C(=O)c3cc(OC)c(OC)cc3CC(=O)COc2c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F08 compound treatment 706970.0 -375000.0 -1.83 753950.0 -328000.0 -1.95 620480.0 -413365.71428571 -2.36754899574716 -3.5504 -0.9938 2060103 SpecPlus_000106 COc1ccc2C(=O)[C@@H]3[C@@H](COc4cc(OC)c(OC)cc34)Oc2c1CC=C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F09 compound treatment 935230.0 -146000.0 -0.71 1289130.0 207000.0 1.23 898960.0 -134885.71428571 -0.772556906296886 -0.1483 -0.0916 1082584 SpecPlus_000107 COc1cc2OCc3oc4c5CC(Oc5ccc4c(=O)c3-c2cc1OC)C(=C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F10 compound treatment 847900.0 -234000.0 -1.14 827400.0 -255000.0 -1.52 810670.0 -223175.71428571 -1.27823721216289 -2.2718 -0.9931 2060104 SpecPlus_000108 COc1cc(C)c2c(=O)c3c(O)cc(O)cc3oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F11 compound treatment 756210.0 -325000.0 -1.59 653070.0 -429000.0 -2.55 691400.0 -342445.71428571 -1.96135523323706 -3.5234 -0.9815 1105460 SpecPlus_000109 COc1ccc2C3COc4cc(O)ccc4C3Oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F12 compound treatment 1159460.0 78000.0 0.38 978280.0 -104000.0 -0.62 896820.0 -137025.71428571 -0.784813740078212 -0.5901 -0.5519 2060105 SpecPlus_000110 CC1(C)Oc2cc3occ(c4ccc5OCOc5c4)c(=O)c3c(O)c2C=C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F13 compound treatment 972030.0 -109000.0 -0.53 1135730.0 53500.0 0.32 1099840.0 65994.28571429 0.377981771269799 0.0931 0.1279 2060106 SpecPlus_000111 COc1cc(cc(OC)c1OC)c2coc3cc(OC)c(OC)c(OC)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F14 compound treatment 40640.0 -1040000.0 -5.09 41790.0 -1040000.0 -6.19 35770.0 -998075.71428571 -5.71647108933545 -9.8086 -0.9968 2060107 SpecPlus_000112 COC1=C(OC)C(=O)C(=CC1=O)[C@H](C=C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F15 compound treatment 954180.0 -127000.0 -0.62 851040.0 -231000.0 -1.37 854590.0 -179255.71428571 -1.02668574502465 -1.7456 -0.9564 1372522 SpecPlus_000113 COc1ccc(cc1)c2coc3cc(OC)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F16 compound treatment 1079100.0 -2390.0 -0.01 1005200.0 -77000.0 -0.46 939290.0 -94555.71428571 -0.541567136950687 -0.5839 -0.8231 2060108 SpecPlus_000114 CC1=C(Cl)C(=O)C=C(O)C21Oc3cc(O)c(Cl)c(C)c3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F17 compound treatment 1099590.0 18100.0 0.09 962720.0 -120000.0 -0.71 915910.0 -117935.71428571 -0.675475909757881 -0.7493 -0.7611 1539748 SpecPlus_000115 COc1ccccc1c2coc3cc(O)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F18 compound treatment 530530.0 -551000.0 -2.69 491710.0 -591000.0 -3.51 481190.0 -552655.71428571 -3.16533141509335 -5.4091 -0.9943 2060109 SpecPlus_000116 CC(=O)Oc1ccc2C3c4cc(OC(=O)C)c(OC(=O)C)c(OC(=O)C)c4CC3(O)COc2c1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F19 compound treatment 1193600.0 112000.0 0.55 1044880.0 -37400.0 -0.22 1018160.0 -15685.71428571 -0.0898398096922026 0.1361 0.2277 2060110 SpecPlus_000117 COc1ccc(c(OC)c1)c2coc3cc(O)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F20 compound treatment 711860.0 -370000.0 -1.81 702420.0 -380000.0 -2.26 697190.0 -336655.71428571 -1.92819305211842 -3.4599 -0.9955 2060111 SpecPlus_000118 COc1cc(O)c(cc1O)C(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F21 compound treatment 820650.0 -261000.0 -1.27 851590.0 -231000.0 -1.37 772640.0 -261205.71428571 -1.49605374894037 -2.3914 -0.9978 2060112 SpecPlus_000119 COc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F22 compound treatment 1083280.0 1790.0 0.01 1081300.0 -932.0 -0.01 1190680.0 156834.28571429 0.898267182809811 0.5205 0.5794 2060113 SpecPlus_000120 Cc1cc(O)cc(O)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F23 mock treatment 1145600.0 64100.0 0.31 1148050.0 65800.0 0.39 990080.0 -43765.71428571 -0.250667796878944 0.2621 0.4676 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 F24 mock treatment 1063810.0 -17700.0 -0.09 1155050.0 72800.0 0.43 932220.0 -101625.71428571 -0.582060508368432 -0.1359 -0.1861 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G01 mock treatment 1073830.0 -7660.0 -0.04 1174620.0 92400.0 0.55 1021550.0 -12295.71428571 -0.0704236103844016 0.2549 0.4592 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G02 mock treatment 1130880.0 49400.0 0.24 1217070.0 135000.0 0.8 1053010.0 19164.28571429 0.109763301185929 0.6656 0.7882 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G03 compound treatment 994880.0 -86600.0 -0.42 1068670.0 -13600.0 -0.08 940160.0 -93685.71428571 -0.536584218544261 -0.6007 -0.8729 3173736 SpecPlus_000121 C[C@]12CCC3[C@@]4(C)[C@@H](O)C[C@@H](O)C(C)(C)C4C[C@@H](O)[C@@]3(C)C25OC5C[C@H]1c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G04 compound treatment 1062100.0 -19400.0 -0.09 1090130.0 7900.0 0.05 920600.0 -113245.71428571 -0.648613970302546 -0.4021 -0.6118 2060114 SpecPlus_000122 COc1c2OCOc2cc3cc[n+](C)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G05 compound treatment 824870.0 -257000.0 -1.25 904130.0 -178000.0 -1.06 756220.0 -277625.71428571 -1.59009917449615 -2.2534 -0.9861 2060115 SpecPlus_000123 CC(=CCOc1cc2oc(=O)ccc2cc1O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G06 compound treatment 949820.0 -132000.0 -0.64 1040480.0 -41800.0 -0.25 830460.0 -203385.71428571 -1.16489013714773 -1.1873 -0.8771 1019607 SpecPlus_000124 CN(C)Cc1c(C)[nH]c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G07 compound treatment 1245240.0 164000.0 0.8 1120800.0 38600.0 0.23 1004970.0 -28875.71428571 -0.16538543472757 0.4988 0.5879 2060116 SpecPlus_000125 CCC(=O)OC1[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@](C)([C@@H](CC(=O)OC)C1(C)C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G08 compound treatment 981860.0 -99600.0 -0.49 949940.0 -132000.0 -0.79 799140.0 -234705.71428571 -1.3442751997791 -1.5114 -0.9262 2060117 SpecPlus_000126 Cc1ccc2c(CC[C@H]3CC(=O)CC[C@@]32C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G09 compound treatment 1176290.0 94800.0 0.46 1098180.0 15900.0 0.09 960160.0 -73685.71428571 -0.422034370120656 0.0785 0.1239 2060118 SpecPlus_000127 COC(=O)CC1C(C)(C)C(O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G10 compound treatment 1091100.0 9610.0 0.05 1171620.0 89400.0 0.53 953280.0 -80565.71428571 -0.461439517978376 0.0676 0.0958 2060119 SpecPlus_000128 CC(C)c1c(O)c(cc2c1CCC3C(C)(C)CCC[C@@]32C)c4cc5c(CCC6C(C)(C)CCC[C@@]65C)c(C(C)C)c4O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G11 compound treatment 629320.0 -452000.0 -2.21 633920.0 -448000.0 -2.67 613040.0 -420805.71428571 -2.41016153936074 -4.2062 -0.9971 2060120 SpecPlus_000129 OC[C@H]1O[C@H](Oc2cccc3[C@H]([C@H]4c5cccc(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(=O)O)c8cc(cc(O)c8C(=O)c23)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G12 compound treatment 1418990.0 337000.0 1.65 1078880.0 -3350.0 -0.02 957060.0 -76785.71428571 -0.439789596626315 0.6866 0.4023 3054523 SpecPlus_000130 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G13 compound treatment 1256070.0 175000.0 0.85 1171040.0 88800.0 0.53 1253730.0 219884.28571429 1.25938557996522 1.5245 0.9468 2060121 SpecPlus_000131 COC(=O)C[C@H]1C(C)(C)C2(Cl)O[C@]34CC2C(=O)[C@]1(C)C4CC[C@@]5(C)[C@@H](OC(=O)C=C35)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G14 compound treatment 864640.0 -217000.0 -1.06 851790.0 -230000.0 -1.37 827260.0 -206585.71428571 -1.18321811289551 -2.086 -0.9944 2060122 SpecPlus_000132 CC1(C)Oc2cc3oc(=O)ccc3cc2C=C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G15 compound treatment 1054530.0 -27000.0 -0.13 941280.0 -141000.0 -0.84 953510.0 -80335.71428571 -0.460122194721505 -0.8256 -0.8554 2060123 SpecPlus_000133 COC(=O)C[C@H]1C(C)(C)[C@@H](O)[C@@H]2CC3C(CC[C@@]4(C)[C@@H](OC(=O)C=C34)c5ccoc5)[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G16 compound treatment 84190.0 -997000.0 -4.87 343200.0 -739000.0 -4.39 69880.0 -963965.71428571 -5.52110632284899 -8.5381 -0.9956 2060124 SpecPlus_000134 COC(=O)[C@@]1(C)CCC[C@@]2(C)C1CCc3c(C(C)C)c(O)ccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G17 compound treatment 1199620.0 118000.0 0.58 1090110.0 7880.0 0.05 965360.0 -68485.71428571 -0.392251409530519 0.1338 0.1913 2060125 SpecPlus_000135 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2C[C@]3(O)C(CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G18 compound treatment 578460.0 -503000.0 -2.46 554090.0 -528000.0 -3.14 566560.0 -467285.71428571 -2.6763753870972 -4.7774 -0.9947 2060126 SpecPlus_000136 CC(C)c1c(O)ccc2c1CCC3[C@@](C)(CO)CCC[C@@]32C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G19 compound treatment 1157870.0 76400.0 0.37 1059960.0 -22300.0 -0.13 1331310.0 297464.28571429 1.70372444200039 1.1226 0.6418 2060127 SpecPlus_000137 COC1CC2=C3C[C@H]4C(=O)C(C)(C)[C@H](CC(=O)OC)[C@@](C)(C3CC[C@@]2(C)[C@@H](O1)c5ccoc5)C4=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G20 compound treatment 693660.0 -388000.0 -1.89 808560.0 -274000.0 -1.63 654530.0 -379315.71428571 -2.17252787880597 -3.2879 -0.9932 2060128 SpecPlus_000138 CO[C@@H]1C(OC(=O)C(C)C)[C@@]2(C)[C@@H](OC(=O)/C(=C(\OC)/C(C)C)/C2[C@@]34OC5(C)O[C@]14[C@]6(C)[C@@H](CC(=O)OC)C7(C)CC6(O5)[C@](OC)(C7OC(=O)C)[C@H]3OC)c8ccoc8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G21 compound treatment 1229020.0 148000.0 0.72 1026590.0 -55600.0 -0.33 1068360.0 34514.28571429 0.197680309851045 0.3392 0.415 2060129 SpecPlus_000139 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G22 compound treatment 813690.0 -268000.0 -1.31 847040.0 -235000.0 -1.4 879810.0 -154035.71428571 -0.882238386162488 -2.0723 -0.9827 2060130 SpecPlus_000140 COc1ccc(cc1)[C@@H](C)C(=O)c2ccc(O)cc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G23 mock treatment 976970.0 -105000.0 -0.51 1026890.0 -55300.0 -0.33 975570.0 -58275.71428571 -0.333773711910269 -0.6775 -0.9774 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 G24 mock treatment 1157480.0 76000.0 0.37 1089920.0 7690.0 0.05 1164100.0 130254.28571429 0.746030434254841 0.6715 0.8046 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H01 mock treatment 1001840.0 -79700.0 -0.39 1037200.0 -45000.0 -0.27 1079130.0 45284.28571429 0.259365403227156 -0.2295 -0.4259 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H02 mock treatment 1246670.0 165000.0 0.81 1115690.0 33500.0 0.2 1171680.0 137834.28571429 0.789444826807387 1.0366 0.9043 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H03 compound treatment 1043370.0 -38100.0 -0.19 1027680.0 -54600.0 -0.32 926850.0 -106995.71428571 -0.61281714267017 -0.6486 -0.9034 2060131 SpecPlus_000141 CCOC(=O)c1oc2c(OC)c(O)cc(O)c2c(=O)c1c3cc(OC)c(OC)c(OC)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H04 compound treatment 1143070.0 61600.0 0.3 1131850.0 49600.0 0.3 932500.0 -101345.71428571 -0.580456810490501 0.0089 0.0124 2060132 SpecPlus_000142 CC1=CC(=O)C2C(C)(C)CCC[C@]2(C)[C@@]1(O)CCc3ccoc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H05 compound treatment 1054270.0 -27200.0 -0.13 1172850.0 90600.0 0.54 972380.0 -61465.71428571 -0.352044412733834 0.0311 0.0473 2060133 SpecPlus_000143 COc1cc(cc(O)c1OC)c2coc3cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H06 compound treatment 812400.0 -269000.0 -1.31 919630.0 -163000.0 -0.97 786080.0 -247765.71428571 -1.41907625079971 -2.1366 -0.9879 2060134 SpecPlus_000144 COc1cc2ccc(=O)oc2c3ccoc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H07 compound treatment 969120.0 -112000.0 -0.55 1096220.0 14000.0 0.08 952550.0 -81295.71428571 -0.465620587445838 -0.5378 -0.7421 2060135 SpecPlus_000145 COc1c(O)cc2occ(c3ccc(O)cc3)c(=O)c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H08 compound treatment 810270.0 -271000.0 -1.33 810730.0 -272000.0 -1.61 894400.0 -139445.71428571 -0.798674271737468 -2.1583 -0.9652 2060136 SpecPlus_000146 CC(=C)c1cc2cc(C(=O)C)c(O)cc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H09 compound treatment 915580.0 -166000.0 -0.81 929120.0 -153000.0 -0.91 1033030.0 -815.714285710012 -0.00467199738925254 -0.9964 -0.8173 2060137 SpecPlus_000147 COc1ccc(cc1)c2coc3c(OC)c(OC)cc(OC)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H10 compound treatment 975840.0 -106000.0 -0.52 1109820.0 27600.0 0.16 987130.0 -46715.71428571 -0.267563899521425 -0.3578 -0.5922 2060138 SpecPlus_000148 C[C@]1([C@H]2[C@H](C(=O)O)[C@]3(CC(=C)[C@@]4(O)C3)[C@@H](CC4)[C@]52OC1=O)[C@@H](O)C=C5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H11 compound treatment 1157760.0 76300.0 0.37 1074260.0 -7970.0 -0.05 1043740.0 9894.28571428999 0.0566694464415878 0.2205 0.5804 3054572 SpecPlus_000149 CC(=O)O[C@@H]1CC[C@@]2(C)C(CC[C@]3(C)C2CC=C4C5CC(C)(C)CC[C@@]5(CC[C@]43C)C(=O)O)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H12 compound treatment 1476480.0 395000.0 1.93 1030810.0 -51400.0 -0.31 953960.0 -79885.71428571 -0.457544823131974 0.6735 0.3356 1090422 SpecPlus_000150 Cc1cc(O)cc(O)c1C(=O)Oc2cc(C)c(C(=O)O)c(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H13 compound treatment 918360.0 -163000.0 -0.8 1077990.0 -4240.0 -0.03 1029560.0 -4285.71428571001 -0.0245463960907479 -0.4889 -0.6128 2060139 SpecPlus_000151 COc1ccc([C@@H]2COc3c(OC)c(OC)ccc3C2)c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H14 compound treatment 961790.0 -120000.0 -0.58 1030350.0 -51900.0 -0.31 875680.0 -158165.71428571 -0.905892929861962 -1.0388 -0.9262 2060140 SpecPlus_000152 COc1cc2occc2c3oc(=O)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H15 compound treatment 36640.0 -1040000.0 -5.1 42030.0 -1040000.0 -6.19 31100.0 -1002745.71428571 -5.74321847894236 -9.8345 -0.997 2060141 SpecPlus_000153 COC1=CC(=O)C(=CC1=O)C(C=C)c2ccc(OC)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H16 compound treatment 986970.0 -94500.0 -0.46 847590.0 -235000.0 -1.4 934430.0 -99415.71428571 -0.569402750117623 -1.401 -0.8888 1086162 SpecPlus_000154 COc1c2ccoc2c(OC)c3oc(=O)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H17 compound treatment 467160.0 -614000.0 -3.0 405480.0 -677000.0 -4.02 367970.0 -665875.71428571 -3.81379810701938 -6.2583 -0.9926 3173749 SpecPlus_000155 COc1cc2OC[C@H]3Oc4c5CC(Oc5ccc4C(=O)[C@H]3c2cc1OC)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H18 compound treatment 23600.0 -1060000.0 -5.17 22210.0 -1060000.0 -6.3 19280.0 -1014565.71428571 -5.81091743936071 -9.9784 -0.9968 2060142 SpecPlus_000156 CC(=O)OC1C/C(=C/CC/C(=C/CC[C@](C)(O)C2CC1C(=C)C(=O)O2)/C)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H19 compound treatment 40080.0 -1040000.0 -5.09 51440.0 -1030000.0 -6.13 42400.0 -991445.71428571 -5.67849781458303 -9.7551 -0.9971 2060143 SpecPlus_000157 COC1=CC(=O)C(=CC1=O)C(C=C)c2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H20 compound treatment 1107530.0 26000.0 0.13 939790.0 -142000.0 -0.85 953190.0 -80655.71428571 -0.461954992296282 -0.6823 -0.7011 3054620 SpecPlus_000158 COc1c2C=CC(C)(C)Oc2c(CC=C(C)C)c3OCC(=C(O)c13)c4ccc(OC(=O)C)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H21 compound treatment 1147680.0 66200.0 0.32 1129600.0 47400.0 0.28 1028070.0 -5775.71428571001 -0.0330803597983065 0.3302 0.7677 1008719 SpecPlus_000159 COC(=O)C(O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H22 compound treatment 1117230.0 35700.0 0.17 904050.0 -178000.0 -1.06 802210.0 -231635.71428571 -1.32669179804607 -1.2769 -0.7481 2060144 SpecPlus_000160 COc1cccc(c1)c2cc(=O)c3cc(OC)ccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H23 mock treatment 1239640.0 158000.0 0.77 1164920.0 82700.0 0.49 1052740.0 18894.28571429 0.10821687823221 0.7925 0.8593 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 H24 mock treatment 1108760.0 27300.0 0.13 1102170.0 19900.0 0.12 1131120.0 97274.28571429 0.557137734204316 0.467 0.7984 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I01 mock treatment 977200.0 -104000.0 -0.51 1097540.0 15300.0 0.09 982470.0 -51375.71428571 -0.294254014204125 -0.4115 -0.6912 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I02 mock treatment 1215550.0 134000.0 0.65 1215750.0 134000.0 0.79 1019070.0 -14775.71428571 -0.0846277915889286 0.7877 0.7627 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I03 compound treatment 944970.0 -137000.0 -0.67 992000.0 -90200.0 -0.54 872120.0 -161725.71428571 -0.926282802881364 -1.2297 -0.975 2060145 SpecPlus_000161 CC1(C)C2CC(=O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)[C@@]2(C)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I04 compound treatment 969690.0 -112000.0 -0.55 1036430.0 -45800.0 -0.27 900360.0 -133485.71428571 -0.764538416907234 -0.914 -0.9343 2060146 SpecPlus_000162 C[C@@]12CCC(=O)C=C2CCc3ccc(O)cc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I05 compound treatment 1235310.0 154000.0 0.75 1286720.0 204000.0 1.22 1086300.0 52454.28571429 0.300431523887018 1.3094 0.8964 2060147 SpecPlus_000163 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I06 compound treatment 1332610.0 251000.0 1.23 1331080.0 249000.0 1.48 1061760.0 27914.28571429 0.159878859871256 1.655 0.858 2060148 SpecPlus_000164 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C[C@H](O)[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I07 compound treatment 1080760.0 -733.0 0.0 1050650.0 -31600.0 -0.19 1240920.0 207074.28571429 1.18601640204991 0.5742 0.4782 3173867 SpecPlus_000165 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I08 compound treatment 1068000.0 -13500.0 -0.07 1036180.0 -46100.0 -0.27 918240.0 -115605.71428571 -0.662130852416531 -0.5785 -0.8039 2060149 SpecPlus_000166 Cc1cc(O)c2C(=O)c3c(O)cccc3Cc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I09 compound treatment 1166720.0 85200.0 0.42 1133450.0 51200.0 0.3 1128540.0 94694.28571429 0.542360803757671 0.7294 0.9744 2060150 SpecPlus_000167 CC1(C)[C@H](O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]3(C)OC(=O)CC12)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I10 compound treatment 1101470.0 20000.0 0.1 1052660.0 -29600.0 -0.18 1186000.0 152154.28571429 0.871462518278688 0.458 0.512 2060151 SpecPlus_000168 COC(=O)[C@@H]1OC(=O)C2OC23[C@@]1(C)CCC4[C@@]5(C)[C@H](C[C@@H](OC(=O)C)C(C)(C)C5C[C@H](O)[C@]43C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I11 compound treatment 1159420.0 77900.0 0.38 1118950.0 36700.0 0.22 1058970.0 25124.28571429 0.143899156016163 0.429 0.9287 2060152 SpecPlus_000169 CC(=O)O[C@@H]1CC2C(C)(C)C=CC(=O)[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I12 compound treatment 1161300.0 79800.0 0.39 1011810.0 -70400.0 -0.42 876500.0 -157345.71428571 -0.901196386076594 -0.537 -0.503 2060153 SpecPlus_000170 COc1cccc2c1CCC3=CC(=O)CC[C@@]32C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I13 compound treatment 1109120.0 27600.0 0.13 1147680.0 65400.0 0.39 1015700.0 -18145.71428571 -0.103929441048306 0.2426 0.5711 2060154 SpecPlus_000171 CC(=O)O[C@H]1CC[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I14 compound treatment 1324590.0 243000.0 1.19 1000730.0 -81500.0 -0.48 1334400.0 300554.28571429 1.72142239358183 1.3998 0.652 2060155 SpecPlus_000172 COC(=O)[C@@H]1OC(=O)C2OC23[C@@]1(C)CCC4[C@@]5(C)[C@H](C[C@@H](OC(=O)C)C(C)(C)C5C[C@@H](O)[C@]43C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I15 compound treatment 339040.0 -742000.0 -3.63 318990.0 -763000.0 -4.54 302080.0 -731765.71428571 -4.19118258265094 -7.1345 -0.9959 2060156 SpecPlus_000173 CCC(C)C(O)C(=O)O[C@H]1[C@H](OC=O)C(C(=C)C2(O)C(=O)C[C@@H](c3ccoc3)[C@]12C)[C@]4(C)C(CC(=O)OC)[C@@](C)(COC(=O)C)OC(=O)C[C@@H]4OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I16 compound treatment 1172900.0 91400.0 0.45 1032530.0 -49700.0 -0.3 1037480.0 3634.28571428999 0.0208153438849995 0.0992 0.1851 2060157 SpecPlus_000174 CC(=O)C1CCC2C3CCC4C[C@H](O)CCC4(C)C3C[C@H](O)C12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I17 compound treatment 1161070.0 79600.0 0.39 1043120.0 -39100.0 -0.23 964850.0 -68995.71428571 -0.395172430665321 -0.138 -0.2295 2060158 SpecPlus_000175 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](OC(=O)C)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I18 compound treatment 1025970.0 -55500.0 -0.27 989520.0 -92700.0 -0.55 988590.0 -45255.71428571 -0.259201760586502 -0.6246 -0.9366 2060159 SpecPlus_000176 COC(=O)[C@@H]1OC(=O)C2OC23[C@@]1(C)CCC4[C@@]5(C)CCC(=O)C(C)(C)C5C[C@@H](OC(=O)C)[C@]43C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I19 compound treatment 185540.0 -896000.0 -4.38 226720.0 -856000.0 -5.09 244610.0 -789235.71428571 -4.52034157209617 -8.0743 -0.9978 2060160 SpecPlus_000177 CC(=O)O[C@@H]1CC2C(C)(C)CCC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I20 compound treatment 851570.0 -230000.0 -1.12 875930.0 -206000.0 -1.23 986750.0 -47095.71428571 -0.269740346641474 -1.5126 -0.8976 2060161 SpecPlus_000178 CC(=C)[C@H]1COc2cc3oc(=O)ccc3cc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I21 compound treatment 1211720.0 130000.0 0.64 1129880.0 47600.0 0.28 1037360.0 3514.28571428999 0.0201280447944579 0.5426 0.7786 2060162 SpecPlus_000179 COC(=O)C[C@H]1C(C)(C)[C@@H](O)[C@@H]2CC3=C4C=C(OC)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I22 compound treatment 954210.0 -127000.0 -0.62 907010.0 -175000.0 -1.04 1008060.0 -25785.71428571 -0.147687483146123 -1.0459 -0.8556 3054675 SpecPlus_000180 CC(C)CCCC(C)C1CCC2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCCC12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I23 mock treatment 1173800.0 92300.0 0.45 1041030.0 -41200.0 -0.25 1187520.0 153674.28571429 0.880168306758882 0.6271 0.6155 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 I24 mock treatment 1167370.0 85900.0 0.42 1016400.0 -65800.0 -0.39 1023430.0 -10415.71428571 -0.0596559246325828 -0.0182 -0.0316 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J01 mock treatment 1154720.0 73200.0 0.36 1081760.0 -472.0 0.0 1121070.0 87224.28571429 0.499576435371455 0.4934 0.8029 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J02 mock treatment 1113600.0 32100.0 0.16 1248440.0 166000.0 0.99 1050300.0 16454.28571429 0.0942417967245301 0.7156 0.7119 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J03 compound treatment 1012860.0 -68600.0 -0.34 1016750.0 -65500.0 -0.39 1137180.0 103334.28571429 0.591846338276669 -0.0767 -0.0979 2060163 SpecPlus_000181 COc1ccc2C(=O)[C@@H]3[C@@H](COc4cc(OC)c(OC)cc34)Oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J04 compound treatment 1412910.0 331000.0 1.62 1298500.0 216000.0 1.29 1241440.0 207594.28571429 1.18899469810892 2.3638 0.991 2060164 SpecPlus_000182 CC12CCC3C(CC3(C)C)C(=O)CCC2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J05 compound treatment 1185790.0 104000.0 0.51 1105860.0 23600.0 0.14 989440.0 -44405.71428571 -0.254333392028499 0.2285 0.3895 2060165 SpecPlus_000183 COc1cc2OCc3oc4c5CC(Oc5ccc4c(=O)c3-c2cc1OC)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J06 compound treatment 1092220.0 10700.0 0.05 951250.0 -131000.0 -0.78 1023250.0 -10595.71428571 -0.0606868732683952 -0.4545 -0.5804 2060166 SpecPlus_000184 CC1(C)CC2C1CCC(=C)/C(=N\O)/CCC2=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J07 compound treatment 538210.0 -543000.0 -2.65 595850.0 -486000.0 -2.89 540030.0 -493815.71428571 -2.82832576103111 -4.8353 -0.9994 2060167 SpecPlus_000185 COC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J08 compound treatment 1026010.0 -55500.0 -0.27 912210.0 -170000.0 -1.01 939880.0 -93965.71428571 -0.538187916422191 -1.051 -0.8929 2060168 SpecPlus_000186 C/C(=C/CC1[C@](C)(O)CC[C@H]2C(C)(C)CCC[C@]12C)/C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J09 compound treatment 543610.0 -538000.0 -2.63 527570.0 -555000.0 -3.3 514440.0 -519405.71428571 -2.97489229208911 -5.1391 -0.9958 2060169 SpecPlus_000187 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4c5c(O)c(O)c(O)cc5[C@H]6Oc7cc(O)cc(O)c7C[C@H]6OC(=O)c8cc(O)c(O)c(O)c8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J10 compound treatment 970050.0 -111000.0 -0.54 956380.0 -126000.0 -0.75 962840.0 -71005.71428571 -0.406684690431893 -0.9812 -0.9706 2060170 SpecPlus_000188 CC(=O)OC1CCC2(O)CC1(C)CCC3C2CC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J11 compound treatment 77960.0 -1000000.0 -4.9 72900.0 -1010000.0 -6.0 59080.0 -974765.71428571 -5.58296324099774 -9.5194 -0.9966 2060171 SpecPlus_000189 COC(=O)/C(=C\CC1(OC(C)(C)C2CC3C=C4C(=O)c5c(O)c6C7CC(C)(CCC7=C(C)C)Oc6c(CCC(C)(C)Cl)c5OC241)C3=O)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J12 compound treatment 1519840.0 438000.0 2.14 1173320.0 91100.0 0.54 1104660.0 70814.28571429 0.405588284739888 1.7834 0.794 2060172 SpecPlus_000190 CC1(C)CC2C1CCC3(CBr)CCC4C(CC(=O)O)C(=O)OC24C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J13 compound treatment 53150.0 -1030000.0 -5.02 46460.0 -1040000.0 -6.16 39360.0 -994485.71428571 -5.69590939154341 -9.7454 -0.9966 449 SpecPlus_000191 CC1=CC(=O)c2ccccc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J14 compound treatment 1058780.0 -22700.0 -0.11 877130.0 -205000.0 -1.22 1126720.0 92874.28571429 0.531936767551123 -0.4611 -0.3454 2060173 SpecPlus_000192 CC(C)C1CCC(C)(O)C2CCC(=CC12)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J15 compound treatment 819790.0 -262000.0 -1.28 674940.0 -407000.0 -2.42 679470.0 -354375.71428571 -2.02968421782174 -3.3084 -0.9705 2060174 SpecPlus_000193 CC(=CCc1c2OC(C)(C)C=Cc2c(O)c3c(=O)c(O)c(oc13)c4ccccc4)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J16 compound treatment 1046770.0 -34700.0 -0.17 910500.0 -172000.0 -1.02 924860.0 -108985.71428571 -0.624214852588318 -1.0479 -0.8669 2060175 SpecPlus_000194 C[C@](O)(CCC1C(=C)CCC2[C@@](C)(CO)CCC[C@]12C)C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J17 compound treatment 635140.0 -446000.0 -2.18 614320.0 -468000.0 -2.78 565170.0 -468675.71428571 -2.68433660156264 -4.4153 -0.9947 3173879 SpecPlus_000195 CC(=CCc1c2OC(C)(C)C=Cc2c(OC(=O)C)c3c(=O)c(OC(=O)C)c(oc13)c4ccccc4)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J18 compound treatment 1141460.0 60000.0 0.29 1081880.0 -352.0 0.0 938480.0 -95365.71428571 -0.546206405811844 -0.1474 -0.2378 2060176 SpecPlus_000196 CC(=O)/C=C\[C@H]1[C@](C)(O)CCC2C(C)(C)CCC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J19 compound treatment 39600.0 -1040000.0 -5.09 38630.0 -1040000.0 -6.21 35170.0 -998675.71428571 -5.71990758478816 -9.8243 -0.9968 1017609 SpecPlus_000197 CC(=CCc1c(O)c2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc(O)cc4)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J20 compound treatment 1016270.0 -65200.0 -0.32 919640.0 -163000.0 -0.97 906750.0 -127095.71428571 -0.727939740335892 -1.1625 -0.9289 1107153 SpecPlus_000198 CC(=O)c1cc2C=CC(C)(C)Oc2cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J21 compound treatment 951530.0 -130000.0 -0.63 772260.0 -310000.0 -1.84 811900.0 -221945.71428571 -1.27119239648484 -2.1647 -0.9301 1112405 SpecPlus_000199 COc1cc2OCOc2cc1c3cc4cc5ccoc5cc4oc3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J22 compound treatment 847090.0 -234000.0 -1.15 773710.0 -309000.0 -1.83 722210.0 -311635.71428571 -1.78489119174049 -2.751 -0.981 1019872 SpecPlus_000200 COc1cc2COC(=O)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J23 mock treatment 1209440.0 128000.0 0.63 1139100.0 56900.0 0.34 1056970.0 23124.28571429 0.132444171173802 0.6326 0.875 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 J24 mock treatment 1262760.0 181000.0 0.89 1112850.0 30600.0 0.18 1117120.0 83274.28571429 0.476952840307793 0.8918 0.8724 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K01 mock treatment 1143910.0 62400.0 0.3 1230610.0 148000.0 0.88 1256510.0 222664.28571429 1.27530800889611 1.4218 0.8996 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K02 mock treatment 1112430.0 30900.0 0.15 1097290.0 15100.0 0.09 1181130.0 147284.28571429 0.84356963018754 0.626 0.7265 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K03 compound treatment 1248550.0 167000.0 0.82 1218450.0 136000.0 0.81 1150760.0 116914.28571429 0.669625685356296 1.3255 0.9961 2060177 SpecPlus_000201 CC1(C)C2C[C@@H](O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)[C@@]2(C)[C@H]7O[C@H]7C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K04 compound treatment 1323110.0 242000.0 1.18 1067890.0 -14300.0 -0.09 1147680.0 113834.28571429 0.651985008699061 1.0087 0.7465 2060178 SpecPlus_000202 CC12C[C@@H](O)C3C(CCC4CC(O)CCC43C)C2(O)CCC1C5=CC(=O)OC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K05 compound treatment 1198190.0 117000.0 0.57 1219920.0 138000.0 0.82 1103430.0 69584.28571429 0.398543469061836 1.032 0.9605 2060179 SpecPlus_000203 COc1cccc2c1CCC3CC(=O)CC[C@@]32C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K06 compound treatment 1156740.0 75200.0 0.37 1256700.0 174000.0 1.04 1044550.0 10704.28571429 0.0613087153027437 0.8466 0.768 2060180 SpecPlus_000204 CC1=CCC2[C@@]3(C)[C@@H](O)[C@@H](O)CC(C)(C)C3CC4OC(=O)C=C1[C@]42C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K07 compound treatment 1066140.0 -15400.0 -0.08 1147840.0 65600.0 0.39 971370.0 -62475.71428571 -0.357829180079226 -0.0247 -0.0461 2060181 SpecPlus_000205 COc1ccc2c(CC=C3C(C)(C)C(O)CC[C@@]32C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K08 compound treatment 1308720.0 227000.0 1.11 1057120.0 -25100.0 -0.15 1037170.0 3324.28571428999 0.0190398212344336 0.5657 0.505 3173991 SpecPlus_000206 C[C@@]12CCC3C(CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]2(O)C[C@H](O)[C@@H]1C5=CC(=O)OC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K09 compound treatment 1344810.0 263000.0 1.29 1031360.0 -50900.0 -0.3 1130810.0 96964.28571429 0.555362211553751 0.8888 0.62 2060182 SpecPlus_000207 COc1ccc2c(CCC3C(C)(C)CCC[C@@]32C)c1C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K10 compound treatment 1205510.0 124000.0 0.61 1057560.0 -24700.0 -0.15 1136960.0 103114.28571429 0.590586289944009 0.6061 0.7058 2060183 SpecPlus_000208 CC12C(CCC2(O)C3CCC4CC(O)CCC4(C)C3CC1O)C5=CC(=O)OC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K11 compound treatment 540980.0 -541000.0 -2.64 595260.0 -487000.0 -2.9 538570.0 -495275.71428571 -2.83668789996603 -4.8344 -0.9992 3173992 SpecPlus_000209 CC(C)c1c(O)ccc2c1CCC3C(C)(C)CCC[C@@]32C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K12 compound treatment 916800.0 -165000.0 -0.8 770250.0 -312000.0 -1.86 856160.0 -177685.71428571 -1.0176935819234 -2.1233 -0.9379 2060184 SpecPlus_000210 CC1CCc2c(O)c3c(=O)cc(C)oc3cc2OC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K13 compound treatment 1065230.0 -16300.0 -0.08 875170.0 -207000.0 -1.23 1050500.0 16654.28571429 0.0953872952087661 -0.7017 -0.567 3173993 SpecPlus_000211 O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2[C@H]1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K14 compound treatment 1207970.0 126000.0 0.62 1023310.0 -58900.0 -0.35 1115890.0 82044.28571429 0.469908024629742 0.4258 0.4999 2060185 SpecPlus_000212 COc1ccc2[C@@H]3COc4cc(OC)ccc4[C@@H]3Oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K15 compound treatment 1127220.0 45700.0 0.22 963040.0 -119000.0 -0.71 1090680.0 56834.28571429 0.325517940691788 -0.0923 -0.1138 1051795 SpecPlus_000213 CC(=O)OC1CCC2(C=O)C3CCC4(C)C(CCC4(O)C3CCC2(O)C1)C5=CC(=O)OC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K16 compound treatment 1221710.0 140000.0 0.69 994480.0 -87800.0 -0.52 958730.0 -75115.71428571 -0.430224684282944 -0.1541 -0.1601 2060186 SpecPlus_000214 CC(=O)OC1CCC2(C3CCC4(C)C(CCC54OC2=O)C6=CC(=O)OC6)C(O)(CCC35)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K17 compound treatment 1025950.0 -55500.0 -0.27 825950.0 -256000.0 -1.52 1028040.0 -5805.71428571001 -0.0332521845709419 -1.0558 -0.6819 3053987 SpecPlus_000215 CC(=O)C1CC[C@H]2C3CC[C@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K18 compound treatment 1129070.0 47600.0 0.23 981310.0 -101000.0 -0.6 1249810.0 215964.28571429 1.2369338096742 0.5019 0.3599 2060187 SpecPlus_000216 COc1cccc(/C=C/C(=O)O)c1C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K19 compound treatment 1221040.0 140000.0 0.68 900870.0 -181000.0 -1.08 1184530.0 150684.28571429 0.863043104419553 0.2693 0.1748 2060188 SpecPlus_000217 C[C@H]1C2C(CC3C4CCC5C[C@@H](O)CCC5(C)C4=CCC23C)OC61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K20 compound treatment 47050.0 -1030000.0 -5.05 41800.0 -1040000.0 -6.19 41400.0 -992445.71428571 -5.68422530700421 -9.7718 -0.9966 3173995 SpecPlus_000218 C[C@H]1C2C(O[C@@]31CC[C@@H](C)CO3)C(O)C4C5CC[C@H]6C[C@H](O[C@@H]7O[C@H](CO)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O[C@@H]9OC[C@@H](O)[C@H](O)[C@H]9O)[C@H]8O[C@@H]%10O[C@H](CO)[C@H](O)[C@H](O[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)[C@H]%10O)[C@H](O)[C@H]7O)[C@H](O)C[C@]6(C)C5CC[C@]24C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K21 compound treatment 1115540.0 34000.0 0.17 1020220.0 -62000.0 -0.37 1143260.0 109414.28571429 0.626669492197445 0.2449 0.3284 2060189 SpecPlus_000219 C[C@H]1C2C(CC3C4CC[C@H]5C[C@@H](O)CCC5(C)C4C[C@@H](O)C23C)OC61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K22 compound treatment 1408530.0 327000.0 1.6 1002310.0 -79900.0 -0.48 1006660.0 -27185.71428571 -0.155705972535775 0.5582 0.3334 2060190 SpecPlus_000220 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@H](CC[C@]5(C)C4C(=O)[C@@H](OC(=O)C)[C@]23C)OC(=O)C)O[C@@]61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K23 mock treatment 975810.0 -106000.0 -0.52 1056320.0 -25900.0 -0.15 1010960.0 -22885.71428571 -0.1310777551247 -0.4628 -0.8344 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 K24 mock treatment 1286210.0 205000.0 1.0 1140210.0 58000.0 0.34 1117090.0 83244.28571429 0.476781015535158 1.0518 0.9064 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L01 mock treatment 1016980.0 -64500.0 -0.32 1071650.0 -10600.0 -0.06 1109790.0 75944.28571429 0.434970320860542 0.0328 0.0607 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L02 mock treatment 1418100.0 337000.0 1.64 1125020.0 42800.0 0.25 1112870.0 79024.28571429 0.452610997517777 1.3577 0.7873 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L03 compound treatment 1382590.0 301000.0 1.47 1367540.0 285000.0 1.7 1162000.0 128154.28571429 0.734002700170362 2.2527 0.9535 3173997 SpecPlus_000221 COC(=O)CC1C(C)(C)C(=O)C=CC1(C)C2CC[C@@]3(C)[C@@H](OC(=O)C4OC43C2=C)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L04 compound treatment 1304610.0 223000.0 1.09 1201500.0 119000.0 0.71 1036720.0 2874.28571428999 0.0164624496449025 1.0484 0.806 2060191 SpecPlus_000222 CC1(C)CC2C1CCC(=O)C(CCC2=C)C3CC(=O)OC3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L05 compound treatment 1318570.0 237000.0 1.16 1090410.0 8180.0 0.05 981450.0 -52395.71428571 -0.300096056473729 0.5236 0.4372 2070 SpecPlus_000223 COc1ccc(cc1)c2coc3cc(O)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L06 compound treatment 988610.0 -92900.0 -0.45 900990.0 -181000.0 -1.08 833220.0 -200625.71428571 -1.14908225806527 -1.5477 -0.944 2060192 SpecPlus_000224 CC1(C)CC2C1CCC3(C)CCCC2(O)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L07 compound treatment 1418240.0 337000.0 1.65 1137410.0 55200.0 0.33 1029800.0 -4045.71428571001 -0.0231717979096647 1.126 0.6711 3173998 SpecPlus_000225 CC(=O)O[C@@H]1C2CC[C@@H]3C1(C[C@@]2(C)O)C[C@@H](O)[C@@]4(O)[C@@H](C[C@H](O)C4(C)C)[C@]3(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L08 compound treatment 1520440.0 439000.0 2.14 1319720.0 237000.0 1.41 991900.0 -41945.71428571 -0.240243760672396 1.9148 0.7425 2060193 SpecPlus_000226 CC1(C)C2CC1C(=C)C(N)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L09 compound treatment 1123130.0 41600.0 0.2 1102740.0 20500.0 0.12 1069240.0 35394.28571429 0.202720503181684 0.3049 0.9772 2060194 SpecPlus_000227 COc1cc(O)c(C(=O)O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L10 compound treatment 1333610.0 252000.0 1.23 1012130.0 -70100.0 -0.42 1021540.0 -12305.71428571 -0.0704808853086134 0.4298 0.33 2060195 SpecPlus_000228 CC1(C)CC23C1CCC3(C)C(O)CCC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L11 compound treatment 1009880.0 -71600.0 -0.35 968160.0 -114000.0 -0.68 1000200.0 -33645.71428571 -0.1927055735766 -0.7049 -0.8954 2060196 SpecPlus_000229 COc1cc2OCC3Oc4cc5OC(C)(C)C=Cc5c(O)c4C(=O)C3c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L12 compound treatment 1002840.0 -78700.0 -0.38 910990.0 -171000.0 -1.02 925410.0 -108435.71428571 -0.621064731756669 -1.1684 -0.9323 2060197 SpecPlus_000230 COC1(C)CCC2OC2(C)CCC3C1CC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L13 compound treatment 1090720.0 9230.0 0.05 1082660.0 428.0 0.0 949280.0 -84565.71428571 -0.484349487663097 -0.2521 -0.5183 2060198 SpecPlus_000231 COc1ccc2C=C3c4cc(OC)c(OC)cc4OCC3(O)Oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L14 compound treatment 1302500.0 221000.0 1.08 947600.0 -135000.0 -0.8 1083320.0 49474.28571429 0.283363596471901 0.3248 0.2364 2060199 SpecPlus_000232 CC1(C)CC2C1CCC3(C)OC2(C)CCC3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L15 compound treatment 1041840.0 -39700.0 -0.19 1117890.0 35700.0 0.21 958910.0 -74935.71428571 -0.429193735647131 -0.2372 -0.4594 3054042 SpecPlus_000233 COc1ccc(/C=C/C(=O)O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L16 compound treatment 1020160.0 -61300.0 -0.3 1020910.0 -61300.0 -0.36 961640.0 -72205.71428571 -0.413557681337309 -0.6223 -0.9917 2060200 SpecPlus_000234 CC12CCC3C(CC3(C)C)C(C)(O)CCC2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L17 compound treatment 957000.0 -124000.0 -0.61 817030.0 -265000.0 -1.58 885040.0 -148805.71428571 -0.852283600799715 -1.7537 -0.9264 2060201 SpecPlus_000235 CC(=O)OCC(O)CC(O)CCCCCCCCCCCC#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L18 compound treatment 1365360.0 284000.0 1.39 957330.0 -125000.0 -0.74 1240520.0 206674.28571429 1.18372540508143 1.0553 0.536 2060202 SpecPlus_000236 CC1(C)CC2C1CCC3(C)OC2(C)CCC3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L19 compound treatment 1256370.0 175000.0 0.85 1036380.0 -45900.0 -0.27 1010460.0 -23385.71428571 -0.13394150133529 0.2585 0.2851 2060203 SpecPlus_000237 CCOC(=O)c1c(C)cc(O)c(C)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L20 compound treatment 718030.0 -363000.0 -1.78 602210.0 -480000.0 -2.85 707400.0 -326445.71428571 -1.86971535449817 -3.7528 -0.9756 2060204 SpecPlus_000238 CC(=O)OC1CC(C)(C)C2CCC3(C)CC12CCC3OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L21 compound treatment 1304480.0 223000.0 1.09 1107460.0 25200.0 0.15 1012080.0 -21765.71428571 -0.124662963612978 0.6436 0.5815 1049467 SpecPlus_000239 COC(=O)c1c(C)cc(OC(=O)c2c(C)cc(O)c(C=O)c2O)c(C)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L22 compound treatment 1032410.0 -49100.0 -0.24 995170.0 -87100.0 -0.52 1003450.0 -30395.71428571 -0.174091223207764 -0.5379 -0.9017 3054095 SpecPlus_000240 CCC(/C=C/[C@@H](C)[C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L23 mock treatment 1098100.0 16600.0 0.08 1018280.0 -64000.0 -0.38 1002260.0 -31585.71428571 -0.180906939188968 -0.2772 -0.6463 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 L24 mock treatment 1233790.0 152000.0 0.74 1138560.0 56300.0 0.33 908580.0 -125265.71428571 -0.717458429205132 0.2088 0.1921 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M01 mock treatment 1121410.0 39900.0 0.2 1237920.0 156000.0 0.93 1028040.0 -5805.71428571001 -0.0332521845709419 0.6279 0.6633 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M02 mock treatment 1219400.0 138000.0 0.67 1090510.0 8280.0 0.05 1077970.0 44124.28571429 0.252721512018587 0.5633 0.781 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M03 compound treatment 1033470.0 -48000.0 -0.23 1196290.0 114000.0 0.68 1023600.0 -10245.71428571 -0.0586822509209821 0.2222 0.3086 3173999 SpecPlus_000241 C[C@H]1C2C(CC3C4CC[C@H]5CC(CCC5(C)C4CC(=O)C23C)OC(=O)C)OC61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M04 compound treatment 1112180.0 30700.0 0.15 1117530.0 35300.0 0.21 1016800.0 -17045.71428571 -0.0976291993850077 0.1514 0.5489 3174000 SpecPlus_000242 C[C@H]1[C@H]2[C@H](CC3C4CC[C@@H]5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M05 compound treatment 1334260.0 253000.0 1.23 1221210.0 139000.0 0.83 1214560.0 180714.28571429 1.0350397018276 1.7877 0.9872 3054097 SpecPlus_000243 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CC[C@@H](C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M06 compound treatment 1221920.0 140000.0 0.69 1061400.0 -20800.0 -0.12 1239890.0 206044.28571429 1.18011708485609 1.0059 0.7339 2060205 SpecPlus_000244 C[C@H]1[C@H]2[C@H](CC3C4CC[C@@H]5CC(=O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M07 compound treatment 1417510.0 336000.0 1.64 1020020.0 -62200.0 -0.37 1028250.0 -5595.71428571001 -0.032049411162494 0.7158 0.4252 1002679 SpecPlus_000245 OCC(O)C(O)C(O)C(O)C(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M08 compound treatment 1421960.0 340000.0 1.66 1278000.0 196000.0 1.16 1019050.0 -14795.71428571 -0.0847423414373522 1.5836 0.7793 2060206 SpecPlus_000246 CCC(CCC(C)C1CCC2C3CC=C4C[C@H](CC[C@]4(C)C3CC[C@]12C)OC(=O)C)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M09 compound treatment 1409920.0 328000.0 1.6 1272030.0 190000.0 1.13 1307130.0 273284.28571429 1.56523367525625 2.4817 0.9889 2060207 SpecPlus_000247 CC1(C)[C@H](O)C[C@H](O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M10 compound treatment 979220.0 -102000.0 -0.5 998730.0 -83500.0 -0.5 1219310.0 185464.28571429 1.0622452908282 0.0381 0.0299 1071570 SpecPlus_000248 CCOC(=O)c1c(C)cc(O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M11 compound treatment 1331040.0 250000.0 1.22 1086830.0 4600.0 0.03 1363110.0 329264.28571429 1.88585870099392 1.8085 0.8053 2060208 SpecPlus_000249 COC(=O)C[C@H]1C(C)(C)[C@@H](O)[C@@H]2CC3=C4CC(O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M12 compound treatment 1408480.0 327000.0 1.6 1166460.0 84200.0 0.5 972240.0 -61605.71428571 -0.352846261672799 1.0078 0.589 2060209 SpecPlus_000250 COc1cc2OCC3Oc4c(C(=O)O)c(O)ccc4C(=O)C3(O)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M13 compound treatment 1126580.0 45100.0 0.22 1065990.0 -16200.0 -0.1 1225830.0 191984.28571429 1.0995885414143 0.7063 0.6275 2060210 SpecPlus_000251 CC(=O)O[C@@H]1CC2C(C)(C)C3(CC[C@]2(C)C4CC[C@@]5(C)[C@@H](OC(=O)C6OC65[C@]14C)c7ccoc7)SCCS3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M14 compound treatment 50770.0 -1030000.0 -5.04 44710.0 -1040000.0 -6.17 47700.0 -986145.71428571 -5.64814210475077 -9.7305 -0.9966 2060211 SpecPlus_000252 CC[C@@]1(O)C[C@H](OC2C[C@H](C(O)C(C)O2)N(C)C)c3c(O)c4C(=O)c5c(O)ccc(O)c5C(=O)c4cc3[C@H]1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M15 compound treatment 1277790.0 196000.0 0.96 1020280.0 -62000.0 -0.37 1069150.0 35304.28571429 0.202205028863777 0.4578 0.4372 2060212 SpecPlus_000253 CC1(C)[C@H](O)CC(=O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M16 compound treatment 811320.0 -270000.0 -1.32 684220.0 -398000.0 -2.37 697280.0 -336565.71428571 -1.92767757780052 -3.2415 -0.9747 1010377 SpecPlus_000254 Oc1ccc2C3c4cc(O)c(O)cc4CC3(O)COc2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M17 compound treatment 1050560.0 -30900.0 -0.15 1054880.0 -27400.0 -0.16 1043170.0 9324.28571428999 0.053404775761515 -0.1503 -0.6583 2060213 SpecPlus_000255 CC1(C)C2CC(=O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)[C@@]2(C)[C@H]6O[C@H]6C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M18 compound treatment 788130.0 -293000.0 -1.43 747680.0 -335000.0 -1.99 728070.0 -305775.71428571 -1.75132808615238 -2.9873 -0.9914 2060214 SpecPlus_000256 COc1c(ccc2OC(C)(C)C=Cc12)c3coc4cc5OC(C)(C)C(O)Cc5cc4c3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M19 compound treatment 1042470.0 -39000.0 -0.19 799940.0 -282000.0 -1.68 896030.0 -137815.71428571 -0.789338459090944 -1.535 -0.8232 2069251 SpecPlus_000257 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C[C@H](O)[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M20 compound treatment 414400.0 -667000.0 -3.26 406610.0 -676000.0 -4.02 391200.0 -642645.71428571 -3.68074845807536 -6.3264 -0.9964 1010376 SpecPlus_000258 Oc1ccc2C3c4cc(O)c(O)cc4CC3(O)COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M21 compound treatment 598240.0 -483000.0 -2.36 572910.0 -509000.0 -3.03 634040.0 -399805.71428571 -2.28988419851595 -4.4339 -0.9917 2060215 SpecPlus_000259 CC1(C)C2C=C[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)[C@@]2(C)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M22 compound treatment 792770.0 -289000.0 -1.41 695770.0 -386000.0 -2.3 717550.0 -316295.71428571 -1.81158130642319 -3.1872 -0.9811 2060216 SpecPlus_000260 COc1cc2OC[C@H]3Oc4c(ccc5oc(cc45)C(C)C)C(=O)[C@H]3c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M23 mock treatment 1083250.0 1760.0 0.01 1038850.0 -43400.0 -0.26 1010610.0 -23235.71428571 -0.133082377472113 -0.2208 -0.7604 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 M24 mock treatment 1093230.0 11700.0 0.06 1037870.0 -44400.0 -0.26 943280.0 -90565.71428571 -0.518714442190178 -0.4187 -0.716 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N01 mock treatment 1044410.0 -37100.0 -0.18 1060050.0 -22200.0 -0.13 1208700.0 174854.28571429 1.00147659623948 0.3974 0.3873 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N02 mock treatment 1375920.0 294000.0 1.44 1032990.0 -49200.0 -0.29 1154300.0 120454.28571429 0.689901008527274 1.0598 0.6534 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N03 compound treatment 758090.0 -323000.0 -1.58 687790.0 -394000.0 -2.35 656440.0 -377405.71428571 -2.16158836828152 -3.5145 -0.9873 2060217 SpecPlus_000261 COc1c(ccc2OC(C)(C)CCc12)C3COc4cc5OC(C)(C)C(O)Cc5cc4C3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N04 compound treatment 1207520.0 126000.0 0.62 1193920.0 112000.0 0.66 1104640.0 70794.28571429 0.405473734891464 0.9731 0.9806 1072288 SpecPlus_000262 CC(=C)C1CNC(C1CC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N05 compound treatment 937090.0 -144000.0 -0.71 914980.0 -167000.0 -0.99 845200.0 -188645.71428571 -1.08046689885954 -1.6054 -0.9854 2060218 SpecPlus_000263 COc1c(CC(=O)c2cc3CC(O)C(C)(C)Oc3cc2O)ccc4OC(C)(C)C=Cc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N06 compound treatment 1363620.0 282000.0 1.38 1177890.0 95700.0 0.57 1257500.0 223654.28571429 1.28097822639307 1.8638 0.9481 3053934 SpecPlus_000264 CC(CCC=C(C)C)C1CC[C@@]2(C)C3=C(CCC12C)C4(C)CCC(OC(=O)C)C(C)(C)C4CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N07 compound treatment 1443960.0 362000.0 1.77 1324360.0 242000.0 1.44 1336830.0 302984.28571429 1.7353402001653 2.8556 0.996 3174115 SpecPlus_000265 CC[C@H](CCC(C)[C@H]1CCC2C3CCC4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N08 compound treatment 992860.0 -88600.0 -0.43 902330.0 -180000.0 -1.07 1030910.0 -2935.71428571001 -0.0168142813221546 -0.8774 -0.7601 2060219 SpecPlus_000266 CC(=O)OC/1CCC(=C)[C@H]2CC(C)(C)[C@@H]2C\C=C1/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N09 compound treatment 888230.0 -193000.0 -0.94 938160.0 -144000.0 -0.86 879470.0 -154375.71428571 -0.884185733585689 -1.5503 -0.9992 1001923 SpecPlus_000267 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N10 compound treatment 1212650.0 131000.0 0.64 874320.0 -208000.0 -1.24 978240.0 -55605.71428571 -0.318481307145717 -0.5277 -0.3694 1114909 SpecPlus_000268 COc1cc(CC=C)ccc1OC(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N11 compound treatment 904000.0 -177000.0 -0.87 793960.0 -288000.0 -1.71 794730.0 -239115.71428571 -1.3695334413565 -2.2811 -0.9669 907310 SpecPlus_000269 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N12 compound treatment 1381870.0 300000.0 1.47 1080870.0 -1360.0 -0.01 1194240.0 160394.28571429 0.918657055829213 1.373 0.793 2060220 SpecPlus_000270 CC/1[C@H]2C[C@@H](C\C1=N/O)C2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N13 compound treatment 1252600.0 171000.0 0.84 1165870.0 83600.0 0.5 1059170.0 25324.28571429 0.145044654500399 0.8536 0.8679 2060221 SpecPlus_000271 COc1ccc(cc1)[C@H]2Oc3cc(OC)cc(OC)c3C[C@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N14 compound treatment 1215130.0 134000.0 0.65 1029250.0 -53000.0 -0.32 1179360.0 145514.28571429 0.833431968602051 0.6762 0.6122 2060222 SpecPlus_000272 C/C/1=C\CCC(=O)C2CC(C)(C)C2CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N15 compound treatment 1389280.0 308000.0 1.5 1018950.0 -63300.0 -0.38 1033380.0 -465.714285710012 -0.00266737504183946 0.6494 0.4189 2060223 SpecPlus_000273 COc1cc(OC)c2C[C@H](O)[C@H](Oc2c1)c3ccc(OC)c(OC)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N16 compound treatment 1120760.0 39300.0 0.19 962470.0 -120000.0 -0.71 977450.0 -56395.71428571 -0.32300602615845 -0.4869 -0.6047 1099943 SpecPlus_000274 COc1c2C=CC(C)(C)Oc2c(CC=C(C)C)c3oc(=O)c(c(O)c13)c4ccc(O)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N17 compound treatment 813300.0 -268000.0 -1.31 767760.0 -314000.0 -1.87 736170.0 -297675.71428571 -1.70493539754082 -2.8205 -0.9898 2060224 SpecPlus_000275 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4ccc(O)c(O)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N18 compound treatment 1200390.0 119000.0 0.58 1074880.0 -7350.0 -0.04 1287680.0 253834.28571429 1.45383394766429 1.1495 0.734 3174120 SpecPlus_000276 CCCCCCCCCCCC[C@@H]([C@@H](C)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N19 compound treatment 611570.0 -470000.0 -2.3 601630.0 -481000.0 -2.86 618420.0 -415425.71428571 -2.37934763013479 -4.3493 -0.9952 1859 SpecPlus_000277 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N20 compound treatment 1217760.0 136000.0 0.67 1046680.0 -35600.0 -0.21 1026770.0 -7075.71428571001 -0.0405260999458408 0.2389 0.3415 2060225 SpecPlus_000278 COC(=O)c1c(C)c2Oc3c(Cl)c(OC(=O)C)c(Cl)c(C)c3C(=O)Oc2c(C)c1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N21 compound treatment 428800.0 -653000.0 -3.19 429570.0 -653000.0 -3.88 417960.0 -615885.71428571 -3.52748076088458 -6.1185 -0.9968 2060226 SpecPlus_000279 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c4c(=O)c(O)cc(cc34)[C@H]5Oc6cc(O)cc(O)c6C[C@H]5OC(=O)c7cc(O)c(O)c(O)c7 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N22 compound treatment 1223390.0 142000.0 0.69 1029010.0 -53200.0 -0.32 1224720.0 190874.28571429 1.09323102482679 0.8487 0.6369 2060227 SpecPlus_000280 COC(=O)C[C@H](OC(=O)C)[C@@]1(C)[C@@H](C[C@@H](OC(=O)C)[C@]2(C)C1CC[C@@]3(C)[C@@H](CC=C32)C4COC(=O)C4)C(=C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N23 mock treatment 1096910.0 15400.0 0.08 1011610.0 -70600.0 -0.42 1130420.0 96574.28571429 0.55312848950949 0.1204 0.1723 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 N24 mock treatment 1199470.0 118000.0 0.58 1085120.0 2890.0 0.02 1017360.0 -16485.71428571 -0.0944218036291468 0.2882 0.4932 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O01 mock treatment 1020450.0 -61000.0 -0.3 1087000.0 4770.0 0.03 1129800.0 95954.28571429 0.549577444208359 0.1615 0.258 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O02 mock treatment 1332360.0 251000.0 1.23 1104530.0 22300.0 0.13 1281800.0 247954.28571429 1.42015629222775 1.6041 0.853 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O03 compound treatment 962130.0 -119000.0 -0.58 830800.0 -251000.0 -1.5 822260.0 -211585.71428571 -1.21185557500141 -1.8996 -0.9446 2060228 SpecPlus_000281 COC(=O)CC1[C@@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]53O[C@]2(O)[C@@H]([C@H]5OC(=O)C)C(OC(=O)C)C1(C)C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O04 compound treatment 640610.0 -441000.0 -2.15 650240.0 -432000.0 -2.57 654340.0 -379505.71428571 -2.17361610236599 -3.9817 -0.9966 2060229 SpecPlus_000282 Oc1cc(OC(=O)c2cc(O)c(O)c(O)c2)c3C[C@@H](OC(=O)c4cc(O)c(O)c(O)c4)[C@H](Oc3c1)c5cc(O)c(O)c(O)c5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O05 compound treatment 1163600.0 82100.0 0.4 1226100.0 144000.0 0.86 1146420.0 112574.28571429 0.644768368248374 1.0978 0.9597 2060230 SpecPlus_000283 CC(=O)O[C@H]1C[C@@H](O)C(C)(C)C2C[C@@H](OC(=O)C)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6)[C@@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O06 compound treatment 1383230.0 302000.0 1.47 1134960.0 52700.0 0.31 1150880.0 117034.28571429 0.670312984446838 1.4192 0.8603 2060231 SpecPlus_000284 COc1cc(OC)c(cc1OC)c2coc3cc(O)c(OC)c(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O07 compound treatment 1276260.0 195000.0 0.95 1214320.0 132000.0 0.79 1059910.0 26064.28571429 0.149282998892072 1.0891 0.8762 2060232 SpecPlus_000285 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O08 compound treatment 1104330.0 22800.0 0.11 1010480.0 -71800.0 -0.43 1164320.0 130474.28571429 0.7472904825875 0.2495 0.2876 1051460 SpecPlus_000286 COc1cc(C(=O)O)c2Oc3c(C=O)c(O)cc(C)c3C(=O)Oc2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O09 compound treatment 1414840.0 333000.0 1.63 1041180.0 -41100.0 -0.24 1163840.0 129994.28571429 0.744541286225334 1.2292 0.6801 2060233 SpecPlus_000287 COC(=O)C[C@H]1C(C)(C)[C@H](O)[C@@H]2CC3=C4CC(O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O10 compound treatment 1395430.0 314000.0 1.53 1023880.0 -58400.0 -0.35 1010300.0 -23545.71428571 -0.134857900122679 0.6074 0.3848 2060234 SpecPlus_000288 COC(=O)c1c(C)c2Oc3c(Cl)c(O)c(Cl)c(C)c3C(=O)Oc2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O11 compound treatment 1367680.0 286000.0 1.4 1058330.0 -23900.0 -0.14 1285410.0 251564.28571429 1.44083253986821 1.5571 0.7736 2060235 SpecPlus_000289 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)[C@@H]3O[C@@H]3[C@]2(C)C4CC[C@@]5(C)[C@@H](OC(=O)C=C5[C@]14C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O12 compound treatment 1379750.0 298000.0 1.46 1141370.0 59100.0 0.35 1285330.0 251484.28571429 1.44037434047452 1.876 0.9024 2060236 SpecPlus_000290 COc1cc(OC)c2C[C@H](OS(=O)(=O)c3ccc(C)cc3)[C@H](Oc2c1)c4ccc(OC)c(OC)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O13 compound treatment 1062760.0 -18700.0 -0.09 997760.0 -84500.0 -0.5 1060350.0 26504.28571429 0.151803095557391 -0.2552 -0.4791 2060237 SpecPlus_000291 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)C(=O)O)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O14 compound treatment 1182470.0 101000.0 0.49 1081800.0 -432.0 0.0 1101660.0 67814.28571429 0.388405807476347 0.5076 0.8084 2060238 SpecPlus_000292 Cc1cc(O)cc(O)c1C(=O)Oc2cc(C)c(C(=O)Oc3cc(C)c(C(=O)O)c(O)c3)c(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O15 compound treatment 1164410.0 82900.0 0.41 1007200.0 -75000.0 -0.45 1000910.0 -32935.71428571 -0.188639053957562 -0.1326 -0.21 2060239 SpecPlus_000293 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](CC=C4[C@]13C)C5CO[C@H]([C@H](O)C5)C(C)(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O16 compound treatment 67630.0 -1010000.0 -4.95 56080.0 -1030000.0 -6.1 48920.0 -984925.71428571 -5.64115456399693 -9.6399 -0.9964 1057125 SpecPlus_000294 CC(C)(C=C)c1c2OC(C)(C)C=Cc2c(O)c3c(=O)c4ccc(O)c(O)c4oc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O17 compound treatment 1098400.0 16900.0 0.08 997760.0 -84500.0 -0.5 991230.0 -42615.71428571 -0.244081180594586 -0.3832 -0.6788 2060240 SpecPlus_000295 CC1=C2C(O)C(=O)OC3CC4C(C)(C)C(=O)C=C[C@]4(C)C(CC1)[C@@]32C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O18 compound treatment 803770.0 -278000.0 -1.36 702010.0 -380000.0 -2.26 670200.0 -363645.71428571 -2.08277807256608 -3.2913 -0.9795 3174236 SpecPlus_000296 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c4c(=O)c(O)cc(cc34)[C@H]5Oc6cc(O)cc(O)c6C[C@H]5O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O19 compound treatment 1065460.0 -16000.0 -0.08 895960.0 -186000.0 -1.11 948020.0 -85825.71428571 -0.491566128113784 -0.9686 -0.7976 2060241 SpecPlus_000297 CC1(C)C2C[C@@H](O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)[C@@]2(C)CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O20 compound treatment 1033880.0 -47600.0 -0.23 962830.0 -119000.0 -0.71 899840.0 -134005.71428571 -0.767516712966248 -0.9874 -0.9218 2060242 SpecPlus_000298 COc1ccc(cc1)c2cc(=O)c3c(O)c(OC)c(O[C@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O21 compound treatment 1157790.0 76300.0 0.37 1053540.0 -28700.0 -0.17 1081790.0 47944.28571429 0.274600533067496 0.2753 0.5578 2060243 SpecPlus_000299 CC1(C)[C@@H]2O[C@@H]2C(=O)[C@@]3(C)C1CC(=O)[C@]4(C)C3CC[C@@]5(C)[C@@H](OC(=O)C6OC654)c7ccoc7 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O22 compound treatment 1076320.0 -5170.0 -0.03 867210.0 -215000.0 -1.28 967630.0 -66215.71428571 -0.37925000173444 -0.9718 -0.7285 2060244 SpecPlus_000300 COC1=CC(=O)OC(CCc2ccc(OC)c(OC)c2)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O23 mock treatment 1287070.0 206000.0 1.0 1031800.0 -50400.0 -0.3 1137180.0 103334.28571429 0.591846338276669 0.7485 0.6218 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 O24 mock treatment 930340.0 -151000.0 -0.74 828220.0 -254000.0 -1.51 965220.0 -68625.71428571 -0.393053258469484 -1.5254 -0.8834 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P01 mock treatment 1033770.0 -47700.0 -0.23 1038900.0 -43300.0 -0.26 996160.0 -37685.71428571 -0.215844642958168 -0.408 -0.9974 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P02 mock treatment 1186600.0 105000.0 0.51 1128580.0 46300.0 0.28 1159710.0 125864.28571429 0.720886742525859 0.8718 0.9405 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P03 compound treatment 681920.0 -400000.0 -1.95 555210.0 -527000.0 -3.13 701370.0 -332475.71428571 -1.90425213379789 -4.0359 -0.9715 2069225 SpecPlus_000301 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c5c(=O)c(O)cc(cc45)[C@H]6Oc7cc(O)cc(O)c7C[C@H]6OC(=O)c8cc(O)c(O)c(O)c8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P04 compound treatment 1317520.0 236000.0 1.15 1140740.0 58500.0 0.35 1078170.0 44324.28571429 0.253867010502823 1.0132 0.8231 2060245 SpecPlus_000302 OC[C@H]1O[C@@](CO)(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P05 compound treatment 1208060.0 127000.0 0.62 1000190.0 -82000.0 -0.49 1099470.0 65624.28571429 0.375862599073962 0.2924 0.335 3054057 SpecPlus_000303 CC(=CCC/C(=C/CCC(C)(O)C=C)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P06 compound treatment 97480.0 -984000.0 -4.81 66720.0 -1020000.0 -6.04 62260.0 -971585.71428571 -5.56474981509839 -9.4751 -0.9957 2060246 SpecPlus_000304 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C/C=C/3\[C@H](O)COC3=O)C(=C)CCC12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P07 compound treatment 696110.0 -385000.0 -1.88 638350.0 -444000.0 -2.64 661630.0 -372215.71428571 -2.13186268261559 -3.8419 -0.9901 425 SpecPlus_000305 Oc1ccc(cc1)c2coc3cc(O)cc(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P08 compound treatment 1223740.0 142000.0 0.69 1172490.0 90300.0 0.54 1038880.0 5034.28571428999 0.0288338332746518 0.7278 0.8283 1984013 SpecPlus_000306 C/C=C/c1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P09 compound treatment 1054360.0 -27100.0 -0.13 1019850.0 -62400.0 -0.37 905570.0 -128275.71428571 -0.734698181392885 -0.7149 -0.8575 1016781 SpecPlus_000307 OC(=O)c1cc(O)c(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P10 compound treatment 1227380.0 146000.0 0.71 1039680.0 -42600.0 -0.25 1018580.0 -15265.71428571 -0.0874342628753069 0.215 0.2823 1001982 SpecPlus_000308 Nc1nc2[nH]c(=O)cnc2c(=O)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P11 compound treatment 1151220.0 69700.0 0.34 1141050.0 58800.0 0.35 1084160.0 50314.28571429 0.288174690105693 0.565 0.9966 2060247 SpecPlus_000309 COc1cc(OC)c2C[C@@H](O)[C@H](Oc2c1)c3ccc(OC)c(OC)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P12 compound treatment 1246110.0 165000.0 0.8 1088570.0 6340.0 0.04 1160960.0 127114.28571429 0.728046108052335 0.9065 0.835 3054108 SpecPlus_000310 Nc1nc2ncc(=O)[nH]c2c(=O)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P13 compound treatment 612320.0 -469000.0 -2.29 558200.0 -524000.0 -3.12 585440.0 -448405.71428571 -2.56824033018531 -4.6054 -0.9918 653 SpecPlus_000311 Oc1cc2cccc(O)c(=O)c2c(O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P14 compound treatment 615490.0 -466000.0 -2.28 569870.0 -512000.0 -3.05 579200.0 -454645.71428571 -2.60397988289348 -4.577 -0.9929 1053058 SpecPlus_000312 COc1cc(OC)c2c(=O)c(O)c(oc2c1)c3ccc(OC)c(OC)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P15 compound treatment 204020.0 -877000.0 -4.29 189620.0 -893000.0 -5.31 226640.0 -807205.71428571 -4.62326461090478 -8.209 -0.996 1210108 SpecPlus_000313 Oc1ccc2cccc(O)c(=O)c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P16 compound treatment 1201710.0 120000.0 0.59 1194420.0 112000.0 0.67 959570.0 -74275.71428571 -0.425413590649152 0.4787 0.4858 3174242 SpecPlus_000314 OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P17 compound treatment 846570.0 -235000.0 -1.15 760960.0 -321000.0 -1.91 879420.0 -154425.71428571 -0.884472108206748 -2.2763 -0.9493 2060248 SpecPlus_000315 OC1=Cc2c(O)cc(O)cc2OC1(O)c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P18 compound treatment 1074720.0 -6770.0 -0.03 1089700.0 7470.0 0.04 924010.0 -109835.71428571 -0.629083221146321 -0.3567 -0.5648 1952709 SpecPlus_000316 COc1ccc2c(C)cc(=O)oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P19 compound treatment 1125070.0 43600.0 0.21 1082410.0 178.0 0.0 999840.0 -34005.71428571 -0.194767470848224 0.0111 0.0384 2060249 SpecPlus_000317 COc1ccc(cc1)c2coc3c(OC)c(O)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P20 compound treatment 1191270.0 110000.0 0.54 1139850.0 57600.0 0.34 1102400.0 68554.28571429 0.39264415186802 0.7342 0.9817 3047 SpecPlus_000318 C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)C(=C3[C@H]2OC1=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P21 compound treatment 1188200.0 107000.0 0.52 1098690.0 16500.0 0.1 963740.0 -70105.71428571 -0.401529947252831 0.1257 0.1889 2060250 SpecPlus_000319 COc1cc(C(=O)O)c(O)c2OCOc21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P22 compound treatment 975220.0 -106000.0 -0.52 903680.0 -179000.0 -1.06 888960.0 -144885.71428571 -0.829831830508689 -1.3919 -0.9638 1009294 SpecPlus_000320 Oc1ccc2C(=O)c3ccccc3C(=O)c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P23 mock treatment 1129730.0 48200.0 0.24 1119780.0 37500.0 0.22 1080410.0 46564.28571429 0.266696593526267 0.419 0.9972 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1081 P24 mock treatment 926950.0 -155000.0 -0.76 964250.0 -118000.0 -0.7 993770.0 -40075.71428571 -0.229533349844788 -0.9735 -0.9219 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A01 mock treatment 847730.0 -193000.0 -0.94 908540.0 -170000.0 -1.01 847520.0 -79389.0625 -0.454700253793354 -1.3898 -0.9556 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A02 mock treatment 902470.0 -138000.0 -0.67 835270.0 -243000.0 -1.45 805870.0 -121039.0625 -0.69325031313551 -1.6247 -0.9336 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A03 compound treatment 892920.0 -147000.0 -0.72 922400.0 -156000.0 -0.93 860270.0 -66639.0625 -0.381674725423306 -1.1726 -0.9487 1025940 SpecPlus_000321 Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A04 compound treatment 964670.0 -75700.0 -0.37 835750.0 -243000.0 -1.44 825840.0 -101069.0625 -0.578872289484541 -1.3815 -0.8638 1112402 SpecPlus_000322 COc1ccc2ccc(=O)oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A05 compound treatment 898830.0 -142000.0 -0.69 798690.0 -280000.0 -1.66 789360.0 -137549.0625 -0.787811213009196 -1.8151 -0.9227 3054266 SpecPlus_000323 CC(CCC=C(C)C)C1CC[C@@]2(C)C3=C(CC[C@]12C)C4(C)CCC(O)C(C)(C)C4CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A06 compound treatment 1016190.0 -24100.0 -0.12 911520.0 -167000.0 -0.99 995440.0 68530.9375 0.392510425147626 -0.4152 -0.3863 3174244 SpecPlus_000324 N=c1[nH]c(=O)c2[nH]c(=O)c(=O)[nH]c2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A07 compound treatment 965450.0 -74900.0 -0.37 922080.0 -157000.0 -0.93 893530.0 -33379.0625 -0.191178327494851 -0.8591 -0.8436 3174245 SpecPlus_000325 OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc3ccc(O)cc3)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A08 compound treatment 968360.0 -72000.0 -0.35 813760.0 -265000.0 -1.58 907170.0 -19739.0625 -0.113055330869953 -1.1777 -0.7279 3054270 SpecPlus_000326 COC(=O)[C@@H]1C(O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A09 compound treatment 1028200.0 -12100.0 -0.06 901300.0 -177000.0 -1.05 906750.0 -20159.0625 -0.115460877686849 -0.7097 -0.668 2359 SpecPlus_000327 CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@@H]32)n1c5ccccc45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A10 compound treatment 1029130.0 -11200.0 -0.05 942600.0 -136000.0 -0.81 1063680.0 136770.9375 0.783354507968965 -0.0464 -0.0411 2060251 SpecPlus_000328 NCC(N)C(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A11 compound treatment 35120.0 -1010000.0 -4.91 29240.0 -1050000.0 -6.24 51270.0 -875639.0625 -5.01521609415811 -9.3339 -0.9938 2060252 SpecPlus_000329 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3O[C@]4(C5C[C@H]6C=C4C(=O)c3c(OC(=O)C)c2C=C1)C(C/C=C(\C)/C(=O)O)(OC5(C)C)C6=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A12 compound treatment 1021760.0 -18600.0 -0.09 817530.0 -261000.0 -1.55 935150.0 8240.9375 0.04719990707467 -0.9216 -0.5923 2060253 SpecPlus_000330 NC(CC(=O)c1ccccc1N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A13 compound treatment 1034930.0 -5410.0 -0.03 861800.0 -217000.0 -1.29 939200.0 12290.9375 0.0703962513804499 -0.719 -0.5567 2060254 SpecPlus_000331 CC(=O)CC1CCCCN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A14 compound treatment 966370.0 -74000.0 -0.36 780250.0 -298000.0 -1.77 831360.0 -95549.0625 -0.547256531319626 -1.549 -0.8189 599 SpecPlus_000332 Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A15 compound treatment 960480.0 -79900.0 -0.39 807360.0 -271000.0 -1.61 820860.0 -106049.0625 -0.607395201742019 -1.5073 -0.8529 647 SpecPlus_000333 Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A16 compound treatment 423540.0 -617000.0 -3.01 395400.0 -683000.0 -4.06 294680.0 -632229.0625 -3.62108716391863 -6.1762 -0.9928 1020463 SpecPlus_000334 Oc1cc2ccc(=O)oc2cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A17 compound treatment 637610.0 -403000.0 -1.97 640870.0 -438000.0 -2.6 625720.0 -301189.0625 -1.72505807281113 -3.6349 -0.9848 2060255 SpecPlus_000335 CC(=O)Oc1ccc(/C=C/c2cc(OC(=O)C)cc(OC(=O)C)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A18 compound treatment 895200.0 -145000.0 -0.71 878160.0 -200000.0 -1.19 904280.0 -22629.0625 -0.129607783967164 -1.1725 -0.8416 812 SpecPlus_000336 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3c(C2=O)c(OC)cc(OC)c3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A19 compound treatment 1073370.0 33000.0 0.16 913550.0 -165000.0 -0.98 881760.0 -45149.0625 -0.258590913292143 -0.6229 -0.606 2060256 SpecPlus_000337 CC(=CC1C(CO)C1(C)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A20 compound treatment 1045600.0 5260.0 0.03 826050.0 -253000.0 -1.5 904130.0 -22779.0625 -0.130466907830341 -0.9276 -0.6152 3174249 SpecPlus_000338 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A21 compound treatment 990500.0 -49800.0 -0.24 856720.0 -222000.0 -1.32 918080.0 -8829.0625 -0.0505683885548766 -0.9316 -0.6938 2060257 SpecPlus_000339 CC1(C)[C@H](O)C[C@H](O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A22 compound treatment 1059840.0 19500.0 0.1 859450.0 -219000.0 -1.3 917870.0 -9039.0625 -0.0517711619633244 -0.7274 -0.5562 3054588 SpecPlus_000340 COC(=O)c1c(C)c2Oc3c(Cl)c(O)c(Cl)c(C)c3C(=O)Oc2c(C)c1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A23 mock treatment 988880.0 -51500.0 -0.25 907430.0 -171000.0 -1.02 962040.0 35130.9375 0.201212178280206 -0.6167 -0.5776 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 A24 mock treatment 887220.0 -153000.0 -0.75 780360.0 -298000.0 -1.77 944900.0 17990.9375 0.103042958181177 -1.3965 -0.7244 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B01 mock treatment 1002030.0 -38300.0 -0.19 1056840.0 -21800.0 -0.13 947630.0 20720.9375 0.118679012490999 -0.1143 -0.4454 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B02 mock treatment 1021360.0 -19000.0 -0.09 1014560.0 -64100.0 -0.38 823840.0 -103069.0625 -0.590327274326902 -0.6143 -0.8668 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B03 compound treatment 713350.0 -327000.0 -1.6 750560.0 -328000.0 -1.95 697350.0 -229559.0625 -1.31479779068199 -2.8078 -0.9874 2060258 SpecPlus_000341 CC(=O)O[C@H]1Cc2c(OC(=O)C)cc(OC(=O)C)cc2O[C@@H]1c3ccc(OC(=O)C)c(OC(=O)C)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B04 compound treatment 941230.0 -99100.0 -0.48 960800.0 -118000.0 -0.7 821820.0 -105089.0625 -0.601896809017686 -1.0316 -0.9891 2060259 SpecPlus_000342 COc1ccc2c(=O)c(CC(=O)O)coc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B05 compound treatment 964760.0 -75600.0 -0.37 882780.0 -196000.0 -1.16 823040.0 -103869.0625 -0.594909268263846 -1.2291 -0.9045 2060260 SpecPlus_000343 COc1ccc(cc1)C2CC(=O)c3ccc(OC)cc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B06 compound treatment 1038670.0 -1670.0 -0.01 979970.0 -98700.0 -0.59 909700.0 -17209.0625 -0.0985647750443669 -0.4003 -0.6729 2476 SpecPlus_000344 CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B07 compound treatment 1083240.0 42900.0 0.21 881920.0 -197000.0 -1.17 853890.0 -73019.0625 -0.418216127070436 -0.7958 -0.6317 3054634 SpecPlus_000345 COc1c(CC=C(C)C)c2OC(C)(C)C=Cc2c3oc(=O)c(c(O)c13)c4ccc(O)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B08 compound treatment 1029030.0 -11300.0 -0.06 949570.0 -129000.0 -0.77 977640.0 50730.9375 0.290561060050618 -0.3072 -0.3735 2477 SpecPlus_000346 CCOP(=S)(OCC)SCSP(=S)(OCC)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B09 compound treatment 502150.0 -538000.0 -2.63 485410.0 -593000.0 -3.53 474980.0 -451929.0625 -2.58842028037984 -5.0492 -0.9891 1059133 SpecPlus_000347 COc1ccc(C(=O)c2ccccc2)c(O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B10 compound treatment 1025440.0 -14900.0 -0.07 884160.0 -194000.0 -1.16 855570.0 -71339.0625 -0.408593939802853 -0.9456 -0.7696 2478 SpecPlus_000348 COP(=S)(OC)Oc1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B11 compound treatment 951620.0 -88700.0 -0.43 881280.0 -197000.0 -1.17 917880.0 -9029.0625 -0.0517138870391126 -0.9577 -0.7648 2060261 SpecPlus_000349 CC(C)(O)[C@H]1CC[C@@]2(C)[C@H]1CC[C@@]3(C)[C@@H]2CCC4[C@@]5(C)CCCC(C)(C)C5[C@@H](O)C[C@]43C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B12 compound treatment 963710.0 -76600.0 -0.37 823220.0 -255000.0 -1.52 886920.0 -39989.0625 -0.229037052398853 -1.2253 -0.775 2479 SpecPlus_000350 CCOP(=S)(OCC)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B13 compound treatment 870260.0 -170000.0 -0.83 791040.0 -288000.0 -1.71 710110.0 -216799.0625 -1.24171498738773 -2.184 -0.9617 2060262 SpecPlus_000351 CC1(C)CC[C@@]2([C@@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C2C1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B14 compound treatment 1292660.0 252000.0 1.23 1042490.0 -36100.0 -0.21 1072370.0 145460.9375 0.833126417109021 1.0687 0.7109 2480 SpecPlus_000352 COP(=S)(OC)SCn1nnc2ccccc2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B15 compound treatment 791380.0 -249000.0 -1.22 662740.0 -416000.0 -2.47 676320.0 -250589.0625 -1.43524695629941 -2.9588 -0.9522 2060263 SpecPlus_000353 COc1ccc(C(=O)c2ccc(O)cc2)c(O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B16 compound treatment 856240.0 -184000.0 -0.9 704160.0 -374000.0 -2.23 762310.0 -164599.0625 -0.942739883002121 -2.3492 -0.9106 2481 SpecPlus_000354 CCOP(=S)(OCC)SCCSCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B17 compound treatment 777670.0 -263000.0 -1.28 795230.0 -283000.0 -1.69 712570.0 -214339.0625 -1.22762535603163 -2.4227 -0.9895 1034509 SpecPlus_000355 Cc1cc(=O)c2COc3cc(O)c(O)c(C(=O)O)c3-c2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B18 compound treatment 1111010.0 70700.0 0.35 1000930.0 -77700.0 -0.46 932850.0 5940.9375 0.0340266745059554 -0.0478 -0.0827 2482 SpecPlus_000356 CCOC(=O)/C=C(\C)/OP(=O)(OC)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B19 compound treatment 1062950.0 22600.0 0.11 824320.0 -254000.0 -1.51 842090.0 -84819.0625 -0.485800537640362 -1.0898 -0.6845 3174361 SpecPlus_000357 CCC/C=C/C=C/[C@@H]1C[C@@H](O)[C@@H](O)C(=O)[C@H]1C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B20 compound treatment 1055780.0 15400.0 0.08 974200.0 -104000.0 -0.62 993820.0 66910.9375 0.383231887425314 -0.0937 -0.1277 2483 SpecPlus_000358 COP(=O)(OC)OC(Br)C(Cl)(Cl)Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B21 compound treatment 1180640.0 140000.0 0.69 1048000.0 -30600.0 -0.18 952920.0 26010.9375 0.148977447399043 0.3766 0.5197 1039256 SpecPlus_000359 COc1cc(cc(OC)c1OC)C(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B22 compound treatment 1262170.0 222000.0 1.08 1045440.0 -33200.0 -0.2 947320.0 20410.9375 0.116903489840433 0.5793 0.5229 2484 SpecPlus_000360 COP(=O)(OC)OC=C(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B23 mock treatment 1078240.0 37900.0 0.19 1018680.0 -59900.0 -0.36 1020850.0 93940.9375 0.538046007569816 0.2117 0.3153 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 B24 mock treatment 1036320.0 -4020.0 -0.02 954130.0 -124000.0 -0.74 933340.0 6430.9375 0.0368331457923338 -0.4175 -0.563 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C01 mock treatment 985930.0 -54400.0 -0.27 1053880.0 -24700.0 -0.15 805940.0 -120969.0625 -0.692849388666028 -0.6385 -0.8439 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C02 mock treatment 1001120.0 -39200.0 -0.19 1040360.0 -38300.0 -0.23 851600.0 -75309.0625 -0.431332084714938 -0.491 -0.9371 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C03 compound treatment 1102880.0 62500.0 0.31 1064390.0 -14200.0 -0.08 915400.0 -11509.0625 -0.0659180682436396 0.0895 0.2763 2060264 SpecPlus_000361 C[C@@H]1CC[C@]2(CCC3(C)[C@]4(OC2=O)C=CC5[C@@]6(C)CC[C@H](O)C(C)(C)C6CC[C@]53C)C4[C@H]1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C04 compound treatment 977340.0 -63000.0 -0.31 790310.0 -288000.0 -1.71 712340.0 -214569.0625 -1.2289426792885 -1.8771 -0.8805 2060265 SpecPlus_000362 COC(=O)CCC(C)[C@H]1CCC2C3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C05 compound treatment 920800.0 -120000.0 -0.58 883390.0 -195000.0 -1.16 791360.0 -135549.0625 -0.776356228166836 -1.4557 -0.9616 2060266 SpecPlus_000363 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC(=O)C4[C@@]5(C)CC[C@H](OC(=O)C)C(C)(C)C5CC[C@]43C)C2[C@H]1C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C06 compound treatment 1120320.0 80000.0 0.39 1164930.0 86300.0 0.51 1020130.0 93220.9375 0.533922213026566 0.8302 0.9914 2060267 SpecPlus_000364 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C07 compound treatment 1082400.0 42100.0 0.21 1047810.0 -30800.0 -0.18 958590.0 31680.9375 0.181452329427135 0.1176 0.3566 2060268 SpecPlus_000365 C[C@@H]1CC[C@]2(CCC3(C)[C@]4(OC2=O)C=CC5[C@@]6(C)CCC(=O)C(C)(C)C6CC[C@]53C)C4[C@H]1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C08 compound treatment 1079360.0 39000.0 0.19 1041600.0 -37000.0 -0.22 1081470.0 154560.9375 0.885246598141762 0.494 0.5301 2060269 SpecPlus_000366 C[C@H]1CN(C[C@@H](C)N1)c2c(F)c(F)c3c(=O)c(cn(C4CC4)c3c2F)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C09 compound treatment 775360.0 -265000.0 -1.29 90980.0 -988000.0 -5.87 577980.0 -348929.0625 -1.99848856099827 -5.2921 -0.8351 2060270 SpecPlus_000367 CC(C)c1ccc2c(CCC3C(C)(CCCC32C)C(=O)N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C10 compound treatment 136880.0 -903000.0 -4.41 116220.0 -962000.0 -5.72 126410.0 -800499.0625 -4.58485231363063 -8.4998 -0.9931 2060271 SpecPlus_000368 CCC(C)C(=O)c1c(O)c(C)c2oc3c(C)c(O)c(C(=O)C(C)CC)c(O)c3c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C11 compound treatment 1274320.0 234000.0 1.14 964700.0 -114000.0 -0.68 1053500.0 126590.9375 0.72504863512135 0.6875 0.4542 2060272 SpecPlus_000369 CC1CCC2C(CC2(C)C)C(=C)CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C12 compound treatment 945280.0 -95100.0 -0.46 836240.0 -242000.0 -1.44 894440.0 -32469.0625 -0.185966309391577 -1.2077 -0.7915 2060273 SpecPlus_000370 COc1cc2OCc3oc4cc(O)cc(O)c4c(=O)c3-c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C13 compound treatment 845920.0 -194000.0 -0.95 974660.0 -104000.0 -0.62 804040.0 -122869.0625 -0.70373162426627 -1.3117 -0.9832 2060274 SpecPlus_000371 CC(C)C1CC=C(C)C2CC(=O)C(=CC12)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C14 compound treatment 1314850.0 275000.0 1.34 1052750.0 -25900.0 -0.15 994040.0 67130.9375 0.384491935757974 0.9075 0.6465 3174366 SpecPlus_000372 C[C@H]1C2C(CC3C4CC[C@@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)OC(=O)C)O[C@]61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C15 compound treatment 1182340.0 142000.0 0.69 978450.0 -100000.0 -0.6 962370.0 35460.9375 0.203102250779196 0.1739 0.1856 2060275 SpecPlus_000373 CC(=CC[C@H](O)C1CCC(=CC1)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C16 compound treatment 1295100.0 255000.0 1.24 947440.0 -131000.0 -0.78 1009820.0 82910.9375 0.474871766164198 0.5424 0.3513 3174367 SpecPlus_000374 NCCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C17 compound treatment 990730.0 -49600.0 -0.24 834800.0 -244000.0 -1.45 870210.0 -56699.0625 -0.324743450756774 -1.1645 -0.7735 3053888 SpecPlus_000375 CC(=CCC[C@](C)(OC(=O)C)C1CCC(=CC1)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C18 compound treatment 1198430.0 158000.0 0.77 1001930.0 -76700.0 -0.46 1024160.0 97250.9375 0.557004007483922 0.5042 0.4775 2060276 SpecPlus_000376 C[C@@H]1C(=O)OC2[C@H](O)C34[C@@H]5OC(=O)[C@@]4(O[C@@H]6OC(=O)[C@H](O)[C@@]63[C@@H]([C@H]5O)C(C)(C)C)[C@@]12O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C19 compound treatment 942400.0 -97900.0 -0.48 791560.0 -287000.0 -1.71 815360.0 -111549.0625 -0.63889641005851 -1.6307 -0.8653 3053889 SpecPlus_000377 C[C@@H]1CC[C@H]2C(C)(C)C3CC12CC[C@@]3(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C20 compound treatment 1266100.0 226000.0 1.1 1000330.0 -78300.0 -0.47 1071840.0 144930.9375 0.830090846125796 0.8473 0.5816 3174369 SpecPlus_000378 C[C@H]1OC(C[C@H](O)C1O)O[C@@H]2[C@@H](C)OC(C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6C5CC[C@]7(C)[C@H]([C@@H](O)C[C@]67O)C8=CC(=O)OC8)C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C21 compound treatment 1109610.0 69300.0 0.34 1005810.0 -72800.0 -0.43 1162940.0 236030.9375 1.35186540569532 0.7259 0.4974 3053891 SpecPlus_000379 OC(=O)C/C(=C\C(=O)O)/C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C22 compound treatment 1080090.0 39800.0 0.19 1015430.0 -63200.0 -0.38 1084990.0 158080.9375 0.905407371464316 0.4179 0.4182 2880 SpecPlus_000380 N[C@@H](CCC(=O)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C23 mock treatment 1063710.0 23400.0 0.11 1144880.0 66300.0 0.39 958560.0 31650.9375 0.181280504654499 0.3981 0.8876 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 C24 mock treatment 993020.0 -47300.0 -0.23 957970.0 -121000.0 -0.72 964100.0 37190.9375 0.213010812667838 -0.4247 -0.5422 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D01 mock treatment 1020360.0 -20000.0 -0.1 1009250.0 -69400.0 -0.41 895640.0 -31269.0625 -0.179093318486161 -0.3979 -0.8647 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D02 mock treatment 1085210.0 44900.0 0.22 1085300.0 6670.0 0.04 905890.0 -21019.0625 -0.120386521169064 0.08 0.3158 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D03 compound treatment 772170.0 -268000.0 -1.31 783950.0 -295000.0 -1.75 683960.0 -242949.0625 -1.39148891420159 -2.5715 -0.9917 976 SpecPlus_000381 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D04 compound treatment 1039880.0 -458.0 0.0 1026940.0 -51700.0 -0.31 863970.0 -62939.0625 -0.360483003464939 -0.3869 -0.8166 2485 SpecPlus_000382 CCS(=O)CCSP(=O)(OC)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D05 compound treatment 1006440.0 -33900.0 -0.17 765130.0 -313000.0 -1.86 810590.0 -116319.0625 -0.66621654890754 -1.5566 -0.7835 2060277 SpecPlus_000383 COc1cccc2c(=O)c(OC)c(oc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D06 compound treatment 1246300.0 206000.0 1.01 974510.0 -104000.0 -0.62 931840.0 4930.9375 0.0282419071605634 0.2398 0.2029 2486 SpecPlus_000384 CNC(=O)CSP(=S)(OC)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D07 compound treatment 1041660.0 1320.0 0.01 1149360.0 70700.0 0.42 910470.0 -16439.0625 -0.0941546058800582 0.1922 0.4459 1727302 SpecPlus_000385 COc1ccc(cc1)c2coc3cc(OC)cc(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D08 compound treatment 1078000.0 37700.0 0.18 1003140.0 -75500.0 -0.45 1088820.0 161910.9375 0.927343667437436 0.3825 0.3655 2487 SpecPlus_000386 CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D09 compound treatment 802030.0 -238000.0 -1.16 823760.0 -255000.0 -1.52 758880.0 -168029.0625 -0.96238518200677 -2.1029 -0.9827 2060278 SpecPlus_000387 COC(=O)/C=C/C(=C/C=C/C(=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C(=O)O)/C)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D10 compound treatment 1112020.0 71700.0 0.35 932170.0 -146000.0 -0.87 1010250.0 83340.9375 0.477334587905305 -0.025 -0.0238 2488 SpecPlus_000388 CCOP(=S)(OCC)SCn1c(=O)oc2cc(Cl)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D11 compound treatment 1031200.0 -9140.0 -0.04 1046130.0 -32500.0 -0.19 888000.0 -38909.0625 -0.222851360583978 -0.266 -0.8917 2060279 SpecPlus_000389 CC(=O)OC1CC[C@@]2(C)C(CC[C@]3(C)C2CCC4C5CC(C)(C)CCC5(CC[C@]43C)C(=O)O)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D12 compound treatment 1202000.0 162000.0 0.79 985320.0 -93300.0 -0.55 1009540.0 82630.9375 0.473268068286267 0.4089 0.3804 2489 SpecPlus_000390 COP(=O)(N)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D13 compound treatment 731960.0 -308000.0 -1.51 810410.0 -268000.0 -1.59 637020.0 -289889.0625 -1.66033740845179 -2.7493 -0.9992 2269 SpecPlus_000391 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D14 compound treatment 891560.0 -149000.0 -0.73 783310.0 -295000.0 -1.76 767280.0 -159629.0625 -0.914274245668856 -1.9614 -0.93 2490 SpecPlus_000392 CCOP(=S)(OCC)SCSCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D15 compound treatment 1256750.0 216000.0 1.06 1002150.0 -76500.0 -0.45 1201280.0 274370.9375 1.57145746512337 1.2552 0.6444 2060280 SpecPlus_000393 C[C@H]1C2C(CC3C4CC[C@H]5C[C@H](CC[C@]5(C)C4CC[C@]23C)OC(=O)C)O[C@]61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D16 compound treatment 795960.0 -244000.0 -1.19 894520.0 -184000.0 -1.09 837370.0 -89539.0625 -0.512834301868333 -1.6175 -0.9519 2491 SpecPlus_000394 COC(=O)c1c(Cl)c(Cl)c(C(=O)OC)c(Cl)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D17 compound treatment 904040.0 -136000.0 -0.67 974560.0 -104000.0 -0.62 970040.0 43130.9375 0.247032117649648 -0.5991 -0.636 2060281 SpecPlus_000395 C[C@@]12CC[C@H](O)C[C@H]2CCc3ccccc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D18 compound treatment 913970.0 -126000.0 -0.62 889330.0 -189000.0 -1.13 880590.0 -46319.0625 -0.265292079424924 -1.1595 -0.8845 2492 SpecPlus_000396 CC(C)Nc1nc(Cl)nc(NC(C)C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D19 compound treatment 1370240.0 330000.0 1.61 1178970.0 100000.0 0.6 1150510.0 223600.9375 1.28067267490004 2.0145 0.9399 2060282 SpecPlus_000397 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D20 compound treatment 1072640.0 32300.0 0.16 995040.0 -83600.0 -0.5 1034880.0 107970.9375 0.618402726238975 0.1612 0.1992 2493 SpecPlus_000398 CCC(=O)Nc1ccc(Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D21 compound treatment 1217650.0 177000.0 0.87 980800.0 -97800.0 -0.58 1027150.0 100240.9375 0.574129209823251 0.4958 0.4163 2060283 SpecPlus_000399 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)C(=O)OC(=O)C=C43)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D22 compound treatment 1089070.0 48700.0 0.24 821600.0 -257000.0 -1.53 925810.0 -1099.0625 -0.0062948721391534 -0.7486 -0.4839 2494 SpecPlus_000400 CCNc1nc(Cl)nc(NCC)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D23 mock treatment 1088400.0 48100.0 0.23 1022160.0 -56500.0 -0.34 942300.0 15390.9375 0.0881514778861086 -0.0074 -0.0177 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 D24 mock treatment 994430.0 -45900.0 -0.22 1083680.0 5050.0 0.03 879430.0 -47479.0625 -0.271935970633493 -0.2692 -0.7608 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E01 mock treatment 1153870.0 114000.0 0.55 1132280.0 53700.0 0.32 909600.0 -17309.0625 -0.099137524286485 0.4472 0.6906 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E02 mock treatment 982770.0 -57600.0 -0.28 1122140.0 43500.0 0.26 1026030.0 99120.9375 0.567714418311529 0.3148 0.4599 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E03 compound treatment 892990.0 -147000.0 -0.72 1043010.0 -35600.0 -0.21 921210.0 -5699.0625 -0.0326413372765825 -0.5568 -0.7412 1014978 SpecPlus_000401 OCC(O)C(O)C(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E04 compound treatment 1108510.0 68200.0 0.33 1008890.0 -69700.0 -0.41 1003470.0 76560.9375 0.438502189289703 0.206 0.2989 2060284 SpecPlus_000402 COc1cc(OC)c(c(OC)c1)c2c(OC)cc(OC)cc2OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E05 compound treatment 971900.0 -68400.0 -0.33 926880.0 -152000.0 -0.9 884700.0 -42209.0625 -0.241752085573873 -0.8536 -0.8603 2060285 SpecPlus_000403 O=C1CCCCC/C=C/CCCCCCCCO1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E06 compound treatment 1007060.0 -33300.0 -0.16 1030790.0 -47800.0 -0.28 869570.0 -57339.0625 -0.32840904590633 -0.4477 -0.9651 2060286 SpecPlus_000404 CC(C)CC(=O)c1c(O)c(CC=C(C)C)c(O)c2c(cc(=O)oc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E07 compound treatment 52640.0 -988000.0 -4.83 46930.0 -1030000.0 -6.14 60170.0 -866739.0625 -4.96424141160961 -9.1943 -0.9939 2060287 SpecPlus_000405 Cc1c(O)c(O)cc2c1CC=C3[C@@]2(C)CC[C@@]4(C)C5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E08 compound treatment 935390.0 -105000.0 -0.51 753670.0 -325000.0 -1.93 700660.0 -226249.0625 -1.29583979076788 -2.1599 -0.9066 1010251 SpecPlus_000406 O=C(Nc1ccccc1)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E09 compound treatment 1124490.0 84200.0 0.41 1018500.0 -60100.0 -0.36 1011960.0 85050.9375 0.487128599945524 0.3122 0.4271 1045072 SpecPlus_000407 NC(CSCSCC(N)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E10 compound treatment 567630.0 -473000.0 -2.31 562120.0 -517000.0 -3.07 462510.0 -464399.0625 -2.65984211087196 -4.6424 -0.9933 2060288 SpecPlus_000408 Oc1ccc(cc1)C(=O)c2cccc(O)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E11 compound treatment 973670.0 -66700.0 -0.33 852530.0 -226000.0 -1.34 801360.0 -125549.0625 -0.719081303955033 -1.3795 -0.8848 3174484 SpecPlus_000409 C[C@@]12CCC3C(CC[C@H]4C[C@@H](O)CC[C@@]43C)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E12 compound treatment 523730.0 -517000.0 -2.52 496510.0 -582000.0 -3.46 658110.0 -268799.0625 -1.5395445932891 -4.3447 -0.9544 2060289 SpecPlus_000410 COc1cc2OCC3Oc4c5C=CC(C)(C)Oc5ccc4C(=O)C3c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E13 compound treatment 191680.0 -849000.0 -4.15 226410.0 -852000.0 -5.07 225850.0 -701059.0625 -4.01531046726847 -7.638 -0.9944 2060290 SpecPlus_000411 C[C@@H]1OC(O[C@H]2CC[C@@]3(C)C(CC[C@]4(C)C3CC=C5C6CC(C)(C)CC[C@@]6(C(O)C[C@]54C)C(=O)O[C@@H]7OC[C@H](O)[C@@H](O)[C@H]7OC8O[C@@H](C)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](O)[C@H]8O)C2(C)C)[C@H](O)[C@H](O)[C@H]1O[C@@H]%10OC[C@@H](O)[C@H](O)[C@H]%10O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E14 compound treatment 1255320.0 215000.0 1.05 1078420.0 -207.0 0.0 1036640.0 109730.9375 0.628483112900252 0.9686 0.7913 1009973 SpecPlus_000412 OC(C(O)C(O)C(=O)O)C(O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E15 compound treatment 1112660.0 72300.0 0.35 1034770.0 -43900.0 -0.26 998770.0 71860.9375 0.411582974910156 0.2911 0.4836 2060291 SpecPlus_000413 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)CC[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E16 compound treatment 1138810.0 98500.0 0.48 897700.0 -181000.0 -1.08 1012480.0 85570.9375 0.490106896004537 -0.0604 -0.0473 2060292 SpecPlus_000414 CC1(C)[C@H](O)C[C@H](O)[C@@]2(C)C1C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E17 compound treatment 918370.0 -122000.0 -0.6 910330.0 -168000.0 -1.0 871210.0 -55699.0625 -0.319015958335594 -1.106 -0.9158 2060293 SpecPlus_000415 C[C@@H]1CC[C@H]2C(C)(C)C3C[C@@]12CC[C@@]3(C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E18 compound treatment 386740.0 -654000.0 -3.19 418690.0 -660000.0 -3.92 360930.0 -565979.0625 -3.24164079101544 -5.981 -0.9954 2060294 SpecPlus_000416 COc1ccc2C(=O)C(Cc3ccc(OC)c(O)c3)COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E19 compound treatment 1129190.0 88900.0 0.43 1260390.0 182000.0 1.08 1100890.0 173980.9375 0.996474500961082 1.45 0.9459 3054072 SpecPlus_000417 OC(=O)CCCCCCCCCCCCC1CCC=C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E20 compound treatment 1072490.0 32200.0 0.16 1018240.0 -60400.0 -0.36 965060.0 38150.9375 0.218509205392171 0.0095 0.0212 1009993 SpecPlus_000418 NCCCN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E21 compound treatment 1335570.0 295000.0 1.44 1018560.0 -60100.0 -0.36 1069510.0 142600.9375 0.816745788784446 1.0981 0.6476 3054971 SpecPlus_000419 O[C@@H]1C[C@](O)(C[C@@H](O)[C@@H]1O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E22 compound treatment 1086140.0 45800.0 0.22 938720.0 -140000.0 -0.83 958890.0 31980.9375 0.183170577153489 -0.2454 -0.2786 3054972 SpecPlus_000420 CC(C)C1=CC2=CCC3[C@](C)(CCC[C@]3(C)C2CC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E23 mock treatment 1053050.0 12700.0 0.06 1017310.0 -61300.0 -0.36 1005660.0 78750.9375 0.451045397692088 0.0858 0.147 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 E24 mock treatment 1171250.0 131000.0 0.64 1184040.0 105000.0 0.63 976180.0 49270.9375 0.282198921115695 0.8941 0.9522 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F01 mock treatment 1008200.0 -32100.0 -0.16 1084910.0 6280.0 0.04 895420.0 -31489.0625 -0.180353366818821 -0.1732 -0.7157 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F02 mock treatment 1081610.0 41300.0 0.2 1100590.0 22000.0 0.13 876320.0 -50589.0625 -0.289748472063363 0.0245 0.0652 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F03 compound treatment 961490.0 -78800.0 -0.39 928350.0 -150000.0 -0.89 822560.0 -104349.0625 -0.597658464626012 -1.0834 -0.9487 2060295 SpecPlus_000421 CC(C)C1COc2cc3oc(=O)ccc3cc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F04 compound treatment 937320.0 -103000.0 -0.5 981310.0 -97300.0 -0.58 892320.0 -34589.0625 -0.198108593324479 -0.7391 -0.933 2495 SpecPlus_000422 CCNc1nc(Cl)nc(NC(C)C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F05 compound treatment 979360.0 -61000.0 -0.3 1037770.0 -40900.0 -0.24 871390.0 -55519.0625 -0.317985009699782 -0.4959 -0.9939 2060296 SpecPlus_000423 COc1ccc2CCC3CC(O)CC[C@]3(C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F06 compound treatment 1141660.0 101000.0 0.5 1099540.0 20900.0 0.12 921450.0 -5459.0625 -0.0312667390954992 0.3396 0.664 2496 SpecPlus_000424 CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F07 compound treatment 1017010.0 -23300.0 -0.11 905940.0 -173000.0 -1.03 902240.0 -24669.0625 -0.141291868506371 -0.7403 -0.7099 3054974 SpecPlus_000425 COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F08 compound treatment 994410.0 -45900.0 -0.22 1015360.0 -63300.0 -0.38 913020.0 -13889.0625 -0.0795495002060486 -0.3927 -0.882 2497 SpecPlus_000426 CNC(=O)N(C)c1nnc(s1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F09 compound treatment 1119690.0 79400.0 0.39 1085780.0 7150.0 0.04 874210.0 -52699.0625 -0.301833481072053 0.0741 0.1503 2060297 SpecPlus_000427 COc1cccc2c(C)cc(O)nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F10 compound treatment 1052400.0 12100.0 0.06 1030480.0 -48100.0 -0.29 860350.0 -66559.0625 -0.381216526029611 -0.3514 -0.7314 2498 SpecPlus_000428 COc1c(Cl)ccc(Cl)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F11 compound treatment 1025440.0 -14900.0 -0.07 1204050.0 125000.0 0.75 993920.0 67010.9375 0.383804636667432 0.6102 0.7247 2060298 SpecPlus_000429 CCCCCC1C(CC(=O)O)CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F12 compound treatment 1219440.0 179000.0 0.88 956290.0 -122000.0 -0.73 1050180.0 123270.9375 0.706033360283032 0.4928 0.368 2499 SpecPlus_000430 CCCCN(CC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F13 compound treatment 1291540.0 251000.0 1.23 963310.0 -115000.0 -0.69 992120.0 65210.9375 0.373495150309308 0.5283 0.3632 2060299 SpecPlus_000431 CC1(C)CC2/C(=C/C=C/C(C)(O)CCC21O)/CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F14 compound treatment 1065120.0 24800.0 0.12 1203430.0 125000.0 0.74 1050720.0 123810.9375 0.709126206190469 0.9078 0.8783 2500 SpecPlus_000432 COc1nc(NC(C)C)nc(NC(C)C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F15 compound treatment 584110.0 -456000.0 -2.23 535460.0 -543000.0 -3.23 476590.0 -450319.0625 -2.57919901758174 -4.6409 -0.9882 2060300 SpecPlus_000433 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O)c(c4cc(ccc4OC)c5cc(=O)c6c(O)cc(O)cc6o5)c3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F16 compound treatment 1055090.0 14800.0 0.07 943040.0 -136000.0 -0.81 1014050.0 87140.9375 0.49909905910579 -0.1357 -0.1427 2501 SpecPlus_000434 CCc1cccc(C)c1N(C(C)COC)C(=O)CCl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F17 compound treatment 721830.0 -319000.0 -1.56 664960.0 -414000.0 -2.46 678350.0 -248559.0625 -1.42362014668441 -3.1406 -0.9692 2060301 SpecPlus_000435 COc1ccc(cc1O)c2cc(=O)c3c(O)cc(O)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F18 compound treatment 1039300.0 -1040.0 -0.01 988480.0 -90100.0 -0.54 893920.0 -32989.0625 -0.188944605450591 -0.4215 -0.7416 2502 SpecPlus_000436 Clc1cccc(Cl)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F19 compound treatment 1114030.0 73700.0 0.36 1168850.0 90200.0 0.54 1046290.0 119380.9375 0.683753414764641 0.9124 0.9699 3054976 SpecPlus_000437 CC(C)[C@@H]1CC[C@@H](C)CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F20 compound treatment 957840.0 -82500.0 -0.4 943890.0 -135000.0 -0.8 875790.0 -51119.0625 -0.292784043046589 -0.8643 -0.9161 2503 SpecPlus_000438 CSc1nc(NC(C)C)nc(NC(C)C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F21 compound treatment 1357180.0 317000.0 1.55 1200440.0 122000.0 0.72 1137770.0 210860.9375 1.20770442145421 2.0092 0.9601 2060302 SpecPlus_000439 CC(C)CCC[C@@H](C)CCC[C@@H](C)CC/C(=C/CO)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F22 compound treatment 1227520.0 187000.0 0.91 1345920.0 267000.0 1.59 1023540.0 96630.9375 0.553452962182791 1.7652 0.9216 2504 SpecPlus_000440 CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F23 mock treatment 1018160.0 -22200.0 -0.11 1128960.0 50300.0 0.3 973710.0 46800.9375 0.26805201483538 0.265 0.6368 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 F24 mock treatment 1099480.0 59100.0 0.29 932430.0 -146000.0 -0.87 898410.0 -28499.0625 -0.163228164479492 -0.4293 -0.4614 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G01 mock treatment 995840.0 -44500.0 -0.22 1000400.0 -78200.0 -0.47 969490.0 42580.9375 0.243881996817999 -0.2533 -0.4456 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G02 mock treatment 1087870.0 47500.0 0.23 1185360.0 107000.0 0.63 971460.0 44550.9375 0.255165156887724 0.6478 0.8968 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G03 compound treatment 1099200.0 58900.0 0.29 1145020.0 66400.0 0.39 849980.0 -76929.0625 -0.44061062243725 0.1396 0.2122 2475 SpecPlus_000441 CC(=CC1C(C(=O)O)C1(C)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G04 compound treatment 994280.0 -46100.0 -0.23 1041280.0 -37300.0 -0.22 898180.0 -28729.0625 -0.164545487736363 -0.3531 -0.9908 2060303 SpecPlus_000442 Cc1occc(=O)c1/C=C/O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G05 compound treatment 1093980.0 53600.0 0.26 1136320.0 57700.0 0.34 935360.0 8450.9375 0.0484026804831178 0.3773 0.8686 1003823 SpecPlus_000443 Cc1occc(=O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G06 compound treatment 1028210.0 -12100.0 -0.06 1018760.0 -59900.0 -0.36 905300.0 -21609.0625 -0.12376574169756 -0.3112 -0.8157 2060304 SpecPlus_000444 OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G07 compound treatment 114940.0 -925000.0 -4.52 83130.0 -995000.0 -5.92 81520.0 -845389.0625 -4.84195944841741 -8.8237 -0.9932 3174490 SpecPlus_000445 COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5cc(O)c4C(=O)[C@H]3c2cc1OC)C(=C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G08 compound treatment 1069940.0 29600.0 0.14 1096970.0 18300.0 0.11 935470.0 8560.9375 0.0490327046494476 0.1748 0.9314 2060305 SpecPlus_000446 CCCCC[C@H](CC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G09 compound treatment 1096550.0 56200.0 0.27 1203580.0 125000.0 0.74 873090.0 -53819.0625 -0.308248272583775 0.4096 0.4819 2060306 SpecPlus_000447 C[C@@H](CCOC(=O)C)CCC=C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G10 compound treatment 931000.0 -109000.0 -0.53 961710.0 -117000.0 -0.7 872560.0 -54349.0625 -0.311283843567001 -0.8896 -0.9561 401 SpecPlus_000448 COc1cccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G11 compound treatment 1092220.0 51900.0 0.25 1141540.0 62900.0 0.37 1040160.0 113250.9375 0.648643886222806 0.7368 0.9321 2060307 SpecPlus_000449 COc1ccc2[C@@H](O)[C@H](Cc3ccc(OC)c(OC)c3)COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G12 compound treatment 1069860.0 29500.0 0.14 1152010.0 73400.0 0.44 1058460.0 131550.9375 0.753456997530404 0.7702 0.8727 2060308 SpecPlus_000450 C/C(=C/C(=O)O)/C=C/C1(O)C(=CC(=O)CC1(C)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G13 compound treatment 1079730.0 39400.0 0.19 1079720.0 1090.0 0.01 1006430.0 79520.9375 0.455455566856397 0.3778 0.7641 3174492 SpecPlus_000451 CN1[C@H]2CC3CC1C(O)C2O3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G14 compound treatment 611850.0 -428000.0 -2.09 748290.0 -330000.0 -1.96 524960.0 -401949.0625 -2.30216020916925 -3.672 -0.9979 1043296 SpecPlus_000452 Cc1nccc2c3ccc(O)cc3[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G15 compound treatment 988980.0 -51400.0 -0.25 841120.0 -238000.0 -1.41 798510.0 -128399.0625 -0.735404657355397 -1.3849 -0.8591 1052459 SpecPlus_000453 COc1c2ccoc2cc3oc(C)cc(=O)c13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G16 compound treatment 1530200.0 490000.0 2.39 1220190.0 142000.0 0.84 1170350.0 243440.9375 1.39430612453626 2.6728 0.9233 3054980 SpecPlus_000454 Nc1ncnc2n(cnc12)C3C[C@H](O)[C@@H](CO)O3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G17 compound treatment 1137030.0 96700.0 0.47 997680.0 -80900.0 -0.48 976260.0 49350.9375 0.282657120509389 0.158 0.2161 3174493 SpecPlus_000455 N[C@H]([C@@H](O)[C@H](O)[C@H](O)CO)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G18 compound treatment 1110920.0 70600.0 0.34 1135040.0 56400.0 0.34 943700.0 16790.9375 0.096169967275761 0.4483 0.9138 2060309 SpecPlus_000456 CC12CCC3C(CCC4(O)CC(O)CCC34/C=N/NC(=O)N)C2(O)CCC1C5=CC(=O)OC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G19 compound treatment 1042080.0 1740.0 0.01 956130.0 -122000.0 -0.73 691400.0 -235509.0625 -1.34887637058801 -1.1944 -0.7791 1003215 SpecPlus_000457 CC(C)C1=CC(=O)C(=CC1=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G20 compound treatment 997530.0 -42800.0 -0.21 978090.0 -101000.0 -0.6 950310.0 23400.9375 0.134028692179762 -0.3885 -0.6002 3054981 SpecPlus_000458 COc1ccc(cc1)c2cc(=O)c3c(OC(=O)C)cc(OC(=O)C)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G21 compound treatment 795380.0 -245000.0 -1.2 777720.0 -301000.0 -1.79 686570.0 -240339.0625 -1.37654015898231 -2.5188 -0.9858 2060310 SpecPlus_000459 CC(C)C1=CC2=CC[C@H]3[C@](C)(CO)CCC[C@]3(C)C2CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G22 compound treatment 624290.0 -416000.0 -2.03 595790.0 -483000.0 -2.87 515700.0 -411209.0625 -2.35519678898938 -4.1911 -0.99 1113841 SpecPlus_000460 Oc1ccc2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G23 mock treatment 1131520.0 91200.0 0.45 1063850.0 -14800.0 -0.09 947330.0 20420.9375 0.116960764764645 0.274 0.5843 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 G24 mock treatment 1173030.0 133000.0 0.65 1126720.0 48100.0 0.29 993820.0 66910.9375 0.383231887425314 0.7607 0.9443 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H01 mock treatment 1149630.0 109000.0 0.53 1073120.0 -5510.0 -0.03 864710.0 -62199.0625 -0.356244659073266 0.0837 0.1302 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H02 mock treatment 1154080.0 114000.0 0.56 1155390.0 76800.0 0.46 962810.0 35900.9375 0.205622347444515 0.7031 0.94 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H03 compound treatment 1200100.0 160000.0 0.78 1171230.0 92600.0 0.55 1210400.0 283490.9375 1.62369219600453 1.706 0.9056 3174602 SpecPlus_000461 O=c1[nH]cnc2nc[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H04 compound treatment 1027040.0 -13300.0 -0.06 1142310.0 63700.0 0.38 851680.0 -75229.0625 -0.430873885321244 -0.0676 -0.1172 2505 SpecPlus_000462 CC(C)N1C(=O)c2ccccc2NS1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H05 compound treatment 486530.0 -554000.0 -2.71 505760.0 -573000.0 -3.41 373440.0 -553469.0625 -3.16998986082648 -5.3592 -0.9956 1016582 SpecPlus_000463 COc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H06 compound treatment 1049870.0 9530.0 0.05 1071050.0 -7580.0 -0.05 792890.0 -134019.0625 -0.76759316476243 -0.4423 -0.5742 2506 SpecPlus_000464 OC(=O)COc1ccc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H07 compound treatment 1070770.0 30400.0 0.15 1355520.0 277000.0 1.65 853920.0 -72989.0625 -0.4180443022978 0.7951 0.4663 2060311 SpecPlus_000465 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4CC(=O)CC[C@]4(C)C3C=C[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H08 compound treatment 1061540.0 21200.0 0.1 1122630.0 44000.0 0.26 825890.0 -101019.0625 -0.578585914863482 -0.1232 -0.1914 2507 SpecPlus_000466 OC(=O)CCCOc1ccc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H09 compound treatment 1258980.0 219000.0 1.07 1108490.0 29900.0 0.18 1021520.0 94610.9375 0.541883427492007 1.0321 0.8524 2060312 SpecPlus_000467 NC(Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H10 compound treatment 1046130.0 5790.0 0.03 963890.0 -115000.0 -0.68 847000.0 -79909.0625 -0.457678549852368 -0.6418 -0.7807 2508 SpecPlus_000468 OC(=O)COc1cc(Cl)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H11 compound treatment 1152640.0 112000.0 0.55 1191170.0 113000.0 0.67 893810.0 -33099.0625 -0.189574629616921 0.5937 0.6702 2060313 SpecPlus_000469 C/C/1=C/CC(C)(C)\C=C\C\C(=C\CC1)\C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H12 compound treatment 855200.0 -185000.0 -0.9 967800.0 -111000.0 -0.66 850520.0 -76389.0625 -0.437517776529813 -1.1553 -0.9615 2509 SpecPlus_000470 CCc1cccc(CC)c1N(COC)C(=O)CCl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H13 compound treatment 1214110.0 174000.0 0.85 1016910.0 -61700.0 -0.37 922400.0 -4509.0625 -0.025825621295378 0.2634 0.2846 1090658 SpecPlus_000471 COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H14 compound treatment 981190.0 -59100.0 -0.29 1305320.0 227000.0 1.35 923250.0 -3659.0625 -0.0209572527373748 0.5993 0.4347 2510 SpecPlus_000472 COC(=O)COc1ccc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H15 compound treatment 985800.0 -54500.0 -0.27 932320.0 -146000.0 -0.87 909340.0 -17569.0625 -0.100626672315992 -0.7142 -0.7802 3419385 SpecPlus_000473 CC12CC=C3C(CCC4=CC(=O)C=CC43C)C2CCC1C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H16 compound treatment 978940.0 -61400.0 -0.3 867060.0 -212000.0 -1.26 941050.0 14140.9375 0.0809921123596333 -0.8528 -0.6581 2511 SpecPlus_000474 COC(=O)CCCOc1ccc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H17 compound treatment 1011680.0 -28700.0 -0.14 989870.0 -88800.0 -0.53 921370.0 -5539.0625 -0.0317249384891936 -0.4039 -0.7384 2572 SpecPlus_000475 COc1cc2CC[N+](C)(C)[C@@H]3Cc4ccc(O)c(Oc5cc6[C@H](Cc7ccc(Oc(c1O)c32)cc7)N(C)CCc6cc5OC)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H18 compound treatment 918310.0 -122000.0 -0.6 940370.0 -138000.0 -0.82 866030.0 -60879.0625 -0.348684369077308 -1.0202 -0.9501 2512 SpecPlus_000476 COC(=O)COc1cc(Cl)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H19 compound treatment 730730.0 -310000.0 -1.51 723040.0 -356000.0 -2.11 634190.0 -292719.0625 -1.67654621200373 -3.0621 -0.9898 1119359 SpecPlus_000477 COc1cc2ccc(=O)oc2c(O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H20 compound treatment 1209790.0 169000.0 0.83 1204730.0 126000.0 0.75 941610.0 14700.9375 0.0841995081154943 0.9596 0.8566 2513 SpecPlus_000478 OC(=O)CNCP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H21 compound treatment 1159940.0 120000.0 0.58 1111280.0 32700.0 0.19 1035130.0 108220.9375 0.61983459934427 0.8073 0.924 2060314 SpecPlus_000479 COC(=O)c1c(C)c2Oc3c(Cl)c(OC)c(Cl)c(C)c3C(=O)Oc2c(C)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H22 compound treatment 1137440.0 97100.0 0.47 1072220.0 -6410.0 -0.04 1106780.0 179870.9375 1.03020943132183 0.8467 0.7461 2514 SpecPlus_000480 CCCCCCC(C)OC(=O)COc1ccc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H23 mock treatment 1099910.0 59600.0 0.29 1122750.0 44100.0 0.26 963680.0 36770.9375 0.210605265850942 0.4411 0.9916 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 H24 mock treatment 1071090.0 30800.0 0.15 1060050.0 -18600.0 -0.11 974770.0 47860.9375 0.274123156801831 0.1812 0.5466 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I01 mock treatment 986410.0 -53900.0 -0.26 954160.0 -124000.0 -0.74 851610.0 -75299.0625 -0.431274809790727 -0.8284 -0.9244 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I02 mock treatment 1056710.0 16400.0 0.08 1144500.0 65900.0 0.39 988280.0 61370.9375 0.351501579411976 0.4753 0.8928 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I03 compound treatment 849840.0 -190000.0 -0.93 907140.0 -171000.0 -1.02 733680.0 -193229.0625 -1.10671799102051 -1.7651 -0.9975 3174607 SpecPlus_000481 CC[C@@H]1[C@@H](OC(=O)C)N2[C@H]3C[C@@]45C(OC(=O)C)C3[C@@H]1CC2[C@@H]5N(C)c6ccccc64 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I04 compound treatment 1223840.0 184000.0 0.9 1195290.0 117000.0 0.69 854140.0 -72769.0625 -0.416784253965141 0.6775 0.561 1010348 SpecPlus_000482 OC1=CC(=O)c2ccccc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I05 compound treatment 890180.0 -150000.0 -0.73 966990.0 -112000.0 -0.66 818930.0 -107979.0625 -0.618449262114897 -1.1639 -0.9975 2060046 SpecPlus_000483 C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)[C@@]4(C)O[C@]43[C@H]2OC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I06 compound treatment 591250.0 -449000.0 -2.19 608430.0 -470000.0 -2.8 517060.0 -409849.0625 -2.34740739929657 -4.2364 -0.9946 1009367 SpecPlus_000484 OC1=CC2=C3c4ccc(O)c(O)c4OCC3(O)CC2=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I07 compound treatment 1023560.0 -16800.0 -0.08 896060.0 -183000.0 -1.09 929800.0 2890.9375 0.0165578226213557 -0.6646 -0.6103 1003115 SpecPlus_000485 COc1cc(cc(OC)c1O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I08 compound treatment 975930.0 -64400.0 -0.31 1126480.0 47900.0 0.28 839710.0 -87199.0625 -0.499431969602771 -0.3057 -0.4666 2060315 SpecPlus_000486 C[N+]1(C)C[C@H](O)[C@@H](C1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I09 compound treatment 792520.0 -248000.0 -1.21 849600.0 -229000.0 -1.36 755040.0 -171869.0625 -0.984378752904102 -2.0537 -0.9915 2060316 SpecPlus_000487 COc1c2C=CC(C)(C)Oc2cc3occ(c4ccc5OCOc5c4)c(=O)c13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I10 compound treatment 990920.0 -49400.0 -0.24 1040960.0 -37700.0 -0.22 961690.0 34780.9375 0.199207555932793 -0.1537 -0.3993 1002002 SpecPlus_000488 O[C@@H]1CC(=C[C@@H](O)[C@H]1O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I11 compound treatment 961930.0 -78400.0 -0.38 984680.0 -93900.0 -0.56 851680.0 -75229.0625 -0.430873885321244 -0.7925 -0.9871 2060317 SpecPlus_000489 COc1cc(OC)c2c(OC)c(c3ccc4OCOc4c3)c(=O)oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I12 compound treatment 983010.0 -57300.0 -0.28 1087650.0 9020.0 0.05 837320.0 -89589.0625 -0.513120676489392 -0.427 -0.7273 1024984 SpecPlus_000490 COc1cc2cccc(OC)c(=O)c2c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I13 compound treatment 959330.0 -81000.0 -0.4 1088570.0 9940.0 0.06 950940.0 24030.9375 0.137637012405106 -0.1149 -0.2715 1065857 SpecPlus_000491 NC(CNC(=O)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I14 compound treatment 1059230.0 18900.0 0.09 1219810.0 141000.0 0.84 944560.0 17650.9375 0.101095610757976 0.5964 0.7011 3174608 SpecPlus_000492 COC1C(O)C(O)C(O)[C@@H](O)C1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I15 compound treatment 620210.0 -420000.0 -2.05 603930.0 -475000.0 -2.82 449500.0 -477409.0625 -2.73435678727151 -4.3935 -0.9909 1651081 SpecPlus_000493 COc1cc(O)c2c(=O)c(coc2c1)c3ccc(O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I16 compound treatment 1135390.0 95100.0 0.46 1041640.0 -37000.0 -0.22 824710.0 -102199.0625 -0.585344355920475 -0.1968 -0.2527 3174609 SpecPlus_000494 CC(C)c1c(C(=O)c2ccccc2)c(c(c3ccc(F)cc3)n1CC[C@@H](O)C[C@@H](O)CC(=O)O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I17 compound treatment 916930.0 -123000.0 -0.6 951840.0 -127000.0 -0.75 864330.0 -62579.0625 -0.358421106193314 -0.9903 -0.9617 1011559 SpecPlus_000495 Cc1cc(=O)oc2cc(O)c(O)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I18 compound treatment 1006530.0 -33800.0 -0.17 1015360.0 -63300.0 -0.38 1081860.0 154950.9375 0.887480320186022 0.1998 0.2043 3174610 SpecPlus_000496 COc1cc(cc(OC)c1OC)C(=O)O[C@H]2CC[C@@]3(C)[C@@H]4CC[C@@H]5[C@@]3(C[C@@]6(O)[C@@H]7CN8C[C@@H](C)CC[C@H]8[C@@](C)(O)[C@@]7(O)[C@@H](O)C[C@@]56O)O[C@@]42O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I19 compound treatment 445010.0 -595000.0 -2.91 489660.0 -589000.0 -3.5 439290.0 -487619.0625 -2.79283448489176 -5.3138 -0.9949 1030891 SpecPlus_000497 Cc1cc(=O)oc2c(O)c(O)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I20 compound treatment 780750.0 -260000.0 -1.27 918780.0 -160000.0 -0.95 699360.0 -227549.0625 -1.30328553091542 -2.0335 -0.991 2060318 SpecPlus_000498 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@]12O[C@]2(C)C[C@@H](O)CC1(C)C)/C=C/C=C(\C)/C=C/C3=C(C)C[C@@H](O)CC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I21 compound treatment 864650.0 -176000.0 -0.86 897680.0 -181000.0 -1.08 715840.0 -211069.0625 -1.20889645581437 -1.8148 -0.9906 2060319 SpecPlus_000499 COc1ccc(cc1)c2oc3ccccc3c(=O)c2OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I22 compound treatment 1160800.0 120000.0 0.59 1134310.0 55700.0 0.33 924330.0 -2579.0625 -0.0147715609225001 0.5224 0.7735 839435 SpecPlus_000500 NCCCCNC(=N)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I23 mock treatment 1017770.0 -22600.0 -0.11 1294350.0 216000.0 1.28 905070.0 -21839.0625 -0.125083064954431 0.6048 0.4675 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 I24 mock treatment 980000.0 -60300.0 -0.29 1064200.0 -14400.0 -0.09 918120.0 -8789.0625 -0.0503392888580294 -0.2488 -0.7997 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J01 mock treatment 1163380.0 123000.0 0.6 1092510.0 13900.0 0.08 927540.0 630.9375 0.0036136897494884 0.3968 0.654 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J02 mock treatment 1039210.0 -1130.0 -0.01 1097150.0 18500.0 0.11 964900.0 37990.9375 0.217592806604782 0.186 0.7626 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J03 compound treatment 230730.0 -810000.0 -3.96 280110.0 -799000.0 -4.75 123570.0 -803339.0625 -4.60111839210678 -7.6817 -0.997 854065 SpecPlus_000501 CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J04 compound treatment 1091800.0 51500.0 0.25 1236240.0 158000.0 0.94 891370.0 -35539.0625 -0.203549711124601 0.5688 0.5736 2515 SpecPlus_000502 CCCCCCC(C)OC(=O)COc1cc(Cl)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J05 compound treatment 1013600.0 -26700.0 -0.13 1059520.0 -19100.0 -0.11 769760.0 -157149.0625 -0.900070064464329 -0.6607 -0.7208 2060320 SpecPlus_000503 COc1ccc2CC[C@@H]3CC(=O)CC[C@]3(C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J06 compound treatment 1011490.0 -28800.0 -0.14 1040710.0 -37900.0 -0.23 762740.0 -164169.0625 -0.940277061261014 -0.7544 -0.7721 2516 SpecPlus_000504 CC(C)OC(=O)Nc1cccc(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J07 compound treatment 879140.0 -161000.0 -0.79 1022880.0 -55700.0 -0.33 759800.0 -167109.0625 -0.957115888979284 -1.1987 -0.9342 2060321 SpecPlus_000505 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4c(=O)cc(oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J08 compound treatment 35070.0 -1010000.0 -4.91 43130.0 -1040000.0 -6.16 41120.0 -885789.0625 -5.07335014223309 -9.3199 -0.9948 2517 SpecPlus_000506 CC(C)N(C(=O)CCl)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J09 compound treatment 745500.0 -295000.0 -1.44 906780.0 -172000.0 -1.02 754340.0 -172569.0625 -0.988387997598928 -1.9923 -0.9844 2060322 SpecPlus_000507 COc1ccc2c(=O)c(OC)c(oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J10 compound treatment 1014500.0 -25800.0 -0.13 981030.0 -97600.0 -0.58 818310.0 -108599.0625 -0.622000307416028 -0.7671 -0.8919 2518 SpecPlus_000508 CCCCSP(=O)(SCCCC)SCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J11 compound treatment 1090210.0 49900.0 0.24 1068960.0 -9670.0 -0.06 766440.0 -160469.0625 -0.919085339302647 -0.4231 -0.4442 2060323 SpecPlus_000509 COc1ccccc1c2cc(=O)c3c(OC)cccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J12 compound treatment 853810.0 -187000.0 -0.91 1060210.0 -18400.0 -0.11 782260.0 -144649.0625 -0.828476409199576 -1.0677 -0.8635 2519 SpecPlus_000510 CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J13 compound treatment 950970.0 -89400.0 -0.44 1062430.0 -16200.0 -0.1 1013760.0 86850.9375 0.497438086303648 -0.0205 -0.0307 2060324 SpecPlus_000511 CC12CC[C@@H]3[C@H](CC3(C)C)C(=C)CC2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J14 compound treatment 1294790.0 254000.0 1.24 1390500.0 312000.0 1.85 951930.0 25020.9375 0.143307229902074 1.8712 0.8364 2520 SpecPlus_000512 Clc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J15 compound treatment 1196230.0 156000.0 0.76 1149130.0 70500.0 0.42 1067840.0 140930.9375 0.807180876441075 1.1478 0.9675 3174614 SpecPlus_000513 CC(C)CCCC(C)C1CCC2C3CC=C4C[C@@H](O)CCC4(C)C3CCC12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J16 compound treatment 1076050.0 35700.0 0.17 1022980.0 -55600.0 -0.33 871560.0 -55349.0625 -0.317011335988181 -0.2733 -0.5574 2521 SpecPlus_000514 Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J17 compound treatment 1218200.0 178000.0 0.87 1285320.0 207000.0 1.23 1019270.0 92360.9375 0.528996569544351 1.5168 0.9506 3174615 SpecPlus_000515 CC(C)CCCC(C)[C@H]1CCC2C3CC=C4CC(=O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J18 compound treatment 1005280.0 -35100.0 -0.17 1063470.0 -15200.0 -0.09 809600.0 -117309.0625 -0.671886766404508 -0.5388 -0.7706 2522 SpecPlus_000516 CNC(=O)Oc1cccc2CC(C)(C)Oc21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J19 compound treatment 1098190.0 57900.0 0.28 1129440.0 50800.0 0.3 1054810.0 127900.9375 0.732551650193097 0.7606 0.904 2060325 SpecPlus_000517 COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(c34)-c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J20 compound treatment 878310.0 -162000.0 -0.79 793190.0 -285000.0 -1.7 674970.0 -251939.0625 -1.442979071068 -2.2701 -0.9602 2523 SpecPlus_000518 CCOP(=S)(OCC)Oc1nc(Cl)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J21 compound treatment 856960.0 -183000.0 -0.9 869670.0 -209000.0 -1.24 718680.0 -208229.0625 -1.19263037733822 -1.9232 -0.9906 1737132 SpecPlus_000519 COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c2c34)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J22 compound treatment 766170.0 -274000.0 -1.34 804480.0 -274000.0 -1.63 710610.0 -216299.0625 -1.23885124117714 -2.4298 -0.9931 2524 SpecPlus_000520 COP(=O)(NC(=O)C)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J23 mock treatment 1145390.0 105000.0 0.51 1180090.0 101000.0 0.6 966840.0 39930.9375 0.228704141901872 0.7767 0.9421 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 J24 mock treatment 1086370.0 46000.0 0.22 1144900.0 66300.0 0.39 937380.0 10470.9375 0.0599722151739019 0.392 0.8565 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K01 mock treatment 1071420.0 31100.0 0.15 1113710.0 35100.0 0.21 940060.0 13150.9375 0.0753218948626649 0.2516 0.936 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K02 mock treatment 969960.0 -70400.0 -0.34 1132370.0 53700.0 0.32 906820.0 -20089.0625 -0.115059953217366 -0.0804 -0.1664 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K03 compound treatment 974680.0 -65700.0 -0.32 1164320.0 85700.0 0.51 870670.0 -56239.0625 -0.322108804243031 -0.077 -0.1127 1499608 SpecPlus_000521 COc1ccc2c(=O)cc(oc2c1)c3ccccc3OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K04 compound treatment 1020750.0 -19600.0 -0.1 1154430.0 75800.0 0.45 912260.0 -14649.0625 -0.0839023944461455 0.1566 0.3342 2060326 SpecPlus_000522 CC(=C)C1CC[C@@](C)(O)C2CC3OC3(C)C2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K05 compound treatment 1010450.0 -29900.0 -0.15 1227210.0 149000.0 0.88 922190.0 -4719.0625 -0.0270283947038258 0.4102 0.4578 1031375 SpecPlus_000523 NC(CCCNC(=O)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K06 compound treatment 208330.0 -832000.0 -4.07 208600.0 -870000.0 -5.17 187600.0 -739309.0625 -4.23438705237861 -7.7787 -0.9942 2060327 SpecPlus_000524 COc1cc2CCN(C)[C@H]3Oc4ccc(O)c(Oc5cc6[C@H](Cc7ccc(Oc(c1O)c32)cc7)N(C)CCc6cc5OC)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K07 compound treatment 346270.0 -694000.0 -3.39 400320.0 -678000.0 -4.03 328700.0 -598209.0625 -3.42623787175008 -6.2648 -0.9967 2060328 SpecPlus_000525 CC(C)CC(=O)c1c(O)c(C)c(O)c2c1oc3c(C(=O)CC(C)C)c(O)c(C)c(O)c32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K08 compound treatment 796120.0 -244000.0 -1.19 803650.0 -275000.0 -1.64 597950.0 -328959.0625 -1.8841105373473 -2.7208 -0.9839 3172723 SpecPlus_000526 CC(=O)OC[C@@]1(O)C[C@@]2(C[C@H]1CCC23)CCC4c5ccoc5CC[C@@]43C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K09 compound treatment 743040.0 -297000.0 -1.45 955890.0 -123000.0 -0.73 686200.0 -240709.0625 -1.37865933117815 -2.056 -0.9646 1001933 SpecPlus_000527 CNC(=O)Oc1ccc2N(C)C3N(C)CCC3(C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K10 compound treatment 698100.0 -342000.0 -1.67 730560.0 -348000.0 -2.07 648740.0 -278169.0625 -1.59321119727556 -3.0802 -0.9932 1978 SpecPlus_000528 OC(=O)/C=C/c1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K11 compound treatment 41060.0 -999000.0 -4.88 41780.0 -1040000.0 -6.17 47520.0 -879389.0625 -5.03669419073754 -9.2865 -0.9944 2060329 SpecPlus_000529 CCOc1ccc(cc1)c2cc(=O)c3c(OCC)cc(OCC)c(c4cc(ccc4OC)c5cc(=O)c6c(OCC)cc(OC)cc6o5)c3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K12 compound treatment 1119170.0 78800.0 0.39 1112260.0 33600.0 0.2 869350.0 -57559.0625 -0.329669094238989 0.1475 0.2707 2060330 SpecPlus_000530 OC[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K13 compound treatment 645670.0 -395000.0 -1.93 721150.0 -357000.0 -2.13 570170.0 -356739.0625 -2.04322027680769 -3.5203 -0.9992 2181 SpecPlus_000531 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3cc(O)c(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K14 compound treatment 819560.0 -221000.0 -1.08 953470.0 -125000.0 -0.74 846030.0 -80879.0625 -0.463234217500912 -1.3199 -0.9496 2554 SpecPlus_000532 C[C@H]1[C@H]2CCC3C4CC=C5C[C@H](CC[C@]5(C)C4CC[C@]23CN1C)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K15 compound treatment 922000.0 -118000.0 -0.58 1008700.0 -69900.0 -0.42 858160.0 -68749.0625 -0.393759734431996 -0.8012 -0.9846 2060331 SpecPlus_000533 CC1=CCC(=C)[C@H]2CC(C)(C)[C@@H]2CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K16 compound treatment 817700.0 -223000.0 -1.09 835360.0 -243000.0 -1.45 729280.0 -197629.0625 -1.1319189576737 -2.1167 -0.9916 2060332 SpecPlus_000534 OC/C=C/c1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K17 compound treatment 1662640.0 622000.0 3.04 1643730.0 565000.0 3.36 1421390.0 494480.9375 2.83213582194935 5.3307 0.9975 1013195 SpecPlus_000535 Nc1ncnc2[nH]cnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K18 compound treatment 1040480.0 142.0 0.0 1160440.0 81800.0 0.49 891200.0 -35709.0625 -0.204523384836201 0.1632 0.3092 3055245 SpecPlus_000536 CCC[C@@H]1CCCCN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K19 compound treatment 39160.0 -1000000.0 -4.89 42990.0 -1040000.0 -6.16 41300.0 -885609.0625 -5.07231919359728 -9.3083 -0.9946 3172726 SpecPlus_000537 C[C@]12C3CCC(O3)[C@]2(C)C(=O)OC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K20 compound treatment 460510.0 -580000.0 -2.83 437060.0 -642000.0 -3.82 337070.0 -589839.0625 -3.3782987601848 -5.7887 -0.9929 3055248 SpecPlus_000538 C=CC(C1=CC(=O)C=CC1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K21 compound treatment 1089560.0 49200.0 0.24 1153920.0 75300.0 0.45 904520.0 -22389.0625 -0.128233185786081 0.3233 0.6168 3172727 SpecPlus_000539 CC(=C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K22 compound treatment 1075520.0 35200.0 0.17 1149760.0 71100.0 0.42 897980.0 -28929.0625 -0.165690986220599 0.2478 0.5102 2060333 SpecPlus_000540 COc1ccc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K23 mock treatment 1033290.0 -7050.0 -0.03 1078720.0 92.9 0.0 917120.0 -9789.0625 -0.0560667812792096 -0.0519 -0.7893 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 K24 mock treatment 1016550.0 -23800.0 -0.12 1261790.0 183000.0 1.09 935680.0 8770.9375 0.0502354780578955 0.5907 0.5387 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L01 mock treatment 1062980.0 22600.0 0.11 1079900.0 1270.0 0.01 846650.0 -80259.0625 -0.459683172199781 -0.1972 -0.4169 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L02 mock treatment 973120.0 -67200.0 -0.33 1075520.0 -3110.0 -0.02 879770.0 -47139.0625 -0.269988623210291 -0.3562 -0.8369 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L03 compound treatment 1059450.0 19100.0 0.09 1216320.0 138000.0 0.82 879230.0 -47679.0625 -0.273081469117729 0.369 0.425 4895 SpecPlus_000541 C[n+]1cccc(c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L04 compound treatment 1000130.0 -40200.0 -0.2 1144090.0 65500.0 0.39 836800.0 -90109.0625 -0.516098972548406 -0.1866 -0.2762 3172728 SpecPlus_000542 CNC(=O)O/N=C(/C)\SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L05 compound treatment 1036810.0 -3530.0 -0.02 1230660.0 152000.0 0.9 865130.0 -61779.0625 -0.35383911225637 0.3077 0.3169 2060334 SpecPlus_000543 C[C@H]1[C@@H](O)C[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L06 compound treatment 975860.0 -64500.0 -0.32 1032800.0 -45800.0 -0.27 877330.0 -49579.0625 -0.283963704717971 -0.5032 -0.9981 3055253 SpecPlus_000544 CNC(=O)O/N=C/C(C)(C)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L07 compound treatment 677970.0 -362000.0 -1.77 666120.0 -413000.0 -2.45 717120.0 -209789.0625 -1.20156526551526 -3.1321 -0.9622 1275107 SpecPlus_000545 C1Cc2c(CN1)[nH]c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L08 compound treatment 1013050.0 -27300.0 -0.13 1209990.0 131000.0 0.78 891680.0 -35229.0625 -0.201774188474035 0.2575 0.3149 2527 SpecPlus_000546 COP(=S)(OC)Oc1ccc(Sc2ccc(OP(=S)(OC)OC)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L09 compound treatment 921050.0 -119000.0 -0.58 1070950.0 -7680.0 -0.05 844440.0 -82469.0625 -0.472340930450589 -0.6356 -0.8456 802058 SpecPlus_000547 COc1cc(/C=C/C(=O)O)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L10 compound treatment 894760.0 -146000.0 -0.71 954460.0 -124000.0 -0.74 853470.0 -73439.0625 -0.420621673887331 -1.0798 -0.9744 2528 SpecPlus_000548 CNC(=O)Oc1cccc2OC(C)(C)Oc21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L11 compound treatment 816700.0 -224000.0 -1.09 944000.0 -135000.0 -0.8 791860.0 -135049.0625 -0.773492481956246 -1.5396 -0.987 2081691 SpecPlus_000549 CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L12 compound treatment 848510.0 -192000.0 -0.94 916540.0 -162000.0 -0.96 740800.0 -186109.0625 -1.06593824498171 -1.713 -0.9984 2529 SpecPlus_000550 COP(=S)(OC)Oc1ccc(SC)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L13 compound treatment 136050.0 -904000.0 -4.42 151920.0 -927000.0 -5.51 138890.0 -788019.0625 -4.5133732082143 -8.3383 -0.9948 3172730 SpecPlus_000551 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccco4)ncnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L14 compound treatment 946910.0 -93400.0 -0.46 1073850.0 -4780.0 -0.03 867720.0 -59189.0625 -0.339004906885513 -0.4757 -0.8355 2530 SpecPlus_000552 CCCSP(=O)(OCC)SCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L15 compound treatment 1035060.0 -5280.0 -0.03 1032480.0 -46100.0 -0.27 855810.0 -71099.0625 -0.40721934162177 -0.4084 -0.8306 907179 SpecPlus_000553 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)C(O)CC1(C)C)/C=C/C=C(\C)/C=C/C2=C(C)C(=O)C(O)CC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L16 compound treatment 875050.0 -165000.0 -0.81 920820.0 -158000.0 -0.94 753650.0 -173259.0625 -0.992339967369542 -1.581 -0.9964 2531 SpecPlus_000554 CNC(=O)Oc1ccccc1OC(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L17 compound treatment 659040.0 -381000.0 -1.86 726940.0 -352000.0 -2.09 672480.0 -254429.0625 -1.45724052719674 -3.1243 -0.9896 1713087 SpecPlus_000555 COc1ccc(cc1OC)c2cc(=O)c3ccccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L18 compound treatment 800560.0 -240000.0 -1.17 877020.0 -202000.0 -1.2 705250.0 -221659.0625 -1.26955060055467 -2.1015 -0.9994 2532 SpecPlus_000556 CC(C)(C)c1ccc(OC2CCCCC2OS(=O)OCC#C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L19 compound treatment 468160.0 -572000.0 -2.8 560740.0 -518000.0 -3.08 449050.0 -477859.0625 -2.73693415886104 -4.9722 -0.9986 2060335 SpecPlus_000557 Oc1ccc2C3Oc4cc5OCOc5cc4C3COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L20 compound treatment 848060.0 -192000.0 -0.94 978520.0 -100000.0 -0.6 668930.0 -257979.0625 -1.47757312529193 -1.7392 -0.9404 2533 SpecPlus_000558 Clc1ccc(cc1)C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L21 compound treatment 921310.0 -119000.0 -0.58 1052070.0 -26600.0 -0.16 851050.0 -75859.0625 -0.434482205546588 -0.6778 -0.9123 3172732 SpecPlus_000559 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L22 compound treatment 1065300.0 25000.0 0.12 1102610.0 24000.0 0.14 896960.0 -29949.0625 -0.171533028490203 0.0537 0.2113 3055306 SpecPlus_000560 C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@H]1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L23 mock treatment 1107240.0 66900.0 0.33 1021790.0 -56800.0 -0.34 853120.0 -73789.0625 -0.422626296234745 -0.2504 -0.3961 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 L24 mock treatment 939770.0 -101000.0 -0.49 971570.0 -107000.0 -0.64 1015640.0 88730.9375 0.508205772055467 -0.3578 -0.3761 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M01 mock treatment 1101920.0 61600.0 0.3 1125010.0 46400.0 0.28 925830.0 -1079.0625 -0.00618032229072979 0.3294 0.8069 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M02 mock treatment 993400.0 -46900.0 -0.23 1135930.0 57300.0 0.34 948070.0 21160.9375 0.121199109156319 0.1343 0.3136 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M03 compound treatment 556800.0 -484000.0 -2.36 591230.0 -487000.0 -2.9 469440.0 -457469.0625 -2.62015058839318 -4.5501 -0.9965 3172733 SpecPlus_000561 Cc1c(C(=O)O)c(O)cc2C(=O)c3c(O)c(O)c(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M04 compound treatment 545540.0 -495000.0 -2.42 578080.0 -501000.0 -2.98 548000.0 -378909.0625 -2.17019878378526 -4.3672 -0.9912 2060336 SpecPlus_000562 CCOc1cccc(c1)C(=O)c2ccc(O)c(O)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M05 compound treatment 1007220.0 -33100.0 -0.16 1295520.0 217000.0 1.29 860720.0 -66189.0625 -0.379097353833775 0.4324 0.3193 3055308 SpecPlus_000563 COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)C[C@@H]31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M06 compound treatment 630000.0 -410000.0 -2.0 683120.0 -396000.0 -2.35 515420.0 -411489.0625 -2.35680048686731 -3.8761 -0.9973 2060337 SpecPlus_000564 COc1ccc(cc1O)c2oc3cc(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c(O)c3c(=O)c2OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M07 compound treatment 923520.0 -117000.0 -0.57 1152760.0 74100.0 0.44 847120.0 -79789.0625 -0.456991250761826 -0.3389 -0.3969 3055310 SpecPlus_000565 COc1c(O)cc2C(=O)O[C@H]3[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]3c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M08 compound treatment 514460.0 -526000.0 -2.57 457790.0 -621000.0 -3.69 415220.0 -511689.0625 -2.93069522746957 -5.3069 -0.9885 2060338 SpecPlus_000566 CC(C)c1ccc2c(CC[C@H]3C4=C(CC[C@@]32C)C(=O)OC4)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M09 compound treatment 976880.0 -63500.0 -0.31 1180870.0 102000.0 0.61 825000.0 -101909.0625 -0.583683383118333 -0.165 -0.1837 2060339 SpecPlus_000567 COc1cc2N3C4[C@H]5[C@H]6C[C@@H]7N(CC[C@@]74c2cc1OC)CC6=CCOC5CC3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M10 compound treatment 77850.0 -962000.0 -4.7 80900.0 -998000.0 -5.93 66400.0 -860509.0625 -4.92855913382566 -8.986 -0.9947 3055313 SpecPlus_000568 CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5C[C@H]6C7=C(CC[C@@]64C)C(=O)OC7)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M11 compound treatment 377610.0 -663000.0 -3.24 436980.0 -642000.0 -3.82 321630.0 -605279.0625 -3.46673124316783 -6.0739 -0.9977 1113269 SpecPlus_000569 CN1Cc2c3OCOc3ccc2C4C(O)Cc5cc6OCOc6cc5C41 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M12 compound treatment 896190.0 -144000.0 -0.7 1047970.0 -30700.0 -0.18 927390.0 480.9375 0.00275456588631137 -0.5103 -0.7014 2060340 SpecPlus_000570 CC(=O)/C(=C\c1ccccc1)/CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M13 compound treatment 731810.0 -309000.0 -1.51 926160.0 -152000.0 -0.91 723520.0 -203389.0625 -1.1649093140197 -2.0663 -0.9794 1064620 SpecPlus_000571 COC1=CC23CCCN3CCc4cc5OCOc5cc4C2C1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M14 compound treatment 872550.0 -168000.0 -0.82 1129340.0 50700.0 0.3 849070.0 -77839.0625 -0.445822640540524 -0.5566 -0.5675 2060341 SpecPlus_000572 COc1ccc2C(=O)C3(CC3Oc2c1)c4ccccc4OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M15 compound treatment 670590.0 -370000.0 -1.81 780240.0 -298000.0 -1.77 642450.0 -284459.0625 -1.62923712460478 -3.0081 -0.999 2060342 SpecPlus_000573 O[C@@H]1[C@H](Oc2cc(O)ccc2C1=O)c3cc(O)c(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M16 compound treatment 537760.0 -503000.0 -2.46 567170.0 -511000.0 -3.04 411260.0 -515649.0625 -2.95337609745744 -4.8788 -0.9958 1020994 SpecPlus_000574 COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CC=C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M17 compound treatment 929510.0 -111000.0 -0.54 1256530.0 178000.0 1.06 872800.0 -54109.0625 -0.309909245385918 0.1192 0.0971 2060343 SpecPlus_000575 CCCc1occc(=O)c1/C=C/O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M18 compound treatment 964960.0 -75400.0 -0.37 1248920.0 170000.0 1.01 879680.0 -47229.0625 -0.270504097528198 0.2159 0.1943 3172852 SpecPlus_000576 CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)C5CC[C@]43C)C2C1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M19 compound treatment 1066270.0 25900.0 0.13 1072960.0 -5670.0 -0.03 864050.0 -62859.0625 -0.360024804071245 -0.1542 -0.4024 3055321 SpecPlus_000577 CC(CCC(=O)O)[C@H]1CCC2C3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M20 compound treatment 48530.0 -992000.0 -4.85 99900.0 -979000.0 -5.82 73140.0 -853769.0625 -4.8899558349069 -8.9812 -0.9963 3172853 SpecPlus_000578 C[C@@H]1OC(O[C@@H]2[C@@H](O)[C@@H](O)COC2O[C@H]3CC[C@@]4(C)C(CC[C@]5(C)C4CC=C6C7CC(C)(C)CC[C@@]7(CC[C@]65C)C(=O)O)[C@]3(C)CO)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M21 compound treatment 1042780.0 2440.0 0.01 1194520.0 116000.0 0.69 887250.0 -39659.0625 -0.227146979899863 0.2736 0.377 2060344 SpecPlus_000579 CC(CCC(=O)O)[C@H]1CCC2C3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3C=C[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M22 compound treatment 967910.0 -72400.0 -0.35 1159460.0 80800.0 0.48 925570.0 -1339.0625 -0.00766947032023666 0.0688 0.1152 2060345 SpecPlus_000580 C[C@@H]1OC(O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@@]45CCC(C)(C)CC5C6=CCC7[C@@]8(C)CC[C@H](OC9OC[C@H](O)[C@H](O)[C@H]9OC%10O[C@@H](C)[C@H](O)[C@@H](O)[C@H]%10O)[C@@](C)(CO)C8CC[C@@]7(C)[C@]6(C)CC4)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M23 mock treatment 1088920.0 48600.0 0.24 1038360.0 -40300.0 -0.24 906250.0 -20659.0625 -0.118324623897439 -0.0695 -0.1946 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 M24 mock treatment 996340.0 -44000.0 -0.21 1038080.0 -40500.0 -0.24 854290.0 -72619.0625 -0.415925130101964 -0.5035 -0.956 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N01 mock treatment 1062130.0 21800.0 0.11 1124600.0 46000.0 0.27 905770.0 -21139.0625 -0.121073820259605 0.1494 0.4707 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N02 mock treatment 1108680.0 68300.0 0.33 1073980.0 -4650.0 -0.03 953510.0 26600.9375 0.152356667927539 0.2648 0.7194 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N03 compound treatment 39710.0 -1000000.0 -4.89 42160.0 -1040000.0 -6.16 47360.0 -879549.0625 -5.03761058952493 -9.2895 -0.9944 2060346 SpecPlus_000581 CC(=O)Oc1cc2c(CC=C3[C@@]2(C)CC[C@@]4(C)C5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O)c(C)c1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N04 compound treatment 960480.0 -79900.0 -0.39 1135360.0 56700.0 0.34 880570.0 -46339.0625 -0.265406629273347 -0.1837 -0.3167 2534 SpecPlus_000582 ClC(=C(c1ccc(Cl)cc1)c2ccc(Cl)cc2)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N05 compound treatment 690080.0 -350000.0 -1.71 740370.0 -338000.0 -2.01 628000.0 -298909.0625 -1.71199939009084 -3.1378 -0.997 2060347 SpecPlus_000583 COc1cc(ccc1O)c2oc3c(OC)c(O)cc(O)c3c(=O)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N06 compound treatment 727100.0 -313000.0 -1.53 908290.0 -170000.0 -1.01 651680.0 -275229.0625 -1.57637236955729 -2.3785 -0.9831 2535 SpecPlus_000584 CC1(C)C(C(Cl)Cl)C2(Cl)C(Cl)C(Cl)C1(Cl)C2(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N07 compound treatment 990560.0 -49800.0 -0.24 1147710.0 69100.0 0.41 847090.0 -79819.0625 -0.457163075534461 -0.1672 -0.2529 2060348 SpecPlus_000585 CCC/C=C/1\OC(=O)C2=C1CCC=C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N08 compound treatment 720640.0 -320000.0 -1.56 814500.0 -264000.0 -1.57 640250.0 -286659.0625 -1.64183760793138 -2.7565 -0.9997 2536 SpecPlus_000586 ClC1CC2C(C1Cl)C3(Cl)C(Cl)C(Cl)C2(Cl)C3(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N09 compound treatment 285920.0 -754000.0 -3.69 357030.0 -722000.0 -4.29 279760.0 -647149.0625 -3.70654135084264 -6.7455 -0.9974 3055363 SpecPlus_000587 COc1cc(/C=C/C(=C/C(=O)\C=C\c2ccc(O)c(OC)c2)/O)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N10 compound treatment 931130.0 -109000.0 -0.53 969620.0 -109000.0 -0.65 844380.0 -82529.0625 -0.47268457999586 -0.9552 -0.9914 2537 SpecPlus_000588 COc1ccc(cc1)C(c2ccc(OC)cc2)C(Cl)(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N11 compound treatment 875370.0 -165000.0 -0.81 995880.0 -82700.0 -0.49 773440.0 -153469.0625 -0.878992892354385 -1.2569 -0.9743 2060349 SpecPlus_000589 CCC[C@H]1CC2=C(C[C@@H](CC)CC3=C1C(=O)OC3=O)C(=O)OC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N12 compound treatment 904530.0 -136000.0 -0.66 1041440.0 -37200.0 -0.22 758190.0 -168719.0625 -0.966337151777384 -1.0687 -0.8959 2538 SpecPlus_000590 ClC1C=CC2C1C3(Cl)C(=C(Cl)C2(Cl)C3(Cl)Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N13 compound treatment 903970.0 -136000.0 -0.67 996430.0 -82200.0 -0.49 806900.0 -120009.0625 -0.687350995941695 -1.0637 -0.9897 2060350 SpecPlus_000591 CC(=O)O[C@@H]1CC2C(C)(C)[C@H](O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]13C)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N14 compound treatment 702430.0 -338000.0 -1.65 713930.0 -365000.0 -2.17 630350.0 -296559.0625 -1.69853978290106 -3.1859 -0.992 2539 SpecPlus_000592 CC1(C)C2(Cl)C(Cl)C1(Cl)C(Cl)(C(Cl)Cl)C(Cl)C2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N15 compound treatment 207400.0 -833000.0 -4.07 229330.0 -849000.0 -5.05 218900.0 -708009.0625 -4.05511653959567 -7.6067 -0.9944 3172856 SpecPlus_000593 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4C(C32)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N16 compound treatment 847700.0 -193000.0 -0.94 907050.0 -172000.0 -1.02 798110.0 -128799.0625 -0.737695654323869 -1.5584 -0.9914 2540 SpecPlus_000594 ClC1=C(Cl)C2(Cl)C3C4CC(C=C4)C3C1(Cl)C2(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N17 compound treatment 1001300.0 -39000.0 -0.19 1068960.0 -9670.0 -0.06 930920.0 4010.9375 0.0229726141330776 -0.13 -0.6485 2060351 SpecPlus_000595 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@H](CC[C@]5(C)C4=CC(=O)[C@]23C)OC(=O)C)OC61OCC(C)CC6Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N18 compound treatment 1069340.0 29000.0 0.14 1305500.0 227000.0 1.35 943330.0 16420.9375 0.0940507950799243 0.915 0.6729 2060352 SpecPlus_000596 O=C(O[C@H]1Cc2c(OC(=O)c3ccccc3)cc(OC(=O)c4ccccc4)cc2O[C@@H]1c5ccc(OC(=O)c6ccccc6)c(OC(=O)c7ccccc7)c5)c8ccccc8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N19 compound treatment 1132920.0 92600.0 0.45 1205710.0 127000.0 0.76 901550.0 -25359.0625 -0.145243838276986 0.6136 0.6874 3055370 SpecPlus_000597 COC(=O)c1c(C)c2Oc3c(Cl)c(OC(=O)C)c(Cl)c(C)c3C(=O)Oc2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N20 compound treatment 601550.0 -439000.0 -2.14 569440.0 -509000.0 -3.03 474470.0 -452439.0625 -2.59134130151464 -4.482 -0.9904 2060353 SpecPlus_000598 Cc1c(O)cc(O)c2c(=O)c(coc12)c3ccc(O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N21 compound treatment 1084230.0 43900.0 0.21 1148700.0 70100.0 0.42 966580.0 39670.9375 0.227214993872365 0.4956 0.9515 2060354 SpecPlus_000599 COc1ccc(cc1)c2coc3cc(OC(=O)C)cc(OC(=O)C)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N22 compound treatment 944230.0 -96100.0 -0.47 869920.0 -209000.0 -1.24 694670.0 -232239.0625 -1.33014747037075 -1.7556 -0.9344 2541 SpecPlus_000600 ClC1=C(Cl)C2(Cl)C3COS(=O)OCC3C1(Cl)C2(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N23 mock treatment 1046560.0 6220.0 0.03 1180610.0 102000.0 0.61 1041220.0 114310.9375 0.654715028189257 0.7457 0.8351 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 N24 mock treatment 1015710.0 -24600.0 -0.12 1106470.0 27800.0 0.17 948820.0 21910.9375 0.125494728472204 0.0986 0.4106 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O01 mock treatment 966190.0 -74100.0 -0.36 1035460.0 -43200.0 -0.26 807010.0 -119899.0625 -0.686720971775365 -0.7538 -0.9218 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O02 mock treatment 1221350.0 181000.0 0.88 1278460.0 200000.0 1.19 972890.0 45980.9375 0.263355471050012 1.3487 0.8964 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O03 compound treatment 941720.0 -98600.0 -0.48 1061410.0 -17200.0 -0.1 909440.0 -17469.0625 -0.100053923073874 -0.3951 -0.786 2060355 SpecPlus_000601 CC1=C(C=C)/C(=C/c2[nH]c(Cc3[nH]c(\C=C\4/NC(=O)C(=C4C)C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)/NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O04 compound treatment 226770.0 -814000.0 -3.97 271800.0 -807000.0 -4.8 292880.0 -634029.0625 -3.63139665027676 -7.1616 -0.9931 829 SpecPlus_000602 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O05 compound treatment 905500.0 -135000.0 -0.66 1071770.0 -6860.0 -0.04 882260.0 -44649.0625 -0.255727167081553 -0.5515 -0.7792 1055132 SpecPlus_000603 COc1cc2cc[n+]3c(C)c4cc(OC)c(OC)cc4cc3c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O06 compound treatment 1010160.0 -30200.0 -0.15 1157170.0 78500.0 0.47 863430.0 -63479.0625 -0.363575849372376 -0.0254 -0.0416 1054504 SpecPlus_000604 COc1c(OCC(O)C(C)(C)O)ccc2c(OC)c3ccoc3nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O07 compound treatment 760130.0 -280000.0 -1.37 847770.0 -231000.0 -1.37 815380.0 -111529.0625 -0.638781860210086 -1.9518 -0.9562 2060356 SpecPlus_000605 CC(C)CCCC1(C)Oc2c(CCC(C)C)c3OC4(C5CC6CC4C(=O)c3c(O)c2C=C1)C(CCC(C)C(=O)O)(OC5(C)C)C6O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O08 compound treatment 1044000.0 3660.0 0.02 1245690.0 167000.0 0.99 883600.0 -43309.0625 -0.248052327237171 0.4407 0.4303 3055414 SpecPlus_000606 OC[C@@H]1CCCN2CCCC[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O09 compound treatment 1124270.0 83900.0 0.41 1232120.0 153000.0 0.91 938500.0 11590.9375 0.0663870066856238 0.8021 0.7998 2060357 SpecPlus_000607 CC(=O)O[C@@H]1CC2C(C)(C)CCC(=O)[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C5OC54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O10 compound treatment 999490.0 -40800.0 -0.2 1128390.0 49800.0 0.3 848960.0 -77949.0625 -0.446452664706854 -0.2021 -0.3536 1024517 SpecPlus_000608 COc1cc2CCNC(C)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O11 compound treatment 861240.0 -179000.0 -0.88 1008130.0 -70500.0 -0.42 762130.0 -164779.0625 -0.943770831637934 -1.2921 -0.9546 1035065 SpecPlus_000609 Cc1nccc2c3ccccc3[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O12 compound treatment 985160.0 -55200.0 -0.27 1220500.0 142000.0 0.84 914350.0 -12559.0625 -0.0719319352858789 0.2899 0.3263 1592184 SpecPlus_000610 O=C1CCCC2C3CC(CN21)[C@@H]4CCCCN4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O13 compound treatment 554400.0 -486000.0 -2.37 708000.0 -371000.0 -2.2 512060.0 -414849.0625 -2.37604486140247 -4.015 -0.9994 297849 SpecPlus_000611 COc1ccc2c(c1)[nH]c3c(C)nccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O14 compound treatment 1100000.0 59700.0 0.29 1145760.0 67100.0 0.4 896070.0 -30839.0625 -0.176630496745054 0.2968 0.5654 2060358 SpecPlus_000612 C[C@@H]1CCC2[C@](C)(CO)[C@@H](O)CC[C@]2(C)[C@]31CC[C@@](CO)(CCO)O3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O15 compound treatment 830420.0 -210000.0 -1.03 1005150.0 -73500.0 -0.44 785640.0 -141269.0625 -0.809117484815987 -1.3116 -0.9521 2060359 SpecPlus_000613 COc1ccc(cc1)c2c(O)c3c(OC)c4C=CC(C)(C)Oc4cc3oc2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O16 compound treatment 1035070.0 -5270.0 -0.03 1211870.0 133000.0 0.79 1039680.0 112770.9375 0.64589468986064 0.8155 0.7975 1052338 SpecPlus_000614 COc1cc2C(C)NCCc2cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O17 compound treatment 1045080.0 4740.0 0.02 1133960.0 55300.0 0.33 879170.0 -47739.0625 -0.273425118662999 0.0455 0.1062 2060360 SpecPlus_000615 C1CN=C(C1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O18 compound treatment 924160.0 -116000.0 -0.57 1091640.0 13000.0 0.08 958450.0 31540.9375 0.180650480488169 -0.1787 -0.2976 852250 SpecPlus_000616 C1CCC(NC1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O19 compound treatment 983580.0 -56800.0 -0.28 1250080.0 171000.0 1.02 821070.0 -105839.0625 -0.606192428333571 0.0786 0.0645 1040989 SpecPlus_000617 c1ccc2c(c1)[nH]c3ncccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O20 compound treatment 908370.0 -132000.0 -0.64 1039520.0 -39100.0 -0.23 903590.0 -23319.0625 -0.133559753737778 -0.5836 -0.8358 3172862 SpecPlus_000618 O=c1cccc2C3CNC[C@@H](C3)Cn21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O21 compound treatment 1028640.0 -11700.0 -0.06 1254650.0 176000.0 1.05 912400.0 -14509.0625 -0.0831005455071803 0.5234 0.4977 1084508 SpecPlus_000619 COc1ccc2cc3-c4cc(OC)c(OC)cc4CC[n+]3cc2c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O22 compound treatment 306720.0 -734000.0 -3.58 253950.0 -825000.0 -4.9 238190.0 -688719.0625 -3.9446332107911 -7.1782 -0.9911 2060361 SpecPlus_000620 C/C=C(/C)\C(=O)O[C@@H]1[C@H](OC(=O)C)[C@]2(CO)[C@H](O)C[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(=O)O)[C@](C)(CO)C5CC[C@]43C)C2CC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O23 mock treatment 1054680.0 14300.0 0.07 1131220.0 52600.0 0.31 979200.0 52290.9375 0.299495948227659 0.3939 0.898 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 O24 mock treatment 954050.0 -86300.0 -0.42 1007320.0 -71300.0 -0.42 852110.0 -74799.0625 -0.428411063580137 -0.7356 -1.0 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P01 mock treatment 840840.0 -199000.0 -0.97 859520.0 -219000.0 -1.3 889190.0 -37719.0625 -0.216035644602774 -1.4397 -0.8771 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P02 mock treatment 1072020.0 31700.0 0.15 1162960.0 84300.0 0.5 985760.0 58850.9375 0.337068298510602 0.5735 0.9195 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P03 compound treatment 1013920.0 -26400.0 -0.13 1228640.0 150000.0 0.89 916600.0 -10309.0625 -0.0590450773382233 0.4064 0.4499 2060362 SpecPlus_000621 COc1ccc(cc1)c2c(OC)c3c(OC)c4C=CC(C)(C)Oc4cc3oc2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P04 compound treatment 999220.0 -41100.0 -0.2 1058140.0 -20500.0 -0.12 881280.0 -45629.0625 -0.261340109654309 -0.3372 -0.9595 2542 SpecPlus_000622 CCCCOC(=O)c1ccccc1C(=O)OCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P05 compound treatment 35360.0 -1000000.0 -4.91 39640.0 -1040000.0 -6.18 41600.0 -885309.0625 -5.07060094587093 -9.3295 -0.9946 2060363 SpecPlus_000623 COc1cc(O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P06 compound treatment 765920.0 -274000.0 -1.34 939740.0 -139000.0 -0.83 748610.0 -178299.0625 -1.02120652917229 -1.8405 -0.9806 2543 SpecPlus_000624 CCCCCCCCCc1ccc(O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P07 compound treatment 974760.0 -65600.0 -0.32 1062400.0 -16200.0 -0.1 888530.0 -38379.0625 -0.219815789600752 -0.3676 -0.9182 2060364 SpecPlus_000625 CC(=O)O[C@@H]1C[C@H](OC(=O)C)[C@@]2(C)C(C[C@@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C=C43)c5ccoc5)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P08 compound treatment 1023080.0 -17300.0 -0.08 1128280.0 49700.0 0.3 998800.0 71890.9375 0.411754799682792 0.3595 0.6999 2544 SpecPlus_000626 CCOCN(C(=O)CCl)c1c(C)cccc1CC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P09 compound treatment 1007590.0 -32700.0 -0.16 1181480.0 103000.0 0.61 946410.0 19500.9375 0.111691471737159 0.3252 0.5066 3172979 SpecPlus_000627 C[C@H]1C2C(CC3C4CC=C5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@@]61CC[C@@H](C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P10 compound treatment 913570.0 -127000.0 -0.62 1029650.0 -49000.0 -0.29 742620.0 -184289.0625 -1.05551420877516 -1.1351 -0.9023 2545 SpecPlus_000628 CCCCOC(=O)c1ccccc1C(=O)OCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P11 compound treatment 1104160.0 63800.0 0.31 1120210.0 41600.0 0.25 934680.0 7770.9375 0.0445079856367153 0.3485 0.8703 2060365 SpecPlus_000629 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)C3OC3[C@]2(C)C4CC[C@@]5(C)[C@@H](OC(=O)C6OC65[C@]14C)c7ccoc7 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P12 compound treatment 839620.0 -201000.0 -0.98 952380.0 -126000.0 -0.75 722930.0 -203979.0625 -1.1682885345482 -1.6741 -0.9848 1304 SpecPlus_000630 ClC1=C(Cl)C2(Cl)C3C4CC(C5OC54)C3C1(Cl)C2(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P13 compound treatment 770720.0 -270000.0 -1.32 870910.0 -208000.0 -1.24 674440.0 -252469.0625 -1.44601464205123 -2.3085 -0.9979 2060366 SpecPlus_000631 CC1(C)C=CC(=O)[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P14 compound treatment 56660.0 -984000.0 -4.81 50050.0 -1030000.0 -6.12 35260.0 -891649.0625 -5.10691324782121 -9.2546 -0.9945 2060367 SpecPlus_000632 CS(=O)(=O)CCCCN=C=S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P15 compound treatment 1030940.0 -9400.0 -0.05 1146610.0 68000.0 0.4 878150.0 -48759.0625 -0.279267160932603 0.0457 0.0925 2060368 SpecPlus_000633 CNC(Cc1c[nH]c2ccccc12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P16 compound treatment 1025130.0 -15200.0 -0.07 1260610.0 182000.0 1.08 1065700.0 138790.9375 0.794924042659749 1.0408 0.774 2060369 SpecPlus_000634 C[C@@]12CCC(=O)C[C@H]2CC[C@]3(CC4CC[C@H]31)C[C@]4(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P17 compound treatment 1025450.0 -14900.0 -0.07 1238800.0 160000.0 0.95 832250.0 -94659.0625 -0.542159063064776 0.1949 0.1774 2060370 SpecPlus_000635 COc1cc2OCOc2cc1c3coc4c5C=CC(C)(C)Oc5c(OC)cc4c3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P18 compound treatment 1069850.0 29500.0 0.14 1246980.0 168000.0 1.0 922530.0 -4379.0625 -0.0250810472806246 0.6468 0.6392 2060371 SpecPlus_000636 COC(=O)C[C@H]1C(C)(C)C2(O)OC34CC2C(=O)[C@]1(C)C4CC[C@@]5(C)[C@@H](OC(=O)C=C35)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P19 compound treatment 1113050.0 72700.0 0.36 1195460.0 117000.0 0.69 886770.0 -40139.0625 -0.22989617626203 0.4735 0.5821 2060372 SpecPlus_000637 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2CC3=C(CC[C@@]4(C)[C@@H](OC(=O)C=C34)c5ccoc5)[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P20 compound treatment 940930.0 -99400.0 -0.49 1101320.0 22700.0 0.13 925410.0 -1499.0625 -0.00858586910762549 -0.2075 -0.4115 2060373 SpecPlus_000638 COc1c(O)cc2c(cc(=O)oc2c1OC)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P21 compound treatment 956830.0 -83500.0 -0.41 974680.0 -104000.0 -0.62 967200.0 40290.9375 0.230766039173496 -0.4592 -0.5919 2060374 SpecPlus_000639 CCC(C)C(OC(=O)C)C(=O)O[C@H]1[C@H](O)C2[C@@]3(C)C=CC(=O)C(C)(C)C3C[C@@H](OC(=O)C(O)C(C)C)[C@@]2(C)[C@]45O[C@@H]5C[C@@H](c6ccoc6)[C@]14C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P22 compound treatment 981170.0 -59200.0 -0.29 1023770.0 -54900.0 -0.33 1075520.0 148610.9375 0.851168018235739 0.1362 0.1424 3055472 SpecPlus_000640 CC(C)CCCC(C)[C@H]1CCC2C3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P23 mock treatment 1015540.0 -24800.0 -0.12 1174170.0 95500.0 0.57 938090.0 11180.9375 0.0640387347929399 0.295 0.5048 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1082 P24 mock treatment 965960.0 -74400.0 -0.36 947540.0 -131000.0 -0.78 960720.0 33810.9375 0.193651888284249 -0.5481 -0.6217 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A01 mock treatment 777120.0 -247000.0 -1.21 759520.0 -331000.0 -1.97 704010.0 -167054.84375 -0.956805351499573 -2.3865 -0.9544 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A02 mock treatment 848480.0 -176000.0 -0.86 915100.0 -176000.0 -1.04 789890.0 -81174.84375 -0.464928302368615 -1.3671 -0.9562 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A03 compound treatment 936040.0 -88100.0 -0.43 892110.0 -199000.0 -1.18 742590.0 -128474.84375 -0.73583869389044 -1.3554 -0.9305 1492782 SpecPlus_000641 OCNC(=O)c1cccnc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A04 compound treatment 983840.0 -40300.0 -0.2 872850.0 -218000.0 -1.3 740060.0 -131004.84375 -0.750329249716026 -1.2951 -0.8576 2060375 SpecPlus_000642 CC(=O)O[C@H]1C[C@@H](O)C(C)(C)C2CC(=O)[C@]3(C)C(CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6)[C@@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A05 compound treatment 989600.0 -34600.0 -0.17 866780.0 -224000.0 -1.33 800530.0 -70534.84375 -0.403987783007257 -1.0997 -0.7844 2060376 SpecPlus_000643 CC(=O)Oc1cccc2C(=O)c3cc(cc(OC(=O)C)c3C(=O)c12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A06 compound treatment 1006970.0 -17200.0 -0.08 928180.0 -163000.0 -0.97 760980.0 -110084.84375 -0.630510108264935 -0.9707 -0.8388 3055475 SpecPlus_000644 COc1ccc(/C=C/C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A07 compound treatment 996320.0 -27900.0 -0.14 935680.0 -155000.0 -0.92 762300.0 -108764.84375 -0.622949818268977 -0.9706 -0.8658 1009851 SpecPlus_000645 O=C1c2ccccc2C(=O)c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A08 compound treatment 1019330.0 -4860.0 -0.02 960160.0 -131000.0 -0.78 735650.0 -135414.84375 -0.77558749129343 -0.9098 -0.8288 1047043 SpecPlus_000646 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A09 compound treatment 966820.0 -57400.0 -0.28 902940.0 -188000.0 -1.12 703610.0 -167454.84375 -0.959096348468045 -1.3603 -0.9078 1693 SpecPlus_000647 NCCCNCCSP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A10 compound treatment 1040240.0 16100.0 0.08 991360.0 -99400.0 -0.59 725860.0 -145204.84375 -0.831659642096785 -0.7761 -0.7584 2060377 SpecPlus_000648 COc1c(ccc2OC(C)(C)CCc12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A11 compound treatment 49650.0 -975000.0 -4.76 31290.0 -1060000.0 -6.3 38080.0 -832984.84375 -4.77091437953612 -9.1408 -0.9907 3172984 SpecPlus_000649 COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A12 compound treatment 1032170.0 7980.0 0.04 864480.0 -226000.0 -1.35 691310.0 -179754.84375 -1.02954450524856 -1.3487 -0.7959 2060378 SpecPlus_000650 Oc1nc2cc(Cl)c(Cl)cc2nc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A13 compound treatment 1020430.0 -3760.0 -0.02 850650.0 -240000.0 -1.43 661300.0 -209764.84375 -1.20142655280818 -1.5285 -0.8191 2060379 SpecPlus_000651 COc1ccc(cc1)c2coc3c(OC)c(OC)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A14 compound treatment 964240.0 -59900.0 -0.29 850980.0 -240000.0 -1.43 700900.0 -170164.84375 -0.974617852929443 -1.5549 -0.8877 2060380 SpecPlus_000652 CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3(F)[C@@H](O)C[C@@]21C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A15 compound treatment 944420.0 -79800.0 -0.39 848990.0 -242000.0 -1.44 685950.0 -185114.84375 -1.06024386462609 -1.6671 -0.9119 1111718 SpecPlus_000653 NC1(CCC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A16 compound treatment 1062500.0 38300.0 0.19 916530.0 -174000.0 -1.04 760110.0 -110954.84375 -0.635493026671362 -0.8569 -0.6969 1001282 SpecPlus_000654 NCCS 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A17 compound treatment 1091110.0 66900.0 0.33 892400.0 -198000.0 -1.18 725980.0 -145084.84375 -0.830972343006243 -0.9719 -0.657 2060381 SpecPlus_000655 COc1c(Cl)c(C)c2Oc3c(Cl)c(OC)c(Cl)c(C)c3C(=O)Oc2c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A18 compound treatment 966490.0 -57700.0 -0.28 947060.0 -144000.0 -0.85 774440.0 -96624.84375 -0.553418060275849 -0.9756 -0.9236 1001451 SpecPlus_000656 Cc1cc(C)cc(OCC2CNC(=O)O2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A19 compound treatment 1009180.0 -15000.0 -0.07 821700.0 -269000.0 -1.6 746890.0 -124174.84375 -0.711210476479365 -1.3766 -0.7856 2060382 SpecPlus_000657 C/C/1=C\CC(C)(C)\C=C\CC2(C)OC2CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A20 compound treatment 565510.0 -459000.0 -2.24 532920.0 -558000.0 -3.32 435100.0 -435964.84375 -2.49698533847915 -4.6506 -0.9857 2060383 SpecPlus_000658 COc1cc(cc(OC)c1OC)c2oc3cc(O)ccc3c(=O)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A21 compound treatment 311410.0 -713000.0 -3.48 326990.0 -764000.0 -4.54 271740.0 -599324.84375 -3.43262850040315 -6.6146 -0.9912 2060384 SpecPlus_000659 CO[C@@H]1C[C@H](O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)O[C@H](C)[C@H]1O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A22 compound treatment 933690.0 -90500.0 -0.44 892290.0 -198000.0 -1.18 693660.0 -177404.84375 -1.01608489805879 -1.5232 -0.941 2060385 SpecPlus_000660 COC(=O)C[C@H]1C(C)(C)[C@@H](OC(=O)C(C)C)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A23 mock treatment 953440.0 -70700.0 -0.35 947200.0 -144000.0 -0.85 756320.0 -114744.84375 -0.657200222947635 -1.0718 -0.9474 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 A24 mock treatment 937920.0 -86300.0 -0.42 855720.0 -235000.0 -1.4 766560.0 -104504.84375 -0.598550700554749 -1.3958 -0.8847 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B01 mock treatment 1040160.0 16000.0 0.08 990500.0 -100000.0 -0.6 829080.0 -41984.84375 -0.240467874382561 -0.4379 -0.6763 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B02 mock treatment 1110240.0 86100.0 0.42 974530.0 -116000.0 -0.69 775250.0 -95814.84375 -0.548778791414693 -0.4731 -0.484 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B03 compound treatment 379260.0 -645000.0 -3.15 318720.0 -772000.0 -4.59 254880.0 -616184.84375 -3.52919402262425 -6.5073 -0.9871 193 SpecPlus_000661 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B04 compound treatment 957230.0 -67000.0 -0.33 918580.0 -172000.0 -1.02 774890.0 -96174.84375 -0.550840688686318 -1.098 -0.9091 2308 SpecPlus_000662 Cc1ccc(cc1NC(=O)c2cccc(NC(=O)Nc3cccc(c3)C(=O)Nc4cc(ccc4C)C(=O)Nc5ccc(c6cc(cc(c56)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)c2)C(=O)Nc7ccc(c8cc(cc(c78)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B05 compound treatment 1112120.0 87900.0 0.43 904800.0 -186000.0 -1.11 783850.0 -87214.84375 -0.499522356592543 -0.6787 -0.5273 907463 SpecPlus_000663 Cc1nc2ccccn2c(=O)c1CCN3CCC(CC3)C(=O)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B06 compound treatment 1046630.0 22400.0 0.11 980320.0 -110000.0 -0.66 776860.0 -94204.84375 -0.539557528616593 -0.6273 -0.7321 1002022 SpecPlus_000664 NC(CCC(=O)O)C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B07 compound treatment 1051600.0 27400.0 0.13 1078850.0 -11900.0 -0.07 751280.0 -119784.84375 -0.686066784750383 -0.3596 -0.5118 2060386 SpecPlus_000665 CCN1C[C@]2(C)CC[C@H](OC)[C@@]34C2[C@H](O)[C@]5(OCO[C@]65C[C@H](OC)[C@H]7C[C@]4(O)C6[C@H]7O)C13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B08 compound treatment 993870.0 -30300.0 -0.15 942480.0 -148000.0 -0.88 738350.0 -132714.84375 -0.760123261756244 -1.0334 -0.8806 790507 SpecPlus_000666 OC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B09 compound treatment 1037530.0 13300.0 0.07 927520.0 -163000.0 -0.97 806080.0 -64984.84375 -0.372200200069707 -0.7376 -0.7082 4480 SpecPlus_000667 CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B10 compound treatment 1054100.0 29900.0 0.15 921730.0 -169000.0 -1.01 776990.0 -94074.84375 -0.53881295460184 -0.807 -0.7019 2060387 SpecPlus_000668 OC(=O)CCCCCCCn1ccnc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B11 compound treatment 938940.0 -85200.0 -0.42 899480.0 -191000.0 -1.14 734190.0 -136874.84375 -0.783949630228354 -1.3497 -0.9355 1837 SpecPlus_000669 CS(=O)(=O)c1ccc(cc1)C2=C(C(=O)OC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B12 compound treatment 1109360.0 85200.0 0.42 1076750.0 -14000.0 -0.08 753360.0 -117704.84375 -0.674153600514328 -0.197 -0.2473 1044852 SpecPlus_000670 OC(=O)c1cc2cc(Cl)ccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B13 compound treatment 127280.0 -897000.0 -4.38 151330.0 -939000.0 -5.59 132640.0 -738424.84375 -4.22932269618932 -8.1971 -0.9919 2060388 SpecPlus_000671 CC(=O)OC[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CCc5c(C)c(OC(=O)C)c(OC(=O)C)cc5[C@]4(C)CC[C@@]3(C)C2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B14 compound treatment 1012050.0 -12100.0 -0.06 966050.0 -125000.0 -0.74 735570.0 -135494.84375 -0.776045690687125 -0.9104 -0.8469 2060389 SpecPlus_000672 OC(=O)Cc1c[nH]cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B15 compound treatment 859740.0 -164000.0 -0.8 716180.0 -375000.0 -2.23 634460.0 -236604.84375 -1.35515244939266 -2.5322 -0.9282 2060390 SpecPlus_000673 CC(=O)O[C@H]1CC[C@@]2(C)C(C[C@H](OC(=O)C)[C@]3(C)C2CC[C@@]4(C)C(OC(=O)C=C43)c5ccoc5)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B16 compound treatment 981520.0 -42700.0 -0.21 953560.0 -137000.0 -0.82 788200.0 -82864.84375 -0.474607764560409 -0.8653 -0.8953 2060391 SpecPlus_000674 OC1/C(=C/C(=O)O)/CCCc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B17 compound treatment 982310.0 -41900.0 -0.2 1015540.0 -75200.0 -0.45 819200.0 -51864.84375 -0.297055499503822 -0.5478 -0.9535 3173106 SpecPlus_000675 COC(=O)c1c(C)c2Oc3c(Cl)c(O)c(Cl)c(C)c3C(=O)Oc2c(C)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B18 compound treatment 976960.0 -47200.0 -0.23 979260.0 -111000.0 -0.66 889320.0 18255.15625 0.104556269069336 -0.4556 -0.642 1014792 SpecPlus_000676 OC(=O)c1cc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B19 compound treatment 632350.0 -392000.0 -1.91 599910.0 -491000.0 -2.92 472830.0 -398234.84375 -2.28088704942802 -4.1073 -0.985 2060392 SpecPlus_000677 CCOc1ccc(cc1)C(=O)c2ccc(O)c(O)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B20 compound treatment 929840.0 -94300.0 -0.46 609280.0 -481000.0 -2.86 739040.0 -132024.84375 -0.756171291985629 -2.3557 -0.786 348755 SpecPlus_000678 OC(=O)c1cc2cc(F)ccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B21 compound treatment 1007320.0 -16900.0 -0.08 927110.0 -164000.0 -0.97 799490.0 -71574.84375 -0.409944375125284 -0.846 -0.7988 2060393 SpecPlus_000679 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)CCC1(C)C)/C=C/C=C(\C)/C=C/C2=C(C)C(=O)CCC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B22 compound treatment 168250.0 -856000.0 -4.18 215400.0 -875000.0 -5.21 163720.0 -707344.84375 -4.05131223173904 -7.7587 -0.9934 3173108 SpecPlus_000680 CC[C@H]([C@@H]1O[C@@H]([C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@H]2O[C@@]3(O[C@@]4(CC[C@](C)(O4)C5CC[C@](O)(CC)[C@H](C)O5)[C@H](O)C=C3)[C@H](C)C[C@@H]2C)[C@@H](C)C[C@H]1C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B23 mock treatment 995590.0 -28600.0 -0.14 972400.0 -118000.0 -0.7 857760.0 -13304.84375 -0.0762033917431122 -0.531 -0.7359 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 B24 mock treatment 939000.0 -85200.0 -0.42 838760.0 -252000.0 -1.5 812820.0 -58244.84375 -0.333596901150952 -1.298 -0.8161 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C01 mock treatment 991420.0 -32800.0 -0.16 1117140.0 26400.0 0.16 784960.0 -86104.84375 -0.493164840005033 -0.2865 -0.5289 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C02 mock treatment 1016350.0 -7840.0 -0.04 1022120.0 -68600.0 -0.41 784000.0 -87064.84375 -0.498663232729366 -0.5456 -0.8453 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C03 compound treatment 1076850.0 52700.0 0.26 1019650.0 -71100.0 -0.42 855560.0 -15504.84375 -0.0888038750697087 -0.1468 -0.2919 3055569 SpecPlus_000681 OCc1cccnc1.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C04 compound treatment 1113370.0 89200.0 0.44 1043440.0 -47300.0 -0.28 813170.0 -57894.84375 -0.331592278803539 -0.1023 -0.1661 2060394 SpecPlus_000682 CC12C[C@@H](O)C3C(CCC4CC(O)CCC43C)C2=CCC1C5=CC(=O)OC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C05 compound treatment 1175040.0 151000.0 0.74 1008330.0 -82400.0 -0.49 785690.0 -85374.84375 -0.488983770537572 -0.1397 -0.1382 3202 SpecPlus_000683 COc1ccccc1N2CCN(CCCNc3cc(=O)n(C)c(=O)n3C)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C06 compound treatment 514880.0 -509000.0 -2.49 345610.0 -745000.0 -4.43 313710.0 -557354.84375 -3.19224564348622 -5.8379 -0.9728 2576 SpecPlus_000684 S=C=NCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C07 compound treatment 1116680.0 92500.0 0.45 1151090.0 60300.0 0.36 746170.0 -124894.84375 -0.715334271022614 0.0551 0.06 3055573 SpecPlus_000685 OC[C@H]1OC([C@H](O)[C@@H]1O)n2cnc3c(=O)[nH]cnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C08 compound treatment 994790.0 -29400.0 -0.14 782670.0 -308000.0 -1.83 676120.0 -194944.84375 -1.11654511512629 -1.7852 -0.8303 1000656 SpecPlus_000686 OC1=C([C@H]2CC[C@@H](CC2)c3ccc(Cl)cc3)C(=O)c4ccccc4C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C09 compound treatment 1119450.0 95300.0 0.47 1020960.0 -69800.0 -0.41 780320.0 -90744.84375 -0.519740404839309 -0.2709 -0.3337 2060395 SpecPlus_000687 CC(C)C(NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(N)CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C10 compound treatment 1002080.0 -22100.0 -0.11 942370.0 -148000.0 -0.88 737330.0 -133734.84375 -0.765965304025848 -1.014 -0.8642 2060396 SpecPlus_000688 OC[C@H]1O[C@@H](Oc2ccc(C(=O)/C=C/c3ccccc3)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C11 compound treatment 578080.0 -446000.0 -2.18 517650.0 -573000.0 -3.41 439600.0 -431464.84375 -2.47121162258384 -4.6527 -0.9815 2060397 SpecPlus_000689 COc1ccc2C(=O)/C(=C/c3ccc(OC)c(O)c3)/COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C12 compound treatment 1044400.0 20200.0 0.1 1008450.0 -82300.0 -0.49 719710.0 -151354.84375 -0.866883720487043 -0.726 -0.7257 2060398 SpecPlus_000690 COC1=C(Cl)C(=O)C2(Oc3cc(O)c(Cl)c(C)c3C2=O)C(=C1Cl)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C13 compound treatment 194720.0 -829000.0 -4.05 191900.0 -899000.0 -5.35 224930.0 -646134.84375 -3.7007324206386 -7.5623 -0.9871 2060399 SpecPlus_000691 CC(C)CCCC(C)[C@H]1CCC2C3C[C@@H](O)[C@@]4(O)C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C14 compound treatment 974260.0 -49900.0 -0.24 938560.0 -152000.0 -0.9 672570.0 -198494.84375 -1.13687771322148 -1.3197 -0.8957 1898 SpecPlus_000692 OC(=O)CC[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C15 compound treatment 560130.0 -464000.0 -2.27 426460.0 -664000.0 -3.95 478790.0 -392274.84375 -2.24675119459778 -4.8868 -0.9622 2060400 SpecPlus_000693 CC(C)c1ccc2c(CCC3[C@](C)(CN)CCC[C@@]32C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C16 compound treatment 1029550.0 5360.0 0.03 975770.0 -115000.0 -0.68 702560.0 -168504.84375 -0.965110215510284 -0.9368 -0.7919 1087705 SpecPlus_000694 CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C17 compound treatment 422210.0 -602000.0 -2.94 380270.0 -710000.0 -4.22 283300.0 -587764.84375 -3.36641868801431 -6.0809 -0.9886 2060401 SpecPlus_000695 CO[C@@H]1C[C@H]2N3C[C@@H](O)C2(C=C1)c4cc5OCOc5cc4[C@@H]3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C18 compound treatment 931300.0 -92900.0 -0.45 970400.0 -120000.0 -0.72 694780.0 -176284.84375 -1.00967010654707 -1.2581 -0.9545 1000009 SpecPlus_000696 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C19 compound treatment 1036000.0 11800.0 0.06 819400.0 -271000.0 -1.61 740820.0 -130244.84375 -0.745976355475929 -1.3289 -0.7472 2060402 SpecPlus_000697 COc1ccc2CC[C@H]3CC(=O)CC[C@]3(C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C20 compound treatment 911210.0 -113000.0 -0.55 908840.0 -182000.0 -1.08 739170.0 -131894.84375 -0.755426717970876 -1.3793 -0.9645 1552436 SpecPlus_000698 COc1ccc(cc1)c2cc(=O)c3cc(OC)ccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C21 compound treatment 862610.0 -162000.0 -0.79 840400.0 -250000.0 -1.49 731130.0 -139934.84375 -0.801475757037165 -1.778 -0.9529 2060403 SpecPlus_000699 COc1ccc(C2COc3cc(O)ccc3C2)c(OC)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C22 compound treatment 974880.0 -49300.0 -0.24 1019290.0 -71500.0 -0.42 862080.0 -8984.84375 -0.0514606244836136 -0.4141 -0.8432 2060404 SpecPlus_000700 CC1=C(Cl)C(=O)C(=C(O)C21Oc3cc(O)c(Cl)c(C)c3C2=O)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C23 mock treatment 1023840.0 -346.0 0.0 1010190.0 -80600.0 -0.48 831210.0 -39854.84375 -0.228268315525447 -0.4093 -0.7714 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 C24 mock treatment 933370.0 -90800.0 -0.44 927460.0 -163000.0 -0.97 758270.0 -112794.84375 -0.646031612726333 -1.1897 -0.9535 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D01 mock treatment 971040.0 -53100.0 -0.26 1099810.0 9070.0 0.05 786090.0 -84974.84375 -0.486692773569099 -0.3998 -0.7213 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D02 mock treatment 1133830.0 110000.0 0.54 1138130.0 47400.0 0.28 826100.0 -44964.84375 -0.257535801797678 0.3233 0.4915 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D03 compound treatment 1100490.0 76300.0 0.37 970640.0 -120000.0 -0.71 755650.0 -115414.84375 -0.661037642869826 -0.5787 -0.5554 2060405 SpecPlus_000701 CC1(C)[C@H](CC(=O)O)[C@@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4[C@]3(O)C[C@@H](C1=O)C2=O)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D04 compound treatment 858680.0 -166000.0 -0.81 822500.0 -268000.0 -1.6 609150.0 -261914.84375 -1.50011528257273 -2.2539 -0.9656 2272 SpecPlus_000702 OC(=O)C(Cc1ccc(O)c(O)c1)OC(=O)/C=C/c2ccc(O)c(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D05 compound treatment 1030790.0 6600.0 0.03 947080.0 -144000.0 -0.85 727170.0 -143894.84375 -0.824156627025039 -0.9504 -0.8004 2060406 SpecPlus_000703 COc1ccccc1/C=C\C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D06 compound treatment 1193000.0 169000.0 0.82 1092240.0 1500.0 0.01 777840.0 -93224.84375 -0.533944586043836 0.1731 0.1761 832189 SpecPlus_000704 CC(=O)CC(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D07 compound treatment 1096390.0 72200.0 0.35 1061890.0 -28900.0 -0.17 730170.0 -140894.84375 -0.806974149761498 -0.3613 -0.4026 2060407 SpecPlus_000705 COc1ccc(/C=C/C(=O)O)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D08 compound treatment 1041370.0 17200.0 0.08 965160.0 -126000.0 -0.75 769550.0 -101514.84375 -0.58142549821542 -0.7184 -0.7561 2553 SpecPlus_000706 CNNC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D09 compound treatment 1024160.0 -25.8 0.0 976640.0 -114000.0 -0.68 785320.0 -85744.84375 -0.491102942733408 -0.6753 -0.8063 1014978 SpecPlus_000707 OCC(O)C(O)C(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D10 compound treatment 1117600.0 93400.0 0.46 923450.0 -167000.0 -0.99 763960.0 -107104.84375 -0.613442180849818 -0.665 -0.53 2575 SpecPlus_000708 CCS(=O)(=O)CCn1c(C)ncc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D11 compound treatment 902240.0 -122000.0 -0.6 839720.0 -251000.0 -1.49 651840.0 -219224.84375 -1.25560863111255 -1.9307 -0.9467 3173115 SpecPlus_000709 C[C@H]1[C@H]2[C@H](CC3C4CC[C@H]5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)O[C@]61CCC(C)CN6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D12 compound treatment 1038980.0 14800.0 0.07 942170.0 -149000.0 -0.88 777800.0 -93264.84375 -0.534173685740684 -0.7768 -0.7505 1923 SpecPlus_000710 NC1(CC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D13 compound treatment 1118080.0 93900.0 0.46 1156360.0 65600.0 0.39 868040.0 -3024.84375 -0.0173247696533794 0.4801 0.7969 2060408 SpecPlus_000711 COC(=O)C[C@H]1C(C)(C)[C@H](C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D14 compound treatment 310160.0 -714000.0 -3.49 307950.0 -783000.0 -4.65 256350.0 -614714.84375 -3.52077460876512 -6.7344 -0.9904 383 SpecPlus_000712 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D15 compound treatment 970600.0 -53600.0 -0.26 929300.0 -161000.0 -0.96 747920.0 -123144.84375 -0.705311159285549 -1.1126 -0.9122 1015281 SpecPlus_000713 COc1cc(O)c(C(=O)C)c(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D16 compound treatment 1029220.0 5030.0 0.02 970500.0 -120000.0 -0.72 737600.0 -133464.84375 -0.764418881072129 -0.84 -0.8023 2060409 SpecPlus_000714 N[C@@H](CCCNC(=N)NC(CCC(=O)O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D17 compound treatment 870800.0 -153000.0 -0.75 829440.0 -261000.0 -1.55 691740.0 -179324.84375 -1.02708168350745 -1.9228 -0.9577 2060410 SpecPlus_000715 CC1(C)[C@H](O)CC(=O)[C@@]2(C)C1C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)C5OC543)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D18 compound treatment 948290.0 -75900.0 -0.37 923960.0 -167000.0 -0.99 717280.0 -153784.84375 -0.880801527070511 -1.2952 -0.9404 115 SpecPlus_000716 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D19 compound treatment 805350.0 -219000.0 -1.07 801070.0 -290000.0 -1.72 586480.0 -284584.84375 -1.62995753576089 -2.5529 -0.9814 2060411 SpecPlus_000717 O[C@H]1Cc2ccc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D20 compound treatment 737460.0 -287000.0 -1.4 1034400.0 -56300.0 -0.34 742330.0 -128734.84375 -0.737327841919946 -1.4279 -0.8824 397 SpecPlus_000718 CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D21 compound treatment 959550.0 -64600.0 -0.32 951260.0 -139000.0 -0.83 711860.0 -159204.84375 -0.911844535993308 -1.1877 -0.9334 2060412 SpecPlus_000719 C[C@]12[C@H](CC[C@]2(O)[C@@]34OC4C[C@@H]5C[C@@H](O)CC[C@]5(C)C3[C@H](O)C1=O)C6=CC(=O)OC6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D22 compound treatment 973290.0 -50900.0 -0.25 987040.0 -104000.0 -0.62 777440.0 -93624.84375 -0.536235583012308 -0.8092 -0.9473 873168 SpecPlus_000720 OC(=O)c1cc(O)c2ccc(Cl)cc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D23 mock treatment 982250.0 -41900.0 -0.2 1106600.0 15900.0 0.09 839200.0 -31864.84375 -0.182505651080217 -0.1692 -0.5832 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 D24 mock treatment 993130.0 -31100.0 -0.15 1012160.0 -78600.0 -0.47 881390.0 10325.15625 0.0591372541693767 -0.3232 -0.6532 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E01 mock treatment 975090.0 -49100.0 -0.24 1138810.0 48100.0 0.29 825300.0 -45764.84375 -0.262117795734623 -0.1248 -0.2736 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E02 mock treatment 1117650.0 93500.0 0.46 1078940.0 -11800.0 -0.07 843920.0 -27144.84375 -0.155471886852247 0.1334 0.2736 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E03 compound treatment 1100500.0 76300.0 0.37 1004360.0 -86400.0 -0.51 870140.0 -924.84375 -0.00529703556890091 -0.0844 -0.1329 2060413 SpecPlus_000721 CC(C)CCCC(C)[C@H]1CCC2C3CC[C@H]4CC(=O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E04 compound treatment 867600.0 -157000.0 -0.77 762050.0 -329000.0 -1.95 651170.0 -219894.84375 -1.25944605103474 -2.2973 -0.9385 1091368 SpecPlus_000722 CNc1ccccc1C(=O)N2CCc3c([nH]c4ccccc34)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E05 compound treatment 66340.0 -958000.0 -4.68 47840.0 -1040000.0 -6.2 47140.0 -823924.84375 -4.71902329820023 -9.007 -0.9908 1095093 SpecPlus_000723 CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E06 compound treatment 943490.0 -80700.0 -0.39 981800.0 -109000.0 -0.65 716750.0 -154314.84375 -0.883837098053737 -1.1119 -0.9548 1032994 SpecPlus_000724 O=C1CC(Oc2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E07 compound treatment 1056510.0 32300.0 0.16 1040100.0 -50600.0 -0.3 759200.0 -111864.84375 -0.640705044774636 -0.4526 -0.624 2060414 SpecPlus_000725 OC(=O)c1nc2cc(Cl)c(Cl)cc2nc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E08 compound treatment 1108960.0 84800.0 0.41 911810.0 -179000.0 -1.06 794150.0 -76914.84375 -0.440529184654387 -0.6295 -0.5144 2060415 SpecPlus_000726 COC(=O)C[C@H]1C(C)(C)C(=O)[C@@H]2CC3=C4C=CO[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E09 compound treatment 730280.0 -294000.0 -1.44 709670.0 -381000.0 -2.27 565470.0 -305594.84375 -1.75029215152988 -3.1479 -0.9827 225 SpecPlus_000727 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E10 compound treatment 1005390.0 -18800.0 -0.09 1085280.0 -5460.0 -0.03 841790.0 -29274.84375 -0.16767144570936 -0.1686 -0.8693 2060416 SpecPlus_000728 Sc1nc2ccccc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E11 compound treatment 404230.0 -620000.0 -3.03 407970.0 -683000.0 -4.06 314240.0 -556824.84375 -3.18921007250299 -5.9342 -0.9914 3054809 SpecPlus_000729 COc1ccc2C(=O)C(Cc3ccc(OC)c(OC(=O)C)c3)COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E12 compound treatment 1020450.0 -3740.0 -0.02 1018160.0 -72600.0 -0.43 710630.0 -160434.84375 -0.91888935167136 -0.7902 -0.7783 2060417 SpecPlus_000730 CC(=C)C1Cc2c(O1)ccc(C(=O)O)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E13 compound treatment 995040.0 -29100.0 -0.14 976870.0 -114000.0 -0.68 724670.0 -146394.84375 -0.838475358077989 -0.9573 -0.8805 2060418 SpecPlus_000731 COc1ccccc1c2cc(=O)c3cccc(OC)c3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E14 compound treatment 1018480.0 -5710.0 -0.03 1101700.0 11000.0 0.07 780700.0 -90364.84375 -0.517563957719261 -0.2773 -0.5308 2060419 SpecPlus_000732 COc1cc(OC)c2C[C@@H](OC(=O)c3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c4cc(OC)c(OC)c(OC)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E15 compound treatment 1106660.0 82500.0 0.4 1025790.0 -65000.0 -0.39 720280.0 -150784.84375 -0.863619049806971 -0.489 -0.4755 3173232 SpecPlus_000733 CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)OC(C)OC(=O)C)COC(=O)N)\c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E16 compound treatment 1076970.0 52800.0 0.26 1056280.0 -34500.0 -0.2 748420.0 -122644.84375 -0.702447413074959 -0.375 -0.4833 2060420 SpecPlus_000734 CC(=O)O[C@@H]1CC2C(C)(C)[C@@H](O)CCC2(C)C3CC[C@@]4(C)[C@@H](OC(=O)C=C4C13C)c5ccoc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E17 compound treatment 890130.0 -134000.0 -0.65 912810.0 -178000.0 -1.06 816100.0 -54964.84375 -0.314810726009481 -1.1708 -0.9121 2060421 SpecPlus_000735 C[C@](O)(CCC1C(=C)C[C@H](O)C2C(C)(C)CCCC12C)C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E18 compound treatment 948110.0 -76100.0 -0.37 971370.0 -119000.0 -0.71 697780.0 -173284.84375 -0.992487629283526 -1.1974 -0.9388 3856 SpecPlus_000736 CNC1(C)C2CCC(C2)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E19 compound treatment 1210490.0 186000.0 0.91 1115840.0 25100.0 0.15 843240.0 -27824.84375 -0.159366581698649 0.5197 0.5552 3173234 SpecPlus_000737 Cn1c(=O)[nH]c(=O)c2nc[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E20 compound treatment 1005410.0 -18800.0 -0.09 1026210.0 -64500.0 -0.38 741090.0 -129974.84375 -0.74442993252221 -0.7043 -0.836 1084508 SpecPlus_000738 COc1ccc2cc3-c4cc(OC)c(OC)cc4CC[n+]3cc2c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E21 compound treatment 783520.0 -241000.0 -1.18 822690.0 -268000.0 -1.59 637200.0 -233864.84375 -1.33945912015862 -2.3725 -0.9922 2060422 SpecPlus_000739 CCOc1ccc(cc1)C(=O)c2cc(O)c(OC)c(OC)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E22 compound treatment 1048170.0 24000.0 0.12 1093030.0 2290.0 0.01 750430.0 -120634.84375 -0.690935153308387 -0.3234 -0.4614 2060423 SpecPlus_000740 COC1=C(Cl)C(=O)C2(Oc3cc(OC)c(Cl)c(C)c3C2=O)C(=C1Cl)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E23 mock treatment 1038100.0 13900.0 0.07 1139150.0 48400.0 0.29 914570.0 43505.15625 0.249175452704137 0.3493 0.9032 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 E24 mock treatment 1065760.0 41600.0 0.2 1175550.0 84800.0 0.5 963880.0 92815.15625 0.531598103992534 0.7154 0.9408 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F01 mock treatment 973020.0 -51200.0 -0.25 1013690.0 -77100.0 -0.46 772590.0 -98474.84375 -0.564013921255033 -0.7345 -0.9558 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F02 mock treatment 1127520.0 103000.0 0.5 1150670.0 59900.0 0.36 828240.0 -42824.84375 -0.245278968016353 0.3556 0.5349 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F03 compound treatment 1246160.0 222000.0 1.08 1009930.0 -80800.0 -0.48 745170.0 -125894.84375 -0.721061763443795 -0.0676 -0.0487 2060424 SpecPlus_000741 C[C@@]12CC[C@@H](O)C[C@H]2CCc3ccccc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F04 compound treatment 875610.0 -149000.0 -0.73 832610.0 -258000.0 -1.53 669680.0 -201384.84375 -1.15343016631869 -1.9713 -0.9603 117 SpecPlus_000742 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F05 compound treatment 1085080.0 60900.0 0.3 926400.0 -164000.0 -0.98 761760.0 -109304.84375 -0.626042664176415 -0.7539 -0.6292 2060425 SpecPlus_000743 COC(=O)[C@@H]1OC(=O)[C@H]2O[C@@]23[C@@]1(C)CCC4[C@@]5(C)CCC(=O)C(C)(C)C5C[C@@H](OC(=O)C)[C@]43C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F06 compound treatment 1199080.0 175000.0 0.85 1230880.0 140000.0 0.83 818100.0 -52964.84375 -0.30335574116712 0.7993 0.6491 1211 SpecPlus_000744 CON 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F07 compound treatment 1354240.0 330000.0 1.61 1283570.0 193000.0 1.15 939210.0 68145.15625 0.390300865962018 1.8184 0.9016 1045087 SpecPlus_000745 Cc1coc2ccccc2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F08 compound treatment 1093080.0 68900.0 0.34 982600.0 -108000.0 -0.64 751960.0 -119104.84375 -0.682172089903981 -0.5708 -0.573 765 SpecPlus_000746 Oc1ccnc(S)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F09 compound treatment 1089530.0 65300.0 0.32 936350.0 -154000.0 -0.92 827560.0 -43504.84375 -0.249173662862755 -0.4896 -0.4879 2060426 SpecPlus_000747 COc1c(O)cccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F10 compound treatment 1020410.0 -3780.0 -0.02 1005220.0 -85500.0 -0.51 637120.0 -233944.84375 -1.33991731955232 -1.0779 -0.752 2546 SpecPlus_000748 COC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F11 compound treatment 1019420.0 -4770.0 -0.02 923520.0 -167000.0 -0.99 689760.0 -181304.84375 -1.03842211850139 -1.1871 -0.8255 2060427 SpecPlus_000749 CO[C@@H]1C[C@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)O[C@H](C)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F12 compound treatment 930910.0 -93300.0 -0.46 844480.0 -246000.0 -1.46 640900.0 -230164.84375 -1.31826739820026 -1.8697 -0.9245 1537011 SpecPlus_000750 CN(C)CCC(c1ccc(Br)cc1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F13 compound treatment 1004090.0 -20100.0 -0.1 1053410.0 -37300.0 -0.22 655780.0 -215284.84375 -1.2330423109731 -0.8967 -0.7136 2060428 SpecPlus_000751 CCOC(=O)C(=O)C1(Oc2cc(OC)cc(OC)c2C(=O)C1c3ccccc3)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F14 compound treatment 950960.0 -73200.0 -0.36 898120.0 -193000.0 -1.15 589480.0 -281584.84375 -1.61277505849734 -1.799 -0.8949 2777 SpecPlus_000752 COc1cc(N)c(Cl)cc1C(=O)NC2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F15 compound treatment 982830.0 -41400.0 -0.2 957600.0 -133000.0 -0.79 683280.0 -187784.84375 -1.07553626939064 -1.1947 -0.8845 2060429 SpecPlus_000753 COC1CC(O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)C(CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)OC(C)C1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F16 compound treatment 955360.0 -68800.0 -0.34 1019570.0 -71200.0 -0.42 711070.0 -159994.84375 -0.916369255006041 -0.9676 -0.9094 3173238 SpecPlus_000754 C[C@@H]1O[C@@H](O[C@H]2CC[C@@]3(C=O)C(CCC4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F17 compound treatment 910800.0 -113000.0 -0.55 972520.0 -118000.0 -0.7 645710.0 -225354.84375 -1.29071815965438 -1.4709 -0.9365 1111461 SpecPlus_000755 CC(=CCOc1c2occc2cc3ccc(=O)oc13)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F18 compound treatment 1025060.0 874.0 0.0 969620.0 -121000.0 -0.72 736770.0 -134294.84375 -0.769172699781709 -0.8575 -0.8137 907149 SpecPlus_000756 CN(C)c1nc(N)c(nc1Cl)C(=O)NC(=N)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F19 compound treatment 683730.0 -340000.0 -1.66 699930.0 -391000.0 -2.32 526980.0 -344084.84375 -1.97074333482111 -3.4399 -0.9909 2060430 SpecPlus_000757 O[C@@H]1O[C@H](COC(=O)CC[N+](=O)[O-])[C@H](OC(=O)CC[N+](=O)[O-])[C@H](OC(=O)CC[N+](=O)[O-])[C@@H]1OC(=O)CC[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F20 compound treatment 559430.0 -465000.0 -2.27 569120.0 -522000.0 -3.1 406140.0 -464924.84375 -2.66285351899653 -4.6393 -0.9921 1950 SpecPlus_000758 Oc1cc2oc(cc(=O)c2c(O)c1O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F21 compound treatment 1106630.0 82400.0 0.4 1109220.0 18500.0 0.11 810030.0 -61034.84375 -0.349576605006045 0.0942 0.1729 3173239 SpecPlus_000759 CC(N/C(=N/C#N)/Nc1ccncc1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F22 compound treatment 1136930.0 113000.0 0.55 1306240.0 215000.0 1.28 829120.0 -41944.84375 -0.240238774685714 0.9192 0.6494 89599 SpecPlus_000760 OC(=O)c1cc(O)c2c(Cl)cc(Cl)cc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F23 mock treatment 940020.0 -84200.0 -0.41 1107070.0 16300.0 0.1 867680.0 -3384.84375 -0.0193866669250043 -0.1925 -0.4552 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 F24 mock treatment 943640.0 -80500.0 -0.39 954140.0 -137000.0 -0.81 833370.0 -37694.84375 -0.215896931895698 -0.8208 -0.8845 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G01 mock treatment 1245870.0 222000.0 1.08 1147780.0 57000.0 0.34 983480.0 112415.15625 0.643856955447667 1.1929 0.9142 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G02 mock treatment 1117290.0 93100.0 0.45 1087260.0 -3480.0 -0.02 876910.0 5845.15625 0.0334780881224893 0.27 0.5914 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G03 compound treatment 1121940.0 97800.0 0.48 1033850.0 -56900.0 -0.34 774830.0 -96234.84375 -0.551184338231589 -0.2378 -0.2958 2060431 SpecPlus_000761 COc1cc2OCOc2cc1c3coc4c5CCC(C)(C)Oc5ccc4c3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G04 compound treatment 921660.0 -103000.0 -0.5 777760.0 -313000.0 -1.86 579680.0 -291384.84375 -1.66890448422491 -2.3273 -0.9128 831758 SpecPlus_000762 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G05 compound treatment 484700.0 -539000.0 -2.64 467750.0 -623000.0 -3.7 360990.0 -510074.84375 -2.92144980181282 -5.3474 -0.9895 2060432 SpecPlus_000763 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccc(O)cc5cc4Cn3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G06 compound treatment 873390.0 -151000.0 -0.74 867480.0 -223000.0 -1.33 610890.0 -260174.84375 -1.49014944575988 -2.0522 -0.9646 1001204 SpecPlus_000764 COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G07 compound treatment 1070160.0 46000.0 0.22 1042420.0 -48300.0 -0.29 793980.0 -77084.84375 -0.441502858365987 -0.2911 -0.5083 3173241 SpecPlus_000765 C[C@@]12CCC3C(CC[C@H]4C[C@@H](CC[C@@]43C)OS(=O)(=O)O)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G08 compound treatment 1047740.0 23600.0 0.12 979730.0 -111000.0 -0.66 758760.0 -112304.84375 -0.643225141439955 -0.686 -0.7386 2060433 SpecPlus_000766 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O[C@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G09 compound treatment 997680.0 -26500.0 -0.13 988580.0 -102000.0 -0.61 759460.0 -111604.84375 -0.639215896745129 -0.7946 -0.8915 3173242 SpecPlus_000767 Nc1nc2cc(Cl)ccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G10 compound treatment 1159080.0 135000.0 0.66 1070190.0 -20600.0 -0.12 745610.0 -125454.84375 -0.718541666778475 -0.1049 -0.1067 1008566 SpecPlus_000768 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G11 compound treatment 770720.0 -253000.0 -1.24 832360.0 -258000.0 -1.54 525760.0 -345304.84375 -1.97773087557495 -2.7439 -0.9821 2101 SpecPlus_000769 Oc1ccc(O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G12 compound treatment 990040.0 -34100.0 -0.17 988130.0 -103000.0 -0.61 691310.0 -179754.84375 -1.02954450524856 -1.043 -0.8632 3173243 SpecPlus_000770 C/C=C\1/C[C@@H](C)[C@](O)(CCO)C(=O)OCC2=CCN3CC[C@@H](OC1=O)C32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G13 compound treatment 68290.0 -956000.0 -4.67 59890.0 -1030000.0 -6.13 48490.0 -822574.84375 -4.71129118343164 -8.9557 -0.9915 2060434 SpecPlus_000771 COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CCc5c(C)c(OC(=O)C)c(OC(=O)C)cc5[C@]4(C)CC[C@@]3(C)C2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G14 compound treatment 1079360.0 55200.0 0.27 1046160.0 -44600.0 -0.27 721920.0 -149144.84375 -0.854225962236235 -0.4906 -0.5252 2060435 SpecPlus_000772 COC(=O)C(OC(=O)C)[C@H]1C(C)(C)C(=O)C[C@@H]2O[C@@]34CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC(C3=C)[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G15 compound treatment 1060000.0 35800.0 0.17 1015870.0 -74900.0 -0.45 692760.0 -178304.84375 -1.02123964123785 -0.7456 -0.6612 2060436 SpecPlus_000773 O=C(CCCCCCCCCCCCC1CCCC1)Nc2ccc(cc2)S(=O)(=O)c3ccc(NC(=O)CCCCCCCCCCCCC4CCCC4)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G16 compound treatment 969020.0 -55200.0 -0.27 1039780.0 -51000.0 -0.3 708030.0 -163034.84375 -0.933780831966428 -0.8697 -0.8543 2060437 SpecPlus_000774 COC(=O)C(O)[C@H]1C(C)(C)[C@H](O)[C@@H]2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G17 compound treatment 1007720.0 -16500.0 -0.08 1022160.0 -68600.0 -0.41 703530.0 -167534.84375 -0.959554547861739 -0.8359 -0.7994 1004889 SpecPlus_000775 CC(=O)Nc1cccc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G18 compound treatment 988900.0 -35300.0 -0.17 1053780.0 -37000.0 -0.22 708860.0 -162204.84375 -0.929027013256849 -0.7628 -0.7863 2060438 SpecPlus_000776 CC(C)(C)NCC(O)COc1cccc2[nH]c(O)nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G19 compound treatment 199330.0 -825000.0 -4.03 117140.0 -974000.0 -5.79 91010.0 -780054.84375 -4.46775820568306 -8.2489 -0.9879 2555 SpecPlus_000777 CCOC(=O)NC1=C(C2CC2)C(=O)C(=C(C3CC3)C1=O)NC(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G20 compound treatment 678940.0 -345000.0 -1.69 636010.0 -455000.0 -2.7 503730.0 -367334.84375 -2.10390753361355 -3.7498 -0.9819 1386109 SpecPlus_000778 Oc1ccc2c(=O)c(O)c(oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G21 compound treatment 863880.0 -160000.0 -0.78 832210.0 -259000.0 -1.54 653690.0 -217374.84375 -1.24501277013336 -2.0586 -0.9675 907181 SpecPlus_000779 NC(=N)NC(=O)c1nc(Cl)c(nc1N)N2CCCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G22 compound treatment 1000330.0 -23900.0 -0.12 1028800.0 -61900.0 -0.37 765510.0 -105554.84375 -0.604564567596989 -0.629 -0.8767 3173362 SpecPlus_000780 C[C@H]1CC[C@@H]2N(C1)C[C@H]3[C@@H]4CC5(O[C@@]6(O)[C@H]7C[C@@H](O)[C@H]5[C@]4(O)[C@@H](O)[C@H](O)[C@@H]3[C@]2(C)O)[C@@]7(C)CC[C@@H]6O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G23 mock treatment 932080.0 -92100.0 -0.45 1032550.0 -58200.0 -0.35 845390.0 -25674.84375 -0.147052472993112 -0.5445 -0.9285 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 G24 mock treatment 1035420.0 11200.0 0.05 1136160.0 45400.0 0.27 883040.0 11975.15625 0.0685876166643241 0.2272 0.8 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H01 mock treatment 1247200.0 223000.0 1.09 1185160.0 94400.0 0.56 970980.0 99915.15625 0.572263300182914 1.2836 0.9489 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H02 mock treatment 1103610.0 79400.0 0.39 1158370.0 67600.0 0.4 856360.0 -14704.84375 -0.0842218811327645 0.4076 0.7212 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H03 compound treatment 806650.0 -218000.0 -1.06 774080.0 -317000.0 -1.88 581760.0 -289304.84375 -1.65699129998886 -2.6575 -0.9755 1402956 SpecPlus_000781 CC(N)C(O)c1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H04 compound treatment 1021210.0 -2980.0 -0.01 921870.0 -169000.0 -1.0 704080.0 -166984.84375 -0.95640442703009 -1.1403 -0.8223 2060439 SpecPlus_000782 COC1=C(OC)C(=O)C(=C(C)C1=O)C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC\C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H05 compound treatment 1130680.0 106000.0 0.52 1080870.0 -9870.0 -0.06 764550.0 -106514.84375 -0.610062960321322 -0.0857 -0.1066 2060440 SpecPlus_000783 COC(=O)C[C@H]1C(C)(C)C(=C2CC3=C4CC(=O)O[C@@H](c5ccoc5)[C@]4(C)CCC3[C@@]1(C)C2=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H06 compound treatment 717290.0 -307000.0 -1.5 680400.0 -410000.0 -2.44 518570.0 -352494.84375 -2.01891154608324 -3.4401 -0.9818 2060441 SpecPlus_000784 OC(=O)c1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H07 compound treatment 956680.0 -67500.0 -0.33 861190.0 -230000.0 -1.37 577760.0 -293304.84375 -1.67990126967358 -1.9484 -0.8899 1897 SpecPlus_000785 NNCc1cccc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H08 compound treatment 144610.0 -880000.0 -4.3 344830.0 -746000.0 -4.44 195600.0 -675464.84375 -3.86871977335182 -7.2756 -0.9984 3173364 SpecPlus_000786 C[C@H]1[C@@]2(C)CCC3C(CCC4C[C@H](CC[C@@]43C)O[C@H]5O[C@H](CO)[C@H](O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O[C@H]7OC[C@@H](O)[C@H](O)[C@H]7O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H]6O)[C@H](O)[C@H]5O)C2O[C@]91CC[C@H](C)CN9 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H09 compound treatment 1087100.0 62900.0 0.31 1041120.0 -49600.0 -0.3 700960.0 -170104.84375 -0.974274203384173 -0.5554 -0.5223 1008060 SpecPlus_000787 C1CCc2nnnn2CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H10 compound treatment 64480.0 -960000.0 -4.69 48450.0 -1040000.0 -6.2 44770.0 -826294.84375 -4.73259745523843 -9.018 -0.991 3197 SpecPlus_000788 Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H11 compound treatment 945680.0 -78500.0 -0.38 982560.0 -108000.0 -0.64 707840.0 -163224.84375 -0.934869055526453 -1.1326 -0.9455 352677 SpecPlus_000789 COc1ccccc1N2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H12 compound treatment 802810.0 -221000.0 -1.08 838260.0 -252000.0 -1.5 541120.0 -329944.84375 -1.88975659198562 -2.5823 -0.9764 2060442 SpecPlus_000790 CCC(N)C(O)c1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H13 compound treatment 1202240.0 178000.0 0.87 1222100.0 131000.0 0.78 849920.0 -21144.84375 -0.121106932325165 0.8833 0.7515 907089 SpecPlus_000791 Cn1c(=O)n(C)c2ncn(CCCl)c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H14 compound treatment 102900.0 -921000.0 -4.5 80930.0 -1010000.0 -6.0 73120.0 -797944.84375 -4.57022304509797 -8.7043 -0.9906 1000697 SpecPlus_000792 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(O[C@@H]4O[C@@H]5CO[C@H](OC5[C@H](O)[C@H]4O)c6cccs6)c7cc8OCOc8cc27 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H15 compound treatment 938590.0 -85600.0 -0.42 1041650.0 -49100.0 -0.29 661310.0 -209754.84375 -1.20136927788397 -1.1036 -0.8456 1464728 SpecPlus_000793 Cn1c(=O)[nH]c2nc[nH]c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H16 compound treatment 913320.0 -111000.0 -0.54 975840.0 -115000.0 -0.68 685290.0 -185774.84375 -1.06402400962407 -1.3215 -0.9607 2060443 SpecPlus_000794 CC(CN1c2ccccc2Sc3cccnc13)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H17 compound treatment 1022020.0 -2170.0 -0.01 1071250.0 -19500.0 -0.12 667840.0 -203224.84375 -1.16396875237366 -0.745 -0.6369 1055442 SpecPlus_000795 Nc1nc(O)c2nc(cnc2n1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H18 compound treatment 924070.0 -100000.0 -0.49 983360.0 -107000.0 -0.64 630130.0 -240934.84375 -1.37995249157637 -1.4478 -0.9064 2547 SpecPlus_000796 CC(=CC1C(C(=O)OCc2cccc(Oc3ccccc3)c2)C1(C)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H19 compound treatment 780560.0 -244000.0 -1.19 768930.0 -322000.0 -1.91 623300.0 -247764.84375 -1.41907126481303 -2.6114 -0.9805 907114 SpecPlus_000797 CN1C2CCC1CC(C2)OC(c3ccccc3)c4ccccc4N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H20 compound treatment 961640.0 -62500.0 -0.31 1034810.0 -55900.0 -0.33 753320.0 -117744.84375 -0.674382700211176 -0.7578 -0.9337 1835 SpecPlus_000798 CCCc1nn(C)c2c(=O)[nH]c(nc12)c3cc(ccc3OCC)S(=O)(=O)N4CCN(C)CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H21 compound treatment 963390.0 -60800.0 -0.3 938970.0 -152000.0 -0.9 616710.0 -254354.84375 -1.45681543986861 -1.5337 -0.8818 2566 SpecPlus_000799 CCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H22 compound treatment 909480.0 -115000.0 -0.56 1023550.0 -67200.0 -0.4 772800.0 -98264.84375 -0.562811147846585 -0.8792 -0.9889 1505499 SpecPlus_000800 OC(=O)c1cc2c(Cl)cc(Cl)cc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H23 mock treatment 993610.0 -30600.0 -0.15 1175210.0 84500.0 0.5 823380.0 -47684.84375 -0.273114581183289 0.0461 0.078 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 H24 mock treatment 929250.0 -94900.0 -0.46 1101160.0 10400.0 0.06 847200.0 -23864.84375 -0.136685711710775 -0.3109 -0.6378 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I01 mock treatment 991810.0 -32400.0 -0.16 1093140.0 2400.0 0.01 808500.0 -62564.84375 -0.35833966841045 -0.29 -0.7398 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I02 mock treatment 1021690.0 -2500.0 -0.01 1140590.0 49800.0 0.3 845380.0 -25684.84375 -0.147109747917323 0.0792 0.2391 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I03 compound treatment 56590.0 -968000.0 -4.73 45700.0 -1050000.0 -6.21 44170.0 -826894.84375 -4.73603395069114 -9.0517 -0.9912 290 SpecPlus_000801 CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)C)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I04 compound treatment 523410.0 -501000.0 -2.45 506770.0 -584000.0 -3.47 413040.0 -458024.84375 -2.62333382129039 -4.9321 -0.9879 2060444 SpecPlus_000802 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c4c(=O)c(O)cccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I05 compound treatment 1087720.0 63500.0 0.31 1088560.0 -2180.0 -0.01 802510.0 -68554.84375 -0.39264734801332 -0.055 -0.1098 2060445 SpecPlus_000803 CC(C)CCCC(C)[C@H]1CCC2C3C=CC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I06 compound treatment 1048800.0 24600.0 0.12 1053570.0 -37200.0 -0.22 772240.0 -98824.84375 -0.566018543602446 -0.385 -0.6215 2060446 SpecPlus_000804 CC1(C)[C@@H](O)C=C[C@@]2(C)C1CC(=O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I07 compound treatment 1198400.0 174000.0 0.85 1046160.0 -44600.0 -0.27 813710.0 -57354.84375 -0.328499432896101 0.1487 0.1565 2294 SpecPlus_000805 CC(=O)NC(C(=O)O)C(C)(C)SN=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I08 compound treatment 1043130.0 18900.0 0.09 1095480.0 4740.0 0.03 733280.0 -137784.84375 -0.789161648331628 -0.3859 -0.4854 3173368 SpecPlus_000806 O=C1CC[C@]2(/C=C/C(=O)NCCCCNCCCNC(=O)\C=C\c3ccc4O[C@@H]2C1)c4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I09 compound treatment 1094120.0 69900.0 0.34 1189640.0 98900.0 0.59 806640.0 -64424.84375 -0.368992804313846 0.3238 0.4184 1865 SpecPlus_000807 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I10 compound treatment 1044570.0 20400.0 0.1 991770.0 -99000.0 -0.59 753710.0 -117354.84375 -0.672148978166915 -0.6704 -0.7457 3684 SpecPlus_000808 OC(=O)C1=CCCNC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I11 compound treatment 1087520.0 63300.0 0.31 889460.0 -201000.0 -1.2 603950.0 -267114.84375 -1.52989824316287 -1.3957 -0.7096 1006104 SpecPlus_000809 Cc1cc(=O)oc2cc(O)cc(O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I12 compound treatment 970730.0 -53500.0 -0.26 934790.0 -156000.0 -0.93 705530.0 -165534.84375 -0.948099563019379 -1.2336 -0.9126 3173369 SpecPlus_000810 CC(C)c1c(OC(=O)C)ccc2c1CCC3C(C)(C)CCC[C@@]32C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I13 compound treatment 1055600.0 31400.0 0.15 1132820.0 42100.0 0.25 682020.0 -189044.84375 -1.08275290984133 -0.392 -0.3495 2060447 SpecPlus_000811 CCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(O)COP(=O)(O)OCC(COC(=O)CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)OC(=O)CCCCCCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I14 compound treatment 1140920.0 117000.0 0.57 1164910.0 74200.0 0.44 748210.0 -122854.84375 -0.703650186483407 0.1777 0.1764 2060448 SpecPlus_000812 COc1ccc2[C@H](O)[C@H](Cc3ccc(OC)c(OC)c3)COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I15 compound treatment 940920.0 -83300.0 -0.41 1025510.0 -65200.0 -0.39 773660.0 -97404.84375 -0.55788550436437 -0.7809 -0.9861 2060449 SpecPlus_000813 CCCCCCCCCCCCCC1CC(CO)OC(C)(C)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I16 compound treatment 975780.0 -48400.0 -0.24 1088820.0 -1920.0 -0.01 703010.0 -168054.84375 -0.962532843920753 -0.6989 -0.705 470 SpecPlus_000814 OC(=O)CCCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I17 compound treatment 904900.0 -119000.0 -0.58 932980.0 -158000.0 -0.94 624050.0 -247014.84375 -1.41477564549714 -1.6949 -0.9444 2060450 SpecPlus_000815 COc1ccc(cc1)c2coc3cc(OC)c(OC)cc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I18 compound treatment 1007910.0 -16300.0 -0.08 995840.0 -94900.0 -0.56 722180.0 -148884.84375 -0.852736814206728 -0.8641 -0.8424 1024489 SpecPlus_000816 Cc1cc(O)cc(=O)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I19 compound treatment 175910.0 -848000.0 -4.14 180080.0 -911000.0 -5.42 138420.0 -732644.84375 -4.1962177899949 -7.9421 -0.9919 1001621 SpecPlus_000817 Oc1cc(cc(O)c1O)C(=O)Oc2cc(cc(O)c2O)C(=O)OC[C@H]3O[C@H](OC(=O)c4cc(O)c(O)c(OC(=O)c5cc(O)c(O)c(O)c5)c4)[C@H](OC(=O)c6cc(O)c(O)c(OC(=O)c7cc(O)c(O)c(O)c7)c6)[C@@H](OC(=O)c8cc(O)c(O)c(OC(=O)c9cc(O)c(O)c(O)c9)c8)[C@@H]3OC(=O)c%10cc(O)c(O)c(OC(=O)c%11cc(O)c(O)c(O)c%11)c%10 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I20 compound treatment 1044070.0 19900.0 0.1 1096800.0 6060.0 0.04 765830.0 -105234.84375 -0.602731770022211 -0.2711 -0.4433 2060451 SpecPlus_000818 CC(C)(O)CC[C@@H](O)[C@](C)(O)C1CC[C@@]2(O)C3=CC(=O)C4C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I21 compound treatment 780160.0 -244000.0 -1.19 823260.0 -267000.0 -1.59 570560.0 -300504.84375 -1.72113921510607 -2.6004 -0.989 3173490 SpecPlus_000819 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)cc(O)c4c3=O)c6ccc(O)cc6)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I22 compound treatment 906400.0 -118000.0 -0.58 1212960.0 122000.0 0.73 698560.0 -172504.84375 -0.988020185195005 -0.4831 -0.3566 1754 SpecPlus_000820 CCCN[C@H]1CCc2nc(N)sc2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I23 mock treatment 1007710.0 -16500.0 -0.08 1292860.0 202000.0 1.2 891200.0 20135.15625 0.115323954821155 0.714 0.5901 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 I24 mock treatment 1047040.0 22900.0 0.11 1131930.0 41200.0 0.24 862150.0 -8914.84375 -0.051059700014131 0.1764 0.6438 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J01 mock treatment 1113390.0 89200.0 0.44 1224170.0 133000.0 0.79 1005490.0 134425.15625 0.769919063637844 1.1542 0.9713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J02 mock treatment 1074270.0 50100.0 0.24 1072640.0 -18100.0 -0.11 819290.0 -51774.84375 -0.296540025185916 -0.0921 -0.2306 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J03 compound treatment 1329810.0 306000.0 1.49 1248120.0 157000.0 0.94 936880.0 65815.15625 0.376955808620668 1.6201 0.899 2060452 SpecPlus_000821 CC1(C)O[C@@H]2C[C@](O)(C[C@@H](O)[C@@H]2O1)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J04 compound treatment 1292400.0 268000.0 1.31 1175840.0 85100.0 0.51 978240.0 107175.15625 0.613844895160682 1.4032 0.9153 2548 SpecPlus_000822 CCCCC[C@](C)(C/C=C/C=C/C(=O)OC(C)C)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J05 compound treatment 812810.0 -211000.0 -1.03 753960.0 -337000.0 -2.0 616400.0 -254664.84375 -1.45859096251917 -2.5946 -0.9666 4362 SpecPlus_000823 CN1CCN(CC1)C2=Nc3ccccc3Oc4ccc(Cl)cc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J06 compound treatment 52170.0 -972000.0 -4.75 42080.0 -1050000.0 -6.24 38890.0 -832174.84375 -4.76627511067497 -9.094 -0.9913 2060453 SpecPlus_000824 Clc1c(Cl)c(C#N)c(Cl)c(C#N)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J07 compound treatment 616690.0 -407000.0 -1.99 726460.0 -364000.0 -2.17 447700.0 -423364.84375 -2.42481893397228 -3.8001 -0.9967 2830 SpecPlus_000825 Clc1ccc2n(C3CCN(CCCn4c(=O)[nH]c5ccccc45)CC3)c(=O)[nH]c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J08 compound treatment 492480.0 -532000.0 -2.6 511380.0 -579000.0 -3.45 355750.0 -515314.84375 -2.9514618620998 -5.193 -0.9933 2060454 SpecPlus_000826 Oc1cc(O)c2c(=O)cc(oc2c1)c3cc(O)c(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J09 compound treatment 344000.0 -680000.0 -3.32 328730.0 -762000.0 -4.53 260050.0 -611014.84375 -3.49958288680675 -6.5553 -0.9902 3173492 SpecPlus_000827 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(O)ccc3-c2c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J10 compound treatment 795460.0 -229000.0 -1.12 943260.0 -147000.0 -0.88 594370.0 -276694.84375 -1.58476762055777 -2.0665 -0.971 3173493 SpecPlus_000828 CC1=C2CCC3C4CCC(=O)[C@@]4(C)CCC3[C@@]2(C)CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J11 compound treatment 765180.0 -259000.0 -1.27 969850.0 -121000.0 -0.72 547840.0 -323224.84375 -1.85126784291529 -2.2145 -0.9404 1429 SpecPlus_000829 CCCCOC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J12 compound treatment 962080.0 -62100.0 -0.3 993120.0 -97600.0 -0.58 671330.0 -199734.84375 -1.14397980382374 -1.1708 -0.8882 2060455 SpecPlus_000830 NC(=N)Nc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J13 compound treatment 302460.0 -722000.0 -3.53 258590.0 -832000.0 -4.95 227460.0 -643604.84375 -3.68624186481301 -7.0211 -0.9879 1036721 SpecPlus_000831 Oc1c(oc2ccccc2c1=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J14 compound treatment 1142580.0 118000.0 0.58 1288730.0 198000.0 1.18 774280.0 -96784.84375 -0.554334459063238 0.6937 0.4871 1008178 SpecPlus_000832 COc1cc(C)c(C(=O)Oc2cc(C)c(C(=O)O)c(O)c2C)c(OC)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J15 compound treatment 1163920.0 140000.0 0.68 1071590.0 -19200.0 -0.11 719010.0 -152054.84375 -0.870892965181869 -0.1744 -0.1568 1606 SpecPlus_000833 NS(=O)(=O)c1cc2c(NC(CSCC=C)NS2(=O)=O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J16 compound treatment 1015590.0 -8600.0 -0.04 1182680.0 91900.0 0.55 682420.0 -188644.84375 -1.08046191287285 -0.3324 -0.2743 2060456 SpecPlus_000834 C[C@@H]1CC(Cl)CC[C@H]1C(=O)OC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J17 compound treatment 990150.0 -34000.0 -0.17 971360.0 -119000.0 -0.71 669160.0 -201904.84375 -1.1564084623777 -1.1735 -0.8584 2060457 SpecPlus_000835 COc1cc(O)c2c(=O)cc(oc2c1)c3ccc(O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J18 compound treatment 987430.0 -36800.0 -0.18 809400.0 -281000.0 -1.67 630520.0 -240544.84375 -1.37771876953211 -1.865 -0.8576 907120 SpecPlus_000836 CC(N)C(=O)OC(C)(C)Cc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J19 compound treatment 1028810.0 4620.0 0.02 1275230.0 184000.0 1.1 719320.0 -151744.84375 -0.869117442531304 0.1447 0.1033 2060458 SpecPlus_000837 CC(=O)Oc1cccc(C(=O)O)c1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J20 compound treatment 492660.0 -532000.0 -2.6 564000.0 -527000.0 -3.13 323940.0 -547124.84375 -3.13365339601754 -5.117 -0.9964 2060459 SpecPlus_000838 OC[C@H]1OC2[C@@H](Oc3nc(=N)ccn23)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J21 compound treatment 966340.0 -57800.0 -0.28 879710.0 -211000.0 -1.25 718290.0 -152774.84375 -0.875016759725119 -1.3929 -0.8953 2060460 SpecPlus_000839 NC1=NCC(O1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J22 compound treatment 766850.0 -257000.0 -1.26 695680.0 -395000.0 -2.35 518990.0 -352074.84375 -2.01650599926634 -3.2465 -0.9715 3173494 SpecPlus_000840 COC1CC(CC(C)C2CC(=O)C(C)/C=C(\C)/C(O)C(OC)C(=O)C(C)CC(C)/C=C/C=C/C=C(\C)/C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC)CCC1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J23 mock treatment 1065550.0 41400.0 0.2 1139760.0 49000.0 0.29 890820.0 19755.15625 0.113147507701106 0.3503 0.9409 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 J24 mock treatment 1076510.0 52300.0 0.26 1120550.0 29800.0 0.18 839420.0 -31644.84375 -0.181245602747558 0.1453 0.4036 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K01 mock treatment 1196900.0 173000.0 0.84 1233280.0 143000.0 0.85 1042950.0 171885.15625 0.984470929735255 1.545 0.9973 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K02 mock treatment 1115140.0 91000.0 0.44 1298410.0 208000.0 1.23 849560.0 -21504.84375 -0.12316882959679 0.8984 0.6816 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K03 compound treatment 547530.0 -477000.0 -2.33 523250.0 -567000.0 -3.37 419170.0 -451894.84375 -2.58822429274855 -4.7872 -0.9873 2060461 SpecPlus_000841 COc1ccc(C2COc3c(OC)c(O)ccc3C2)c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K04 compound treatment 965120.0 -59100.0 -0.29 1156610.0 65900.0 0.39 704730.0 -166334.84375 -0.952681556956323 -0.4905 -0.4585 3474304 SpecPlus_000842 COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K05 compound treatment 1063680.0 39500.0 0.19 1223780.0 133000.0 0.79 819520.0 -51544.84375 -0.295222701929044 0.3977 0.4592 366 SpecPlus_000843 OC(=O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K06 compound treatment 1006470.0 -17700.0 -0.09 968130.0 -123000.0 -0.73 725970.0 -145094.84375 -0.831029617930455 -0.9507 -0.8573 2060462 SpecPlus_000844 C[C@H]1[C@@H]2[C@@H](O)C[C@@]3(C)C=CC(=O)C(=C3[C@@]2(C)OC1=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K07 compound treatment 54300.0 -970000.0 -4.74 52750.0 -1040000.0 -6.17 40670.0 -830394.84375 -4.75608017416527 -9.0455 -0.9918 3173495 SpecPlus_000845 COC(=O)C[C@H]1[C@@]2(C)C(OC3CC(C(=C32)C)c4ccoc4)[C@@H]5OC(=O)[C@]6(C)C=CC(=O)[C@@]1(C)C56 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K08 compound treatment 914730.0 -109000.0 -0.53 1004760.0 -86000.0 -0.51 663250.0 -207814.84375 -1.19025794258688 -1.2911 -0.9213 2060463 SpecPlus_000846 COc1ccc(cc1)c2coc3c(OC)c(OC)cc(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K09 compound treatment 1087260.0 63100.0 0.31 1110570.0 19800.0 0.12 713600.0 -157464.84375 -0.901878699180454 -0.2747 -0.286 2060464 SpecPlus_000847 CC(C)CCCC(C)[C@H]1CCC2C3C(CC[C@]12C)[C@@]4(C)CC[C@H](O)C[C@@H]4CC3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K10 compound treatment 991530.0 -32700.0 -0.16 1130120.0 39400.0 0.23 706210.0 -164854.84375 -0.944204868172976 -0.5021 -0.5093 2060465 SpecPlus_000848 CC(=O)O[C@H]1CC[C@@]2(C)C(CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K11 compound treatment 24830.0 -999000.0 -4.88 28410.0 -1060000.0 -6.32 18490.0 -852574.84375 -4.88311595606705 -9.2855 -0.9921 3055171 SpecPlus_000849 COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CCc5c(C)c(O)c(O)cc5[C@]4(C)CC[C@@]3(C)C2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K12 compound treatment 80280.0 -944000.0 -4.61 58370.0 -1030000.0 -6.14 40510.0 -830554.84375 -4.75699657295266 -8.9534 -0.9913 1010201 SpecPlus_000850 ClC1=C(Cl)C(=O)C(=C(Cl)C1=O)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K13 compound treatment 1020930.0 -3260.0 -0.02 1148960.0 58200.0 0.35 756160.0 -114904.84375 -0.658116621735024 -0.1893 -0.2545 2060466 SpecPlus_000851 OC(=O)Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K14 compound treatment 699090.0 -325000.0 -1.59 803580.0 -287000.0 -1.71 472480.0 -398584.84375 -2.28289167177543 -3.221 -0.987 2060467 SpecPlus_000852 COc1ccc2C(=O)/C(=C\c3ccc(OC)c(OC)c3)/COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K15 compound treatment 933820.0 -90400.0 -0.44 1063680.0 -27100.0 -0.16 658990.0 -212074.84375 -1.21465706030111 -1.0491 -0.8055 2060468 SpecPlus_000853 CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K16 compound treatment 938030.0 -86200.0 -0.42 1088160.0 -2580.0 -0.02 677920.0 -193144.84375 -1.10623562876817 -0.8906 -0.7524 840551 SpecPlus_000854 NCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K17 compound treatment 509600.0 -515000.0 -2.51 506770.0 -584000.0 -3.47 350970.0 -520094.84375 -2.97883927587304 -5.1763 -0.9915 3055207 SpecPlus_000855 COc1cc(O)cc(/C=C/c2ccccc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K18 compound treatment 1007570.0 -16600.0 -0.08 1020840.0 -69900.0 -0.42 690200.0 -180864.84375 -1.03590202183607 -0.8849 -0.7907 2060469 SpecPlus_000856 C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)C)C3(C)C[C@H](O)C2C4(C)C=CC(=O)C=C14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K19 compound treatment 1151130.0 127000.0 0.62 1274280.0 184000.0 1.09 836020.0 -35044.84375 -0.20071907697957 0.8723 0.6862 3055209 SpecPlus_000857 COc1cc(C(=O)O)c2Oc3c(C(O)O)c(O)cc(C)c3C(=O)Oc2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K20 compound treatment 887930.0 -136000.0 -0.67 1008990.0 -81800.0 -0.49 671220.0 -199844.84375 -1.14460982799007 -1.3259 -0.94 1015899 SpecPlus_000858 NCC(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K21 compound treatment 1023710.0 -476.0 0.0 1015100.0 -75600.0 -0.45 658420.0 -212644.84375 -1.21792173098118 -0.9642 -0.7426 2060470 SpecPlus_000859 CC1CCC=C2C(CC(CC12C)C(=C)C)OC(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K22 compound treatment 923540.0 -101000.0 -0.49 905180.0 -186000.0 -1.1 760160.0 -110904.84375 -0.635206652050303 -1.2877 -0.9435 1044412 SpecPlus_000860 Oc1cc2ccccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K23 mock treatment 966490.0 -57700.0 -0.28 1116760.0 26000.0 0.15 845200.0 -25864.84375 -0.148140696553136 -0.1589 -0.4489 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 K24 mock treatment 1075220.0 51000.0 0.25 1158140.0 67400.0 0.4 936600.0 65535.15625 0.375352110742737 0.5921 0.9817 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L01 mock treatment 1255040.0 231000.0 1.13 1099270.0 8530.0 0.05 1028220.0 157155.15625 0.90010496637127 1.2002 0.8312 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L02 mock treatment 1073600.0 49400.0 0.24 1173460.0 82700.0 0.49 932450.0 61385.15625 0.351583017194839 0.6264 0.9621 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L03 compound treatment 49530.0 -975000.0 -4.76 43890.0 -1050000.0 -6.23 37600.0 -833464.84375 -4.77366357589829 -9.0995 -0.9916 1009556 SpecPlus_000861 Nc1c2ccccc2nc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L04 compound treatment 988370.0 -35800.0 -0.17 1195430.0 105000.0 0.62 735260.0 -135804.84375 -0.777821213337691 -0.1907 -0.1885 2060471 SpecPlus_000862 C[C@H]1[C@H]2[C@H](OC1=O)[C@@H]3C(=CC(=O)C3=C(C)C[C@@H]2O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L05 compound treatment 1133820.0 110000.0 0.54 1182890.0 92100.0 0.55 741530.0 -129534.84375 -0.741909835856891 0.1973 0.185 2060472 SpecPlus_000863 C[C@@]12CCC3C(C=CC4=CC(=O)CC[C@]34C)C2CC[C@@]1(O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L06 compound treatment 621660.0 -403000.0 -1.97 605860.0 -485000.0 -2.88 441520.0 -429544.84375 -2.46021483713517 -4.2206 -0.9884 593 SpecPlus_000864 Oc1ccc2ccc(=O)oc2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L07 compound treatment 942370.0 -81800.0 -0.4 1134500.0 43800.0 0.26 713850.0 -157214.84375 -0.900446826075159 -0.6004 -0.5892 1009258 SpecPlus_000865 O=C1NC(=O)C(=O)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L08 compound treatment 213280.0 -811000.0 -3.96 192540.0 -898000.0 -5.34 155550.0 -715514.84375 -4.09810584482008 -7.7372 -0.9905 2060473 SpecPlus_000866 C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@](C)(O)CC[C@@H]1[C@@]23O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L09 compound treatment 958040.0 -66100.0 -0.32 1016260.0 -74500.0 -0.44 645470.0 -225594.84375 -1.29209275783546 -1.1883 -0.8466 3055218 SpecPlus_000867 OCC(O)[C@H]1OC(=O)C(=C1O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L10 compound treatment 952810.0 -71400.0 -0.35 1096590.0 5850.0 0.03 657440.0 -213624.84375 -1.22353467355394 -0.8877 -0.6974 1001314 SpecPlus_000868 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)[C@@H]4N[C@@H](COCCOC)O[C@H]([C@H]4C)[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L11 compound treatment 86050.0 -938000.0 -4.58 58000.0 -1030000.0 -6.14 60740.0 -810324.84375 -4.64112940127218 -8.8715 -0.9902 1473 SpecPlus_000869 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L12 compound treatment 954440.0 -69700.0 -0.34 1264060.0 173000.0 1.03 717650.0 -153414.84375 -0.878682354874675 -0.109 -0.078 3474312 SpecPlus_000870 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L13 compound treatment 1018470.0 -5720.0 -0.03 1207870.0 117000.0 0.7 720570.0 -150494.84375 -0.861958077004828 -0.1116 -0.1007 1000219 SpecPlus_000871 N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L14 compound treatment 766410.0 -258000.0 -1.26 760650.0 -330000.0 -1.96 536840.0 -334224.84375 -1.91427025954827 -2.9656 -0.9829 2060474 SpecPlus_000872 O[C@@H]1Cc2c(O)cc(O)c([C@@H]3[C@@H](O)[C@H](Oc4c([C@@H]5[C@@H](O)[C@H](Oc6cc(O)cc(O)c56)c7cc(O)c(O)c(O)c7)c(O)cc(O)c34)c8cc(O)c(O)c(O)c8)c2O[C@@H]1c9cc(O)c(O)c(O)c9 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L15 compound treatment 935970.0 -88200.0 -0.43 878780.0 -212000.0 -1.26 659280.0 -211784.84375 -1.21299608749896 -1.6769 -0.9308 2060475 SpecPlus_000873 COc1cc(OC)c2C(=O)CC(Oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L16 compound treatment 884440.0 -140000.0 -0.68 970020.0 -121000.0 -0.72 635450.0 -235614.84375 -1.34948223189569 -1.5878 -0.9484 3474314 SpecPlus_000874 CN1CCCCC1C(=O)Nc2c(C)cccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L17 compound treatment 697230.0 -327000.0 -1.6 714450.0 -376000.0 -2.24 508360.0 -362704.84375 -2.07738924370349 -3.4136 -0.9906 2552 SpecPlus_000875 OC[C@H]1O[C@H](C(O)[C@H]1O)n2c(F)cc(=O)[nH]c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L18 compound treatment 783430.0 -241000.0 -1.18 937640.0 -153000.0 -0.91 590560.0 -280504.84375 -1.60658936668247 -2.1323 -0.9739 2060476 SpecPlus_000876 C[C@H]1[C@@H]2CCC(=C3[C@@H]([C@H]2OC1=O)C(=CC3=O)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L19 compound treatment 1022680.0 -1510.0 -0.01 1395110.0 304000.0 1.81 758470.0 -112594.84375 -0.644886114242097 0.6684 0.3479 2060477 SpecPlus_000877 CC(C)CCCC(C)C1CCC2C3=CC[C@H]4C[C@@H](O)CCC4(C)C3CCC12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L20 compound treatment 726040.0 -298000.0 -1.46 931560.0 -159000.0 -0.95 557350.0 -313714.84375 -1.79679938998987 -2.4249 -0.9702 1089854 SpecPlus_000878 Cc1ncc(CNC(=O)N(CCCl)N=O)c(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L21 compound treatment 928530.0 -95700.0 -0.47 1006680.0 -84100.0 -0.5 763250.0 -107814.84375 -0.617508700468856 -0.9149 -0.9926 2060478 SpecPlus_000879 CNc1ccc(cc1)C(=O)CC(O)CCC(C)C2OC(=O)CC(O)CC(=O)CC(O)CC(O)CC(O)CC(O)CC3(O)CC(O)C(C(CC(O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/C2C)O3)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L22 compound treatment 513760.0 -510000.0 -2.49 529490.0 -561000.0 -3.34 484480.0 -386584.84375 -2.21416176272127 -4.6451 -0.9845 2060479 SpecPlus_000880 COC(=O)c1c(C)cc(OC(=O)c2c(C)cc(O)c(CO)c2O)c(C)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L23 mock treatment 964530.0 -59700.0 -0.29 1032320.0 -58400.0 -0.35 848070.0 -22994.84375 -0.131702793304349 -0.4449 -0.9421 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 L24 mock treatment 973410.0 -50800.0 -0.25 973280.0 -117000.0 -0.7 819680.0 -51384.84375 -0.294306303141655 -0.7164 -0.8983 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M01 mock treatment 1138750.0 115000.0 0.56 1127690.0 36900.0 0.22 1019540.0 148475.15625 0.850390332155426 0.941 0.9035 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M02 mock treatment 1072180.0 48000.0 0.23 1132480.0 41700.0 0.25 956070.0 85005.15625 0.486866388183116 0.5598 0.9413 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M03 compound treatment 719360.0 -305000.0 -1.49 781780.0 -309000.0 -1.84 555630.0 -315434.84375 -1.8066506769543 -2.9637 -0.9958 2060480 SpecPlus_000881 Oc1ccc(cc1)C2CC(=O)c3ccccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M04 compound treatment 760090.0 -264000.0 -1.29 726080.0 -365000.0 -2.17 603220.0 -267844.84375 -1.53407931263033 -2.8826 -0.9762 3173624 SpecPlus_000882 CC1CCC2=C1C[C@@H](CC[C@@H]2C)C(C)(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M05 compound treatment 910810.0 -113000.0 -0.55 1038100.0 -52600.0 -0.31 666170.0 -204894.84375 -1.17353366471703 -1.1781 -0.8825 3173625 SpecPlus_000883 Nc1nc2n(cnc2c(=O)[nH]1)C3C[C@H](O)[C@@H](CO)O3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M06 compound treatment 1113880.0 89700.0 0.44 1171640.0 80900.0 0.48 812130.0 -58934.84375 -0.337548870921566 0.3359 0.4582 1002856 SpecPlus_000884 CCC(C(=O)N)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M07 compound treatment 1026580.0 2390.0 0.01 1094320.0 3580.0 0.02 830090.0 -40974.84375 -0.234683107037169 -0.1165 -0.4936 3173626 SpecPlus_000885 CC(C)C(C)/C=C/C(C)C1CCC2C3=CC=C4C(C)(C)C(CCC4(C)C3CCC12C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M08 compound treatment 56340.0 -968000.0 -4.73 44160.0 -1050000.0 -6.22 37830.0 -833234.84375 -4.77234625264142 -9.0786 -0.9913 3055280 SpecPlus_000886 CCCCCCc1ccc(O)cc1O.Nc1c2ccccc2nc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M09 compound treatment 984280.0 -39900.0 -0.19 1134750.0 44000.0 0.26 792590.0 -78474.84375 -0.449464072831428 -0.221 -0.3978 3173627 SpecPlus_000887 CCCCCC(O)C1C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)/C(=C/C=C/C=C/C=C/C=C/C(O)C(C)OC1=O)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M10 compound treatment 872910.0 -151000.0 -0.74 1138680.0 47900.0 0.29 679000.0 -192064.84375 -1.10004993695329 -0.8972 -0.6619 2060481 SpecPlus_000888 COc1ccc([C@@H]2COc3c(OC)c(O)ccc3C2)c(OC)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M11 compound treatment 105940.0 -918000.0 -4.49 88240.0 -1000000.0 -5.96 135040.0 -736024.84375 -4.21557671437849 -8.4659 -0.9879 2060482 SpecPlus_000889 CC(C)c1cc2CCC3C(C)(C)CCC[C@]3(C(=O)O)c2c(O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M12 compound treatment 926200.0 -98000.0 -0.48 1041070.0 -49700.0 -0.3 756640.0 -114424.84375 -0.655367425372857 -0.8253 -0.9556 2060483 SpecPlus_000890 CC(=O)N[C@@H](CC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M13 compound treatment 1042100.0 17900.0 0.09 1194950.0 104000.0 0.62 797640.0 -73424.84375 -0.420540236104468 0.1655 0.2195 3173628 SpecPlus_000891 CN1C(C)(C)CCCC1(C)C.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M14 compound treatment 737300.0 -287000.0 -1.4 829860.0 -261000.0 -1.55 553730.0 -317334.84375 -1.81753291255454 -2.7543 -0.9942 1001523 SpecPlus_000892 Nc1ccc(C(=O)Oc2ccccc2)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M15 compound treatment 694430.0 -330000.0 -1.61 769510.0 -321000.0 -1.91 510820.0 -360244.84375 -2.06329961234738 -3.2243 -0.995 2060485 SpecPlus_000893 COc1cc2OCC3Oc4c5CCC(C)(C)Oc5cc(OC)c4C(=O)C3c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M16 compound treatment 956350.0 -67800.0 -0.33 1296850.0 206000.0 1.23 811380.0 -59684.84375 -0.341844490237451 0.3189 0.2425 2060486 SpecPlus_000894 CC(=O)Oc1ccccc1C(=O)Oc2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M17 compound treatment 58950.0 -965000.0 -4.72 55360.0 -1040000.0 -6.16 44800.0 -826264.84375 -4.73242563046579 -9.0098 -0.9917 1000094 SpecPlus_000895 CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M18 compound treatment 856850.0 -167000.0 -0.82 901090.0 -190000.0 -1.13 699360.0 -171704.84375 -0.983438191258061 -1.6909 -0.9917 1734308 SpecPlus_000896 Oc1cc(O)c2C(=O)C[C@H](Oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M19 compound treatment 965880.0 -58300.0 -0.28 1038080.0 -52700.0 -0.31 757650.0 -113414.84375 -0.649582658027465 -0.7203 -0.929 1002855 SpecPlus_000897 CCC(C(=O)O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M20 compound treatment 895690.0 -128000.0 -0.63 1103050.0 12300.0 0.07 704480.0 -166584.84375 -0.954113430061618 -0.8711 -0.7611 3173630 SpecPlus_000898 C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CCC(OC(=O)C)C(C)(C)C5CC[C@]43C)C2C1C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M21 compound treatment 983060.0 -41100.0 -0.2 1281050.0 190000.0 1.13 846810.0 -24254.84375 -0.138919433755036 0.4572 0.3949 1091345 SpecPlus_000899 Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O)cnc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M22 compound treatment 122050.0 -902000.0 -4.41 94000.0 -997000.0 -5.93 95800.0 -775264.84375 -4.4403235169856 -8.5305 -0.9898 907273 SpecPlus_000900 Fc1ccc(cc1)C(OCCN2CCN(CCCc3ccccc3)CC2)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M23 mock treatment 950580.0 -73600.0 -0.36 1051170.0 -39600.0 -0.24 865060.0 -6004.84375 -0.0343926970684965 -0.3633 -0.8427 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 M24 mock treatment 903040.0 -121000.0 -0.59 1025030.0 -65700.0 -0.39 856870.0 -14194.84375 -0.0813008599979626 -0.6143 -0.8605 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N01 mock treatment 1110440.0 86300.0 0.42 1229280.0 139000.0 0.82 903130.0 32065.15625 0.183652939405835 0.825 0.8745 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N02 mock treatment 947930.0 -76300.0 -0.37 1089860.0 -880.0 -0.01 862260.0 -8804.84375 -0.0504296758478011 -0.2472 -0.6575 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N03 compound treatment 958320.0 -65900.0 -0.32 1003270.0 -87500.0 -0.52 757040.0 -114024.84375 -0.653076428404385 -0.8632 -0.9647 3055336 SpecPlus_000901 Oc1ccc2sc(=O)oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N04 compound treatment 1116320.0 92100.0 0.45 1175540.0 84800.0 0.5 804720.0 -66344.84375 -0.379989589762512 0.3316 0.4277 1765 SpecPlus_000902 CC1(C)NC(=O)N(C1=O)c2ccc([N+](=O)[O-])c(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N05 compound treatment 919360.0 -105000.0 -0.51 1031970.0 -58800.0 -0.35 772510.0 -98554.84375 -0.564472120648727 -0.8234 -0.982 3173631 SpecPlus_000903 Oc1c(oc2ccc3occc3c2c1=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N06 compound treatment 627520.0 -397000.0 -1.94 741120.0 -350000.0 -2.08 501280.0 -369784.84375 -2.11793989004544 -3.5421 -0.9993 1013144 SpecPlus_000904 O=C1OC(=O)C2C3CCC(O3)C21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N07 compound treatment 1172500.0 148000.0 0.72 1286290.0 196000.0 1.16 837620.0 -33444.84375 -0.191555089105682 0.9791 0.7077 1002775 SpecPlus_000905 Cc1cccc(C(=O)O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N08 compound treatment 1216340.0 192000.0 0.94 1095910.0 5170.0 0.03 754270.0 -116794.84375 -0.668941582411054 0.1736 0.1505 2060487 SpecPlus_000906 OC(=O)C1CC(CN2CCCCC12)[C@H]3CCCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N09 compound treatment 1232730.0 209000.0 1.02 1243310.0 153000.0 0.91 813200.0 -57864.84375 -0.331420454030903 0.9207 0.6558 3173633 SpecPlus_000907 CC1=C(N2[C@H](SC1)[C@H](NC(=O)C(N)c3ccccc3)C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N10 compound treatment 1016000.0 -8190.0 -0.04 1221970.0 131000.0 0.78 747440.0 -123624.84375 -0.708060355647715 0.0187 0.0177 1307902 SpecPlus_000908 CN1CCCCC1c2ccc(nc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N11 compound treatment 1047010.0 22800.0 0.11 1181330.0 90600.0 0.54 831710.0 -39354.84375 -0.225404569314857 0.2453 0.4125 2060488 SpecPlus_000909 CC(=CCC[C@@](C)(O)C=C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N12 compound treatment 1040540.0 16400.0 0.08 1122880.0 32100.0 0.19 769920.0 -101144.84375 -0.579306326019584 -0.178 -0.2893 1216977 SpecPlus_000910 CC1(C)Oc2ccc3ccc(=O)oc3c2CC1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N13 compound treatment 758470.0 -266000.0 -1.3 777640.0 -313000.0 -1.86 576880.0 -294184.84375 -1.68494146300422 -2.7973 -0.9895 1661997 SpecPlus_000911 CC12CCC3C(CCc4cc(OC(=O)c5ccccc5)ccc34)C2CCC1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N14 compound treatment 909480.0 -115000.0 -0.56 957860.0 -133000.0 -0.79 659850.0 -211214.84375 -1.20973141681889 -1.4782 -0.9538 2060489 SpecPlus_000912 C/C=C(/C)\C(=O)O[C@@H]1Cc2c(OC1(C)C)ccc3ccc(=O)oc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N15 compound treatment 663890.0 -360000.0 -1.76 751420.0 -339000.0 -2.02 514820.0 -356244.84375 -2.04038964266266 -3.3593 -0.9979 1554635 SpecPlus_000913 COc1cc(OC)c2c(=O)cc(oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N16 compound treatment 951520.0 -72700.0 -0.36 1150180.0 59400.0 0.35 819230.0 -51834.84375 -0.296883674731187 -0.1723 -0.2959 2060490 SpecPlus_000914 C/C=C(\C)/C(=O)O[C@H]1[C@@H](OC(=O)C)C(C)(C)Oc2ccc3ccc(=O)oc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N17 compound treatment 927520.0 -96700.0 -0.47 1204410.0 114000.0 0.68 757140.0 -113924.84375 -0.652503679162267 -0.2591 -0.2464 2562 SpecPlus_000915 OC(=O)CF 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N18 compound treatment 868580.0 -156000.0 -0.76 1044920.0 -45800.0 -0.27 725470.0 -145594.84375 -0.833893364141045 -1.0777 -0.9284 2060491 SpecPlus_000916 CC(C)CC(=O)O[C@@H]1[C@H](OC(=O)C)c2c(OC1(C)C)ccc3ccc(=O)oc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N19 compound treatment 900040.0 -124000.0 -0.61 993170.0 -97600.0 -0.58 697810.0 -173254.84375 -0.99231580451089 -1.2581 -0.968 1000807 SpecPlus_000917 CN1CCN(CC1)C(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N20 compound treatment 921710.0 -102000.0 -0.5 1145050.0 54300.0 0.32 736800.0 -134264.84375 -0.769000875009073 -0.5466 -0.5619 3055383 SpecPlus_000918 CC(C)(O)[C@@H]1Cc2cc3ccc(=O)oc3cc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N21 compound treatment 884320.0 -140000.0 -0.68 955050.0 -136000.0 -0.81 793150.0 -77914.84375 -0.446256677075567 -1.118 -0.9742 1003514 SpecPlus_000919 COc1cc(cc(OC)c1OC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N22 compound treatment 737880.0 -286000.0 -1.4 805490.0 -285000.0 -1.7 623170.0 -247894.84375 -1.41981583882778 -2.6067 -0.996 3161 SpecPlus_000920 CN(Cc1ccc(cc1)C(C)(C)C)Cc2cccc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N23 mock treatment 1145340.0 121000.0 0.59 1232610.0 142000.0 0.84 1061660.0 190595.15625 1.09163231293554 1.4591 0.9719 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 N24 mock treatment 904670.0 -120000.0 -0.58 1095790.0 5050.0 0.03 936660.0 65595.15625 0.375695760288008 -0.1029 -0.148 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O01 mock treatment 965390.0 -58800.0 -0.29 1080660.0 -10100.0 -0.06 853510.0 -17554.84375 -0.100545234533128 -0.2585 -0.8334 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O02 mock treatment 1092060.0 67900.0 0.33 1353920.0 263000.0 1.57 991740.0 120675.15625 0.691166042846615 1.4941 0.8573 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O03 compound treatment 755130.0 -269000.0 -1.31 853490.0 -237000.0 -1.41 647770.0 -223294.84375 -1.27891952526675 -2.3119 -0.9991 1040795 SpecPlus_000921 COc1cccc(O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O04 compound treatment 1168670.0 144000.0 0.71 1243520.0 153000.0 0.91 918510.0 47445.15625 0.271741772843587 1.089 0.9212 2060492 SpecPlus_000922 C[C@H]1C[C@@H](O)[C@]2(O)[C@@]31CC(=O)[C@@](C)(O)[C@]2(C)COC(=O)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O05 compound treatment 647540.0 -377000.0 -1.84 700560.0 -390000.0 -2.32 587930.0 -283134.84375 -1.62165267175017 -3.3383 -0.9887 1054271 SpecPlus_000923 COc1ccc(cc1O)c2cc(=O)c3c(O)c(OC)c(OC)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O06 compound treatment 1033280.0 9090.0 0.04 1009120.0 -81600.0 -0.49 794570.0 -76494.84375 -0.438123637837491 -0.5075 -0.7744 2060493 SpecPlus_000924 COc1ccc2c(=O)c(coc2c1)c3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O07 compound treatment 934900.0 -89300.0 -0.44 964750.0 -126000.0 -0.75 830410.0 -40654.84375 -0.232850309462392 -0.8189 -0.9122 1109169 SpecPlus_000925 COc1ccc2c(=O)c(coc2c1)c3cc4OCOc4cc3OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O08 compound treatment 933520.0 -90700.0 -0.44 1092340.0 1600.0 0.01 802680.0 -68384.84375 -0.391673674301719 -0.4764 -0.8056 3173754 SpecPlus_000926 CO[C@H]1[C@H](C)O[C@H](C[C@@H]1O)O[C@H]2CC[C@@]3(C)[C@H](CCC4C3C[C@@H](O)[C@]5(C)[C@H]([C@H](C[C@]45O)OC(=O)C)C6=CC(=O)OC6)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O09 compound treatment 983310.0 -40900.0 -0.2 975860.0 -115000.0 -0.68 804270.0 -66794.84375 -0.382566961352043 -0.7306 -0.9042 3055391 SpecPlus_000927 OC[C@H]1O[C@@H](Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O10 compound treatment 932570.0 -91600.0 -0.45 1131040.0 40300.0 0.24 732800.0 -138264.84375 -0.791910844693794 -0.5773 -0.6137 1913604 SpecPlus_000928 OC(=O)CCCN1C(=O)c2cccc3cccc(C1=O)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O11 compound treatment 1063390.0 39200.0 0.19 1223490.0 133000.0 0.79 823690.0 -47374.84375 -0.271339058532723 0.4097 0.4784 3100 SpecPlus_000929 COc1c2OCOc2cc3CCN(C)Cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O12 compound treatment 1001280.0 -22900.0 -0.11 1010900.0 -79800.0 -0.47 826720.0 -44344.84375 -0.253984756496547 -0.4854 -0.8826 2060494 SpecPlus_000930 COc1ccc2C(=O)C(Cc3ccc(OC)c(OC)c3)COc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O13 compound treatment 918130.0 -106000.0 -0.52 1073950.0 -16800.0 -0.1 679080.0 -191984.84375 -1.0995917375596 -0.9917 -0.8131 3173755 SpecPlus_000931 C[C@@]12CC(=O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O14 compound treatment 543730.0 -480000.0 -2.35 484160.0 -607000.0 -3.61 427680.0 -443384.84375 -2.53948333224431 -4.904 -0.9814 2060495 SpecPlus_000932 O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3cc(O)c(O)c(O)c3c4c(O)c(O)c(O)cc4[C@H]5Oc6cc(O)cc(O)c6C[C@H]5OC(=O)c7cc(O)c(O)c(O)c7 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O15 compound treatment 705860.0 -318000.0 -1.56 744000.0 -347000.0 -2.06 565160.0 -305904.84375 -1.75206767418045 -3.0999 -0.9933 2060496 SpecPlus_000933 CC1(C)C=C[C@H](O)[C@@]2(C)C1C[C@@H](O)[C@]3(C)C2CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]543)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O16 compound treatment 864990.0 -159000.0 -0.78 992070.0 -98700.0 -0.59 764850.0 -106214.84375 -0.608344712594968 -1.1391 -0.9917 1001994 SpecPlus_000934 C[C@@H](N)[C@@H](O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O17 compound treatment 984900.0 -39300.0 -0.19 1160980.0 70200.0 0.42 848090.0 -22974.84375 -0.131588243455925 0.0544 0.1137 1013678 SpecPlus_000935 Oc1ccccc1C(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O18 compound treatment 934080.0 -90100.0 -0.44 978420.0 -112000.0 -0.67 811960.0 -59104.84375 -0.338522544633167 -0.8352 -0.9616 2060497 SpecPlus_000936 CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O19 compound treatment 896100.0 -128000.0 -0.63 1043590.0 -47200.0 -0.28 758810.0 -112254.84375 -0.642938766818896 -0.8944 -0.9515 2060498 SpecPlus_000937 C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC(=O)O)C3(C)C[C@H](O)C2C4(C)C=CC(=O)C=C14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O20 compound treatment 944480.0 -79700.0 -0.39 1096360.0 5620.0 0.03 739840.0 -131224.84375 -0.751589298048685 -0.6395 -0.7549 2561 SpecPlus_000938 Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O21 compound treatment 964640.0 -59500.0 -0.29 963170.0 -128000.0 -0.76 798460.0 -72604.84375 -0.4158436923191 -0.846 -0.9269 2060499 SpecPlus_000939 OC[C@H]1O[C@@H](Oc2cc(O)c3c(=O)cc(oc3c2)c4ccc(O)cc4)[C@H](O[C@@H]5OC[C@](O)(CO)[C@H]5O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O22 compound treatment 702770.0 -321000.0 -1.57 805920.0 -285000.0 -1.69 685170.0 -185894.84375 -1.06471130871461 -2.4992 -0.9827 2060500 SpecPlus_000940 NCCc1cccc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O23 mock treatment 1083200.0 59000.0 0.29 1165030.0 74300.0 0.44 1036810.0 165745.15625 0.949304126269208 0.9696 0.8928 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 O24 mock treatment 833790.0 -190000.0 -0.93 933510.0 -157000.0 -0.93 876400.0 5335.15625 0.0305570669876873 -1.0592 -0.8029 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P01 mock treatment 975400.0 -48800.0 -0.24 917870.0 -173000.0 -1.03 732480.0 -138584.84375 -0.793743642268572 -1.1894 -0.9007 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P02 mock treatment 1053200.0 29000.0 0.14 935380.0 -155000.0 -0.92 937340.0 66275.15625 0.379590455134411 -0.2324 -0.2304 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P03 compound treatment 420050.0 -604000.0 -2.95 417570.0 -673000.0 -4.0 353440.0 -517624.84375 -2.96469236959273 -5.727 -0.9891 3173759 SpecPlus_000941 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(OC4O[C@@H]5COC(C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P04 compound treatment 954920.0 -69300.0 -0.34 957470.0 -133000.0 -0.79 788050.0 -83014.84375 -0.475466888423586 -0.9274 -0.9423 3055445 SpecPlus_000942 CC(=O)OC(C)(C)[C@@H]1Cc2cc3ccc(=O)oc3cc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P05 compound treatment 1032420.0 8230.0 0.04 1115490.0 24700.0 0.15 889720.0 18655.15625 0.106847266037808 0.1699 0.9121 3173760 SpecPlus_000943 COc1cc2CCN(C)[C@@H]3Cc4cccc(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)c(O)c5)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P06 compound treatment 1039120.0 14900.0 0.07 1084350.0 -6390.0 -0.04 870930.0 -134.84375 -7.72316556168522E-4 0.0197 0.24 2060501 SpecPlus_000944 CC(C)(OC(=O)c1ccccc1)[C@@H]2Cc3cc4ccc(=O)oc4cc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P07 compound treatment 1013690.0 -10500.0 -0.05 1067640.0 -23100.0 -0.14 906840.0 35775.15625 0.204901936288414 0.0094 0.0372 1004713 SpecPlus_000945 CNc1ccccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P08 compound treatment 722640.0 -302000.0 -1.47 821080.0 -270000.0 -1.6 654110.0 -216954.84375 -1.24260722331647 -2.4938 -0.9947 1023016 SpecPlus_000946 COc1ccc2ccc(=O)oc2c1CC=C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P09 compound treatment 1000250.0 -23900.0 -0.12 1106720.0 16000.0 0.1 884370.0 13305.15625 0.0762051815844938 0.0313 0.1856 3173761 SpecPlus_000947 N[C@@H](C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)Cl)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P10 compound treatment 492290.0 -532000.0 -2.6 526730.0 -564000.0 -3.35 444970.0 -426094.84375 -2.4404549882821 -4.8458 -0.99 1463965 SpecPlus_000948 CC1(C)CCc2c3OC(C)(C)C=Cc3c4occ(c5ccc(O)cc5)c(=O)c4c2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P11 compound treatment 1072900.0 48700.0 0.24 1047910.0 -42800.0 -0.25 979040.0 107975.15625 0.618426889097626 0.3474 0.4894 3173762 SpecPlus_000949 CC1OC(O[C@@H]/2CC3O[C@@](O)(C[C@H](O)C3C(=O)O)CC(O)CC(O)C(O)CCC(O)CC(O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C2)C(O)[C@H](N)C1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P12 compound treatment 1003520.0 -20700.0 -0.1 1157090.0 66300.0 0.39 921280.0 50215.15625 0.287606926850256 0.3356 0.673 1296906 SpecPlus_000950 COc1ccc(C(=O)CC(=O)O)c2OC(C)(C)C=Cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P13 compound treatment 56960.0 -967000.0 -4.73 61250.0 -1030000.0 -6.12 44960.0 -826104.84375 -4.73150923167841 -8.9946 -0.9921 1001284 SpecPlus_000951 CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCC6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCC7C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P14 compound treatment 877150.0 -147000.0 -0.72 969120.0 -122000.0 -0.72 768910.0 -102154.84375 -0.585091093364976 -1.1701 -0.9955 1204574 SpecPlus_000952 COc1c(oc2cc3oc(=O)ccc3cc12)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P15 compound treatment 936320.0 -87900.0 -0.43 1039580.0 -51200.0 -0.3 736890.0 -134174.84375 -0.768485400691167 -0.8672 -0.9311 2558 SpecPlus_000953 c1ccc2c(c1)cc3ccc4cccc5ccc2c3c45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P16 compound treatment 791360.0 -233000.0 -1.14 733090.0 -358000.0 -2.13 606790.0 -264274.84375 -1.51363216468672 -2.7586 -0.9688 1101055 SpecPlus_000954 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P17 compound treatment 976240.0 -47900.0 -0.23 1146340.0 55600.0 0.33 749660.0 -121404.84375 -0.695345322472695 -0.3458 -0.4297 2060502 SpecPlus_000955 COc1cc(cc(OC)c1O)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P18 compound treatment 833600.0 -191000.0 -0.93 1029830.0 -60900.0 -0.36 699900.0 -171164.84375 -0.980345345350624 -1.3127 -0.9378 2321 SpecPlus_000956 COc1ccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc2c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P19 compound treatment 855360.0 -169000.0 -0.82 893500.0 -197000.0 -1.17 744540.0 -126524.84375 -0.724670083669138 -1.5718 -0.9783 3173763 SpecPlus_000957 O[C@@H]1C[C@](O)(C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@@H]1O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P20 compound treatment 822400.0 -202000.0 -0.99 872910.0 -218000.0 -1.3 659470.0 -211594.84375 -1.21190786393894 -2.0168 -0.9938 2060503 SpecPlus_000958 C1Oc2ccc(cc2O1)[C@H]3OC[C@@H]4[C@@H](OC[C@H]34)c5ccc6OCOc6c5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P21 compound treatment 742350.0 -282000.0 -1.38 734640.0 -356000.0 -2.12 648800.0 -222264.84375 -1.27302020807293 -2.7526 -0.9731 2060504 SpecPlus_000959 Cc1cc(O)c(C)c(O)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P22 compound treatment 544520.0 -480000.0 -2.34 562300.0 -528000.0 -3.14 508880.0 -362184.84375 -2.07441094764447 -4.365 -0.9842 1001642 SpecPlus_000960 OC[C@H]1OC(C[C@@H]1O)n2cc(c(=O)[nH]c2=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P23 mock treatment 1020330.0 -3860.0 -0.02 1110520.0 19800.0 0.12 936040.0 64975.15625 0.372144714986876 0.2719 0.6958 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1083 P24 mock treatment 900980.0 -123000.0 -0.6 1001960.0 -88800.0 -0.53 938400.0 67335.15625 0.385661597100862 -0.4297 -0.4835 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A01 compound treatment 802410.0 -272000.0 -1.33 778430.0 -247000.0 -1.47 790880.0 -246821.25 -1.41366683876123 -2.4326 -0.9992 1953487 Maybridge1_002289 CC1CN=C(Nc2ccc(Cl)cc2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A02 compound treatment 907060.0 -168000.0 -0.82 937830.0 -87600.0 -0.52 904670.0 -133031.25 -0.761935476155133 -1.2139 -0.9834 1953488 Maybridge1_002290 NNC(=O)[C@H]1C[C@@H]1C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A03 compound treatment 860160.0 -215000.0 -1.05 786010.0 -239000.0 -1.42 781250.0 -256451.25 -1.4688225907772 -2.2755 -0.9899 1953489 Maybridge1_002291 Cc1ccc(NC2=NCC(C)(C)S2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A04 compound treatment 301610.0 -773000.0 -3.78 313700.0 -712000.0 -4.23 307840.0 -729861.25 -4.18027477788813 -7.0381 -0.9988 1037854 Maybridge1_002292 Nc1ccc(O)c2C(=O)c3c(O)ccc(N)c3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A05 compound treatment 1072860.0 -1900.0 -0.01 894530.0 -131000.0 -0.78 956200.0 -81501.25 -0.466797791691715 -0.7244 -0.7979 1953490 Maybridge1_002293 CCOC(=O)C(O)(c1ccc(N)c(OC)c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A06 compound treatment 1056260.0 -18500.0 -0.09 1034030.0 8560.0 0.05 926240.0 -111461.25 -0.638393464630275 -0.3914 -0.6051 1953491 Maybridge1_002294 CN1C2CCC1CC(=NOC(=O)c3ccc(Cl)cc3)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A07 compound treatment 1134130.0 59400.0 0.29 1020990.0 -4480.0 -0.03 1026970.0 -10731.25 -0.0614631530447904 0.1166 0.3916 1291574 Maybridge1_002295 Cn1c(Nc2ccccc2)cc(=O)n(C)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A08 compound treatment 1152410.0 77600.0 0.38 1050480.0 25000.0 0.15 1071260.0 33558.75 0.192207486289282 0.4159 0.923 1872890 Maybridge1_002296 Cc1ccc(OC(=O)c2ccc(cc2)[N+](=O)[O-])c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A09 compound treatment 1014120.0 -60600.0 -0.3 1138890.0 113000.0 0.67 980190.0 -57511.25 -0.329395248507602 0.0282 0.0349 1953492 Maybridge1_002297 Nc1nc(ns1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A10 compound treatment 906350.0 -168000.0 -0.82 897530.0 -128000.0 -0.76 837000.0 -200701.25 -1.1495148882964 -1.578 -0.9829 1534164 Maybridge1_002298 COc1ccccc1N2CCN(Cc3ccccc3Cl)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A11 compound treatment 993030.0 -81700.0 -0.4 1041480.0 16000.0 0.1 987580.0 -50121.25 -0.28706907951508 -0.3413 -0.6814 1529433 Maybridge1_002299 COc1ccccc1C2CCN(CC2)C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A12 compound treatment 1009040.0 -65700.0 -0.32 1007940.0 -17500.0 -0.1 939750.0 -97951.25 -0.56101504202013 -0.5695 -0.8698 1953493 Maybridge1_002300 O=C(CN1CCC(CC1)NC(=O)c2ccccc2)N(C3CCCCC3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A13 compound treatment 1084830.0 10100.0 0.05 969530.0 -55900.0 -0.33 866530.0 -171171.25 -0.980382037098947 -0.7297 -0.704 1025920 Maybridge1_002301 Oc1ccc([N+](=O)[O-])c2C(=O)c3ccccc3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A14 compound treatment 1149340.0 74600.0 0.36 1104190.0 78700.0 0.47 1083730.0 46028.75 0.2636293167814 0.6328 0.9749 1371569 Maybridge1_002302 O=C(OCc1ccccc1)N2C3CC3NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A15 compound treatment 1029180.0 -45600.0 -0.22 1094080.0 68600.0 0.41 1066530.0 28828.75 0.1651164471371 0.2023 0.4101 1083848 Maybridge1_002303 CCCCC(NC(=O)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A16 compound treatment 1176730.0 102000.0 0.5 1019130.0 -6340.0 -0.04 1127200.0 89498.75 0.512603412330104 0.5618 0.7849 1020730 Maybridge1_002304 Clc1cc(Cl)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A17 compound treatment 864000.0 -211000.0 -1.03 814360.0 -211000.0 -1.26 817680.0 -220021.25 -1.2601700418736 -2.0469 -0.9959 1953494 Maybridge1_002305 [O-][N+](=O)c1ccc(o1)c2nnc(S)s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A18 compound treatment 1225640.0 151000.0 0.74 1030900.0 5430.0 0.03 985990.0 -51711.25 -0.296175792464756 0.2732 0.3437 1953495 Maybridge1_002306 CCOC(=O)[C@@H]1[C@H]([C@H](C(=O)OCC)[C@](C)(O)CC1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A19 compound treatment 1205450.0 131000.0 0.64 1143630.0 118000.0 0.7 1097980.0 60278.75 0.345246083783218 0.9736 0.9638 1953496 Maybridge1_002307 COc1ccc(CC2CCC(=NOC(=O)c3cccc(c3)C(F)(F)F)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A20 compound treatment 1127160.0 52400.0 0.26 1143550.0 118000.0 0.7 1131770.0 94068.75 0.538778052694898 0.8643 0.9381 1576383 Maybridge1_002308 CC(C)CCOC(=O)C1(CC2(C1)COC(OC2)c3ccccc3)C(=O)OCCC(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A21 compound treatment 837070.0 -238000.0 -1.16 820890.0 -205000.0 -1.22 833000.0 -204701.25 -1.17242485798112 -2.0498 -0.9998 1953497 Maybridge1_002309 CCOC(=O)/C(=N/Nc1ccccc1C)/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A22 compound treatment 1130560.0 55800.0 0.27 915430.0 -110000.0 -0.65 1008240.0 -29461.25 -0.168739086093496 -0.3178 -0.4362 1953498 Maybridge1_002310 CCOC(=O)C(CCC(=O)O)(CCC(=O)O)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A23 mock treatment 1090460.0 15700.0 0.08 1031170.0 5700.0 0.03 1020640.0 -17061.25 -0.0977181800708612 0.0074 0.0577 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 A24 mock treatment 922120.0 -153000.0 -0.75 973440.0 -52000.0 -0.31 953490.0 -84211.25 -0.482319296153114 -0.8877 -0.9438 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B01 compound treatment 1139560.0 64800.0 0.32 1015070.0 -10400.0 -0.06 900700.0 -137001.25 -0.784673621067218 -0.306 -0.3606 1953499 Maybridge1_002311 O[C@H]1CC2CCC1N(Cc3ccccc3)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B02 compound treatment 582240.0 -493000.0 -2.41 589080.0 -436000.0 -2.6 582140.0 -455561.25 -2.60922360675839 -4.394 -0.9993 1936533 Maybridge1_002312 CCOc1ccc(Br)cc1C=C2C(=O)NC(=S)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B03 compound treatment 1050080.0 -24700.0 -0.12 1002180.0 -23300.0 -0.14 924520.0 -113181.25 -0.648244751594705 -0.5239 -0.7775 1953500 Maybridge1_002313 COc1ccc(cc1)/C(=N/O)/C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B04 compound treatment 488010.0 -587000.0 -2.87 494750.0 -531000.0 -3.16 507950.0 -529751.25 -3.03414626948575 -5.229 -0.9992 1577344 Maybridge1_002314 COc1cccc(NC(=S)NC2CC(C)CC(C)(C)C2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B05 compound treatment 1004000.0 -70800.0 -0.35 966240.0 -59200.0 -0.35 904670.0 -133031.25 -0.761935476155133 -0.8429 -0.9285 1953501 Maybridge1_002315 ON=C1C/C=C\CC(=NO)C/C=C\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B06 compound treatment 1150990.0 76200.0 0.37 1094440.0 69000.0 0.41 1134620.0 96918.75 0.555101406095262 0.7723 0.9848 1050941 Maybridge1_002316 Clc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B07 compound treatment 1096960.0 22200.0 0.11 1128880.0 103000.0 0.61 1046210.0 8508.75 0.0487338011387173 0.4458 0.7118 1953502 Maybridge1_002317 Cc1ccc(cc1)S(=O)(=O)OCC2(CCC3CC2)C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B08 compound treatment 996640.0 -78100.0 -0.38 1012010.0 -13500.0 -0.08 1060330.0 22628.75 0.129605994125782 -0.1918 -0.4666 1953503 Maybridge1_002318 Oc1c(Br)cc(Br)cc1/C=N/c2ccc(Cc3ccc(\N=C\c4cc(Br)cc(Br)c4O)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B09 compound treatment 1141050.0 66300.0 0.32 1042130.0 16700.0 0.1 1023490.0 -14211.25 -0.0813948266704976 0.1972 0.5661 1068565 Maybridge1_002319 OC(=O)C1CCCC1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B10 compound treatment 827680.0 -247000.0 -1.21 733490.0 -292000.0 -1.74 707930.0 -329771.25 -1.88876233509813 -2.7899 -0.984 1513655 Maybridge1_002320 CN(C)c1ccc(CC2C(=O)Nc3ccccc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B11 compound treatment 32400.0 -1040000.0 -5.09 41280.0 -984000.0 -5.85 42400.0 -995301.25 -5.70058036616621 -9.6105 -0.9983 1953504 Maybridge1_002321 Brc1ccc2NC(=O)/C(=C\C(=O)c3ccc(cc3)c4ccccc4)/c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B12 compound treatment 225280.0 -849000.0 -4.15 306040.0 -719000.0 -4.28 266150.0 -771551.25 -4.41905393692713 -7.4176 -0.9997 1953505 Maybridge1_002322 CSC1=C(C#N)C(=O)NC(S1)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B13 compound treatment 1047290.0 -27500.0 -0.13 1121330.0 95900.0 0.57 1123070.0 85368.75 0.48894886863063 0.5339 0.6998 1953506 Maybridge1_002323 OC(=O)c1ccc(s1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B14 compound treatment 1251800.0 177000.0 0.86 1018840.0 -6630.0 -0.04 1086400.0 48698.75 0.278921721545951 0.6377 0.701 1953507 Maybridge1_002324 Brc1ccc(CSc2nnc(SCc3ccc(Br)cc3)s2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B15 compound treatment 1283290.0 209000.0 1.02 1131590.0 106000.0 0.63 1035600.0 -2101.25 -0.012034893450005 0.9456 0.789 1953508 Maybridge1_002325 OC(=O)c1csc(n1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B16 compound treatment 483850.0 -591000.0 -2.89 717760.0 -308000.0 -1.83 580960.0 -456741.25 -2.61598204781539 -4.2337 -0.9836 1071578 Maybridge1_002326 Clc1ccccc1C2Nc3ccccc3S2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B17 compound treatment 1072000.0 -2760.0 -0.01 1073180.0 47700.0 0.28 1043870.0 6168.75 0.0353314688731556 0.1764 0.6164 1953509 Maybridge1_002327 CCC(C)(C)C1CCC(=O)/C(=C\c2ccccc2)/C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B18 compound treatment 1158420.0 83700.0 0.41 1193370.0 168000.0 1.0 978930.0 -58771.25 -0.336611888958289 0.6181 0.5469 1232551 Maybridge1_002328 COc1cc(cc(OC)c1OC)C(=O)c2c(C)c(C)c(C)c(C)c2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B19 compound treatment 1002970.0 -71800.0 -0.35 988510.0 -37000.0 -0.22 1039780.0 2078.75 0.0119060248705284 -0.3225 -0.7789 1953510 Maybridge1_002329 FC(F)(F)c1cccc(NC(=O)CC#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B20 compound treatment 317970.0 -757000.0 -3.7 339520.0 -686000.0 -4.08 280540.0 -757161.25 -4.33663532098635 -6.9936 -0.9979 1953511 Maybridge1_002330 CN(C)c1ccc(cc1)C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B21 compound treatment 1198240.0 123000.0 0.6 1111780.0 86300.0 0.51 1151800.0 114098.75 0.653499725891138 1.0219 0.9952 1953512 Maybridge1_002331 COc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B22 compound treatment 1094720.0 20000.0 0.1 964320.0 -61200.0 -0.36 955360.0 -82341.25 -0.471608885325507 -0.4259 -0.7058 1953513 Maybridge1_002332 Cc1onc(c1C(=O)NN)c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B23 mock treatment 1119440.0 44700.0 0.22 986570.0 -38900.0 -0.23 1089210.0 51508.75 0.295015975249467 0.1628 0.3753 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 B24 mock treatment 987240.0 -87500.0 -0.43 1084590.0 59100.0 0.35 1107710.0 70008.75 0.400974585041302 0.1876 0.2744 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C01 compound treatment 934950.0 -140000.0 -0.68 1016960.0 -8510.0 -0.05 975000.0 -62701.25 -0.359120934173527 -0.6309 -0.8158 1953514 Maybridge1_002333 CC1CN=C(Nc2ccc(F)cc2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C02 compound treatment 1195040.0 120000.0 0.59 1047680.0 22200.0 0.13 1046340.0 8638.75 0.0494783751534707 0.4441 0.7348 1013499 Maybridge1_002334 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C03 compound treatment 902720.0 -172000.0 -0.84 893340.0 -132000.0 -0.79 825230.0 -212471.25 -1.21692747409369 -1.6415 -0.9802 1953515 Maybridge1_002335 CC1(C)CN=C(Nc2ccc(Cl)cc2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C04 compound treatment 851520.0 -223000.0 -1.09 829160.0 -196000.0 -1.17 807170.0 -230531.25 -1.32036598722021 -2.066 -0.9968 1953516 Maybridge1_002336 CC1(C)N(O)C(=O)C(C)(C)N(O)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C05 compound treatment 1056080.0 -18700.0 -0.09 974450.0 -51000.0 -0.3 918180.0 -119521.25 -0.684557053544988 -0.6231 -0.826 1953517 Maybridge1_002337 FC(F)(F)c1nc2ccccc2[nH]c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C06 compound treatment 1095680.0 20900.0 0.1 1097760.0 72300.0 0.43 1023970.0 -13731.25 -0.0786456303083311 0.2618 0.5833 1953518 Maybridge1_002338 CN1C2CCC1CC(=NOC(=O)c3ccc(cc3)[N+](=O)[O-])C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C07 compound treatment 1190290.0 116000.0 0.56 1017840.0 -7630.0 -0.05 1024360.0 -13341.25 -0.0764119082640708 0.2556 0.4473 1774966 Maybridge1_002339 [O-][N+](=O)c1ccc(/C=C/c2ccc(cc2)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C08 compound treatment 822520.0 -252000.0 -1.23 820520.0 -205000.0 -1.22 808720.0 -228981.25 -1.31148837396738 -2.1724 -0.9995 1953519 Maybridge1_002340 Cc1ccc(OC(=O)c2ccc(Cl)cc2)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C09 compound treatment 1204390.0 130000.0 0.63 1150020.0 125000.0 0.74 1098890.0 61188.75 0.350458101886492 0.9956 0.9614 1953520 Maybridge1_002341 CCNc1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C10 compound treatment 807290.0 -267000.0 -1.31 863760.0 -162000.0 -0.96 784430.0 -253271.25 -1.45060916487784 -2.1472 -0.9866 1579020 Maybridge1_002342 COc1ccccc1N2CCN(Cc3ccc(Cl)c(Cl)c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C11 compound treatment 1086790.0 12000.0 0.06 988050.0 -37400.0 -0.22 955720.0 -81981.25 -0.469546988053882 -0.3656 -0.6992 1039501 Maybridge1_002343 COc1ccc2[nH]c(C)cc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C12 compound treatment 311440.0 -763000.0 -3.73 269820.0 -756000.0 -4.49 313920.0 -723781.25 -4.14545162396735 -7.1409 -0.9971 1953521 Maybridge1_002344 CC1(C)C(NCC(=O)N(C2CCCCC2)c3ccccc3)C4(C)CCC1C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C13 compound treatment 1170310.0 95500.0 0.47 1206210.0 181000.0 1.07 1065310.0 27608.75 0.15812890638326 0.9813 0.83 1953522 Maybridge1_002345 Cc1cc(N)n(n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C14 compound treatment 274500.0 -800000.0 -3.91 267200.0 -758000.0 -4.51 236450.0 -801251.25 -4.58916046183619 -7.5103 -0.9976 1953523 Maybridge1_002346 Nc1nc(cc(n1)C(F)(F)F)c2ccc(cc2)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C15 compound treatment 1266600.0 192000.0 0.94 1129470.0 104000.0 0.62 1064290.0 26588.75 0.152286864113656 0.9861 0.8702 1026 Maybridge1_002347 CC(=O)NC(Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C16 compound treatment 1222810.0 148000.0 0.72 1272490.0 247000.0 1.47 1235230.0 197528.75 1.1313444185902 1.9189 0.9642 1953524 Maybridge1_002348 CC(=O)c1cc(F)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C17 compound treatment 1267750.0 193000.0 0.94 1212980.0 188000.0 1.12 1142370.0 104668.75 0.599489472359408 1.5343 0.972 1953525 Maybridge1_002349 CCCC(CCC)C(C(=O)O)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C18 compound treatment 1040800.0 -34000.0 -0.17 922450.0 -103000.0 -0.61 938290.0 -99411.25 -0.569377180955053 -0.7782 -0.9127 1010667 Maybridge1_002350 Nc1c(ccc2C(=O)c3ccccc3C(=O)c12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C19 compound treatment 1210090.0 135000.0 0.66 1173190.0 148000.0 0.88 1138420.0 100718.75 0.576865877295747 1.2219 0.9842 1953526 Maybridge1_002351 COc1ccc(CC2CCC(=NOC(=O)c3ccc(cc3)C(C)(C)C)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C20 compound treatment 1221440.0 147000.0 0.72 1066880.0 41400.0 0.25 1069810.0 32108.75 0.183902622278571 0.6621 0.8491 1059445 Maybridge1_002352 CC(SCc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C21 compound treatment 1312250.0 237000.0 1.16 1213330.0 188000.0 1.12 1118880.0 81178.75 0.464950675385885 1.5833 0.9444 1953527 Maybridge1_002353 CCOC(=O)/C(=N/Nc1ccccc1)/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C22 compound treatment 676530.0 -398000.0 -1.95 637850.0 -388000.0 -2.31 475870.0 -561831.25 -3.21788422635722 -4.312 -0.9776 1953528 Maybridge1_002354 CC(C)(C)C#CC(O)(C#CC(C)(C)C)C#CC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C23 mock treatment 1160430.0 85700.0 0.42 949500.0 -76000.0 -0.45 1041060.0 3358.75 0.0192372151696391 -0.0081 -0.0131 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 C24 mock treatment 1011240.0 -63500.0 -0.31 1084160.0 58700.0 0.35 1049930.0 12228.75 0.0700400729455078 0.0627 0.1329 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D01 compound treatment 810240.0 -265000.0 -1.29 873320.0 -152000.0 -0.9 769440.0 -268261.25 -1.53646427627134 -2.1556 -0.9789 1953529 Maybridge1_002355 C1C2CC3CC1CC(C2)C3c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D02 compound treatment 710890.0 -364000.0 -1.78 639040.0 -386000.0 -2.3 661720.0 -375981.25 -2.15342975988087 -3.5964 -0.9945 1953530 Maybridge1_002356 COc1cc(OC)c(C=C2C(=O)NC(=S)NC2=O)c(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D03 compound treatment 1025560.0 -49200.0 -0.24 968740.0 -56700.0 -0.34 977790.0 -59911.25 -0.343141230318434 -0.5317 -0.9884 1026485 Maybridge1_002357 Cc1ccc(cc1)S(=O)(=O)NCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D04 compound treatment 806730.0 -268000.0 -1.31 860800.0 -165000.0 -0.98 925240.0 -112461.25 -0.644120957051455 -1.6933 -0.9635 1953531 Maybridge1_002358 CCCCNC(=S)Nc1cccc(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D05 compound treatment 1021280.0 -53500.0 -0.26 975810.0 -49700.0 -0.3 966180.0 -71521.25 -0.409637417328337 -0.5579 -0.9811 1039144 Maybridge1_002359 OC(=O)C1C(C2CC1C=C2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D06 compound treatment 1141950.0 67200.0 0.33 1051810.0 26300.0 0.16 994400.0 -43301.25 -0.248007581202631 0.1368 0.3107 1953532 Maybridge1_002360 CC(C)(C)NC(=O)NCCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D07 compound treatment 619850.0 -455000.0 -2.22 701880.0 -324000.0 -1.92 624110.0 -413591.25 -2.36884074984146 -3.7619 -0.9964 1953533 Maybridge1_002361 BrC1(CC2CC3(Br)C1)CC(Br)(C2)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D08 compound treatment 877040.0 -198000.0 -0.97 834930.0 -191000.0 -1.13 747730.0 -289971.25 -1.66080813673516 -2.1708 -0.9732 1913713 Maybridge1_002362 COc1ccc(/C=N/c2ccc(O)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D09 compound treatment 823360.0 -251000.0 -1.23 800610.0 -225000.0 -1.34 778080.0 -259621.25 -1.48697874175234 -2.3397 -0.9969 1953534 Maybridge1_002363 COc1cc(/C=C/2\NC(=O)NC2=O)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D10 compound treatment 1066400.0 -8360.0 -0.04 1074720.0 49200.0 0.29 1037320.0 -381.25 -0.00218360648557496 0.1442 0.4878 1164268 Maybridge1_002364 O=C1Nc2ccccc2C1Cc3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D11 compound treatment 817890.0 -257000.0 -1.26 775400.0 -250000.0 -1.49 813120.0 -224581.25 -1.28628740731418 -2.3258 -0.9971 1953535 Maybridge1_002365 CC(=O)N1C(=O)/C(=N/Nc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])/c3cc(Br)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D12 compound treatment 1227900.0 153000.0 0.75 1172720.0 147000.0 0.88 1257760.0 220058.75 1.2603848228394 1.6652 0.9753 1209197 Maybridge1_002366 Nc1ccccc1C(=O)NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D13 compound treatment 1331470.0 257000.0 1.25 1356170.0 331000.0 1.97 1279810.0 242108.75 1.38667603072642 2.6601 0.9803 1012508 Maybridge1_002367 OC(=O)c1ccnc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D14 compound treatment 967200.0 -108000.0 -0.53 985160.0 -40300.0 -0.24 989470.0 -48231.25 -0.276244118839049 -0.6013 -0.9391 1953536 Maybridge1_002368 Clc1ccccc1/C=N/NC(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D15 compound treatment 1282980.0 208000.0 1.02 1144280.0 119000.0 0.71 1177090.0 139388.75 0.798348009222786 1.4562 0.9882 1945130 Maybridge1_002369 Cc1oc(cc1C(=O)O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D16 compound treatment 863200.0 -212000.0 -1.03 931270.0 -94200.0 -0.56 968440.0 -69261.25 -0.396693284456469 -1.1492 -0.9262 1953537 Maybridge1_002370 [O-][N+](=O)c1ccc(cc1)C2Nc3ccccc3S2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D17 compound treatment 1240100.0 165000.0 0.81 947000.0 -78500.0 -0.47 952910.0 -84791.25 -0.485641241757398 -0.0834 -0.0793 1087610 Maybridge1_002371 COc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D18 compound treatment 754900.0 -320000.0 -1.56 742330.0 -283000.0 -1.68 897870.0 -139831.25 -0.800882424619158 -2.3368 -0.9605 1953538 Maybridge1_002372 Cc1c(C)c(C)c(CSCC(=O)N/N=C/C=C/c2ccccc2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D19 compound treatment 1016210.0 -58600.0 -0.29 1108000.0 82500.0 0.49 1277640.0 239938.75 1.37424737217246 0.9116 0.613 1052222 Maybridge1_002373 O=C1NC(=O)C(=Cc2ccncc2)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D20 compound treatment 645090.0 -430000.0 -2.1 630260.0 -395000.0 -2.35 612500.0 -425201.25 -2.43533693685136 -3.9749 -0.9981 1953539 Maybridge1_002374 COc1cc(/C=N/NC(=O)c2ccc(cc2)N(C)C)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D21 compound treatment 95560.0 -979000.0 -4.78 76220.0 -949000.0 -5.64 102050.0 -935651.25 -5.35893544324281 -9.1152 -0.9977 1953540 Maybridge1_002375 O=C1NC(=S)NC(=O)C1=C/C=C/c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D22 compound treatment 1250170.0 175000.0 0.86 1064980.0 39500.0 0.23 1145120.0 107418.75 0.615240076517654 0.9856 0.9119 1104953 Maybridge1_002376 COc1cc2COC(=O)Cc2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D23 mock treatment 1031470.0 -43300.0 -0.21 1055530.0 30100.0 0.18 965610.0 -72091.25 -0.412902088008409 -0.2573 -0.5176 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 D24 mock treatment 1137860.0 63100.0 0.31 1010830.0 -14600.0 -0.09 1081530.0 43828.75 0.251028833454803 0.2727 0.6699 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E01 compound treatment 905620.0 -169000.0 -0.83 934330.0 -91100.0 -0.54 969720.0 -67981.25 -0.389362094157359 -1.0148 -0.9554 1953541 Maybridge1_002377 CC1CN=C(Nc2ccc(F)c(Cl)c2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E02 compound treatment 1082580.0 7820.0 0.04 1000430.0 -25000.0 -0.15 968720.0 -68981.25 -0.395089586578539 -0.292 -0.6888 1045555 Maybridge1_002378 N#CCc1cccc(CC#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E03 compound treatment 930680.0 -144000.0 -0.7 922520.0 -103000.0 -0.61 942820.0 -94881.25 -0.543431640287107 -1.0736 -0.9944 1953542 Maybridge1_002379 CC1(C)CN=C(Nc2ccc(F)cc2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E04 compound treatment 1169280.0 94500.0 0.46 1051240.0 25800.0 0.15 981960.0 -55741.25 -0.319257586922113 0.1708 0.2934 1080378 Maybridge1_002380 CC1(CCC2(O)CC1)C(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E05 compound treatment 1248750.0 174000.0 0.85 995690.0 -29800.0 -0.18 1160640.0 122938.75 0.704130758894371 0.7951 0.7112 1953543 Maybridge1_002381 O/N=C\1/CCCc2nonc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E06 compound treatment 688530.0 -386000.0 -1.89 604800.0 -421000.0 -2.5 512320.0 -525381.25 -3.0091171276052 -4.2711 -0.9831 1706026 Maybridge1_002382 CC1(C)C(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)C3(C)CCC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E07 compound treatment 1379150.0 304000.0 1.49 1087270.0 61800.0 0.37 1201120.0 163418.75 0.935979652103747 1.6112 0.8975 1002835 Maybridge1_002383 CCOc1ccc(NC(=O)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E08 compound treatment 852730.0 -222000.0 -1.08 876400.0 -149000.0 -0.89 829810.0 -207891.25 -1.19069555880469 -1.8256 -0.9929 1953544 Maybridge1_002384 Cc1ccc(OC(=O)c2cccs2)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E09 compound treatment 1209040.0 134000.0 0.66 1255390.0 230000.0 1.37 1298560.0 260858.75 1.49406651362355 2.0307 0.9539 1018520 Maybridge1_002385 NS(=O)(=O)c1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E10 compound treatment 1198240.0 123000.0 0.6 1118150.0 92700.0 0.55 1170900.0 133198.75 0.76289483113568 1.107 0.9902 1953545 Maybridge1_002386 COc1ccccc1N2CCN(Cc3cccc(c3)[N+](=O)[O-])CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E11 compound treatment 1234000.0 159000.0 0.78 1186400.0 161000.0 0.96 1251950.0 214248.75 1.22710809187234 1.7102 0.983 1953546 Maybridge1_002387 Cc1[nH]c2ccccc2c1CCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E12 compound treatment 1071690.0 -3070.0 -0.02 966650.0 -58800.0 -0.35 1000700.0 -37001.25 -0.211924378949195 -0.333 -0.8136 1953547 Maybridge1_002388 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E13 compound treatment 1409660.0 335000.0 1.64 1243040.0 218000.0 1.29 1254260.0 216558.75 1.24033859936526 2.4078 0.9921 1953548 Maybridge1_002389 CC(=O)NC(CCCNC(=N)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E14 compound treatment 640320.0 -434000.0 -2.12 591700.0 -434000.0 -2.58 561140.0 -476561.25 -2.72950094760318 -4.2906 -0.9946 1135193 Maybridge1_002390 CCc1cc2c(C)cc(=O)oc2cc1OCC(=O)Nc3cccc(C)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E15 compound treatment 1402720.0 328000.0 1.6 1107210.0 81700.0 0.49 1263970.0 226268.75 1.29595255077492 1.954 0.9228 1953549 Maybridge1_002391 CC(=O)N[C@@H](Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E16 compound treatment 1321200.0 246000.0 1.2 1128320.0 103000.0 0.61 1127110.0 89408.75 0.512087938012198 1.3439 0.9305 1953550 Maybridge1_002392 OC(=O)c1cc(F)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E17 compound treatment 994760.0 -80000.0 -0.39 884280.0 -141000.0 -0.84 980700.0 -57001.25 -0.3264742273728 -0.8989 -0.9154 1953551 Maybridge1_002393 COc1cc(Br)c(OC)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E18 compound treatment 1272290.0 198000.0 0.97 1170630.0 145000.0 0.86 1273760.0 236058.75 1.35202470157828 1.8361 0.9808 1323862 Maybridge1_002394 c1ccc(cc1)c2nc(no2)c3noc(n3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E19 compound treatment 1286420.0 212000.0 1.03 1187360.0 162000.0 0.96 1290090.0 252388.75 1.44555465281615 1.9874 0.9832 1953552 Maybridge1_002395 COc1ccc(CC2CCC(=NOC(=O)c3ccc(cc3)[N+](=O)[O-])CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E20 compound treatment 1130770.0 56000.0 0.27 1173150.0 148000.0 0.88 1212760.0 175058.75 1.00264766388628 1.2439 0.9142 1953553 Maybridge1_002396 CCOC(=O)C(CCC(=O)O)(CCC(=O)O)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E21 compound treatment 1313760.0 239000.0 1.17 1183110.0 158000.0 0.94 1298880.0 261178.75 1.49589931119833 2.079 0.9823 1638020 Maybridge1_002397 CN1C(=O)c2ccc(Oc3ccc(cc3)C(C)(C)c4ccc(Oc5ccc6C(=O)N(C)C(=O)c6c5)cc4)cc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E22 compound treatment 1313520.0 239000.0 1.17 1138170.0 113000.0 0.67 1199290.0 161588.75 0.925498340972987 1.5948 0.9766 1414356 Maybridge1_002398 OC1CCC2CC1CC2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E23 mock treatment 1062990.0 -11800.0 -0.06 1075430.0 50000.0 0.3 1070110.0 32408.75 0.185620870004925 0.2455 0.6915 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 E24 mock treatment 1069070.0 -5690.0 -0.03 1124000.0 98500.0 0.59 1124320.0 86618.75 0.496108234157105 0.6086 0.7923 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F01 compound treatment 998240.0 -76500.0 -0.37 960480.0 -65000.0 -0.39 942830.0 -94871.25 -0.543374365362895 -0.7527 -0.9846 1666767 Maybridge1_002399 OC(=O)C1C2CC3CC(C2)C(=O)C1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F02 compound treatment 1034420.0 -40300.0 -0.2 1072760.0 47300.0 0.28 1142680.0 104978.75 0.601264995009974 0.3957 0.5715 1953554 Maybridge1_002400 CC(C=C1C(=O)NC(=S)NC1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F03 compound treatment 980590.0 -94200.0 -0.46 896060.0 -129000.0 -0.77 901470.0 -136231.25 -0.78026345190291 -1.1604 -0.9763 1953555 Maybridge1_002401 Cc1ccc(cc1)S(=O)(=O)OCC2(CC3CC4CC(C3)C2)C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F04 compound treatment 843240.0 -232000.0 -1.13 797770.0 -228000.0 -1.35 814200.0 -223501.25 -1.28010171549931 -2.1739 -0.9973 1953556 Maybridge1_002402 COc1cccc(NC(=S)Nc2ccc(Br)cc2Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F05 compound treatment 934460.0 -140000.0 -0.69 950090.0 -75400.0 -0.45 968820.0 -68881.25 -0.394516837336421 -0.8823 -0.9706 1041551 Maybridge1_002403 OC(=O)C1C(C2c3ccccc3C1c4ccccc24)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F06 compound treatment 1264160.0 189000.0 0.93 1076080.0 50600.0 0.3 1245550.0 207848.75 1.19045214037678 1.3953 0.9075 1052223 Maybridge1_002404 O=C1NC(=O)C(=Cc2ccccn2)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F07 compound treatment 1028520.0 -46200.0 -0.23 1096580.0 71100.0 0.42 886750.0 -150951.25 -0.864572140342683 -0.3855 -0.3899 1953557 Maybridge1_002405 COC(=O)c1ccc2c(C)cc(=O)oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F08 compound treatment 589300.0 -485000.0 -2.37 584400.0 -441000.0 -2.62 566100.0 -471601.25 -2.70109258519412 -4.4432 -0.9985 1953558 Maybridge1_002406 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(cc2)S(=O)(=O)c3ccc(\N=C\c4cc(Cl)cc(Cl)c4O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F09 compound treatment 930270.0 -144000.0 -0.71 995400.0 -30100.0 -0.18 892960.0 -144741.25 -0.829004412407153 -0.9895 -0.8967 1953559 Maybridge1_002407 Oc1ccc(/C=C/2\NC(=O)NC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F10 compound treatment 1021360.0 -53400.0 -0.26 1006150.0 -19300.0 -0.11 1052690.0 14988.75 0.0858479520279652 -0.1674 -0.5623 1585399 Maybridge1_002408 Cc1cc(C)c(C(=O)O)c(CC(C)(C)C(=O)O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F11 compound treatment 1175110.0 100000.0 0.49 1041670.0 16200.0 0.1 1037970.0 268.75 0.00153926358819219 0.3396 0.6796 1583841 Maybridge1_002409 COc1ccc2nccc(C(OC(=O)C)C3CC4CCN3CC4C=C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F12 compound treatment 1289670.0 215000.0 1.05 1161650.0 136000.0 0.81 1176700.0 138998.75 0.796114287178526 1.5334 0.9914 1953560 Maybridge1_002410 Nc1ccccc1C(=O)NCCCN2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F13 compound treatment 1026240.0 -48500.0 -0.24 957600.0 -67900.0 -0.4 1067240.0 29538.75 0.169182966756138 -0.2722 -0.5469 1034432 Maybridge1_002411 OC(=O)c1cc2ccccc2cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F14 compound treatment 807060.0 -268000.0 -1.31 740720.0 -285000.0 -1.69 732590.0 -305111.25 -1.74752237199183 -2.7417 -0.9924 1680127 Maybridge1_002412 COc1ccc(cc1)C2Nc3ccccc3-n4cccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F15 compound treatment 1341190.0 266000.0 1.3 1054750.0 29300.0 0.17 1326430.0 288728.75 1.65369172740184 1.8068 0.8556 1953561 Maybridge1_002413 Cc1c(cnn1c2ccccc2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F16 compound treatment 966080.0 -109000.0 -0.53 873620.0 -152000.0 -0.9 912060.0 -125641.25 -0.719609307162611 -1.2434 -0.9783 1953562 Maybridge1_002414 O=C(CC#N)NNC(=S)NC1CC2CC1C=C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F17 compound treatment 1254990.0 180000.0 0.88 989660.0 -35800.0 -0.21 1033000.0 -4701.25 -0.0269263737450736 0.3699 0.4081 1049246 Maybridge1_002415 O=C1NC(=O)C(=Cc2ccc3OCOc3c2)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F18 compound treatment 997340.0 -77400.0 -0.38 1175400.0 150000.0 0.89 843120.0 -194581.25 -1.11446263467878 -0.3471 -0.2351 1953563 Maybridge1_002416 CC(O)c1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F19 compound treatment 671480.0 -403000.0 -1.97 560910.0 -465000.0 -2.76 560160.0 -477541.25 -2.73511389017593 -4.3117 -0.9893 1926891 Maybridge1_002417 Oc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F20 compound treatment 747280.0 -327000.0 -1.6 815410.0 -210000.0 -1.25 830450.0 -207251.25 -1.18702996365513 -2.3303 -0.991 1953564 Maybridge1_002418 COc1cc(/C=N/NC(=O)c2ccc(cc2)N(C)C)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F21 compound treatment 1166280.0 91500.0 0.45 1011150.0 -14300.0 -0.09 1089840.0 52138.75 0.298624295474811 0.3814 0.7006 1953565 Maybridge1_002419 Clc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F22 compound treatment 699680.0 -375000.0 -1.83 616040.0 -409000.0 -2.43 739360.0 -298341.25 -1.70874724830044 -3.4503 -0.9876 1953566 Maybridge1_002420 Clc1cccc(Cl)c1CSC(=N)Nc2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F23 mock treatment 1170560.0 95800.0 0.47 976880.0 -48600.0 -0.29 1015070.0 -22631.25 -0.129620312856835 0.0286 0.0505 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 F24 mock treatment 1092740.0 18000.0 0.09 1069440.0 44000.0 0.26 987540.0 -50161.25 -0.287298179211927 0.0358 0.0899 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G01 compound treatment 821350.0 -253000.0 -1.24 838880.0 -187000.0 -1.11 915300.0 -122401.25 -0.701052231717987 -1.7602 -0.9755 1953567 Maybridge1_002421 CC1CN=C(Nc2cccc(c2)C(F)(F)F)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G02 compound treatment 977120.0 -97600.0 -0.48 886730.0 -139000.0 -0.83 877210.0 -160491.25 -0.919212418040742 -1.2825 -0.9686 1004812 Maybridge1_002422 OCCc1c[nH]c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G03 compound treatment 747760.0 -327000.0 -1.6 799840.0 -226000.0 -1.34 824480.0 -213221.25 -1.22122309340958 -2.4021 -0.9937 1953568 Maybridge1_002423 CC1(C)CN=C(Nc2cccc(c2)C(F)(F)F)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G04 compound treatment 1081810.0 7050.0 0.03 986160.0 -39300.0 -0.23 1036060.0 -1641.25 -0.00940024693626206 -0.1205 -0.5096 1953569 Maybridge1_002424 CC1(CC1C(=O)NN)C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G05 compound treatment 972390.0 -102000.0 -0.5 975920.0 -49600.0 -0.29 944860.0 -92841.25 -0.531747555747899 -0.7659 -0.9729 1953570 Maybridge1_002425 O/N=C\1/CCCc2c1nc(c3ccccc3)n2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G06 compound treatment 830890.0 -244000.0 -1.19 787740.0 -238000.0 -1.41 869560.0 -168141.25 -0.963027735062771 -2.0601 -0.9882 1421027 Maybridge1_002426 Cc1cc(c(C)cc1Cl)S(=O)(=O)NC2C(C)(C)C3CCC2(C)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G07 compound treatment 1135960.0 61200.0 0.3 979920.0 -45600.0 -0.27 975330.0 -62371.25 -0.357230861674538 -0.19 -0.3526 1050913 Maybridge1_002427 Brc1ccc-2c(c1)C(=O)c3cc(Br)ccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G08 compound treatment 1177300.0 103000.0 0.5 1136660.0 111000.0 0.66 1065330.0 27628.75 0.158243456231683 0.7623 0.9027 1953571 Maybridge1_002428 Cc1ccc(OS(=O)(=O)c2cc(C)c(Cl)cc2C)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G09 compound treatment 1115680.0 40900.0 0.2 1224800.0 199000.0 1.19 1213480.0 175778.75 1.00677145842953 1.381 0.8808 1114550 Maybridge1_002429 COc1ccc(OC)c(NC(=O)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G10 compound treatment 956590.0 -118000.0 -0.58 995710.0 -29800.0 -0.18 955650.0 -82051.25 -0.469947912523365 -0.7068 -0.9238 1268749 Maybridge1_002430 COc1ccccc1N2CCN(Cc3ccc4ccccc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G11 compound treatment 1324870.0 250000.0 1.22 1047580.0 22100.0 0.13 1113460.0 75758.75 0.433907666463088 1.0319 0.7917 2112 Maybridge1_002431 OC(=O)CCc1c[nH]c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G12 compound treatment 1199960.0 125000.0 0.61 1159000.0 134000.0 0.79 1290330.0 252628.75 1.44692925099724 1.647 0.9357 1953572 Maybridge1_002432 Clc1ccc(cc1)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G13 compound treatment 1304050.0 229000.0 1.12 1291490.0 266000.0 1.58 1331420.0 293718.75 1.68227191458353 2.5313 0.9863 1953573 Maybridge1_002433 CC(=O)N[C@@H](CCCNC(=N)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G14 compound treatment 693600.0 -381000.0 -1.86 718170.0 -307000.0 -1.83 860610.0 -177091.25 -1.01428879223233 -2.7158 -0.9702 1937246 Maybridge1_002434 FC(F)(F)c1cc(n[nH]1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G15 compound treatment 1079800.0 5040.0 0.02 1297920.0 272000.0 1.62 1133940.0 96238.75 0.551206711248859 1.2678 0.7408 1277912 Maybridge1_002435 CC(=O)NC(C(=O)O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G16 compound treatment 872590.0 -202000.0 -0.99 818760.0 -207000.0 -1.23 770270.0 -267431.25 -1.53171045756176 -2.1643 -0.9845 1002852 Maybridge1_002436 Clc1cc(Cl)c(Cl)c(Cl)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G17 compound treatment 1319410.0 245000.0 1.2 1219870.0 194000.0 1.16 1288760.0 251058.75 1.43793708789598 2.1877 0.9952 1953574 Maybridge1_002437 C[C@]12CC(=O)C[C@]2(C)CC(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G18 compound treatment 1245000.0 170000.0 0.83 1311550.0 286000.0 1.7 1249370.0 211668.75 1.21233116142569 2.1623 0.9617 1953575 Maybridge1_002438 Cc1nc(no1)c2noc(C)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G19 compound treatment 1185230.0 110000.0 0.54 1078680.0 53200.0 0.32 1094940.0 57238.75 0.32783450682283 0.6836 0.9678 1953576 Maybridge1_002439 OC(=O)CNC1CCS(=O)(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G20 compound treatment 1289800.0 215000.0 1.05 1047530.0 22100.0 0.13 1274650.0 236948.75 1.35712216983313 1.4659 0.8516 1641870 Maybridge1_002440 OC1CC2CCC1C(C2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G21 compound treatment 1304870.0 230000.0 1.12 1191560.0 166000.0 0.99 1282410.0 244708.75 1.40156751102149 2.0285 0.9894 1123196 Maybridge1_002441 CC(C)(c1ccc(Oc2ccc(C(=O)O)c(c2)C(=O)O)cc1)c3ccc(Oc4ccc(C(=O)O)c(c4)C(=O)O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G22 compound treatment 1226960.0 152000.0 0.74 1028960.0 3490.0 0.02 1194980.0 157278.75 0.900812848637701 0.9614 0.8229 1025330 Maybridge1_002442 O=C(CCCCCCCCC(=O)c1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G23 mock treatment 1113490.0 38700.0 0.19 1048410.0 22900.0 0.14 1052900.0 15198.75 0.0870507254364131 0.2383 0.957 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 G24 mock treatment 1078480.0 3720.0 0.02 1117810.0 92300.0 0.55 1080290.0 42588.75 0.24392674285254 0.4683 0.7791 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H01 compound treatment 925280.0 -149000.0 -0.73 1117180.0 91700.0 0.55 1077020.0 39318.75 0.22519784263528 0.0232 0.0247 1953577 Maybridge1_002443 CCOC(=O)C1(CCCC2CCC1)OC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H02 compound treatment 1097600.0 22800.0 0.11 1021970.0 -3500.0 -0.02 1038430.0 728.75 0.00417391010193509 0.0548 0.4825 1953578 Maybridge1_002444 CCOc1ccccc1C=C2C(=O)NC(=S)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H03 compound treatment 543730.0 -531000.0 -2.59 555040.0 -470000.0 -2.8 506950.0 -530751.25 -3.03987376190693 -4.8681 -0.9979 1053130 Maybridge1_002445 BrC1(CC2CC3C1)CC(Br)(C2)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H04 compound treatment 706160.0 -369000.0 -1.8 658340.0 -367000.0 -2.18 678880.0 -358821.25 -2.05514598993342 -3.4868 -0.9969 1953579 Maybridge1_002446 CC(=O)CSc1nsc(SCC(=O)C)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H05 compound treatment 1052700.0 -22100.0 -0.11 1008800.0 -16700.0 -0.1 1041040.0 3338.75 0.0191226653212155 -0.1084 -0.7342 1953580 Maybridge1_002447 CC(C)(CC(=O)O)C(CCC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H06 compound treatment 1264430.0 190000.0 0.93 1296550.0 271000.0 1.61 1312020.0 274318.75 1.57115856161263 2.3728 0.9747 1953581 Maybridge1_002448 COc1ccc(CC/N=C/c2ccccn2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H07 compound treatment 1150650.0 75900.0 0.37 1055000.0 29500.0 0.18 1030310.0 -7391.25 -0.0423333283580484 0.291 0.7056 1052017 Maybridge1_002449 O=C1CC(=O)N2C=CC=CC2=N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H08 compound treatment 749440.0 -325000.0 -1.59 832110.0 -193000.0 -1.15 788270.0 -249431.25 -1.42861559398051 -2.4064 -0.9916 1953582 Maybridge1_002450 COc1ccccc1/C=C\2/C(=O)Nc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H09 compound treatment 1178720.0 104000.0 0.51 1032710.0 7240.0 0.04 1177940.0 140238.75 0.803216377780789 0.7818 0.8218 1953583 Maybridge1_002451 CC(C)(CCCCC(C)(C)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H10 compound treatment 826460.0 -248000.0 -1.21 786960.0 -239000.0 -1.42 777280.0 -260421.25 -1.49156073568928 -2.3804 -0.9963 1947495 Maybridge1_002452 COc1ccc(CCNC(=S)Nc2cccc(c2)C(F)(F)F)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H11 compound treatment 928900.0 -146000.0 -0.71 819370.0 -206000.0 -1.23 859360.0 -178341.25 -1.02144815775881 -1.7088 -0.9779 1953584 Maybridge1_002453 Brc1ccc2nc(cc(C#N)c2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H12 compound treatment 1212260.0 137000.0 0.67 1010600.0 -14900.0 -0.09 1051710.0 14008.75 0.0802350094552086 0.3831 0.5615 1953585 Maybridge1_002454 O=C(NNC(=S)NC1CC2CC1C=C2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H13 compound treatment 1153480.0 78700.0 0.38 1177610.0 152000.0 0.9 1130360.0 92658.75 0.530702288381034 1.0508 0.9406 1008402 Maybridge1_002455 OC(=O)c1cc2ccccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H14 compound treatment 925370.0 -149000.0 -0.73 1057240.0 31800.0 0.19 982570.0 -55131.25 -0.315763816545193 -0.4946 -0.6051 1953586 Maybridge1_002456 Cc1nn(C(=O)c2ccccc2Cl)c(C)c1N=Nc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H15 compound treatment 1042720.0 -32000.0 -0.16 1183530.0 158000.0 0.94 1048340.0 10638.75 0.0609333599958312 0.4874 0.5105 1953587 Maybridge1_002457 Cc1nn(nc1C(=O)O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H16 compound treatment 1221370.0 147000.0 0.72 1169440.0 144000.0 0.86 1105770.0 68068.75 0.389863249744212 1.1329 0.9582 1953588 Maybridge1_002458 Cc1csc(NC(=N)N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H17 compound treatment 951520.0 -123000.0 -0.6 1006360.0 -19100.0 -0.11 1161770.0 124068.75 0.710602825330305 -0.003 -0.0032 1953589 Maybridge1_002459 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H18 compound treatment 945080.0 -130000.0 -0.63 922280.0 -103000.0 -0.61 842760.0 -194941.25 -1.1165245319504 -1.3647 -0.9591 1953590 Maybridge1_002460 Cc1c(C)c(C)c(C(=O)c2ccc(cc2)[N+](=O)[O-])c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H19 compound treatment 368210.0 -707000.0 -3.45 429800.0 -596000.0 -3.54 467840.0 -569861.25 -3.26387599049929 -5.9226 -0.9994 1052210 Maybridge1_002461 O=C1NC(=O)C(=Cc2ccco2)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H20 compound treatment 1286520.0 212000.0 1.03 1266840.0 241000.0 1.44 1212580.0 174878.75 1.00161671525047 2.0043 0.9858 1953591 Maybridge1_002462 CC(OC(C)c1c(C)c(C)c(C)c(C)c1C)c2c(C)c(C)c(C)c(C)c2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H21 compound treatment 1278950.0 204000.0 1.0 1272120.0 247000.0 1.47 1182410.0 144708.75 0.828818268903465 1.9013 0.9711 1931378 Maybridge1_002463 COc1cccc(C=C2C(=O)NC(=S)NC2=O)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H22 compound treatment 931290.0 -143000.0 -0.7 813250.0 -212000.0 -1.26 770720.0 -266981.25 -1.52913308597223 -2.0162 -0.9587 1953592 Maybridge1_002464 CC(C)c1ccc(NN=C(C(=O)C)C(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H23 mock treatment 1112490.0 37700.0 0.18 1020180.0 -5290.0 -0.03 1020990.0 -16711.25 -0.0957135577234482 0.033 0.1571 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 H24 mock treatment 1121300.0 46500.0 0.23 997440.0 -28000.0 -0.17 1003320.0 -34381.25 -0.196918348805703 -0.0787 -0.2287 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I01 compound treatment 881150.0 -194000.0 -0.95 1029120.0 3650.0 0.02 1011390.0 -26311.25 -0.150697484966778 -0.6206 -0.6478 1953593 Maybridge1_002465 CC1CN=C(Nc2cccc(C)c2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I02 compound treatment 1044380.0 -30400.0 -0.15 988580.0 -36900.0 -0.22 893770.0 -143931.25 -0.824365143545997 -0.6883 -0.7949 1953594 Maybridge1_002466 OC(=O)[C@@H]1Cc2ccccc2N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I03 compound treatment 1002200.0 -72600.0 -0.35 918780.0 -107000.0 -0.63 995680.0 -42021.25 -0.24067639090352 -0.7099 -0.9273 1953595 Maybridge1_002467 Cc1cccc(NC2=NCC(C)(C)S2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I04 compound treatment 1074900.0 139.0 0.0 936640.0 -88800.0 -0.53 1046820.0 9118.75 0.0522275715156372 -0.2744 -0.517 1953596 Maybridge1_002468 O=C(NC(C(/N=C/c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I05 compound treatment 657380.0 -417000.0 -2.04 839490.0 -186000.0 -1.11 883710.0 -153991.25 -0.88198371730307 -2.3251 -0.9368 1953597 Maybridge1_002469 CCCCCCC(=O)c1ccc(Br)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I06 compound treatment 946400.0 -128000.0 -0.63 915910.0 -110000.0 -0.65 1020360.0 -17341.25 -0.0993218779487917 -0.7956 -0.8745 1674947 Maybridge1_002470 CC1(C)C(NS(=O)(=O)c2ccc(C#N)cc2)C3(C)CCC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I07 compound treatment 565810.0 -509000.0 -2.49 569400.0 -456000.0 -2.71 581010.0 -456691.25 -2.61569567319433 -4.5117 -0.9994 1953598 Maybridge1_002471 CCCCCc1ccc(CN)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I08 compound treatment 1214790.0 140000.0 0.68 1118440.0 93000.0 0.55 1097280.0 59578.75 0.341236839088392 0.9112 0.9658 1953599 Maybridge1_002472 Cc1ccc(OS(=O)(=O)c2ccc(Cl)cc2)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I09 compound treatment 1162840.0 88100.0 0.43 1065540.0 40100.0 0.24 1021320.0 -16381.25 -0.0938234852244587 0.3318 0.6627 1004835 Maybridge1_002473 CC(=O)CC(=O)Nc1ccccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I10 compound treatment 696200.0 -379000.0 -1.85 729510.0 -296000.0 -1.76 708110.0 -329591.25 -1.88773138646232 -3.1739 -0.9996 1256986 Maybridge1_002474 COc1ccccc1C2CCN(Cc3ccc(Cl)cc3Cl)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I11 compound treatment 1090530.0 15800.0 0.08 1013880.0 -11600.0 -0.07 1138090.0 100388.75 0.574975804796757 0.3366 0.5762 1914379 Maybridge1_002475 CCSc1nc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I12 compound treatment 1151380.0 76600.0 0.37 1083950.0 58500.0 0.35 981650.0 -56051.25 -0.321033109572679 0.2315 0.3837 1953600 Maybridge1_002476 O=S(=O)(Oc1ccc(Oc2ccccc2)cc1)c3ccc(C#N)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I13 compound treatment 1196920.0 122000.0 0.6 1244720.0 219000.0 1.3 1238080.0 200378.75 1.14766777199057 1.7599 0.9582 1081511 Maybridge1_002477 CC(=O)NC(CC(=O)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I14 compound treatment 1195540.0 121000.0 0.59 1090950.0 65500.0 0.39 1137180.0 99478.75 0.569763786693483 0.8945 0.9851 1238971 Maybridge1_002478 CC1(C)C(CCC1(C)C(=O)N2CCCCC2)C(=O)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I15 compound treatment 1051640.0 -23100.0 -0.11 966520.0 -59000.0 -0.35 1039170.0 1468.75 0.00841225449360847 -0.2628 -0.7132 3115140 Maybridge1_002479 C[C@@H](N)C(=O)OCc1ccccc1.Cc1ccc(cc1)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I16 compound treatment 1290810.0 216000.0 1.06 992040.0 -33400.0 -0.2 1191360.0 153658.75 0.880079326073028 1.0028 0.7221 1953602 Maybridge1_002480 Cc1c(Br)c(Br)c(Br)c(Br)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I17 compound treatment 969030.0 -106000.0 -0.52 967380.0 -58100.0 -0.35 998590.0 -39111.25 -0.224009387957885 -0.627 -0.9492 1953603 Maybridge1_002481 COc1cc(I)c(OC)cc1I 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I18 compound treatment 1158950.0 84200.0 0.41 1139620.0 114000.0 0.68 1215730.0 178028.75 1.01965831637719 1.2181 0.9427 1017720 Maybridge1_002482 OCC1CCCN2CCCCC12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I19 compound treatment 1091090.0 16300.0 0.08 974420.0 -51100.0 -0.3 1138520.0 100818.75 0.577438626537865 0.2042 0.3106 1953604 Maybridge1_002483 ClC1=CCS(=O)(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I20 compound treatment 1310150.0 235000.0 1.15 1079360.0 53900.0 0.32 1229600.0 191898.75 1.09909863625896 1.4836 0.9142 1953605 Maybridge1_002484 COC1(C/C=C\CC(C/C=C\C1)(OC)OC)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I21 compound treatment 1094450.0 19700.0 0.1 1037760.0 12300.0 0.07 1041090.0 3388.75 0.0194090399422745 0.1089 0.8903 1017948 Maybridge1_002485 OC1(CCCCC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I22 compound treatment 1309400.0 235000.0 1.15 1128660.0 103000.0 0.61 1319770.0 282068.75 1.61554662787678 1.9489 0.9398 1604709 Maybridge1_002486 OC1CC2CCC1N(Cc3ccccc3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I23 mock treatment 1096450.0 21700.0 0.11 1020360.0 -5110.0 -0.03 1109930.0 72228.75 0.413689618216322 0.2825 0.6598 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 I24 mock treatment 1077570.0 2810.0 0.01 985810.0 -39700.0 -0.24 1022080.0 -15621.25 -0.0894705909843617 -0.1799 -0.7121 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J01 compound treatment 918800.0 -156000.0 -0.76 929610.0 -95900.0 -0.57 951200.0 -86501.25 -0.495435253797617 -1.0551 -0.9834 1016032 Maybridge1_002487 COC(=O)C1CC2(CC(CC(C(=O)OC)C2=O)(C(=O)OC)C1=O)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J02 compound treatment 636640.0 -438000.0 -2.14 548220.0 -477000.0 -2.84 523040.0 -514661.25 -2.94771840885014 -4.5763 -0.991 1953606 Maybridge1_002488 COc1ccc(OC)c(/C=C\2/C(=O)Nc3ccccc23)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J03 compound treatment 991760.0 -83000.0 -0.41 1068850.0 43400.0 0.26 1082590.0 44888.75 0.257099975421254 0.0632 0.116 1100808 Maybridge1_002489 CCOC(=O)C1(CCC2(CC31SCCS3)C(=O)OCC)CC42SCCS4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J04 compound treatment 588340.0 -486000.0 -2.38 557600.0 -468000.0 -2.78 471270.0 -566431.25 -3.24423069149465 -4.8515 -0.9921 1953607 Maybridge1_002490 COc1ccc(Br)cc1/C=C\2/C(=O)Nc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J05 compound treatment 1129280.0 54500.0 0.27 1020990.0 -4480.0 -0.03 1000890.0 -36811.25 -0.210836155389171 0.0167 0.0489 1953608 Maybridge1_002491 COC(=O)CCC(CCC(=O)OC)(C(=O)C)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J06 compound treatment 1144760.0 70000.0 0.34 1071330.0 45900.0 0.27 1087200.0 49498.75 0.283503715482895 0.5186 0.9949 1953609 Maybridge1_002492 Fc1cccc(F)c1C(=O)NCCCNC(=O)c2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J07 compound treatment 34330.0 -1040000.0 -5.08 42180.0 -983000.0 -5.85 48290.0 -989411.25 -5.66684543580546 -9.5825 -0.9983 1953610 Maybridge1_002493 CCCCCCCCCCCCCC#CC(O)C(N)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J08 compound treatment 956160.0 -119000.0 -0.58 931360.0 -94100.0 -0.56 930410.0 -107291.25 -0.614509821233954 -1.0125 -0.9992 1953611 Maybridge1_002494 CN(CCC#N)c1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J09 compound treatment 1054920.0 -19800.0 -0.1 1119110.0 93600.0 0.56 952860.0 -84841.25 -0.485927616378457 -0.015 -0.0202 1322271 Maybridge1_002495 OC1(CC(=O)c2ccc3OCOc3c2)C(=O)Nc4ccc(Br)cc41 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J10 compound treatment 776700.0 -298000.0 -1.46 779220.0 -246000.0 -1.46 784880.0 -252821.25 -1.44803179328831 -2.5222 -1.0 1953612 Maybridge1_002496 Cc1c(C)c(C)c(CNC(=O)c2ccccc2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J11 compound treatment 1309210.0 234000.0 1.15 1079330.0 53900.0 0.32 1303040.0 265338.75 1.51972567967044 1.7237 0.8932 1953613 Maybridge1_002497 OC(=O)c1ccc2OCCc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J12 compound treatment 1188410.0 114000.0 0.56 999040.0 -26400.0 -0.16 1054740.0 17038.75 0.0975893114913847 0.2862 0.489 1953614 Maybridge1_002498 O=C(NNC(=S)NC1CC2CC1C=C2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J13 compound treatment 1380600.0 306000.0 1.49 951730.0 -73700.0 -0.44 1160400.0 122698.75 0.702756160713288 1.0153 0.5942 1953615 Maybridge1_002499 Cc1cc(C(=O)O)c(C)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J14 compound treatment 1198920.0 124000.0 0.61 1207760.0 182000.0 1.08 1244640.0 206938.75 1.18524012227351 1.6604 0.9671 1059435 Maybridge1_002500 COc1cc(CC(=O)O)c(cc1OC)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J15 compound treatment 1133240.0 58500.0 0.29 1074940.0 49500.0 0.29 1087580.0 49878.75 0.285680162602943 0.4997 0.9999 1452607 Maybridge1_002501 OC(=O)c1ccc2[nH]nnc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J16 compound treatment 1171480.0 96700.0 0.47 1037280.0 11800.0 0.07 1134260.0 96558.75 0.553039508823637 0.6327 0.8657 1953616 Maybridge1_002502 COc1cc(cc(OC)c1OC)C(=O)NN(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J17 compound treatment 56480.0 -1020000.0 -4.98 63170.0 -962000.0 -5.72 75040.0 -962661.25 -5.51363501353889 -9.3595 -0.9983 1953617 Maybridge1_002503 CCNC(=N)SCc1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J18 compound treatment 207420.0 -867000.0 -4.24 248070.0 -777000.0 -4.62 243570.0 -794131.25 -4.54838071579738 -7.7417 -0.9993 1953618 Maybridge1_002504 Oc1c(Cl)cc(Cl)cc1/C=N/NC(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J19 compound treatment 557790.0 -517000.0 -2.53 547540.0 -478000.0 -2.84 583850.0 -453851.25 -2.59942959471817 -4.5999 -0.9987 1953619 Maybridge1_002505 COc1ccc(Br)cc1C=C2C(=O)NC(=O)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J20 compound treatment 657330.0 -417000.0 -2.04 648770.0 -377000.0 -2.24 684960.0 -352741.25 -2.02032283601264 -3.6373 -0.9989 1060626 Maybridge1_002506 COc1ccc(cc1)C(=C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J21 compound treatment 1247140.0 172000.0 0.84 1090160.0 64700.0 0.38 1258170.0 220468.75 1.26273309473208 1.4374 0.918 1953620 Maybridge1_002507 CCOc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J22 compound treatment 1196770.0 122000.0 0.6 1168080.0 143000.0 0.85 1128480.0 90778.75 0.519934602629215 1.134 0.9778 1953621 Maybridge1_002508 Fc1ccc(NC(=O)C2CCC2)cc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J23 mock treatment 1060850.0 -13900.0 -0.07 1050780.0 25300.0 0.15 1043040.0 5338.75 0.030577650163576 0.0653 0.3888 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 J24 mock treatment 1041480.0 -33300.0 -0.16 1040600.0 15100.0 0.09 981990.0 -55711.25 -0.319085762149477 -0.2262 -0.6125 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K01 compound treatment 1004410.0 -70400.0 -0.34 1040320.0 14800.0 0.09 1026290.0 -11411.25 -0.0653578478911929 -0.1852 -0.5133 1938018 Maybridge1_002509 CC1CN=C(Nc2ccccc2C)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K02 compound treatment 1024440.0 -50300.0 -0.25 1024290.0 -1180.0 -0.01 1059590.0 21888.75 0.125367649734109 -0.0736 -0.2667 1168019 Maybridge1_002510 CC(=O)OC1CC2CCC1N(Cc3ccccc3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K03 compound treatment 950820.0 -124000.0 -0.61 1026920.0 1450.0 0.01 971370.0 -66331.25 -0.379911731662411 -0.564 -0.7889 1953622 Maybridge1_002511 CCOC(=O)C(O)(c1ccc(N)cc1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K04 compound treatment 1063790.0 -11000.0 -0.05 1057920.0 32400.0 0.19 974680.0 -63021.25 -0.360953731748305 -0.1279 -0.31 1953623 Maybridge1_002512 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K05 compound treatment 1049500.0 -25300.0 -0.12 1000880.0 -24600.0 -0.15 1010190.0 -27511.25 -0.157570475872195 -0.2467 -0.9951 1278482 Maybridge1_002513 OC(=O)CCCc1ccc2OCCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K06 compound treatment 1047040.0 -27700.0 -0.14 952910.0 -72600.0 -0.43 1154570.0 116868.75 0.669364879897807 0.0591 0.0732 1738476 Maybridge1_002514 CC1(C)C(NC(=O)c2cccs2)C3(C)CCC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K07 compound treatment 1152740.0 78000.0 0.38 1045490.0 20000.0 0.12 1066770.0 29068.75 0.166491045318183 0.3848 0.8898 1917345 Maybridge1_002515 CCN(c1ccccc1)S(=O)(=O)c2cc(ccc2N)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K08 compound treatment 1283700.0 209000.0 1.02 1082090.0 56600.0 0.34 1107040.0 69338.75 0.397137165119111 1.013 0.884 1953624 Maybridge1_002516 Cc1ccc(OS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K09 compound treatment 1095470.0 20700.0 0.1 1100760.0 75300.0 0.45 1070310.0 32608.75 0.186766368489161 0.4247 0.8571 1038041 Maybridge1_002517 CC(=O)CC(=O)NCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K10 compound treatment 629790.0 -445000.0 -2.17 636760.0 -389000.0 -2.31 639790.0 -397911.25 -2.27903366867735 -3.9055 -0.9997 1246691 Maybridge1_002518 COc1ccccc1C2CCN(Cc3ccc(Cl)c(Cl)c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K11 compound treatment 1128640.0 53900.0 0.26 1035750.0 10300.0 0.06 964990.0 -72711.25 -0.416453133309541 -0.0532 -0.1071 1300359 Maybridge1_002519 O=C(CC(Nc1ccccc1)c2ccccc2)C3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K12 compound treatment 1203240.0 128000.0 0.63 1240510.0 215000.0 1.28 1157410.0 119708.75 0.685630958373959 1.4965 0.9466 1953625 Maybridge1_002520 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K13 compound treatment 1059550.0 -15200.0 -0.07 1014560.0 -10900.0 -0.06 1107370.0 69668.75 0.3990272376181 0.15 0.3649 1007394 Maybridge1_002521 CC(=O)NC(CCC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K14 compound treatment 546490.0 -528000.0 -2.58 260930.0 -765000.0 -4.55 251410.0 -786291.25 -4.50347717521533 -6.7151 -0.9732 1953626 Maybridge1_002522 CC1(C)C/2CCC1(C)C(=O)\C2=C/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K15 compound treatment 1001700.0 -73100.0 -0.36 954320.0 -71200.0 -0.42 1008010.0 -29691.25 -0.170056409350368 -0.5486 -0.9472 1083802 Maybridge1_002523 Cc1ccc2nc(sc2c1S(=O)(=O)O)c3ccc(N)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K16 compound treatment 707590.0 -367000.0 -1.79 706720.0 -319000.0 -1.9 719200.0 -318501.25 -1.82421349551143 -3.1833 -0.9997 1953627 Maybridge1_002524 FC(F)(F)c1n[nH]c2CCCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K17 compound treatment 1042830.0 -31900.0 -0.16 1099730.0 74300.0 0.44 1098880.0 61178.75 0.35040082696228 0.3672 0.6278 1953628 Maybridge1_002525 CC(=CCC(CC=C(C)C)(C#N)C(=O)O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K18 compound treatment 1062560.0 -12200.0 -0.06 1077660.0 52200.0 0.31 1118240.0 80538.75 0.461285080236329 0.4111 0.7352 1633817 Maybridge1_002526 CCOC(=O)C1CC2CN(CC(C1)C2=O)S(=O)(=O)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K19 compound treatment 1113120.0 38400.0 0.19 993210.0 -32300.0 -0.19 1079110.0 41408.75 0.237168301795547 0.1344 0.3753 1420628 Maybridge1_002527 CS(=O)(=O)C1CS(=O)(=O)CC1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K20 compound treatment 1016610.0 -58200.0 -0.28 1005410.0 -20100.0 -0.12 951940.0 -85761.25 -0.491196909405943 -0.5165 -0.8908 1057505 Maybridge1_002528 OC(=O)C1CC2CCC1CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K21 compound treatment 1197080.0 122000.0 0.6 1120690.0 95200.0 0.57 1084680.0 46978.75 0.269070434581521 0.8273 0.9552 1055897 Maybridge1_002529 O=C(N1CCC(=O)CC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K22 compound treatment 1103200.0 28400.0 0.14 1000640.0 -24800.0 -0.15 1077320.0 39618.75 0.226916090361634 0.126 0.414 1953629 Maybridge1_002530 COC(=O)CCC(CCC(=O)OC)(C(=O)OC)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K23 mock treatment 1103040.0 28300.0 0.14 979630.0 -45800.0 -0.27 1066040.0 28338.75 0.162309975850721 0.0161 0.0465 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 K24 mock treatment 1157090.0 82300.0 0.4 1073800.0 48300.0 0.29 1057920.0 20218.75 0.115802737390738 0.465 0.9159 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L01 compound treatment 441400.0 -633000.0 -3.09 417850.0 -608000.0 -3.61 405120.0 -632581.25 -3.62310431515572 -5.9645 -0.9974 1953630 Maybridge1_002531 O/N=C(\CNC(c1ccccc1)(c2ccccc2)c3ccccc3)/c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L02 compound treatment 775140.0 -300000.0 -1.46 733880.0 -292000.0 -1.73 737200.0 -300501.25 -1.72111863193019 -2.84 -0.9971 1378376 Maybridge1_002532 COc1cccc(NC(=S)Nc2ccc(O)cc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L03 compound treatment 1108700.0 33900.0 0.17 924010.0 -101000.0 -0.6 964500.0 -73201.25 -0.419259604595919 -0.4947 -0.6568 1077130 Maybridge1_002533 OC1CC2CCC1C2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L04 compound treatment 96180.0 -979000.0 -4.78 137870.0 -888000.0 -5.28 117210.0 -920491.25 -5.27210665813772 -8.8516 -0.999 1083326 Maybridge1_002534 CSC(=C(C#N)C#N)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L05 compound treatment 960890.0 -114000.0 -0.56 977600.0 -47900.0 -0.28 1049090.0 11388.75 0.0652289793117164 -0.4479 -0.7128 1953631 Maybridge1_002535 CC1(C)C2C1C3(CO)CCC2CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L06 compound treatment 39150.0 -1040000.0 -5.06 44250.0 -981000.0 -5.83 53180.0 -984521.25 -5.63883799786589 -9.5457 -0.9982 1953632 Maybridge1_002536 Clc1cc(Cl)cc(c1)N2C(=O)C=CC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L07 compound treatment 1052890.0 -21900.0 -0.11 957960.0 -67500.0 -0.4 1185490.0 147788.75 0.8464589455607 0.1952 0.207 1953633 Maybridge1_002537 O=C1OCC2(CCC3CC12)C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L08 compound treatment 1056680.0 -18100.0 -0.09 904910.0 -121000.0 -0.72 928380.0 -109321.25 -0.626136630848949 -0.8264 -0.8645 1953634 Maybridge1_002538 COc1cc(/C=N/CCCN2CCN(CCC\N=C\c3cc(OC)c(OC)c(OC)c3)CC2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L09 compound treatment 728410.0 -346000.0 -1.69 701370.0 -324000.0 -1.93 739840.0 -297861.25 -1.70599805193827 -3.0747 -0.9982 1953635 Maybridge1_002539 OC1(CC(=O)c2cccc(c2)[N+](=O)[O-])C(=O)Nc3ccc(Br)cc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L10 compound treatment 1103520.0 28800.0 0.14 955370.0 -70100.0 -0.42 951770.0 -85931.25 -0.492170583117544 -0.4437 -0.6722 1953636 Maybridge1_002540 CC(=O)/C(=N\O)/c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L11 compound treatment 963150.0 -112000.0 -0.55 848240.0 -177000.0 -1.05 812830.0 -224871.25 -1.28794838011633 -1.6669 -0.9518 1953637 Maybridge1_002541 Ic1ccc2OCCc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L12 compound treatment 891790.0 -183000.0 -0.89 887360.0 -138000.0 -0.82 977190.0 -60511.25 -0.346577725771142 -1.1904 -0.9429 1953638 Maybridge1_002542 O=C(NNC(=S)NC1CC2CC1C=C2)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L13 compound treatment 1203320.0 129000.0 0.63 1017520.0 -7950.0 -0.05 1051850.0 14148.75 0.0810368583941738 0.3821 0.6017 1953639 Maybridge1_002543 OC(=O)c1ccc2snnc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L14 compound treatment 1252890.0 178000.0 0.87 1068160.0 42700.0 0.25 1134930.0 97228.75 0.556876928745828 0.9705 0.9122 1087077 Maybridge1_002544 COC(=O)Cc1cc(OC)c(OC)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L15 compound treatment 1024090.0 -50700.0 -0.25 972110.0 -53400.0 -0.32 1052400.0 14698.75 0.0841869792258229 -0.2775 -0.675 1004346 Maybridge1_002545 Cc1c(C)c(C)c(Br)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L16 compound treatment 766910.0 -308000.0 -1.5 773530.0 -252000.0 -1.5 683000.0 -354701.25 -2.03154872115815 -2.9063 -0.9891 1953640 Maybridge1_002546 CCOC(=O)CSCc1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L17 compound treatment 132610.0 -942000.0 -4.6 429070.0 -596000.0 -3.55 225920.0 -811781.25 -4.64947095703122 -7.3896 -0.9929 1953641 Maybridge1_002547 Cc1c(C)c(C)c(CSC(=N)Nc2ccccc2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L18 compound treatment 924970.0 -150000.0 -0.73 1008270.0 -17200.0 -0.1 942400.0 -95301.25 -0.545837187104003 -0.7967 -0.8672 1953642 Maybridge1_002548 S=C(N/N=C/C=C/c1ccccc1)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L19 compound treatment 1081280.0 6520.0 0.03 1020670.0 -4800.0 -0.03 1025040.0 -12661.25 -0.0725172134176682 -0.04 -0.4747 1953643 Maybridge1_002549 N#Cc1ccc(CSC2=NCCCN2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L20 compound treatment 1205960.0 131000.0 0.64 1080480.0 55000.0 0.33 1035490.0 -2211.25 -0.0126649176163348 0.5516 0.7664 1953644 Maybridge1_002550 Cc1c(C)c(C)c(C(=O)c2ccc(Cl)cc2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L21 compound treatment 1160930.0 86200.0 0.42 1017050.0 -8420.0 -0.05 1137380.0 99678.75 0.570909285177719 0.5438 0.7647 1953645 Maybridge1_002551 CC(=O)Nc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L22 compound treatment 1088930.0 14200.0 0.07 1093320.0 67800.0 0.4 1138400.0 100698.75 0.576751327447323 0.6059 0.8567 1953646 Maybridge1_002552 CC(C)c1ccc(NN=C2C(=O)NC(=O)NC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L23 mock treatment 1079320.0 4560.0 0.02 968570.0 -56900.0 -0.34 1062790.0 25088.75 0.143695625481886 -0.0995 -0.2703 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 L24 mock treatment 1117880.0 43100.0 0.21 956280.0 -69200.0 -0.41 944640.0 -93061.25 -0.533007604080559 -0.4237 -0.6005 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M01 compound treatment 972040.0 -103000.0 -0.5 951330.0 -74100.0 -0.44 895840.0 -141861.25 -0.812509234234154 -1.0134 -0.9634 1953647 Maybridge1_002553 CC1CN=C(NC2CCCCC2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M02 compound treatment 316210.0 -759000.0 -3.71 298880.0 -727000.0 -4.32 296180.0 -741521.25 -4.24705733951909 -7.0864 -0.9978 1953648 Maybridge1_002554 Nc1cc(c(N)c2C(=O)c3ccccc3C(=O)c12)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M03 compound treatment 983160.0 -91600.0 -0.45 948480.0 -77000.0 -0.46 994740.0 -42961.25 -0.246060233779429 -0.6648 -0.9692 1953649 Maybridge1_002555 CCOC(=O)C(O)(c1ccc(NC)cc1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M04 compound treatment 960000.0 -115000.0 -0.56 861170.0 -164000.0 -0.98 938580.0 -99121.25 -0.567716208152911 -1.2156 -0.9636 1953650 Maybridge1_002556 Cc1cc(c(C)cc1Cl)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M05 compound treatment 882330.0 -192000.0 -0.94 908830.0 -117000.0 -0.69 871160.0 -166541.25 -0.953863747188882 -1.494 -0.9905 1077614 Maybridge1_002557 NC(=O)c1cccc2C(=O)c3ccccc3-c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M06 compound treatment 939840.0 -135000.0 -0.66 996420.0 -29100.0 -0.17 978050.0 -59651.25 -0.341652082288927 -0.6776 -0.8889 1333748 Maybridge1_002558 CC1(C)C(NC(=O)c2ccc(Cl)cc2)C3(C)CCC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M07 compound treatment 966640.0 -108000.0 -0.53 916410.0 -109000.0 -0.65 948240.0 -89461.25 -0.51238863136431 -0.9753 -0.9942 1281100 Maybridge1_002559 CCNc1cc(NC(=O)C)ccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M08 compound treatment 1150830.0 76100.0 0.37 1149930.0 124000.0 0.74 1198430.0 160728.75 0.920572697490772 1.1734 0.9476 1953651 Maybridge1_002560 Cc1ccc(OS(=O)(=O)c2ccc(C#N)cc2)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M09 compound treatment 1012670.0 -62100.0 -0.3 965890.0 -59600.0 -0.35 972020.0 -65681.25 -0.376188861588644 -0.5969 -0.9961 1561783 Maybridge1_002561 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M10 compound treatment 928110.0 -147000.0 -0.72 831460.0 -194000.0 -1.15 899170.0 -138531.25 -0.793436684471624 -1.5379 -0.9777 1953652 Maybridge1_002562 COc1ccccc1C2CCN(Cc3cccc(c3)[N+](=O)[O-])CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M11 compound treatment 34880.0 -1040000.0 -5.08 48740.0 -977000.0 -5.81 55120.0 -982581.25 -5.6277266625688 -9.5359 -0.9984 1006159 Maybridge1_002563 ClC1=C(Cl)C(=O)c2ccccc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M12 compound treatment 1136210.0 61400.0 0.3 1028020.0 2550.0 0.02 1069280.0 31578.75 0.180867051295345 0.2865 0.8167 1953653 Maybridge1_002564 Clc1cccc(c1Cl)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M13 compound treatment 1097250.0 22500.0 0.11 1217250.0 192000.0 1.14 1291680.0 253978.75 1.45466136576583 1.5617 0.8434 1231 Maybridge1_002565 CC(C)C[C@H](NC(=O)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M14 compound treatment 996420.0 -78300.0 -0.38 925960.0 -99500.0 -0.59 951730.0 -85971.25 -0.492399682814391 -0.8469 -0.9851 1953654 Maybridge1_002566 Nc1nc(cc(n1)C(F)(F)F)c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M15 compound treatment 934450.0 -140000.0 -0.69 935920.0 -89600.0 -0.53 945170.0 -92531.25 -0.529972033097333 -1.0092 -0.9923 1953655 Maybridge1_002567 Cc1cc(I)c(C)cc1I 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M16 compound treatment 956130.0 -119000.0 -0.58 908180.0 -117000.0 -0.7 945030.0 -92671.25 -0.530773882036299 -1.0438 -0.9933 1953656 Maybridge1_002568 Nc1nc(c2CCCCc2n1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M17 compound treatment 721920.0 -353000.0 -1.72 763860.0 -262000.0 -1.56 739540.0 -298161.25 -1.70771629966462 -2.8794 -0.999 1953657 Maybridge1_002569 Clc1cccc(Cl)c1C(=O)O/N=C/2\CCCc3[nH]c4ccccc4c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M18 compound treatment 1039420.0 -35300.0 -0.17 996800.0 -28700.0 -0.17 1003150.0 -34551.25 -0.197892022517304 -0.3124 -0.9976 1953658 Maybridge1_002570 CC(C)CC1(C/C(=N/NC(=O)N)/C)CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M19 compound treatment 1069560.0 -5200.0 -0.03 1061600.0 36100.0 0.21 1092910.0 55208.75 0.316207697207834 0.2919 0.762 362 Maybridge1_002571 CCN(CC)CC(=O)Nc1c(C)cccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M20 compound treatment 1074660.0 -101.0 0.0 1017640.0 -7830.0 -0.05 1043080.0 5378.75 0.0308067498604232 -0.0094 -0.1681 1953659 Maybridge1_002572 COC(=O)C1CCC(NC(=O)C)C(C1)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M21 compound treatment 930690.0 -144000.0 -0.7 1025860.0 387.0 0.0 1058640.0 20938.75 0.119926531933988 -0.3358 -0.4703 1953660 Maybridge1_002573 COC(=O)c1cnc(NNS(=O)(=O)c2ccccc2)nc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M22 compound treatment 1056840.0 -17900.0 -0.09 958790.0 -66700.0 -0.4 1193010.0 155308.75 0.889529688567975 0.2341 0.2394 1189123 Maybridge1_002574 COC(=O)C1CCC(=C(C1)C(=O)OC)NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M23 mock treatment 950000.0 -125000.0 -0.61 1027450.0 1980.0 0.01 961410.0 -76291.25 -0.436957556177366 -0.5974 -0.7965 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 M24 mock treatment 1054820.0 -19900.0 -0.1 993070.0 -32400.0 -0.19 927390.0 -110311.25 -0.631806848345918 -0.5323 -0.7972 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N01 compound treatment 866830.0 -208000.0 -1.02 890010.0 -135000.0 -0.81 981800.0 -55901.25 -0.320173985709501 -1.2365 -0.9259 1953661 Maybridge1_002575 CC1(C)CC2(CCCCC2)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N02 compound treatment 145490.0 -929000.0 -4.54 119590.0 -906000.0 -5.39 167210.0 -870491.25 -4.98573203707871 -8.61 -0.9976 1953662 Maybridge1_002576 FC(F)(F)c1cccc(NC(=S)Nc2cccc(c2)C(F)(F)F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N03 compound treatment 1046890.0 -27900.0 -0.14 910880.0 -115000.0 -0.68 970240.0 -67461.25 -0.386383798098345 -0.6951 -0.8743 1196220 Maybridge1_002577 OC(=O)C1CC2(COC(OC2)c3ccccc3)C1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N04 compound treatment 64640.0 -1010000.0 -4.94 92080.0 -933000.0 -5.55 133570.0 -904131.25 -5.17840488212721 -9.0437 -0.9988 1054980 Maybridge1_002578 O=C1NC(=O)C(=Cc2cccs2)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N05 compound treatment 1044560.0 -30200.0 -0.15 1057960.0 32500.0 0.19 982350.0 -55351.25 -0.317023864877852 -0.1567 -0.3922 1195740 Maybridge1_002579 COC(=O)C1CCC(=C(C1)C(=O)OC)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N06 compound treatment 783390.0 -291000.0 -1.42 969630.0 -55800.0 -0.33 910620.0 -127081.25 -0.72785689624911 -1.4339 -0.8781 1953663 Maybridge1_002580 Clc1cccc(Cl)c1OC(=O)/C=C/c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N07 compound treatment 1010180.0 -64600.0 -0.32 933840.0 -91600.0 -0.54 1003420.0 -34281.25 -0.196345599563585 -0.6101 -0.925 1953664 Maybridge1_002581 CCC1(CC2CC3CC(Br)(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N08 compound treatment 618320.0 -456000.0 -2.23 692860.0 -333000.0 -1.98 666560.0 -371141.25 -2.12570869656236 -3.6568 -0.9988 1335256 Maybridge1_002582 Clc1ccc(CC2C(=O)Nc3ccccc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N09 compound treatment 450630.0 -624000.0 -3.05 160450.0 -865000.0 -5.14 176890.0 -860811.25 -4.93028991044168 -7.5769 -0.9776 1316548 Maybridge1_002583 OC1(CC(=O)c2ccc(cc2)c3ccccc3)C(=O)Nc4ccc(Br)cc41 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N10 compound treatment 1000900.0 -73900.0 -0.36 1017310.0 -8160.0 -0.05 1050490.0 12788.75 0.0732474687013687 -0.1941 -0.5226 1084499 Maybridge1_002584 O=C1N2CCCNC2c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N11 compound treatment 1098650.0 23900.0 0.12 972660.0 -52800.0 -0.31 994080.0 -43621.25 -0.249840378777408 -0.2582 -0.6177 1223785 Maybridge1_002585 OC(=O)C1COc2ccccc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N12 compound treatment 885140.0 -190000.0 -0.93 852590.0 -173000.0 -1.03 854760.0 -182941.25 -1.04779462289624 -1.7334 -0.9986 1953665 Maybridge1_002586 COc1ccccc1NC(=S)NNC(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N13 compound treatment 1294080.0 219000.0 1.07 1146980.0 122000.0 0.72 1155680.0 117978.75 0.675722396485317 1.426 0.9778 1953666 Maybridge1_002587 OC(=O)c1ccc2nonc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N14 compound treatment 1012030.0 -62700.0 -0.31 961760.0 -63700.0 -0.38 919200.0 -118501.25 -0.678715011275384 -0.7876 -0.9426 1517484 Maybridge1_002588 CCOC(=O)C1CCN(CC1)C(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N15 compound treatment 1095310.0 20500.0 0.1 1015590.0 -9880.0 -0.06 1216990.0 179288.75 1.02687495682788 0.6169 0.5969 1062106 Maybridge1_002589 Cc1c(C)c(C)c(Cc2c(C)c(C)c(C)c(C)c2C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N16 compound treatment 1000330.0 -74400.0 -0.36 1000160.0 -25300.0 -0.15 877450.0 -160251.25 -0.917837819859659 -0.8268 -0.8279 1953667 Maybridge1_002590 Cc1c(C)c(C)c(C(=O)c2ccccc2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N17 compound treatment 1100070.0 25300.0 0.12 1029480.0 4010.0 0.02 1072990.0 35288.75 0.202116048177924 0.2018 0.8476 1080236 Maybridge1_002591 CC1CCN(CC1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N18 compound treatment 1001160.0 -73600.0 -0.36 923220.0 -102000.0 -0.61 990880.0 -46821.25 -0.268168354525185 -0.7135 -0.9443 1953668 Maybridge1_002592 COc1ccc(OCCC(=O)NNC(=S)Nc2cccc(OC)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N19 compound treatment 1087880.0 13100.0 0.06 1027970.0 2500.0 0.01 1114260.0 76558.75 0.438489660400032 0.2987 0.6738 1953669 Maybridge1_002593 O=C(CSc1nsc(SCC(=O)c2ccccc2)c1C#N)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N20 compound treatment 1079160.0 4400.0 0.02 1064880.0 39400.0 0.23 1095310.0 57608.75 0.329953679018667 0.3382 0.8345 1953670 Maybridge1_002594 CN(C)c1ccc(cc1)C(=O)NNC(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N21 compound treatment 601120.0 -474000.0 -2.31 578640.0 -447000.0 -2.66 593610.0 -444091.25 -2.54352926868746 -4.3387 -0.9984 1928357 Maybridge1_002595 Oc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N22 compound treatment 953000.0 -122000.0 -0.59 973070.0 -52400.0 -0.31 780480.0 -257221.25 -1.47323275994151 -1.374 -0.8486 1720569 Maybridge1_002596 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N23 mock treatment 1175880.0 101000.0 0.49 1136130.0 111000.0 0.66 1111680.0 73978.75 0.423712729953387 0.9098 0.983 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 N24 mock treatment 1000390.0 -74400.0 -0.36 983720.0 -41800.0 -0.25 959570.0 -78131.25 -0.447496142232338 -0.6115 -0.9743 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O01 compound treatment 988160.0 -86600.0 -0.42 978480.0 -47000.0 -0.28 960160.0 -77541.25 -0.444116921703842 -0.662 -0.9822 1953671 Maybridge1_002597 CC1(C)CN=C(Nc2ccccc2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O02 compound treatment 972160.0 -103000.0 -0.5 932540.0 -92900.0 -0.55 922110.0 -115591.25 -0.66204800832975 -0.9907 -0.9932 1008471 Maybridge1_002598 C(N(Cc1ccccc1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O03 compound treatment 1134520.0 59800.0 0.29 943110.0 -82400.0 -0.49 1008450.0 -29251.25 -0.167536312685048 -0.2109 -0.3549 1953672 Maybridge1_002599 CCOC(=O)C(O)(c1ccc(N)c(C)c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O04 compound treatment 877920.0 -197000.0 -0.96 978720.0 -46800.0 -0.28 977920.0 -59781.25 -0.342396656303681 -0.9135 -0.8633 1953673 Maybridge1_002600 Fc1ccc(cc1)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O05 compound treatment 1011520.0 -63200.0 -0.31 992280.0 -33200.0 -0.2 914370.0 -123331.25 -0.706378799669685 -0.7002 -0.8798 1953674 Maybridge1_002601 CCCCCCCCCCOC(=O)c1cc(cc2/C(=N/O)/c3cc(ccc3-c21)[N+](=O)[O-])[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O06 compound treatment 709600.0 -365000.0 -1.78 747090.0 -278000.0 -1.66 733170.0 -304531.25 -1.74420042638754 -2.9928 -0.9995 1953675 Maybridge1_002602 Cc1ccc(OC(=O)c2ccc(cc2)C(C)(C)C)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O07 compound treatment 1067040.0 -7720.0 -0.04 984930.0 -40500.0 -0.24 1091390.0 53688.75 0.30750190872764 0.0166 0.0422 1953676 Maybridge1_002603 CCOc1cc([N+](=O)[O-])c(OCC)cc1N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O08 compound treatment 938900.0 -136000.0 -0.66 1048980.0 23500.0 0.14 998830.0 -38871.25 -0.222634789776802 -0.4311 -0.6038 1953677 Maybridge1_002604 Cc1ccc(OS(=O)(=O)c2cccc(c2)C(F)(F)F)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O09 compound treatment 1057600.0 -17200.0 -0.08 1151750.0 126000.0 0.75 1136800.0 99098.75 0.567587339573435 0.7128 0.7543 1549404 Maybridge1_002605 COc1ccccc1C2CCN(CC2)C(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O10 compound treatment 750120.0 -325000.0 -1.59 765120.0 -260000.0 -1.55 871840.0 -165861.25 -0.94996905234248 -2.3581 -0.9779 1128908 Maybridge1_002606 COc1ccccc1C2CCN(Cc3ccc4ccccc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O11 compound treatment 1011060.0 -63700.0 -0.31 1008710.0 -16800.0 -0.1 1074020.0 36318.75 0.20801536537174 -0.1171 -0.3024 1004233 Maybridge1_002607 N=C(Nc1ccccc1)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O12 compound treatment 1091840.0 17100.0 0.08 1042820.0 17300.0 0.1 1018190.0 -19511.25 -0.111750536502753 0.0432 0.2491 1953678 Maybridge1_002608 C[C@@]1(C[C@]1(C)C(=O)NN)C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O13 compound treatment 1044500.0 -30300.0 -0.15 1128240.0 103000.0 0.61 1152800.0 115098.75 0.659227218312318 0.6481 0.7114 1953679 Maybridge1_002609 CSCC[C@H](NC(=O)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O14 compound treatment 793390.0 -281000.0 -1.37 829680.0 -196000.0 -1.16 703590.0 -334111.25 -1.91361965220605 -2.5707 -0.9781 1953680 Maybridge1_002610 Nc1nc(cc(n1)C(F)(F)F)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O15 compound treatment 994260.0 -80500.0 -0.39 1030130.0 4660.0 0.03 987960.0 -49741.25 -0.284892632395031 -0.3756 -0.7721 1953681 Maybridge1_002611 OC(=O)c1cccc2Cc3cc(I)ccc3-c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O16 compound treatment 1125010.0 50200.0 0.25 1022370.0 -3100.0 -0.02 968680.0 -69021.25 -0.395318686275386 -0.0971 -0.2086 1408788 Maybridge1_002612 On1c(nc2C(=O)CCCc21)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O17 compound treatment 910790.0 -164000.0 -0.8 954520.0 -71000.0 -0.42 977520.0 -60181.25 -0.344687653272153 -0.9051 -0.9343 1953682 Maybridge1_002613 Clc1ccc(C(=O)O/N=C/2\CCCc3[nH]c4ccccc4c23)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O18 compound treatment 1055360.0 -19400.0 -0.09 1053950.0 28500.0 0.17 966560.0 -71141.25 -0.407460970208288 -0.1922 -0.4259 1004141 Maybridge1_002614 CCOC(=O)C(CCC#N)(CCC#N)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O19 compound treatment 848330.0 -226000.0 -1.11 973820.0 -51700.0 -0.31 995420.0 -42281.25 -0.242165538933027 -0.9559 -0.8146 1200376 Maybridge1_002615 CC1CC(C)(C)N(CCO)c2cc(C)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O20 compound treatment 993810.0 -81000.0 -0.4 975270.0 -50200.0 -0.3 1026170.0 -11531.25 -0.0660451469817346 -0.4388 -0.8778 1953683 Maybridge1_002616 COC1(CCC2CC1)CC2(O)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O21 compound treatment 1140030.0 65300.0 0.32 1039070.0 13600.0 0.08 1094400.0 56698.75 0.324741660915393 0.4183 0.9049 1066497 Maybridge1_002617 CC(C)(C)c1cc(c(Br)c(c1)C(C)(C)C)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O22 compound treatment 1056860.0 -17900.0 -0.09 1080650.0 55200.0 0.33 976410.0 -61291.25 -0.351045169859663 -0.0637 -0.1305 1194846 Maybridge1_002618 N#CC1CC2CC1N(Cc3ccccc3)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O23 mock treatment 1147840.0 73100.0 0.36 1153550.0 128000.0 0.76 1167040.0 129338.75 0.740786710389925 1.0736 0.9578 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 O24 mock treatment 1058780.0 -16000.0 -0.08 889920.0 -136000.0 -0.81 976750.0 -60951.25 -0.349097822436462 -0.712 -0.8074 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P01 compound treatment 1001480.0 -73300.0 -0.36 917180.0 -108000.0 -0.64 966280.0 -71421.25 -0.409064668086219 -0.8147 -0.9667 1953684 Maybridge1_002619 COC(=O)C1CCCC(C(=O)OC)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P02 compound treatment 982200.0 -92600.0 -0.45 979000.0 -46500.0 -0.28 958880.0 -78821.25 -0.451448112002952 -0.6813 -0.9786 1276535 Maybridge1_002620 COc1cccc(NC(=S)Nc2cccc(O)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P03 compound treatment 849610.0 -225000.0 -1.1 871080.0 -154000.0 -0.92 1080800.0 43098.75 0.246847763987342 -1.0227 -0.7034 1953685 Maybridge1_002621 C=C1CC2CC(C1)CC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P04 compound treatment 1050420.0 -24300.0 -0.12 963570.0 -61900.0 -0.37 964800.0 -72901.25 -0.417541356869565 -0.5223 -0.9175 1953686 Maybridge1_002622 O=C1NC(=O)C(=Cc2c[nH]c3ccccc23)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P05 compound treatment 927650.0 -147000.0 -0.72 938580.0 -86900.0 -0.52 885510.0 -152191.25 -0.871674230944946 -1.2166 -0.9792 1953687 Maybridge1_002623 O/N=C(\C(=O)c1ccccc1)/c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P06 compound treatment 914880.0 -160000.0 -0.78 833440.0 -192000.0 -1.14 876640.0 -161061.25 -0.922477088720815 -1.6429 -0.988 1953688 Maybridge1_002624 CCCCN1C(=O)c2cccc3cc(cc(C1=O)c23)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P07 compound treatment 685700.0 -389000.0 -1.9 768800.0 -257000.0 -1.53 741970.0 -295731.25 -1.69379849308116 -2.9566 -0.996 1620380 Maybridge1_002625 CC(C)(O)C(C)(C)CN(Cc1ccccc1)Cc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P08 compound treatment 1193300.0 119000.0 0.58 975000.0 -50500.0 -0.3 957070.0 -80631.25 -0.461814873285289 -0.1055 -0.132 1953689 Maybridge1_002626 COc1ccc(CCN2C(C(CCC2=O)C(=O)O)c3cc(OC)c(OC)c(OC)c3)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P09 compound treatment 693920.0 -381000.0 -1.86 641180.0 -384000.0 -2.29 712000.0 -325701.25 -1.86545144094393 -3.4707 -0.9951 1303983 Maybridge1_002627 OC1(CC(=O)c2ccc(F)cc2)C(=O)Nc3ccc(Br)cc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P10 compound treatment 22240.0 -1050000.0 -5.14 23070.0 -1000000.0 -5.96 25860.0 -1011841.25 -5.79531309081253 -9.7564 -0.998 1019365 Maybridge1_002628 COC1=CC(=O)C=C(OC)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P11 compound treatment 1090880.0 16100.0 0.08 1141540.0 116000.0 0.69 1142260.0 104558.75 0.598859448193079 0.7897 0.861 1002875 Maybridge1_002629 OCC1COc2ccccc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P12 compound treatment 913380.0 -161000.0 -0.79 1006090.0 -19400.0 -0.12 981200.0 -56501.25 -0.32361048116221 -0.7086 -0.8239 1953690 Maybridge1_002630 N#CCSc1nnc(SCC#N)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P13 compound treatment 1095200.0 20400.0 0.1 1141710.0 116000.0 0.69 1234940.0 197238.75 1.12968344578806 1.1089 0.835 1027517 Maybridge1_002631 OC(=O)c1cc2ccccc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P14 compound treatment 865650.0 -209000.0 -1.02 810690.0 -215000.0 -1.28 845600.0 -192101.25 -1.10025845347425 -1.9625 -0.9956 1953691 Maybridge1_002632 S=C(NCC1CCCC1NC(=S)NC2CC3CC2C=C3)NC4CC5CC4C=C5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P15 compound treatment 867130.0 -208000.0 -1.01 1031920.0 6450.0 0.04 1087090.0 49388.75 0.282873691316565 -0.4002 -0.3798 1953692 Maybridge1_002633 CC1CCCCN1Cc2c(C)c(C)c(C)c(C)c2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P16 compound treatment 1170940.0 96200.0 0.47 1034280.0 8810.0 0.05 1153660.0 115958.75 0.664152861794533 0.685 0.8402 1953693 Maybridge1_002634 CCC(=O)c1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P17 compound treatment 652190.0 -423000.0 -2.06 619710.0 -406000.0 -2.41 683870.0 -353831.25 -2.02656580275173 -3.7551 -0.9968 1953694 Maybridge1_002635 Cc1cc(CSC(=N)Nc2ccccc2)c(C)cc1CSC(=N)Nc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P18 compound treatment 1060760.0 -14000.0 -0.07 1010620.0 -14900.0 -0.09 991400.0 -46301.25 -0.265190058466171 -0.2436 -0.8465 1086332 Maybridge1_002636 CN(C)c1ccc(cc1)C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P19 compound treatment 1118880.0 44100.0 0.22 1091280.0 65800.0 0.39 1066310.0 28608.75 0.16385639880444 0.445 0.9351 1953695 Maybridge1_002637 Cc1c(C)c(C)c(CSc2nsc(SCc3c(C)c(C)c(C)c(C)c3C)c2C#N)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P20 compound treatment 669150.0 -406000.0 -1.98 630010.0 -395000.0 -2.35 728680.0 -309021.25 -1.76991686735864 -3.5237 -0.9931 1953696 Maybridge1_002638 CN(C)c1ccc(cc1)C(=O)N/N=C/c2cc(Br)cc(Br)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P21 compound treatment 1080270.0 5510.0 0.03 983620.0 -41900.0 -0.25 1036800.0 -901.25 -0.00516190254458868 -0.1311 -0.5237 1953697 Maybridge1_002639 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P22 compound treatment 1131850.0 57100.0 0.28 998650.0 -26800.0 -0.16 1088270.0 50568.75 0.289632132373558 0.2362 0.5459 1953698 Maybridge1_002640 CC(=O)C(=NNc1ccc(Br)c(Cl)c1)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P23 mock treatment 1023360.0 -51400.0 -0.25 1071040.0 45600.0 0.27 1046420.0 8718.75 0.0499365745471652 0.0403 0.108 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1231 P24 mock treatment 966210.0 -109000.0 -0.53 879050.0 -146000.0 -0.87 1104030.0 66328.75 0.379897412931358 -0.5896 -0.5419 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A01 compound treatment 945540.0 -219000.0 -1.07 920000.0 -204000.0 -1.21 832160.0 -249782.33333333 -1.43062642111136 -2.1442 -0.993 1953699 Maybridge1_002641 COc1cc(/C=N/NC(=O)CSCc2c(Cl)cccc2Cl)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A02 compound treatment 935770.0 -229000.0 -1.12 903970.0 -220000.0 -1.31 884010.0 -197932.33333333 -1.13365593907317 -2.0553 -0.9975 1953700 Maybridge1_002642 CS/C(=N\S(=O)(=O)c1ccccc1)/N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A03 compound treatment 1029440.0 -136000.0 -0.66 872770.0 -251000.0 -1.49 930660.0 -151282.33333333 -0.866468417625109 -1.744 -0.9437 1553954 Maybridge1_002643 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)N2CCC3N(C2)C(=O)c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A04 compound treatment 433450.0 -732000.0 -3.57 211850.0 -912000.0 -5.42 393390.0 -688552.33333333 -3.94367827075261 -7.4709 -0.9833 1953701 Maybridge1_002644 FC(F)(F)c1cc(NNc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A05 compound treatment 1002620.0 -162000.0 -0.79 1013820.0 -110000.0 -0.65 922830.0 -159112.33333333 -0.91131468328295 -1.3613 -0.9911 1953702 Maybridge1_002645 S=C(N/N=C/c1ccc2OCOc2c1)NC3CC4CCC3C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A06 compound treatment 1036070.0 -129000.0 -0.63 976770.0 -147000.0 -0.87 885700.0 -196242.33333333 -1.12397647688137 -1.5169 -0.9745 1953703 Maybridge1_002646 FC(F)(F)c1cc(cc(c1)C(F)(F)F)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A07 compound treatment 944610.0 -220000.0 -1.08 937500.0 -186000.0 -1.11 933090.0 -148852.33333333 -0.852550611041641 -1.753 -0.9938 1953704 Maybridge1_002647 Cc1c(C)c(C)c(COc2ccc(Cl)cc2Cl)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A08 compound treatment 907460.0 -258000.0 -1.26 804680.0 -319000.0 -1.9 752730.0 -329212.33333333 -1.88556114412571 -2.9102 -0.9846 1602202 Maybridge1_002648 Cc1ccc-2c(NC(c3cccn32)c4cc(Cl)cc(Cl)c4O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A09 compound treatment 941820.0 -223000.0 -1.09 909670.0 -214000.0 -1.27 930880.0 -151062.33333333 -0.865208369292449 -1.8637 -0.9882 1953705 Maybridge1_002649 O=C(CC(=O)N1CCCC1)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A10 compound treatment 1066660.0 -98400.0 -0.48 987910.0 -136000.0 -0.81 866480.0 -215462.33333333 -1.23405888121646 -1.4559 -0.9388 1700909 Maybridge1_002650 Clc1cc(Cl)c2OC3(CCCCC3=Cc2c1)N4CCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A11 compound treatment 125120.0 -1040000.0 -5.08 92480.0 -1030000.0 -6.13 85880.0 -996062.33333333 -5.70493946518975 -9.7673 -0.9971 1953706 Maybridge1_002651 COc1ccc(cc1CSc2ccc(Cl)cc2)C(=O)C[n+]3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A12 compound treatment 993990.0 -171000.0 -0.84 998560.0 -125000.0 -0.74 870750.0 -211192.33333333 -1.20960248857802 -1.6102 -0.9773 1953707 Maybridge1_002652 Cc1c(cc2c(c1[N+](=O)[O-])C(C)(C)CC2(C)C)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A13 compound treatment 972610.0 -192000.0 -0.94 912330.0 -211000.0 -1.26 866970.0 -214972.33333333 -1.23125240993008 -1.9791 -0.9922 1022227 Maybridge1_002653 CC(=O)Oc1ccccc1C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A14 compound treatment 976000.0 -189000.0 -0.92 912110.0 -212000.0 -1.26 812410.0 -269532.33333333 -1.54374439642967 -2.1507 -0.9798 1953708 Maybridge1_002654 C(c1cccnc1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A15 compound treatment 419530.0 -745000.0 -3.64 386960.0 -737000.0 -4.38 367040.0 -714902.33333333 -4.09459769605071 -6.9961 -0.9972 1953709 Maybridge1_002655 C/C(=N\NC(=S)N)/c1ccccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A16 compound treatment 1030100.0 -135000.0 -0.66 975770.0 -148000.0 -0.88 828320.0 -253622.33333333 -1.45261999200869 -1.7269 -0.9481 1953710 Maybridge1_002656 CCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)OCC)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A17 compound treatment 891690.0 -273000.0 -1.34 927930.0 -196000.0 -1.16 782670.0 -299272.33333333 -1.71408002103557 -2.4325 -0.9869 1953711 Maybridge1_002657 FC(F)(F)c1cc(NC(=O)c2ccc(Cl)cc2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A18 compound treatment 990420.0 -175000.0 -0.85 982050.0 -142000.0 -0.84 864060.0 -217882.33333333 -1.24791941287571 -1.6991 -0.982 1953712 Maybridge1_002658 Fc1cccc(F)c1NC(=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A19 compound treatment 438280.0 -727000.0 -3.55 484540.0 -639000.0 -3.8 428960.0 -652982.33333333 -3.73995136533123 -6.4034 -0.9996 1953713 Maybridge1_002659 COCCCNC(=S)N/N=C/c1cccc(OC)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A20 compound treatment 974800.0 -190000.0 -0.93 964880.0 -159000.0 -0.94 938360.0 -143582.33333333 -0.822366725982021 -1.5564 -0.9982 1953714 Maybridge1_002660 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A21 compound treatment 867550.0 -297000.0 -1.45 911300.0 -212000.0 -1.26 804880.0 -277062.33333333 -1.58687241436116 -2.4843 -0.9957 1953715 Maybridge1_002661 OC1=NN=CC1CCCNC(=S)Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A22 compound treatment 1004390.0 -161000.0 -0.78 952800.0 -171000.0 -1.02 875960.0 -205982.33333333 -1.17976225306367 -1.7207 -0.987 1953716 Maybridge1_002662 COc1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A23 mock treatment 1026720.0 -138000.0 -0.68 1017550.0 -106000.0 -0.63 874840.0 -207102.33333333 -1.18617704457539 -1.4392 -0.957 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 A24 mock treatment 978130.0 -187000.0 -0.91 1021440.0 -102000.0 -0.61 853600.0 -228342.33333333 -1.30782898360126 -1.6331 -0.9568 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B01 compound treatment 1051390.0 -114000.0 -0.56 1001230.0 -122000.0 -0.73 1083450.0 1507.66666667 0.00863514940701851 -0.7358 -0.8037 1953717 Maybridge1_002663 Cc1c(nnn1c2cccc(c2)C(F)(F)F)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B02 compound treatment 1069880.0 -95100.0 -0.46 1011860.0 -112000.0 -0.66 916380.0 -165562.33333333 -0.948257009399563 -1.1996 -0.9614 1953718 Maybridge1_002664 CN(C)C(=S)SCc1ccccc1C(=O)Oc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B03 compound treatment 1009450.0 -156000.0 -0.76 1032680.0 -90900.0 -0.54 1063330.0 -18612.33333333 -0.106601998107128 -0.8126 -0.8655 1953719 Maybridge1_002665 CC(=O)C(=NNc1c(F)cccc1F)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B04 compound treatment 991200.0 -174000.0 -0.85 850100.0 -274000.0 -1.63 855570.0 -226372.33333333 -1.29654582353153 -2.178 -0.9694 1953720 Maybridge1_002666 [O-][N+](=O)c1ccc(NCCc2ccccn2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B05 compound treatment 1011840.0 -153000.0 -0.75 930880.0 -193000.0 -1.15 878080.0 -203862.33333333 -1.16761996913077 -1.768 -0.9826 1953721 Maybridge1_002667 FC(F)(F)c1ccccc1NCN2C(=O)CCC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B06 compound treatment 830880.0 -334000.0 -1.63 860440.0 -263000.0 -1.57 799240.0 -282702.33333333 -1.61917547161662 -2.781 -0.9998 1130340 Maybridge1_002668 COc1ccc(Oc2cccc(F)c2C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B07 compound treatment 1029760.0 -135000.0 -0.66 933860.0 -190000.0 -1.13 960480.0 -121462.33333333 -0.695674593625515 -1.4347 -0.9686 1953722 Maybridge1_002669 COCCCNC1=NC(=O)C(CC(=O)Nc2cc(Cl)ccc2Cl)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B08 compound treatment 911620.0 -253000.0 -1.24 919300.0 -204000.0 -1.22 882050.0 -199892.33333333 -1.14488182421868 -2.0773 -0.9995 1953723 Maybridge1_002670 CN(/N=C/c1cc(Cl)cc(Cl)c1O)c2ccc(cn2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B09 compound treatment 1049760.0 -115000.0 -0.56 1028160.0 -95500.0 -0.57 995200.0 -86742.33333333 -0.496816056762137 -0.9397 -0.9982 1953724 Maybridge1_002671 CN(C)c1c(F)cc(cc1F)/C(=N/O)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B10 compound treatment 922120.0 -243000.0 -1.19 904430.0 -219000.0 -1.3 811680.0 -270262.33333333 -1.54792546589713 -2.3314 -0.9938 1953725 Maybridge1_002672 Cc1nn(c(C)c1/C=N/O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B11 compound treatment 972040.0 -193000.0 -0.94 983540.0 -140000.0 -0.83 923940.0 -158002.33333333 -0.90495716669544 -1.5478 -0.9987 1953726 Maybridge1_002673 Cc1onc(c1C(=O)OCC#C)c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B12 compound treatment 1118400.0 -46600.0 -0.23 997000.0 -127000.0 -0.75 933080.0 -148862.33333333 -0.852607885965853 -1.0585 -0.9124 1953727 Maybridge1_002674 Cc1nn(C(=O)c2ccc(Cl)cc2)c(C)c1Cc3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B13 compound treatment 1092510.0 -72500.0 -0.35 959800.0 -164000.0 -0.97 957560.0 -124382.33333333 -0.712398871495361 -1.1783 -0.9368 1953728 Maybridge1_002675 Cc1nnsc1C(=O)NCc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B14 compound treatment 1091840.0 -73200.0 -0.36 1009380.0 -114000.0 -0.68 934200.0 -147742.33333333 -0.846193094454131 -1.0872 -0.9516 1953729 Maybridge1_002676 CC(=O)C(Cc1ccc(cc1)[N+](=O)[O-])(Cc2c(F)cccc2Cl)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B15 compound treatment 1022670.0 -142000.0 -0.7 1065550.0 -58100.0 -0.35 1020080.0 -61862.33333333 -0.354316045323173 -0.8055 -0.9437 1531342 Maybridge1_002677 OC(=O)c1ccccc1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B16 compound treatment 1079040.0 -86000.0 -0.42 1141480.0 17900.0 0.11 941860.0 -140082.33333333 -0.802320502507891 -0.6445 -0.7068 1953730 Maybridge1_002678 Cc1onc(c1C(=O)NCCSCc2c(F)cccc2Cl)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B17 compound treatment 954940.0 -210000.0 -1.03 971690.0 -152000.0 -0.9 842560.0 -239382.33333333 -1.37106049993109 -1.9058 -0.9842 1953731 Maybridge1_002679 Fc1cccc(N2CCCC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B18 compound treatment 1009060.0 -156000.0 -0.76 966490.0 -157000.0 -0.93 901800.0 -180142.33333333 -1.03176384890037 -1.5751 -0.9926 1953732 Maybridge1_002680 O=C(N1CCSCC1)c2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B19 compound treatment 839610.0 -325000.0 -1.59 757360.0 -366000.0 -2.18 826370.0 -255572.33333333 -1.46378860223 -3.0205 -0.9844 1953733 Maybridge1_002681 ON(Cc1cccc(c1)C(F)(F)F)Cc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B20 compound treatment 986930.0 -178000.0 -0.87 1009160.0 -114000.0 -0.68 972410.0 -109532.33333333 -0.627345609040834 -1.2576 -0.9899 1953734 Maybridge1_002682 OCCOc1ccc(cn1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B21 compound treatment 842570.0 -322000.0 -1.58 777250.0 -346000.0 -2.06 753450.0 -328492.33333333 -1.88143734958246 -3.185 -0.9941 1953735 Maybridge1_002683 CS/C(=N\c1cccc(c1)C(F)(F)F)/N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B22 compound treatment 978310.0 -187000.0 -0.91 1024000.0 -99600.0 -0.59 941680.0 -140262.33333333 -0.803351451143703 -1.3325 -0.9854 1953736 Maybridge1_002684 Cc1c(nnn1c2ccc(F)c(Cl)c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B23 mock treatment 1057470.0 -108000.0 -0.53 1043900.0 -79700.0 -0.47 919270.0 -162672.33333333 -0.931704556302352 -1.115 -0.953 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 B24 mock treatment 1069120.0 -95900.0 -0.47 1020660.0 -103000.0 -0.61 1000900.0 -81042.33333333 -0.46416934996141 -0.892 -0.9912 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C01 compound treatment 1083550.0 -81500.0 -0.4 899160.0 -224000.0 -1.33 930350.0 -151592.33333333 -0.868243940275675 -1.5018 -0.915 1953737 Maybridge1_002685 COc1cccc(NC(=S)NNC(=O)CSCc2c(Cl)cccc2Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C02 compound treatment 995450.0 -170000.0 -0.83 983750.0 -140000.0 -0.83 876360.0 -205582.33333333 -1.1774712560952 -1.6384 -0.9853 1953738 Maybridge1_002686 FC(F)(F)c1cccc(Cc2cccc(c2)C(F)(F)F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C03 compound treatment 942130.0 -223000.0 -1.09 909220.0 -214000.0 -1.27 886830.0 -195112.33333333 -1.11750441044544 -2.01 -0.9975 1671582 Maybridge1_002687 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C04 compound treatment 283710.0 -881000.0 -4.31 239450.0 -884000.0 -5.26 253030.0 -828912.33333333 -4.74758910698947 -8.2627 -0.9967 1953739 Maybridge1_002688 Oc1c(Br)cc(Br)cc1/C=N/NC(=S)N[C@H]2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C05 compound treatment 872010.0 -293000.0 -1.43 828420.0 -295000.0 -1.76 840100.0 -241842.33333333 -1.38515013128719 -2.6398 -0.9942 1953740 Maybridge1_002689 S=C(NC1CC2CC1C=C2)N3CCC(CCCC4CCN(CC4)C(=S)NC5CC6CC5C=C6)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C06 compound treatment 1005240.0 -160000.0 -0.78 885790.0 -238000.0 -1.41 814690.0 -267252.33333333 -1.53068571370938 -2.151 -0.9665 1210996 Maybridge1_002690 COc1cccc2CC3=C(CC(C)(C)CC3=O)Oc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C07 compound treatment 1084480.0 -80500.0 -0.39 1065030.0 -58600.0 -0.35 1040960.0 -40982.33333333 -0.23472600356893 -0.5639 -0.9796 1953741 Maybridge1_002691 Cc1c(C)c(C)c(COc2ccc(I)cc2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C08 compound treatment 940390.0 -225000.0 -1.1 845480.0 -278000.0 -1.65 841560.0 -240382.33333333 -1.37678799235227 -2.3835 -0.9866 1953742 Maybridge1_002692 Clc1ccc(NC(=O)CSc2ccccn2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C09 compound treatment 996210.0 -169000.0 -0.82 896000.0 -228000.0 -1.35 930170.0 -151772.33333333 -0.869274888911488 -1.7596 -0.9733 1624927 Maybridge1_002693 Cc1onc(c1NC(=O)Nc2c(Cl)cccc2Cl)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C10 compound treatment 274880.0 -890000.0 -4.35 262600.0 -861000.0 -5.12 358490.0 -723452.33333333 -4.1435677562518 -7.8594 -0.9957 1953743 Maybridge1_002694 N/C(=N\OC(=O)c1sc2ccccc2c1Cl)/c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C11 compound treatment 1175100.0 10100.0 0.05 1257870.0 134000.0 0.8 914370.0 -167572.33333333 -0.959769269166135 -0.0648 -0.0519 1953744 Maybridge1_002695 COc1cc(ccc1CN2CCOCC2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C12 compound treatment 901610.0 -263000.0 -1.29 949170.0 -174000.0 -1.04 959840.0 -122102.33333333 -0.69934018877507 -1.7458 -0.9726 1385956 Maybridge1_002696 Cc1c(N)c2c(cc1NC(=S)Nc3ccc(Cl)c(Cl)c3)C(C)(C)CC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C13 compound treatment 1269230.0 104000.0 0.51 1292830.0 169000.0 1.01 1103610.0 21667.66666667 0.124101396618012 0.9465 0.8343 1953745 Maybridge1_002697 C/C(=N\OC(=O)c1c(C)onc1c2c(Cl)cccc2Cl)/c3ccccc3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C14 compound treatment 1037020.0 -128000.0 -0.63 1085440.0 -38200.0 -0.23 944070.0 -137872.33333333 -0.789662744257082 -0.9481 -0.9182 1020520 Maybridge1_002698 OC(=O)CSCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C15 compound treatment 1037600.0 -127000.0 -0.62 998080.0 -126000.0 -0.75 886620.0 -195322.33333333 -1.11870718385389 -1.4364 -0.9692 1953746 Maybridge1_002699 COCCCNC1=C(C#N)C(=O)NC(S1)C2CCC=CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C16 compound treatment 814970.0 -350000.0 -1.71 824700.0 -299000.0 -1.78 810500.0 -271442.33333333 -1.55468390695413 -2.9113 -0.9985 1953747 Maybridge1_002700 [O-][N+](=O)c1c(cc(cc1C(F)(F)F)C(F)(F)F)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C17 compound treatment 785060.0 -380000.0 -1.86 725400.0 -398000.0 -2.37 712370.0 -369572.33333333 -2.11672273824454 -3.6611 -0.9952 1953748 Maybridge1_002701 Fc1ccc(cc1)C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C18 compound treatment 288480.0 -877000.0 -4.28 256450.0 -867000.0 -5.16 307520.0 -774422.33333333 -4.43549804495936 -8.0107 -0.9966 1953749 Maybridge1_002702 Fc1cccc(F)c1NC(=S)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C19 compound treatment 774450.0 -391000.0 -1.91 841370.0 -282000.0 -1.68 676510.0 -405432.33333333 -2.32211061646807 -3.4115 -0.991 1953750 Maybridge1_002703 Oc1c(Cl)cc(Cl)cc1/C=N/CCCC2C=NNC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C20 compound treatment 1069950.0 -95100.0 -0.46 1010750.0 -113000.0 -0.67 929160.0 -152782.33333333 -0.87505965625688 -1.1609 -0.9701 1953751 Maybridge1_002704 [O-][N+](=O)c1cc(c(Sc2ccccn2)cc1Sc3ccccn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C21 compound treatment 1024880.0 -140000.0 -0.68 1053920.0 -69700.0 -0.41 973810.0 -108132.33333333 -0.619327119651182 -0.9922 -0.9804 1953752 Maybridge1_002705 Cc1c(C)c(C)c(CSC(=N)CC#N)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C22 compound treatment 907310.0 -258000.0 -1.26 801120.0 -323000.0 -1.92 769920.0 -312022.33333333 -1.78710554940562 -2.866 -0.9855 1337004 Maybridge1_002706 CC(C)c1ccc(NCN2C(=O)CCC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C23 mock treatment 1126460.0 -38600.0 -0.19 983630.0 -140000.0 -0.83 957460.0 -124482.33333333 -0.712971620737479 -1.0011 -0.9001 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 C24 mock treatment 961290.0 -204000.0 -1.0 944710.0 -179000.0 -1.06 963370.0 -118572.33333333 -0.679122140528304 -1.5811 -0.9836 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D01 compound treatment 981550.0 -183000.0 -0.9 925200.0 -198000.0 -1.18 890080.0 -191862.33333333 -1.0988900600766 -1.8332 -0.9937 1953753 Maybridge1_002707 Cc1c(nnn1c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D02 compound treatment 1136090.0 -28900.0 -0.14 970970.0 -153000.0 -0.91 973390.0 -108552.33333333 -0.621732666468078 -0.9647 -0.8696 1953754 Maybridge1_002708 O=C(NCc1cccs1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D03 compound treatment 1130500.0 -34500.0 -0.17 1126670.0 3050.0 0.02 1053920.0 -28022.33333333 -0.160497701790434 -0.1796 -0.769 1953755 Maybridge1_002709 Fc1cccc(F)c1NN=C2C(=O)NC(=O)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D04 compound treatment 457010.0 -708000.0 -3.46 437330.0 -686000.0 -4.08 477970.0 -603972.33333333 -3.45924696176919 -6.3506 -0.9968 1953756 Maybridge1_002710 COc1cc(NS(=O)(=O)c2c(C)c(C)c(C)c(C)c2C)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D05 compound treatment 1028050.0 -137000.0 -0.67 996800.0 -127000.0 -0.75 908030.0 -173912.33333333 -0.996081571116418 -1.3969 -0.9856 1722458 Maybridge1_002711 O=C1CCC(=O)N1CNc2ccccc2n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D06 compound treatment 858570.0 -306000.0 -1.5 843700.0 -280000.0 -1.66 842840.0 -239102.33333333 -1.36945680205316 -2.6162 -0.9968 1953757 Maybridge1_002712 Clc1cccc(Oc2ccccc2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D07 compound treatment 1183040.0 18000.0 0.09 1000160.0 -123000.0 -0.73 991520.0 -90422.33333333 -0.51789322887208 -0.6721 -0.7445 1953758 Maybridge1_002713 COCCCNC1=NC(=O)C(CC(=O)Nc2ccccc2Cl)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D08 compound treatment 1045670.0 -119000.0 -0.58 996560.0 -127000.0 -0.76 987050.0 -94892.33333333 -0.543495119994756 -1.0867 -0.9894 1313488 Maybridge1_002714 CC1CC(C)CN(C1)c2ccc(N)cc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D09 compound treatment 1065770.0 -99300.0 -0.48 953700.0 -170000.0 -1.01 912290.0 -169652.33333333 -0.97168245340219 -1.4244 -0.9602 1953759 Maybridge1_002715 C(Oc1ccccc1)C#CC#CCOc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D10 compound treatment 1106800.0 -58200.0 -0.28 938790.0 -185000.0 -1.1 926840.0 -155102.33333333 -0.888347438674018 -1.3117 -0.9099 1190260 Maybridge1_002716 Clc1cccc(Cl)c1C(=O)NCCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D11 compound treatment 1004960.0 -160000.0 -0.78 885930.0 -238000.0 -1.41 925960.0 -155982.33333333 -0.893387632004656 -1.7834 -0.9661 1953760 Maybridge1_002717 FC(F)(F)c1ccc(Cl)c(N/C=N/c2cc(ccc2Cl)C(F)(F)F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D12 compound treatment 1144610.0 -20400.0 -0.1 1271960.0 148000.0 0.88 1161890.0 79947.66666667 0.457899654924396 0.7161 0.7169 1953761 Maybridge1_002718 Cc1nn(C(=O)c2c(Cl)cccc2Cl)c(C)c1Cc3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D13 compound treatment 1186890.0 21900.0 0.11 842720.0 -281000.0 -1.67 864060.0 -217882.33333333 -1.24791941287571 -1.6232 -0.7775 1953762 Maybridge1_002719 CN(C)CCCNS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D14 compound treatment 596090.0 -569000.0 -2.78 588980.0 -535000.0 -3.18 549680.0 -532262.33333333 -3.04852848024635 -5.2005 -0.9985 1953763 Maybridge1_002720 FC(F)(F)c1cc(cc(c1)S(=O)(=O)Nc2ccc(cc2)n3cccc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D15 compound treatment 1135840.0 -29200.0 -0.14 1029990.0 -93600.0 -0.56 993850.0 -88092.33333333 -0.50454817153073 -0.6951 -0.9089 1953764 Maybridge1_002721 Cc1nnsc1C(=O)Nc2c(C)cccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D16 compound treatment 1194440.0 29400.0 0.14 1011140.0 -112000.0 -0.67 1051870.0 -30072.33333333 -0.172239061253853 -0.4027 -0.5707 1497678 Maybridge1_002722 Cc1onc(c1NC(=O)N2CCSCC2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D17 compound treatment 1007280.0 -158000.0 -0.77 1029080.0 -94500.0 -0.56 982680.0 -99262.33333333 -0.568524261875313 -1.0978 -0.9885 1953765 Maybridge1_002723 Fc1cccc(c1C#N)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D18 compound treatment 988740.0 -176000.0 -0.86 1081240.0 -42400.0 -0.25 1196890.0 114947.66666667 0.658361889665704 -0.2627 -0.236 1342287 Maybridge1_002724 Fc1ccc(NC2OC(=O)c3ccccc23)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D19 compound treatment 791050.0 -374000.0 -1.83 810880.0 -313000.0 -1.86 681290.0 -400652.33333333 -2.29473320269482 -3.4535 -0.9943 1405030 Maybridge1_002725 ON(Cc1ccc(Cl)cc1)Cc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D20 compound treatment 1018770.0 -146000.0 -0.71 967290.0 -156000.0 -0.93 935690.0 -146252.33333333 -0.837659130746573 -1.4329 -0.9944 1953766 Maybridge1_002726 Clc1cc(Cl)cc(OS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D21 compound treatment 750110.0 -415000.0 -2.03 745240.0 -378000.0 -2.25 730100.0 -351842.33333333 -2.01517429761702 -3.633 -0.9987 1953767 Maybridge1_002727 CS/C(=N\c1ccc(Cl)cc1)/NCc2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D22 compound treatment 918880.0 -246000.0 -1.2 939860.0 -184000.0 -1.09 866950.0 -214992.33333333 -1.2313669597785 -2.0362 -0.9987 1953768 Maybridge1_002728 Brc1ccc(s1)c2ccn[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D23 mock treatment 1151970.0 -13100.0 -0.06 1025880.0 -97700.0 -0.58 964400.0 -117542.33333333 -0.673222823334488 -0.7611 -0.8535 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 D24 mock treatment 1134560.0 -30500.0 -0.15 1075760.0 -47900.0 -0.28 1150360.0 68417.66666667 0.391861667308188 -0.024 -0.0474 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E01 compound treatment 1048170.0 -117000.0 -0.57 891950.0 -232000.0 -1.38 946330.0 -135612.33333333 -0.776718611385215 -1.5735 -0.9358 1953769 Maybridge1_002729 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)c2cc(OC)c(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E02 compound treatment 1168980.0 3950.0 0.02 1151040.0 27400.0 0.16 1068530.0 -13412.33333333 -0.0768190375169906 0.0609 0.3362 1953770 Maybridge1_002730 [O-][N+](=O)c1cc(Cc2cc(cc(c2)C(F)(F)F)[N+](=O)[O-])cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E03 compound treatment 979750.0 -185000.0 -0.91 906930.0 -217000.0 -1.29 920100.0 -161842.33333333 -0.926950737592772 -1.8018 -0.986 1227164 Maybridge1_002731 Clc1c(sc2ccccc12)C(=O)N3CCCN4C3c5ccccc5C4=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E04 compound treatment 1013790.0 -151000.0 -0.74 1035700.0 -87900.0 -0.52 977980.0 -103962.33333333 -0.595443476254861 -1.0723 -0.9896 1953771 Maybridge1_002732 COc1ccc(NC(=S)NNC(=NS(=O)(=O)c2ccccc2)NNC(=S)Nc3ccc(OC)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E05 compound treatment 930840.0 -234000.0 -1.14 867850.0 -256000.0 -1.52 866360.0 -215582.33333333 -1.234746180307 -2.2516 -0.9925 1192501 Maybridge1_002733 Cc1c(C)c(C)c(C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)O)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E06 compound treatment 941180.0 -224000.0 -1.09 1068730.0 -54900.0 -0.33 1000270.0 -81672.33333333 -0.467777670186753 -1.09 -0.8836 1953772 Maybridge1_002734 [O-][N+](=O)c1ccccc1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E07 compound treatment 1228980.0 64000.0 0.31 1359230.0 236000.0 1.4 1170760.0 88817.66666667 0.508702512700265 1.283 0.8424 1080021 Maybridge1_002735 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E08 compound treatment 579050.0 -586000.0 -2.86 574210.0 -549000.0 -3.27 512980.0 -568962.33333333 -3.25872745210367 -5.4206 -0.9982 1953773 Maybridge1_002736 Nc1cc(Cc2cc(N)cc(c2)C(F)(F)F)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E09 compound treatment 1087440.0 -77600.0 -0.38 1082300.0 -41300.0 -0.25 1018890.0 -63052.33333333 -0.361131761304377 -0.5692 -0.9842 1953774 Maybridge1_002737 FC(F)(F)c1cccc(c1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E10 compound treatment 186240.0 -979000.0 -4.78 124640.0 -999000.0 -5.94 241320.0 -840622.33333333 -4.81465804324149 -8.9705 -0.9946 1953775 Maybridge1_002738 Nc1ccccc1Nc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E11 compound treatment 1193210.0 28200.0 0.14 1177530.0 53900.0 0.32 1073970.0 -7972.33333333 -0.0456614787457701 0.2382 0.677 1953776 Maybridge1_002739 OC(=O)c1cccc([N+](=O)[O-])c1C(=O)Nc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E12 compound treatment 838880.0 -326000.0 -1.59 800060.0 -324000.0 -1.92 841970.0 -239972.33333333 -1.37443972045958 -2.8244 -0.9905 1953777 Maybridge1_002740 Clc1ccc(cc1)/C(=N/c2ccccc2)/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E13 compound treatment 1362880.0 198000.0 0.97 1156980.0 33400.0 0.2 1384910.0 302967.66666667 1.73524501469601 1.6745 0.8388 1953778 Maybridge1_002741 COCCCNC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E14 compound treatment 910100.0 -255000.0 -1.25 1023140.0 -100000.0 -0.6 908270.0 -173672.33333333 -0.994706972935335 -1.6384 -0.9625 1953779 Maybridge1_002742 CSC1=C(C#N)C(=O)NC(S1)c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E15 compound treatment 1095870.0 -69200.0 -0.34 1026280.0 -97300.0 -0.58 974880.0 -107062.33333333 -0.613198702760519 -0.8833 -0.9723 1953780 Maybridge1_002743 N/C(=N\O)/CC(=O)N1CCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E16 compound treatment 36110.0 -1130000.0 -5.52 53240.0 -1070000.0 -6.37 35950.0 -1045992.33333333 -5.99091316177928 -10.3182 -0.9983 1953781 Maybridge1_002744 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1O/N=C/2\CSCc3ccccc23)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E17 compound treatment 588680.0 -576000.0 -2.82 614100.0 -510000.0 -3.03 869710.0 -212232.33333333 -1.21555908069604 -4.0769 -0.9456 1953782 Maybridge1_002745 Oc1c(Cl)cc(Cl)cc1/C=N/c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E18 compound treatment 1088660.0 -76400.0 -0.37 1019470.0 -104000.0 -0.62 982360.0 -99582.33333333 -0.570357059450091 -0.9023 -0.9798 1953783 Maybridge1_002746 [O-][N+](=O)c1cc(ccc1c2ccc(cc2[N+](=O)[O-])C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E19 compound treatment 930880.0 -234000.0 -1.14 896110.0 -228000.0 -1.35 664870.0 -417072.33333333 -2.3887786282506 -2.8208 -0.9484 1953784 Maybridge1_002747 COc1cccc(/C=N/CCCC2C=NNC2=O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E20 compound treatment 880280.0 -285000.0 -1.39 845120.0 -279000.0 -1.66 805280.0 -276662.33333333 -1.58458141739269 -2.6743 -0.9974 1953785 Maybridge1_002748 Clc1ccc(NCN2C(=O)CCC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E21 compound treatment 1115530.0 -49500.0 -0.24 1109280.0 -14300.0 -0.09 1012320.0 -69622.33333333 -0.398761386511531 -0.4191 -0.884 1953786 Maybridge1_002749 COc1cc(/C=C(\C#N)/C(=S)N)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E22 compound treatment 1281340.0 116000.0 0.57 1041280.0 -82300.0 -0.49 972320.0 -109622.33333333 -0.627861083358741 -0.3171 -0.3242 1953787 Maybridge1_002750 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2nncc2c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E23 mock treatment 1164390.0 -635.0 0.0 1016360.0 -107000.0 -0.64 1136770.0 54827.66666667 0.314025045304348 -0.1888 -0.2655 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 E24 mock treatment 1336960.0 172000.0 0.84 1088100.0 -35500.0 -0.21 1005140.0 -76802.33333333 -0.439884782095606 0.1091 0.1123 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F01 compound treatment 1117560.0 -47500.0 -0.23 1079110.0 -44500.0 -0.26 983200.0 -98742.33333333 -0.5655459658163 -0.6132 -0.9206 1159680 Maybridge1_002751 Cc1cccc(NCN2C(=O)CCC2=O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F02 compound treatment 1014410.0 -151000.0 -0.74 816120.0 -308000.0 -1.83 847960.0 -233982.33333333 -1.34013204085671 -2.2543 -0.9458 1689403 Maybridge1_002752 Clc1ccc(NCc2cccnc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F03 compound treatment 1082590.0 -82400.0 -0.4 854720.0 -269000.0 -1.6 942980.0 -138962.33333333 -0.795905710996169 -1.6153 -0.8822 1953788 Maybridge1_002753 Clc1cccc(NCN2C(=O)CCC2=O)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F04 compound treatment 1022400.0 -143000.0 -0.7 1058430.0 -65200.0 -0.39 1009760.0 -72182.33333333 -0.413423767109753 -0.8648 -0.9628 1953789 Maybridge1_002754 Clc1ccc(cc1Cl)S(=O)(=O)NC(=N)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F05 compound treatment 1087790.0 -77200.0 -0.38 789870.0 -334000.0 -1.98 877640.0 -204302.33333333 -1.17014006579609 -2.0393 -0.8735 1953790 Maybridge1_002755 Oc1ccccc1/C=N/c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F06 compound treatment 331310.0 -834000.0 -4.07 353680.0 -770000.0 -4.58 383600.0 -698342.33333333 -3.99975042155597 -7.3044 -0.9981 1451316 Maybridge1_002756 Oc1ccccc1C(=O)Nc2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F07 compound treatment 897760.0 -267000.0 -1.31 864870.0 -259000.0 -1.54 825350.0 -256592.33333333 -1.4696306444996 -2.4908 -0.9977 1953791 Maybridge1_002757 COc1ccc(NC(=O)C(Cl)Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F08 compound treatment 912000.0 -253000.0 -1.24 848800.0 -275000.0 -1.63 781480.0 -300462.33333333 -1.72089573701678 -2.6508 -0.9906 1953792 Maybridge1_002758 CN(/N=C/c1cc(Cl)cc(Cl)c1O)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F09 compound treatment 1045990.0 -119000.0 -0.58 995710.0 -128000.0 -0.76 930480.0 -151462.33333333 -0.867499366260922 -1.2758 -0.9874 1953793 Maybridge1_002759 CC(=O)c1nnn(c1C)c2cccc(Cl)c2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F10 compound treatment 791740.0 -373000.0 -1.82 867610.0 -256000.0 -1.52 956160.0 -125782.33333333 -0.720417360885013 -2.3479 -0.9458 1953794 Maybridge1_002760 [O-][N+](=O)c1ccc(OC(=O)c2c(Cl)cccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F11 compound treatment 1077060.0 -88000.0 -0.43 1040420.0 -83200.0 -0.49 1041280.0 -40662.33333333 -0.232893205994152 -0.6683 -0.9608 1953795 Maybridge1_002761 FC(F)(F)c1ccccc1N/C=N/c2ccccc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F12 compound treatment 767890.0 -397000.0 -1.94 933600.0 -190000.0 -1.13 1034300.0 -47642.33333333 -0.27287110309399 -1.9302 -0.8533 1953796 Maybridge1_002762 Cc1nn(C(=O)C(C)(C)C)c(C)c1Cc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F13 compound treatment 1028180.0 -137000.0 -0.67 1064170.0 -59500.0 -0.35 1006850.0 -75092.33333333 -0.430090770055387 -0.8385 -0.9637 1953797 Maybridge1_002763 Fc1cccc(Cl)c1C(=O)Nc2ccccc2SCc3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F14 compound treatment 877760.0 -287000.0 -1.4 921790.0 -202000.0 -1.2 940910.0 -141032.33333333 -0.807761620308012 -1.9696 -0.9772 1953798 Maybridge1_002764 Cc1c(C)c(C)c(I)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F15 compound treatment 1039230.0 -126000.0 -0.61 1118420.0 -5200.0 -0.03 986330.0 -95612.33333333 -0.547618914538006 -0.6889 -0.8363 1953799 Maybridge1_002765 Cc1onc(c1C(=O)NCc2c(F)cccc2Cl)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F16 compound treatment 1148970.0 -16100.0 -0.08 1145460.0 21800.0 0.13 1009140.0 -72802.33333333 -0.416974812410885 -0.2111 -0.4757 1468180 Maybridge1_002766 Clc1ccc(cc1)S(=O)(=O)N2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F17 compound treatment 765640.0 -399000.0 -1.95 854360.0 -269000.0 -1.6 976020.0 -105922.33333333 -0.606669361400374 -2.4013 -0.925 1953800 Maybridge1_002767 FC(F)(F)c1cc(Br)ccc1/C=C/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F18 compound treatment 990340.0 -175000.0 -0.85 765120.0 -359000.0 -2.13 807200.0 -274742.33333333 -1.57358463194402 -2.6321 -0.9455 1158701 Maybridge1_002768 O=C(NC(=S)N1CCSCC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F19 compound treatment 775590.0 -389000.0 -1.9 758440.0 -365000.0 -2.17 848160.0 -233782.33333333 -1.33898654237248 -3.1254 -0.982 1354351 Maybridge1_002769 Fc1cccc(NC(=O)c2ccc(Cl)cc2Cl)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F20 compound treatment 1075440.0 -89600.0 -0.44 1258750.0 135000.0 0.8 983240.0 -98702.33333333 -0.565316866119453 -0.1152 -0.1071 1953801 Maybridge1_002770 FC(F)(F)c1cc(cc(c1)S(=O)(=O)Oc2cc(Cl)cc(Cl)c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F21 compound treatment 873930.0 -291000.0 -1.42 825920.0 -298000.0 -1.77 872570.0 -209372.33333333 -1.19917845237147 -2.5356 -0.9874 1953802 Maybridge1_002771 CS/C(=N\c1ccccc1F)/N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F22 compound treatment 1030440.0 -135000.0 -0.66 1010880.0 -113000.0 -0.67 1050960.0 -30982.33333333 -0.177451079357127 -0.8692 -0.9095 1293180 Maybridge1_002772 Clc1ccc(cc1Cl)S(=O)(=O)Nc2n[nH]c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F23 mock treatment 1180980.0 16000.0 0.08 1094980.0 -28600.0 -0.17 1036550.0 -45392.33333333 -0.259984245146334 -0.2034 -0.6349 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 F24 mock treatment 1167170.0 2140.0 0.01 1110280.0 -13300.0 -0.08 1163740.0 81797.66666667 0.468495515903579 0.2307 0.4854 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G01 compound treatment 1124200.0 -40800.0 -0.2 1031290.0 -92300.0 -0.55 1013890.0 -68052.33333333 -0.389769223410278 -0.6572 -0.9358 1953803 Maybridge1_002773 Clc1cccc(Cl)c1CSCC(=O)NNC(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G02 compound treatment 1097530.0 -67500.0 -0.33 1100040.0 -23600.0 -0.14 1017760.0 -64182.33333333 -0.367603827740311 -0.4836 -0.942 1953804 Maybridge1_002774 CC1N=C(S)N2C(C)N=C(S)N12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G03 compound treatment 1126350.0 -38700.0 -0.19 1081690.0 -41900.0 -0.25 979470.0 -102472.33333333 -0.586909512547302 -0.5919 -0.89 1201564 Maybridge1_002775 NC(=O)Nc1ccc(CC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G04 compound treatment 1067560.0 -97500.0 -0.48 970560.0 -153000.0 -0.91 949520.0 -132422.33333333 -0.75844791056165 -1.2383 -0.9698 1953805 Maybridge1_002776 Fc1ccc(NC(=S)NNC(=NS(=O)(=O)c2ccccc2)NNC(=S)Nc3ccc(F)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G05 compound treatment 1296100.0 131000.0 0.64 1148840.0 25200.0 0.15 1030760.0 -51182.33333333 -0.293146426264968 0.2871 0.3986 1171659 Maybridge1_002777 Cc1cc(C(=O)c2ccccc2C(=O)O)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G06 compound treatment 620200.0 -545000.0 -2.66 712060.0 -412000.0 -2.45 668730.0 -413212.33333333 -2.36667050750485 -4.3163 -0.9988 1953806 Maybridge1_002778 FC(F)(F)c1cc(NC(=O)C(Cl)(Cl)Cl)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G07 compound treatment 407760.0 -757000.0 -3.7 468490.0 -655000.0 -3.9 294040.0 -787902.33333333 -4.51270464279687 -6.9908 -0.9963 1953807 Maybridge1_002779 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G08 compound treatment 1211520.0 46500.0 0.23 1065380.0 -58200.0 -0.35 1069550.0 -12392.33333333 -0.0709769952473867 -0.1098 -0.2613 1953808 Maybridge1_002780 OC(=O)c1c(ccc([N+](=O)[O-])c1N2CCCCC2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G09 compound treatment 1328170.0 163000.0 0.8 1175010.0 51400.0 0.31 1104330.0 22387.66666667 0.128225191161262 0.7107 0.8232 1953809 Maybridge1_002781 C/C(=N\OC(=O)Nc1c(C)onc1c2c(Cl)cccc2Cl)/c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G10 compound treatment 815090.0 -350000.0 -1.71 827410.0 -296000.0 -1.76 778240.0 -303702.33333333 -1.7394528124614 -3.0084 -0.9999 1953810 Maybridge1_002782 CCCCNC(=S)Nc1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G11 compound treatment 1147790.0 -17200.0 -0.08 1224160.0 101000.0 0.6 1036220.0 -45722.33333333 -0.261874317645324 0.1454 0.2209 1953811 Maybridge1_002783 COc1ccc(cc1CN2CCOCC2)/C(=N/O)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G12 compound treatment 1089700.0 -75300.0 -0.37 1392430.0 269000.0 1.6 1237760.0 155817.66666667 0.89244450491934 1.2257 0.6564 1953812 Maybridge1_002784 CC(=O)C(=NNc1cc2c(c([N+](=O)[O-])c1C)C(C)(C)CC2(C)C)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G13 compound treatment 1394120.0 229000.0 1.12 1234500.0 111000.0 0.66 1105600.0 23657.66666667 0.135499106536161 1.1051 0.8461 1589549 Maybridge1_002785 NNC(=O)c1ccccc1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G14 compound treatment 828000.0 -337000.0 -1.65 825120.0 -299000.0 -1.78 861550.0 -220392.33333333 -1.26229541885288 -2.7043 -0.9904 1953813 Maybridge1_002786 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(C=C(C#N)C#N)o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G15 compound treatment 1116920.0 -48100.0 -0.24 1116430.0 -7190.0 -0.04 968690.0 -113252.33333333 -0.648651880847625 -0.5349 -0.7738 1113787 Maybridge1_002787 NC(=O)Nc1cc(Cl)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G16 compound treatment 1177440.0 12400.0 0.06 1323260.0 200000.0 1.19 1010270.0 -71672.33333333 -0.410502745974951 0.4834 0.3844 1065100 Maybridge1_002788 CC(=O)Nc1c(F)cccc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G17 compound treatment 841390.0 -324000.0 -1.58 916820.0 -207000.0 -1.23 822300.0 -259642.33333333 -1.4870994963842 -2.4815 -0.9947 1953814 Maybridge1_002789 FC(F)(F)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G18 compound treatment 1118720.0 -46300.0 -0.23 953640.0 -170000.0 -1.01 801200.0 -280742.33333333 -1.6079495864711 -1.6426 -0.8588 1953815 Maybridge1_002790 CC1(C)CC(=O)C(=NNc2ccc(cc2[N+](=O)[O-])C(F)(F)F)C(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G19 compound treatment 359260.0 -806000.0 -3.94 350450.0 -773000.0 -4.6 338880.0 -743062.33333333 -4.25588388263115 -7.3846 -0.998 1953816 Maybridge1_002791 Cc1c(C)c(C)c(CSc2nnc(/C(=C/c3c(Cl)cccc3Cl)/C#N)n2C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G20 compound treatment 1138280.0 -26700.0 -0.13 1128960.0 5340.0 0.03 1014640.0 -67302.33333333 -0.385473604094393 -0.2797 -0.6851 1231343 Maybridge1_002792 Cc1c2NC(Nc2c(C)c(C)c1C)c3cc(Cl)cc(Cl)c3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G21 compound treatment 968960.0 -196000.0 -0.96 933840.0 -190000.0 -1.13 915160.0 -166782.33333333 -0.955244550153403 -1.7562 -0.9968 1953817 Maybridge1_002793 N/C(=N\O)/Cc1nc(cs1)c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G22 compound treatment 1002900.0 -162000.0 -0.79 991260.0 -132000.0 -0.79 945440.0 -136502.33333333 -0.781816079640065 -1.3631 -1.0 1953818 Maybridge1_002794 COc1cc(OC)c(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G23 mock treatment 1045120.0 -120000.0 -0.59 1078170.0 -45500.0 -0.27 979840.0 -102102.33333333 -0.584790340351465 -0.8319 -0.9554 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 G24 mock treatment 1172900.0 7870.0 0.04 1173940.0 50300.0 0.3 1028000.0 -53942.33333333 -0.308954305347425 0.0166 0.0384 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H01 compound treatment 1143960.0 -21100.0 -0.1 1052290.0 -71300.0 -0.42 1042460.0 -39482.33333333 -0.226134764937159 -0.4349 -0.8846 1284196 Maybridge1_002795 COc1cccc(NC(=O)c2c(C)cc(C)cc2CC(C)(C)C(=O)O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H02 compound treatment 874690.0 -290000.0 -1.42 1002640.0 -121000.0 -0.72 945540.0 -136402.33333333 -0.781243330397947 -1.6854 -0.9511 1953819 Maybridge1_002796 Clc1ccc(/C=N/c2cccnc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H03 compound treatment 1112340.0 -52700.0 -0.26 1037190.0 -86400.0 -0.51 980500.0 -101442.33333333 -0.581010195353486 -0.7808 -0.9553 1953820 Maybridge1_002797 CC(=O)c1ccccc1OC(=O)c2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H04 compound treatment 984390.0 -181000.0 -0.88 972480.0 -151000.0 -0.9 938440.0 -143502.33333333 -0.821908526588327 -1.503 -0.9993 1953821 Maybridge1_002798 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)c2cccnc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H05 compound treatment 1157280.0 -7750.0 -0.04 1067150.0 -56500.0 -0.34 1021730.0 -60212.33333333 -0.344865682828225 -0.4148 -0.8592 1953822 Maybridge1_002799 Fc1cccc(F)c1C(=O)C[n+]2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H06 compound treatment 335740.0 -829000.0 -4.05 314090.0 -810000.0 -4.81 288820.0 -793122.33333333 -4.54260215323543 -7.7413 -0.9975 1608769 Maybridge1_002800 Oc1ccccc1C(=O)Nc2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H07 compound treatment 1078620.0 -86400.0 -0.42 1058720.0 -64900.0 -0.39 949440.0 -132502.33333333 -0.758906109955344 -0.9047 -0.952 1953823 Maybridge1_002801 Fc1cccc(NC2=NC(=O)C(CC(=O)Nc3cc(Cl)ccc3Cl)S2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H08 compound treatment 509650.0 -655000.0 -3.2 436760.0 -687000.0 -4.08 473020.0 -608922.33333333 -3.48759804925403 -6.2204 -0.9948 1953824 Maybridge1_002802 Fc1cccc(Cl)c1C=C(C#N)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H09 compound treatment 1437180.0 272000.0 1.33 1019870.0 -104000.0 -0.62 942570.0 -139372.33333333 -0.798253982888853 -0.0494 -0.0296 1953825 Maybridge1_002803 O=C(CC#N)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H10 compound treatment 1401380.0 236000.0 1.15 1064690.0 -58900.0 -0.35 956410.0 -125532.33333333 -0.718985487779718 0.0493 0.0351 1953826 Maybridge1_002804 [O-][N+](=O)c1cccnc1NCCCn2ccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H11 compound treatment 582000.0 -583000.0 -2.85 546850.0 -577000.0 -3.43 696320.0 -385622.33333333 -2.20864899160448 -4.9 -0.9848 1953827 Maybridge1_002805 CC1(C)OC(=O)C(=Cc2cccs2)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H12 compound treatment 1204750.0 39700.0 0.19 1443600.0 320000.0 1.9 1249450.0 167507.66666667 0.959398891322937 1.7645 0.8246 1953828 Maybridge1_002806 ON(Cc1c(F)cccc1Cl)Cc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H13 compound treatment 1137140.0 -27900.0 -0.14 967120.0 -157000.0 -0.93 857070.0 -224872.33333333 -1.28795458489976 -1.3596 -0.8525 1953829 Maybridge1_002807 [O-][N+](=O)c1ccc(OCc2c(F)cccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H14 compound treatment 842730.0 -322000.0 -1.57 757940.0 -366000.0 -2.17 760040.0 -321902.33333333 -1.84369317452688 -3.2291 -0.9915 1055619 Maybridge1_002808 Cc1cc(C)c(C)c(I)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H15 compound treatment 1081570.0 -83500.0 -0.41 1291520.0 168000.0 1.0 1051200.0 -30742.33333333 -0.176076481176044 0.2394 0.219 1420221 Maybridge1_002809 COc1ccc(OC)c(c1)S(=O)(=O)NCc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H16 compound treatment 1069140.0 -95900.0 -0.47 1245180.0 122000.0 0.72 1159140.0 77197.66666667 0.44214905076615 0.4021 0.4153 1953830 Maybridge1_002810 FC(F)(F)c1cc(cc(c1)S(=O)(=O)N2CCSCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H17 compound treatment 1136960.0 -28100.0 -0.14 1073330.0 -50300.0 -0.3 1111480.0 29537.66666667 0.1691767619727 -0.1542 -0.4167 1953831 Maybridge1_002811 COC(=O)c1ccc(CS(=O)(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H18 compound treatment 1076980.0 -88000.0 -0.43 1222740.0 99100.0 0.59 1036480.0 -45462.33333333 -0.260385169615817 -0.0584 -0.0754 1953832 Maybridge1_002812 NC(=N)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H19 compound treatment 1240820.0 75800.0 0.37 1077880.0 -45700.0 -0.27 963060.0 -118882.33333333 -0.68089766317887 -0.3364 -0.4095 1953833 Maybridge1_002813 Cc1c(C)c(sc1C#N)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H20 compound treatment 1093920.0 -71100.0 -0.35 1134450.0 10800.0 0.06 1046940.0 -35002.33333333 -0.200475598890272 -0.2792 -0.6872 1953834 Maybridge1_002814 Clc1ccc(cc1)S(=O)(=O)Oc2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H21 compound treatment 1312280.0 147000.0 0.72 1138170.0 14500.0 0.09 1109830.0 27887.66666667 0.159726399477753 0.5575 0.7514 1953835 Maybridge1_002815 CS/C(=N\C(C)c1ccccc1)/Nc2ccc(Oc3ccc(Cl)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H22 compound treatment 1168570.0 3540.0 0.02 1393070.0 269000.0 1.6 1309010.0 227067.66666667 1.30052833992843 1.6859 0.8169 1953836 Maybridge1_002816 CC(=N)NCCc1ccncc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H23 mock treatment 1302490.0 137000.0 0.67 1183150.0 59500.0 0.35 1171840.0 89897.66666667 0.514888204515139 0.8894 0.9696 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 H24 mock treatment 1164800.0 -225.0 0.0 1217690.0 94100.0 0.56 1132920.0 50977.66666667 0.291974199482805 0.4909 0.778 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I01 compound treatment 1125240.0 -39800.0 -0.19 1013600.0 -110000.0 -0.65 887650.0 -194292.33333333 -1.11280786666007 -1.1324 -0.8675 1953837 Maybridge1_002817 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NNC(=S)NCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I02 compound treatment 1265200.0 100000.0 0.49 1297810.0 174000.0 1.04 1198620.0 116677.66666667 0.668270451554346 1.2664 0.9549 1953838 Maybridge1_002818 SC1=NC2(CCCCC2)NN1c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I03 compound treatment 904800.0 -260000.0 -1.27 833440.0 -290000.0 -1.73 791250.0 -290692.33333333 -1.66493813606185 -2.6916 -0.9917 1953839 Maybridge1_002819 COc1ccc(OC)c(c1)C(=O)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I04 compound treatment 1100800.0 -64200.0 -0.31 1340320.0 217000.0 1.29 1099450.0 17507.66666667 0.100275028145902 0.6207 0.4667 1953840 Maybridge1_002820 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I05 compound treatment 1187360.0 22300.0 0.11 1225120.0 101000.0 0.6 1041150.0 -40792.33333333 -0.233637780008905 0.2766 0.4214 1953841 Maybridge1_002821 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)ON=C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I06 compound treatment 1395460.0 230000.0 1.13 1152010.0 28400.0 0.17 1008160.0 -73782.33333333 -0.422587754983641 0.5035 0.4146 1953842 Maybridge1_002822 OC(=O)/C=C/C(=O)Nc1ccccc1SCCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I07 compound treatment 1123740.0 -41300.0 -0.2 1065780.0 -57800.0 -0.34 1013280.0 -68662.33333333 -0.393262993787198 -0.5421 -0.9679 1953843 Maybridge1_002823 COc1cccc(NC(=S)N(CCC#N)CCC#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I08 compound treatment 1131930.0 -33100.0 -0.16 1200370.0 76700.0 0.46 1032260.0 -49682.33333333 -0.284555187633198 0.0058 0.0104 1953844 Maybridge1_002824 Clc1ccc(CSc2ccccc2n3cccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I09 compound treatment 1185880.0 20900.0 0.1 938330.0 -185000.0 -1.1 1045560.0 -36382.33333333 -0.208379538431501 -0.6976 -0.6196 1953845 Maybridge1_002825 Cc1c(C)c(C)c(C(=O)Cc2ccccc2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I10 compound treatment 845500.0 -320000.0 -1.56 800960.0 -323000.0 -1.92 767600.0 -314342.33333333 -1.80039333182276 -3.0486 -0.9964 1953846 Maybridge1_002826 CCCCNC(=S)Nc1ccc(cc1)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I11 compound treatment 1080210.0 -84800.0 -0.41 1175760.0 52100.0 0.31 1076190.0 -5752.33333333 -0.03294644557075 -0.0793 -0.1529 1953847 Maybridge1_002827 COc1ccc(cc1CSCC(=O)Nc2ccc(Cl)cc2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I12 compound treatment 209330.0 -956000.0 -4.67 273520.0 -850000.0 -5.06 250470.0 -831472.33333333 -4.76225148758769 -8.364 -0.9994 1953848 Maybridge1_002828 FC(F)(F)c1cccc(NC(=S)Nc2ccc(Cl)c(Cl)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I13 compound treatment 913960.0 -251000.0 -1.23 949880.0 -174000.0 -1.03 752240.0 -329702.33333333 -1.88836761541209 -2.395 -0.9667 1953849 Maybridge1_002829 O=C(N/N=C/C=C/c1ccccc1)c2ccccc2n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I14 compound treatment 710430.0 -455000.0 -2.22 629500.0 -494000.0 -2.94 564360.0 -517582.33333333 -2.96444889150343 -4.6903 -0.992 1953850 Maybridge1_002830 NC(=S)/C(=C/c1ccc(o1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I15 compound treatment 790480.0 -375000.0 -1.83 790280.0 -333000.0 -1.98 796670.0 -285272.33333333 -1.63389512713905 -3.1443 -0.9969 1953851 Maybridge1_002831 CCOc1ccc(/C=N/NC(=S)NCCCOC)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I16 compound treatment 857280.0 -308000.0 -1.5 726240.0 -397000.0 -2.36 786080.0 -295862.33333333 -1.69454927187935 -3.2108 -0.9808 1953852 Maybridge1_002832 FC(F)(F)c1cc(NCCC#N)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I17 compound treatment 952480.0 -213000.0 -1.04 863970.0 -260000.0 -1.54 845760.0 -236182.33333333 -1.35273252418331 -2.272 -0.9876 1953853 Maybridge1_002833 Clc1ccc(NC(=S)NNC(=O)CC#N)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I18 compound treatment 820130.0 -345000.0 -1.69 902660.0 -221000.0 -1.31 839040.0 -242902.33333333 -1.39122127325364 -2.5347 -0.9941 1953854 Maybridge1_002834 [O-][N+](=O)c1cc(ccc1NN=C2C(=O)NC(=O)NC2=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I19 compound treatment 1177120.0 12100.0 0.06 1102240.0 -21400.0 -0.13 1089320.0 7377.66666667 0.0422555299193465 -0.0149 -0.1018 1953855 Maybridge1_002835 Cc1c(C)c(C)c(CSc2nnc(/C(=C/c3cccs3)/C#N)n2C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I20 compound treatment 1106480.0 -58500.0 -0.29 1081020.0 -42600.0 -0.25 991200.0 -90742.33333333 -0.519726026446858 -0.6115 -0.9479 1953856 Maybridge1_002836 FC(F)(F)c1ccc(NCN2C(=O)CCC2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I21 compound treatment 884550.0 -280000.0 -1.37 832640.0 -291000.0 -1.73 906260.0 -175682.33333333 -1.00621923270191 -2.3711 -0.9775 1953857 Maybridge1_002837 COC(=O)c1c2CC(C)(C)C(=O)c2c(C)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I22 compound treatment 1226320.0 61300.0 0.3 1058470.0 -65200.0 -0.39 818180.0 -263762.33333333 -1.51069676515946 -0.923 -0.5812 1953858 Maybridge1_002838 CS(=O)(=O)c1ccc(cc1NNc2cc(ccc2S(=O)(=O)C)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I23 mock treatment 1290930.0 126000.0 0.62 1205130.0 81500.0 0.48 1150750.0 68807.66666667 0.394095389352448 0.8625 0.9838 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 I24 mock treatment 1148200.0 -16800.0 -0.08 1244170.0 121000.0 0.72 1183650.0 101707.66666667 0.582529890009278 0.7027 0.7578 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J01 compound treatment 1084710.0 -80300.0 -0.39 1177610.0 54000.0 0.32 985210.0 -96732.33333333 -0.554033706049728 -0.3611 -0.4808 1953859 Maybridge1_002839 Clc1cc(Cl)c(NCN2C(=O)CCC2=O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J02 compound treatment 733120.0 -432000.0 -2.11 1075170.0 -48500.0 -0.29 906740.0 -175202.33333333 -1.00347003633974 -1.964 -0.8342 1953860 Maybridge1_002840 CCOC(=S)SCc1c(F)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J03 compound treatment 1333410.0 168000.0 0.82 1120190.0 -3430.0 -0.02 1054980.0 -26962.33333333 -0.154426559823983 0.374 0.4467 1145147 Maybridge1_002841 Fc1cccc(F)c1C(=O)N2CCN(CC2)C(=O)c3c(F)cccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J04 compound treatment 1060670.0 -104000.0 -0.51 939710.0 -184000.0 -1.09 902240.0 -179702.33333333 -1.02924375223505 -1.52 -0.9584 1953861 Maybridge1_002842 Fc1ccc(c(F)c1)n2c(S)nc3ccccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J05 compound treatment 954100.0 -211000.0 -1.03 890400.0 -233000.0 -1.39 867950.0 -213992.33333333 -1.22563946735732 -2.1033 -0.9929 1675003 Maybridge1_002843 CCOC(=O)c1c(Cl)cc(C)cc1N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J06 compound treatment 1376800.0 212000.0 1.03 1176520.0 52900.0 0.31 1134210.0 52267.66666667 0.299362664706127 0.9518 0.8482 1953862 Maybridge1_002844 CSCCNC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J07 compound treatment 610100.0 -555000.0 -2.71 867810.0 -256000.0 -1.52 732000.0 -349942.33333333 -2.00429206201677 -3.6008 -0.9735 1953863 Maybridge1_002845 FC(F)(F)c1cc(c2cccs2)n(n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J08 compound treatment 455520.0 -710000.0 -3.47 668280.0 -455000.0 -2.71 581040.0 -500902.33333333 -2.86891431791814 -5.2211 -0.9942 1506264 Maybridge1_002846 NCC(O)COc1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J09 compound treatment 1328680.0 164000.0 0.8 1167420.0 43800.0 0.26 1083530.0 1587.66666667 0.00909334880071293 0.6173 0.734 1953864 Maybridge1_002847 COc1ccc(Br)c(c1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J10 compound treatment 1274660.0 110000.0 0.54 1153510.0 29900.0 0.18 1060650.0 -21292.33333333 -0.121951677795891 0.3415 0.5914 1953865 Maybridge1_002848 [O-][N+](=O)c1cccnc1Sc2ccccc2C3=NCCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J11 compound treatment 1505460.0 340000.0 1.66 1301530.0 178000.0 1.06 1185790.0 103847.66666667 0.594786723790603 1.9145 0.9298 1953866 Maybridge1_002849 Fc1cccc(N2CCOCC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J12 compound treatment 1240100.0 75100.0 0.37 1389300.0 266000.0 1.58 1298430.0 216487.66666667 1.23993147011234 1.8398 0.9012 1953867 Maybridge1_002850 CC(C)(C)n1cnnc1SCc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J13 compound treatment 1172970.0 7940.0 0.04 1215890.0 92300.0 0.55 1156210.0 74267.66666667 0.425367497972092 0.5848 0.841 1953868 Maybridge1_002851 Fc1cccc(Cl)c1CNC(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J14 compound treatment 1443060.0 278000.0 1.36 1241850.0 118000.0 0.7 1106590.0 24647.66666667 0.141169324033129 1.2717 0.8279 1041480 Maybridge1_002852 Cc1cc(C)c(I)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J15 compound treatment 1243810.0 78800.0 0.38 1248480.0 125000.0 0.74 1278880.0 196937.66666667 1.12795899327827 1.3021 0.9273 1953869 Maybridge1_002853 FC(F)(F)c1cccc(CSc2ccccc2NC(=O)c3ccc(Cl)c(Cl)c3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J16 compound treatment 704700.0 -460000.0 -2.25 747280.0 -376000.0 -2.24 677830.0 -404112.33333333 -2.31455032647211 -3.9269 -0.9999 1713840 Maybridge1_002854 Clc1ccc(cc1Cl)S(=O)(=O)Nc2cccc(C#C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J17 compound treatment 1086100.0 -78900.0 -0.39 1028290.0 -95300.0 -0.57 1053870.0 -28072.33333333 -0.160784076411493 -0.6428 -0.9127 1953870 Maybridge1_002855 Clc1cccc(N2CCCC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J18 compound treatment 412800.0 -752000.0 -3.68 501440.0 -622000.0 -3.7 298350.0 -783592.33333333 -4.48801915046158 -6.8492 -0.9955 1953871 Maybridge1_002856 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)c2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J19 compound treatment 1099150.0 -65900.0 -0.32 1111310.0 -12300.0 -0.07 984190.0 -97752.33333333 -0.559875748319331 -0.5513 -0.8483 1953872 Maybridge1_002857 C(/N=C/c1cccs1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J20 compound treatment 1243060.0 78000.0 0.38 1081730.0 -41900.0 -0.25 987940.0 -94002.33333333 -0.538397651739906 -0.2346 -0.3326 1953873 Maybridge1_002858 OCCOc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J21 compound treatment 1146790.0 -18200.0 -0.09 963490.0 -160000.0 -0.95 915040.0 -166902.33333333 -0.955931849243944 -1.1531 -0.8528 1953874 Maybridge1_002859 COc1ccc(/N=C(\SC)/N2CCOCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J22 compound treatment 1093070.0 -72000.0 -0.35 1398400.0 275000.0 1.63 1272250.0 190307.66666667 1.08998571852585 1.3697 0.6864 1953875 Maybridge1_002860 CC(=N)NCCCn1ccnc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J23 mock treatment 1187790.0 22800.0 0.11 1356640.0 233000.0 1.39 1242400.0 160457.66666667 0.919020069753617 1.3948 0.837 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 J24 mock treatment 1291200.0 126000.0 0.62 1324210.0 201000.0 1.19 1219610.0 137667.66666667 0.788490517474919 1.4998 0.9632 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K01 compound treatment 734120.0 -431000.0 -2.11 715680.0 -408000.0 -2.43 654100.0 -427842.33333333 -2.45046372162671 -4.0309 -0.9977 1953876 Maybridge1_002861 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)N/N=C/C=C/c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K02 compound treatment 1281720.0 117000.0 0.57 1191600.0 68000.0 0.4 1042620.0 -39322.33333333 -0.22521836614977 0.4325 0.589 1953877 Maybridge1_002862 Fc1ccc(cc1)C(=O)NNC(=NS(=O)(=O)c2ccccc2)NNC(=O)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K03 compound treatment 501140.0 -664000.0 -3.24 495240.0 -628000.0 -3.74 456410.0 -625532.33333333 -3.58273169836983 -6.0986 -0.9983 1953878 Maybridge1_002863 COc1ccc(OC)c(c1)C(=O)c2cc(OC)c(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K04 compound treatment 666560.0 -498000.0 -2.44 957690.0 -166000.0 -0.99 665530.0 -416412.33333333 -2.38499848325262 -3.3528 -0.9448 1953879 Maybridge1_002864 Clc1cc(Cl)c(Cl)c(c1Cl)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K05 compound treatment 942270.0 -223000.0 -1.09 949560.0 -174000.0 -1.04 924980.0 -156962.33333333 -0.899000574577413 -1.745 -0.9969 1953880 Maybridge1_002865 COc1ccc(cc1)/C(=N/OCc2c(Cl)cccc2Cl)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K06 compound treatment 789240.0 -376000.0 -1.84 685790.0 -438000.0 -2.6 737840.0 -344102.33333333 -1.97084350627708 -3.7011 -0.988 1953881 Maybridge1_002866 Nc1ccccc1SCc2cc(Cl)cc3COCOc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K07 compound treatment 1290190.0 125000.0 0.61 1173940.0 50300.0 0.3 1179150.0 97207.66666667 0.556756174113967 0.8473 0.9634 1677495 Maybridge1_002867 Cc1onc(c1NC(=O)Nc2cccc(Cl)c2Cl)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K08 compound treatment 1354350.0 189000.0 0.93 1288690.0 165000.0 0.98 1299860.0 217917.66666667 1.24812178427463 1.8214 0.9911 1330991 Maybridge1_002868 CCOC(=O)C(C(Nc1ccccc1)c2ccccn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K09 compound treatment 1199970.0 34900.0 0.17 1124070.0 446.0 0.0 1007100.0 -74842.33333333 -0.428658896950092 -0.1474 -0.3194 1953882 Maybridge1_002869 COc1ccc(cc1CSc2ccccn2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K10 compound treatment 971400.0 -194000.0 -0.95 927460.0 -196000.0 -1.17 721440.0 -360502.33333333 -2.06477438198444 -2.4118 -0.9446 1060483 Maybridge1_002870 Clc1ccc(cc1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K11 compound treatment 1324800.0 160000.0 0.78 1281970.0 158000.0 0.94 1255940.0 173997.66666667 0.996570317136397 1.5697 0.9949 1660885 Maybridge1_002871 Clc1ccc(cc1)C(=O)Nc2ccccc2C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K12 compound treatment 1314590.0 150000.0 0.73 1244360.0 121000.0 0.72 1250150.0 168207.66666667 0.963408136017763 1.3926 0.9903 1953883 Maybridge1_002872 Cc1c(NN=C2C(=O)CC(C)(C)CC2=O)cc3c(c1[N+](=O)[O-])C(C)(C)CC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K13 compound treatment 905120.0 -260000.0 -1.27 700640.0 -423000.0 -2.52 689760.0 -392182.33333333 -2.24622134188743 -3.4822 -0.9664 1953884 Maybridge1_002873 Clc1cccc(NC(=S)NNC(=O)c2ccccc2n3cccc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K14 compound treatment 1313280.0 148000.0 0.72 1271240.0 148000.0 0.88 1063200.0 -18742.33333333 -0.107346572121881 0.863 0.755 1233497 Maybridge1_002874 C1CN(CCO1)C(N2CCOCC2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K15 compound treatment 356370.0 -809000.0 -3.95 327680.0 -796000.0 -4.73 265630.0 -816312.33333333 -4.6754227024826 -7.7131 -0.9968 1953885 Maybridge1_002875 COCCCNC(=S)N/N=C/c1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K16 compound treatment 28840.0 -1140000.0 -5.55 28690.0 -1090000.0 -6.51 26900.0 -1055042.33333333 -6.04274696819096 -10.453 -0.9979 1953886 Maybridge1_002876 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2nc3ccccc3c(=O)n2c4ccc(F)cc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K17 compound treatment 1217020.0 52000.0 0.25 1261720.0 138000.0 0.82 1165090.0 83147.66666667 0.476227630672173 0.8957 0.9115 1953887 Maybridge1_002877 COc1ccccc1NC(=S)NNC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K18 compound treatment 697780.0 -467000.0 -2.28 891810.0 -232000.0 -1.38 929600.0 -152342.33333333 -0.87253955959156 -2.6177 -0.9329 1953888 Maybridge1_002878 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)c2ccccc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K19 compound treatment 828770.0 -336000.0 -1.64 1063630.0 -60000.0 -0.36 769500.0 -312442.33333333 -1.78951109622252 -2.1877 -0.891 1704769 Maybridge1_002879 CCc1cc2c(cc1c3csc(CC#N)n3)C(C)(C)CCC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K20 compound treatment 1391210.0 226000.0 1.11 1378470.0 255000.0 1.52 1286630.0 204687.66666667 1.17234705954242 2.1898 0.99 1953889 Maybridge1_002880 Cc1nc2cc(Cl)c(Cl)cc2nc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K21 compound treatment 1174940.0 9910.0 0.05 1067260.0 -56400.0 -0.34 998150.0 -83792.33333333 -0.479919954119655 -0.4426 -0.7536 1953890 Maybridge1_002881 N/C(=N\O)/Cc1nc(cs1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K22 compound treatment 1445690.0 281000.0 1.37 1179970.0 56300.0 0.34 941050.0 -140892.33333333 -0.806959771369047 0.5193 0.3193 1408145 Maybridge1_002882 O=C1CCC(=O)N1CNc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K23 mock treatment 1204640.0 39600.0 0.19 1168200.0 44600.0 0.27 1062530.0 -19412.33333333 -0.111183992044072 0.2006 0.5789 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 K24 mock treatment 1173280.0 8250.0 0.04 1272090.0 148000.0 0.88 1235680.0 153737.66666667 0.880531320683285 1.0414 0.8347 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L01 compound treatment 1244370.0 79300.0 0.39 1107370.0 -16300.0 -0.1 994080.0 -87862.33333333 -0.503230848273859 -0.1225 -0.1907 1149953 Maybridge1_002883 Cc1cc(C)c(C(=O)N2CCOCC2)c(CC(C)(C)C(=O)O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L02 compound treatment 977150.0 -188000.0 -0.92 951220.0 -172000.0 -1.03 892260.0 -189682.33333333 -1.08640412659843 -1.7491 -0.9976 1076994 Maybridge1_002884 O=c1cc(cc(o1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L03 compound treatment 1001760.0 -163000.0 -0.8 1129700.0 6080.0 0.04 1021540.0 -60402.33333333 -0.34595390638825 -0.6394 -0.7348 1953891 Maybridge1_002885 FC(F)(F)c1cc(cc(c1)C(F)(F)F)N2N=NC3C4CC(C5CCCC54)C32N6CCOCC6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L04 compound treatment 1068080.0 -96900.0 -0.47 1127450.0 3830.0 0.02 975960.0 -105982.33333333 -0.607013010945645 -0.6108 -0.7929 1953892 Maybridge1_002886 Cc1c(C)c(C)c(C(=O)c2cccs2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L05 compound treatment 1282040.0 117000.0 0.57 1083200.0 -40400.0 -0.24 1170030.0 88087.66666667 0.504521443232803 0.4826 0.6036 1953893 Maybridge1_002887 CC(C)(C)n1nc(cc1O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L06 compound treatment 1337390.0 172000.0 0.84 1309330.0 186000.0 1.1 1013520.0 -68422.33333333 -0.391888395606115 0.8975 0.622 1953894 Maybridge1_002888 Fc1ccccc1C(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L07 compound treatment 1173440.0 8410.0 0.04 1518410.0 395000.0 2.35 1398250.0 316307.66666667 1.81164976359456 2.4251 0.8177 1953895 Maybridge1_002889 NC1=NC2(CS1)CSC(=N2)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L08 compound treatment 1263880.0 98900.0 0.48 1437440.0 314000.0 1.87 1365500.0 283557.66666667 1.6240743868009 2.2939 0.9101 1504767 Maybridge1_002890 Fc1ccc(NC(=O)CCN2CCOCC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L09 compound treatment 841530.0 -323000.0 -1.58 828850.0 -295000.0 -1.75 865440.0 -216502.33333333 -1.24001547333448 -2.6405 -0.9904 1953896 Maybridge1_002891 FC(F)(F)c1cc(N/N=C(\C#N)/C(=O)c2ccco2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L10 compound treatment 1313700.0 149000.0 0.73 1342630.0 219000.0 1.3 1281440.0 199497.66666667 1.14262137387649 1.831 0.9746 1953897 Maybridge1_002892 Clc1cc(Cl)cc(c1)C(=O)c2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L11 compound treatment 164080.0 -1000000.0 -4.89 296070.0 -828000.0 -4.92 254760.0 -827182.33333333 -4.73768054510083 -8.4 -0.9999 1953898 Maybridge1_002893 OC(c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L12 compound treatment 1371160.0 206000.0 1.01 1284510.0 161000.0 0.96 1126040.0 44097.66666667 0.252569051625085 1.2797 0.9063 1953899 Maybridge1_002894 CC(C)(C)n1cnnc1SCc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L13 compound treatment 1459070.0 294000.0 1.44 1406850.0 283000.0 1.68 1379040.0 297097.66666667 1.70162463418368 2.7843 0.9972 1953900 Maybridge1_002895 CNc1nnc(s1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L14 compound treatment 1296980.0 132000.0 0.64 1279850.0 156000.0 0.93 1146660.0 64717.66666667 0.370669945349821 1.1226 0.9434 1511675 Maybridge1_002896 CSC1=C(C#N)C(=O)NC(C)(C)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L15 compound treatment 1008340.0 -157000.0 -0.77 920160.0 -203000.0 -1.21 805160.0 -276782.33333333 -1.58526871648323 -2.0558 -0.9624 1953901 Maybridge1_002897 Fc1cccc(Cl)c1CSc2ccccc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L16 compound treatment 1148000.0 -17000.0 -0.08 1034890.0 -88700.0 -0.53 946310.0 -135632.33333333 -0.776833161233639 -0.8012 -0.8498 1953902 Maybridge1_002898 Cc1cc(Br)c(NC(=O)C(Cl)(Cl)Cl)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L17 compound treatment 1219050.0 54000.0 0.26 1150350.0 26700.0 0.16 1035680.0 -46262.33333333 -0.264967163552761 0.0912 0.2244 1953903 Maybridge1_002899 CN(C)CCCNc1cccc(Cl)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L18 compound treatment 1366880.0 202000.0 0.99 1442810.0 319000.0 1.9 1381700.0 299757.66666667 1.71685976402402 2.6565 0.9685 1021479 Maybridge1_002900 OCCOc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L19 compound treatment 1137600.0 -27400.0 -0.13 1386560.0 263000.0 1.56 1231060.0 149117.66666667 0.854070305697433 1.3185 0.738 1953904 Maybridge1_002901 Clc1cccc(Cl)c1OCC#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L20 compound treatment 1337570.0 173000.0 0.84 1251410.0 128000.0 0.76 1197990.0 116047.66666667 0.664662131329002 1.3092 0.9954 1465575 Maybridge1_002902 Cc1onc(c1C(=O)Oc2ccc(Cl)c(Cl)c2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L21 compound treatment 1285920.0 121000.0 0.59 1281120.0 157000.0 0.94 1381670.0 299727.66666667 1.71668793925139 1.8729 0.9168 1953905 Maybridge1_002903 Fc1ccc(c(F)c1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L22 compound treatment 923250.0 -242000.0 -1.18 951370.0 -172000.0 -1.02 904210.0 -177732.33333333 -1.01796059216533 -1.8611 -0.9975 1046732 Maybridge1_002904 Ic1ccc(I)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L23 mock treatment 1332130.0 167000.0 0.82 1053500.0 -70100.0 -0.42 1022910.0 -59032.33333333 -0.338107241771233 0.0354 0.0362 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 L24 mock treatment 1088010.0 -77000.0 -0.38 1386150.0 263000.0 1.56 1213850.0 131907.66666667 0.755500161128921 1.1203 0.6312 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M01 compound treatment 1176640.0 11600.0 0.06 1244960.0 121000.0 0.72 1045620.0 -36322.33333333 -0.20803588888623 0.3292 0.4372 1361526 Maybridge1_002905 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)O)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M02 compound treatment 1129530.0 -35500.0 -0.17 1173200.0 49600.0 0.29 1025150.0 -56792.33333333 -0.325277658747789 -0.1177 -0.2494 1953906 Maybridge1_002906 CSC1=NC(C)N2N1C(C)N=C2SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M03 compound treatment 679230.0 -486000.0 -2.37 666190.0 -457000.0 -2.72 660280.0 -421662.33333333 -2.41506781846382 -4.3352 -0.9981 1953907 Maybridge1_002907 COc1cc(/C=N/NC(=S)NC2CC3CCC2C3)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M04 compound treatment 752930.0 -412000.0 -2.01 805440.0 -318000.0 -1.89 828480.0 -253462.33333333 -1.45170359322131 -3.093 -0.991 1953908 Maybridge1_002908 Clc1c(Cl)c(Cl)c(c(Cl)c1Cl)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M05 compound treatment 1402480.0 237000.0 1.16 1158510.0 34900.0 0.21 1162150.0 80207.66666667 0.459388802953903 1.0548 0.8339 1953909 Maybridge1_002909 C/C(=N\OC(=O)c1ccc(Cl)cc1)/c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M06 compound treatment 1385010.0 220000.0 1.07 1064060.0 -59600.0 -0.35 1314460.0 232517.66666667 1.33174317362386 1.1849 0.678 1196063 Maybridge1_002910 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M07 compound treatment 1201410.0 36400.0 0.18 1473690.0 350000.0 2.08 1294620.0 212677.66666667 1.21810972398765 2.0078 0.8302 1953910 Maybridge1_002911 NC(=O)NC1(CCCCC1)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M08 compound treatment 919290.0 -246000.0 -1.2 994560.0 -129000.0 -0.77 889830.0 -192112.33333333 -1.1003219331819 -1.7716 -0.984 1953911 Maybridge1_002912 FC(F)(F)c1cccc(NC(=S)NN/C(=N\S(=O)(=O)c2ccccc2)/N3CCCC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M09 compound treatment 457620.0 -707000.0 -3.46 409800.0 -714000.0 -4.24 418970.0 -662972.33333333 -3.79716901461882 -6.6385 -0.9965 1953912 Maybridge1_002913 COc1ccc(cc1CSC#N)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M10 compound treatment 106190.0 -1060000.0 -5.17 91840.0 -1030000.0 -6.14 94000.0 -987942.33333333 -5.65843222672976 -9.7961 -0.9976 1953913 Maybridge1_002914 C/C(=N\NC(=S)Nc1cccc(c1)C(F)(F)F)/c2cc(Cl)cc(Cl)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M11 compound treatment 902110.0 -263000.0 -1.28 976980.0 -147000.0 -0.87 923620.0 -158322.33333333 -0.906789964270218 -1.7686 -0.9837 1953914 Maybridge1_002915 Cc1onc(c1C(=O)ONC(=O)c2ccccc2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M12 compound treatment 1385340.0 220000.0 1.08 1276320.0 153000.0 0.91 1156450.0 74507.66666667 0.426742096153175 1.3921 0.946 1953915 Maybridge1_002916 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)NNC(=O)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M13 compound treatment 649510.0 -516000.0 -2.52 538880.0 -585000.0 -3.48 523290.0 -558652.33333333 -3.1996770052413 -5.3091 -0.9915 1953916 Maybridge1_002917 COc1cc(cc(OC)c1OC)C(=O)O/N=C(\N)/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M14 compound treatment 696230.0 -469000.0 -2.29 626500.0 -497000.0 -2.96 548920.0 -533022.33333333 -3.05288137448645 -4.7917 -0.9926 1953917 Maybridge1_002918 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(/C=N/NC(=O)CC#N)o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M15 compound treatment 1138930.0 -26100.0 -0.13 989340.0 -134000.0 -0.8 974560.0 -107382.33333333 -0.615031500335297 -0.8897 -0.8758 1953918 Maybridge1_002919 Cc1c(C)c(C)c(CO)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M16 compound treatment 79060.0 -1090000.0 -5.31 53370.0 -1070000.0 -6.36 60000.0 -1021942.33333333 -5.85316696904989 -10.1171 -0.9973 1953919 Maybridge1_002920 Cc1cc(Br)ccc1n2c(Sc3c(cc(cc3[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])nc4ccccc4c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M17 compound treatment 1151380.0 -13600.0 -0.07 1021500.0 -102000.0 -0.61 930170.0 -151772.33333333 -0.869274888911488 -0.891 -0.8386 1953920 Maybridge1_002921 Clc1ccc(cc1)c2csc(CC#N)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M18 compound treatment 1140730.0 -24300.0 -0.12 1189780.0 66200.0 0.39 1036640.0 -45302.33333333 -0.259468770828428 0.0088 0.0181 1953921 Maybridge1_002922 Nc1ccccc1SCC(=O)Nc2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M19 compound treatment 884080.0 -281000.0 -1.37 784590.0 -339000.0 -2.02 823680.0 -258262.33333333 -1.47919555684297 -2.8105 -0.9853 1953922 Maybridge1_002923 COCCCNC(=S)N/N=C/c1ccccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M20 compound treatment 1316010.0 151000.0 0.74 1218920.0 95300.0 0.57 1095530.0 13587.66666667 0.0778232578548757 0.798 0.8549 1953923 Maybridge1_002924 CS(=O)(=O)Cc1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M21 compound treatment 1044610.0 -120000.0 -0.59 947250.0 -176000.0 -1.05 837540.0 -244402.33333333 -1.39981251188541 -1.7534 -0.9501 1395529 Maybridge1_002925 NNC(=S)Nc1ccc(cc1)S(=O)(=O)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M22 compound treatment 971290.0 -194000.0 -0.95 949600.0 -174000.0 -1.03 1151250.0 69307.66666667 0.396959135563038 -0.9148 -0.6276 1060489 Maybridge1_002926 Ic1ccc(cc1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M23 mock treatment 1120590.0 -44400.0 -0.22 1092320.0 -31300.0 -0.19 1004860.0 -77082.33333333 -0.441488479973536 -0.4877 -0.9272 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 M24 mock treatment 1071390.0 -93600.0 -0.46 1259730.0 136000.0 0.81 1150400.0 68457.66666667 0.392090767005035 0.4295 0.4257 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N01 compound treatment 1074340.0 -90700.0 -0.44 1149920.0 26300.0 0.16 1047680.0 -34262.33333333 -0.196237254498598 -0.2788 -0.5476 1253244 Maybridge1_002927 O=C1CCC(=O)N1CN2CCC(CCCC3CCN(CN4C(=O)CCC4=O)CC3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N02 compound treatment 1054350.0 -111000.0 -0.54 1023640.0 -100000.0 -0.59 978100.0 -103842.33333333 -0.594756177164319 -0.9989 -0.999 1953924 Maybridge1_002928 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N03 compound treatment 1208430.0 43400.0 0.21 1220610.0 97000.0 0.58 1094330.0 12387.66666667 0.0709502669494594 0.4964 0.8025 1953925 Maybridge1_002929 S=C(NC1CC2CC1C=C2)N3CCN(CC3)C(=S)NC4CC5CC4C=C5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N04 compound treatment 820750.0 -344000.0 -1.68 893870.0 -230000.0 -1.37 796270.0 -285672.33333333 -1.63618612410752 -2.7046 -0.996 1953926 Maybridge1_002930 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)c2cccs2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N05 compound treatment 1348800.0 184000.0 0.9 1314910.0 191000.0 1.14 1199370.0 117427.66666667 0.672566070870231 1.5634 0.9786 1953927 Maybridge1_002931 Fc1ccccc1NC(=O)C(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N06 compound treatment 1199170.0 34100.0 0.17 1115750.0 -7870.0 -0.05 1196910.0 114967.66666667 0.658476439514128 0.4495 0.6601 1662233 Maybridge1_002932 Cc1onc(c1C(=O)NC2CCN(Cc3ccccc3)CC2)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N07 compound treatment 1079040.0 -86000.0 -0.42 1131520.0 7900.0 0.05 1086090.0 4147.66666667 0.0237557293989343 -0.2017 -0.4765 1953928 Maybridge1_002933 COc1ccc(CCNC(=O)c2ccc(CSc3ccc(Cl)cc3)o2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N08 compound treatment 1264240.0 99200.0 0.48 1377190.0 254000.0 1.51 1281410.0 199467.66666667 1.14244954910386 1.81 0.9268 1953929 Maybridge1_002934 Cc1nn(C(=O)c2c(C)onc2c3c(Cl)cccc3Cl)c(C)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N09 compound treatment 1330820.0 166000.0 0.81 1412040.0 288000.0 1.72 1271400.0 189457.66666667 1.08511734996784 2.0844 0.9539 1923332 Maybridge1_002935 Cc1onc(c1C(=O)N)c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N10 compound treatment 975100.0 -190000.0 -0.93 908040.0 -216000.0 -1.28 900810.0 -181132.33333333 -1.03743406639734 -1.8749 -0.9908 1953930 Maybridge1_002936 [O-][N+](=O)c1cccc(Cl)c1SCc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N11 compound treatment 1407120.0 242000.0 1.18 1568720.0 445000.0 2.65 1356420.0 274477.66666667 1.57206875561659 3.1187 0.9457 1953931 Maybridge1_002937 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N12 compound treatment 1499250.0 334000.0 1.63 1431840.0 308000.0 1.83 1320120.0 238177.66666667 1.36416078072774 2.7886 0.993 1953932 Maybridge1_002938 CC(C)(C)n1cnnc1Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N13 compound treatment 1089630.0 -75400.0 -0.37 996550.0 -127000.0 -0.76 980680.0 -101262.33333333 -0.579979246717674 -0.9838 -0.9633 1953933 Maybridge1_002939 Cc1onc(c1C(=O)NOC(=O)c2cccs2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N14 compound treatment 960850.0 -204000.0 -1.0 991300.0 -132000.0 -0.79 906470.0 -175472.33333333 -1.00501645929346 -1.6105 -0.9941 1621185 Maybridge1_002940 OC1C(=O)Nc2ccc(Br)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N15 compound treatment 1582560.0 418000.0 2.04 1472960.0 349000.0 2.08 1345340.0 263397.66666667 1.50860813958991 3.2481 0.9905 1953934 Maybridge1_002941 CC1N=C(SCc2c(F)cccc2Cl)N3C(C)N=C(SCc4c(F)cccc4Cl)N13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N16 compound treatment 780820.0 -384000.0 -1.88 904570.0 -219000.0 -1.3 784240.0 -297702.33333333 -1.70508785793432 -2.8203 -0.9892 1953935 Maybridge1_002942 Cc1cc(Br)c(NC(=O)c2ccc(Cl)cc2)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N17 compound treatment 945460.0 -220000.0 -1.07 956640.0 -167000.0 -0.99 953860.0 -128082.33333333 -0.733590593453728 -1.6162 -0.9882 1276809 Maybridge1_002943 Fc1cccc(NC2CCN(Cc3ccccc3)CC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N18 compound treatment 1365320.0 200000.0 0.98 1292820.0 169000.0 1.01 68700.0 -1013242.33333333 -5.80333778498562 -2.2047 -0.3693 1953936 Maybridge1_002944 CCOC(=O)NN(C(=O)OCC)c1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N19 compound treatment 1226580.0 61600.0 0.3 1192640.0 69000.0 0.41 1116610.0 34667.66666667 0.198558798093355 0.5252 0.9616 1953937 Maybridge1_002945 CS/C(=N\C(C)(C)CO)/Nc1c(C)cccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N20 compound treatment 1316090.0 151000.0 0.74 1364340.0 241000.0 1.43 1279450.0 197507.66666667 1.13122366395834 1.9057 0.9683 1953938 Maybridge1_002946 Cc1onc(c1C(=O)OCCOc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N21 compound treatment 679150.0 -486000.0 -2.37 709400.0 -414000.0 -2.46 710470.0 -371472.33333333 -2.12760497384478 -4.0211 -0.9981 1953939 Maybridge1_002947 Clc1cc(Cl)cc(c1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N22 compound treatment 1145150.0 -19900.0 -0.1 1068560.0 -55100.0 -0.33 1081730.0 -212.333333329996 -0.00121613755741149 -0.2458 -0.7197 1953940 Maybridge1_002948 Cc1cc(cc(C)c1F)S(=O)(=O)Oc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N23 mock treatment 1400400.0 235000.0 1.15 1322180.0 199000.0 1.18 1359700.0 277757.66666667 1.59085493075806 2.2641 0.9884 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 N24 mock treatment 1220840.0 55800.0 0.27 1130000.0 6380.0 0.04 1185500.0 103557.66666667 0.593125750988461 0.5218 0.7979 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O01 compound treatment 1031470.0 -134000.0 -0.65 984970.0 -139000.0 -0.82 889670.0 -192272.33333333 -1.10123833196929 -1.4886 -0.9776 1560876 Maybridge1_002949 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O02 compound treatment 1052840.0 -112000.0 -0.55 1098240.0 -25400.0 -0.15 1051430.0 -30512.33333333 -0.174759157919173 -0.5045 -0.8482 1953941 Maybridge1_002950 CN(C)C(=S)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O03 compound treatment 1205510.0 40500.0 0.2 1218900.0 95300.0 0.57 1174520.0 92577.66666667 0.530237884203902 0.7474 0.9334 1339604 Maybridge1_002951 COc1ccc(OC)c(c1)C(=O)c2ccc(N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O04 compound treatment 1332170.0 167000.0 0.82 1206940.0 83300.0 0.5 1194340.0 112397.66666667 0.643756783991694 1.1292 0.9803 1953942 Maybridge1_002952 Cc1nnc(s1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O05 compound treatment 1150880.0 -14100.0 -0.07 955270.0 -168000.0 -1.0 1024690.0 -57252.33333333 -0.327912305261532 -0.8072 -0.7646 1649462 Maybridge1_002953 Cc1cc(C)c(NC(=O)C2C(C3CC2C=C3)C(=O)O)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O06 compound treatment 808000.0 -357000.0 -1.74 832980.0 -291000.0 -1.73 763520.0 -318422.33333333 -1.82376150090117 -3.0579 -0.9997 1953943 Maybridge1_002954 COc1cc(cc(c1)C(F)(F)F)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O07 compound treatment 1235420.0 70400.0 0.34 1401280.0 278000.0 1.65 1378140.0 296197.66666667 1.69646989100462 2.1313 0.8909 1953944 Maybridge1_002955 Fc1ccc(cc1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O08 compound treatment 454420.0 -711000.0 -3.47 612810.0 -511000.0 -3.04 378400.0 -703542.33333333 -4.0295333821461 -6.0847 -0.9934 1232106 Maybridge1_002956 CCOC(=O)C(C(Nc1ccc(Cl)c(Cl)c1)c2ccccn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O09 compound treatment 1308030.0 143000.0 0.7 1231840.0 108000.0 0.64 1146150.0 64207.66666667 0.367748924215019 0.9872 0.9692 1953945 Maybridge1_002957 CCN(CC)C(=S)Nc1cccc(SC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O10 compound treatment 712510.0 -453000.0 -2.21 715950.0 -408000.0 -2.42 775840.0 -306102.33333333 -1.75319879427223 -3.6883 -0.9915 1953946 Maybridge1_002958 COc1ccc(cc1CC#N)/C(=N/Nc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O11 compound treatment 1292390.0 127000.0 0.62 1274360.0 151000.0 0.9 1181790.0 99847.66666667 0.571876754105883 1.207 0.9797 1953947 Maybridge1_002959 Fc1ccc(NC(=S)NNC(=O)CC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O12 compound treatment 1184210.0 19200.0 0.09 1271120.0 147000.0 0.88 1036250.0 -45692.33333333 -0.261702492872688 0.4094 0.445 1953948 Maybridge1_002960 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O13 compound treatment 1178490.0 13500.0 0.07 1038080.0 -85500.0 -0.51 992980.0 -88962.33333333 -0.509531089937157 -0.5499 -0.7606 1953949 Maybridge1_002961 COCCCNC1=C(C#N)C(=O)NC(S1)c2ccc(O)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O14 compound treatment 1390810.0 226000.0 1.1 1338080.0 214000.0 1.28 1191070.0 109127.66666667 0.625027883774435 1.734 0.9643 1953950 Maybridge1_002962 [O-][N+](=O)c1c(cc(cc1C(F)(F)F)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O15 compound treatment 1111930.0 -53100.0 -0.26 1166180.0 42600.0 0.25 1117120.0 35177.66666667 0.201479819228157 0.1127 0.2717 1953951 Maybridge1_002963 COC(=O)c1c(C)onc1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O16 compound treatment 1291680.0 127000.0 0.62 1397180.0 274000.0 1.63 1270830.0 188887.66666667 1.08185267928777 1.9211 0.9374 1249654 Maybridge1_002964 Fc1cccc(F)c1NC(=O)c2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O17 compound treatment 672480.0 -493000.0 -2.41 591000.0 -533000.0 -3.17 603480.0 -478462.33333333 -2.74038938798686 -4.8002 -0.9937 1953952 Maybridge1_002965 COCCCNC(=S)N/N=C/c1ccccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O18 compound treatment 1262340.0 97300.0 0.48 1165890.0 42300.0 0.25 1076430.0 -5512.33333333 -0.0315718473896667 0.4014 0.7451 1953953 Maybridge1_002966 Fc1cccc(F)c1NC(=O)CSc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O19 compound treatment 903570.0 -261000.0 -1.28 819450.0 -304000.0 -1.81 793460.0 -288482.33333333 -1.65228037781104 -2.7358 -0.9902 1953954 Maybridge1_002967 COCCCNC(=S)N/N=C/c1ccc(cc1)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O20 compound treatment 925490.0 -240000.0 -1.17 1004410.0 -119000.0 -0.71 869500.0 -212442.33333333 -1.21676185410449 -1.7875 -0.9762 1576501 Maybridge1_002968 CSc1cccc(NCN2C(=O)CCC2=O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O21 compound treatment 828100.0 -337000.0 -1.65 858300.0 -265000.0 -1.58 736040.0 -345902.33333333 -1.98115299263521 -3.0052 -0.9949 1953955 Maybridge1_002969 COc1cc(NC(=O)c2c(C)onc2c3ccccc3Cl)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O22 compound treatment 1061080.0 -104000.0 -0.51 1011680.0 -112000.0 -0.67 1017870.0 -64072.33333333 -0.366973803573981 -0.8894 -0.9729 1953956 Maybridge1_002970 Cc1onc(c1NC(=O)O/N=C(\N)/c2ccc(Cl)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O23 mock treatment 1322340.0 157000.0 0.77 1247480.0 124000.0 0.74 1219730.0 137787.66666667 0.789177816565461 1.3246 0.9996 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 O24 mock treatment 1020510.0 -145000.0 -0.71 982480.0 -141000.0 -0.84 1023690.0 -58252.33333333 -0.333639797682712 -1.0849 -0.9463 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P01 compound treatment 885600.0 -279000.0 -1.37 863890.0 -260000.0 -1.54 752990.0 -328952.33333333 -1.8840719960962 -2.7677 -0.9911 1143543 Maybridge1_002971 Cc1cc(Cl)ccc1NCN2C(=O)CCC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P02 compound treatment 953860.0 -211000.0 -1.03 1075320.0 -48300.0 -0.29 933710.0 -148232.33333333 -0.84899956574051 -1.2517 -0.9159 1468836 Maybridge1_002972 Cc1ccc2N(CCCc2c1)S(=O)(=O)c3c(C)c(C)c(C)c(C)c3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P03 compound treatment 1118280.0 -46700.0 -0.23 1144480.0 20900.0 0.12 1056000.0 -25942.33333333 -0.148584517554379 -0.146 -0.4878 1953957 Maybridge1_002973 FC(F)(F)c1cc(/C=C/C#N)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P04 compound treatment 1228590.0 63600.0 0.31 1295390.0 172000.0 1.02 1079860.0 -2082.33333333 -0.0119265483850185 0.7621 0.7138 1953958 Maybridge1_002974 CC(=N)NS(=O)(=O)c1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P05 compound treatment 1285560.0 121000.0 0.59 1379250.0 256000.0 1.52 1024650.0 -57292.33333333 -0.328141404958379 1.0282 0.6183 1953959 Maybridge1_002975 FC(F)(F)c1cc(/C=C/c2noc(CN3CCCC3)n2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P06 compound treatment 1044480.0 -121000.0 -0.59 944000.0 -180000.0 -1.07 968520.0 -113422.33333333 -0.649625554559226 -1.3318 -0.9637 1953960 Maybridge1_002976 CC(=O)c1ccccc1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P07 compound treatment 1193610.0 28600.0 0.14 1190420.0 66800.0 0.4 1122850.0 40907.66666667 0.23429835080152 0.4452 0.924 1953961 Maybridge1_002977 COc1ccc(OC)c(c1)S(=O)(=O)Oc2ccc(C#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P08 compound treatment 1186790.0 21800.0 0.11 1234210.0 111000.0 0.66 1091940.0 9997.66666667 0.0572615600628387 0.4741 0.7091 1299890 Maybridge1_002978 Clc1ccc(NC(=O)Nc2cccc(Cl)c2C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P09 compound treatment 1201410.0 36400.0 0.18 1217210.0 93600.0 0.56 1098810.0 16867.66666667 0.0966094329963469 0.4797 0.8101 1953962 Maybridge1_002979 CCN(CC)CCNC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P10 compound treatment 1104350.0 -60700.0 -0.3 1049820.0 -73800.0 -0.44 954560.0 -127382.33333333 -0.729581348758902 -0.8458 -0.9381 1953963 Maybridge1_002980 Cc1nn(c(C)c1Cc2c(F)cccc2Cl)S(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P11 compound treatment 966100.0 -199000.0 -0.97 1099360.0 -24300.0 -0.14 849510.0 -232432.33333333 -1.33125442760389 -1.413 -0.854 1953964 Maybridge1_002981 Fc1cccc(Cl)c1CSCc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P12 compound treatment 1026530.0 -138000.0 -0.68 1160280.0 36700.0 0.22 1138500.0 56557.66666667 0.32393360719299 -0.0778 -0.0996 1953965 Maybridge1_002982 CN(C)/C=N/c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P13 compound treatment 1109140.0 -55900.0 -0.27 1277390.0 154000.0 0.91 1089920.0 7977.66666667 0.0456920253720546 0.3967 0.4152 1953966 Maybridge1_002983 NNC(=O)c1snnc1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P14 compound treatment 1059360.0 -106000.0 -0.52 1017940.0 -106000.0 -0.63 930640.0 -151302.33333333 -0.866582967473533 -1.1612 -0.9771 1953967 Maybridge1_002984 Nc1nnc(Sc2ncccc2[N+](=O)[O-])s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P15 compound treatment 1188250.0 23200.0 0.11 1341760.0 218000.0 1.3 1081940.0 -2.33333332999609 -1.33641489636399E-5 0.8144 0.6255 1953968 Maybridge1_002985 CC1N=C(SC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)N4C(C)N=C(SC(=O)c5c(C)onc5c6c(Cl)cccc6Cl)N14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P16 compound treatment 1262720.0 97700.0 0.48 1145640.0 22000.0 0.13 1087810.0 5867.66666667 0.0336070163633643 0.3706 0.747 1953969 Maybridge1_002986 Cc1onc(c1C(=O)N2CCSCC2)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P17 compound treatment 1196480.0 31500.0 0.15 1165080.0 41500.0 0.25 1048740.0 -33202.33333333 -0.190166112532147 0.1213 0.3493 1726756 Maybridge1_002987 Oc1cc(nn1CCC#N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P18 compound treatment 988900.0 -176000.0 -0.86 1062640.0 -61000.0 -0.36 1034480.0 -47462.33333333 -0.271840154458177 -0.8631 -0.8875 1953970 Maybridge1_002988 [O-][N+](=O)c1cc(C#N)ccc1Sc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P19 compound treatment 869390.0 -296000.0 -1.44 867760.0 -256000.0 -1.52 858570.0 -223372.33333333 -1.27936334626799 -2.451 -0.9975 1466399 Maybridge1_002989 Clc1ccc(NCc2cccnc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P20 compound treatment 865280.0 -300000.0 -1.46 825530.0 -298000.0 -1.77 775890.0 -306052.33333333 -1.75291241965117 -2.881 -0.9964 1953971 Maybridge1_002990 Cc1c(nnn1c2cc(Cl)cc(Cl)c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P21 compound treatment 1143570.0 -21500.0 -0.1 1086630.0 -37000.0 -0.22 1087700.0 5757.66666667 0.0329769921970345 -0.1685 -0.6852 1953972 Maybridge1_002991 NC(=N)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P22 compound treatment 1000070.0 -165000.0 -0.81 1118290.0 -5330.0 -0.03 1069460.0 -12482.33333333 -0.0714924695652929 -0.5249 -0.6482 1953973 Maybridge1_002992 CC(C)(C)SCCNC(=O)/C=C/c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P23 mock treatment 1256090.0 91100.0 0.44 1241440.0 118000.0 0.7 1203710.0 121767.66666667 0.697423387978153 1.064 0.9815 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1232 P24 mock treatment 1111940.0 -53100.0 -0.26 1069600.0 -54000.0 -0.32 818650.0 -263292.33333333 -1.50800484372151 -1.2059 -0.7713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A01 compound treatment 528980.0 -530000.0 -2.59 518000.0 -528000.0 -3.14 468600.0 -578390.64516129 -3.31272803664283 -5.2201 -0.9948 1 Bio1_000001 Oc1ccc(/C=C(\C#N)/C(=O)NCCCNC(=O)\C(=C\c2ccc(O)c(O)c2)\C#N)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A02 compound treatment 844160.0 -215000.0 -1.05 955170.0 -90500.0 -0.54 849770.0 -197220.64516129 -1.12957975046156 -1.5697 -0.9606 2 Bio1_000002 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A03 compound treatment 373570.0 -686000.0 -3.35 359280.0 -686000.0 -4.08 166190.0 -880800.64516129 -5.04477901973195 -7.2034 -0.9864 3 Bio1_000003 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A04 compound treatment 984640.0 -74600.0 -0.36 994360.0 -51300.0 -0.31 786020.0 -260970.64516129 -1.4947073923118 -1.2497 -0.7967 4 Bio1_000004 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A05 compound treatment 585410.0 -474000.0 -2.32 571360.0 -474000.0 -2.82 448350.0 -598640.64516129 -3.42870975817173 -4.9447 -0.9875 5 Bio1_000005 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A06 compound treatment 1105760.0 46500.0 0.23 1042260.0 -3410.0 -0.02 910750.0 -136240.64516129 -0.780317262617994 -0.3311 -0.4073 6 Bio1_000006 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A07 compound treatment 507040.0 -552000.0 -2.7 520320.0 -525000.0 -3.12 422020.0 -624970.64516129 -3.57951463362141 -5.4281 -0.9935 7 Bio1_000007 CC[C@H](Nc1nc(Nc2cccc(Cl)c2)c3ncn(C(C)C)c3n1)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A08 compound treatment 1090480.0 31200.0 0.15 1204100.0 158000.0 0.94 864240.0 -182750.64516129 -1.04670293512709 0.0276 0.0195 8 Bio1_000008 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A09 compound treatment 470320.0 -589000.0 -2.88 437800.0 -608000.0 -3.61 340660.0 -706330.64516129 -4.04550341700863 -6.084 -0.9907 9 Bio1_000009 [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc34)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A10 compound treatment 1117140.0 57900.0 0.28 1241050.0 195000.0 1.16 901600.0 -145390.64516129 -0.832723818271793 0.3532 0.2424 10 Bio1_000010 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A11 compound treatment 1112260.0 53000.0 0.26 1064800.0 19100.0 0.11 835330.0 -211660.64516129 -1.21228474102341 -0.4848 -0.3894 11 Bio1_000011 C/C(=C\CCC1=CCC(OC1O)C2=CC(=O)OC2O)/CCC3=C(C)CCCC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A12 compound treatment 1207250.0 148000.0 0.72 1197440.0 152000.0 0.9 825870.0 -221120.64516129 -1.26646681932777 0.2073 0.1209 12 Bio1_000012 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N4CCOCC4)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A13 compound treatment 1104640.0 45400.0 0.22 1181240.0 136000.0 0.81 892580.0 -154410.64516129 -0.884385799910838 0.0828 0.068 13 Bio1_000013 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A14 compound treatment 1124450.0 65200.0 0.32 1231750.0 186000.0 1.11 898560.0 -148430.64516129 -0.850135395232181 0.3319 0.2319 14 Bio1_000014 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A15 compound treatment 1130580.0 71300.0 0.35 1079840.0 34200.0 0.2 895740.0 -151250.64516129 -0.866286923859909 -0.1817 -0.1902 1000000 Bio1_000015 CCCCC/C=C\C/C=C\C/C=C\C=C\C(O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A16 compound treatment 1135960.0 76700.0 0.37 1097320.0 51700.0 0.31 873130.0 -173860.64516129 -0.995785527502794 -0.1813 -0.1637 1000001 Bio1_000016 CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(cc32)C(=O)O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A17 compound treatment 1189470.0 130000.0 0.64 1122010.0 76300.0 0.45 828320.0 -218670.64516129 -1.25243446289588 -0.0937 -0.0635 17 Bio1_000017 CCCCC/C=C\C/C=C\C/C=C\C=C\C1CCCC(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A18 compound treatment 1084640.0 25400.0 0.12 1164830.0 119000.0 0.71 790690.0 -256300.64516129 -1.46796000270489 -0.3669 -0.2244 18 Bio1_000018 Cc1c(C(=O)c2ccc3ccccc3c2)c4cccc5OC[C@@H](CN6CCOCC6)n1c54 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A19 compound treatment 1077570.0 18300.0 0.09 1151620.0 106000.0 0.63 927040.0 -119950.64516129 -0.687016411076968 0.0187 0.02 19 Bio1_000019 CCCCC/C=C\C/C=C\C=C\[C@@H](O)C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A20 compound treatment 1167410.0 108000.0 0.53 1130730.0 85100.0 0.51 863330.0 -183660.64516129 -1.05191495323036 -0.0103 -0.008 20 Bio1_000020 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A21 compound treatment 1083430.0 24100.0 0.12 1104960.0 59300.0 0.35 852960.0 -194030.64516129 -1.111309049638 -0.3699 -0.3157 21 Bio1_000021 CCCCC/C=C\C/C=C\C[C@H](O)/C=C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A22 compound treatment 1011050.0 -48200.0 -0.24 1006310.0 -39400.0 -0.23 869510.0 -177480.64516129 -1.01651905006747 -0.8581 -0.8024 22 Bio1_000022 CCCCC/C=C\C/C=C\CCCCCCCC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A23 mock treatment 1026110.0 -33200.0 -0.16 1087580.0 41900.0 0.25 902910.0 -144080.64516129 -0.825220803200047 -0.4261 -0.4858 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 A24 mock treatment 890000.0 -169000.0 -0.83 1064960.0 19300.0 0.11 881140.0 -165850.64516129 -0.94990831320914 -0.9597 -0.7588 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B01 compound treatment 1130620.0 71300.0 0.35 1008510.0 -37200.0 -0.22 991410.0 -55580.64516129 -0.318337723925596 -0.1101 -0.2113 23 Bio1_000023 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B02 compound treatment 432130.0 -627000.0 -3.06 386560.0 -659000.0 -3.92 251460.0 -795530.64516129 -4.55639574097791 -6.6626 -0.9876 24 Bio1_000024 CN(CCc1ccc(Cl)c(Cl)c1)CC(O)COc2ccc(NS(=O)(=O)C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B03 compound treatment 1076240.0 17000.0 0.08 1013440.0 -32200.0 -0.19 915530.0 -131460.64516129 -0.752939848844752 -0.4975 -0.6367 25 Bio1_000025 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)OCC[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B04 compound treatment 218680.0 -841000.0 -4.11 222480.0 -823000.0 -4.9 187470.0 -859520.64516129 -4.92289798100923 -8.0396 -0.9967 26 Bio1_000026 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B05 compound treatment 1050280.0 -9000.0 -0.04 1045020.0 -648.0 0.0 878720.0 -168270.64516129 -0.963768844868396 -0.584 -0.6054 27 Bio1_000027 CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B06 compound treatment 194720.0 -865000.0 -4.22 154100.0 -892000.0 -5.3 140960.0 -906030.64516129 -5.18928365351832 -8.4958 -0.9952 28 Bio1_000028 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B07 compound treatment 1156220.0 96900.0 0.47 1082890.0 37200.0 0.22 882780.0 -164210.64516129 -0.940515225638405 -0.1418 -0.1317 29 Bio1_000029 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NCCCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B08 compound treatment 1120400.0 61100.0 0.3 1076110.0 30400.0 0.18 900160.0 -146830.64516129 -0.840971407358292 -0.2086 -0.2291 30 Bio1_000030 COC(=O)C1=C(C)NC(=C(C1c2ccccc2C(F)(F)F)[N+](=O)[O-])C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B09 compound treatment 1193060.0 134000.0 0.65 1134630.0 89000.0 0.53 982470.0 -64520.64516129 -0.369541506170947 0.4694 0.5111 31 Bio1_000031 CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B10 compound treatment 824640.0 -235000.0 -1.15 876770.0 -169000.0 -1.0 604160.0 -442830.64516129 -2.53630916402764 -2.7061 -0.9145 32 Bio1_000032 C/C(=C/1\C(=O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O)/O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B11 compound treatment 1199530.0 140000.0 0.69 1144050.0 98400.0 0.59 896870.0 -150120.64516129 -0.859814857423975 0.237 0.1903 33 Bio1_000033 CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B12 compound treatment 1145870.0 86600.0 0.42 1145080.0 99400.0 0.59 877140.0 -169850.64516129 -0.972818282893861 0.0239 0.0197 3000787 Bio1_000034 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B13 compound treatment 1358080.0 299000.0 1.46 1223450.0 178000.0 1.06 980650.0 -66340.64516129 -0.379965542377495 1.2339 0.6698 34 Bio1_000035 CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B14 compound treatment 1406880.0 348000.0 1.7 1296200.0 251000.0 1.49 969230.0 -77760.64516129 -0.445373505827374 1.5835 0.6877 35 Bio1_000036 CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B15 compound treatment 1400550.0 341000.0 1.67 1189690.0 144000.0 0.86 957920.0 -89070.64516129 -0.510151445110922 1.1626 0.5985 36 Bio1_000037 CCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B16 compound treatment 1416320.0 357000.0 1.74 1283200.0 238000.0 1.41 948410.0 -98580.64516129 -0.564619898036346 1.4967 0.6466 37 Bio1_000038 Nc1nc(N)c(nc1Cl)C(=O)NC(=C)NCc2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B17 compound treatment 1216370.0 157000.0 0.77 1075400.0 29700.0 0.18 974920.0 -72070.64516129 -0.412784073950858 0.3069 0.3451 1000002 Bio1_000039 CCCCCCCCCCCCCC(=O)N[C@@H](C)[C@H](O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B18 compound treatment 103400.0 -956000.0 -4.67 75700.0 -970000.0 -5.77 43090.0 -1003900.64516129 -5.74983333677923 -9.3462 -0.9955 39 Bio1_000040 Nc1c(S(=O)C(F)(F)F)c(C#N)nn1c2c(Cl)cc(cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B19 compound treatment 1119850.0 60600.0 0.3 1120720.0 75100.0 0.45 827200.0 -219790.64516129 -1.2588492544076 -0.2983 -0.218 40 Bio1_000041 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B20 compound treatment 1176530.0 117000.0 0.57 1096660.0 51000.0 0.3 815860.0 -231130.64516129 -1.32379901846379 -0.2585 -0.1754 41 Bio1_000042 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B21 compound treatment 1245520.0 186000.0 0.91 1279530.0 234000.0 1.39 927610.0 -119380.64516129 -0.683751740396895 0.9335 0.5195 42 Bio1_000043 CCCCCCCCCCCCCCCCOC[C@@H](O)COP(=O)(O)OCC[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B22 compound treatment 628810.0 -430000.0 -2.1 566250.0 -479000.0 -2.85 569280.0 -477710.64516129 -2.73608409967841 -4.4399 -0.9919 43 Bio1_000044 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B23 mock treatment 1157670.0 98400.0 0.48 1122460.0 76800.0 0.46 1007310.0 -39680.64516129 -0.22727059442883 0.41 0.5849 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 B24 mock treatment 997010.0 -62300.0 -0.3 1128960.0 83300.0 0.5 993800.0 -53190.64516129 -0.304649017038975 -0.0656 -0.0999 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C01 compound treatment 945120.0 -114000.0 -0.56 956270.0 -89400.0 -0.53 1012970.0 -34020.64516129 -0.19485298732495 -0.7415 -0.9329 44 Bio1_000045 CCCCC/C=C\C=C\[C@@H](O)C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C02 compound treatment 1081510.0 22200.0 0.11 1014190.0 -31500.0 -0.19 948090.0 -98900.64516129 -0.566452695611124 -0.3724 -0.6141 45 Bio1_000046 CCCCCCCC/C=C\CCCCCCCC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C03 compound treatment 1102050.0 42800.0 0.21 1072480.0 26800.0 0.16 1004320.0 -42670.64516129 -0.244395796768159 0.0716 0.1995 46 Bio1_000047 CCCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C04 compound treatment 1126490.0 67200.0 0.33 1127000.0 81300.0 0.48 922460.0 -124530.64516129 -0.713248326365973 0.057 0.0618 47 Bio1_000048 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C05 compound treatment 1116800.0 57500.0 0.28 1145670.0 100000.0 0.59 951430.0 -95560.64516129 -0.547322870924382 0.1896 0.2216 1000003 Bio1_000049 CCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C06 compound treatment 1237950.0 179000.0 0.87 1125120.0 79500.0 0.47 1005080.0 -41910.64516129 -0.240042902528062 0.6382 0.6249 49 Bio1_000050 COC(=O)[C@@H](N)CSC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C07 compound treatment 1204870.0 146000.0 0.71 1216750.0 171000.0 1.02 962340.0 -84650.64516129 -0.484835928609305 0.7181 0.5389 50 Bio1_000051 CCCCC[C@H](O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C08 compound treatment 1374080.0 315000.0 1.54 1109380.0 63700.0 0.38 967220.0 -79770.64516129 -0.456885765593946 0.843 0.5113 51 Bio1_000052 CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C09 compound treatment 1208990.0 150000.0 0.73 1146140.0 100000.0 0.6 1057600.0 10609.35483871 0.0607649994323236 0.8023 0.8478 52 Bio1_000053 CCCCC[C@H](O)/C=C/C=C\CCCCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C10 compound treatment 1243540.0 184000.0 0.9 1203040.0 157000.0 0.94 941300.0 -105690.64516129 -0.605342369150937 0.7106 0.496 53 Bio1_000054 CC(=CCC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C11 compound treatment 1536130.0 477000.0 2.33 1437880.0 392000.0 2.33 918850.0 -128140.64516129 -0.733924574006434 2.2679 0.6715 54 Bio1_000055 CCCCCCCC/C=C\C/C=C\C=C\C(O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C12 compound treatment 1378260.0 319000.0 1.56 1268590.0 223000.0 1.33 918240.0 -128750.64516129 -0.737418344383354 1.2394 0.5699 55 Bio1_000056 CC(=CCC/C(=C/CC/C(=C/CSCC(=O)O)/C)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C13 compound treatment 994490.0 -64800.0 -0.32 998430.0 -47200.0 -0.28 869520.0 -177470.64516129 -1.01646177514325 -0.9318 -0.8463 56 Bio1_000057 CCCCC/C=C\C[C@@H](O)/C=C/C=C\CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C14 compound treatment 1407720.0 348000.0 1.7 1254240.0 209000.0 1.24 953200.0 -93790.64516129 -0.537185209338893 1.3888 0.6389 57 Bio1_000058 CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C15 compound treatment 1354560.0 295000.0 1.44 1253440.0 208000.0 1.24 908710.0 -138280.64516129 -0.792001347157201 1.089 0.5292 58 Bio1_000059 CCCCC[C@H](O)/C=C/C=C\C/C=C\CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C16 compound treatment 1306970.0 248000.0 1.21 1303200.0 258000.0 1.53 929480.0 -117510.64516129 -0.673041329569288 1.1943 0.5784 1000004 Bio1_000060 CCCCC/C=C\C=C\C(O)CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C17 compound treatment 1315800.0 257000.0 1.25 1134290.0 88600.0 0.53 914740.0 -132250.64516129 -0.757464567857484 0.5905 0.3794 60 Bio1_000061 CC/C=C\C/C=C\C/C=C\C/C=C\C=C\C(O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C18 compound treatment 1381920.0 323000.0 1.58 1175420.0 130000.0 0.77 906260.0 -140730.64516129 -0.806033703589093 0.8902 0.4609 61 Bio1_000062 CCCCC[C@H](O)/C=C/C=C\CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C19 compound treatment 1314720.0 255000.0 1.25 1343770.0 298000.0 1.77 988980.0 -58010.64516129 -0.332255530509064 1.5522 0.7077 62 Bio1_000063 CC/C=C\C[C@H](O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C20 compound treatment 1292880.0 234000.0 1.14 1223170.0 178000.0 1.06 961170.0 -85820.64516129 -0.491537094742086 0.9846 0.6039 1000005 Bio1_000064 CCCCCC(O)/C=C/C=C\CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C21 compound treatment 1273860.0 215000.0 1.05 1216900.0 171000.0 1.02 1117760.0 70769.35483871 0.405330943490526 1.4272 0.941 64 Bio1_000065 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)OO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C22 compound treatment 1256800.0 198000.0 0.97 1284450.0 239000.0 1.42 937800.0 -109190.64516129 -0.625388592625068 1.0159 0.556 65 Bio1_000066 CCCCC[C@H](O)/C=C/C=C\C/C=C\CCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C23 mock treatment 1075840.0 16600.0 0.08 1034910.0 -10800.0 -0.06 992350.0 -54640.64516129 -0.312953881049687 -0.1709 -0.5187 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 C24 mock treatment 1027570.0 -31700.0 -0.15 1116400.0 70700.0 0.42 912270.0 -134720.64516129 -0.7716114741378 -0.2921 -0.3273 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D01 compound treatment 918440.0 -141000.0 -0.69 980640.0 -65000.0 -0.39 926210.0 -120780.64516129 -0.691770229786547 -1.0199 -0.9718 66 Bio1_000067 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D02 compound treatment 1100680.0 41400.0 0.2 1005600.0 -40100.0 -0.24 915050.0 -131940.64516129 -0.755689045206918 -0.4571 -0.5589 3104253 Bio1_000068 CC(CCCN1CCC2(CC1)N(C)CNC2=O)c3ccc(F)cc3.Fc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D03 compound treatment 1123710.0 64400.0 0.31 1210270.0 165000.0 0.98 968320.0 -78670.64516129 -0.450585523930648 0.4867 0.4336 67 Bio1_000069 CCCCCCCCCCCCCCCCCCOC[C@@H](O)COP(=O)(O)OCC[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D04 compound treatment 1130750.0 71500.0 0.35 1124480.0 78800.0 0.47 993700.0 -53290.64516129 -0.305221766281093 0.296 0.4489 68 Bio1_000070 Cc1[nH]c(C)c(C(=O)c2ccccc2Cc3ccccc3)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D05 compound treatment 1020960.0 -38300.0 -0.19 951130.0 -94500.0 -0.56 769890.0 -277100.64516129 -1.58709184506544 -1.349 -0.7963 69 Bio1_000071 CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D06 compound treatment 765120.0 -294000.0 -1.44 851520.0 -194000.0 -1.15 850730.0 -196260.64516129 -1.12408135773723 -2.1453 -0.9936 70 Bio1_000072 CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D07 compound treatment 1260910.0 202000.0 0.99 1228350.0 183000.0 1.09 951710.0 -95280.64516129 -0.545719173046451 0.8809 0.563 1000007 Bio1_000073 CCCCCCCCCCCCCCCCOC[C@@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D08 compound treatment 1286730.0 227000.0 1.11 1242310.0 197000.0 1.17 956960.0 -90030.64516129 -0.515649837835255 1.019 0.6017 72 Bio1_000074 Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D09 compound treatment 1357640.0 298000.0 1.46 1285760.0 240000.0 1.43 989800.0 -57190.64516129 -0.327558986723696 1.4768 0.7146 73 Bio1_000075 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D10 compound treatment 1401050.0 342000.0 1.67 1259290.0 214000.0 1.27 923810.0 -123180.64516129 -0.70551621159738 1.2902 0.5828 74 Bio1_000076 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D11 compound treatment 1200860.0 142000.0 0.69 1160090.0 114000.0 0.68 1017130.0 -29860.64516129 -0.17102661885284 0.6935 0.7039 75 Bio1_000077 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D12 compound treatment 1299200.0 240000.0 1.17 1228390.0 183000.0 1.09 984970.0 -62020.64516129 -0.355222775117997 1.099 0.6712 76 Bio1_000078 CC1(C)[C@@H](O)C[C@@H]2[C@]1(O)[C@H](O)C[C@@]3(C[C@@](C)(O)C4CC[C@H]3[C@@]2(C)O)[C@@H]4O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D13 compound treatment 861770.0 -198000.0 -0.97 832670.0 -213000.0 -1.27 785000.0 -261990.64516129 -1.50054943458141 -2.1548 -0.9848 77 Bio1_000079 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCCCCC/C=C\C/C=C\C/C=C\CCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D14 compound treatment 1349660.0 290000.0 1.42 1278320.0 233000.0 1.38 959750.0 -87240.64516129 -0.499670133980162 1.3294 0.6505 78 Bio1_000080 C[C@]1(Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O)C3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D15 compound treatment 1342560.0 283000.0 1.38 1394190.0 349000.0 2.07 1008350.0 -38640.64516129 -0.221314002310803 1.8679 0.7466 79 Bio1_000081 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D16 compound treatment 105790.0 -953000.0 -4.66 84770.0 -961000.0 -5.71 45780.0 -1001210.64516129 -5.73442638216626 -9.2994 -0.9957 80 Bio1_000082 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D17 compound treatment 1327480.0 268000.0 1.31 1403840.0 358000.0 2.13 921680.0 -125310.64516129 -0.717715770454494 1.5719 0.6042 81 Bio1_000083 CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D18 compound treatment 1384590.0 325000.0 1.59 1216670.0 171000.0 1.02 938880.0 -108110.64516129 -0.619202900810194 1.1472 0.5777 82 Bio1_000084 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D19 compound treatment 1255530.0 196000.0 0.96 1239780.0 194000.0 1.15 992030.0 -54960.64516129 -0.314786678624464 1.0383 0.6772 83 Bio1_000085 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D20 compound treatment 1323220.0 264000.0 1.29 1122780.0 77100.0 0.46 989390.0 -57600.64516129 -0.32990725861638 0.8188 0.5816 84 Bio1_000086 Nc1cc(nc(N)[n+]1OS(=O)(=O)O)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D21 compound treatment 1321940.0 263000.0 1.28 1284320.0 239000.0 1.42 952850.0 -94140.64516129 -0.539189831686306 1.249 0.6283 85 Bio1_000087 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)NC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D22 compound treatment 438890.0 -620000.0 -3.03 355040.0 -691000.0 -4.11 347280.0 -699710.64516129 -4.00758741718042 -6.4349 -0.9916 86 Bio1_000088 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D23 mock treatment 1118250.0 59000.0 0.29 1027300.0 -18400.0 -0.11 998930.0 -48060.64516129 -0.275266980918321 -0.0556 -0.1347 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 D24 mock treatment 1106840.0 47600.0 0.23 1070910.0 25200.0 0.15 1064390.0 17399.35483871 0.0996546729721374 0.2784 0.9467 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E01 compound treatment 1070210.0 10900.0 0.05 1105280.0 59600.0 0.35 988240.0 -58750.64516129 -0.336493874900737 0.0412 0.0838 87 Bio1_000089 CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E02 compound treatment 1046750.0 -12500.0 -0.06 1051910.0 6240.0 0.04 1000840.0 -46150.64516129 -0.264327470393866 -0.1665 -0.6081 88 Bio1_000090 CCCCC/C=C\C=C\[C@H](CCCCCCCC(=O)O)OO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E03 compound treatment 1070290.0 11000.0 0.05 1009880.0 -35800.0 -0.21 1011780.0 -35210.64516129 -0.201668703306155 -0.2082 -0.6986 89 Bio1_000091 CCCCC[C@H](OO)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E04 compound treatment 1276480.0 217000.0 1.06 1181530.0 136000.0 0.81 1003650.0 -43340.64516129 -0.24823321669035 0.9358 0.6898 90 Bio1_000092 CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E05 compound treatment 1255320.0 196000.0 0.96 1240340.0 195000.0 1.16 987200.0 -59790.64516129 -0.342450467018765 1.0236 0.6643 91 Bio1_000093 CCCCC[C@H](OO)/C=C/C=C\CCCCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E06 compound treatment 1262810.0 204000.0 0.99 1310920.0 265000.0 1.58 1045030.0 -1960.64516128995 -0.0112295803019119 1.4783 0.7928 92 Bio1_000094 CCCCC/C=C\CC1OC1CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E07 compound treatment 1367060.0 308000.0 1.5 1272280.0 227000.0 1.35 1041790.0 -5200.64516128995 -0.0297866557465359 1.629 0.8067 93 Bio1_000095 CC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E08 compound treatment 1329460.0 270000.0 1.32 1195840.0 150000.0 0.89 1002270.0 -44720.64516129 -0.256137156231579 1.1298 0.6999 94 Bio1_000096 CCCCCC1OC1C/C=C\CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E09 compound treatment 1294760.0 235000.0 1.15 1230600.0 185000.0 1.1 928190.0 -118800.64516129 -0.68042979479261 0.9063 0.5236 95 Bio1_000097 CCCCCC(O)/C=C/C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E10 compound treatment 1329340.0 270000.0 1.32 1245760.0 200000.0 1.19 1067420.0 20429.35483871 0.117008975008313 1.5163 0.8516 96 Bio1_000098 CCCCC[C@H](O)/C=C/C=C/C\C=C/CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E11 compound treatment 1432700.0 373000.0 1.82 1263700.0 218000.0 1.3 1061450.0 14459.35483871 0.0828158452538675 1.8497 0.8259 97 Bio1_000099 CCCCC/C=C\C[C@@H]1O[C@H]1\C=C\C(O)C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E12 compound treatment 1246080.0 187000.0 0.91 1280480.0 235000.0 1.4 898820.0 -148170.64516129 -0.848646247202674 0.8431 0.4505 98 Bio1_000100 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E13 compound treatment 1333540.0 274000.0 1.34 1389080.0 343000.0 2.04 1033360.0 -13630.64516129 -0.0780694168570852 1.9076 0.7806 99 Bio1_000101 CCCCC/C=C\C[C@@H]1O[C@H]1C(O)/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E14 compound treatment 1326890.0 268000.0 1.31 1252830.0 207000.0 1.23 1009730.0 -37260.64516129 -0.213410062769574 1.3429 0.7423 100 Bio1_000102 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)C[C@H](O)C3=C)/CCC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E15 compound treatment 1409250.0 350000.0 1.71 1338360.0 293000.0 1.74 1008320.0 -38670.64516129 -0.221485827083438 1.8642 0.7609 101 Bio1_000103 OCCCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E16 compound treatment 1168980.0 110000.0 0.54 1142960.0 97300.0 0.58 897340.0 -149650.64516129 -0.85712293598602 0.1486 0.1276 102 Bio1_000104 C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E17 compound treatment 1396540.0 337000.0 1.65 1277000.0 231000.0 1.38 931840.0 -115150.64516129 -0.659524447455302 1.3648 0.6078 103 Bio1_000105 CCCCC[C@H](O)/C=C/C=C\C=C/C=C/[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E18 compound treatment 1414740.0 355000.0 1.74 1487850.0 442000.0 2.63 974110.0 -72880.64516129 -0.417423342812014 2.2798 0.7172 104 Bio1_000106 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E19 compound treatment 1421210.0 362000.0 1.77 1420410.0 375000.0 2.23 1133120.0 86129.35483871 0.493305227079855 2.5923 0.8979 105 Bio1_000107 CCCCC[C@H](O)/C=C/C=C\C=C\[C@@H](O)C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E20 compound treatment 1390630.0 331000.0 1.62 1409600.0 364000.0 2.16 1007580.0 -39410.64516129 -0.225724171475112 2.0538 0.7573 1000008 Bio1_000108 C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E21 compound treatment 1352320.0 293000.0 1.43 1257690.0 212000.0 1.26 1003160.0 -43830.64516129 -0.251039687976728 1.4096 0.7326 107 Bio1_000109 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E22 compound treatment 1314410.0 255000.0 1.25 1290650.0 245000.0 1.46 1088850.0 41859.35483871 0.239749137594206 1.6992 0.8794 1000009 Bio1_000110 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E23 mock treatment 1211310.0 152000.0 0.74 1089180.0 43500.0 0.26 1064570.0 17579.35483871 0.10068562160795 0.6364 0.8025 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 E24 mock treatment 1124350.0 65100.0 0.32 1067200.0 21500.0 0.13 1126660.0 79669.35483871 0.45630562603903 0.5209 0.9128 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F01 compound treatment 1053040.0 -6240.0 -0.03 988400.0 -57300.0 -0.34 904480.0 -142510.64516129 -0.816228640098794 -0.6855 -0.7746 109 Bio1_000111 CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F02 compound treatment 118270.0 -941000.0 -4.6 149640.0 -896000.0 -5.33 136880.0 -910110.64516129 -5.21265182259674 -8.7402 -0.998 110 Bio1_000112 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F03 compound treatment 1047360.0 -11900.0 -0.06 997550.0 -48100.0 -0.29 944520.0 -102470.64516129 -0.586899843554737 -0.5377 -0.8202 111 Bio1_000113 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F04 compound treatment 1035930.0 -23400.0 -0.11 1014620.0 -31000.0 -0.18 1025150.0 -21840.64516129 -0.125092129634975 -0.2447 -0.9768 112 Bio1_000114 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F05 compound treatment 1068160.0 8880.0 0.04 1111200.0 65500.0 0.39 957230.0 -89760.64516129 -0.514103414881536 -0.0468 -0.0724 113 Bio1_000115 CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F06 compound treatment 90050.0 -969000.0 -4.74 75940.0 -970000.0 -5.77 49120.0 -997870.64516129 -5.71529655747952 -9.3631 -0.9962 1000010 Bio1_000116 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCCN3CCC(C)(C)CC3)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F07 compound treatment 1162160.0 103000.0 0.5 1033230.0 -12400.0 -0.07 964290.0 -82700.64516129 -0.473667318388004 -0.026 -0.0374 114 Bio1_000117 CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F08 compound treatment 872560.0 -187000.0 -0.91 1112530.0 66900.0 0.4 938640.0 -108350.64516129 -0.620577498991277 -0.6554 -0.5589 115 Bio1_000118 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F09 compound treatment 1157280.0 98000.0 0.48 1143520.0 97900.0 0.58 981340.0 -65650.64516129 -0.376013572606881 0.3953 0.4694 116 Bio1_000119 Cc1c(nn(c1c2ccc(I)cc2)c3ccc(Cl)cc3Cl)C(=O)NN4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F10 compound treatment 1028230.0 -31100.0 -0.15 907110.0 -139000.0 -0.82 772910.0 -274080.64516129 -1.56979481795348 -1.4696 -0.8259 117 Bio1_000120 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F11 compound treatment 1295970.0 237000.0 1.16 1154150.0 108000.0 0.65 1067430.0 20439.35483871 0.117066249932525 1.1077 0.8333 118 Bio1_000121 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F12 compound treatment 1324970.0 266000.0 1.3 1313280.0 268000.0 1.59 960340.0 -86650.64516129 -0.496290913451666 1.3817 0.654 119 Bio1_000122 OC(=O)c1ccccc1Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F13 compound treatment 1208820.0 150000.0 0.73 1081440.0 35800.0 0.21 1138350.0 91359.35483871 0.523260012442627 0.8467 0.9169 120 Bio1_000123 O=Cc1c2[nH]c3ccccc3c2cc4[nH]c5ccccc5c14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F14 compound treatment 1341510.0 282000.0 1.38 1307140.0 261000.0 1.55 805890.0 -241100.64516129 -1.38090211790295 0.8966 0.3593 121 Bio1_000124 OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F15 compound treatment 1302170.0 243000.0 1.19 1198200.0 153000.0 0.91 905510.0 -141480.64516129 -0.810329322904978 0.741 0.4361 122 Bio1_000125 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F16 compound treatment 905880.0 -153000.0 -0.75 897050.0 -149000.0 -0.88 762930.0 -284060.64516129 -1.62695519231686 -1.8823 -0.9423 3104332 Bio1_000126 Cn1c(=O)[nH]c2cc(ccc12)C(F)(F)F.Oc1ccc(cc1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F17 compound treatment 1418400.0 359000.0 1.75 1508800.0 463000.0 2.75 1109990.0 62999.35483871 0.360828327377956 2.8114 0.8557 123 Bio1_000127 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F18 compound treatment 876330.0 -183000.0 -0.89 909050.0 -137000.0 -0.81 795570.0 -251420.64516129 -1.44000983968953 -1.8165 -0.9665 124 Bio1_000128 CC(C)(O)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@H](Cc5c4[nH]c6ccccc56)CC[C@@]3(O)C2=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F19 compound treatment 491230.0 -568000.0 -2.78 503840.0 -542000.0 -3.22 340000.0 -706990.64516129 -4.04928356200661 -5.8005 -0.9878 125 Bio1_000129 COc1cc(O)c2c(=O)c(OC)c(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5c(CC(C)OC(=O)c6ccccc6)c(OC)c(=O)c7c(O)cc(OC)c(c1c24)c75 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F20 compound treatment 1299650.0 240000.0 1.17 1255360.0 210000.0 1.25 960550.0 -86440.64516129 -0.495088140043218 1.1121 0.6237 126 Bio1_000130 CC1(C)Oc2ccc(C#N)cc2[C@@H](OC3=CC(=O)CC3)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F21 compound treatment 956120.0 -103000.0 -0.5 871940.0 -174000.0 -1.03 721940.0 -325050.64516129 -1.86172510666103 -1.9623 -0.8969 3104393 Bio1_000131 CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F22 compound treatment 125240.0 -934000.0 -4.56 109190.0 -936000.0 -5.57 67300.0 -979690.64516129 -5.61117074526246 -9.0895 -0.9958 128 Bio1_000132 CC(=C)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@@H](CC[C@@]3(O)[C@@]52O[C@@H]5[C@H]1O)[C@@H]6OC(C)(C)[C@H]7C[C@@H]8C(=C)Cc9c(Cl)cc%10[nH]c4c6c%10c9[C@@]87O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F23 mock treatment 1077500.0 18200.0 0.09 1048490.0 2820.0 0.02 1042100.0 -4890.64516128995 -0.02801113309597 0.0449 0.4737 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 F24 mock treatment 1107050.0 47800.0 0.23 1045760.0 92.3 0.0 1021090.0 -25900.64516129 -0.148345748864967 0.0494 0.1787 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G01 compound treatment 1027530.0 -31800.0 -0.16 1039360.0 -6310.0 -0.04 954130.0 -92860.64516129 -0.531858641387195 -0.4183 -0.7533 129 Bio1_000133 CCCCC/C=C\C[C@@H](O)\C=C\C=C\C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G02 compound treatment 1046950.0 -12300.0 -0.06 1050200.0 4530.0 0.03 921960.0 -125030.64516129 -0.716112072576563 -0.4327 -0.6016 130 Bio1_000134 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G03 compound treatment 1042990.0 -16300.0 -0.08 1023260.0 -22400.0 -0.13 969850.0 -77140.64516129 -0.441822460526242 -0.378 -0.8071 1000012 Bio1_000135 CCCCC[C@H](O)/C=C/C=C/C=C/[C@H](O)C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G04 compound treatment 1311310.0 252000.0 1.23 1206680.0 161000.0 0.96 1127250.0 80259.35483871 0.459684846567527 1.5291 0.9403 132 Bio1_000136 CC1(C)CCC(C)(C)c2cc(ccc21)C(=O)Nc3ccc(cc3)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G05 compound treatment 1148080.0 88800.0 0.43 1121340.0 75700.0 0.45 1093440.0 46449.35483871 0.266038327807423 0.6639 0.9773 1000013 Bio1_000137 CCCCC/C=C\C[C@H](O)\C=C\C=C\C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G06 compound treatment 1238840.0 180000.0 0.88 1324990.0 279000.0 1.66 1266910.0 219919.35483871 1.25958643810956 2.1927 0.9695 134 Bio1_000138 C/C(=C\c1ccc(cc1)C(=O)O)/c2ccc3c(c2)C(C)(C)CCC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G07 compound treatment 1143700.0 84400.0 0.41 1141780.0 96100.0 0.57 1052800.0 5809.35483871005 0.0332730358106585 0.5873 0.8324 1000014 Bio1_000139 CCCCC[C@H](O)/C=C/C=C/C=C/[C@@H](O)C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G08 compound treatment 1139040.0 79800.0 0.39 1181770.0 136000.0 0.81 1199230.0 152239.35483871 0.87194975104408 1.1957 0.9551 136 Bio1_000140 COC(C)(C)CCCC(C)C/C=C/C(=C/C(=O)O)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G09 compound treatment 1243810.0 185000.0 0.9 1250760.0 205000.0 1.22 1001970.0 -45020.64516129 -0.257855403957933 1.0758 0.6993 137 Bio1_000141 CCCCC/C=C\C/C=C\C/C=C\CC1OC1CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G10 compound treatment 1171160.0 112000.0 0.55 1360350.0 315000.0 1.87 1029170.0 -17820.64516129 -0.10206761010183 1.337 0.6849 138 Bio1_000142 Cc1cccc(Nc2cc(Cl)nc(SCC(=O)O)n2)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G11 compound treatment 1209360.0 150000.0 0.73 1179920.0 134000.0 0.8 1038050.0 -8940.64516128995 -0.0512074774017499 0.8547 0.7876 139 Bio1_000143 CCCCC/C=C\C/C=C\CC1OC1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G12 compound treatment 1272250.0 213000.0 1.04 1265390.0 220000.0 1.31 1027010.0 -19980.64516129 -0.11443899373158 1.289 0.7699 140 Bio1_000144 CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G13 compound treatment 1351450.0 292000.0 1.43 1317820.0 272000.0 1.62 1164510.0 117519.35483871 0.673091214180702 2.1471 0.9498 141 Bio1_000145 CCCCC/C=C\CC1OC1C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G14 compound treatment 1097440.0 38200.0 0.19 1046400.0 732.0 0.0 891550.0 -155440.64516129 -0.890285117104654 -0.4039 -0.444 142 Bio1_000146 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G15 compound treatment 1131870.0 72600.0 0.35 1084840.0 39200.0 0.23 979890.0 -67100.64516129 -0.384318436617592 0.1174 0.205 143 Bio1_000147 CCCCCC1OC1C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G16 compound treatment 1306530.0 247000.0 1.21 1105000.0 59300.0 0.35 1152000.0 105009.35483871 0.601440283991738 1.2484 0.895 144 Bio1_000148 CCCCCCCCC#CCC#CCC#CCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G17 compound treatment 1394800.0 336000.0 1.64 1180440.0 135000.0 0.8 959650.0 -87340.64516129 -0.50024288322228 1.1203 0.5921 145 Bio1_000149 CCCCC/C=C\C/C=C\C/C=C\C=C\C(=O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G18 compound treatment 1187620.0 128000.0 0.63 1104250.0 58600.0 0.35 923460.0 -123530.64516129 -0.707520833944793 0.1547 0.1535 146 Bio1_000150 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G19 compound treatment 1370880.0 312000.0 1.52 1236860.0 191000.0 1.14 1146930.0 99939.35483871 0.572401897416354 1.8659 0.9402 147 Bio1_000151 CCCCCC(=O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G20 compound treatment 1250980.0 192000.0 0.94 1352910.0 307000.0 1.83 1013930.0 -33060.64516129 -0.189354594600617 1.4863 0.7208 148 Bio1_000152 CCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G21 compound treatment 1317050.0 258000.0 1.26 1284160.0 238000.0 1.42 989660.0 -57330.64516129 -0.328360835662661 1.3563 0.7046 149 Bio1_000153 CCCCC(=O)/C=C/C=C\CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G22 compound treatment 591840.0 -467000.0 -2.28 559630.0 -486000.0 -2.89 483850.0 -563140.64516129 -3.22538377721983 -4.8494 -0.9905 150 Bio1_000154 CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G23 mock treatment 438120.0 -621000.0 -3.03 394080.0 -652000.0 -3.87 411250.0 -635740.64516129 -3.64119972699752 -6.0915 -0.995 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 G24 mock treatment 1092660.0 33400.0 0.16 1009840.0 -35800.0 -0.21 1180030.0 133039.35483871 0.761981896557419 0.4111 0.5089 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H01 compound treatment 968920.0 -90400.0 -0.44 951680.0 -94000.0 -0.56 1043520.0 -3470.64516128995 -0.0198780938578941 -0.5891 -0.8267 151 Bio1_000155 CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H02 compound treatment 653760.0 -406000.0 -1.98 630900.0 -415000.0 -2.47 626190.0 -420800.64516129 -2.41013250598904 -3.9594 -0.9955 2474 Bio1_000156 Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H03 compound treatment 890830.0 -168000.0 -0.82 807680.0 -238000.0 -1.42 816690.0 -230300.64516129 -1.31904519975421 -2.0538 -0.9769 152 Bio1_000157 Cn1c2ccccc2c3c4C(=O)NCc4c5c6ccccc6n(CCC#N)c5c13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H04 compound treatment 753160.0 -306000.0 -1.5 777440.0 -268000.0 -1.6 757940.0 -289050.64516129 -1.65553537949854 -2.7402 -0.9991 153 Bio1_000158 CC1=CC=C(CC1)N(CC2=NCCN2)c3cccc(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H05 compound treatment 468340.0 -591000.0 -2.89 438280.0 -607000.0 -3.61 435090.0 -611900.64516129 -3.50465630767658 -5.7757 -0.9954 154 Bio1_000159 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@@]32CC[C@]4(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H06 compound treatment 1021320.0 -38000.0 -0.19 1133760.0 88100.0 0.52 1179080.0 132089.35483871 0.756540778757298 0.6322 0.6734 3001155 Bio1_000160 CC1(C)NC(=O)NC1=O.c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H07 compound treatment 1206560.0 147000.0 0.72 1188110.0 142000.0 0.85 1292740.0 245749.35483871 1.40752756734864 1.7171 0.9575 155 Bio1_000161 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H08 compound treatment 110900.0 -948000.0 -4.63 90650.0 -955000.0 -5.68 80160.0 -966830.64516129 -5.53751519272608 -9.1511 -0.9962 156 Bio1_000162 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H09 compound treatment 1143470.0 84200.0 0.41 1126810.0 81100.0 0.48 1084400.0 37409.35483871 0.214261796319954 0.6398 0.9559 157 Bio1_000163 COC(=O)CC[C@H](NC(=O)CNC(=O)c1ccc(/C=C/C(=O)OC)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H10 compound treatment 1443730.0 384000.0 1.88 1379000.0 333000.0 1.98 1275750.0 228759.35483871 1.31021747111279 2.9853 0.9856 3104408 Bio1_000164 CC(N/C(=N\C#N)/Nc1ccncc1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H11 compound treatment 928220.0 -131000.0 -0.64 868360.0 -177000.0 -1.05 761150.0 -285840.64516129 -1.63715012882656 -1.9237 -0.9384 159 Bio1_000165 COc1c(C=O)c(O)cc2C(=O)c3ccccc3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H12 compound treatment 757610.0 -302000.0 -1.47 852020.0 -194000.0 -1.15 717390.0 -329600.64516129 -1.8877851971774 -2.6057 -0.9805 3104409 Bio1_000166 CCCNCC(O)COc1ccccc1.CC(=O)CCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H13 compound treatment 1256160.0 197000.0 0.96 1348450.0 303000.0 1.8 888320.0 -158670.64516129 -0.908784917625066 1.0702 0.4789 160 Bio1_000167 CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H14 compound treatment 1004770.0 -54500.0 -0.27 951790.0 -93900.0 -0.56 1136760.0 89769.35483871 0.514153299492951 -0.1792 -0.2228 161 Bio1_000168 COc1ccc2nccc(C(O)[C@H]3CC4CC[C@@H]3CC4C=C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H15 compound treatment 1104600.0 45300.0 0.22 1007360.0 -38300.0 -0.23 819860.0 -227130.64516129 -1.30088904877906 -0.7548 -0.5636 162 Bio1_000169 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H16 compound treatment 1360900.0 302000.0 1.47 1337630.0 292000.0 1.74 981510.0 -65480.64516129 -0.37503989889528 1.6367 0.7091 163 Bio1_000170 CCC(CC)(CC)CC(=O)Nc1c(C)cccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H17 compound treatment 1305820.0 247000.0 1.2 1189860.0 144000.0 0.86 947940.0 -99050.64516129 -0.567311819474301 0.863 0.5449 1001953 Bio1_000171 C/C=C/1\C2Cc3[nH]c(=O)ccc3C1(N)CC(=C2)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H18 compound treatment 195970.0 -863000.0 -4.22 166930.0 -879000.0 -5.23 120770.0 -926220.64516129 -5.30492172550195 -8.515 -0.995 165 Bio1_000172 OC(COc1cccc2[nH]c(C#N)cc12)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H19 compound treatment 91090.0 -968000.0 -4.73 69050.0 -977000.0 -5.81 39200.0 -1007790.64516129 -5.77211328229763 -9.4166 -0.9958 166 Bio1_000173 CC[C@@H](C)C[C@H](C)C[C@H](C)C(=O)/C=C(\O)/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]2CC[C@](C)(O2)[C@@H](C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H20 compound treatment 1074420.0 15100.0 0.07 1087700.0 42000.0 0.25 926950.0 -120040.64516129 -0.687531885394874 -0.2099 -0.2855 167 Bio1_000174 CC(C)OC(=O)C1=C(C)NC(=C([C@@H]1c2cccc3nonc23)[N+](=O)[O-])C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H21 compound treatment 242080.0 -817000.0 -3.99 228100.0 -818000.0 -4.86 201310.0 -845680.64516129 -4.8436294859001 -7.9086 -0.9961 3001166 Bio1_000175 C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(\C)/CC/C=C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H22 compound treatment 985230.0 -74100.0 -0.36 962120.0 -83500.0 -0.5 850000.0 -196990.64516129 -1.12826242720469 -1.1471 -0.8928 1000017 Bio1_000176 CC(C)OC(=O)C1=C(C)NC(=C([C@H]1c2cccc3nonc23)[N+](=O)[O-])C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H23 mock treatment 1146800.0 87500.0 0.43 1047300.0 1630.0 0.01 1043280.0 -3710.64516128995 -0.0212526920389773 0.2402 0.5609 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 H24 mock treatment 1128690.0 69400.0 0.34 1091140.0 45500.0 0.27 1024800.0 -22190.64516129 -0.127096751982388 0.2785 0.6163 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I01 compound treatment 1015040.0 -44200.0 -0.22 996870.0 -48800.0 -0.29 991370.0 -55620.64516129 -0.318566823622443 -0.4763 -0.9879 170 Bio1_000177 CCCCCCCC[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I02 compound treatment 1058480.0 -801.0 0.0 1041280.0 -4390.0 -0.03 956960.0 -90030.64516129 -0.515649837835255 -0.315 -0.6101 171 Bio1_000178 CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC/C=C\CCCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I03 compound treatment 1093140.0 33900.0 0.17 1027170.0 -18500.0 -0.11 981920.0 -65070.64516129 -0.372691627002596 -0.1832 -0.4337 1000018 Bio1_000179 CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I04 compound treatment 248530.0 -811000.0 -3.96 249500.0 -796000.0 -4.73 208500.0 -838490.64516129 -4.80244881539181 -7.7931 -0.9964 173 Bio1_000180 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](CO)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I05 compound treatment 954330.0 -105000.0 -0.51 1005760.0 -39900.0 -0.24 933660.0 -113330.64516129 -0.649100411248754 -0.8078 -0.9387 174 Bio1_000181 OCCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I06 compound treatment 1128320.0 69000.0 0.34 1190110.0 144000.0 0.86 1023210.0 -23780.64516129 -0.136203464932065 0.612 0.6561 175 Bio1_000182 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I07 compound treatment 1352860.0 294000.0 1.43 1263130.0 217000.0 1.29 1102360.0 55369.35483871 0.317127560204351 1.7578 0.8982 176 Bio1_000183 O[C@@H](CCCC(=O)O)/C=C\C=C\C=C\[C@H](O)C/C=C\CCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I08 compound treatment 1152420.0 93100.0 0.46 1083790.0 38100.0 0.23 1049240.0 2249.35483871005 0.0128831627912569 0.4011 0.7886 177 Bio1_000184 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I09 compound treatment 1238900.0 180000.0 0.88 1128890.0 83200.0 0.49 1011110.0 -35880.64516129 -0.205506123228345 0.6737 0.6552 178 Bio1_000185 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I10 compound treatment 1067060.0 7780.0 0.04 1099840.0 54200.0 0.32 1024190.0 -22800.64516129 -0.130590522359308 0.1325 0.379 179 Bio1_000186 CCCCCCCCCCCCCCCCOC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I11 compound treatment 1157760.0 98500.0 0.48 1106400.0 60700.0 0.36 983960.0 -63030.64516129 -0.361007542463389 0.2779 0.3961 180 Bio1_000187 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(N)C(=O)NCC(=O)O)[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I12 compound treatment 1121060.0 61800.0 0.3 1061690.0 16000.0 0.1 942280.0 -104710.64516129 -0.599729426578181 -0.117 -0.1725 181 Bio1_000188 CCCCCCCCCCCCCCCCOCC(CO)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I13 compound treatment 1189290.0 130000.0 0.64 1184730.0 139000.0 0.83 1209950.0 162959.35483871 0.933348469799132 1.383 0.9883 182 Bio1_000189 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(N)C(=O)O)[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I14 compound treatment 1054180.0 -5100.0 -0.02 1103360.0 57700.0 0.34 958040.0 -88950.64516129 -0.50946414602038 -0.1105 -0.1797 183 Bio1_000190 CCCCCCCCCCCCCCCCOCC(CO)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I15 compound treatment 1153760.0 94500.0 0.46 1001440.0 -44200.0 -0.26 932730.0 -114260.64516129 -0.654426979200452 -0.2632 -0.3122 184 Bio1_000191 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(NC(=O)C)C(=O)O)[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I16 compound treatment 1140540.0 81300.0 0.4 1099690.0 54000.0 0.32 1033500.0 -13490.64516129 -0.07726756791812 0.3701 0.7165 185 Bio1_000192 CCCCC[C@H](O)/C=C/[C@H]1OC(O)C[C@H](O)[C@@H]1C/C=C\CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I17 compound treatment 1102000.0 42700.0 0.21 1150820.0 105000.0 0.63 909970.0 -137020.64516129 -0.784784706706514 0.0284 0.0277 186 Bio1_000193 CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I18 compound treatment 1323320.0 264000.0 1.29 1178130.0 132000.0 0.79 1001300.0 -45690.64516129 -0.261692823880123 1.0485 0.6835 187 Bio1_000194 CCCCCC#CC[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I19 compound treatment 1119200.0 59900.0 0.29 1174020.0 128000.0 0.76 944270.0 -102720.64516129 -0.588331716660032 0.27 0.2681 188 Bio1_000195 CCCCC[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I20 compound treatment 1248110.0 189000.0 0.92 1136260.0 90600.0 0.54 1139680.0 92689.35483871 0.530877577362797 1.1502 0.9641 189 Bio1_000196 CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I21 compound treatment 1176640.0 117000.0 0.57 1043840.0 -1830.0 -0.01 953310.0 -93680.64516129 -0.536555185172563 0.015 0.0191 190 Bio1_000197 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I22 compound treatment 1248680.0 189000.0 0.93 1261380.0 216000.0 1.28 1186500.0 139509.35483871 0.799038772522456 1.7362 0.9798 191 Bio1_000198 CCCc1c(O)c(ccc1OCCCCc2nnn[nH]2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I23 mock treatment 1061630.0 2350.0 0.01 1016010.0 -29700.0 -0.18 1247640.0 200649.35483871 1.14921765915341 0.5683 0.4888 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 I24 mock treatment 1094720.0 35400.0 0.17 1042790.0 -2880.0 -0.02 1067270.0 20279.35483871 0.116149851145136 0.1571 0.7512 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J01 compound treatment 648640.0 -411000.0 -2.01 761130.0 -285000.0 -1.69 802080.0 -244910.64516129 -1.40272386402765 -2.9451 -0.9897 192 Bio1_000199 CCCCC(C)/C=C(\C)/C=C(\C)/C(=O)NC1=CC(O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)C3OC3C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J02 compound treatment 732270.0 -327000.0 -1.6 646030.0 -400000.0 -2.38 720290.0 -326700.64516129 -1.87117546915598 -3.3748 -0.9866 193 Bio1_000200 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J03 compound treatment 800640.0 -259000.0 -1.26 684160.0 -362000.0 -2.15 766980.0 -280010.64516129 -1.60375884801108 -2.8967 -0.977 275745 Bio1_000201 Cc1ccc(cc1)c2nn(c3ncnc(N)c23)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J04 compound treatment 63610.0 -996000.0 -4.86 62720.0 -983000.0 -5.85 54240.0 -992750.64516129 -5.68597179628307 -9.4661 -0.9969 194 Bio1_000202 CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J05 compound treatment 424860.0 -634000.0 -3.1 307460.0 -738000.0 -4.39 400040.0 -646950.64516129 -3.70540491703895 -6.4634 -0.9902 195 Bio1_000203 CC(=O)OCOC(c1cc(Oc2ccc(Br)cc2)ccc1[N+](=O)[O-])P(=O)(OCOC(=O)C)OCOC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J06 compound treatment 1218180.0 159000.0 0.78 1095630.0 50000.0 0.3 1128030.0 81039.35483871 0.464152290656047 0.8877 0.9324 196 Bio1_000204 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J07 compound treatment 966410.0 -92900.0 -0.45 1026560.0 -19100.0 -0.11 846360.0 -200630.64516129 -1.14911049961779 -0.991 -0.7988 197 Bio1_000205 O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J08 compound treatment 1188590.0 129000.0 0.63 1051790.0 6120.0 0.04 1077560.0 30569.35483871 0.175085748159081 0.4869 0.7415 198 Bio1_000206 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J09 compound treatment 319650.0 -740000.0 -3.61 260820.0 -785000.0 -4.67 245190.0 -801800.64516129 -4.59230711845871 -7.4323 -0.9938 199 Bio1_000207 C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)c1ccc(cc1)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J10 compound treatment 996200.0 -63100.0 -0.31 954830.0 -90800.0 -0.54 953440.0 -93550.64516129 -0.535810611157809 -0.7992 -0.9735 200 Bio1_000208 COc1ccc(cc1OC)C(=O)OC2CC[C@@]3(C)C4CCC5[C@@]3(C[C@@]6(O)C7CN8CC(C)CCC8[C@@](C)(O)[C@@]7(O)[C@@H](O)C[C@@]56O)O[C@@]42O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J11 compound treatment 1214240.0 155000.0 0.76 1110190.0 64500.0 0.38 1065990.0 18999.35483871 0.108818660846026 0.7215 0.8431 201 Bio1_000209 COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)CF 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J12 compound treatment 951590.0 -108000.0 -0.53 930620.0 -115000.0 -0.68 853800.0 -193190.64516129 -1.10649795600421 -1.3376 -0.9532 202 Bio1_000210 COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J13 compound treatment 746450.0 -313000.0 -1.53 749960.0 -296000.0 -1.76 752570.0 -294420.64516129 -1.68629201380028 -2.8713 -0.9983 203 Bio1_000211 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J14 compound treatment 1151100.0 91800.0 0.45 1010880.0 -34800.0 -0.21 877250.0 -169740.64516129 -0.972188258727531 -0.4217 -0.3867 3104544 Bio1_000212 CC(O)(C(=O)Nc1ccccc1)C(F)(F)F.CS(=O)(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J15 compound treatment 76990.0 -982000.0 -4.8 57920.0 -988000.0 -5.87 44800.0 -1002190.64516129 -5.74003932473902 -9.4761 -0.9962 1000019 Bio1_000213 CO[C@@]12[C@H]3N[C@H]3CN2C4=C([C@H]1COC(=O)N)C(=O)C(=C(C)C4=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J16 compound treatment 348640.0 -711000.0 -3.47 344160.0 -702000.0 -4.17 306470.0 -740520.64516129 -4.24132638288878 -6.8618 -0.9962 3104545 Bio1_000214 CC1CC(C)/C=C(/C)\CC(C)C(=O)NC(C)C(=O)N(C)C(Cc2c(Br)[nH]c3ccccc23)C(=O)NC(CC(=O)O1)c4ccc(O)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J17 compound treatment 994160.0 -65100.0 -0.32 945710.0 -100000.0 -0.59 951910.0 -95080.64516129 -0.544573674562215 -0.8413 -0.9707 47 Bio1_000215 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J18 compound treatment 78830.0 -980000.0 -4.79 60800.0 -985000.0 -5.86 44110.0 -1002880.64516129 -5.74399129450963 -9.4633 -0.9962 207 Bio1_000216 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)/C=C/S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J19 compound treatment 370770.0 -689000.0 -3.36 342310.0 -703000.0 -4.18 315260.0 -731730.64516129 -4.19098172450661 -6.7766 -0.9951 208 Bio1_000217 CC(C)(C)c1cc(/C=C(\C#N)/C(=S)N)cc(c1O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J20 compound treatment 170400.0 -889000.0 -4.34 150960.0 -895000.0 -5.32 130330.0 -916660.64516129 -5.25016689795547 -8.6103 -0.996 209 Bio1_000218 CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(=O)N)C(=O)N5CC(O)CC5C(=O)NC(C(C)C(O)CO)C(=O)N2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J21 compound treatment 560280.0 -499000.0 -2.44 458400.0 -587000.0 -3.49 254900.0 -792090.64516129 -4.53669316704905 -6.0431 -0.9711 2413 Bio1_000219 CC(C)CC(NC(=O)CNC(=O)C(C)(C)NC(=O)C(NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C1CCCN1C(=O)C(C)(C)NC(=O)C)C(C)C)C(=O)NC(C)(C)C(=O)N2CCCC2C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CO)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J22 compound treatment 705790.0 -353000.0 -1.73 637840.0 -408000.0 -2.43 572430.0 -474560.64516129 -2.71804249855169 -3.9666 -0.9839 1000021 Bio1_000220 CC(C)N(C)c1nc(N)c(nc1Cl)C(=O)NC(=N)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J23 mock treatment 1209080.0 150000.0 0.73 1122450.0 76800.0 0.46 1032860.0 -14130.64516129 -0.0809331630676753 0.6394 0.738 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 J24 mock treatment 1136080.0 76800.0 0.38 1092160.0 46500.0 0.28 1211520.0 164529.35483871 0.942340632900385 0.9203 0.8754 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K01 compound treatment 1051420.0 -7860.0 -0.04 1106400.0 60700.0 0.36 1032250.0 -14740.64516129 -0.0844269334445953 0.1376 0.369 212 Bio1_000221 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K02 compound treatment 1001870.0 -57400.0 -0.28 992960.0 -52700.0 -0.31 861880.0 -185110.64516129 -1.06021981724107 -0.955 -0.8373 213 Bio1_000222 CCCCC/C=C\CC(O)/C=C/c1cccc(CC(O)CCCCC)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K03 compound treatment 985920.0 -73400.0 -0.36 977560.0 -68100.0 -0.41 1061540.0 14549.35483871 0.0833313195717737 -0.3927 -0.7176 214 Bio1_000223 CCCCC[C@H](O)/C=C/C1=C(CCCCCCC(=O)O)C(=O)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K04 compound treatment 1025300.0 -34000.0 -0.17 1018170.0 -27500.0 -0.16 1085770.0 38779.35483871 0.222108460936971 -0.062 -0.1927 215 Bio1_000224 CCCC/C=C\CC1C(CNNC(=O)Nc2ccccc2)C3CCC1O3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K05 compound treatment 1007720.0 -51600.0 -0.25 1039330.0 -6340.0 -0.04 1118720.0 71729.35483871 0.410829336214859 0.07 0.1448 216 Bio1_000225 CCCCC[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K06 compound treatment 1113600.0 54300.0 0.27 1142560.0 96900.0 0.58 1056430.0 9439.35483871005 0.0540638332995427 0.5171 0.8122 217 Bio1_000226 O[C@@H](COc1cccc(c1)C(F)(F)F)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K07 compound treatment 1161310.0 102000.0 0.5 1158620.0 113000.0 0.67 1087090.0 40099.35483871 0.229668750932929 0.8082 0.9317 218 Bio1_000227 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K08 compound treatment 1095040.0 35800.0 0.17 1075330.0 29700.0 0.18 1032570.0 -14420.64516129 -0.0825941358698176 0.155 0.5925 219 Bio1_000228 O[C@@H](COc1cccc(Cl)c1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K09 compound treatment 1075860.0 16600.0 0.08 1039460.0 -6210.0 -0.04 1014640.0 -32350.64516129 -0.185288074981579 -0.0815 -0.3966 220 Bio1_000229 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K10 compound treatment 1103810.0 44500.0 0.22 1040000.0 -5670.0 -0.03 1066880.0 19889.35483871 0.113916129100876 0.1719 0.6936 221 Bio1_000230 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K11 compound treatment 1226720.0 167000.0 0.82 1131580.0 85900.0 0.51 1079540.0 32549.35483871 0.186426183153018 0.8749 0.8906 222 Bio1_000231 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K12 compound treatment 990930.0 -68400.0 -0.33 1044990.0 -678.0 0.0 1047000.0 9.35483871004544 5.35797678131487E-5 -0.1951 -0.5842 223 Bio1_000232 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K13 compound treatment 633680.0 -426000.0 -2.08 597980.0 -448000.0 -2.66 591840.0 -455150.64516129 -2.60687187065658 -4.2427 -0.9943 224 Bio1_000233 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K14 compound treatment 1122850.0 63600.0 0.31 1035210.0 -10500.0 -0.06 1068020.0 21029.35483871 0.120445470461022 0.213 0.6284 225 Bio1_000234 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K15 compound treatment 1001860.0 -57400.0 -0.28 1063680.0 18000.0 0.11 1101070.0 54079.35483871 0.309739094981028 0.0787 0.1824 226 Bio1_000235 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K16 compound treatment 1066010.0 6730.0 0.03 1055110.0 9440.0 0.06 1105610.0 58619.35483871 0.335741910573187 0.2452 0.7171 227 Bio1_000236 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K17 compound treatment 1178010.0 119000.0 0.58 1125290.0 79600.0 0.47 1160380.0 113389.35483871 0.649436670481228 0.9832 0.992 228 Bio1_000237 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2O\C(=C\CCCCC(=O)O)\C[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K18 compound treatment 1065400.0 6120.0 0.03 1096190.0 50500.0 0.3 1279080.0 232089.35483871 1.32929002087532 0.9582 0.7029 229 Bio1_000238 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K19 compound treatment 1266210.0 207000.0 1.01 1068600.0 22900.0 0.14 1254820.0 207829.35483871 1.19034105473749 1.3497 0.8609 230 Bio1_000239 CCCCCC(=O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K20 compound treatment 1154110.0 94800.0 0.46 1103850.0 58200.0 0.35 1030610.0 -16380.64516129 -0.0938200210153309 0.4131 0.7052 231 Bio1_000240 CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K21 compound treatment 1257440.0 198000.0 0.97 1073760.0 28100.0 0.17 1108030.0 61039.35483871 0.349602442232443 0.8573 0.8221 232 Bio1_000241 CCCCCC(=O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K22 compound treatment 1243940.0 185000.0 0.9 975800.0 -69900.0 -0.42 1030430.0 -16560.64516129 -0.0948509696511433 0.2263 0.2268 233 Bio1_000242 CCCCCCCCCCC/C=C\C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K23 mock treatment 1129920.0 70600.0 0.35 1019410.0 -26300.0 -0.16 1053440.0 6449.35483871005 0.0369386309602138 0.1304 0.3427 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 K24 mock treatment 1056560.0 -2720.0 -0.01 988340.0 -57300.0 -0.34 960380.0 -86610.64516129 -0.496061813754819 -0.4909 -0.8154 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L01 compound treatment 271100.0 -788000.0 -3.85 252960.0 -793000.0 -4.71 260320.0 -786670.64516129 -4.50565015812625 -7.5462 -0.9965 1000022 Bio1_000243 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)C42OC(=O)/C=C/[C@@H](O)CCC[C@@H](C)C\C=C/[C@H]4[C@H](O)C1=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L02 compound treatment 785290.0 -274000.0 -1.34 735460.0 -310000.0 -1.84 749280.0 -297710.64516129 -1.70513546386597 -2.8224 -0.9915 1000023 Bio1_000244 NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L03 compound treatment 761180.0 -298000.0 -1.46 705620.0 -340000.0 -2.02 755170.0 -291820.64516129 -1.67140053350521 -2.9733 -0.9909 236 Bio1_000245 SC(=S)OC1CC2CC1C3CCCC23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L04 compound treatment 1002240.0 -57000.0 -0.28 1006260.0 -39400.0 -0.23 1172000.0 125009.35483871 0.715990132415342 0.1172 0.1459 1000024 Bio1_000246 NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(=O)NC(Cc5ccccc5)C(=O)NC(CCCNC(=N)N)C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L05 compound treatment 100970.0 -958000.0 -4.68 73300.0 -972000.0 -5.78 67630.0 -979360.64516129 -5.60928067276347 -9.2801 -0.996 3584 Bio1_000247 COc1cccc2C(=O)C3C(C(=C4[C@H](C[C@@](O)(CC4=C3O)C(=O)CO)O[C@@H]5CC(N)[C@H](O)C(C)O5)O)C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L06 compound treatment 1431230.0 372000.0 1.82 1400250.0 355000.0 2.11 1408160.0 361169.35483871 2.06859474260127 3.4609 0.9979 677 Bio1_000248 C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L07 compound treatment 747140.0 -312000.0 -1.53 658080.0 -388000.0 -2.3 542000.0 -504990.64516129 -2.8923300929282 -3.8811 -0.9702 239 Bio1_000249 CC(=O)OCOC(c1ccc2ccccc2c1)P(=O)(OCOC(=O)C)OCOC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L08 compound treatment 1217920.0 159000.0 0.78 1182350.0 137000.0 0.81 1308420.0 261429.35483871 1.49733464851275 1.7812 0.9517 240 Bio1_000250 C1CNCCC(C1)Sc2cccc3cnccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L09 compound treatment 675260.0 -384000.0 -1.88 680870.0 -365000.0 -2.17 722140.0 -324850.64516129 -1.8605796081768 -3.4099 -0.9974 241 Bio1_000251 CC[C@@H](C)[C@@H](CO[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)OC(C)C)NCC(N)CS 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L10 compound treatment 299250.0 -760000.0 -3.71 326120.0 -720000.0 -4.28 297530.0 -749460.64516129 -4.29253016513414 -7.0926 -0.9978 242 Bio1_000252 CC/C(=C\C(C)C\C=C\C(=C\C(=C\C(C)C(=O)C(C)C(O)C(C)C/C=C/C(=O)O)\C)\C)/C=C/C1OC(=O)C=CC1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L11 compound treatment 61020.0 -998000.0 -4.88 48390.0 -997000.0 -5.93 35880.0 -1011110.64516129 -5.79112855713594 -9.5833 -0.9965 243 Bio1_000253 O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L12 compound treatment 799320.0 -260000.0 -1.27 846290.0 -199000.0 -1.19 848760.0 -198230.64516129 -1.13536451780696 -2.0733 -0.9989 244 Bio1_000254 CC[N+](C)(CC)CCC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L13 compound treatment 538250.0 -521000.0 -2.55 589030.0 -457000.0 -2.72 512220.0 -534770.64516129 -3.06289481723095 -4.8059 -0.997 3104621 Bio1_000255 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L14 compound treatment 1326690.0 267000.0 1.31 1375270.0 330000.0 1.96 1369890.0 322899.35483871 1.8494036076427 2.9537 0.9863 1000025 Bio1_000256 CS(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L15 compound treatment 959600.0 -99700.0 -0.49 1065490.0 19800.0 0.12 996570.0 -50420.64516129 -0.288783863032306 -0.3799 -0.6568 247 Bio1_000257 Nc1ncnc2n([C@H]3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)c(Br)nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L16 compound treatment 98990.0 -960000.0 -4.69 80580.0 -965000.0 -5.74 60720.0 -986270.64516129 -5.64885764539383 -9.2836 -0.9961 1000026 Bio1_000258 C[C@@H](C[C@H](O)C1OC2CC[C@]3(CC[C@@H](O3)/C=C/[C@@H](C)[C@H]4CC(=CC5(OC(C[C@@](C)(O)C(=O)O)CC[C@H]5O)O4)C)OC2[C@H](O)C1=C)[C@H]6O[C@@]7(CCCCO7)CC[C@H]6C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L17 compound treatment 1233010.0 174000.0 0.85 1147080.0 101000.0 0.6 991870.0 -55120.64516129 -0.315703077411853 0.656 0.6029 249 Bio1_000259 O[C@@H]1[C@H](O[C@H]2COP(=O)(O)O[C@H]12)n3c(Br)nc4C(=O)=NC(=Nc43)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L18 compound treatment 137150.0 -922000.0 -4.51 121470.0 -924000.0 -5.5 80990.0 -966000.64516129 -5.5327613740165 -8.9685 -0.9958 250 Bio1_000260 COC[C@@H]([C@H](O)[C@H](O)C(=O)NCC[C@H](C)c1nc(/C=C/C[C@@H]2O[C@]3(C[C@@H](O)[C@@H]2C)O[C@H]([C@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C(\C)/C(=C/C=C/C(=C\C#N)/C)/C)OC)[C@H](OP(=O)(O)O)C3(C)C)co1)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L19 compound treatment 1298520.0 239000.0 1.17 1117140.0 71500.0 0.43 1294310.0 247319.35483871 1.4165197304499 1.7381 0.922 251 Bio1_000261 Nc1ncnc2n(cnc12)C3(CO)OC(=C)C(O)C3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L20 compound treatment 1167860.0 109000.0 0.53 1063900.0 18200.0 0.11 1303570.0 256579.35483871 1.46955631027003 1.2173 0.7773 252 Bio1_000262 CCCCCCOC(=O)[C@]1(O)C[C@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L21 compound treatment 1206630.0 147000.0 0.72 1126360.0 80700.0 0.48 1056010.0 9019.35483871005 0.051658286482647 0.7225 0.8336 253 Bio1_000263 CCCC(=O)NC1=NC2C(N=CN2[C@@H]3O[C@H]4OP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC)C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L22 compound treatment 223410.0 -836000.0 -4.08 229300.0 -816000.0 -4.85 162810.0 -884180.64516129 -5.06413794411554 -8.0844 -0.9959 254 Bio1_000264 CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L23 mock treatment 1014290.0 -45000.0 -0.22 970720.0 -74900.0 -0.45 1035610.0 -11380.64516129 -0.0651825589094297 -0.4219 -0.8417 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 L24 mock treatment 1055560.0 -3720.0 -0.02 1000400.0 -45300.0 -0.27 995410.0 -51580.64516129 -0.295427754240875 -0.3365 -0.841 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M01 compound treatment 1025130.0 -34200.0 -0.17 973700.0 -72000.0 -0.43 968160.0 -78830.64516129 -0.451501922718036 -0.6041 -0.9379 255 Bio1_000265 CCCCCC(=O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M02 compound treatment 1024080.0 -35200.0 -0.17 965990.0 -79700.0 -0.47 1016530.0 -30460.64516129 -0.174463114305549 -0.4736 -0.8879 256 Bio1_000266 CCCCC/C=C\C/C=C\CCCCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M03 compound treatment 927450.0 -132000.0 -0.64 966670.0 -79000.0 -0.47 989050.0 -57940.64516129 -0.331854606039581 -0.8347 -0.9666 257 Bio1_000267 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M04 compound treatment 989640.0 -69600.0 -0.34 977280.0 -68400.0 -0.41 1036570.0 -10420.64516129 -0.0596841661850967 -0.4657 -0.8728 258 Bio1_000268 CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M05 compound treatment 1013120.0 -46200.0 -0.23 1049330.0 3660.0 0.02 1255880.0 208889.35483871 1.19641219670394 0.5731 0.4707 259 Bio1_000269 CCCCC(C)(C)[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M06 compound treatment 987570.0 -71700.0 -0.35 1033950.0 -11700.0 -0.07 1212170.0 165179.35483871 0.946063502974152 0.3037 0.3003 260 Bio1_000270 CC/C=C\C/C=C\C/C=C\CCCCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M07 compound treatment 1008410.0 -50900.0 -0.25 1071870.0 26200.0 0.16 1094100.0 47109.35483871 0.269818472805402 0.1022 0.2565 261 Bio1_000271 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@H]2CO[C@@H]1C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M08 compound treatment 1060210.0 929.0 0.0 1043680.0 -1990.0 -0.01 1196530.0 149539.35483871 0.856485521506893 0.4903 0.5724 262 Bio1_000272 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M09 compound treatment 1053630.0 -5650.0 -0.03 1060000.0 14300.0 0.09 1302470.0 255479.35483871 1.46325606860673 0.8781 0.599 1000027 Bio1_000273 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H](O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M10 compound treatment 1003620.0 -55700.0 -0.27 996770.0 -48900.0 -0.29 1284410.0 237419.35483871 1.35981755548021 0.4602 0.3248 264 Bio1_000274 CC/C=C\C/C=C\C/C=C\CCCCCCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M11 compound treatment 1001210.0 -58100.0 -0.28 1017710.0 -28000.0 -0.17 1242270.0 195279.35483871 1.11846102485168 0.3859 0.3311 1000028 Bio1_000275 CCCCC[C@H](O)/C=C/[C@H]1[C@@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M12 compound treatment 1137480.0 78200.0 0.38 1235840.0 190000.0 1.13 1042990.0 -4000.64516128995 -0.0229136648411196 0.8603 0.7206 266 Bio1_000276 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M13 compound treatment 1060750.0 1470.0 0.01 985710.0 -60000.0 -0.36 1164360.0 117369.35483871 0.672232090317525 0.1864 0.245 267 Bio1_000277 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M14 compound treatment 1160400.0 101000.0 0.49 1046640.0 972.0 0.01 1266560.0 219569.35483871 1.25758181576215 1.0146 0.7509 268 Bio1_000278 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M15 compound treatment 1035900.0 -23400.0 -0.11 988020.0 -57600.0 -0.34 967740.0 -79250.64516129 -0.453907469534932 -0.5259 -0.9065 269 Bio1_000279 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M16 compound treatment 1075040.0 15800.0 0.08 1110080.0 64400.0 0.38 1254880.0 207889.35483871 1.19068470428276 0.953 0.7605 270 Bio1_000280 CCCCC/C=C\C/C=C\CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M17 compound treatment 1010360.0 -48900.0 -0.24 997140.0 -48500.0 -0.29 1228370.0 181379.35483871 1.03884888019727 0.2952 0.2673 271 Bio1_000281 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2C/C(=C\CCCC(=O)O)/C[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M18 compound treatment 1045570.0 -13700.0 -0.07 987490.0 -58200.0 -0.35 1060650.0 13659.35483871 0.0782338513169233 -0.1932 -0.5354 272 Bio1_000282 OC(=O)CCCCCCCCCCCCCCCC#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M19 compound treatment 1248850.0 190000.0 0.93 1007520.0 -38100.0 -0.23 1039200.0 -7790.64516128995 -0.0446208611173927 0.378 0.396 273 Bio1_000283 CCCCCCCN[C@H]1CCC[C@@H]1CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M20 compound treatment 93550.0 -966000.0 -4.72 65070.0 -981000.0 -5.83 60410.0 -986580.64516129 -5.65063316804439 -9.3532 -0.9959 274 Bio1_000284 CCCCCCCCCCCCC(O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M21 compound treatment 1110780.0 51500.0 0.25 1019290.0 -26400.0 -0.16 1282880.0 235889.35483871 1.35105449207581 0.8347 0.6035 275 Bio1_000285 C[C@@H](O)CCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M22 compound treatment 1106940.0 47700.0 0.23 990930.0 -54700.0 -0.33 1139540.0 92549.35483871 0.530075728423832 0.2525 0.3802 276 Bio1_000286 CCCCCCCCCCCCCCC(F)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M23 mock treatment 1036810.0 -22500.0 -0.11 1016000.0 -29700.0 -0.18 1078720.0 31729.35483871 0.18172963936765 -0.0603 -0.2185 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 M24 mock treatment 941340.0 -118000.0 -0.58 983640.0 -62000.0 -0.37 1039370.0 -7620.64516128995 -0.043647187405792 -0.5708 -0.8327 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N01 compound treatment 330150.0 -729000.0 -3.56 312980.0 -733000.0 -4.36 341680.0 -705310.64516129 -4.03966137473903 -6.9046 -0.9967 3000146 Bio1_000287 OC[C@H]1O[C@H](C(O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N02 compound treatment 531070.0 -528000.0 -2.58 574560.0 -471000.0 -2.8 557620.0 -489370.64516129 -2.80286666130937 -4.7257 -0.9993 1000029 Bio1_000288 CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]cn1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCC(=O)N4)C(C)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N03 compound treatment 144190.0 -915000.0 -4.47 212960.0 -833000.0 -4.95 262080.0 -784910.64516129 -4.49556977146498 -8.0357 -0.9989 279 Bio1_000289 COc1cc2CCN(C)[C@@H]3Cc4ccc(OC(=O)c5ccc(cc5)[N+](=O)[O-])c(Oc6ccc(C[C@@H]7N(C)CCc8cc(OC)c(Oc(c1OC)c32)cc78)cc6)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N04 compound treatment 422720.0 -637000.0 -3.11 399120.0 -647000.0 -3.84 412690.0 -634300.64516129 -3.63295213791102 -6.1129 -0.9962 3104694 Bio1_000290 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)C42OC(=O)/C=C/[C@H](O)CCC[C@@H](C)C\C=C\[C@H]4[C@H](O)C1=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N05 compound treatment 495200.0 -564000.0 -2.76 502020.0 -544000.0 -3.23 567810.0 -479180.64516129 -2.74450351353754 -5.0422 -0.997 281 Bio1_000291 Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N06 compound treatment 1038290.0 -21000.0 -0.1 1019460.0 -26200.0 -0.16 1131650.0 84659.35483871 0.48488581322072 0.1308 0.2517 282 Bio1_000292 CN([C@@H](Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C(=O)N4CCN(CC4)c5ccccc5)S(=O)(=O)c6cccc7cnccc67 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N07 compound treatment 797800.0 -261000.0 -1.28 748170.0 -297000.0 -1.77 802470.0 -244520.64516129 -1.40049014198339 -2.5676 -0.9902 3104696 Bio1_000293 CO[C@@H]1CC(CC(C)[C@@H]2CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)/C=C/C=C/C=C(\C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N08 compound treatment 855900.0 -203000.0 -0.99 836960.0 -209000.0 -1.24 785170.0 -261820.64516129 -1.49957576086981 -2.156 -0.9865 284 Bio1_000294 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3cc(O)ccc3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N09 compound treatment 965240.0 -94000.0 -0.46 905410.0 -140000.0 -0.83 990930.0 -56060.64516129 -0.321086920287762 -0.9322 -0.9276 285 Bio1_000295 O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N10 compound treatment 521810.0 -537000.0 -2.63 368240.0 -677000.0 -4.03 484480.0 -562510.64516129 -3.22177545699449 -5.702 -0.9851 907409 Bio1_000296 CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N11 compound treatment 81140.0 -978000.0 -4.78 67570.0 -978000.0 -5.82 61000.0 -985990.64516129 -5.6472539475159 -9.3777 -0.9965 1000031 Bio1_000297 CC(C)CCCCCCCC/C=C/C(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](C[C@@H](O)[C@H]2O[C@H]([C@H](O)[C@@H]2O)n3ccc(=O)[nH]c3=O)O[C@H]1O[C@@H]4O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]4NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N12 compound treatment 1045000.0 -14300.0 -0.07 1059330.0 13700.0 0.08 1076670.0 29679.35483871 0.169988279904231 0.1048 0.5214 288 Bio1_000298 C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N13 compound treatment 257380.0 -802000.0 -3.92 241180.0 -804000.0 -4.78 224670.0 -822320.64516129 -4.70983526294133 -7.7433 -0.9962 289 Bio1_000299 CCCNC(=O)C1OC1C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N14 compound treatment 222830.0 -836000.0 -4.09 398730.0 -647000.0 -3.85 460610.0 -586380.64516129 -3.35849070108806 -6.5196 -0.9968 290 Bio1_000300 CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)C)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N15 compound treatment 707760.0 -352000.0 -1.72 767690.0 -278000.0 -1.65 679590.0 -367400.64516129 -2.10428441069802 -3.1609 -0.9941 607 Bio1_000301 Brc1ccc(/C=C/CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N16 compound treatment 459960.0 -599000.0 -2.93 465960.0 -580000.0 -3.45 465020.0 -581970.64516129 -3.33323245951066 -5.6053 -0.9976 291 Bio1_000302 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N17 compound treatment 106570.0 -953000.0 -4.65 100320.0 -945000.0 -5.62 95560.0 -951430.64516129 -5.44931180943991 -9.0792 -0.9968 292 Bio1_000303 O=C1NCc2c1c3c4ccccc4[nH]c3c5[nH]c6ccccc6c25 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N18 compound treatment 457830.0 -601000.0 -2.94 437360.0 -608000.0 -3.62 475880.0 -571110.64516129 -3.27103189181664 -5.6736 -0.9964 293 Bio1_000304 COC[C@H]1OC(=O)c2coc3C(=O)C4=C([C@@H](C[C@@]5(C)C4CCC5=O)OC(=O)C)[C@]1(C)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N19 compound treatment 1364430.0 305000.0 1.49 1409810.0 364000.0 2.17 1310980.0 263989.35483871 1.51199702911097 2.9839 0.9839 294 Bio1_000305 [O-][N+](=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N20 compound treatment 165880.0 -893000.0 -4.36 130400.0 -915000.0 -5.44 127800.0 -919190.64516129 -5.26465745378106 -8.702 -0.9956 3104702 Bio1_000306 C[C@H]1CCC/C=C/C2C[C@H](O)C[C@H]2[C@H](O)/C=C/C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N21 compound treatment 1117310.0 58000.0 0.28 1129410.0 83700.0 0.5 1175840.0 128849.35483871 0.737983703312674 0.8773 0.9389 3000152 Bio1_000307 Nc1ncnc2[n+](c[nH]c12)C3CCCO3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N22 compound treatment 85080.0 -974000.0 -4.76 59170.0 -986000.0 -5.87 56380.0 -990610.64516129 -5.67371496250175 -9.4107 -0.9961 297 Bio1_000308 COc1ccc2c(cc(N)c3c2ccc4cc5OCOc5cc43)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N23 mock treatment 1093760.0 34500.0 0.17 1048730.0 3060.0 0.02 1187310.0 140319.35483871 0.803678041383612 0.5718 0.6961 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 N24 mock treatment 963960.0 -95300.0 -0.47 1053540.0 7870.0 0.05 1021530.0 -25460.64516129 -0.145825652199647 -0.326 -0.6651 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O01 compound treatment 822300.0 -237000.0 -1.16 840680.0 -205000.0 -1.22 886630.0 -160360.64516129 -0.918464379816861 -1.9025 -0.9931 298 Bio1_000309 C[C@@H](O)CCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O02 compound treatment 1044270.0 -15000.0 -0.07 1017200.0 -28500.0 -0.17 1199880.0 152889.35483871 0.875672621117847 0.3655 0.4084 299 Bio1_000310 CCCCCCCCCCOCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O03 compound treatment 1087080.0 27800.0 0.14 1038450.0 -7220.0 -0.04 1138150.0 91159.35483871 0.522114513958391 0.3551 0.6561 300 Bio1_000311 O[C@@H](CCc1ccccc1)/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O04 compound treatment 1011860.0 -47400.0 -0.23 934610.0 -111000.0 -0.66 1240930.0 193939.35483871 1.1107861850073 0.1263 0.0962 301 Bio1_000312 COCCCCCCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O05 compound treatment 1006640.0 -52600.0 -0.26 975070.0 -70600.0 -0.42 990940.0 -56050.64516129 -0.321029645363551 -0.5762 -0.9804 302 Bio1_000313 CCCCC[C@H](O)C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O06 compound treatment 1098610.0 39300.0 0.19 985120.0 -60500.0 -0.36 1138880.0 91889.35483871 0.526295583425853 0.2069 0.3107 1000032 Bio1_000314 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O07 compound treatment 1160920.0 102000.0 0.5 1082740.0 37100.0 0.22 1065760.0 18769.35483871 0.107501337589154 0.4761 0.8595 304 Bio1_000315 CCCCC[C@H](O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O08 compound treatment 1020040.0 -39200.0 -0.19 989970.0 -55700.0 -0.33 1175360.0 128369.35483871 0.735234506950508 0.1226 0.1479 305 Bio1_000316 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O09 compound treatment 1084250.0 25000.0 0.12 1122030.0 76400.0 0.45 1283850.0 236859.35483871 1.35661015972435 1.1158 0.7772 1000033 Bio1_000317 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O10 compound treatment 1039550.0 -19700.0 -0.1 1078810.0 33100.0 0.2 1159210.0 112219.35483871 0.642735504348447 0.4292 0.632 307 Bio1_000318 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O11 compound treatment 995070.0 -64200.0 -0.31 1006300.0 -39400.0 -0.23 1300040.0 253049.35483871 1.44933826202326 0.5205 0.3467 308 Bio1_000319 CCCCC/C=C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O12 compound treatment 1036560.0 -22700.0 -0.11 1091810.0 46100.0 0.27 1092260.0 45269.35483871 0.25927988675043 0.244 0.6201 309 Bio1_000320 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O13 compound treatment 1028190.0 -31100.0 -0.15 980960.0 -64700.0 -0.38 1221680.0 174689.35483871 1.00053195589958 0.2678 0.2473 310 Bio1_000321 CCCCC(C)(O)C/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O14 compound treatment 1068130.0 8850.0 0.04 1038680.0 -6990.0 -0.04 1094470.0 47479.35483871 0.271937645001239 0.158 0.5673 311 Bio1_000322 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O15 compound treatment 1063620.0 4340.0 0.02 993990.0 -51700.0 -0.31 984320.0 -62670.64516129 -0.358945645191764 -0.3724 -0.7874 312 Bio1_000323 CCCCC[C@H](O)/C=C/[C@H]1OC(O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O16 compound treatment 260020.0 -799000.0 -3.91 253500.0 -792000.0 -4.71 237440.0 -809550.64516129 -4.63669518472286 -7.6513 -0.9966 313 Bio1_000324 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O17 compound treatment 980230.0 -79100.0 -0.39 1004570.0 -41100.0 -0.24 1129860.0 82869.35483871 0.474633601786807 -0.0901 -0.1367 314 Bio1_000325 CCCCC[C@H](O)/C=C/[C@H]1OC(=O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O18 compound treatment 1094040.0 34800.0 0.17 1093410.0 47700.0 0.28 1074270.0 27279.35483871 0.156242298093398 0.3522 0.9626 315 Bio1_000326 CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O19 compound treatment 1028840.0 -30400.0 -0.15 977440.0 -68200.0 -0.41 1209400.0 162409.35483871 0.930198348967483 0.2169 0.2115 316 Bio1_000327 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O20 compound treatment 953600.0 -106000.0 -0.52 946730.0 -98900.0 -0.59 1094530.0 47539.35483871 0.27228129454651 -0.4806 -0.5799 1000034 Bio1_000328 CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O21 compound treatment 1113240.0 54000.0 0.26 1039400.0 -6270.0 -0.04 1050790.0 3799.35483871005 0.0217607760440862 0.1433 0.5362 318 Bio1_000329 CCCCCCCCCCCCCCCC(=O)NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O22 compound treatment 1062460.0 3180.0 0.02 980540.0 -65100.0 -0.39 1200010.0 153019.35483871 0.876417195132601 0.2914 0.304 319 Bio1_000330 CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)OCC[N+](C)(C)C)[C@H](O)/C=C/CCCCCCCCCCCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O23 mock treatment 951950.0 -107000.0 -0.52 1103040.0 57400.0 0.34 1113920.0 66929.35483871 0.383337372593194 0.1155 0.1575 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 O24 mock treatment 1034040.0 -25200.0 -0.12 1094720.0 49100.0 0.29 949690.0 -97300.64516129 -0.557288707737235 -0.2245 -0.3503 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P01 compound treatment 754110.0 -305000.0 -1.49 745540.0 -300000.0 -1.78 721920.0 -325070.64516129 -1.86183965650946 -2.9662 -0.9957 320 Bio1_000331 CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c(C(=O)/C=C/c3ccccc3)c4OC(C)(C)C=Cc4c2O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P02 compound treatment 432320.0 -627000.0 -3.06 411320.0 -634000.0 -3.77 412530.0 -634460.64516129 -3.63386853669841 -6.0444 -0.9962 321 Bio1_000332 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P03 compound treatment 1188190.0 129000.0 0.63 1203490.0 158000.0 0.94 1294640.0 247649.35483871 1.41840980294889 1.7244 0.9508 322 Bio1_000333 C[C@H]1O[C@H](C[C@H]1O)n2cnc3c(N)ncnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P04 compound treatment 1020020.0 -39300.0 -0.19 996030.0 -49600.0 -0.3 1067470.0 20479.35483871 0.117295349629373 -0.2134 -0.5752 10 Bio1_000334 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P05 compound treatment 591840.0 -467000.0 -2.28 631220.0 -414000.0 -2.46 691430.0 -355560.64516129 -2.03647090043124 -3.9172 -0.997 1000035 Bio1_000335 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P06 compound treatment 794020.0 -265000.0 -1.3 757780.0 -288000.0 -1.71 802410.0 -244580.64516129 -1.40083379152866 -2.5454 -0.9929 324 Bio1_000336 Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P07 compound treatment 320650.0 -739000.0 -3.61 299370.0 -746000.0 -4.44 320320.0 -726670.64516129 -4.16200061285544 -7.0487 -0.9964 1907744 Bio1_000337 CCCCN1C(=O)C2CC3C(=Nc4ccccc34)C(N2C1=O)c5cccc(O)c5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P08 compound treatment 757440.0 -302000.0 -1.47 832380.0 -213000.0 -1.27 677440.0 -369550.64516129 -2.11659851940355 -2.8057 -0.976 325 Bio1_000338 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1N)\C#N)/Sc2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P09 compound treatment 889440.0 -170000.0 -0.83 1019200.0 -26500.0 -0.16 1064840.0 17849.35483871 0.102232044561669 -0.5109 -0.6006 326 Bio1_000339 OC12CCN(C2=Nc3ccc(Cl)cc3C1=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P10 compound treatment 551410.0 -508000.0 -2.48 537370.0 -508000.0 -3.02 628330.0 -418660.64516129 -2.39787567220771 -4.5621 -0.9945 327 Bio1_000340 NCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P11 compound treatment 748900.0 -310000.0 -1.52 708820.0 -337000.0 -2.0 755490.0 -291500.64516129 -1.66956773593044 -2.9959 -0.9932 3103618 Bio1_000341 Cc1ccc2N=C3N(CCC3(O)C(=O)c2c1)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P12 compound treatment 114730.0 -945000.0 -4.61 83640.0 -962000.0 -5.72 71790.0 -975200.64516129 -5.58545430429136 -9.1921 -0.9957 329 Bio1_000342 CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C6CCCN6C(=O)C(NC5=O)C(C)C)c4nc23)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P13 compound treatment 1011210.0 -48100.0 -0.23 1113700.0 68000.0 0.4 1253120.0 206129.35483871 1.18060431762148 0.7796 0.6139 330 Bio1_000343 F[Al](F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P14 compound treatment 546510.0 -513000.0 -2.51 579040.0 -467000.0 -2.77 558880.0 -488110.64516129 -2.79565002085868 -4.6626 -0.9988 331 Bio1_000344 COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P15 compound treatment 42890.0 -1020000.0 -4.97 30440.0 -1020000.0 -6.04 26040.0 -1020950.64516129 -5.84748708256036 -9.7286 -0.9966 2081037 Bio1_000345 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(OC)c(OC)cc45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P16 compound treatment 693880.0 -365000.0 -1.79 671920.0 -374000.0 -2.22 623160.0 -423830.64516129 -2.42748680802522 -3.7154 -0.9923 333 Bio1_000346 NC(=S)/C(=C/c1ccc(O)c(O)c1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P17 compound treatment 320170.0 -739000.0 -3.61 267740.0 -778000.0 -4.63 287490.0 -759500.64516129 -4.35003418904278 -7.2672 -0.9948 1000037 Bio1_000347 COc1cc2ncnc(Nc3ccc(NC(=O)c4ccccc4)cc3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P18 compound treatment 399300.0 -660000.0 -3.22 362130.0 -684000.0 -4.06 326980.0 -720010.64516129 -4.12385551333038 -6.5894 -0.9942 3 Bio1_000348 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P19 compound treatment 725440.0 -334000.0 -1.63 692350.0 -353000.0 -2.1 788320.0 -258670.64516129 -1.48153415974309 -3.0101 -0.9887 1000038 Bio1_000349 CC(C(C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P20 compound treatment 53310.0 -1010000.0 -4.91 35860.0 -1010000.0 -6.0 32900.0 -1014090.64516129 -5.80819648455106 -9.658 -0.9964 336 Bio1_000350 COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P21 compound treatment 1102430.0 43100.0 0.21 1065560.0 19900.0 0.12 1083700.0 36709.35483871 0.210252551625128 0.3114 0.972 1000039 Bio1_000351 CC[C@]1(COC)[C@H](O)C[C@H](OC)[C@@]2(C(C)C)C3C[C@@]4(O)[C@H](OC(=O)c5ccccc5)C3[C@](C[C@H](OC)C12)(OC(=O)C)[C@@H](O)C[C@@H]4OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P22 compound treatment 288320.0 -771000.0 -3.77 220480.0 -825000.0 -4.91 151120.0 -895870.64516129 -5.13109233051913 -7.9703 -0.9917 3103677 Bio1_000352 CO[C@H]1/C=C\C=C(/C)\C[C@H](C)[C@H](O)[C@H](C)\C=C(/C)\C=C(/OC)\C(=O)OC1[C@@H](C)[C@@H](O)[C@H](C)[C@@]2(O)C[C@@H](O)[C@H](C)[C@H](O2)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P23 mock treatment 912870.0 -146000.0 -0.72 895200.0 -150000.0 -0.89 1199720.0 152729.35483871 0.874756222330458 -0.4246 -0.2946 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1275 P24 mock treatment 857490.0 -202000.0 -0.99 916160.0 -130000.0 -0.77 1006690.0 -40300.64516129 -0.230821639729962 -1.1471 -0.9017 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A01 compound treatment 770640.0 -365000.0 -1.78 741440.0 -388000.0 -2.31 724000.0 -383671.875 -2.19747775628251 -3.6296 -0.9942 3173 Maybridge2_000001 CCOC(=O)c1c(N)sc2CN(Cc3ccccc3)CCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A02 compound treatment 940260.0 -195000.0 -0.95 930610.0 -199000.0 -1.18 826140.0 -281531.875 -1.61247168038316 -2.1639 -0.9769 2074535 Maybridge2_000002 CCN(CC)C(=O)Oc1ccc(Br)cc1C(=O)Nc2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A03 compound treatment 1113890.0 -21600.0 -0.11 955680.0 -174000.0 -1.03 972170.0 -135501.875 -0.776085962118211 -1.1052 -0.8526 2074536 Maybridge2_000003 CN1CCc2ccccc2C1Cc3ccccc3NS(=O)(=O)c4cccc(c4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A04 compound treatment 1016980.0 -118000.0 -0.58 957930.0 -171000.0 -1.02 933670.0 -174001.875 -0.99659442033365 -1.4981 -0.9737 2074537 Maybridge2_000004 Fc1cccc(Cl)c1CN(Cc2c(F)cccc2Cl)OC(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A05 compound treatment 986080.0 -149000.0 -0.73 927650.0 -202000.0 -1.2 936450.0 -171221.875 -0.980671991402769 -1.6801 -0.981 2074538 Maybridge2_000005 CCN(CC)/C=C/c1nnnn1c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A06 compound treatment 1146140.0 10700.0 0.05 927040.0 -202000.0 -1.2 957720.0 -149951.875 -0.858848227604266 -1.1603 -0.7844 2074539 Maybridge2_000006 Brc1cc(Br)cc(CN2CCOCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A07 compound treatment 837120.0 -298000.0 -1.46 687960.0 -441000.0 -2.62 702770.0 -404901.875 -2.31907242038417 -3.6959 -0.9742 2074540 Maybridge2_000007 CN1C2CCC1CC(C2)NC(=O)Nc3ccc(OC(F)(F)F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A08 compound treatment 1197940.0 62500.0 0.31 966240.0 -163000.0 -0.97 1010210.0 -97461.875 -0.558212150416515 -0.7061 -0.6086 2074541 Maybridge2_000008 Clc1ccc(cc1)S(=O)(=O)Oc2cccc(c2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A09 compound treatment 831840.0 -304000.0 -1.48 729160.0 -400000.0 -2.38 694050.0 -413621.875 -2.36901615429686 -3.5982 -0.9802 1619298 Maybridge2_000009 CN1C2CCC1CC(C2)NC(=O)CSCc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A10 compound treatment 1138960.0 3520.0 0.02 910740.0 -219000.0 -1.3 1014310.0 -93361.875 -0.534729431489676 -1.0494 -0.7465 2074542 Maybridge2_000010 COc1ccc(cc1)S(=O)(=O)N2CCCC2c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A11 compound treatment 1046400.0 -89000.0 -0.44 983330.0 -146000.0 -0.87 999230.0 -108441.875 -0.621100017201074 -1.1112 -0.9638 1346942 Maybridge2_000011 CN1C2CCC1CC(C2)NC(=O)CSc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A12 compound treatment 1026760.0 -109000.0 -0.53 953400.0 -176000.0 -1.05 920160.0 -187511.875 -1.0739728429438 -1.5308 -0.9623 1121004 Maybridge2_000012 Clc1ccc(cc1)c2csc(n2)c3ccc(cc3)S(=O)(=O)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A13 compound treatment 1177130.0 41700.0 0.2 960190.0 -169000.0 -1.01 940840.0 -166831.875 -0.955528299673788 -1.0149 -0.7237 2074543 Maybridge2_000013 CCN(C(Cc1ccccc1)c2ccc(OC)cc2)C(=O)c3c(C)onc3c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A14 compound treatment 871080.0 -264000.0 -1.29 787900.0 -341000.0 -2.03 748890.0 -358781.875 -2.05492046991933 -3.1045 -0.981 2074544 Maybridge2_000014 CCn1cc(C(=O)Nc2ccccc2)c(=O)c3cc(Cl)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A15 compound treatment 1177300.0 41900.0 0.2 968980.0 -160000.0 -0.95 1089280.0 -18391.875 -0.105339324673794 -0.4934 -0.5029 2074545 Maybridge2_000015 Oc1c(Cl)cc(Cl)cc1C2N3CCCCC3Cn4cccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A16 compound treatment 1157290.0 21800.0 0.11 991370.0 -138000.0 -0.82 1025660.0 -82011.875 -0.469722392509281 -0.6834 -0.7181 2074546 Maybridge2_000016 COc1ccc(cc1Br)C2NN=C3C2N4CCC3CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A17 compound treatment 1189160.0 53700.0 0.26 1016270.0 -113000.0 -0.67 963270.0 -144401.875 -0.827060644666715 -0.7143 -0.6506 2074547 Maybridge2_000017 Cc1cc(C)c(NC(=O)N2CCCC2)c3CC(C)(C)C(=O)c31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A18 compound treatment 1243280.0 108000.0 0.53 1015150.0 -114000.0 -0.68 920740.0 -186931.875 -1.07065089733951 -0.7061 -0.5143 2074548 Maybridge2_000018 Cn1ncc(Br)c1NC(=O)CN2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A19 compound treatment 1045730.0 -89700.0 -0.44 918080.0 -211000.0 -1.26 1021050.0 -86621.875 -0.496126132570921 -1.2649 -0.8907 2074549 Maybridge2_000019 OC(=O)c1cc(NC(=O)/C=C/c2cccs2)ccc1N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A20 compound treatment 1093770.0 -41700.0 -0.2 899040.0 -230000.0 -1.37 945450.0 -162221.875 -0.929124559612147 -1.4448 -0.8664 1231779 Maybridge2_000020 Clc1cc(Cl)cc(NC(=O)N2CCN(Cc3ccccc3)CC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A21 compound treatment 983920.0 -152000.0 -0.74 884160.0 -245000.0 -1.46 914560.0 -193111.875 -1.1060468005024 -1.9079 -0.9664 2074550 Maybridge2_000021 CS/C(=N/c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A22 compound treatment 1075700.0 -59700.0 -0.29 964520.0 -165000.0 -0.98 925510.0 -182161.875 -1.04333075849048 -1.3369 -0.915 2074551 Maybridge2_000022 C(NC1Cc2ccccc2C1)c3nc(no3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A23 mock treatment 1184200.0 48800.0 0.24 872370.0 -257000.0 -1.53 967200.0 -140471.875 -0.804551599451477 -1.2093 -0.6936 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 A24 mock treatment 80160.0 -1060000.0 -5.16 791390.0 -338000.0 -2.01 906470.0 -201201.875 -1.15238221418975 -4.8025 -0.8496 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B01 compound treatment 1010140.0 -125000.0 -0.61 932280.0 -197000.0 -1.17 885600.0 -222071.875 -1.27191498101978 -1.7645 -0.9617 2074552 Maybridge2_000023 Fc1ccc(cc1)C(=O)C2CCN(Cc3c[nH]nc3c4ccccc4)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B02 compound treatment 968480.0 -167000.0 -0.82 895200.0 -234000.0 -1.39 884000.0 -223671.875 -1.28107896889367 -2.0146 -0.9777 2074553 Maybridge2_000024 O=S(=O)(Nc1ccc(cc1)N2CCCCC2)c3ccc(s3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B03 compound treatment 1104570.0 -30900.0 -0.15 1020100.0 -109000.0 -0.65 1037830.0 -69841.875 -0.400018809743517 -0.6932 -0.8912 1413006 Maybridge2_000025 Cc1cc(C)cc(NC(=O)N2CCN(Cc3ccncc3)CC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B04 compound treatment 983270.0 -152000.0 -0.74 907760.0 -222000.0 -1.32 984220.0 -123451.875 -0.707069678442989 -1.5983 -0.957 2074554 Maybridge2_000026 COc1cccc(NC(=O)Nc2cc(ccc2N3CCCC3)C(F)(F)F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B05 compound treatment 1034730.0 -101000.0 -0.49 981850.0 -148000.0 -0.88 916510.0 -191161.875 -1.0948781902811 -1.4227 -0.9569 1077004 Maybridge2_000027 Cc1ccc(cc1)C(=O)CN(Cc2ccccc2)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B06 compound treatment 1051890.0 -83600.0 -0.41 991330.0 -138000.0 -0.82 1034240.0 -73431.875 -0.420580507535554 -0.9524 -0.9443 2074555 Maybridge2_000028 OC(=O)CSCC(=O)Nc1cc(ccc1N2CCCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B07 compound treatment 1024990.0 -110000.0 -0.54 953370.0 -176000.0 -1.05 929120.0 -178551.875 -1.02265451085002 -1.5062 -0.9658 2074556 Maybridge2_000029 CN(C1CCCCC1)C(=O)c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B08 compound treatment 1100930.0 -34500.0 -0.17 1017890.0 -111000.0 -0.66 1014020.0 -93651.875 -0.536390404291819 -0.7898 -0.9086 2074557 Maybridge2_000030 OC(=O)CCC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B09 compound treatment 914640.0 -221000.0 -1.08 964640.0 -165000.0 -0.98 923560.0 -184111.875 -1.05449936871178 -1.7972 -0.9992 1442259 Maybridge2_000031 CN1CCc2c(C(=O)c3ccc(Cl)cc3)c(N)sc2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B10 compound treatment 1068450.0 -67000.0 -0.33 1132240.0 2870.0 0.02 1016230.0 -91441.875 -0.52373264604101 -0.4815 -0.7793 2074558 Maybridge2_000032 FC(F)(F)Oc1ccc(cc1)C2N(CCc3sccc23)S(=O)(=O)c4ccc(C#N)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B11 compound treatment 1081520.0 -53900.0 -0.26 951240.0 -178000.0 -1.06 945610.0 -162061.875 -0.928208160824758 -1.2996 -0.907 2074559 Maybridge2_000033 Fc1ccc(C(=O)Nc2ccc(cc2)N3CCCCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B12 compound treatment 1182720.0 47300.0 0.23 993280.0 -136000.0 -0.81 1149660.0 41988.125 0.240486667717068 -0.195 -0.2228 2074560 Maybridge2_000034 CCOC(=O)N1CCC(CC1)NC(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B13 compound treatment 987530.0 -148000.0 -0.72 763080.0 -366000.0 -2.18 962240.0 -145431.875 -0.832959961860531 -2.1557 -0.883 1269114 Maybridge2_000035 Cc1ccc(cc1Cl)S(=O)(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B14 compound treatment 1344260.0 209000.0 1.02 1010740.0 -119000.0 -0.71 1033960.0 -73711.875 -0.422184205413485 -0.062 -0.0473 1590511 Maybridge2_000036 O=C(N1CCCCCC1)c2ccc(cc2)C(=O)N3CCCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B15 compound treatment 1151010.0 15600.0 0.08 1129310.0 -57.6 0.0 967210.0 -140461.875 -0.804494324527265 -0.4208 -0.5207 2074561 Maybridge2_000037 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)N3CCCCC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B16 compound treatment 1046480.0 -89000.0 -0.43 1020930.0 -108000.0 -0.64 950790.0 -156881.875 -0.898539750083045 -1.142 -0.961 2074562 Maybridge2_000038 CC(C)(C)c1ccc(NC(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B17 compound treatment 1160610.0 25200.0 0.12 1067890.0 -61500.0 -0.37 1046780.0 -60891.875 -0.348757752573954 -0.3414 -0.6566 2074563 Maybridge2_000039 FC(F)(F)Oc1ccc(cc1)C2N(Cc3ccc4OCCc4c3)CCc5sccc25 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B18 compound treatment 1350630.0 215000.0 1.05 1112990.0 -16400.0 -0.1 1061060.0 -46611.875 -0.2669691607995 0.3966 0.3642 2074564 Maybridge2_000040 Fc1ccc(CN2CC(CC2=O)C(=O)Nc3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B19 compound treatment 1173070.0 37600.0 0.18 1117080.0 -12300.0 -0.07 1096160.0 -11511.875 -0.0659341768160742 0.0259 0.1241 2074565 Maybridge2_000041 CN(C1CCCCC1)C(=O)Nc2c(C)onc2c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B20 compound treatment 1143080.0 7640.0 0.04 957790.0 -172000.0 -1.02 1048610.0 -59061.875 -0.338276441443194 -0.7628 -0.7092 2074566 Maybridge2_000042 O=C(NCc1ccc(C#N)cc1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B21 compound treatment 1348360.0 213000.0 1.04 1009490.0 -120000.0 -0.71 1055480.0 -52191.875 -0.298928568509686 0.0164 0.0127 2074567 Maybridge2_000043 Clc1cc(Cl)cc(NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B22 compound treatment 927640.0 -208000.0 -1.02 847040.0 -282000.0 -1.68 830290.0 -277381.875 -1.58870258683526 -2.4727 -0.9795 2074568 Maybridge2_000044 CN(C)c1ccc(NC(=O)Nc2cccs2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B23 mock treatment 1278990.0 144000.0 0.7 1029470.0 -99900.0 -0.59 1045120.0 -62551.875 -0.358265389993113 -0.1449 -0.1469 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 B24 mock treatment 1101010.0 -34400.0 -0.17 994000.0 -135000.0 -0.8 1005650.0 -102021.875 -0.584329515857097 -0.8992 -0.8914 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C01 compound treatment 1011760.0 -124000.0 -0.6 971360.0 -158000.0 -0.94 934260.0 -173411.875 -0.993215199805154 -1.4648 -0.9799 1180495 Maybridge2_000045 CN(C)CCNS(=O)(=O)c1ccc(s1)c2csc(C)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C02 compound treatment 1046830.0 -88600.0 -0.43 1015520.0 -114000.0 -0.68 1019840.0 -87831.875 -0.50305639840055 -0.9313 -0.9823 2074569 Maybridge2_000046 CCN(CC)C(=O)Oc1ccc(Br)cc1C(=O)Nc2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C03 compound treatment 1144060.0 8620.0 0.04 1016240.0 -113000.0 -0.67 1058010.0 -49661.875 -0.2844380126841 -0.5283 -0.7221 1724527 Maybridge2_000047 Clc1ccc(cc1)C2N(Cc3ccccc3)CCC4CCCCN24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C04 compound treatment 1203690.0 68200.0 0.33 921140.0 -208000.0 -1.24 1050610.0 -57061.875 -0.326821456600834 -0.7111 -0.5373 2074570 Maybridge2_000048 Fc1cccc(Cl)c1CN(Cc2c(F)cccc2Cl)OC(=O)C3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C05 compound treatment 56060.0 -1080000.0 -5.27 49650.0 -1080000.0 -6.42 37140.0 -1070531.875 -6.13146320069436 -10.2917 -0.9967 1401898 Maybridge2_000049 CN(C)CC(O)Cn1c2ccc(Cl)cc2c3cc(Cl)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C06 compound treatment 1077330.0 -58100.0 -0.28 1016970.0 -112000.0 -0.67 1006500.0 -101171.875 -0.579461147299094 -0.8844 -0.9519 2074571 Maybridge2_000050 Brc1cc(Br)cc(CN2CCSCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C07 compound treatment 1062240.0 -73200.0 -0.36 1010090.0 -119000.0 -0.71 929390.0 -178281.875 -1.0211080878963 -1.2055 -0.9319 1413543 Maybridge2_000051 CN1C2CCC1CC(C2)NC(=O)Nc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C08 compound treatment 1082240.0 -53200.0 -0.26 1036200.0 -93200.0 -0.55 1048020.0 -59651.875 -0.341655661971691 -0.6672 -0.9519 2074572 Maybridge2_000052 CSCc1c(C)nn(C(=O)N(C)C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C09 compound treatment 988710.0 -147000.0 -0.72 970180.0 -159000.0 -0.95 1029800.0 -77871.875 -0.446010573885594 -1.2179 -0.9602 1241925 Maybridge2_000053 CN1C2CCC1CC(C2)NC(=O)CSCc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C10 compound treatment 1219470.0 84000.0 0.41 1014780.0 -115000.0 -0.68 959520.0 -148151.875 -0.848538741246141 -0.6463 -0.5556 2074573 Maybridge2_000054 Clc1ccc(c(Cl)c1)S(=O)(=O)N2CCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C11 compound treatment 1465200.0 330000.0 1.61 1124800.0 -4570.0 -0.03 1120000.0 12328.125 0.0706092425048626 0.9553 0.5923 2074574 Maybridge2_000055 COc1cccc(c1)c2c(OC)cccc2C3CCCCN(C)C3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C12 compound treatment 1137460.0 2020.0 0.01 1116660.0 -12700.0 -0.08 1068130.0 -39541.875 -0.226475789381756 -0.1687 -0.706 1129748 Maybridge2_000056 CC(C)(C)c1csc(n1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C13 compound treatment 1250400.0 115000.0 0.56 1005960.0 -123000.0 -0.73 1171630.0 63958.125 0.366319676210398 0.1121 0.1127 2074575 Maybridge2_000057 CCN(C(Cc1ccccc1)c2ccc(OC)cc2)C(=O)c3c(C)onc3c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C14 compound treatment 1095320.0 -40100.0 -0.2 896700.0 -233000.0 -1.38 932640.0 -175031.875 -1.00249373752747 -1.4908 -0.8668 2074576 Maybridge2_000058 CCn1cc(C(=O)Nc2ccc(cc2)C(F)(F)F)c(=O)c3cc(Cl)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C15 compound treatment 1132480.0 -2960.0 -0.01 1049870.0 -79500.0 -0.47 1015410.0 -92261.875 -0.528429189826378 -0.5864 -0.8269 2074577 Maybridge2_000059 Fc1cccc(F)c1C(=O)N2CCCCC2Cn3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C16 compound treatment 1279240.0 144000.0 0.7 975550.0 -154000.0 -0.91 987640.0 -120031.875 -0.687481654362553 -0.5194 -0.3868 1396629 Maybridge2_000060 CN1N=C2C(C1c3ccc(Cl)c(Cl)c3)N4CCC2CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C17 compound treatment 1248090.0 113000.0 0.55 1053310.0 -76100.0 -0.45 1077480.0 -30191.875 -0.172923735243721 -0.0432 -0.0589 2074578 Maybridge2_000061 Cc1cc(C)c(NC(=O)N(CC=C)CC=C)c2CC(C)(C)C(=O)c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C18 compound treatment 1150770.0 15300.0 0.07 1095490.0 -33900.0 -0.2 1080980.0 -26691.875 -0.15287751176959 -0.1613 -0.6117 2074579 Maybridge2_000062 COC(=O)c1cn(Cc2ccc(cc2)C(F)(F)F)cc(F)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C19 compound treatment 1378920.0 243000.0 1.19 1104480.0 -24900.0 -0.15 1226260.0 118588.125 0.679212587179474 0.9935 0.7211 2074580 Maybridge2_000063 CN(C)c1ccc(CO)c(F)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C20 compound treatment 1370560.0 235000.0 1.15 1020330.0 -109000.0 -0.65 1047160.0 -60511.875 -0.346581305453906 0.0888 0.0651 1253399 Maybridge2_000064 Fc1ccc(C(=O)N2CCN(Cc3ccc4OCOc4c3)CC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C21 compound treatment 1210440.0 75000.0 0.37 1007360.0 -122000.0 -0.73 995360.0 -112311.875 -0.643265412871042 -0.5787 -0.5583 2074581 Maybridge2_000065 CS/C(=N\c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C22 compound treatment 1200360.0 64900.0 0.32 1069300.0 -60100.0 -0.36 1081970.0 -25701.875 -0.147207294272622 -0.1081 -0.2163 1713118 Maybridge2_000066 Fc1cccc(Cl)c1CN2CCN(CC2)C(=O)Nc3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C23 mock treatment 1317440.0 182000.0 0.89 980970.0 -148000.0 -0.88 1073300.0 -34371.875 -0.196864653564254 -0.1098 -0.0866 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 C24 mock treatment 1234720.0 99300.0 0.49 997680.0 -132000.0 -0.78 943770.0 -163901.875 -0.93874674687973 -0.7141 -0.5429 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D01 compound treatment 711450.0 -424000.0 -2.07 537410.0 -592000.0 -3.52 600530.0 -507141.875 -2.90465124552563 -4.9054 -0.9787 2074582 Maybridge2_000067 O=S(=O)(Oc1ccccc1N2CCCCC2)c3ccc(s3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D02 compound treatment 1171250.0 35800.0 0.17 1131320.0 1950.0 0.01 971420.0 -136251.875 -0.780381581434096 -0.3428 -0.4286 2074583 Maybridge2_000068 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccc(cc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D03 compound treatment 151100.0 -984000.0 -4.81 109160.0 -1020000.0 -6.07 86880.0 -1020791.875 -5.84657772766486 -9.6548 -0.9952 1547353 Maybridge2_000069 Cc1[nH]c2ccccc2c1CN3CCN(CC3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D04 compound treatment 1003860.0 -132000.0 -0.64 926730.0 -203000.0 -1.2 953030.0 -154641.875 -0.885710167059601 -1.5782 -0.9695 2074584 Maybridge2_000070 CC(C)(C)c1ccc(NC(=O)Nc2cc(ccc2N3CCCC3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D05 compound treatment 1170570.0 35100.0 0.17 1030290.0 -99100.0 -0.59 1122340.0 14668.125 0.0840115747704243 -0.1926 -0.3109 2074585 Maybridge2_000071 FC(F)(F)Oc1ccc(cc1)C2N(Cc3ccccc3)CCc4sccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D06 compound treatment 1284110.0 149000.0 0.73 1173080.0 43700.0 0.26 1114320.0 6648.125 0.0380770855525588 0.5914 0.7657 2074586 Maybridge2_000072 Fc1ccc(CNC(=O)C2CN(Cc3ccco3)C(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D07 compound treatment 1115370.0 -20100.0 -0.1 982030.0 -147000.0 -0.88 996260.0 -111411.875 -0.638110669691979 -0.9309 -0.8553 2074587 Maybridge2_000073 CCOC(=O)C1CCN(CC(=O)c2ccc(C)cc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D08 compound treatment 1049190.0 -86300.0 -0.42 1038760.0 -90600.0 -0.54 1050200.0 -57471.875 -0.329169728493518 -0.7444 -0.9807 2074588 Maybridge2_000074 OC(=O)CSCC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D09 compound treatment 1285040.0 150000.0 0.73 1202420.0 73100.0 0.43 1045090.0 -62581.875 -0.358437214765749 0.4658 0.5049 2074589 Maybridge2_000075 O=C(CC1NCCNC1=O)NC2Cc3ccccc3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D10 compound treatment 1154960.0 19500.0 0.1 1098730.0 -30600.0 -0.18 1122260.0 14588.125 0.0835533753767299 -0.0019 -0.0085 2074590 Maybridge2_000076 Fc1cccc(c1)S(=O)(=O)N2CCc3sccc3C2c4ccc(OC(F)(F)F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D11 compound treatment 1062080.0 -73400.0 -0.36 958530.0 -171000.0 -1.02 972890.0 -134781.875 -0.771962167574961 -1.2392 -0.935 2074591 Maybridge2_000077 Clc1cccc(NC(=O)Nc2ccc(cc2)N3CCCCC3)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D12 compound treatment 1245380.0 110000.0 0.54 1170580.0 41200.0 0.25 1083740.0 -23931.875 -0.137069632687133 0.3725 0.6145 2074592 Maybridge2_000078 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D13 compound treatment 1113330.0 -22100.0 -0.11 987300.0 -142000.0 -0.84 1324850.0 217178.125 1.24388606498363 0.168 0.1115 1119500 Maybridge2_000079 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)Nc3ccc(cc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D14 compound treatment 1199360.0 63900.0 0.31 1007690.0 -122000.0 -0.72 1052480.0 -55191.875 -0.316111045773227 -0.42 -0.4946 1006240 Maybridge2_000080 OC(CN1CCCC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D15 compound treatment 1262570.0 127000.0 0.62 862450.0 -267000.0 -1.59 917720.0 -189951.875 -1.08794792445147 -1.1859 -0.5865 2074593 Maybridge2_000081 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccc(s3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D16 compound treatment 1351730.0 216000.0 1.06 1048260.0 -81100.0 -0.48 1096960.0 -10711.875 -0.06135218287913 0.2962 0.2547 2074594 Maybridge2_000082 Cc1ccc(cc1C)C(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D17 compound treatment 1125840.0 -9600.0 -0.05 1118770.0 -10600.0 -0.06 1026300.0 -81371.875 -0.466056797359725 -0.3326 -0.7036 2074595 Maybridge2_000083 FC(F)(F)Oc1ccc(cc1)C2N(Cc3nc4ccccc4s3)CCc5sccc25 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D18 compound treatment 1206080.0 70600.0 0.35 1102330.0 -27000.0 -0.16 1029280.0 -78391.875 -0.448988869944608 -0.1528 -0.2596 2074596 Maybridge2_000084 COc1ccc(NC(=O)C2CN(Cc3ccc(F)cc3)C(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D19 compound treatment 1275260.0 140000.0 0.68 1189130.0 59800.0 0.36 1176250.0 68578.125 0.392780691196251 0.8263 0.956 2074597 Maybridge2_000085 CN(Cc1ccccc1)S(=O)(=O)c2cn(C)cn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D20 compound treatment 1011840.0 -124000.0 -0.6 836570.0 -293000.0 -1.74 917220.0 -190451.875 -1.09081167066207 -1.9837 -0.9263 2074598 Maybridge2_000086 CN(C)c1ccc(NC(=O)Nc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D21 compound treatment 1408340.0 273000.0 1.33 1075220.0 -54100.0 -0.32 1074350.0 -33321.875 -0.190850786522015 0.4737 0.3421 2074599 Maybridge2_000087 COc1cccc(NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D22 compound treatment 1050160.0 -85300.0 -0.42 967240.0 -162000.0 -0.96 983330.0 -124341.875 -0.71216714669784 -1.2084 -0.9522 2074600 Maybridge2_000088 COc1ccc(Cl)cc1NC(=O)Nc2ccc(cc2)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D23 mock treatment 1079300.0 -56100.0 -0.27 993690.0 -136000.0 -0.81 1157820.0 50148.125 0.287223005873899 -0.4584 -0.5097 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 D24 mock treatment 1135840.0 396.0 0.0 1025080.0 -104000.0 -0.62 1057280.0 -50391.875 -0.288619082151562 -0.5236 -0.7654 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E01 compound treatment 1110010.0 -25400.0 -0.12 1045670.0 -83700.0 -0.5 1036840.0 -70831.875 -0.405689027240486 -0.5933 -0.9072 1137390 Maybridge2_000089 Fc1cccc(Cl)c1CN2CCN(CC2)C(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E02 compound treatment 1102110.0 -33300.0 -0.16 1179890.0 50500.0 0.3 1099040.0 -8631.875 -0.0494389986430751 0.0509 0.1474 2074601 Maybridge2_000090 Fc1ccc(NC(=O)CCN2CCCCC2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E03 compound treatment 1039370.0 -96100.0 -0.47 1109120.0 -20200.0 -0.12 1089690.0 -17981.875 -0.10299105278111 -0.4 -0.8074 1518121 Maybridge2_000091 O=C(CCN1CCCC1)c2ccc(cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E04 compound treatment 1136690.0 1250.0 0.01 1231220.0 102000.0 0.61 991810.0 -115861.875 -0.663598010966231 -0.0299 -0.0333 2074602 Maybridge2_000092 FC(F)(F)c1cc(Br)ccc1/C=C/c2noc(CN3CCSCC3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E05 compound treatment 1007220.0 -128000.0 -0.63 935790.0 -194000.0 -1.15 948030.0 -159641.875 -0.914347629165502 -1.5542 -0.9726 1636659 Maybridge2_000093 CN1CCN(CC1)c2cc(nc3ccccc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E06 compound treatment 1159850.0 24400.0 0.12 1296850.0 167000.0 1.0 1018640.0 -89031.875 -0.509929389305966 0.3494 0.3106 2074603 Maybridge2_000094 CN(C)/C=C(\C#N)/C(=O)Nc1cc(ccc1Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E07 compound treatment 1053600.0 -81800.0 -0.4 1080560.0 -48800.0 -0.29 951630.0 -156041.875 -0.893728656449253 -0.9144 -0.8954 1223321 Maybridge2_000095 CN1C2CCC1CC(C2)NC(=O)Nc3ccc(Br)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E08 compound treatment 1119620.0 -15800.0 -0.08 1181450.0 52100.0 0.31 1048000.0 -59671.875 -0.341770211820114 -0.0631 -0.135 2074604 Maybridge2_000096 O=C(/C=C\1/NC(=O)CS1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E09 compound treatment 1159740.0 24300.0 0.12 1204080.0 74700.0 0.44 1060580.0 -47091.875 -0.269718357161667 0.1693 0.3176 1322935 Maybridge2_000097 CN1C2CCC1CC(C2)NC(=O)CS(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E10 compound treatment 1237150.0 102000.0 0.5 1082170.0 -47200.0 -0.28 1092840.0 -14831.875 -0.0849494516543926 0.0758 0.1314 2074605 Maybridge2_000098 CN(C)/C=C/C(=O)c1nnn(c1C)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E11 compound treatment 908100.0 -227000.0 -1.11 909280.0 -220000.0 -1.31 890180.0 -217491.875 -1.24568306573078 -2.1161 -0.9977 2074606 Maybridge2_000099 C(Oc1cnc(nc1)N2CCNCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E12 compound treatment 1209540.0 74100.0 0.36 1073780.0 -55600.0 -0.33 923240.0 -184431.875 -1.05633216628656 -0.5917 -0.5081 2074607 Maybridge2_000100 CN(C)/C=C/C(=O)c1ccc(o1)c2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E13 compound treatment 1232080.0 96600.0 0.47 1035870.0 -93500.0 -0.56 1115880.0 8208.125 0.0470119737296 -0.0213 -0.0291 1608666 Maybridge2_000101 CCN(C(Cc1ccccc1)c2ccc(OC)cc2)C(=O)c3sc4ccccc4c3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E14 compound treatment 748800.0 -387000.0 -1.89 616800.0 -513000.0 -3.05 584120.0 -523551.875 -2.9986393961572 -4.5817 -0.9801 2074608 Maybridge2_000102 CN1C/C(=C\c2cccc3ccccc23)/C(=O)\C(=C\c4cccc5ccccc45)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E15 compound treatment 699930.0 -436000.0 -2.13 623430.0 -506000.0 -3.01 543810.0 -563861.875 -3.22951461565498 -4.8301 -0.9857 2074609 Maybridge2_000103 CN1CCN(Cc2nc(/C=C/c3cc(cc(c3)C(F)(F)F)C(F)(F)F)no2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E16 compound treatment 1155760.0 20300.0 0.1 1067110.0 -62300.0 -0.37 1109300.0 1628.125 0.00932507359823407 -0.1511 -0.394 2074610 Maybridge2_000104 CSc1nsc(SC)c1NC(=O)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E17 compound treatment 1279620.0 144000.0 0.7 1056000.0 -73400.0 -0.44 1244220.0 136548.125 0.782078351063871 0.6063 0.5322 1127399 Maybridge2_000105 CC1CN(Cc2c(F)cccc2Cl)CC(C)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E18 compound treatment 1141280.0 5840.0 0.03 1061030.0 -68300.0 -0.41 1055200.0 -52471.875 -0.300532266387616 -0.3917 -0.7737 2074611 Maybridge2_000106 Clc1ccc(Cl)c(NC(=O)CC2NCCCNC2=O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E19 compound treatment 1226130.0 90700.0 0.44 1156230.0 26900.0 0.16 1195360.0 87688.125 0.502233071365005 0.638 0.9266 2074612 Maybridge2_000107 CN(C)CCCN/C(=N\O)/c1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E20 compound treatment 1298260.0 163000.0 0.8 1155950.0 26600.0 0.16 1038890.0 -68781.875 -0.393947667777066 0.3231 0.3583 1451184 Maybridge2_000108 Fc1cccc(Cl)c1C(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E21 compound treatment 1201720.0 66300.0 0.32 1113140.0 -16200.0 -0.1 1106320.0 -1351.875 -0.00774285381688303 0.1268 0.3751 1083885 Maybridge2_000109 CN(Cc1ccccc1)C(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E22 compound treatment 1004320.0 -131000.0 -0.64 994840.0 -135000.0 -0.8 1039360.0 -68311.875 -0.391255746339111 -1.0576 -0.9641 1267524 Maybridge2_000110 CCN(CC)c1ccc(NC(=O)c2ccccc2C(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E23 mock treatment 1135640.0 196.0 0.0 1105920.0 -23400.0 -0.14 1128990.0 21318.125 0.122099399371273 -0.0095 -0.051 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 E24 mock treatment 1112560.0 -22900.0 -0.11 1087270.0 -42100.0 -0.25 1204640.0 96968.125 0.555384201033557 0.1116 0.1801 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F01 compound treatment 1051310.0 -84100.0 -0.41 1009540.0 -120000.0 -0.71 1152810.0 45138.125 0.258528268843786 -0.4995 -0.5792 2074613 Maybridge2_000111 OC(=O)c1ccccc1C(=O)N2CCN(CC2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F02 compound treatment 1271240.0 136000.0 0.66 1024130.0 -105000.0 -0.63 1202080.0 94408.125 0.540721820435336 0.3339 0.3149 2074614 Maybridge2_000112 Cc1onc(c1C(=O)Nc2ccc(cc2)N3CCCCC3)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F03 compound treatment 756880.0 -379000.0 -1.85 481970.0 -647000.0 -3.85 561440.0 -546231.875 -3.12853892426957 -5.0968 -0.9627 1181710 Maybridge2_000113 Cc1[nH]c2ccccc2c1CN3CCN(CC3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F04 compound treatment 1104290.0 -31200.0 -0.15 1089130.0 -40200.0 -0.24 1111930.0 4258.125 0.0243883786659381 -0.2119 -0.7446 2074615 Maybridge2_000114 C(N1CCC2(CC1)Nc3ccccc3S2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F05 compound treatment 1167480.0 32000.0 0.16 1061120.0 -68200.0 -0.41 1086880.0 -20791.875 -0.119085306484627 -0.2127 -0.4716 2074616 Maybridge2_000115 FC(F)(F)Oc1ccc(cc1)C2N(Cc3ccccn3)CCc4sccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F06 compound treatment 1099760.0 -35700.0 -0.17 1008320.0 -121000.0 -0.72 1083950.0 -23721.875 -0.135866859278685 -0.5947 -0.7898 2074617 Maybridge2_000116 CC(C)(CC(=O)NC1CCN(Cc2ccccc2)CC1)Sc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F07 compound treatment 1146090.0 10600.0 0.05 1018510.0 -111000.0 -0.66 1438410.0 330738.125 1.89430010433286 0.7431 0.3704 2074618 Maybridge2_000117 CCOC(=O)C1CCN(CC(=O)c2ccc(OC)cc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F08 compound treatment 1159580.0 24100.0 0.12 1021010.0 -108000.0 -0.64 1022600.0 -85071.875 -0.487248519318092 -0.5852 -0.7169 1943800 Maybridge2_000118 CN1CCN(CC(=O)N2c3ccccc3Sc4ccccc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F09 compound treatment 1235080.0 99600.0 0.49 1058400.0 -71000.0 -0.42 1183400.0 75728.125 0.433732262007689 0.2878 0.3706 1147671 Maybridge2_000119 Cc1nnsc1C(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F10 compound treatment 1114770.0 -20700.0 -0.1 1100400.0 -29000.0 -0.17 1054930.0 -52741.875 -0.302078689341335 -0.3322 -0.9173 2074619 Maybridge2_000120 O=C(CN1CCN(CC1)c2ccccc2)N3c4ccccc4Sc5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F11 compound treatment 1064170.0 -71300.0 -0.35 959650.0 -170000.0 -1.01 983070.0 -124601.875 -0.713656294727347 -1.1958 -0.9311 1636373 Maybridge2_000121 Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)N3CCCCC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F12 compound treatment 1245600.0 110000.0 0.54 1447740.0 318000.0 1.89 1095920.0 -11751.875 -0.0673087749971574 1.3649 0.6931 2074620 Maybridge2_000122 CCOC(=O)N1CCC(CC1)NC(=O)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F13 compound treatment 1131410.0 -4030.0 -0.02 1077600.0 -51800.0 -0.31 1097460.0 -10211.875 -0.0584884366685399 -0.2229 -0.7099 1861722 Maybridge2_000123 O=C(Nc1ccccc1N2CCCCC2)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F14 compound treatment 1177080.0 41600.0 0.2 1100500.0 -28900.0 -0.17 1129390.0 21718.125 0.124390396339745 0.0902 0.3069 2074621 Maybridge2_000124 CN(CCc1ccccn1)S(=O)(=O)c2ccc3OCCc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F15 compound treatment 1208820.0 73400.0 0.36 1065980.0 -63400.0 -0.38 1000400.0 -107271.875 -0.614398851068293 -0.3654 -0.4538 2074622 Maybridge2_000125 Fc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3ccc(s3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F16 compound treatment 1192680.0 57200.0 0.28 1287040.0 158000.0 0.94 1045950.0 -61721.875 -0.353511571283534 0.4987 0.4794 2074623 Maybridge2_000126 Fc1ccc(c(F)c1)S(=O)(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F17 compound treatment 1356820.0 221000.0 1.08 1092730.0 -36600.0 -0.22 1120420.0 12748.125 0.0730147893217583 0.5408 0.4891 2074624 Maybridge2_000127 CS(=O)(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F18 compound treatment 1180130.0 44700.0 0.22 1167230.0 37900.0 0.23 1060530.0 -47141.875 -0.270004731782726 0.1002 0.242 2074625 Maybridge2_000128 Cc1ccc(NC(=O)C2CN(Cc3ccc(F)cc3)C(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F19 compound treatment 894340.0 -241000.0 -1.18 774050.0 -355000.0 -2.11 844070.0 -263601.875 -1.5097777412714 -2.7717 -0.972 1430320 Maybridge2_000129 COc1ccc-2c(NC(c3cccn32)c4ccc(cc4)N(C)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F20 compound treatment 1021380.0 -114000.0 -0.56 988640.0 -141000.0 -0.84 995210.0 -112461.875 -0.644124536734219 -1.1768 -0.9855 2074626 Maybridge2_000130 CN(C)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F21 compound treatment 1198300.0 62900.0 0.31 1053190.0 -76200.0 -0.45 1081310.0 -26361.875 -0.150987439270601 -0.1714 -0.3019 2074627 Maybridge2_000131 CC(C)(C)c1ccc(NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F22 compound treatment 1210000.0 74600.0 0.36 1140450.0 11100.0 0.07 1250080.0 142408.125 0.815641456651987 0.7193 0.803 2074628 Maybridge2_000132 CN(C)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F23 mock treatment 1155870.0 20400.0 0.1 1100120.0 -29200.0 -0.17 1099770.0 -7901.875 -0.0452579291756135 -0.0689 -0.3353 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 F24 mock treatment 1070400.0 -65000.0 -0.32 1112380.0 -17000.0 -0.1 1000070.0 -107601.875 -0.616288923567283 -0.5976 -0.8529 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G01 compound treatment 1118740.0 -16700.0 -0.08 995120.0 -134000.0 -0.8 1015270.0 -92401.875 -0.529231038765343 -0.8136 -0.8464 1693364 Maybridge2_000133 CC(C)N1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G02 compound treatment 1116380.0 -19100.0 -0.09 1122080.0 -7290.0 -0.04 1037120.0 -70551.875 -0.404085329362555 -0.3121 -0.7485 2074629 Maybridge2_000134 Fc1ccc(NC(=O)CN2CCCCC2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G03 compound treatment 1121830.0 -13600.0 -0.07 1126440.0 -2930.0 -0.02 1137800.0 30128.125 0.172558607601871 0.0512 0.2755 1601195 Maybridge2_000135 CC1CC(C)CN(Cc2cc(Cl)c(O)c(Cl)c2)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G04 compound treatment 1125440.0 -10000.0 -0.05 1091080.0 -38300.0 -0.23 1110270.0 2598.125 0.0148807412467789 -0.1511 -0.6475 2074630 Maybridge2_000136 Cc1cc(cc(C)c1F)S(=O)(=O)N2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G05 compound treatment 868320.0 -267000.0 -1.31 838590.0 -291000.0 -1.73 892520.0 -215151.875 -1.23228073346522 -2.4633 -0.9883 1636659 Maybridge2_000137 CN1CCN(CC1)c2cc(nc3ccccc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G06 compound treatment 1177410.0 42000.0 0.21 1102120.0 -27200.0 -0.16 1093570.0 -14101.875 -0.080768382186931 -0.0218 -0.0797 2074631 Maybridge2_000138 O=C(N1CCSCC1)C2(CC3CC4CC(C3)C2)C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G07 compound treatment 1132970.0 -2470.0 -0.01 1146560.0 17200.0 0.1 1296270.0 188598.125 1.0801943315863 0.6757 0.6227 1354633 Maybridge2_000139 CN1C2CCC1CC(C2)NC(=O)Nc3ccc(F)cc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G08 compound treatment 1170840.0 35400.0 0.17 1215070.0 85700.0 0.51 1190150.0 82478.125 0.472392835850656 0.6668 0.9312 2074632 Maybridge2_000140 CN(C)/C=C/C(=O)c1nnn(c1C)c2cccc(Cl)c2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G09 compound treatment 1203300.0 67900.0 0.33 1110340.0 -19000.0 -0.11 1050520.0 -57151.875 -0.32733693091874 -0.0629 -0.1312 1360057 Maybridge2_000141 CN1C2CCC1CC(C2)NC(=O)CS(=O)(=O)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G10 compound treatment 1243850.0 108000.0 0.53 1301370.0 172000.0 1.02 1156410.0 48738.125 0.279147241560035 1.0575 0.8923 2074633 Maybridge2_000142 CN(C)/C=C/C(=O)c1nnn(c1C)c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G11 compound treatment 1178880.0 43400.0 0.21 1278560.0 149000.0 0.89 1281200.0 173528.125 0.993881020799116 1.2086 0.8959 2074634 Maybridge2_000143 N#CCCCN(Cc1ccccc1)Cc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G12 compound treatment 1327890.0 192000.0 0.94 1370640.0 241000.0 1.43 1050560.0 -57111.875 -0.327107831221893 1.1824 0.6771 2074635 Maybridge2_000144 CN(C)/C=C/C(=O)c1ccc(C)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G13 compound treatment 1030110.0 -105000.0 -0.51 965850.0 -164000.0 -0.97 1013120.0 -94551.875 -0.541545147470881 -1.1712 -0.9551 2074636 Maybridge2_000145 CN(C)c1ccc(C2=NCCCN2)c(SCc3cccc(c3)C(F)(F)F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G14 compound treatment 1240440.0 105000.0 0.51 1061600.0 -67800.0 -0.4 1014520.0 -93151.875 -0.533526658081228 -0.2445 -0.2901 2074637 Maybridge2_000146 CN1C/C(=C\c2cccs2)/C(=O)\C(=C\c3cccs3)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G15 compound treatment 1076500.0 -58900.0 -0.29 1055790.0 -73600.0 -0.44 1038650.0 -69021.875 -0.395322265958149 -0.6471 -0.9861 2074638 Maybridge2_000147 FC(F)(F)c1cc(/C=C/c2noc(CN3CCCCCC3)n2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G16 compound treatment 1136830.0 1390.0 0.01 91040.0 -1040000.0 -6.17 1099630.0 -8041.875 -0.0460597781145788 -3.5875 -0.581 2074639 Maybridge2_000148 COc1ccc(cc1)C2N(C)C(=O)c3ccccc3S2(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G17 compound treatment 1098440.0 -37000.0 -0.18 1059950.0 -69400.0 -0.41 1049930.0 -57741.875 -0.330716151447236 -0.5336 -0.9547 2074640 Maybridge2_000149 CN(C)c1ccc(/C=C/C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G18 compound treatment 1155520.0 20100.0 0.1 1123540.0 -5830.0 -0.03 1102910.0 -4761.875 -0.0272736029731076 0.0209 0.1941 1007333 Maybridge2_000150 CN1CCN(CC(O)c2ccccc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G19 compound treatment 1075310.0 -60100.0 -0.29 972590.0 -157000.0 -0.93 1098570.0 -9101.875 -0.0521309200810298 -0.738 -0.7539 2074641 Maybridge2_000151 CN(C)CCCNS(=O)(=O)c1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G20 compound treatment 1359630.0 224000.0 1.1 1219100.0 89700.0 0.53 1103110.0 -4561.875 -0.0261281044888716 0.9254 0.7593 1686641 Maybridge2_000152 Clc1ccsc1C(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G21 compound treatment 1213670.0 78200.0 0.38 1093830.0 -35500.0 -0.21 1143140.0 35468.125 0.203143417130973 0.2159 0.4483 2074642 Maybridge2_000153 CC1CN(CCCNC(=O)Nc2ccc(Cl)cc2)CC(C)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G22 compound treatment 828410.0 -307000.0 -1.5 773890.0 -355000.0 -2.11 795420.0 -312251.875 -1.78842024756182 -3.1191 -0.9904 2074643 Maybridge2_000154 NC(=O)C1CCN(CC1)c2c(Cl)cncc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G23 mock treatment 1194620.0 59200.0 0.29 1069120.0 -60200.0 -0.36 1101830.0 -5841.875 -0.0334592947879823 -0.0592 -0.1283 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 G24 mock treatment 1163250.0 27800.0 0.14 1217800.0 88400.0 0.53 1176540.0 68868.125 0.394441663998393 0.6098 0.9084 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H01 compound treatment 1117200.0 -18200.0 -0.09 1030720.0 -98600.0 -0.59 1285390.0 177718.125 1.01787921404386 0.1975 0.1677 2074644 Maybridge2_000155 Fc1ccc(cc1)N2C(=O)CCN(Cc3ccccc3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H02 compound treatment 1186570.0 51100.0 0.25 1375270.0 246000.0 1.46 1175040.0 67368.125 0.385850425366623 1.2112 0.7902 2074645 Maybridge2_000156 Clc1ccc2[nH]c(cc2c1)C(=O)Nc3ccc(cc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H03 compound treatment 1024880.0 -111000.0 -0.54 991300.0 -138000.0 -0.82 1002260.0 -105411.875 -0.603745715164898 -1.1345 -0.9836 1426576 Maybridge2_000157 CN1CCN(CC1)c2ccc(NC(=O)c3cccs3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H04 compound treatment 1085560.0 -49900.0 -0.24 1161120.0 31800.0 0.19 1030000.0 -77671.875 -0.444865075401358 -0.2885 -0.5331 2074646 Maybridge2_000158 Cc1cc(C(=O)Nc2cc(ccc2N3CCCC3)C(F)(F)F)n(C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H05 compound treatment 1111200.0 -24200.0 -0.12 1124000.0 -5370.0 -0.03 1129920.0 22248.125 0.12742596732297 -0.0132 -0.0749 2074647 Maybridge2_000159 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc(CNC(=O)c3ccc(Cl)cc3)s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H06 compound treatment 1092870.0 -42600.0 -0.21 1071880.0 -57500.0 -0.34 1011070.0 -96601.875 -0.5532865069343 -0.6369 -0.9327 2074648 Maybridge2_000160 CC(C)(CC(=O)N1CCN(CC1)c2ncccc2C(F)(F)F)Sc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H07 compound treatment 1143360.0 7920.0 0.04 1179590.0 50200.0 0.3 1133220.0 25548.125 0.146326692312865 0.2792 0.834 1269767 Maybridge2_000161 Cc1cc(C(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)c(C)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H08 compound treatment 1114400.0 -21000.0 -0.1 1029720.0 -99600.0 -0.59 1166720.0 59048.125 0.338197688422403 -0.2062 -0.2989 2074649 Maybridge2_000162 CCN(CC)CC(=O)N1c2ccccc2Sc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H09 compound treatment 1153040.0 17600.0 0.09 1313220.0 184000.0 1.09 1087040.0 -20631.875 -0.118168907697238 0.6126 0.5554 1192023 Maybridge2_000163 O=C(N1CCN(CC1)C2c3ccccc3-c4ccccc24)c5ccno5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H10 compound treatment 1113210.0 -22200.0 -0.11 1244800.0 115000.0 0.69 1157510.0 49838.125 0.285447483223333 0.4984 0.6634 2074650 Maybridge2_000164 O=C(CN1CCOCC1)N2c3ccccc3Sc4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H11 compound treatment 1133510.0 -1930.0 -0.01 1054560.0 -74800.0 -0.44 1038420.0 -69251.875 -0.396639589215021 -0.4913 -0.8242 1322755 Maybridge2_000165 Cc1cccc(Cl)c1NC(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H12 compound treatment 1353560.0 218000.0 1.07 1499520.0 370000.0 2.2 1190040.0 82368.125 0.471762811684326 2.1585 0.8666 2074651 Maybridge2_000166 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(Cl)sc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H13 compound treatment 1330850.0 195000.0 0.95 1345920.0 217000.0 1.29 1472600.0 364928.125 2.09012307021301 2.5014 0.9496 2074652 Maybridge2_000167 Clc1cc(C(=O)Nc2ccccc2N3CCCCC3)c(Cl)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H14 compound treatment 1170580.0 35100.0 0.17 1131390.0 2020.0 0.01 1029160.0 -78511.875 -0.44967616903515 -0.1536 -0.3189 2074653 Maybridge2_000168 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2sc3ccccc3c2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H15 compound treatment 1300820.0 165000.0 0.81 1224510.0 95100.0 0.57 1060040.0 -47631.875 -0.272811203069104 0.6356 0.6211 2074654 Maybridge2_000169 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3ccc(s3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H16 compound treatment 1388050.0 253000.0 1.23 1174120.0 44800.0 0.27 1264120.0 156448.125 0.896055450245358 1.3835 0.8936 2074655 Maybridge2_000170 Fc1cccc(c1)S(=O)(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H17 compound treatment 1237520.0 102000.0 0.5 1095130.0 -34200.0 -0.2 1004640.0 -103031.875 -0.590114283202489 -0.1703 -0.2132 2074656 Maybridge2_000171 CN(CCc1ccccn1)C(=O)Nc2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H18 compound treatment 1155540.0 20100.0 0.1 1090330.0 -39000.0 -0.23 1086600.0 -21071.875 -0.120689004362557 -0.147 -0.5261 2074657 Maybridge2_000172 Cc1ccc2cc(NC(=O)C3CN(Cc4ccc(F)cc4)C(=O)C3)ccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H19 compound treatment 1324740.0 189000.0 0.92 1099200.0 -30200.0 -0.18 1064960.0 -42711.875 -0.244631940356897 0.2892 0.2971 2074658 Maybridge2_000173 O=C(N1CCCCC1c2ccccn2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H20 compound treatment 1051150.0 -84300.0 -0.41 1022240.0 -107000.0 -0.64 965170.0 -142501.875 -0.816178409066473 -1.0768 -0.9664 2074659 Maybridge2_000174 CN(C)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H21 compound treatment 1185320.0 49900.0 0.24 1091050.0 -38300.0 -0.23 1236650.0 128978.125 0.738721233435537 0.4356 0.5375 2074660 Maybridge2_000175 Fc1ccc(NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H22 compound treatment 808550.0 -327000.0 -1.6 894590.0 -235000.0 -1.4 829230.0 -278441.875 -1.59477372880171 -2.6489 -0.9981 2074661 Maybridge2_000176 CN(C)c1ccc(NC(=O)c2cccs2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H23 mock treatment 1256260.0 121000.0 0.59 1226720.0 97400.0 0.58 1186280.0 78608.125 0.450227440180688 0.935 0.9931 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 H24 mock treatment 1097550.0 -37900.0 -0.19 1250740.0 121000.0 0.72 1107430.0 -241.875 -0.00138533722937297 0.309 0.4147 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I01 compound treatment 1031100.0 -104000.0 -0.51 1013920.0 -115000.0 -0.69 993710.0 -113961.875 -0.652715775365989 -1.0675 -0.9924 1192854 Maybridge2_000177 CCOC(=O)c1ccc(cc1)N2CC3CCCCN3C2c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I02 compound treatment 1230270.0 94800.0 0.46 1339520.0 210000.0 1.25 1059690.0 -47981.875 -0.274815825416517 0.8303 0.6102 2074662 Maybridge2_000178 CN(C)/C=N/C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I03 compound treatment 1064720.0 -70700.0 -0.35 1089280.0 -40100.0 -0.24 1052340.0 -55331.875 -0.316912894712192 -0.5201 -0.9888 1358017 Maybridge2_000179 CC1CCN(Cc2cc(Cl)c(O)c(Cl)c2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I04 compound treatment 1089820.0 -45600.0 -0.22 1249390.0 120000.0 0.71 1083360.0 -24311.875 -0.139246079807181 0.203 0.2669 2074663 Maybridge2_000180 Fc1ccc(cc1)C2CCCN2S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I05 compound treatment 974640.0 -161000.0 -0.79 1048570.0 -80800.0 -0.48 954320.0 -153351.875 -0.878321701836278 -1.2381 -0.9729 1597589 Maybridge2_000181 CN1C2CCC1CC(C2)NS(=O)(=O)c3cc(Cl)c(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I06 compound treatment 1093380.0 -42100.0 -0.21 994990.0 -134000.0 -0.8 1071620.0 -36051.875 -0.206486840831837 -0.6992 -0.8221 2074664 Maybridge2_000182 CN(C)c1ccc(/C=N/O)c(N(C)C)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I07 compound treatment 1312330.0 177000.0 0.86 1403360.0 274000.0 1.63 1193450.0 85778.125 0.491293560840551 1.7233 0.9029 1410644 Maybridge2_000183 CN1C2CCC1CC(C2)NC(=O)CSc3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I08 compound treatment 1115390.0 -20100.0 -0.1 1176800.0 47400.0 0.28 1217870.0 110198.125 0.631158925765772 0.4707 0.6741 2074665 Maybridge2_000184 CN(C)/C=C/C(=O)c1nnn(c1C)c2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I09 compound treatment 1046850.0 -88600.0 -0.43 1112580.0 -16800.0 -0.1 1079260.0 -28411.875 -0.16272879873402 -0.4015 -0.8487 1455937 Maybridge2_000185 CN1C2CCC1CC(C2)NC(=O)CS(=O)(=O)c3ccc(F)cc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I10 compound treatment 1139520.0 4080.0 0.02 1098080.0 -31300.0 -0.19 1079580.0 -28091.875 -0.160896001159242 -0.1888 -0.7651 2074666 Maybridge2_000186 CN(C)/C=C/C(=O)c1nnn(c1C)c2cc(Cl)ccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I11 compound treatment 1179580.0 44100.0 0.22 1191200.0 61800.0 0.37 1134400.0 26728.125 0.153085133369858 0.4252 0.9387 2074667 Maybridge2_000187 CCCCNC1N=C(c2ccccc2)c3ccccc3N(C)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I12 compound treatment 1140510.0 5070.0 0.02 1170980.0 41600.0 0.25 1064000.0 -43671.875 -0.25013033308123 0.0127 0.0361 2074668 Maybridge2_000188 CN(C)c1cc(oc(=O)c1Cl)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I13 compound treatment 1164400.0 29000.0 0.14 1486740.0 357000.0 2.13 1040640.0 -67031.875 -0.383924556040001 1.087 0.5023 2074669 Maybridge2_000189 Cc1ccc(cc1)S(=O)(=O)N2CCCC(C2)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I14 compound treatment 926920.0 -209000.0 -1.02 886280.0 -243000.0 -1.45 1173850.0 66178.125 0.379034709385418 -1.204 -0.6657 2074670 Maybridge2_000190 CC1CNC(N1)SCc2ccc(C)c(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I15 compound treatment 1100400.0 -35000.0 -0.17 1121730.0 -7640.0 -0.05 1061300.0 -46371.875 -0.265594562618417 -0.2784 -0.8721 1725187 Maybridge2_000191 COC(=O)c1ccc(CN2CCOCC2)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I16 compound treatment 1115560.0 -19900.0 -0.1 143140.0 -986000.0 -5.86 1171060.0 63388.125 0.363055005530325 -3.2324 -0.55 2074671 Maybridge2_000192 COc1cc2CCN(Cc3ccc(F)cc3)C(=O)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I17 compound treatment 1199960.0 64500.0 0.32 1025010.0 -104000.0 -0.62 971810.0 -135861.875 -0.778147859389836 -0.6256 -0.5992 2074672 Maybridge2_000193 CN(C)CCCNS(=O)(=O)c1cc(Cl)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I18 compound treatment 1203920.0 68500.0 0.33 1365930.0 237000.0 1.41 1123390.0 15718.125 0.0900254418126635 1.0573 0.7298 2074673 Maybridge2_000194 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccccc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I19 compound treatment 1022530.0 -113000.0 -0.55 973400.0 -156000.0 -0.93 938120.0 -169551.875 -0.971107079059398 -1.4147 -0.9744 2074674 Maybridge2_000195 CCN(CC)CCNS(=O)(=O)c1c(C)c(C)c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I20 compound treatment 1318780.0 183000.0 0.9 1265950.0 137000.0 0.81 1264360.0 156688.125 0.897430048426441 1.5042 0.999 1562614 Maybridge2_000196 Brc1ccsc1C(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I21 compound treatment 1121370.0 -14100.0 -0.07 1141220.0 11900.0 0.07 1070730.0 -36941.875 -0.211584309086687 -0.1212 -0.5192 2074675 Maybridge2_000197 CN(C)CCCNC(=O)c1cc(Br)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I22 compound treatment 1130240.0 -5200.0 -0.03 1088320.0 -41000.0 -0.24 1184430.0 76758.125 0.439631579201505 0.0982 0.1951 1311571 Maybridge2_000198 CC1(C)CCc2cc(CN3CCN(CC3)c4ccccn4)ccc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I23 mock treatment 1181600.0 46200.0 0.23 1171170.0 41800.0 0.25 1219850.0 112178.125 0.642499360759709 0.6447 0.8893 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 I24 mock treatment 1195100.0 59700.0 0.29 1173410.0 44000.0 0.26 1132960.0 25288.125 0.144837544283358 0.4031 0.9649 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J01 compound treatment 1129950.0 -5490.0 -0.03 1160830.0 31500.0 0.19 1158330.0 50658.125 0.290144027008701 0.26 0.7509 2074676 Maybridge2_000199 Cc1cc(C)cc(c1)N2C(=O)CCN(Cc3ccccc3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J02 compound treatment 941820.0 -194000.0 -0.95 880800.0 -249000.0 -1.48 950180.0 -157491.875 -0.902033520459965 -1.9204 -0.9732 2074677 Maybridge2_000200 Clc1ccc2[nH]c(cc2c1)C(=O)NC3CCN(Cc4ccccc4)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J03 compound treatment 1111010.0 -24400.0 -0.12 1371730.0 242000.0 1.44 1388290.0 280618.125 1.60723818418331 1.6911 0.7822 2074678 Maybridge2_000201 O=C(CN1CCOCC1)Nc2ccccc2Oc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J04 compound treatment 1130340.0 -5100.0 -0.02 1207080.0 77700.0 0.46 1324510.0 216838.125 1.24193871756043 0.9694 0.7315 2074679 Maybridge2_000202 Cc1c(csc1C(=O)Nc2cc(ccc2N3CCCC3)C(F)(F)F)S(=O)(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J05 compound treatment 1154990.0 19500.0 0.1 1254420.0 125000.0 0.74 1122590.0 14918.125 0.0854434478757194 0.5338 0.7074 2074680 Maybridge2_000203 CC(C)N(Cc1ccccc1)C(=O)c2ccc(OC(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J06 compound treatment 1104910.0 -30500.0 -0.15 1129490.0 122.0 0.0 1272040.0 164368.125 0.941417190221105 0.4578 0.4803 2074681 Maybridge2_000204 CC(C)(CC(=O)N1CCN(CC1)c2ccccc2)Sc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J07 compound treatment 1131270.0 -4170.0 -0.02 1124330.0 -5040.0 -0.03 1093440.0 -14231.875 -0.0815129562016844 -0.0761 -0.8534 2074682 Maybridge2_000205 CC1=NCCN1CCNC(=O)Nc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J08 compound treatment 966340.0 -169000.0 -0.83 1035690.0 -93700.0 -0.56 972520.0 -135151.875 -0.774081339770798 -1.2455 -0.9871 2074683 Maybridge2_000206 CN(C)c1ccc(Nc2nc(c(s2)C(=O)c3ccc(F)cc3)c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J09 compound treatment 1192970.0 57500.0 0.28 1350690.0 221000.0 1.32 1327850.0 220178.125 1.26106854224717 1.6502 0.8948 1280598 Maybridge2_000207 Cc1cc(no1)C(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J10 compound treatment 1079250.0 -56200.0 -0.27 1123630.0 -5740.0 -0.03 1079540.0 -28131.875 -0.16112510085609 -0.2712 -0.8472 2074684 Maybridge2_000208 O=C(CN1CCCCC1)N2c3ccccc3Sc4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J11 compound treatment 1083910.0 -51500.0 -0.25 1101120.0 -28200.0 -0.17 1294630.0 186958.125 1.07080124401557 0.3759 0.3378 2074685 Maybridge2_000209 FC(F)(F)Oc1ccccc1NC(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J12 compound treatment 1234940.0 99500.0 0.49 1527590.0 398000.0 2.37 1094570.0 -13101.875 -0.0750408897657508 1.6045 0.6634 2074686 Maybridge2_000210 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J13 compound treatment 1529780.0 394000.0 1.93 1528200.0 399000.0 2.37 1124370.0 16698.125 0.0956383843854202 2.5369 0.8298 2074687 Maybridge2_000211 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccccc3N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J14 compound treatment 1203910.0 68500.0 0.33 1260540.0 131000.0 0.78 1449930.0 342258.125 1.96028081702486 1.7752 0.8311 2074688 Maybridge2_000212 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccsc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J15 compound treatment 1143060.0 7620.0 0.04 1137280.0 7910.0 0.05 1231590.0 123918.125 0.709740121784365 0.4584 0.6436 2074689 Maybridge2_000213 CN1CCN(CC1)C(=O)c2ccc(s2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J16 compound treatment 1143680.0 8240.0 0.04 1149300.0 19900.0 0.12 1182610.0 74938.125 0.429207542994957 0.3395 0.7593 2074690 Maybridge2_000214 FC(F)(F)c1ccc(nc1)N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J17 compound treatment 1148860.0 13400.0 0.07 1535520.0 406000.0 2.42 1196210.0 88538.125 0.507101439923008 1.725 0.6988 1181324 Maybridge2_000215 O=C(Nc1ccccc1)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J18 compound treatment 1281160.0 146000.0 0.71 1373700.0 244000.0 1.45 1376930.0 269258.125 1.5421738702787 2.1403 0.9575 2074691 Maybridge2_000216 Clc1ccc(CCN2CC(CC2=O)C(=O)Nc3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J19 compound treatment 1173600.0 38200.0 0.19 1117350.0 -12000.0 -0.07 1194760.0 87088.125 0.498796575912297 0.3544 0.6595 2074692 Maybridge2_000217 OC(=O)c1ccccc1C(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J20 compound treatment 931720.0 -204000.0 -1.0 841080.0 -288000.0 -1.71 888850.0 -218821.875 -1.25330063065095 -2.288 -0.9756 2074693 Maybridge2_000218 CN(C)c1ccc(NC(=O)Nc2ccc(cc2)C(C)(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J21 compound treatment 1277230.0 142000.0 0.69 1143290.0 13900.0 0.08 1162090.0 54418.125 0.311679398512339 0.6277 0.8215 2074694 Maybridge2_000219 Cc1ccc(F)cc1NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J22 compound treatment 1046310.0 -89100.0 -0.44 1004520.0 -125000.0 -0.74 963040.0 -144631.875 -0.828377967923587 -1.1583 -0.9696 1248737 Maybridge2_000220 CN(C)c1ccc(NC(=O)c2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J23 mock treatment 1218740.0 83300.0 0.41 1320750.0 191000.0 1.14 1190480.0 82808.125 0.474282908349645 1.1659 0.8979 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 J24 mock treatment 1135460.0 16.1 0.0 1170830.0 41500.0 0.25 1171090.0 63418.125 0.363226830302961 0.3521 0.8021 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K01 compound treatment 1112640.0 -22800.0 -0.11 1174790.0 45400.0 0.27 1254720.0 147048.125 0.842217021486263 0.5779 0.6482 1325314 Maybridge2_000221 CN1CCc2ccccc2C1Cc3ccccc3NC(=O)c4c(C)onc4c5ccccc5Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K02 compound treatment 1072320.0 -63100.0 -0.31 1164390.0 35000.0 0.21 1198450.0 90778.125 0.519931022946452 0.2424 0.3791 2074695 Maybridge2_000222 COc1ccc(cc1)C(=O)/C(=C/N(C)C)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K03 compound treatment 1020410.0 -115000.0 -0.56 1046800.0 -82600.0 -0.49 1043450.0 -64221.875 -0.367830302336484 -0.8203 -0.986 2074696 Maybridge2_000223 CN(C)/C=C/1\N=C(OC1=O)c2cccnc2Sc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K04 compound treatment 1151360.0 15900.0 0.08 1209810.0 80400.0 0.48 1159910.0 52238.125 0.299193465034166 0.4938 0.867 2074697 Maybridge2_000224 Cc1cc(cc(C)c1F)S(=O)(=O)N2CCCC2c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K05 compound treatment 1068090.0 -67400.0 -0.33 1117510.0 -11900.0 -0.07 1207010.0 99338.125 0.568958358071755 0.0978 0.1479 1422067 Maybridge2_000225 CN1C2CCC1CC(C2)NS(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K06 compound treatment 1105030.0 -30400.0 -0.15 1025710.0 -104000.0 -0.62 889340.0 -218331.875 -1.25049415936457 -1.1636 -0.83 2074698 Maybridge2_000226 CN(C)/C=N/C(=C(/C#N)\C(=O)C)/SCc1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K07 compound treatment 1191630.0 56200.0 0.27 1148510.0 19100.0 0.11 1101140.0 -6531.875 -0.0374112645585966 0.2026 0.6764 1644872 Maybridge2_000227 CN1C2CCC1CC(C2)NC(=O)CSc3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K08 compound treatment 1024320.0 -111000.0 -0.54 1258490.0 129000.0 0.77 1137210.0 29538.125 0.169179387073374 0.2275 0.2381 2074699 Maybridge2_000228 CN(C)C(=O)N1CCC(CC1)C(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K09 compound treatment 1100050.0 -35400.0 -0.17 1229080.0 99700.0 0.59 1157010.0 49338.125 0.282583737012743 0.4056 0.5972 2074700 Maybridge2_000229 CN1C2CCC1CC(C2)/N=C\c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K10 compound treatment 1265160.0 130000.0 0.63 1195230.0 65900.0 0.39 1326270.0 218598.125 1.25201910422171 1.3149 0.9025 2074701 Maybridge2_000230 Cc1c(C)c(C)c(C(=O)C2CCN(CC2)C(=O)Nc3ccc(Cl)cc3Cl)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K11 compound treatment 1211940.0 76500.0 0.37 1600440.0 471000.0 2.8 1192800.0 85128.125 0.487570690766783 2.1146 0.7373 2074702 Maybridge2_000231 C[C@@H](N1[C@H]2CCC(=O)C[C@@H]2CCC1=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K12 compound treatment 953240.0 -182000.0 -0.89 957970.0 -171000.0 -1.02 886290.0 -221381.875 -1.26796301124917 -1.8345 -0.9892 2074703 Maybridge2_000232 CN(C)/C=C/C(=N)SCc1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K13 compound treatment 1161350.0 25900.0 0.13 1198470.0 69100.0 0.41 1334030.0 226358.125 1.29646444541007 1.0588 0.7752 2074704 Maybridge2_000233 COc1cccc(OC)c1C(=O)Nc2c3c(cc(N4CCCC4)c2C)C(C)(C)CC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K14 compound treatment 664320.0 -471000.0 -2.3 634160.0 -495000.0 -2.94 589210.0 -518461.875 -2.96948645973339 -4.7436 -0.9937 2074705 Maybridge2_000234 CN1CNC(=NC1)SCc2cccc(C#N)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K15 compound treatment 1133190.0 -2250.0 -0.01 1211480.0 82100.0 0.49 1117790.0 10118.125 0.0579514842540542 0.309 0.6283 2074706 Maybridge2_000235 Fc1cccc(Cl)c1NC(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K16 compound treatment 1096220.0 -39200.0 -0.19 1171750.0 42400.0 0.25 1137240.0 29568.125 0.16935121184601 0.1326 0.3694 2074707 Maybridge2_000236 COc1cc2CCN(Cc3c(Cl)cccc3Cl)C(=O)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K17 compound treatment 1060840.0 -74600.0 -0.36 1247680.0 118000.0 0.7 1012490.0 -95181.875 -0.545153467696224 -0.119 -0.1237 2074708 Maybridge2_000237 Clc1c(C#N)ccc(N2CCCC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K18 compound treatment 1179040.0 43600.0 0.21 1339050.0 210000.0 1.25 1162180.0 54508.125 0.312194872830245 1.0231 0.7853 2074709 Maybridge2_000238 Cc1cn(CCC(=O)Nc2ccc(cc2)N3CCOCC3)c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K19 compound treatment 919200.0 -216000.0 -1.06 879720.0 -250000.0 -1.48 1090500.0 -17171.875 -0.0983517839199543 -1.5239 -0.8351 2074710 Maybridge2_000239 FC(F)(F)c1cc(/C=C\c2noc(n2)c3ccc(CN4CCCC4)cc3)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K20 compound treatment 1147770.0 12300.0 0.06 1366910.0 238000.0 1.41 1073770.0 -33901.875 -0.1941727321263 0.7382 0.5173 1138919 Maybridge2_000240 COc1ccc2[nH]c(cc2c1)C(=O)N(C)C3CCN(C)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K21 compound treatment 1116970.0 -18500.0 -0.09 1115520.0 -13800.0 -0.08 1337220.0 229548.125 1.31473514623363 0.6594 0.4994 1707521 Maybridge2_000241 CCN1CCCC1CNC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K22 compound treatment 1101320.0 -34100.0 -0.17 991880.0 -137000.0 -0.82 1191450.0 83778.125 0.47983857599819 -0.2913 -0.3026 1663898 Maybridge2_000242 CC1(C)CCc2cc(CN3CCN(CC3)c4ccc(F)cc4)ccc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K23 mock treatment 1093670.0 -41800.0 -0.2 1199270.0 69900.0 0.42 1105250.0 -2421.875 -0.0138712707075459 0.1141 0.2464 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 K24 mock treatment 1178160.0 42700.0 0.21 1235090.0 106000.0 0.63 1213120.0 105448.125 0.603953336765166 0.8322 0.9283 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L01 compound treatment 1044010.0 -91400.0 -0.45 1059470.0 -69900.0 -0.42 1139200.0 31528.125 0.180577096991523 -0.3936 -0.6186 2074711 Maybridge2_000243 O=C(Nc1ccc2OCCc2c1)N(CCC#N)Cc3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L02 compound treatment 1041870.0 -93600.0 -0.46 1396090.0 267000.0 1.59 1072510.0 -35161.875 -0.201389372576987 0.5355 0.322 2074712 Maybridge2_000244 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cc4cc(Cl)ccc4[nH]3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L03 compound treatment 1125890.0 -9550.0 -0.05 1288330.0 159000.0 0.95 1153330.0 45658.125 0.2615065649028 0.6698 0.6821 1539911 Maybridge2_000245 CN(C1CCN(C)CC1)C(=O)c2cnn(c2C)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L04 compound treatment 1039170.0 -96300.0 -0.47 1126430.0 -2940.0 -0.02 1229810.0 122138.125 0.699545185274664 0.1222 0.145 2074713 Maybridge2_000246 FC(F)(F)c1ccc(N2CCCC2)c(NC(=O)Nc3cccc4ccccc34)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L05 compound treatment 1127290.0 -8150.0 -0.04 1291690.0 162000.0 0.97 1094910.0 -12761.875 -0.0730935423425495 0.4921 0.5079 2074714 Maybridge2_000247 CC(C)N(Cc1ccccc1)C(=O)c2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L06 compound treatment 999570.0 -136000.0 -0.66 1176800.0 47400.0 0.28 1234350.0 126678.125 0.725548000866822 0.1985 0.194 2074715 Maybridge2_000248 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccc4OCCCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L07 compound treatment 1231930.0 96500.0 0.47 1438360.0 309000.0 1.84 1100700.0 -6971.875 -0.0399313612239159 1.31 0.6904 1303662 Maybridge2_000249 COc1ccc(cc1)C(=O)c2c(N)sc3CN(Cc4ccccc4)CCc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L08 compound treatment 1229440.0 94000.0 0.46 1387590.0 258000.0 1.54 1164690.0 57018.125 0.326570878807407 1.3402 0.8194 2074716 Maybridge2_000250 OC(CNCC1COc2ccccc2O1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L09 compound treatment 1150880.0 15400.0 0.08 1159160.0 29800.0 0.18 1104610.0 -3061.875 -0.0175368658571012 0.1357 0.7019 1610217 Maybridge2_000251 Clc1ccc(C(=O)Nc2ccc(cc2)N3CCCCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L10 compound treatment 1026270.0 -109000.0 -0.53 1292430.0 163000.0 0.97 978170.0 -129501.875 -0.74172100759113 -0.1764 -0.1324 2074717 Maybridge2_000252 FC(F)(F)c1ccc(cc1)C(=O)NCCCN2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L11 compound treatment 1199610.0 64200.0 0.31 1489570.0 360000.0 2.14 1070350.0 -37321.875 -0.213760756206736 1.2943 0.595 2074718 Maybridge2_000253 CCc1cccc(C)c1NC(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L12 compound treatment 1077280.0 -58200.0 -0.28 1111380.0 -18000.0 -0.11 1120060.0 12388.125 0.0709528920501334 -0.1849 -0.5928 2074719 Maybridge2_000254 CCOC(=O)N1CCC(CC1)NC(=O)c2sc3ccccc3c2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L13 compound treatment 1259680.0 124000.0 0.61 1422050.0 293000.0 1.74 1321000.0 213328.125 1.22183521916209 2.0607 0.9318 2074720 Maybridge2_000255 O=C(Nc1ccccc1N2CCCCC2)C3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L14 compound treatment 1084640.0 -50800.0 -0.25 1347400.0 218000.0 1.3 1353770.0 246098.125 1.40952514580417 1.419 0.7348 2074721 Maybridge2_000256 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(C)cc(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L15 compound treatment 1118730.0 -16700.0 -0.08 1126880.0 -2490.0 -0.01 1123490.0 15818.125 0.0905981910547816 -0.0034 -0.0275 2074722 Maybridge2_000257 FC(F)(F)Oc1ccc(cc1)C2N(Cc3ccc[nH]3)CCc4sccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L16 compound treatment 1207200.0 71800.0 0.35 1275520.0 146000.0 0.87 1179470.0 71798.125 0.411223216792451 0.9416 0.9201 2074723 Maybridge2_000258 FC(F)(F)c1ccc(cc1)S(=O)(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L17 compound treatment 1217050.0 81600.0 0.4 1388060.0 259000.0 1.54 1087390.0 -20281.875 -0.116164285349825 1.0513 0.6598 2074724 Maybridge2_000259 CC(C)N(Cc1ccccc1)C(=O)c2c(C)onc2c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L18 compound treatment 1134040.0 -1400.0 -0.01 1496880.0 368000.0 2.19 1185280.0 77608.125 0.444499947759508 1.5144 0.6791 2074725 Maybridge2_000260 COc1ccc(NC(=O)C2CN(CCc3ccc(Cl)cc3)C(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L19 compound treatment 1222440.0 87000.0 0.43 1484000.0 355000.0 2.11 1471120.0 363448.125 2.08164638142967 2.6648 0.8902 2074726 Maybridge2_000261 Clc1cccc(NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L20 compound treatment 1042310.0 -93100.0 -0.46 1027680.0 -102000.0 -0.6 1228160.0 120488.125 0.690094822779716 -0.2134 -0.2084 1880074 Maybridge2_000262 CN(C)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L21 compound treatment 1107160.0 -28300.0 -0.14 1294410.0 165000.0 0.98 1179620.0 71948.125 0.412082340655628 0.7248 0.6752 1658667 Maybridge2_000263 O=C(N1CCN(CC1)C(=O)c2ccccc2)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L22 compound treatment 1078760.0 -56700.0 -0.28 1028160.0 -101000.0 -0.6 1059720.0 -47951.875 -0.274644000643882 -0.6659 -0.9286 2074727 Maybridge2_000264 CN(C)c1ccc(NC(=O)c2snnc2C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L23 mock treatment 1071490.0 -64000.0 -0.31 1142260.0 12900.0 0.08 1076710.0 -30961.875 -0.17733390440803 -0.2385 -0.6493 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 L24 mock treatment 1239230.0 104000.0 0.51 1191760.0 62400.0 0.37 1137090.0 29418.125 0.168492087982833 0.6043 0.9289 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M01 compound treatment 1080710.0 -54700.0 -0.27 1036200.0 -93200.0 -0.55 1092320.0 -15351.875 -0.0879277477134063 -0.525 -0.8449 2074728 Maybridge2_000265 C/C=C(\C)/C(=O)Nc1ccccc1CC2N(C)CCc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M02 compound treatment 1182880.0 47400.0 0.23 1111370.0 -18000.0 -0.11 1126210.0 18538.125 0.106176970440392 0.1333 0.4822 2074729 Maybridge2_000266 Fc1cccc(Cl)c1CN(Cc2c(F)cccc2Cl)OC(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M03 compound treatment 1045830.0 -89600.0 -0.44 110280.0 -1020000.0 -6.06 1059410.0 -48261.875 -0.276419523294448 -3.9112 -0.6431 2074730 Maybridge2_000267 CN(C)/C=C/1\N=C(OC1=O)c2cccnc2Sc3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M04 compound treatment 1136590.0 1150.0 0.01 1093920.0 -35400.0 -0.21 1063960.0 -43711.875 -0.250359432778078 -0.263 -0.8035 2074731 Maybridge2_000268 Fc1ccc(cc1)C2CCCN2C(=O)c3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M05 compound treatment 1107930.0 -27500.0 -0.13 1220320.0 91000.0 0.54 1195640.0 87968.125 0.503836769242935 0.5255 0.6995 1449556 Maybridge2_000269 CN1C2CCC1CC(C2)NS(=O)(=O)c3ccc(C#N)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M06 compound treatment 990170.0 -145000.0 -0.71 1177960.0 48600.0 0.29 1267140.0 159468.125 0.913352477357322 0.2844 0.2385 2074732 Maybridge2_000270 CN(C)C(=O)n1cc(C#N)c(n1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M07 compound treatment 894950.0 -240000.0 -1.18 1041230.0 -88100.0 -0.52 1005000.0 -102671.875 -0.588052385930864 -1.3205 -0.9335 1452846 Maybridge2_000271 CN1C2CCC1CC(C2)NC(=O)CSc3ccc(cc3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M08 compound treatment 650090.0 -485000.0 -2.37 631250.0 -498000.0 -2.96 524050.0 -583621.875 -3.3426898658975 -5.0092 -0.9906 2074733 Maybridge2_000272 CN(C)C(=O)ONC(=O)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M09 compound treatment 1060330.0 -75100.0 -0.37 1328510.0 199000.0 1.18 1339090.0 231418.125 1.32544555706124 1.2371 0.6816 1139053 Maybridge2_000273 CN1C2CCC1CC(C2)NCc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M10 compound treatment 1144760.0 9320.0 0.05 1427650.0 298000.0 1.77 1424910.0 317238.125 1.81697895664693 2.0994 0.8267 2074734 Maybridge2_000274 CNC(=O)N1CCC(CC1)C(=O)c2c(C)c(C)c(C)c(C)c2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M11 compound treatment 1190400.0 55000.0 0.27 1382240.0 253000.0 1.5 1439700.0 332028.125 1.90168856955618 2.1211 0.8696 1631500 Maybridge2_000275 CC1C(OCCN1Cc2c(C)c(C)c(C)c(C)c2C)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M12 compound treatment 858920.0 -277000.0 -1.35 901070.0 -228000.0 -1.36 833410.0 -274261.875 -1.57083281048118 -2.4708 -0.9974 2074735 Maybridge2_000276 CN(C)/C=C/C(=N)SCc1c(F)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M13 compound treatment 934450.0 -201000.0 -0.98 1149660.0 20300.0 0.12 1210420.0 102748.125 0.588489107227979 -0.1575 -0.1368 2074736 Maybridge2_000277 FC(F)(F)c1cc(C#CCN2CCCC2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M14 compound treatment 973520.0 -162000.0 -0.79 1240180.0 111000.0 0.66 1072040.0 -35631.875 -0.204081294014941 -0.1941 -0.185 1466440 Maybridge2_000278 Clc1cccc(c1)C(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M15 compound treatment 1057560.0 -77900.0 -0.38 1205830.0 76500.0 0.45 1146370.0 38698.125 0.221643217651385 0.1708 0.2698 2074737 Maybridge2_000279 Fc1cccc(Cl)c1NC(=O)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M16 compound treatment 1096420.0 -39000.0 -0.19 1391430.0 262000.0 1.56 1337320.0 229648.125 1.31530789547575 1.549 0.7563 2074738 Maybridge2_000280 COc1cc2CCN(Cc3cccc(Cl)c3)C(=O)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M17 compound treatment 1094880.0 -40600.0 -0.2 1277280.0 148000.0 0.88 1412480.0 304808.125 1.74578622585166 1.4013 0.7132 2074739 Maybridge2_000281 FC(F)(F)c1cccc(CN(Cc2cccc(c2)C(F)(F)F)OC(=O)c3ccc(Cl)cc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M18 compound treatment 1082830.0 -52600.0 -0.26 1157890.0 28500.0 0.17 1185950.0 78278.125 0.448337367681699 0.2084 0.3831 1568873 Maybridge2_000282 Fc1ccc(NC(=O)N2CCN(Cc3ccccc3)CC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M19 compound treatment 1041680.0 -93800.0 -0.46 1235630.0 106000.0 0.63 1182790.0 75118.125 0.430238491630769 0.3487 0.3913 2074740 Maybridge2_000283 FC(F)(F)c1cc(/C=C\c2noc(n2)c3ccccc3CN4CCCC4)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M20 compound treatment 1114300.0 -21100.0 -0.1 1266400.0 137000.0 0.81 1173250.0 65578.125 0.37559821393271 0.6277 0.6949 1236024 Maybridge2_000284 CN(C1CCN(C)CC1)C(=O)c2cnn(c2C)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M21 compound treatment 1058210.0 -77200.0 -0.38 1152490.0 23100.0 0.14 1222130.0 114458.125 0.65555804348 0.24 0.3122 2074741 Maybridge2_000285 CN(C)C(=O)Oc1ccc(Br)cc1C(=O)Nc2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M22 compound treatment 1026210.0 -109000.0 -0.53 1147970.0 18600.0 0.11 1018170.0 -89501.875 -0.51262131074392 -0.5402 -0.722 2074742 Maybridge2_000286 O=C(Nc1ccc(OCc2ccccc2)cc1)Oc3ccccc3N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M23 mock treatment 1030590.0 -105000.0 -0.51 1162270.0 32900.0 0.2 1298910.0 191238.125 1.09531491157822 0.4496 0.367 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 M24 mock treatment 1089520.0 -45900.0 -0.22 1125530.0 -3840.0 -0.02 1108380.0 708.125 0.00405578057074825 -0.1404 -0.6223 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N01 compound treatment 827270.0 -308000.0 -1.51 886520.0 -243000.0 -1.44 1038760.0 -68911.875 -0.39469224179182 -1.9309 -0.9094 2074743 Maybridge2_000287 CC(C)(C)c1ccc(NC(=O)N(CCC#N)CCc2ccccn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N02 compound treatment 894340.0 -241000.0 -1.18 971120.0 -158000.0 -0.94 682720.0 -424951.875 -2.43390864342883 -2.6286 -0.9181 2074744 Maybridge2_000288 FC(F)(F)c1ccc(N2CCCC2)c(NC(=O)Nc3ccc(OCc4ccccc4)cc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N03 compound treatment 1191260.0 55800.0 0.27 1240500.0 111000.0 0.66 1308240.0 200568.125 1.14875241586783 1.2022 0.8885 2074745 Maybridge2_000289 CC(C)N(Cc1ccccc1)C(=O)c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N04 compound treatment 1120160.0 -15300.0 -0.07 1433810.0 304000.0 1.81 1387810.0 280138.125 1.60448898782114 1.9285 0.7968 2074746 Maybridge2_000290 OC(=O)CCC(=O)Nc1cc(ccc1N2CCCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N05 compound treatment 1199160.0 63700.0 0.31 1382790.0 253000.0 1.51 1269060.0 161388.125 0.924349262805988 1.5835 0.8821 2074747 Maybridge2_000291 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc(s2)S(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N06 compound treatment 1056560.0 -78900.0 -0.39 1197690.0 68300.0 0.41 1132000.0 24328.125 0.139339151559025 0.0925 0.1603 2074748 Maybridge2_000292 O=S(=O)(NCc1ccc(cc1)N2CCOCC2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N07 compound treatment 1122800.0 -12600.0 -0.06 1479780.0 350000.0 2.08 1367420.0 259748.125 1.48770541735328 2.0263 0.7912 1121411 Maybridge2_000293 COc1ccc(cc1)C(=O)c2c(N)sc3CN(C)CCc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N08 compound treatment 1057810.0 -77600.0 -0.38 1304670.0 175000.0 1.04 1164580.0 56908.125 0.325940854641077 0.571 0.4939 2074749 Maybridge2_000294 O=S1(=O)CCN(CC2COc3ccccc3O2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N09 compound treatment 1226080.0 90600.0 0.44 1224030.0 94700.0 0.56 1240080.0 132408.125 0.758366532440185 1.0185 0.9764 1198415 Maybridge2_000295 Clc1ccc(cc1)C(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N10 compound treatment 991150.0 -144000.0 -0.7 1286340.0 157000.0 0.93 1117220.0 9548.125 0.0546868135739815 0.1635 0.1396 2074750 Maybridge2_000296 FC(F)(F)c1cccnc1N2CCN(Cc3ccc[nH]3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N11 compound treatment 1104040.0 -31400.0 -0.15 1395520.0 266000.0 1.58 1293070.0 185398.125 1.06186635583853 1.4383 0.7522 1511787 Maybridge2_000297 O=S(=O)(Nc1ccc(cc1)N2CCCCC2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N12 compound treatment 1184260.0 48800.0 0.24 1362970.0 234000.0 1.39 1215880.0 108208.125 0.619761215847623 1.2975 0.8427 2074751 Maybridge2_000298 Cc1ccc(C)n1CC2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N13 compound treatment 1260000.0 125000.0 0.61 1469380.0 340000.0 2.02 1384030.0 276358.125 1.58283906646908 2.4326 0.9218 1861731 Maybridge2_000299 Cc1ccc(cc1)C(=O)Nc2ccccc2N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N14 compound treatment 1141830.0 6390.0 0.03 1387040.0 258000.0 1.53 1376480.0 268808.125 1.53959649868917 1.7916 0.8247 2074752 Maybridge2_000300 Fc1ccc(NC(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N15 compound treatment 885380.0 -250000.0 -1.22 1113340.0 -16000.0 -0.1 968400.0 -139271.875 -0.797678608546061 -1.221 -0.835 2074753 Maybridge2_000301 FC(F)(F)Oc1ccc(cc1)C2N(Cc3c[nH]c4ccccc34)CCc5sccc25 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N16 compound treatment 1233450.0 98000.0 0.48 1357190.0 228000.0 1.35 1217540.0 109868.125 0.629268853266782 1.4219 0.9065 2074754 Maybridge2_000302 Clc1c(sc2ccccc12)C(=O)N3CCN(CC3)C(=O)C4CCCO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N17 compound treatment 1075070.0 -60400.0 -0.29 1184330.0 55000.0 0.33 1213360.0 105688.125 0.605327934946249 0.3679 0.4915 2074755 Maybridge2_000303 CC(C)N(Cc1ccccc1)C(=O)c2ccc3nsnc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N18 compound treatment 1134130.0 -1310.0 -0.01 1300680.0 171000.0 1.02 1428160.0 320488.125 1.83559330701576 1.6442 0.7832 2074756 Maybridge2_000304 Cc1ccc(NC(=O)C2CN(CCc3ccc(Cl)cc3)C(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N19 compound treatment 1288070.0 153000.0 0.75 1385830.0 256000.0 1.53 1343740.0 236068.125 1.35207839681973 2.0917 0.9638 2074757 Maybridge2_000305 FC(F)(F)c1cccc(NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N20 compound treatment 880030.0 -255000.0 -1.25 894560.0 -235000.0 -1.4 911040.0 -196631.875 -1.12620757382496 -2.1768 -0.9962 2074758 Maybridge2_000306 CN(C)c1ccc(NC(=O)Nc2ccccc2F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N21 compound treatment 729600.0 -406000.0 -1.98 790170.0 -339000.0 -2.02 892000.0 -215671.875 -1.23525902952423 -3.0225 -0.9793 2074759 Maybridge2_000307 C1Cc2c([nH]c3ccccc23)C4(CCNCC4)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N22 compound treatment 1000700.0 -135000.0 -0.66 1192580.0 63200.0 0.38 1183450.0 75778.125 0.434018636628748 0.0875 0.1002 2074760 Maybridge2_000308 CN(C)c1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N23 mock treatment 1158910.0 23500.0 0.11 1313570.0 184000.0 1.1 1189130.0 81458.125 0.466550793581052 0.968 0.8093 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 N24 mock treatment 1066310.0 -69100.0 -0.34 1135330.0 5960.0 0.04 1191730.0 84058.125 0.481442273876121 0.1034 0.1755 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O01 compound treatment 902000.0 -233000.0 -1.14 928100.0 -201000.0 -1.2 1022440.0 -85231.875 -0.488164918105481 -1.6314 -0.9463 1510389 Maybridge2_000309 CN1CCc2ccccc2C1Cc3ccccc3NS(=O)(=O)c4cc(Cl)c(Cl)cc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O02 compound treatment 1113780.0 -21700.0 -0.11 1182950.0 53600.0 0.32 1259970.0 152298.125 0.87228635669746 0.6265 0.6703 2074761 Maybridge2_000310 Clc1ccc(C(=O)NC(=N)N2CCCC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O03 compound treatment 1204180.0 68700.0 0.34 1294680.0 165000.0 0.98 1153690.0 46018.125 0.263568462174425 0.9136 0.8525 2074762 Maybridge2_000311 CN1C2CCC1CC(C2)NC(=O)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O04 compound treatment 1239680.0 104000.0 0.51 1384480.0 255000.0 1.52 1388560.0 280888.125 1.60878460713703 2.0987 0.9249 2074763 Maybridge2_000312 Clc1ccc(Oc2ccccc2S(=O)(=O)N3CCSCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O05 compound treatment 1147140.0 11700.0 0.06 1085620.0 -43700.0 -0.26 1161130.0 53458.125 0.306181005788006 0.0596 0.1468 2074764 Maybridge2_000313 CN1C2CCC1CC(C2)NS(=O)(=O)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O06 compound treatment 1044860.0 -90600.0 -0.44 1317780.0 188000.0 1.12 1290080.0 182408.125 1.0447411534992 0.9945 0.6237 2074765 Maybridge2_000314 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O07 compound treatment 1161170.0 25700.0 0.13 1265980.0 137000.0 0.81 1290810.0 183138.125 1.04892222296666 1.1472 0.8608 1582773 Maybridge2_000315 CN1C2CCC1CC(C2)NC(=O)CSc3ccc(F)cc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O08 compound treatment 1115920.0 -19500.0 -0.1 1173360.0 44000.0 0.26 1239650.0 131978.125 0.755903710699077 0.5324 0.6609 2074766 Maybridge2_000316 Clc1cc(NC(=O)N2CCOCC2)c(Cl)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O09 compound treatment 1088060.0 -47400.0 -0.23 1293800.0 164000.0 0.98 1370890.0 263218.125 1.50757981605477 1.3013 0.7182 2074767 Maybridge2_000317 CN1C2CCC1CC(C2)/N=C\c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O10 compound treatment 1059400.0 -76000.0 -0.37 1346580.0 217000.0 1.29 1155840.0 48168.125 0.275882570879962 0.6905 0.5033 2074768 Maybridge2_000318 NC(=S)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O11 compound treatment 1029470.0 -106000.0 -0.52 1251040.0 122000.0 0.72 1271250.0 163578.125 0.936892471208373 0.6597 0.5106 1446135 Maybridge2_000319 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc(F)c(F)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O12 compound treatment 1151730.0 16300.0 0.08 1260930.0 132000.0 0.78 1273880.0 166208.125 0.951955776276077 1.0472 0.8481 2074769 Maybridge2_000320 CN(C)/C=C/C(=O)c1ccc(cc1)S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O13 compound treatment 1049240.0 -86200.0 -0.42 1157500.0 28100.0 0.17 1193890.0 86218.125 0.49381365750587 0.1385 0.2067 1328314 Maybridge2_000321 Cc1ccc2oc(=O)cc(CN3CCOCC3)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O14 compound treatment 949120.0 -186000.0 -0.91 1000260.0 -129000.0 -0.77 1106030.0 -1641.875 -0.00940382661902529 -0.9743 -0.8181 2074770 Maybridge2_000322 C1CN2CCC1C3=NNC(C23)c4ccc(cc4)c5ccccc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O15 compound treatment 1061660.0 -73800.0 -0.36 1193320.0 64000.0 0.38 1146130.0 38458.125 0.220268619470302 0.1386 0.2438 2074771 Maybridge2_000323 Cc1onc(c1C(=O)N2CCC=CC2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O16 compound treatment 1271130.0 136000.0 0.66 1319870.0 191000.0 1.13 1228230.0 120558.125 0.690495747249199 1.4354 0.9679 2074772 Maybridge2_000324 COc1cc2CCN(Cc3ccc(C)cc3)C(=O)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O17 compound treatment 1046080.0 -89400.0 -0.44 1295200.0 166000.0 0.99 1112010.0 4338.125 0.0248465780596325 0.3316 0.3074 2074773 Maybridge2_000325 CN(C)c1ccc(NC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O18 compound treatment 1192210.0 56800.0 0.28 1272380.0 143000.0 0.85 1163960.0 56288.125 0.322389809339946 0.8373 0.8805 1284206 Maybridge2_000326 Fc1ccc(NC(=O)N2CCN(Cc3ccccc3)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O19 compound treatment 1040880.0 -94600.0 -0.46 1058990.0 -70400.0 -0.42 1344250.0 236578.125 1.35499941795453 0.2739 0.1837 2074774 Maybridge2_000327 CS/C(=N/c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O20 compound treatment 1173440.0 38000.0 0.19 1184650.0 55300.0 0.33 1145240.0 37568.125 0.215171151215452 0.4212 0.9693 2074775 Maybridge2_000328 Brc1ccsc1C(=O)Oc2ccccc2N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O21 compound treatment 1068550.0 -66900.0 -0.33 1141310.0 11900.0 0.07 1243200.0 135528.125 0.776236308794267 0.3005 0.3555 2074776 Maybridge2_000329 CCN(CC)C(=O)Oc1ccc(Br)cc1C(=O)Nc2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O22 compound treatment 918920.0 -217000.0 -1.06 1034920.0 -94400.0 -0.56 927970.0 -179701.875 -1.02924112713438 -1.5293 -0.9684 2074777 Maybridge2_000330 CC(C)(C)c1ccc(NC(=O)Oc2ccccc2N3CCOCC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O23 mock treatment 1126840.0 -8600.0 -0.04 1223930.0 94600.0 0.56 1226570.0 118898.125 0.68098810983004 0.6936 0.7844 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 O24 mock treatment 929710.0 -206000.0 -1.01 936930.0 -192000.0 -1.14 1029820.0 -77851.875 -0.445896024037171 -1.4985 -0.9442 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P01 compound treatment 771950.0 -363000.0 -1.78 827250.0 -302000.0 -1.8 763230.0 -344441.875 -1.97278822859961 -3.2016 -0.9989 1443960 Maybridge2_000331 Fc1ccc(cc1)N2CCN(Cc3c[nH]c4ccccc34)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P02 compound treatment 1075950.0 -59500.0 -0.29 949280.0 -180000.0 -1.07 1082280.0 -25391.875 -0.145431771622056 -0.8701 -0.7774 2074778 Maybridge2_000332 FC(F)(F)c1ccc(N2CCCC2)c(NC(=O)Nc3cccs3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P03 compound treatment 788610.0 -347000.0 -1.69 864350.0 -265000.0 -1.58 806100.0 -301571.875 -1.72725062850361 -2.8855 -0.9992 2074779 Maybridge2_000333 O=C(NC1CCN(Cc2ccccc2)CC1)Nc3csc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P04 compound treatment 1127360.0 -8080.0 -0.04 1143250.0 13900.0 0.08 1154940.0 47268.125 0.2707278277009 0.1812 0.6339 2074780 Maybridge2_000334 OC(=O)c1ccccc1C(=O)Nc2cc(ccc2N3CCCC3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P05 compound treatment 1053570.0 -81900.0 -0.4 1011270.0 -118000.0 -0.7 1145480.0 37808.125 0.216545749396535 -0.5114 -0.6112 2074781 Maybridge2_000335 CC(C)N(Cc1ccccc1)S(=O)(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P06 compound treatment 1073760.0 -61700.0 -0.3 1177200.0 47800.0 0.28 1270050.0 162378.125 0.930019480302956 0.5272 0.5178 2074782 Maybridge2_000336 OC(=O)CCCC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P07 compound treatment 996450.0 -139000.0 -0.68 1196370.0 67000.0 0.4 1126080.0 18408.125 0.105432396425638 -0.1012 -0.1274 1511990 Maybridge2_000337 Nc1sc2CN(Cc3ccccc3)CCc2c1C(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P08 compound treatment 1200560.0 65100.0 0.32 1306350.0 177000.0 1.05 1127680.0 20008.125 0.114596384299527 0.8575 0.7757 2074783 Maybridge2_000338 Cc1ccc(cc1)C2Nc3ccccc3C(=O)N2CCCN4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P09 compound treatment 1072670.0 -62800.0 -0.31 1072960.0 -56400.0 -0.34 1105140.0 -2531.875 -0.0145012948738757 -0.3791 -0.8337 2074784 Maybridge2_000339 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P10 compound treatment 1017440.0 -118000.0 -0.58 1082610.0 -46800.0 -0.28 1260060.0 152388.125 0.872801831015366 0.0105 0.0097 1361938 Maybridge2_000340 CCN(CC)c1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P11 compound treatment 1003170.0 -132000.0 -0.65 1125330.0 -4040.0 -0.02 1074110.0 -33561.875 -0.192225384703098 -0.498 -0.7381 1735126 Maybridge2_000341 Fc1ccccc1S(=O)(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P12 compound treatment 1135680.0 236.0 0.0 1144120.0 14800.0 0.09 1110740.0 3068.125 0.0175726626847336 0.0615 0.6869 1553691 Maybridge2_000342 O=C(N1CCCC1)c2ccc(cc2)C(=O)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P13 compound treatment 1153280.0 17800.0 0.09 1195210.0 65800.0 0.39 1368170.0 260498.125 1.49200103666916 1.1378 0.7364 1861719 Maybridge2_000343 Clc1c(sc2ccccc12)C(=O)Nc3ccccc3N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P14 compound treatment 995560.0 -140000.0 -0.68 1172900.0 43500.0 0.26 1194920.0 87248.125 0.499712974699686 0.0434 0.049 2074785 Maybridge2_000344 Fc1ccc(NC(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P15 compound treatment 1063440.0 -72000.0 -0.35 978650.0 -151000.0 -0.9 1187170.0 79498.125 0.455324908435539 -0.4577 -0.4297 2074786 Maybridge2_000345 OC(=O)c1cc(ccc1N2CCOCC2)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P16 compound treatment 1152000.0 16600.0 0.08 1183040.0 53700.0 0.32 1137630.0 29958.125 0.17158493389027 0.33 0.8889 2074787 Maybridge2_000346 OC(=O)C1CN(C2Cc3ccccc3C2)C(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P17 compound treatment 1070260.0 -65200.0 -0.32 1131290.0 1920.0 0.01 1316930.0 209258.125 1.19852432500789 0.5147 0.415 2074788 Maybridge2_000347 CN(C1CCCCC1)C(=O)c2cc(C)on2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P18 compound treatment 1100180.0 -35300.0 -0.17 1258670.0 129000.0 0.77 1171960.0 64288.125 0.368209748709387 0.557 0.6405 2074789 Maybridge2_000348 Cc1ccc2cc(NC(=O)C3CN(CCc4ccc(Cl)cc4)C(=O)C3)ccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P19 compound treatment 1081290.0 -54200.0 -0.26 1154140.0 24800.0 0.15 1321920.0 214248.125 1.22710451218958 0.6408 0.507 2074790 Maybridge2_000349 Cc1ccc(NC(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P20 compound treatment 937880.0 -198000.0 -0.97 1028590.0 -101000.0 -0.6 983960.0 -123711.875 -0.708558826472496 -1.3124 -0.9801 2074791 Maybridge2_000350 CN(C)c1ccc(NC(=O)Nc2cc(C)cc(C)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P21 compound treatment 1086530.0 -48900.0 -0.24 996500.0 -133000.0 -0.79 1129870.0 22198.125 0.127139592701911 -0.5207 -0.6235 2074792 Maybridge2_000351 Clc1cccc(c1)S(=O)(=O)Nc2ccc(cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P22 compound treatment 1126950.0 -8490.0 -0.04 1100120.0 -29200.0 -0.17 966660.0 -141011.875 -0.807644445358914 -0.5907 -0.7141 1219896 Maybridge2_000352 Cc1ccc(CN2CCS(=O)(=O)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P23 mock treatment 1049380.0 -86100.0 -0.42 1058600.0 -70800.0 -0.42 1076360.0 -31311.875 -0.179338526755443 -0.5893 -0.9484 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1303 P24 mock treatment 916400.0 -219000.0 -1.07 820840.0 -309000.0 -1.83 915890.0 -191781.875 -1.09842923558223 -2.3113 -0.9666 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A01 compound treatment 926050.0 -130000.0 -0.63 839520.0 -209000.0 -1.24 883220.0 -180864.83870968 -1.03590199296768 -1.6828 -0.9676 2074793 Maybridge2_000353 Cc1ccc(NC(=O)C2CN(Cc3ccco3)C(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A02 compound treatment 724860.0 -331000.0 -1.62 727490.0 -321000.0 -1.91 690760.0 -373324.83870968 -2.13821518434802 -3.2714 -0.9937 1173073 Maybridge2_000354 CN(C)CCNc1cc(nc2ccccc12)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A03 compound treatment 931210.0 -125000.0 -0.61 951840.0 -97000.0 -0.58 884680.0 -179404.83870968 -1.02753985403275 -1.2778 -0.9634 1014318 Maybridge2_000355 OC(=O)CN(Cc1ccccc1)Cc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A04 compound treatment 879200.0 -177000.0 -0.86 865930.0 -183000.0 -1.09 857970.0 -206114.83870968 -1.18052117660248 -1.8078 -0.9919 2074794 Maybridge2_000356 CS/C(=C(/C#N)\S(=O)(=O)c1ccc(Cl)cc1)/N2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A05 compound treatment 1059710.0 3870.0 0.02 1043490.0 -5330.0 -0.03 988260.0 -75824.8387096799 -0.434286189046905 -0.2581 -0.5922 2074795 Maybridge2_000357 Fc1cn(C2CCCO2)c(=O)n(Cc3cccc4ccccc34)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A06 compound treatment 863040.0 -193000.0 -0.94 841820.0 -207000.0 -1.23 870610.0 -193474.83870968 -1.10812567239876 -1.8943 -0.9942 1411803 Maybridge2_000358 S=C1SC(CC(=C1)N2CCCCC2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A07 compound treatment 1044680.0 -11200.0 -0.05 960960.0 -87900.0 -0.52 821050.0 -243034.83870968 -1.39198019679245 -1.1368 -0.7641 2074796 Maybridge2_000359 Cc1cc(C)c(C#N)c(n1)N2CCN(CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A08 compound treatment 1124120.0 68300.0 0.33 1074250.0 25400.0 0.15 879590.0 -184494.83870968 -1.05669279045656 -0.3302 -0.2952 1585551 Maybridge2_000360 Cc1ccc(SC2CN(C2)C(c3ccccc3)c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A09 compound treatment 1004510.0 -51300.0 -0.25 1001410.0 -47400.0 -0.28 978270.0 -85814.8387096799 -0.491503838334496 -0.5913 -0.9543 1016614 Maybridge2_000361 CN(C)c1ccc(cc1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A10 compound treatment 711290.0 -345000.0 -1.68 747290.0 -302000.0 -1.79 677170.0 -386914.83870968 -2.21605180635186 -3.2866 -0.9928 2074797 Maybridge2_000362 Cc1nc2c(N3CCOCC3)c(Cl)c(Cl)c(Cl)c2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A11 compound treatment 984100.0 -71700.0 -0.35 991520.0 -57300.0 -0.34 923220.0 -140864.83870968 -0.806802296120467 -0.8649 -0.9169 2074798 Maybridge2_000363 Clc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)CN5CCOCC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A12 compound treatment 1036960.0 -18900.0 -0.09 1018690.0 -30100.0 -0.18 838780.0 -225304.83870968 -1.29043175616493 -0.9017 -0.6904 1360824 Maybridge2_000364 COC(=O)C1CSC(=CC1N(C)C)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A13 compound treatment 1006840.0 -49000.0 -0.24 1007680.0 -41100.0 -0.24 909220.0 -154864.83870968 -0.886987190016991 -0.7916 -0.8326 2074799 Maybridge2_000365 C1CCN(C1)c2nnc(c3ccccc3)c(n2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A14 compound treatment 878800.0 -177000.0 -0.86 893860.0 -155000.0 -0.92 807380.0 -256704.83870968 -1.47027501818999 -1.8803 -0.9698 2074800 Maybridge2_000366 O=C/1Nc2ccccc2\C1=N\C3CCN(Cc4ccccc4)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A15 compound treatment 1046160.0 -9680.0 -0.05 1047200.0 -1620.0 -0.01 857250.0 -206834.83870968 -1.18464497114573 -0.7168 -0.6046 2074801 Maybridge2_000367 Cc1sc(NC(=O)CN2CCN(CC2)c3ccccc3)c(C#N)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A16 compound treatment 1023800.0 -32000.0 -0.16 978130.0 -70700.0 -0.42 996330.0 -67754.8387096799 -0.388065325207981 -0.5571 -0.9393 2074802 Maybridge2_000368 COc1c(Cl)cc(Cl)c(OC)c1C(=O)N2CC(C)OC(C)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A17 compound treatment 986090.0 -69800.0 -0.34 947590.0 -101000.0 -0.6 792660.0 -271424.83870968 -1.55458370662976 -1.4418 -0.8474 2074803 Maybridge2_000369 O=C(Cn1cnc2sc(cc2c1=O)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A18 compound treatment 1098670.0 42800.0 0.21 1105410.0 56600.0 0.34 978110.0 -85974.8387096799 -0.492420237121884 0.0308 0.0487 2074804 Maybridge2_000370 CC(=O)Cn1cc(Cl)c(=O)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A19 compound treatment 786410.0 -269000.0 -1.32 935270.0 -114000.0 -0.68 841320.0 -222764.83870968 -1.27588392541513 -1.8865 -0.9656 2074805 Maybridge2_000371 CC(=O)c1sc2nsc(SCCN3CCCC3)c2c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A20 compound treatment 1071810.0 16000.0 0.08 948670.0 -100000.0 -0.6 865870.0 -198214.83870968 -1.13527398647515 -0.9543 -0.743 2074806 Maybridge2_000372 COc1cc(c(cn1)C(=O)N(C)Cc2ccccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A21 compound treatment 799370.0 -256000.0 -1.25 779750.0 -269000.0 -1.6 676120.0 -387964.83870968 -2.2220656733941 -2.9302 -0.9731 2074807 Maybridge2_000373 CCOC(=O)c1cc(sc1NC(=O)CN2CCCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A22 compound treatment 862130.0 -194000.0 -0.95 883360.0 -165000.0 -0.98 847260.0 -216824.83870968 -1.24186262043332 -1.8315 -0.9924 2074808 Maybridge2_000374 CCSc1cc(c(cn1)C(=O)N(C)Cc2c(OC)cccc2OC)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A23 mock treatment 974090.0 -81800.0 -0.4 943370.0 -105000.0 -0.63 947470.0 -116614.83870968 -0.667910604906847 -0.9783 -0.9788 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 A24 mock treatment 896810.0 -159000.0 -0.78 941290.0 -108000.0 -0.64 844020.0 -220064.83870968 -1.26041969587794 -1.5455 -0.9582 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B01 compound treatment 1050580.0 -5260.0 -0.03 1075890.0 27100.0 0.16 959800.0 -104284.83870968 -0.597290623353695 -0.2668 -0.4308 2074809 Maybridge2_000375 CC(C)N(C(C)C)C1N=C(c2ccccc2)c3cc(Cl)ccc3N(C)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B02 compound treatment 822350.0 -233000.0 -1.14 826560.0 -222000.0 -1.32 735200.0 -328884.83870968 -1.88368542115077 -2.5093 -0.977 2074810 Maybridge2_000376 Clc1cccc(NC(=O)OC2CN3CCC2CC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B03 compound treatment 1140200.0 84400.0 0.41 1167010.0 118000.0 0.7 1019810.0 -44274.8387096799 -0.253583803158669 0.4973 0.5828 1238984 Maybridge2_000377 Clc1ccc(C(=O)N2CCN(Cc3ccccc3)CC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B04 compound treatment 995840.0 -60000.0 -0.29 946570.0 -102000.0 -0.61 1018090.0 -45994.8387096799 -0.263435090123099 -0.6724 -0.928 2074811 Maybridge2_000378 OC(=O)CC1(CC(=O)Nc2ccc(cc2)N3CCCCC3)CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B05 compound treatment 1068880.0 13000.0 0.06 1026570.0 -22300.0 -0.13 903520.0 -160564.83870968 -0.919633896817718 -0.5706 -0.6127 2074812 Maybridge2_000379 CCCc1c(C)nc(SCc2c(F)cccc2Cl)nc1OC(=O)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B06 compound treatment 1070980.0 15100.0 0.07 1055200.0 6380.0 0.04 945610.0 -118474.83870968 -0.678563740810242 -0.3272 -0.4786 2074813 Maybridge2_000380 Fc1ccc(cc1)S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B07 compound treatment 1099590.0 43700.0 0.21 1114680.0 65900.0 0.39 872910.0 -191174.83870968 -1.09495243983005 -0.2827 -0.2391 2074814 Maybridge2_000381 Clc1ccc(Cn2nnc(n2)N3CCCC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B08 compound treatment 1118520.0 62700.0 0.31 1015200.0 -33600.0 -0.2 892120.0 -171964.83870968 -0.984927310419173 -0.5073 -0.4828 2074815 Maybridge2_000382 O=C(N1CCC(=CC1)c2ccccc2)c3csc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B09 compound treatment 1073080.0 17200.0 0.08 1064800.0 16000.0 0.1 916590.0 -147494.83870968 -0.844775570872892 -0.3842 -0.4498 2074816 Maybridge2_000383 CN(C)C(=O)Oc1nc(nc(C)c1C)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B10 compound treatment 1090910.0 35100.0 0.17 1052430.0 3610.0 0.02 923360.0 -140724.83870968 -0.806000447181502 -0.354 -0.4295 2074817 Maybridge2_000384 O=S(=O)(N1CCC(=CC1)c2ccccc2)c3ccsc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B11 compound treatment 1049340.0 -6500.0 -0.03 1014000.0 -34800.0 -0.21 912530.0 -151554.83870968 -0.868029190102884 -0.639 -0.7157 2074818 Maybridge2_000385 CC(=O)N1C(CSC1c2cccs2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B12 compound treatment 1009690.0 -46200.0 -0.23 951060.0 -97800.0 -0.58 1023090.0 -40994.8387096799 -0.234797628017198 -0.6014 -0.9026 2074819 Maybridge2_000386 Cc1ccc(C)n1CCN2CCN(CC2)S(=O)(=O)Cc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B13 compound treatment 38450.0 -1020000.0 -4.97 34490.0 -1010000.0 -6.03 36730.0 -1027354.83870968 -5.88416705257253 -9.7496 -0.9965 2071084 Maybridge2_000387 CN1C/C(=C\c2ccccc2)/C(=O)\C(=C\c3ccccc3)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B14 compound treatment 745920.0 -310000.0 -1.51 673250.0 -376000.0 -2.23 663520.0 -400564.83870968 -2.29423207790097 -3.4882 -0.9849 2074820 Maybridge2_000388 CN1CCN(CC1)c2ccc(NC(=O)c3cccc4CC(C)(C)Oc43)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B15 compound treatment 1045060.0 -10800.0 -0.05 997370.0 -51500.0 -0.31 887560.0 -176524.83870968 -1.01104467585975 -0.7908 -0.7477 2074821 Maybridge2_000389 CC1C(N2CCCCC2)C(=O)N(C1=O)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B16 compound treatment 1035400.0 -20400.0 -0.1 1018520.0 -30300.0 -0.18 978080.0 -86004.8387096799 -0.49259206189452 -0.4461 -0.8355 2074822 Maybridge2_000390 Fc1cc(CN2CCS(=O)(=O)CC2)c3OCOCc3c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B17 compound treatment 1051570.0 -4270.0 -0.02 999540.0 -49300.0 -0.29 913760.0 -150324.83870968 -0.860984374424832 -0.6783 -0.7456 2074823 Maybridge2_000391 CN(C)c1ccncc1C(O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B18 compound treatment 1059270.0 3430.0 0.02 1053690.0 4870.0 0.03 902270.0 -161814.83870968 -0.926793262344193 -0.5087 -0.5485 2074824 Maybridge2_000392 O=S1(=O)CCN(Cc2ccc(cc2)N3CCOCC3)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B19 compound treatment 997980.0 -57900.0 -0.28 1078480.0 29700.0 0.18 909990.0 -154094.83870968 -0.882577020852682 -0.5709 -0.6052 2074825 Maybridge2_000393 Fc1ccc(cc1)C2CCCN2S(=O)(=O)c3cccc4cccnc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B20 compound treatment 1111390.0 55500.0 0.27 1058020.0 9200.0 0.05 931750.0 -132334.83870968 -0.7579467857678 -0.2493 -0.309 2074826 Maybridge2_000394 FC(F)(F)c1ccc(cc1)S(=O)(=O)NCCN2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B21 compound treatment 1022040.0 -33800.0 -0.17 968160.0 -80700.0 -0.48 920590.0 -143494.83870968 -0.821865601188171 -0.8468 -0.8767 2074827 Maybridge2_000395 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B22 compound treatment 1099220.0 43400.0 0.21 1063390.0 14600.0 0.09 941080.0 -123004.83870968 -0.704509281478188 -0.2344 -0.3164 2074828 Maybridge2_000396 OC(CN1CCC(=CC1)c2ccccc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B23 mock treatment 1075570.0 19700.0 0.1 1087790.0 39000.0 0.23 946720.0 -117364.83870968 -0.672206224222732 -0.1987 -0.2769 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 B24 mock treatment 1017180.0 -38700.0 -0.19 963210.0 -85600.0 -0.51 952990.0 -111094.83870968 -0.636294846741932 -0.7703 -0.9209 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C01 compound treatment 1075200.0 19400.0 0.09 1017050.0 -31800.0 -0.19 1030580.0 -33504.8387096799 -0.191898709782558 -0.1653 -0.579 2074829 Maybridge2_000397 Fc1ccc(NC(=O)C2CN(Cc3ccco3)C(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C02 compound treatment 1031410.0 -24400.0 -0.12 979900.0 -68900.0 -0.41 989880.0 -74204.8387096799 -0.425007651324593 -0.5509 -0.9146 1122383 Maybridge2_000398 CN1CCN(CC1)c2cc(nc3ccccc23)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C03 compound treatment 1165630.0 110000.0 0.54 1107890.0 59100.0 0.35 995520.0 -68564.8387096799 -0.392704594069137 0.2858 0.3801 2074830 Maybridge2_000399 Cc1ccccc1Cn2cc(C)c(=O)[nH]c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C04 compound treatment 1040520.0 -15300.0 -0.07 1092980.0 44200.0 0.26 1048840.0 -15244.8387096799 -0.0873146981718066 0.058 0.2022 2074831 Maybridge2_000400 Clc1ccc(CS(=O)(=O)/C(=C/N2CCOCC2)/C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C05 compound treatment 1245630.0 190000.0 0.93 1289600.0 241000.0 1.43 1181340.0 117255.16129032 0.671578047634574 1.7498 0.9544 1009314 Maybridge2_000401 CCN(CC)c1ncnc2[nH]cnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C06 compound treatment 1189250.0 133000.0 0.65 1164430.0 116000.0 0.69 1111610.0 47525.1612903201 0.272200001105677 0.9304 0.9439 2074832 Maybridge2_000402 COc1ccc(cc1)C(=O)/C(=C/N2CCc3ccccc3C2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C07 compound treatment 1215610.0 160000.0 0.78 1230620.0 182000.0 1.08 889800.0 -174284.83870968 -0.998215092836311 0.4985 0.2993 2074833 Maybridge2_000403 Cc1cc(C)c2c(n1)sc3c(=O)n(CC=C)cnc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C08 compound treatment 1173190.0 117000.0 0.57 1220760.0 172000.0 1.02 963550.0 -100534.83870968 -0.575812526774269 0.5889 0.4509 1199989 Maybridge2_000404 C1C(CN1C(c2ccccc2)c3ccccc3)Sc4nc5ccccc5s4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C09 compound treatment 1177060.0 121000.0 0.59 1214330.0 166000.0 0.98 1011620.0 -52464.8387096799 -0.300491966088135 0.7367 0.6205 2074834 Maybridge2_000405 O=C(Nc1csc2ccccc12)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C10 compound treatment 824320.0 -232000.0 -1.13 882150.0 -167000.0 -0.99 717830.0 -346254.83870968 -1.98317196450668 -2.3703 -0.9523 2074835 Maybridge2_000406 CCN(CC)CC(=O)c1sc2ccc(Cl)cc2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C11 compound treatment 922620.0 -133000.0 -0.65 968520.0 -80300.0 -0.48 961320.0 -102764.83870968 -0.588584834873501 -0.9913 -0.9922 2074836 Maybridge2_000407 O=C(CN1CCc2ccccc12)N3CCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C12 compound treatment 938950.0 -117000.0 -0.57 974560.0 -74300.0 -0.44 804480.0 -259604.83870968 -1.48688474621141 -1.4431 -0.8731 2074837 Maybridge2_000408 Brc1ccc(cc1)n2nnnc2/C=C/N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C13 compound treatment 1204000.0 148000.0 0.72 1198980.0 150000.0 0.89 1203330.0 139245.16129032 0.797525605976327 1.3939 0.9963 2074838 Maybridge2_000409 O=C(CN1CCCc2ccccc12)N3CCCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C14 compound treatment 1085920.0 30100.0 0.15 1109040.0 60200.0 0.36 909950.0 -154134.83870968 -0.882806120549529 -0.2181 -0.2263 1480993 Maybridge2_000410 O=C(N1CCN(Cc2ccccc2)CC1)c3cc4CCc5ccccc5-c4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C15 compound treatment 1040450.0 -15400.0 -0.08 934580.0 -114000.0 -0.68 908480.0 -155604.83870968 -0.891225534408664 -0.9502 -0.846 2074839 Maybridge2_000411 Cc1sc(NC(=O)CN2CCc3ccccc23)c(C#N)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C16 compound treatment 1075160.0 19300.0 0.09 1031250.0 -17600.0 -0.1 916270.0 -147814.83870968 -0.84660836844767 -0.4946 -0.5763 2074840 Maybridge2_000412 Oc1cc(CN2CCCC2)nc(n1)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C17 compound treatment 1022260.0 -33600.0 -0.16 994120.0 -54700.0 -0.33 922720.0 -141364.83870968 -0.809666042331058 -0.75 -0.8447 2074841 Maybridge2_000413 CC(=O)Cn1cnc2sc(cc2c1=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C18 compound treatment 1056160.0 319.0 0.0 1235600.0 187000.0 1.11 1030830.0 -33254.8387096799 -0.190466836677263 0.5322 0.4723 2074842 Maybridge2_000414 Clc1ccc(cc1)C(=O)N(Cc2cccnc2)Cc3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C19 compound treatment 1093190.0 37300.0 0.18 1123200.0 74400.0 0.44 946560.0 -117524.83870968 -0.673122623010121 -0.0279 -0.0338 2074843 Maybridge2_000415 CC(=O)c1sc2nsc(SCCN3CCOCC3)c2c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C20 compound treatment 1056000.0 159.0 0.0 1020130.0 -28700.0 -0.17 1045140.0 -18944.8387096799 -0.108506420130174 -0.1607 -0.7948 2074844 Maybridge2_000416 COc1cc(c(cn1)C(=O)N(C)Cc2cccc(Cl)c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C21 compound treatment 1061760.0 5920.0 0.03 1005540.0 -43300.0 -0.26 962590.0 -101494.83870968 -0.581310919498602 -0.4675 -0.7346 2074845 Maybridge2_000417 Fc1ccc(cc1)N2CCN(CC2)C3=Cc4ccccc4CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C22 compound treatment 1107060.0 51200.0 0.25 1070400.0 21600.0 0.13 983740.0 -80344.8387096799 -0.46017445479064 -0.0471 -0.0874 2074846 Maybridge2_000418 COc1cccc(OC)c1CN(C)C(=O)c2cnccc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C23 mock treatment 1102200.0 46400.0 0.23 1060920.0 12100.0 0.07 990210.0 -73874.8387096799 -0.423117578825604 -0.072 -0.1483 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 C24 mock treatment 959970.0 -95900.0 -0.47 960830.0 -88000.0 -0.52 931950.0 -132134.83870968 -0.756801287283564 -1.0095 -0.9777 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D01 compound treatment 873390.0 -182000.0 -0.89 873780.0 -175000.0 -1.04 1010450.0 -53634.8387096799 -0.307193132220916 -1.293 -0.9206 1687697 Maybridge2_000419 Clc1ccccc1CN2CCN(CC2)c3cccc4[nH]ccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D02 compound treatment 927430.0 -128000.0 -0.63 889440.0 -159000.0 -0.95 861130.0 -202954.83870968 -1.16242230055155 -1.5805 -0.9722 2074847 Maybridge2_000420 Clc1ccc(NC(=O)OC2CN3CCC2CC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D03 compound treatment 1136880.0 81000.0 0.4 1256690.0 208000.0 1.24 1007970.0 -56114.8387096799 -0.321397313425443 0.7567 0.5659 1224648 Maybridge2_000421 O=C(N1CCN(Cc2ccccc2)CC1)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D04 compound treatment 1174690.0 119000.0 0.58 1139860.0 91000.0 0.54 1021560.0 -42524.8387096799 -0.243560691421603 0.5072 0.6108 2074848 Maybridge2_000422 Cc1noc(c1NC(=O)N2CCSCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D05 compound treatment 1160560.0 105000.0 0.51 1124680.0 75900.0 0.45 938940.0 -125144.83870968 -0.716766115259514 0.142 0.1435 2074849 Maybridge2_000423 Cc1nc(nc(O)c1Cc2c(F)cccc2Cl)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D06 compound treatment 1070160.0 14300.0 0.07 1074620.0 25800.0 0.15 1005360.0 -58724.8387096799 -0.336346068644723 -0.0652 -0.1734 2074850 Maybridge2_000424 Cc1ccc(cc1F)S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D07 compound treatment 1060110.0 4270.0 0.02 955760.0 -93100.0 -0.55 841600.0 -222484.83870968 -1.2742802275372 -1.0432 -0.7508 2074851 Maybridge2_000425 CN(C)C(=O)Oc1cc(C)nc(n1)c2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D08 compound treatment 1122110.0 66300.0 0.32 1216270.0 167000.0 1.0 973570.0 -90514.8387096799 -0.518423052714043 0.4625 0.3959 2074852 Maybridge2_000426 O=C(N1CCC(=CC1)c2ccccc2)c3csc(n3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D09 compound treatment 1094620.0 38800.0 0.19 956740.0 -92100.0 -0.55 827070.0 -237014.83870968 -1.35750069241695 -0.9905 -0.6711 2074853 Maybridge2_000427 CCc1cc(OC(=O)N(C)C)nc(n1)c2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D10 compound treatment 1104290.0 48400.0 0.24 1040920.0 -7900.0 -0.05 905920.0 -158164.83870968 -0.905887915006885 -0.4135 -0.441 2074854 Maybridge2_000428 O=S(=O)(N1CCC(=CC1)c2ccccc2)c3ccc4OCCCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D11 compound treatment 1079950.0 24100.0 0.12 1023230.0 -25600.0 -0.15 978950.0 -85134.8387096799 -0.487609143488093 -0.3014 -0.5749 2074855 Maybridge2_000429 CCN(CC)C(=O)Sc1c(Br)cc(Br)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D12 compound treatment 1316130.0 260000.0 1.27 1395910.0 347000.0 2.06 945690.0 -118394.83870968 -0.678105541416548 1.5344 0.6095 2074856 Maybridge2_000430 NC(=O)C1CCN(CC1)S(=O)(=O)Cc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D13 compound treatment 990240.0 -65600.0 -0.32 1098500.0 49700.0 0.3 946510.0 -117574.83870968 -0.67340899763118 -0.4033 -0.5027 2074637 Maybridge2_000431 CN1C/C(=C\c2cccs2)/C(=O)\C(=C\c3cccs3)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D14 compound treatment 1145320.0 89500.0 0.44 1116370.0 67500.0 0.4 935680.0 -128404.83870968 -0.735437740552562 0.0597 0.0632 2074857 Maybridge2_000432 CC1(C)Cc2cccc(C(=O)N3CCC(CC3)C(=O)c4ccc(Cl)cc4)c2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D15 compound treatment 1113240.0 57400.0 0.28 1035600.0 -13200.0 -0.08 1014840.0 -49244.8387096799 -0.282049440491935 -0.0463 -0.1142 2074858 Maybridge2_000433 CN1N=C/2C(CN(C)C\C2=C/c3ccc(cc3)C(F)(F)F)C1c4ccc(cc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D16 compound treatment 1075960.0 20100.0 0.1 1089230.0 40400.0 0.24 968360.0 -95724.8387096799 -0.548263288228392 -0.1211 -0.1996 2074859 Maybridge2_000434 O=S1(=O)CCN(Cc2ccc(cc2)n3cccn3)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D17 compound treatment 969860.0 -86000.0 -0.42 893140.0 -156000.0 -0.93 833640.0 -230444.83870968 -1.31987106720979 -1.5391 -0.9238 2074860 Maybridge2_000435 CC(=O)N1CCC(CC1)C(=O)Nc2nc3ccc(Cl)cc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D18 compound treatment 1042560.0 -13300.0 -0.06 989760.0 -59100.0 -0.35 937400.0 -126684.83870968 -0.725586453588132 -0.6592 -0.8151 2074861 Maybridge2_000436 O=S(=O)(N(Cc1ccccn1)Cc2ccccn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D19 compound treatment 1197290.0 141000.0 0.69 1009220.0 -39600.0 -0.24 983840.0 -80244.8387096799 -0.459601705548522 -0.0023 -0.0027 2074862 Maybridge2_000437 CN1CCOc2cc(ccc12)S(=O)(=O)N3CCCC3c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D20 compound treatment 1077800.0 22000.0 0.11 1036320.0 -12500.0 -0.07 1034650.0 -29434.8387096799 -0.168587815628354 -0.0783 -0.3673 2074863 Maybridge2_000438 Cc1cc(nn1C)C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D21 compound treatment 1091260.0 35400.0 0.17 1007040.0 -41800.0 -0.25 998420.0 -65664.8387096799 -0.376094866047714 -0.2607 -0.5399 2074864 Maybridge2_000439 Cc1ccc(cc1)S(=O)(=O)N2CCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D22 compound treatment 988080.0 -67800.0 -0.33 1092570.0 43700.0 0.26 1056980.0 -7104.8387096799 -0.0406929098633996 -0.0644 -0.1523 2074865 Maybridge2_000440 OC(CNCc1cc2ccccc2s1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D23 mock treatment 1043520.0 -12300.0 -0.06 1053490.0 4670.0 0.03 1029530.0 -34554.8387096799 -0.197912576824797 -0.133 -0.6372 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 D24 mock treatment 1008870.0 -47000.0 -0.23 1103200.0 54400.0 0.32 993010.0 -71074.8387096799 -0.407080600046299 -0.1808 -0.3182 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E01 compound treatment 1119140.0 63300.0 0.31 1163560.0 115000.0 0.68 1180160.0 116075.16129032 0.664819606577581 0.9563 0.9548 2074866 Maybridge2_000441 FC(F)(F)c1ccc(nc1)N2CCCN(CC2)C(=O)Nc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E02 compound treatment 530050.0 -526000.0 -2.57 540250.0 -509000.0 -3.02 467690.0 -596394.83870968 -3.4158469187407 -5.2014 -0.9934 2074867 Maybridge2_000442 CN(C)C(=O)Oc1ccnc(SCc2c(Cl)cccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E03 compound treatment 1179900.0 124000.0 0.61 1006080.0 -42700.0 -0.25 902300.0 -161784.83870968 -0.926621437571558 -0.3318 -0.292 1286698 Maybridge2_000443 CN(C)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E04 compound treatment 1227700.0 172000.0 0.84 1212480.0 164000.0 0.97 960540.0 -103544.83870968 -0.593052278962021 0.7043 0.4975 2074868 Maybridge2_000444 Cc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCSCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E05 compound treatment 1156540.0 101000.0 0.49 1168200.0 119000.0 0.71 1033860.0 -30224.8387096799 -0.173112534641087 0.594 0.6743 1538786 Maybridge2_000445 Clc1ccc(CNCc2cccnc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E06 compound treatment 1257760.0 202000.0 0.99 1140160.0 91300.0 0.54 1090130.0 26045.1612903201 0.149173463898725 0.9693 0.8532 2074869 Maybridge2_000446 CN(C)CC#Cc1ccc(s1)c2ccn(n2)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E07 compound treatment 998170.0 -57700.0 -0.28 1029950.0 -18900.0 -0.11 722400.0 -341684.83870968 -1.95699732414188 -1.3573 -0.6854 2074870 Maybridge2_000447 Cc1cc(C)c2c(n1)sc3c(ncnc32)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E08 compound treatment 1251960.0 196000.0 0.96 1235040.0 186000.0 1.11 1016610.0 -47474.8387096799 -0.271911778906446 1.0356 0.6953 2074871 Maybridge2_000448 OC(=O)CCCN1CCC(=CC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E09 compound treatment 1345210.0 289000.0 1.41 1301060.0 252000.0 1.5 1080250.0 16165.1612903201 0.0925858387774645 1.7357 0.8412 2074872 Maybridge2_000449 NC(=O)C1CCN(CC1)C(=O)Nc2csc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E10 compound treatment 1146400.0 90600.0 0.44 1136970.0 88100.0 0.52 1011240.0 -52844.8387096799 -0.302668413208183 0.3833 0.5113 2074873 Maybridge2_000450 CN(C)/C=C(\C#N)/C(=O)c1sc2ccc(Cl)cc2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E11 compound treatment 1049790.0 -6050.0 -0.03 1000610.0 -48200.0 -0.29 912990.0 -151094.83870968 -0.865394543589141 -0.6822 -0.748 2074874 Maybridge2_000451 O=C(CN1CCCc2ccccc12)N3CCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E12 compound treatment 986770.0 -69100.0 -0.34 1307680.0 259000.0 1.54 846400.0 -217684.83870968 -1.24678826391553 -0.0259 -0.0129 2074875 Maybridge2_000452 Brc1ccc(cc1)n2nnnc2/C=C/N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E13 compound treatment 1258150.0 202000.0 0.99 1143900.0 95100.0 0.57 1342490.0 278405.16129032 1.59456345130777 1.8177 0.9277 2074876 Maybridge2_000453 O=C(CN1CCc2ccccc12)N3CCCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E14 compound treatment 1116160.0 60300.0 0.29 1064020.0 15200.0 0.09 1010050.0 -54034.8387096799 -0.309484129189388 0.0436 0.0999 2074877 Maybridge2_000454 CN(CCC#N)c1ccc(/C=C\2/N=C(OC2=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E15 compound treatment 1211870.0 156000.0 0.76 1159650.0 111000.0 0.66 1045690.0 -18394.8387096799 -0.105356299298524 0.7598 0.7499 2074878 Maybridge2_000455 Cc1sc(NC(=O)CN2CCCC2)c(C#N)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E16 compound treatment 1054690.0 -1150.0 -0.01 1103870.0 55000.0 0.33 985570.0 -78514.8387096799 -0.44969314365988 -0.0739 -0.1328 2074879 Maybridge2_000456 CC1CN(CC(C)O1)c2nc(cc(c2C#N)C(F)(F)F)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E17 compound treatment 1094080.0 38200.0 0.19 1059840.0 11000.0 0.07 1001450.0 -62634.8387096799 -0.358740564011538 -0.0614 -0.1499 1247492 Maybridge2_000457 Clc1ccccc1Cn2cnc3sc(cc3c2=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E18 compound treatment 1069820.0 14000.0 0.07 1298370.0 250000.0 1.48 1082010.0 17925.1612903201 0.102666225438742 0.9555 0.6417 2074880 Maybridge2_000458 CC(C)(C)C(=O)N(Cc1ccc(Cl)cc1)Cc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E19 compound treatment 1277550.0 222000.0 1.08 1179550.0 131000.0 0.78 953830.0 -110254.83870968 -0.631483753108141 0.7096 0.481 2074881 Maybridge2_000459 Nc1c(sc2nsc(SCCN3CCCCC3)c12)C(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E20 compound treatment 1079140.0 23300.0 0.11 1088160.0 39300.0 0.23 965530.0 -98554.8387096799 -0.564472091780332 -0.1251 -0.2013 2074882 Maybridge2_000460 CCN(Cc1cccc(Cl)c1)C(=O)c2cnc(OC)cc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E21 compound treatment 1102820.0 47000.0 0.23 964340.0 -84500.0 -0.5 931360.0 -132724.83870968 -0.76018050781206 -0.5964 -0.6347 2074883 Maybridge2_000461 C(C1CCN(CC1)C2=Cc3ccccc3CC2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E22 compound treatment 1050310.0 -5530.0 -0.03 1063400.0 14600.0 0.09 1057520.0 -6564.8387096799 -0.0376000639559622 0.0127 0.1296 1203973 Maybridge2_000462 CN(C)c1ccncc1C(=O)Nc2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E23 mock treatment 1054810.0 -1030.0 -0.01 1023170.0 -25700.0 -0.15 1134790.0 70705.1612903201 0.404963275428634 0.1428 0.33 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 E24 mock treatment 1061010.0 5170.0 0.03 966040.0 -82800.0 -0.49 1183450.0 119365.16129032 0.683663056643264 0.1251 0.1484 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F01 compound treatment 923200.0 -133000.0 -0.65 860430.0 -188000.0 -1.12 1004200.0 -59884.8387096799 -0.342989959853292 -1.219 -0.9104 1379513 Maybridge2_000463 Clc1ccc(CN2CCN(CC2)c3cccc4[nH]ccc34)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F02 compound treatment 1080650.0 24800.0 0.12 1081760.0 32900.0 0.2 1116280.0 52195.1612903201 0.298947390712588 0.3557 0.9424 2074884 Maybridge2_000464 Cc1ccccc1NC(=O)OC2CN3CCC2CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F03 compound treatment 994850.0 -61000.0 -0.3 999700.0 -49100.0 -0.29 917510.0 -146574.83870968 -0.839506277845407 -0.8254 -0.8804 1240135 Maybridge2_000465 CN1CCN(CC1)c2c3C4CCC(C)(c3nc5ccccc25)C4(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F04 compound treatment 1188160.0 132000.0 0.65 1312100.0 263000.0 1.57 983630.0 -80454.8387096799 -0.46080447895697 1.0111 0.576 2074885 Maybridge2_000466 FC(F)(F)c1cccc(CS(=O)(=O)N2CCOCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F05 compound treatment 685670.0 -370000.0 -1.81 656810.0 -392000.0 -2.33 690410.0 -373674.83870968 -2.14021980669544 -3.6257 -0.9947 2074886 Maybridge2_000467 CN(C)C(=O)Oc1cc(C)nc(SCc2c(Cl)cccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F06 compound treatment 1266400.0 211000.0 1.03 1275870.0 227000.0 1.35 930520.0 -133564.83870968 -0.764991601445852 0.9318 0.5005 2074887 Maybridge2_000468 Fc1cccc(c1)C(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F07 compound treatment 1062500.0 6660.0 0.03 1020110.0 -28700.0 -0.17 1240480.0 176395.16129032 1.01030194942317 0.5035 0.4912 2074888 Maybridge2_000469 CCN(CC)C(=O)Oc1cc(C)nc(n1)c2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F08 compound treatment 1139770.0 83900.0 0.41 1173530.0 125000.0 0.74 1044820.0 -19264.8387096799 -0.110339217704951 0.6012 0.7035 2074889 Maybridge2_000470 Cc1c(Cl)cc(F)cc1S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F09 compound treatment 1141340.0 85500.0 0.42 1136520.0 87700.0 0.52 983920.0 -80164.8387096799 -0.459143506154827 0.2772 0.3419 2074890 Maybridge2_000471 CCCc1cc(=O)oc2cc(OC(=O)N(C)C)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F10 compound treatment 1240170.0 184000.0 0.9 1012720.0 -36100.0 -0.21 907290.0 -156794.83870968 -0.898041250389868 -0.1225 -0.095 1620449 Maybridge2_000472 Fc1ccccc1S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F11 compound treatment 893600.0 -162000.0 -0.79 907160.0 -142000.0 -0.84 814180.0 -249904.83870968 -1.43132806972596 -1.7704 -0.962 2074891 Maybridge2_000473 CCCN(CCC)S(=O)(=O)c1ccc(cc1)c2nc3ccc(C)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F12 compound treatment 1089130.0 33300.0 0.16 1138490.0 89700.0 0.53 1003140.0 -60944.8387096799 -0.349061101819743 0.2002 0.3044 2074892 Maybridge2_000474 O=S(=O)(N1CCCCC1c2cccnc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F13 compound treatment 1379810.0 324000.0 1.58 1063080.0 14300.0 0.08 1455530.0 391445.16129032 2.24199919459798 2.2572 0.8221 2074893 Maybridge2_000475 O=S(=O)(N1CCOCC1)c2csc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F14 compound treatment 1157240.0 101000.0 0.5 1105720.0 56900.0 0.34 1126570.0 62485.1612903201 0.357883287726533 0.688 0.9849 2074894 Maybridge2_000476 CN1CCN(CC1)C(=O)c2cccc3CC(C)(C)Oc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F15 compound treatment 1087140.0 31300.0 0.15 1130360.0 81500.0 0.48 994270.0 -69814.8387096799 -0.399863959595612 0.1374 0.2124 2074895 Maybridge2_000477 Cc1csc2c(=O)n(CCN3CCSCC3)c(=O)[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F16 compound treatment 1232800.0 177000.0 0.86 1115300.0 66500.0 0.4 1080890.0 16805.1612903201 0.0962514339270198 0.783 0.8194 2074896 Maybridge2_000478 Cn1cccc1CN2CCS(=O)(=O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F17 compound treatment 1183810.0 128000.0 0.63 1038080.0 -10700.0 -0.06 1054740.0 -9344.8387096799 -0.0535224928868433 0.2932 0.4648 2074897 Maybridge2_000479 CC(=O)N1CCC(CC1)C(=O)Nc2ccc3nc(C)ccc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F18 compound treatment 1061360.0 5520.0 0.03 1077450.0 28600.0 0.17 1036060.0 -28024.8387096799 -0.16051205131449 0.0212 0.0899 1398018 Maybridge2_000480 Clc1ccc(cc1)S(=O)(=O)N(Cc2ccccn2)Cc3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F19 compound treatment 1180000.0 124000.0 0.61 1106050.0 57200.0 0.34 956400.0 -107684.83870968 -0.616764097585707 0.1906 0.2051 2074898 Maybridge2_000481 Fc1ccc(cc1)C2CCCN2S(=O)(=O)c3ccc(cc3)c4cnco4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F20 compound treatment 1110360.0 54500.0 0.27 1083270.0 34400.0 0.2 1041190.0 -22894.8387096799 -0.131130015193835 0.1964 0.5443 2074899 Maybridge2_000482 Cc1cc(nn1C)C(=O)N2CCN=C(C=C2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F21 compound treatment 1018730.0 -37100.0 -0.18 1037470.0 -11400.0 -0.07 1015610.0 -48474.8387096799 -0.277639271327626 -0.304 -0.8982 2074900 Maybridge2_000483 Fc1ccccc1NC(=O)N2CCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F22 compound treatment 1076100.0 20300.0 0.1 1108440.0 59600.0 0.35 1147730.0 83645.1612903201 0.479077027358707 0.5384 0.8912 2074901 Maybridge2_000484 OC(CNCc1ccc(cc1)c2cccs2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F23 mock treatment 1169080.0 113000.0 0.55 1144560.0 95700.0 0.57 1048980.0 -15104.8387096799 -0.0865128492328414 0.5982 0.7491 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 F24 mock treatment 1118280.0 62400.0 0.31 1152090.0 103000.0 0.61 930130.0 -133954.83870968 -0.767225323490112 0.0877 0.0852 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G01 compound treatment 1269790.0 214000.0 1.05 1195920.0 147000.0 0.87 1051750.0 -12334.8387096799 -0.0706476952261722 1.0678 0.7823 2074902 Maybridge2_000485 CC(C)(C)NC(=O)N1CCCN(CC1)c2ccc(cn2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G02 compound treatment 968440.0 -87400.0 -0.43 940000.0 -109000.0 -0.65 812120.0 -251964.83870968 -1.44312670411359 -1.4533 -0.8872 2074903 Maybridge2_000486 CN(C)C(=O)Oc1ccnc(SCc2ccc(Cl)cc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G03 compound treatment 1157520.0 102000.0 0.5 1142690.0 93900.0 0.56 1018090.0 -45994.8387096799 -0.263435090123099 0.457 0.5768 2074904 Maybridge2_000487 COC(=O)C1Cc2c([nH]c3ccccc23)C(N1)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G04 compound treatment 1167850.0 112000.0 0.55 1066400.0 17600.0 0.1 978510.0 -85574.8387096799 -0.490129240153412 0.0933 0.1258 2074905 Maybridge2_000488 O=C1CS(=O)(=O)C(N1CC2CC2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G05 compound treatment 1195120.0 139000.0 0.68 1289600.0 241000.0 1.43 1042580.0 -21504.8387096799 -0.123168800728395 1.1484 0.7222 1288613 Maybridge2_000489 C(NCc1cccnc1)c2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G06 compound treatment 1275620.0 220000.0 1.07 1263220.0 214000.0 1.27 998400.0 -65684.8387096799 -0.376209415896138 1.1388 0.6665 2074906 Maybridge2_000490 ON=C1CC2CCCC(C1)N2Cc3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G07 compound treatment 962840.0 -93000.0 -0.45 868640.0 -180000.0 -1.07 817780.0 -246304.83870968 -1.41070909700971 -1.6954 -0.9271 2074907 Maybridge2_000491 CN1CCN(CC1)c2ncnc3c2sc4nc(C)cc(C)c43 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G08 compound treatment 1269920.0 214000.0 1.05 1211810.0 163000.0 0.97 983100.0 -80984.8387096799 -0.463840049940195 0.8957 0.5973 1401140 Maybridge2_000492 Brc1ccc(s1)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G09 compound treatment 1264500.0 209000.0 1.02 1173820.0 125000.0 0.74 1087220.0 23135.1612903201 0.132506460953091 1.0942 0.8625 2074908 Maybridge2_000493 CC1CCN(CC1)C(=O)Nc2csc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G10 compound treatment 1271900.0 216000.0 1.06 1360850.0 312000.0 1.86 1007810.0 -56274.8387096799 -0.322313712212832 1.4947 0.6923 2074909 Maybridge2_000494 Ic1ccc(NC(=O)CN2CCCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G11 compound treatment 1428920.0 373000.0 1.82 1258800.0 210000.0 1.25 1030840.0 -33244.8387096799 -0.190409561753051 1.6634 0.7501 2074910 Maybridge2_000495 O=C(CN1CCCC1)N2CCc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G12 compound treatment 1141070.0 85200.0 0.42 1361090.0 312000.0 1.86 1000800.0 -63284.8387096799 -0.362463434085305 1.1032 0.5695 1615107 Maybridge2_000496 CN(C)CCC(O)c1ccc2OCCCCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G13 compound treatment 1110080.0 54200.0 0.27 1147560.0 98700.0 0.59 1327590.0 263505.16129032 1.50922381423218 1.3633 0.8308 2074911 Maybridge2_000497 O=C(CN1CCN(CC1)c2ccccc2)N3CCCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G14 compound treatment 610450.0 -445000.0 -2.18 484850.0 -564000.0 -3.35 473380.0 -590704.83870968 -3.38325748686418 -5.146 -0.9826 1590454 Maybridge2_000498 CN(C)CCC(=O)Nc1nc(cs1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G15 compound treatment 904340.0 -152000.0 -0.74 771010.0 -278000.0 -1.65 778240.0 -285844.83870968 -1.63717414734318 -2.3264 -0.9531 1327521 Maybridge2_000499 CCN(CC)c1ncnc2sc(cc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G16 compound treatment 1007420.0 -48400.0 -0.24 900410.0 -148000.0 -0.88 881480.0 -182604.83870968 -1.04586782978053 -1.25 -0.9 2074912 Maybridge2_000500 CN(C)C(=O)Oc1cc(CSC(C)(C)C)nc(n1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G17 compound treatment 1087560.0 31700.0 0.15 1085030.0 36200.0 0.22 1029920.0 -34164.8387096799 -0.195678854780537 0.1008 0.3058 1511025 Maybridge2_000501 CCOC(=O)Cn1cnc2sc(cc2c1=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G18 compound treatment 1092880.0 37000.0 0.18 1090410.0 41600.0 0.25 1319680.0 255595.16129032 1.46391934918065 1.0925 0.7304 2074913 Maybridge2_000502 Clc1ccc(CN(Cc2cccnc2)S(=O)(=O)c3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G19 compound treatment 937280.0 -119000.0 -0.58 913460.0 -135000.0 -0.8 905670.0 -158414.83870968 -0.907319788112181 -1.323 -0.9843 2074914 Maybridge2_000503 Nc1c(sc2nsc(SCCN3CCOCC3)c12)C(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G20 compound treatment 1057070.0 1230.0 0.01 1118980.0 70200.0 0.42 1044680.0 -19404.8387096799 -0.111141066643916 0.1802 0.4173 2074915 Maybridge2_000504 CCN(Cc1cccc(Cl)c1Cl)C(=O)c2cnc(OC)cc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G21 compound treatment 274880.0 -781000.0 -3.82 263880.0 -785000.0 -4.67 184270.0 -879814.83870968 -5.0391328207516 -7.8072 -0.9936 2074916 Maybridge2_000505 CC1CCc2c(C#N)c(NC(=O)CN(Cc3ccccc3)Cc4ccccc4)sc2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G22 compound treatment 761310.0 -295000.0 -1.44 893660.0 -155000.0 -0.92 714020.0 -350064.83870968 -2.00499371063137 -2.5211 -0.9569 2074917 Maybridge2_000506 CN(C)/C=C/C(=O)c1cc(cc(c1O)C(C)(C)C)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G23 mock treatment 1030840.0 -25000.0 -0.12 1012520.0 -36300.0 -0.22 1045660.0 -18424.8387096799 -0.10552812407116 -0.2561 -0.95 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 G24 mock treatment 1124880.0 69000.0 0.34 1083120.0 34300.0 0.2 1200530.0 136445.16129032 0.781488627197023 0.7637 0.8725 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H01 compound treatment 943740.0 -112000.0 -0.55 1007460.0 -41400.0 -0.25 1021760.0 -42324.8387096799 -0.242415192937367 -0.5982 -0.9238 1462187 Maybridge2_000507 Fc1ccccc1CN2CCN(CC2)c3cccc4[nH]ccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H02 compound treatment 1162890.0 107000.0 0.52 1141350.0 92500.0 0.55 989870.0 -74214.8387096799 -0.425064926248805 0.3742 0.4301 2074918 Maybridge2_000508 Cc1cccc(NC(=O)OC2CN3CCC2CC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H03 compound treatment 1003710.0 -52100.0 -0.25 1044730.0 -4090.0 -0.02 1055970.0 -8114.8387096799 -0.0464776772087916 -0.1879 -0.7227 1623409 Maybridge2_000509 CN1CCN(CC1)c2cc(nc3ccccc23)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H04 compound treatment 1165030.0 109000.0 0.53 1164800.0 116000.0 0.69 947960.0 -116124.83870968 -0.665104133620469 0.3222 0.2938 2074919 Maybridge2_000510 FC(F)(F)c1cccc(CS(=O)(=O)N2CCCCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H05 compound treatment 980530.0 -75300.0 -0.37 952260.0 -96600.0 -0.57 893660.0 -170424.83870968 -0.976106972090555 -1.1075 -0.9301 2074920 Maybridge2_000511 CN(C)C(=O)Oc1cc(C)nc(n1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H06 compound treatment 1191720.0 136000.0 0.66 1039850.0 -8970.0 -0.05 948000.0 -116084.83870968 -0.664875033923621 -0.0314 -0.0333 2074921 Maybridge2_000512 O=C(N1CCC(=CC1)c2ccccc2)c3ccsc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H07 compound treatment 1194960.0 139000.0 0.68 1115040.0 66200.0 0.39 1086400.0 22315.1612903201 0.127809917167723 0.6936 0.8715 2074922 Maybridge2_000513 CC(C)CCc1c(C)nc(nc1O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H08 compound treatment 1107450.0 51600.0 0.25 1098400.0 49600.0 0.29 1027290.0 -36794.8387096799 -0.210742159848241 0.1941 0.4397 2074923 Maybridge2_000514 Clc1cc(Cl)cc(c1)S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H09 compound treatment 1030740.0 -25100.0 -0.12 1024180.0 -24600.0 -0.15 1167490.0 103405.16129032 0.592252277601228 0.1865 0.2997 2074924 Maybridge2_000515 CCCc1cc(OC(=O)N(C)C)nc(n1)c2cccc(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H10 compound treatment 1132600.0 76800.0 0.38 1149170.0 100000.0 0.6 1051540.0 -12544.8387096799 -0.07185046863462 0.5196 0.7334 2074925 Maybridge2_000516 COc1ccc(c(OC)c1)S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H11 compound treatment 1067890.0 12000.0 0.06 1100560.0 51700.0 0.31 945720.0 -118364.83870968 -0.677933716643912 -0.1798 -0.2407 2074926 Maybridge2_000517 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H12 compound treatment 1003580.0 -52300.0 -0.26 879440.0 -169000.0 -1.01 743220.0 -320864.83870968 -1.83775093193291 -1.79 -0.8479 2074927 Maybridge2_000518 Fc1ccc(CN2CCCN(Cc3ccc(F)cc3)C2c4ccco4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H13 compound treatment 1217620.0 162000.0 0.79 1320710.0 272000.0 1.62 1402840.0 338755.16129032 1.940217618926 2.51 0.9485 1939214 Maybridge2_000519 COc1ccc(cc1)N2C(=O)CC(N3CCSCC3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H14 compound treatment 1075140.0 19300.0 0.09 1072930.0 24100.0 0.14 928410.0 -135674.83870968 -0.777076610454542 -0.3114 -0.3914 2074928 Maybridge2_000520 CC1(C)Cc2cccc(C(=O)N3CCC(O)(CC3)c4ccc(Cl)cc4)c2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H15 compound treatment 1057550.0 1710.0 0.01 1075800.0 27000.0 0.16 1009460.0 -54624.8387096799 -0.312863349717884 -0.0832 -0.2365 2074929 Maybridge2_000521 O=C1CC2(CCCc3ccccc32)C(=O)N1CN4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H16 compound treatment 1148820.0 93000.0 0.45 1273200.0 224000.0 1.33 1017840.0 -46244.8387096799 -0.264866963228394 0.8797 0.6134 2074930 Maybridge2_000522 Cc1cc(CN2CCS(=O)(=O)CC2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H17 compound treatment 1035880.0 -20000.0 -0.1 1027100.0 -21700.0 -0.13 1048660.0 -15424.8387096799 -0.0883456468076191 -0.1819 -0.9864 2074931 Maybridge2_000523 CC(=O)N1CCC(CC1)C(=O)NCc2ccc(cc2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H18 compound treatment 1143230.0 87400.0 0.43 1092030.0 43200.0 0.26 1018240.0 -45844.8387096799 -0.262575966259922 0.2433 0.4319 2074932 Maybridge2_000524 OC1(CCN(CC1)C(=O)c2cnc3ccccc3n2)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H19 compound treatment 1111560.0 55700.0 0.27 1036290.0 -12500.0 -0.07 1263490.0 199405.16129032 1.14209155003453 0.7735 0.6575 2074933 Maybridge2_000525 Fc1ccc(cc1)C2CCCN2S(=O)(=O)c3ccc(Oc4ccccc4)nc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H20 compound treatment 1112420.0 56600.0 0.28 1093620.0 44800.0 0.27 1100440.0 36355.1612903201 0.208223910761093 0.4336 0.9929 2074934 Maybridge2_000526 Cc1cc(nn1C)C(=O)Nc2ccccc2N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H21 compound treatment 1038820.0 -17000.0 -0.08 1048480.0 -341.0 0.0 1048860.0 -15224.8387096799 -0.087200148323383 -0.0995 -0.8259 2074935 Maybridge2_000527 Cc1cccc(NC(=O)N2CCCC2c3cccnc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H22 compound treatment 1082080.0 26200.0 0.13 1073720.0 24900.0 0.15 1044290.0 -19794.8387096799 -0.113374788688177 0.094 0.4156 2074936 Maybridge2_000528 O=C(NCc1ccsc1)C2CCCCN2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H23 mock treatment 1089650.0 33800.0 0.17 1083070.0 34200.0 0.2 1269760.0 205675.16129032 1.17800292751533 0.8931 0.74 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 H24 mock treatment 1150730.0 94900.0 0.46 1098000.0 49200.0 0.29 1151540.0 87455.1612903201 0.500898773483403 0.7257 0.9773 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I01 compound treatment 1048120.0 -7720.0 -0.04 1094880.0 46100.0 0.27 1180480.0 116395.16129032 0.666652404152359 0.5212 0.7222 2074937 Maybridge2_000529 Cc1ccc(F)cc1NC(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I02 compound treatment 1329410.0 274000.0 1.34 1135640.0 86800.0 0.52 1003780.0 -60304.8387096799 -0.345395506670188 0.8703 0.5905 2074938 Maybridge2_000530 COc1cc(/N=C(/SCc2c(C)c(C)c(C)c(C)c2C)\N3CCOCC3)c(OC)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I03 compound treatment 1143840.0 88000.0 0.43 1121890.0 73100.0 0.43 1003790.0 -60294.8387096799 -0.345338231745976 0.2997 0.4269 2074939 Maybridge2_000531 Clc1cccnc1N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I04 compound treatment 1217660.0 162000.0 0.79 1153710.0 105000.0 0.62 970630.0 -93454.8387096799 -0.535261880432313 0.5075 0.445 2074940 Maybridge2_000532 CN(C)C(=O)CS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I05 compound treatment 1210340.0 154000.0 0.75 1097440.0 48600.0 0.29 1085630.0 21545.1612903201 0.123399748003414 0.674 0.8242 2074941 Maybridge2_000533 O=C(NC1CCCCC1)C2N(Cc3ccco3)C(=O)c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I06 compound treatment 1121220.0 65400.0 0.32 1160580.0 112000.0 0.66 1150490.0 86405.1612903201 0.494884906441164 0.8538 0.9615 1575317 Maybridge2_000534 O=C(Nc1ccccc1)OC2CN(C2)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I07 compound treatment 913760.0 -142000.0 -0.69 809600.0 -239000.0 -1.42 787520.0 -276564.83870968 -1.58402301767463 -2.1366 -0.9541 1985907 Maybridge2_000535 CCN(CC)c1ncnc2c1sc3nc(C)cc(C)c32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I08 compound treatment 1067170.0 11300.0 0.06 1140280.0 91500.0 0.54 1056540.0 -7544.8387096799 -0.0432130065287189 0.321 0.5854 1203540 Maybridge2_000536 O=S(=O)(N1CCN(Cc2ccccc2)CC1)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I09 compound treatment 1129710.0 73900.0 0.36 1092930.0 44100.0 0.26 1090810.0 26725.1612903201 0.153068158745128 0.4482 0.9502 2074942 Maybridge2_000537 CN1CCC(CNC(=O)Nc2csc3ccccc23)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I10 compound treatment 1097390.0 41500.0 0.2 1073980.0 25200.0 0.15 953950.0 -110134.83870968 -0.630796454017599 -0.1606 -0.2364 1098492 Maybridge2_000538 Ic1ccc(NC(=O)CN2CCCCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I11 compound treatment 1067680.0 11800.0 0.06 1033820.0 -15000.0 -0.09 1161390.0 97305.1612903201 0.557314573832029 0.3037 0.5352 2074943 Maybridge2_000539 O=C(CN1CCN(CC1)c2ccccc2)N3CCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I12 compound treatment 1408160.0 352000.0 1.72 1162560.0 114000.0 0.68 1050880.0 -13204.8387096799 -0.075630613632599 1.3407 0.7243 2074944 Maybridge2_000540 O=c1[nH]c2ccccc2c(=O)n1CCN3CCSCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I13 compound treatment 1103740.0 47900.0 0.23 1082330.0 33500.0 0.2 1408030.0 343945.16129032 1.96994330459192 1.3875 0.6959 2074945 Maybridge2_000541 CCN(CC)c1ncc(C#N)c(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I14 compound treatment 621650.0 -434000.0 -2.12 604170.0 -445000.0 -2.64 705690.0 -358394.83870968 -2.0527037224998 -3.9365 -0.9933 1477602 Maybridge2_000542 Clc1ccc(cc1)c2csc(NC(=O)CCN3CCCC3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I15 compound treatment 835650.0 -220000.0 -1.08 814510.0 -234000.0 -1.39 765150.0 -298934.83870968 -1.71214702313643 -2.4141 -0.9831 1285881 Maybridge2_000543 C1CCN(C1)c2ncnc3sc(cc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I16 compound treatment 1091080.0 35200.0 0.17 1069920.0 21100.0 0.13 1142600.0 78515.1612903201 0.449694991238052 0.4315 0.8671 2074946 Maybridge2_000544 CN1CSc2nc(C)cc(C)c2C1=N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I17 compound treatment 1054460.0 -1380.0 -0.01 1095550.0 46700.0 0.28 1002850.0 -61234.8387096799 -0.350722074621886 -0.046 -0.1027 2074947 Maybridge2_000545 CCOC(=O)c1cc(sc1NC(=O)CN2CCc3ccccc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I18 compound treatment 1085570.0 29700.0 0.15 1246400.0 198000.0 1.17 1059010.0 -5074.8387096799 -0.0290661002484037 0.7454 0.6295 2074948 Maybridge2_000546 CN(C)C(=O)Nc1cnccc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I19 compound treatment 816810.0 -239000.0 -1.17 835520.0 -213000.0 -1.27 817330.0 -246754.83870968 -1.41328646859924 -2.2225 -0.9969 2074949 Maybridge2_000547 Nc1c(sc2nsc(SCCN3CCOCC3)c12)C(=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I20 compound treatment 1121970.0 66100.0 0.32 1060840.0 12000.0 0.07 1221080.0 156995.16129032 0.899188596452277 0.7469 0.7796 2074950 Maybridge2_000548 COc1cc(c(cn1)C(=O)N(C)Cc2ccc(Cl)c(Cl)c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I21 compound treatment 1091100.0 35300.0 0.17 1007840.0 -41000.0 -0.24 961220.0 -102864.83870968 -0.589157584115619 -0.3814 -0.5775 1531885 Maybridge2_000549 C1C(CN1C(c2ccccc2)c3ccccc3)Oc4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I22 compound treatment 1065220.0 9380.0 0.05 1076510.0 27700.0 0.16 1224980.0 160895.16129032 0.921525816894879 0.6536 0.6973 2074951 Maybridge2_000550 COc1ccc2nccc([C@@H](O)C3CC4CCN3CC4C=C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I23 mock treatment 954410.0 -101000.0 -0.5 1044830.0 -3990.0 -0.02 1251760.0 187675.16129032 1.07490806393409 0.3208 0.271 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 I24 mock treatment 1042010.0 -13800.0 -0.07 1055540.0 6720.0 0.04 1031560.0 -32524.8387096799 -0.186285767209801 -0.1235 -0.6109 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J01 compound treatment 944550.0 -111000.0 -0.54 906430.0 -142000.0 -0.85 947810.0 -116274.83870968 -0.665963257483645 -1.1873 -0.9839 1277060 Maybridge2_000551 Clc1ccc(CN2CCN(CC2)c3cccc4[nH]ccc34)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J02 compound treatment 970680.0 -85200.0 -0.42 1024320.0 -24500.0 -0.15 793050.0 -271034.83870968 -1.5523499845855 -1.2206 -0.7564 2074952 Maybridge2_000552 FC(F)(F)c1cccc(NC(=O)OC2CN3CCC2CC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J03 compound treatment 782770.0 -273000.0 -1.33 735360.0 -313000.0 -1.86 667050.0 -397034.83870968 -2.27401402965421 -3.1594 -0.9785 1317869 Maybridge2_000553 CN1CCN(CC1)c2c3CCc4ccccc4-c3nc5ccccc25 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J04 compound treatment 1229020.0 173000.0 0.85 1256690.0 208000.0 1.24 1032670.0 -31414.8387096799 -0.179928250622291 1.0983 0.728 2074953 Maybridge2_000554 CN1CCN(CC1)S(=O)(=O)Cc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J05 compound treatment 1268760.0 213000.0 1.04 1285450.0 237000.0 1.41 1065760.0 1675.1612903201 0.00959447359456288 1.4186 0.8106 2074954 Maybridge2_000555 CC1CN(CC(C)O1)c2nc(O)cc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J06 compound treatment 1201340.0 145000.0 0.71 1108640.0 59800.0 0.36 1122420.0 58335.1612903201 0.334114194178635 0.8087 0.9379 2074955 Maybridge2_000556 O=C(N1CCC(=CC1)c2ccccc2)c3ccc4OCCc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J07 compound treatment 1272090.0 216000.0 1.06 1274410.0 226000.0 1.34 1055770.0 -8314.8387096799 -0.0476231756930276 1.357 0.7944 2074956 Maybridge2_000557 CC(C)CCc1c(C)nc(nc1O)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J08 compound treatment 1171070.0 115000.0 0.56 1224580.0 176000.0 1.05 993440.0 -70644.8387096799 -0.404617778305192 0.6949 0.554 2074957 Maybridge2_000558 O=S(=O)(N1CCC(=CC1)c2ccccc2)c3ccc4OCCc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J09 compound treatment 1084200.0 28400.0 0.14 1040130.0 -8690.0 -0.05 887850.0 -176234.83870968 -1.00938370305761 -0.5326 -0.5221 2074958 Maybridge2_000559 Oc1ccccc1/C=N/c2ccc(cc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J10 compound treatment 1045800.0 -10000.0 -0.05 1102660.0 53800.0 0.32 1086630.0 22545.1612903201 0.129127240424594 0.2311 0.6627 2074959 Maybridge2_000560 Clc1ccc(CS(=O)(=O)N2CCCCCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J11 compound treatment 965120.0 -90700.0 -0.44 1020830.0 -28000.0 -0.17 1102170.0 38085.1612903201 0.218132472649735 -0.2261 -0.4337 2074960 Maybridge2_000561 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2cc(ccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J12 compound treatment 1096230.0 40400.0 0.2 897120.0 -152000.0 -0.9 829650.0 -234434.83870968 -1.3427237619703 -1.1821 -0.7254 2074961 Maybridge2_000562 Fc1ccc(CN2CCCN(Cc3ccc(F)cc3)C2c4cccnc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J13 compound treatment 1463120.0 407000.0 1.99 1305810.0 257000.0 1.53 1051680.0 -12404.8387096799 -0.0710486196956548 1.9902 0.7929 2074962 Maybridge2_000563 Cc1ccc(N2C(=O)CC(N3CCSCC3)C2=O)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J14 compound treatment 1218880.0 163000.0 0.8 1122890.0 74100.0 0.44 1298930.0 234845.16129032 1.34507388144116 1.4908 0.9179 2074963 Maybridge2_000564 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cc(F)cc4COCOc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J15 compound treatment 572910.0 -483000.0 -2.36 802210.0 -247000.0 -1.47 821800.0 -242284.83870968 -1.38768457747657 -3.0101 -0.9693 2074964 Maybridge2_000565 Oc1cc2OCOc2cc1C(N3CCCC3)c4ccc(cc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J16 compound treatment 1007880.0 -48000.0 -0.23 1022560.0 -26300.0 -0.16 979410.0 -84674.8387096799 -0.48497449697435 -0.5055 -0.9013 2074965 Maybridge2_000566 O=S1(=O)CCN(Cc2csc(n2)c3cccs3)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J17 compound treatment 1092800.0 37000.0 0.18 1098630.0 49800.0 0.3 1105920.0 41835.1612903201 0.239610569229161 0.4136 0.981 2074966 Maybridge2_000567 CC(=O)N1CCC(CC1)C(=O)NCc2cc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J18 compound treatment 1184260.0 128000.0 0.63 1113700.0 64900.0 0.39 1083360.0 19275.1612903201 0.110398340207335 0.6487 0.871 2074967 Maybridge2_000568 O=C(N(Cc1ccccn1)Cc2ccccn2)c3csc(n3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J19 compound treatment 1101070.0 45200.0 0.22 1066250.0 17400.0 0.1 1036980.0 -27104.8387096799 -0.155242758287004 0.0978 0.3381 2074968 Maybridge2_000569 Cc1c(cnn1c2ccccc2)S(=O)(=O)N3CCCC3c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J20 compound treatment 1097600.0 41800.0 0.2 1067280.0 18500.0 0.11 1135730.0 71645.1612903201 0.410347118304544 0.4181 0.8872 2074969 Maybridge2_000570 OC(CN1CCCN(CC1)c2nc(ns2)c3ccccc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J21 compound treatment 1087680.0 31800.0 0.16 1084070.0 35200.0 0.21 1056360.0 -7724.8387096799 -0.0442439551645313 0.1853 0.6999 2074970 Maybridge2_000571 FC(F)(F)c1ccccc1NC(=O)N2CCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J22 compound treatment 1160960.0 105000.0 0.51 1120700.0 71900.0 0.43 1021120.0 -42964.8387096799 -0.246080788086923 0.4012 0.5635 2074971 Maybridge2_000572 Clc1cccc(c1)N2CCN(CC2)C(=O)c3cnc4ccccc4n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J23 mock treatment 1118370.0 62500.0 0.31 1088650.0 39800.0 0.24 1176230.0 112145.16129032 0.642310561362343 0.684 0.9124 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 J24 mock treatment 1073150.0 17300.0 0.08 992130.0 -56700.0 -0.34 1061210.0 -2874.8387096799 -0.0164656169218072 -0.1553 -0.4464 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K01 compound treatment 1086970.0 31100.0 0.15 1001610.0 -47200.0 -0.28 1179010.0 114925.16129032 0.658232990293224 0.3058 0.4179 2074972 Maybridge2_000573 CN(C)c1ccc(cc1)C(=O)Nc2ccc(Oc3c(Cl)cccc3Cl)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K02 compound treatment 1192050.0 136000.0 0.67 1175800.0 127000.0 0.76 1384160.0 320075.16129032 1.83322806049835 1.8786 0.8983 2074973 Maybridge2_000574 CC(C)c1ccc(/N=C(/SCc2c(C)c(C)c(C)c(C)c2C)\N3CCOCC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K03 compound treatment 1262130.0 206000.0 1.01 1176090.0 127000.0 0.76 1053020.0 -11064.8387096799 -0.0633737798512733 0.9823 0.7783 2074974 Maybridge2_000575 Cc1nnsc1C(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K04 compound treatment 1090080.0 34200.0 0.17 1141870.0 93000.0 0.55 1136000.0 71915.1612903201 0.411893541258262 0.6538 0.9212 2074975 Maybridge2_000576 Clc1ccc(cc1)S(=O)(=O)/C(=C/NN2CCCCC2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K05 compound treatment 1203590.0 148000.0 0.72 1325010.0 276000.0 1.64 1066640.0 2555.1612903201 0.0146346669252015 1.3734 0.7655 2074976 Maybridge2_000577 Cn1cnc2n(ncc2c1=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K06 compound treatment 1515840.0 460000.0 2.25 1395460.0 347000.0 2.06 1053330.0 -10754.8387096799 -0.0615982572007074 2.4521 0.8039 1199768 Maybridge2_000578 Clc1ccc(NC(=O)OC2CN(C2)C(c3ccccc3)c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K07 compound treatment 1099420.0 43600.0 0.21 985120.0 -63700.0 -0.38 717510.0 -346574.83870968 -1.98500476208145 -1.2418 -0.6111 2074977 Maybridge2_000579 Cc1cc(C)c2c(n1)sc3c(ncnc32)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K08 compound treatment 1171860.0 116000.0 0.57 1130080.0 81300.0 0.48 1083050.0 18965.1612903201 0.108622817556769 0.669 0.8887 1679524 Maybridge2_000580 Clc1ccc(s1)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K09 compound treatment 1185840.0 130000.0 0.64 1144110.0 95300.0 0.57 1371700.0 307615.16129032 1.76186350493044 1.7111 0.8745 2074978 Maybridge2_000581 O=C(Nc1csc2ccccc12)N3CCSCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K10 compound treatment 1236240.0 180000.0 0.88 1389630.0 341000.0 2.03 1165630.0 101545.16129032 0.581599141697833 2.0147 0.8816 1024901 Maybridge2_000582 Oc1ccc2ccccc2c1C(N3CCCCC3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K11 compound treatment 1247800.0 192000.0 0.94 1182680.0 134000.0 0.8 1074480.0 10395.1612903201 0.0595382075072545 1.0354 0.8407 2074979 Maybridge2_000583 CN1CCN(CC(=O)N2CCc3ccccc23)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K12 compound treatment 843520.0 -212000.0 -1.04 1006430.0 -42400.0 -0.25 879270.0 -184814.83870968 -1.05852558803134 -1.3556 -0.9017 1117813 Maybridge2_000584 Clc1ccc(cc1)c2nc3cc(CN4CCCCC4)ccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K13 compound treatment 1132920.0 77100.0 0.38 992160.0 -56700.0 -0.34 1258560.0 194475.16129032 1.11385501239811 0.666 0.5445 2074980 Maybridge2_000585 Nc1nc(ncc1C#N)N(Cc2ccccc2)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K14 compound treatment 1112110.0 56300.0 0.27 1273280.0 224000.0 1.33 1110410.0 46325.1612903201 0.26532701020026 1.0825 0.7797 2074981 Maybridge2_000586 Cc1cc(Br)ccc1NC(=O)CN2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K15 compound treatment 914720.0 -141000.0 -0.69 826830.0 -222000.0 -1.32 1006330.0 -57754.8387096799 -0.330790400996178 -1.3512 -0.8857 1696248 Maybridge2_000587 C1CN(CCO1)c2ncnc3sc(cc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K16 compound treatment 1058150.0 2310.0 0.01 1043400.0 -5420.0 -0.03 1003900.0 -60184.8387096799 -0.344708207579646 -0.2111 -0.6095 2074982 Maybridge2_000588 Cc1nc(C)nc(n1)N(Cc2ccccc2)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K17 compound treatment 1118820.0 63000.0 0.31 1099200.0 50400.0 0.3 1035930.0 -28154.8387096799 -0.161256625329243 0.2575 0.5614 2074983 Maybridge2_000589 CCOC(=O)c1cc(sc1NC(=O)CN2CCCCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K18 compound treatment 1212190.0 156000.0 0.76 1098910.0 50100.0 0.3 1085880.0 21795.1612903201 0.124831621108709 0.6851 0.826 2074984 Maybridge2_000590 CN(Cc1ccccc1Cl)C(=O)c2cnccc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K19 compound treatment 794650.0 -261000.0 -1.28 799110.0 -250000.0 -1.48 787040.0 -277044.83870968 -1.58677221403679 -2.5102 -0.996 2074985 Maybridge2_000591 Nc1c(sc2nsc(SCCN3CCCC3)c12)C(=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K20 compound treatment 1038520.0 -17300.0 -0.08 1042980.0 -5840.0 -0.03 1172250.0 108165.16129032 0.619515141526046 0.2888 0.4611 2074986 Maybridge2_000592 CN(Cc1c(C)cc(Cl)cc1Cl)C(=O)c2cnc(Oc3ccccc3)cc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K21 compound treatment 1066880.0 11000.0 0.05 923470.0 -125000.0 -0.75 968500.0 -95584.8387096799 -0.547461439289426 -0.7153 -0.7721 1684983 Maybridge2_000593 Fc1ccc2[nH]c3CCN(Cc4ccc(Cl)cc4Cl)Cc3c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K22 compound treatment 1062620.0 6780.0 0.03 1038310.0 -10500.0 -0.06 1312330.0 248245.16129032 1.42182227988497 0.8039 0.5647 1305796 Maybridge2_000594 Cc1cc(C)c(OC2CN(C2)C(c3ccccc3)c4ccccc4)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K23 mock treatment 1027930.0 -27900.0 -0.14 1077320.0 28500.0 0.17 1131450.0 67365.1612903201 0.385833450741892 0.2419 0.5461 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 K24 mock treatment 1130500.0 74700.0 0.36 1093160.0 44300.0 0.26 1010510.0 -53574.8387096799 -0.306849482675645 0.1857 0.3408 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L01 compound treatment 874010.0 -182000.0 -0.89 866430.0 -182000.0 -1.08 1081230.0 17145.1612903201 0.0981987813502211 -1.0824 -0.7702 1614244 Maybridge2_000595 C(N1CCN(CC1)c2cccc3[nH]ccc23)c4ccc5ccccc5c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L02 compound treatment 813650.0 -242000.0 -1.18 790210.0 -259000.0 -1.54 745550.0 -318534.83870968 -1.82440587459156 -2.6244 -0.9854 2074987 Maybridge2_000596 FC(F)(F)c1ccc(NC(=O)OC2CN3CCC2CC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L03 compound treatment 1017760.0 -38100.0 -0.19 1061340.0 12500.0 0.07 850150.0 -213934.83870968 -1.22531016733611 -0.7719 -0.6217 1550156 Maybridge2_000597 CC1C(N(C)C(CC1(O)c2ccc(F)cc2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L04 compound treatment 1069570.0 13700.0 0.07 1104190.0 55400.0 0.33 1161000.0 96915.1612903201 0.555080851787768 0.5493 0.8466 2074988 Maybridge2_000598 O=S(=O)(N1CCC(=CC1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L05 compound treatment 1260920.0 205000.0 1.0 1317650.0 269000.0 1.6 1005450.0 -58634.8387096799 -0.335830594326817 1.3076 0.6823 2074989 Maybridge2_000599 Oc1cc(nc(n1)N2CCCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L06 compound treatment 1098340.0 42500.0 0.21 1115470.0 66600.0 0.4 1084280.0 20195.1612903201 0.115667633234821 0.4155 0.899 2074990 Maybridge2_000600 O=C(N1CCC(=CC1)c2ccccc2)c3ccc(s3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L07 compound treatment 1240220.0 184000.0 0.9 1169510.0 121000.0 0.72 1084900.0 20815.1612903201 0.119218678535953 1.0033 0.8664 2074991 Maybridge2_000601 CC(=C)Cc1c(C)nc(nc1O)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L08 compound treatment 1412210.0 356000.0 1.74 1444050.0 395000.0 2.35 1063200.0 -884.838709679898 -0.00506790700365851 2.3592 0.8066 2074992 Maybridge2_000602 Cc1cc(c(o1)C(F)(F)F)S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L09 compound treatment 1158040.0 102000.0 0.5 1230300.0 181000.0 1.08 981850.0 -82234.8387096799 -0.47099941546667 0.6394 0.4999 2074993 Maybridge2_000603 C1CN=C(Nc2ccc(cc2)N3CCOCC3)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L10 compound treatment 1094350.0 38500.0 0.19 1076690.0 27900.0 0.17 957570.0 -106514.83870968 -0.610062931452926 -0.1479 -0.2243 2074994 Maybridge2_000604 CN1CCN(CC1)S(=O)(=O)Cc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L11 compound treatment 1436000.0 380000.0 1.86 1284920.0 236000.0 1.4 1068980.0 4895.1612903201 0.0280369991907632 1.8991 0.8156 1233213 Maybridge2_000605 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L12 compound treatment 947360.0 -108000.0 -0.53 912420.0 -136000.0 -0.81 1145290.0 81205.1612903201 0.465101945851027 -0.5058 -0.4706 2074995 Maybridge2_000606 Fc1ccc(CN2CCCN(Cc3ccc(F)cc3)C2c4cccs4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L13 compound treatment 1526140.0 470000.0 2.3 1356260.0 307000.0 1.83 1483550.0 419465.16129032 2.40248353223945 3.7692 0.9935 2074996 Maybridge2_000607 Cc1cccc(C)c1N2C(=O)CC(N3CCSCC3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L14 compound treatment 1123400.0 67600.0 0.33 1109280.0 60500.0 0.36 1198080.0 133995.16129032 0.767456270765131 0.8412 0.9249 2074997 Maybridge2_000608 O=C(N1CCSCC1)c2cccc3OCCCOc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L15 compound treatment 1101550.0 45700.0 0.22 1050560.0 1740.0 0.01 1046780.0 -17304.8387096799 -0.0991133325594379 0.0777 0.3177 2074998 Maybridge2_000609 CN(C)/C=C/1\C(=O)N(C(=O)\C1=N\c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L16 compound treatment 1066310.0 10500.0 0.05 1070300.0 21500.0 0.13 1034830.0 -29254.8387096799 -0.167556866992542 0.0065 0.0301 2074999 Maybridge2_000610 O=S1(=O)CCN(Cc2cc3ccccc3s2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L17 compound treatment 1098720.0 42900.0 0.21 1064210.0 15400.0 0.09 1135960.0 71875.1612903201 0.411664441561415 0.4115 0.8738 2075000 Maybridge2_000611 CC(=O)N1CCC(CC1)C(=O)Nc2cc(C)cc(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L18 compound treatment 1090170.0 34300.0 0.17 1075200.0 26400.0 0.16 1321140.0 257055.16129032 1.47228148811557 1.0374 0.6962 2075001 Maybridge2_000612 O=S(=O)(NCCN1CCCC1)c2cc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L19 compound treatment 1224770.0 169000.0 0.83 1247680.0 199000.0 1.18 1232330.0 168245.16129032 0.963622886190554 1.7156 0.9892 2075002 Maybridge2_000613 O=S(=O)(N1CCCC1c2cccnc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L20 compound treatment 1064880.0 9040.0 0.04 992580.0 -56200.0 -0.33 1275570.0 211485.16129032 1.21127965848239 0.5317 0.4229 2075003 Maybridge2_000614 OC(CN1CCC(O)(CC1)c2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L21 compound treatment 1103120.0 47300.0 0.23 1126470.0 77600.0 0.46 1062650.0 -1434.8387096799 -0.00821802783530764 0.3952 0.7654 2075004 Maybridge2_000615 Fc1ccccc1NC(=O)OC2CN3CCC2CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L22 compound treatment 1077120.0 21300.0 0.1 1155540.0 107000.0 0.63 1058360.0 -5724.8387096799 -0.0327889703221708 0.4075 0.6328 2075005 Maybridge2_000616 Clc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3cnc4ccccc4n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L23 mock treatment 1058010.0 2170.0 0.01 1118720.0 69900.0 0.42 1156510.0 92425.1612903201 0.529364410816669 0.5517 0.8196 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 L24 mock treatment 1174480.0 119000.0 0.58 1082720.0 33900.0 0.2 1021650.0 -42434.8387096799 -0.243045217103697 0.3107 0.4707 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M01 compound treatment 1073640.0 17800.0 0.09 1088190.0 39400.0 0.23 1058200.0 -5884.8387096799 -0.0337053691095597 0.1659 0.6584 2075006 Maybridge2_000617 O=C(OCC1CCCN2CCCCC12)/C=C/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M02 compound treatment 1347300.0 291000.0 1.42 1124910.0 76100.0 0.45 1167540.0 103455.16129032 0.592538652222287 1.4255 0.8868 1386650 Maybridge2_000618 Cc1c(CN2CCSCC2)c(=O)n(c3ccccc3)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M03 compound treatment 1134020.0 78200.0 0.38 1084910.0 36100.0 0.21 1103000.0 38915.1612903201 0.222886291359315 0.4731 0.9625 2075007 Maybridge2_000619 OC1(CCN(CC1)C(=O)c2cc(F)cc3COCOc23)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M04 compound treatment 50810.0 -1010000.0 -4.91 53120.0 -996000.0 -5.92 38610.0 -1025474.83870968 -5.87339936682071 -9.6445 -0.9965 2075008 Maybridge2_000620 CCOC(=O)c1sc(SC)c2C(=O)/C(=C/N(C)C)/CCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M05 compound treatment 1177840.0 122000.0 0.6 1063550.0 14700.0 0.09 1330020.0 265935.16129032 1.52314162081565 1.2741 0.7779 1333727 Maybridge2_000621 CCN(CC)c1ncnc2n(ncc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M06 compound treatment 1050970.0 -4870.0 -0.02 1111650.0 62800.0 0.37 1362880.0 298795.16129032 1.71134702177563 1.19 0.6793 1395190 Maybridge2_000622 Clc1cc(Cl)cc(NC(=O)OC2CN(C2)C(c3ccccc3)c4ccccc4)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M07 compound treatment 1122310.0 66500.0 0.32 1121770.0 72900.0 0.43 1031600.0 -32484.8387096799 -0.186056667512954 0.3305 0.5769 2075009 Maybridge2_000623 O=c1[nH]cc(N2CCCCCC2)c(=O)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M08 compound treatment 1095200.0 39400.0 0.19 1082310.0 33500.0 0.2 974430.0 -89654.8387096799 -0.513497409231828 -0.0705 -0.1208 2075010 Maybridge2_000624 CN1CCN(CC1)c2cc(nc3ccc(F)cc23)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M09 compound treatment 1299040.0 243000.0 1.19 1147100.0 98300.0 0.58 1384890.0 320805.16129032 1.83740912996581 2.0843 0.9203 2075011 Maybridge2_000625 Cc1cc(NC(=O)CN2CCCCC2)n(n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M10 compound treatment 745070.0 -311000.0 -1.52 525790.0 -523000.0 -3.11 763300.0 -300784.83870968 -1.72274288411561 -3.667 -0.9485 1150533 Maybridge2_000626 Oc1ccc2ccccc2c1C(N3CCCCC3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M11 compound treatment 1143100.0 87300.0 0.43 1099800.0 51000.0 0.3 1390670.0 326585.16129032 1.87051403616023 1.5011 0.7729 2075012 Maybridge2_000627 O=C(CN1CCOCC1)N2CCc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M12 compound treatment 1267470.0 212000.0 1.03 1206690.0 158000.0 0.94 1024120.0 -39964.8387096799 -0.228898310823382 1.0068 0.7114 2075013 Maybridge2_000628 FC(F)(F)c1ccc(cc1)C2C3N4CCC(CC4)C3=NN2c5cc(Cl)ccc5Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M13 compound treatment 1011870.0 -44000.0 -0.21 1086730.0 37900.0 0.23 1079270.0 15185.1612903201 0.0869728962047078 0.0563 0.1742 2075014 Maybridge2_000629 CCOC(=O)N1CCc2c(C#N)c(N)sc2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M14 compound treatment 977250.0 -78600.0 -0.38 1143200.0 94400.0 0.56 1192320.0 128235.16129032 0.734465914419133 0.5264 0.5259 2075015 Maybridge2_000630 Cc1cc(Br)ccc1NC(=O)CN2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M15 compound treatment 1000500.0 -55300.0 -0.27 1089640.0 40800.0 0.24 1008640.0 -55444.8387096799 -0.317559893503252 -0.1993 -0.413 1194772 Maybridge2_000631 Fc1ccc(Cn2cnc3sc(cc3c2=O)c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M16 compound treatment 879580.0 -176000.0 -0.86 842170.0 -207000.0 -1.23 974140.0 -89944.8387096799 -0.51515838203397 -1.5041 -0.948 2075016 Maybridge2_000632 Cc1nc(C)nc(n1)N(Cc2ccccc2Cl)Cc3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M17 compound treatment 967430.0 -88400.0 -0.43 978330.0 -70500.0 -0.42 1227520.0 163435.16129032 0.936073647644677 0.049 0.0441 2075017 Maybridge2_000633 CC(=O)c1sc2nsc(SCCN3CCCCC3)c2c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M18 compound treatment 1070170.0 14300.0 0.07 1082950.0 34100.0 0.2 1038750.0 -25334.8387096799 -0.145105096701515 0.0738 0.2849 2075018 Maybridge2_000634 COc1cc(c(cn1)C(=O)N(C)Cc2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M19 compound treatment 795330.0 -261000.0 -1.27 781920.0 -267000.0 -1.59 825800.0 -238284.83870968 -1.36477460779185 -2.4392 -0.9956 1488100 Maybridge2_000635 CN1CCN(CC1)c2ncnc3sc(cc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M20 compound treatment 966840.0 -89000.0 -0.43 1012820.0 -36000.0 -0.21 1186670.0 122585.16129032 0.702105582239465 0.0307 0.036 2075019 Maybridge2_000636 CN(Cc1c(C)cc(Cl)cc1Cl)C(=O)c2cnc(Oc3ccc(Cl)cc3)cc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M21 compound treatment 1019590.0 -36300.0 -0.18 1075380.0 26600.0 0.16 1210830.0 146745.16129032 0.840481799135179 0.4742 0.5429 1372843 Maybridge2_000637 CN(C)CCN1C(=O)c2ccccc2Sc3ccccc3S1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M22 compound treatment 974840.0 -81000.0 -0.4 965030.0 -83800.0 -0.5 959110.0 -104974.83870968 -0.601242593124309 -0.8633 -0.9861 2075020 Maybridge2_000638 CN(C)/C=C/C(=O)c1sc(nc1C)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M23 mock treatment 1090810.0 35000.0 0.17 989060.0 -59800.0 -0.36 1042500.0 -21584.8387096799 -0.123627000122089 -0.1779 -0.4305 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 M24 mock treatment 1106880.0 51000.0 0.25 1032480.0 -16300.0 -0.1 999840.0 -64244.8387096799 -0.367961826809638 -0.1246 -0.2738 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N01 compound treatment 1109040.0 53200.0 0.26 1109640.0 60800.0 0.36 1060510.0 -3574.8387096799 -0.0204748616166333 0.347 0.7784 1578630 Maybridge2_000639 Clc1cccc(Cl)c1C(=O)N2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N02 compound treatment 361630.0 -694000.0 -3.39 392760.0 -656000.0 -3.9 376660.0 -687424.83870968 -3.93722055384074 -6.4838 -0.9978 2075021 Maybridge2_000640 O=C(NCc1cc2ccccc2s1)c3ccccc3N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N03 compound treatment 1185520.0 130000.0 0.63 1127140.0 78300.0 0.47 1104530.0 40445.1612903201 0.231649354763721 0.7684 0.9374 1607897 Maybridge2_000641 CC1C(O)CC(N(C)C1c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N04 compound treatment 1238410.0 183000.0 0.89 1203470.0 155000.0 0.92 1332130.0 268045.16129032 1.53522662982434 1.9323 0.9664 2075022 Maybridge2_000642 O=S(=O)(N1CCC(=CC1)c2ccccc2)c3ccc4ccccc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N05 compound treatment 1314840.0 259000.0 1.27 1325040.0 276000.0 1.64 1238880.0 174795.16129032 1.00113796154928 2.2569 0.9802 2075023 Maybridge2_000643 Oc1cc(nc(n1)N2CCSCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N06 compound treatment 1137830.0 82000.0 0.4 1145870.0 97000.0 0.58 1134720.0 70635.1612903201 0.404562350959152 0.798 0.9844 2075024 Maybridge2_000644 O=C(N1CCC(=CC1)c2ccccc2)c3cc4ccccc4o3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N07 compound treatment 1150430.0 94600.0 0.46 1087140.0 38300.0 0.23 1059750.0 -4334.8387096799 -0.0248277558567303 0.384 0.7445 2075025 Maybridge2_000645 CN(C)C(=O)Oc1cc(C)nc(n1)c2ccc(C)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N08 compound treatment 1219200.0 163000.0 0.8 1148410.0 99600.0 0.59 1147630.0 83545.1612903201 0.478504278116589 1.079 0.9782 2075026 Maybridge2_000646 O=S(=O)(N1CCC(=CC1)c2ccccc2)c3ccc4OCCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N09 compound treatment 1198720.0 143000.0 0.7 1302190.0 253000.0 1.51 1084160.0 20075.1612903201 0.114980334144279 1.3393 0.8046 2075027 Maybridge2_000647 CC(C)(C)NC(=O)N1CCOCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N10 compound treatment 1070340.0 14500.0 0.07 1200220.0 151000.0 0.9 1112260.0 48175.1612903201 0.275922871179444 0.72 0.7625 2075028 Maybridge2_000648 Clc1ccc(CS(=O)(=O)N2CCc3ccccc3C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N11 compound treatment 1139040.0 83200.0 0.41 1019170.0 -29700.0 -0.18 1179200.0 115115.16129032 0.659321213853248 0.5135 0.6465 2075029 Maybridge2_000649 CN(C)c1ccc(/C=C\2/N=C(OC2=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N12 compound treatment 1001440.0 -54400.0 -0.27 992210.0 -56600.0 -0.34 1027410.0 -36674.8387096799 -0.210054860757699 -0.4691 -0.9822 2075030 Maybridge2_000650 Fc1ccc(CN2CCCN(Cc3ccc(F)cc3)C2c4csnn4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N13 compound treatment 1016320.0 -39500.0 -0.19 979970.0 -68900.0 -0.41 943360.0 -120724.83870968 -0.691450598757898 -0.7471 -0.904 2075031 Maybridge2_000651 Cc1ccc(cc1)N2C(=O)C(C(C2=O)c3ccccc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N14 compound treatment 1044990.0 -10900.0 -0.05 1141120.0 92300.0 0.55 1286440.0 222355.16129032 1.27353750110062 1.0216 0.7361 2075032 Maybridge2_000652 Cc1onc(c1CN2CCS(=O)(=O)CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N15 compound treatment 1095210.0 39400.0 0.19 1201210.0 152000.0 0.91 1133680.0 69595.1612903201 0.398605758841124 0.8644 0.8571 1611256 Maybridge2_000653 O=C(N1CCOCC1)c2ccc3ncsc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N16 compound treatment 1109020.0 53200.0 0.26 1066900.0 18100.0 0.11 1272880.0 208795.16129032 1.19587270386941 0.9025 0.7347 2075033 Maybridge2_000654 O=S1(=O)CCN(Cc2ccc3OCCCOc3c2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N17 compound treatment 1114660.0 58800.0 0.29 1157800.0 109000.0 0.65 1250990.0 186905.16129032 1.07049789476978 1.1581 0.902 2075034 Maybridge2_000655 CCOc1ccc(NC(=O)C2CCN(CC2)C(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N18 compound treatment 1022850.0 -33000.0 -0.16 997340.0 -51500.0 -0.31 1042480.0 -21604.8387096799 -0.123741549970513 -0.3413 -0.9287 2075035 Maybridge2_000656 CC1(C)CCc2cc(ccc2O1)S(=O)(=O)NCCN3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N19 compound treatment 1023380.0 -32500.0 -0.16 1056980.0 8160.0 0.05 1168010.0 103925.16129032 0.595230573660242 0.2801 0.4533 2075036 Maybridge2_000657 Fc1ccc(cc1)S(=O)(=O)N2CCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N20 compound treatment 1098130.0 42300.0 0.21 1142320.0 93500.0 0.56 1085130.0 21045.1612903201 0.120536001792824 0.5099 0.8424 2075037 Maybridge2_000658 OC(CN1CCC(CC1)c2c[nH]c3ccccc23)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N21 compound treatment 1047110.0 -8730.0 -0.04 1131450.0 82600.0 0.49 1164170.0 100085.16129032 0.57323700276291 0.59 0.7802 2075038 Maybridge2_000659 Fc1ccc(NC(=O)OC2CN3CCC2CC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N22 compound treatment 683300.0 -373000.0 -1.82 782720.0 -266000.0 -1.58 855360.0 -208724.83870968 -1.19546993182176 -2.6547 -0.9862 1730920 Maybridge2_000660 COc1ccc(CN2CCCN(Cc3ccc(OC)cc3)C2c4ccc(F)cc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N23 mock treatment 1083000.0 27200.0 0.13 1103200.0 54400.0 0.32 1187630.0 123545.16129032 0.707603974963798 0.6718 0.8513 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 N24 mock treatment 1015060.0 -40800.0 -0.2 1092860.0 44000.0 0.26 1075390.0 11305.1612903201 0.0647502256105285 0.0735 0.2193 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O01 compound treatment 990480.0 -65400.0 -0.32 1044970.0 -3850.0 -0.02 1012330.0 -51754.8387096799 -0.296425446469097 -0.3687 -0.8451 2075039 Maybridge2_000661 O=C(OCC1CCCN2CCCCC12)c3cc4ccccc4oc3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O02 compound treatment 1091150.0 35300.0 0.17 1228040.0 179000.0 1.07 1086610.0 22525.1612903201 0.129012690576171 0.7894 0.726 2075040 Maybridge2_000662 CCN/C=C(\C#N)/S(=O)(=O)c1ccc(Br)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O03 compound treatment 1235790.0 180000.0 0.88 1263890.0 215000.0 1.28 1239640.0 175555.16129032 1.00549085578938 1.8265 0.9877 2075041 Maybridge2_000663 Cc1onc(c1C(=O)N2CCNCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O04 compound treatment 1043170.0 -12700.0 -0.06 1027700.0 -21100.0 -0.13 1017980.0 -46104.8387096799 -0.264065114289429 -0.2607 -0.8723 2075042 Maybridge2_000664 CN(C)/C=C/C(=O)c1ccc(s1)c2cc(n(C)n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O05 compound treatment 1043890.0 -12000.0 -0.06 1066880.0 18100.0 0.11 1132400.0 68315.1612903201 0.391274568542014 0.2542 0.6201 2075043 Maybridge2_000665 CCN(CC)CC(=O)Nc1cc(C)nn1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O06 compound treatment 1169490.0 114000.0 0.56 1109700.0 60900.0 0.36 1384570.0 320485.16129032 1.83557633239103 1.5894 0.8144 1620788 Maybridge2_000666 Clc1ccc(SC2CN(C2)C(c3ccccc3)c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O07 compound treatment 1218940.0 163000.0 0.8 1202890.0 154000.0 0.92 1237320.0 173235.16129032 0.992203073372244 1.5619 0.996 1257903 Maybridge2_000667 Cc1ccc(cc1)S(=O)(=O)N2CCCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O08 compound treatment 951320.0 -105000.0 -0.51 923080.0 -126000.0 -0.75 1099150.0 35065.1612903201 0.200835445537771 -0.6106 -0.6583 2075044 Maybridge2_000668 CCN(CC)C(=O)c1ccc(s1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O09 compound treatment 1063890.0 8050.0 0.04 848100.0 -201000.0 -1.19 1150990.0 86905.1612903201 0.497748652651754 -0.379 -0.293 2075045 Maybridge2_000669 Fc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)CN5CCCCC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O10 compound treatment 1132230.0 76400.0 0.37 1089490.0 40700.0 0.24 1246720.0 182635.16129032 1.04604150213134 0.959 0.8437 2075046 Maybridge2_000670 COc1cc2CCN3CC(=O)Nc4ccccc4C3c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O11 compound treatment 953540.0 -102000.0 -0.5 1010620.0 -38200.0 -0.23 1136700.0 72615.1612903201 0.415902785953089 -0.1796 -0.2608 2075047 Maybridge2_000671 CN1CCN(CC1)c2nnc(c3ccccc3)c(n2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O12 compound treatment 1173520.0 118000.0 0.57 1204160.0 155000.0 0.92 1256480.0 192395.16129032 1.10194182816206 1.5015 0.9696 1311955 Maybridge2_000672 O=C1N(C2CCN(Cc3ccccc3)CC2)C(=O)c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O13 compound treatment 1086630.0 30800.0 0.15 1008090.0 -40700.0 -0.24 1178300.0 114215.16129032 0.654166470674186 0.3247 0.455 2075048 Maybridge2_000673 Cc1sc(NC(=O)CN2CCOCC2)c(C#N)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O14 compound treatment 1102260.0 46400.0 0.23 1092280.0 43500.0 0.26 1266200.0 202115.16129032 1.15761305449593 0.9485 0.7854 2075049 Maybridge2_000674 FC(F)(F)c1cc(NC(=O)CN2CCCC2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O15 compound treatment 784360.0 -271000.0 -1.33 945560.0 -103000.0 -0.61 932220.0 -131864.83870968 -0.755254864329845 -1.5564 -0.946 2075050 Maybridge2_000675 O=C(Cn1cnc2sc(cc2c1=O)c3ccccc3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O16 compound treatment 336700.0 -719000.0 -3.51 373300.0 -676000.0 -4.02 346610.0 -717474.83870968 -4.1093317010972 -6.7203 -0.9977 2075051 Maybridge2_000676 CN(C)C(=O)Oc1nc(cs1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O17 compound treatment 863700.0 -192000.0 -0.94 830820.0 -218000.0 -1.3 867630.0 -196454.83870968 -1.12519359981388 -1.9401 -0.9916 2075052 Maybridge2_000677 Nc1c(sc2nsc(SCCN3CCCCC3)c12)C(=O)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O18 compound treatment 1076640.0 20800.0 0.1 1067730.0 18900.0 0.11 1055360.0 -8724.8387096799 -0.0499714475857115 0.0947 0.5937 2075053 Maybridge2_000678 CCOc1cc(c(cn1)C(=O)N(C)Cc2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O19 compound treatment 1006980.0 -48900.0 -0.24 995380.0 -53400.0 -0.32 1048690.0 -15394.8387096799 -0.0881738220349837 -0.3722 -0.9142 1249246 Maybridge2_000679 C=CCn1cnc2sc(cc2c1=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O20 compound treatment 1076640.0 20800.0 0.1 1088690.0 39900.0 0.24 1018460.0 -45624.8387096799 -0.261315917927262 0.0447 0.1217 2075054 Maybridge2_000680 COc1cccc(OC)c1CN(C)C(=O)c2cnc(SC)cc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O21 compound treatment 997230.0 -58600.0 -0.29 1012610.0 -36200.0 -0.22 931290.0 -132794.83870968 -0.760581432281543 -0.7288 -0.8668 1166834 Maybridge2_000681 C=CCN1Cc2ccc3ccccc3c2-c4c(C1)ccc5ccccc45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O22 compound treatment 971090.0 -84800.0 -0.41 858610.0 -190000.0 -1.13 983140.0 -80944.8387096799 -0.463610950243348 -1.1598 -0.8986 1560070 Maybridge2_000682 C(N1CCN(CC1)c2cccc3[nH]ccc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O23 mock treatment 1057630.0 1790.0 0.01 1137960.0 89100.0 0.53 1253540.0 189455.16129032 1.08510300044379 0.9376 0.7763 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 O24 mock treatment 1080870.0 25000.0 0.12 955750.0 -93100.0 -0.55 950740.0 -113344.83870968 -0.649181704689587 -0.6237 -0.7238 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P01 compound treatment 916250.0 -140000.0 -0.68 802740.0 -246000.0 -1.46 885500.0 -178584.83870968 -1.02284331024739 -1.8292 -0.9571 1561821 Maybridge2_000683 Cc1cc(c(C)cc1Cl)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P02 compound treatment 1018630.0 -37200.0 -0.18 1031120.0 -17700.0 -0.11 1044930.0 -19154.8387096799 -0.109709193538621 -0.2291 -0.9666 2075055 Maybridge2_000684 O=C(NCc1cccs1)c2ccccc2N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P03 compound treatment 1193150.0 137000.0 0.67 1068770.0 19900.0 0.12 993350.0 -70734.8387096799 -0.405133252623098 0.2219 0.28 2075056 Maybridge2_000685 Fc1cccc(NC(=O)CN2CCCCC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P04 compound treatment 1085680.0 29800.0 0.15 1071060.0 22200.0 0.13 1028670.0 -35414.8387096799 -0.202838220307012 0.0434 0.1536 2075057 Maybridge2_000686 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCC(=CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P05 compound treatment 1253790.0 198000.0 0.97 1281610.0 233000.0 1.38 1184890.0 120805.16129032 0.691910645729764 1.7571 0.9628 2075058 Maybridge2_000687 CCN(CC)C(=O)Oc1cc(nc(n1)c2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P06 compound treatment 1093600.0 37800.0 0.18 1042240.0 -6580.0 -0.04 1164570.0 100485.16129032 0.575527999731382 0.4162 0.6872 2075059 Maybridge2_000688 O=C(N1CCC(=CC1)c2ccccc2)c3ccc4occc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P07 compound treatment 956030.0 -99800.0 -0.49 944550.0 -104000.0 -0.62 1036000.0 -28084.8387096799 -0.160855700859761 -0.7324 -0.9097 2075060 Maybridge2_000689 CN(C)C(=O)Oc1nc(nc(C)c1CC(=C)C)c2ccc(C)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P08 compound treatment 1067620.0 11800.0 0.06 1084080.0 35300.0 0.21 1024600.0 -39484.8387096799 -0.226149114461215 0.0237 0.0756 2075061 Maybridge2_000690 O=S(=O)(N1CCC(=CC1)c2ccccc2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P09 compound treatment 1121180.0 65300.0 0.32 1158820.0 110000.0 0.65 1059550.0 -4534.8387096799 -0.0259732543409664 0.547 0.751 2075062 Maybridge2_000691 CC(=O)N1C(CSC1c2ccc(C)cc2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P10 compound treatment 999950.0 -55900.0 -0.27 929280.0 -120000.0 -0.71 1132670.0 68585.1612903201 0.392820991495732 -0.3413 -0.3983 2075063 Maybridge2_000692 FC(F)(F)C1=NCCN(C=C1)S(=O)(=O)Cc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P11 compound treatment 25570.0 -1030000.0 -5.03 26590.0 -1020000.0 -6.08 26460.0 -1037624.83870968 -5.94298839973805 -9.847 -0.9967 2071191 Maybridge2_000693 CN1C/C(=C\c2ccccc2Cl)/C(=O)\C(=C\c3ccccc3Cl)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P12 compound treatment 1003970.0 -51900.0 -0.25 1056340.0 7520.0 0.04 1185570.0 121485.16129032 0.695805340576167 0.2812 0.3791 2075064 Maybridge2_000694 CC1(C)Cc2cccc(C(=O)NC3CCN(Cc4ccccc4)CC3)c2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P13 compound treatment 1084210.0 28400.0 0.14 1051150.0 2330.0 0.01 968560.0 -95524.8387096799 -0.547117789744156 -0.2279 -0.4036 2075065 Maybridge2_000695 Cc1ccc(cc1)N2C(=O)C(C(C2=O)c3ccccc3)N4CCSCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P14 compound treatment 1098340.0 42500.0 0.21 1187370.0 139000.0 0.82 1057830.0 -6254.8387096799 -0.0358245413053964 0.5749 0.676 2075066 Maybridge2_000696 Cc1cc(CN2CCS(=O)(=O)CC2)c(o1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P15 compound treatment 963570.0 -92300.0 -0.45 1095470.0 46600.0 0.28 1178600.0 114515.16129032 0.65588471840054 0.2786 0.3305 2075067 Maybridge2_000697 Fc1ccc(cc1)C(=O)N2CCN=C(C=C2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P16 compound treatment 1180590.0 125000.0 0.61 1066090.0 17300.0 0.1 1064660.0 575.161290320102 0.00329423193126463 0.4131 0.6683 2075068 Maybridge2_000698 CN1CCN(CC1)c2ccc(CN3CCS(=O)(=O)CC3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P17 compound treatment 1113990.0 58100.0 0.28 1003490.0 -45300.0 -0.27 1127400.0 63315.1612903201 0.362637106436112 0.2178 0.408 2075069 Maybridge2_000699 Fc1ccc(cc1)C2CCCN2S(=O)(=O)c3ccc(s3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P18 compound treatment 1150980.0 95100.0 0.46 1021000.0 -27800.0 -0.17 1130250.0 66165.1612903201 0.378960459836476 0.3916 0.6295 2075070 Maybridge2_000700 Clc1ccc(cc1)S(=O)(=O)NCCN2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P19 compound treatment 1102940.0 47100.0 0.23 1146140.0 97300.0 0.58 998300.0 -65784.8387096799 -0.376782165138256 0.2494 0.3427 2075071 Maybridge2_000701 Clc1ccc(cc1)S(=O)(=O)N2CCCC2c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P20 compound treatment 1072480.0 16600.0 0.08 963590.0 -85200.0 -0.51 981760.0 -82324.8387096799 -0.471514889784577 -0.5179 -0.7431 2075072 Maybridge2_000702 Cc1cc(N2CCN(CC(O)C(F)(F)F)CC2)c3ccccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P21 compound treatment 958450.0 -97400.0 -0.48 936420.0 -112000.0 -0.67 923140.0 -140944.83870968 -0.807260495514162 -1.1267 -0.9789 2075073 Maybridge2_000703 Clc1ccccc1NC(=O)OC2CN3CCC2CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P22 compound treatment 650350.0 -405000.0 -1.98 525490.0 -523000.0 -3.11 624170.0 -439914.83870968 -2.51960890467442 -4.3952 -0.9838 1672764 Maybridge2_000704 COc1ccc(CN2CCCN(Cc3ccc(OC)cc3)C2c4cccc(C)n4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P23 mock treatment 988160.0 -67700.0 -0.33 1117170.0 68300.0 0.41 1035370.0 -28714.8387096799 -0.164464021085104 -0.0512 -0.0933 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1304 P24 mock treatment 908160.0 -148000.0 -0.72 904060.0 -145000.0 -0.86 762690.0 -301394.83870968 -1.72623665449253 -1.9102 -0.9275 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A01 compound treatment 728530.0 -344000.0 -1.68 724590.0 -245000.0 -1.45 674920.0 -378320.9375 -2.16683030230505 -3.0621 -0.9862 2125345 Peakdale2_000001 Cc1ccc(cc1)c2cnc(NCCC#N)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A02 compound treatment 801950.0 -271000.0 -1.32 861150.0 -108000.0 -0.64 887440.0 -165800.9375 -0.949623612955827 -1.6834 -0.9612 2125346 Peakdale2_000002 Cn1cc(cn1)c2ccccc2NC(=O)Nc3ccc(F)cc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A03 compound treatment 841460.0 -231000.0 -1.13 896320.0 -72800.0 -0.43 873320.0 -179920.9375 -1.03049580594289 -1.4979 -0.942 2125347 Peakdale2_000003 COCCNc1ncc(cn1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A04 compound treatment 856200.0 -217000.0 -1.06 871520.0 -97600.0 -0.58 854040.0 -199200.9375 -1.14092185982325 -1.6052 -0.9662 2125348 Peakdale2_000004 Fc1ccc(cc1)c2cnc(NCCC#N)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A05 compound treatment 785450.0 -287000.0 -1.4 877990.0 -91100.0 -0.54 920160.0 -133080.9375 -0.76222006093481 -1.5639 -0.9268 2125349 Peakdale2_000005 COc1ccc(cc1)c2cnc(NCc3ccncc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A06 compound treatment 809780.0 -263000.0 -1.29 780830.0 -188000.0 -1.12 892520.0 -160720.9375 -0.920527951456232 -1.9202 -0.9911 2125350 Peakdale2_000006 Fc1ccc(cc1)c2cnc(nc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A07 compound treatment 843760.0 -229000.0 -1.12 809880.0 -159000.0 -0.95 829670.0 -223570.9375 -1.28050085012741 -1.9325 -0.9926 2125351 Peakdale2_000007 COc1ccc(cc1)c2cnc(nc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A08 compound treatment 906690.0 -166000.0 -0.81 915080.0 -54000.0 -0.32 953600.0 -99640.9375 -0.570692714370543 -0.984 -0.943 2125352 Peakdale2_000008 Fc1ccc(cc1)c2cnc(NCc3ccco3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A09 compound treatment 943270.0 -130000.0 -0.63 927360.0 -41800.0 -0.25 888930.0 -164310.9375 -0.941089649248269 -1.0525 -0.9063 2125353 Peakdale2_000009 Cc1ccc(cc1)c2cnc(NCC=C)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A10 compound treatment 1051200.0 -21700.0 -0.11 914240.0 -54900.0 -0.33 1007600.0 -45640.9375 -0.261408123626811 -0.4007 -0.9287 2125354 Peakdale2_000010 Clc1ccc(CNc2ncc(cn2)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A11 compound treatment 975570.0 -97400.0 -0.48 881790.0 -87300.0 -0.52 958880.0 -94360.9375 -0.540451554386712 -0.8865 -0.9986 2125355 Peakdale2_000011 OC1CCN(CC1)c2ncc(cn2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A12 compound treatment 807240.0 -266000.0 -1.3 770610.0 -199000.0 -1.18 854200.0 -199040.9375 -1.14000546103586 -2.0892 -0.9985 2125356 Peakdale2_000012 CCN(CC)c1cc(nc(C)n1)c2cncc(c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A13 compound treatment 733390.0 -340000.0 -1.66 694090.0 -275000.0 -1.64 819040.0 -234200.9375 -1.34138409456456 -2.6765 -0.9957 2125357 Peakdale2_000013 Cc1ccc(cc1)c2cnc(nc2)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A14 compound treatment 825320.0 -248000.0 -1.21 849940.0 -119000.0 -0.71 924860.0 -128380.9375 -0.735300846555263 -1.5322 -0.9678 2125358 Peakdale2_000014 Cc1nc(cc(n1)c2cncc(c2)c3ccccc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A15 compound treatment 997790.0 -75100.0 -0.37 1000690.0 31600.0 0.19 1032490.0 -20750.9375 -0.118850837263635 -0.1722 -0.4013 2125359 Peakdale2_000015 CC(Nc1ncc(cn1)c2ccc(Cl)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A16 compound treatment 870900.0 -202000.0 -0.99 884590.0 -84500.0 -0.5 1005210.0 -48030.9375 -0.275096830513431 -1.019 -0.8927 2125360 Peakdale2_000016 CN(Cc1ccccc1)c2cc(nc(C)n2)c3cncc(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A17 compound treatment 981680.0 -91300.0 -0.45 879390.0 -89700.0 -0.53 952930.0 -100310.9375 -0.574530134292734 -0.8972 -0.9947 2125361 Peakdale2_000017 C1CCC(CC1)Nc2ncc(cn2)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A18 compound treatment 581950.0 -491000.0 -2.4 644650.0 -324000.0 -1.93 766470.0 -286770.9375 -1.642478371146 -3.4473 -0.988 2125362 Peakdale2_000018 CN1CCN(CC1)c2cc(nc(C)n2)c3cncc(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A19 compound treatment 1046630.0 -26300.0 -0.13 984220.0 15100.0 0.09 990040.0 -63200.9375 -0.361982890542736 -0.2314 -0.5865 2125363 Peakdale2_000019 Cc1ccccc1C(=O)Nc2ccccc2c3cnn(C)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A20 compound treatment 828190.0 -245000.0 -1.2 866360.0 -103000.0 -0.61 1016480.0 -36760.9375 -0.21054799092673 -1.1648 -0.8569 2125364 Peakdale2_000020 Cc1nc(NCc2ccccc2)cc(n1)c3cncc(c3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A21 compound treatment 913960.0 -159000.0 -0.78 953300.0 -15800.0 -0.09 1013920.0 -39320.9375 -0.225210371524952 -0.6328 -0.7772 2125365 Peakdale2_000021 Cn1cc(cn1)c2ccccc2NC(=O)Cc3cc(F)cc(F)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A22 compound treatment 856590.0 -216000.0 -1.06 797440.0 -172000.0 -1.02 954690.0 -98550.9375 -0.564449747631457 -1.5256 -0.9691 2125366 Peakdale2_000022 CC(Nc1cc(nc(C)n1)c2cncc(c2)c3ccc(F)cc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A23 mock treatment 831000.0 -242000.0 -1.18 943740.0 -25400.0 -0.15 1030500.0 -22740.9375 -0.130248547181783 -0.8448 -0.7047 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 A24 mock treatment 828380.0 -245000.0 -1.19 822250.0 -147000.0 -0.87 1007610.0 -45630.9375 -0.261350848702599 -1.345 -0.8949 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B01 compound treatment 734330.0 -339000.0 -1.65 780000.0 -189000.0 -1.12 765130.0 -288110.9375 -1.65015321099038 -2.5572 -0.9861 2125367 Peakdale2_000023 Cc1nc(NC2CC2)cc(n1)c3cncc(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B02 compound treatment 789240.0 -284000.0 -1.39 876320.0 -92800.0 -0.55 831010.0 -222230.9375 -1.27282601028303 -1.8537 -0.9453 2125368 Peakdale2_000024 C1CN(CCO1)c2cc(nc(n2)c3ccccc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B03 compound treatment 909320.0 -164000.0 -0.8 861680.0 -107000.0 -0.64 946350.0 -106890.9375 -0.6122170344241 -1.1839 -0.9928 2125369 Peakdale2_000025 Cc1ccc(cc1)c2cnn(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B04 compound treatment 811780.0 -261000.0 -1.28 766250.0 -203000.0 -1.21 753660.0 -299580.9375 -1.71584754906132 -2.4238 -0.9873 2125370 Peakdale2_000026 CC(Nc1cc(nc(n1)c2ccccc2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B05 compound treatment 958940.0 -114000.0 -0.56 1007940.0 38800.0 0.23 1056430.0 3189.0625 0.0182653312994201 -0.1777 -0.2947 2125371 Peakdale2_000027 C(c1ccccc1)n2cc(cn2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B06 compound treatment 883310.0 -190000.0 -0.93 886620.0 -82500.0 -0.49 849030.0 -204210.9375 -1.16961659685336 -1.4934 -0.9508 2125372 Peakdale2_000028 Clc1ccc(CNc2cc(nc(n2)c3cccnc3)c4cccnc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B07 compound treatment 520320.0 -553000.0 -2.7 495910.0 -473000.0 -2.81 491310.0 -561930.9375 -3.21845518575795 -5.0417 -0.9971 2125373 Peakdale2_000029 O=C(N1CCCC1)c2ccc(nc2)c3cnn(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B08 compound treatment 533710.0 -539000.0 -2.63 809660.0 -159000.0 -0.95 850560.0 -202680.9375 -1.16085353344895 -2.7388 -0.9035 2125374 Peakdale2_000030 Clc1ccc(CNc2cc(nc(n2)c3ccncc3)c4cccnc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B09 compound treatment 1048890.0 -24000.0 -0.12 945200.0 -23900.0 -0.14 1014930.0 -38310.9375 -0.21942560417956 -0.2766 -0.965 2123860 Peakdale2_000031 CCCN1CCC(CC1)N(C2CC2)C(=O)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B10 compound treatment 1002560.0 -70400.0 -0.34 912690.0 -56400.0 -0.34 979930.0 -73310.9375 -0.419887838920868 -0.6347 -0.9947 2125375 Peakdale2_000032 Cc1nc(NCC=C)cc(n1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B11 compound treatment 1026020.0 -46900.0 -0.23 913780.0 -55300.0 -0.33 983730.0 -69510.9375 -0.398123367720383 -0.5522 -0.9772 2125376 Peakdale2_000033 Cc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B12 compound treatment 999210.0 -73700.0 -0.36 1034410.0 65300.0 0.39 1015110.0 -38130.9375 -0.218394655543747 -0.1099 -0.1919 2125377 Peakdale2_000034 Cc1nc(NC2CCCCC2)cc(n1)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B13 compound treatment 742150.0 -331000.0 -1.62 849440.0 -120000.0 -0.71 840210.0 -213030.9375 -1.22013308000817 -2.0484 -0.9543 2125378 Peakdale2_000035 Brc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B14 compound treatment 107100.0 -966000.0 -4.72 180440.0 -789000.0 -4.69 253760.0 -799480.9375 -4.57902101040932 -8.0759 -0.9999 2125379 Peakdale2_000036 CN1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B15 compound treatment 758290.0 -315000.0 -1.54 772540.0 -197000.0 -1.17 868420.0 -184820.9375 -1.05856051880668 -2.1736 -0.987 2125380 Peakdale2_000037 OC1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B16 compound treatment 759200.0 -314000.0 -1.53 798110.0 -171000.0 -1.02 966430.0 -86810.9375 -0.497208986606801 -1.7592 -0.9232 2125381 Peakdale2_000038 C=CCNc1cc(nc(n1)c2cccnc2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B17 compound treatment 241400.0 -832000.0 -4.06 324560.0 -645000.0 -3.83 401440.0 -651800.9375 -3.73318492964942 -6.7139 -0.9994 2125382 Peakdale2_000039 CN1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B18 compound treatment 1018210.0 -54700.0 -0.27 1064020.0 94900.0 0.56 1033960.0 -19280.9375 -0.1104314234045 0.1077 0.1698 2124445 Peakdale2_000040 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCN(Cc3cccc(Cl)n3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B19 compound treatment 963160.0 -110000.0 -0.54 885240.0 -83900.0 -0.5 1078400.0 25159.0625 0.14409833979275 -0.5145 -0.6892 2124194 Peakdale2_000041 Cc1ccc(cc1)S(=O)(=O)N(C2CC2)C3CCN(Cc4ccccc4)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B20 compound treatment 1026900.0 -46000.0 -0.22 1001040.0 31900.0 0.19 1043400.0 -9840.9375 -0.0563638949485583 -0.0528 -0.1763 2125383 Peakdale2_000042 Cc1nc(cc(n1)c2ccc(F)cc2)N3CCC4(CC3)OCCO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B21 compound treatment 918080.0 -155000.0 -0.76 855550.0 -114000.0 -0.68 1009190.0 -44050.9375 -0.252301410677134 -0.9724 -0.9305 2125384 Peakdale2_000043 Cc1nc(NCc2ccccc2)cc(n1)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B22 compound treatment 966490.0 -106000.0 -0.52 938720.0 -30400.0 -0.18 1048890.0 -4350.9375 -0.0249199615562789 -0.419 -0.7603 2125385 Peakdale2_000044 CN1CCN(CC1)c2cc(nc(C)n2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B23 mock treatment 960200.0 -113000.0 -0.55 981060.0 11900.0 0.07 1006830.0 -46410.9375 -0.265818292791119 -0.4305 -0.6992 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 B24 mock treatment 953310.0 -120000.0 -0.58 892110.0 -77000.0 -0.46 1060990.0 7749.0625 0.0443826967400019 -0.5762 -0.7747 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C01 compound treatment 959730.0 -113000.0 -0.55 889410.0 -79700.0 -0.47 868820.0 -184420.9375 -1.0562695218382 -1.2028 -0.9375 2125386 Peakdale2_000045 Clc1ccc(cc1)c2cnc(NCCC#N)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C02 compound treatment 968120.0 -105000.0 -0.51 917440.0 -51700.0 -0.31 975370.0 -77870.9375 -0.44600520436145 -0.7306 -0.9801 2125387 Peakdale2_000046 CCNC(=O)Nc1ccccc1c2cnn(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C03 compound treatment 744970.0 -328000.0 -1.6 735150.0 -234000.0 -1.39 788730.0 -264510.9375 -1.51498438985053 -2.6031 -0.9983 2125388 Peakdale2_000047 COCCNc1ncc(cn1)c2cc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C04 compound treatment 809480.0 -263000.0 -1.29 780390.0 -189000.0 -1.12 768500.0 -284740.9375 -1.630851561531 -2.3327 -0.9879 2125389 Peakdale2_000048 Cc1cnc(CNc2ncc(cn2)c3ccc(F)cc3)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C05 compound treatment 853220.0 -220000.0 -1.07 854080.0 -115000.0 -0.68 994880.0 -58360.9375 -0.334261827224223 -1.2077 -0.9177 2125390 Peakdale2_000049 C(Nc1ncc(cn1)c2cccs2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C06 compound treatment 863200.0 -210000.0 -1.02 892340.0 -76800.0 -0.46 953610.0 -99630.9375 -0.570635439446331 -1.1847 -0.9413 2125391 Peakdale2_000050 Fc1ccc(cc1)c2cnc(nc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C07 compound treatment 993120.0 -79800.0 -0.39 1040020.0 70900.0 0.42 1019050.0 -34190.9375 -0.195828335404297 -0.0948 -0.1562 2125392 Peakdale2_000051 Clc1ccc(cc1)c2cnc(nc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C08 compound treatment 917050.0 -156000.0 -0.76 932640.0 -36500.0 -0.22 930880.0 -122360.9375 -0.700821342179758 -0.9696 -0.9169 2125393 Peakdale2_000052 C(Nc1ncc(cn1)c2ccccc2)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C09 compound treatment 854080.0 -219000.0 -1.07 928920.0 -40200.0 -0.24 905940.0 -147300.9375 -0.843665003163993 -1.2425 -0.8985 2125394 Peakdale2_000053 COc1ccc(cc1)c2cnc(NCC=C)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C10 compound treatment 1023200.0 -49700.0 -0.24 1024320.0 55200.0 0.33 1030820.0 -22420.9375 -0.128415749607006 -0.0249 -0.0582 2125395 Peakdale2_000054 Fc1ccc(cc1)c2cnc(NC3CCCCC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C11 compound treatment 994810.0 -78100.0 -0.38 1012050.0 42900.0 0.26 1061210.0 7969.0625 0.0456427450726616 -0.0466 -0.1011 2125396 Peakdale2_000055 Cc1ccc(cc1)c2cnc(NCc3ccccc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C12 compound treatment 943280.0 -130000.0 -0.63 938830.0 -30300.0 -0.18 916010.0 -137230.9375 -0.785989154482708 -0.9235 -0.9006 2125397 Peakdale2_000056 CCN(CC)c1cc(nc(C)n1)c2cncc(c2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C13 compound treatment 184170.0 -889000.0 -4.34 203680.0 -765000.0 -4.55 97670.0 -955570.9375 -5.47302530243134 -8.2949 -0.9948 2125398 Peakdale2_000057 COc1ccc(cc1)c2cnc(nc2)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C14 compound treatment 863110.0 -210000.0 -1.03 841560.0 -128000.0 -0.76 986720.0 -66520.9375 -0.380998165381054 -1.2498 -0.939 2125399 Peakdale2_000058 Cc1nc(cc(n1)c2cncc(c2)c3ccc(F)cc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C15 compound treatment 1004920.0 -68000.0 -0.33 991840.0 22700.0 0.14 948820.0 -104420.9375 -0.598070128143785 -0.4592 -0.6584 2125400 Peakdale2_000059 CC(Nc1ncc(cn1)c2cccs2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C16 compound treatment 1105300.0 32400.0 0.16 944400.0 -24700.0 -0.15 1025990.0 -27250.9375 -0.156079538001306 -0.0837 -0.3141 2125401 Peakdale2_000060 CN(Cc1ccccc1)c2cc(nc(C)n2)c3cncc(c3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C17 compound treatment 793540.0 -279000.0 -1.37 729440.0 -240000.0 -1.43 828960.0 -224280.9375 -1.28456736974645 -2.3527 -0.9991 2125402 Peakdale2_000061 Cc1ccc(cc1)c2cnc(NC3CC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C18 compound treatment 696360.0 -377000.0 -1.84 704110.0 -265000.0 -1.58 765730.0 -287510.9375 -1.64671671553767 -2.9228 -0.9978 2125403 Peakdale2_000062 CN1CCN(CC1)c2cc(nc(C)n2)c3cncc(c3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C19 compound treatment 1051580.0 -21400.0 -0.1 1011880.0 42800.0 0.25 1122800.0 69559.0625 0.398399003293152 0.3166 0.6541 2125404 Peakdale2_000063 Cn1cc(cn1)c2ccccc2NC(=O)c3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C20 compound treatment 833040.0 -240000.0 -1.17 818570.0 -151000.0 -0.9 917670.0 -135570.9375 -0.776481517063549 -1.6419 -0.9851 2125405 Peakdale2_000064 Cc1ccc(cc1)c2cncc(c2)c3cc(NCc4ccco4)nc(C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C21 compound treatment 1075770.0 2840.0 0.01 904930.0 -64200.0 -0.38 1088380.0 35139.0625 0.201258714156129 -0.0962 -0.2228 2125406 Peakdale2_000065 CC(C)CC(=O)Nc1ccccc1c2cnn(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C22 compound treatment 1004060.0 -68900.0 -0.34 890320.0 -78800.0 -0.47 968750.0 -84490.9375 -0.483921204189663 -0.7442 -0.9883 2125407 Peakdale2_000066 Cc1ccc(cc1)c2cncc(c2)c3cc(NCc4ccc(Cl)cc4)nc(C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C23 mock treatment 953190.0 -120000.0 -0.59 1000240.0 31100.0 0.19 1122080.0 68839.0625 0.394275208749902 -0.0033 -0.0045 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 C24 mock treatment 881800.0 -191000.0 -0.93 863000.0 -106000.0 -0.63 981400.0 -71840.9375 -0.411468425061733 -1.1411 -0.951 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D01 compound treatment 823600.0 -249000.0 -1.22 800210.0 -169000.0 -1.0 745960.0 -307280.9375 -1.75994924070441 -2.2994 -0.9725 2125408 Peakdale2_000067 Cc1nc(NC2CC2)cc(n1)c3cncc(c3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D02 compound treatment 848160.0 -225000.0 -1.1 839950.0 -129000.0 -0.77 813610.0 -239630.9375 -1.37248437841156 -1.8699 -0.9748 2125409 Peakdale2_000068 C1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D03 compound treatment 989920.0 -83000.0 -0.41 947630.0 -21500.0 -0.13 942800.0 -110440.9375 -0.63254963251929 -0.6732 -0.8832 2125410 Peakdale2_000069 Cc1ccc(cc1)c2cnn(CCO)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D04 compound treatment 710600.0 -362000.0 -1.77 781530.0 -188000.0 -1.12 717470.0 -335770.9375 -1.92312549978383 -2.7765 -0.9769 2125411 Peakdale2_000070 Clc1ccc(CNc2cc(nc(n2)c3ccccc3)c4cccnc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D05 compound treatment 931640.0 -141000.0 -0.69 863110.0 -106000.0 -0.63 858660.0 -194580.9375 -1.11446084483739 -1.406 -0.9665 2123519 Peakdale2_000071 COc1cccc(OC)c1CN2CCC(CC2)N(C)C(=O)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D06 compound treatment 854170.0 -219000.0 -1.07 942340.0 -26800.0 -0.16 845850.0 -207390.9375 -1.18783002275271 -1.3948 -0.8686 2125412 Peakdale2_000072 C1CC1Nc2cc(nc(n2)c3cccnc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D07 compound treatment 959300.0 -114000.0 -0.56 997220.0 28100.0 0.17 987140.0 -66100.9375 -0.378592618564158 -0.4427 -0.6393 2125413 Peakdale2_000073 O=C(NCc1ccccc1)c2ccc(nc2)c3cnn(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D08 compound treatment 800540.0 -272000.0 -1.33 788590.0 -181000.0 -1.07 881120.0 -172120.9375 -0.985821365057686 -1.9574 -0.9917 2125414 Peakdale2_000074 C1CC1Nc2cc(nc(n2)c3ccncc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D09 compound treatment 1011710.0 -61200.0 -0.3 968690.0 -434.0 0.0 1120800.0 67559.0625 0.386944018450792 0.0492 0.1006 2125415 Peakdale2_000075 Clc1ccc(CNC(=O)c2ccc(nc2)c3cnn(c3)c4ccc(Cl)cc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D10 compound treatment 1040960.0 -32000.0 -0.16 931790.0 -37300.0 -0.22 974560.0 -78680.9375 -0.450644473222606 -0.4785 -0.9096 2125416 Peakdale2_000076 CN1CCN(CC1)c2cc(nc(C)n2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D11 compound treatment 1086110.0 13200.0 0.06 952930.0 -16200.0 -0.1 1116640.0 63399.0625 0.363117649978682 0.1912 0.5017 2125417 Peakdale2_000077 Cc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D12 compound treatment 1012060.0 -60900.0 -0.3 939000.0 -30100.0 -0.18 949780.0 -103460.9375 -0.592571735419452 -0.6173 -0.8988 2125418 Peakdale2_000078 Cc1nc(NC2CC2)cc(n1)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D13 compound treatment 937520.0 -135000.0 -0.66 1144540.0 175000.0 1.04 1221600.0 168359.0625 0.964275254505759 0.777 0.4958 2125419 Peakdale2_000079 CC(C)c1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D14 compound treatment 734120.0 -339000.0 -1.66 723550.0 -246000.0 -1.46 914600.0 -138640.9375 -0.794064918796572 -2.2573 -0.9622 2125420 Peakdale2_000080 C(Nc1cc(nc(n1)c2ccccc2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D15 compound treatment 906730.0 -166000.0 -0.81 918030.0 -51100.0 -0.3 1110110.0 56869.0625 0.325717124468375 -0.4562 -0.4926 2125421 Peakdale2_000081 C(Nc1cc(nc(n1)c2cccnc2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D16 compound treatment 933240.0 -140000.0 -0.68 817120.0 -152000.0 -0.9 1045860.0 -7380.9375 -0.042274263592455 -0.9403 -0.8296 2125422 Peakdale2_000082 C(Nc1cc(nc(n1)c2cccnc2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D17 compound treatment 478400.0 -595000.0 -2.9 545620.0 -424000.0 -2.52 940080.0 -113160.9375 -0.6481284119049 -3.5053 -0.8991 2125423 Peakdale2_000083 OC1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D18 compound treatment 360510.0 -712000.0 -3.48 391840.0 -577000.0 -3.43 492500.0 -560740.9375 -3.21163946977675 -5.8458 -0.9994 2125424 Peakdale2_000084 CC(Nc1cc(nc(n1)c2ccncc2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D19 compound treatment 1012550.0 -60400.0 -0.3 1051610.0 82500.0 0.49 1131360.0 78119.0625 0.447426338418455 0.3712 0.5109 2125425 Peakdale2_000085 Cc1nc(cc(n1)c2cccnc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D20 compound treatment 1001440.0 -71500.0 -0.35 888580.0 -80500.0 -0.48 911010.0 -142230.9375 -0.814626616588609 -0.9485 -0.9415 2125426 Peakdale2_000086 CCN(CC)c1cc(nc(C)n1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D21 compound treatment 889650.0 -183000.0 -0.9 846000.0 -123000.0 -0.73 1112530.0 59289.0625 0.339577656127631 -0.7437 -0.6169 2125427 Peakdale2_000087 Cc1nc(NCc2ccco2)cc(n1)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D22 compound treatment 1023840.0 -49100.0 -0.24 940900.0 -28200.0 -0.17 1056640.0 3399.0625 0.0194681047078679 -0.2241 -0.764 2125428 Peakdale2_000088 Cc1nc(cc(n1)c2ccc(F)cc2)N3CCC(O)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D23 mock treatment 990310.0 -82600.0 -0.4 947580.0 -21500.0 -0.13 986470.0 -66770.9375 -0.382430038486349 -0.5278 -0.925 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 D24 mock treatment 998850.0 -74100.0 -0.36 905280.0 -63800.0 -0.38 1159330.0 106089.0625 0.607624301438866 -0.0774 -0.0964 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E01 compound treatment 950320.0 -123000.0 -0.6 925690.0 -43400.0 -0.26 910330.0 -142910.9375 -0.818521311435012 -0.9676 -0.9244 2125429 Peakdale2_000089 Cc1ccc(cc1)c2cnc(NCc3cnc(C)cn3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E02 compound treatment 906330.0 -167000.0 -0.81 824030.0 -145000.0 -0.86 833240.0 -220000.9375 -1.2600537021838 -1.6956 -0.9798 2125430 Peakdale2_000090 Cc1nc(cc(n1)c2cncc(Br)c2)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E03 compound treatment 959400.0 -114000.0 -0.55 903320.0 -65800.0 -0.39 916170.0 -137070.9375 -0.785072755695319 -0.9994 -0.963 2125431 Peakdale2_000091 Cc1ccc(cc1)c2cnc(nc2)N3CCC4(CC3)OCCO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E04 compound treatment 664770.0 -408000.0 -1.99 668910.0 -300000.0 -1.79 699360.0 -353880.9375 -2.02685038753141 -3.3523 -0.9985 2125432 Peakdale2_000092 Cc1cnc(CNc2ncc(cn2)c3ccccc3)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E05 compound treatment 1063280.0 -9650.0 -0.05 923480.0 -45600.0 -0.27 927470.0 -125770.9375 -0.720352091335983 -0.5998 -0.7778 2125433 Peakdale2_000093 Cc1ccc(cc1)c2cnc(nc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E06 compound treatment 1225850.0 153000.0 0.75 1030880.0 61800.0 0.37 1041240.0 -12000.9375 -0.0687352785783076 0.6037 0.7227 2125434 Peakdale2_000094 CN(Cc1ccccc1)c2ncc(cn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E07 compound treatment 1074880.0 1950.0 0.01 967300.0 -1820.0 -0.01 1146920.0 93679.0625 0.536546120492019 0.309 0.5757 2125435 Peakdale2_000095 C1CCN(CC1)c2ncc(cn2)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E08 compound treatment 855570.0 -217000.0 -1.06 872930.0 -96200.0 -0.57 882050.0 -171190.9375 -0.980494797105989 -1.5095 -0.9711 2125436 Peakdale2_000096 Fc1ccc(cc1)c2cnc(nc2)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E09 compound treatment 1067880.0 -5050.0 -0.02 950080.0 -19000.0 -0.11 992000.0 -61240.9375 -0.350757005397222 -0.2821 -0.7638 2125437 Peakdale2_000097 Clc1ccc(cc1)c2cnc(NCC=C)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E10 compound treatment 1085290.0 12400.0 0.06 905180.0 -63900.0 -0.38 924020.0 -129220.9375 -0.740111940189054 -0.612 -0.7336 2125438 Peakdale2_000098 C1CCC(CC1)Nc2ncc(cn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E11 compound treatment 1127720.0 54800.0 0.27 1012380.0 43300.0 0.26 1323690.0 270449.0625 1.54899495578405 1.1974 0.7517 2125439 Peakdale2_000099 COc1ccc(cc1)c2cnc(NCc3ccccc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E12 compound treatment 891970.0 -181000.0 -0.88 854890.0 -114000.0 -0.68 1038330.0 -14910.9375 -0.0854022815239421 -0.952 -0.8513 2125440 Peakdale2_000100 Cc1ccc(cc1)c2cncc(c2)c3cc(NCc4ccncc4)nc(C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E13 compound treatment 1134240.0 61300.0 0.3 1295000.0 326000.0 1.94 1046140.0 -7100.9375 -0.0406705657145245 1.2683 0.6467 2122582 Peakdale2_000101 COc1cccc(CCN2CCCC2)c1NC(=O)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E14 compound treatment 874560.0 -198000.0 -0.97 886890.0 -82200.0 -0.49 924560.0 -128680.9375 -0.737019094281617 -1.2674 -0.9659 2125441 Peakdale2_000102 Cc1ccc(cc1)c2cncc(c2)c3cc(nc(C)n3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E15 compound treatment 1064000.0 -8930.0 -0.04 996170.0 27000.0 0.16 1267200.0 213959.0625 1.22544890891158 0.7752 0.6268 2125442 Peakdale2_000103 COc1ccc(cc1)c2cnc(NCc3ccc(Cl)cc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E16 compound treatment 1007110.0 -65800.0 -0.32 893730.0 -75400.0 -0.45 1133780.0 80539.0625 0.461286870077711 -0.1782 -0.2478 2125443 Peakdale2_000104 Cc1ccc(cc1)c2cncc(c2)c3cc(NCC=C)nc(C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E17 compound treatment 696550.0 -376000.0 -1.84 614580.0 -355000.0 -2.11 785340.0 -267900.9375 -1.53440058915833 -3.1648 -0.9919 2125444 Peakdale2_000105 COc1ccc(cc1)c2cnc(NC3CC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E18 compound treatment 878720.0 -194000.0 -0.95 712380.0 -257000.0 -1.53 897320.0 -155920.9375 -0.893035987834567 -1.9449 -0.969 2125445 Peakdale2_000106 Cc1nc(cc(n1)c2cncc(c2)c3cccs3)N4CCC(O)CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E19 compound treatment 1189720.0 117000.0 0.57 1065500.0 96400.0 0.57 1127930.0 74689.0625 0.427781039413807 0.9073 0.9917 2125446 Peakdale2_000107 Cn1cc(cn1)c2ccccc2NC(=O)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E20 compound treatment 545620.0 -527000.0 -2.58 509210.0 -460000.0 -2.73 575940.0 -477300.9375 -2.73373750215347 -4.6448 -0.9996 2125447 Peakdale2_000108 Cc1nc(NCc2ccco2)cc(n1)c3cncc(c3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E21 compound treatment 1050970.0 -22000.0 -0.11 957200.0 -11900.0 -0.07 1099430.0 46189.0625 0.26454750541017 0.0498 0.1694 2125448 Peakdale2_000109 Cn1cc(cn1)c2ccccc2NC(=O)Cc3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E22 compound treatment 921320.0 -152000.0 -0.74 831910.0 -137000.0 -0.82 1000020.0 -53220.9375 -0.304822516179357 -1.0748 -0.9399 2125449 Peakdale2_000110 Cc1nc(NCc2ccc(Cl)cc2)cc(n1)c3cncc(c3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E23 mock treatment 1049320.0 -23600.0 -0.12 910100.0 -59000.0 -0.35 1064650.0 11409.0625 0.0653453190015216 -0.2315 -0.6171 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 E24 mock treatment 1043490.0 -29400.0 -0.14 1097780.0 129000.0 0.77 1029620.0 -23620.9375 -0.135288740512422 0.2805 0.3551 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F01 compound treatment 988610.0 -84300.0 -0.41 867410.0 -102000.0 -0.6 965600.0 -87640.9375 -0.50196280531638 -0.8769 -0.9881 2125450 Peakdale2_000111 Cc1cc(C)cc(NC(=O)N2CCNC(=O)CC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F02 compound treatment 985920.0 -87000.0 -0.43 943540.0 -25600.0 -0.15 846720.0 -206520.9375 -1.18284710434629 -1.0162 -0.8026 2125451 Peakdale2_000112 CN(Cc1ccccc1)c2cc(nc(n2)c3ccccc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F03 compound treatment 983050.0 -89900.0 -0.44 948320.0 -20800.0 -0.12 947880.0 -105360.9375 -0.603453971019694 -0.6734 -0.8901 2125452 Peakdale2_000113 C(c1ccccc1)n2cc(cn2)c3ccncn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F04 compound treatment 887690.0 -185000.0 -0.91 798900.0 -170000.0 -1.01 857030.0 -196210.9375 -1.12379665748392 -1.7558 -0.9961 2125453 Peakdale2_000114 C1CC1Nc2cc(nc(n2)c3ccccc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F05 compound treatment 1098810.0 25900.0 0.13 1010780.0 41700.0 0.25 969690.0 -83550.9375 -0.478537361313753 -0.0603 -0.1089 2125454 Peakdale2_000115 CN(Cc1ccccc1)C(=O)c2ccc(nc2)c3cnn(C)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F06 compound treatment 671230.0 -402000.0 -1.96 601600.0 -368000.0 -2.19 642330.0 -410910.9375 -2.35348928031131 -3.7537 -0.9973 2125455 Peakdale2_000116 CCN(CC)c1cc(nc(n1)c2ccncc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F07 compound treatment 1072040.0 -893.0 0.0 1280580.0 311000.0 1.85 1216160.0 162919.0625 0.933117695734539 1.6055 0.7742 2125456 Peakdale2_000117 Clc1ccc(CNC(=O)c2ccc(nc2)c3cnn(c3)c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F08 compound treatment 1079970.0 7040.0 0.03 895280.0 -73800.0 -0.44 962670.0 -90570.9375 -0.518744358110439 -0.5332 -0.7835 2125457 Peakdale2_000118 Cc1nc(NCCC#N)cc(n1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F09 compound treatment 1074770.0 1840.0 0.01 946640.0 -22500.0 -0.13 1006580.0 -46660.9375 -0.267250165896414 -0.2263 -0.757 2125458 Peakdale2_000119 Clc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)NC4CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F10 compound treatment 1017930.0 -55000.0 -0.27 937060.0 -32100.0 -0.19 959680.0 -93560.9375 -0.535869560449767 -0.5746 -0.9134 2125459 Peakdale2_000120 Cc1nc(NCc2ccccc2)cc(n1)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F11 compound treatment 1044120.0 -28800.0 -0.14 909800.0 -59300.0 -0.35 1007480.0 -45760.9375 -0.262095422717352 -0.4363 -0.9454 2125460 Peakdale2_000121 Cc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)NCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F12 compound treatment 921940.0 -151000.0 -0.74 828480.0 -141000.0 -0.84 849780.0 -203460.9375 -1.16532097753747 -1.5816 -0.9805 2125461 Peakdale2_000122 Cc1nc(NCCc2c[nH]c3ccccc23)cc(n1)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F13 compound treatment 1226810.0 154000.0 0.75 917550.0 -51600.0 -0.31 943610.0 -109630.9375 -0.627910363658134 -0.1055 -0.1028 2125462 Peakdale2_000123 CCN(CC)c1cc(nc(n1)c2cccnc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F14 compound treatment 905000.0 -168000.0 -0.82 805690.0 -163000.0 -0.97 1024320.0 -28920.9375 -0.165644450344677 -1.1305 -0.8813 2125463 Peakdale2_000124 CC(Nc1cc(nc(n1)c2ccccc2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F15 compound treatment 951810.0 -121000.0 -0.59 852820.0 -116000.0 -0.69 1217120.0 163879.0625 0.938616088458872 -0.1991 -0.1522 2125464 Peakdale2_000125 C1CC1Nc2cc(nc(n2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F16 compound treatment 1030560.0 -42400.0 -0.21 837500.0 -132000.0 -0.78 1126030.0 72789.0625 0.416898803813564 -0.3307 -0.3632 2125465 Peakdale2_000126 CC(Nc1cc(nc(n1)c2cccnc2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F17 compound treatment 943420.0 -130000.0 -0.63 860910.0 -108000.0 -0.64 997520.0 -55720.9375 -0.319141247232307 -0.9211 -0.9622 2125466 Peakdale2_000127 C(Nc1cc(nc(n1)c2ccncc2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F18 compound treatment 1199780.0 127000.0 0.62 1037200.0 68100.0 0.4 1071280.0 18039.0625 0.103318593753947 0.6512 0.8712 2125467 Peakdale2_000128 Clc1ccc(CNc2cc(nc(n2)c3ccncc3)c4ccncc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F19 compound treatment 1062940.0 -9990.0 -0.05 943270.0 -25900.0 -0.15 1266890.0 213649.0625 1.22367338626101 0.5895 0.4776 2125468 Peakdale2_000129 Cc1nc(cc(n1)c2cccnc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F20 compound treatment 1016640.0 -56300.0 -0.28 910480.0 -58600.0 -0.35 913950.0 -139290.9375 -0.797787788870339 -0.8207 -0.8989 2125469 Peakdale2_000130 Cc1nc(NCc2ccncc2)cc(n1)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F21 compound treatment 879210.0 -194000.0 -0.95 856040.0 -113000.0 -0.67 921280.0 -131960.9375 -0.755805269423088 -1.3711 -0.9897 2125470 Peakdale2_000131 Cc1nc(cc(n1)c2cccnc2)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F22 compound treatment 991040.0 -81900.0 -0.4 1029490.0 60400.0 0.36 1051680.0 -1560.9375 -0.00894025770118602 -0.0289 -0.0538 2125471 Peakdale2_000132 Cc1nc(NCc2ccccc2)cc(n1)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F23 mock treatment 1133980.0 61000.0 0.3 969050.0 -74.1 0.0 1048240.0 -5000.9375 -0.028642831630046 0.1554 0.5187 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 F24 mock treatment 965230.0 -108000.0 -0.53 950990.0 -18100.0 -0.11 1092380.0 39139.0625 0.224168683840849 -0.2366 -0.4066 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G01 compound treatment 995700.0 -77200.0 -0.38 883010.0 -86100.0 -0.51 954600.0 -98640.9375 -0.564965221949363 -0.8397 -0.987 2125472 Peakdale2_000133 Cc1cnc(CNc2ncc(cn2)c3ccc(Cl)cc3)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G02 compound treatment 996960.0 -76000.0 -0.37 805050.0 -164000.0 -0.98 911200.0 -142040.9375 -0.813538393028585 -1.2473 -0.9425 2125473 Peakdale2_000134 CC(Nc1cc(nc(C)n1)c2cncc(Br)c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G03 compound treatment 961830.0 -111000.0 -0.54 808480.0 -161000.0 -0.96 785490.0 -267750.9375 -1.53354146529515 -1.7503 -0.9278 2125474 Peakdale2_000135 Clc1ccc(cc1)c2cnc(nc2)N3CCC4(CC3)OCCO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G04 compound treatment 980330.0 -92600.0 -0.45 920230.0 -48900.0 -0.29 929770.0 -123470.9375 -0.707178858767268 -0.8374 -0.9425 2125475 Peakdale2_000136 COCCNc1ncc(cn1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G05 compound treatment 996260.0 -76700.0 -0.37 902520.0 -66600.0 -0.4 933720.0 -119520.9375 -0.684555263703606 -0.8402 -0.9601 2125476 Peakdale2_000137 COc1ccc(cc1)c2cnc(nc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G06 compound treatment 1114020.0 41100.0 0.2 921230.0 -47900.0 -0.28 960010.0 -93230.9375 -0.533979487950778 -0.3568 -0.5596 2125477 Peakdale2_000138 OCCCNc1ncc(cn1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G07 compound treatment 1083240.0 10300.0 0.05 1004500.0 35400.0 0.21 1077650.0 24409.0625 0.139802720476865 0.2312 0.8978 2125478 Peakdale2_000139 CN(Cc1ccccc1)c2ncc(cn2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G08 compound treatment 1086520.0 13600.0 0.07 967040.0 -2080.0 -0.01 1027430.0 -25810.9375 -0.147831948914807 -0.0542 -0.3334 2125479 Peakdale2_000140 Fc1ccc(cc1)c2cnc(NCCc3ccccc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G09 compound treatment 1100960.0 28000.0 0.14 880480.0 -88600.0 -0.53 970610.0 -82630.9375 -0.473268068286267 -0.4985 -0.6909 2125480 Peakdale2_000141 C=CCNc1ncc(cn1)c2cc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G10 compound treatment 951560.0 -121000.0 -0.59 823840.0 -145000.0 -0.86 855040.0 -198200.9375 -1.13519436740207 -1.4966 -0.9687 2125481 Peakdale2_000142 Fc1ccc(cc1)c2cnc(NC3CC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G11 compound treatment 1081990.0 9060.0 0.04 1032710.0 63600.0 0.38 1286560.0 233319.0625 1.33633316218563 1.0154 0.7308 2125482 Peakdale2_000143 Clc1ccc(cc1)c2cnc(NCc3ccccc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G12 compound treatment 771010.0 -302000.0 -1.48 707150.0 -262000.0 -1.56 831570.0 -221670.9375 -1.26961861452717 -2.4841 -0.9964 2125483 Peakdale2_000144 Cc1nc(NCc2ccncc2)cc(n1)c3cncc(c3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G13 compound treatment 1384910.0 312000.0 1.52 1327310.0 358000.0 2.13 1098410.0 45169.0625 0.258705463140566 2.2591 0.8584 2125484 Peakdale2_000145 Cc1ccc(cc1)c2cnc(NCCc3ccccc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G14 compound treatment 1163550.0 90600.0 0.44 920530.0 -48600.0 -0.29 963950.0 -89290.9375 -0.511413167811328 -0.2065 -0.2807 2123560 Peakdale2_000146 CC(=O)N1CCc2ccc(cc12)N(C3CCN(Cc4ccccc4)CC3)C(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G15 compound treatment 1000820.0 -72100.0 -0.35 953230.0 -15900.0 -0.09 1022140.0 -31100.9375 -0.17813038382285 -0.3608 -0.8888 2125485 Peakdale2_000147 Clc1ccc(CNc2ncc(cn2)c3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G16 compound treatment 381760.0 -691000.0 -3.38 329200.0 -640000.0 -3.81 368560.0 -684680.9375 -3.92150488045783 -6.4108 -0.998 2125486 Peakdale2_000148 Cc1nc(NCC=C)cc(n1)c2cncc(c2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G17 compound treatment 977320.0 -95600.0 -0.47 813950.0 -155000.0 -0.92 1087280.0 34039.0625 0.19495847249283 -0.6899 -0.6555 2125487 Peakdale2_000149 FC(F)(F)Oc1ccc(cc1)c2cnc(NC3CC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G18 compound treatment 1057120.0 -15800.0 -0.08 975220.0 6100.0 0.04 1055750.0 2509.0625 0.0143706364530175 -0.0154 -0.1777 2125488 Peakdale2_000150 Cc1nc(cc(n1)c2cncc(c2)c3ccccc3)N4CCC(O)CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G19 compound treatment 1371480.0 299000.0 1.46 1068770.0 99600.0 0.59 1086360.0 33119.0625 0.189689179465344 1.2938 0.8159 2125489 Peakdale2_000151 Cn1cc(cn1)c2ccccc2NC(=O)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G20 compound treatment 918900.0 -154000.0 -0.75 871140.0 -98000.0 -0.58 1060700.0 7459.0625 0.0427217239378597 -0.7462 -0.7833 2125490 Peakdale2_000152 Cc1nc(NCc2ccco2)cc(n1)c3cncc(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G21 compound treatment 1133440.0 60500.0 0.3 1003810.0 34700.0 0.21 1149000.0 95759.0625 0.548459304728074 0.6064 0.924 2125491 Peakdale2_000153 Cn1cc(cn1)c2ccccc2NC(=O)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G22 compound treatment 948980.0 -124000.0 -0.61 838530.0 -131000.0 -0.78 941020.0 -112220.9375 -0.642744569028991 -1.1691 -0.9941 2125492 Peakdale2_000154 Cc1nc(NCc2ccc(Cl)cc2)cc(n1)c3cncc(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G23 mock treatment 1060920.0 -12000.0 -0.06 893150.0 -76000.0 -0.45 985090.0 -68150.9375 -0.390333978027578 -0.5201 -0.8669 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 G24 mock treatment 1163860.0 90900.0 0.44 1082660.0 114000.0 0.68 1125840.0 72599.0625 0.41581058025354 0.8864 0.9752 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H01 compound treatment 825950.0 -247000.0 -1.21 835710.0 -133000.0 -0.79 783560.0 -269680.9375 -1.54459552566803 -2.0465 -0.9678 2125493 Peakdale2_000155 Cn1cc(cn1)c2cnc3ccccc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H02 compound treatment 982820.0 -90100.0 -0.44 935260.0 -33900.0 -0.2 945390.0 -107850.9375 -0.617715427148433 -0.7271 -0.9264 2125494 Peakdale2_000156 C=CCNc1cc(nc(n1)c2ccccc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H03 compound treatment 998300.0 -74600.0 -0.36 891880.0 -77200.0 -0.46 937360.0 -115880.9375 -0.66370719129051 -0.8589 -0.9698 2125495 Peakdale2_000157 Cn1cc(cn1)c2ccncn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H04 compound treatment 726200.0 -347000.0 -1.69 738430.0 -231000.0 -1.37 812390.0 -240850.9375 -1.3794719191654 -2.5665 -0.9949 2125496 Peakdale2_000158 CCN(CC)c1cc(nc(n1)c2cccnc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H05 compound treatment 1156860.0 83900.0 0.41 980420.0 11300.0 0.07 995000.0 -58240.9375 -0.333574528133682 0.0829 0.1556 2125497 Peakdale2_000159 Cn1cc(cn1)c2ccc(cn2)C(=O)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H06 compound treatment 1040340.0 -32600.0 -0.16 985570.0 16400.0 0.1 1036480.0 -16760.9375 -0.0959981425031256 -0.0909 -0.4327 2125498 Peakdale2_000160 C1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H07 compound treatment 1044510.0 -28400.0 -0.14 953470.0 -15700.0 -0.09 1015590.0 -37650.9375 -0.215645459181581 -0.2584 -0.9471 2125499 Peakdale2_000161 O=C(NC1CC1)c2ccc(nc2)c3cnn(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H08 compound treatment 1343090.0 270000.0 1.32 1038720.0 69600.0 0.41 993840.0 -59400.9375 -0.340218419342251 0.8046 0.5648 2125500 Peakdale2_000162 COCCNc1cc(nc(C)n1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H09 compound treatment 1338820.0 266000.0 1.3 948360.0 -20800.0 -0.12 992220.0 -61020.9375 -0.349496957064563 0.477 0.3531 2125501 Peakdale2_000163 CN(Cc1ccccc1)C(=O)c2ccc(nc2)c3cnn(c3)c4ccc(F)cc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H10 compound treatment 1170560.0 97600.0 0.48 877280.0 -91800.0 -0.55 967170.0 -86070.9375 -0.492970642215127 -0.3246 -0.3701 2125502 Peakdale2_000164 Cc1nc(NCc2ccco2)cc(n1)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H11 compound treatment 1169920.0 97000.0 0.47 1105670.0 137000.0 0.81 1004930.0 -48310.9375 -0.276700528391362 0.5826 0.5945 2125503 Peakdale2_000165 Cc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)NCc4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H12 compound treatment 958600.0 -114000.0 -0.56 893990.0 -75100.0 -0.45 1066250.0 13009.0625 0.07450930687541 -0.5375 -0.7473 2125504 Peakdale2_000166 CCN(CC)c1cc(nc(n1)c2ccccc2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H13 compound treatment 1064390.0 -8540.0 -0.04 842690.0 -126000.0 -0.75 698770.0 -354470.9375 -2.0302296080599 -1.6303 -0.7529 2125505 Peakdale2_000167 C1CN(CCO1)c2cc(nc(n2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H14 compound treatment 1027850.0 -45100.0 -0.22 895690.0 -73400.0 -0.44 953230.0 -100010.9375 -0.57281188656638 -0.71 -0.9426 2125506 Peakdale2_000168 Clc1ccc(CNc2cc(nc(n2)c3ccccc3)c4ccncc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H15 compound treatment 1022910.0 -50000.0 -0.24 926460.0 -42700.0 -0.25 856060.0 -197180.9375 -1.12935232513246 -0.9396 -0.7943 2125507 Peakdale2_000169 CCN(CC)c1cc(nc(n1)c2ccncc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H16 compound treatment 962880.0 -110000.0 -0.54 795950.0 -173000.0 -1.03 1070480.0 17239.0625 0.0987365998170023 -0.848 -0.7273 2125508 Peakdale2_000170 C1CC1Nc2cc(nc(n2)c3cccnc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H17 compound treatment 1238890.0 166000.0 0.81 888390.0 -80700.0 -0.48 909680.0 -143560.9375 -0.822244181508779 -0.2838 -0.2269 2125509 Peakdale2_000171 CC(Nc1cc(nc(n1)c2ccncc2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H18 compound treatment 1141070.0 68100.0 0.33 753440.0 -216000.0 -1.28 875360.0 -177880.9375 -1.01881172140368 -1.1365 -0.6799 2125510 Peakdale2_000172 C1CC1Nc2cc(nc(n2)c3ccncc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H19 compound treatment 1098790.0 25900.0 0.13 989800.0 20700.0 0.12 999230.0 -54010.9375 -0.309347235192089 -0.0347 -0.0974 2125511 Peakdale2_000173 CN(Cc1ccccc1)c2cc(nc(C)n2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H20 compound treatment 1201620.0 129000.0 0.63 1045480.0 76400.0 0.45 1029960.0 -23280.9375 -0.133341393089221 0.5482 0.6966 2125512 Peakdale2_000174 Cc1nc(cc(n1)c2ccc(F)cc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H21 compound treatment 1041440.0 -31500.0 -0.15 889160.0 -80000.0 -0.48 957550.0 -95690.9375 -0.548069119306881 -0.6798 -0.9165 2125513 Peakdale2_000175 Cc1nc(NCCc2ccccc2)cc(n1)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H22 compound treatment 976550.0 -96400.0 -0.47 818990.0 -150000.0 -0.89 959920.0 -93320.9375 -0.534494962268684 -1.0959 -0.9595 2125514 Peakdale2_000176 Cc1nc(NCc2ccco2)cc(n1)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H23 mock treatment 1204800.0 132000.0 0.64 980070.0 10900.0 0.07 1034190.0 -19050.9375 -0.109114100147628 0.3466 0.5277 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 H24 mock treatment 1165760.0 92800.0 0.45 997470.0 28300.0 0.17 1128110.0 74869.0625 0.428811988049619 0.6067 0.9385 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I01 compound treatment 588090.0 -485000.0 -2.37 492270.0 -477000.0 -2.84 506820.0 -546420.9375 -3.12962177830545 -4.8117 -0.9937 2125515 Peakdale2_000177 Cc1cnc(CNc2ncc(cn2)c3cccs3)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I02 compound treatment 1018560.0 -54400.0 -0.27 906200.0 -62900.0 -0.37 999720.0 -53520.9375 -0.306540763905711 -0.5464 -0.9901 2125516 Peakdale2_000178 Cc1nc(NCc2ccc(Cl)cc2)cc(n1)c3cncc(Br)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I03 compound treatment 597090.0 -476000.0 -2.32 598180.0 -371000.0 -2.21 587920.0 -465320.9375 -2.66512214294773 -4.1545 -0.9967 2125517 Peakdale2_000179 C1COC2(CCN(CC2)c3ncc(cn3)c4cccs4)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I04 compound treatment 421770.0 -651000.0 -3.18 387230.0 -582000.0 -3.46 421990.0 -631250.9375 -3.61548496039417 -5.922 -0.9986 2125518 Peakdale2_000180 Fc1ccc(cc1)c2cnc(nc2)N3CCC4(CC3)OCCO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I05 compound treatment 1044050.0 -28900.0 -0.14 934930.0 -34200.0 -0.2 898500.0 -154740.9375 -0.886277546777574 -0.7106 -0.7722 2125519 Peakdale2_000181 Clc1ccc(cc1)c2cnc(nc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I06 compound treatment 1019380.0 -53600.0 -0.26 944910.0 -24200.0 -0.14 1005460.0 -47780.9375 -0.273664957408136 -0.3922 -0.9682 2125520 Peakdale2_000182 Fc1ccc(cc1)c2cnc(NCC=C)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I07 compound treatment 1036980.0 -36000.0 -0.18 923000.0 -46100.0 -0.27 998140.0 -55100.9375 -0.315590201931176 -0.442 -0.9745 2125521 Peakdale2_000183 CN(Cc1ccccc1)c2ncc(cn2)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I08 compound treatment 1132010.0 59100.0 0.29 1025340.0 56200.0 0.33 1041810.0 -11430.9375 -0.0654706078982349 0.3218 0.7209 2125522 Peakdale2_000184 C(Cc1ccccc1)Nc2ncc(cn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I09 compound treatment 923840.0 -149000.0 -0.73 795640.0 -173000.0 -1.03 805960.0 -247280.9375 -1.41629969543359 -1.8339 -0.9664 2125523 Peakdale2_000185 CN1CCN(CC1)c2ncc(cn2)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I10 compound treatment 901160.0 -172000.0 -0.84 822560.0 -147000.0 -0.87 819120.0 -234120.9375 -1.34092589517086 -1.7619 -0.9755 2125524 Peakdale2_000186 C1CC1Nc2ncc(cn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I11 compound treatment 1055460.0 -17500.0 -0.09 885690.0 -83400.0 -0.5 1005830.0 -47410.9375 -0.2715457852123 -0.4925 -0.861 2125525 Peakdale2_000187 Cc1ccc(cc1)c2cnc(NCc3ccco3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I12 compound treatment 870460.0 -202000.0 -0.99 721600.0 -248000.0 -1.47 910970.0 -142270.9375 -0.814855716285457 -1.8914 -0.9691 2125526 Peakdale2_000188 Cc1nc(NCc2ccncc2)cc(n1)c3cncc(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I13 compound treatment 1514400.0 441000.0 2.16 963870.0 -5250.0 -0.03 1040850.0 -12390.9375 -0.0709690006225679 1.1863 0.5496 2125527 Peakdale2_000189 C(Cc1ccccc1)Nc2ncc(cn2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I14 compound treatment 909280.0 -164000.0 -0.8 970750.0 1630.0 0.01 858880.0 -194360.9375 -1.11320079650473 -1.0988 -0.8016 2125528 Peakdale2_000190 Cc1nc(cc(n1)c2cncc(c2)c3ccccc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I15 compound treatment 1012520.0 -60400.0 -0.3 927400.0 -41700.0 -0.25 914790.0 -138450.9375 -0.792976695236548 -0.7715 -0.8749 2125529 Peakdale2_000191 Clc1ccc(CNc2ncc(cn2)c3cccs3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I16 compound treatment 893250.0 -180000.0 -0.88 735300.0 -234000.0 -1.39 780750.0 -272490.9375 -1.56068977937155 -2.2107 -0.9751 2125530 Peakdale2_000192 Cc1nc(NCC=C)cc(n1)c2cncc(c2)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I17 compound treatment 1000480.0 -72500.0 -0.35 789480.0 -180000.0 -1.07 972590.0 -80650.9375 -0.461927633292331 -1.0878 -0.8942 2125531 Peakdale2_000193 Clc1ccc(cc1)c2cnc(NC3CC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I18 compound treatment 985180.0 -87800.0 -0.43 820170.0 -149000.0 -0.89 931780.0 -121460.9375 -0.695666599000696 -1.1606 -0.963 2125532 Peakdale2_000194 Cc1nc(cc(n1)c2cncc(c2)c3ccc(F)cc3)N4CCC(O)CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I19 compound treatment 1181080.0 108000.0 0.53 933080.0 -36000.0 -0.21 1188100.0 134859.0625 0.772404258396221 0.6273 0.6533 2125533 Peakdale2_000195 Cn1cc(cn1)c2ccccc2NC(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I20 compound treatment 993820.0 -79100.0 -0.39 873280.0 -95800.0 -0.57 917360.0 -135880.9375 -0.778257039714115 -1.0015 -0.9638 2125534 Peakdale2_000196 Cc1nc(NCc2ccco2)cc(n1)c3cncc(c3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I21 compound treatment 1043440.0 -29500.0 -0.14 944810.0 -24300.0 -0.14 1031390.0 -21850.9375 -0.125151078926933 -0.2389 -0.9979 2125535 Peakdale2_000197 Cn1cc(cn1)c2ccccc2NC(=O)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I22 compound treatment 1213140.0 140000.0 0.69 902990.0 -66100.0 -0.39 931950.0 -121290.9375 -0.694692925289095 -0.2326 -0.2212 2125536 Peakdale2_000198 Cc1nc(NCc2ccc(Cl)cc2)cc(n1)c3cncc(c3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I23 mock treatment 1148160.0 75200.0 0.37 951740.0 -17400.0 -0.1 992080.0 -61160.9375 -0.350298806003528 -0.0497 -0.096 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 I24 mock treatment 1128800.0 55900.0 0.27 956920.0 -12200.0 -0.07 1092340.0 39099.0625 0.223939584144002 0.245 0.6797 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J01 compound treatment 825000.0 -248000.0 -1.21 738690.0 -230000.0 -1.37 710530.0 -342710.9375 -1.96287429718682 -2.6238 -0.978 2125537 Peakdale2_000199 Cn1cc(cn1)c2ccnc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J02 compound treatment 789390.0 -284000.0 -1.39 809400.0 -160000.0 -0.95 809360.0 -243880.9375 -1.39682622120158 -2.1547 -0.9863 2125538 Peakdale2_000200 CN1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J03 compound treatment 1332260.0 259000.0 1.27 1025000.0 55900.0 0.33 992680.0 -60560.9375 -0.34686231055082 0.7231 0.5336 2125539 Peakdale2_000201 OCCn1cc(cn1)c2ccncn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J04 compound treatment 897440.0 -175000.0 -0.86 939740.0 -29400.0 -0.17 874080.0 -179160.9375 -1.0261429117028 -1.1884 -0.8812 2125540 Peakdale2_000202 C1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J05 compound treatment 1190890.0 118000.0 0.58 1009620.0 40500.0 0.24 1008570.0 -44670.9375 -0.255852455978266 0.3241 0.4801 2123428 Peakdale2_000203 O=C(NCCc1ccccc1)c2ccc(CCN3CCCC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J06 compound treatment 1140760.0 67800.0 0.33 872340.0 -96800.0 -0.58 902440.0 -150800.9375 -0.863711226638124 -0.6396 -0.5871 2125541 Peakdale2_000204 CN(Cc1ccccc1)c2cc(nc(n2)c3ccncc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J07 compound treatment 999930.0 -73000.0 -0.36 881860.0 -87300.0 -0.52 906690.0 -146550.9375 -0.839369383848108 -0.9901 -0.9436 2123503 Peakdale2_000205 CCCN1CCC(CC1)N(C(=O)CC)c2ccc3[nH]c(cc3c2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J08 compound treatment 1113120.0 40200.0 0.2 981610.0 12500.0 0.07 1043840.0 -9400.9375 -0.053843798283239 0.1251 0.5775 2125542 Peakdale2_000206 CCN(CC)c1cc(nc(C)n1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J09 compound treatment 1071110.0 -1820.0 -0.01 955970.0 -13200.0 -0.08 1016550.0 -36690.9375 -0.210147066457248 -0.1716 -0.7648 2125543 Peakdale2_000207 Fc1ccc(c(F)c1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J10 compound treatment 865780.0 -207000.0 -1.01 817710.0 -151000.0 -0.9 825650.0 -227590.9375 -1.30352536966055 -1.8568 -0.9877 2125544 Peakdale2_000208 Cc1nc(cc(n1)c2ccncc2)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J11 compound treatment 1282100.0 209000.0 1.02 917130.0 -52000.0 -0.31 1088070.0 34829.0625 0.199483191505563 0.5267 0.4849 2125545 Peakdale2_000209 Cc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)NC4CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J12 compound treatment 853640.0 -219000.0 -1.07 732720.0 -236000.0 -1.41 996810.0 -56430.9375 -0.323207766851345 -1.6168 -0.8998 2125546 Peakdale2_000210 C1CN(CCO1)c2cc(nc(n2)c3ccccc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J13 compound treatment 1153470.0 80500.0 0.39 911690.0 -57400.0 -0.34 1093440.0 40199.0625 0.2302398258073 0.1629 0.286 2125547 Peakdale2_000211 C1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J14 compound treatment 1013380.0 -59600.0 -0.29 1039710.0 70600.0 0.42 1013960.0 -39280.9375 -0.224981271828104 -0.0555 -0.0995 2125548 Peakdale2_000212 C1CC1Nc2cc(nc(n2)c3ccccc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J15 compound treatment 955650.0 -117000.0 -0.57 787250.0 -182000.0 -1.08 812900.0 -240340.9375 -1.3765508980306 -1.75 -0.9501 2125549 Peakdale2_000213 C1CN(CCO1)c2cc(nc(n2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J16 compound treatment 293440.0 -779000.0 -3.81 401230.0 -568000.0 -3.38 487280.0 -565960.9375 -3.24153698021531 -6.02 -0.9976 2125550 Peakdale2_000214 CCN(CC)c1cc(nc(n1)c2ccncc2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J17 compound treatment 1094570.0 21600.0 0.11 937410.0 -31700.0 -0.19 938200.0 -115040.9375 -0.658896097656719 -0.4283 -0.6176 2125551 Peakdale2_000215 C1CC1Nc2cc(nc(n2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J18 compound treatment 1085700.0 12800.0 0.06 932900.0 -36200.0 -0.22 1008200.0 -45040.9375 -0.257971628174103 -0.2373 -0.6942 2125552 Peakdale2_000216 CN(C)CCNc1cc(nc(C)n1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J19 compound treatment 1186050.0 113000.0 0.55 976160.0 7040.0 0.04 1068920.0 15679.0625 0.0898017116399612 0.3951 0.7037 2125553 Peakdale2_000217 Cc1nc(NCCCO)cc(n1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J20 compound treatment 1308320.0 235000.0 1.15 996090.0 27000.0 0.16 1020320.0 -32920.9375 -0.188554420029398 0.6477 0.5506 2125554 Peakdale2_000218 Cc1nc(cc(n1)c2ccc(F)cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J21 compound treatment 1094680.0 21700.0 0.11 860380.0 -109000.0 -0.65 965490.0 -87750.9375 -0.50259282948271 -0.6022 -0.7291 2125555 Peakdale2_000219 CC(Nc1cc(nc(C)n1)c2cccnc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J22 compound treatment 1039080.0 -33900.0 -0.17 891440.0 -77700.0 -0.46 1103150.0 49909.0625 0.285853777216961 -0.1972 -0.3472 2125556 Peakdale2_000220 Cc1nc(cc(n1)c2ccc(F)cc2)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J23 mock treatment 1148040.0 75100.0 0.37 990510.0 21400.0 0.13 1061890.0 8649.0625 0.0495374399190642 0.3139 0.8017 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 J24 mock treatment 1235710.0 163000.0 0.8 1009330.0 40200.0 0.24 1063420.0 10179.0625 0.0583005033234699 0.6309 0.7578 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K01 compound treatment 546740.0 -526000.0 -2.57 536480.0 -433000.0 -2.57 537390.0 -515850.9375 -2.95453233498997 -4.6755 -0.9978 2125557 Peakdale2_000221 Cc1cnc(CNc2ncc(cn2)c3cc4ccccc4s3)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K02 compound treatment 994560.0 -78400.0 -0.38 950850.0 -18300.0 -0.11 988700.0 -64540.9375 -0.369657730387117 -0.4972 -0.9154 2125558 Peakdale2_000222 Cc1nc(NC2CCCCC2)cc(n1)c3cncc(Br)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K03 compound treatment 1043430.0 -29500.0 -0.14 956320.0 -12800.0 -0.08 1018890.0 -34350.9375 -0.196744734191686 -0.2408 -0.9423 2125559 Peakdale2_000223 CCN(CC)c1ncc(cn1)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K04 compound treatment 1002980.0 -70000.0 -0.34 895760.0 -73400.0 -0.44 980340.0 -72900.9375 -0.417539567028184 -0.6903 -0.9948 2125560 Peakdale2_000224 CCN(CC)c1ncc(cn1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K05 compound treatment 658720.0 -414000.0 -2.02 584640.0 -384000.0 -2.29 486730.0 -566510.9375 -3.24468710104696 -4.3618 -0.979 2125561 Peakdale2_000225 C1CN(CCO1)c2ncc(cn2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K06 compound treatment 823550.0 -249000.0 -1.22 690030.0 -279000.0 -1.66 672830.0 -380410.9375 -2.17880076146532 -2.9196 -0.9739 2125562 Peakdale2_000226 CN1CCN(CC1)c2ncc(cn2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K07 compound treatment 1088760.0 15800.0 0.08 847260.0 -122000.0 -0.72 938930.0 -114310.9375 -0.654715028189257 -0.7517 -0.7673 2125563 Peakdale2_000227 OCCCNc1ncc(cn1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K08 compound treatment 1147520.0 74600.0 0.36 989440.0 20300.0 0.12 1010560.0 -42680.9375 -0.244454746060117 0.139 0.3054 2125564 Peakdale2_000228 Fc1ccc(cc1)c2cnc(nc2)N3CCN(CC3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K09 compound treatment 1214100.0 141000.0 0.69 1004000.0 34900.0 0.21 992590.0 -60650.9375 -0.347377784868726 0.3174 0.3969 2125565 Peakdale2_000229 Cc1ccc(cc1)c2cnc(nc2)N3CCC(O)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K10 compound treatment 1053300.0 -19600.0 -0.1 991530.0 22400.0 0.13 951200.0 -102040.9375 -0.584438696181376 -0.3159 -0.5203 2125566 Peakdale2_000230 Fc1ccc(cc1)c2cnc(NCCc3c[nH]c4ccccc34)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K11 compound treatment 1226480.0 154000.0 0.75 956800.0 -12300.0 -0.07 1096280.0 43039.0625 0.246505904283452 0.5331 0.6723 2125567 Peakdale2_000231 COc1ccc(cc1)c2cnc(NCc3ccco3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K12 compound treatment 1187000.0 114000.0 0.56 808700.0 -160000.0 -0.95 827110.0 -226130.9375 -1.29516323072563 -0.9768 -0.5738 2125568 Peakdale2_000232 Cc1nc(NCc2ccncc2)cc(n1)c3cncc(c3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K13 compound treatment 1374690.0 302000.0 1.47 1167110.0 198000.0 1.18 1040000.0 -13240.9375 -0.0758373691805711 1.4872 0.7876 2125569 Peakdale2_000233 C(Cc1ccccc1)Nc2ncc(cn2)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K14 compound treatment 1199680.0 127000.0 0.62 833840.0 -135000.0 -0.8 867300.0 -185940.9375 -1.0649753103184 -0.7218 -0.4906 2125570 Peakdale2_000234 Cc1nc(cc(n1)c2cncc(c2)c3ccc(F)cc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K15 compound treatment 1185440.0 113000.0 0.55 945760.0 -23400.0 -0.14 1019010.0 -34230.9375 -0.196057435101144 0.124 0.2066 2125571 Peakdale2_000235 Cc1ccc(cc1)c2cnc(NC3CCCCC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K16 compound treatment 1117790.0 44900.0 0.22 767090.0 -202000.0 -1.2 1006010.0 -47230.9375 -0.270514836576487 -0.7233 -0.5782 2125572 Peakdale2_000236 Cc1nc(NCC=C)cc(n1)c2cncc(c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K17 compound treatment 1260190.0 187000.0 0.91 974750.0 5630.0 0.03 1011520.0 -41720.9375 -0.238956353335784 0.4096 0.4329 2122941 Peakdale2_000237 O=C(NCCN1CCOCC1)c2ccc3cc[nH]c3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K18 compound treatment 1140490.0 67600.0 0.33 994960.0 25800.0 0.15 1138770.0 85529.0625 0.4898670572594 0.5621 0.9209 2125573 Peakdale2_000238 Cc1ccc(cc1)c2cncc(c2)c3cc(NCc4ccccc4)nc(C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K19 compound treatment 1096960.0 24000.0 0.12 967650.0 -1470.0 -0.01 1073630.0 20389.0625 0.11677820094372 0.1301 0.7848 2125574 Peakdale2_000239 CC(=O)Nc1ccccc1c2cnn(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K20 compound treatment 1252090.0 179000.0 0.88 1042000.0 72900.0 0.43 1100290.0 47049.0625 0.269473148892385 0.9112 0.8993 2125575 Peakdale2_000240 CC(Nc1cc(nc(C)n1)c2cncc(c2)c3ccc(C)cc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K21 compound treatment 1172640.0 99700.0 0.49 941640.0 -27500.0 -0.16 1015650.0 -37590.9375 -0.21530180963631 0.0626 0.1123 2125576 Peakdale2_000241 Cn1cc(cn1)c2ccccc2NC(=O)Nc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K22 compound treatment 1109250.0 36300.0 0.18 851560.0 -118000.0 -0.7 930270.0 -122970.9375 -0.704315112556678 -0.7078 -0.7021 2125577 Peakdale2_000242 Cc1ccc(cc1)c2cncc(c2)c3cc(NC4CC4)nc(C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K23 mock treatment 1160640.0 87700.0 0.43 1023640.0 54500.0 0.32 1097280.0 44039.0625 0.252233396704633 0.5802 0.9774 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 K24 mock treatment 1111720.0 38800.0 0.19 951380.0 -17700.0 -0.11 1062730.0 9489.0625 0.0543485335528556 0.0799 0.3572 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L01 compound treatment 1179840.0 107000.0 0.52 1050910.0 81800.0 0.49 896550.0 -156690.9375 -0.897446156998875 0.0642 0.056 2125578 Peakdale2_000243 OCCn1cc(cn1)c2ccnc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L02 compound treatment 972260.0 -101000.0 -0.49 946410.0 -22700.0 -0.14 857980.0 -195260.9375 -1.1183555396838 -1.0076 -0.8198 2125579 Peakdale2_000244 OC1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L03 compound treatment 1041150.0 -31800.0 -0.16 838130.0 -131000.0 -0.78 936230.0 -117010.9375 -0.670179257726444 -0.9263 -0.8913 2125580 Peakdale2_000245 Clc1ccc(cc1)c2cnn(Cc3ccccc3)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L04 compound treatment 961440.0 -111000.0 -0.54 874110.0 -95000.0 -0.57 891720.0 -161520.9375 -0.925109945393176 -1.1748 -0.9684 2125581 Peakdale2_000246 CN(Cc1ccccc1)c2cc(nc(n2)c3cccnc3)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L05 compound treatment 1110950.0 38000.0 0.19 973760.0 4640.0 0.03 1014400.0 -38840.9375 -0.222461175162785 -0.0053 -0.0181 2125582 Peakdale2_000247 Cn1cc(cn1)c2ccc(cn2)C(=O)NCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L06 compound treatment 933060.0 -140000.0 -0.68 897520.0 -71600.0 -0.43 899300.0 -153940.9375 -0.88169555284063 -1.1494 -0.9627 2125583 Peakdale2_000248 C=CCNc1cc(nc(n1)c2ccncc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L07 compound treatment 1196510.0 124000.0 0.6 1022270.0 53100.0 0.32 1098970.0 45729.0625 0.261912858896427 0.6823 0.9345 2125584 Peakdale2_000249 CN(Cc1ccccc1)C(=O)c2ccc(nc2)c3cnn(c3)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L08 compound treatment 1223850.0 151000.0 0.74 921230.0 -47900.0 -0.28 1015040.0 -38200.9375 -0.21879558001323 0.135 0.1645 2125585 Peakdale2_000250 Cc1nc(cc(n1)c2ccncc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L09 compound treatment 1175040.0 102000.0 0.5 939480.0 -29600.0 -0.18 1046720.0 -6520.9375 -0.03734862011024 0.1647 0.3105 2125586 Peakdale2_000251 Fc1ccc(c(F)c1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L10 compound treatment 1133600.0 60700.0 0.3 964000.0 -5120.0 -0.03 981520.0 -71720.9375 -0.410781125971191 -0.0836 -0.1648 2125587 Peakdale2_000252 Cc1nc(NCCc2ccccc2)cc(n1)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L11 compound treatment 1102330.0 29400.0 0.14 853400.0 -116000.0 -0.69 983040.0 -70200.9375 -0.402075337490997 -0.5465 -0.6748 2125588 Peakdale2_000253 CN(Cc1ccccc1)C(=O)c2ccc(nc2)c3cnn(c3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L12 compound treatment 814960.0 -258000.0 -1.26 966020.0 -3100.0 -0.02 934360.0 -118880.9375 -0.680889668554051 -1.1315 -0.7898 2125589 Peakdale2_000254 C1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L13 compound treatment 1414730.0 342000.0 1.67 973460.0 4340.0 0.03 1095730.0 42489.0625 0.243355783451803 1.1195 0.6633 2125590 Peakdale2_000255 CN(Cc1ccccc1)c2cc(nc(n2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L14 compound treatment 974090.0 -98800.0 -0.48 901120.0 -68000.0 -0.4 862400.0 -190840.9375 -1.09304002318218 -1.1434 -0.9063 2125591 Peakdale2_000256 CCN(CC)c1cc(nc(n1)c2cccnc2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L15 compound treatment 1053680.0 -19300.0 -0.09 1069710.0 101000.0 0.6 1063870.0 10629.0625 0.060877874913001 0.3262 0.536 2125592 Peakdale2_000257 C1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L16 compound treatment 1020450.0 -52500.0 -0.26 855930.0 -113000.0 -0.67 1006980.0 -46260.9375 -0.264959168927942 -0.6896 -0.8986 2125593 Peakdale2_000258 C1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L17 compound treatment 1181760.0 109000.0 0.53 984210.0 15100.0 0.09 1105140.0 51899.0625 0.297251487135109 0.5304 0.8614 2125594 Peakdale2_000259 CN(C)CCNc1cc(nc(C)n1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L18 compound treatment 1422910.0 350000.0 1.71 1036340.0 67200.0 0.4 1047800.0 -5440.9375 -0.0311629282953653 1.2 0.6833 2125595 Peakdale2_000260 Cc1nc(NCCC#N)cc(n1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L19 compound treatment 1340270.0 267000.0 1.31 945820.0 -23300.0 -0.14 1061490.0 8249.0625 0.0472464429505921 0.7014 0.5336 2125596 Peakdale2_000261 Cc1nc(NCC=C)cc(n1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L20 compound treatment 1145620.0 72700.0 0.36 883290.0 -85800.0 -0.51 878910.0 -174330.9375 -0.998479123308495 -0.6661 -0.5663 2125597 Peakdale2_000262 CN(Cc1ccccc1)c2cc(nc(C)n2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L21 compound treatment 1091970.0 19000.0 0.09 938970.0 -30200.0 -0.18 1033950.0 -19290.9375 -0.110488698328712 -0.1136 -0.4935 2125598 Peakdale2_000263 Cc1nc(NC2CCCCC2)cc(n1)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L22 compound treatment 1025840.0 -47100.0 -0.23 997700.0 28600.0 0.17 975430.0 -77810.9375 -0.445661554816179 -0.292 -0.5515 2125599 Peakdale2_000264 Cc1nc(NCCc2ccccc2)cc(n1)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L23 mock treatment 1194470.0 122000.0 0.59 953920.0 -15200.0 -0.09 1030730.0 -22510.9375 -0.128931223924912 0.2162 0.3519 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 L24 mock treatment 1082720.0 9790.0 0.05 954340.0 -14800.0 -0.09 1142290.0 89049.0625 0.510027830581955 0.2713 0.522 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M01 compound treatment 1159420.0 86500.0 0.42 961600.0 -7520.0 -0.04 987360.0 -65880.9375 -0.377332570231499 3.0E-4 5.0E-4 2125600 Peakdale2_000265 COCCNc1ncc(cn1)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M02 compound treatment 890370.0 -183000.0 -0.89 709050.0 -260000.0 -1.55 824890.0 -228350.9375 -1.30787826390065 -2.163 -0.9773 2125601 Peakdale2_000266 Cc1nc(NCCc2c[nH]c3ccccc23)cc(n1)c4cncc(Br)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M03 compound treatment 1224680.0 152000.0 0.74 960080.0 -9040.0 -0.05 925280.0 -127960.9375 -0.732895299738367 -0.0261 -0.025 2125602 Peakdale2_000267 CCN(CC)c1ncc(cn1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M04 compound treatment 1109990.0 37100.0 0.18 854650.0 -114000.0 -0.68 927960.0 -125280.9375 -0.717545620049604 -0.7028 -0.6989 2125603 Peakdale2_000268 Fc1ccc(cc1)c2cnc(NCc3ccncc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M05 compound treatment 1181950.0 109000.0 0.53 920130.0 -49000.0 -0.29 1005730.0 -47510.9375 -0.272118534454418 -0.0178 -0.0268 2125604 Peakdale2_000269 C1CN(CCO1)c2ncc(cn2)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M06 compound treatment 1283520.0 211000.0 1.03 1054720.0 85600.0 0.51 1027150.0 -26090.9375 -0.149435646792737 0.8016 0.6925 2125605 Peakdale2_000270 Fc1ccc(cc1)c2cnc(NCc3ccccc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M07 compound treatment 1092680.0 19700.0 0.1 879520.0 -89600.0 -0.53 945840.0 -107400.9375 -0.615138055558902 -0.6071 -0.7408 2125606 Peakdale2_000271 OCCCNc1ncc(cn1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M08 compound treatment 1187410.0 114000.0 0.56 919310.0 -49800.0 -0.3 1049440.0 -3800.9375 -0.0217698407246297 0.1393 0.22 2125607 Peakdale2_000272 C1CN(CCN1c2ccccn2)c3ncc(cn3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M09 compound treatment 1238130.0 165000.0 0.81 1005880.0 36800.0 0.22 1035210.0 -18030.9375 -0.103272057878024 0.5326 0.6321 2125608 Peakdale2_000273 COc1ccc(cc1)c2cnc(nc2)N3CCC(O)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M10 compound treatment 1151970.0 79000.0 0.39 866880.0 -102000.0 -0.61 836200.0 -217040.9375 -1.2431003246171 -0.8458 -0.5887 2125609 Peakdale2_000274 CCN(CC)c1cc(nc(C)n1)c2cncc(c2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M11 compound treatment 1356930.0 284000.0 1.39 1182000.0 213000.0 1.27 980740.0 -72500.9375 -0.415248570059712 1.2922 0.6718 2125610 Peakdale2_000275 Clc1ccc(cc1)c2cnc(NCc3ccco3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M12 compound treatment 1270810.0 198000.0 0.97 895070.0 -74100.0 -0.44 1005440.0 -47800.9375 -0.27377950725656 0.1459 0.133 2125611 Peakdale2_000276 Cc1ccc(cc1)c2cncc(c2)c3cc(nc(C)n3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M13 compound treatment 1346400.0 273000.0 1.34 1016910.0 47800.0 0.28 1012800.0 -40440.9375 -0.231625163036673 0.8017 0.5787 2125612 Peakdale2_000277 Cc1ccc(cc1)c2cnc(nc2)N3CCN(CC3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M14 compound treatment 1142830.0 69900.0 0.34 1040210.0 71100.0 0.42 1116590.0 63349.0625 0.362831275357623 0.6507 0.9958 2125613 Peakdale2_000278 CN(Cc1ccccc1)c2cc(nc(C)n2)c3cncc(c3)c4ccc(C)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M15 compound treatment 983390.0 -89500.0 -0.44 936580.0 -32500.0 -0.19 985450.0 -67790.9375 -0.388272080755953 -0.5885 -0.9551 2125614 Peakdale2_000279 Clc1ccc(cc1)c2cnc(NC3CCCCC3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M16 compound treatment 760320.0 -313000.0 -1.53 751250.0 -218000.0 -1.3 709570.0 -343670.9375 -1.96837268991116 -2.7663 -0.9851 2125615 Peakdale2_000280 CN1CCN(CC1)c2cc(nc(C)n2)c3cncc(c3)c4ccc(C)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M17 compound treatment 1230320.0 157000.0 0.77 1079530.0 110000.0 0.66 1044570.0 -8670.9375 -0.0496627288157775 0.7943 0.7847 2125616 Peakdale2_000281 Clc1ccc(cc1)c2cnc(NCCc3c[nH]c4ccccc34)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M18 compound treatment 907160.0 -166000.0 -0.81 722720.0 -246000.0 -1.47 834820.0 -218420.9375 -1.25100426415833 -2.0359 -0.9741 2125617 Peakdale2_000282 Cc1nc(NCc2ccccc2)cc(n1)c3cncc(c3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M19 compound treatment 1233860.0 161000.0 0.79 1036800.0 67700.0 0.4 992410.0 -60830.9375 -0.348408733504538 0.4851 0.5109 2125618 Peakdale2_000283 Cn1cc(cn1)c2ccccc2NC(=O)/C=C/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M20 compound treatment 970790.0 -102000.0 -0.5 777240.0 -192000.0 -1.14 893620.0 -159620.9375 -0.914227709792934 -1.4747 -0.9546 2125619 Peakdale2_000284 CC(Nc1cc(nc(C)n1)c2cncc(c2)c3cccs3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M21 compound treatment 1309530.0 237000.0 1.16 889440.0 -79700.0 -0.47 942560.0 -110680.9375 -0.633924230700373 0.0278 0.0199 2125620 Peakdale2_000285 Cn1cc(cn1)c2ccccc2NC(=O)Nc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M22 compound treatment 1039230.0 -33700.0 -0.16 756720.0 -212000.0 -1.26 886270.0 -166970.9375 -0.956324779088608 -1.3764 -0.8642 2125621 Peakdale2_000286 COc1ccc(cc1)c2cncc(c2)c3cc(NC4CC4)nc(C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M23 mock treatment 1095770.0 22800.0 0.11 1058470.0 89300.0 0.53 964640.0 -88600.9375 -0.507461198040713 0.0782 0.1052 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 M24 mock treatment 1079720.0 6790.0 0.03 907550.0 -61600.0 -0.37 1052480.0 -760.9375 -0.00435826376424183 -0.1948 -0.5297 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N01 compound treatment 1226040.0 153000.0 0.75 1009530.0 40400.0 0.24 1001040.0 -52200.9375 -0.298980473909753 0.398 0.4734 2125622 Peakdale2_000287 Cn1cc(cn1)c2cnccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N02 compound treatment 915770.0 -157000.0 -0.77 746970.0 -222000.0 -1.32 823720.0 -229520.9375 -1.31457943003343 -1.965 -0.9749 2125623 Peakdale2_000288 C(Nc1cc(nc(n1)c2ccccc2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N03 compound treatment 1298920.0 226000.0 1.1 940910.0 -28200.0 -0.17 982500.0 -70740.9375 -0.405168183398434 0.3067 0.2581 2125624 Peakdale2_000289 Cn1cc(cn1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N04 compound treatment 1208170.0 135000.0 0.66 950320.0 -18800.0 -0.11 968400.0 -84840.9375 -0.485925826537076 0.0364 0.0439 2125625 Peakdale2_000290 C=CCNc1cc(nc(n1)c2cccnc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N05 compound treatment 1347910.0 275000.0 1.34 1041810.0 72700.0 0.43 1122950.0 69709.0625 0.399258127156329 1.2557 0.8562 2125626 Peakdale2_000291 Cn1cc(cn1)c2ccc(cn2)C(=O)NCc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N06 compound treatment 802250.0 -271000.0 -1.32 657690.0 -311000.0 -1.85 725560.0 -327680.9375 -1.87679008609648 -2.9163 -0.9887 2125627 Peakdale2_000292 C(Nc1cc(nc(n1)c2ccncc2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N07 compound treatment 1309880.0 237000.0 1.16 988720.0 19600.0 0.12 1013710.0 -39530.9375 -0.226413144933399 0.6049 0.5103 2125628 Peakdale2_000293 Clc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N08 compound treatment 1130770.0 57800.0 0.28 876040.0 -93100.0 -0.55 905660.0 -147580.9375 -0.845268701041924 -0.6444 -0.6143 2125629 Peakdale2_000294 Cc1nc(cc(n1)c2ccncc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N09 compound treatment 1380490.0 308000.0 1.5 988040.0 18900.0 0.11 917440.0 -135800.9375 -0.77779884032042 0.4834 0.2851 2125630 Peakdale2_000295 Fc1ccc(c(F)c1)n2cc(cn2)c3ccc(cn3)C(=O)NCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N10 compound treatment 1157570.0 84600.0 0.41 885650.0 -83500.0 -0.5 945220.0 -108020.9375 -0.618689100860034 -0.405 -0.4528 2125631 Peakdale2_000296 CC(Nc1cc(nc(C)n1)c2ccncc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N11 compound treatment 1274520.0 202000.0 0.98 1033320.0 64200.0 0.38 1042350.0 -10890.9375 -0.0623777619907976 0.753 0.7116 2124205 Peakdale2_000297 CCN1Cc2ccccc2-n3cccc3C1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N12 compound treatment 1020350.0 -52600.0 -0.26 895000.0 -74100.0 -0.44 1025600.0 -27640.9375 -0.158313260045566 -0.4942 -0.9252 2125632 Peakdale2_000298 CN(Cc1ccccc1)c2cc(nc(n2)c3ccccc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N13 compound treatment 1414530.0 342000.0 1.67 1098010.0 129000.0 0.77 1086650.0 33409.0625 0.191350152267487 1.5166 0.8213 2125633 Peakdale2_000299 C=CCNc1cc(nc(n1)c2cccnc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N14 compound treatment 1067170.0 -5760.0 -0.03 953720.0 -15400.0 -0.09 876730.0 -176510.9375 -1.01096505678667 -0.6528 -0.6429 2125634 Peakdale2_000300 C1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N15 compound treatment 1168000.0 95100.0 0.46 1010360.0 41200.0 0.25 987140.0 -66100.9375 -0.378592618564158 0.1912 0.2952 2125635 Peakdale2_000301 CN(Cc1ccccc1)c2cc(nc(n2)c3ccncc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N16 compound treatment 471960.0 -601000.0 -2.94 622650.0 -346000.0 -2.06 663360.0 -389880.9375 -2.23304011469389 -4.174 -0.9879 2125636 Peakdale2_000302 CN(Cc1ccccc1)c2cc(nc(n2)c3ccncc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N17 compound treatment 1272200.0 199000.0 0.97 1055800.0 86700.0 0.52 1080480.0 27239.0625 0.156011524028805 0.9498 0.8536 2125637 Peakdale2_000303 COCCNc1cc(nc(C)n1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N18 compound treatment 1246560.0 174000.0 0.85 997540.0 28400.0 0.17 1036190.0 -17050.9375 -0.0976591153052678 0.5309 0.61 2125638 Peakdale2_000304 Cc1cnc(CNc2cc(nc(C)n2)c3ccc(F)cc3)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N19 compound treatment 1293290.0 220000.0 1.08 1082080.0 113000.0 0.67 1087870.0 34629.0625 0.198337693021327 1.1239 0.8751 2125639 Peakdale2_000305 CN1CCN(CC1)c2cc(nc(C)n2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N20 compound treatment 1174770.0 102000.0 0.5 992390.0 23300.0 0.14 1069480.0 16239.0625 0.0930091073958221 0.4208 0.802 2125640 Peakdale2_000306 Cc1nc(NCCCO)cc(n1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N21 compound treatment 1107200.0 34300.0 0.17 942130.0 -27000.0 -0.16 1013960.0 -39280.9375 -0.224981271828104 -0.1259 -0.3897 2125641 Peakdale2_000307 Cc1nc(NC2CC2)cc(n1)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N22 compound treatment 1046660.0 -26300.0 -0.13 976660.0 7540.0 0.04 967160.0 -86080.9375 -0.493027917139339 -0.3329 -0.6509 2125642 Peakdale2_000308 Cc1nc(cc(n1)c2ccc(F)cc2)N3CCN(CC3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N23 mock treatment 1297050.0 224000.0 1.09 1096550.0 127000.0 0.76 1021890.0 -31350.9375 -0.179562256928145 0.966 0.7189 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 N24 mock treatment 1130050.0 57100.0 0.28 901440.0 -67700.0 -0.4 1067320.0 14079.0625 0.0806377237660728 -0.0247 -0.0498 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O01 compound treatment 1022110.0 -50800.0 -0.25 871680.0 -97400.0 -0.58 875520.0 -177720.9375 -1.0178953226163 -1.0656 -0.89 2125643 Peakdale2_000309 COCCNc1ncc(cn1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O02 compound treatment 1191760.0 119000.0 0.58 1201720.0 233000.0 1.38 1101760.0 48519.0625 0.27789256275152 1.2942 0.8483 2123203 Peakdale2_000310 CN1CCN(CC1)C2c3cccn3-c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O03 compound treatment 1111860.0 38900.0 0.19 923580.0 -45500.0 -0.27 1066080.0 12839.0625 0.0735356331638093 -0.0041 -0.0121 2125644 Peakdale2_000311 Cc1ccc(cc1)c2cnc(NCc3ccncc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O04 compound treatment 1216920.0 144000.0 0.7 992020.0 22900.0 0.14 965690.0 -87550.9375 -0.501447330998474 0.1953 0.2233 2125645 Peakdale2_000312 C(Nc1ncc(cn1)c2ccccc2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O05 compound treatment 1022610.0 -50300.0 -0.25 918130.0 -51000.0 -0.3 948120.0 -105120.9375 -0.602079372838611 -0.6646 -0.9262 2125646 Peakdale2_000313 Cc1ccc(cc1)c2cnc(nc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O06 compound treatment 1166140.0 93200.0 0.46 955800.0 -13300.0 -0.08 1003610.0 -49630.9375 -0.28426081838732 0.0531 0.0978 2125647 Peakdale2_000314 C(Nc1ncc(cn1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O07 compound treatment 1104270.0 31300.0 0.15 817670.0 -151000.0 -0.9 913050.0 -140190.9375 -0.802942532049402 -0.8952 -0.736 2125648 Peakdale2_000315 OCCCNc1ncc(cn1)c2cc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O08 compound treatment 1283200.0 210000.0 1.03 989280.0 20200.0 0.12 1043010.0 -10230.9375 -0.0585976169928186 0.6285 0.6067 2125649 Peakdale2_000316 Fc1ccc(cc1)c2cnc(NCc3ccc(Cl)cc3)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O09 compound treatment 1326190.0 253000.0 1.24 1088110.0 119000.0 0.71 1029620.0 -23620.9375 -0.135288740512422 1.0448 0.7297 2125650 Peakdale2_000317 OC1CCN(CC1)c2ncc(cn2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O10 compound treatment 1272340.0 199000.0 0.97 979220.0 10100.0 0.06 1104750.0 51509.0625 0.295017765090849 0.7675 0.7526 2125651 Peakdale2_000318 CCN(CC)c1cc(nc(C)n1)c2cncc(c2)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O11 compound treatment 1439320.0 366000.0 1.79 932930.0 -36200.0 -0.22 1035310.0 -17930.9375 -0.102699308635906 0.85 0.4707 2125652 Peakdale2_000319 C(Nc1ncc(cn1)c2cccs2)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O12 compound treatment 1032320.0 -40600.0 -0.2 850490.0 -119000.0 -0.71 890240.0 -163000.9375 -0.933586634176523 -1.0609 -0.8938 2125653 Peakdale2_000320 Cc1nc(cc(n1)c2cncc(c2)c3cccs3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O13 compound treatment 1230400.0 157000.0 0.77 1058400.0 89300.0 0.53 1034090.0 -19150.9375 -0.109686849389746 0.6874 0.7303 2125654 Peakdale2_000321 CC(Nc1ncc(cn1)c2ccc(C)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O14 compound treatment 1183040.0 110000.0 0.54 951950.0 -17200.0 -0.1 912850.0 -140390.9375 -0.804088030533638 -0.2126 -0.2185 2125655 Peakdale2_000322 CN(Cc1ccccc1)c2cc(nc(C)n2)c3cncc(c3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O15 compound treatment 1013570.0 -59400.0 -0.29 1048960.0 79800.0 0.47 1026310.0 -26930.9375 -0.154246740426529 0.0176 0.0305 2125656 Peakdale2_000323 C1CCC(CC1)Nc2ncc(cn2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O16 compound treatment 767600.0 -305000.0 -1.49 712840.0 -256000.0 -1.52 888400.0 -164840.9375 -0.944125220231494 -2.2863 -0.9803 2125657 Peakdale2_000324 CN1CCN(CC1)c2cc(nc(C)n2)c3cncc(c3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O17 compound treatment 1256870.0 184000.0 0.9 1014400.0 45300.0 0.27 1144570.0 91329.0625 0.523086513302246 0.9763 0.9089 2125658 Peakdale2_000325 CCNC(=O)Nc1ccccc1c2cnn(c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O18 compound treatment 1115200.0 42300.0 0.21 895520.0 -73600.0 -0.44 1023080.0 -30160.9375 -0.172746540946941 -0.2332 -0.4538 2125659 Peakdale2_000326 Cc1nc(NCc2ccccc2)cc(n1)c3cncc(c3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O19 compound treatment 1306640.0 234000.0 1.14 1118110.0 149000.0 0.89 1058560.0 5319.0625 0.030464890156534 1.1883 0.8221 2125660 Peakdale2_000327 Cn1cc(cn1)c2ccccc2NC(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O20 compound treatment 1104000.0 31100.0 0.15 831630.0 -137000.0 -0.82 931270.0 -121970.9375 -0.698587620135498 -0.7877 -0.7253 2125661 Peakdale2_000328 CC(Nc1cc(nc(C)n1)c2cncc(c2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O21 compound treatment 1203090.0 130000.0 0.64 986900.0 17800.0 0.11 1113860.0 60619.0625 0.347195221047801 0.6286 0.8586 2125662 Peakdale2_000329 Cc1cc(C)cc(NC(=O)Nc2ccccc2c3cnn(C)c3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O22 compound treatment 633640.0 -439000.0 -2.15 505810.0 -463000.0 -2.76 565810.0 -487430.9375 -2.79175700038003 -4.4417 -0.9934 2125663 Peakdale2_000330 Cc1nc(NC2CC2)cc(n1)c3cncc(c3)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O23 mock treatment 1316260.0 243000.0 1.19 1162560.0 193000.0 1.15 1142140.0 88899.0625 0.509168706718778 1.6445 0.9501 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 O24 mock treatment 981920.0 -91000.0 -0.44 905960.0 -63200.0 -0.38 1014920.0 -38320.9375 -0.219482879103771 -0.6003 -0.965 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P01 compound treatment 1043040.0 -29900.0 -0.15 934730.0 -34400.0 -0.2 849320.0 -203920.9375 -1.16795562405122 -0.8767 -0.7339 2125664 Peakdale2_000331 COc1ccc(cc1)c2cnn(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P02 compound treatment 993600.0 -79300.0 -0.39 896000.0 -73100.0 -0.43 997120.0 -56120.9375 -0.321432244200779 -0.6604 -0.9926 2125665 Peakdale2_000332 C(Nc1cc(nc(n1)c2ccccc2)c3cccnc3)c4ccco4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P03 compound treatment 1058460.0 -14500.0 -0.07 1034170.0 65000.0 0.39 963650.0 -89590.9375 -0.513131415537682 -0.1138 -0.176 2125666 Peakdale2_000333 OCCn1cc(cn1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P04 compound treatment 1062820.0 -10100.0 -0.05 831920.0 -137000.0 -0.82 1010240.0 -43000.9375 -0.246287543634895 -0.6418 -0.7518 2125667 Peakdale2_000334 C(Nc1cc(nc(n1)c2cccnc2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P05 compound treatment 1376290.0 303000.0 1.48 1100570.0 131000.0 0.78 1142560.0 89319.0625 0.511574253535674 1.6024 0.9146 2125668 Peakdale2_000335 Cn1cc(cn1)c2ccc(cn2)C(=O)NC3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P06 compound treatment 897450.0 -175000.0 -0.86 753880.0 -215000.0 -1.28 906790.0 -146450.9375 -0.83879663460599 -1.7183 -0.9796 2125669 Peakdale2_000336 CC(Nc1cc(nc(n1)c2ccncc2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P07 compound treatment 1326080.0 253000.0 1.24 971290.0 2170.0 0.01 993560.0 -59680.9375 -0.341822117220181 0.5242 0.4085 2125670 Peakdale2_000337 Clc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)NCc4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P08 compound treatment 1211520.0 139000.0 0.68 934500.0 -34600.0 -0.21 1147110.0 93869.0625 0.537634344052044 0.5825 0.6554 2125671 Peakdale2_000338 Cc1nc(NCCCO)cc(n1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P09 compound treatment 1281530.0 209000.0 1.02 1077140.0 108000.0 0.64 1075460.0 22219.0625 0.12725951207448 1.0327 0.8525 2125672 Peakdale2_000339 CN(Cc1ccccc1)C(=O)c2ccc(nc2)c3cnn(c3)c4ccc(C)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P10 compound treatment 1185600.0 113000.0 0.55 810320.0 -159000.0 -0.94 952500.0 -100740.9375 -0.576992956033841 -0.5605 -0.4535 2125673 Peakdale2_000340 Cc1nc(NCc2ccc(Cl)cc2)cc(n1)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P11 compound treatment 998080.0 -74900.0 -0.37 837130.0 -132000.0 -0.78 971170.0 -82070.9375 -0.470060672530407 -0.9357 -0.9497 2125674 Peakdale2_000341 Brc1ccc(cc1)n2cc(cn2)c3ccc(cn3)C(=O)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P12 compound treatment 703620.0 -369000.0 -1.8 774040.0 -195000.0 -1.16 877330.0 -175910.9375 -1.00752856133396 -2.2932 -0.9676 2125675 Peakdale2_000342 C=CCNc1cc(nc(n1)c2ccccc2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P13 compound treatment 935940.0 -137000.0 -0.67 868960.0 -100000.0 -0.6 836170.0 -217070.9375 -1.24327214938974 -1.4481 -0.945 2125676 Peakdale2_000343 CN1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P14 compound treatment 1121290.0 48400.0 0.24 879860.0 -89300.0 -0.53 921090.0 -132150.9375 -0.756893492983113 -0.6071 -0.6362 2125677 Peakdale2_000344 CN(Cc1ccccc1)c2cc(nc(n2)c3cccnc3)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P15 compound treatment 1016380.0 -56600.0 -0.28 932030.0 -37100.0 -0.22 1006010.0 -47230.9375 -0.270514836576487 -0.4431 -0.9953 2125678 Peakdale2_000345 C=CCNc1cc(nc(n1)c2ccncc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P16 compound treatment 457070.0 -616000.0 -3.01 338670.0 -630000.0 -3.75 435620.0 -617620.9375 -3.53741923869348 -5.9441 -0.9959 2125679 Peakdale2_000346 C=CCNc1cc(nc(n1)c2ccncc2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P17 compound treatment 1291540.0 219000.0 1.07 972280.0 3160.0 0.02 1053150.0 -90.9375 -5.20843842051077E-4 0.6272 0.5871 2125680 Peakdale2_000347 CCN(CC)c1cc(nc(C)n1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P18 compound treatment 1231610.0 159000.0 0.78 1009540.0 40400.0 0.24 1204670.0 151429.0625 0.867308807815178 1.0871 0.9152 2125681 Peakdale2_000348 COCCNc1cc(nc(C)n1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P19 compound treatment 1301450.0 229000.0 1.12 1130080.0 161000.0 0.96 1019840.0 -33400.9375 -0.191303616391565 1.0868 0.7328 2125682 Peakdale2_000349 Cc1nc(cc(n1)c2cccnc2)N3CCC(O)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P20 compound treatment 1136370.0 63400.0 0.31 937140.0 -32000.0 -0.19 962880.0 -90360.9375 -0.517541584701991 -0.2297 -0.3631 2125683 Peakdale2_000350 Cc1nc(NCC=C)cc(n1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P21 compound treatment 888640.0 -184000.0 -0.9 845190.0 -124000.0 -0.74 885170.0 -168070.9375 -0.962625020751906 -1.5011 -0.994 2125684 Peakdale2_000351 CCN(CC)c1cc(nc(n1)c2ccccc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P22 compound treatment 731800.0 -341000.0 -1.67 524720.0 -444000.0 -2.64 688270.0 -364970.9375 -2.09036827848229 -3.6949 -0.9829 2125685 Peakdale2_000352 CC(Nc1cc(nc(C)n1)c2ccc(F)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P23 mock treatment 1152560.0 79600.0 0.39 1053800.0 84700.0 0.5 1034130.0 -19110.9375 -0.109457749692899 0.4521 0.7003 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1305 P24 mock treatment 885870.0 -187000.0 -0.91 897330.0 -71800.0 -0.43 1000100.0 -53140.9375 -0.304364316785662 -0.9499 -0.9015 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A01 compound treatment 636420.0 -503000.0 -2.46 616540.0 -464000.0 -2.76 589120.0 -389721.509433962 -2.23212699165394 -4.301 -0.9962 2075074 MixCom4_000001 COc1ccc(CN2CCCN(Cc3ccc(OC)cc3)C2c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A02 compound treatment 632320.0 -507000.0 -2.48 718420.0 -362000.0 -2.15 665150.0 -313691.509433962 -1.79666574287161 -3.7114 -0.9917 2079852 MixCom4_000002 Cc1nc(NC2CCCCC2)cc(n1)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A03 compound treatment 832320.0 -307000.0 -1.5 781660.0 -299000.0 -1.78 824480.0 -154361.509433962 -0.884104375404959 -2.4032 -0.9656 2075075 MixCom4_000003 CN1CCN(CC1)c2ccc(CNC(=O)C3=Cc4ccccc4OC3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A04 compound treatment 745670.0 -394000.0 -1.92 790030.0 -291000.0 -1.73 811010.0 -167831.509433962 -0.961253698318256 -2.6634 -0.9654 2079853 MixCom4_000004 Fc1ccc(cc1)c2cc(NCc3ccccc3)nc(n2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A05 compound treatment 827550.0 -312000.0 -1.52 938820.0 -142000.0 -0.84 844480.0 -134361.509433962 -0.769554526981354 -1.811 -0.9513 2075076 MixCom4_000005 OC(CN1CCN(CC1)c2c(Cl)cncc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A06 compound treatment 369440.0 -770000.0 -3.76 565380.0 -515000.0 -3.06 690100.0 -288741.509433962 -1.65376480696316 -4.8958 -0.9551 2079854 MixCom4_000006 Fc1ccc(cc1)c2cc(NCc3ccccc3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A07 compound treatment 935540.0 -204000.0 -1.0 871270.0 -210000.0 -1.25 845530.0 -133311.509433962 -0.763540659939115 -1.7348 -0.9812 2075077 MixCom4_000007 CCc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)N3CCN(C)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A08 compound treatment 393510.0 -746000.0 -3.64 389980.0 -691000.0 -4.11 569340.0 -409501.509433962 -2.34541679174488 -5.8294 -0.9763 2079855 MixCom4_000008 Fc1ccc(cc1)c2cc(NCC=C)nc(n2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A09 compound treatment 954760.0 -184000.0 -0.9 901340.0 -179000.0 -1.07 900770.0 -78071.5094339621 -0.447153978593119 -1.3947 -0.9509 2075078 MixCom4_000009 CC(C)S(=O)(=O)NCc1ccc(cc1)N2CCN(C)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A10 compound treatment 944720.0 -195000.0 -0.95 856660.0 -224000.0 -1.33 965770.0 -13071.5094339621 -0.0748669712164036 -1.3614 -0.8308 2079856 MixCom4_000010 Cc1cnc(CNc2cc(nc(C)n2)c3ccccc3F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A11 compound treatment 972200.0 -167000.0 -0.82 893780.0 -187000.0 -1.11 949970.0 -28871.5094339621 -0.165361351471051 -1.2087 -0.87 2075079 MixCom4_000011 OC(CNCc1csc(n1)c2cccs2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A12 compound treatment 943840.0 -195000.0 -0.95 841630.0 -239000.0 -1.42 924650.0 -54191.5094339621 -0.310381459575335 -1.5515 -0.8913 2079857 MixCom4_000012 Cc1nc(NCCCO)cc(n1)c2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A13 compound treatment 978720.0 -161000.0 -0.78 917180.0 -164000.0 -0.97 916290.0 -62551.5094339621 -0.358263296216401 -1.2214 -0.9395 2075080 MixCom4_000013 O=C(CN1C(=O)c2ccccc2C1=O)N3CCC(=CC3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A14 compound treatment 870520.0 -269000.0 -1.31 869970.0 -211000.0 -1.25 868710.0 -110131.509433962 -0.630777385616157 -1.846 -0.9606 2079858 MixCom4_000014 Cc1nc(cc(n1)c2ccccc2F)N3CCN(CC3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A15 compound treatment 913540.0 -226000.0 -1.1 875460.0 -205000.0 -1.22 893920.0 -84921.5094339621 -0.486387301678203 -1.6224 -0.9457 2075081 MixCom4_000015 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A16 compound treatment 869890.0 -269000.0 -1.32 859320.0 -221000.0 -1.32 875200.0 -103641.509433962 -0.593605959802697 -1.8629 -0.9533 2079859 MixCom4_000016 Fc1ccccc1c2cc(nc(n2)c3ccccc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A17 compound treatment 687090.0 -452000.0 -2.21 713600.0 -367000.0 -2.18 778300.0 -200541.509433962 -1.14859997541506 -3.1993 -0.966 2075082 MixCom4_000017 Cc1cc(c(C)s1)S(=O)(=O)Nc2ccc3N4CCCC4COc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A18 compound treatment 588690.0 -551000.0 -2.69 546640.0 -534000.0 -3.18 620420.0 -358421.509433962 -2.052856478871 -4.5721 -0.9852 2079860 MixCom4_000018 Fc1ccccc1c2cc(nc(n2)c3cccnc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A19 compound treatment 877160.0 -262000.0 -1.28 817670.0 -263000.0 -1.56 932440.0 -46401.5094339621 -0.265764293614341 -1.7961 -0.8808 2075083 MixCom4_000019 CN(C)/C=C/C(=O)c1sc(nc1C)c2c(Cl)cc(cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A20 compound treatment 758880.0 -380000.0 -1.86 734990.0 -346000.0 -2.06 872360.0 -106481.509433962 -0.609872038278849 -2.6123 -0.9205 2079861 MixCom4_000020 Fc1ccccc1c2cc(NC3CC3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A21 compound treatment 887320.0 -252000.0 -1.23 886410.0 -194000.0 -1.16 932510.0 -46331.5094339621 -0.265363369144858 -1.5312 -0.8958 2075084 MixCom4_000021 CN(C)/C(=N\O)/c1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A22 compound treatment 661620.0 -478000.0 -2.33 699960.0 -381000.0 -2.26 751630.0 -227211.509433962 -1.30135219828794 -3.4061 -0.9725 2079862 MixCom4_000022 OC1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A23 mock treatment 979800.0 -159000.0 -0.78 923710.0 -157000.0 -0.93 989370.0 10528.4905660379 0.0603018499234499 -0.9542 -0.7836 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 A24 mock treatment 916490.0 -223000.0 -1.09 814610.0 -266000.0 -1.58 900840.0 -78001.5094339621 -0.446753054123636 -1.8001 -0.9128 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B01 compound treatment 713970.0 -425000.0 -2.08 690260.0 -391000.0 -2.32 692290.0 -286551.509433962 -1.64122159856077 -3.488 -0.9904 2079863 MixCom4_000023 Cc1nc(NCc2ccncc2)cc(n1)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B02 compound treatment 960680.0 -179000.0 -0.87 909380.0 -171000.0 -1.02 872440.0 -106401.509433962 -0.609413838885155 -1.444 -0.9799 2075085 MixCom4_000024 CN(C)/C=C/C(=O)c1c(C)onc1c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B03 compound treatment 818770.0 -320000.0 -1.57 733240.0 -348000.0 -2.07 736720.0 -242121.509433962 -1.38674911028774 -2.8979 -0.9855 2079864 MixCom4_000025 Cc1nc(NCc2ccco2)cc(n1)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B04 compound treatment 892080.0 -247000.0 -1.21 877540.0 -203000.0 -1.21 831740.0 -147101.509433962 -0.84252278042719 -1.8814 -0.9876 2075086 MixCom4_000026 NC(=O)C1=CN(Cc2c(Cl)cccc2Cl)CCC1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B05 compound treatment 946920.0 -192000.0 -0.94 868430.0 -212000.0 -1.26 997180.0 18338.4905660379 0.105033565732868 -1.211 -0.7676 2079865 MixCom4_000027 FC(F)(F)Oc1ccc(cc1)c2cnc(nc2)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B06 compound treatment 1031110.0 -108000.0 -0.53 984560.0 -96200.0 -0.57 950030.0 -28811.5094339621 -0.16501770192578 -0.7307 -0.9178 1233106 MixCom4_000028 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(Br)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B07 compound treatment 1016290.0 -123000.0 -0.6 993710.0 -87100.0 -0.52 997250.0 18408.4905660379 0.10543449020235 -0.5849 -0.7311 2079866 MixCom4_000029 CN(C)CCNc1ccc(cc1F)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B08 mock treatment 1003650.0 -136000.0 -0.66 1003260.0 -77500.0 -0.46 949800.0 -29041.5094339621 -0.166335025182652 -0.7447 -0.9037 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B09 compound treatment 982580.0 -157000.0 -0.77 920110.0 -161000.0 -0.96 1057450.0 78608.4905660379 0.4502295339574 -0.7336 -0.5624 2079867 MixCom4_000030 CS(=O)(=O)c1ccc(NCc2ccccc2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B10 mock treatment 1012670.0 -127000.0 -0.62 973670.0 -107000.0 -0.64 953020.0 -25821.5094339621 -0.147892499586452 -0.8102 -0.9002 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B11 compound treatment 1008130.0 -131000.0 -0.64 964730.0 -116000.0 -0.69 942930.0 -35911.5094339621 -0.20568289811616 -0.8871 -0.9203 2079868 MixCom4_000031 CS(=O)(=O)c1ccc(cc1)N2CCC3(CC2)OCCO3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B12 compound treatment 852070.0 -287000.0 -1.4 826120.0 -255000.0 -1.51 756050.0 -222791.509433962 -1.27603668178632 -2.4211 -0.9976 2079908 MixCom4_000032 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)c4ccc(cc4)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B13 compound treatment 921700.0 -218000.0 -1.06 980680.0 -100000.0 -0.6 1000320.0 21478.4905660379 0.123017891935373 -0.8863 -0.7239 2079869 MixCom4_000033 CS(=O)(=O)c1ccc(NCCc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B14 compound treatment 915260.0 -224000.0 -1.09 960340.0 -120000.0 -0.72 952410.0 -26431.5094339621 -0.151386269963371 -1.1328 -0.8603 2079910 MixCom4_000034 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B15 compound treatment 1063200.0 -76000.0 -0.37 915780.0 -165000.0 -0.98 1019800.0 40958.4905660379 0.234589444299964 -0.6456 -0.6005 2079870 MixCom4_000035 CS(=O)(=O)c1ccc(N2CCN(CC2)C(=O)c3ccccc3)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B16 compound treatment 974720.0 -165000.0 -0.8 957790.0 -123000.0 -0.73 955520.0 -23321.5094339621 -0.133573768533501 -0.9635 -0.8799 2079915 MixCom4_000036 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B17 compound treatment 979520.0 -160000.0 -0.78 959210.0 -122000.0 -0.72 898640.0 -80201.5094339621 -0.459353537450233 -1.1332 -0.9779 2079871 MixCom4_000037 CC(=O)N1CCCN(CC1)c2ccc(cc2F)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B18 compound treatment 890490.0 -249000.0 -1.22 912520.0 -168000.0 -1.0 870140.0 -108701.509433962 -0.622587071453869 -1.6389 -0.9681 2079917 MixCom4_000038 CCCN1CCC(CC1)N(C(=O)c2cccs2)c3ccc4N(CCc4c3)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B19 compound treatment 991390.0 -148000.0 -0.72 922500.0 -158000.0 -0.94 959370.0 -19471.5094339621 -0.111522922711957 -1.0249 -0.86 2079872 MixCom4_000039 O=C(C1CCCCC1)N2CCc3nc4ccccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B20 compound treatment 635040.0 -504000.0 -2.46 591750.0 -489000.0 -2.91 695170.0 -283671.509433962 -1.62472642038777 -4.0393 -0.9749 2079919 MixCom4_000040 COc1cccc(OC)c1CN2CCC(CC2)N(C(=O)c3cccc(c3)C(F)(F)F)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B21 compound treatment 931240.0 -208000.0 -1.02 926000.0 -155000.0 -0.92 929040.0 -49801.5094339621 -0.285237767846354 -1.2829 -0.916 2079873 MixCom4_000041 CCC(=O)N1CCc2nc3ccccn3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B22 compound treatment 979230.0 -160000.0 -0.78 974920.0 -106000.0 -0.63 961690.0 -17151.5094339621 -0.0982351402948189 -0.8716 -0.8642 2079921 MixCom4_000042 OC(=O)C1N(Cc2ccccc2-n3cccc13)C4CCNCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B23 mock treatment 997720.0 -142000.0 -0.69 961790.0 -119000.0 -0.71 1025010.0 46168.4905660379 0.264429679814313 -0.6551 -0.6397 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 B24 mock treatment 1031680.0 -108000.0 -0.53 920510.0 -160000.0 -0.95 959680.0 -19161.5094339621 -0.109747400061391 -0.9171 -0.8383 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C01 compound treatment 646620.0 -493000.0 -2.41 605150.0 -476000.0 -2.83 579200.0 -399641.509433962 -2.28894371647205 -4.3441 -0.9958 2075090 MixCom4_000043 COc1ccc(CN2CCCN(Cc3ccc(OC)cc3)C2c4cccc(Cl)c4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C02 compound treatment 873410.0 -266000.0 -1.3 807630.0 -273000.0 -1.62 928270.0 -50571.5094339621 -0.289647937010662 -1.8549 -0.8834 2079874 MixCom4_000044 Cc1nc(NC2CC2)cc(n1)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C03 compound treatment 942820.0 -196000.0 -0.96 898420.0 -182000.0 -1.08 941390.0 -37451.5094339621 -0.214503236444778 -1.304 -0.8908 2075091 MixCom4_000045 CN1CCN(CC1)c2ccc(CNC(=O)C3CCC3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C04 compound treatment 647430.0 -492000.0 -2.4 609550.0 -471000.0 -2.8 579300.0 -399541.509433962 -2.28837096722993 -4.3264 -0.9961 2079875 MixCom4_000046 CCN(CC)c1cc(nc(n1)c2cccnc2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C05 compound treatment 961050.0 -178000.0 -0.87 908000.0 -173000.0 -1.03 928660.0 -50181.5094339621 -0.287414214966402 -1.2618 -0.9163 2075092 MixCom4_000047 CN1CCN(CC1)c2ccc(CNCC(O)C(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C06 compound treatment 724900.0 -414000.0 -2.02 846780.0 -234000.0 -1.39 790110.0 -188731.509433962 -1.08095828992092 -2.5963 -0.9674 2079876 MixCom4_000048 Fc1ccc(cc1)c2cc(NCc3ccco3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C07 compound treatment 969940.0 -169000.0 -0.83 913940.0 -167000.0 -0.99 1000120.0 21278.4905660379 0.121872393451137 -0.9801 -0.7553 2075093 MixCom4_000049 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3ccc(Cl)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C08 compound treatment 60050.0 -1080000.0 -5.27 36730.0 -1040000.0 -6.21 50730.0 -928111.509433962 -5.31575163629316 -9.6978 -0.997 2079877 MixCom4_000050 CN1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C09 compound treatment 998020.0 -141000.0 -0.69 943890.0 -137000.0 -0.81 991440.0 12598.4905660379 0.072157759235293 -0.8267 -0.7729 2075094 MixCom4_000051 CN1CCN(CC1)c2ccc(CNS(=O)(=O)C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C10 compound treatment 983920.0 -155000.0 -0.76 947620.0 -133000.0 -0.79 974170.0 -4671.50943396206 -0.0267560348784896 -0.9108 -0.8301 2079878 MixCom4_000052 COCCNc1cc(nc(C)n1)c2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C11 compound treatment 1263040.0 124000.0 0.6 1033690.0 -47100.0 -0.28 1177050.0 198208.490566038 1.13523762753056 0.8429 0.6403 2075095 MixCom4_000053 Cc1cc(CNCC(O)C(F)(F)F)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C12 compound treatment 852190.0 -287000.0 -1.4 831630.0 -249000.0 -1.48 932710.0 -46131.5094339621 -0.264217870660622 -1.8177 -0.8836 2079879 MixCom4_000054 Cc1nc(NCC=C)cc(n1)c2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C13 compound treatment 1067200.0 -72000.0 -0.35 1078650.0 -2140.0 -0.01 916350.0 -62491.5094339621 -0.357919646671131 -0.4172 -0.8308 2075096 MixCom4_000055 O=C(C1CCCCN1)N2CCN(Cc3cccnc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C14 compound treatment 827970.0 -311000.0 -1.52 828590.0 -252000.0 -1.5 825570.0 -153271.509433962 -0.877861408665872 -2.2508 -0.9747 2079880 MixCom4_000056 CC(Nc1cc(nc(C)n1)c2ccccc2F)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C15 compound treatment 905330.0 -234000.0 -1.14 866840.0 -214000.0 -1.27 856060.0 -122781.509433962 -0.703230164744087 -1.8004 -0.9736 2075097 MixCom4_000057 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C16 compound treatment 928970.0 -210000.0 -1.03 887840.0 -193000.0 -1.15 975800.0 -3041.50943396206 -0.0174202222319659 -1.2657 -0.8217 2079881 MixCom4_000058 CN(Cc1ccccc1)c2cc(nc(n2)c3ccccc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C17 compound treatment 709700.0 -430000.0 -2.1 674960.0 -406000.0 -2.41 625220.0 -353621.509433962 -2.02536451524933 -3.7743 -0.997 1575275 MixCom4_000059 Fc1ccc(cc1)C2NCCc3c2[nH]c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C18 compound treatment 1005840.0 -133000.0 -0.65 965000.0 -116000.0 -0.69 932210.0 -46631.5094339621 -0.267081616871212 -0.928 -0.9422 2079882 MixCom4_000060 Clc1ccc(cc1)c2cnc(nc2)N3CCN(Cc4ccccc4)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C19 compound treatment 591840.0 -547000.0 -2.67 596850.0 -484000.0 -2.88 591450.0 -387391.509433962 -2.21878193431259 -4.4866 -0.9944 2075098 MixCom4_000061 CN(C)/C=C/C(=O)c1ccc(o1)c2cc(ccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C20 compound treatment 99330.0 -1040000.0 -5.08 136710.0 -944000.0 -5.61 295940.0 -682901.509433962 -3.91131321969556 -8.4329 -0.9895 2079883 MixCom4_000062 CCN(CC)c1cc(nc(n1)c2ccncc2)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C21 compound treatment 524490.0 -615000.0 -3.0 360850.0 -720000.0 -4.28 439040.0 -539801.509433962 -3.09170905422467 -5.9909 -0.9861 2075099 MixCom4_000063 CSc1nc(nn1C(=O)N(C)C)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C22 compound treatment 463650.0 -676000.0 -3.3 517930.0 -563000.0 -3.35 580390.0 -398451.509433962 -2.28212800049084 -5.1558 -0.9866 2079884 MixCom4_000064 Fc1ccccc1c2cc(NCc3ccccc3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C23 mock treatment 991460.0 -148000.0 -0.72 992380.0 -88400.0 -0.53 988500.0 9658.49056603794 0.0553189315170231 -0.6885 -0.7693 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 C24 mock treatment 998080.0 -141000.0 -0.69 913660.0 -167000.0 -0.99 962840.0 -16001.5094339621 -0.0916485240104617 -1.0249 -0.8448 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D01 compound treatment 806030.0 -333000.0 -1.63 852920.0 -228000.0 -1.36 741760.0 -237081.509433962 -1.35788254848499 -2.5062 -0.9961 2079885 MixCom4_000065 Cc1nc(cc(n1)c2cccc(c2)C(F)(F)F)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D02 compound treatment 860870.0 -278000.0 -1.36 815610.0 -265000.0 -1.58 767040.0 -211801.509433962 -1.21309154007755 -2.3961 -0.9942 2075087 MixCom4_000066 CN(C)/C=C/C(=O)c1cc(no1)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D03 compound treatment 687070.0 -452000.0 -2.21 677010.0 -404000.0 -2.4 751280.0 -227561.509433962 -1.30335682063535 -3.4143 -0.9718 2079886 MixCom4_000067 CC(Nc1cc(nc(C)n1)c2cccc(c2)C(F)(F)F)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D04 compound treatment 985280.0 -154000.0 -0.75 943940.0 -137000.0 -0.81 971300.0 -7541.50943396206 -0.0431939381272769 -0.9291 -0.8377 1384637 MixCom4_000068 Clc1ccc(cc1)C(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D05 compound treatment 752030.0 -387000.0 -1.89 800410.0 -280000.0 -1.67 832010.0 -146831.509433962 -0.840976357473471 -2.5404 -0.9557 2079887 MixCom4_000069 C1CCN(C1)c2ncc(cn2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D06 compound treatment 1092370.0 -46900.0 -0.23 1482240.0 401000.0 2.39 1063400.0 84558.4905660379 0.484308113863422 1.5257 0.6236 1669460 MixCom4_000070 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D07 compound treatment 1012210.0 -127000.0 -0.62 1000000.0 -80800.0 -0.48 930640.0 -48201.5094339621 -0.276073779972465 -0.7951 -0.9556 2079888 MixCom4_000071 Cc1cnc(CNc2ccc(cc2F)S(=O)(=O)C)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D08 mock treatment 971280.0 -168000.0 -0.82 1008480.0 -72300.0 -0.43 944520.0 -34321.5094339621 -0.196576185166484 -0.8356 -0.8822 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D09 compound treatment 1060710.0 -78500.0 -0.38 955750.0 -125000.0 -0.74 983520.0 4678.49056603794 0.0267960192595455 -0.6354 -0.7589 2079889 MixCom4_000072 CS(=O)(=O)c1ccc(NCc2ccco2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D10 mock treatment 992320.0 -147000.0 -0.72 997500.0 -83300.0 -0.5 923620.0 -55221.5094339621 -0.31628077676915 -0.883 -0.9518 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D11 compound treatment 986180.0 -153000.0 -0.75 972320.0 -108000.0 -0.65 903680.0 -75161.5094339621 -0.430486975647484 -1.0527 -0.9771 2079890 MixCom4_000073 CS(=O)(=O)c1ccc(NCc2cccnc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D12 compound treatment 1322450.0 183000.0 0.9 957230.0 -124000.0 -0.73 1052420.0 73578.4905660379 0.421420247078864 0.3359 0.2726 2079923 MixCom4_000074 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D13 compound treatment 951210.0 -188000.0 -0.92 1078200.0 -2590.0 -0.02 914330.0 -64511.5094339621 -0.369489181361915 -0.7526 -0.76 2079891 MixCom4_000075 CS(=O)(=O)c1ccc(cc1)N2CCN(CC2)c3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D14 compound treatment 985660.0 -154000.0 -0.75 936770.0 -144000.0 -0.86 952320.0 -26521.5094339621 -0.151901744281278 -1.0154 -0.8839 2079925 MixCom4_000076 CC(=O)N1CCc2nc3cccc(C)n3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D15 compound treatment 1018280.0 -121000.0 -0.59 949730.0 -131000.0 -0.78 987770.0 8928.49056603794 0.0511378620495615 -0.7617 -0.7776 2079892 MixCom4_000077 CS(=O)(=O)c1ccc(N2CCN(CC2)C(=O)c3ccc(Cl)cc3)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D16 compound treatment 1075230.0 -64000.0 -0.31 975780.0 -105000.0 -0.62 902560.0 -76281.5094339621 -0.436901767159206 -0.7933 -0.963 2079938 MixCom4_000078 CCCN(C1CCN(C)CC1)C(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D17 compound treatment 1066310.0 -72900.0 -0.36 954670.0 -126000.0 -0.75 946160.0 -32681.5094339621 -0.187183097595748 -0.7468 -0.8774 2079893 MixCom4_000079 CS(=O)(=O)c1ccc(cc1)N2CCCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D18 compound treatment 945980.0 -193000.0 -0.94 795240.0 -286000.0 -1.7 927040.0 -51801.5094339621 -0.296692752688714 -1.6968 -0.8633 2079940 MixCom4_000080 CC(=O)N1CCc2cc(NC3CCN(Cc4ccccc4)CC3)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D19 compound treatment 1025870.0 -113000.0 -0.55 1026240.0 -54500.0 -0.32 900020.0 -78821.5094339621 -0.451449597909004 -0.7677 -0.9783 2079894 MixCom4_000081 Fc1cc(F)cc(CC(=O)N2CCc3nc4ccccn4c(=O)c3C2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D20 compound treatment 869960.0 -269000.0 -1.32 863490.0 -217000.0 -1.29 848190.0 -130651.509433962 -0.748305530098775 -1.9377 -0.9736 2079944 MixCom4_000082 FC(F)(F)c1cccc(CNC(=O)c2ccc(CCN3CCCC3)nc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D21 compound treatment 921000.0 -218000.0 -1.07 854280.0 -227000.0 -1.35 886260.0 -92581.5094339621 -0.530259893624444 -1.6994 -0.9452 2079895 MixCom4_000083 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)c4cccc(c4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D22 compound treatment 870670.0 -269000.0 -1.31 909920.0 -171000.0 -1.02 881710.0 -97131.5094339621 -0.556319984140814 -1.6654 -0.9515 2079946 MixCom4_000084 OC(=O)C1N(Cc2ccccc2)Cc3ccccc3-n4cccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D23 mock treatment 953780.0 -185000.0 -0.91 936560.0 -144000.0 -0.86 923410.0 -55431.5094339621 -0.317483550177598 -1.2016 -0.9334 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 D24 mock treatment 1055910.0 -83300.0 -0.41 1049490.0 -31300.0 -0.19 1037150.0 58308.4905660379 0.333961437807441 -0.1497 -0.2681 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E01 compound treatment 669140.0 -470000.0 -2.3 611610.0 -469000.0 -2.79 573660.0 -405181.509433962 -2.32067402448538 -4.2767 -0.9958 2075103 MixCom4_000085 COc1ccc(CN2CCCN(Cc3ccc(OC)cc3)C2c4ccsc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E02 compound treatment 435880.0 -703000.0 -3.44 347680.0 -733000.0 -4.36 554620.0 -424221.509433962 -2.42972548018466 -5.9038 -0.9743 2079896 MixCom4_000086 Cc1nc(NCCc2c[nH]c3ccccc23)cc(n1)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E03 compound treatment 1041800.0 -97400.0 -0.48 953670.0 -127000.0 -0.76 960160.0 -18681.5094339621 -0.106998203699225 -0.7731 -0.8592 2075104 MixCom4_000087 CN1CCN(CC1)c2ccc(CNC(=O)C3CCCCC3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E04 compound treatment 348540.0 -791000.0 -3.86 421240.0 -660000.0 -3.92 411730.0 -567111.509433962 -3.2481268722471 -6.3702 -0.9966 2079897 MixCom4_000088 Fc1ccc(cc1)c2cc(nc(n2)c3cccnc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E05 compound treatment 1083750.0 -55500.0 -0.27 961850.0 -119000.0 -0.71 1011580.0 32738.4905660379 0.187509456597863 -0.4566 -0.5852 2075105 MixCom4_000089 OC(CN1CCCN(CC1)c2nccc(n2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E06 compound treatment 886890.0 -252000.0 -1.23 745330.0 -335000.0 -1.99 987390.0 8548.49056603794 0.048961414929513 -1.8353 -0.7824 2079898 MixCom4_000090 Fc1ccc(cc1)c2cc(NCc3ccc(Cl)cc3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E07 compound treatment 1057700.0 -81500.0 -0.4 850080.0 -231000.0 -1.37 948920.0 -29921.5094339621 -0.17137521851329 -1.1211 -0.7791 2075106 MixCom4_000091 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3cc(F)ccc3C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E08 compound treatment 696860.0 -442000.0 -2.16 685640.0 -395000.0 -2.35 725210.0 -253631.509433962 -1.45267254805552 -3.4432 -0.9816 2079899 MixCom4_000092 Fc1ccc(cc1)c2cc(NCc3ccccc3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E09 compound treatment 1098880.0 -40400.0 -0.2 995040.0 -85700.0 -0.51 987850.0 9008.49056603794 0.051596061443256 -0.3785 -0.6892 2075107 MixCom4_000093 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3ccsc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E10 compound treatment 966880.0 -172000.0 -0.84 1023210.0 -57600.0 -0.34 960960.0 -17881.5094339621 -0.102416209762281 -0.743 -0.8122 2079900 MixCom4_000094 Cc1nc(cc(n1)c2ccccc2F)N3CCC4(CC3)OCCO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E11 compound treatment 1129250.0 -10000.0 -0.05 1053870.0 -26900.0 -0.16 966180.0 -12661.5094339621 -0.0725186993237197 -0.1625 -0.8908 2075108 MixCom4_000095 OC(CN1CCCN(Cc2ccc(F)cc2)CC1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E12 compound treatment 1101540.0 -37700.0 -0.18 991840.0 -88900.0 -0.53 1155860.0 177018.490566038 1.01387206312575 0.1736 0.1499 2079901 MixCom4_000096 CN1CCN(CC1)c2cc(nc(C)n2)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E13 compound treatment 1297920.0 159000.0 0.78 1362820.0 282000.0 1.68 1071270.0 92428.4905660379 0.529383479218111 1.7215 0.8957 2075109 MixCom4_000097 Clc1c(sc2ccccc12)C(=O)N3CCN(Cc4cccnc4)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E14 compound treatment 846760.0 -292000.0 -1.43 742980.0 -338000.0 -2.01 839540.0 -139301.509433962 -0.797848339541984 -2.4455 -0.9438 2079902 MixCom4_000098 Cc1nc(NC2CCCCC2)cc(n1)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E15 compound treatment 1039950.0 -99300.0 -0.49 1016440.0 -64300.0 -0.38 926630.0 -52211.5094339621 -0.299041024581398 -0.6737 -0.9814 2075110 MixCom4_000099 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E16 compound treatment 54400.0 -1080000.0 -5.3 119310.0 -961000.0 -5.72 228670.0 -750171.509433962 -4.29660163486835 -8.8418 -0.9932 2079903 MixCom4_000100 CN1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E17 compound treatment 1001520.0 -138000.0 -0.67 991760.0 -89000.0 -0.53 894560.0 -84281.5094339621 -0.482721706528648 -0.9729 -0.9898 2075111 MixCom4_000101 ClC1=C(CN2CCSCC2)CSc3ccc(Cl)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E18 compound treatment 906600.0 -233000.0 -1.14 823060.0 -258000.0 -1.53 750600.0 -228241.509433962 -1.30725151548175 -2.2958 -0.9926 2079904 MixCom4_000102 CN(Cc1ccccc1)c2cc(nc(n2)c3cccnc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E19 compound treatment 782670.0 -357000.0 -1.74 895360.0 -185000.0 -1.1 790900.0 -187941.509433962 -1.07643357090819 -2.2639 -0.9734 2075112 MixCom4_000103 CN1CCN(CC1)c2ccccc2/C=C\3/C(=O)Nc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E20 compound treatment 674360.0 -465000.0 -2.27 670660.0 -410000.0 -2.44 616000.0 -362841.509433962 -2.07817199537261 -3.9193 -0.9979 2079905 MixCom4_000104 Fc1ccccc1c2cc(NCc3ccncc3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E21 compound treatment 1042270.0 -97000.0 -0.47 951360.0 -129000.0 -0.77 918880.0 -59961.5094339621 -0.343429090845545 -0.9162 -0.9476 2075113 MixCom4_000105 CN(C)/C=C/C(=O)c1nn(ccc1=O)c2ccc(cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E22 compound treatment 265060.0 -874000.0 -4.27 376800.0 -704000.0 -4.19 460880.0 -517961.509433962 -2.96662061974609 -6.5957 -0.988 2079906 MixCom4_000106 Fc1ccccc1c2cc(NCc3ccco3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E23 mock treatment 1021150.0 -118000.0 -0.58 1091890.0 11100.0 0.07 1000330.0 21488.4905660379 0.123075166859585 -0.224 -0.3773 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 E24 mock treatment 954500.0 -185000.0 -0.9 1237770.0 157000.0 0.93 977400.0 -1441.50943396206 -0.00825623435807748 0.0131 0.0101 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F01 compound treatment 742160.0 -397000.0 -1.94 894780.0 -186000.0 -1.11 777970.0 -200871.509433962 -1.15049004791405 -2.423 -0.9645 2079907 MixCom4_000107 Cc1nc(cc(n1)c2cccc(c2)C(F)(F)F)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F02 compound treatment 1074360.0 -64900.0 -0.32 1079540.0 -1250.0 -0.01 901250.0 -77591.5094339621 -0.444404782230952 -0.4439 -0.8131 2075088 MixCom4_000108 Fc1ccc(cc1Cl)S(=O)(=O)NN2C3CSC2CS3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F03 compound treatment 434610.0 -705000.0 -3.44 542720.0 -538000.0 -3.2 590770.0 -388071.509433962 -2.22267662915899 -5.1182 -0.9845 2079909 MixCom4_000109 Cc1nc(NCc2ccc(Cl)cc2)cc(n1)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F04 compound treatment 1082720.0 -56500.0 -0.28 946900.0 -134000.0 -0.8 962750.0 -16091.5094339621 -0.0921639983283679 -0.6723 -0.7931 1214022 MixCom4_000110 Cc1ccc(cc1)C(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F05 compound treatment 804430.0 -335000.0 -1.64 801920.0 -279000.0 -1.66 844000.0 -134841.509433962 -0.77230372334352 -2.3478 -0.9567 2079911 MixCom4_000111 Fc1ccc(cc1)c2cnc(nc2)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F06 mock treatment 1181760.0 42500.0 0.21 1034780.0 -46000.0 -0.27 978720.0 -121.509433962055 -6.95944362119573E-4 -0.0384 -0.1119 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F07 compound treatment 1069370.0 -69900.0 -0.34 965500.0 -115000.0 -0.69 954020.0 -24821.5094339621 -0.142165007165271 -0.675 -0.8665 2079912 MixCom4_000112 CC(C)N(C(C)C)c1ccc(cc1F)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F08 mock treatment 1073800.0 -65400.0 -0.32 1040010.0 -40800.0 -0.24 979090.0 248.490566037945 0.00142322783371711 -0.3238 -0.8068 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F09 compound treatment 958640.0 -181000.0 -0.88 894320.0 -186000.0 -1.11 824860.0 -153981.509433962 -0.88192792828491 -1.6588 -0.9938 2079913 MixCom4_000113 CS(=O)(=O)c1ccc(N2CCc3ccccc3C2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F10 mock treatment 1084890.0 -54400.0 -0.27 1028270.0 -52500.0 -0.31 941190.0 -37651.5094339621 -0.215648734929014 -0.4581 -0.9891 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F11 compound treatment 995800.0 -143000.0 -0.7 995270.0 -85500.0 -0.51 939430.0 -39411.5094339621 -0.225729121590291 -0.8286 -0.9259 2079914 MixCom4_000114 CS(=O)(=O)c1ccc(cc1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F12 compound treatment 1276000.0 137000.0 0.67 922000.0 -159000.0 -0.94 1017140.0 38298.4905660379 0.219354314459625 -0.0328 -0.0278 2079948 MixCom4_000115 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F13 compound treatment 1080520.0 -58700.0 -0.29 1030670.0 -50100.0 -0.3 985840.0 6998.49056603794 0.0400838016766837 -0.3146 -0.7569 2079916 MixCom4_000116 CC(Nc1ccc(cc1)S(=O)(=O)C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F14 compound treatment 1052760.0 -86500.0 -0.42 968390.0 -112000.0 -0.67 912500.0 -66341.5094339621 -0.379970492492675 -0.8492 -0.968 2079950 MixCom4_000117 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)c4ccc(Cl)cc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F15 compound treatment 1130650.0 -8600.0 -0.04 1016040.0 -64700.0 -0.39 955600.0 -23241.5094339621 -0.133115569139807 -0.3234 -0.7896 2079918 MixCom4_000118 CS(=O)(=O)c1ccc(N2CCN(CC2)C(=O)c3c(F)cccc3F)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F16 compound treatment 1013660.0 -126000.0 -0.61 984690.0 -96100.0 -0.57 919460.0 -59381.5094339621 -0.34010714524126 -0.8805 -0.9732 2079952 MixCom4_000119 Fc1c(F)c(F)c2c(CC(=O)NCCN3CCOCC3)c[nH]c2c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F17 compound treatment 996810.0 -142000.0 -0.7 956880.0 -124000.0 -0.74 1113540.0 134698.490566038 0.771484583861399 -0.3818 -0.2997 2079920 MixCom4_000120 CS(=O)(=O)c1ccc(cc1)N2CCCC(O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F18 compound treatment 996850.0 -142000.0 -0.7 1097610.0 16800.0 0.1 896060.0 -82781.5094339621 -0.474130467896878 -0.6177 -0.7285 2079726 MixCom4_000121 OC(=O)C1CCN(Cc2ccccn2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F19 compound treatment 988320.0 -151000.0 -0.74 1059580.0 -21200.0 -0.13 933850.0 -44991.5094339621 -0.257688529300477 -0.6473 -0.8181 2079922 MixCom4_000122 CC(C)CC(=O)N1CCc2nc3ccccn3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F20 compound treatment 796410.0 -343000.0 -1.68 936480.0 -144000.0 -0.86 816980.0 -161861.509433962 -0.92706056856381 -1.9978 -0.9522 2079966 MixCom4_000123 Clc1ccc(cc1)c2csc(c2)C(=O)NCCN3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F21 compound treatment 987880.0 -151000.0 -0.74 978310.0 -102000.0 -0.61 920480.0 -58361.5094339621 -0.334265102971656 -0.9718 -0.9575 2079924 MixCom4_000124 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F22 compound treatment 1097040.0 -42200.0 -0.21 1026340.0 -54400.0 -0.32 955740.0 -23101.5094339621 -0.132313720200841 -0.3824 -0.9417 2079734 MixCom4_000125 OC(=O)C1CCN(Cc2ccncc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F23 mock treatment 1169500.0 30300.0 0.15 1158340.0 77600.0 0.46 990780.0 11938.4905660379 0.068377614237314 0.3911 0.7996 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 F24 mock treatment 1153450.0 14200.0 0.07 971520.0 -109000.0 -0.65 950270.0 -28571.5094339621 -0.163643103744697 -0.4296 -0.6377 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G01 compound treatment 676800.0 -462000.0 -2.26 575450.0 -505000.0 -3.01 487370.0 -491471.509433962 -2.81489934550903 -4.6646 -0.9932 2075114 MixCom4_000126 COc1ccc(CN2CCCN(Cc3ccc(OC)cc3)C2c4cccnc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G02 compound treatment 860010.0 -279000.0 -1.36 686030.0 -395000.0 -2.35 745650.0 -233191.509433962 -1.3356026029666 -2.9141 -0.9631 2079926 MixCom4_000127 Fc1ccc(cc1)c2cc(nc(n2)c3ccccc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G03 compound treatment 1077450.0 -61800.0 -0.3 995620.0 -85200.0 -0.51 894890.0 -83951.5094339621 -0.480831634029658 -0.7443 -0.9783 2075115 MixCom4_000128 CN1CCN(CC1)c2ccc(CNC(=O)c3ccco3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G04 compound treatment 724320.0 -415000.0 -2.03 732570.0 -348000.0 -2.07 719890.0 -258951.509433962 -1.4831428077362 -3.2223 -0.9898 2079927 MixCom4_000129 Fc1ccc(cc1)c2cc(nc(n2)c3cccnc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G05 compound treatment 1033630.0 -106000.0 -0.52 1028030.0 -52800.0 -0.31 899890.0 -78951.5094339621 -0.452194171923757 -0.7401 -0.981 2075116 MixCom4_000130 OC(CN1CCCc2cc(ccc12)C(=O)O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G06 compound treatment 878560.0 -261000.0 -1.27 885130.0 -196000.0 -1.16 779140.0 -199701.509433962 -1.14378888178127 -2.0675 -0.9989 2079928 MixCom4_000131 Fc1ccc(cc1)c2cc(NC3CC3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G07 compound treatment 1089860.0 -49400.0 -0.24 1110940.0 30200.0 0.18 891270.0 -87571.5094339621 -0.501565156594331 -0.3254 -0.5564 2075117 MixCom4_000132 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3ccc(F)cc3Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G08 compound treatment 563690.0 -576000.0 -2.81 873820.0 -207000.0 -1.23 739150.0 -239691.509433962 -1.37283130370427 -3.1267 -0.9299 2079929 MixCom4_000133 Fc1ccc(cc1)c2cc(NCc3ccco3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G09 compound treatment 1106160.0 -33100.0 -0.16 1030490.0 -50300.0 -0.3 972110.0 -6731.50943396206 -0.0385546692661209 -0.2883 -0.8425 2075118 MixCom4_000134 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3cc(C)sc3C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G10 compound treatment 841850.0 -297000.0 -1.45 900680.0 -180000.0 -1.07 839360.0 -139481.509433962 -0.798879288177797 -1.9185 -0.9719 2079930 MixCom4_000135 CCN(CC)c1cc(nc(C)n1)c2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G11 compound treatment 1111360.0 -27900.0 -0.14 1023490.0 -57300.0 -0.34 954670.0 -24171.5094339621 -0.138442137091504 -0.3553 -0.9059 2075119 MixCom4_000136 OC(CN1CCN(Cc2c(F)cccc2Cl)CC1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G12 compound treatment 1427530.0 288000.0 1.41 1092700.0 11900.0 0.07 1216830.0 237988.490566038 1.36307727604511 1.6411 0.8367 2079931 MixCom4_000137 Cc1nc(cc(n1)c2ccccc2F)N3CCC(O)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G13 compound treatment 978340.0 -161000.0 -0.79 1209550.0 129000.0 0.77 917990.0 -60851.5094339621 -0.348526559100395 -0.213 -0.185 2075120 MixCom4_000138 O=C(N1CCSCC1)c2nc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G14 compound treatment 873830.0 -265000.0 -1.3 895810.0 -185000.0 -1.1 787300.0 -191541.509433962 -1.09705254362444 -2.0172 -0.9968 2079932 MixCom4_000139 Cc1nc(NC2CC2)cc(n1)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G15 compound treatment 1003450.0 -136000.0 -0.66 975270.0 -106000.0 -0.63 820880.0 -157961.509433962 -0.904723348121207 -1.2677 -0.9862 1461440 MixCom4_000140 COc1cc2CCN(Cc2cc1OC)S(=O)(=O)c3ccc(F)c(F)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G16 compound treatment 220800.0 -918000.0 -4.49 333470.0 -747000.0 -4.44 183450.0 -795391.509433962 -4.55559884215412 -7.7867 -0.9999 2079933 MixCom4_000141 OC1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G17 compound treatment 296130.0 -843000.0 -4.12 341780.0 -739000.0 -4.39 284240.0 -694601.509433962 -3.97832488102337 -7.2124 -0.9991 2075121 MixCom4_000142 ClC1=C(CN2CCCCC2)CSc3ccc(Cl)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G18 compound treatment 757890.0 -381000.0 -1.86 814400.0 -266000.0 -1.58 739170.0 -239671.509433962 -1.37271675385584 -2.7829 -0.9923 2079934 MixCom4_000143 Fc1ccccc1c2cc(NCC=C)nc(n2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G19 compound treatment 818350.0 -321000.0 -1.57 655160.0 -426000.0 -2.53 484500.0 -494341.509433962 -2.83133724875781 -4.0012 -0.9738 2075122 MixCom4_000144 CN1CCN(CC1)c2ccccc2/C=N/c3cc(Cl)cc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G20 compound treatment 471360.0 -668000.0 -3.26 454480.0 -626000.0 -3.72 519290.0 -459551.509433962 -2.63207778742495 -5.5539 -0.9904 2079935 MixCom4_000145 Fc1ccccc1c2cc(nc(n2)c3ccncc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G21 compound treatment 1020930.0 -118000.0 -0.58 999690.0 -81100.0 -0.48 957560.0 -21281.5094339621 -0.121889683994293 -0.6826 -0.895 2075123 MixCom4_000146 COCc1cc(nc(n1)c2csc(C)n2)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G22 compound treatment 538400.0 -601000.0 -2.94 622280.0 -459000.0 -2.73 590800.0 -388041.509433962 -2.22250480438636 -4.5522 -0.9936 2079936 MixCom4_000147 CC(Nc1cc(nc(n1)c2ccncc2)c3ccccc3F)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G23 mock treatment 1109830.0 -29400.0 -0.14 1068280.0 -12500.0 -0.07 904800.0 -74041.5094339621 -0.424072184135762 -0.3708 -0.8168 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 G24 mock treatment 1144560.0 5310.0 0.03 1172800.0 92000.0 0.55 965120.0 -13721.5094339621 -0.0785898412901707 0.2855 0.516 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H01 compound treatment 886330.0 -253000.0 -1.24 958560.0 -122000.0 -0.73 736520.0 -242321.509433962 -1.38789460877197 -1.9344 -0.9694 2079937 MixCom4_000148 CN(Cc1ccccc1)c2cc(nc(C)n2)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H02 compound treatment 1409650.0 270000.0 1.32 1224120.0 143000.0 0.85 1164260.0 185418.490566038 1.06198299946366 1.868 0.9846 2075089 MixCom4_000149 FC(F)(F)C1CCN(CC1)c2ccc(cc2NC(=O)c3cccs3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H03 compound treatment 684840.0 -454000.0 -2.22 646460.0 -434000.0 -2.58 737710.0 -241131.509433962 -1.38107889279077 -3.5703 -0.9715 2079939 MixCom4_000150 Cc1nc(NC2CC2)cc(n1)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H04 compound treatment 1069620.0 -69600.0 -0.34 1023570.0 -57200.0 -0.34 988960.0 10118.4905660379 0.057953578030766 -0.3594 -0.7416 1510899 MixCom4_000151 O=C(N1CCN(Cc2ccc3OCOc3c2)CC1)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H05 compound treatment 1081690.0 -57600.0 -0.28 1042720.0 -38100.0 -0.23 991120.0 12278.4905660379 0.0703249616605153 -0.2525 -0.6864 1653366 MixCom4_000152 OC(=O)CC1(CC(=O)NC2CC2)CCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H06 mock treatment 1048520.0 -90700.0 -0.44 1066200.0 -14600.0 -0.09 896800.0 -82041.5094339621 -0.469892123505204 -0.5773 -0.8857 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H07 compound treatment 1192990.0 53700.0 0.26 1094770.0 14000.0 0.08 931740.0 -47101.5094339621 -0.269773538309167 0.0439 0.1137 2079941 MixCom4_000153 CS(=O)(=O)c1ccc(N2CCC3(CC2)OCCO3)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H08 mock treatment 1109840.0 -29400.0 -0.14 1092880.0 12100.0 0.07 888800.0 -90041.5094339621 -0.515712062874646 -0.3392 -0.6279 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H09 compound treatment 1054400.0 -84800.0 -0.41 1110020.0 29200.0 0.17 834100.0 -144741.509433962 -0.829005898313205 -0.6176 -0.6549 2079942 MixCom4_000154 CS(=O)(=O)c1ccc(NCCc2ccccc2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H10 mock treatment 1125530.0 -13700.0 -0.07 1124640.0 43900.0 0.26 1011520.0 32678.4905660379 0.187165807052592 0.2199 0.6707 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H11 compound treatment 1355740.0 216000.0 1.06 1074470.0 -6320.0 -0.04 910160.0 -68681.5094339621 -0.393372824758236 0.3619 0.3205 2079943 MixCom4_000155 CS(=O)(=O)c1ccc(cc1)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H12 compound treatment 1254740.0 115000.0 0.56 1133500.0 52700.0 0.31 1150340.0 171498.490566038 0.982256304960832 1.0739 0.9136 2079972 MixCom4_000156 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)c4c(F)cccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H13 compound treatment 1076870.0 -62400.0 -0.3 1419140.0 338000.0 2.01 901930.0 -76911.5094339621 -0.44051008738455 0.7314 0.3513 2079945 MixCom4_000157 CC1CN(CC(C)O1)c2ccc(cc2)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H14 compound treatment 1093350.0 -45900.0 -0.22 976030.0 -105000.0 -0.62 903060.0 -75781.5094339621 -0.434038020948616 -0.7397 -0.9344 2079974 MixCom4_000158 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)Cc4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H15 compound treatment 1109790.0 -29500.0 -0.14 1182360.0 102000.0 0.6 934280.0 -44561.5094339621 -0.255225707559369 0.1183 0.1762 2079947 MixCom4_000159 CS(=O)(=O)c1ccc(cc1)N2CCC(O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H16 compound treatment 1349540.0 210000.0 1.03 1094000.0 13200.0 0.08 1049920.0 71078.4905660379 0.407101516025913 0.8736 0.7885 2079653 MixCom4_000160 O=C1Cc2ccccc2N1C3CCN(CCC#N)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H17 compound treatment 1012450.0 -127000.0 -0.62 1412190.0 331000.0 1.97 923100.0 -55741.5094339621 -0.319259072828164 0.5958 0.285 2079949 MixCom4_000161 CS(=O)(=O)c1ccc(N2CCCC(O)C2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H18 compound treatment 1113140.0 -26100.0 -0.13 1010290.0 -70500.0 -0.42 956000.0 -22841.5094339621 -0.130824572171334 -0.3912 -0.8555 2079977 MixCom4_000162 C1CN(CCO1)C2c3cccn3-c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H19 compound treatment 955170.0 -184000.0 -0.9 897250.0 -184000.0 -1.09 759580.0 -219261.509433962 -1.25581863353956 -1.8744 -0.9911 2079951 MixCom4_000163 CC(C)(C)c1ccc(cc1)C(=O)N2CCc3nc4ccccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H20 compound treatment 864550.0 -275000.0 -1.34 989920.0 -90900.0 -0.54 838790.0 -140051.509433962 -0.802143958857869 -1.55 -0.9369 2079979 MixCom4_000164 CN1CCN(CC1)C(=O)c2cc(cs2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H21 compound treatment 1082580.0 -56700.0 -0.28 978610.0 -102000.0 -0.61 924390.0 -54451.5094339621 -0.311870607604842 -0.6907 -0.9372 2079953 MixCom4_000165 CC(=O)N1CCc2nc3c(C)cccn3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H22 compound treatment 1201810.0 62600.0 0.31 958020.0 -123000.0 -0.73 861400.0 -117441.509433962 -0.672645355214984 -0.6334 -0.6098 2079981 MixCom4_000166 CN1CCC(CC1)N(C(=O)c2ccc(cc2)C(F)(F)F)c3ccc4CCN(C(=O)C)c4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H23 mock treatment 1280770.0 142000.0 0.69 1093070.0 12300.0 0.07 988980.0 10138.4905660379 0.0580681278791896 0.4749 0.6806 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 H24 mock treatment 1220050.0 80800.0 0.39 1155570.0 74800.0 0.44 1018790.0 39948.4905660379 0.228804676954572 0.6168 0.968 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I01 compound treatment 1005220.0 -134000.0 -0.65 1105860.0 25100.0 0.15 846240.0 -132601.509433962 -0.759474140320077 -0.7305 -0.7205 2075124 MixCom4_000167 COc1ccc(CC(=O)Nc2ccccc2N3CCCCC3)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I02 compound treatment 1276410.0 137000.0 0.67 991280.0 -89500.0 -0.53 935780.0 -43061.5094339621 -0.246634468927599 -0.0628 -0.0705 2079954 MixCom4_000168 Fc1ccc(cc1)c2cc(nc(n2)c3ccccc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I03 compound treatment 907270.0 -232000.0 -1.13 822890.0 -258000.0 -1.53 906420.0 -72421.5094339621 -0.41479364641345 -1.7793 -0.9117 2075125 MixCom4_000169 CN1CCN(CC1)c2ccc(CNC(=O)c3cc4ccccc4o3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I04 compound treatment 1018600.0 -121000.0 -0.59 787440.0 -293000.0 -1.74 715870.0 -262971.509433962 -1.50616732726934 -2.217 -0.932 2079955 MixCom4_000170 CN(Cc1ccccc1)c2cc(nc(n2)c3cccnc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I05 compound treatment 1050460.0 -88800.0 -0.43 1050420.0 -30400.0 -0.18 1074100.0 95258.4905660379 0.545592282770051 -0.0397 -0.0552 2075126 MixCom4_000171 OC(CN1CCN(Cc2ccc3OCOc3c2)CC1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I06 compound treatment 255850.0 -883000.0 -4.32 390880.0 -690000.0 -4.1 395360.0 -583481.509433962 -3.34188592318182 -6.79 -0.9944 2079956 MixCom4_000172 CCN(CC)c1cc(nc(n1)c2ccncc2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I07 compound treatment 966830.0 -172000.0 -0.84 975090.0 -106000.0 -0.63 894420.0 -84421.5094339621 -0.483523555467613 -1.1284 -0.9753 2075127 MixCom4_000173 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3cccc(F)c3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I08 compound treatment 461380.0 -678000.0 -3.31 377400.0 -703000.0 -4.18 442320.0 -536521.509433962 -3.0729228790832 -6.1012 -0.991 2079957 MixCom4_000174 Fc1ccc(cc1)c2cc(NCc3ccc(Cl)cc3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I09 compound treatment 1093300.0 -45900.0 -0.22 1059480.0 -21300.0 -0.13 1004480.0 25638.4905660379 0.146844260407483 -0.118 -0.3977 2075128 MixCom4_000175 OC(CNC1CCN(Cc2ccccc2)CC1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I10 compound treatment 827040.0 -312000.0 -1.53 780080.0 -301000.0 -1.79 713210.0 -265631.509433962 -1.52140245710968 -2.7915 -0.997 2079958 MixCom4_000176 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c3ccc4[nH]c(C)cc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I11 compound treatment 1008930.0 -130000.0 -0.64 1431740.0 351000.0 2.09 909320.0 -69521.5094339621 -0.398183918392028 0.6074 0.2739 2075129 MixCom4_000177 OC(CN1CCN(CC1)c2ccc(F)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I12 compound treatment 1142750.0 3500.0 0.02 920970.0 -160000.0 -0.95 983680.0 4838.49056603794 0.0277124180469344 -0.5228 -0.5498 2079959 MixCom4_000178 Cc1nc(NCc2ccccc2)cc(n1)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I13 compound treatment 1068610.0 -70600.0 -0.35 1073180.0 -7610.0 -0.05 808920.0 -169921.509433962 -0.973224157478523 -0.7873 -0.7617 2075130 MixCom4_000179 O=C(Nc1ccccc1N2CCOCC2)c3nc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I14 compound treatment 725400.0 -414000.0 -2.02 711390.0 -369000.0 -2.2 824730.0 -154111.509433962 -0.882672502299664 -2.9452 -0.946 2079960 MixCom4_000180 Cc1nc(NCCc2c[nH]c3ccccc23)cc(n1)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I15 compound treatment 411000.0 -728000.0 -3.56 989610.0 -91200.0 -0.54 922880.0 -55961.5094339621 -0.320519121160824 -2.5523 -0.7064 2075131 MixCom4_000181 O=C1C2CCN(CC2)C31CC3c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I16 compound treatment 44280.0 -1090000.0 -5.35 37790.0 -1040000.0 -6.2 38120.0 -940721.509433962 -5.38797531572425 -9.7803 -0.9976 2079961 MixCom4_000182 CCCN1CCC(CC1)N(C2CC2)C(=O)c3cccc(NC(=O)c4ccc(cc4)C(C)(C)C)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I17 compound treatment 1163360.0 24100.0 0.12 990200.0 -90600.0 -0.54 904250.0 -74591.5094339621 -0.427222304967411 -0.4896 -0.7019 2075132 MixCom4_000183 CCN(CC)C(=O)c1cc2sccc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I18 compound treatment 310660.0 -829000.0 -4.05 314910.0 -766000.0 -4.55 532050.0 -446791.509433962 -2.55899498413069 -6.4442 -0.9751 2079962 MixCom4_000184 CN1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I19 compound treatment 1194130.0 54900.0 0.27 1156720.0 75900.0 0.45 1019570.0 40728.4905660379 0.233272121043093 0.5502 0.9575 2075133 MixCom4_000185 Cc1c(C)c(C)c(CS/C(=N/c2cc(Cl)ccc2Cl)/N3CCOCC3)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I20 compound treatment 98670.0 -1040000.0 -5.08 206330.0 -874000.0 -5.2 255360.0 -723481.509433962 -4.14373486214705 -8.3299 -0.9952 2079963 MixCom4_000186 Fc1ccccc1c2cc(nc(n2)c3ccncc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I21 compound treatment 931970.0 -207000.0 -1.01 808690.0 -272000.0 -1.62 773810.0 -205031.509433962 -1.17431641638616 -2.1969 -0.9802 2075134 MixCom4_000187 COC(=O)c1c(/C=C/N(C)C)onc1c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I22 compound treatment 729600.0 -410000.0 -2.0 770660.0 -310000.0 -1.84 586880.0 -391961.509433962 -2.24495657467738 -3.5164 -0.9967 2079964 MixCom4_000188 Fc1ccccc1c2cc(NC3CC3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I23 mock treatment 1285210.0 146000.0 0.71 1289200.0 208000.0 1.24 972990.0 -5851.50943396206 -0.0335144759354823 1.1079 0.7746 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 I24 mock treatment 1204020.0 64800.0 0.32 1140800.0 60000.0 0.36 931460.0 -47381.5094339621 -0.271377236187097 0.2321 0.4229 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J01 compound treatment 695320.0 -444000.0 -2.17 669630.0 -411000.0 -2.44 726360.0 -252481.509433962 -1.44608593177116 -3.4987 -0.9789 2079965 MixCom4_000189 Cc1nc(NCC=C)cc(n1)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J02 compound treatment 620670.0 -519000.0 -2.53 499530.0 -581000.0 -3.46 627310.0 -351531.509433962 -2.01339405608906 -4.6209 -0.9759 2075100 MixCom4_000190 COc1ccc(NC(=O)Nc2cc(ccc2N3CCC(CC3)C(F)(F)F)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J03 compound treatment 753630.0 -386000.0 -1.88 904350.0 -176000.0 -1.05 839960.0 -138881.509433962 -0.795442792725089 -2.1528 -0.9366 2079967 MixCom4_000191 FC(F)(F)c1cccc(c1)c2cc(NC3CC3)nc(n2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J04 compound treatment 1412250.0 273000.0 1.33 1180340.0 99600.0 0.59 1063580.0 84738.4905660379 0.485339062499235 1.3921 0.9052 1151412 MixCom4_000192 CC(C)(C)C(=O)N1CCN(Cc2ccc3OCOc3c2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J05 compound treatment 1250900.0 112000.0 0.55 1136980.0 56200.0 0.33 920640.0 -58201.5094339621 -0.333348704184267 0.3154 0.4372 2079968 MixCom4_000193 CNC(=O)CC1(CC(=O)O)CCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J06 mock treatment 1117080.0 -22200.0 -0.11 1100510.0 19700.0 0.12 988480.0 9638.49056603794 0.0552043816685995 0.0371 0.2194 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J07 compound treatment 1042590.0 -96700.0 -0.47 1130720.0 49900.0 0.3 987760.0 8918.49056603794 0.0510805871253497 -0.0717 -0.1281 2079969 MixCom4_000194 CS(=O)(=O)c1ccc(NCc2cccnc2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J08 mock treatment 1131680.0 -7570.0 -0.04 1075000.0 -5790.0 -0.03 1015420.0 36578.4905660379 0.209503027495195 0.0797 0.37 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J09 compound treatment 1095860.0 -43400.0 -0.21 974310.0 -106000.0 -0.63 953960.0 -24881.5094339621 -0.142508656710542 -0.5702 -0.8352 2079970 MixCom4_000195 CS(=O)(=O)c1ccc(N2CCN(CC2)c3ccccn3)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J10 mock treatment 1136990.0 -2260.0 -0.01 1084080.0 3290.0 0.02 914690.0 -64151.5094339621 -0.36742728409029 -0.2072 -0.5629 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J11 compound treatment 1225850.0 86600.0 0.42 1104650.0 23900.0 0.14 946500.0 -32341.5094339621 -0.185235750172547 0.2193 0.4538 2079971 MixCom4_000196 CN1CCN(CC1)c2ccc(cc2)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J12 compound treatment 1129600.0 -9650.0 -0.05 1137470.0 56700.0 0.34 968170.0 -10671.5094339621 -0.061120989405571 0.1321 0.382 2079994 MixCom4_000197 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J13 compound treatment 1401560.0 262000.0 1.28 1071360.0 -9430.0 -0.06 1124870.0 146028.490566038 0.836377072993371 1.1905 0.7774 2079973 MixCom4_000198 CS(=O)(=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J14 compound treatment 1120650.0 -18600.0 -0.09 1308160.0 227000.0 1.35 865600.0 -113241.509433962 -0.648589887046027 0.3537 0.2354 2079996 MixCom4_000199 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)C4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J15 compound treatment 1137990.0 -1260.0 -0.01 1184810.0 104000.0 0.62 993680.0 14838.4905660379 0.0849873422587367 0.4027 0.6449 2079975 MixCom4_000200 CS(=O)(=O)c1ccc(N2CCC(O)CC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J16 compound treatment 38790.0 -1100000.0 -5.38 27300.0 -1050000.0 -6.26 32840.0 -946001.509433962 -5.41821647570808 -9.8493 -0.9974 2080001 MixCom4_000201 CN(C)CCC(=O)c1ccc(cc1)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J17 compound treatment 1042440.0 -96800.0 -0.47 1094470.0 13700.0 0.08 867120.0 -111721.509433962 -0.639884098565834 -0.5955 -0.7446 2079976 MixCom4_000202 FC(F)(F)c1cccc(c1)C(=O)N2CCc3nc4ccccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J18 compound treatment 1101600.0 -37600.0 -0.18 1072340.0 -8450.0 -0.05 1037440.0 58598.4905660379 0.335622410609584 0.0586 0.1517 2079730 MixCom4_000203 O=C(C1CCN(Cc2ccccn2)CC1)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J19 compound treatment 1082440.0 -56800.0 -0.28 1053630.0 -27200.0 -0.16 963460.0 -15381.5094339621 -0.0880974787093299 -0.3043 -0.914 2079978 MixCom4_000204 O=C(N1CCc2nc3ccccn3c(=O)c2C1)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J20 compound treatment 896970.0 -242000.0 -1.18 931150.0 -150000.0 -0.89 708970.0 -269871.509433962 -1.54568702497549 -2.0896 -0.9762 2080004 MixCom4_000205 CCCN1CCC(CC1)N(C(=O)C2CC2)c3ccc4[nH]c(cc4c3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J21 compound treatment 989540.0 -150000.0 -0.73 991580.0 -89200.0 -0.53 837560.0 -141281.509433962 -0.809188774535921 -1.1958 -0.9858 2079980 MixCom4_000206 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)c4ccc(Cl)cc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J22 compound treatment 1287570.0 148000.0 0.72 1126350.0 45600.0 0.27 931720.0 -47121.5094339621 -0.26988808815759 0.419 0.5114 2079773 MixCom4_000207 Cc1ccccc1C(=O)N2CCC(CC2)N3CCN(CC3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J23 mock treatment 1340860.0 202000.0 0.99 1083550.0 2760.0 0.02 923740.0 -55101.5094339621 -0.315593477678609 0.396 0.3828 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 J24 mock treatment 1173320.0 34100.0 0.17 1153130.0 72300.0 0.43 937880.0 -40961.5094339621 -0.23460673484312 0.209 0.4039 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K01 compound treatment 1070940.0 -68300.0 -0.33 1141950.0 61200.0 0.36 1115380.0 136538.490566038 0.782023169916371 0.4688 0.5069 2075135 MixCom4_000208 COc1ccc(CC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K02 compound treatment 964380.0 -175000.0 -0.85 1110690.0 29900.0 0.18 893540.0 -85301.5094339621 -0.488563748798252 -0.6727 -0.6726 2079982 MixCom4_000209 CN(Cc1ccccc1)c2cc(nc(n2)c3ccccc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K03 compound treatment 1190600.0 51400.0 0.25 1105400.0 24600.0 0.15 980690.0 1848.49056603794 0.0105872157076055 0.2355 0.8101 2075136 MixCom4_000210 CN1CCN(CC1)c2ccc(CNC(=O)c3ccsc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K04 compound treatment 745070.0 -394000.0 -1.93 774690.0 -306000.0 -1.82 733140.0 -245701.509433962 -1.40725353315556 -2.9753 -0.9916 2079983 MixCom4_000211 Fc1ccc(cc1)c2cc(NCC=C)nc(n2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K05 compound treatment 1104640.0 -34600.0 -0.17 1013760.0 -67000.0 -0.4 920130.0 -58711.5094339621 -0.336269725319069 -0.5219 -0.952 2075137 MixCom4_000212 Fc1ccc(cc1)C2CCCN2C(=O)C3CCCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K06 compound treatment 601970.0 -537000.0 -2.63 738560.0 -342000.0 -2.04 979310.0 468.490566037945 0.00268327616637676 -2.689 -0.8096 2079984 MixCom4_000213 Fc1ccc(cc1)c2cc(nc(n2)c3ccncc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K07 compound treatment 1188710.0 49500.0 0.24 939000.0 -142000.0 -0.84 1002170.0 23328.4905660379 0.133613752914557 -0.2701 -0.3045 2075138 MixCom4_000214 CN1CCN(CC1)c2ccc(CNS(=O)(=O)Cc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K08 compound treatment 209050.0 -930000.0 -4.54 422000.0 -659000.0 -3.92 423150.0 -555691.509433962 -3.18271890879722 -6.7233 -0.9899 2079985 MixCom4_000215 Fc1ccc(cc1)c2cc(NC3CC3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K09 compound treatment 1149500.0 10300.0 0.05 1165400.0 84600.0 0.5 938560.0 -40281.5094339621 -0.230712039996718 0.1862 0.3351 2075139 MixCom4_000216 OC(CNCC1COc2ccccc2O1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K10 compound treatment 1267680.0 128000.0 0.63 1237220.0 156000.0 0.93 868060.0 -110781.509433962 -0.634500255689924 0.533 0.4135 2079986 MixCom4_000217 Cc1nc(cc(n1)c2ccccc2F)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K11 compound treatment 1562720.0 423000.0 2.07 1007380.0 -73400.0 -0.44 977020.0 -1821.50943396206 -0.010432681478126 0.9365 0.4429 2075140 MixCom4_000218 OC(CN1CCN=C(C=C1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K12 compound treatment 1098110.0 -41100.0 -0.2 911890.0 -169000.0 -1.0 798750.0 -180091.509433962 -1.03147275540193 -1.2914 -0.8884 2079987 MixCom4_000219 Cc1nc(NCc2ccco2)cc(n1)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K13 compound treatment 1158740.0 19500.0 0.1 1239480.0 159000.0 0.94 838490.0 -140351.509433962 -0.803862206584224 0.1357 0.1092 2075141 MixCom4_000220 COc1cc2CCN(Cc2cc1OC)C(=O)COc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K14 compound treatment 594490.0 -545000.0 -2.66 498730.0 -582000.0 -3.46 517990.0 -460851.509433962 -2.63952352757249 -5.0589 -0.9915 2079988 MixCom4_000221 Cc1cnc(CNc2cc(nc(n2)c3ccccc3)c4ccccc4F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K15 compound treatment 948820.0 -190000.0 -0.93 949690.0 -131000.0 -0.78 800850.0 -177991.509433962 -1.01944502131745 -1.5758 -0.9941 2075142 MixCom4_000222 CN1C/2CCC1/C(=C\c3ccc(F)cc3)/C(=O)\C2=C\c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K16 compound treatment 923240.0 -216000.0 -1.06 909980.0 -171000.0 -1.02 770970.0 -207871.509433962 -1.19058249486231 -1.8831 -0.9976 2079989 MixCom4_000223 CC(Nc1cc(nc(n1)c2ccccc2)c3ccccc3F)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K17 compound treatment 394850.0 -744000.0 -3.64 269060.0 -812000.0 -4.83 479960.0 -498881.509433962 -2.85734006434997 -6.5364 -0.9777 2075143 MixCom4_000224 OC(CNCc1ccc(cc1)C(F)(F)F)CO/N=C/C2=C(Cl)c3cc(Cl)ccc3OC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K18 compound treatment 417600.0 -722000.0 -3.53 511870.0 -569000.0 -3.38 691270.0 -287571.509433962 -1.64706364083038 -4.9398 -0.958 2079990 MixCom4_000225 OC1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K19 compound treatment 1059550.0 -79700.0 -0.39 972350.0 -108000.0 -0.64 943400.0 -35441.5094339621 -0.202990976678205 -0.7143 -0.9156 2075144 MixCom4_000226 CN(C)c1ccc(CC(C)(C)NC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K20 compound treatment 1003280.0 -136000.0 -0.66 974290.0 -106000.0 -0.63 888090.0 -90751.5094339621 -0.519778582493684 -1.0493 -0.9948 2079991 MixCom4_000227 CN(Cc1ccccc1)c2cc(nc(n2)c3ccncc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K21 compound treatment 1124160.0 -15100.0 -0.07 1130180.0 49400.0 0.29 1049550.0 70708.4905660379 0.404982343830076 0.3608 0.7136 2075145 MixCom4_000228 CCOC(=O)c1nc(C)sc1C(=O)/C=C/N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K22 compound treatment 967690.0 -172000.0 -0.84 1094640.0 13900.0 0.08 868410.0 -110431.509433962 -0.632495633342511 -0.8015 -0.761 2079992 MixCom4_000229 Cc1cnc(CNc2cc(nc(C)n2)c3cccc(c3)C(F)(F)F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K23 mock treatment 1256990.0 118000.0 0.58 1090940.0 10200.0 0.06 973760.0 -5081.50943396206 -0.0291043067711735 0.3502 0.6046 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 K24 mock treatment 1198150.0 58900.0 0.29 1243900.0 163000.0 0.97 969520.0 -9321.50943396206 -0.0533888746369777 0.6953 0.6863 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L01 compound treatment 802460.0 -337000.0 -1.65 851590.0 -229000.0 -1.36 769040.0 -209801.509433962 -1.20163655523519 -2.4307 -0.9916 2079993 MixCom4_000230 CN1CCN(CC1)c2cc(nc(C)n2)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L02 compound treatment 1326330.0 187000.0 0.91 1003100.0 -77700.0 -0.46 1057120.0 78278.4905660379 0.448339461458411 0.5199 0.465 1676216 MixCom4_000231 O=C(N1CCN(CC1)C2c3ccccc3-c4ccccc24)c5cccs5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L03 compound treatment 526640.0 -613000.0 -2.99 619620.0 -461000.0 -2.74 603530.0 -375311.509433962 -2.14959382586473 -4.5524 -0.9911 2079995 MixCom4_000232 FC(F)(F)c1cccc(c1)c2cc(NC3CC3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L04 compound treatment 1074520.0 -64700.0 -0.32 1125050.0 44300.0 0.26 1005160.0 26318.4905660379 0.150738955253886 0.0564 0.1287 2075101 MixCom4_000233 CC(C)(C)OC(=O)NC1CCNCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L05 compound treatment 1160380.0 21100.0 0.1 1216360.0 136000.0 0.81 1063450.0 84608.4905660379 0.484594488484482 0.8048 0.8505 2079997 MixCom4_000234 OC(=O)CC1(CC(=O)N2CCCC2)CCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L06 mock treatment 1171890.0 32600.0 0.16 1106750.0 26000.0 0.15 966020.0 -12821.5094339621 -0.0734350981111085 0.1388 0.5937 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L07 compound treatment 1490480.0 351000.0 1.72 1343870.0 263000.0 1.56 990880.0 12038.4905660379 0.0689503634794321 1.9338 0.8324 2079998 MixCom4_000235 CS(=O)(=O)c1ccc(N2CCOCC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L08 mock treatment 1388680.0 249000.0 1.22 1085250.0 4460.0 0.03 1135630.0 156788.490566038 0.898004891445271 1.2374 0.8173 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L09 compound treatment 1076660.0 -62600.0 -0.31 1290920.0 210000.0 1.25 1029870.0 51028.4905660379 0.292265292981249 0.7136 0.541 2079999 MixCom4_000236 CS(=O)(=O)c1ccc(NC2CCCCC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L10 mock treatment 1236000.0 96800.0 0.47 1066080.0 -14700.0 -0.09 956390.0 -22451.5094339621 -0.128590850127074 0.1482 0.2978 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L11 compound treatment 1525390.0 386000.0 1.89 1396440.0 316000.0 1.88 1082190.0 103348.490566038 0.591927696457399 2.5147 0.9224 2080000 MixCom4_000237 CS(=O)(=O)c1ccc(NCc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L12 compound treatment 1281080.0 142000.0 0.69 1260270.0 179000.0 1.07 885860.0 -92981.5094339621 -0.532550890592916 0.7088 0.5138 2080007 MixCom4_000238 Cc1ccccc1C(=O)N2CCc3nc4c(C)cccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L13 compound treatment 1337210.0 198000.0 0.97 1343310.0 263000.0 1.56 1190980.0 212138.490566038 1.2150215969576 2.1612 0.9815 2080002 MixCom4_000239 CS(=O)(=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L14 compound treatment 1033770.0 -105000.0 -0.52 1262770.0 182000.0 1.08 871780.0 -107061.509433962 -0.613193983883134 -0.0268 -0.0199 2080009 MixCom4_000240 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)Cc4cc(F)cc(F)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L15 compound treatment 1118830.0 -20400.0 -0.1 1119620.0 38800.0 0.23 1032830.0 53988.4905660379 0.309218670547943 0.2543 0.6379 2080003 MixCom4_000241 CS(=O)(=O)c1ccc(cc1)N2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L16 compound treatment 1060000.0 -79200.0 -0.39 1099290.0 18500.0 0.11 913920.0 -64921.5094339621 -0.371837453254599 -0.3747 -0.6838 2080022 MixCom4_000242 CN1CCC(CC1)Nc2ccc3N(CCc3c2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L17 compound treatment 1179090.0 39800.0 0.19 1118560.0 37800.0 0.22 963580.0 -15261.5094339621 -0.0874101796187883 0.1916 0.6184 2080005 MixCom4_000243 CC(C)(C)C(=O)N1CCc2nc3ccccn3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L18 compound treatment 1377600.0 238000.0 1.16 1362410.0 282000.0 1.67 999250.0 20408.4905660379 0.116889475044711 1.7067 0.8353 2080024 MixCom4_000244 COc1ccc(cc1)S(=O)(=O)N2CCCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L19 compound treatment 1423060.0 284000.0 1.39 1320580.0 240000.0 1.43 978300.0 -541.509433962055 -0.00310149117901527 1.6221 0.8155 2080006 MixCom4_000245 Fc1cccc(F)c1C(=O)N2CCc3nc4ccccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L20 compound treatment 47780.0 -1090000.0 -5.33 36560.0 -1040000.0 -6.21 35040.0 -943801.509433962 -5.40561599238148 -9.7849 -0.9975 2080029 MixCom4_000246 CCCN1CCC(CC1)N(C(=O)c2cccc(c2)C(F)(F)F)c3ccc4[nH]c(cc4c3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L21 compound treatment 1263410.0 124000.0 0.61 1015040.0 -65700.0 -0.39 943930.0 -34911.5094339621 -0.19995540569498 0.0091 0.0121 2080008 MixCom4_000247 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)Cc4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L22 compound treatment 1096720.0 -42500.0 -0.21 1010590.0 -70200.0 -0.42 943260.0 -35581.5094339621 -0.203792825617171 -0.4786 -0.9406 2079746 MixCom4_000248 Clc1cccc(CNC(=O)C2CCN(Cc3cccnc3)CC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L23 mock treatment 1147320.0 8070.0 0.04 1148040.0 67300.0 0.4 943170.0 -35671.5094339621 -0.204308299935077 0.1357 0.301 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 L24 mock treatment 1188510.0 49300.0 0.24 1074990.0 -5800.0 -0.03 1043040.0 64198.4905660379 0.367696368168193 0.3313 0.7517 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M01 compound treatment 1049170.0 -90100.0 -0.44 1012210.0 -68600.0 -0.41 1044450.0 65608.4905660379 0.375772132482057 -0.2726 -0.385 2075146 MixCom4_000249 COc1ccc(cc1)C(=O)NCc2ccc(cc2)N3CCN(C)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M02 compound treatment 51680.0 -1090000.0 -5.31 32740.0 -1050000.0 -6.23 44050.0 -934791.509433962 -5.35401128566665 -9.7572 -0.9972 2080010 MixCom4_000250 CN1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M03 compound treatment 947840.0 -191000.0 -0.94 1163520.0 82700.0 0.49 883580.0 -95261.5094339621 -0.545609573313207 -0.5709 -0.4801 2075147 MixCom4_000251 CN1CCN(CC1)c2ccc(CNC(=O)c3ccc(C)c(C)c3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M04 compound treatment 127040.0 -1010000.0 -4.95 156000.0 -925000.0 -5.5 141990.0 -836851.509433962 -4.79306067793626 -8.7976 -0.9982 2080011 MixCom4_000252 CN1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M05 compound treatment 1040590.0 -98700.0 -0.48 1290620.0 210000.0 1.25 1021770.0 42928.4905660379 0.245872604369689 0.5841 0.4294 2075148 MixCom4_000253 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M06 compound treatment 944040.0 -195000.0 -0.95 1082080.0 1290.0 0.01 702720.0 -276121.509433962 -1.58148385260786 -1.4593 -0.7902 2080012 MixCom4_000254 Fc1ccc(cc1)c2cc(nc(n2)c3ccncc3)N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M07 compound treatment 1153930.0 14700.0 0.07 926910.0 -154000.0 -0.92 881380.0 -97461.5094339621 -0.558210056639803 -0.8092 -0.7532 2075149 MixCom4_000255 CN1CCN(CC1)c2ccc(CNS(=O)(=O)Cc3ccc(Cl)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M08 compound treatment 1215370.0 76100.0 0.37 1012970.0 -67800.0 -0.4 943220.0 -35621.5094339621 -0.204021925314018 -0.1359 -0.2322 2080013 MixCom4_000256 CN(C)CCNc1cc(nc(C)n1)c2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M09 compound treatment 1469300.0 330000.0 1.61 1370770.0 290000.0 1.72 1074510.0 95668.4905660379 0.547940554662735 2.243 0.9254 2075150 MixCom4_000257 OC(CNCc1ccco1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M10 compound treatment 896740.0 -243000.0 -1.18 978320.0 -102000.0 -0.61 828540.0 -150301.509433962 -0.860850756174967 -1.5329 -0.9664 2080014 MixCom4_000258 Cc1nc(cc(n1)c2ccccc2F)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M11 compound treatment 1324520.0 185000.0 0.91 1387920.0 307000.0 1.83 966760.0 -12081.5094339621 -0.0691967537194352 1.5371 0.7537 1478188 MixCom4_000259 O=C(CN1C(=O)c2ccccc2C1=O)N3CCCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M12 compound treatment 1065850.0 -73400.0 -0.36 937920.0 -143000.0 -0.85 874260.0 -104581.509433962 -0.598989802678607 -1.0434 -0.9488 2080015 MixCom4_000260 Cc1nc(cc(n1)c2ccccc2F)N3CCc4ccccc4C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M13 compound treatment 1261940.0 123000.0 0.6 1308370.0 228000.0 1.35 931580.0 -47261.5094339621 -0.270689937096556 0.9712 0.6454 2075151 MixCom4_000261 COc1cc2CCN(Cc2cc1OC)C(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M14 compound treatment 902900.0 -236000.0 -1.15 850140.0 -231000.0 -1.37 850930.0 -127911.509433962 -0.732612200864741 -1.8815 -0.9714 2080016 MixCom4_000262 CCN(CC)c1cc(nc(n1)c2ccccc2)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M15 compound treatment 994470.0 -145000.0 -0.71 910080.0 -171000.0 -1.02 836270.0 -142571.509433962 -0.816577239759244 -1.4659 -0.9889 2075152 MixCom4_000263 O=C(COc1ccccc1)Nc2ccc3N4CCCC4COc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M16 compound treatment 314270.0 -825000.0 -4.03 367610.0 -713000.0 -4.24 629450.0 -349391.509433962 -2.00113722230774 -5.931 -0.9592 2080017 MixCom4_000264 CCN(CC)c1cc(nc(n1)c2cccnc2)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M17 compound treatment 324960.0 -814000.0 -3.98 321030.0 -760000.0 -4.52 350240.0 -628601.509433962 -3.60031038122547 -6.984 -0.9957 2075153 MixCom4_000265 OC(CO/N=C/C1=C(Cl)c2cc(Cl)ccc2OC1)CN3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M18 compound treatment 918880.0 -220000.0 -1.08 846240.0 -235000.0 -1.39 722190.0 -256651.509433962 -1.46996957516748 -2.2756 -0.9917 2080018 MixCom4_000266 Fc1ccccc1c2cc(NCc3ccccc3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M19 compound treatment 1131600.0 -7650.0 -0.04 1054160.0 -26600.0 -0.16 847600.0 -131241.509433962 -0.751684750627272 -0.547 -0.7112 1173337 MixCom4_000267 Clc1cccc(Cl)c1c2noc(CN3CCOCC3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M20 compound treatment 511200.0 -628000.0 -3.07 604110.0 -477000.0 -2.83 511200.0 -467641.509433962 -2.6784132011123 -4.9546 -0.9984 2080019 MixCom4_000268 Fc1ccccc1c2cc(NCC=C)nc(n2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M21 compound treatment 996820.0 -142000.0 -0.7 1001600.0 -79200.0 -0.47 862820.0 -116021.509433962 -0.664512315976909 -1.0573 -0.987 2075154 MixCom4_000269 CN(C)/C=C/C(=O)c1csc(n1)c2ccc(cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M22 compound treatment 1119040.0 -20200.0 -0.1 963260.0 -118000.0 -0.7 912640.0 -66201.5094339621 -0.379168643553709 -0.6794 -0.848 2080020 MixCom4_000270 Cc1nc(cc(n1)c2cccc(c2)C(F)(F)F)N3CCC4(CC3)OCCO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M23 mock treatment 1199630.0 60400.0 0.3 1180000.0 99200.0 0.59 929790.0 -49051.5094339621 -0.280942148530468 0.3487 0.4864 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 M24 mock treatment 1155900.0 16700.0 0.08 1010460.0 -70300.0 -0.42 1073650.0 94808.4905660379 0.54301491118052 0.119 0.1725 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N01 compound treatment 918400.0 -221000.0 -1.08 887010.0 -194000.0 -1.15 989820.0 10978.4905660379 0.062879221512981 -1.252 -0.7924 2080021 MixCom4_000271 Cc1nc(cc(n1)c2cccc(c2)C(F)(F)F)N3CCC(O)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N02 compound treatment 1193410.0 54200.0 0.26 1028610.0 -52200.0 -0.31 986770.0 7928.49056603794 0.0454103696283813 -1.0E-4 -3.0E-4 1188987 MixCom4_000272 CC(C)(C)C(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N03 compound treatment 770950.0 -368000.0 -1.8 772740.0 -308000.0 -1.83 786080.0 -192761.509433962 -1.10404008437828 -2.7339 -0.9781 2080023 MixCom4_000273 FC(F)(F)c1cccc(c1)c2cc(NC3CC3)nc(n2)c4ccncc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N04 compound treatment 1345290.0 206000.0 1.01 1288520.0 208000.0 1.24 994670.0 15828.4905660379 0.0906575597557051 1.3468 0.8438 1627910 MixCom4_000274 CN1CCN(CC1)c2ccc(NC(=O)c3ccccc3Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N05 compound treatment 1240370.0 101000.0 0.49 1282330.0 202000.0 1.2 1100890.0 122048.490566038 0.699031804733469 1.3808 0.9375 2080025 MixCom4_000275 OC(=O)CC1(CC(=O)N2CCc3ccccc3C2)CCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N06 mock treatment 1159930.0 20700.0 0.1 1154000.0 73200.0 0.44 1034560.0 55718.4905660379 0.319127232436585 0.4939 0.8994 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N07 compound treatment 1371900.0 233000.0 1.14 1307400.0 227000.0 1.35 1097860.0 119018.490566038 0.681677502697293 1.8279 0.967 2080026 MixCom4_000276 CS(=O)(=O)c1ccc(N2CCCCC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N08 mock treatment 1221720.0 82500.0 0.4 1104650.0 23900.0 0.14 1024980.0 46138.4905660379 0.264257855041678 0.4671 0.9299 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N09 compound treatment 1261300.0 122000.0 0.6 1351750.0 271000.0 1.61 1054300.0 75458.4905660379 0.432187932830682 1.5241 0.8603 2080027 MixCom4_000277 CC1CN(CC(C)O1)c2ccc(cc2F)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N10 mock treatment 1255880.0 117000.0 0.57 1301280.0 220000.0 1.31 978820.0 -21.5094339620555 -1.23195120001549E-4 1.0859 0.7596 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N11 compound treatment 1421440.0 282000.0 1.38 1186190.0 105000.0 0.63 1057950.0 79108.4905660379 0.45309328016799 1.4195 0.8979 2080028 MixCom4_000278 CS(=O)(=O)c1ccc(NCc2ccco2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N12 compound treatment 1360220.0 221000.0 1.08 1286010.0 205000.0 1.22 1020030.0 41188.4905660379 0.235906767556836 1.4641 0.8893 2080032 MixCom4_000279 CCC(=O)N1CCc2nc3c(C)cccn3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N13 compound treatment 1332970.0 194000.0 0.95 1317120.0 236000.0 1.41 1088700.0 109858.490566038 0.629213672119282 1.7211 0.9522 2080030 MixCom4_000280 CS(=O)(=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3c(F)cccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N14 compound treatment 1257070.0 118000.0 0.58 1289970.0 209000.0 1.24 945250.0 -33591.5094339621 -0.192395115699022 0.9395 0.6787 2080034 MixCom4_000281 CC(C)CC(=O)N1CCc2nc3cccc(C)n3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N15 compound treatment 1458790.0 320000.0 1.56 1230720.0 150000.0 0.89 1051310.0 72468.4905660379 0.415062730491354 1.6558 0.8974 2080031 MixCom4_000282 CS(=O)(=O)c1ccc(N2CCNCC2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N16 compound treatment 1251440.0 112000.0 0.55 1248900.0 168000.0 1.0 1019430.0 40588.4905660379 0.232470272104128 1.0279 0.8834 2080036 MixCom4_000283 CN1CCC(CC1)N(C(=O)C2CC2)c3ccc4N(CCc4c3)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N17 compound treatment 1251650.0 112000.0 0.55 1086960.0 6170.0 0.04 917980.0 -60861.5094339621 -0.348583834024607 0.137 0.2103 2080033 MixCom4_000284 Clc1ccc(C(=O)N2CCc3nc4ccccn4c(=O)c3C2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N18 compound treatment 1258130.0 119000.0 0.58 1273850.0 193000.0 1.15 1011850.0 33008.4905660379 0.189055879551582 1.1073 0.8515 2080038 MixCom4_000285 COc1cccc(OC)c1C(=O)N2CCCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N19 compound treatment 1201600.0 62400.0 0.3 1121050.0 40300.0 0.24 936750.0 -42091.5094339621 -0.241078801279054 0.1749 0.3833 2080035 MixCom4_000286 Clc1ccc(cc1)C(=O)N2CCc3nc4ccccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N20 compound treatment 1045390.0 -93900.0 -0.46 972640.0 -108000.0 -0.64 773850.0 -204991.509433962 -1.17408731668931 -1.3139 -0.9285 2080051 MixCom4_000287 CCCN1CCC(CC1)N(C2CC2)C(=O)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N21 compound treatment 1200490.0 61200.0 0.3 1153060.0 72300.0 0.43 977950.0 -891.509433962055 -0.00510611352642835 0.4179 0.798 2080037 MixCom4_000288 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)C4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N22 compound treatment 1093310.0 -45900.0 -0.22 1202490.0 122000.0 0.72 777240.0 -201601.509433962 -1.15467111738151 -0.3784 -0.274 2080053 MixCom4_000289 COc1ccc(cc1)c2cnc(NCCN(C)C)nc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N23 mock treatment 1444180.0 305000.0 1.49 1282650.0 202000.0 1.2 1029520.0 50678.4905660379 0.290260670633836 1.7208 0.8892 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 N24 mock treatment 1265310.0 126000.0 0.62 1112700.0 31900.0 0.19 980260.0 1418.49056603794 0.00812439396649798 0.4699 0.729 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O01 compound treatment 904340.0 -235000.0 -1.15 769060.0 -312000.0 -1.85 876000.0 -102841.509433962 -0.589023965865753 -2.0729 -0.9179 2075155 MixCom4_000290 CN1CCN(CC1)c2ccc(CNC(=O)c3csc4ccccc34)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O02 compound treatment 367530.0 -772000.0 -3.77 187840.0 -893000.0 -5.31 327380.0 -651461.509433962 -3.73124085797365 -7.3968 -0.9855 2080039 MixCom4_000291 OC1CCN(CC1)c2cc(nc(n2)c3ccccc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O03 compound treatment 1237930.0 98700.0 0.48 1232690.0 152000.0 0.9 1236880.0 258038.490566038 1.47791349908977 1.6532 0.9195 2075156 MixCom4_000292 OC(CN1CCC(CC1)C(=O)c2ccc(F)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O04 compound treatment 151470.0 -988000.0 -4.83 199520.0 -881000.0 -5.24 540390.0 -438451.509433962 -2.51122769733805 -7.2618 -0.9613 2080040 MixCom4_000293 OC1CCN(CC1)c2cc(nc(n2)c3cccnc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O05 compound treatment 1025760.0 -113000.0 -0.55 866400.0 -214000.0 -1.27 871540.0 -107301.509433962 -0.614568582064217 -1.411 -0.9283 2075157 MixCom4_000294 CN1CCN(CC1)c2ccc(CNS(=O)(=O)c3ccccc3C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O06 compound treatment 947200.0 -192000.0 -0.94 824450.0 -256000.0 -1.52 641990.0 -336851.509433962 -1.92931446734614 -2.5357 -0.9635 2080041 MixCom4_000295 CN(Cc1ccccc1)c2cc(nc(n2)c3ccncc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O07 compound treatment 1112290.0 -27000.0 -0.13 923580.0 -157000.0 -0.93 899600.0 -79241.5094339621 -0.4538551447259 -0.8778 -0.838 2075158 MixCom4_000296 CN1CCN(CC1)c2ccc(CNS(=O)(=O)Cc3cccc(c3)C(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O08 compound treatment 1083240.0 -56000.0 -0.27 1201550.0 121000.0 0.72 934250.0 -44591.5094339621 -0.255397532332005 0.1092 0.1348 2080042 MixCom4_000297 Cc1nc(NCCC#N)cc(n1)c2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O09 compound treatment 1383220.0 244000.0 1.19 1239950.0 159000.0 0.95 1074560.0 95718.4905660379 0.548226929283794 1.5512 0.9588 2075159 MixCom4_000298 Cn1cccc1CNCC(O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O10 compound treatment 967540.0 -172000.0 -0.84 786430.0 -294000.0 -1.75 840480.0 -138361.509433962 -0.792464496666075 -1.9525 -0.9313 2080043 MixCom4_000299 CN(Cc1ccccc1)c2cc(nc(C)n2)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O11 compound treatment 1424410.0 285000.0 1.39 1207480.0 127000.0 0.75 1027700.0 48858.4905660379 0.279836634427288 1.4009 0.871 1677557 MixCom4_000300 CC1CCN(CC1)C(=O)CN2C(=O)c3ccccc3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O12 compound treatment 1051680.0 -87600.0 -0.43 969120.0 -112000.0 -0.66 956370.0 -22471.5094339621 -0.128705399975498 -0.7047 -0.8805 2080044 MixCom4_000301 Cc1nc(NCCc2ccccc2)cc(n1)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O13 compound treatment 1115260.0 -24000.0 -0.12 1271320.0 191000.0 1.13 964330.0 -14511.5094339621 -0.0831145603029031 0.5385 0.4715 2075160 MixCom4_000302 COc1cc2CCN(Cc2cc1OC)C(=O)C3CCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O14 compound treatment 982950.0 -156000.0 -0.76 895570.0 -185000.0 -1.1 898840.0 -80001.5094339621 -0.458208038965997 -1.3413 -0.947 2080045 MixCom4_000303 Fc1ccccc1c2cc(nc(n2)c3ccccc3)N4CCOCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O15 compound treatment 1087730.0 -51500.0 -0.25 917190.0 -164000.0 -0.97 929520.0 -49321.5094339621 -0.282488571484187 -0.8701 -0.8335 2075161 MixCom4_000304 Cc1ccc(F)cc1S(=O)(=O)Nc2ccc3N4CCCC4COc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O16 compound treatment 798730.0 -341000.0 -1.66 741320.0 -339000.0 -2.02 690830.0 -288011.509433962 -1.6495837374957 -3.0784 -0.9954 2080046 MixCom4_000305 Fc1ccccc1c2cc(NCc3ccncc3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O17 compound treatment 832130.0 -307000.0 -1.5 677460.0 -403000.0 -2.4 637960.0 -340881.509433962 -1.9523962618035 -3.3783 -0.9828 2075162 MixCom4_000306 OC(CNCc1ccc(F)cc1)CO/N=C/C2=C(Cl)c3cc(Cl)ccc3OC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O18 compound treatment 912520.0 -227000.0 -1.11 860820.0 -220000.0 -1.31 756420.0 -222421.509433962 -1.27391750959049 -2.1303 -0.9975 2080047 MixCom4_000307 Fc1ccccc1c2cc(NCc3ccco3)nc(n2)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O19 compound treatment 1195640.0 56400.0 0.28 946250.0 -135000.0 -0.8 848410.0 -130431.509433962 -0.747045481766116 -0.7341 -0.6504 1606129 MixCom4_000308 Clc1cccc(Cl)c1c2noc(CN3CCCCC3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O20 compound treatment 76320.0 -1060000.0 -5.19 81120.0 -1000000.0 -5.94 181120.0 -797721.509433962 -4.56894389949547 -9.0683 -0.9943 2080048 MixCom4_000309 CN1CCN(CC1)c2cc(nc(n2)c3ccncc3)c4ccccc4F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O21 compound treatment 978370.0 -161000.0 -0.79 815860.0 -265000.0 -1.58 765120.0 -213721.509433962 -1.22408832552622 -2.0701 -0.9654 2075163 MixCom4_000310 CN(C)/C=C/C(=O)c1cc(no1)c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O22 compound treatment 799240.0 -340000.0 -1.66 873720.0 -207000.0 -1.23 857960.0 -120881.509433962 -0.692347929143844 -2.0697 -0.9491 2080049 MixCom4_000311 CCN(CC)c1cc(nc(C)n1)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O23 mock treatment 1311600.0 172000.0 0.84 1201500.0 121000.0 0.72 1098630.0 119788.490566038 0.686087671861602 1.2967 0.996 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 O24 mock treatment 1105440.0 -33800.0 -0.17 964590.0 -116000.0 -0.69 879280.0 -99561.5094339621 -0.570237790724282 -0.8235 -0.904 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P01 compound treatment 785780.0 -353000.0 -1.73 781370.0 -299000.0 -1.78 832710.0 -146131.509433962 -0.836967112778645 -2.5083 -0.9581 2080050 MixCom4_000312 Cc1nc(NCc2ccccc2)cc(n1)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P02 compound treatment 1228890.0 89600.0 0.44 1157050.0 76300.0 0.45 1105460.0 126618.490566038 0.725206445098263 0.9334 0.9713 2075102 MixCom4_000313 NC(=O)C1=CN(Cc2ccc(Cl)cc2)CCC1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P03 compound treatment 848170.0 -291000.0 -1.42 825080.0 -256000.0 -1.52 829150.0 -149691.509433962 -0.857356985798047 -2.194 -0.9744 2080052 MixCom4_000314 COc1ccc(cc1)c2cnc(nc2)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P04 compound treatment 1103210.0 -36000.0 -0.18 1125760.0 45000.0 0.27 1112640.0 133798.490566038 0.766329840682337 0.4952 0.5962 1443609 MixCom4_000315 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P05 compound treatment 1335300.0 196000.0 0.96 1104540.0 23800.0 0.14 1080600.0 101758.490566038 0.582820983507722 0.9711 0.8593 2080054 MixCom4_000316 Fc1ccc(CC(=O)N2CCNC(=O)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P06 mock treatment 1289600.0 150000.0 0.73 1105570.0 24800.0 0.15 1150790.0 171948.490566038 0.984833676550363 1.0778 0.871 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P07 compound treatment 1232820.0 93600.0 0.46 1172160.0 91400.0 0.54 1046080.0 67238.4905660379 0.385107945128581 0.8 0.9903 2080055 MixCom4_000317 CN1CCN(CC1)c2ccc(cc2F)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P08 mock treatment 72260.0 -1070000.0 -5.21 1065610.0 -15200.0 -0.09 1049760.0 70918.4905660379 0.406185117238524 -2.8274 -0.5406 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P09 compound treatment 1303880.0 165000.0 0.8 1147640.0 66900.0 0.4 1107000.0 128158.490566038 0.734026783426881 1.1177 0.9642 2080056 MixCom4_000318 CN(C)CCNc1ccc(cc1)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P10 compound treatment 1193720.0 54500.0 0.27 1094210.0 13400.0 0.08 983460.0 4618.49056603794 0.0264523697142747 0.215 0.7703 2080057 MixCom4_000319 CC(C)CC(=O)N1CCc2nc3c(C)cccn3c(=O)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P11 compound treatment 525130.0 -614000.0 -3.0 294030.0 -787000.0 -4.68 569760.0 -409081.509433962 -2.34301124492799 -5.7862 -0.9593 2080058 MixCom4_000320 CS(=O)(=O)c1ccc(cc1)N2CCc3ccccc3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P12 compound treatment 1042080.0 -97200.0 -0.47 1237840.0 157000.0 0.93 961080.0 -17761.5094339621 -0.101728910671739 0.2064 0.1961 2080059 MixCom4_000321 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)c4cccc(c4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P13 compound treatment 1231540.0 92300.0 0.45 1100000.0 19200.0 0.11 1119650.0 140808.490566038 0.806479562554811 0.7919 0.8506 2080060 MixCom4_000322 CS(=O)(=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P14 compound treatment 848440.0 -291000.0 -1.42 770320.0 -310000.0 -1.85 817220.0 -161621.509433962 -0.925685970382727 -2.4207 -0.9656 2080061 MixCom4_000323 Cc1cccc2nc3CCN(Cc3c(=O)n12)C(=O)c4ccc(cc4)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P15 compound treatment 1183420.0 44200.0 0.22 1230650.0 150000.0 0.89 1043530.0 64688.4905660379 0.370502839454571 0.853 0.8626 2080062 MixCom4_000324 CC(=O)N1CCCN(CC1)c2ccc(cc2)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P16 compound treatment 1119400.0 -19800.0 -0.1 928700.0 -152000.0 -0.9 959140.0 -19701.5094339621 -0.112840245968829 -0.6433 -0.7018 2080063 MixCom4_000325 CN1CCC(CC1)N(C(=O)c2ccc(cc2)C(F)(F)F)c3ccc4N(CCc4c3)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P17 compound treatment 1153820.0 14600.0 0.07 1166120.0 85300.0 0.51 1001550.0 22708.4905660379 0.130062707613425 0.4092 0.774 2080064 MixCom4_000326 O=C(Cc1ccccc1)N2CCc3nc4ccccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P18 compound treatment 184740.0 -955000.0 -4.66 142970.0 -938000.0 -5.58 103300.0 -875541.509433962 -5.01465735971172 -8.8075 -0.9973 2080065 MixCom4_000327 COc1cccc(OC)c1CN2CCC(CC2)NCCc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P19 compound treatment 1144200.0 4950.0 0.02 1133540.0 52800.0 0.31 19580.0 -959261.509433962 -5.49416302521293 -2.977 -0.541 2080066 MixCom4_000328 Cc1ccccc1C(=O)N2CCc3nc4ccccn4c(=O)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P20 compound treatment 1232650.0 93400.0 0.46 1139380.0 58600.0 0.35 1093790.0 114948.490566038 0.65836660854309 0.8447 0.967 2080067 MixCom4_000329 O=C(NCCN1CCOCC1)c2cccc3cc[nH]c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P21 compound treatment 1231050.0 91800.0 0.45 1122690.0 41900.0 0.25 1058450.0 79608.4905660379 0.45595702637858 0.6661 0.9704 2080068 MixCom4_000330 Cc1cccn2c(=O)c3CN(CCc3nc12)C(=O)Cc4cc(F)cc(F)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P22 compound treatment 864160.0 -275000.0 -1.34 882960.0 -198000.0 -1.18 867560.0 -111281.509433962 -0.637364001900514 -1.8231 -0.9613 2080069 MixCom4_000331 CN1CCN(CC1)c2nc3ccccc3n4ccnc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P23 mock treatment 1187910.0 48700.0 0.24 1021650.0 -59100.0 -0.35 1070900.0 92058.4905660379 0.527264307022274 0.2387 0.3526 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.1306 P24 mock treatment 1083970.0 -55300.0 -0.27 937120.0 -144000.0 -0.85 855120.0 -123721.509433962 -0.708614007619996 -1.0583 -0.9264 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A01 mock treatment 857870.0 -249000.0 -1.22 751630.0 -178000.0 -1.06 839250.0 -174479.6875 -0.999331087806145 -1.8914 -0.9964 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A02 mock treatment 914910.0 -192000.0 -0.94 852160.0 -77400.0 -0.46 933050.0 -80679.6875 -0.46209229869944 -1.0752 -0.9399 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A03 compound treatment 921330.0 -186000.0 -0.91 847040.0 -82500.0 -0.49 900670.0 -113059.6875 -0.647548503297255 -1.1817 -0.9696 678 NINDS_000001 NCC(CC(=O)O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A04 compound treatment 944920.0 -162000.0 -0.79 878990.0 -50600.0 -0.3 929310.0 -84419.6875 -0.483513120354654 -0.9108 -0.9328 679 NINDS_000002 CC(=O)Nc1cc(ccc1O)[As](=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A05 compound treatment 985510.0 -122000.0 -0.59 903680.0 -25900.0 -0.15 860450.0 -153279.6875 -0.877908248477124 -0.9392 -0.8765 3173079 NINDS_000003 CC1(C)N[C@@H](C(=O)N1C2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A06 compound treatment 967040.0 -140000.0 -0.69 864320.0 -65300.0 -0.39 891430.0 -122299.6875 -0.700470533268961 -1.024 -0.9717 1587004 NINDS_000004 COc1ccc(cc1)C2Sc3ccccc3N(CCN(C)C)C(=O)C2OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A07 compound treatment 763650.0 -344000.0 -1.68 638400.0 -291000.0 -1.73 626450.0 -387279.6875 -2.2181414750333 -3.2496 -0.9917 681 NINDS_000005 CC(CN1c2ccccc2Sc3ccccc13)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A08 compound treatment 998440.0 -109000.0 -0.53 948320.0 18700.0 0.11 992840.0 -20889.6875 -0.119645526837073 -0.3117 -0.5604 682 NINDS_000006 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3C(=O)C[C@@]21C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A09 compound treatment 914630.0 -193000.0 -0.94 937920.0 8340.0 0.05 940210.0 -73519.6875 -0.421083452963789 -0.7579 -0.7342 683 NINDS_000007 Cc1ncc([N+](=O)[O-])n1CCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A10 compound treatment 819290.0 -288000.0 -1.41 817920.0 -112000.0 -0.66 740480.0 -273249.6875 -1.56503551424612 -2.0992 -0.9513 3173081 NINDS_000008 COCCc1ccc(OCC(O)CNC(C)C)cc1.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A11 compound treatment 762850.0 -344000.0 -1.68 732500.0 -197000.0 -1.17 776250.0 -237479.6875 -1.3601631103405 -2.4334 -0.9889 684 NINDS_000009 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3OC(=O)CC)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A12 compound treatment 772960.0 -334000.0 -1.63 807810.0 -122000.0 -0.72 785670.0 -228059.6875 -1.30621013173298 -2.1152 -0.9557 3044526 NINDS_000010 NC(=N)N/N=C\c1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A13 compound treatment 994910.0 -112000.0 -0.55 953540.0 24000.0 0.14 956750.0 -56979.6875 -0.326350728317468 -0.4231 -0.6466 686 NINDS_000011 C(Nc1ncnc2[nH]cnc12)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A14 compound treatment 694410.0 -413000.0 -2.02 688960.0 -241000.0 -1.43 668800.0 -344929.6875 -1.97558217099632 -3.1313 -0.9893 687 NINDS_000012 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A15 compound treatment 706270.0 -401000.0 -1.96 765600.0 -164000.0 -0.98 680400.0 -333329.6875 -1.90914325891063 -2.7963 -0.9629 3173083 NINDS_000013 CO[C@H]1[C@H](O)CC(=O)O[C@@H](C)C/C=C/C=C/[C@H](O[C@H]2CC[C@@H]([C@@H](C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1O[C@@H]3O[C@H](C)[C@@H](O[C@H]4C[C@@](C)(O)[C@H](O)[C@H](C)O4)[C@@H]([C@H]3O)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A16 compound treatment 961210.0 -146000.0 -0.71 923280.0 -6300.0 -0.04 898040.0 -115689.6875 -0.662611808364959 -0.8162 -0.8375 689 NINDS_000014 Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C(=O)O)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A17 compound treatment 849880.0 -257000.0 -1.26 832570.0 -97000.0 -0.58 866600.0 -147129.6875 -0.842684170086866 -1.5456 -0.9541 690 NINDS_000015 CC(C)NCC(O)COc1ccccc1CC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A18 compound treatment 942690.0 -165000.0 -0.8 930720.0 1140.0 0.01 965070.0 -48659.6875 -0.278697991373248 -0.6212 -0.73 691 NINDS_000016 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCNC3=O)c4ccccc4)C(=O)N2C1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A19 compound treatment 950790.0 -156000.0 -0.76 934920.0 5340.0 0.03 865670.0 -148059.6875 -0.848010738038564 -0.9126 -0.7991 692 NINDS_000017 CC(=O)Nc1nnc(s1)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A20 compound treatment 429310.0 -678000.0 -3.31 219330.0 -710000.0 -4.22 367060.0 -646669.6875 -3.70379573416324 -6.4892 -0.9951 693 NINDS_000018 CCN(CC)CCOc1ccc-2c(c1)C(=O)c3cc(OCCN(CC)CC)ccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A21 compound treatment 831520.0 -276000.0 -1.35 747480.0 -182000.0 -1.08 783710.0 -230019.6875 -1.3174360168785 -2.1636 -0.9956 694 NINDS_000019 C[C@H]1CC2C3CC[C@](O)(C(=O)C)[C@@]3(C)C[C@H](O)[C@]2(F)C4(C)C=CC(=O)C=C14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A22 compound treatment 861880.0 -245000.0 -1.2 839870.0 -89700.0 -0.53 799840.0 -213889.6875 -1.22505156412486 -1.7075 -0.9511 695 NINDS_000020 CC1CCC(CC1)NC(=O)N(CCCl)N=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A23 mock treatment 859590.0 -248000.0 -1.21 914800.0 -14800.0 -0.09 928960.0 -84769.6875 -0.485517742702067 -1.0297 -0.788 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 A24 mock treatment 829500.0 -278000.0 -1.36 885020.0 -44600.0 -0.27 899290.0 -114439.6875 -0.655452442838484 -1.3149 -0.8593 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B01 mock treatment 1059330.0 -47900.0 -0.23 964230.0 34600.0 0.21 938370.0 -75359.6875 -0.431622039018761 -0.2654 -0.4985 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B02 mock treatment 1015400.0 -91900.0 -0.45 833970.0 -95600.0 -0.57 973220.0 -40509.6875 -0.23201892814063 -0.7213 -0.9484 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B03 compound treatment 923790.0 -183000.0 -0.9 809060.0 -121000.0 -0.72 956900.0 -56829.6875 -0.325491604454291 -1.1192 -0.9382 696 NINDS_000021 Oc1cccc2Cc3cccc(O)c3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B04 compound treatment 1037800.0 -69500.0 -0.34 853240.0 -76300.0 -0.45 1006120.0 -7609.6875 -0.0435844274837999 -0.4832 -0.85 697 NINDS_000022 Cn1c(=O)n(C)c2ncn(CC(O)CO)c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B05 compound treatment 850560.0 -257000.0 -1.25 826270.0 -103000.0 -0.61 756920.0 -256809.6875 -1.47087553884191 -1.928 -0.9506 351 NINDS_000023 CC(C)NCC(O)COc1cccc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B06 compound treatment 1059360.0 -47900.0 -0.23 847250.0 -82300.0 -0.49 1020080.0 6350.3125 0.0363713667158761 -0.3968 -0.7295 698 NINDS_000024 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B07 compound treatment 1006430.0 -101000.0 -0.49 903200.0 -26400.0 -0.16 972850.0 -40879.6875 -0.234138100336466 -0.5102 -0.8989 699 NINDS_000025 OC(=O)CCC(=O)c1ccc(cc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B08 compound treatment 949090.0 -158000.0 -0.77 865060.0 -64500.0 -0.38 886750.0 -126979.6875 -0.727275197800084 -1.0876 -0.9638 700 NINDS_000026 CN1C2CC[C@H]1C[C@H](C2)OC(=O)C(O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B09 compound treatment 936870.0 -170000.0 -0.83 900160.0 -29400.0 -0.17 894350.0 -119379.6875 -0.683746255399114 -0.9764 -0.8946 701 NINDS_000027 Nc1c(Br)cc(Br)cc1CNC2CCC(O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B10 compound treatment 997980.0 -109000.0 -0.53 941610.0 12000.0 0.07 993860.0 -19869.6875 -0.11380348456747 -0.3327 -0.6042 702 NINDS_000028 CCCCCC(=O)O[C@@]1(CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B11 compound treatment 446440.0 -661000.0 -3.23 464480.0 -465000.0 -2.77 431600.0 -582129.6875 -3.33414337330027 -5.3858 -0.9969 3104621 NINDS_000029 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B12 compound treatment 931360.0 -176000.0 -0.86 937760.0 8180.0 0.05 895900.0 -117829.6875 -0.674868642146285 -0.8577 -0.7842 703 NINDS_000030 OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B13 compound treatment 30030.0 -1080000.0 -5.26 40110.0 -889000.0 -5.29 29870.0 -983859.6875 -5.635048903661 -9.3459 -0.9995 704 NINDS_000031 CN(C)c1ccc(cc1)C(=C2C=CC(=[N+](C)C)C=C2)c3ccc(cc3)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B14 compound treatment 912990.0 -194000.0 -0.95 848640.0 -80900.0 -0.48 925860.0 -87869.6875 -0.503272969207725 -1.1165 -0.9484 3044607 NINDS_000032 Oc1cc2C(=O)Cc3c(O)c(O)cc4c(=O)oc(c1O)c2c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B15 compound treatment 727090.0 -380000.0 -1.86 666630.0 -263000.0 -1.56 700370.0 -313359.6875 -1.79476523525966 -3.0114 -0.9974 705 NINDS_000033 CC(Cc1cccc(c1)C(F)(F)F)NCCOC(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B16 compound treatment 968170.0 -139000.0 -0.68 911640.0 -17900.0 -0.11 987840.0 -25889.6875 -0.148282988942975 -0.5395 -0.7668 404 NINDS_000034 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B17 compound treatment 1038620.0 -68600.0 -0.34 920640.0 -8940.0 -0.05 982100.0 -31629.6875 -0.181158795440549 -0.3289 -0.8547 706 NINDS_000035 Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B18 compound treatment 1002650.0 -105000.0 -0.51 894990.0 -34600.0 -0.21 916040.0 -97689.6875 -0.559516944783715 -0.7369 -0.9384 707 NINDS_000036 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CCC6C5CC[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B19 compound treatment 516810.0 -590000.0 -2.88 529760.0 -400000.0 -2.38 517620.0 -496109.6875 -2.84146447523034 -4.6788 -0.9964 2080198 NINDS_000037 CC(=O)C1=C(O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B20 compound treatment 986640.0 -121000.0 -0.59 843650.0 -85900.0 -0.51 954110.0 -59619.6875 -0.341471308309384 -0.8324 -0.9776 708 NINDS_000038 C1CNCCN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B21 compound treatment 45400.0 -1060000.0 -5.19 66280.0 -863000.0 -5.13 53020.0 -960709.6875 -5.50245745411068 -9.1361 -0.9995 709 NINDS_000039 COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B22 compound treatment 949600.0 -158000.0 -0.77 910470.0 -19100.0 -0.11 885140.0 -128589.6875 -0.736496460598184 -0.9356 -0.8729 710 NINDS_000040 CC(=O)OCC1=C(N2C(SC1)[C@H](NC(=O)CCCC(N)C(=O)O)C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B23 mock treatment 1022510.0 -84700.0 -0.41 946760.0 17200.0 0.1 995930.0 -17799.6875 -0.101947575255627 -0.2389 -0.5449 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 B24 mock treatment 1074990.0 -32300.0 -0.16 947210.0 17600.0 0.1 924680.0 -89049.6875 -0.510031410264718 -0.325 -0.5973 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C01 mock treatment 991910.0 -115000.0 -0.56 916670.0 -12900.0 -0.08 929390.0 -84339.6875 -0.483054920960959 -0.6486 -0.8692 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C02 mock treatment 1098950.0 -8300.0 -0.04 888520.0 -41100.0 -0.24 1022560.0 8830.3125 0.0505755479204031 -0.1352 -0.5351 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C03 compound treatment 992900.0 -114000.0 -0.56 944670.0 15100.0 0.09 1033040.0 19310.3125 0.110599668494372 -0.2069 -0.3589 711 NINDS_000041 Oc1cccc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C04 compound treatment 1073240.0 -34000.0 -0.17 1000530.0 70900.0 0.42 1015900.0 2170.3125 0.0124304483953427 0.1548 0.3413 712 NINDS_000042 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSc3ccncc3)C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C05 compound treatment 650730.0 -457000.0 -2.23 647750.0 -282000.0 -1.68 584600.0 -429129.6875 -2.45783703285969 -3.6744 -0.9882 43 NINDS_000043 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C06 compound treatment 998580.0 -109000.0 -0.53 925730.0 -3850.0 -0.02 1000870.0 -12859.6875 -0.0736537626949962 -0.3623 -0.6753 3173091 NINDS_000044 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)C(O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3OC4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C07 compound treatment 794600.0 -313000.0 -1.53 744960.0 -185000.0 -1.1 738770.0 -274959.6875 -1.57482952628634 -2.425 -0.9885 714 NINDS_000045 CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C(C)Cc2ccc(OC)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C08 compound treatment 993870.0 -113000.0 -0.55 904180.0 -25400.0 -0.15 929530.0 -84199.6875 -0.482253072021994 -0.6855 -0.9142 715 NINDS_000046 COc1c2ccoc2c(OC)c3oc(C)cc(=O)c13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C09 compound treatment 736380.0 -371000.0 -1.81 673610.0 -256000.0 -1.52 661670.0 -352059.6875 -2.01641919195933 -3.0892 -0.9936 716 NINDS_000047 CN(C)CCC=C1c2ccccc2C=Cc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C10 compound treatment 1062400.0 -44900.0 -0.22 929850.0 265.0 0.0 1009250.0 -4479.6875 -0.0256573762055058 -0.1404 -0.6364 717 NINDS_000048 OC(=O)c1ccccc1OP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C11 compound treatment 904420.0 -203000.0 -0.99 984720.0 55100.0 0.33 958400.0 -55329.6875 -0.316900365822521 -0.5658 -0.5187 3173092 NINDS_000049 CN(C)CCOC(c1ccccc1)c2ccccc2.Cn1c(=O)n(C)c2nc(Cl)[nH]c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C12 compound treatment 215810.0 -891000.0 -4.36 235320.0 -694000.0 -4.13 220520.0 -793209.6875 -4.54310247356299 -7.5212 -0.9992 2080598 NINDS_000050 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@H](O)CC2CC(=O)NC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C13 compound treatment 1237860.0 131000.0 0.64 898040.0 -31500.0 -0.19 998440.0 -15289.6875 -0.0875715692784641 0.2096 0.3124 370 NINDS_000051 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C14 compound treatment 1026400.0 -80900.0 -0.4 947910.0 18300.0 0.11 948030.0 -65699.6875 -0.37629446223016 -0.3824 -0.6874 718 NINDS_000052 Cn1c(=O)n(C)c2ncn(CCO)c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C15 compound treatment 1052380.0 -54900.0 -0.27 894560.0 -35000.0 -0.21 972640.0 -41089.6875 -0.235340873744914 -0.4109 -0.9947 719 NINDS_000053 CN(CC#C)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C16 compound treatment 606650.0 -501000.0 -2.45 563880.0 -366000.0 -2.17 617310.0 -396419.6875 -2.27049075576289 -3.9785 -0.9988 720 NINDS_000054 Fc1c[nH]c(=O)[nH]c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C17 compound treatment 1062110.0 -45100.0 -0.22 966650.0 37100.0 0.22 980580.0 -33149.6875 -0.189864583920743 -0.1097 -0.3005 721 NINDS_000055 CO[C@H]1C[C@H](O[C@H]2[C@H](C)[C@@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@@H](C)C[C@]4(CO4)C(=O)[C@H](C)[C@@H](O)[C@@H](C)[C@@H](C)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C18 compound treatment 1001600.0 -106000.0 -0.52 1020730.0 91100.0 0.54 939540.0 -74189.6875 -0.42492087288598 -0.2304 -0.2677 722 NINDS_000056 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C19 compound treatment 1035870.0 -71400.0 -0.35 935740.0 6160.0 0.04 963570.0 -50159.6875 -0.287289230005019 -0.3461 -0.7634 723 NINDS_000057 CC(C)NCC(O)COc1ccc(CC(=O)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C20 compound treatment 1031240.0 -76000.0 -0.37 889030.0 -40600.0 -0.24 972520.0 -41209.6875 -0.236028172835456 -0.4899 -0.9764 724 NINDS_000058 CCn1cc(C(=O)O)c(=O)c2ccc(C)nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C21 compound treatment 1027880.0 -79400.0 -0.39 887640.0 -41900.0 -0.25 950820.0 -62909.6875 -0.360314758375067 -0.5759 -0.9842 725 NINDS_000059 CC(=C)[C@@H]1CCC(=CC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C22 compound treatment 1063920.0 -43300.0 -0.21 927680.0 -1900.0 -0.01 1097060.0 83330.3125 0.47727373329833 0.1468 0.2811 726 NINDS_000060 CCOC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C23 mock treatment 1061150.0 -46100.0 -0.23 885720.0 -43900.0 -0.26 1003740.0 -9989.6875 -0.0572158594462089 -0.3137 -0.8979 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 C24 mock treatment 886160.0 -221000.0 -1.08 862400.0 -67200.0 -0.4 922190.0 -91539.6875 -0.524292866393457 -1.157 -0.9143 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D01 mock treatment 1114450.0 7200.0 0.04 873940.0 -55600.0 -0.33 928800.0 -84929.6875 -0.486434141489456 -0.4516 -0.7662 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D02 mock treatment 1071200.0 -36100.0 -0.18 882400.0 -47200.0 -0.28 1096450.0 82720.3125 0.47377996292141 0.0098 0.017 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D03 compound treatment 802240.0 -305000.0 -1.49 656800.0 -273000.0 -1.62 725760.0 -287969.6875 -1.64934420268589 -2.7492 -0.999 727 NINDS_000061 CCN(CC)C(C)CN1c2ccccc2Sc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D04 compound treatment 1182050.0 74800.0 0.37 892680.0 -36900.0 -0.22 905290.0 -108439.6875 -0.621087488311403 -0.2743 -0.3641 3273 NINDS_000062 NNCCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D05 compound treatment 1055630.0 -51600.0 -0.25 871390.0 -58200.0 -0.35 1003640.0 -10089.6875 -0.0577886086883269 -0.3788 -0.8766 728 NINDS_000063 Cc1cc(nnc1NCCN2CCOCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D06 compound treatment 941850.0 -165000.0 -0.81 853820.0 -75800.0 -0.45 1090900.0 77170.3125 0.44199237998386 -0.4715 -0.4598 729 NINDS_000064 OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D07 compound treatment 1002210.0 -105000.0 -0.51 1094780.0 165000.0 0.98 1011140.0 -2589.6875 -0.0148324155294752 0.2623 0.2366 3173210 NINDS_000065 CO/N=C(\C(=O)NC1[C@H]2SCC(=C(N2C1=O)C(=O)O)CSc3nc(=O)c(=O)[nH]n3C)/c4csc(N)n4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D08 compound treatment 45810.0 -1060000.0 -5.19 69850.0 -860000.0 -5.11 57300.0 -956429.6875 -5.47794378654803 -9.1085 -0.9995 731 NINDS_000066 CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D09 compound treatment 838880.0 -268000.0 -1.31 761660.0 -168000.0 -1.0 753120.0 -260609.6875 -1.4926400100424 -2.1953 -0.9873 732 NINDS_000067 Oc1cc(cc([N+](=O)[O-])c1O)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D10 compound treatment 674200.0 -433000.0 -2.12 607760.0 -322000.0 -1.91 665610.0 -348119.6875 -1.99385287181988 -3.4776 -0.9991 733 NINDS_000068 CC1(CC2CC3(C)C1)CC(N)(C2)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D11 compound treatment 1082730.0 -24500.0 -0.12 884500.0 -45100.0 -0.27 990180.0 -23549.6875 -0.134880656677413 -0.3018 -0.934 734 NINDS_000069 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D12 compound treatment 1033820.0 -73400.0 -0.36 1050270.0 121000.0 0.72 1037800.0 24070.3125 0.13786253241919 0.2868 0.3523 735 NINDS_000070 NNC(=O)c1ccncc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D13 compound treatment 1401370.0 294000.0 1.44 1081310.0 152000.0 0.9 1080770.0 67040.3125 0.383972881757304 1.5723 0.9038 736 NINDS_000071 COC(=O)C(N)CS 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D14 compound treatment 977470.0 -130000.0 -0.63 852500.0 -77100.0 -0.46 934010.0 -79719.6875 -0.456593905975107 -0.8944 -0.9872 737 NINDS_000072 c1nc(cs1)c2nc3ccccc3[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D15 compound treatment 993180.0 -114000.0 -0.56 931740.0 2160.0 0.01 1062280.0 48550.3125 0.278071546889682 -0.1538 -0.2469 738 NINDS_000073 CC(=O)Nc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D16 compound treatment 951620.0 -156000.0 -0.76 781440.0 -148000.0 -0.88 841010.0 -172719.6875 -0.989250701144868 -1.5188 -0.9944 1000104 NINDS_000074 Cc1c(CCC(=O)O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5C=C)c(C)c4C=C)c(C)c3CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D17 compound treatment 1028250.0 -79000.0 -0.39 972560.0 43000.0 0.26 956800.0 -56929.6875 -0.326064353696409 -0.2636 -0.4655 740 NINDS_000075 N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D18 compound treatment 1068580.0 -38700.0 -0.19 990960.0 61400.0 0.36 1019400.0 5670.3125 0.0324766718694735 0.1204 0.292 741 NINDS_000076 Cc1ccccc1OCC(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D19 compound treatment 989480.0 -118000.0 -0.58 901060.0 -28500.0 -0.17 963380.0 -50349.6875 -0.288377453565043 -0.5966 -0.8964 742 NINDS_000077 C[C@@H]1[C@H](O)CC[C@@]2(C)[C@H]1CC[C@@]3(C)C2[C@H](O)C[C@H]4/C(=C(/CCC=C(C)C)\C(=O)O)/[C@H](C[C@@]43C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D20 compound treatment 1026660.0 -80600.0 -0.39 831330.0 -98300.0 -0.58 897460.0 -116269.6875 -0.665933753969244 -0.9491 -0.979 743 NINDS_000078 CC(C)(C)NCC(O)c1cc(O)cc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D21 compound treatment 447150.0 -660000.0 -3.23 440210.0 -489000.0 -2.91 468610.0 -545119.6875 -3.12216887879239 -5.3448 -0.9991 26 NINDS_000079 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D22 compound treatment 325770.0 -781000.0 -3.82 308080.0 -622000.0 -3.7 242240.0 -771489.6875 -4.41870133817496 -6.8894 -0.9969 449 NINDS_000080 CC1=CC(=O)c2ccccc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D23 mock treatment 1046810.0 -60400.0 -0.3 886490.0 -43100.0 -0.26 989770.0 -23959.6875 -0.137228928570097 -0.3977 -0.9597 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 D24 mock treatment 944130.0 -163000.0 -0.8 935790.0 6210.0 0.04 964610.0 -49119.6875 -0.281332637886991 -0.6013 -0.7107 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E01 mock treatment 1211520.0 104000.0 0.51 958400.0 28800.0 0.17 1038150.0 24420.3125 0.139867154766603 0.4738 0.8531 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E02 mock treatment 1094740.0 -12500.0 -0.06 924810.0 -4770.0 -0.03 1084110.0 70380.3125 0.403102706444046 0.181 0.443 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E03 compound treatment 1055680.0 -51600.0 -0.25 891650.0 -37900.0 -0.23 966880.0 -46849.6875 -0.268331230090912 -0.4306 -0.9975 744 NINDS_000081 Cn1cnc2[nH]c(=O)n(C)c(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E04 compound treatment 506300.0 -601000.0 -2.94 482720.0 -447000.0 -2.66 497760.0 -515969.6875 -2.95521247471498 -4.9356 -0.9989 745 NINDS_000082 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E05 compound treatment 958680.0 -149000.0 -0.73 855480.0 -74100.0 -0.44 901670.0 -112059.6875 -0.641821010876075 -1.0441 -0.9809 746 NINDS_000083 C(N(Cc1ccccc1)c2ccccc2)C3=NCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E06 compound treatment 1120640.0 13400.0 0.07 1114180.0 185000.0 1.1 1062690.0 48960.3125 0.280419818782366 0.8334 0.7344 747 NINDS_000084 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCNCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E07 compound treatment 954970.0 -152000.0 -0.74 871540.0 -58000.0 -0.35 887650.0 -126079.6875 -0.722120454621022 -1.0458 -0.957 3043753 NINDS_000085 [O-][N+](=O)c1ccc(/C=N/N2CCOC2=O)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E08 compound treatment 1148560.0 41300.0 0.2 1061120.0 132000.0 0.78 1117760.0 104030.3125 0.595832826416761 0.9121 0.9087 749 NINDS_000086 NC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E09 compound treatment 1157630.0 50400.0 0.25 1062510.0 133000.0 0.79 1045760.0 32030.3125 0.183453372091784 0.7044 0.8307 750 NINDS_000087 CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1OC2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](NC(=N)N)[C@@H](O)[C@@H]3NC(=N)N)O[C@@H](C)[C@]2(O)C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E10 compound treatment 1190920.0 83700.0 0.41 979810.0 50200.0 0.3 1053440.0 39710.3125 0.227440513886449 0.5398 0.9725 751 NINDS_000088 COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E11 compound treatment 1092600.0 -14700.0 -0.07 963200.0 33600.0 0.2 1041250.0 27520.3125 0.157622381272262 0.1651 0.6243 752 NINDS_000089 CC1CCc2cc(F)cc3c(=O)c(cn1c23)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E12 compound treatment 1039570.0 -67700.0 -0.33 1049280.0 120000.0 0.71 1120800.0 107070.3125 0.613244403377149 0.5741 0.5764 753 NINDS_000090 O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E13 compound treatment 59560.0 -1050000.0 -5.12 70330.0 -859000.0 -5.11 58120.0 -955609.6875 -5.47324724276266 -9.0654 -0.9995 3173213 NINDS_000091 COc1ccc(C[C@H](N)C(=O)N[C@H]2[C@@H](O)C(O[C@@H]2CO)n3cnc4c(ncnc34)N(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E14 compound treatment 1054140.0 -53100.0 -0.26 992480.0 62900.0 0.37 1030180.0 16450.3125 0.0942190401697964 0.1205 0.2592 1000105 NINDS_000092 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E15 compound treatment 752960.0 -354000.0 -1.73 680070.0 -250000.0 -1.48 682660.0 -331069.6875 -1.89619912603876 -2.9508 -0.9951 755 NINDS_000093 CC(CN(C)C)CN1c2ccccc2CCc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E16 compound treatment 749220.0 -358000.0 -1.75 587120.0 -342000.0 -2.04 672320.0 -341409.6875 -1.95542139767376 -3.3147 -0.998 756 NINDS_000094 CCCCCCc1ccc(O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E17 compound treatment 1151520.0 44300.0 0.22 932520.0 2940.0 0.02 981080.0 -32649.6875 -0.187000837710153 0.027 0.0942 757 NINDS_000095 OC(=O)c1cn(C2CC2)c3cc(N4CCNCC4)c(F)cc3c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E18 compound treatment 439790.0 -667000.0 -3.26 416990.0 -513000.0 -3.05 460030.0 -553699.6875 -3.17131076376611 -5.4736 -0.9996 758 NINDS_000096 CCCOc1ccc2nc(NC(=O)OC)[nH]c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E19 compound treatment 1316960.0 210000.0 1.02 1003270.0 73700.0 0.44 966440.0 -47289.6875 -0.270851326756232 0.6882 0.6001 759 NINDS_000097 CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E20 compound treatment 1054890.0 -52400.0 -0.26 957310.0 27700.0 0.16 1008880.0 -4849.6875 -0.0277765484013425 -0.0686 -0.2243 760 NINDS_000098 N[C@@H]1CONC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E21 compound treatment 1091040.0 -16200.0 -0.08 882300.0 -47300.0 -0.28 1000600.0 -13129.6875 -0.0752001856487148 -0.2515 -0.8337 3173215 NINDS_000099 Cc1onc(c1C(=O)NC2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E22 compound treatment 1050420.0 -56800.0 -0.28 894650.0 -34900.0 -0.21 1023570.0 9840.3125 0.0563603152657951 -0.2477 -0.7051 762 NINDS_000100 COc1cccc(OC)c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E23 mock treatment 1059930.0 -47300.0 -0.23 929240.0 -345.0 0.0 1054810.0 41080.3125 0.235287178503466 0.0012 0.0035 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 E24 mock treatment 1098670.0 -8580.0 -0.04 896860.0 -32700.0 -0.19 1029830.0 16100.3125 0.0922144178223834 -0.0833 -0.3798 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F01 mock treatment 1019040.0 -88200.0 -0.43 906300.0 -23300.0 -0.14 959650.0 -54079.6875 -0.309741000296045 -0.5076 -0.9254 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F02 mock treatment 1136880.0 29600.0 0.14 917780.0 -11800.0 -0.07 1082850.0 69120.3125 0.395886065993359 0.2716 0.6356 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F03 compound treatment 48750.0 -1060000.0 -5.17 63090.0 -866000.0 -5.15 56890.0 -956839.6875 -5.48029205844071 -9.1248 -0.9996 763 NINDS_000101 CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc3ccc(OC)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F04 compound treatment 908700.0 -199000.0 -0.97 821150.0 -108000.0 -0.64 916090.0 -97639.6875 -0.559230570162656 -1.2552 -0.9714 382 NINDS_000102 NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F05 compound treatment 1094850.0 -12400.0 -0.06 927100.0 -2480.0 -0.01 939210.0 -74519.6875 -0.426810945384969 -0.2899 -0.6722 764 NINDS_000103 Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)n3c(=O)[nH]c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F06 compound treatment 1298210.0 191000.0 0.93 903120.0 -26500.0 -0.16 1071060.0 57330.3125 0.328358930347644 0.6374 0.6364 765 NINDS_000104 Oc1ccnc(S)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F07 compound treatment 1474400.0 367000.0 1.79 909230.0 -20400.0 -0.12 1017940.0 4210.3125 0.0241145329345504 0.9797 0.5449 766 NINDS_000105 CC12CCC3C(CCC4=CC(=O)CCC34C)C2CCC1(O)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F08 compound treatment 1116430.0 9180.0 0.04 921070.0 -8510.0 -0.05 996930.0 -16799.6875 -0.0962200828344463 -0.0589 -0.5008 767 NINDS_000106 OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OC(C#N)c3ccccc3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F09 compound treatment 1063370.0 -43900.0 -0.21 962720.0 33100.0 0.2 880270.0 -133459.6875 -0.764389348689332 -0.4513 -0.5518 768 NINDS_000107 C[N+](C)(C)CCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F10 compound treatment 729710.0 -378000.0 -1.84 645290.0 -284000.0 -1.69 691200.0 -322529.6875 -1.84728634076188 -3.1076 -0.9992 769 NINDS_000108 CCCCOc1ccc(CC(=O)NO)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F11 compound treatment 1240320.0 133000.0 0.65 876070.0 -53500.0 -0.32 1020130.0 6400.3125 0.0366577413369351 0.2128 0.2936 770 NINDS_000109 CC(CCc1ccccc1)NC(C)C(O)c2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F12 compound treatment 65340.0 -1040000.0 -5.09 204910.0 -725000.0 -4.31 210920.0 -802809.6875 -4.59808640080632 -8.0818 -0.9976 1000048 NINDS_000110 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F13 compound treatment 1093560.0 -13700.0 -0.07 740680.0 -189000.0 -1.12 807470.0 -206259.6875 -1.18135079695125 -1.3692 -0.8392 771 NINDS_000111 CN1CCC(=C2c3ccsc3C(=O)Cc4ccccc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F14 compound treatment 905940.0 -201000.0 -0.98 803520.0 -126000.0 -0.75 968370.0 -45359.6875 -0.259797266383354 -1.1507 -0.9106 772 NINDS_000112 CCN1CCCC(C1)OC(=O)C(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F15 compound treatment 513440.0 -594000.0 -2.9 435690.0 -494000.0 -2.94 518600.0 -495129.6875 -2.83585153265759 -5.008 -0.9999 773 NINDS_000113 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F16 compound treatment 317160.0 -790000.0 -3.86 324920.0 -605000.0 -3.6 359950.0 -653779.6875 -3.74451820527783 -6.4666 -0.9996 464 NINDS_000114 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F17 compound treatment 1019870.0 -87400.0 -0.43 865120.0 -64500.0 -0.38 974410.0 -39319.6875 -0.225203212159425 -0.5978 -0.9699 774 NINDS_000115 OC(=O)C1=CCNCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F18 compound treatment 1231460.0 124000.0 0.61 913050.0 -16500.0 -0.1 959850.0 -53879.6875 -0.308595501811809 0.1154 0.1678 775 NINDS_000116 NCC(O)CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F19 compound treatment 1195080.0 87800.0 0.43 832000.0 -97600.0 -0.58 954880.0 -58849.6875 -0.337061139145075 -0.2819 -0.3539 776 NINDS_000117 NNc1nncc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F20 compound treatment 1092000.0 -15300.0 -0.07 856500.0 -73100.0 -0.43 943600.0 -70129.6875 -0.401667253655988 -0.5258 -0.8816 777 NINDS_000118 Oc1ccc(cc1)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F21 compound treatment 738990.0 -368000.0 -1.8 631320.0 -298000.0 -1.77 707680.0 -306049.6875 -1.75289726566083 -3.0749 -0.9999 778 NINDS_000119 Oc1c(I)cc(I)c2cccnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F22 compound treatment 1416000.0 309000.0 1.51 922890.0 -6690.0 -0.04 1032430.0 18700.3125 0.107105898117452 0.9098 0.6014 779 NINDS_000120 CCN(CC)CCOC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F23 mock treatment 1073120.0 -34100.0 -0.17 919690.0 -9890.0 -0.06 1024890.0 11160.3125 0.063920605261753 -0.0933 -0.4964 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 F24 mock treatment 1131520.0 24300.0 0.12 915280.0 -14300.0 -0.09 1035310.0 21580.3125 0.123601076290451 0.0907 0.4743 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G01 mock treatment 1133440.0 26200.0 0.13 983650.0 54100.0 0.32 1065830.0 52100.3125 0.298404144984872 0.4318 0.945 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G02 mock treatment 1174420.0 67200.0 0.33 1014280.0 84700.0 0.5 1118600.0 104870.3125 0.600643920050553 0.827 0.9732 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G03 compound treatment 1192480.0 85200.0 0.42 961510.0 31900.0 0.19 1023390.0 9660.3125 0.0553293666299827 0.382 0.8286 780 NINDS_000121 CC(C)NNC(=O)c1ccncc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G04 compound treatment 1057250.0 -50000.0 -0.24 998480.0 68900.0 0.41 1175440.0 161710.3125 0.926194589270437 0.6302 0.6049 3173217 NINDS_000122 CCN1C[C@@]2(COC)C3[C@@H](OC)[C@H]4[C@@H]1[C@@]3(C5C[C@@]6(O)[C@H](OC(=O)c7ccccc7)C5[C@]4(OC(=O)C)[C@@H](O)[C@@H]6OC)C(C[C@H]2O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G05 compound treatment 1203550.0 96300.0 0.47 1003600.0 74000.0 0.44 1112580.0 98850.3125 0.566164415675048 0.8526 0.9941 782 NINDS_000123 CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)C=CC5(C)C4C(O)CC3(C)[C@@]2(O1)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G06 compound treatment 944160.0 -163000.0 -0.8 881720.0 -47900.0 -0.28 767560.0 -246169.6875 -1.40993501948056 -1.4384 -0.8748 783 NINDS_000124 CO[C@@]12C[C@@H](COC(=O)c3cncc(Br)c3)CN(C)[C@@H]2Cc4cn(C)c5cccc1c45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G07 compound treatment 652160.0 -455000.0 -2.22 558450.0 -371000.0 -2.21 632740.0 -380989.6875 -2.18211554770408 -3.8178 -1.0 784 NINDS_000125 Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G08 compound treatment 1056990.0 -50300.0 -0.25 991140.0 61600.0 0.37 1014950.0 1220.3125 0.0069893305952215 0.0736 0.1669 785 NINDS_000126 CC(CC(O)c1ccc(O)cc1)NCc2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G09 compound treatment 1177410.0 70200.0 0.34 976880.0 47300.0 0.28 937760.0 -75969.6875 -0.435115809395681 0.1091 0.1756 786 NINDS_000127 CN1CCN(CC(=O)N2c3ccccc3C(=O)Nc4cccnc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G10 compound treatment 1101120.0 -6130.0 -0.03 981980.0 52400.0 0.31 1045570.0 31840.3125 0.18236514853176 0.2679 0.7395 1981222 NINDS_000128 CCN1CCN(C(=O)NC(C(=O)NC2C3SCC(=C(N3C2=O)C(=O)O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G11 compound treatment 945610.0 -162000.0 -0.79 823200.0 -106000.0 -0.63 856510.0 -157219.6875 -0.900474568616574 -1.3411 -0.9901 382 NINDS_000129 NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G12 compound treatment 1139040.0 31800.0 0.16 1159680.0 230000.0 1.37 1020000.0 6270.3125 0.0359131673221817 0.9004 0.6536 1000106 NINDS_000130 O=C(C1CCCCC1)N2CC3N(CCc4ccccc34)C(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G13 compound treatment 1298350.0 191000.0 0.93 1000450.0 70900.0 0.42 1147850.0 134120.3125 0.768173073370074 1.2259 0.9574 789 NINDS_000131 C[N+]1(C)C2CC[C@H]1C[C@H](C2)OC(=O)C(O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G14 compound treatment 1112280.0 5030.0 0.02 1121770.0 192000.0 1.14 958560.0 -55169.6875 -0.315983967035132 0.4916 0.4145 790 NINDS_000132 COc1ccc2[C@@H](OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5cc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G15 compound treatment 927870.0 -179000.0 -0.88 832190.0 -97400.0 -0.58 832370.0 -181359.6875 -1.03873623566387 -1.4401 -0.9748 791 NINDS_000133 CC(C)Oc1ccc2c(=O)cc(oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G16 compound treatment 1149230.0 42000.0 0.21 1000290.0 70700.0 0.42 992000.0 -21729.6875 -0.124456620470865 0.2893 0.5976 792 NINDS_000134 COc1ccc2nccc([C@@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G17 compound treatment 701970.0 -405000.0 -1.98 592320.0 -337000.0 -2.01 632670.0 -381059.6875 -2.18251647217356 -3.5612 -0.999 793 NINDS_000135 CCN(CC)CCOC(=O)C(C1CCCCC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G18 compound treatment 1046810.0 -60400.0 -0.3 868530.0 -61100.0 -0.36 959430.0 -54299.6875 -0.311001048628705 -0.5597 -0.996 794 NINDS_000136 Nc1cc(c[nH]c1=O)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G19 compound treatment 1310680.0 203000.0 0.99 943290.0 13700.0 0.08 969950.0 -43779.6875 -0.250747828357889 0.4761 0.463 795 NINDS_000137 CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G20 compound treatment 1142780.0 35500.0 0.17 1019840.0 90300.0 0.54 1050580.0 36850.3125 0.211059885561873 0.5319 0.8832 796 NINDS_000138 Cc1ccc(C)c(OCCCC(C)(C)C(=O)O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G21 compound treatment 439210.0 -668000.0 -3.26 385570.0 -544000.0 -3.24 423200.0 -590529.6875 -3.38225430963818 -5.7049 -0.9998 797 NINDS_000139 CC[C@]1(CC[C@@H](O1)[C@]2(C)CCC3(C[C@H](O)[C@@H](C)[C@H](O3)[C@H](C)[C@@H](OC)[C@H](C)C(=O)O)O2)C4O[C@H](C[C@@H]4C)C5O[C@@](O)(CC)[C@H](C)C[C@@H]5C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G22 compound treatment 1020980.0 -86300.0 -0.42 795870.0 -134000.0 -0.8 861670.0 -152059.6875 -0.870920707723285 -1.2053 -0.9624 798 NINDS_000140 CCCCCCOc1ccccc1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G23 mock treatment 1051430.0 -55800.0 -0.27 941520.0 11900.0 0.07 1024660.0 10930.3125 0.0626032820048816 -0.0803 -0.2783 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 G24 mock treatment 1297250.0 190000.0 0.93 926810.0 -2770.0 -0.02 1048560.0 34830.3125 0.199490350871089 0.6416 0.6756 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H01 mock treatment 1321440.0 214000.0 1.05 906300.0 -23300.0 -0.14 974470.0 -39259.6875 -0.224859562614154 0.3944 0.3654 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H02 mock treatment 1237520.0 130000.0 0.64 978960.0 49400.0 0.29 1165440.0 151710.3125 0.868919665058635 1.0387 0.9304 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H03 compound treatment 1089530.0 -17700.0 -0.09 907880.0 -21700.0 -0.13 1061800.0 48070.3125 0.275322350527515 0.0344 0.109 799 NINDS_000141 Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H04 compound treatment 696690.0 -411000.0 -2.01 643650.0 -286000.0 -1.7 719840.0 -293889.6875 -1.68325095781928 -3.1116 -0.9966 800 NINDS_000142 C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H05 compound treatment 344250.0 -763000.0 -3.73 206580.0 -723000.0 -4.3 230240.0 -783489.6875 -4.48743124722912 -7.2254 -0.997 801 NINDS_000143 CN(C)CC/C=C/1\c2ccccc2Sc3ccc(Cl)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H06 compound treatment 701280.0 -406000.0 -1.98 675100.0 -254000.0 -1.51 663720.0 -350009.6875 -2.00467783249591 -3.1763 -0.9924 802 NINDS_000144 Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H07 compound treatment 1344380.0 237000.0 1.16 1091680.0 162000.0 0.96 1074970.0 61240.3125 0.350753425714459 1.4279 0.9228 803 NINDS_000145 CCc1cc(ccn1)C(=S)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H08 compound treatment 428700.0 -679000.0 -3.32 423840.0 -506000.0 -3.01 360110.0 -653619.6875 -3.74360180649044 -5.8118 -0.996 804 NINDS_000146 COc1c(C)c2COC(=O)c2c(O)c1C/C=C(\C)/CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H09 compound treatment 1350920.0 244000.0 1.19 869940.0 -59600.0 -0.35 1089810.0 76080.3125 0.435749413244774 0.7341 0.5577 805 NINDS_000147 CCc1cccc2c3CCOC(CC)(CC(=O)O)c3[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H10 compound treatment 1038940.0 -68300.0 -0.33 886340.0 -43200.0 -0.26 1012360.0 -1369.6875 -0.0078448747756353 -0.3457 -0.8203 806 NINDS_000148 OC(=O)C1CCCNC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H11 compound treatment 1037300.0 -70000.0 -0.34 890020.0 -39600.0 -0.24 1057640.0 43910.3125 0.251495982055406 -0.188 -0.3874 807 NINDS_000149 CCCc1ncc(C[n+]2ccccc2C)c(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H12 compound treatment 1114150.0 6900.0 0.03 778690.0 -151000.0 -0.9 953500.0 -60229.6875 -0.344965078686304 -0.6978 -0.7254 1000107 NINDS_000150 CC(=O)O[C@]1(CCC2C3CCC4=CC(=O)CC[C@@H]4C3CC[C@@]21C)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H13 compound treatment 72130.0 -1040000.0 -5.06 75870.0 -854000.0 -5.08 72560.0 -941169.6875 -5.39054225220082 -8.9632 -0.9996 809 NINDS_000151 CNCCC=C1c2ccccc2CCc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H14 compound treatment 1079790.0 -27500.0 -0.13 817780.0 -112000.0 -0.66 786400.0 -227329.6875 -1.30202906226552 -1.213 -0.8263 810 NINDS_000152 CCCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2O)[C@@H](C)OC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H15 compound treatment 1097700.0 -9550.0 -0.05 920260.0 -9320.0 -0.06 1054190.0 40460.3125 0.231736133202334 0.0748 0.3082 811 NINDS_000153 CC(=O)[C@H]1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H16 compound treatment 817380.0 -290000.0 -1.42 736750.0 -193000.0 -1.15 799530.0 -214199.6875 -1.22682708677542 -2.188 -0.996 812 NINDS_000154 COC1=CC(=O)C[C@@H](C)[C@@]21Oc3c(C2=O)c(OC)cc(OC)c3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H17 compound treatment 1238920.0 132000.0 0.64 917090.0 -12500.0 -0.07 808430.0 -205299.6875 -1.17585240422692 -0.3504 -0.261 813 NINDS_000155 CC(=O)O[C@H]1CCC2C3CCc4cc(OC(=O)C)ccc4C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H18 compound treatment 436670.0 -671000.0 -3.28 278400.0 -651000.0 -3.87 421760.0 -591969.6875 -3.39050189872468 -6.0848 -0.9973 814 NINDS_000156 Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H19 compound treatment 1016770.0 -90500.0 -0.44 870340.0 -59200.0 -0.35 952910.0 -60819.6875 -0.3483442992148 -0.6598 -0.9936 815 NINDS_000157 CCN(CC)C(=O)c1cccc(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H20 compound treatment 951840.0 -155000.0 -0.76 816970.0 -113000.0 -0.67 822050.0 -191679.6875 -1.09784395745045 -1.4589 -0.9769 816 NINDS_000158 Cc1cc(cc(C)c1CC2=NCCN2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H21 compound treatment 1119570.0 12300.0 0.06 916840.0 -12700.0 -0.08 1006720.0 -7009.6875 -0.0401479320310918 -0.0322 -0.3072 3173342 NINDS_000159 CO/N=C(/C(=O)NC1C2SCC(=C(N2C1=O)C(=O)O)COC(=O)N)\c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H22 compound treatment 1042140.0 -65100.0 -0.32 877960.0 -51600.0 -0.31 1009610.0 -4119.6875 -0.0235954789338809 -0.3745 -0.846 82 NINDS_000160 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H23 mock treatment 1174560.0 67300.0 0.33 916430.0 -13200.0 -0.08 1003640.0 -10089.6875 -0.0577886086883269 0.1113 0.3247 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 H24 mock treatment 1145050.0 37800.0 0.18 945330.0 15700.0 0.09 986240.0 -27489.6875 -0.157446976816863 0.0698 0.2682 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I01 mock treatment 1140650.0 33400.0 0.16 941390.0 11800.0 0.07 999520.0 -14209.6875 -0.0813858774635895 0.0878 0.4491 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I02 mock treatment 1078880.0 -28400.0 -0.14 994640.0 65100.0 0.39 1134200.0 120470.3125 0.689992801820964 0.5417 0.6745 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I03 compound treatment 1014010.0 -93200.0 -0.46 907080.0 -22500.0 -0.13 1094240.0 80510.3125 0.461122204670602 -0.0741 -0.1119 818 NINDS_000161 CCC1(CC)C(=O)NC=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I04 compound treatment 494990.0 -612000.0 -2.99 564190.0 -365000.0 -2.17 582620.0 -431109.6875 -2.46917746785363 -4.4072 -0.9913 819 NINDS_000162 CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I05 compound treatment 133500.0 -974000.0 -4.76 140480.0 -789000.0 -4.69 103700.0 -910029.6875 -5.21218813820527 -8.4652 -0.9989 820 NINDS_000163 Oc1ccc(Cl)c2cccnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I06 compound treatment 1024480.0 -82800.0 -0.4 891840.0 -37700.0 -0.22 1027400.0 13670.3125 0.0782966112389154 -0.3179 -0.6776 821 NINDS_000164 O=C1NS(=O)(=O)c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I07 compound treatment 1326640.0 219000.0 1.07 1144800.0 215000.0 1.28 1180050.0 166320.3125 0.952598329332078 1.9077 0.9926 822 NINDS_000165 CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I08 compound treatment 1125480.0 18200.0 0.09 906980.0 -22600.0 -0.13 999920.0 -13809.6875 -0.0790948804951174 -0.0719 -0.4001 2081029 NINDS_000166 CN/C(=N\C#N)/NCCSCc1nc[nH]c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I09 compound treatment 1317860.0 211000.0 1.03 938720.0 9140.0 0.05 1002250.0 -11479.6875 -0.0657498231537674 0.5875 0.569 824 NINDS_000167 CC[C@]1(CCCN2CCc3c4[C@@H]21)C[C@@](O)(C(=O)OC)n4c5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I10 compound treatment 715610.0 -392000.0 -1.91 641070.0 -289000.0 -1.72 690450.0 -323279.6875 -1.85158196007776 -3.1643 -0.999 825 NINDS_000168 CC(Cc1ccc(O)c(O)c1)(NN)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I11 compound treatment 1227200.0 120000.0 0.59 999150.0 69600.0 0.41 951680.0 -62049.6875 -0.355389114892852 0.372 0.4647 826 NINDS_000169 CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)CC[C@]5(C)C4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I12 compound treatment 280960.0 -826000.0 -4.04 263870.0 -666000.0 -3.96 258110.0 -755619.6875 -4.32780603345083 -7.1151 -0.9993 1000036 NINDS_000170 CC[C@H]1CN2CCc3cc(OC)c(OC)cc3C2C[C@@H]1CC4NCCc5cc(OC)c(OC)cc45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I13 compound treatment 1089560.0 -17700.0 -0.09 973020.0 43400.0 0.26 1113600.0 99870.3125 0.572006457944651 0.4295 0.6779 827 NINDS_000171 CCCCC1(COC(=O)CCC(=O)O)C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I14 compound treatment 45940.0 -1060000.0 -5.19 48030.0 -882000.0 -5.24 41840.0 -971889.6875 -5.56649081937947 -9.2342 -0.9995 3173346 NINDS_000172 CC[C@H](C1OC(CC)(C[C@@H]1C)C2CC[C@](O)(CC)[C@H](C)O2)C(=O)C(C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I15 compound treatment 155460.0 -952000.0 -4.65 155070.0 -775000.0 -4.61 168020.0 -845709.6875 -4.84379582567495 -8.1405 -0.9998 829 NINDS_000173 CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I16 compound treatment 1185600.0 78300.0 0.38 873290.0 -56300.0 -0.33 948230.0 -65499.6875 -0.375148963745924 -0.1889 -0.2989 362 NINDS_000174 CCN(CC)CC(=O)Nc1c(C)cccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I17 compound treatment 1043050.0 -64200.0 -0.31 836000.0 -93600.0 -0.56 925760.0 -87969.6875 -0.503845718449843 -0.7933 -0.975 830 NINDS_000175 COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I18 compound treatment 1028090.0 -79200.0 -0.39 1038320.0 109000.0 0.65 1076690.0 62960.3125 0.360604712678889 0.3582 0.4288 831 NINDS_000176 Nc1nccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I19 compound treatment 950080.0 -157000.0 -0.77 824640.0 -105000.0 -0.62 1007300.0 -6429.6875 -0.0368259864268073 -0.8249 -0.8331 832 NINDS_000177 CCCn1c(=O)n(CCC)c2[nH]c(nc2c1=O)C3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I20 compound treatment 1233390.0 126000.0 0.62 883460.0 -46100.0 -0.27 1046280.0 32550.3125 0.186431668150798 0.3051 0.4359 833 NINDS_000178 CC(C)(C)NC[C@@H](O)COc1nsnc1N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I21 compound treatment 1080600.0 -26700.0 -0.13 900890.0 -28700.0 -0.17 1058360.0 44630.3125 0.255619776598655 -0.0261 -0.0782 834 NINDS_000179 CC(C[N+](C)(C)C)OC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I22 compound treatment 1178270.0 71000.0 0.35 881760.0 -47800.0 -0.28 1004800.0 -8929.6875 -0.0511447174797579 0.0066 0.0146 835 NINDS_000180 CC(=O)OC1CN2CCC1CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I23 mock treatment 1321540.0 214000.0 1.05 863100.0 -66500.0 -0.4 1045470.0 31740.3125 0.181792399289642 0.4812 0.4244 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 I24 mock treatment 1189060.0 81800.0 0.4 951720.0 22100.0 0.13 983250.0 -30479.6875 -0.174572179156192 0.206 0.4521 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J01 mock treatment 1296680.0 189000.0 0.93 936070.0 6490.0 0.04 1045840.0 32110.3125 0.183911571485479 0.6628 0.7018 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J02 mock treatment 1066270.0 -41000.0 -0.2 940560.0 11000.0 0.07 1102720.0 88990.3125 0.509691340402211 0.2163 0.3923 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J03 compound treatment 1527380.0 420000.0 2.05 956550.0 27000.0 0.16 1217180.0 203450.3125 1.1652601229305 1.9504 0.8244 836 NINDS_000181 CNC(C)C(O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J04 compound treatment 1331790.0 225000.0 1.1 954660.0 25100.0 0.15 1088480.0 74750.3125 0.428131848324604 0.9667 0.8143 1000042 NINDS_000182 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J05 compound treatment 859310.0 -248000.0 -1.21 748920.0 -181000.0 -1.07 754470.0 -259259.6875 -1.48490789527381 -2.177 -0.9909 837 NINDS_000183 CCOc1ccc2NC(C)(C)C=C(C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J06 compound treatment 1046430.0 -60800.0 -0.3 752070.0 -178000.0 -1.06 832720.0 -181009.6875 -1.03673161331645 -1.3796 -0.9142 838 NINDS_000184 COc1ccc(C(=O)c2ccccc2)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J07 compound treatment 1156960.0 49700.0 0.24 899960.0 -29600.0 -0.18 958980.0 -54749.6875 -0.313578420218236 -0.1425 -0.3284 839 NINDS_000185 Nc1nc2n(COCCO)cnc2c(=O)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J08 compound treatment 1139580.0 32300.0 0.16 942880.0 13300.0 0.08 1039260.0 25530.3125 0.146224671354113 0.2213 0.9649 840 NINDS_000186 CCOc1ccc2ccccc2c1NC(=O)[C@H]3[C@H]4SC(C)(C)C(N4C3=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J09 compound treatment 1320380.0 213000.0 1.04 970650.0 41100.0 0.24 1091750.0 78020.3125 0.446860748541863 1.0002 0.8629 841 NINDS_000187 C/C(=C(/CCOP(=O)(O)O)\SC(=O)c1ccccc1)/N(Cc2cnc(C)nc2N)C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J10 compound treatment 1220110.0 113000.0 0.55 915540.0 -14000.0 -0.08 1023130.0 9400.3125 0.0538402186004758 0.3012 0.5376 842 NINDS_000188 Cn1cc[nH]c1=S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J11 compound treatment 1603220.0 496000.0 2.42 1048800.0 119000.0 0.71 1104390.0 90660.3125 0.519256252745582 2.1081 0.8179 1000108 NINDS_000189 NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J12 compound treatment 891360.0 -216000.0 -1.05 742900.0 -187000.0 -1.11 762460.0 -251269.6875 -1.43914523082858 -2.0808 -0.9902 844 NINDS_000190 CNCCCN1c2ccccc2CCc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J13 compound treatment 1040280.0 -67000.0 -0.33 931840.0 2260.0 0.01 921500.0 -92229.6875 -0.528244836164071 -0.4862 -0.7822 1000109 NINDS_000191 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J14 compound treatment 846290.0 -261000.0 -1.28 633870.0 -296000.0 -1.76 692010.0 -321719.6875 -1.84264707190072 -2.8152 -0.9884 846 NINDS_000192 Cc1nc2sccn2c(=O)c1CCN3CCC(=C(c4ccc(F)cc4)c5ccc(F)cc5)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J15 compound treatment 1325970.0 219000.0 1.07 966470.0 36900.0 0.22 953190.0 -60539.6875 -0.34674060133687 0.5434 0.4747 847 NINDS_000193 CC(=CCC/C(=C/CO)/C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J16 compound treatment 1346030.0 239000.0 1.17 986120.0 56500.0 0.34 931430.0 -82299.6875 -0.471370836421751 0.5955 0.4572 848 NINDS_000194 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J17 compound treatment 130930.0 -976000.0 -4.77 85060.0 -845000.0 -5.02 95800.0 -917929.6875 -5.25743532833259 -8.6889 -0.9992 3045136 NINDS_000195 CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)C(CCC3C[C@@H](O)CC(=O)O3)[C@@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J18 compound treatment 942430.0 -165000.0 -0.81 739070.0 -191000.0 -1.13 773280.0 -240449.6875 -1.37717376283141 -1.9141 -0.9783 850 NINDS_000196 Clc1cccc(c1)N2CCN(CCCn3nc4ccccn4c3=O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J19 compound treatment 1249380.0 142000.0 0.69 897830.0 -31800.0 -0.19 1122120.0 108390.3125 0.620804693373107 0.6503 0.6843 1635952 NINDS_000197 Cn1nnnc1SCC2=C(N3C(SC2)C(NC(=O)C(O)c4ccccc4)C3=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J20 compound treatment 1305000.0 198000.0 0.97 953790.0 24200.0 0.14 991850.0 -21879.6875 -0.125315744334042 0.5686 0.5773 822 NINDS_000198 CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J21 compound treatment 1012820.0 -94400.0 -0.46 665760.0 -264000.0 -1.57 762720.0 -251009.6875 -1.43765608279907 -2.0022 -0.9195 852 NINDS_000199 CCOc1ccc(Cc2nccc3cc(OCC)c(OCC)cc23)cc1OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J22 compound treatment 924900.0 -182000.0 -0.89 765840.0 -164000.0 -0.97 957920.0 -55809.6875 -0.319649562184687 -1.2611 -0.9287 1000110 NINDS_000200 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J23 mock treatment 1074490.0 -32800.0 -0.16 926180.0 -3400.0 -0.02 1058240.0 44510.3125 0.254932477508114 0.0431 0.1428 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 J24 mock treatment 1252260.0 145000.0 0.71 893820.0 -35800.0 -0.21 1016550.0 2820.3125 0.0161533184691099 0.2956 0.3995 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K01 mock treatment 1233550.0 126000.0 0.62 1054650.0 125000.0 0.74 999090.0 -14639.6875 -0.083848699204697 0.7372 0.76 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K02 mock treatment 1194340.0 87100.0 0.43 980430.0 50800.0 0.3 1142030.0 128300.3125 0.734839067478805 0.8445 0.9369 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K03 compound treatment 1276000.0 169000.0 0.82 1087120.0 158000.0 0.94 1219260.0 205530.3125 1.17717330716655 1.6965 0.9889 3045140 NINDS_000201 CC(C)[N+]1(C)C2CC[C@@H]1C[C@H](C2)OC(=O)C(CO)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K04 compound treatment 1274790.0 168000.0 0.82 1075800.0 146000.0 0.87 1016210.0 2480.3125 0.0142059710459086 0.9828 0.8229 3173462 NINDS_000202 C[C@H](COc1ccccc1)N[C@@H](C)[C@H](O)c2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K05 compound treatment 1357940.0 251000.0 1.22 1000600.0 71000.0 0.42 1009500.0 -4229.6875 -0.0242255031002108 0.937 0.7231 856 NINDS_000203 Cn1c(=O)n(C)c2nc[nH]c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K06 compound treatment 1026410.0 -80800.0 -0.39 940370.0 10800.0 0.06 929570.0 -84159.6875 -0.482023972325147 -0.4693 -0.7491 857 NINDS_000204 O=C(OCc1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K07 compound treatment 1115010.0 7760.0 0.04 1010080.0 80500.0 0.48 1222150.0 208420.3125 1.19372576026377 0.9874 0.7674 858 NINDS_000205 OCC(O)CN1CCN(CC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K08 compound treatment 1373720.0 266000.0 1.3 952320.0 22700.0 0.14 1038410.0 24680.3125 0.14135630279611 0.9113 0.6922 859 NINDS_000206 CC(=O)O[C@@]1(CCC2C3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)C3CC[C@@]21C)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K09 compound treatment 1436160.0 329000.0 1.61 1041890.0 112000.0 0.67 1026940.0 13210.3125 0.0756619647251725 1.357 0.7791 860 NINDS_000207 CN(C)C(=O)Oc1ccc[n+](C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K10 compound treatment 1302770.0 196000.0 0.96 906360.0 -23200.0 -0.14 1000060.0 -13669.6875 -0.0782930315561522 0.4266 0.4405 861 NINDS_000208 C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K11 compound treatment 63950.0 -1040000.0 -5.1 76760.0 -853000.0 -5.07 77810.0 -935919.6875 -5.36047291698962 -8.9658 -0.9997 862 NINDS_000209 CCCCCCCCCCCCCCCC[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K12 compound treatment 848800.0 -258000.0 -1.26 613730.0 -316000.0 -1.88 636160.0 -377569.6875 -2.16252752362364 -3.062 -0.9782 863 NINDS_000210 CN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K13 compound treatment 1289390.0 182000.0 0.89 951750.0 22200.0 0.13 1105610.0 91880.3125 0.526243793499421 0.8937 0.8575 864 NINDS_000211 Oc1noc2CNCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K14 compound treatment 1351010.0 244000.0 1.19 1069340.0 140000.0 0.83 1193440.0 179710.3125 1.02928945285168 1.7617 0.9897 196 NINDS_000212 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K15 compound treatment 1196880.0 89600.0 0.44 912240.0 -17300.0 -0.1 1033640.0 19910.3125 0.11403616394708 0.2591 0.5583 865 NINDS_000213 Cc1ccc(cc1)C(=O)c2ccc(CC(=O)O)n2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K16 compound treatment 1256820.0 150000.0 0.73 879420.0 -50200.0 -0.3 1046240.0 32510.3125 0.186202568453951 0.3572 0.4404 866 NINDS_000214 Cc1c(cc(cc1[N+](=O)[O-])[N+](=O)[O-])C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K17 compound treatment 65350.0 -1040000.0 -5.09 84080.0 -846000.0 -5.03 74750.0 -938979.6875 -5.37799904379843 -8.9469 -0.9996 80 NINDS_000215 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K18 compound treatment 1372450.0 265000.0 1.3 992330.0 62700.0 0.37 1100010.0 86280.3125 0.494169835940812 1.2488 0.8696 867 NINDS_000216 Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K19 compound treatment 1429040.0 322000.0 1.57 895100.0 -34500.0 -0.21 1006780.0 -6949.6875 -0.039804282485821 0.7663 0.4832 868 NINDS_000217 CNC1(CCCCC1=O)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K20 compound treatment 1115040.0 7790.0 0.04 956400.0 26800.0 0.16 1057510.0 43780.3125 0.250751408040652 0.2588 0.8639 869 NINDS_000218 CCC1(C)CC(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K21 compound treatment 1220970.0 114000.0 0.56 879080.0 -50500.0 -0.3 977390.0 -36339.6875 -0.208135284744308 0.0272 0.0409 870 NINDS_000219 OC(=O)/C(=C/c1ccc(O)cc1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K22 compound treatment 460580.0 -647000.0 -3.16 443760.0 -486000.0 -2.89 451260.0 -562469.6875 -3.22154087229986 -5.3521 -0.9989 871 NINDS_000220 Clc1ccc(CSC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K23 mock treatment 1098920.0 -8330.0 -0.04 875810.0 -53800.0 -0.32 969130.0 -44599.6875 -0.255444372143257 -0.3556 -0.8646 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 K24 mock treatment 1105350.0 -1900.0 -0.01 984280.0 54700.0 0.33 1010010.0 -3719.6875 -0.0213044819654088 0.1701 0.5217 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L01 mock treatment 1288380.0 181000.0 0.88 888820.0 -40800.0 -0.24 1018090.0 4360.3125 0.0249736567977274 0.3854 0.4199 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L02 mock treatment 1092860.0 -14400.0 -0.07 954610.0 25000.0 0.15 1032380.0 18650.3125 0.106819523496393 0.107 0.5453 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L03 compound treatment 1479130.0 372000.0 1.82 1038560.0 109000.0 0.65 1145640.0 131910.3125 0.755515315119266 1.8593 0.8975 872 NINDS_000221 CCN(CC)CCOC(=O)C(c1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L04 compound treatment 1175740.0 68500.0 0.33 955390.0 25800.0 0.15 1176320.0 162590.3125 0.931234782601076 0.8194 0.8183 873 NINDS_000222 Nc1nc(=O)c2N(C=O)C(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)CNc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L05 compound treatment 1198820.0 91600.0 0.45 990930.0 61300.0 0.36 1088080.0 74350.3125 0.425840851356132 0.7148 0.9964 874 NINDS_000223 CC(C)CC(NC(=O)CCN)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L06 compound treatment 1220880.0 114000.0 0.56 916720.0 -12900.0 -0.08 1010620.0 -3109.6875 -0.0178107115884889 0.2661 0.4745 3173466 NINDS_000224 [O-][N+](=O)c1ccc(/C=N/N2CC(=O)NC2=O)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L07 compound treatment 1104870.0 -2380.0 -0.01 944760.0 15200.0 0.09 1071450.0 57720.3125 0.330592652391905 0.2362 0.689 876 NINDS_000225 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L08 compound treatment 1100260.0 -6990.0 -0.03 1076930.0 147000.0 0.88 1140480.0 126750.3125 0.725961454225976 0.9053 0.7952 877 NINDS_000226 CC(C)(Oc1ccc(Cl)cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L09 compound treatment 1143360.0 36100.0 0.18 891740.0 -37800.0 -0.23 1028530.0 14800.3125 0.0847686776748491 0.0209 0.07 878 NINDS_000227 CC(=O)NS(=O)(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L10 compound treatment 1016600.0 -90700.0 -0.44 837460.0 -92100.0 -0.55 943250.0 -70479.6875 -0.403671876003401 -0.8051 -0.9915 3173468 NINDS_000228 COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L11 compound treatment 1177600.0 70300.0 0.34 1004890.0 75300.0 0.45 1164090.0 150360.3125 0.861187550290041 0.9542 0.9267 3263 NINDS_000229 CNC(C)(C)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L12 compound treatment 954950.0 -152000.0 -0.74 748730.0 -181000.0 -1.08 795200.0 -218529.6875 -1.25162712895913 -1.7732 -0.9795 879 NINDS_000230 NC[C@H](O)c1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L13 compound treatment 1492270.0 385000.0 1.88 1155490.0 226000.0 1.34 1257400.0 243670.3125 1.39561986811037 2.6674 0.9879 3045196 NINDS_000231 CC1(C)S[C@@H]2[C@H](NC(=O)[C@@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L14 compound treatment 1336350.0 229000.0 1.12 929700.0 115.0 0.0 1031710.0 17980.3125 0.102982103574202 0.7061 0.6282 881 NINDS_000232 CC12C[C@H](O)C3C(CCC4=CC(=O)CCC34C)C2CC[C@]1(O)C(=O)COP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L15 compound treatment 906720.0 -201000.0 -0.98 749340.0 -180000.0 -1.07 817920.0 -195809.6875 -1.12149850114992 -1.832 -0.9985 882 NINDS_000233 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L16 compound treatment 1251440.0 144000.0 0.7 885310.0 -44300.0 -0.26 1018880.0 5150.3125 0.0294983758104598 0.2718 0.3611 883 NINDS_000234 CC(Oc1ccccc1)C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L17 compound treatment 1152040.0 44800.0 0.22 945220.0 15600.0 0.09 1058470.0 44740.3125 0.256249800764985 0.328 0.9382 884 NINDS_000235 CN(C)CCC(c1ccccc1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L18 compound treatment 924680.0 -183000.0 -0.89 651480.0 -278000.0 -1.65 773460.0 -240269.6875 -1.37614281419559 -2.2643 -0.9722 885 NINDS_000236 Clc1ccc2Oc3ccccc3N=C(N4CCNCC4)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L19 compound treatment 1486760.0 380000.0 1.85 1077440.0 148000.0 0.88 1124480.0 110750.3125 0.634321575487092 1.9444 0.9052 886 NINDS_000237 O[C@@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L20 compound treatment 1116880.0 9630.0 0.05 781140.0 -148000.0 -0.88 807460.0 -206269.6875 -1.18140807187546 -1.1646 -0.7893 3173471 NINDS_000238 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2CC[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L21 compound treatment 1192590.0 85300.0 0.42 892480.0 -37100.0 -0.22 1011130.0 -2599.6875 -0.014889690453687 0.1047 0.2219 887 NINDS_000239 COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L22 compound treatment 1140520.0 33300.0 0.16 896360.0 -33200.0 -0.2 982970.0 -30759.6875 -0.176175877034122 -0.1219 -0.3926 888 NINDS_000240 CC(C)[N+](C)(CCC(C(=O)N)(c1ccccc1)c2ccccc2)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L23 mock treatment 1099120.0 -8130.0 -0.04 875130.0 -54500.0 -0.32 1046250.0 32520.3125 0.186259843378163 -0.1024 -0.2725 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 L24 mock treatment 1084520.0 -22700.0 -0.11 940880.0 11300.0 0.07 1087160.0 73430.3125 0.420571558328646 0.2175 0.4941 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M01 mock treatment 1209970.0 103000.0 0.5 1058320.0 129000.0 0.77 1047580.0 33850.3125 0.193877408298332 0.8437 0.9017 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M02 mock treatment 1121300.0 14000.0 0.07 1023750.0 94200.0 0.56 1044320.0 30590.3125 0.175205783005285 0.4641 0.7856 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M03 compound treatment 1125150.0 17900.0 0.09 917190.0 -12400.0 -0.07 1162440.0 148710.3125 0.851737187795094 0.4997 0.5814 889 NINDS_000241 NC(=O)c1cnccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M04 compound treatment 1376960.0 270000.0 1.32 975320.0 45700.0 0.27 1070600.0 56870.3125 0.325724283833901 1.1059 0.7988 890 NINDS_000242 COc1ccc2cc(ccc2c1)[C@H](C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M05 compound treatment 1263960.0 157000.0 0.77 969180.0 39600.0 0.24 1080400.0 66670.3125 0.381853709561468 0.7984 0.8998 891 NINDS_000243 CC(=O)OCC(=O)[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M06 compound treatment 97170.0 -1010000.0 -4.94 102900.0 -827000.0 -4.92 87200.0 -926529.6875 -5.30669176315474 -8.7513 -0.9994 892 NINDS_000244 C[n+]1c2cc(N)ccc2cc3ccc(N)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M07 compound treatment 1198520.0 91300.0 0.45 876700.0 -52900.0 -0.31 992720.0 -21009.6875 -0.120332825927615 0.0064 0.0115 893 NINDS_000245 NCC(O)c1ccc(O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M08 compound treatment 1339270.0 232000.0 1.13 1128770.0 199000.0 1.18 1029410.0 15680.3125 0.0898088710054877 1.3902 0.8467 894 NINDS_000246 ClCCN(CCCl)P1(=O)NCCCO1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M09 compound treatment 1455840.0 349000.0 1.7 986590.0 57000.0 0.34 1040220.0 26490.3125 0.151723064078446 1.2666 0.7266 895 NINDS_000247 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C[C@H](Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M10 compound treatment 1398920.0 292000.0 1.43 898500.0 -31100.0 -0.18 1004640.0 -9089.6875 -0.0520611162671467 0.686 0.4771 896 NINDS_000248 COc1ccccc1OCC(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M11 compound treatment 1238720.0 131000.0 0.64 826330.0 -103000.0 -0.61 900890.0 -112839.6875 -0.646288454964596 -0.3568 -0.3247 897 NINDS_000249 CCCCCCCCCCCCCCCC(=O)OC/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M12 compound treatment 1253320.0 146000.0 0.71 984650.0 55100.0 0.33 1146330.0 132600.3125 0.75946728488988 1.0396 0.9516 898 NINDS_000250 CCOC(=O)C(Cc1ccc(O)cc1)NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M13 compound treatment 425280.0 -682000.0 -3.33 239110.0 -690000.0 -4.11 254290.0 -759439.6875 -4.34968505449973 -6.8056 -0.994 1011303 NINDS_000251 CN1CCc2cccc-3c2C1Cc4ccc(O)c(O)c43 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M14 compound treatment 1203430.0 96200.0 0.47 1038240.0 109000.0 0.65 1112120.0 98390.3125 0.563529769161305 0.9697 0.9918 900 NINDS_000252 CN1C(=C(O)c2sccc2S1(=O)=O)C(=O)Nc3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M15 compound treatment 929890.0 -177000.0 -0.87 729760.0 -200000.0 -1.19 786900.0 -226829.6875 -1.29916531605493 -1.9364 -0.9868 901 NINDS_000253 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M16 compound treatment 1377150.0 270000.0 1.32 1048590.0 119000.0 0.71 1070080.0 56350.3125 0.322745987774888 1.3562 0.8859 3173593 NINDS_000254 CN1CCCN=C1/C=C/c2cccs2.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M17 compound treatment 1459520.0 352000.0 1.72 853920.0 -75700.0 -0.45 1056120.0 42390.3125 0.242790193575212 0.8741 0.4868 902 NINDS_000255 OC(=O)c1cc2cc(Cc3cccnc3)ccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M18 compound treatment 93170.0 -1010000.0 -4.95 71860.0 -858000.0 -5.1 87220.0 -926509.6875 -5.30657721330632 -8.8691 -0.9996 3173594 NINDS_000256 CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)/C(=C/C=C\[C@@H](OC)[C@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M19 compound treatment 501280.0 -606000.0 -2.96 419220.0 -510000.0 -3.03 70930.0 -942799.6875 -5.39987806484734 -6.5792 -0.9583 903 NINDS_000257 COC(=O)Nc1nc2ccc(Sc3ccccc3)cc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M20 compound treatment 64710.0 -1040000.0 -5.09 71620.0 -858000.0 -5.1 58630.0 -955099.6875 -5.47032622162786 -9.0447 -0.9994 368 NINDS_000258 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M21 compound treatment 1359880.0 253000.0 1.23 930190.0 605.0 0.0 995110.0 -18619.6875 -0.106644119040994 0.6531 0.5272 904 NINDS_000259 NC(=O)CN1CCCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M22 compound treatment 1236160.0 129000.0 0.63 894880.0 -34700.0 -0.21 1041720.0 27990.3125 0.160314302710216 0.337 0.4943 905 NINDS_000260 CO[C@@H]1[C@@H](OC(=O)N)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M23 mock treatment 1085170.0 -22100.0 -0.11 907680.0 -21900.0 -0.13 1087320.0 73590.3125 0.421487957116035 0.1058 0.2331 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 M24 mock treatment 979330.0 -128000.0 -0.63 978210.0 48600.0 0.29 946930.0 -66799.6875 -0.382594703893458 -0.4148 -0.5265 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N01 mock treatment 1137060.0 29800.0 0.15 949220.0 19600.0 0.12 963100.0 -50629.6875 -0.289981151442974 -0.0159 -0.0462 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N02 mock treatment 1197890.0 90600.0 0.44 908230.0 -21400.0 -0.13 1022650.0 8920.3125 0.0510910222383093 0.2119 0.4571 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N03 compound treatment 1266940.0 160000.0 0.78 961050.0 31500.0 0.19 1233350.0 219620.3125 1.25787367538098 1.2847 0.8611 906 NINDS_000261 N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N04 compound treatment 1385340.0 278000.0 1.36 991170.0 61600.0 0.37 1085200.0 71470.3125 0.409345673183133 1.2322 0.8408 907 NINDS_000262 OC(=O)c1cc(O)c2cccc(O)c2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N05 compound treatment 1241840.0 135000.0 0.66 1109890.0 180000.0 1.07 1108160.0 94430.3125 0.540848899173431 1.3109 0.9575 3173595 NINDS_000263 C[C@H]1OC(OC/2CC3O[C@@](O)(CC(O)C3C(=O)O)CC(O)C(O)CCC(O)CC(O)CC(O)CC(=O)O[C@@H](C)C(C)[C@H](O)[C@@H](C)/C=C/C=C/CC\C=C\C=C\C=C\C=C2)[C@@H](O)[C@@H](N)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N06 compound treatment 1152560.0 45300.0 0.22 1010080.0 80500.0 0.48 1007520.0 -6209.6875 -0.0355659380941476 0.3836 0.7258 3045298 NINDS_000264 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N07 compound treatment 1151290.0 44000.0 0.22 1026400.0 96800.0 0.58 1043040.0 29310.3125 0.167874592706174 0.5535 0.8688 909 NINDS_000265 COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N08 compound treatment 44980.0 -1060000.0 -5.19 55010.0 -875000.0 -5.2 53460.0 -960269.6875 -5.49993735744536 -9.1745 -0.9996 910 NINDS_000266 CN1CC(CNC(=O)OCc2ccccc2)C[C@@H]3C1Cc4cn(C)c5cccc3c45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N09 compound treatment 1231810.0 125000.0 0.61 1000230.0 70600.0 0.42 1036580.0 22850.3125 0.13087499166535 0.6695 0.8915 911 NINDS_000267 CCCCCC(C)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N10 compound treatment 1195710.0 88500.0 0.43 898100.0 -31500.0 -0.19 994920.0 -18809.6875 -0.107732342601019 0.0792 0.164 912 NINDS_000268 CCCc1cc(=O)[nH]c(=S)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N11 compound treatment 1217200.0 110000.0 0.54 905080.0 -24500.0 -0.15 968170.0 -45559.6875 -0.26094276486759 0.0754 0.1226 913 NINDS_000269 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)O)n2ccc(=O)[nH]c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N12 compound treatment 1432360.0 325000.0 1.59 952020.0 22400.0 0.13 1120640.0 106910.3125 0.61232800458976 1.3476 0.7892 914 NINDS_000270 OC[C@H]1O[C@@H](OC2c3cccc(O)c3C(=O)c4c(O)cc(CO)cc24)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N13 compound treatment 1411740.0 304000.0 1.49 1017510.0 87900.0 0.52 1101020.0 87290.3125 0.499954603286204 1.4494 0.8762 2797 NINDS_000271 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N14 compound treatment 1348880.0 242000.0 1.18 920590.0 -8990.0 -0.05 1049130.0 35400.3125 0.202755021551162 0.7678 0.6403 915 NINDS_000272 OC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N15 compound treatment 1238560.0 131000.0 0.64 1001440.0 71900.0 0.43 1040000.0 26270.3125 0.150463015745786 0.704 0.8964 471 NINDS_000273 CCCC(CCC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N16 compound treatment 1184410.0 77200.0 0.38 936520.0 6940.0 0.04 1110720.0 96990.3125 0.555511279771652 0.5622 0.8358 917 NINDS_000274 NS(=O)(=O)c1cc2c(NC(Cc3ccccc3)NS2(=O)=O)cc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N17 compound treatment 1309440.0 202000.0 0.99 914610.0 -15000.0 -0.09 1033940.0 20210.3125 0.115754411673434 0.5858 0.5866 918 NINDS_000275 CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N18 compound treatment 1301440.0 194000.0 0.95 945380.0 15800.0 0.09 1057280.0 43550.3125 0.249434084783781 0.746 0.757 919 NINDS_000276 COc1cc(ccc1c2nc3cccnc3[nH]2)S(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N19 compound treatment 1251200.0 144000.0 0.7 923970.0 -5610.0 -0.03 1046240.0 32510.3125 0.186202568453951 0.4943 0.6787 112 NINDS_000277 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N20 compound treatment 1296280.0 189000.0 0.92 906750.0 -22800.0 -0.14 1044710.0 30980.3125 0.177439505049545 0.5573 0.5865 920 NINDS_000278 CCN1CCCC1CNC(=O)c2cc(ccc2OC)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N21 compound treatment 1286210.0 179000.0 0.87 967330.0 37700.0 0.22 1081300.0 67570.3125 0.38700845274053 0.8578 0.8734 921 NINDS_000279 NCCCC(N)CC(=O)NCC1NC(=O)C(CO)NC(=O)C(N)CNC(=O)C(NC(=O)/C(=C/NC(=O)N)/NC1=O)C2CCNC(=N)N2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N22 compound treatment 928090.0 -179000.0 -0.88 752060.0 -178000.0 -1.06 860160.0 -153569.6875 -0.879569221279267 -1.6227 -0.996 922 NINDS_000280 CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N23 mock treatment 1204450.0 97200.0 0.47 957030.0 27400.0 0.16 1070300.0 56570.3125 0.324006036107547 0.5555 0.9295 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 N24 mock treatment 1075270.0 -32000.0 -0.16 961920.0 32300.0 0.19 975840.0 -37889.6875 -0.217012897997137 -0.1045 -0.3173 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O01 mock treatment 1184980.0 77700.0 0.38 823780.0 -106000.0 -0.63 979460.0 -34269.6875 -0.196279375432465 -0.2573 -0.3383 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O02 mock treatment 1357460.0 250000.0 1.22 1060000.0 130000.0 0.78 1131840.0 118110.3125 0.676475919706979 1.5441 0.9663 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O03 compound treatment 1270560.0 163000.0 0.8 1027330.0 97700.0 0.58 1096090.0 82360.3125 0.471718065649786 1.0686 0.9767 923 NINDS_000281 NC(=O)NC1NC(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O04 compound treatment 1325220.0 218000.0 1.06 949030.0 19400.0 0.12 1009500.0 -4229.6875 -0.0242255031002108 0.6676 0.6231 924 NINDS_000282 NC(=N)NC(=N)Nc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O05 compound treatment 1234720.0 127000.0 0.62 974160.0 44600.0 0.27 1044320.0 30590.3125 0.175205783005285 0.6138 0.8779 925 NINDS_000283 C[C@@H]([C@H](O)c1ccccc1)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O06 compound treatment 1123790.0 16500.0 0.08 941830.0 12200.0 0.07 872100.0 -141629.6875 -0.811182961770375 -0.3796 -0.4639 926 NINDS_000284 Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O07 compound treatment 412010.0 -695000.0 -3.4 376980.0 -553000.0 -3.29 402280.0 -611449.6875 -3.50207345108927 -5.8803 -0.9997 927 NINDS_000285 CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O08 compound treatment 32920.0 -1070000.0 -5.25 45130.0 -884000.0 -5.26 39040.0 -974689.6875 -5.58252779815878 -9.2901 -0.9996 928 NINDS_000286 CC(=O)O[Hg]c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O09 compound treatment 1394720.0 287000.0 1.4 999130.0 69500.0 0.41 997940.0 -15789.6875 -0.0904353154890542 0.9974 0.68 3173600 NINDS_000287 Oc1ccc2C[C@H]3N(CC=C)CC[C@]4(C5Oc1c24)[C@@]3(O)CCC5=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O10 compound treatment 1217210.0 110000.0 0.54 995300.0 65700.0 0.39 874490.0 -139239.6875 -0.797494254883754 0.0754 0.0726 930 NINDS_000288 CC(CN1CCCCC1)C(=O)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O11 compound treatment 1465030.0 358000.0 1.75 961150.0 31600.0 0.19 1072320.0 58590.3125 0.335575570798331 1.3113 0.7327 931 NINDS_000289 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O12 compound treatment 1353670.0 246000.0 1.2 1036930.0 107000.0 0.64 1033120.0 19390.3125 0.111057867888066 1.1278 0.8249 932 NINDS_000290 NCCCCC(N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O13 compound treatment 1333630.0 226000.0 1.11 853820.0 -75800.0 -0.45 955680.0 -58049.6875 -0.332479145208131 0.1865 0.1504 933 NINDS_000291 CN1C2C[C@@H](C[C@H]1[C@H]3OC32)OC(=O)[C@H](CO)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O14 compound treatment 357400.0 -750000.0 -3.66 348740.0 -581000.0 -3.45 354090.0 -659639.6875 -3.77808131086595 -6.2907 -0.9993 1001531 NINDS_000292 COc1cc(cc(OC)c1OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](O)c4cc5OCOc5cc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O15 compound treatment 1251430.0 144000.0 0.7 882650.0 -46900.0 -0.28 988040.0 -25689.6875 -0.147137490458739 0.1606 0.2081 934 NINDS_000293 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O16 compound treatment 1268810.0 162000.0 0.79 1034250.0 105000.0 0.62 1094440.0 80710.3125 0.462267703154838 1.082 0.9779 935 NINDS_000294 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O17 compound treatment 921300.0 -186000.0 -0.91 712420.0 -217000.0 -1.29 761350.0 -252379.6875 -1.44550274741609 -2.1047 -0.9832 936 NINDS_000295 OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O18 compound treatment 692320.0 -415000.0 -2.03 591740.0 -338000.0 -2.01 593450.0 -420279.6875 -2.40714872493225 -3.7201 -0.9964 937 NINDS_000296 CCC(=O)c1ccc2Sc3ccccc3N(CC(C)N(C)C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O19 compound treatment 1237760.0 131000.0 0.64 856090.0 -73500.0 -0.44 938370.0 -75359.6875 -0.431622039018761 -0.1334 -0.1507 938 NINDS_000297 Cc1ccc(cc1)/C(=C\CN2CCCC2)/c3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O20 compound treatment 1181050.0 73800.0 0.36 884550.0 -45000.0 -0.27 988660.0 -25069.6875 -0.143586445157607 -0.0293 -0.0622 939 NINDS_000298 Cc1cccc(Nc2ccccc2C(=O)O)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O21 compound treatment 1268700.0 161000.0 0.79 864890.0 -64700.0 -0.38 937520.0 -76209.6875 -0.436490407576764 -0.0187 -0.0191 940 NINDS_000299 CC(C)CC1NC(=O)CNC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O22 compound treatment 1188540.0 81300.0 0.4 870780.0 -58800.0 -0.35 989120.0 -24609.6875 -0.140951798643864 -0.054 -0.0986 941 NINDS_000300 CC(=O)Oc1cccc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O23 mock treatment 1266720.0 159000.0 0.78 954910.0 25300.0 0.15 1053500.0 39770.3125 0.227784163431719 0.6683 0.8095 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 O24 mock treatment 1080230.0 -27000.0 -0.13 994970.0 65400.0 0.39 963150.0 -50579.6875 -0.289694776821915 -0.019 -0.0378 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P01 mock treatment 972480.0 -135000.0 -0.66 847040.0 -82500.0 -0.49 862830.0 -150899.6875 -0.864276816514715 -1.1626 -0.9751 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P02 mock treatment 1140190.0 32900.0 0.16 988060.0 58500.0 0.35 1122990.0 109260.3125 0.625787611779534 0.655 0.8926 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P03 compound treatment 1106830.0 -423.0 0.0 829560.0 -100000.0 -0.59 960130.0 -53599.6875 -0.306991803933879 -0.5218 -0.7796 942 NINDS_000301 OC(=O)c1ccccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P04 compound treatment 69650.0 -1040000.0 -5.07 63580.0 -866000.0 -5.15 56480.0 -957249.6875 -5.4826403303334 -9.0655 -0.9994 943 NINDS_000302 CCCCC1C(=O)N(N(C1=O)c2ccc(O)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P05 compound treatment 1096710.0 -10500.0 -0.05 1006360.0 76800.0 0.46 997960.0 -15769.6875 -0.0903207656406306 0.1817 0.3881 944 NINDS_000303 Nc1ccc(cc1)S(=O)(=O)Nc2ccnn2c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P06 compound treatment 1175900.0 68600.0 0.34 965330.0 35700.0 0.21 913570.0 -100159.6875 -0.573663851064031 -0.0148 -0.0213 945 NINDS_000304 C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P07 compound treatment 1130790.0 23500.0 0.11 880020.0 -49600.0 -0.29 1022080.0 8350.3125 0.0478263515582366 -0.0762 -0.238 946 NINDS_000305 OCCNC(=O)Cn1ccnc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P08 compound treatment 1172280.0 65000.0 0.32 974310.0 44700.0 0.27 1079470.0 65740.3125 0.37652714160977 0.5544 0.9902 3173722 NINDS_000306 NCC[C@@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)C3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P09 compound treatment 1332380.0 225000.0 1.1 980350.0 50800.0 0.3 958610.0 -55119.6875 -0.315697592414073 0.6271 0.5298 948 NINDS_000307 O=C1C(C(=O)c2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P10 compound treatment 1144400.0 37100.0 0.18 992390.0 62800.0 0.37 899680.0 -114049.6875 -0.653218720794224 -0.0567 -0.0733 465 NINDS_000308 NCCc1c[nH]cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P11 compound treatment 1158940.0 51700.0 0.25 1013390.0 83800.0 0.5 939420.0 -74309.6875 -0.425608171976521 0.1878 0.2674 949 NINDS_000309 OC(=O)c1cc(O)c2ccccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P12 compound treatment 1048030.0 -59200.0 -0.29 860320.0 -69300.0 -0.41 862240.0 -151489.6875 -0.867656037043212 -0.9058 -0.903 950 NINDS_000310 Oc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P13 compound treatment 932830.0 -174000.0 -0.85 839590.0 -90000.0 -0.54 1060580.0 46850.3125 0.268334809773676 -0.6461 -0.6203 1000111 NINDS_000311 OC(=O)CCCCC1SCC2NC(=O)NC12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P14 compound treatment 827390.0 -280000.0 -1.37 784590.0 -145000.0 -0.86 731840.0 -281889.6875 -1.61452104876511 -2.2194 -0.9714 3256 NINDS_000312 CCN(CCCc1ccccc1)CCCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P15 compound treatment 117920.0 -989000.0 -4.83 203680.0 -726000.0 -4.32 104650.0 -909079.6875 -5.20674702040514 -8.2891 -0.9971 110 NINDS_000313 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P16 compound treatment 1073170.0 -34100.0 -0.17 898730.0 -30900.0 -0.18 1026890.0 13160.3125 0.0753755901041135 -0.1586 -0.6122 952 NINDS_000314 CC(C)(S)[C@@H](N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P17 compound treatment 935710.0 -172000.0 -0.84 690110.0 -239000.0 -1.42 770040.0 -243689.6875 -1.39573083827603 -2.1119 -0.9764 953 NINDS_000315 C[C@H](N)[C@H](O)c1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P18 compound treatment 1213280.0 106000.0 0.52 946240.0 16700.0 0.1 1050020.0 36290.3125 0.207852489806012 0.4763 0.8401 954 NINDS_000316 CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P19 compound treatment 1344590.0 237000.0 1.16 978180.0 48600.0 0.29 945380.0 -68349.6875 -0.391472317146287 0.6103 0.4853 955 NINDS_000317 CCN(CC)CCNC(=O)c1cc(Br)c(N)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P20 compound treatment 1230240.0 123000.0 0.6 948160.0 18600.0 0.11 1044920.0 31190.3125 0.178642278457993 0.5138 0.8072 956 NINDS_000318 CCn1nc(C(=O)O)c(=O)c2cc3OCOc3cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P21 compound treatment 255090.0 -852000.0 -4.16 206830.0 -723000.0 -4.3 236530.0 -777199.6875 -4.4514053198999 -7.4552 -0.9996 957 NINDS_000319 NC(COC(=O)C=[N+]=[N-])C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P22 compound treatment 1005010.0 -102000.0 -0.5 859360.0 -70200.0 -0.42 1052230.0 38500.3125 0.220510248056821 -0.4022 -0.5851 958 NINDS_000320 NC(=O)NC(=O)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P23 mock treatment 1077280.0 -30000.0 -0.15 959460.0 29900.0 0.18 1056360.0 42630.3125 0.244164791756295 0.159 0.4738 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.500 P24 mock treatment 948130.0 -159000.0 -0.78 909410.0 -20200.0 -0.12 873300.0 -140429.6875 -0.804309970864958 -0.9825 -0.8733 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A01 mock treatment 927250.0 -163000.0 -0.79 909540.0 -171000.0 -1.02 830190.0 -147689.21875 -0.845888881080655 -1.536 -0.9942 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A02 mock treatment 878250.0 -212000.0 -1.03 950480.0 -131000.0 -0.78 853830.0 -124049.21875 -0.710490960243954 -1.4554 -0.9865 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A03 compound treatment 859140.0 -231000.0 -1.13 801610.0 -279000.0 -1.66 801450.0 -176429.21875 -1.01049701326537 -2.1937 -0.9759 959 NINDS_000321 COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A04 compound treatment 958250.0 -132000.0 -0.64 925020.0 -156000.0 -0.93 856770.0 -121109.21875 -0.693652132525684 -1.3075 -0.9868 960 NINDS_000322 C1N2CN3CN1CN(C2)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A05 compound treatment 857350.0 -233000.0 -1.14 799140.0 -282000.0 -1.68 789280.0 -188599.21875 -1.08020059603114 -2.2474 -0.9792 3173724 NINDS_000323 COc1ccc2C(OC(=O)c2c1OC)[C@@H]3N(C)CCc4cc5OCOc5c(OC)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A06 compound treatment 943520.0 -146000.0 -0.72 943440.0 -138000.0 -0.82 967690.0 -10189.21875 -0.0583586731683725 -0.919 -0.8445 962 NINDS_000324 CCC1(C(=O)NCNC1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A07 compound treatment 950530.0 -139000.0 -0.68 1000520.0 -80500.0 -0.48 976430.0 -1449.21875 -0.00830038940725729 -0.6743 -0.8101 3173725 NINDS_000325 CCN1CCN(C(=O)NC(C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4)C(=O)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A08 compound treatment 843280.0 -247000.0 -1.21 863210.0 -218000.0 -1.3 833760.0 -144119.21875 -0.825441733137041 -1.9201 -0.9836 964 NINDS_000326 CN(C)N=Nc1[nH]cnc1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A09 compound treatment 1020750.0 -69200.0 -0.34 78830.0 -1000000.0 -5.96 950160.0 -27719.21875 -0.158761615311662 -3.7275 -0.6242 3173726 NINDS_000327 NNC(=O)c1ccncc1.Nc1ccc(C(=O)O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A10 compound treatment 973240.0 -117000.0 -0.57 930240.0 -151000.0 -0.9 1027430.0 49550.78125 0.283801724072935 -0.6829 -0.621 965 NINDS_000328 C(C1=NCCN1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A11 compound treatment 937280.0 -153000.0 -0.75 905640.0 -175000.0 -1.04 901080.0 -76799.21875 -0.439866943343188 -1.2866 -0.9492 966 NINDS_000329 OC[C@@H]1OC(=O)[C@@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A12 compound treatment 847620.0 -242000.0 -1.18 825130.0 -256000.0 -1.52 846880.0 -130999.21875 -0.750297032571156 -1.9952 -0.9644 967 NINDS_000330 C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)/C=C/C=C(\C)/C=C/C2=C(C)CCCC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A13 compound treatment 945640.0 -144000.0 -0.7 976120.0 -105000.0 -0.62 956900.0 -20979.21875 -0.120158316392907 -0.8365 -0.8815 968 NINDS_000331 CCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A14 compound treatment 632200.0 -458000.0 -2.24 497360.0 -584000.0 -3.47 549770.0 -428109.21875 -2.45199230582802 -4.7106 -0.981 969 NINDS_000332 CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A15 compound treatment 979480.0 -110000.0 -0.54 920480.0 -161000.0 -0.95 937810.0 -40069.21875 -0.229496146713238 -0.9952 -0.8883 970 NINDS_000333 CC1(C)O[C@]2(C)CC[C@H]1CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A16 compound treatment 924850.0 -165000.0 -0.81 944500.0 -137000.0 -0.81 957870.0 -20009.21875 -0.114602648744362 -1.0005 -0.87 971 NINDS_000334 CN(C(=S)Oc1ccc2ccccc2c1)c3cccc(C)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A17 compound treatment 128860.0 -961000.0 -4.7 72560.0 -1010000.0 -6.0 82500.0 -895379.21875 -5.1282776894729 -9.1341 -0.9948 972 NINDS_000335 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3/C(=C\CCN4CCN(C)CC4)/c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A18 compound treatment 922290.0 -168000.0 -0.82 819200.0 -262000.0 -1.56 915740.0 -62139.21875 -0.355901904448686 -1.5772 -0.8788 973 NINDS_000336 COc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A19 compound treatment 796050.0 -294000.0 -1.44 767800.0 -313000.0 -1.86 827150.0 -150729.21875 -0.863300458041042 -2.4027 -0.9591 1000112 NINDS_000337 CC(=O)O[C@H]1[C@@H](O)C2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A20 compound treatment 854880.0 -235000.0 -1.15 814590.0 -266000.0 -1.58 832540.0 -145339.21875 -0.832429273890881 -2.0583 -0.968 975 NINDS_000338 CCN(CC)CCOC(=O)C(CC1CCCO1)Cc2cccc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A21 compound treatment 716930.0 -373000.0 -1.82 747260.0 -334000.0 -1.98 770890.0 -206989.21875 -1.18552918165664 -2.8825 -0.9792 3173729 NINDS_000339 CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1.OC(=O)c1ccccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A22 compound treatment 828180.0 -262000.0 -1.28 807740.0 -273000.0 -1.63 892520.0 -85359.21875 -0.488894278468491 -1.9588 -0.9218 977 NINDS_000340 C[C@@]12C[C@H](O)[C@@]3(F)C(CCC4=CC(=O)C=C[C@@]43C)C2C[C@@H](O)[C@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A23 mock treatment 987900.0 -102000.0 -0.5 867770.0 -213000.0 -1.27 1024240.0 46360.78125 0.26553102324937 -0.8666 -0.6243 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 A24 mock treatment 937970.0 -152000.0 -0.74 788480.0 -293000.0 -1.74 866520.0 -111359.21875 -0.637809081419177 -1.8012 -0.9024 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B01 mock treatment 1077680.0 -12200.0 -0.06 958920.0 -122000.0 -0.73 939700.0 -38179.21875 -0.218671186037207 -0.58 -0.7625 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B02 mock treatment 966300.0 -124000.0 -0.6 1022340.0 -58700.0 -0.35 884330.0 -93549.21875 -0.535802441397957 -0.8595 -0.9772 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B03 compound treatment 1050000.0 -39900.0 -0.2 962940.0 -118000.0 -0.7 907080.0 -70799.21875 -0.405501988816106 -0.7521 -0.9019 198 NINDS_000341 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B04 compound treatment 1050560.0 -39400.0 -0.19 970760.0 -110000.0 -0.66 909820.0 -68059.21875 -0.389808659582073 -0.7146 -0.9085 978 NINDS_000342 COC(=O)C(C)C[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B05 compound treatment 793010.0 -297000.0 -1.45 696000.0 -385000.0 -2.29 665980.0 -311899.21875 -1.78640041156266 -3.1908 -0.9829 417 NINDS_000343 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B06 compound treatment 59010.0 -1030000.0 -5.04 30320.0 -1050000.0 -6.25 46270.0 -931609.21875 -5.33578473989226 -9.5959 -0.9957 3045266 NINDS_000344 S=C1CC=CC=[N+]1O[Zn]On2ccccc2=S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B07 compound treatment 917630.0 -172000.0 -0.84 946780.0 -134000.0 -0.8 938880.0 -38999.21875 -0.223367729822575 -1.0758 -0.9106 980 NINDS_000345 C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=C(C(=O)N)C(=O)[C@@]3(O)C(=C2C(=O)c4c(O)cccc14)O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B08 compound treatment 67230.0 -1020000.0 -5.0 43740.0 -1040000.0 -6.17 57640.0 -920239.21875 -5.27066315106344 -9.4891 -0.9959 981 NINDS_000346 CCCCCCCCCCCCCCCC[n+]1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B09 compound treatment 939170.0 -151000.0 -0.74 977280.0 -104000.0 -0.62 911650.0 -66229.21875 -0.379327348451313 -1.0004 -0.9685 982 NINDS_000347 CC(=O)Oc1ccc(cc1)C(c2ccc(OC(=O)C)cc2)c3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B10 compound treatment 989010.0 -101000.0 -0.49 920960.0 -160000.0 -0.95 959320.0 -18559.21875 -0.106297784733651 -0.8955 -0.8314 983 NINDS_000348 NCCCS(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B11 compound treatment 890780.0 -199000.0 -0.97 883540.0 -197000.0 -1.17 1005570.0 27690.78125 0.158598739745935 -1.1482 -0.7488 984 NINDS_000349 C[C@H]1CC2C3CC[C@H](C(=O)C)[C@@]3(C)C[C@H](O)C2[C@@]4(C)CCC(=O)C=C14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B12 compound treatment 1057440.0 -32500.0 -0.16 1083280.0 2270.0 0.01 941530.0 -36349.21875 -0.208189874906447 -0.204 -0.7784 985 NINDS_000350 Nc1ccc(C(=O)O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B13 compound treatment 1073560.0 -16400.0 -0.08 1106080.0 25100.0 0.15 1090990.0 113110.78125 0.64784114236315 0.4139 0.6182 986 NINDS_000351 CN1CC(=O)NC1=N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B14 compound treatment 983430.0 -106000.0 -0.52 1010240.0 -70800.0 -0.42 1007290.0 29410.78125 0.168450026710365 -0.4461 -0.6465 987 NINDS_000352 CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B15 compound treatment 948640.0 -141000.0 -0.69 962150.0 -119000.0 -0.71 925310.0 -52569.21875 -0.301089801977991 -0.9805 -0.9493 988 NINDS_000353 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B16 compound treatment 677950.0 -412000.0 -2.01 560650.0 -520000.0 -3.09 667380.0 -310499.21875 -1.77838192217301 -3.9754 -0.9702 446 NINDS_000354 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B17 compound treatment 963680.0 -126000.0 -0.62 954680.0 -126000.0 -0.75 938360.0 -39519.21875 -0.226346025881589 -0.9205 -0.9223 989 NINDS_000355 NC(=N)NCCCCNC(=N)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B18 compound treatment 781970.0 -308000.0 -1.5 748650.0 -332000.0 -1.98 742970.0 -234909.21875 -1.34544077005599 -2.7866 -0.9864 990 NINDS_000356 CCN(CC)CCOCCOC(=O)C1(CCCC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B19 compound treatment 1005090.0 -84800.0 -0.41 974180.0 -107000.0 -0.64 1053390.0 75510.78125 0.432487427326773 -0.3564 -0.4082 991 NINDS_000357 CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B20 compound treatment 1057460.0 -32500.0 -0.16 1001630.0 -79400.0 -0.47 978190.0 310.78125 0.00177999725401992 -0.3631 -0.7291 992 NINDS_000358 CC[C@H]1[C@@H](Cc2cncn2C)COC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B21 compound treatment 1011590.0 -78300.0 -0.38 917620.0 -163000.0 -0.97 933940.0 -43939.21875 -0.251661542383205 -0.9272 -0.8632 993 NINDS_000359 CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B22 compound treatment 980580.0 -109000.0 -0.53 998560.0 -82500.0 -0.49 958910.0 -18969.21875 -0.108646056626335 -0.6542 -0.8923 994 NINDS_000360 N[C@@H](CCONC(=N)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B23 mock treatment 938320.0 -152000.0 -0.74 1026770.0 -54200.0 -0.32 969700.0 -8179.21875 -0.0468464134018003 -0.6409 -0.792 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 B24 mock treatment 938660.0 -151000.0 -0.74 994500.0 -86500.0 -0.51 1037060.0 59180.78125 0.3389574760889 -0.528 -0.5488 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C01 mock treatment 1068070.0 -21900.0 -0.11 993440.0 -87600.0 -0.52 1035740.0 57860.78125 0.331397186092942 -0.171 -0.2729 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C02 mock treatment 1025460.0 -64500.0 -0.31 1020240.0 -60800.0 -0.36 884000.0 -93879.21875 -0.537692513896946 -0.7009 -0.973 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C03 compound treatment 1015370.0 -74600.0 -0.36 985720.0 -95300.0 -0.57 917930.0 -59949.21875 -0.343358696046301 -0.7357 -0.973 995 NINDS_000361 CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@@H]([C@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C04 compound treatment 669200.0 -421000.0 -2.06 667740.0 -413000.0 -2.46 631640.0 -346239.21875 -1.98308250130599 -3.7506 -0.9954 996 NINDS_000362 NCCc1cc(O)c(O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C05 compound treatment 1018110.0 -71800.0 -0.35 981940.0 -99100.0 -0.59 903360.0 -74519.21875 -0.426808260622897 -0.7891 -0.977 997 NINDS_000363 NCc1ccc(cc1)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C06 compound treatment 673370.0 -417000.0 -2.04 49780.0 -1030000.0 -6.13 449070.0 -528809.21875 -3.02875079264086 -6.4642 -0.9059 998 NINDS_000364 CCCCCCCCNC(C)C(O)c1ccc(SC(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C07 compound treatment 989410.0 -101000.0 -0.49 1006880.0 -74100.0 -0.44 946120.0 -31759.21875 -0.18190068469323 -0.6431 -0.9394 999 NINDS_000365 CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C08 compound treatment 935890.0 -154000.0 -0.75 922970.0 -158000.0 -0.94 881760.0 -96119.21875 -0.55052209692039 -1.2949 -0.9781 1000 NINDS_000366 NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C09 compound treatment 1167710.0 77800.0 0.38 1035530.0 -45500.0 -0.27 1133510.0 155630.78125 0.891374120111734 0.5779 0.5744 1001 NINDS_000367 CN(C)CCOC(=O)COc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C10 compound treatment 929460.0 -160000.0 -0.78 861030.0 -220000.0 -1.31 918940.0 -58939.21875 -0.337573928700909 -1.4028 -0.8981 1002 NINDS_000368 CN(C)CCOC(c1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C11 compound treatment 1044290.0 -45600.0 -0.22 1009640.0 -71400.0 -0.42 922930.0 -54949.21875 -0.3147212339404 -0.5555 -0.9686 347 NINDS_000369 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C12 compound treatment 955840.0 -134000.0 -0.66 1010180.0 -70800.0 -0.42 1144210.0 166330.78125 0.952658289018362 -0.0714 -0.058 3173852 NINDS_000370 COc1ccc(CCC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO)C(O)[C@H](O)C3O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)cc2O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C13 compound treatment 429180.0 -661000.0 -3.23 358840.0 -722000.0 -4.29 398350.0 -579529.21875 -3.31924920824313 -6.2596 -0.9912 1004 NINDS_000371 Oc1ccc2c(=O)cc(oc2c1O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C14 compound treatment 891480.0 -198000.0 -0.97 795520.0 -285000.0 -1.7 792010.0 -185869.21875 -1.06456454172132 -2.1546 -0.9679 1005 NINDS_000372 OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C15 compound treatment 403610.0 -686000.0 -3.35 355560.0 -725000.0 -4.31 334340.0 -643539.21875 -3.68586599812287 -6.5547 -0.9945 1006 NINDS_000373 Nc1ccn(C2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C16 compound treatment 1102720.0 12800.0 0.06 1056230.0 -24800.0 -0.15 1035480.0 57600.78125 0.329908038063435 0.1415 0.3858 1000113 NINDS_000374 CC1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)C(O)CC2(C)[C@@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C17 compound treatment 214720.0 -875000.0 -4.28 197570.0 -883000.0 -5.25 203220.0 -774659.21875 -4.43685480438802 -8.0635 -0.9958 349 NINDS_000375 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C18 compound treatment 1021760.0 -68200.0 -0.33 965920.0 -115000.0 -0.68 927760.0 -50119.21875 -0.287057445546099 -0.7532 -0.9259 1008 NINDS_000376 OC1CCCCC1N2CCC(CC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C19 compound treatment 1086690.0 -3230.0 -0.02 968960.0 -112000.0 -0.67 1075330.0 97450.78125 0.558148611047468 -0.0716 -0.0823 1009 NINDS_000377 C[N+]1(C)C2CC(CC1C3OC32)OC(=O)[C@@H](CO)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C20 compound treatment 973920.0 -116000.0 -0.57 993800.0 -87200.0 -0.52 1131360.0 153480.78125 0.879060011406196 -0.1191 -0.102 1010 NINDS_000378 COc1ccc(CN(CCN(C)C)c2ncccn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C21 compound treatment 1021330.0 -68600.0 -0.34 997920.0 -83100.0 -0.49 1096260.0 118380.78125 0.67802502742277 -0.0873 -0.0966 1011 NINDS_000379 C[N+](C)(C)CC#CCN1CCCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C22 compound treatment 1028540.0 -61400.0 -0.3 1026720.0 -54300.0 -0.32 1046450.0 68570.78125 0.392738629923783 -0.1328 -0.225 1012 NINDS_000380 Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C23 mock treatment 992450.0 -97500.0 -0.48 988640.0 -92400.0 -0.55 986110.0 8230.78125 0.0471417372297674 -0.5649 -0.7754 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 C24 mock treatment 898800.0 -191000.0 -0.93 944120.0 -137000.0 -0.81 904660.0 -73219.21875 -0.419362520475363 -1.2512 -0.9567 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D01 mock treatment 1080160.0 -9760.0 -0.05 1104520.0 23500.0 0.14 990990.0 13110.78125 0.0750919002451269 0.0965 0.5825 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D02 mock treatment 1057060.0 -32900.0 -0.16 1053090.0 -27900.0 -0.17 978600.0 720.78125 0.00412826914670381 -0.1862 -0.8059 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D03 compound treatment 1089480.0 -444.0 0.0 1011900.0 -69100.0 -0.41 1008900.0 31020.78125 0.177671289508465 -0.136 -0.3036 1013 NINDS_000381 Cc1ccc(O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D04 compound treatment 909760.0 -180000.0 -0.88 915900.0 -165000.0 -0.98 842330.0 -135549.21875 -0.776357123087526 -1.5233 -0.9955 3173855 NINDS_000382 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)/C(=N\OCOCCOC)/[C@H](C)[C@@H](O)[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D05 compound treatment 1051840.0 -38100.0 -0.19 1001360.0 -79700.0 -0.47 961710.0 -16169.21875 -0.0926090778470303 -0.4344 -0.8397 3471725 NINDS_000383 CC1(C)SC2C(NC(=O)C(N=C)c3ccccc3)C(=O)N2C1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D06 compound treatment 994430.0 -95500.0 -0.47 991860.0 -89200.0 -0.53 917600.0 -60279.21875 -0.34524876854529 -0.7748 -0.9856 1016 NINDS_000384 CN1CCOC(c2ccccc2)c3ccccc3C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D07 compound treatment 1130930.0 41000.0 0.2 990620.0 -90400.0 -0.54 983520.0 5640.78125 0.0323075318589106 -0.176 -0.3063 1017 NINDS_000385 CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D08 compound treatment 371940.0 -718000.0 -3.51 211850.0 -869000.0 -5.17 267320.0 -710559.21875 -4.06972254019037 -7.359 -0.9871 2117626 NINDS_000386 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D09 compound treatment 793120.0 -297000.0 -1.45 758240.0 -323000.0 -1.92 862580.0 -115299.21875 -0.660375401558627 -2.3267 -0.9327 1018 NINDS_000387 COc1ccc2C[C@H]3[C@@H]4CCCC[C@@]4(CCN3C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D10 compound treatment 946940.0 -143000.0 -0.7 886740.0 -194000.0 -1.16 948870.0 -29009.21875 -0.166150080534985 -1.1662 -0.8574 1019 NINDS_000388 NC(=O)N1c2ccccc2C=Cc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D11 compound treatment 765470.0 -324000.0 -1.59 737720.0 -343000.0 -2.04 850010.0 -127869.21875 -0.732369981292862 -2.5167 -0.9368 3173857 NINDS_000389 NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(=N)N)cc1.OCCS(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D12 compound treatment 1109780.0 19900.0 0.1 1030140.0 -50900.0 -0.3 1063250.0 85370.78125 0.48896050259961 0.1637 0.2807 1021 NINDS_000390 CO[C@@H]1[C@@H](O)[C@H](C)O[C@@H](O[C@H]2CC[C@@]3(C)[C@H](CCC4C3CC[C@]5(C)C(CC[C@]45O)C6=CC(=O)OC6)C2)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D13 compound treatment 857810.0 -232000.0 -1.13 1182770.0 102000.0 0.61 886910.0 -90969.21875 -0.521025510951312 -0.6062 -0.4371 1022 NINDS_000391 COc1cc(OC)c2ccc(=O)oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D14 compound treatment 951380.0 -139000.0 -0.68 936020.0 -145000.0 -0.86 929380.0 -48499.21875 -0.277778907823787 -1.049 -0.9276 1023 NINDS_000392 CN[C@H](CC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D15 compound treatment 925360.0 -165000.0 -0.8 855310.0 -226000.0 -1.34 838370.0 -139509.21875 -0.7990379930754 -1.7004 -0.9679 1024 NINDS_000393 c1ccc2c(c1)sc3ccccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D16 compound treatment 995840.0 -94100.0 -0.46 967300.0 -114000.0 -0.68 1165010.0 187130.78125 1.07179013137891 -0.037 -0.0274 3173859 NINDS_000394 CC(C)CC(=O)OC1C(O[C@@H]2C[C@H]([C@H]3CC[C@]4(CC5CC[C@H]4[C@]3(C)C2)[C@@H](O)C5=C)C(=O)O)OC(CO)C(OS(=O)(=O)O)C1OS(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D17 compound treatment 999360.0 -90600.0 -0.44 1036290.0 -44700.0 -0.27 1266240.0 288360.78125 1.65158418917499 0.5445 0.3147 1026 NINDS_000395 CC(=O)NC(Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D18 compound treatment 1043870.0 -46100.0 -0.23 1037870.0 -43100.0 -0.26 1119420.0 141540.78125 0.810673751897304 0.19 0.216 3264 NINDS_000396 Cn1nnnc1SCC2=C(N3C(SC2)C(NC(=O)C(OC=O)c4ccccc4)C3=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D19 compound treatment 1077730.0 -12200.0 -0.06 1143390.0 62400.0 0.37 1061180.0 83300.78125 0.477104593287767 0.4552 0.7496 935 NINDS_000397 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D20 compound treatment 1067630.0 -22300.0 -0.11 946460.0 -135000.0 -0.8 906960.0 -70919.21875 -0.406189287906648 -0.7594 -0.8401 3173860 NINDS_000398 O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5OC1[C@]2(CCN3CC6CCC6)c54 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D21 compound treatment 815200.0 -275000.0 -1.34 796570.0 -284000.0 -1.69 840330.0 -137549.21875 -0.787812107929887 -2.2064 -0.9599 1000056 NINDS_000399 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D22 compound treatment 686320.0 -404000.0 -1.97 658240.0 -423000.0 -2.51 687620.0 -290259.21875 -1.66245747556832 -3.5498 -0.9856 1028 NINDS_000400 Oc1ccc(cc1)C(=C2C=CC(=O)C=C2)c3ccc(O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D23 mock treatment 1005200.0 -84700.0 -0.41 989220.0 -91800.0 -0.55 963060.0 -14819.21875 -0.084876963078437 -0.6031 -0.8737 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 D24 mock treatment 1031200.0 -58700.0 -0.29 1013610.0 -67400.0 -0.4 970670.0 -7209.21875 -0.0412907457532554 -0.4209 -0.8509 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E01 mock treatment 1089030.0 -894.0 0.0 1119250.0 38200.0 0.23 1107960.0 130080.78125 0.745036688750579 0.5589 0.7175 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E02 mock treatment 1091640.0 1720.0 0.01 1069700.0 -11300.0 -0.07 943050.0 -34829.21875 -0.199484086426253 -0.1492 -0.708 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E03 compound treatment 795790.0 -294000.0 -1.44 800250.0 -281000.0 -1.67 696320.0 -281559.21875 -1.61262829150405 -2.7247 -0.998 1029 NINDS_000401 CC(C(=O)O)c1ccc(cc1)N2Cc3ccccc3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E04 compound treatment 1054200.0 -35700.0 -0.17 1012800.0 -68200.0 -0.41 931240.0 -46639.21875 -0.267125771920392 -0.4892 -0.9479 915 NINDS_000402 OC(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E05 compound treatment 1048560.0 -41400.0 -0.2 983280.0 -97700.0 -0.58 933720.0 -44159.21875 -0.252921590715865 -0.5982 -0.8993 1031 NINDS_000403 COc1ccc(cc1)C(=O)N2CCCC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E06 compound treatment 977450.0 -112000.0 -0.55 1049030.0 -32000.0 -0.19 833480.0 -144399.21875 -0.827045431014972 -0.9046 -0.8947 1000114 NINDS_000404 CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E07 compound treatment 1095570.0 5650.0 0.03 1054790.0 -26200.0 -0.16 947900.0 -29979.21875 -0.171705748183529 -0.1732 -0.7417 1033 NINDS_000405 CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E08 compound treatment 1037300.0 -52600.0 -0.26 1004280.0 -76700.0 -0.46 973400.0 -4479.21875 -0.0256546914434334 -0.4267 -0.8137 1034 NINDS_000406 CC(=O)N[C@@H](CCC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E09 compound treatment 885530.0 -204000.0 -1.0 813890.0 -267000.0 -1.59 901380.0 -76499.21875 -0.438148695616834 -1.7466 -0.9065 1035 NINDS_000407 Cc1cccc(CN2CCN(CC2)C(c3ccccc3)c4ccc(Cl)cc4)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E10 compound treatment 1059920.0 -30000.0 -0.15 1096960.0 15900.0 0.09 1041000.0 63120.78125 0.36152379622835 0.1788 0.4455 1036 NINDS_000408 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E11 compound treatment 1164160.0 74200.0 0.36 1161650.0 80600.0 0.48 1205480.0 227600.78125 1.30358174966407 1.2389 0.863 1037 NINDS_000409 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E12 compound treatment 1396720.0 307000.0 1.5 1151360.0 70300.0 0.42 1087570.0 109690.78125 0.628253118282714 1.4697 0.8757 1038 NINDS_000410 O=C1CCCN1CC#CCN2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E13 compound treatment 1038210.0 -51700.0 -0.25 806280.0 -275000.0 -1.63 745450.0 -232429.21875 -1.33123658885147 -1.8577 -0.8752 1039 NINDS_000411 CC[C@]1(CCCN2CCc3c4[C@@H]21)CC(=O)n4c5ccccc35 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E14 compound treatment 44960.0 -1040000.0 -5.11 26880.0 -1050000.0 -6.27 38910.0 -938969.21875 -5.37793908411215 -9.6717 -0.9961 1040 NINDS_000412 CC(C)CC1NC(=O)C(CCCN)NC(=O)C(NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(Cc3ccccc3)NC(=O)C(Cc4ccccc4)NC(=O)C5CCCN5C(=O)C(Cc6ccccc6)NC1=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E15 compound treatment 52910.0 -1040000.0 -5.07 31850.0 -1050000.0 -6.24 47160.0 -930719.21875 -5.33068727163741 -9.605 -0.9959 1041 NINDS_000413 CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E16 compound treatment 880960.0 -209000.0 -1.02 988900.0 -92100.0 -0.55 1084490.0 106610.78125 0.610612441625479 -0.5532 -0.4224 1000115 NINDS_000414 COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E17 compound treatment 635570.0 -454000.0 -2.22 615470.0 -466000.0 -2.77 572830.0 -405049.21875 -2.3199163305956 -4.2194 -0.9952 1043 NINDS_000415 O[Hg]c1c(O)c(Br)cc2c(c3ccccc3C(=O)O)c4cc(Br)c(=O)cc4oc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E18 compound treatment 1086420.0 -3500.0 -0.02 1082110.0 1100.0 0.01 1138600.0 160720.78125 0.920527056535541 0.5254 0.5706 1044 NINDS_000416 C[C@H](CCC(=O)O)[C@H]1CCC2C3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E19 compound treatment 1099630.0 9710.0 0.05 1177030.0 96000.0 0.57 1055570.0 77690.78125 0.444973360804946 0.6139 0.8463 1045 NINDS_000417 C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E20 compound treatment 1091890.0 1970.0 0.01 1111890.0 30900.0 0.18 1096430.0 118550.78125 0.678998701134371 0.5036 0.7159 1046 NINDS_000418 CC1C2C(CC3C4CC[C@H]5C[C@@H](O)CC[C@]5(C)C4CC(=O)[C@]23C)OC61CCC(C)CO6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E21 compound treatment 658910.0 -431000.0 -2.11 681280.0 -400000.0 -2.38 694160.0 -283719.21875 -1.6249996751338 -3.5264 -0.9885 1047 NINDS_000419 CN(C)CCCN1c2ccccc2Sc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E22 compound treatment 1066530.0 -23400.0 -0.11 1076830.0 -4180.0 -0.02 1083950.0 106070.78125 0.607519595718041 0.2704 0.4371 1048 NINDS_000420 CCn1cc(C(=O)O)c(=O)c2cc(F)c(nc12)N3CCNCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E23 mock treatment 1101320.0 11400.0 0.06 1060700.0 -20300.0 -0.12 1024320.0 46440.78125 0.265989222643064 0.116 0.39 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 E24 mock treatment 1091920.0 2000.0 0.01 1151240.0 70200.0 0.42 1126940.0 149060.78125 0.853744494904579 0.7397 0.7782 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F01 mock treatment 1164770.0 74800.0 0.37 1067200.0 -13800.0 -0.08 873440.0 -104439.21875 -0.598174833864609 -0.1816 -0.2573 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F02 mock treatment 1118610.0 28700.0 0.14 1093830.0 12800.0 0.08 1002080.0 24200.78125 0.138609791196016 0.205 0.9698 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F03 compound treatment 512000.0 -578000.0 -2.82 463540.0 -617000.0 -3.67 412070.0 -565809.21875 -3.24066801222453 -5.6212 -0.9944 1049 NINDS_000421 Oc1cc2oc(cc(=O)c2cc1O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F04 compound treatment 981410.0 -109000.0 -0.53 964130.0 -117000.0 -0.7 907930.0 -69949.21875 -0.400633620258103 -0.9387 -0.9762 1050 NINDS_000422 Nc1ccc(cc1)S(=O)(=O)Nc2cnnc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F05 compound treatment 156440.0 -933000.0 -4.56 116360.0 -965000.0 -5.74 134760.0 -843119.21875 -4.82895893554202 -8.7331 -0.9951 1051 NINDS_000423 CC(=O)Oc1ccc(Cl)c2cccnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F06 compound treatment 1068030.0 -21900.0 -0.11 957990.0 -123000.0 -0.73 976480.0 -1399.21875 -0.00801401478619828 -0.4888 -0.661 1052 NINDS_000424 CC[C@H]1CN2CCC1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F07 compound treatment 1234140.0 144000.0 0.7 1322110.0 241000.0 1.43 883680.0 -94199.21875 -0.539525311471724 0.9231 0.5474 1053 NINDS_000425 COc1cc(cc(OC)c1OC)C(=O)NCc2ccc(OCCN(C)C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F08 compound treatment 700960.0 -389000.0 -1.9 632370.0 -449000.0 -2.67 271460.0 -706419.21875 -4.04601072156669 -4.9735 -0.9554 1054 NINDS_000426 CC(C)(C)CC(C)(C)c1ccc(O)c(Cc2ccc(Cl)cc2Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F09 compound treatment 1142500.0 52600.0 0.26 966080.0 -115000.0 -0.68 960370.0 -17509.21875 -0.100283917691412 -0.3042 -0.4127 1055 NINDS_000427 CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F10 compound treatment 349670.0 -740000.0 -3.62 313060.0 -768000.0 -4.57 307760.0 -670119.21875 -3.83810274667784 -6.9406 -0.9949 1056 NINDS_000428 Nc1nc2nc[nH]c2c(=S)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F11 compound treatment 839630.0 -250000.0 -1.22 848640.0 -232000.0 -1.38 900130.0 -77749.21875 -0.445308061143309 -1.7609 -0.9277 1057 NINDS_000429 OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F12 compound treatment 805540.0 -284000.0 -1.39 782330.0 -299000.0 -1.78 770140.0 -207739.21875 -1.18982480097253 -2.5146 -0.9862 1058 NINDS_000430 C[C@@]12CCC3C(CCC4=Cc5oncc5C[C@]34C)C2CC[C@@]1(O)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F13 compound treatment 804040.0 -286000.0 -1.4 964330.0 -117000.0 -0.69 702750.0 -275129.21875 -1.57580051523586 -2.1168 -0.9548 1059 NINDS_000431 CN(C)CC/C=C\1/c2ccccc2COc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F14 compound treatment 501190.0 -589000.0 -2.88 416810.0 -664000.0 -3.95 423300.0 -554579.21875 -3.17634827233468 -5.775 -0.9909 1060 NINDS_000432 CN1CCC(=C2c3ccccc3Sc4ccccc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F15 compound treatment 938690.0 -151000.0 -0.74 717840.0 -363000.0 -2.16 716030.0 -261849.21875 -1.49973941588259 -2.5393 -0.9298 1061 NINDS_000433 Nc1nc(N)c2nc(c(N)nc2n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F16 compound treatment 1041810.0 -48100.0 -0.24 1126780.0 45800.0 0.27 1166680.0 188800.78125 1.08135504372228 0.6457 0.5666 1062 NINDS_000434 COc1ccccc1OCC(O)COC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F17 compound treatment 658720.0 -431000.0 -2.11 637830.0 -443000.0 -2.64 565050.0 -412829.21875 -2.36447622163238 -4.103 -0.9959 1063 NINDS_000435 CC(CNCCc1ccc(O)c(O)c1)Cc2cccc(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F18 compound treatment 1344230.0 254000.0 1.24 1194010.0 113000.0 0.67 1112900.0 135020.78125 0.773330501311209 1.5518 0.9636 1064 NINDS_000436 [O-][N+](=O)O[C@@H]1CO[C@@H]2[C@H](CO[C@H]12)O[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F19 compound treatment 866560.0 -223000.0 -1.09 1079160.0 -1850.0 -0.01 950770.0 -27109.21875 -0.155267844934742 -0.7261 -0.6587 1065 NINDS_000437 CN1C(CC(O)c2ccccc2)CCCC1CC(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F20 compound treatment 49820.0 -1040000.0 -5.08 41660.0 -1040000.0 -6.18 49170.0 -928709.21875 -5.31917501187084 -9.5733 -0.9964 1066 NINDS_000438 OC1OCC=C2OC(=O)C=C12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F21 compound treatment 944770.0 -145000.0 -0.71 1074240.0 -6770.0 -0.04 1037780.0 59900.78125 0.34308127063215 -0.2346 -0.2974 1067 NINDS_000439 CO[C@]1(NC(=O)CSCC#N)C2SCC(=C(N2C1=O)C(=O)O)CSc3nnnn3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F22 compound treatment 1339160.0 249000.0 1.22 957550.0 -123000.0 -0.73 1138980.0 161100.78125 0.92270350365559 0.8119 0.479 1068 NINDS_000440 CN/C(=C\[N+](=O)[O-])/NCCSCc1ccc(CN(C)C)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F23 mock treatment 1014140.0 -75800.0 -0.37 1106730.0 25700.0 0.15 995920.0 18040.78125 0.103328437881545 -0.0658 -0.1591 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 F24 mock treatment 969200.0 -121000.0 -0.59 983810.0 -97200.0 -0.58 995560.0 17680.78125 0.101266540609921 -0.6158 -0.7401 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G01 mock treatment 1206110.0 116000.0 0.57 1082720.0 1710.0 0.01 951810.0 -26069.21875 -0.149311252816715 0.2474 0.4214 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G02 mock treatment 1175280.0 85400.0 0.42 1048490.0 -32500.0 -0.19 981220.0 3340.78125 0.019134299290196 0.1402 0.3046 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G03 compound treatment 609280.0 -481000.0 -2.35 551270.0 -530000.0 -3.15 489630.0 -488249.21875 -2.79644370003779 -4.7891 -0.993 1000045 NINDS_000441 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G04 compound treatment 982240.0 -108000.0 -0.53 921550.0 -159000.0 -0.95 862140.0 -115739.21875 -0.662895498223946 -1.234 -0.9709 1069 NINDS_000442 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G05 compound treatment 852090.0 -238000.0 -1.16 812210.0 -269000.0 -1.6 734770.0 -243109.21875 -1.39240620790967 -2.3977 -0.9918 1070 NINDS_000443 CCC(C(CC)c1ccc(O)cc1)c2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G06 compound treatment 1007400.0 -82500.0 -0.4 967380.0 -114000.0 -0.68 1101490.0 123610.78125 0.707979812785543 -0.2142 -0.2023 1000116 NINDS_000444 CC(=O)CC(c1ccccc1)c2c(O)c3ccccc3oc2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G07 compound treatment 762720.0 -327000.0 -1.6 828550.0 -252000.0 -1.5 696840.0 -281039.21875 -1.60964999544504 -2.7191 -0.9995 1000117 NINDS_000445 CC(=O)[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G08 compound treatment 1034600.0 -55300.0 -0.27 1055650.0 -25400.0 -0.15 929870.0 -48009.21875 -0.274972436537409 -0.4019 -0.9707 1073 NINDS_000446 CC(N)C(=O)NC(Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G09 compound treatment 1076350.0 -13600.0 -0.07 953360.0 -128000.0 -0.76 924350.0 -53529.21875 -0.306588194702324 -0.6536 -0.7957 3173981 NINDS_000447 CCOC(=O)OC(C)OC(=O)C1N2C(SC1(C)C)C(NC(=O)[C@H](N)c3ccccc3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G10 compound treatment 1158240.0 68300.0 0.33 1082940.0 1930.0 0.01 1091950.0 114070.78125 0.653339535087483 0.5765 0.7857 1075 NINDS_000448 CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G11 compound treatment 1176800.0 86900.0 0.42 948760.0 -132000.0 -0.79 903760.0 -74119.21875 -0.424517263654425 -0.4541 -0.459 1076 NINDS_000449 Cc1cccc(C)c1NC2=NCCCS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G12 compound treatment 1117790.0 27900.0 0.14 1006880.0 -74100.0 -0.44 996450.0 18570.78125 0.106364008864771 -0.1145 -0.2418 1077 NINDS_000450 CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4c(ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G13 compound treatment 1242020.0 152000.0 0.74 1394310.0 313000.0 1.86 1061180.0 83300.78125 0.477104593287767 1.7801 0.8634 1000118 NINDS_000451 CN[C@@H](C)[C@@H](O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G14 compound treatment 856000.0 -234000.0 -1.14 883130.0 -198000.0 -1.18 912510.0 -65369.21875 -0.374401704969098 -1.5554 -0.9244 1079 NINDS_000452 N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G15 compound treatment 1011540.0 -78400.0 -0.38 1089280.0 8270.0 0.05 997120.0 19240.78125 0.110201428786962 -0.1291 -0.3215 1080 NINDS_000453 N[C@H](Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G16 compound treatment 1023680.0 -66200.0 -0.32 1021280.0 -59700.0 -0.36 1018800.0 40920.78125 0.234373464478149 -0.2566 -0.48 1081 NINDS_000454 Cc1c(N)c(=O)n(c2ccccc2)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G17 compound treatment 658820.0 -431000.0 -2.11 665080.0 -416000.0 -2.47 704050.0 -273829.21875 -1.56835477508833 -3.5496 -0.9839 1082 NINDS_000455 CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G18 compound treatment 1049970.0 -40000.0 -0.2 1125940.0 44900.0 0.27 1171760.0 193880.78125 1.11045070522188 0.6827 0.5892 1083 NINDS_000456 C(C1=NCCN1)c2cccc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G19 compound treatment 1270740.0 181000.0 0.88 1152920.0 71900.0 0.43 1015250.0 37370.78125 0.214040866382959 0.8805 0.8765 1000119 NINDS_000457 N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G20 compound treatment 255300.0 -835000.0 -4.08 300740.0 -780000.0 -4.64 251420.0 -726459.21875 -4.16078966968714 -7.4354 -0.9983 3173985 NINDS_000458 CO[C@H]1CC(O[C@H]/2[C@@H](C)\C=C\C=C\3/CO[C@@H]4CC(=C[C@@H](C(=O)O[C@H]5C[C@@H](C\C=C2/C)O[C@@]6(CC[C@H](C)[C@H](O6)C7CCCCC7)C5)[C@@]43O)C)O[C@@H](C)C1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G21 compound treatment 990650.0 -99300.0 -0.49 959080.0 -122000.0 -0.73 996680.0 18800.78125 0.107681332121642 -0.6365 -0.7241 1086 NINDS_000459 CC(C)C(=O)Nc1ccc([N+](=O)[O-])c(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G22 compound treatment 636480.0 -453000.0 -2.22 539310.0 -542000.0 -3.22 522980.0 -454899.21875 -2.60543182779143 -4.6431 -0.9883 1087 NINDS_000460 Oc1ccc(Cl)cc1Cc2cc(Cl)ccc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G23 mock treatment 1014940.0 -75000.0 -0.37 1101320.0 20300.0 0.12 1011470.0 33590.78125 0.192390945030898 -0.0307 -0.0713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 G24 mock treatment 1164230.0 74300.0 0.36 1127360.0 46300.0 0.28 1079970.0 102090.78125 0.584724175881744 0.7063 0.9527 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H01 mock treatment 1187390.0 97500.0 0.48 1193490.0 112000.0 0.67 1035630.0 57750.78125 0.330767161926612 0.8521 0.9626 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H02 mock treatment 1177890.0 88000.0 0.43 1175070.0 94100.0 0.56 1102650.0 124770.78125 0.714623703994112 0.9837 0.9796 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H03 compound treatment 984580.0 -105000.0 -0.51 991400.0 -89600.0 -0.53 903080.0 -74799.21875 -0.428411958500827 -0.8522 -0.9957 836 NINDS_000461 CNC(C)C(O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H04 compound treatment 64820.0 -1030000.0 -5.01 45640.0 -1040000.0 -6.16 55260.0 -922619.21875 -5.28429458302585 -9.4972 -0.996 1088 NINDS_000462 CCN(CC)CCOc1ccc(cc1)/C(=C(\Cl)/c2ccccc2)/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H05 compound treatment 995460.0 -94500.0 -0.46 1075250.0 -5760.0 -0.03 983680.0 5800.78125 0.0332239306462994 -0.2671 -0.5756 3044782 NINDS_000463 NC(=N)N.OC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H06 compound treatment 1046960.0 -43000.0 -0.21 1127790.0 46800.0 0.28 992290.0 14410.78125 0.0825376403926612 0.0871 0.2431 1090 NINDS_000464 CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H07 compound treatment 994430.0 -95500.0 -0.47 1018750.0 -62300.0 -0.37 841060.0 -136819.21875 -0.783631038462425 -0.9356 -0.9505 1091 NINDS_000465 CCc1cn(C2OCC(O)C2CO)c(=O)nc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H08 compound treatment 1146600.0 56700.0 0.28 1198190.0 117000.0 0.7 1076670.0 98790.78125 0.565823450891849 0.8889 0.9462 1092 NINDS_000466 CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H09 compound treatment 1281690.0 192000.0 0.94 1182880.0 102000.0 0.61 1126400.0 148520.78125 0.850651648997142 1.3818 0.9849 1093 NINDS_000467 NCCC(O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2N)[C@H](OC3O[C@H](CO)[C@H](O)[C@H]3O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H10 compound treatment 984240.0 -106000.0 -0.52 1171890.0 90900.0 0.54 972120.0 -5759.21875 -0.0329858817425441 -0.0052 -0.0069 1094 NINDS_000468 COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H11 compound treatment 759290.0 -331000.0 -1.62 860010.0 -221000.0 -1.31 698890.0 -278989.21875 -1.59790863598162 -2.614 -0.9958 1095 NINDS_000469 NC(CO)C(=O)NNCc1ccc(O)c(O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H12 compound treatment 1270720.0 181000.0 0.88 1167480.0 86500.0 0.51 979360.0 1480.78125 0.00848116338680079 0.8118 0.7942 1096 NINDS_000470 C[N+](C)(C)CC(O)CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H13 compound treatment 1067940.0 -22000.0 -0.11 985640.0 -95400.0 -0.57 1256160.0 278280.78125 1.59385106556949 0.5308 0.3131 1097 NINDS_000471 OC(=O)c1cc(=O)c2ccccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H14 compound treatment 1238950.0 149000.0 0.73 1169540.0 88500.0 0.53 1120960.0 143080.78125 0.819494090225922 1.1975 0.9847 1098 NINDS_000472 C[C@@]12C[C@H](O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H15 compound treatment 1033410.0 -56500.0 -0.28 1256260.0 175000.0 1.04 965600.0 -12279.21875 -0.0703291323286392 0.4017 0.3718 1099 NINDS_000473 CC(=O)NCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H16 compound treatment 1075730.0 -14200.0 -0.07 1061250.0 -19800.0 -0.12 989930.0 12050.78125 0.0690207582786758 -0.068 -0.4449 1100 NINDS_000474 CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H17 compound treatment 1003540.0 -86400.0 -0.42 1038660.0 -42400.0 -0.25 900850.0 -77029.21875 -0.441184266600059 -0.6438 -0.9748 1101 NINDS_000475 CCCC1O[C@@H]2CC3C4CCC5=CC(=O)C=CC5(C)C4[C@@H](O)CC3(C)[C@@]2(O1)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H18 compound treatment 1030190.0 -59700.0 -0.29 969570.0 -111000.0 -0.66 1160960.0 183080.78125 1.04859378707313 0.0543 0.0426 1102 NINDS_000476 CC(C(=O)O)c1ccc(cc1)C(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H19 compound treatment 1196320.0 106000.0 0.52 1222360.0 141000.0 0.84 996220.0 18340.78125 0.1050466856079 0.8461 0.8513 3471036 NINDS_000477 OC(=O)C1=C(C[n+]2ccccc2)CSC3C(NC(=O)Cc4cccs4)C(=O)N31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H20 compound treatment 1040960.0 -49000.0 -0.24 1137370.0 56400.0 0.34 1064860.0 86980.78125 0.498181765397711 0.343 0.5307 1104 NINDS_000478 C[C@H](CCC(=O)O)[C@H]1CCC2C3C(CC(=O)[C@]12C)[C@@]4(C)CCC(=O)CC4CC3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H21 compound treatment 629940.0 -460000.0 -2.25 662560.0 -418000.0 -2.49 587650.0 -390229.21875 -2.23503489291371 -4.0246 -0.9987 3044756 NINDS_000479 CC(CN(C)C)CN1c2ccccc2Sc3ccccc13.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H22 compound treatment 63970.0 -1030000.0 -5.01 40970.0 -1040000.0 -6.18 52990.0 -924889.21875 -5.29729599082193 -9.5232 -0.9959 1105 NINDS_000480 CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H23 mock treatment 1111090.0 21200.0 0.1 1103100.0 22100.0 0.13 977280.0 -599.21875 -0.00343202084925409 0.1336 0.7988 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 H24 mock treatment 1081640.0 -8280.0 -0.04 1118690.0 37700.0 0.22 1043120.0 65240.78125 0.373666080161252 0.3217 0.7353 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I01 mock treatment 1082940.0 -6980.0 -0.03 1015630.0 -65400.0 -0.39 929950.0 -47929.21875 -0.274514237143714 -0.4027 -0.8439 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I02 mock treatment 1089230.0 -694.0 0.0 1067260.0 -13800.0 -0.08 929850.0 -48029.21875 -0.275086986385833 -0.208 -0.7247 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I03 compound treatment 1059260.0 -30700.0 -0.15 1001190.0 -79800.0 -0.47 996530.0 18650.78125 0.106822208258465 -0.2989 -0.5871 74 NINDS_000481 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I04 compound treatment 1091620.0 1700.0 0.01 980230.0 -101000.0 -0.6 933180.0 -44699.21875 -0.256014436623302 -0.489 -0.7503 1106 NINDS_000482 CCC(=O)c1c(O)cc(O)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I05 compound treatment 1123360.0 33400.0 0.16 1081120.0 108.0 0.0 920130.0 -57749.21875 -0.330758212719704 -0.0963 -0.261 1107 NINDS_000483 OC(=O)CN1CCNC1=N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I06 compound treatment 1016850.0 -73100.0 -0.36 1046190.0 -34800.0 -0.21 944870.0 -33009.21875 -0.189060050219705 -0.4348 -0.9578 1108 NINDS_000484 Cc1cc(=O)n(c2ccccc2)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I07 compound treatment 562310.0 -528000.0 -2.58 471900.0 -609000.0 -3.62 501570.0 -476309.21875 -2.7280574405289 -5.1546 -0.9882 353 NINDS_000485 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I08 compound treatment 1041160.0 -48800.0 -0.24 1054790.0 -26200.0 -0.16 855100.0 -122779.21875 -0.703217044869055 -0.6336 -0.8351 1000121 NINDS_000486 C/C(=C\CO)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I09 compound treatment 1215090.0 125000.0 0.61 1056740.0 -24300.0 -0.14 897030.0 -80849.21875 -0.463063287648968 0.0024 0.0031 1110 NINDS_000487 C[C@H]1CC2C3CC[C@](OC(=O)C)(C(=O)C)[C@@]3(C)CCC2[C@@]4(C)CCC(=O)C=C14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I10 compound treatment 1048000.0 -41900.0 -0.2 941040.0 -140000.0 -0.83 906840.0 -71039.21875 -0.40687658699719 -0.8337 -0.8787 1111 NINDS_000488 CCC(C)C1NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(CCNC(=O)C(NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(NC1=O)C(C)CC)C(C)O)NC(=O)C(CCNCS(=O)(=O)O)NC(=O)C(NC(=O)C(CCNCS(=O)(=O)O)NC(=O)CCCCC(C)C)C(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I11 compound treatment 995420.0 -94500.0 -0.46 1069190.0 -11800.0 -0.07 1112760.0 134880.78125 0.772528652372244 0.1389 0.1538 1112 NINDS_000489 CC(C)N(CCC(C(=O)N)(c1ccccc1)c2ccccn2)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I12 compound treatment 987600.0 -102000.0 -0.5 1120550.0 39500.0 0.24 908480.0 -69399.21875 -0.397483499426454 -0.3824 -0.5618 1113 NINDS_000490 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(=O)O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I13 compound treatment 1079040.0 -10900.0 -0.05 1173610.0 92600.0 0.55 1044590.0 66710.78125 0.382085494020387 0.5078 0.7553 1114 NINDS_000491 NS(=O)(=O)c1cc2c(N=C(CSCc3ccccc3)NS2(=O)=O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I14 compound treatment 956660.0 -133000.0 -0.65 741020.0 -340000.0 -2.02 718560.0 -259319.21875 -1.485248860057 -2.4007 -0.9263 1115 NINDS_000492 C[C@@]12CCC3C(CCC4=C3CCC(=O)C4)C2CC[C@@]1(O)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I15 compound treatment 557440.0 -532000.0 -2.6 502670.0 -578000.0 -3.44 462730.0 -515149.21875 -2.95051324616754 -5.1911 -0.9935 1116 NINDS_000493 S=c1[nH]cnc2nc[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I16 compound treatment 1239680.0 150000.0 0.73 1056330.0 -24700.0 -0.15 1109200.0 131320.78125 0.752138779352842 0.7719 0.7286 1117 NINDS_000494 Nc1nc(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)cnc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I17 compound treatment 58800.0 -1030000.0 -5.04 38280.0 -1040000.0 -6.2 47640.0 -930239.21875 -5.32793807527525 -9.5647 -0.996 2549 NINDS_000495 C[n+]1cc2c3OCOc3ccc2c4ccc5cc6OCOc6cc5c14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I18 compound treatment 22900.0 -1070000.0 -5.21 13960.0 -1070000.0 -6.35 19680.0 -958199.21875 -5.48807876337145 -9.8419 -0.9964 3174099 NINDS_000496 Nc1cccc(c1)C(=C2C=CC(=N)C=C2)c3cccc(N)c3.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I19 compound treatment 1093030.0 3110.0 0.02 1071680.0 -9330.0 -0.06 891890.0 -85989.21875 -0.492502598693834 -0.3076 -0.6204 2069294 NINDS_000497 C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=CC4(C)C3(F)[C@@H](O)CC2(C)C1C(=O)COC(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I20 compound treatment 1167330.0 77400.0 0.38 1017310.0 -63700.0 -0.38 1148670.0 170790.78125 0.978202905216826 0.5644 0.5062 1119 NINDS_000498 CSCCC(NC=O)C(=O)NC(Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I21 compound treatment 774430.0 -315000.0 -1.54 723950.0 -357000.0 -2.12 791110.0 -186769.21875 -1.06971928490038 -2.7334 -0.9647 3174101 NINDS_000499 CN1CCc2c(C1)c3ccccc3n2Cc4ccccc4.OS(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I22 compound treatment 1162590.0 72700.0 0.36 1310330.0 229000.0 1.36 1006420.0 28540.78125 0.163467108303938 1.0867 0.766 1120 NINDS_000500 Oc1ccc(cc1[N+](=O)[O-])[As](=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I23 mock treatment 1282290.0 192000.0 0.94 1154160.0 73100.0 0.43 997360.0 19480.78125 0.111576026968045 0.8582 0.8239 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 I24 mock treatment 1120040.0 30100.0 0.15 1135770.0 54800.0 0.33 937310.0 -40569.21875 -0.232359892923828 0.1388 0.3256 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J01 mock treatment 1306930.0 217000.0 1.06 1167100.0 86100.0 0.51 1030350.0 52470.78125 0.300526001942781 1.0812 0.8898 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J02 mock treatment 1124570.0 34600.0 0.17 1055360.0 -25700.0 -0.15 1014400.0 36520.78125 0.209172497824956 0.1304 0.4217 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J03 compound treatment 1512390.0 422000.0 2.06 1223280.0 142000.0 0.85 985280.0 7400.78125 0.0423879185201878 1.7046 0.764 1000122 NINDS_000501 O[C@@H]([C@@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J04 compound treatment 1140900.0 51000.0 0.25 1043780.0 -37200.0 -0.22 951920.0 -25959.21875 -0.148681228650385 -0.0699 -0.1915 1122 NINDS_000502 N(=Nc1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J05 compound treatment 986510.0 -103000.0 -0.51 928290.0 -153000.0 -0.91 772480.0 -205399.21875 -1.17642246870697 -1.4953 -0.9526 3174102 NINDS_000503 OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J06 compound treatment 1106910.0 17000.0 0.08 1183060.0 102000.0 0.61 1003760.0 25880.78125 0.148231978463598 0.4839 0.7678 1123 NINDS_000504 Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J07 compound treatment 999770.0 -90200.0 -0.44 1005170.0 -75800.0 -0.45 989120.0 11240.78125 0.0643814894175199 -0.4775 -0.7536 1124 NINDS_000505 CN1C2CC[C@@H]1C[C@H](C2)OC(=O)[C@H](CO)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J08 compound treatment 1058410.0 -31500.0 -0.15 1042900.0 -38100.0 -0.23 1046240.0 68360.78125 0.391535856515335 0.0063 0.0132 1125 NINDS_000506 CCOC(=O)NNc1nncc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J09 compound treatment 1105970.0 16000.0 0.08 1070760.0 -10300.0 -0.06 957660.0 -20219.21875 -0.11580542215281 -0.0568 -0.3723 1126 NINDS_000507 O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J10 compound treatment 1389280.0 299000.0 1.46 1092400.0 11400.0 0.07 1091530.0 113650.78125 0.650933988270587 1.2593 0.7859 1127 NINDS_000508 CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J11 compound treatment 156010.0 -934000.0 -4.56 76510.0 -1000000.0 -5.97 103680.0 -874199.21875 -5.0069693999923 -8.9739 -0.9936 3174103 NINDS_000509 C/C/1=C\CC[C@@]2(C)OC2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J12 compound treatment 1211370.0 121000.0 0.59 1224400.0 143000.0 0.85 1156370.0 178490.78125 1.02230459685991 1.4251 0.9778 1129 NINDS_000510 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J13 compound treatment 86410.0 -1000000.0 -4.9 56080.0 -1020000.0 -6.09 67360.0 -910519.21875 -5.21499192472957 -9.3605 -0.9957 1130 NINDS_000511 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J14 compound treatment 1420040.0 330000.0 1.61 1082820.0 1810.0 0.01 1142190.0 164310.78125 0.941088754327578 1.4807 0.7929 1131 NINDS_000512 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J15 compound treatment 1213450.0 124000.0 0.6 1077600.0 -3410.0 -0.02 1063200.0 85320.78125 0.488674127978551 0.6189 0.7967 1132 NINDS_000513 CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J16 compound treatment 632070.0 -458000.0 -2.24 631680.0 -449000.0 -2.67 533090.0 -444789.21875 -2.5475268794133 -4.305 -0.9973 1133 NINDS_000514 CCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J17 compound treatment 1168960.0 79000.0 0.39 1143060.0 62000.0 0.37 969950.0 -7929.21875 -0.0454145402965052 0.4098 0.7644 1134 NINDS_000515 CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J18 compound treatment 104420.0 -986000.0 -4.81 65280.0 -1020000.0 -6.04 73230.0 -904649.21875 -5.18137154421724 -9.2587 -0.9954 1135 NINDS_000516 OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J19 compound treatment 1212290.0 122000.0 0.6 1242410.0 161000.0 0.96 1076930.0 99050.78125 0.567312598921356 1.2268 0.9698 1136 NINDS_000517 C[C@@]12C[C@H](O)C3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C(=O)COC(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J20 compound treatment 1182240.0 92300.0 0.45 1089810.0 8800.0 0.05 891170.0 -86709.21875 -0.496626393237084 0.0039 0.0058 1137 NINDS_000518 CC(=O)Oc1ccc2C3CCC4(C)C(CCC4=O)C3CCc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J21 compound treatment 935920.0 -154000.0 -0.75 926400.0 -155000.0 -0.92 925970.0 -51909.21875 -0.297309656980012 -1.1369 -0.9283 1138 NINDS_000519 CC/C(=C(/CC)\c1ccc(O)cc1)/c2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J22 compound treatment 817690.0 -272000.0 -1.33 883390.0 -198000.0 -1.18 776280.0 -201599.21875 -1.15465799750648 -2.1131 -0.9979 1139 NINDS_000520 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2CC[C@@]1(O)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J23 mock treatment 1121760.0 31800.0 0.16 1188800.0 108000.0 0.64 1100670.0 122790.78125 0.703283269000175 0.8659 0.8981 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 J24 mock treatment 1153620.0 63700.0 0.31 1164860.0 83800.0 0.5 1024710.0 46830.78125 0.268222944687324 0.6224 0.9634 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K01 mock treatment 1283430.0 194000.0 0.95 1088820.0 7810.0 0.05 960120.0 -17759.21875 -0.101715790796707 0.5139 0.5398 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K02 mock treatment 1244170.0 154000.0 0.75 1254530.0 174000.0 1.03 1032330.0 54450.78125 0.311866436936718 1.2109 0.9207 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K03 compound treatment 206330.0 -884000.0 -4.32 182470.0 -899000.0 -5.34 152490.0 -825389.21875 -4.7274104949145 -8.3068 -0.9962 3174105 NINDS_000521 CN(C)c1ccc2[n+](C)c(/C=C/c3cc(C)n(c3C)c4ccccc4)ccc2c1.OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(=O)O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K04 compound treatment 971000.0 -119000.0 -0.58 1096290.0 15300.0 0.09 940240.0 -37639.21875 -0.21557834012977 -0.4075 -0.6505 1140 NINDS_000522 CC(=O)OC/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K05 compound treatment 837530.0 -252000.0 -1.23 772190.0 -309000.0 -1.84 601480.0 -376399.21875 -2.15582367272879 -3.0169 -0.9767 1141 NINDS_000523 CN1C2CCC1CC(C2)OC(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K06 compound treatment 1021120.0 -68800.0 -0.34 1015360.0 -65700.0 -0.39 838530.0 -139349.21875 -0.798121594288011 -0.8803 -0.9267 1142 NINDS_000524 Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K07 compound treatment 1122560.0 32600.0 0.16 1106820.0 25800.0 0.15 895290.0 -82589.21875 -0.473029124461821 -0.0924 -0.177 3174106 NINDS_000525 CN(C)CCCO[C@H]1[C@H](OC2OC(C)(C)O[C@H]12)C(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K08 compound treatment 1181920.0 92000.0 0.45 1173440.0 92400.0 0.55 1023010.0 45130.78125 0.258486207571318 0.7261 0.9609 1144 NINDS_000526 O=C1NCC2(CCN(CCc3ccccc3)CC2)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K09 compound treatment 1352880.0 263000.0 1.28 1200890.0 120000.0 0.71 1006560.0 28680.78125 0.164268957242903 1.2482 0.8443 3174107 NINDS_000527 CN[C@@H]1C(O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3OC(=CC[C@H]3N)CN)[C@@H]2O)OC[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K10 compound treatment 1291750.0 202000.0 0.99 1214810.0 134000.0 0.8 964210.0 -13669.21875 -0.0782903467940797 0.9835 0.7747 1146 NINDS_000528 Nc1ccc(cc1)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K11 compound treatment 1096390.0 6470.0 0.03 1034190.0 -46800.0 -0.28 839720.0 -138159.21875 -0.791305878306807 -0.5994 -0.714 1147 NINDS_000529 COc1c2ccoc2cc3oc(=O)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K12 compound treatment 1288530.0 199000.0 0.97 1058080.0 -22900.0 -0.14 995400.0 17520.78125 0.100350141822532 0.5394 0.5476 3174108 NINDS_000530 CC(=O)N[C@H](CS)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K13 compound treatment 1230620.0 141000.0 0.69 1170080.0 89100.0 0.53 953720.0 -24159.21875 -0.13837174229226 0.6228 0.7087 1149 NINDS_000531 CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K14 compound treatment 1241040.0 151000.0 0.74 1119700.0 38700.0 0.23 979800.0 1920.78125 0.0110012600521201 0.5655 0.7311 1150 NINDS_000532 OC(=O)CCCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K15 compound treatment 1330480.0 241000.0 1.18 1154930.0 73900.0 0.44 1006030.0 28150.78125 0.161233386259678 1.0254 0.8105 1151 NINDS_000533 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K16 compound treatment 1063280.0 -26600.0 -0.13 1102630.0 21600.0 0.13 965210.0 -12669.21875 -0.0725628543728995 -0.0428 -0.2176 1152 NINDS_000534 CN(C)CCN(Cc1ccccc1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K17 compound treatment 246120.0 -844000.0 -4.12 190990.0 -890000.0 -5.29 198510.0 -779369.21875 -4.46383129369178 -8.0131 -0.9944 3174220 NINDS_000535 CO[C@@H]1C[C@@H](C[C@H]2CC[C@H](C)[C@@H](O2)[C@@H](C)C(=O)O)O[C@]3(O[C@@](C)(C[C@H]3C)[C@H]4CC[C@](C)(O4)C5O[C@H](C[C@@H]5C)C6O[C@@](O)(CO)[C@H](C)C[C@@H]6C)[C@@H]1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K18 compound treatment 1387140.0 297000.0 1.45 1073850.0 -7160.0 -0.04 986310.0 8430.78125 0.0482872357140034 0.8417 0.579 1154 NINDS_000536 O=C1CC2OCC=C3CN4CC[C@]56C4C[C@@H]3[C@@H]2C6N1c7ccccc75 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K19 compound treatment 1300590.0 211000.0 1.03 1280320.0 199000.0 1.19 998640.0 20760.78125 0.118907217267156 1.3472 0.8558 1155 NINDS_000537 Nc1ccc(cc1)S(=O)(=O)NC(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K20 compound treatment 903480.0 -186000.0 -0.91 1090580.0 9570.0 0.06 895540.0 -82339.21875 -0.471597251356526 -0.7654 -0.745 1156 NINDS_000538 OC(=O)c1cc(O)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K21 compound treatment 1149440.0 59500.0 0.29 1150820.0 69800.0 0.42 1109920.0 132040.78125 0.756262573896092 0.8442 0.9273 3055 NINDS_000539 NC(=N)NCCN1CCCCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K22 compound treatment 1039240.0 -50700.0 -0.25 914560.0 -166000.0 -0.99 868640.0 -109239.21875 -0.625666797486275 -1.0757 -0.8987 86 NINDS_000540 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K23 mock treatment 1022570.0 -67400.0 -0.33 1070210.0 -10800.0 -0.06 942720.0 -35159.21875 -0.201374158925243 -0.3433 -0.8779 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 K24 mock treatment 1214250.0 124000.0 0.61 1266720.0 186000.0 1.1 1086720.0 108840.78125 0.623384749724711 1.3482 0.9588 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L01 mock treatment 1154720.0 64800.0 0.32 1046970.0 -34000.0 -0.2 1086590.0 108710.78125 0.622640175709957 0.4254 0.5849 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L02 mock treatment 1140200.0 50300.0 0.25 1163360.0 82300.0 0.49 961470.0 -16409.21875 -0.0939836760281136 0.3703 0.6662 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L03 compound treatment 660540.0 -429000.0 -2.1 622530.0 -458000.0 -2.73 541310.0 -436569.21875 -2.5004468917112 -4.2289 -0.9944 1157 NINDS_000541 CC(=O)N1CCN(CC1)c2ccc(OCC3CO[C@@](Cn4ccnc4)(O3)c5ccc(Cl)cc5Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L04 compound treatment 67360.0 -1020000.0 -5.0 40290.0 -1040000.0 -6.19 46200.0 -931679.21875 -5.33618566436174 -9.5384 -0.9959 1158 NINDS_000542 C(C(C1CCCCC1)C2CCCCC2)C3CCCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L05 compound treatment 1205820.0 116000.0 0.57 1124390.0 43400.0 0.26 916180.0 -61699.21875 -0.353381807783366 0.2718 0.3799 1159 NINDS_000543 Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L06 compound treatment 1078640.0 -11300.0 -0.06 1077870.0 -3140.0 -0.02 956660.0 -21219.21875 -0.12153291457399 -0.1128 -0.837 1160 NINDS_000544 OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L07 compound treatment 1067870.0 -22100.0 -0.11 1344130.0 263000.0 1.56 926340.0 -51539.21875 -0.295190484784175 0.6707 0.4203 3045799 NINDS_000545 NC(=Nc1nc(CSCC/C(=N\S(=O)(=O)N)/N)cs1)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L08 compound treatment 1017050.0 -72900.0 -0.36 1065600.0 -15400.0 -0.09 890560.0 -87319.21875 -0.500120163614004 -0.5472 -0.8816 1162 NINDS_000546 Cc1c(NC(=O)c2cccnc2)c(=O)n(c3ccccc3)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L09 compound treatment 1375520.0 286000.0 1.4 1102720.0 21700.0 0.13 954980.0 -22899.21875 -0.131155101841573 0.8044 0.5715 1163 NINDS_000547 Oc1ccc2C[C@H]3N(CC4CC4)CCC5([C@H]6Oc1c25)[C@@]3(O)CCC6=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L10 compound treatment 1033390.0 -56500.0 -0.28 983090.0 -97900.0 -0.58 894400.0 -83479.21875 -0.478126592716672 -0.7717 -0.9617 1164 NINDS_000548 CCN(CC)C(=O)N1CCN(C)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L11 compound treatment 1243720.0 154000.0 0.75 1208480.0 127000.0 0.76 989670.0 11790.78125 0.067531610249169 0.9105 0.8513 1000123 NINDS_000549 CC(=O)OCC(=O)[C@@]1(O)[C@@H](CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L12 compound treatment 876210.0 -214000.0 -1.04 876160.0 -205000.0 -1.22 741290.0 -236589.21875 -1.35506295732358 -2.0885 -0.9945 3174224 NINDS_000550 CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c4c(O)c(\C=N/N5CCN(C)CC5)c(NC(=O)/C(=C\C=C\C(C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](OC(=O)C)[C@@H]1C)/C)c(O)c4c(O)c3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L13 compound treatment 1296390.0 206000.0 1.01 1336680.0 256000.0 1.52 998690.0 20810.78125 0.119193591888215 1.529 0.8362 1167 NINDS_000551 NCCCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L14 compound treatment 483080.0 -607000.0 -2.96 394470.0 -687000.0 -4.08 411590.0 -566289.21875 -3.2434172085867 -5.9415 -0.9905 1168 NINDS_000552 CC12CCC3C(CCc4cc(OCc5ccccc5)ccc34)C2C[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L15 compound treatment 975130.0 -115000.0 -0.56 913730.0 -167000.0 -0.99 778620.0 -199259.21875 -1.14125566524092 -1.557 -0.9644 1169 NINDS_000553 C[C@@]12CCC3C(CCC4=CC(=O)CC[C@H]34)C2CC[C@@]1(O)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L16 compound treatment 1076660.0 -13300.0 -0.06 1131140.0 50100.0 0.3 881560.0 -96319.21875 -0.551667595404626 -0.1838 -0.2916 1170 NINDS_000554 CC(=O)OCC(=O)[C@]12OC(C)(C)O[C@@H]2C[C@H]3C4C[C@H](F)C5=CC(=O)C=CC5(C)[C@@]4(F)[C@@H](O)C[C@@]31C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L17 compound treatment 1084500.0 -5420.0 -0.03 1281240.0 200000.0 1.19 971300.0 -6579.21875 -0.0376824255279119 0.6504 0.5458 1171 NINDS_000555 CC(=O)Oc1ccccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L18 compound treatment 929030.0 -161000.0 -0.79 1136000.0 55000.0 0.33 897930.0 -79949.21875 -0.457908544469906 -0.5294 -0.5477 430 NINDS_000556 NC(=O)NO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L19 compound treatment 1416770.0 327000.0 1.6 1160890.0 79900.0 0.48 920830.0 -57049.21875 -0.326748968024878 1.0076 0.5935 1172 NINDS_000557 CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L20 compound treatment 1193830.0 104000.0 0.51 1203230.0 122000.0 0.73 940000.0 -37879.21875 -0.216952938310853 0.5874 0.6436 1000124 NINDS_000558 CN1C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L21 compound treatment 927940.0 -162000.0 -0.79 923200.0 -158000.0 -0.94 709300.0 -268579.21875 -1.53828543987713 -1.8869 -0.9587 1174 NINDS_000559 CN(C)CCCN1c2ccccc2CCc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L22 compound treatment 997670.0 -92300.0 -0.45 1128560.0 47500.0 0.28 1130300.0 152420.78125 0.872988869439745 0.407 0.3981 1175 NINDS_000560 Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L23 mock treatment 1091300.0 1380.0 0.01 1225050.0 144000.0 0.86 969190.0 -8689.21875 -0.0497674345366022 0.4697 0.5474 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 L24 mock treatment 999600.0 -90300.0 -0.44 1065720.0 -15300.0 -0.09 940690.0 -37189.21875 -0.213000968540239 -0.4303 -0.8633 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M01 mock treatment 1178790.0 88900.0 0.43 1167550.0 86500.0 0.51 1062570.0 84690.78125 0.485065807753208 0.8278 0.9976 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M02 mock treatment 1191050.0 101000.0 0.49 998240.0 -82800.0 -0.49 920550.0 -57329.21875 -0.328352665902809 -0.1885 -0.2445 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M03 compound treatment 1263240.0 173000.0 0.85 1082900.0 1890.0 0.01 912360.0 -65519.21875 -0.375260828832275 0.2787 0.3009 1176 NINDS_000561 CC[C@@H](CO)NCCN[C@@H](CC)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M04 compound treatment 1089940.0 16.3 0.0 1089230.0 8220.0 0.05 896960.0 -80919.21875 -0.46346421211845 -0.2393 -0.5135 3174226 NINDS_000562 CC[N+](C)(C)Cc1ccc(Br)cc1.Cc1ccc(cc1)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M05 compound treatment 1369830.0 280000.0 1.37 1356320.0 275000.0 1.64 946410.0 -31469.21875 -0.180239711891088 1.6307 0.7617 1177 NINDS_000563 Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M06 compound treatment 1218930.0 129000.0 0.63 1117280.0 36300.0 0.22 1012190.0 34310.78125 0.196514739574148 0.6019 0.8666 3174227 NINDS_000564 CC[C@@H]1[C@@H](O)N2[C@H]3C[C@@]45C(O)C3[C@@H]1CC2[C@@H]5N(C)c6ccccc64 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M07 compound treatment 814950.0 -275000.0 -1.34 836320.0 -245000.0 -1.46 770080.0 -207799.21875 -1.1901684505178 -2.3029 -0.9967 1179 NINDS_000565 CC12CC[C@H]3C(CCc4cc(O)ccc34)[C@@H]2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M08 compound treatment 984090.0 -106000.0 -0.52 1028320.0 -52700.0 -0.31 778560.0 -199319.21875 -1.14159931478619 -1.1385 -0.8813 1180 NINDS_000566 Fc1ccc(cc1)C(=O)CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M09 compound treatment 1232280.0 142000.0 0.7 1241600.0 161000.0 0.95 899280.0 -78599.21875 -0.450176429701312 0.693 0.5481 1181 NINDS_000567 Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M10 compound treatment 1364070.0 274000.0 1.34 1364040.0 283000.0 1.68 973120.0 -4759.21875 -0.0272583893213639 1.7293 0.8039 3471107 NINDS_000568 NC(=O)c1cc[n+](CC2=C(N3C(SC2)C(NC(=O)C(c4ccccc4)S(=O)(=O)O)C3=O)C(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M11 compound treatment 1333380.0 243000.0 1.19 1347320.0 266000.0 1.58 1180850.0 202970.78125 1.16251361133041 2.2722 0.9894 3174228 NINDS_000569 CN[C@H]1C(O)C(O)C(CO)OC1OC2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](NC(=N)N)[C@@H](O)[C@@H]3NC(=N)N)OC(C)[C@]2(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M12 compound treatment 1553530.0 464000.0 2.27 1358730.0 278000.0 1.65 1065230.0 87350.78125 0.500300937593547 2.5501 0.8955 1184 NINDS_000570 Nc1ncnc2n(cnc12)C3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M13 compound treatment 1285180.0 195000.0 0.95 1405560.0 325000.0 1.93 1169770.0 191890.78125 1.09905299530373 2.2996 0.9514 1000126 NINDS_000571 C[C@H](CCC(=O)O)[C@H]1CCC2C3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M14 compound treatment 1135600.0 45700.0 0.22 979840.0 -101000.0 -0.6 941720.0 -36159.21875 -0.207101651346423 -0.3381 -0.5014 338 NINDS_000572 Nc1ccncc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M15 compound treatment 957610.0 -132000.0 -0.65 983520.0 -97500.0 -0.58 883910.0 -93969.21875 -0.538207988214852 -1.0187 -0.9971 1186 NINDS_000573 Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M16 compound treatment 1331040.0 241000.0 1.18 1249330.0 168000.0 1.0 982530.0 4650.78125 0.0266373143619421 1.2734 0.8236 1187 NINDS_000574 C[C@@]12CCC3C(CCc4cc(OS(=O)(=O)O)ccc34)C2CC[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M17 compound treatment 1339880.0 250000.0 1.22 1279810.0 199000.0 1.18 1021040.0 43160.78125 0.247203047501593 1.5303 0.891 1188 NINDS_000575 NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M18 compound treatment 1178340.0 88400.0 0.43 1208350.0 127000.0 0.76 939370.0 -38509.21875 -0.220561258536197 0.5592 0.6219 1189 NINDS_000576 CO[C@]1(NC(=O)Cc2cccs2)[C@H]3SCC(=C(N3C1=O)C(=O)O)COC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M19 compound treatment 1029830.0 -60100.0 -0.29 1029050.0 -52000.0 -0.31 932840.0 -45039.21875 -0.257961784046504 -0.4968 -0.9972 1190 NINDS_000577 Nc1c2C(O)CCCc2nc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M20 compound treatment 147730.0 -942000.0 -4.6 132980.0 -948000.0 -5.64 98720.0 -879159.21875 -5.03537776240136 -8.8198 -0.9965 1191 NINDS_000578 Oc1c(Cl)cc(Cl)c2cccnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M21 compound treatment 1242670.0 153000.0 0.75 1254670.0 174000.0 1.03 935710.0 -42169.21875 -0.241523880797716 0.8876 0.6845 1192 NINDS_000579 Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M22 compound treatment 1198580.0 109000.0 0.53 1136740.0 55700.0 0.33 1098400.0 120520.78125 0.690281861204096 0.8964 0.962 1193 NINDS_000580 CCOc1ccc(NC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M23 mock treatment 1037060.0 -52900.0 -0.26 1141210.0 60200.0 0.36 948680.0 -29199.21875 -0.167238304095009 -0.039 -0.0826 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 M24 mock treatment 982780.0 -107000.0 -0.52 1055200.0 -25800.0 -0.15 935250.0 -42629.21875 -0.244158527311459 -0.5318 -0.8898 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N01 mock treatment 1170880.0 81000.0 0.4 1146040.0 65000.0 0.39 910670.0 -67209.21875 -0.384940291024069 0.2294 0.3404 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N02 mock treatment 1128490.0 38600.0 0.19 1118430.0 37400.0 0.22 965950.0 -11929.21875 -0.0683245099812261 0.1978 0.6605 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N03 compound treatment 1351420.0 261000.0 1.28 1098530.0 17500.0 0.1 890100.0 -87779.21875 -0.502754810127747 0.5075 0.3686 41 NINDS_000581 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N04 compound treatment 1327370.0 237000.0 1.16 1367410.0 286000.0 1.7 996200.0 18320.78125 0.104932135759476 1.7137 0.8305 1194 NINDS_000582 CC(=O)N=c1sc(nn1C)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N05 compound treatment 1245220.0 155000.0 0.76 1215220.0 134000.0 0.8 975100.0 -2779.21875 -0.015917954327427 0.8896 0.8078 1195 NINDS_000583 C[C@@]12CCC3C(CC[C@]4(O)C[C@@H](O)CC[C@]34C=O)[C@@]2(O)CCC1C5=CC(=O)OC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N06 compound treatment 1107380.0 17500.0 0.09 1095210.0 14200.0 0.08 884760.0 -93119.21875 -0.533339619656849 -0.2099 -0.384 1196 NINDS_000584 CCCOc1ccccc1c2nc3[nH]nnc3c(=O)[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N07 compound treatment 1152660.0 62700.0 0.31 1027360.0 -53700.0 -0.32 807840.0 -170039.21875 -0.973898336694033 -0.5695 -0.5324 3174345 NINDS_000585 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@@H]3C(=C)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N.OC(=O)c1cc(ccc1O)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N08 compound treatment 748800.0 -341000.0 -1.67 710880.0 -370000.0 -2.2 533410.0 -444469.21875 -2.54569408183852 -3.7028 -0.986 1198 NINDS_000586 Cn1cnc([N+](=O)[O-])c1Sc2[nH]cnc3ncnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N09 compound treatment 1179210.0 89300.0 0.44 1269760.0 189000.0 1.12 939240.0 -38639.21875 -0.22130583255095 0.7721 0.6306 1199 NINDS_000587 CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N10 compound treatment 1244020.0 154000.0 0.75 1161450.0 80400.0 0.48 948400.0 -29479.21875 -0.168842001972939 0.6134 0.6756 1200 NINDS_000588 NC1C[C@H]1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N11 compound treatment 1377290.0 287000.0 1.4 1312500.0 231000.0 1.38 926940.0 -50939.21875 -0.291753989331467 1.4369 0.7229 1201 NINDS_000589 COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N12 compound treatment 1156700.0 66800.0 0.33 1123770.0 42800.0 0.25 932580.0 -45299.21875 -0.259450932076011 0.1854 0.3796 1202 NINDS_000590 COc1ccc2CN(C)CC[C@]34C=C[C@H](O)C[C@@H]4Oc1c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N13 compound treatment 1202240.0 112000.0 0.55 1078270.0 -2740.0 -0.02 891920.0 -85959.21875 -0.492330773921199 0.0232 0.0314 1203 NINDS_000591 CN(C)[C@H]1[C@@H]2[C@@H](O)[C@@H]3C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N14 compound treatment 1063250.0 -26700.0 -0.13 1020960.0 -60100.0 -0.36 897650.0 -80229.21875 -0.459512242347836 -0.5467 -0.9167 1204 NINDS_000592 CN1C[C@@H](C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34)C(=O)N[C@]5(C)O[C@@]6(O)[C@@H]7CCCN7C(=O)[C@H](Cc8ccccc8)N6C5=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N15 compound treatment 1340670.0 251000.0 1.23 1165230.0 84200.0 0.5 991320.0 13440.78125 0.0769819727441164 1.0409 0.7851 818 NINDS_000593 CCC1(CC)C(=O)NC=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N16 compound treatment 1039130.0 -50800.0 -0.25 948550.0 -132000.0 -0.79 876180.0 -101699.21875 -0.582481504630576 -0.9344 -0.9245 1205 NINDS_000594 CC(=CCC1=C(O)C(=O)c2ccccc2C1=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N17 compound treatment 1233480.0 144000.0 0.7 1392190.0 311000.0 1.85 1018400.0 40520.78125 0.232082467509677 1.6073 0.8067 1206 NINDS_000595 CC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N18 compound treatment 1257290.0 167000.0 0.82 997630.0 -83400.0 -0.5 862320.0 -115559.21875 -0.661864549588134 -0.1963 -0.1688 1207 NINDS_000596 CN(C)CCC(c1ccc(Cl)cc1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N19 compound treatment 1060960.0 -29000.0 -0.14 1190690.0 110000.0 0.65 968000.0 -9879.21875 -0.0565831505178067 0.2622 0.3914 1208 NINDS_000597 CNC[C@H](O)c1cccc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N20 compound treatment 1050240.0 -39700.0 -0.19 1204590.0 124000.0 0.73 945720.0 -32159.21875 -0.184191681661702 0.206 0.2634 1209 NINDS_000598 CC(C(=O)O)c1cccc(c1)C(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N21 compound treatment 1106590.0 16700.0 0.08 1290560.0 210000.0 1.25 1017310.0 39430.78125 0.225839500770591 0.8968 0.7067 1210 NINDS_000599 CC(C)(C)c1cc(SC(C)(C)Sc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N22 compound treatment 1091850.0 1930.0 0.01 1120960.0 39900.0 0.24 1052750.0 74870.78125 0.428821832177218 0.3902 0.7957 1211 NINDS_000600 CON 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N23 mock treatment 1256670.0 167000.0 0.81 1152030.0 71000.0 0.42 940900.0 -36979.21875 -0.211798195131791 0.5919 0.6285 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 N24 mock treatment 1118910.0 29000.0 0.14 1011140.0 -69900.0 -0.42 931290.0 -46589.21875 -0.266839397299333 -0.3122 -0.6077 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O01 mock treatment 964060.0 -126000.0 -0.61 1034930.0 -46100.0 -0.27 790670.0 -187209.21875 -1.0722393815657 -1.1323 -0.8943 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O02 mock treatment 1307860.0 218000.0 1.06 1298950.0 218000.0 1.3 1040030.0 62150.78125 0.355968128579805 1.5685 0.9148 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O03 compound treatment 1121540.0 31600.0 0.15 1043220.0 -37800.0 -0.22 795430.0 -182449.21875 -1.04497651764088 -0.6439 -0.5962 1212 NINDS_000601 CC/1=C(CC(=O)O)c2cc(F)ccc2\C1=C/c3ccc(cc3)S(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O04 compound treatment 1402360.0 312000.0 1.53 1262930.0 182000.0 1.08 949670.0 -28209.21875 -0.16156808659804 1.4126 0.7522 1213 NINDS_000602 CNCCc1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O05 compound treatment 1217360.0 127000.0 0.62 1087400.0 6390.0 0.04 894240.0 -83639.21875 -0.479042991504061 0.1048 0.1333 1214 NINDS_000603 CCOC(=O)Nc1c[n+](no1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O06 compound treatment 58880.0 -1030000.0 -5.04 36770.0 -1040000.0 -6.21 39680.0 -938199.21875 -5.37352891494784 -9.596 -0.9961 1215 NINDS_000604 CC(NCCC(c1ccccc1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O07 compound treatment 1095710.0 5790.0 0.03 1133200.0 52200.0 0.31 950970.0 -26909.21875 -0.154122346450506 0.1065 0.3064 1216 NINDS_000605 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2C[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O08 compound treatment 863870.0 -226000.0 -1.1 1140400.0 59400.0 0.35 935310.0 -42569.21875 -0.243814877766188 -0.5745 -0.4849 1000127 NINDS_000606 CC1(C)O[C@@H]2CC3C4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O09 compound treatment 1179210.0 89300.0 0.44 1016960.0 -64100.0 -0.38 793920.0 -183959.21875 -1.05362503119686 -0.5764 -0.4794 1218 NINDS_000607 CCCCNc1ccc(cc1)C(=O)OCCN(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O10 compound treatment 1093520.0 3600.0 0.02 1037130.0 -43900.0 -0.26 941920.0 -35959.21875 -0.205956152862187 -0.2594 -0.7793 1219 NINDS_000608 CC[C@@]12CCC3C(CCC4=CC(=O)CC[C@H]34)C2CC[C@@]1(O)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O11 compound treatment 1332320.0 242000.0 1.18 1225440.0 144000.0 0.86 875040.0 -102839.21875 -0.589010845990721 0.8396 0.5324 1220 NINDS_000609 CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O12 compound treatment 1286310.0 196000.0 0.96 1244640.0 164000.0 0.97 1066650.0 88770.78125 0.508433976831623 1.4093 0.9666 1221 NINDS_000610 CN(C)CCOC(=O)C(c1ccccc1)C2(O)CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O13 compound treatment 1239680.0 150000.0 0.73 1226210.0 145000.0 0.86 941360.0 -36519.21875 -0.209163548618048 0.8002 0.6952 1222 NINDS_000611 Cn1cnc2n(C)c(=O)[nH]c(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O14 compound treatment 1061020.0 -28900.0 -0.14 1189130.0 108000.0 0.64 894350.0 -83529.21875 -0.478412967337731 0.0135 0.0165 1223 NINDS_000612 CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O15 compound treatment 233570.0 -856000.0 -4.18 226160.0 -855000.0 -5.08 246580.0 -731299.21875 -4.18851073300565 -7.7688 -0.9956 1224 NINDS_000613 C[C@@]12CCC3C(CCc4cc(O)ccc34)C2CC[C@@H]1OC(=O)CCC5CCCC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O16 compound treatment 903710.0 -186000.0 -0.91 805240.0 -276000.0 -1.64 742350.0 -235529.21875 -1.34899181535713 -2.2509 -0.9744 1225 NINDS_000614 Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O17 compound treatment 1115600.0 25700.0 0.13 1030170.0 -50800.0 -0.3 947200.0 -30679.21875 -0.175714992878355 -0.2036 -0.548 3046099 NINDS_000615 NC[C@@H]1O[C@H](OC2[C@@H](O)[C@H](O[C@@H]3[C@H](N)[C@@H](O)C[C@H](N)[C@H]3O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O18 compound treatment 1077440.0 -12500.0 -0.06 1154990.0 74000.0 0.44 967650.0 -10229.21875 -0.0585877728652197 0.1849 0.4129 1227 NINDS_000616 NCCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O19 compound treatment 55040.0 -1030000.0 -5.06 39040.0 -1040000.0 -6.2 44040.0 -933839.21875 -5.34855704799149 -9.5846 -0.9962 1228 NINDS_000617 CC[Hg]Sc1ccccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O20 compound treatment 62270.0 -1030000.0 -5.02 39300.0 -1040000.0 -6.19 41030.0 -936849.21875 -5.36579680017925 -9.5732 -0.9961 28 NINDS_000618 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O21 compound treatment 1168750.0 78800.0 0.39 1085970.0 4960.0 0.03 952480.0 -25399.21875 -0.145473832894524 0.1554 0.3765 121 NINDS_000619 OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O22 compound treatment 1171770.0 81800.0 0.4 1128410.0 47400.0 0.28 987520.0 9640.78125 0.0552175015436315 0.4255 0.8642 1229 NINDS_000620 CC(=O)N[C@H]1[C@@H](O)C[C@](O)(O[C@@H]1C(O)[C@H](O)CO)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O23 mock treatment 1230100.0 140000.0 0.68 1264030.0 183000.0 1.09 1069820.0 91940.78125 0.526590127806765 1.3278 0.9556 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 O24 mock treatment 926750.0 -163000.0 -0.8 1106690.0 25700.0 0.15 834500.0 -143379.21875 -0.821203388745368 -0.8462 -0.7329 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P01 mock treatment 1051440.0 -38500.0 -0.19 876750.0 -204000.0 -1.21 828080.0 -149799.21875 -0.857973890089345 -1.3052 -0.8707 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P02 mock treatment 1148260.0 58300.0 0.29 1096100.0 15100.0 0.09 1029160.0 51280.78125 0.293710285961576 0.3859 0.9211 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P03 compound treatment 864600.0 -225000.0 -1.1 880360.0 -201000.0 -1.19 881200.0 -96679.21875 -0.553729492676251 -1.6442 -0.9585 1000128 NINDS_000621 CCCCC(=O)OC1(C(C)CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC21C)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P04 compound treatment 1151940.0 62000.0 0.3 1121240.0 40200.0 0.24 924700.0 -53179.21875 -0.304583572354911 0.1372 0.279 1231 NINDS_000622 CC(C)C[C@H](NC(=O)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P05 compound treatment 1111270.0 21300.0 0.1 1089560.0 8550.0 0.05 831560.0 -146319.21875 -0.838042216463638 -0.3943 -0.466 1232 NINDS_000623 OC1=C(O)C(=O)C(=C(O)C1=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P06 compound treatment 66300.0 -1020000.0 -5.0 45650.0 -1040000.0 -6.16 61940.0 -915939.21875 -5.24603493365237 -9.4709 -0.9959 436 NINDS_000624 CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P07 compound treatment 1307040.0 217000.0 1.06 1056710.0 -24300.0 -0.14 913120.0 -64759.21875 -0.370907934592178 0.3149 0.2779 1233 NINDS_000625 CO[C@@H]1[C@@H](O)[C@H](C)O[C@H](O[C@H]2CC[C@@]3(C=O)[C@H](CCC4C3CC[C@]5(C)[C@H](CC[C@]45O)C6=CC(=O)OC6)C2)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P08 compound treatment 1082100.0 -7820.0 -0.04 1047250.0 -33800.0 -0.2 895520.0 -82359.21875 -0.47171180120495 -0.4103 -0.7982 1234 NINDS_000626 C[C@H]1CC2C3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P09 compound treatment 1139010.0 49100.0 0.24 1108650.0 27600.0 0.16 996250.0 18370.78125 0.105218510380535 0.2941 0.9512 1235 NINDS_000627 CCOC(=O)CCCCCCCCCCCCC1CCC=C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P10 compound treatment 1146010.0 56100.0 0.27 1084230.0 3220.0 0.02 861550.0 -116329.21875 -0.666274718752442 -0.2154 -0.2989 1236 NINDS_000628 OCc1cc2c(cn1)[nH]c3ccccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P11 compound treatment 1208850.0 119000.0 0.58 1206150.0 125000.0 0.74 918690.0 -59189.21875 -0.339005801806204 0.5694 0.5676 1237 NINDS_000629 CC(=O)Nc1ccc(OC(=O)c2ccccc2O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P12 compound treatment 450520.0 -639000.0 -3.12 398890.0 -682000.0 -4.06 401310.0 -576569.21875 -3.30229583067643 -6.0521 -0.9934 1238 NINDS_000630 Oc1c(Cl)cc(Cl)c(Cl)c1Cc2c(O)c(Cl)cc(Cl)c2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P13 compound treatment 1195460.0 106000.0 0.52 1127530.0 46500.0 0.28 1047360.0 69480.78125 0.397950648027057 0.6872 0.9711 1239 NINDS_000631 C1CCN2C[C@H]3C[C@H](CN4CCCC[C@H]34)[C@@H]2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P14 compound treatment 549310.0 -541000.0 -2.64 555680.0 -525000.0 -3.12 457120.0 -520759.21875 -2.98264447865036 -5.0506 -0.9976 1240 NINDS_000632 CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P15 compound treatment 1121380.0 31500.0 0.15 1173070.0 92100.0 0.55 1024890.0 47010.78125 0.269253893323137 0.5602 0.8905 1241 NINDS_000633 NC(=N)NS(=O)(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P16 compound treatment 1006300.0 -83600.0 -0.41 1074410.0 -6600.0 -0.04 893180.0 -84699.21875 -0.485114133470512 -0.5386 -0.8476 1242 NINDS_000634 CN(CS(=O)(=O)O)c1c(C)n(C)n(c2ccccc2)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P17 compound treatment 895000.0 -195000.0 -0.95 865180.0 -216000.0 -1.28 799280.0 -178599.21875 -1.02292567181934 -1.8814 -0.9915 1243 NINDS_000635 OC[C@H]1OC(C[C@H]1O)n2cc(F)c(=O)[nH]c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P18 compound treatment 1104240.0 14300.0 0.07 1172250.0 91200.0 0.54 903170.0 -74709.21875 -0.427896484182921 0.1066 0.1535 1244 NINDS_000636 C[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P19 compound treatment 890160.0 -200000.0 -0.98 994760.0 -86300.0 -0.51 895740.0 -82139.21875 -0.47045175287229 -1.1312 -0.9437 3046112 NINDS_000637 CC1(C)O[C@@H]2CC3C4CCC5=CC(=O)CCC5(C)C4(F)C(O)CC3(C)[C@@]2(O1)C(=O)CCl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P20 compound treatment 1095470.0 5550.0 0.03 1255630.0 175000.0 1.04 962850.0 -15029.21875 -0.0860797364868848 0.5655 0.5425 1246 NINDS_000638 CC[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P21 compound treatment 787610.0 -302000.0 -1.48 746430.0 -335000.0 -1.99 673370.0 -304509.21875 -1.74407424257014 -3.0084 -0.9928 1247 NINDS_000639 Oc1c(Cl)cc(Cl)cc1Sc2cc(Cl)cc(Cl)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P22 compound treatment 993450.0 -96500.0 -0.47 972040.0 -109000.0 -0.65 890560.0 -87319.21875 -0.500120163614004 -0.935 -0.9899 1000060 NINDS_000640 COC(=O)C1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P23 mock treatment 1060840.0 -29100.0 -0.14 1227730.0 147000.0 0.87 1135710.0 157830.78125 0.90397460343833 0.9436 0.7463 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.501 P24 mock treatment 999630.0 -90300.0 -0.44 838510.0 -243000.0 -1.44 924190.0 -53689.21875 -0.307504593489713 -1.2648 -0.8218 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A01 mock treatment 865710.0 -197000.0 -0.96 767840.0 -281000.0 -1.67 760010.0 -208113.125 -1.19196634618563 -2.2099 -0.974 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A02 mock treatment 844450.0 -218000.0 -1.07 942330.0 -107000.0 -0.64 813030.0 -155093.125 -0.888294698014658 -1.4955 -0.9798 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A03 compound treatment 860640.0 -202000.0 -0.99 863130.0 -186000.0 -1.11 854400.0 -113723.125 -0.651348336550432 -1.585 -0.9785 1248 NINDS_000641 C[C@@]12CCC3C(CCc4cc(OC(=O)CCC(=O)O)ccc34)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A04 compound treatment 951860.0 -111000.0 -0.54 866400.0 -183000.0 -1.09 861400.0 -106723.125 -0.611255889602171 -1.2933 -0.951 1249 NINDS_000642 C[N+](C)(C)CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A05 compound treatment 826410.0 -236000.0 -1.15 836410.0 -213000.0 -1.27 863470.0 -104653.125 -0.599399980290327 -1.7433 -0.9605 1250 NINDS_000643 COc1cc(C)c2c(=O)cc(oc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A06 compound treatment 737130.0 -325000.0 -1.59 730260.0 -319000.0 -1.9 793130.0 -174993.125 -1.00227179719615 -2.5922 -0.9706 1251 NINDS_000644 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(oc4cc(O)cc(O)c4c3=O)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A07 compound treatment 927140.0 -135000.0 -0.66 964860.0 -84500.0 -0.5 923200.0 -44923.125 -0.257296857973232 -0.8206 -0.9435 1252 NINDS_000645 CC(C)NCC(O)c1cc(O)cc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A08 compound treatment 933870.0 -129000.0 -0.63 831680.0 -218000.0 -1.29 863950.0 -104173.125 -0.596650783928161 -1.4548 -0.9339 1253 NINDS_000646 C[C@H]1OC=C2C(=C(C(=O)O)C(=O)C(=C2[C@@H]1C)C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A09 compound treatment 810440.0 -252000.0 -1.23 833450.0 -216000.0 -1.28 846050.0 -122073.125 -0.699172898267287 -1.8561 -0.9709 1254 NINDS_000647 O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A10 compound treatment 920610.0 -142000.0 -0.69 890580.0 -159000.0 -0.94 956420.0 -11703.125 -0.0670295597416249 -0.9842 -0.8388 1255 NINDS_000648 NC(=O)c1ccc(cc1Cl)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A11 compound treatment 914880.0 -148000.0 -0.72 967840.0 -81500.0 -0.48 1021440.0 53316.875 0.305371997483514 -0.5201 -0.5645 1256 NINDS_000649 Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A12 compound treatment 866600.0 -196000.0 -0.96 873320.0 -176000.0 -1.05 966370.0 -1753.125 -0.0100410101508816 -1.1629 -0.8198 1257 NINDS_000650 CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A13 compound treatment 876970.0 -186000.0 -0.91 909670.0 -140000.0 -0.83 985510.0 17386.875 0.099583194790508 -0.9456 -0.7664 1258 NINDS_000651 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCNCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A14 compound treatment 330420.0 -732000.0 -3.58 302320.0 -747000.0 -4.44 347840.0 -620283.125 -3.55266689742349 -6.6811 -0.9943 1259 NINDS_000652 CCc1nc(N)nc(N)c1c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A15 compound treatment 697600.0 -365000.0 -1.78 693990.0 -355000.0 -2.11 725500.0 -242623.125 -1.38962210964056 -3.0518 -0.9862 1260 NINDS_000653 N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A16 compound treatment 828980.0 -234000.0 -1.14 747000.0 -302000.0 -1.8 929000.0 -39123.125 -0.224077401930387 -1.8263 -0.8529 1261 NINDS_000654 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A17 compound treatment 990960.0 -71600.0 -0.35 900640.0 -149000.0 -0.88 1066810.0 98686.875 0.565228328632461 -0.3862 -0.3491 1262 NINDS_000655 NC[C@H]1CC[C@@H](CC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A18 compound treatment 686780.0 -376000.0 -1.84 736550.0 -313000.0 -1.86 836580.0 -131543.125 -0.753412251495864 -2.5689 -0.9445 1263 NINDS_000656 C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A19 compound treatment 874580.0 -188000.0 -0.92 869460.0 -180000.0 -1.07 960880.0 -7243.125 -0.0414849435431611 -1.1718 -0.8308 1264 NINDS_000657 OCc1ccccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A20 compound treatment 895370.0 -167000.0 -0.82 848180.0 -201000.0 -1.2 1115300.0 147176.875 0.84295443613549 -0.6756 -0.4031 1265 NINDS_000658 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A21 compound treatment 868390.0 -194000.0 -0.95 874330.0 -175000.0 -1.04 982830.0 14706.875 0.084233515101745 -1.1 -0.7797 1266 NINDS_000659 CCn1cc(C(=O)O)c(=O)c2cc3OCOc3cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A22 compound treatment 915370.0 -147000.0 -0.72 867450.0 -182000.0 -1.08 966420.0 -1703.125 -0.00975463552982258 -1.0453 -0.8048 1267 NINDS_000660 CC(=O)Nc1ccc(O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A23 mock treatment 841890.0 -221000.0 -1.08 849950.0 -199000.0 -1.19 909870.0 -58253.125 -0.333644331947565 -1.4997 -0.9161 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 A24 mock treatment 807860.0 -255000.0 -1.24 798620.0 -251000.0 -1.49 985280.0 17156.875 0.0982658715336366 -1.5225 -0.783 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B01 mock treatment 908040.0 -155000.0 -0.76 867450.0 -182000.0 -1.08 991680.0 23556.875 0.13492182302919 -0.9825 -0.741 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B02 mock treatment 953920.0 -109000.0 -0.53 998970.0 -50300.0 -0.3 866300.0 -101823.125 -0.583191176738388 -0.8161 -0.9674 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B03 compound treatment 989290.0 -73300.0 -0.36 983720.0 -65600.0 -0.39 1039040.0 70916.875 0.406175864096286 -0.1975 -0.2959 1268 NINDS_000661 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3cc(C)on3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B04 compound treatment 989980.0 -72600.0 -0.35 912480.0 -137000.0 -0.81 948120.0 -20003.125 -0.114567746837421 -0.7408 -0.8276 1269 NINDS_000662 CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B05 compound treatment 971920.0 -90700.0 -0.44 960750.0 -88600.0 -0.53 964110.0 -4013.125 -0.0229851430227489 -0.5731 -0.8323 1270 NINDS_000663 C[N+](C)(C)CCCCCC[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B06 compound treatment 1030760.0 -31800.0 -0.16 918210.0 -131000.0 -0.78 964000.0 -4123.125 -0.0236151671890787 -0.5536 -0.696 1271 NINDS_000664 CC(=O)OC(CC(=O)O)[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B07 compound treatment 577240.0 -485000.0 -2.37 549760.0 -500000.0 -2.97 652480.0 -315643.125 -1.80784360623514 -4.128 -0.9807 1272 NINDS_000665 Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B08 compound treatment 910660.0 -152000.0 -0.74 947550.0 -102000.0 -0.61 1034890.0 66766.875 0.382406770548388 -0.5572 -0.5403 1273 NINDS_000666 C[C@@]12CC(=O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B09 compound treatment 963540.0 -99100.0 -0.48 900160.0 -149000.0 -0.89 1053920.0 85796.875 0.491400951323448 -0.5078 -0.452 1274 NINDS_000667 C1CN2C[C@@H](N=C2S1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B10 compound treatment 886470.0 -176000.0 -0.86 919120.0 -130000.0 -0.77 938970.0 -29153.125 -0.16697430249122 -1.0402 -0.8894 1275 NINDS_000668 CC(=O)NCCc1c[nH]c2ccc(O)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B11 compound treatment 903120.0 -159000.0 -0.78 931930.0 -117000.0 -0.7 1012960.0 44836.875 0.256802861751905 -0.7046 -0.6541 1000129 NINDS_000669 CC1(C)[C@H](CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O)OC(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B12 compound treatment 977020.0 -85600.0 -0.42 947360.0 -102000.0 -0.61 1108570.0 140446.875 0.804408412140947 -0.127 -0.1165 1277 NINDS_000670 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]2C[C@H](O)[C@H](O[C@H]3C[C@H](OC(=O)C)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](C)O3)[C@@H](C)O2)O[C@H]5CC[C@@]6(C)C(CCC7C6C[C@@H](O)[C@]8(C)[C@H](CC[C@]78O)C9=CC(=O)OC9)C5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B13 compound treatment 972900.0 -89700.0 -0.44 916740.0 -133000.0 -0.79 997670.0 29546.875 0.16922950263206 -0.6105 -0.6652 1278 NINDS_000671 COc1ccc(cc1O)c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@H](C)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B14 compound treatment 237440.0 -825000.0 -4.03 237820.0 -811000.0 -4.83 272100.0 -696023.125 -3.98646717340368 -7.4153 -0.996 1279 NINDS_000672 N[C@@H]([C@@H]1CC(=NO1)Cl)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B15 compound treatment 916910.0 -146000.0 -0.71 973340.0 -76000.0 -0.45 1067900.0 99776.875 0.571471295371547 -0.3419 -0.3357 1280 NINDS_000673 NCCNC(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B16 compound treatment 999700.0 -62900.0 -0.31 985770.0 -63500.0 -0.38 1152640.0 184516.875 1.05681900314236 0.2146 0.1844 3174477 NINDS_000674 CN[C@H](CC(C)C)C(=O)NC1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]6CC(=O)C(NC(=O)[C@@H]4NC(=O)[C@H](CC(=O)N)NC1=O)c7ccc(O)c(c7)-c8c(O)cc(O)cc8[C@@H](NC6=O)C(=O)O)c3O[C@@H]9OC(CO)[C@@H](O)[C@H](O)[C@H]9O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B17 compound treatment 918360.0 -144000.0 -0.7 925360.0 -124000.0 -0.74 1036880.0 68756.875 0.393804480466537 -0.6051 -0.5535 1282 NINDS_000675 NS(=O)(=O)c1cc2c(N=CNS2(=O)=O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B18 compound treatment 554960.0 -508000.0 -2.48 481760.0 -568000.0 -3.38 495890.0 -472233.125 -2.70471164446776 -4.9421 -0.9912 3046211 NINDS_000676 CCC(C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C/C=C(\C)/[C@@H](OC4C[C@H](OC)C(O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C/6\CO[C@@H]7[C@H](O)C(=C[C@@H](C(=O)O3)[C@@]76O)C)O2)C=C[C@@H]1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B19 compound treatment 721460.0 -341000.0 -1.67 738830.0 -310000.0 -1.85 992930.0 24806.875 0.142081188555665 -1.9462 -0.7812 1284 NINDS_000677 OC(=O)CN(CC(=O)O)Cc1cc2c(c3ccccc3C(=O)O)c4cc(CN(CC(=O)O)CC(=O)O)c(=O)cc4oc2cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B20 compound treatment 76350.0 -986000.0 -4.82 78290.0 -971000.0 -5.77 109720.0 -858403.125 -4.91649739275493 -8.9544 -0.9966 1285 NINDS_000678 CC[C@@]1(O)C[C@H](OC2CC(C(OC3CC(O)C(OC4CCC(=O)C(C)O4)C(C)O3)C(C)O2)N(C)C)c5c(O)c6C(=O)c7c(O)cccc7C(=O)c6cc5[C@H]1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B21 compound treatment 138480.0 -924000.0 -4.52 109560.0 -940000.0 -5.59 179740.0 -788383.125 -4.51545837342389 -8.4402 -0.9947 1286 NINDS_000679 Cc1cc(ccc1OCCOCC[N+](C)(C)Cc2ccccc2)C(C)(C)CC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B22 compound treatment 916480.0 -146000.0 -0.71 894880.0 -154000.0 -0.92 1146720.0 178596.875 1.02291224800897 -0.3518 -0.2271 1287 NINDS_000680 CC(=O)C1CCC2C3CC=C4CC(CC[C@]4(C)C3CC[C@]12C)OS(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B23 mock treatment 904750.0 -158000.0 -0.77 1027370.0 -21900.0 -0.13 1088330.0 120206.875 0.68848396553626 -0.1231 -0.1181 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 B24 mock treatment 858980.0 -204000.0 -0.99 958200.0 -91100.0 -0.54 1068480.0 100356.875 0.574793240975832 -0.5553 -0.4372 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C01 mock treatment 984290.0 -78300.0 -0.38 909290.0 -140000.0 -0.83 909600.0 -58523.125 -0.335190754901283 -0.8952 -0.9174 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C02 mock treatment 1018440.0 -44200.0 -0.22 895260.0 -154000.0 -0.92 886170.0 -81953.125 -0.469385902329536 -0.9245 -0.879 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C03 compound treatment 66250.0 -996000.0 -4.87 57120.0 -992000.0 -5.9 74930.0 -893193.125 -5.11575685408779 -9.1706 -0.9966 1288 NINDS_000681 CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O)[C@H](C)O2)N(C)C)c3c(O)c4C(=O)c5c(O)cccc5C(=O)c4cc3[C@H]1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C04 compound treatment 454900.0 -608000.0 -2.97 452920.0 -596000.0 -3.55 451040.0 -517083.125 -2.96158967955769 -5.4717 -0.9963 1289 NINDS_000682 C[C@@]12C[C@H](O)C3C(CCC4=CC(=O)C=C[C@]34C)C2CC[C@]1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C05 compound treatment 1019270.0 -43300.0 -0.21 1072320.0 23000.0 0.14 1040170.0 72046.875 0.41264793053222 0.195 0.4033 1290 NINDS_000683 OC(=O)c1ccc(cc1)S(=O)(=O)N(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C06 compound treatment 1031630.0 -31000.0 -0.15 974260.0 -75100.0 -0.45 957280.0 -10843.125 -0.0621039162594099 -0.3809 -0.8013 1291 NINDS_000684 CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C07 compound treatment 961440.0 -101000.0 -0.49 1195600.0 146000.0 0.87 1167220.0 199096.875 1.14032584264317 0.8752 0.577 1292 NINDS_000685 O=c1[nH]cnc2[nH]ncc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C08 compound treatment 1023920.0 -38700.0 -0.19 994270.0 -55000.0 -0.33 1048690.0 80566.875 0.461446165960675 -0.0317 -0.0531 1293 NINDS_000686 CC(=O)OCC[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C09 compound treatment 381780.0 -681000.0 -3.33 390080.0 -659000.0 -3.92 400320.0 -567803.125 -3.25208809515995 -6.0614 -0.9964 1294 NINDS_000687 CCN(CC)Cc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C10 compound treatment 763040.0 -300000.0 -1.46 762010.0 -287000.0 -1.71 801990.0 -166133.125 -0.951526214344488 -2.3808 -0.9747 1295 NINDS_000688 OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C11 compound treatment 926830.0 -136000.0 -0.66 1145830.0 96500.0 0.57 1230190.0 262066.875 1.50098604040489 0.815 0.4688 2550 NINDS_000689 O[C@@H]([C@@H](COC(=O)CCC(=O)O)NC(=O)C(Cl)Cl)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C12 compound treatment 995110.0 -67500.0 -0.33 942530.0 -107000.0 -0.64 1007110.0 38986.875 0.223297031088001 -0.4281 -0.5711 1000131 NINDS_000690 C1CCN2CC3C[C@@H](CN4CCCC[C@H]34)[C@@H]2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C13 compound treatment 868640.0 -194000.0 -0.95 805310.0 -244000.0 -1.45 956290.0 -11833.125 -0.0677741337563783 -1.424 -0.821 3174481 NINDS_000691 CNC[C@@H](O)c1ccc(O)c(O)c1.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C14 compound treatment 968480.0 -94100.0 -0.46 948390.0 -101000.0 -0.6 1115730.0 147606.875 0.845417257876598 -0.1239 -0.1092 1297 NINDS_000692 COc1cc(CC=C)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C15 compound treatment 1019170.0 -43400.0 -0.21 1005800.0 -43500.0 -0.26 1049720.0 81596.875 0.467345483154491 -0.0021 -0.0036 1298 NINDS_000693 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C16 compound treatment 941670.0 -121000.0 -0.59 942270.0 -107000.0 -0.64 1024330.0 56206.875 0.321924450580725 -0.5228 -0.5644 1299 NINDS_000694 Nc1ccc(cc1)C(=O)NCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C17 compound treatment 980600.0 -82000.0 -0.4 987960.0 -61400.0 -0.36 1007620.0 39496.875 0.226218052222803 -0.3113 -0.5302 1300 NINDS_000695 OC(=O)c1cccnc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C18 compound treatment 797310.0 -265000.0 -1.3 770370.0 -279000.0 -1.66 855480.0 -112643.125 -0.645162644735558 -2.0785 -0.944 1301 NINDS_000696 OCCN(CCO)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCO)CCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C19 compound treatment 790580.0 -272000.0 -1.33 862750.0 -187000.0 -1.11 891910.0 -76213.125 -0.436510095831962 -1.6599 -0.9297 1302 NINDS_000697 CC(C)CC1N2C(=O)[C@](NC(=O)C3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(OC2(O)[C@@H]7CCCN7C1=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C20 compound treatment 906980.0 -156000.0 -0.76 950420.0 -98900.0 -0.59 1104320.0 136196.875 0.780066569350931 -0.3281 -0.2651 1303 NINDS_000698 C[N+]1(CCC2CC1)CC2OC(=O)C(O)(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C21 compound treatment 910560.0 -152000.0 -0.74 892030.0 -157000.0 -0.94 1150570.0 182446.875 1.04496309383052 -0.3656 -0.2304 1304 NINDS_000699 ClC1=C(Cl)C2(Cl)C3C4CC(C5OC54)C3C1(Cl)C2(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C22 compound treatment 991680.0 -70900.0 -0.35 941530.0 -108000.0 -0.64 1075560.0 107436.875 0.615343887317788 -0.2148 -0.2253 1305 NINDS_000700 CCOC(=O)O[C@H]([C@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccc(OC)cc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C23 mock treatment 987520.0 -75100.0 -0.37 886370.0 -163000.0 -0.97 1014970.0 46846.875 0.268315121518478 -0.6163 -0.5758 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 C24 mock treatment 864050.0 -199000.0 -0.97 915970.0 -133000.0 -0.79 888990.0 -79133.125 -0.453234373701808 -1.2796 -0.9604 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D01 mock treatment 1076890.0 14300.0 0.07 971450.0 -77900.0 -0.46 914410.0 -53713.125 -0.307641516355406 -0.4046 -0.7222 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D02 mock treatment 1113560.0 51000.0 0.25 981310.0 -68000.0 -0.4 1001050.0 32926.875 0.188588427015649 0.0192 0.0375 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D03 compound treatment 890720.0 -172000.0 -0.84 906400.0 -143000.0 -0.85 900800.0 -67323.125 -0.385592688207669 -1.1981 -0.9543 3046265 NINDS_000701 Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D04 compound treatment 772760.0 -290000.0 -1.42 715520.0 -334000.0 -1.98 737280.0 -230843.125 -1.32215224891906 -2.7269 -0.9831 935 NINDS_000702 CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D05 compound treatment 721570.0 -341000.0 -1.67 758480.0 -291000.0 -1.73 839690.0 -128433.125 -0.735599750065993 -2.3852 -0.9496 1307 NINDS_000703 ClC(Cl)C(c1ccc(Cl)cc1)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D06 compound treatment 414180.0 -648000.0 -3.17 470620.0 -579000.0 -3.44 449520.0 -518603.125 -2.97029546803788 -5.5308 -0.9982 1308 NINDS_000704 CCCSc1ccc2nc(NC(=O)OC)[nH]c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D07 compound treatment 173950.0 -889000.0 -4.34 191930.0 -857000.0 -5.1 194110.0 -774013.125 -4.43315430733153 -8.0098 -0.9974 3046268 NINDS_000705 Cc1cc(C2CCCCC2)n(O)c(=O)c1.NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D08 compound treatment 587370.0 -475000.0 -2.32 572120.0 -477000.0 -2.84 566560.0 -401563.125 -2.29994975506295 -4.3068 -0.995 1310 NINDS_000706 NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@H]([C@H](OP(=O)(O)O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D09 compound treatment 944220.0 -118000.0 -0.58 1002690.0 -46600.0 -0.28 1051860.0 83736.875 0.479602316935816 -0.2171 -0.2711 1311 NINDS_000707 C[C@@]12CCC3C(CC[C@@H]4C[C@H](O)CC[C@@]43C)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D10 compound treatment 972490.0 -90100.0 -0.44 990560.0 -58800.0 -0.35 1010840.0 42716.875 0.244660577819003 -0.3147 -0.5133 1312 NINDS_000708 C[As](=O)(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D11 compound treatment 518630.0 -544000.0 -2.66 511300.0 -538000.0 -3.2 584750.0 -383373.125 -2.19576666792168 -4.6493 -0.9885 1313 NINDS_000709 Oc1ccc(Cl)cc1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D12 compound treatment 1045010.0 -17600.0 -0.09 1245970.0 197000.0 1.17 1279730.0 311606.875 1.78472601495016 1.656 0.7755 1314 NINDS_000710 CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3ccccc3C[C@H]2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D13 compound treatment 1241980.0 179000.0 0.88 1020420.0 -28900.0 -0.17 1044410.0 76286.875 0.436932498398024 0.6591 0.6629 1315 NINDS_000711 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D14 compound treatment 1028960.0 -33600.0 -0.16 1188430.0 139000.0 0.83 1212660.0 244536.875 1.4005830982616 1.1914 0.7287 1316 NINDS_000712 CC(C)(C)NCC(O)c1ccccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D15 compound treatment 1176160.0 114000.0 0.55 1159900.0 111000.0 0.66 1508700.0 540576.875 3.09614995462779 2.4876 0.7741 3046321 NINDS_000713 Nc1ncnc2n(cnc12)C3OC(CO)[C@H](O)C3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D16 compound treatment 919050.0 -144000.0 -0.7 906810.0 -143000.0 -0.85 984610.0 16486.875 0.0944284516114458 -0.8397 -0.7605 1317 NINDS_000714 Fc1ccc(cc1)C(c2ccccc2)(c3ccccc3F)n4ccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D17 compound treatment 649650.0 -413000.0 -2.02 611480.0 -438000.0 -2.6 668340.0 -299783.125 -1.71700557643523 -3.6594 -0.9852 1318 NINDS_000715 CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D18 compound treatment 924680.0 -138000.0 -0.67 1146440.0 97100.0 0.58 1265860.0 297736.875 1.70528569506839 0.929 0.4832 1319 NINDS_000716 NCCCCN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D19 compound treatment 1131050.0 68500.0 0.33 1105250.0 55900.0 0.33 990290.0 22166.875 0.12696060856375 0.4584 0.9385 445 NINDS_000717 NC(=O)c1cccc(N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D20 compound treatment 51360.0 -1010000.0 -4.94 53020.0 -996000.0 -5.92 71680.0 -896443.125 -5.13437120445662 -9.2374 -0.9968 2114344 NINDS_000718 CC1=C(O)C(=O)C=C2C1=CC=C3[C@@]2(C)CC[C@@]4(C)[C@@H]5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D21 compound treatment 949010.0 -114000.0 -0.55 997210.0 -52100.0 -0.31 1047870.0 79746.875 0.456749622175307 -0.2356 -0.301 1321 NINDS_000719 Cc1cc(=O)[nH]c(=S)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D22 compound treatment 916270.0 -146000.0 -0.71 943810.0 -106000.0 -0.63 1027800.0 59676.875 0.34179884928222 -0.5777 -0.5715 1322 NINDS_000720 COc1cc2ccc(=O)oc2cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D23 mock treatment 966290.0 -96300.0 -0.47 990080.0 -59200.0 -0.35 997460.0 29336.875 0.168026729223612 -0.378 -0.6184 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 D24 mock treatment 971970.0 -90600.0 -0.44 1045540.0 -3780.0 -0.02 1097440.0 129316.875 0.740661421493211 0.159 0.1842 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E01 mock treatment 1268190.0 206000.0 1.0 982880.0 -66400.0 -0.4 946310.0 -21813.125 -0.124934508119757 0.2797 0.2574 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E02 mock treatment 1108450.0 45900.0 0.22 1120110.0 70800.0 0.42 1056360.0 88236.875 0.505376032831128 0.6642 0.9559 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E03 compound treatment 1097770.0 35200.0 0.17 1062510.0 13200.0 0.08 921140.0 -46983.125 -0.269095492360864 -0.0109 -0.033 1323 NINDS_000721 CC1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E04 compound treatment 34760.0 -1030000.0 -5.02 31850.0 -1020000.0 -6.05 35480.0 -932643.125 -5.34170643010335 -9.4766 -0.9969 1324 NINDS_000722 CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E05 compound treatment 674940.0 -388000.0 -1.89 684830.0 -364000.0 -2.17 727790.0 -240333.125 -1.37650615199606 -3.1396 -0.984 1325 NINDS_000723 NC1(CCCC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E06 compound treatment 1096480.0 33900.0 0.17 1223400.0 174000.0 1.04 1035320.0 67196.875 0.384869592289495 0.9155 0.8197 1000132 NINDS_000724 CC1(C)C2CCC1(C)C(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E07 compound treatment 1049880.0 -12700.0 -0.06 1232070.0 183000.0 1.09 1218740.0 250616.875 1.43540625218237 1.4203 0.7884 1327 NINDS_000725 C[N+](C)(C)CCOC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E08 compound treatment 904540.0 -158000.0 -0.77 874030.0 -175000.0 -1.04 905980.0 -62143.125 -0.355924277465956 -1.2532 -0.9316 1328 NINDS_000726 OC(CCN1CCCCC1)(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E09 compound treatment 1049800.0 -12800.0 -0.06 997040.0 -52300.0 -0.31 1009370.0 41246.875 0.236241163959868 -0.0792 -0.2003 1329 NINDS_000727 NC(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E10 compound treatment 667210.0 -395000.0 -1.93 605920.0 -443000.0 -2.64 579790.0 -388333.125 -2.22417503033074 -3.9217 -0.9919 1330 NINDS_000728 ClCCN(CCCl)CCCl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E11 compound treatment 1043150.0 -19400.0 -0.1 1052930.0 3610.0 0.02 1159470.0 191346.875 1.09593777637902 0.5903 0.5365 1331 NINDS_000729 CC(=O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E12 compound treatment 1006850.0 -55700.0 -0.27 1102010.0 52700.0 0.31 1249930.0 281806.875 1.61404674079899 0.9555 0.5733 451 NINDS_000730 Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E13 compound treatment 1070690.0 8090.0 0.04 1119040.0 69700.0 0.41 1106190.0 138066.875 0.790776980178538 0.7188 0.8042 1332 NINDS_000731 NS(=O)(=O)c1cc(ccc1Cl)C2(O)NC(=O)c3ccccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E14 compound treatment 1603170.0 541000.0 2.64 1180600.0 131000.0 0.78 1235910.0 267786.875 1.53374729705404 2.8611 0.9076 1333 NINDS_000732 CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(Cc2ccccc2)NC(=O)C(CCN)NC1=O)C(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E15 compound treatment 1237990.0 175000.0 0.86 1047440.0 -1880.0 -0.01 1171110.0 202986.875 1.16260578816156 1.1595 0.8028 1334 NINDS_000733 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E16 compound treatment 1077400.0 14800.0 0.07 951620.0 -97700.0 -0.58 1010580.0 42456.875 0.243171429789496 -0.1533 -0.2418 1335 NINDS_000734 COc1cccc(C(=O)c2ccccc2O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E17 compound treatment 1092960.0 30400.0 0.15 1018280.0 -31000.0 -0.18 1129830.0 161706.875 0.926174901015239 0.5138 0.5375 1336 NINDS_000735 CC1(C)S[C@@H]2[C@H](NC(=O)C(C(=O)O)c3ccccc3)C(=O)N2[C@H]1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E18 compound treatment 968400.0 -94200.0 -0.46 1011800.0 -37500.0 -0.22 1044060.0 75936.875 0.434927876050611 -0.1434 -0.2136 1337 NINDS_000736 Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(=O)O)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E19 compound treatment 419440.0 -643000.0 -3.14 577310.0 -472000.0 -2.81 576690.0 -391433.125 -2.24193025683639 -4.7291 -0.9909 1338 NINDS_000737 CCCC(C(=O)OCCN(CC)CC)(c1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E20 compound treatment 978420.0 -84200.0 -0.41 1053610.0 4290.0 0.03 1040250.0 72126.875 0.413106129925914 0.0158 0.0271 1339 NINDS_000738 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E21 compound treatment 1053350.0 -9250.0 -0.05 1121600.0 72300.0 0.43 1102240.0 134116.875 0.768153385114877 0.6656 0.7551 1340 NINDS_000739 CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)C3=CCC=CC3)C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E22 compound treatment 1160650.0 98100.0 0.48 983810.0 -65500.0 -0.39 996320.0 28196.875 0.161497387863466 0.1449 0.2271 1341 NINDS_000740 CC(=O)OCC(COC(=O)C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E23 mock treatment 1206160.0 144000.0 0.7 1025490.0 -23800.0 -0.14 973230.0 5106.875 0.0292495878584148 0.34 0.4748 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 E24 mock treatment 1080590.0 18000.0 0.09 899110.0 -150000.0 -0.89 963450.0 -4673.125 -0.0267652880207279 -0.4804 -0.535 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F01 mock treatment 1114600.0 52000.0 0.25 1059420.0 10100.0 0.06 1025650.0 57526.875 0.329484740576683 0.3716 0.884 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F02 mock treatment 1075640.0 13000.0 0.06 1035360.0 -14000.0 -0.08 901120.0 -67003.125 -0.383759890632892 -0.2327 -0.585 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F03 compound treatment 32380.0 -1030000.0 -5.03 28330.0 -1020000.0 -6.07 27150.0 -940973.125 -5.38941644197178 -9.523 -0.9969 1342 NINDS_000741 CN(C)C(=S)SSC(=S)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F04 compound treatment 72590.0 -990000.0 -4.84 73520.0 -976000.0 -5.8 97860.0 -870263.125 -4.98442545287013 -9.0206 -0.9967 1343 NINDS_000742 COC1=CC(C)[C@@H]2C[C@H]3OC(=O)C[C@H]4C(=C(OC)C(=O)C([C@@]34C)[C@@]2(C)C1=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F05 compound treatment 1120660.0 58100.0 0.28 927710.0 -122000.0 -0.72 959850.0 -8273.125 -0.0473842607369767 -0.2811 -0.3612 1344 NINDS_000743 CCCC(=O)O[C@@]1(CCC2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F06 compound treatment 995900.0 -66700.0 -0.33 964800.0 -84500.0 -0.5 927170.0 -40953.125 -0.234558713061147 -0.6137 -0.9541 1000133 NINDS_000744 C[C@@]12CCC3C(CCC4=CC(=O)CC[C@]34C)C2CC[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F07 compound treatment 1281670.0 219000.0 1.07 959710.0 -89600.0 -0.53 929730.0 -38393.125 -0.219896332462925 0.1834 0.1508 1346 NINDS_000745 CCN(CC)CCNC(=O)COc1ccc(OC)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F08 compound treatment 358410.0 -704000.0 -3.44 324170.0 -725000.0 -4.31 345140.0 -622983.125 -3.56813112696068 -6.5361 -0.9949 1347 NINDS_000746 CC1=CCCC2(C)CCC3C(OC(=O)C3=C)C12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F09 compound treatment 848680.0 -214000.0 -1.05 779620.0 -270000.0 -1.6 863250.0 -104873.125 -0.600660028622987 -1.8762 -0.9351 1348 NINDS_000747 Clc1ccc(OCC(=O)N2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F10 compound treatment 879840.0 -183000.0 -0.89 806720.0 -243000.0 -1.44 793300.0 -174823.125 -1.00129812348454 -1.9265 -0.9779 3046390 NINDS_000748 CCC(=O)O[C@H]1CCC2C3CCC4=CC(=O)CC[C@]4(C)C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F11 compound treatment 1346360.0 284000.0 1.39 1170730.0 121000.0 0.72 1189960.0 221836.875 1.27056902030081 1.9509 0.9685 924 NINDS_000749 NC(=N)NC(=N)Nc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F12 compound treatment 992870.0 -69700.0 -0.34 1133600.0 84300.0 0.5 1151370.0 183246.875 1.04954508776746 0.6986 0.5765 3172708 NINDS_000750 CCC(C)C(=O)O[C@H]1[C@H](O)C2C(CN3CC(C)CCC3[C@@]2(C)O)C4C[C@]5(O[C@@]6(O)C7C(OC(=O)C)[C@@H](OC(=O)C)C5[C@@]41O)[C@@]7(C)CCC6OC(=O)C(C)(O)C(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F13 compound treatment 454750.0 -608000.0 -2.97 425410.0 -624000.0 -3.71 425490.0 -542633.125 -3.10792711091885 -5.651 -0.9952 1350 NINDS_000751 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F14 compound treatment 805760.0 -257000.0 -1.25 737070.0 -312000.0 -1.86 834770.0 -133353.125 -0.7637790127782 -2.2375 -0.945 1351 NINDS_000752 Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]3c(C)cc(N)c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F15 compound treatment 388660.0 -674000.0 -3.29 373510.0 -676000.0 -4.02 407950.0 -560173.125 -3.20838732798635 -6.0736 -0.9947 1352 NINDS_000753 COc1cc2CC[C@H](NC(=O)C)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F16 compound treatment 1070720.0 8120.0 0.04 1001510.0 -47800.0 -0.28 1137120.0 168996.875 0.967928320765643 0.4176 0.4136 1353 NINDS_000754 COC(=O)/C(=C/1\OC(=O)C(C1=O)c2ccccc2)/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F17 compound treatment 1071220.0 8620.0 0.04 1253440.0 204000.0 1.21 1240160.0 272036.875 1.55808913984405 1.6247 0.8224 1354 NINDS_000755 OS(=O)(=O)CCS 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F18 compound treatment 1330840.0 268000.0 1.31 910400.0 -139000.0 -0.83 1112090.0 143966.875 0.824569185463502 0.7558 0.4307 1355 NINDS_000756 CC(C)(O)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F19 compound treatment 228160.0 -834000.0 -4.08 196650.0 -853000.0 -5.07 196040.0 -772083.125 -4.42210024695865 -7.8343 -0.9959 1356 NINDS_000757 Oc1cccc2cccnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F20 compound treatment 972360.0 -90200.0 -0.44 881440.0 -168000.0 -1.0 870890.0 -97233.125 -0.55690198652517 -1.1524 -0.9406 1357 NINDS_000758 CCCCN1CCCCC1C(=O)Nc2c(C)cccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F21 compound treatment 306630.0 -756000.0 -3.69 262240.0 -787000.0 -4.68 297570.0 -670553.125 -3.84058794143622 -7.0521 -0.9943 1358 NINDS_000759 CN(CCCl)CCCl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F22 compound treatment 1028560.0 -34000.0 -0.17 1165140.0 116000.0 0.69 1004480.0 36356.875 0.208233726020297 0.4219 0.5712 1359 NINDS_000760 C[C@H]1C2C(CC3C4CC=C5CC(O)CCC5(C)C4CCC23C)O[C@@]61CCC(C)CN6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F23 mock treatment 1023890.0 -38700.0 -0.19 1019150.0 -30200.0 -0.18 1025460.0 57336.875 0.328396517016658 -0.0232 -0.0552 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 F24 mock treatment 935390.0 -127000.0 -0.62 1118630.0 69300.0 0.41 1069070.0 100946.875 0.578172461504328 0.2129 0.2257 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G01 mock treatment 1097980.0 35400.0 0.17 1060510.0 11200.0 0.07 999710.0 31586.875 0.180913587171267 0.2427 0.9373 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G02 mock treatment 1120080.0 57500.0 0.28 1110720.0 61400.0 0.37 971370.0 3246.875 0.0185964519550196 0.3837 0.8323 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G03 compound treatment 65440.0 -997000.0 -4.87 38660.0 -1010000.0 -6.01 50130.0 -917993.125 -5.25779866613306 -9.3182 -0.9962 1360 NINDS_000761 Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G04 compound treatment 32180.0 -1030000.0 -5.03 37640.0 -1010000.0 -6.02 37920.0 -930203.125 -5.32773134859567 -9.4559 -0.9972 1361 NINDS_000762 Clc1cc(Cl)c(OCC#CI)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G05 compound treatment 1028360.0 -34200.0 -0.17 1154210.0 105000.0 0.62 1050050.0 81926.875 0.46923555565348 0.5345 0.6695 1362 NINDS_000763 COc1c2occc2cc3ccc(=O)oc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G06 compound treatment 1064870.0 2270.0 0.01 1002610.0 -46700.0 -0.28 971690.0 3566.875 0.0204292495297972 -0.1422 -0.51 1363 NINDS_000764 CCOC(=O)CCC(=O)O[C@@H]1[C@H](C[C@@H](C)O[C@H]1O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G07 compound treatment 1073280.0 10700.0 0.05 1002100.0 -47200.0 -0.28 1009720.0 41596.875 0.238245786307281 0.0056 0.015 1364 NINDS_000765 OC(=O)/C(=C/c1cccc(O)c1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G08 compound treatment 579120.0 -483000.0 -2.36 505460.0 -544000.0 -3.23 551450.0 -416673.125 -2.38649216554698 -4.6088 -0.9886 1365 NINDS_000766 CN(C)CCC=C1c2ccccc2CCc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G09 compound treatment 1108640.0 46000.0 0.22 1109010.0 59700.0 0.35 999780.0 31656.875 0.18131451164075 0.4395 0.9603 3172713 NINDS_000767 CO/N=C(/C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(=O)O)COC(=O)C)\c3csc(N)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G10 compound treatment 1152120.0 89500.0 0.44 1241920.0 193000.0 1.15 1059650.0 91526.875 0.524219482896811 1.2164 0.9123 1367 NINDS_000768 Cc1cc(O)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G11 compound treatment 1043050.0 -19500.0 -0.1 1072050.0 22700.0 0.14 1076030.0 107906.875 0.618035808755743 0.3797 0.5935 1368 NINDS_000769 CCC(C)C(N)C1=NC(CS1)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NCCCCC2NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C(Cc3c[nH]cn3)NC(=O)C(Cc4ccccc4)NC(=O)C(NC(=O)C(CCCN)NC2=O)C(C)CC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G12 compound treatment 1123040.0 60400.0 0.3 1328250.0 279000.0 1.66 1167520.0 199396.875 1.14204409036952 1.7875 0.8782 3172714 NINDS_000770 C[n+]1ccccc1/C=N/O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G13 compound treatment 752530.0 -310000.0 -1.51 709020.0 -340000.0 -2.02 837120.0 -131003.125 -0.750319405588427 -2.4762 -0.9391 1370 NINDS_000771 C/C=C(/C(=C/C)/c1ccc(O)cc1)\c2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G14 compound treatment 1054470.0 -8130.0 -0.04 1083000.0 33700.0 0.2 1067890.0 99766.875 0.571414020447336 0.4226 0.6965 1371 NINDS_000772 CN(C)c1nc(nc(n1)N(C)C)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G15 compound treatment 1079040.0 16400.0 0.08 1095730.0 46400.0 0.28 1058010.0 89886.875 0.514826395326075 0.503 0.853 1372 NINDS_000773 OC(=O)c1cccnc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G16 compound treatment 1106750.0 44200.0 0.22 1087620.0 38300.0 0.23 1087310.0 119186.875 0.682641923266656 0.6502 0.8654 448 NINDS_000774 Clc1cccc(Cl)c1N=C2NCCN2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G17 compound treatment 287230.0 -775000.0 -3.79 292160.0 -757000.0 -4.5 253550.0 -714573.125 -4.09271215781657 -7.1496 -0.9975 1373 NINDS_000775 CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G18 compound treatment 691840.0 -371000.0 -1.81 578500.0 -471000.0 -2.8 584800.0 -383323.125 -2.19548029330062 -3.9298 -0.9843 1374 NINDS_000776 Oc1c(Br)cc(Br)c2cccnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G19 compound treatment 952960.0 -110000.0 -0.54 974960.0 -74400.0 -0.44 1011170.0 43046.875 0.246550650317993 -0.4222 -0.5728 1001324 NINDS_000777 OC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G20 compound treatment 865660.0 -197000.0 -0.96 985230.0 -64100.0 -0.38 930250.0 -37873.125 -0.216918036403912 -0.9008 -0.8519 3172716 NINDS_000778 NC(=O)N/N=C/c1ccc(o1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G21 compound treatment 1071380.0 8780.0 0.04 1139840.0 90500.0 0.54 1029200.0 61076.875 0.349817338671872 0.5375 0.8354 1377 NINDS_000779 CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G22 compound treatment 778350.0 -284000.0 -1.39 788190.0 -261000.0 -1.55 755780.0 -212343.125 -1.21619363912723 -2.4005 -0.9951 1378 NINDS_000780 NCCc1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G23 mock treatment 976880.0 -85700.0 -0.42 1097130.0 47800.0 0.28 1004560.0 36436.875 0.208691925413991 0.0428 0.0783 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 G24 mock treatment 1129640.0 67000.0 0.33 1133040.0 83700.0 0.5 1024250.0 56126.875 0.32146625118703 0.6622 0.9779 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H01 mock treatment 1151740.0 89100.0 0.44 1070080.0 20800.0 0.12 910950.0 -57173.125 -0.32745864013269 0.1337 0.2393 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H02 mock treatment 1200380.0 138000.0 0.67 1040800.0 -8520.0 -0.05 961500.0 -6623.125 -0.0379338982420293 0.3375 0.4992 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H03 compound treatment 1040250.0 -22300.0 -0.11 1052000.0 2680.0 0.02 971550.0 3426.875 0.019627400590832 -0.0425 -0.3792 1000134 NINDS_000781 Nc1ccn(C2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H04 compound treatment 694120.0 -368000.0 -1.8 739890.0 -309000.0 -1.84 701120.0 -267003.125 -1.52925837486894 -2.9847 -0.9968 1380 NINDS_000782 NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H05 compound treatment 1136840.0 74200.0 0.36 1201120.0 152000.0 0.9 1037800.0 69676.875 0.399073773494022 0.961 0.9139 1381 NINDS_000783 Nc1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H06 compound treatment 1157950.0 95400.0 0.47 1136180.0 86900.0 0.52 989980.0 21856.875 0.125185085913184 0.6395 0.9048 1382 NINDS_000784 OCCS 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H07 compound treatment 305600.0 -757000.0 -3.7 301070.0 -748000.0 -4.45 305040.0 -663083.125 -3.79780357305 -6.8969 -0.9965 1383 NINDS_000785 CC[C@H]([C@H]1CC[C@H](C)[C@@H](O1)[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@H]2OC3(O[C@@]4(CC[C@](C)(O4)[C@H]5CC[C@](O)(CC)[C@H](C)O5)[C@H](O)C=C3)[C@H](C)C[C@@H]2C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H08 compound treatment 1021560.0 -41000.0 -0.2 985690.0 -63600.0 -0.38 914340.0 -53783.125 -0.308042440824889 -0.5121 -0.9707 3045655 NINDS_000786 CC(=O)[C@@]1(O)CCC2C3C=C(Cl)C4=CC(=O)[C@@H]5CC5[C@]4(C)C3CC[C@@]21C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H09 compound treatment 1036130.0 -26500.0 -0.13 970460.0 -78900.0 -0.47 1051590.0 83466.875 0.478055893982098 -0.0694 -0.1017 1384 NINDS_000787 COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H10 compound treatment 1056050.0 -6550.0 -0.03 1029870.0 -19400.0 -0.12 1009610.0 41486.875 0.237615762140952 0.052 0.1952 1385 NINDS_000788 C(/C=C/N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H11 compound treatment 1052120.0 -10500.0 -0.05 1197090.0 148000.0 0.88 1093810.0 125686.875 0.719870624004327 0.8934 0.7857 1386 NINDS_000789 CN1CC(c2ccccc2)c3cccc(N)c3C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H12 compound treatment 52090.0 -1010000.0 -4.94 65830.0 -983000.0 -5.85 77000.0 -891123.125 -5.10390094477594 -9.1738 -0.9972 1387 NINDS_000790 OC(C1CCCCN1)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H13 compound treatment 1073470.0 10900.0 0.05 1071860.0 22500.0 0.13 1008500.0 40376.875 0.231258245553442 0.2416 0.8864 1388 NINDS_000791 Cc1cc(Nc2ccccc2C(=O)O)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H14 compound treatment 1093690.0 31100.0 0.15 1000220.0 -49100.0 -0.29 1020020.0 51896.875 0.297238958245438 0.0908 0.2046 1389 NINDS_000792 CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc4cccnc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H15 compound treatment 964720.0 -97900.0 -0.48 1184810.0 135000.0 0.81 1051520.0 83396.875 0.477654969512615 0.4649 0.442 3045662 NINDS_000793 CC(N)C(O)c1cccc(O)c1.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H16 compound treatment 1273980.0 211000.0 1.03 1188420.0 139000.0 0.83 1193440.0 225316.875 1.29050069392651 1.8189 0.9841 1390 NINDS_000794 CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H17 compound treatment 1283520.0 221000.0 1.08 1242740.0 193000.0 1.15 1148090.0 179966.875 1.03075891262599 1.8824 0.999 1391 NINDS_000795 CC(N)C(O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H18 compound treatment 1202910.0 140000.0 0.69 1102510.0 53200.0 0.32 1139360.0 171236.875 0.980757903789087 1.1447 0.9248 3172720 NINDS_000796 CNC(C)[C@@H]1CC[C@@H](N)[C@@H](OC2[C@@H](N)C[C@@H](N)[C@H](OC3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H19 compound treatment 607550.0 -455000.0 -2.22 517920.0 -531000.0 -3.16 540450.0 -427673.125 -2.44949458217997 -4.5222 -0.9885 1393 NINDS_000797 CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H20 compound treatment 787380.0 -275000.0 -1.34 760360.0 -289000.0 -1.72 775520.0 -192603.125 -1.10313293873313 -2.4053 -0.9838 360 NINDS_000798 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H21 compound treatment 999010.0 -63600.0 -0.31 894520.0 -155000.0 -0.92 929120.0 -39003.125 -0.223390102839845 -0.8398 -0.8424 1394 NINDS_000799 BrCCC(=O)N1CCN(CC1)C(=O)CCBr 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H22 compound treatment 891700.0 -171000.0 -0.83 904160.0 -145000.0 -0.86 882410.0 -85713.125 -0.490921273833174 -1.2639 -0.9741 1395 NINDS_000800 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H23 mock treatment 1078960.0 16400.0 0.08 1171160.0 122000.0 0.72 1008160.0 40036.875 0.22931089813024 0.5969 0.7811 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 H24 mock treatment 1004750.0 -57800.0 -0.28 1096830.0 47500.0 0.28 1032070.0 63946.875 0.36625524192066 0.2114 0.39 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I01 mock treatment 1138630.0 76000.0 0.37 1115840.0 66500.0 0.4 972500.0 4376.875 0.0250685183909532 0.4573 0.8419 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I02 mock treatment 1128760.0 66200.0 0.32 1041520.0 -7800.0 -0.05 970980.0 2856.875 0.0163627299107593 0.1693 0.5178 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I03 compound treatment 975250.0 -87300.0 -0.43 965220.0 -84100.0 -0.5 878940.0 -89183.125 -0.510795672534669 -0.83 -0.997 1396 NINDS_000801 Cc1cc(O)cc(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I04 compound treatment 1044800.0 -17800.0 -0.09 1099100.0 49800.0 0.3 1024640.0 56516.875 0.323699973231291 0.3076 0.6879 1397 NINDS_000802 CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I05 compound treatment 1056180.0 -6420.0 -0.03 1219690.0 170000.0 1.01 1061010.0 92886.875 0.532008872589616 0.874 0.7635 1398 NINDS_000803 CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OC(=O)C)c(C)c(C)c2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I06 compound treatment 1169320.0 107000.0 0.52 1228730.0 179000.0 1.07 983950.0 15826.875 0.0906483066134669 0.9694 0.8139 1000135 NINDS_000804 CC(C(=O)O)c1ccc(c(F)c1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I07 compound treatment 1116570.0 54000.0 0.26 1064080.0 14800.0 0.09 957810.0 -10313.125 -0.0590683452761844 0.1688 0.5942 1400 NINDS_000805 CC(C)[C@@H](C)/C=C/[C@@H](C)C1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)CCC3=C)\CCC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I08 compound treatment 936130.0 -126000.0 -0.62 818330.0 -231000.0 -1.37 741960.0 -226163.125 -1.29534758438794 -1.8976 -0.9552 2551 NINDS_000806 COc1cc(NC(C)CCCN)c2ncccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I09 compound treatment 866950.0 -196000.0 -0.96 833920.0 -215000.0 -1.28 830880.0 -137243.125 -0.786058958296591 -1.7452 -0.9799 3046406 NINDS_000807 Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I10 compound treatment 179560.0 -883000.0 -4.31 145290.0 -904000.0 -5.38 143250.0 -824873.125 -4.72445457187275 -8.3223 -0.9959 1401 NINDS_000808 CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I11 compound treatment 1166810.0 104000.0 0.51 1018400.0 -30900.0 -0.18 1029500.0 61376.875 0.351535586398226 0.3908 0.6054 1402 NINDS_000809 CC[N+](C)(C)c1cccc(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I12 compound treatment 1018020.0 -44600.0 -0.22 1149600.0 100000.0 0.6 1081870.0 113746.875 0.651484364495435 0.5947 0.6537 1403 NINDS_000810 COC(=O)C1=CCCN(C)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I13 compound treatment 720410.0 -342000.0 -1.67 775480.0 -274000.0 -1.63 765610.0 -202513.125 -1.15989238862703 -2.5751 -0.9881 1404 NINDS_000811 Nc1ccc(N=Nc2ccccc2)c(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I14 compound treatment 784070.0 -279000.0 -1.36 770030.0 -279000.0 -1.66 785400.0 -182723.125 -1.04654531361187 -2.3488 -0.9833 1000136 NINDS_000812 CC12CCC3C(=CCc4cc(O)ccc34)C2CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I15 compound treatment 902560.0 -160000.0 -0.78 995780.0 -53500.0 -0.32 915040.0 -53083.125 -0.304033196130063 -0.8108 -0.9036 1406 NINDS_000813 NC(=O)c1cc(cc(c1)[N+](=O)[O-])[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I16 compound treatment 1094430.0 31800.0 0.16 1242240.0 193000.0 1.15 1087040.0 118916.875 0.681095500312937 1.1454 0.8527 1407 NINDS_000814 NC(COCc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I17 compound treatment 826290.0 -236000.0 -1.15 940710.0 -109000.0 -0.65 957810.0 -10313.125 -0.0590683452761844 -1.0736 -0.8107 1408 NINDS_000815 NC1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I18 compound treatment 1024810.0 -37800.0 -0.18 1020540.0 -28800.0 -0.17 1101070.0 132946.875 0.761452218982096 0.2342 0.2921 1409 NINDS_000816 CCCC(C)(COC(=O)N)COC(=O)NC(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I19 compound treatment 798720.0 -264000.0 -1.29 876120.0 -173000.0 -1.03 868400.0 -99723.125 -0.571163442653909 -1.6687 -0.9557 1410 NINDS_000817 S=P(N1CC1)(N2CC2)N3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I20 compound treatment 1255940.0 193000.0 0.94 1076020.0 26700.0 0.16 1123620.0 155496.875 0.89060717307971 1.1513 0.8802 1411 NINDS_000818 COc1ccc(cc1)/C(=C(\c2ccc(OC)cc2)/c3cccc(OC)c3)/Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I21 compound treatment 1000610.0 -62000.0 -0.3 1179150.0 130000.0 0.77 1073830.0 105706.875 0.605435325429146 0.6204 0.6042 1412 NINDS_000819 CN(C)CCOC(c1ccc(Cl)cc1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I22 compound treatment 1274560.0 212000.0 1.04 1027530.0 -21800.0 -0.13 941620.0 -26503.125 -0.151796447575092 0.4355 0.4129 1413 NINDS_000820 CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I23 mock treatment 1132250.0 69700.0 0.34 1125450.0 76100.0 0.45 965080.0 -3043.125 -0.0174294753742041 0.4478 0.7903 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 I24 mock treatment 1171290.0 109000.0 0.53 1031440.0 -17900.0 -0.11 999940.0 31816.875 0.182230910428139 0.3504 0.6133 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J01 mock treatment 1234080.0 171000.0 0.84 1042880.0 -6440.0 -0.04 911420.0 -56703.125 -0.324766718694735 0.2741 0.3048 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J02 mock treatment 1136210.0 73600.0 0.36 1115520.0 66200.0 0.39 1093520.0 125396.875 0.718209651202185 0.8496 0.9498 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J03 compound treatment 1093710.0 31100.0 0.15 1109390.0 60100.0 0.36 976130.0 8006.875 0.0458593158798375 0.3205 0.8198 1414 NINDS_000821 CC(=O)NO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J04 compound treatment 1034630.0 -28000.0 -0.14 1295390.0 246000.0 1.46 911630.0 -56493.125 -0.323563945286288 0.5791 0.3848 142 NINDS_000822 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J05 compound treatment 901380.0 -161000.0 -0.79 1038000.0 -11300.0 -0.07 832320.0 -135803.125 -0.777811369210092 -0.9427 -0.85 1415 NINDS_000823 FC(F)(F)c1cccc(c1)N2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J06 compound treatment 1156100.0 93500.0 0.46 1203950.0 155000.0 0.92 1011520.0 43396.875 0.248555272665406 0.9382 0.888 1416 NINDS_000824 Cn1c(=O)n(C)c2[nH]c(nc2c1=O)C3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J07 compound treatment 393540.0 -669000.0 -3.27 366400.0 -683000.0 -4.06 366300.0 -601823.125 -3.4469373873285 -6.222 -0.9956 1417 NINDS_000825 CCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J08 compound treatment 406510.0 -656000.0 -3.21 400980.0 -648000.0 -3.86 428960.0 -539163.125 -3.08805271221735 -5.8595 -0.9951 383 NINDS_000826 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J09 compound treatment 1335680.0 273000.0 1.33 1193440.0 144000.0 0.86 1125440.0 157316.875 0.901031209286258 1.7853 0.9789 1418 NINDS_000827 CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N)C(=O)c4c(O)cccc4[C@@]3(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J10 compound treatment 1372730.0 310000.0 1.52 1406080.0 357000.0 2.12 1225760.0 257636.875 1.47561324897906 2.9516 0.9853 1419 NINDS_000828 NCCSSCCN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J11 compound treatment 1224840.0 162000.0 0.79 1235360.0 186000.0 1.11 1035600.0 67476.875 0.386473290167426 1.3195 0.9327 1420 NINDS_000829 COc1ccc2[C@@H](OC(=O)c2c1OC)[C@H]3N(C)CCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J12 compound treatment 1249030.0 186000.0 0.91 1214250.0 165000.0 0.98 1224290.0 256166.875 1.46719383511992 1.9392 0.9764 1421 NINDS_000830 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J13 compound treatment 1202770.0 140000.0 0.68 1238730.0 189000.0 1.13 1226310.0 258186.875 1.47876336981071 1.8995 0.9588 1422 NINDS_000831 CC1(C)O[C@@H]2C[C@H]3C4C[C@H](F)C5=CC(=O)C=CC5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J14 compound treatment 1136640.0 74000.0 0.36 1274130.0 225000.0 1.34 1133920.0 165796.875 0.949600345017866 1.529 0.9105 3172845 NINDS_000832 CCC(C)C(=O)O[C@H]1[C@H](O)C2C(CN3CC(C)CCC3[C@@]2(C)O)C4C[C@]5(O[C@@]6(O)C7C(OC(=O)C)[C@@H](OC(=O)C)C5[C@@]41O)[C@@]7(C)CCC6OC(=O)C(C)(O)CC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J15 compound treatment 1288380.0 226000.0 1.1 1259520.0 210000.0 1.25 1197290.0 229166.875 1.31255153974806 2.1164 0.9974 1424 NINDS_000833 CCCC(=O)Nc1ncnc2n(cnc12)C3O[C@@H]4COP(=O)(O)O[C@H]4[C@H]3OC(=O)CCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J16 compound treatment 1221870.0 159000.0 0.78 1231080.0 182000.0 1.08 1006020.0 37896.875 0.217054064348915 1.1986 0.8883 1425 NINDS_000834 CC(N)COc1c(C)cccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J17 compound treatment 971170.0 -91400.0 -0.45 1019480.0 -29800.0 -0.18 907200.0 -60923.125 -0.348936736712116 -0.5618 -0.9459 1426 NINDS_000835 ClCCNC(=O)N(CCCl)N=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J18 compound treatment 441440.0 -621000.0 -3.03 703680.0 -346000.0 -2.06 853940.0 -114183.125 -0.653982983064175 -3.3164 -0.8907 3172846 NINDS_000836 NC(CO)(CO)CO.OC(=O)C1CCn2c(ccc12)C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J19 compound treatment 1061350.0 -1250.0 -0.01 1216640.0 167000.0 0.99 1105950.0 137826.875 0.789402381997455 1.0267 0.8084 1428 NINDS_000837 CC(C)NCC(O)COc1cccc2[nH]ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J20 compound treatment 1053300.0 -9300.0 -0.05 1012160.0 -37200.0 -0.22 936670.0 -31453.125 -0.180147535059935 -0.2578 -0.893 1429 NINDS_000838 CCCCOC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J21 compound treatment 1160410.0 97800.0 0.48 1228050.0 179000.0 1.06 1166370.0 198246.875 1.13545747408516 1.5451 0.9496 1430 NINDS_000839 CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC21C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J22 compound treatment 715120.0 -347000.0 -1.7 848800.0 -201000.0 -1.19 817160.0 -150963.125 -0.864640154315184 -2.1678 -0.9645 1431 NINDS_000840 Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J23 mock treatment 1168100.0 106000.0 0.52 1324350.0 275000.0 1.64 998630.0 30506.875 0.174727895356393 1.3427 0.779 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 J24 mock treatment 1169360.0 107000.0 0.52 1105520.0 56200.0 0.33 1001990.0 33866.875 0.193972269891558 0.6061 0.9337 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K01 mock treatment 1090880.0 28300.0 0.14 1037530.0 -11800.0 -0.07 882000.0 -86123.125 -0.493269545725858 -0.2455 -0.4748 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K02 mock treatment 1292710.0 230000.0 1.12 1068990.0 19700.0 0.12 911210.0 -56913.125 -0.325969492103183 0.5285 0.4492 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K03 compound treatment 1049880.0 -12700.0 -0.06 1038910.0 -10400.0 -0.06 835330.0 -132793.125 -0.760571617022339 -0.5107 -0.6671 1432 NINDS_000841 CN(C)CCOC(C)(c1ccccc1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K04 compound treatment 1241870.0 179000.0 0.88 1312960.0 264000.0 1.57 880190.0 -87933.125 -0.503636307008194 1.1201 0.6005 1433 NINDS_000842 CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K05 compound treatment 59560.0 -1000000.0 -4.9 66990.0 -982000.0 -5.84 64850.0 -903273.125 -5.17348997769328 -9.1889 -0.9972 437 NINDS_000843 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K06 compound treatment 842740.0 -220000.0 -1.07 925250.0 -124000.0 -0.74 918810.0 -49313.125 -0.282440549702213 -1.2092 -0.9069 1434 NINDS_000844 CN1CCN2C(C1)c3ccccc3Cc4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K07 compound treatment 1005490.0 -57100.0 -0.28 1262240.0 213000.0 1.27 1046450.0 78326.875 0.448616582937231 0.8289 0.6042 1435 NINDS_000845 CN1[C@@H]2CC(O)C1CC(C2)OC(=O)[C@H](CO)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K08 compound treatment 544860.0 -518000.0 -2.53 536260.0 -513000.0 -3.05 521610.0 -446513.125 -2.557400539395 -4.6984 -0.9961 1436 NINDS_000846 CCCNC(C)C(=O)Nc1ccccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K09 compound treatment 1173250.0 111000.0 0.54 1206080.0 157000.0 0.93 969340.0 1216.875 0.0069696423400237 0.8544 0.7928 1437 NINDS_000847 CS(=O)(=O)OCCCCOS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K10 compound treatment 1327770.0 265000.0 1.3 1281440.0 232000.0 1.38 1091520.0 123396.875 0.706754666359825 1.953 0.9665 1438 NINDS_000848 CC(C(=O)O)c1cccc(Oc2ccccc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K11 compound treatment 1166520.0 104000.0 0.51 1293600.0 244000.0 1.45 1183750.0 215626.875 1.23500129236528 1.8449 0.935 1439 NINDS_000849 CSCCC(N)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K12 compound treatment 1129600.0 67000.0 0.33 1205010.0 156000.0 0.93 1021840.0 53716.875 0.307662994451986 0.9012 0.8757 1440 NINDS_000850 COc1ccc2cc(CCC(=O)C)ccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K13 compound treatment 1015580.0 -47000.0 -0.23 956400.0 -92900.0 -0.55 842470.0 -125653.125 -0.719677321135112 -0.8671 -0.9265 1441 NINDS_000851 CN1CCC(CC1)OC(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K14 compound treatment 1086720.0 24100.0 0.12 1111360.0 62000.0 0.37 1104340.0 136216.875 0.780181119199355 0.7315 0.8398 1442 NINDS_000852 CC(=O)NC1SCCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K15 compound treatment 880870.0 -182000.0 -0.89 1056090.0 6770.0 0.04 895040.0 -73083.125 -0.418583044553668 -0.731 -0.7441 1443 NINDS_000853 CN(C)CCOC(c1ccccc1)c2ccccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K16 compound treatment 1045250.0 -17300.0 -0.08 1243370.0 194000.0 1.15 940480.0 -27643.125 -0.158325788935238 0.5259 0.4503 1444 NINDS_000854 C1CN=C(N1)C2CCCc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K17 compound treatment 153030.0 -910000.0 -4.44 187260.0 -862000.0 -5.13 176880.0 -791243.125 -4.53183900174846 -8.1419 -0.9979 336 NINDS_000855 COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K18 compound treatment 968990.0 -93600.0 -0.46 986280.0 -63000.0 -0.37 893460.0 -74663.125 -0.427632482579132 -0.7274 -0.9967 1445 NINDS_000856 C/C=C(/C)\C(=O)O[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@H]4[C@@]2(C[C@@]5(O)[C@@H]6CN7C[C@@H](C)CC[C@H]7[C@@](C)(O)[C@@]6(O)[C@@H](O)C[C@@]45O)O[C@@]31O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K19 compound treatment 1113760.0 51200.0 0.25 1238630.0 189000.0 1.13 1075230.0 107106.875 0.613453814818798 1.1485 0.8792 1446 NINDS_000857 OC(COc1cccc2oc(cc(=O)c12)C(=O)O)COc3cccc4oc(cc(=O)c34)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K20 compound treatment 1309990.0 247000.0 1.21 1319130.0 270000.0 1.6 1092040.0 123916.875 0.709732962418838 2.034 0.9547 1447 NINDS_000858 NC(=O)c1ccccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K21 compound treatment 1133960.0 71400.0 0.35 1058500.0 9180.0 0.05 1068070.0 99946.875 0.572444969083148 0.5633 0.8377 3172849 NINDS_000859 CN1CCC[C@H]1c2cccnc2.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K22 compound treatment 1353220.0 291000.0 1.42 1379950.0 331000.0 1.97 936670.0 -31453.125 -0.180147535059935 1.8509 0.7611 1448 NINDS_000860 OC(=O)c1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K23 mock treatment 1106310.0 43700.0 0.21 986100.0 -63200.0 -0.38 971610.0 3486.875 0.0199710501361028 -0.0822 -0.1899 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 K24 mock treatment 1110800.0 48200.0 0.24 1186560.0 137000.0 0.82 1000390.0 32266.875 0.18480828201767 0.7139 0.8212 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L01 mock treatment 1176370.0 114000.0 0.56 1070520.0 21200.0 0.13 926510.0 -41613.125 -0.238338858059126 0.2561 0.4146 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L02 mock treatment 1037870.0 -24700.0 -0.12 1076880.0 27600.0 0.16 909730.0 -58393.125 -0.33444618088653 -0.1682 -0.4296 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L03 compound treatment 1149660.0 87100.0 0.43 1237680.0 188000.0 1.12 1002350.0 34226.875 0.196034167163183 1.0055 0.8282 1449 NINDS_000861 CN1[C@@H](CCC1=O)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L04 compound treatment 876600.0 -186000.0 -0.91 948370.0 -101000.0 -0.6 832520.0 -135603.125 -0.776665870725856 -1.3197 -0.9865 1450 NINDS_000862 NCCc1c[nH]c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L05 compound treatment 1045280.0 -17300.0 -0.08 1143420.0 94100.0 0.56 931370.0 -36753.125 -0.21050324489219 0.1527 0.2529 1451 NINDS_000863 CN(C)[C@H]1[C@@H]2C[C@@H]3[C@H](O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)[C@]2(O)C(=O)C(=C1O)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L06 compound treatment 1212960.0 150000.0 0.73 1193710.0 144000.0 0.86 929040.0 -39083.125 -0.22384830223354 0.7906 0.6863 1452 NINDS_000864 CCCCN(CCCC)CCCOC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L07 compound treatment 1244370.0 182000.0 0.89 1160330.0 111000.0 0.66 1040580.0 72456.875 0.414996202424903 1.1335 0.9591 3172851 NINDS_000865 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L08 compound treatment 1283700.0 221000.0 1.08 1293160.0 244000.0 1.45 1034170.0 66046.875 0.378282976005138 1.6793 0.909 1453 NINDS_000866 CN1CCCN=C1/C=C/c2sccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L09 compound treatment 1026650.0 -35900.0 -0.18 1181210.0 132000.0 0.78 926240.0 -41883.125 -0.239885281012844 0.2129 0.2539 1454 NINDS_000867 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@@H]2[C@@H](C)O[C@H](C[C@@H]2O)O[C@@H]3[C@@H](C)O[C@H](C[C@@H]3O)O[C@H]4CC[C@@]5(C)[C@H](CCC6C5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L10 compound treatment 1274560.0 212000.0 1.04 1123100.0 73800.0 0.44 1052540.0 84416.875 0.483497011782219 1.1304 0.9233 1455 NINDS_000868 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)C=CC4(C)C3[C@@H](O)C[C@@]21C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L11 compound treatment 1318940.0 256000.0 1.25 1270610.0 221000.0 1.32 1290240.0 322116.875 1.84492196029676 2.548 0.9841 1456 NINDS_000869 CC(C)[C@@H](C)/C=C/[C@@H](C)C1CC[C@H]2\C(=C\C=C\3/C[C@@H](O)CC[C@@H]3C)\CCC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L12 compound treatment 1144500.0 81900.0 0.4 1037610.0 -11700.0 -0.07 1099000.0 130876.875 0.749596309670253 0.6236 0.7315 1457 NINDS_000870 CC(=O)OCC(=O)[C@]12OC3(CCCC3)O[C@@H]2CC4C5CCC6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@@]41C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L13 compound treatment 1022720.0 -39900.0 -0.19 948080.0 -101000.0 -0.6 910930.0 -57193.125 -0.327573189981114 -0.6492 -0.9111 3172968 NINDS_000871 CCC1NC(=O)C(C(O)C(C)C/C=C/C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L14 compound treatment 1253760.0 191000.0 0.93 1213540.0 164000.0 0.98 1113280.0 145156.875 0.831384901444706 1.5831 0.9978 3045683 NINDS_000872 C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1.OC(C(O)C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L15 compound treatment 1211080.0 148000.0 0.73 1219170.0 170000.0 1.01 983150.0 15026.875 0.0860663126765227 1.0517 0.8437 1458 NINDS_000873 NC(Cc1ccc(Cl)cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L16 compound treatment 687280.0 -375000.0 -1.83 646730.0 -403000.0 -2.39 645050.0 -323073.125 -1.85039887492451 -3.5092 -0.9918 1459 NINDS_000874 OC1CCN(CCCN2c3ccccc3Sc4ccc(C#N)cc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L17 compound treatment 538950.0 -524000.0 -2.56 576330.0 -473000.0 -2.81 583840.0 -384283.125 -2.20097868602496 -4.3717 -0.9951 3172969 NINDS_000875 CC(CNC(=O)CCC/1(C)C(CC(=O)N)C2N([Co]C[C@H]3OC([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)\C1=C(\C)/C/6=N/C(=C\C\7=N/C(=C(/C)\C8=NC2(C)C(C)(CC(=O)N)C8CCC(=O)N)/C(C)(CC(=O)N)C7CCC(=O)N)/C(C)(C)C6CCC(=O)C)OP(=O)(O)O[C@H]9[C@@H](O)C(O[C@@H]9CO)n%10cnc%11cc(C)c(C)cc%10%11 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L18 compound treatment 1174280.0 112000.0 0.55 1268920.0 220000.0 1.31 963640.0 -4483.125 -0.0256770644607036 1.0542 0.7447 1461 NINDS_000876 CN1CCCN=C1COC(=O)C(O)(C2CCCCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L19 compound treatment 1305990.0 243000.0 1.19 1257920.0 209000.0 1.24 1039590.0 71466.875 0.409325984927935 1.6391 0.9279 1462 NINDS_000877 CC1C(CCC(C)(C)N1C)OC(=O)C(O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L20 compound treatment 1169140.0 107000.0 0.52 1025680.0 -23600.0 -0.14 845450.0 -122673.125 -0.702609393719995 -0.1863 -0.2103 1463 NINDS_000878 COc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L21 compound treatment 1242920.0 180000.0 0.88 1154440.0 105000.0 0.63 1026320.0 58196.875 0.333322160498873 1.062 0.9394 1464 NINDS_000879 CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2C3CCC4=CC(=O)CCC4(C)[C@@]3(F)[C@@H](O)CC21C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L22 compound treatment 229140.0 -833000.0 -4.07 223130.0 -826000.0 -4.91 240990.0 -727133.125 -4.1646494626266 -7.592 -0.9963 1465 NINDS_000880 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L23 mock treatment 1096480.0 33900.0 0.17 1044650.0 -4670.0 -0.03 926560.0 -41563.125 -0.238052483438067 -0.0579 -0.1987 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 L24 mock treatment 954570.0 -108000.0 -0.53 1233970.0 185000.0 1.1 959150.0 -8973.125 -0.0513935054318029 0.2996 0.2457 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M01 mock treatment 1096260.0 33700.0 0.16 1131890.0 82600.0 0.49 1104230.0 136106.875 0.779551095033025 0.8285 0.8853 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M02 mock treatment 972900.0 -89700.0 -0.44 1144960.0 95600.0 0.57 955060.0 -13063.125 -0.07481894943443 0.0321 0.0445 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M03 compound treatment 1344440.0 282000.0 1.38 1064160.0 14800.0 0.09 912220.0 -55903.125 -0.320184724757791 0.6611 0.4667 1466 NINDS_000881 NCCCCC(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCCN)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M04 compound treatment 948500.0 -114000.0 -0.56 877050.0 -172000.0 -1.02 756980.0 -211143.125 -1.20932064822181 -1.6115 -0.9592 1467 NINDS_000882 CCCCOc1ccc(OCCCN2CCOCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M05 compound treatment 276880.0 -786000.0 -3.84 482430.0 -567000.0 -3.37 231300.0 -736823.125 -4.22014886418784 -6.5991 -0.9959 1468 NINDS_000883 CCCCC(=O)O[C@H]1CCC2C3CCc4cc(O)ccc4C3CC[C@]12C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M06 compound treatment 1305390.0 243000.0 1.19 1229120.0 180000.0 1.07 969610.0 1486.875 0.00851606529374236 1.3071 0.8185 1469 NINDS_000884 CCC1(CCC(=O)NC1=O)c2ccc(N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M07 compound treatment 1143750.0 81200.0 0.4 1493030.0 444000.0 2.64 935090.0 -33033.125 -0.189196973085399 1.6431 0.6143 1470 NINDS_000885 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M08 compound treatment 1267070.0 204000.0 1.0 1374690.0 325000.0 1.93 1001480.0 33356.875 0.191051248756756 1.8042 0.8254 1471 NINDS_000886 CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M09 compound treatment 1393130.0 331000.0 1.61 1300930.0 252000.0 1.5 968060.0 -63.125 -3.61547959087002E-4 1.796 0.8158 1000138 NINDS_000887 CC(C)Cc1ccc(cc1)C(C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M10 compound treatment 1279490.0 217000.0 1.06 882010.0 -167000.0 -0.99 860130.0 -107993.125 -0.618529804977069 -0.3197 -0.2024 1473 NINDS_000888 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M11 compound treatment 1258560.0 196000.0 0.96 1251290.0 202000.0 1.2 1205940.0 237816.875 1.36209434919127 2.0326 0.9901 3172973 NINDS_000889 COC(=O)[C@@]1(O)OC[C@]2(C3[C@H]4OC[C@@]3([C@@H](C[C@@H]2OC(=O)/C(=C/C)/C)OC(=O)C)C(=O)OC)[C@@H]1[C@@](C)([C@@H]4O)C56O[C@@]6(C)[C@H]7C[C@@H]5OC8OC=C[C@]78O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M12 compound treatment 1051310.0 -11300.0 -0.06 1133230.0 83900.0 0.5 913030.0 -55093.125 -0.315545455896635 0.0741 0.1249 1475 NINDS_000890 Cl[Pt]Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M13 compound treatment 217940.0 -845000.0 -4.13 141670.0 -908000.0 -5.4 194670.0 -773453.125 -4.42994691157567 -8.0564 -0.9933 1476 NINDS_000891 CNCCCC1(CCC2c3ccccc31)c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M14 compound treatment 1107290.0 44700.0 0.22 1013770.0 -35500.0 -0.21 892110.0 -76013.125 -0.435364597347726 -0.2473 -0.4658 1477 NINDS_000892 O=C1O[Pt]OC(=O)C21CCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M15 compound treatment 470480.0 -592000.0 -2.89 605280.0 -444000.0 -2.64 643800.0 -324323.125 -1.85755824045099 -4.2672 -0.9844 1478 NINDS_000893 Cc1ccc(cc1)c2cc(nn2c3ccc(cc3)S(=O)(=O)N)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M16 compound treatment 1012160.0 -50400.0 -0.25 1032240.0 -17100.0 -0.1 796960.0 -171163.125 -0.980335501223025 -0.7669 -0.7549 1479 NINDS_000894 CC(C)NCC(O)c1ccc(O)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M17 compound treatment 1181460.0 119000.0 0.58 1205970.0 157000.0 0.93 954120.0 -14003.125 -0.0802027923103394 0.8268 0.7512 1480 NINDS_000895 Clc1ccc2oc(=O)[nH]c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M18 compound treatment 1078100.0 15500.0 0.08 1188000.0 139000.0 0.82 990880.0 22756.875 0.130339829092246 0.5951 0.7099 1481 NINDS_000896 Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M19 compound treatment 1247040.0 184000.0 0.9 1237350.0 188000.0 1.12 1108360.0 140236.875 0.8032056387325 1.6296 0.9904 1482 NINDS_000897 CN1CCc2cc3OCOc3cc2C1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M20 compound treatment 957210.0 -105000.0 -0.51 1058010.0 8690.0 0.05 858270.0 -109853.125 -0.629182940880465 -0.6307 -0.7742 3000787 NINDS_000898 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M21 compound treatment 1352040.0 289000.0 1.41 1256820.0 208000.0 1.23 1013170.0 45046.875 0.258005635160353 1.6778 0.8857 1484 NINDS_000899 CCC(C)C(N)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M22 compound treatment 1112910.0 50300.0 0.25 1184070.0 135000.0 0.8 967410.0 -713.125 -0.00408441803285415 0.6022 0.7185 1485 NINDS_000900 CCC(=C)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M23 mock treatment 1041410.0 -21200.0 -0.1 1005930.0 -43400.0 -0.26 944160.0 -23963.125 -0.137248616825295 -0.288 -0.9288 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 M24 mock treatment 905620.0 -157000.0 -0.77 1081530.0 32200.0 0.19 916260.0 -51863.125 -0.297045655376223 -0.5037 -0.5965 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N01 mock treatment 1088920.0 26300.0 0.13 1053830.0 4510.0 0.03 941160.0 -26963.125 -0.154431094088835 6.0E-4 0.0029 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N02 mock treatment 1204870.0 142000.0 0.7 1281840.0 233000.0 1.38 905840.0 -62283.125 -0.356726126404921 0.9937 0.6257 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N03 compound treatment 1288160.0 226000.0 1.1 1407040.0 358000.0 2.13 961060.0 -7063.125 -0.0404539949073486 1.8411 0.7684 1486 NINDS_000901 CC(C)NCC(O)COc1ccc(NC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N04 compound treatment 1428110.0 366000.0 1.79 1228500.0 179000.0 1.07 1027160.0 59036.875 0.338133254132665 1.8415 0.874 1487 NINDS_000902 CCC(Cc1c(I)cc(I)c(N)c1I)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N05 compound treatment 1090500.0 27900.0 0.14 1119680.0 70400.0 0.42 844190.0 -123933.125 -0.709826034170682 -0.0895 -0.1072 104 NINDS_000903 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N06 compound treatment 1284640.0 222000.0 1.08 1208010.0 159000.0 0.94 916770.0 -51353.125 -0.294124634241421 1.0014 0.6823 1488 NINDS_000904 NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C3CC4CC3C=C4)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N07 compound treatment 1400530.0 338000.0 1.65 1324750.0 275000.0 1.64 1077850.0 109726.875 0.628459844962291 2.2617 0.9388 3172974 NINDS_000905 C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)C4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)C4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N08 compound treatment 963200.0 -99400.0 -0.49 953410.0 -95900.0 -0.57 738840.0 -229283.125 -1.31321736074202 -1.3678 -0.9048 1489 NINDS_000906 CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N09 compound treatment 1188860.0 126000.0 0.62 1294880.0 246000.0 1.46 921830.0 -46293.125 -0.265143522590249 1.0462 0.6509 1490 NINDS_000907 NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)C(O)C1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N10 compound treatment 1188000.0 125000.0 0.61 1190090.0 141000.0 0.84 1042880.0 74756.875 0.428169434993618 1.0843 0.9661 3045773 NINDS_000908 CCC(=O)O[C@@H](OP(=O)(CCCCc1ccccc1)CC(=O)N2C[C@@H](C[C@H]2C(=O)O)C3CCCCC3)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N11 compound treatment 1171010.0 108000.0 0.53 1159940.0 111000.0 0.66 861840.0 -106283.125 -0.608735792936851 0.3342 0.321 1000139 NINDS_000909 CO[C@]1(NC(=O)C(C(=O)O)c2ccc(O)cc2)[C@H]3OCC(=C(N3C1=O)C(=O)O)CSc4nnnn4C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N12 compound treatment 1037950.0 -24600.0 -0.12 1034760.0 -14600.0 -0.09 1022690.0 54566.875 0.312531363009989 0.0609 0.1761 1493 NINDS_000910 CCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N13 compound treatment 1040280.0 -22300.0 -0.11 1024250.0 -25100.0 -0.15 1022200.0 54076.875 0.309724891723611 0.0298 0.0827 1494 NINDS_000911 C1CN(CCN1)c2ccc3ccccc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N14 compound treatment 1035850.0 -26700.0 -0.13 1058600.0 9280.0 0.06 1158080.0 189956.875 1.08797656191358 0.5846 0.5328 1495 NINDS_000912 OC(=O)CCCCC1CCSS1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N15 compound treatment 154880.0 -908000.0 -4.43 167430.0 -882000.0 -5.24 186240.0 -781883.125 -4.47822967268622 -8.1738 -0.9969 1496 NINDS_000913 CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N16 compound treatment 1371680.0 309000.0 1.51 1259470.0 210000.0 1.25 1084570.0 116446.875 0.666948594032622 1.9784 0.9555 1497 NINDS_000914 NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)C2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@H](N)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N17 compound treatment 1133680.0 71100.0 0.35 1113240.0 63900.0 0.38 1061140.0 93016.875 0.532753446604369 0.7276 0.982 1498 NINDS_000915 OC(=O)P(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N18 compound treatment 972210.0 -90400.0 -0.44 907930.0 -141000.0 -0.84 917190.0 -50933.125 -0.291719087424525 -0.9088 -0.9148 1499 NINDS_000916 Cc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N19 compound treatment 1024370.0 -38200.0 -0.19 987400.0 -61900.0 -0.37 864090.0 -104033.125 -0.595848934989196 -0.6644 -0.9166 1500 NINDS_000917 C[C@@H]1OC(Oc2c(oc3cc(O)cc(O)c3c2=O)c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N20 compound treatment 1077980.0 15400.0 0.08 1061760.0 12400.0 0.07 938510.0 -29613.125 -0.169608949004963 -0.0118 -0.0591 1501 NINDS_000918 NCCc1ccc(O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N21 compound treatment 1137410.0 74800.0 0.37 1183630.0 134000.0 0.8 1010440.0 42316.875 0.242369580850531 0.8121 0.8912 1502 NINDS_000919 OC(=O)c1c2ccccc2cc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N22 compound treatment 1075360.0 12800.0 0.06 1132520.0 83200.0 0.49 907150.0 -60973.125 -0.349223111333175 0.12 0.1972 1503 NINDS_000920 Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N23 mock treatment 1281970.0 219000.0 1.07 1277520.0 228000.0 1.36 1053020.0 84896.875 0.486246208144386 1.683 0.9369 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 N24 mock treatment 974240.0 -88400.0 -0.43 1190160.0 141000.0 0.84 977340.0 9216.875 0.0527895817094656 0.2648 0.2806 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O01 mock treatment 1114880.0 52300.0 0.26 1073120.0 23800.0 0.14 857540.0 -110583.125 -0.633364010347926 -0.1365 -0.1957 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O02 mock treatment 1241530.0 179000.0 0.87 1335090.0 286000.0 1.7 1179040.0 210916.875 1.20802480306152 2.1833 0.9657 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O03 compound treatment 859840.0 -203000.0 -0.99 925470.0 -124000.0 -0.74 705690.0 -262433.125 -1.50308373450414 -1.8649 -0.9588 1504 NINDS_000921 O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)c4ncccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O04 compound treatment 1212160.0 150000.0 0.73 1070260.0 20900.0 0.12 877560.0 -90563.125 -0.518699612075898 0.1943 0.2148 1505 NINDS_000922 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O05 compound treatment 1214910.0 152000.0 0.74 1135840.0 86500.0 0.51 956960.0 -11163.125 -0.0639367138341876 0.6898 0.7605 1506 NINDS_000923 OCc1cc(=O)c(O)co1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O06 compound treatment 1201830.0 139000.0 0.68 1224610.0 175000.0 1.04 998100.0 29976.875 0.171692324373167 1.0937 0.8704 1507 NINDS_000924 CC(N)CCCC(C)(C)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O07 compound treatment 1213760.0 151000.0 0.74 1214590.0 165000.0 0.98 1037680.0 69556.875 0.398386474403481 1.2238 0.947 1508 NINDS_000925 CSCCC(NC=O)C(=O)NC(C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O08 compound treatment 1063640.0 1040.0 0.01 1117160.0 67800.0 0.4 848340.0 -119783.125 -0.686056940622784 -0.1602 -0.2013 142 NINDS_000926 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O09 compound treatment 1221520.0 159000.0 0.78 1162890.0 114000.0 0.68 991580.0 23456.875 0.134349073787072 0.9158 0.8824 1509 NINDS_000927 Cn1c(COC(=O)N)ncc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O10 compound treatment 1075710.0 13100.0 0.06 1234080.0 185000.0 1.1 956430.0 -11693.125 -0.0669722848174131 0.6327 0.5738 1510 NINDS_000928 CN(C)CCN(Cc1cccs1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O11 compound treatment 1194110.0 132000.0 0.64 1175010.0 126000.0 0.75 950350.0 -17773.125 -0.101795438738189 0.7437 0.7506 1511 NINDS_000929 Oc1ccc(cc1)C2(OC(=O)c3ccccc32)c4ccc(O)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O12 compound treatment 1102720.0 40100.0 0.2 1021330.0 -28000.0 -0.17 1068360.0 100236.875 0.57410594188529 0.3486 0.5541 1512 NINDS_000930 CC(C)NCC(O)c1ccc2ccccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O13 compound treatment 1152860.0 90300.0 0.44 1131520.0 82200.0 0.49 989990.0 21866.875 0.125242360837395 0.6091 0.9089 2431 NINDS_000931 CCN(CC)CCNC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O14 compound treatment 1119840.0 57200.0 0.28 1020200.0 -29100.0 -0.17 961870.0 -6253.125 -0.0358147260461926 0.0408 0.1234 1513 NINDS_000932 CCOC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O15 compound treatment 1143840.0 81200.0 0.4 1221040.0 172000.0 1.02 1053490.0 85366.875 0.48893812958234 1.101 0.9177 1514 NINDS_000933 CC1OC1P(=O)(O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O16 compound treatment 1156240.0 93600.0 0.46 1243130.0 194000.0 1.15 1075860.0 107736.875 0.617062135044142 1.2858 0.9283 3173095 NINDS_000934 CC(Oc1ccccc1)C(=O)NC2[C@H]3SC(C)(C)C(N3C2=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O17 compound treatment 1066500.0 3900.0 0.02 1121770.0 72500.0 0.43 985920.0 17796.875 0.101931466683192 0.3186 0.719 1515 NINDS_000935 CC[C@@H]1[C@@H](Cc2cccn2C)COC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O18 compound treatment 1089200.0 26600.0 0.13 1084680.0 35400.0 0.21 915740.0 -52383.125 -0.300023951435237 0.0232 0.0598 1516 NINDS_000936 Nc1c2CCCCc2nc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O19 compound treatment 1255600.0 193000.0 0.94 1123240.0 73900.0 0.44 1010670.0 42546.875 0.243686904107403 0.9389 0.8787 1517 NINDS_000937 CCC1(NC(=O)N(C)C1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O20 compound treatment 1074930.0 12300.0 0.06 1154580.0 105000.0 0.63 1059440.0 91316.875 0.523016709488363 0.6981 0.8536 1518 NINDS_000938 OC(=O)c1cc(ccc1O)c2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O21 compound treatment 1139390.0 76800.0 0.38 1152320.0 103000.0 0.61 965120.0 -3003.125 -0.0172003756773569 0.5603 0.7799 1519 NINDS_000939 CC1(C)OC(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O22 compound treatment 188160.0 -874000.0 -4.27 598610.0 -451000.0 -2.68 565160.0 -402963.125 -2.3079682444526 -5.3465 -0.964 1520 NINDS_000940 CC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O23 mock treatment 1220530.0 158000.0 0.77 1166360.0 117000.0 0.7 937470.0 -30653.125 -0.17556554112299 0.746 0.7078 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 O24 mock treatment 994180.0 -68400.0 -0.33 912880.0 -136000.0 -0.81 840230.0 -127893.125 -0.732506904158556 -1.0843 -0.9486 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P01 mock treatment 966720.0 -95900.0 -0.47 963540.0 -85800.0 -0.51 876380.0 -91743.125 -0.525458053132891 -0.8683 -0.9988 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P02 mock treatment 1114080.0 51500.0 0.25 1257020.0 208000.0 1.24 1016220.0 48096.875 0.275474487044953 1.0174 0.7885 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P03 compound treatment 513280.0 -549000.0 -2.68 590240.0 -459000.0 -2.73 562190.0 -405933.125 -2.32497889694351 -4.468 -0.9975 1000140 NINDS_000941 CC[C@@H]1OC(OC(C(NC(=O)c2nc(nc(N)c2C)C(CC(=O)N)NCC(N)C(=O)N)C(=O)NC(C)C(O)C(C)C(=O)NC(C(C)O)C(=O)NCCc3nc(cs3)c4nc(cs4)C(=O)NCCCCNC(=N)N)c5c[nH]cn5)[C@@H](O[C@H]6O[C@H](CO)[C@@H](O)[C@H](OC(=O)N)[C@@H]6O)[C@@H](C)[C@@H]1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P04 compound treatment 699460.0 -363000.0 -1.77 636970.0 -412000.0 -2.45 494280.0 -473843.125 -2.71393290726586 -4.0069 -0.9857 1522 NINDS_000942 CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P05 compound treatment 1084710.0 22100.0 0.11 1175520.0 126000.0 0.75 1110720.0 142596.875 0.816722520846485 0.9672 0.8679 1523 NINDS_000943 CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P06 compound treatment 1298590.0 236000.0 1.15 1160960.0 112000.0 0.66 1022280.0 54156.875 0.310183091117305 1.2281 0.8989 1524 NINDS_000944 CC(C)Nc1c(C)n(C)n(c2ccccc2)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P07 compound treatment 1207150.0 145000.0 0.71 1162140.0 113000.0 0.67 914450.0 -53673.125 -0.307412416658559 0.6176 0.6046 1525 NINDS_000945 CC(CNC(=O)c1ccccc1)C(=O)OCC(=O)[C@]23OC(C)(C)O[C@@H]3CC4C5CCC6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@@]42C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P08 compound treatment 914560.0 -148000.0 -0.72 884410.0 -165000.0 -0.98 805200.0 -162923.125 -0.9331409636725 -1.5225 -0.992 1526 NINDS_000946 CC1CCCC(C)N1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P09 compound treatment 400000.0 -663000.0 -3.24 352990.0 -696000.0 -4.14 345330.0 -622793.125 -3.56704290340065 -6.3192 -0.9948 1527 NINDS_000947 COc1cc2OC[C@H]3Oc4c5C[C@@H](Oc5ccc4C(=O)[C@H]3c2cc1OC)C(=C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P10 compound treatment 1187090.0 124000.0 0.61 1150820.0 102000.0 0.6 910290.0 -57833.125 -0.331238785130669 0.5084 0.5534 1528 NINDS_000948 NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P11 compound treatment 1033330.0 -29300.0 -0.14 1021660.0 -27700.0 -0.16 901540.0 -66583.125 -0.381354343815996 -0.3977 -0.9054 1529 NINDS_000949 COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P12 compound treatment 840590.0 -222000.0 -1.08 859200.0 -190000.0 -1.13 754080.0 -214043.125 -1.22593037624323 -1.9868 -0.9987 1530 NINDS_000950 COc1ccc2c3CCN=C(C)c3[nH]c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P13 compound treatment 49510.0 -1010000.0 -4.95 33460.0 -1020000.0 -6.04 111960.0 -856163.125 -4.90366780973148 -9.1766 -0.9951 1531 NINDS_000951 O=c1n([se]c2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P14 compound treatment 938320.0 -124000.0 -0.61 1046680.0 -2640.0 -0.02 859200.0 -108923.125 -0.623856372928767 -0.7198 -0.8267 1532 NINDS_000952 OC[C@H]1O[C@H](Oc2cc3ccc(=O)oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P15 compound treatment 1268430.0 206000.0 1.01 1105830.0 56500.0 0.34 1007410.0 39286.875 0.225015278814355 0.9046 0.8345 1533 NINDS_000953 Cc1cc(CC(=O)O)n(C)c1C(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P16 compound treatment 976190.0 -86400.0 -0.42 999520.0 -49800.0 -0.3 962240.0 -5883.125 -0.033695553850356 -0.4342 -0.8401 1534 NINDS_000954 O=C(/C=C/C=C/c1ccc2OCOc2c1)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P17 compound treatment 1057880.0 -4720.0 -0.02 1101660.0 52300.0 0.31 993850.0 25726.875 0.147350481583151 0.2515 0.7286 1535 NINDS_000955 COc1ccc(OC)c(c1)C(O)CNC(=O)CN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P18 compound treatment 1059040.0 -3560.0 -0.02 1079650.0 30300.0 0.18 947870.0 -20253.125 -0.115999619942716 0.0271 0.1261 1000141 NINDS_000956 OC[C@H]1O[C@@H](Oc2cc3ccc(=O)oc3cc2O)[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P19 compound treatment 1050080.0 -12500.0 -0.06 1138120.0 88800.0 0.53 964090.0 -4033.125 -0.0230996928711725 0.2562 0.4816 1537 NINDS_000957 NC(Cc1ccc(F)cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P20 compound treatment 944370.0 -118000.0 -0.58 985540.0 -63800.0 -0.38 889170.0 -78953.125 -0.452203425065996 -0.8135 -0.9851 1538 NINDS_000958 Oc1ccc(c(O)c1)c2oc3cc(O)cc(O)c3c(=O)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P21 compound treatment 1153280.0 90700.0 0.44 1155690.0 106000.0 0.63 867300.0 -100823.125 -0.577463684317207 0.2876 0.2983 1539 NINDS_000959 C[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@H]23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P22 compound treatment 937470.0 -125000.0 -0.61 963810.0 -85500.0 -0.51 960400.0 -7723.125 -0.0442341399053276 -0.6721 -0.8439 1000142 NINDS_000960 CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]3(C)C2C(=O)C=C4[C@H]5C[C@](C)(CC[C@]5(C)CC[C@]43C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P23 mock treatment 1121280.0 58700.0 0.29 930080.0 -119000.0 -0.71 1053060.0 84936.875 0.486475307841233 0.037 0.0409 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.502 P24 mock treatment 980250.0 -82300.0 -0.4 925020.0 -124000.0 -0.74 935360.0 -32763.125 -0.187650550131681 -0.7674 -0.89 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A01 mock treatment 879200.0 -292000.0 -1.43 764020.0 -234000.0 -1.39 739900.0 -288791.13793103 -1.65404905380399 -2.5839 -0.997 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A02 mock treatment 1000800.0 -171000.0 -0.83 814050.0 -184000.0 -1.1 794880.0 -233811.13793103 -1.3391515204875 -1.8873 -0.9826 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A03 compound treatment 954190.0 -217000.0 -1.06 843520.0 -155000.0 -0.92 772960.0 -255731.13793103 -1.46469815435977 -1.9901 -0.9804 1541 NINDS_000961 CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)OC(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A04 mock treatment 917780.0 -254000.0 -1.24 825930.0 -172000.0 -1.02 842150.0 -186541.13793103 -1.06841295373831 -1.9244 -0.9965 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A05 compound treatment 899680.0 -272000.0 -1.33 886790.0 -111000.0 -0.66 848450.0 -180241.13793103 -1.03232975148488 -1.7457 -0.9654 1542 NINDS_000962 CNC(C)Cc1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A06 mock treatment 1063870.0 -108000.0 -0.53 856270.0 -142000.0 -0.84 894260.0 -134431.13793103 -0.769953323670609 -1.2358 -0.9824 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A07 compound treatment 848770.0 -323000.0 -1.58 767870.0 -230000.0 -1.37 731070.0 -297621.13793103 -1.70462281188301 -2.6857 -0.9961 1543 NINDS_000963 CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A08 mock treatment 987220.0 -184000.0 -0.9 879470.0 -119000.0 -0.71 897790.0 -130901.13793103 -0.749735275423843 -1.3607 -0.9944 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A09 compound treatment 949030.0 -223000.0 -1.09 926240.0 -72000.0 -0.43 859880.0 -168811.13793103 -0.966864513110785 -1.4332 -0.9449 1544 NINDS_000964 CC(N)Cc1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A10 mock treatment 993280.0 -178000.0 -0.87 907490.0 -90700.0 -0.54 834940.0 -193751.13793103 -1.10970817409502 -1.4552 -0.9634 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A11 compound treatment 902410.0 -269000.0 -1.32 770040.0 -228000.0 -1.36 812270.0 -216421.13793103 -1.23955042728318 -2.2584 -0.9993 1545 NINDS_000965 OC1N=C(c2ccccc2Cl)c3cc(Cl)ccc3NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A12 mock treatment 1072260.0 -99300.0 -0.49 909010.0 -89200.0 -0.53 848160.0 -180531.13793103 -1.03399072428702 -1.1835 -0.9397 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A13 compound treatment 1030030.0 -142000.0 -0.69 852100.0 -146000.0 -0.87 881120.0 -147571.13793103 -0.845212574084917 -1.389 -0.9952 1546 NINDS_000966 CNC(C)C(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A14 mock treatment 956910.0 -215000.0 -1.05 984190.0 -14000.0 -0.08 877120.0 -151571.13793103 -0.868122543769638 -1.155 -0.8467 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A15 compound treatment 882190.0 -289000.0 -1.41 955760.0 -42500.0 -0.25 898240.0 -130451.13793103 -0.747157903834312 -1.3936 -0.8607 1547 NINDS_000967 CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A16 mock treatment 1041920.0 -130000.0 -0.63 971450.0 -26800.0 -0.16 926490.0 -102201.13793103 -0.58535624293597 -0.7957 -0.9071 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A17 compound treatment 998490.0 -173000.0 -0.85 959810.0 -38400.0 -0.23 885520.0 -143171.13793103 -0.820011607431724 -1.0937 -0.9114 1548 NINDS_000968 CN1C2CCC1C(C(C2)OC(=O)c3ccccc3)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A18 mock treatment 923170.0 -248000.0 -1.21 890480.0 -108000.0 -0.64 853280.0 -175411.13793103 -1.00466596309057 -1.6508 -0.9705 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A19 compound treatment 293080.0 -879000.0 -4.29 165810.0 -832000.0 -4.95 153280.0 -875411.13793103 -5.01391065791674 -8.2309 -0.9977 3173101 NINDS_000969 CO[C@@]1(CC[C@]23C[C@@H]1C(C)(O)C(C)(C)C)[C@@H]4Oc5c6c(C[C@H]3N(CC7CC7)CC[C@@]462)ccc5O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A20 mock treatment 893080.0 -279000.0 -1.36 855150.0 -143000.0 -0.85 831150.0 -197541.13793103 -1.13141537037129 -1.9301 -0.9829 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A21 compound treatment 874530.0 -297000.0 -1.45 855680.0 -143000.0 -0.85 867200.0 -161491.13793103 -0.924939268587746 -1.8614 -0.9702 1550 NINDS_000970 CC(C)CC1(CC=C)C(=O)NC(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A22 mock treatment 891560.0 -280000.0 -1.37 850130.0 -148000.0 -0.88 904530.0 -124161.13793103 -0.711131976505088 -1.709 -0.9624 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A23 mock treatment 898610.0 -273000.0 -1.33 822800.0 -175000.0 -1.04 820250.0 -208441.13793103 -1.19384503776216 -2.0616 -0.9951 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 A24 mock treatment 987610.0 -184000.0 -0.9 830660.0 -168000.0 -1.0 907700.0 -120991.13793103 -0.692975825529947 -1.4944 -0.9894 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B01 mock treatment 1134830.0 -36800.0 -0.18 816320.0 -182000.0 -1.08 966620.0 -62071.13793103 -0.355511972074007 -0.9335 -0.8098 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B02 mock treatment 983650.0 -188000.0 -0.92 894660.0 -104000.0 -0.62 838820.0 -189871.13793103 -1.08748550350084 -1.5136 -0.976 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B03 mock treatment 1047060.0 -125000.0 -0.61 874980.0 -123000.0 -0.73 982040.0 -46651.13793103 -0.267194038939408 -0.9287 -0.9387 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B04 mock treatment 982260.0 -189000.0 -0.93 911840.0 -86400.0 -0.51 933400.0 -95291.13793103 -0.545779270305615 -1.1458 -0.9624 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B05 mock treatment 998690.0 -173000.0 -0.84 903620.0 -94600.0 -0.56 885360.0 -143331.13793103 -0.820928006219113 -1.2865 -0.9855 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B06 mock treatment 988000.0 -184000.0 -0.9 897840.0 -100000.0 -0.6 901530.0 -127161.13793103 -0.728314453768629 -1.2831 -0.9865 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B07 mock treatment 1106650.0 -64900.0 -0.32 944510.0 -53700.0 -0.32 972750.0 -55941.13793103 -0.320402443532172 -0.5526 -1.0 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B08 mock treatment 1121980.0 -49600.0 -0.24 959200.0 -39000.0 -0.23 971040.0 -57651.13793103 -0.330196455572391 -0.4646 -0.9868 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B09 mock treatment 991170.0 -180000.0 -0.88 992690.0 -5550.0 -0.03 916400.0 -112291.13793103 -0.643146641465678 -0.8993 -0.8238 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B10 mock treatment 1060100.0 -111000.0 -0.54 938320.0 -59900.0 -0.36 946600.0 -82091.13793103 -0.470176370346035 -0.7917 -0.9859 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B11 mock treatment 1090180.0 -81400.0 -0.4 904090.0 -94100.0 -0.56 949950.0 -78741.13793103 -0.450989270735082 -0.8133 -0.9898 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B12 mock treatment 1041170.0 -130000.0 -0.64 949620.0 -48600.0 -0.29 967920.0 -60771.13793103 -0.348066231926473 -0.7358 -0.9415 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B13 mock treatment 1125290.0 -46300.0 -0.23 1037280.0 39000.0 0.23 934240.0 -94451.13793103 -0.540968176671823 -0.3089 -0.4898 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B14 mock treatment 979300.0 -192000.0 -0.94 931810.0 -66400.0 -0.4 945530.0 -83161.13793103 -0.476304787236698 -1.0455 -0.9293 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B15 mock treatment 1097210.0 -74400.0 -0.36 946820.0 -51400.0 -0.31 959040.0 -69651.13793103 -0.398926364626553 -0.6167 -0.9942 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B16 mock treatment 1114990.0 -56600.0 -0.28 935870.0 -62400.0 -0.37 960890.0 -67801.13793103 -0.38833050364737 -0.598 -0.99 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B17 mock treatment 1021280.0 -150000.0 -0.73 946980.0 -51300.0 -0.3 935710.0 -92981.13793103 -0.532548762812688 -0.9075 -0.9482 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B18 mock treatment 1034120.0 -137000.0 -0.67 947290.0 -50900.0 -0.3 927360.0 -101331.13793103 -0.580373324529543 -0.8978 -0.9572 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B19 mock treatment 1079260.0 -92300.0 -0.45 1001160.0 2920.0 0.02 903360.0 -125331.13793103 -0.717833142637869 -0.6649 -0.784 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B20 mock treatment 1058480.0 -113000.0 -0.55 1020010.0 21800.0 0.13 945340.0 -83351.13793103 -0.477393010796723 -0.52 -0.701 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B21 mock treatment 1012990.0 -159000.0 -0.77 958450.0 -39800.0 -0.24 926340.0 -102351.13793103 -0.586215366799147 -0.9225 -0.9224 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B22 mock treatment 1102460.0 -69100.0 -0.34 904520.0 -93700.0 -0.56 942100.0 -86591.13793103 -0.495950086241347 -0.8031 -0.9807 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B23 mock treatment 1120060.0 -51500.0 -0.25 909950.0 -88300.0 -0.53 920230.0 -108461.13793103 -0.621210345492558 -0.8071 -0.948 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 B24 mock treatment 953800.0 -218000.0 -1.06 908160.0 -90100.0 -0.54 883840.0 -144851.13793103 -0.829633794699307 -1.4026 -0.9662 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C01 mock treatment 1015680.0 -156000.0 -0.76 872960.0 -125000.0 -0.74 919290.0 -109401.13793103 -0.626594188368468 -1.2317 -0.9964 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C02 mock treatment 1036690.0 -135000.0 -0.66 856900.0 -141000.0 -0.84 1004650.0 -24041.13793103 -0.137695435296523 -0.9453 -0.8778 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C03 compound treatment 455320.0 -716000.0 -3.5 642020.0 -356000.0 -2.12 699620.0 -329071.13793103 -1.88475244852913 -4.3316 -0.9617 1551 NINDS_000971 CCCCCc1cc(O)c(C2CC(=CCC2C(=C)C)C)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C04 mock treatment 1043760.0 -128000.0 -0.62 955800.0 -42400.0 -0.25 986010.0 -42681.13793103 -0.244455894027323 -0.6474 -0.9035 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C05 compound treatment 456260.0 -715000.0 -3.49 343860.0 -654000.0 -3.89 252830.0 -775861.13793103 -4.44373878738825 -6.8301 -0.9952 1552 NINDS_000972 CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc32)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C06 mock treatment 1056640.0 -115000.0 -0.56 1040600.0 42400.0 0.25 973990.0 -54701.13793103 -0.313300352929909 -0.3597 -0.5208 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C07 compound treatment 1065600.0 -106000.0 -0.52 1050130.0 51900.0 0.31 1191800.0 163108.86206897 0.934204771327357 0.4185 0.3764 1553 NINDS_000973 [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C08 mock treatment 1088440.0 -83200.0 -0.41 1012160.0 13900.0 0.08 937190.0 -91501.13793103 -0.524072074029342 -0.4893 -0.7323 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C09 compound treatment 1167300.0 -4290.0 -0.02 1065770.0 67500.0 0.4 915840.0 -112851.13793103 -0.646354037221539 -0.1534 -0.2016 1554 NINDS_000974 CCOC(=O)C1C2CCC(CC1OC(=O)c3ccccc3)N2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C10 mock treatment 1117830.0 -53800.0 -0.26 968840.0 -29400.0 -0.17 983690.0 -45001.13793103 -0.257743676444461 -0.4014 -0.9852 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C11 compound treatment 1225210.0 53600.0 0.26 913210.0 -85000.0 -0.51 1023000.0 -5691.13793103001 -0.0325959493678657 -0.1595 -0.2796 1555 NINDS_000975 COC(=O)C1C2CCC(CC1OC(=O)c3ccccc3)N2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C12 mock treatment 1023120.0 -148000.0 -0.73 968110.0 -30100.0 -0.18 975270.0 -53421.13793103 -0.305969162630798 -0.6989 -0.8656 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C13 compound treatment 1194720.0 23100.0 0.11 1024200.0 26000.0 0.15 1057320.0 28628.86206897 0.16397159052704 0.249 0.9884 1556 NINDS_000976 COc1ccc2C[C@@H]3C4C=C[C@H](O)[C@@H]5Oc1c2[C@@]54CCN3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C14 mock treatment 1077220.0 -94400.0 -0.46 980520.0 -17700.0 -0.11 954590.0 -74101.13793103 -0.424413705900805 -0.5721 -0.9002 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C15 compound treatment 712560.0 -459000.0 -2.24 693920.0 -304000.0 -1.81 662150.0 -366541.13793103 -2.09936158955075 -3.5517 -0.9962 1557 NINDS_000977 CCCCCc1cc(O)c2C3C=C(C)CCC3C(C)(C)Oc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C16 mock treatment 1058180.0 -113000.0 -0.55 977370.0 -20900.0 -0.12 943360.0 -85331.13793103 -0.488733445790659 -0.6737 -0.8993 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C17 compound treatment 370010.0 -802000.0 -3.92 426650.0 -572000.0 -3.4 401450.0 -627241.13793103 -3.59251886375244 -6.2977 -0.9983 1558 NINDS_000978 CCCCCc1cc(O)c2C3CC(=CCC3C(C)(C)Oc2c1)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C18 mock treatment 1096800.0 -74800.0 -0.37 969570.0 -28700.0 -0.17 906430.0 -122261.13793103 -0.700249740904845 -0.7137 -0.8832 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C19 compound treatment 1040670.0 -131000.0 -0.64 948530.0 -49700.0 -0.3 972580.0 -56111.13793103 -0.321376117243773 -0.7255 -0.9368 1559 NINDS_000979 Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C20 mock treatment 1079470.0 -92100.0 -0.45 943040.0 -55200.0 -0.33 957710.0 -70981.13793103 -0.406543929546723 -0.6841 -0.992 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C21 compound treatment 1019010.0 -153000.0 -0.75 846240.0 -152000.0 -0.9 893600.0 -135091.13793103 -0.773733468668588 -1.399 -0.9964 1560 NINDS_000980 CCNC(C)Cc1cccc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C22 mock treatment 990720.0 -181000.0 -0.88 918030.0 -80200.0 -0.48 910770.0 -117921.13793103 -0.675392423796923 -1.1755 -0.9713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C23 mock treatment 1102480.0 -69100.0 -0.34 905230.0 -93000.0 -0.55 908050.0 -120641.13793103 -0.690971203182533 -0.9132 -0.964 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 C24 mock treatment 1052510.0 -119000.0 -0.58 867360.0 -131000.0 -0.78 969850.0 -58841.13793103 -0.337012171553595 -0.9798 -0.9527 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D01 mock treatment 940480.0 -231000.0 -1.13 825360.0 -173000.0 -1.03 950990.0 -77701.13793103 -0.445032678617054 -1.5024 -0.9446 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D02 mock treatment 1079060.0 -92500.0 -0.45 986240.0 -12000.0 -0.07 946490.0 -82201.13793103 -0.470806394512365 -0.574 -0.8742 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D03 mock treatment 1087530.0 -84100.0 -0.41 960010.0 -38200.0 -0.23 1012960.0 -15731.13793103 -0.0900999732765153 -0.4204 -0.8795 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D04 mock treatment 1055590.0 -116000.0 -0.57 1012740.0 14500.0 0.09 962880.0 -65811.13793103 -0.376932793729221 -0.4951 -0.7215 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D05 mock treatment 1084180.0 -87400.0 -0.43 981500.0 -16700.0 -0.1 989010.0 -39681.13793103 -0.227273416763782 -0.4353 -0.8812 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D06 mock treatment 1255300.0 83700.0 0.41 1017390.0 19200.0 0.11 970250.0 -58441.13793103 -0.334721174585123 0.1086 0.2009 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D07 mock treatment 1089840.0 -81800.0 -0.4 974400.0 -23800.0 -0.14 891880.0 -136811.13793103 -0.783584755633018 -0.7649 -0.8586 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D08 mock treatment 1087580.0 -84000.0 -0.41 994630.0 -3610.0 -0.02 957990.0 -70701.13793103 -0.404940231668793 -0.4832 -0.8374 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D09 mock treatment 1125730.0 -45900.0 -0.22 968180.0 -30100.0 -0.18 941650.0 -87041.13793103 -0.498527457830878 -0.5204 -0.9049 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D10 mock treatment 1038490.0 -133000.0 -0.65 1011520.0 13300.0 0.08 946790.0 -81901.13793103 -0.469088146786011 -0.6007 -0.7455 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D11 mock treatment 1081280.0 -90300.0 -0.44 1033460.0 35200.0 0.21 908240.0 -120451.13793103 -0.689882979622509 -0.5321 -0.6295 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D12 mock treatment 1453190.0 282000.0 1.38 1059040.0 60800.0 0.36 1147760.0 119068.86206897 0.68196600509858 1.3968 0.8854 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D13 mock treatment 1102520.0 -69100.0 -0.34 1204680.0 206000.0 1.23 1005810.0 -22881.13793103 -0.131051544087954 0.4383 0.3424 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D14 mock treatment 1088040.0 -83600.0 -0.41 1012480.0 14200.0 0.08 965800.0 -62891.13793103 -0.360208515859375 -0.3948 -0.7165 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D15 mock treatment 1108220.0 -63400.0 -0.31 971610.0 -26600.0 -0.16 992490.0 -36201.13793103 -0.207341743138075 -0.3899 -0.963 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D16 mock treatment 1187310.0 15700.0 0.08 1004870.0 6630.0 0.04 1004160.0 -24531.13793103 -0.140501906582901 -0.014 -0.085 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D17 mock treatment 1148660.0 -22900.0 -0.11 937920.0 -60300.0 -0.36 951840.0 -76851.13793103 -0.440164310059051 -0.5259 -0.9087 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D18 mock treatment 1241620.0 70000.0 0.34 940900.0 -57300.0 -0.34 963760.0 -64931.13793103 -0.371892600398583 -0.214 -0.3511 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D19 mock treatment 1115360.0 -56200.0 -0.27 1033120.0 34900.0 0.21 1033930.0 5238.86206896999 0.0300055427956342 -0.0215 -0.0624 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D20 mock treatment 1103070.0 -68500.0 -0.33 909120.0 -89100.0 -0.53 927470.0 -101221.13793103 -0.579743300363213 -0.834 -0.9767 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D21 mock treatment 1038730.0 -133000.0 -0.65 950530.0 -47700.0 -0.28 1011010.0 -17681.13793103 -0.101268583497817 -0.5971 -0.8343 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D22 mock treatment 998480.0 -173000.0 -0.85 1019680.0 21400.0 0.13 956870.0 -71821.13793103 -0.411355023180514 -0.6522 -0.6872 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D23 mock treatment 1026240.0 -145000.0 -0.71 926770.0 -71500.0 -0.42 945150.0 -83541.13793103 -0.478481234356747 -0.9316 -0.9745 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 D24 mock treatment 1051260.0 -120000.0 -0.59 913570.0 -84700.0 -0.5 1108550.0 79858.86206897 0.457391027264103 -0.3661 -0.4071 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E01 mock treatment 1100800.0 -70800.0 -0.35 978130.0 -20100.0 -0.12 1008370.0 -20321.13793103 -0.116389163489733 -0.3359 -0.8747 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E02 mock treatment 1151100.0 -20500.0 -0.1 958160.0 -40100.0 -0.24 1094110.0 65418.86206897 0.374686036702261 0.0209 0.0459 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E03 compound treatment 1126880.0 -44700.0 -0.22 1068590.0 70400.0 0.42 987770.0 -40921.13793103 -0.234375507366045 -0.0199 -0.0378 1561 NINDS_000981 CN1C(=O)CN=C(c2ccccc2F)c3cc(ccc13)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E04 mock treatment 1179840.0 8250.0 0.04 1046440.0 48200.0 0.29 1005510.0 -23181.13793103 -0.132769791814308 0.1121 0.352 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E05 compound treatment 1152050.0 -19500.0 -0.1 1059920.0 61700.0 0.37 939310.0 -89381.13793103 -0.511929790096439 -0.1389 -0.2181 1562 NINDS_000982 CN1CC[C@]23[C@H]4Oc5c3c(C[C@@H]1C2CCC4=O)ccc5O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E06 mock treatment 1434560.0 263000.0 1.28 1347200.0 349000.0 2.08 1013480.0 -15211.13793103 -0.0871216772175016 1.8896 0.7737 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E07 compound treatment 1310640.0 139000.0 0.68 1158630.0 160000.0 0.95 1278290.0 249598.86206897 1.42957559083524 1.7683 0.9569 1563 NINDS_000983 CCOC(=O)C1(CCN(C)CC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E08 mock treatment 1214650.0 43100.0 0.21 1081320.0 83100.0 0.49 954800.0 -73891.13793103 -0.423210932492358 0.1624 0.2375 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E09 compound treatment 1255110.0 83500.0 0.41 1100770.0 103000.0 0.61 974100.0 -54591.13793103 -0.312670328763579 0.4071 0.5104 1564 NINDS_000984 COc1cc(CCN)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E10 mock treatment 1144880.0 -26700.0 -0.13 1000480.0 2240.0 0.01 955430.0 -73261.13793103 -0.419602612267014 -0.3099 -0.7049 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E11 compound treatment 1208420.0 36800.0 0.18 992990.0 -5250.0 -0.03 918440.0 -110251.13793103 -0.631462556926471 -0.2787 -0.424 1565 NINDS_000985 CN1CC[C@]23[C@H]4Oc5c3c(C[C@@H]1C2C=C[C@H]4O)ccc5O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E12 mock treatment 1207960.0 36400.0 0.18 1025440.0 27200.0 0.16 1133050.0 104358.86206897 0.597714591583019 0.5411 0.8399 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E13 compound treatment 1167160.0 -4430.0 -0.02 1004240.0 6000.0 0.04 967480.0 -61211.13793103 -0.350586328591792 -0.1943 -0.5504 1566 NINDS_000986 OC1N=C(c2ccccc2)c3cc(Cl)ccc3NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E14 mock treatment 1256800.0 85200.0 0.42 1190080.0 192000.0 1.14 1074010.0 45318.86206897 0.259563439036538 1.0489 0.8446 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E15 compound treatment 1135600.0 -36000.0 -0.18 1008580.0 10300.0 0.06 961890.0 -66801.13793103 -0.38260301122619 -0.2869 -0.6742 1567 NINDS_000987 CCC1(C(=O)NC(=O)NC1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E16 mock treatment 1107870.0 -63700.0 -0.31 1035100.0 36900.0 0.22 1009130.0 -19561.13793103 -0.112036269249636 -0.1179 -0.297 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E17 compound treatment 1119960.0 -51600.0 -0.25 983400.0 -14800.0 -0.09 997770.0 -30921.13793103 -0.177100583154243 -0.2988 -0.9321 1568 NINDS_000988 CNC(C)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E18 mock treatment 1216440.0 44800.0 0.22 1228960.0 231000.0 1.37 995390.0 -33301.13793103 -0.190732015116652 0.8085 0.5765 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E19 compound treatment 1083800.0 -87800.0 -0.43 1172080.0 174000.0 1.03 1082450.0 53758.86206897 0.307903475071299 0.527 0.454 1569 NINDS_000989 CN1C(=O)C(O)N=C(c2ccccc2)c3cc(Cl)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E20 mock treatment 1111430.0 -60200.0 -0.29 979280.0 -19000.0 -0.11 1033990.0 5298.86206896999 0.030349192340905 -0.2173 -0.687 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E21 compound treatment 1078650.0 -92900.0 -0.45 937600.0 -60600.0 -0.36 956360.0 -72331.13793103 -0.414276044315316 -0.7095 -0.9957 1570 NINDS_000990 CCCC(C)C1(CC=C)C(=O)NC(=NC1=O)S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E22 mock treatment 1193960.0 22400.0 0.11 973250.0 -25000.0 -0.15 1020760.0 -7931.13793103001 -0.0454255323913095 -0.0489 -0.2576 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E23 mock treatment 1055930.0 -116000.0 -0.57 1023200.0 25000.0 0.15 953350.0 -75341.13793103 -0.431515796503069 -0.4897 -0.6742 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 E24 mock treatment 1045400.0 -126000.0 -0.62 1046170.0 47900.0 0.29 929440.0 -99251.13793103 -0.568460140293488 -0.5196 -0.5866 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F01 mock treatment 1014330.0 -157000.0 -0.77 895420.0 -103000.0 -0.61 981620.0 -47071.13793103 -0.269599585756304 -0.9523 -0.9352 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F02 mock treatment 1062250.0 -109000.0 -0.53 973800.0 -24400.0 -0.15 980740.0 -47951.13793103 -0.274639779086942 -0.5509 -0.8914 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F03 mock treatment 1137760.0 -33800.0 -0.17 1064960.0 66700.0 0.4 904570.0 -124121.13793103 -0.710902876808241 -0.2768 -0.3332 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F04 mock treatment 1091870.0 -79700.0 -0.39 963380.0 -34900.0 -0.21 1021240.0 -7451.13793103001 -0.0426763360291429 -0.3692 -0.8329 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F05 mock treatment 1152520.0 -19100.0 -0.09 990990.0 -7250.0 -0.04 982780.0 -45911.13793103 -0.262955694547735 -0.2305 -0.8166 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F06 mock treatment 1274510.0 103000.0 0.5 984640.0 -13600.0 -0.08 937320.0 -91371.13793103 -0.523327500014588 -0.0585 -0.0801 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F07 mock treatment 1158090.0 -13500.0 -0.07 991400.0 -6840.0 -0.04 978630.0 -50061.13793103 -0.286724788095633 -0.2271 -0.7646 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F08 mock treatment 1174190.0 2600.0 0.01 981550.0 -16700.0 -0.1 978940.0 -49751.13793103 -0.284949265445067 -0.2145 -0.7102 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F09 mock treatment 1139840.0 -31800.0 -0.16 1176590.0 178000.0 1.06 1112760.0 84068.86206897 0.481503770357272 0.8007 0.6815 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F10 mock treatment 1206900.0 35300.0 0.17 1008870.0 10600.0 0.06 972510.0 -56181.13793103 -0.321777041713256 -0.0497 -0.1341 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F11 mock treatment 1115260.0 -56300.0 -0.28 1082410.0 84200.0 0.5 1016370.0 -12321.13793103 -0.0705692241202907 0.0893 0.1552 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F12 mock treatment 1502880.0 331000.0 1.62 997450.0 -788.0 0.0 1287520.0 258828.86206897 1.48244034588273 1.7877 0.8145 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F13 mock treatment 1160800.0 -10800.0 -0.05 1031060.0 32800.0 0.2 999680.0 -29011.13793103 -0.166161072629789 -0.0137 -0.0523 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F14 mock treatment 1139320.0 -32300.0 -0.16 1395160.0 397000.0 2.36 1006780.0 -21911.13793103 -0.125495876439409 1.1992 0.5062 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F15 mock treatment 1086050.0 -85500.0 -0.42 964100.0 -34100.0 -0.2 946560.0 -82131.13793103 -0.470405470042883 -0.6301 -0.953 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F16 mock treatment 1094360.0 -77200.0 -0.38 978900.0 -19300.0 -0.11 972050.0 -56641.13793103 -0.324411688226999 -0.4716 -0.9233 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F17 mock treatment 1070910.0 -101000.0 -0.49 967040.0 -31200.0 -0.19 1213690.0 184998.86206897 1.05957958042699 0.2206 0.1865 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F18 mock treatment 1095540.0 -76100.0 -0.37 1072320.0 74100.0 0.44 1025610.0 -3081.13793103001 -0.0176471941485853 0.0296 0.0514 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F19 mock treatment 1155540.0 -16100.0 -0.08 958690.0 -39500.0 -0.24 1008970.0 -19721.13793103 -0.112952668037024 -0.2463 -0.904 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F20 mock treatment 1096090.0 -75500.0 -0.37 939360.0 -58900.0 -0.35 944410.0 -84281.13793103 -0.48271957874842 -0.6938 -0.9895 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F21 mock treatment 1056090.0 -116000.0 -0.56 954210.0 -44000.0 -0.26 968080.0 -60611.13793103 -0.347149833139084 -0.6774 -0.9509 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F22 mock treatment 1248340.0 76700.0 0.37 968930.0 -29300.0 -0.17 967680.0 -61011.13793103 -0.349440830107556 -0.0859 -0.1586 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F23 mock treatment 1225600.0 54000.0 0.26 1002050.0 3810.0 0.02 1074360.0 45668.86206897 0.261568061383951 0.3164 0.8501 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 F24 mock treatment 1237610.0 66000.0 0.32 914240.0 -84000.0 -0.5 970340.0 -58351.13793103 -0.334205700267217 -0.2951 -0.4327 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G01 mock treatment 1148800.0 -22800.0 -0.11 964240.0 -34000.0 -0.2 1092250.0 63558.86206897 0.364032900798865 0.0292 0.0676 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G02 mock treatment 1134940.0 -36700.0 -0.18 1015160.0 16900.0 0.1 1101790.0 73098.86206897 0.418673178496925 0.1964 0.4212 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G03 compound treatment 1070240.0 -101000.0 -0.5 1046480.0 48200.0 0.29 969130.0 -59561.13793103 -0.341135966096845 -0.3172 -0.4761 1571 NINDS_000991 CC(N)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G04 mock treatment 1074210.0 -97400.0 -0.48 998900.0 662.0 0.0 1040080.0 11388.86206897 0.0652296211858926 -0.2348 -0.4888 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G05 compound treatment 1280030.0 108000.0 0.53 1116800.0 119000.0 0.71 1055520.0 26828.86206897 0.153662104168915 0.8016 0.8955 1572 NINDS_000992 CCCC(C)C1(CC)C(=O)NC(=NC1=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G06 mock treatment 1191160.0 19600.0 0.1 1026160.0 27900.0 0.17 1006740.0 -21951.13793103 -0.125724976136256 0.0785 0.3424 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G07 compound treatment 1314560.0 143000.0 0.7 1297020.0 299000.0 1.78 1056410.0 27718.86206897 0.158759572423766 1.5207 0.7938 1573 NINDS_000993 CCCC(C)C1(CC)C(=O)NC(=NC1=O)S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G08 mock treatment 1157640.0 -14000.0 -0.07 1087770.0 89500.0 0.53 990140.0 -38551.13793103 -0.220801350327848 0.1405 0.2421 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G09 compound treatment 1425250.0 254000.0 1.24 1069520.0 71300.0 0.42 957400.0 -71291.13793103 -0.408319452197289 0.7245 0.5281 1574 NINDS_000994 CCC1(CCC(C)C)C(=O)NC(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G10 mock treatment 1237990.0 66400.0 0.32 1085940.0 87700.0 0.52 1027690.0 -1001.13793103001 -0.00573400991253045 0.4851 0.7898 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G11 compound treatment 1317560.0 146000.0 0.71 1073450.0 75200.0 0.45 1001570.0 -27121.13793103 -0.155336111953758 0.5803 0.6779 1575 NINDS_000995 CNC1=Nc2ccc(Cl)cc2C(=[N+]([O-])C1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G12 mock treatment 1512450.0 341000.0 1.67 1045130.0 46900.0 0.28 1264160.0 235468.86206897 1.34864612292396 1.9011 0.8797 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G13 compound treatment 132690.0 -1040000.0 -5.08 123300.0 -875000.0 -5.2 92740.0 -935951.13793103 -5.36065304909499 -9.0294 -0.9998 1576 NINDS_000996 CC(=CCc1c(O)c2c(=O)c(coc2c3C=CC(C)(C)Oc13)c4ccc(O)c(O)c4)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G14 mock treatment 1134930.0 -36700.0 -0.18 1219060.0 221000.0 1.31 934080.0 -94611.13793103 -0.541884575459212 0.3419 0.2388 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G15 compound treatment 839280.0 -332000.0 -1.62 767690.0 -231000.0 -1.37 770420.0 -258271.13793103 -1.47924598510957 -2.583 -0.9976 1577 NINDS_000997 OCC(S)CS 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G16 mock treatment 1197660.0 26100.0 0.13 952160.0 -46100.0 -0.27 1013310.0 -15381.13793103 -0.0880953509291022 -0.1355 -0.4306 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G17 compound treatment 1176870.0 5280.0 0.03 867810.0 -130000.0 -0.78 935870.0 -92821.13793103 -0.531632364025299 -0.7399 -0.7865 1578 NINDS_000998 CC1=NCCc2c1[nH]c3cc(O)ccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G18 mock treatment 1143260.0 -28300.0 -0.14 997860.0 -378.0 0.0 1033930.0 5238.86206896999 0.0300055427956342 -0.0639 -0.4511 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G19 compound treatment 498560.0 -673000.0 -3.29 426900.0 -571000.0 -3.4 417280.0 -611411.13793103 -3.50185265872516 -5.8819 -0.9997 1579 NINDS_000999 CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G20 mock treatment 1173800.0 2210.0 0.01 1004380.0 6140.0 0.04 1100170.0 71478.86206897 0.409394640774613 0.2637 0.6413 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G21 compound treatment 1237120.0 65500.0 0.32 961960.0 -36300.0 -0.22 1053050.0 24358.86206897 0.1395151978886 0.1408 0.3431 1000143 NINDS_001000 NC(Cn1ccc(=O)c(O)c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G22 mock treatment 1061640.0 -110000.0 -0.54 1007090.0 8850.0 0.05 975800.0 -52891.13793103 -0.302933591647573 -0.4547 -0.7345 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G23 mock treatment 998140.0 -173000.0 -0.85 942530.0 -55700.0 -0.33 1005520.0 -23171.13793103 -0.132712516890096 -0.7572 -0.8234 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 G24 mock treatment 1215840.0 44200.0 0.22 1015680.0 17400.0 0.1 974560.0 -54131.13793103 -0.310035682249836 0.0057 0.0145 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H01 mock treatment 992450.0 -179000.0 -0.88 977930.0 -20300.0 -0.12 871100.0 -157591.13793103 -0.902602048145143 -1.0962 -0.8679 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H02 mock treatment 1196980.0 25400.0 0.12 1086020.0 87800.0 0.52 1034130.0 5438.86206896999 0.0311510412798703 0.391 0.7275 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H03 mock treatment 1140590.0 -31000.0 -0.15 969980.0 -28300.0 -0.17 957600.0 -71091.13793103 -0.407173953713053 -0.4196 -0.9007 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H04 mock treatment 1140800.0 -30800.0 -0.15 962500.0 -35700.0 -0.21 1007130.0 -21561.13793103 -0.123491254091996 -0.2809 -0.9746 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H05 mock treatment 1222040.0 50400.0 0.25 1044910.0 46700.0 0.28 1007230.0 -21461.13793103 -0.122918504849878 0.2316 0.5922 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H06 mock treatment 1195800.0 24200.0 0.12 1058330.0 60100.0 0.36 944080.0 -84611.13793103 -0.48460965124741 -0.0052 -0.0085 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H07 mock treatment 1197440.0 25800.0 0.13 1215940.0 218000.0 1.29 1013320.0 -15371.13793103 -0.0880380760048904 0.7695 0.5902 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H08 mock treatment 1307210.0 136000.0 0.66 1061080.0 62800.0 0.37 992020.0 -36671.13793103 -0.210033664576029 0.477 0.6045 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H09 mock treatment 1165920.0 -5670.0 -0.03 1011910.0 13700.0 0.08 951680.0 -77011.13793103 -0.44108070884644 -0.2237 -0.4979 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H10 mock treatment 1373210.0 202000.0 0.99 1040840.0 42600.0 0.25 1019250.0 -9441.13793103001 -0.0540740459472916 0.6838 0.6713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H11 mock treatment 1185830.0 14200.0 0.07 1109280.0 111000.0 0.66 1217390.0 188698.86206897 1.08077130238536 1.0454 0.8241 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H12 mock treatment 1398990.0 227000.0 1.11 1238370.0 240000.0 1.43 1330930.0 302238.86206897 1.73107079188616 2.4653 0.9845 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H13 mock treatment 1132840.0 -38800.0 -0.19 976720.0 -21500.0 -0.13 991840.0 -36851.13793103 -0.211064613211842 -0.3051 -0.9806 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H14 mock treatment 1191060.0 19500.0 0.1 1073640.0 75400.0 0.45 1010080.0 -18611.13793103 -0.106595151449514 0.2522 0.536 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H15 mock treatment 1165530.0 -6060.0 -0.03 967610.0 -30600.0 -0.18 979530.0 -49161.13793103 -0.28157004491657 -0.2848 -0.8461 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H16 mock treatment 1390750.0 219000.0 1.07 1116710.0 118000.0 0.7 1258130.0 229438.86206897 1.31410934362424 1.7836 0.9717 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H17 mock treatment 1152100.0 -19500.0 -0.1 1014200.0 16000.0 0.09 1031680.0 2988.86206896999 0.0171186848479787 0.0097 0.0715 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H18 mock treatment 1132260.0 -39300.0 -0.19 1114110.0 116000.0 0.69 1103970.0 75278.86206897 0.431159111975098 0.5358 0.6415 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H19 mock treatment 1213060.0 41500.0 0.2 1037340.0 39100.0 0.23 1030560.0 1868.86206896999 0.0107038933362568 0.2574 0.8341 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H20 mock treatment 1121930.0 -49700.0 -0.24 971530.0 -26700.0 -0.16 1039800.0 11108.86206897 0.0636259233079622 -0.1951 -0.657 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H21 mock treatment 1160610.0 -11000.0 -0.05 913280.0 -85000.0 -0.51 1060100.0 31408.86206897 0.179894019457921 -0.2188 -0.406 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H22 mock treatment 1356830.0 185000.0 0.91 939160.0 -59100.0 -0.35 1108920.0 80228.86206897 0.45951019945994 0.585 0.5446 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H23 mock treatment 1303050.0 131000.0 0.64 964740.0 -33500.0 -0.2 1133440.0 104748.86206897 0.599948313627279 0.6022 0.6682 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 H24 mock treatment 1288960.0 117000.0 0.57 1004320.0 6080.0 0.04 1112970.0 84278.86206897 0.48270654376572 0.6306 0.8404 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I01 mock treatment 1044410.0 -127000.0 -0.62 999000.0 762.0 0.0 1083710.0 55018.86206897 0.315120115521986 -0.1742 -0.25 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I02 mock treatment 1152480.0 -19100.0 -0.09 854320.0 -144000.0 -0.86 1083860.0 55168.86206897 0.315979239385163 -0.3656 -0.3987 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I03 compound treatment 862520.0 -309000.0 -1.51 797520.0 -201000.0 -1.19 808320.0 -220371.13793103 -1.26217402234684 -2.2897 -0.9948 3103678 NINDS_001001 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I04 mock treatment 1288700.0 117000.0 0.57 1011220.0 13000.0 0.08 984640.0 -44051.13793103 -0.252302558644339 0.2292 0.3638 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I05 compound treatment 1333000.0 161000.0 0.79 1064000.0 65800.0 0.39 992350.0 -36341.13793103 -0.20814359207704 0.5609 0.6201 1581 NINDS_001002 CNC(=N)NCCCC(N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I06 mock treatment 1154740.0 -16900.0 -0.08 1074760.0 76500.0 0.46 948480.0 -80211.13793103 -0.459408684594217 -0.0501 -0.0768 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I07 compound treatment 1335950.0 164000.0 0.8 1178400.0 180000.0 1.07 1135520.0 106828.86206897 0.611861497863334 1.4354 0.9751 1582 NINDS_001003 O=C1CCO1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I08 mock treatment 1135200.0 -36400.0 -0.18 1029380.0 31100.0 0.19 971120.0 -57571.13793103 -0.329738256178696 -0.1861 -0.4454 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I09 compound treatment 1166320.0 -5270.0 -0.03 964480.0 -33800.0 -0.2 930040.0 -98651.13793103 -0.56502364484078 -0.457 -0.7614 1583 NINDS_001004 COc1ccc(/C=C/c2cc(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I10 mock treatment 1181360.0 9770.0 0.05 1074190.0 76000.0 0.45 960800.0 -67891.13793103 -0.388845977965276 0.0638 0.1067 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I11 compound treatment 1265380.0 93800.0 0.46 998480.0 242.0 0.0 1012420.0 -16271.13793103 -0.0931928191839526 0.2116 0.4525 1584 NINDS_001005 NCCCCC(N)C(=O)NCC(=O)NC(Cc1c[nH]cn1)C(=O)NC(CCCCN)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I12 mock treatment 1470750.0 299000.0 1.46 1012160.0 13900.0 0.08 1292240.0 263548.86206897 1.5094741101107 1.7632 0.8385 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I13 compound treatment 1100330.0 -71300.0 -0.35 872930.0 -125000.0 -0.75 895560.0 -133131.13793103 -0.762507583523075 -1.0715 -0.9553 1585 NINDS_001006 CC(C)c1ccc(C)c2ccc(C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I14 mock treatment 1112370.0 -59200.0 -0.29 951400.0 -46800.0 -0.28 1258660.0 229968.86206897 1.31714491460747 0.4326 0.3141 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I15 compound treatment 964160.0 -207000.0 -1.01 514660.0 -484000.0 -2.88 480190.0 -548501.13793103 -3.14153611050871 -4.0592 -0.9272 1586 NINDS_001007 NCCCCNCCCN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I16 mock treatment 1153390.0 -18200.0 -0.09 1007470.0 9230.0 0.05 983450.0 -45241.13793103 -0.259118274625544 -0.1693 -0.6058 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I17 compound treatment 1385370.0 214000.0 1.04 934600.0 -63600.0 -0.38 1335090.0 306398.86206897 1.75489716035827 1.3977 0.673 1587 NINDS_001008 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)[C@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)C[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I18 mock treatment 1269120.0 97500.0 0.48 970740.0 -27500.0 -0.16 1040960.0 12268.86206897 0.0702698145165312 0.2213 0.435 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I19 compound treatment 1243150.0 71600.0 0.35 922880.0 -75400.0 -0.45 990790.0 -37901.13793103 -0.217078480254081 -0.1822 -0.2995 1588 NINDS_001009 CC(=O)C1C(=O)C=C2Oc3c(c(O)c(C)c(O)c3C(=O)C)C2(C)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I20 mock treatment 1042850.0 -129000.0 -0.63 1101940.0 104000.0 0.62 951520.0 -77171.13793103 -0.441997107633829 -0.2623 -0.2662 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I21 compound treatment 1284880.0 113000.0 0.55 888610.0 -110000.0 -0.65 974920.0 -53771.13793103 -0.307973784978211 -0.2346 -0.2581 1589 NINDS_001010 CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc2ccc(O)cc2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I22 mock treatment 1118400.0 -53200.0 -0.26 1023150.0 24900.0 0.15 1086760.0 58068.86206897 0.332588967406586 0.1275 0.285 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I23 mock treatment 1200530.0 28900.0 0.14 977850.0 -20400.0 -0.12 1029290.0 598.862068969989 0.00342997796135793 0.0136 0.073 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 I24 mock treatment 1154560.0 -17000.0 -0.08 969480.0 -28800.0 -0.17 1009920.0 -18771.13793103 -0.107511550236903 -0.2089 -0.956 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J01 mock treatment 1090510.0 -81100.0 -0.4 932160.0 -66100.0 -0.39 1079940.0 51248.86206897 0.293527469094137 -0.2861 -0.4538 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J02 mock treatment 1222520.0 50900.0 0.25 1003780.0 5540.0 0.03 1099600.0 70908.86206897 0.40612997009454 0.3972 0.8319 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J03 mock treatment 1157090.0 -14500.0 -0.07 1013860.0 15600.0 0.09 1002080.0 -26611.13793103 -0.152415090818956 -0.0753 -0.392 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J04 mock treatment 1333040.0 161000.0 0.79 1055280.0 57000.0 0.34 1056480.0 27788.86206897 0.159160496893248 0.7431 0.851 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J05 mock treatment 1327930.0 156000.0 0.76 1072480.0 74200.0 0.44 1025920.0 -2771.13793103001 -0.0158716714980195 0.6867 0.7783 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J06 mock treatment 1267680.0 96100.0 0.47 1119300.0 121000.0 0.72 1144030.0 115338.86206897 0.660602458367578 1.0681 0.9853 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J07 mock treatment 1231950.0 60400.0 0.29 1054160.0 55900.0 0.33 1035530.0 6838.86206896999 0.0391695306695226 0.3849 0.8626 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J08 mock treatment 1283720.0 112000.0 0.55 1060540.0 62300.0 0.37 1053000.0 24308.86206897 0.139228823267541 0.6106 0.9034 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J09 mock treatment 1323950.0 152000.0 0.74 1059920.0 61700.0 0.37 1100010.0 71318.86206897 0.408478241987224 0.8774 0.9486 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J10 mock treatment 1251940.0 80300.0 0.39 1136560.0 138000.0 0.82 988900.0 -39791.13793103 -0.227903440930112 0.57 0.6067 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J11 mock treatment 1224690.0 53100.0 0.26 1011960.0 13700.0 0.08 1018660.0 -10031.13793103 -0.0574532664757879 0.1637 0.589 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J12 mock treatment 1569800.0 398000.0 1.95 1003720.0 5480.0 0.03 1272800.0 244108.86206897 1.39813165744296 1.9493 0.8135 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J13 mock treatment 1475060.0 303000.0 1.48 1066460.0 68200.0 0.41 1325890.0 297198.86206897 1.70220423008341 2.073 0.9038 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J14 mock treatment 1353890.0 182000.0 0.89 980530.0 -17700.0 -0.11 1136930.0 108238.86206897 0.619937262177198 0.8113 0.7442 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J15 mock treatment 1258580.0 87000.0 0.42 1012260.0 14000.0 0.08 1088610.0 59918.86206897 0.343184828385769 0.4916 0.8897 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J16 mock treatment 1221280.0 49700.0 0.24 1020480.0 22200.0 0.13 1040760.0 12068.86206897 0.0691243160322952 0.2564 0.8999 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J17 mock treatment 1229070.0 57500.0 0.28 994160.0 -4080.0 -0.02 1092680.0 63988.86206897 0.366495722539973 0.3597 0.778 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J18 mock treatment 846650.0 -325000.0 -1.59 765920.0 -232000.0 -1.38 1182090.0 153398.86206897 0.878590819917697 -1.207 -0.5292 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J19 mock treatment 1152860.0 -18700.0 -0.09 980280.0 -18000.0 -0.11 1050470.0 21778.86206897 0.124738267441955 -0.0425 -0.226 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J20 mock treatment 1264540.0 92900.0 0.45 989570.0 -8670.0 -0.05 1090200.0 61508.86206897 0.352291541335446 0.4358 0.7553 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J21 mock treatment 1128320.0 -43300.0 -0.21 1011730.0 13500.0 0.08 1048680.0 19988.86206897 0.114486056008043 -0.0097 -0.0381 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J22 mock treatment 1426820.0 255000.0 1.25 997210.0 -1030.0 -0.01 1141950.0 113258.86206897 0.648689274131523 1.0909 0.7761 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J23 mock treatment 1313570.0 142000.0 0.69 926760.0 -71500.0 -0.43 1225680.0 196988.86206897 1.12825221455694 0.8065 0.5798 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 J24 mock treatment 1241960.0 70400.0 0.34 1063950.0 65700.0 0.39 1147390.0 118698.86206897 0.679846832902743 0.8166 0.9538 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K01 mock treatment 1060160.0 -111000.0 -0.54 1101460.0 103000.0 0.61 1102400.0 73708.86206897 0.422166948873845 0.2838 0.3076 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K02 mock treatment 1156350.0 -15200.0 -0.07 1097330.0 99100.0 0.59 973840.0 -54851.13793103 -0.314159476793086 0.1158 0.1724 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K03 compound treatment 1064190.0 -107000.0 -0.52 999000.0 762.0 0.0 1016250.0 -12441.13793103 -0.0712565232108323 -0.3415 -0.6448 1590 NINDS_001011 CC(C)(C)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K04 mock treatment 1231430.0 59800.0 0.29 1022240.0 24000.0 0.14 1039730.0 11038.86206897 0.0632249988384796 0.2877 0.8681 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K05 compound treatment 1307370.0 136000.0 0.66 1085610.0 87400.0 0.52 1268590.0 239898.86206897 1.37401891434979 1.4763 0.9159 1591 NINDS_001012 CC(C)C[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K06 mock treatment 1296400.0 125000.0 0.61 1047160.0 48900.0 0.29 1259410.0 230718.86206897 1.32144053392335 1.2829 0.8644 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K07 compound treatment 1374840.0 203000.0 0.99 1035320.0 37100.0 0.22 1179400.0 150708.86206897 0.863183865304723 1.199 0.8987 1000144 NINDS_001013 CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)OC2[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K08 mock treatment 1257570.0 86000.0 0.42 1077320.0 79100.0 0.47 1011860.0 -16831.13793103 -0.0964002149398135 0.4584 0.7186 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K09 compound treatment 1411060.0 239000.0 1.17 1055910.0 57700.0 0.34 1223620.0 194928.86206897 1.11645358016931 1.5181 0.9183 3173223 NINDS_001014 NC[C@@H]1O[C@H](O[C@H]2[C@@H](O)C(O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4N)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K10 mock treatment 1170980.0 -614.0 0.0 1212280.0 214000.0 1.27 1002020.0 -26671.13793103 -0.152758740364227 0.6449 0.5031 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K11 compound treatment 549650.0 -622000.0 -3.04 509560.0 -489000.0 -2.91 517990.0 -510701.13793103 -2.92503689698809 -5.1209 -0.9998 382 NINDS_001015 NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K12 mock treatment 1368190.0 197000.0 0.96 1283150.0 285000.0 1.69 1054050.0 25358.86206897 0.14524269030978 1.6166 0.8278 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K13 compound treatment 1408380.0 237000.0 1.16 940800.0 -57400.0 -0.34 1159630.0 130938.86206897 0.749951340137989 0.9037 0.6362 1594 NINDS_001016 N[C@@H](CCCNC(=N)N[N+](=O)[O-])C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K14 mock treatment 1198190.0 26600.0 0.13 1041170.0 42900.0 0.26 1094360.0 65668.86206897 0.376117909807556 0.4396 0.9297 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K15 compound treatment 1249170.0 77600.0 0.38 952490.0 -45700.0 -0.27 1002340.0 -26351.13793103 -0.150925942789449 -0.0254 -0.0517 1595 NINDS_001017 CCCCCCCCCCCCCCCCCC(=O)OC(CC(=O)O)C[N+](C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K16 mock treatment 1166560.0 -5030.0 -0.02 905220.0 -93000.0 -0.55 1003570.0 -25121.13793103 -0.143881127111398 -0.4166 -0.7283 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K17 compound treatment 1314200.0 143000.0 0.7 961360.0 -36900.0 -0.22 1218730.0 190038.86206897 1.08844614222974 0.9041 0.6897 419 NINDS_001018 CC1=NN(C(=O)C1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K18 mock treatment 1196650.0 25100.0 0.12 1042810.0 44600.0 0.27 1108820.0 80128.86206897 0.458937450217822 0.4887 0.8984 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K19 compound treatment 1252580.0 81000.0 0.4 936870.0 -61400.0 -0.36 1083450.0 54758.86206897 0.313630967492479 0.1988 0.3192 1596 NINDS_001019 CCOc1ccccc1OCC2CNCCO2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K20 mock treatment 1380130.0 209000.0 1.02 971060.0 -27200.0 -0.16 1331710.0 303018.86206897 1.73553823597468 1.4969 0.7414 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K21 compound treatment 70350.0 -1100000.0 -5.38 52480.0 -946000.0 -5.62 52120.0 -976571.13793103 -5.59330379124333 -9.5827 -0.9998 1597 NINDS_001020 CC(=CCCC1(C)Oc2c(CC=C(C)C)c3OC4(C5CC6C=C4C(=O)c3c(O)c2C=C1)C(C/C=C(/C)\C(=O)O)(OC5(C)C)C6=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K22 mock treatment 1295290.0 124000.0 0.6 1002720.0 4480.0 0.03 1078640.0 49948.86206897 0.286081728946602 0.5295 0.7912 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K23 mock treatment 1135720.0 -35900.0 -0.18 1018840.0 20600.0 0.12 976260.0 -52431.13793103 -0.30029894513383 -0.2038 -0.5529 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 K24 mock treatment 1231450.0 59900.0 0.29 908860.0 -89400.0 -0.53 1139150.0 110458.86206897 0.632652295352218 0.2272 0.2593 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L01 mock treatment 1061220.0 -110000.0 -0.54 1095290.0 97100.0 0.58 935420.0 -93271.13793103 -0.534209735614831 -0.2866 -0.3005 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L02 mock treatment 1181070.0 9480.0 0.05 985680.0 -12600.0 -0.07 1192670.0 163978.86206897 0.939187689733784 0.5259 0.5575 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L03 mock treatment 1375910.0 204000.0 1.0 1019620.0 21400.0 0.13 1228220.0 199528.86206897 1.14280004530674 1.3095 0.86 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L04 mock treatment 1215630.0 44000.0 0.22 1059080.0 60800.0 0.36 1096930.0 68238.86206897 0.390837565329989 0.5588 0.9727 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L05 mock treatment 1258290.0 86700.0 0.42 1023610.0 25400.0 0.15 1044890.0 16198.86206897 0.0927788597317696 0.3852 0.8391 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L06 mock treatment 1534360.0 363000.0 1.77 1125990.0 128000.0 0.76 1054830.0 26138.86206897 0.149710134398301 1.5483 0.8005 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L07 mock treatment 1389830.0 218000.0 1.07 1025190.0 27000.0 0.16 1298450.0 269758.86206897 1.54504183804623 1.6002 0.8493 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L08 mock treatment 1317320.0 146000.0 0.71 1103040.0 105000.0 0.62 1145980.0 117288.86206897 0.671771068588879 1.1587 0.9985 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L09 mock treatment 1356640.0 185000.0 0.9 1002150.0 3910.0 0.02 1123290.0 94598.86206897 0.5418142655523 0.8482 0.8046 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L10 mock treatment 1255040.0 83400.0 0.41 1006960.0 8720.0 0.05 1058080.0 29388.86206897 0.168324484767137 0.3625 0.8162 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L11 mock treatment 1570010.0 398000.0 1.95 987680.0 -10600.0 -0.06 1247590.0 218898.86206897 1.253741573505 1.8115 0.7821 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L12 mock treatment 1416800.0 245000.0 1.2 1021540.0 23300.0 0.14 949160.0 -79531.13793103 -0.455513989747814 0.5087 0.3946 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L13 mock treatment 1508960.0 337000.0 1.65 1165990.0 168000.0 1.0 1347330.0 318638.86206897 1.82500166759352 2.5812 0.9727 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L14 mock treatment 1180230.0 8640.0 0.04 1025500.0 27300.0 0.16 1133840.0 105148.86206897 0.602239310595751 0.4657 0.7449 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L15 mock treatment 1173440.0 1850.0 0.01 1263230.0 265000.0 1.58 1055620.0 26928.86206897 0.154234853411033 1.004 0.6341 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L16 mock treatment 1133950.0 -37600.0 -0.18 1003240.0 5000.0 0.03 1013840.0 -14851.13793103 -0.0850597799458767 -0.1381 -0.6744 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L17 mock treatment 1563130.0 392000.0 1.91 994920.0 -3320.0 -0.02 1073730.0 45038.86206897 0.257959741158607 1.242 0.6434 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L18 mock treatment 1565760.0 394000.0 1.93 1233980.0 236000.0 1.4 1351770.0 323078.86206897 1.85043173394356 2.9896 0.9911 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L19 mock treatment 1413170.0 242000.0 1.18 942980.0 -55300.0 -0.33 1246740.0 218048.86206897 1.248873204947 1.2128 0.6932 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L20 mock treatment 1126200.0 -45400.0 -0.22 1038080.0 39800.0 0.24 996270.0 -32421.13793103 -0.185691821786013 -0.0985 -0.2634 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L21 mock treatment 1343130.0 172000.0 0.84 952230.0 -46000.0 -0.27 1145800.0 117108.86206897 0.670740119953067 0.7132 0.6438 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L22 mock treatment 1020750.0 -151000.0 -0.74 930350.0 -67900.0 -0.4 975870.0 -52821.13793103 -0.30253266717809 -0.8333 -0.933 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L23 mock treatment 1101730.0 -69900.0 -0.34 1020850.0 22600.0 0.13 996400.0 -32291.13793103 -0.18494724777126 -0.2262 -0.5506 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 L24 mock treatment 1338560.0 167000.0 0.82 860180.0 -138000.0 -0.82 1161610.0 132918.86206897 0.761291775131926 0.4365 0.3151 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M01 mock treatment 1117340.0 -54300.0 -0.27 1152110.0 154000.0 0.92 1095920.0 67228.86206897 0.385052797984597 0.5975 0.5816 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M02 mock treatment 1222170.0 50600.0 0.25 881690.0 -117000.0 -0.69 1167550.0 138858.86206897 0.795313080113737 0.2017 0.1862 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M03 compound treatment 1056080.0 -116000.0 -0.56 1201010.0 203000.0 1.21 948350.0 -80341.13793103 -0.46015325860897 0.1046 0.0743 1598 NINDS_001021 NCC1CCC(N)C(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M04 mock treatment 1186140.0 14500.0 0.07 942490.0 -55700.0 -0.33 986760.0 -41931.13793103 -0.240160274711437 -0.289 -0.6956 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M05 compound treatment 1271210.0 99600.0 0.49 1062560.0 64300.0 0.38 1143380.0 114688.86206897 0.656879588293811 0.8811 0.9762 1599 NINDS_001022 C=CCc1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M06 mock treatment 1176530.0 4940.0 0.02 1130160.0 132000.0 0.78 982310.0 -46381.13793103 -0.265647615985689 0.3135 0.3783 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M07 compound treatment 1369210.0 198000.0 0.97 981720.0 -16500.0 -0.1 1274810.0 246118.86206897 1.40964391720953 1.3146 0.7681 592 NINDS_001023 Oc1ccc(cc1)c2coc3cc(O)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M08 mock treatment 1251550.0 80000.0 0.39 1049050.0 50800.0 0.3 1073130.0 44438.86206897 0.254523245705899 0.5469 0.9844 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M09 compound treatment 1355960.0 184000.0 0.9 960270.0 -38000.0 -0.23 1253940.0 225248.86206897 1.2901111503795 1.1346 0.7137 1600 NINDS_001024 CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M10 mock treatment 1149920.0 -21700.0 -0.11 1094980.0 96700.0 0.58 1002640.0 -26051.13793103 -0.149207695063095 0.1849 0.3062 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M11 compound treatment 1288730.0 117000.0 0.57 995570.0 -2670.0 -0.02 1051430.0 22738.86206897 0.130236660166288 0.3965 0.6752 1601 NINDS_001025 COc1c(OC)c2ccc(=O)oc2c3ccoc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M12 mock treatment 1338330.0 167000.0 0.81 1022010.0 23800.0 0.14 1227100.0 198408.86206897 1.13638525379502 1.208 0.8596 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M13 compound treatment 803630.0 -368000.0 -1.8 669690.0 -329000.0 -1.95 649060.0 -379631.13793103 -2.174334465344 -3.4213 -0.997 422 NINDS_001026 Oc1cccc2C(=O)C=CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M14 mock treatment 1477070.0 305000.0 1.49 1005860.0 7620.0 0.05 1035390.0 6698.86206896999 0.0383676817305573 0.91 0.6092 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M15 compound treatment 1084820.0 -86800.0 -0.42 734140.0 -264000.0 -1.57 820740.0 -207951.13793103 -1.19103856647578 -1.8391 -0.9122 1602 NINDS_001027 COc1ccc(cc1)c2coc3cc(O)cc(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M16 mock treatment 1462200.0 291000.0 1.42 1086720.0 88500.0 0.53 1252480.0 223788.86206897 1.28174901144457 1.8635 0.9394 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M17 compound treatment 1276730.0 105000.0 0.51 1116890.0 119000.0 0.71 1112860.0 84168.86206897 0.48207651959939 0.9823 0.9852 1603 NINDS_001028 OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M18 mock treatment 1195390.0 23800.0 0.12 998530.0 292.0 0.0 999010.0 -29681.13793103 -0.16999849255198 -0.03 -0.1458 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M19 compound treatment 1408380.0 237000.0 1.16 978630.0 -19600.0 -0.12 1200960.0 172268.86206897 0.986668601905368 1.1703 0.7674 1604 NINDS_001029 OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M20 mock treatment 1131430.0 -40200.0 -0.2 989810.0 -8430.0 -0.05 979430.0 -49261.13793103 -0.282142794158688 -0.3051 -0.8785 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M21 compound treatment 1274800.0 103000.0 0.5 929970.0 -68300.0 -0.41 1026140.0 -2551.13793103001 -0.0146116231653598 0.0483 0.0746 1605 NINDS_001030 OC(Cn1cncn1)(Cn2cncn2)c3ccc(F)cc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M22 mock treatment 1343520.0 172000.0 0.84 950900.0 -47300.0 -0.28 1013030.0 -15661.13793103 -0.0896990488070327 0.2707 0.304 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M23 mock treatment 1129800.0 -41800.0 -0.2 989690.0 -8550.0 -0.05 925780.0 -102911.13793103 -0.589422762555008 -0.4875 -0.779 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 M24 mock treatment 1193500.0 21900.0 0.11 907330.0 -90900.0 -0.54 1049760.0 21068.86206897 0.120671747822917 -0.1806 -0.3202 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N01 mock treatment 1118910.0 -52700.0 -0.26 926170.0 -72100.0 -0.43 1088130.0 59438.86206897 0.340435632023603 -0.1995 -0.3298 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N02 mock treatment 1350600.0 179000.0 0.87 995360.0 -2880.0 -0.02 1244070.0 215378.86206897 1.23358080018245 1.2073 0.7983 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N03 mock treatment 1402100.0 231000.0 1.13 951780.0 -46500.0 -0.28 1109000.0 80308.86206897 0.459968398853634 0.7563 0.6062 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N04 mock treatment 1454950.0 283000.0 1.38 986440.0 -11800.0 -0.07 1163560.0 134868.86206897 0.772460385353228 1.2048 0.7592 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N05 mock treatment 1366590.0 195000.0 0.95 1052640.0 54400.0 0.32 1162910.0 134218.86206897 0.768737515279461 1.1807 0.9324 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N06 mock treatment 1301160.0 130000.0 0.63 976420.0 -21800.0 -0.13 1092910.0 64218.86206897 0.367813045796844 0.5029 0.6764 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N07 mock treatment 1416660.0 245000.0 1.2 1105470.0 107000.0 0.64 1243880.0 215188.86206897 1.23249257662242 1.771 0.9663 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N08 mock treatment 1319370.0 148000.0 0.72 1083640.0 85400.0 0.51 1017390.0 -11301.13793103 -0.0647271818506868 0.6727 0.76 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N09 mock treatment 1332730.0 161000.0 0.79 1012120.0 13900.0 0.08 1097390.0 68698.86206897 0.393472211843732 0.7294 0.8251 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N10 mock treatment 1174400.0 2810.0 0.01 1041180.0 42900.0 0.26 1135440.0 106748.86206897 0.61140329846964 0.5083 0.767 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N11 mock treatment 1466150.0 295000.0 1.44 1104680.0 106000.0 0.63 1306240.0 277548.86206897 1.58965900400722 2.1141 0.9456 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N12 mock treatment 1478670.0 307000.0 1.5 1105230.0 107000.0 0.64 1322640.0 293948.86206897 1.68358987971458 2.2056 0.9413 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N13 mock treatment 1363000.0 191000.0 0.94 1031840.0 33600.0 0.2 1264550.0 235858.86206897 1.35087984496822 1.4352 0.8671 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N14 mock treatment 1353720.0 182000.0 0.89 1136800.0 139000.0 0.82 989840.0 -38851.13793103 -0.222519598054202 0.861 0.6983 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N15 mock treatment 1540010.0 368000.0 1.8 1003580.0 5340.0 0.03 1202010.0 173318.86206897 0.992682468947608 1.6307 0.7932 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N16 mock treatment 1305890.0 134000.0 0.66 1050620.0 52400.0 0.31 1122520.0 93828.86206897 0.537404096387991 0.8689 0.9617 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N17 mock treatment 1210040.0 38400.0 0.19 982400.0 -15800.0 -0.09 1035170.0 6478.86206896999 0.0371076333978977 0.0755 0.3538 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N18 mock treatment 1261850.0 90300.0 0.44 1021120.0 22900.0 0.14 1052650.0 23958.86206897 0.137224200920128 0.4124 0.8565 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N19 mock treatment 1178340.0 6750.0 0.03 1026400.0 28200.0 0.17 991630.0 -37061.13793103 -0.21226738662029 -0.0068 -0.0251 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N20 mock treatment 1293280.0 122000.0 0.59 1011630.0 13400.0 0.08 1078970.0 50278.86206897 0.287971801445592 0.5555 0.8348 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N21 mock treatment 1327270.0 156000.0 0.76 979470.0 -18800.0 -0.11 1015110.0 -13581.13793103 -0.0777858645709778 0.3298 0.4268 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N22 mock treatment 1162460.0 -9130.0 -0.04 1029820.0 31600.0 0.19 1029950.0 1258.86206896999 0.00721012295933688 0.0868 0.4495 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N23 mock treatment 1473060.0 301000.0 1.47 1031130.0 32900.0 0.2 1161380.0 132688.86206897 0.759974451875055 1.4021 0.8401 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 N24 mock treatment 1342520.0 171000.0 0.84 922900.0 -75300.0 -0.45 1195200.0 166508.86206897 0.95367824555937 0.7741 0.5758 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O01 mock treatment 1055560.0 -116000.0 -0.57 937760.0 -60500.0 -0.36 1061380.0 32688.86206897 0.187225209757032 -0.4269 -0.6124 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O02 mock treatment 1262610.0 91000.0 0.44 1148220.0 150000.0 0.89 1123610.0 94918.86206897 0.543647063127077 1.0855 0.9562 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O03 compound treatment 1267040.0 95400.0 0.47 1001790.0 3550.0 0.02 1268580.0 239888.86206897 1.37396163942558 1.0747 0.7406 1606 NINDS_001031 NS(=O)(=O)c1cc2c(NC(CSCC=C)NS2(=O)=O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O04 mock treatment 1135780.0 -35800.0 -0.17 1029030.0 30800.0 0.18 1078510.0 49818.86206897 0.285337154931849 0.1694 0.4441 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O05 compound treatment 257090.0 -915000.0 -4.47 223950.0 -774000.0 -4.6 250600.0 -778091.13793103 -4.45651109548748 -7.811 -0.9999 1607 NINDS_001032 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O06 mock treatment 1379520.0 208000.0 1.02 945180.0 -53100.0 -0.32 1268840.0 240148.86206897 1.37545078745508 1.1985 0.6893 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O07 compound treatment 1379470.0 208000.0 1.02 1017340.0 19100.0 0.11 1235950.0 207258.86206897 1.18707356172246 1.3373 0.8538 1594 NINDS_001033 N[C@@H](CCCNC(=N)N[N+](=O)[O-])C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O08 mock treatment 1158150.0 -13400.0 -0.07 1022840.0 24600.0 0.15 963740.0 -64951.13793103 -0.372007150247006 -0.1682 -0.4153 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O09 compound treatment 79010.0 -1090000.0 -5.34 70400.0 -928000.0 -5.52 62740.0 -965951.13793103 -5.5324778217304 -9.4617 -0.9999 3046992 NINDS_001034 CO[C@]12[C@@H]3NC3CN2C4=C([C@@H]1COC(=O)N)C(=O)C(=C(C)C4=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O10 mock treatment 1452560.0 281000.0 1.37 1059920.0 61700.0 0.37 1275710.0 247018.86206897 1.41479866038859 1.8212 0.9082 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O11 compound treatment 1369510.0 198000.0 0.97 962680.0 -35600.0 -0.21 1260200.0 231508.86206897 1.32596525293609 1.2018 0.7263 3250 NINDS_001035 CCCCCCCCCCCCCCCCCCOCC(O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O12 mock treatment 1370930.0 199000.0 0.97 1058370.0 60100.0 0.36 1187790.0 159098.86206897 0.911237526718425 1.2948 0.9377 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O13 compound treatment 836420.0 -335000.0 -1.64 699100.0 -299000.0 -1.78 684880.0 -343811.13793103 -1.96917568681733 -3.1094 -0.9971 1317 NINDS_001036 Fc1ccc(cc1)C(c2ccccc2)(c3ccccc3F)n4ccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O14 mock treatment 1259290.0 87700.0 0.43 1055910.0 57700.0 0.34 1073000.0 44308.86206897 0.253778671691146 0.5919 0.9789 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O15 compound treatment 1240880.0 69300.0 0.34 1030000.0 31800.0 0.19 1035330.0 6638.86206896999 0.0380240321852865 0.3264 0.8381 1608 NINDS_001037 NCCCC[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N2CCC[C@H]2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O16 mock treatment 1435720.0 264000.0 1.29 1015580.0 17300.0 0.1 1192580.0 163888.86206897 0.938672215415878 1.3465 0.8421 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O17 compound treatment 1198470.0 26900.0 0.13 929410.0 -68800.0 -0.41 1011850.0 -16841.13793103 -0.0964574898640253 -0.2162 -0.4907 1609 NINDS_001038 CC(=O)O[C@@H]1CC2C(C)(C)C(=O)C=C[C@]2(C)C3CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@]54[C@]13C)c6ccoc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O18 mock treatment 1192600.0 21000.0 0.1 994910.0 -3330.0 -0.02 1070150.0 41458.86206897 0.237455318290782 0.1849 0.7128 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O19 compound treatment 1036860.0 -135000.0 -0.66 888090.0 -110000.0 -0.66 922250.0 -106441.13793103 -0.609640810801774 -1.1102 -0.9994 1610 NINDS_001039 COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O20 mock treatment 1183590.0 12000.0 0.06 956520.0 -41700.0 -0.25 1082370.0 53678.86206897 0.307445275677605 0.0681 0.1705 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O21 compound treatment 1110830.0 -60800.0 -0.3 916890.0 -81300.0 -0.48 1076810.0 48118.86206897 0.275600417815843 -0.2916 -0.4621 3173349 NINDS_001040 CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O22 mock treatment 1210300.0 38700.0 0.19 920200.0 -78000.0 -0.46 992330.0 -36361.13793103 -0.208258141925463 -0.279 -0.5141 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O23 mock treatment 1342240.0 171000.0 0.83 1084020.0 85800.0 0.51 1253120.0 224428.86206897 1.28541460659413 1.518 0.94 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 O24 mock treatment 1076070.0 -95500.0 -0.47 910420.0 -87800.0 -0.52 1012000.0 -16691.13793103 -0.0955983660008483 -0.6262 -0.8858 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P01 mock treatment 1027680.0 -144000.0 -0.7 867580.0 -131000.0 -0.78 963450.0 -65241.13793103 -0.373668123049149 -1.0703 -0.962 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P02 mock treatment 1131310.0 -40300.0 -0.2 996010.0 -2230.0 -0.01 1014750.0 -13941.13793103 -0.0798477618426027 -0.1674 -0.7865 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P03 mock treatment 977650.0 -194000.0 -0.95 878780.0 -119000.0 -0.71 950240.0 -78451.13793103 -0.449328297932939 -1.2166 -0.9605 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P04 mock treatment 1128990.0 -42600.0 -0.21 911250.0 -87000.0 -0.52 1052970.0 24278.86206897 0.139056998494906 -0.3385 -0.5891 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P05 mock treatment 1312490.0 141000.0 0.69 997410.0 -828.0 0.0 1197190.0 168498.86206897 0.965075955477519 0.9518 0.8029 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P06 mock treatment 1240010.0 68400.0 0.33 1100900.0 103000.0 0.61 1105180.0 76488.86206897 0.438089377804726 0.7984 0.9708 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P07 mock treatment 1175680.0 4090.0 0.02 927360.0 -70900.0 -0.42 1086280.0 57588.86206897 0.329839771044419 -0.0414 -0.0773 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P08 mock treatment 1209770.0 38200.0 0.19 880650.0 -118000.0 -0.7 1115870.0 87178.86206897 0.499316271787142 -0.0077 -0.0088 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P09 mock treatment 1255920.0 84300.0 0.41 1079250.0 81000.0 0.48 1131910.0 103218.86206897 0.591185250222873 0.8573 0.9891 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P10 mock treatment 1288690.0 117000.0 0.57 901440.0 -96800.0 -0.58 972480.0 -56211.13793103 -0.321948866485891 -0.1879 -0.2152 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P11 mock treatment 1251120.0 79500.0 0.39 1026690.0 28500.0 0.17 1117820.0 89128.86206897 0.510484882008444 0.6167 0.9296 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P12 mock treatment 1329610.0 158000.0 0.77 1049930.0 51700.0 0.31 1161290.0 132598.86206897 0.759458977557149 1.0617 0.9431 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P13 mock treatment 1177290.0 5700.0 0.03 1129760.0 132000.0 0.78 1136020.0 107328.86206897 0.614725244073924 0.8225 0.8265 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P14 mock treatment 1275220.0 104000.0 0.51 1072280.0 74000.0 0.44 1114270.0 85578.86206897 0.490152283913254 0.8295 0.9983 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P15 mock treatment 1208640.0 37000.0 0.18 1137990.0 140000.0 0.83 1054670.0 25978.86206897 0.148793735610912 0.6702 0.7762 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P16 mock treatment 1229380.0 57800.0 0.28 1017830.0 19600.0 0.12 1158650.0 129958.86206897 0.744338397565233 0.66 0.8203 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P17 mock treatment 1141410.0 -30200.0 -0.15 1092720.0 94500.0 0.56 1087100.0 58408.86206897 0.334536314829787 0.4324 0.645 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P18 mock treatment 1202560.0 31000.0 0.15 948210.0 -50000.0 -0.3 1122480.0 93788.86206897 0.537174996691144 0.2257 0.3569 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P19 mock treatment 1263520.0 91900.0 0.45 1064980.0 66700.0 0.4 1082340.0 53648.86206897 0.307273450904969 0.6659 0.9886 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P20 mock treatment 1250510.0 78900.0 0.39 908390.0 -89800.0 -0.53 1089190.0 60498.86206897 0.346506773990054 0.1142 0.1534 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P21 mock treatment 1274740.0 103000.0 0.5 1081460.0 83200.0 0.49 1156680.0 127988.86206897 0.733055237495508 0.9999 0.9823 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P22 mock treatment 1201760.0 30200.0 0.15 908280.0 -90000.0 -0.53 1002640.0 -26051.13793103 -0.149207695063095 -0.3099 -0.5393 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P23 mock treatment 1171210.0 -384.0 0.0 1071200.0 73000.0 0.43 1099120.0 70428.86206897 0.403380773732374 0.4823 0.8141 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.503 P24 mock treatment 1041720.0 -130000.0 -0.63 905240.0 -93000.0 -0.55 953290.0 -75401.13793103 -0.43185944604834 -0.935 -0.9883 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A01 compound treatment 910240.0 -44000.0 -0.21 839000.0 -112000.0 -0.67 934510.0 -105633.4375 -0.605014712704466 -0.8577 -0.9274 2069431 Maybridge1_000177 OCCN1CCN(CC1)c2ncc(Cl)cc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A02 compound treatment 866250.0 -88000.0 -0.43 835550.0 -115000.0 -0.69 977130.0 -63013.4375 -0.360908985713764 -0.8527 -0.9619 1539016 Maybridge1_000178 CCOC(=O)C1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A03 compound treatment 689960.0 -264000.0 -1.29 724320.0 -227000.0 -1.35 856370.0 -183773.4375 -1.05256097049549 -2.1312 -0.9946 2069432 Maybridge1_000179 c1csc(c1)c2cc3ccccc3[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A04 compound treatment 920510.0 -33700.0 -0.16 970820.0 19900.0 0.12 1060870.0 20726.5625 0.118711229635868 0.0417 0.1775 1705599 Maybridge1_000180 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A05 compound treatment 775040.0 -179000.0 -0.88 673160.0 -278000.0 -1.65 856800.0 -183343.4375 -1.05009814875438 -2.0654 -0.9633 2069433 Maybridge1_000181 [O-][N+](=O)c1cccnc1N2CCCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A06 compound treatment 940440.0 -13800.0 -0.07 945360.0 -5560.0 -0.03 1051590.0 11446.5625 0.0655600999673158 -0.0202 -0.2023 1502090 Maybridge1_000182 CCc1cccc(C)c1NC(=O)N2CCN(CC2)C(=O)OC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A07 compound treatment 959540.0 5300.0 0.03 919460.0 -31500.0 -0.19 1136050.0 95906.5625 0.549304109860198 0.2241 0.3858 2069434 Maybridge1_000183 CC(C)(C)OC(=O)NCCNC(=O)Nc1cccc(Cl)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A08 compound treatment 725610.0 -229000.0 -1.12 717990.0 -233000.0 -1.39 823960.0 -216183.4375 -1.23818899986594 -2.1595 -0.9962 2069435 Maybridge1_000184 CC1CCCC(C)N1C(=S)Nc2ccc(C)cc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A09 compound treatment 889120.0 -65100.0 -0.32 963480.0 12600.0 0.07 1088560.0 48416.5625 0.277305494778349 0.0195 0.0456 2069436 Maybridge1_000185 CC(=O)Nc1cc(ccc1n2cc(C)c(n2)C(F)(F)F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A10 compound treatment 889120.0 -65100.0 -0.32 1011600.0 60700.0 0.36 954100.0 -86043.4375 -0.492813136173545 -0.2599 -0.3774 1564219 Maybridge1_000186 Cc1ccc(cc1)c2csc3ncnc(N4CCc5ccccc5C4)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A11 compound treatment 881970.0 -72300.0 -0.35 882910.0 -68000.0 -0.4 915530.0 -124613.4375 -0.713722518858467 -0.8494 -0.9511 2069437 Maybridge1_000187 [O-][N+](=O)c1ccc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A12 compound treatment 712130.0 -242000.0 -1.18 824970.0 -126000.0 -0.75 916510.0 -123633.4375 -0.70810957628571 -1.5242 -0.9715 1073786 Maybridge1_000188 CCOC(=O)c1c(N)sc2CN(C)CCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A13 compound treatment 807840.0 -146000.0 -0.72 891790.0 -59100.0 -0.35 829440.0 -210703.4375 -1.20680234139787 -1.3127 -0.9077 2069438 Maybridge1_000189 CC(C)(C)c1ccc(cc1)C(=O)NCCNc2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A14 compound treatment 843170.0 -111000.0 -0.54 820420.0 -131000.0 -0.78 991870.0 -48273.4375 -0.276485747425568 -0.921 -0.9336 2069439 Maybridge1_000190 CC(C)(C)OC(=O)NCCCNC(=S)Nc1ccc2OCCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A15 compound treatment 977930.0 23700.0 0.12 894240.0 -56700.0 -0.34 1017980.0 -22163.4375 -0.126940920308552 -0.2011 -0.5315 1122662 Maybridge1_000191 Clc1ccc(cc1)S(=O)(=O)N2CCCN(Cc3ccc(Cl)cc3Cl)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A16 compound treatment 194400.0 -760000.0 -3.71 100720.0 -850000.0 -5.06 243360.0 -796783.4375 -4.56357109960318 -7.6971 -0.9923 2069440 Maybridge1_000192 CCCCCc1ccc(NC(=O)NNc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A17 compound treatment 910400.0 -43800.0 -0.21 908350.0 -42600.0 -0.25 957410.0 -82733.4375 -0.473855136259438 -0.5434 -0.9396 2069441 Maybridge1_000193 CC(=O)c1ccc(OCC(O)CN2CCCN(CC2)C(=O)c3cccs3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A18 compound treatment 808530.0 -146000.0 -0.71 862620.0 -88300.0 -0.53 870430.0 -169713.4375 -0.972032427053695 -1.2754 -0.9704 1083184 Maybridge1_000194 COc1ccccc1NC(=S)NCc2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A19 compound treatment 932480.0 -21800.0 -0.11 819940.0 -131000.0 -0.78 924610.0 -115533.4375 -0.66171688767415 -0.8931 -0.8692 1522108 Maybridge1_000195 COc1ccccc1C2CCN(CC2)C(=S)Nc3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A20 compound treatment 803140.0 -151000.0 -0.74 837670.0 -113000.0 -0.67 937760.0 -102383.4375 -0.58640036233563 -1.1536 -0.9957 1083188 Maybridge1_000196 CCOC(=O)c1cc(C)nc2ccc(Br)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A21 compound treatment 34280.0 -920000.0 -4.49 36100.0 -915000.0 -5.44 26250.0 -1013893.4375 -5.80706697916562 -9.0886 -0.9945 1170678 Maybridge1_000197 COc1ccc(OCC(O)CNC2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A22 compound treatment 648610.0 -306000.0 -1.49 629120.0 -322000.0 -1.91 732000.0 -308143.4375 -1.76488920291767 -2.9859 -0.9949 1914814 Maybridge1_000198 COc1ccc(/N=C/c2ccccc2O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A23 mock treatment 907000.0 -47200.0 -0.23 911940.0 -39000.0 -0.23 945060.0 -95083.4375 -0.544589667661014 -0.5815 -0.9154 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 A24 mock treatment 904560.0 -49700.0 -0.24 865170.0 -85800.0 -0.51 951520.0 -88623.4375 -0.50759006662019 -0.7276 -0.9582 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B01 compound treatment 951000.0 -3240.0 -0.02 1030240.0 79300.0 0.47 1137020.0 96876.5625 0.554859777508743 0.5835 0.8011 1118509 Maybridge1_000199 Clc1c(sc2ccccc12)C(=O)N(CCC#N)Cc3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B02 compound treatment 973760.0 19500.0 0.1 965000.0 14100.0 0.08 1096090.0 55946.5625 0.320433512709836 0.2884 0.8368 2069442 Maybridge1_000200 Clc1c(sc2ccccc12)C(=O)NNC(=S)Nc3cc(Cl)ccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B03 compound treatment 896380.0 -57900.0 -0.28 915460.0 -35500.0 -0.21 995840.0 -44303.4375 -0.253747602513482 -0.4315 -0.9931 2069443 Maybridge1_000201 O=C(N/N=C/c1cccs1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B04 compound treatment 676420.0 -278000.0 -1.36 623740.0 -327000.0 -1.95 727360.0 -312783.4375 -1.79146476775195 -2.9413 -0.9894 2069444 Maybridge1_000202 COc1ccc(cc1)C(=O)NNC(=S)Nc2ccc(Cl)cc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B05 compound treatment 907520.0 -46700.0 -0.23 911010.0 -39900.0 -0.24 1000640.0 -39503.4375 -0.226255638891817 -0.3994 -0.9998 2069445 Maybridge1_000203 COc1cc(cc(OC)c1OC)C2SCc3cc(C)c(C)cc3CS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B06 compound treatment 978320.0 24100.0 0.12 953070.0 2150.0 0.01 1024850.0 -15293.4375 -0.0875930473750436 0.0247 0.168 2069446 Maybridge1_000204 CC(=O)CS(=O)(=O)c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B07 compound treatment 975060.0 20800.0 0.1 933280.0 -17600.0 -0.1 984010.0 -56133.4375 -0.321503837856044 -0.1875 -0.5308 2069447 Maybridge1_000205 Cc1cccc(Cl)c1/N=C/2\SC(=C)C3(CCCCC3)N2C(=O)c4sc5ccccc5c4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B08 compound treatment 923940.0 -30300.0 -0.15 930450.0 -20500.0 -0.12 1028800.0 -11343.4375 -0.0649694523113816 -0.1933 -0.955 2069448 Maybridge1_000206 CC(C)CC(C)(SCC(=O)O)SCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B09 compound treatment 835380.0 -119000.0 -0.58 898780.0 -52100.0 -0.31 960110.0 -80033.4375 -0.458390906722252 -0.7789 -0.971 1559306 Maybridge1_000207 COc1ccc(NC(=S)Nc2c(C)cccc2C)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B10 compound treatment 611040.0 -343000.0 -1.68 613010.0 -338000.0 -2.01 661930.0 -378213.4375 -2.16621459686977 -3.3789 -0.9946 2069449 Maybridge1_000208 Cc1cccc2CCCN(C(=S)Nc3cccc(Cl)c3)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B11 compound treatment 849870.0 -104000.0 -0.51 934080.0 -16800.0 -0.1 1012230.0 -27913.4375 -0.159874001730338 -0.4445 -0.8176 1049127 Maybridge1_000209 CC(=O)Nc1ccc(C)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B12 compound treatment 905300.0 -48900.0 -0.24 858250.0 -92700.0 -0.55 1109150.0 69006.5625 0.39523456373045 -0.228 -0.3171 2069450 Maybridge1_000210 Fc1ccc(NC(=O)c2ccccc2NC(=S)Nc3cccc(c3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B13 compound treatment 851120.0 -103000.0 -0.5 828320.0 -123000.0 -0.73 1103450.0 63306.5625 0.362587856929723 -0.5025 -0.5248 2069451 Maybridge1_000211 COc1ccc(NC(=O)/C=N/O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B14 compound treatment 891140.0 -63100.0 -0.31 900130.0 -50800.0 -0.3 947040.0 -93103.4375 -0.533249232667077 -0.6602 -0.9624 1083091 Maybridge1_000212 CC(=O)c1cc2cc(Br)ccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B15 compound treatment 852900.0 -101000.0 -0.5 936970.0 -14000.0 -0.08 936860.0 -103283.4375 -0.591555105514692 -0.6753 -0.8704 2069452 Maybridge1_000213 [O-][N+](=O)c1ccc(SCC(=O)Nc2ccc(F)cc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B16 compound treatment 838720.0 -116000.0 -0.56 866630.0 -84300.0 -0.5 974140.0 -66003.4375 -0.378034188053093 -0.8335 -0.9873 2069453 Maybridge1_000214 CN(C)c1ccc(/C=N/CCC\N=C\c2ccc(cc2)N(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B17 compound treatment 796440.0 -158000.0 -0.77 799240.0 -152000.0 -0.9 869350.0 -170793.4375 -0.97821811886857 -1.5307 -0.9953 1921422 Maybridge1_000215 COc1ccc(/C=N/Cc2ccccc2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B18 compound treatment 899620.0 -54600.0 -0.27 885600.0 -65300.0 -0.39 1026580.0 -13563.4375 -0.0776844854864018 -0.4232 -0.886 1017542 Maybridge1_000216 Cc1cc(O)c2ccccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B19 compound treatment 851710.0 -103000.0 -0.5 939590.0 -11300.0 -0.07 961520.0 -78623.4375 -0.450315142408388 -0.5881 -0.8688 2069454 Maybridge1_000217 COc1cc(/N=C/c2ccc3OCOc3c2)c(OC)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B20 compound treatment 844230.0 -110000.0 -0.54 815060.0 -136000.0 -0.81 929710.0 -110433.4375 -0.632506676326131 -1.1419 -0.9859 2069455 Maybridge1_000218 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2ccccc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B21 compound treatment 836270.0 -118000.0 -0.58 838400.0 -113000.0 -0.67 905600.0 -134543.4375 -0.770596518600786 -1.164 -0.9931 1721646 Maybridge1_000219 Fc1ccc(cc1)N2C(SCC2=O)c3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B22 compound treatment 816030.0 -138000.0 -0.68 832960.0 -118000.0 -0.7 915680.0 -124463.4375 -0.71286339499529 -1.2064 -0.9997 2069456 Maybridge1_000220 COCCCNC(=S)Nc1cccc(Cl)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B23 mock treatment 919540.0 -34700.0 -0.17 1010980.0 60100.0 0.36 1028440.0 -11703.4375 -0.0670313495830065 0.0696 0.1736 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 B24 mock treatment 893140.0 -61100.0 -0.3 824640.0 -126000.0 -0.75 1014140.0 -26003.4375 -0.148934491205884 -0.6919 -0.842 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C01 compound treatment 970480.0 16200.0 0.08 912800.0 -38100.0 -0.23 963260.0 -76883.4375 -0.440349305595534 -0.3393 -0.6764 2069457 Maybridge1_000221 OCCN1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C02 compound treatment 828710.0 -126000.0 -0.61 829020.0 -122000.0 -0.72 911680.0 -128463.4375 -0.73577336468001 -1.1974 -0.9968 2069458 Maybridge1_000222 C1CC1Nc2ncnc3scc(c4ccccc4)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C03 compound treatment 726240.0 -228000.0 -1.11 772980.0 -178000.0 -1.06 903410.0 -136733.4375 -0.783139727003171 -1.7062 -0.9894 2069459 Maybridge1_000223 FC(F)(F)c1ccnc(n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C04 compound treatment 791870.0 -162000.0 -0.79 844240.0 -107000.0 -0.63 833840.0 -206303.4375 -1.18160137474468 -1.5065 -0.9668 2069460 Maybridge1_000224 FC(F)(F)c1ccnc(n1)N2CCC(CC2)NC(=S)NC3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C05 compound treatment 711680.0 -243000.0 -1.19 717600.0 -233000.0 -1.39 759400.0 -280743.4375 -1.60795591057734 -2.4136 -0.9924 2069461 Maybridge1_000225 CC(C)(C)OC(=O)NCCNc1ccc(cc1N)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C06 compound treatment 899700.0 -54500.0 -0.27 1076340.0 125000.0 0.75 1047390.0 7246.5625 0.0415046317983589 0.3007 0.3792 2069462 Maybridge1_000226 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)Nc2ccc(OC(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C07 compound treatment 1051720.0 97500.0 0.48 1074740.0 124000.0 0.74 1098090.0 57946.5625 0.331888497552197 0.8917 0.951 2069463 Maybridge1_000227 Cc1nc(ccc1C(=O)Nc2ccccc2F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C08 compound treatment 917230.0 -37000.0 -0.18 1030000.0 79100.0 0.47 1046620.0 6476.5625 0.0370944626340501 0.1885 0.3732 1241428 Maybridge1_000228 Clc1ccc(cc1Cl)C(=O)N2CCN(CC2)c3cccc4scc(c5ccccc5)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C09 compound treatment 959430.0 5190.0 0.03 941790.0 -9130.0 -0.05 998880.0 -41263.4375 -0.236336025553094 -0.1532 -0.6282 2069464 Maybridge1_000229 FC(F)(F)c1cnc(N2CCCN(CC2)C(=O)Nc3ccc(Cl)cc3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C10 compound treatment 707840.0 -246000.0 -1.2 711790.0 -239000.0 -1.42 687090.0 -353053.4375 -2.02211088755288 -2.6835 -0.976 2069465 Maybridge1_000230 Cc1ccc(cc1)c2csc3ncnc(NCc4ccco4)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C11 compound treatment 976960.0 22700.0 0.11 878420.0 -72500.0 -0.43 1042880.0 2736.5625 0.015673640978836 -0.1758 -0.3946 2069466 Maybridge1_000231 [O-][N+](=O)c1ccc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(F)cc3Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C12 compound treatment 888690.0 -65500.0 -0.32 1063880.0 113000.0 0.67 1061920.0 21776.5625 0.124725096678108 0.2749 0.3644 2069467 Maybridge1_000232 Fc1ccccc1c2nnn[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C13 compound treatment 767440.0 -187000.0 -0.91 675080.0 -276000.0 -1.64 690500.0 -349643.4375 -2.00258013839665 -2.6302 -0.9582 2069468 Maybridge1_000233 Cc1cc(c(C)cc1Cl)S(=O)(=O)NCCNc2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C14 compound treatment 674400.0 -280000.0 -1.37 791400.0 -160000.0 -0.95 858080.0 -182063.4375 -1.04276695845527 -1.9391 -0.9874 2069469 Maybridge1_000234 COc1ccc(NC(=S)NNC(=O)c2ccccc2[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C15 compound treatment 809010.0 -145000.0 -0.71 798850.0 -152000.0 -0.9 919390.0 -120753.4375 -0.691614398112711 -1.3311 -0.9922 2069470 Maybridge1_000235 c1csc(c1)c2ccn(n2)c3nc(ns3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C16 compound treatment 476980.0 -477000.0 -2.33 502200.0 -449000.0 -2.67 457520.0 -582623.4375 -3.33697132268322 -4.8134 -0.9889 2069471 Maybridge1_000236 CCCCCc1ccc(NC(=O)NNc2ccc(F)c(Cl)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C17 compound treatment 841370.0 -113000.0 -0.55 863300.0 -87600.0 -0.52 1022460.0 -17683.4375 -0.101281754261664 -0.6777 -0.8854 2069472 Maybridge1_000237 CCCCNC(=O)NCCNc1ccc(cn1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C18 compound treatment 904250.0 -50000.0 -0.24 808640.0 -142000.0 -0.85 889410.0 -150733.4375 -0.863324620899694 -1.1279 -0.9146 2069473 Maybridge1_000238 Cc1cccc(C)c1NC(=S)NCc2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C19 compound treatment 937620.0 -16600.0 -0.08 982460.0 31500.0 0.19 1031590.0 -8553.4375 -0.0489897484562888 0.0331 0.1576 1659799 Maybridge1_000239 CC(C)(C)OC(=O)N1CCCN(CC1)C(=S)Nc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C20 compound treatment 909310.0 -44900.0 -0.22 897700.0 -53200.0 -0.32 1034800.0 -5343.4375 -0.0306044977843002 -0.3271 -0.8467 2069474 Maybridge1_000240 NS(=O)(=O)c1ccc(/N=C/c2ccc3OCOc3c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C21 compound treatment 832960.0 -121000.0 -0.59 903540.0 -47400.0 -0.28 1004190.0 -35953.4375 -0.205923040796627 -0.6237 -0.9069 1545894 Maybridge1_000241 CCOC(=O)c1c(sc(C)c1c2ccccc2)N3C(=O)CC4(CCCC4)C3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C22 compound treatment 732050.0 -222000.0 -1.09 769710.0 -181000.0 -1.08 830110.0 -210033.4375 -1.20296492147568 -1.9434 -0.9987 1922172 Maybridge1_000242 CCOc1ccc(/N=C/c2ccccc2O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C23 mock treatment 933200.0 -21000.0 -0.1 925140.0 -25800.0 -0.15 1090040.0 49896.5625 0.285782183561696 0.0171 0.0504 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 C24 mock treatment 851410.0 -103000.0 -0.5 988740.0 37800.0 0.22 942600.0 -97543.4375 -0.558679299017118 -0.4828 -0.6156 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D01 compound treatment 978560.0 24300.0 0.12 878800.0 -72100.0 -0.43 1059680.0 19536.5625 0.111895513654664 -0.1144 -0.2493 2069475 Maybridge1_000243 Clc1cccc(NC(=S)NNC(=O)c2cccnc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D02 compound treatment 944550.0 -9690.0 -0.05 850810.0 -100000.0 -0.6 1179940.0 139796.5625 0.800683752225799 0.0912 0.0913 2069476 Maybridge1_000244 COc1cc(/C=N/c2ccc(C)c(Cl)c2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D03 compound treatment 900880.0 -53400.0 -0.26 926760.0 -24200.0 -0.14 979910.0 -60233.4375 -0.344986556782883 -0.4326 -0.9495 1915764 Maybridge1_000245 O=C(N/N=C/c1cccc2ccccc12)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D04 compound treatment 922320.0 -31900.0 -0.16 875870.0 -75100.0 -0.45 998030.0 -42113.4375 -0.241204394111097 -0.487 -0.9175 2069477 Maybridge1_000246 CCOC(=O)CSC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D05 compound treatment 749080.0 -205000.0 -1.0 812570.0 -138000.0 -0.82 891730.0 -148413.4375 -0.850036838482556 -1.5445 -0.9961 2069478 Maybridge1_000247 Cc1cc2CSC(SCc2cc1C)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D06 compound treatment 984680.0 30400.0 0.15 879100.0 -71800.0 -0.43 1144850.0 104706.5625 0.599706043166584 0.1855 0.247 2069479 Maybridge1_000248 COc1cc(/C=N/CCCC\N=C\c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D07 compound treatment 939450.0 -14800.0 -0.07 936040.0 -14900.0 -0.09 985120.0 -55023.4375 -0.315146321268534 -0.2748 -0.8196 2069480 Maybridge1_000249 Clc1c(sc2ccccc12)C(=O)N3/C(=N/c4ccccc4Cl)/SC(=C)C53CCCCC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D08 compound treatment 702400.0 -252000.0 -1.23 647720.0 -303000.0 -1.8 794980.0 -245163.4375 -1.40417173023174 -2.5621 -0.9871 1353182 Maybridge1_000250 Cc1ccc2N(CCCc2c1)C(=S)Nc3c(C)cccc3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D09 compound treatment 811810.0 -142000.0 -0.7 793840.0 -157000.0 -0.93 899010.0 -141133.4375 -0.808340693656364 -1.4078 -0.9929 1404608 Maybridge1_000251 COc1ccc(NC(=S)Nc2ccccc2Cl)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D10 compound treatment 701120.0 -253000.0 -1.24 650490.0 -300000.0 -1.79 781120.0 -259023.4375 -1.4835547751893 -2.602 -0.989 1705422 Maybridge1_000252 Clc1cccc(NC(=S)N2CCCc3ccccc23)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D11 compound treatment 783970.0 -170000.0 -0.83 748490.0 -202000.0 -1.2 886610.0 -153533.4375 -0.879361599678999 -1.683 -0.9858 2069481 Maybridge1_000253 CC(=O)Nc1ccc(C)c(/N=C/c2ccc(Cl)c(Cl)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D12 compound treatment 801940.0 -152000.0 -0.74 873540.0 -77400.0 -0.46 968530.0 -71613.4375 -0.410165420535914 -0.9321 -0.9646 1653449 Maybridge1_000254 Fc1ccc(NC(=O)c2ccccc2NC(=S)Nc3ccccc3Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D13 compound treatment 1022400.0 68200.0 0.33 935360.0 -15600.0 -0.09 936670.0 -103473.4375 -0.592643329074716 -0.2033 -0.2963 2069482 Maybridge1_000255 OC(=O)CSC(SCC(=O)O)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D14 compound treatment 966200.0 12000.0 0.06 852380.0 -98500.0 -0.59 1095720.0 55576.5625 0.318314340513999 -0.1208 -0.1805 1541673 Maybridge1_000256 CS(=O)(=O)N(Cc1ccccc1)Cc2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D15 compound treatment 388410.0 -566000.0 -2.76 395940.0 -555000.0 -3.3 445230.0 -594913.4375 -3.40736220453953 -5.4687 -0.9961 2069483 Maybridge1_000257 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D16 compound treatment 840970.0 -113000.0 -0.55 921080.0 -29800.0 -0.18 908040.0 -132103.4375 -0.756621437093106 -0.8588 -0.9002 1040327 Maybridge1_000258 CC(=O)Nc1cc2ccccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D17 compound treatment 815760.0 -138000.0 -0.68 919420.0 -31500.0 -0.19 837660.0 -202483.4375 -1.15972235369577 -1.1683 -0.8618 2069484 Maybridge1_000259 Cc1ccc(cc1Cl)n2c(C)nc3cc(Cl)ccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D18 compound treatment 831600.0 -123000.0 -0.6 874680.0 -76200.0 -0.45 961190.0 -78953.4375 -0.452205214907377 -0.8688 -0.9907 1578175 Maybridge1_000260 Cc1cc(O)c2cc(F)ccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D19 compound treatment 775530.0 -179000.0 -0.87 880520.0 -70400.0 -0.42 933530.0 -106613.4375 -0.610627655277222 -1.0984 -0.9595 2069485 Maybridge1_000261 CC(=O)Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D20 compound treatment 765850.0 -188000.0 -0.92 866170.0 -84800.0 -0.5 886030.0 -154113.4375 -0.882683545283283 -1.332 -0.9714 2069486 Maybridge1_000262 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D21 compound treatment 665600.0 -289000.0 -1.41 662760.0 -288000.0 -1.71 829630.0 -210513.4375 -1.20571411783785 -2.4997 -0.9897 2069487 Maybridge1_000263 COc1ccc(/N=C/c2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D22 compound treatment 711760.0 -242000.0 -1.18 798010.0 -153000.0 -0.91 840520.0 -199623.4375 -1.1433417253712 -1.8691 -0.9937 2069488 Maybridge1_000264 COCCCn1c(=O)c2ccccc2[nH]c1=S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D23 mock treatment 919930.0 -34300.0 -0.17 925940.0 -25000.0 -0.15 1002480.0 -37663.4375 -0.215717052836845 -0.3071 -0.9875 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 D24 mock treatment 846340.0 -108000.0 -0.53 937120.0 -13800.0 -0.08 962200.0 -77943.4375 -0.446420447561985 -0.6095 -0.8761 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E01 compound treatment 956860.0 2620.0 0.01 1054560.0 104000.0 0.62 1151570.0 111426.5625 0.638194792236915 0.7317 0.8246 1245819 Maybridge1_000265 OCCN1CCN(Cc2ccc(F)cc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E02 compound treatment 951330.0 -2910.0 -0.01 939630.0 -11300.0 -0.07 1069230.0 29086.5625 0.166593066276935 0.0492 0.2731 1738877 Maybridge1_000266 CN(C)CCNc1ncnc2scc(c3ccccc3)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E03 compound treatment 886420.0 -67800.0 -0.33 1025920.0 75000.0 0.45 1069360.0 29216.5625 0.167337640291689 0.1628 0.2806 2069489 Maybridge1_000267 CC(=O)Nc1cc(ccc1Sc2ccccc2N)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E04 compound treatment 841010.0 -113000.0 -0.55 1041290.0 90400.0 0.54 1035230.0 -4913.4375 -0.0281416760431927 -0.0254 -0.0329 1611827 Maybridge1_000268 CC(C)(C)OC(=O)NC1CCN(Cc2c(F)cccc2Cl)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E05 compound treatment 787000.0 -167000.0 -0.82 830790.0 -120000.0 -0.71 906160.0 -133983.4375 -0.767389122844925 -1.3272 -0.9985 2069490 Maybridge1_000269 FC(F)(F)c1ccnc(n1)N2CCCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E06 compound treatment 796870.0 -157000.0 -0.77 804280.0 -147000.0 -0.87 924990.0 -115153.4375 -0.659540440554102 -1.3282 -0.9937 2069491 Maybridge1_000270 FC(F)(F)c1ccc(NC(=O)N2CCCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E07 compound treatment 940160.0 -14100.0 -0.07 1205350.0 254000.0 1.51 1068820.0 28676.5625 0.164244794384251 0.9286 0.6096 2069492 Maybridge1_000271 CC(N1CCCCC1)C(=O)Nc2c(C)cccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E08 compound treatment 1128800.0 175000.0 0.85 1113830.0 163000.0 0.97 1095050.0 54906.5625 0.314476920591809 1.2333 0.9284 1434180 Maybridge1_000272 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCN(CC3)c4ncnc5scc(c6ccccc6)c45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E09 compound treatment 581280.0 -373000.0 -1.82 570400.0 -381000.0 -2.26 701240.0 -338903.4375 -1.94106686979318 -3.4792 -0.9957 2069493 Maybridge1_000273 OC(CNCCNc1nccc(n1)C(F)(F)F)Cn2ccc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E10 compound treatment 883540.0 -70700.0 -0.35 917440.0 -33500.0 -0.2 941310.0 -98833.4375 -0.56606776424044 -0.6412 -0.9261 2069494 Maybridge1_000274 Cc1onc(c1C(=O)N2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)c6c(Cl)cccc6Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E11 compound treatment 961920.0 7680.0 0.04 1019370.0 68400.0 0.41 1132160.0 92016.5625 0.527024164341807 0.5609 0.8411 1286913 Maybridge1_000275 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E12 compound treatment 1022950.0 68700.0 0.34 1070580.0 120000.0 0.71 1059200.0 19056.5625 0.109146317292497 0.6677 0.8406 1722412 Maybridge1_000276 OC(COc1ccc(Cl)c(Cl)c1)CN2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E13 compound treatment 967300.0 13100.0 0.06 811780.0 -139000.0 -0.83 1077760.0 37616.5625 0.215448576629603 -0.3165 -0.3691 2069495 Maybridge1_000277 FC(F)(F)c1ccnc(NC2CCN(Cc3ccccc3)CC2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E14 compound treatment 851320.0 -103000.0 -0.5 956070.0 5150.0 0.03 943200.0 -96943.4375 -0.55524280356441 -0.5932 -0.7912 2069496 Maybridge1_000278 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])c3cnc4ccccc4n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E15 compound treatment 672740.0 -281000.0 -1.38 617920.0 -333000.0 -1.98 745050.0 -295093.4375 -1.69014542682127 -2.9131 -0.9894 2069497 Maybridge1_000279 OC(COc1ccc(cc1)[N+](=O)[O-])CN2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E16 compound treatment 878770.0 -75500.0 -0.37 866630.0 -84300.0 -0.5 952740.0 -87403.4375 -0.50060252586635 -0.7913 -0.9908 2069498 Maybridge1_000280 CC(Oc1ccc(Cl)cc1Cl)C(=O)NC2=NCCS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E17 compound treatment 890660.0 -63600.0 -0.31 885380.0 -65500.0 -0.39 1030560.0 -9583.4375 -0.0548890656501044 -0.4361 -0.8697 2069499 Maybridge1_000281 FC(F)(F)c1ccnc(NCC=C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E18 compound treatment 903920.0 -50300.0 -0.25 927840.0 -23100.0 -0.14 1000440.0 -39703.4375 -0.227401137376053 -0.3525 -0.9739 2069500 Maybridge1_000282 CC(C)c1ccc(/C=C/2\CCC/C(=C\c3ccc(cc3)C(C)C)/C2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E19 compound treatment 796100.0 -158000.0 -0.77 952200.0 1280.0 0.01 962400.0 -77743.4375 -0.445274949077749 -0.6988 -0.7836 2069501 Maybridge1_000283 FC(F)(F)c1cnc(NCCCNC(=S)Nc2cccnc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E20 compound treatment 932510.0 -21700.0 -0.11 955630.0 4710.0 0.03 1006350.0 -33793.4375 -0.193551657166878 -0.1569 -0.705 2069502 Maybridge1_000284 Cc1cc(C)nc(NS(=O)(=O)c2ccc(/N=C/c3ccccc3O)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E21 compound treatment 882030.0 -72200.0 -0.35 872960.0 -78000.0 -0.46 962010.0 -78133.4375 -0.447508671122009 -0.7297 -0.9933 1322088 Maybridge1_000285 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCCN(CC3)c4nc5ccc(Cl)cc5s4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E22 compound treatment 832000.0 -122000.0 -0.6 762340.0 -189000.0 -1.12 842400.0 -197743.4375 -1.13257403961938 -1.6462 -0.9672 2069503 Maybridge1_000286 Cc1ccc(/N=C/c2ccccc2O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E23 mock treatment 941930.0 -12300.0 -0.06 927430.0 -23500.0 -0.14 1044270.0 4126.5625 0.0236348554442766 -0.1017 -0.6609 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 E24 mock treatment 989810.0 35600.0 0.17 932720.0 -18200.0 -0.11 1057760.0 17616.5625 0.100898728205998 0.0961 0.421 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F01 compound treatment 809680.0 -145000.0 -0.71 899320.0 -51600.0 -0.31 893440.0 -146703.4375 -0.840242826442338 -1.0701 -0.9389 2069504 Maybridge1_000287 Cc1cccc(C)c1NC(=S)NNC(=O)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F02 compound treatment 1087950.0 134000.0 0.65 951610.0 687.0 0.0 1151700.0 111556.5625 0.638939366251669 0.7484 0.819 2069505 Maybridge1_000288 Fc1ccc(/N=C/c2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F03 compound treatment 907540.0 -46700.0 -0.23 910490.0 -40400.0 -0.24 1195740.0 155596.5625 0.891178132480446 0.244 0.2566 2069506 Maybridge1_000289 Clc1ccccc1/C=N/NC(=O)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F04 compound treatment 663320.0 -291000.0 -1.42 763890.0 -187000.0 -1.11 696180.0 -343963.4375 -1.97004798144435 -2.6002 -0.9732 2069507 Maybridge1_000290 COC(=O)c1cccc(/N=C/c2cc(Cl)cc(Cl)c2O)c1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F05 compound treatment 928260.0 -26000.0 -0.13 952060.0 1140.0 0.01 1272480.0 232336.5625 1.33070590088182 0.6989 0.5228 2069508 Maybridge1_000291 Cc1cc2CSC(C)(SCc2cc1C)c3ccc(cc3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F06 compound treatment 723000.0 -231000.0 -1.13 727680.0 -223000.0 -1.33 677150.0 -362993.4375 -2.07904216221941 -2.6191 -0.9653 1461154 Maybridge1_000292 CC(N(Cc1ccccc1)C(=S)Nc2ccc(Cl)c(Cl)c2)c3ccccc3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F07 compound treatment 828800.0 -125000.0 -0.61 732640.0 -218000.0 -1.3 963520.0 -76623.4375 -0.438860157566027 -1.3566 -0.9038 2069509 Maybridge1_000293 Cc1cccc(Cl)c1/N=C/2\NC3(CCCCC3)C(=C)S2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F08 compound treatment 657140.0 -297000.0 -1.45 774170.0 -177000.0 -1.05 863850.0 -176293.4375 -1.00971932718506 -2.0279 -0.9858 1680637 Maybridge1_000294 Cc1cccc(C)c1NC(=S)N2CCCc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F09 compound treatment 934890.0 -19300.0 -0.09 950120.0 -803.0 0.0 1030850.0 -9293.4375 -0.0532280928479622 -0.0881 -0.811 1024118 Maybridge1_000295 CC(=O)Nc1cc(ccc1C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F10 compound treatment 760340.0 -194000.0 -0.95 735690.0 -215000.0 -1.28 828160.0 -211983.4375 -1.21413353169698 -1.9869 -0.9922 1253012 Maybridge1_000296 Cc1ccc(NC(=S)N2CCCc3cccc(C)c23)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F11 compound treatment 907150.0 -47100.0 -0.23 943840.0 -7080.0 -0.04 1220280.0 180136.5625 1.03173079649621 0.4385 0.4145 1011159 Maybridge1_000297 CC(=O)Nc1ccc(C)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F12 compound treatment 737000.0 -217000.0 -1.06 788900.0 -162000.0 -0.96 821210.0 -218933.4375 -1.25393960402419 -1.893 -0.994 1486966 Maybridge1_000298 Cc1ccc(NC(=S)Nc2ccccc2C(=O)Nc3ccc(F)cc3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F13 compound treatment 1215540.0 261000.0 1.28 934680.0 -16200.0 -0.1 1011840.0 -28303.4375 -0.162107723774598 0.5877 0.4554 2069510 Maybridge1_000299 COc1cc(cc(OC)c1OC)C(SCC(=O)O)SCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F14 compound treatment 910660.0 -43600.0 -0.21 884700.0 -66200.0 -0.39 913880.0 -126263.4375 -0.723172881353414 -0.7678 -0.9027 2069511 Maybridge1_000300 CC(C)N(Cc1ccc(cc1)N(C)C)C(=S)Nc2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F15 compound treatment 393140.0 -561000.0 -2.74 417410.0 -534000.0 -3.17 457280.0 -582863.4375 -3.33834592086431 -5.3418 -0.9967 2069512 Maybridge1_000301 Oc1ccc(Br)cc1/C=N/c2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F16 compound treatment 848320.0 -106000.0 -0.52 799480.0 -151000.0 -0.9 987930.0 -52213.4375 -0.299052067565018 -0.9914 -0.9172 1177391 Maybridge1_000302 Oc1ccc(CCc2nnc(S)n2c3ccc(F)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F17 compound treatment 791110.0 -163000.0 -0.8 814760.0 -136000.0 -0.81 884960.0 -155183.4375 -0.888811962173946 -1.4408 -0.9988 2069513 Maybridge1_000303 Cc1nc2cc(Cl)ccc2c(=O)n1c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F18 compound treatment 1075530.0 121000.0 0.59 916640.0 -34300.0 -0.2 963570.0 -76573.4375 -0.438573782944968 -0.0288 -0.0376 1393574 Maybridge1_000304 Cc1cc(O)c2c(Cl)ccc(C)c2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F19 compound treatment 687420.0 -267000.0 -1.3 684710.0 -266000.0 -1.58 807550.0 -232593.4375 -1.33217715049751 -2.4358 -0.996 1113094 Maybridge1_000305 COC(=O)c1ccccc1NC(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F20 compound treatment 687460.0 -267000.0 -1.3 691040.0 -260000.0 -1.55 772960.0 -267183.4375 -1.53029111334613 -2.5283 -0.9971 2069514 Maybridge1_000306 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F21 compound treatment 865170.0 -89100.0 -0.44 857300.0 -93600.0 -0.56 979620.0 -60523.4375 -0.346647529585025 -0.7728 -0.9819 2069515 Maybridge1_000307 C(/N=C/c1ccc2OCOc2c1)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F22 compound treatment 861530.0 -92700.0 -0.45 868820.0 -82100.0 -0.49 1064530.0 24386.5625 0.139673851897388 -0.4628 -0.68 2069516 Maybridge1_000308 COCCCNC(=S)Nc1ccc(C)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F23 mock treatment 936000.0 -18200.0 -0.09 878730.0 -72200.0 -0.43 981070.0 -59073.4375 -0.338342665574314 -0.4946 -0.8931 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 F24 mock treatment 835950.0 -118000.0 -0.58 901920.0 -49000.0 -0.29 991520.0 -48623.4375 -0.278490369772981 -0.6627 -0.9405 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G01 compound treatment 1016100.0 61900.0 0.3 993240.0 42300.0 0.25 1142080.0 101936.5625 0.583840889159915 0.6569 0.9331 2069517 Maybridge1_000309 On1nnc2ccc(cc12)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G02 compound treatment 1068130.0 114000.0 0.56 1068410.0 117000.0 0.7 1199200.0 159056.5625 0.91099525625773 1.2506 0.9802 2069518 Maybridge1_000310 CCOC(=O)c1cc(C(=S)N)c(C)nc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G03 compound treatment 919960.0 -34300.0 -0.17 848180.0 -103000.0 -0.61 1019610.0 -20533.4375 -0.117605107662028 -0.5173 -0.8029 1521295 Maybridge1_000311 CCOC(=O)C1CCN(CC1)c2nc3ccc(Cl)cc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G04 compound treatment 917920.0 -36300.0 -0.18 919120.0 -31800.0 -0.19 1028580.0 -11563.4375 -0.0662295006440413 -0.2499 -0.9336 2069519 Maybridge1_000312 CC(C)(C)OC(=O)NC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G05 compound treatment 443840.0 -510000.0 -2.49 798180.0 -153000.0 -0.91 709560.0 -330583.4375 -1.89341413284896 -3.0573 -0.9378 2069520 Maybridge1_000313 Fc1cccc(Cl)c1CN2CCN(CC2)c3nccc(n3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G06 compound treatment 708870.0 -245000.0 -1.2 659040.0 -292000.0 -1.74 32570.0 -1007573.4375 -5.77086922706376 -5.0261 -0.818 2069521 Maybridge1_000314 COc1ccccc1NC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G07 compound treatment 888970.0 -65300.0 -0.32 851570.0 -99400.0 -0.59 1018780.0 -21363.4375 -0.122358926371608 -0.5959 -0.8731 1674114 Maybridge1_000315 CCc1ccccc1n2c(S)nc3ccccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G08 compound treatment 938430.0 -15800.0 -0.08 942920.0 -8000.0 -0.05 1113860.0 73716.5625 0.422211053034209 0.1717 0.3976 2069522 Maybridge1_000316 CCCCCc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)OC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G09 compound treatment 797890.0 -156000.0 -0.76 875970.0 -75000.0 -0.45 917440.0 -122703.4375 -0.702783008334012 -1.1041 -0.9774 2069523 Maybridge1_000317 OC1CCCCC1NCCNc2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G10 compound treatment 819680.0 -135000.0 -0.66 892840.0 -58100.0 -0.35 925340.0 -114803.4375 -0.657535818206688 -0.9586 -0.9664 2069524 Maybridge1_000318 FC(F)(F)c1ccnc(n1)N2CCCN(CC2)c3ncnc4scc(c5ccccc5)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G11 compound treatment 877850.0 -76400.0 -0.37 873930.0 -77000.0 -0.46 975950.0 -64193.4375 -0.367667426770757 -0.6921 -0.9947 2069525 Maybridge1_000319 CC(C)(C)c1ccc(NC(=O)N2CCCN(CC2)c3ccc(cn3)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G12 compound treatment 958320.0 4080.0 0.02 1154790.0 204000.0 1.21 1036820.0 -3323.4375 -0.0190349630935162 0.7005 0.5776 2069526 Maybridge1_000320 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)NCCCN2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G13 compound treatment 1169460.0 215000.0 1.05 1014920.0 64000.0 0.38 1269840.0 229696.5625 1.3155853208899 1.5864 0.9188 1664341 Maybridge1_000321 S=C(NCC1CC1)Nc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G14 compound treatment 955290.0 1050.0 0.01 1005130.0 54200.0 0.32 982740.0 -57403.4375 -0.328777753230943 -7.0E-4 -0.0016 1019841 Maybridge1_000322 Cc1ccccc1C(=O)c2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G15 compound treatment 350520.0 -604000.0 -2.95 325290.0 -626000.0 -3.72 379940.0 -660203.4375 -3.78131018471839 -6.0341 -0.9941 2069527 Maybridge1_000323 FC(F)(F)c1ccnc(n1)n2ccc(n2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G16 compound treatment 54520.0 -900000.0 -4.4 50170.0 -901000.0 -5.36 48610.0 -991533.4375 -5.67900024862803 -8.9092 -0.9944 1780339 Maybridge1_000324 [O-][N+](=O)c1ccc(o1)C(=O)Nc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G17 compound treatment 847140.0 -107000.0 -0.52 922190.0 -28700.0 -0.17 963920.0 -76223.4375 -0.436569160597555 -0.6528 -0.9292 2069528 Maybridge1_000325 FC(F)(F)c1ccnc(NCCN2C(=O)CC3(CCCC3)C2=O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G18 compound treatment 1051720.0 97500.0 0.48 925400.0 -25500.0 -0.15 964320.0 -75823.4375 -0.434278163629083 -0.0634 -0.0957 2069529 Maybridge1_000326 CC/1CC(C)(C)C\C1=N/Nc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G19 compound treatment 1123650.0 169000.0 0.83 919010.0 -31900.0 -0.19 1220400.0 180256.5625 1.03241809558675 0.9644 0.7214 2069530 Maybridge1_000327 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2ccc(nc2C)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G20 compound treatment 815570.0 -139000.0 -0.68 830440.0 -120000.0 -0.72 948960.0 -91183.4375 -0.522252447218411 -1.1063 -0.9915 2069531 Maybridge1_000328 C/C(=N\N=C(/C)\c1ccc(C)cc1)/c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G21 compound treatment 918400.0 -35800.0 -0.18 908860.0 -42100.0 -0.25 1019360.0 -20783.4375 -0.119036980767323 -0.3142 -0.9589 2069532 Maybridge1_000329 CC(C)(C)OC(=O)NCCNc1ccc(cc1N2C(=O)CC3(CCCC3)C2=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G22 compound treatment 692720.0 -262000.0 -1.28 650240.0 -301000.0 -1.79 749020.0 -291123.4375 -1.66740728190919 -2.7327 -0.9906 2069533 Maybridge1_000330 CC(=O)Nc1ccc(Br)cc1C(=O)C(=O)Nc2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G23 mock treatment 917880.0 -36400.0 -0.18 932250.0 -18700.0 -0.11 1019410.0 -20733.4375 -0.118750606146264 -0.2352 -0.9768 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 G24 mock treatment 1025240.0 71000.0 0.35 951970.0 1050.0 0.01 1045760.0 5616.5625 0.0321688191518351 0.2225 0.6384 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H01 compound treatment 990890.0 36700.0 0.18 945960.0 -4960.0 -0.03 1244980.0 204836.5625 1.17319985929936 0.7637 0.6433 1944160 Maybridge1_000331 O=C(NNC(=S)Nc1ccccc1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H02 compound treatment 786180.0 -168000.0 -0.82 757440.0 -193000.0 -1.15 844480.0 -195663.4375 -1.12066085538332 -1.7854 -0.9897 2069534 Maybridge1_000332 Fc1ccc(cc1)N2C(SCC2=O)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H03 compound treatment 1030400.0 76200.0 0.37 917920.0 -33000.0 -0.2 988480.0 -51663.4375 -0.295901946733369 -0.0693 -0.1347 2069535 Maybridge1_000333 CC(=O)N1N=C(OC1c2ccccc2Cl)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H04 compound treatment 1131880.0 178000.0 0.87 1034330.0 83400.0 0.5 1057890.0 17746.5625 0.101643302220751 0.8461 0.8421 2069536 Maybridge1_000334 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)SCC(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H05 compound treatment 971570.0 17300.0 0.08 1027870.0 76900.0 0.46 1099770.0 59626.5625 0.341510684819779 0.5102 0.884 2069537 Maybridge1_000335 Cc1cc2CSC(C)(SCc2cc1C)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H06 compound treatment 968970.0 14700.0 0.07 940880.0 -10000.0 -0.06 1112640.0 72496.5625 0.415223512280369 0.2468 0.5799 2069538 Maybridge1_000336 NNS(=O)(=O)c1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H07 compound treatment 962240.0 8000.0 0.04 970360.0 19400.0 0.12 1199170.0 159026.5625 0.910823431485095 0.6152 0.6694 1917064 Maybridge1_000337 S=c1nc2[nH]c3ccccc3c2n[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H08 compound treatment 829180.0 -125000.0 -0.61 756800.0 -194000.0 -1.15 949840.0 -90303.4375 -0.517212253887773 -1.3179 -0.9381 2069539 Maybridge1_000338 FC(F)(F)c1cccc(NC(=S)N2CCc3ccccc3C2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H09 compound treatment 843930.0 -110000.0 -0.54 601280.0 -350000.0 -2.08 764960.0 -275183.4375 -1.57611105271557 -2.4215 -0.9089 1048074 Maybridge1_000339 CN(C)c1ccc(cc1)C2Nc3cccc4cccc(N2)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H10 compound treatment 712400.0 -242000.0 -1.18 783170.0 -168000.0 -1.0 765380.0 -274763.4375 -1.57370550589868 -2.1667 -0.982 1205163 Maybridge1_000340 Cc1ccc(NC(=S)N2CCCc3ccccc23)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H11 compound treatment 852170.0 -102000.0 -0.5 843690.0 -107000.0 -0.64 1031120.0 -9023.4375 -0.0516816698942435 -0.6859 -0.8456 2069540 Maybridge1_000341 COc1nc(Nc2cccc(c2)C(F)(F)F)nc(OC)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H12 compound treatment 692070.0 -262000.0 -1.28 789890.0 -161000.0 -0.96 873360.0 -166783.4375 -0.955250874259637 -1.8439 -0.9898 1127694 Maybridge1_000342 Fc1ccc(NC(=O)c2ccccc2NC(=S)Nc3ccc(Cl)c(Cl)c3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H13 compound treatment 858080.0 -96200.0 -0.47 1138300.0 187000.0 1.11 1353640.0 313496.5625 1.7955491857848 1.4087 0.6508 2069541 Maybridge1_000343 OC(=O)CSC(SCC(=O)O)c1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H14 compound treatment 1092490.0 138000.0 0.68 790880.0 -160000.0 -0.95 875200.0 -164943.4375 -0.944712288204665 -0.7049 -0.4695 2069542 Maybridge1_000344 CC(C)N(Cc1ccc(cc1)N(C)C)C(=S)Nc2ccc(C)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H15 compound treatment 1211880.0 258000.0 1.26 904130.0 -46800.0 -0.28 1001330.0 -38813.4375 -0.222303669121203 0.4378 0.3346 1367412 Maybridge1_000345 CCOC(=O)c1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(F)cc3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H16 compound treatment 839770.0 -114000.0 -0.56 952680.0 1760.0 0.01 901500.0 -138643.4375 -0.794079237527625 -0.7753 -0.7982 1578868 Maybridge1_000346 Cc1c(Cl)cccc1n2c(S)nnc2CCc3ccc(O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H17 compound treatment 714980.0 -239000.0 -1.17 712400.0 -239000.0 -1.42 821410.0 -218733.4375 -1.25279410553995 -2.2171 -0.9967 1141423 Maybridge1_000347 Cc1nc2cc(Cl)ccc2c(=O)n1c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H18 compound treatment 896810.0 -57400.0 -0.28 892800.0 -58100.0 -0.35 876210.0 -163933.4375 -0.938927520859273 -0.9036 -0.8696 1562593 Maybridge1_000348 Cc1cc(O)c2cc(Cl)ccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H19 compound treatment 806340.0 -148000.0 -0.72 749060.0 -202000.0 -1.2 854880.0 -185263.4375 -1.06109493420305 -1.7229 -0.9803 1160657 Maybridge1_000349 COC(=O)c1ccccc1NC(=O)c2cc(OC)c(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H20 compound treatment 402810.0 -551000.0 -2.69 378100.0 -573000.0 -3.41 429050.0 -611093.4375 -3.50003303191423 -5.5429 -0.9937 2069543 Maybridge1_000350 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2cc(Cl)cc(Cl)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H21 compound treatment 699360.0 -255000.0 -1.25 737200.0 -214000.0 -1.27 902800.0 -137343.4375 -0.786633497380091 -1.9069 -0.9802 1285265 Maybridge1_000351 CCOC(=O)C1CCN(CC1)c2nc(OC)nc(OC)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H22 compound treatment 802520.0 -152000.0 -0.74 872640.0 -78300.0 -0.47 919810.0 -120333.4375 -0.689208851295815 -1.0946 -0.9826 2069544 Maybridge1_000352 CN(C)c1ccc(/C=N/c2ccc(cc2)N3N=C(C)CC3=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H23 mock treatment 922210.0 -32000.0 -0.16 1009030.0 58100.0 0.35 1089440.0 49296.5625 0.282345688108988 0.2722 0.5756 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 H24 mock treatment 944110.0 -10100.0 -0.05 1013280.0 62400.0 0.37 1087810.0 47666.5625 0.273009875462464 0.3431 0.7409 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I01 compound treatment 1003200.0 49000.0 0.24 844640.0 -106000.0 -0.63 959150.0 -80993.4375 -0.463889299446585 -0.4946 -0.6034 1454622 Maybridge1_000353 OCCN1CCN(CC1)c2nc3ccc(Cl)cc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I02 compound treatment 751940.0 -202000.0 -0.99 800370.0 -151000.0 -0.9 880590.0 -159553.4375 -0.913841104054504 -1.6151 -0.9991 2069545 Maybridge1_000354 NC1CCN(CC1)c2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I03 compound treatment 175520.0 -779000.0 -3.8 191550.0 -759000.0 -4.52 206210.0 -833933.4375 -4.77634744305003 -7.5614 -0.9956 1575257 Maybridge1_000355 Clc1ccc2nc(sc2c1)N3CCCNCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I04 compound treatment 1004540.0 50300.0 0.25 1067240.0 116000.0 0.69 1059920.0 19776.5625 0.113270111835747 0.6066 0.8168 1654743 Maybridge1_000356 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I05 compound treatment 710050.0 -244000.0 -1.19 632810.0 -318000.0 -1.89 746810.0 -293333.4375 -1.68006504016 -2.751 -0.9835 1266004 Maybridge1_000357 CCOC(=O)c1c(N)scc1C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I06 compound treatment 107890.0 -846000.0 -4.14 595900.0 -355000.0 -2.11 221190.0 -818953.4375 -4.69054960658075 -6.3144 -0.9568 2069546 Maybridge1_000358 FC(F)(F)c1ccc(NC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I07 compound treatment 996090.0 41900.0 0.2 1213600.0 263000.0 1.56 1185690.0 145546.5625 0.833616833647585 1.5012 0.8423 2069547 Maybridge1_000359 Cc1nc(ccc1C#N)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I08 compound treatment 948700.0 -5540.0 -0.03 982690.0 31800.0 0.19 1054790.0 14646.5625 0.0838880757150926 0.1419 0.6806 2069548 Maybridge1_000360 Cc1nc(nc(N2CCCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1Cl)c4cccnc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I09 compound treatment 957460.0 3220.0 0.02 921540.0 -29400.0 -0.17 1040660.0 516.5625 0.00295860780381591 -0.0901 -0.5134 2069549 Maybridge1_000361 CC(C)(C)OC(=O)N/N=C\c1cccc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I10 compound treatment 610760.0 -343000.0 -1.68 646290.0 -305000.0 -1.81 828420.0 -211723.4375 -1.21264438366748 -2.7149 -0.9869 2069550 Maybridge1_000362 Cc1c(sc2ncnc(O)c12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I11 compound treatment 647770.0 -306000.0 -1.5 589720.0 -361000.0 -2.15 641560.0 -398583.4375 -2.28288361748921 -3.4226 -0.9853 1256094 Maybridge1_000363 OC(CNC1CCN(Cc2ccccc2)CC1)COc3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I12 compound treatment 876590.0 -77600.0 -0.38 934150.0 -16800.0 -0.1 1081850.0 41706.5625 0.23887402063223 -0.1387 -0.302 2069551 Maybridge1_000364 FC(F)(F)c1ccnc(n1)N2CCN(CCCNC(=O)c3cccs3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I13 compound treatment 870010.0 -84200.0 -0.41 1115250.0 164000.0 0.98 1282240.0 242096.5625 1.38660622691254 1.1271 0.6457 1454379 Maybridge1_000365 S=C(NCc1ccco1)Nc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I14 compound treatment 794570.0 -160000.0 -0.78 779850.0 -171000.0 -1.02 913120.0 -127023.4375 -0.727525775593511 -1.4578 -0.989 1651773 Maybridge1_000366 COC(=O)c1ccc(CSc2ccccc2NC(=S)Nc3cccc(SC)c3)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I15 compound treatment 792960.0 -161000.0 -0.79 784100.0 -167000.0 -0.99 910170.0 -129973.4375 -0.744421878235993 -1.4575 -0.9919 2069552 Maybridge1_000367 [O-][N+](=O)c1cc(ccc1n2ccc(n2)c3cccs3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I16 compound treatment 58530.0 -896000.0 -4.38 71360.0 -880000.0 -5.23 70660.0 -969483.4375 -5.55270904074101 -8.7523 -0.9952 2069553 Maybridge1_000368 CCOC(=O)c1ccc(NC(=O)c2ccc(o2)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I17 compound treatment 838730.0 -116000.0 -0.56 855650.0 -95300.0 -0.57 867780.0 -172363.4375 -0.987210281969823 -1.2229 -0.9626 2069554 Maybridge1_000369 FC(F)(F)c1cccnc1NCCN2C(=O)CC3(CCCC3)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I18 compound treatment 642400.0 -312000.0 -1.52 702680.0 -248000.0 -1.48 714210.0 -325933.4375 -1.86678129309047 -2.8097 -0.9943 1352465 Maybridge1_000370 CC(C)c1ccc(NC2(CCCCC2)C(=O)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I19 compound treatment 676050.0 -278000.0 -1.36 670730.0 -280000.0 -1.67 758660.0 -281483.4375 -1.61219425496901 -2.6775 -0.9963 2069555 Maybridge1_000371 COc1ccc(OCC(O)CNCCNc2ncccc2C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I20 compound treatment 713210.0 -241000.0 -1.18 641150.0 -310000.0 -1.84 706240.0 -333903.4375 -1.91242940768728 -2.8476 -0.9803 2069556 Maybridge1_000372 C/C(=N\N=C(/C)\c1ccc(C)cc1C)/c2ccc(C)cc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I21 compound treatment 552640.0 -402000.0 -1.96 579930.0 -371000.0 -2.21 580390.0 -459753.4375 -2.63323432889281 -3.9268 -0.9926 1262020 Maybridge1_000373 OC(CN1CCC(CC1)NC2CCCCC2O)Cn3ccc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I22 compound treatment 961000.0 6760.0 0.03 818250.0 -133000.0 -0.79 991200.0 -48943.4375 -0.280323167347758 -0.5983 -0.714 2069557 Maybridge1_000374 COc1ccc(cc1)/C(=N/N=C/c2cc(OC)c(OC)c(OC)c2)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I23 mock treatment 996530.0 42300.0 0.21 892250.0 -58700.0 -0.35 1055650.0 15506.5625 0.0888137191973076 -0.0309 -0.0743 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 I24 mock treatment 963920.0 9680.0 0.05 914580.0 -36300.0 -0.22 1081700.0 41556.5625 0.238014896769053 0.04 0.123 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J01 compound treatment 1048370.0 94100.0 0.46 920870.0 -30100.0 -0.18 1111850.0 71706.5625 0.410698793267637 0.3995 0.6222 2069558 Maybridge1_000375 COc1cc(cc(OC)c1OC)C(=O)NNC(=O)c2sc3ccccc3c2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J02 compound treatment 1004530.0 50300.0 0.25 1014910.0 64000.0 0.38 992480.0 -47663.4375 -0.272991977048648 0.2039 0.3856 2069559 Maybridge1_000376 COc1cc(NS(=O)(=O)c2cc(ccc2C)[N+](=O)[O-])c(OC)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J03 compound treatment 1082500.0 128000.0 0.63 1192900.0 242000.0 1.44 1199260.0 159116.5625 0.911338905803001 1.7187 0.947 2069560 Maybridge1_000377 COc1ccc(/C=N/NC(=O)c2ccncc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J04 compound treatment 928040.0 -26200.0 -0.13 819170.0 -132000.0 -0.78 1066590.0 26446.5625 0.151472486285019 -0.4388 -0.5429 2069561 Maybridge1_000378 COc1ccc(cc1)c2nnc(S)n2c3cccc(OC)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J05 compound treatment 477150.0 -477000.0 -2.33 614490.0 -336000.0 -2.0 131610.0 -908533.4375 -5.20361837767007 -5.5052 -0.9111 2069562 Maybridge1_000379 COc1cc(ccc1O)C2(C)SCc3cc(C)c(C)cc3CS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J06 compound treatment 1146560.0 192000.0 0.94 981380.0 30500.0 0.18 1138360.0 98216.5625 0.562534617353125 0.9719 0.8755 2069563 Maybridge1_000380 CC(SCC(=O)O)(SCC(=O)O)c1cccc(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J07 compound treatment 1027360.0 73100.0 0.36 967600.0 16700.0 0.1 951580.0 -88563.4375 -0.507246417074919 -0.0293 -0.0467 1140994 Maybridge1_000381 Cc1onc(c1C(=O)N2CCc3ccccc3C2)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J08 compound treatment 494820.0 -459000.0 -2.24 534050.0 -417000.0 -2.48 531630.0 -508513.4375 -2.91250685934956 -4.4087 -0.9941 2069564 Maybridge1_000382 Cc1cccc2CCCN(C(=S)Nc3cccc(c3)C(F)(F)F)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J09 compound treatment 715280.0 -239000.0 -1.17 697600.0 -253000.0 -1.51 724390.0 -315753.4375 -1.80847542024286 -2.5879 -0.985 1048961 Maybridge1_000383 COc1cc(cc(OC)c1OC)C2Nc3cccc4cccc(N2)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J10 compound treatment 655140.0 -299000.0 -1.46 604660.0 -346000.0 -2.06 691680.0 -348463.4375 -1.99582169733966 -3.1848 -0.9895 2069565 Maybridge1_000384 Oc1ccc(CCC(=O)N/N=C/c2ccc(Cl)c(Cl)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J11 compound treatment 601980.0 -352000.0 -1.72 600800.0 -350000.0 -2.08 638010.0 -402133.4375 -2.3032162155844 -3.5255 -0.9931 2069566 Maybridge1_000385 Cc1ccc(Nc2nc3ccccc3s2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J12 compound treatment 851040.0 -103000.0 -0.5 964690.0 13800.0 0.08 910170.0 -129973.4375 -0.744421878235993 -0.6736 -0.7461 2069567 Maybridge1_000386 Oc1ccc(CCC(=O)NNC(=S)Nc2cccc(c2)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J13 compound treatment 875040.0 -79200.0 -0.39 1092350.0 141000.0 0.84 1072130.0 31986.5625 0.183202794298358 0.3679 0.3899 1383075 Maybridge1_000387 CC1CC(=O)Nc2ccccc2N1C(=O)c3c(C)onc3c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J14 compound treatment 845960.0 -108000.0 -0.53 988640.0 37700.0 0.22 920540.0 -119603.4375 -0.685027781828354 -0.5714 -0.6391 2069568 Maybridge1_000388 CC(C)N(Cc1ccc(cc1)N(C)C)C(=S)Nc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J15 compound treatment 963270.0 9030.0 0.04 949760.0 -1160.0 -0.01 1052830.0 12686.5625 0.0726621905695793 0.0634 0.7438 1030886 Maybridge1_000389 CC(=O)Nc1cc(Cl)ccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J16 compound treatment 881770.0 -72500.0 -0.35 801970.0 -149000.0 -0.89 917850.0 -122293.4375 -0.700434736441328 -1.1202 -0.9466 1516286 Maybridge1_000390 Cc1ccc(c(C)c1)n2c(S)nnc2CCc3ccc(O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J17 compound treatment 594040.0 -360000.0 -1.76 517660.0 -433000.0 -2.58 692060.0 -348083.4375 -1.99364525021961 -3.6546 -0.987 2069569 Maybridge1_000391 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccccc2C(=O)Nc3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J18 compound treatment 799750.0 -154000.0 -0.75 920010.0 -30900.0 -0.18 877600.0 -162543.4375 -0.930966306393833 -1.0794 -0.8902 2069570 Maybridge1_000392 Cc1ccc(NS(=O)(=O)C)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J19 compound treatment 879490.0 -74700.0 -0.37 942500.0 -8420.0 -0.05 966240.0 -73903.4375 -0.423281378180417 -0.4841 -0.8626 1040131 Maybridge1_000393 CC1CC(=O)Nc2cc(C)c(C)cc2N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J20 compound treatment 457490.0 -497000.0 -2.43 386480.0 -564000.0 -3.36 438880.0 -601263.4375 -3.44373178141402 -5.3274 -0.989 2069571 Maybridge1_000394 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2cc(Br)ccc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J21 compound treatment 784850.0 -169000.0 -0.83 687680.0 -263000.0 -1.57 899480.0 -140663.4375 -0.805648772218409 -1.8467 -0.9493 1635307 Maybridge1_000395 Clc1c(sc2ccccc12)C(=O)N3CCCc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J22 compound treatment 737880.0 -216000.0 -1.06 740390.0 -211000.0 -1.25 754720.0 -285423.4375 -1.63476057510846 -2.2769 -0.9837 2069572 Maybridge1_000396 CC(C)CCCC(C)C1CCC2C3CC=C4C[C@H](CC[C@]4(C)C3CC[C@]12C)OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J23 mock treatment 986880.0 32600.0 0.16 963470.0 12500.0 0.07 989010.0 -51133.4375 -0.292866375750143 -0.0339 -0.0993 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 J24 mock treatment 1058050.0 104000.0 0.51 886960.0 -64000.0 -0.38 1058560.0 18416.5625 0.105480722142942 0.1341 0.2087 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K01 compound treatment 1077670.0 123000.0 0.6 1093500.0 143000.0 0.85 1180880.0 140736.5625 0.806067595101708 1.3031 0.9901 2069573 Maybridge1_000397 OCCN1CCN(CC1)c2ncccc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K02 compound treatment 731060.0 -223000.0 -1.09 753250.0 -198000.0 -1.18 706740.0 -333403.4375 -1.90956566147669 -2.4107 -0.9668 1587186 Maybridge1_000398 OC(CNCc1ccc2OCOc2c1)COc3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K03 compound treatment 1000060.0 45800.0 0.22 1012430.0 61500.0 0.37 1113760.0 73616.5625 0.421638303792091 0.5839 0.9708 1185686 Maybridge1_000399 OCCN1CCN(Cc2ccccc2F)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K04 compound treatment 1170120.0 216000.0 1.05 942410.0 -8510.0 -0.05 1077550.0 37406.5625 0.214245803221155 0.7034 0.6528 1632887 Maybridge1_000400 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K05 compound treatment 1062010.0 108000.0 0.53 1082780.0 132000.0 0.78 1262690.0 222546.5625 1.27463375007846 1.4926 0.9409 2069574 Maybridge1_000401 OC1CCN(CC1)c2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K06 compound treatment 876980.0 -77300.0 -0.38 1211780.0 261000.0 1.55 1301810.0 261666.5625 1.49869325359503 1.5429 0.7046 2069575 Maybridge1_000402 CCc1cccc(C)c1NC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K07 compound treatment 954620.0 383.0 0.0 1070570.0 120000.0 0.71 1067590.0 27446.5625 0.1571999787062 0.5026 0.6898 2069576 Maybridge1_000403 Cc1nc(ccc1C(=O)NN)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K08 compound treatment 1037280.0 83000.0 0.41 884500.0 -66400.0 -0.39 1014440.0 -25703.4375 -0.14721624347953 -0.0788 -0.1347 1289970 Maybridge1_000404 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)c3ncnc4scc(c5ccccc5)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K09 compound treatment 949790.0 -4450.0 -0.02 868840.0 -82100.0 -0.49 989540.0 -50603.4375 -0.289830804766918 -0.4617 -0.8127 2069577 Maybridge1_000405 CCOC(=O)c1cc(c2nc(cs2)C(=O)NN)c(C)nc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K10 compound treatment 979140.0 24900.0 0.12 904640.0 -46300.0 -0.28 1095960.0 55816.5625 0.319688938695083 0.0959 0.2185 2069578 Maybridge1_000406 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCNc2ncc(cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K11 compound treatment 916120.0 -38100.0 -0.19 894570.0 -56400.0 -0.34 1042560.0 2416.5625 0.0138408434040584 -0.293 -0.7638 2069579 Maybridge1_000407 FC(F)(F)c1ccnc(NCCNC(=O)c2cccs2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K12 compound treatment 749880.0 -204000.0 -1.0 757360.0 -194000.0 -1.15 966650.0 -73493.4375 -0.420933106287733 -1.484 -0.9388 1651621 Maybridge1_000408 CCCc1cnc(nc1)N2CCCN(CC2)C(=O)OC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K13 compound treatment 1011040.0 56800.0 0.28 1023120.0 72200.0 0.43 1188030.0 147886.5625 0.847019165913147 0.8971 0.9068 2069580 Maybridge1_000409 FC(F)(F)c1ccnc(NCCNC(=S)Nc2cccnc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K14 compound treatment 836740.0 -117000.0 -0.57 713970.0 -237000.0 -1.41 981440.0 -58703.4375 -0.336223493378477 -1.3391 -0.8594 2069581 Maybridge1_000410 CC(=O)c1cc(Cl)cc(Cl)c1OC(=O)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K15 compound treatment 814460.0 -140000.0 -0.68 721520.0 -229000.0 -1.36 879740.0 -160403.4375 -0.918709472612507 -1.7123 -0.9615 1570851 Maybridge1_000411 CCCc1cnc(nc1)N2CCCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K16 compound treatment 634400.0 -320000.0 -1.56 619060.0 -332000.0 -1.97 661500.0 -378643.4375 -2.16867741861088 -3.2937 -0.9913 2069582 Maybridge1_000412 FC(F)(F)c1cccc(NC(=S)NCc2ccco2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K17 compound treatment 847360.0 -107000.0 -0.52 880260.0 -70700.0 -0.42 950520.0 -89623.4375 -0.51331755904137 -0.8404 -0.9955 2069583 Maybridge1_000413 Cc1nc(ccc1NC(=O)NCCNc2nccc(n2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K18 compound treatment 890630.0 -63600.0 -0.31 988960.0 38000.0 0.23 1025120.0 -15023.4375 -0.0860466244213249 -0.0985 -0.2501 2069584 Maybridge1_000414 NC(=O)C1(CCCCC1)NC2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K19 compound treatment 848960.0 -105000.0 -0.51 846500.0 -104000.0 -0.62 1243760.0 203616.5625 1.16621231854552 0.0178 0.0126 1388914 Maybridge1_000415 CCCc1cnc(nc1)N2CCCN(CC2)C(=S)Nc3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K20 compound treatment 849620.0 -105000.0 -0.51 954510.0 3590.0 0.02 944180.0 -95963.4375 -0.549629860991653 -0.6001 -0.7992 1913698 Maybridge1_000416 COc1ccc(cc1)/C(=N/N=C(\C)/c2ccc(OC)cc2)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K21 compound treatment 798350.0 -156000.0 -0.76 893130.0 -57800.0 -0.34 931140.0 -109003.4375 -0.624316362163843 -0.9986 -0.9574 1018970 Maybridge1_000417 OC(CNCc1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K22 compound treatment 807300.0 -147000.0 -0.72 770420.0 -181000.0 -1.07 892740.0 -147403.4375 -0.844252071137164 -1.5216 -0.9863 2069585 Maybridge1_000418 COc1cc(/C=N/Nc2ccccc2)ccc1OC(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K23 mock treatment 1008410.0 54200.0 0.26 895860.0 -55100.0 -0.33 1037440.0 -2703.4375 -0.0154839177923844 -0.0452 -0.1072 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 K24 mock treatment 948530.0 -5710.0 -0.03 996930.0 46000.0 0.27 1077850.0 37706.5625 0.215964050947509 0.2665 0.7623 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L01 compound treatment 1042400.0 88200.0 0.43 950440.0 -483.0 0.0 1142190.0 102046.5625 0.584470913326245 0.5845 0.805 1429726 Maybridge1_000419 CC(=O)N1N=C(OC1(C)C)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L02 compound treatment 905360.0 -48900.0 -0.24 1030990.0 80100.0 0.48 1063520.0 23376.5625 0.133889084551996 0.2143 0.3902 2069586 Maybridge1_000420 Cc1cc(C)c(NS(=O)(=O)c2cc(ccc2C)[N+](=O)[O-])c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L03 compound treatment 1146200.0 192000.0 0.94 1134750.0 184000.0 1.09 1239840.0 199696.5625 1.14376054825449 1.833 0.9966 2069587 Maybridge1_000421 COc1cc(/C=N/CC\N=C\c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L04 compound treatment 924010.0 -30200.0 -0.15 813760.0 -137000.0 -0.82 913200.0 -126943.4375 -0.727067576199817 -0.976 -0.8851 2069588 Maybridge1_000422 COc1ccc(cc1)c2nnc(S)n2c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L05 compound treatment 1087240.0 133000.0 0.65 1007550.0 56600.0 0.34 1034660.0 -5483.4375 -0.0314063467232655 0.5515 0.7528 2069589 Maybridge1_000423 CC1CCCCC21SCc3cc(C)c(C)cc3CS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L06 compound treatment 941560.0 -12700.0 -0.06 933860.0 -17100.0 -0.1 1138910.0 98766.5625 0.565684738184774 0.2323 0.4018 2069590 Maybridge1_000424 CCCC(C)(SCC(=O)O)SCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L07 compound treatment 916760.0 -37500.0 -0.18 992930.0 42000.0 0.25 986790.0 -53353.4375 -0.305581408925163 -0.1379 -0.317 1367544 Maybridge1_000425 COc1ccc(NC(=O)C)c(NC(=O)c2c(C)onc2c3ccccc3Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L08 compound treatment 533810.0 -420000.0 -2.05 603910.0 -347000.0 -2.06 528110.0 -512033.4375 -2.93266763267211 -4.0705 -0.985 2069591 Maybridge1_000426 FC(F)(F)c1cccc(NC(=S)N2CCCc3ccccc23)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L09 compound treatment 687410.0 -267000.0 -1.3 638450.0 -312000.0 -1.86 712550.0 -327593.4375 -1.87628893050963 -2.9087 -0.9877 1178859 Maybridge1_000427 C1Oc2ccc(cc2O1)C3Nc4cccc5cccc(N3)c45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L10 compound treatment 846730.0 -108000.0 -0.53 814900.0 -136000.0 -0.81 903960.0 -136183.4375 -0.779989606171522 -1.2206 -0.984 2069592 Maybridge1_000428 COc1cc(/C=N/NC(=O)CCc2ccc(O)cc2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L11 compound treatment 428480.0 -526000.0 -2.57 512320.0 -439000.0 -2.61 325000.0 -715143.4375 -4.09597861833803 -5.3537 -0.9746 1177022 Maybridge1_000429 COc1cccc(Nc2nc3ccccc3s2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L12 compound treatment 994270.0 40000.0 0.2 832910.0 -118000.0 -0.7 957810.0 -82333.4375 -0.471564139290966 -0.5645 -0.6505 2069593 Maybridge1_000430 Cc1ccccc1NC(=S)NNC(=O)CCc2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L13 compound treatment 984590.0 30400.0 0.15 1095300.0 144000.0 0.86 1181050.0 140906.5625 0.807041268813309 1.0472 0.8818 1242977 Maybridge1_000431 CC1CC(=O)Nc2ccccc2N1C(=O)c3cccc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L14 compound treatment 1067040.0 113000.0 0.55 852360.0 -98600.0 -0.59 944770.0 -95373.4375 -0.546250640463157 -0.3356 -0.3451 2069594 Maybridge1_000432 Clc1ccc(CNC(=O)c2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L15 compound treatment 859040.0 -95200.0 -0.47 835840.0 -115000.0 -0.68 991950.0 -48193.4375 -0.276027548031873 -0.823 -0.9435 2069595 Maybridge1_000433 C(/N=C/c1ccc2OCOc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L16 compound treatment 832420.0 -122000.0 -0.6 775520.0 -175000.0 -1.04 906470.0 -133673.4375 -0.765613600194359 -1.3879 -0.9745 1485674 Maybridge1_000434 Oc1ccc(CCc2nnc(S)n2c3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L17 compound treatment 896350.0 -57900.0 -0.28 839880.0 -111000.0 -0.66 946920.0 -93223.4375 -0.533936531757619 -0.8528 -0.9528 2069596 Maybridge1_000435 Cc1ccc(SCC(=O)c2cccc(c2)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L18 compound treatment 426500.0 -528000.0 -2.58 414750.0 -536000.0 -3.19 364730.0 -675413.4375 -3.86842534444454 -5.5629 -0.9868 2069597 Maybridge1_000436 Cc1ccc(/N=C/c2cc(Cl)cc(Cl)c2O)cc1NS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L19 compound treatment 863140.0 -91100.0 -0.45 1053230.0 102000.0 0.61 1072160.0 32016.5625 0.183374619070993 0.2001 0.258 2069598 Maybridge1_000437 Cc1ccc2nc(C)oc(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L20 compound treatment 848270.0 -106000.0 -0.52 813850.0 -137000.0 -0.82 1102240.0 62096.5625 0.355657591100095 -0.5642 -0.5483 2069599 Maybridge1_000438 CN(C)c1ccc(/C=N/c2cc(NS(=O)(=O)C)ccc2C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L21 compound treatment 868570.0 -85700.0 -0.42 929250.0 -21700.0 -0.13 991690.0 -48453.4375 -0.27751669606138 -0.4763 -0.9186 1294233 Maybridge1_000439 Cc1ccc2N(CCCc2c1)C(=O)c3sc4ccccc4c3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L22 compound treatment 797560.0 -157000.0 -0.77 870620.0 -80300.0 -0.48 908840.0 -131303.4375 -0.752039443156162 -1.1518 -0.9807 2069600 Maybridge1_000440 COc1cc(/C=N/c2ccc(cc2)N3N=C(C)CC3=O)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L23 mock treatment 975270.0 21000.0 0.1 903970.0 -47000.0 -0.28 1102240.0 62096.5625 0.355657591100095 0.1035 0.2231 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 L24 mock treatment 953020.0 -1220.0 -0.01 1088480.0 138000.0 0.82 992830.0 -47313.4375 -0.270987354701235 0.3124 0.3625 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M01 compound treatment 1022890.0 68700.0 0.34 922240.0 -28700.0 -0.17 1032370.0 -7773.4375 -0.0445223043677682 0.0695 0.1834 1610519 Maybridge1_000441 Cc1nc(nc(N2CCN(CCO)CC2)c1Cl)c3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M02 compound treatment 1000860.0 46600.0 0.23 995910.0 45000.0 0.27 1099390.0 59246.5625 0.339334237699731 0.4819 0.9865 2069601 Maybridge1_000442 COc1ccccc1NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M03 compound treatment 832400.0 -122000.0 -0.6 750460.0 -200000.0 -1.19 885320.0 -154823.4375 -0.886750064902321 -1.5439 -0.9646 1254354 Maybridge1_000443 C1CNCCN(C1)c2nc(ns2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M04 compound treatment 918120.0 -36100.0 -0.18 969920.0 19000.0 0.11 1097070.0 56926.5625 0.326046455282593 0.1516 0.3911 1391909 Maybridge1_000444 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCN(CC2)C(=O)OC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M05 compound treatment 828280.0 -126000.0 -0.62 794460.0 -156000.0 -0.93 854500.0 -185643.4375 -1.0632713813231 -1.5064 -0.9775 2069602 Maybridge1_000445 [O-][N+](=O)c1ccc(nc1)N2CCCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M06 compound treatment 780180.0 -174000.0 -0.85 711470.0 -239000.0 -1.42 876960.0 -163183.4375 -0.934631901543388 -1.8527 -0.9732 1581293 Maybridge1_000446 C1CN(CCN1)c2ncnc3scc(c4ccccc4)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M07 compound treatment 932100.0 -22100.0 -0.11 924480.0 -26400.0 -0.16 995090.0 -45053.4375 -0.258043221829367 -0.3022 -0.9416 1364451 Maybridge1_000447 Clc1ccc(CN2CCCN(CC2)C(=O)Nc3cccc(Cl)c3Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M08 compound treatment 894160.0 -60100.0 -0.29 846190.0 -105000.0 -0.62 953600.0 -86543.4375 -0.495676882384135 -0.8152 -0.9609 1658768 Maybridge1_000448 Cc1nc(nc(N2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)c1Cl)c6ccccn6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M09 compound treatment 579940.0 -374000.0 -1.83 520660.0 -430000.0 -2.56 581790.0 -458353.4375 -2.62521583950316 -4.0487 -0.9883 2069603 Maybridge1_000449 OC(CNCCNc1ncccc1C(F)(F)F)COc2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M10 compound treatment 750430.0 -204000.0 -1.0 714650.0 -236000.0 -1.41 888530.0 -151613.4375 -0.868364814230333 -1.8874 -0.9786 2069604 Maybridge1_000450 CC(=O)c1ccc(OCc2c(F)cccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M11 compound treatment 1212900.0 259000.0 1.26 886760.0 -64200.0 -0.38 1283920.0 243776.5625 1.39622841418012 1.3155 0.6846 2069605 Maybridge1_000451 FC(F)(F)c1ccnc(NCCNC(=O)c2ccco2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M12 compound treatment 499390.0 -455000.0 -2.22 498720.0 -452000.0 -2.69 540890.0 -499253.4375 -2.85947027952943 -4.4865 -0.9946 1301777 Maybridge1_000452 Nc1oc(cc1C#N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M13 compound treatment 991360.0 37100.0 0.18 861090.0 -89800.0 -0.53 1084270.0 44126.5625 0.252734552291486 -0.0578 -0.0935 1198042 Maybridge1_000453 S=C(NC1CCN(Cc2ccccc2)CC1)Nc3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M14 compound treatment 1009390.0 55200.0 0.27 1051530.0 101000.0 0.6 1115610.0 75466.5625 0.432234164771274 0.7505 0.9552 2069606 Maybridge1_000454 CCCCCc1ccc(cc1)C(=O)O/N=C/c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M15 compound treatment 722660.0 -232000.0 -1.13 748330.0 -203000.0 -1.2 832350.0 -207793.4375 -1.19013533845224 -2.0359 -0.9996 1500883 Maybridge1_000455 CCCc1cnc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M16 compound treatment 917710.0 -36500.0 -0.18 888960.0 -62000.0 -0.37 950360.0 -89783.4375 -0.514233957828759 -0.6127 -0.9321 1229893 Maybridge1_000456 COc1cccc(NC(=S)NCc2ccco2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M17 compound treatment 1070400.0 116000.0 0.57 912560.0 -38400.0 -0.23 1156580.0 116436.5625 0.666889529267028 0.581 0.642 2069607 Maybridge1_000457 FC(F)(F)c1cnc(NCCCN2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M18 compound treatment 556260.0 -398000.0 -1.94 599360.0 -352000.0 -2.09 470400.0 -569743.4375 -3.26320122029842 -4.2136 -0.9718 1497535 Maybridge1_000458 OC1(CC(=O)c2ccc3ccccc3c2)C(=O)Nc4ccc(Br)cc41 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M19 compound treatment 915780.0 -38500.0 -0.19 856080.0 -94800.0 -0.56 1111520.0 71376.5625 0.408808720768647 -0.1981 -0.2745 2069608 Maybridge1_000459 Cc1nc(ccc1NC(=O)N2CCCN(Cc3c(F)cccc3Cl)CC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M20 compound treatment 704060.0 -250000.0 -1.22 732290.0 -219000.0 -1.3 878990.0 -161153.4375 -0.923005091928392 -1.9892 -0.9901 1920853 Maybridge1_000460 C/C(=N\N=C(/C)\c1ccc(F)cc1)/c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M21 compound treatment 955840.0 1600.0 0.01 921040.0 -29900.0 -0.18 1041770.0 1626.5625 0.00931612439132597 -0.0927 -0.5204 1742985 Maybridge1_000461 COc1ccccc1C2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M22 compound treatment 793490.0 -161000.0 -0.79 743260.0 -208000.0 -1.23 790300.0 -249843.4375 -1.43097639476287 -1.9926 -0.9735 2069609 Maybridge1_000462 COC(=O)c1sc2ccccc2c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M23 mock treatment 989690.0 35500.0 0.17 954980.0 4060.0 0.02 1162960.0 122816.5625 0.703430930914158 0.5201 0.7175 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 M24 mock treatment 901830.0 -52400.0 -0.26 1068880.0 118000.0 0.7 959100.0 -81043.4375 -0.464175674067644 -0.0108 -0.0123 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N01 compound treatment 974080.0 19800.0 0.1 1045350.0 94400.0 0.56 1155360.0 115216.5625 0.659901988513189 0.7612 0.873 1061248 Maybridge1_000463 CC(=NNC(=O)c1cccnc1)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N02 compound treatment 1071790.0 118000.0 0.57 966050.0 15100.0 0.09 1178400.0 138256.5625 0.791863413897181 0.8407 0.8558 2069610 Maybridge1_000464 Fc1ccc(NC(=O)CSC(=O)c2sc3ccccc3c2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N03 compound treatment 929010.0 -25200.0 -0.12 998130.0 47200.0 0.28 1012510.0 -27633.4375 -0.158270303852408 -5.0E-4 -0.0013 1918851 Maybridge1_000465 C(C/N=C/c1ccc2OCOc2c1)/N=C/c3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N04 compound treatment 829440.0 -125000.0 -0.61 944800.0 -6120.0 -0.04 1007680.0 -32463.4375 -0.185934092246708 -0.4804 -0.7524 2069611 Maybridge1_000466 COc1ccc(cc1)c2nnc(S)n2c3ccc(Cl)cc3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N05 compound treatment 1015770.0 61500.0 0.3 1098170.0 147000.0 0.88 1080960.0 40816.5625 0.233776552377379 0.8141 0.8526 1155620 Maybridge1_000467 Cc1ccc2nc(oc(=O)c2c1)c3sc4ccccc4c3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N06 compound treatment 896810.0 -57400.0 -0.28 973990.0 23100.0 0.14 1003910.0 -36233.4375 -0.207526738674558 -0.2026 -0.5403 1731343 Maybridge1_000468 COc1ccc(CC2N(CCc3cc(OC)c(OC)cc23)C(=S)Nc4ccc(Cl)cc4C)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N07 compound treatment 1012890.0 58700.0 0.29 1061010.0 110000.0 0.65 1149140.0 108996.5625 0.624276985653447 0.9038 0.9525 1680835 Maybridge1_000469 COc1cccc(NC(=S)Nc2ccc(OC)c(OC)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N08 compound treatment 787620.0 -167000.0 -0.81 827450.0 -123000.0 -0.73 868980.0 -171163.4375 -0.980337291064406 -1.4599 -0.9927 1443259 Maybridge1_000470 Cc1cccc2CCCN(C(=S)Nc3ccccc3Cl)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N09 compound treatment 926890.0 -27300.0 -0.13 962260.0 11300.0 0.07 1023300.0 -16843.4375 -0.0964706606278729 -0.0939 -0.5275 1532986 Maybridge1_000471 CCOC(=O)C1CCN(CC1)C(=S)Nc2cccc(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N10 compound treatment 911560.0 -42700.0 -0.21 915070.0 -35900.0 -0.21 1017800.0 -22343.4375 -0.127971868944364 -0.3174 -0.978 2069612 Maybridge1_000472 Oc1ccc(CCC(=O)N/N=C/C=C/c2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N11 compound treatment 1038400.0 84200.0 0.41 917480.0 -33400.0 -0.2 1079460.0 39316.5625 0.225185313745609 0.2526 0.496 1025368 Maybridge1_000473 CC1CC(=O)Nc2ccccc2N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N12 compound treatment 679200.0 -275000.0 -1.34 780660.0 -170000.0 -1.01 701660.0 -338483.4375 -1.93866132297628 -2.4797 -0.966 2069613 Maybridge1_000474 Fc1ccc(cc1)N(Cc2ccc3OCOc3c2)C(=S)Nc4ccc(Cl)c(Cl)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N13 compound treatment 1048180.0 93900.0 0.46 958080.0 7160.0 0.04 1204590.0 164446.5625 0.941866440407891 0.8334 0.7947 1356457 Maybridge1_000475 CC1CC(=O)Nc2ccccc2N1C(=O)c3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N14 compound treatment 521870.0 -432000.0 -2.11 529780.0 -421000.0 -2.5 556820.0 -483323.4375 -2.76823132526003 -4.2638 -0.9941 2069614 Maybridge1_000476 Oc1c(Cl)cc(Cl)cc1/C=N/Cc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N15 compound treatment 296230.0 -658000.0 -3.21 322850.0 -628000.0 -3.73 339550.0 -700593.4375 -4.01264360360986 -6.3292 -0.9959 2069615 Maybridge1_000477 Clc1cc(Cl)cc(/C=N/Cc2ccccc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N16 compound treatment 945610.0 -8630.0 -0.04 884190.0 -66700.0 -0.4 1072380.0 32236.5625 0.184634667403653 -0.1468 -0.334 2069616 Maybridge1_000478 Oc1ccc(CCc2nnc(S)n2c3cccc(c3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N17 compound treatment 935580.0 -18700.0 -0.09 862140.0 -88800.0 -0.53 950190.0 -89953.4375 -0.51520763154036 -0.6549 -0.8811 1635176 Maybridge1_000479 COc1ccc(CN(Cc2ccccc2)C(=S)Nc3c(C)cccc3C)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N18 compound treatment 940600.0 -13600.0 -0.07 972160.0 21200.0 0.13 1079610.0 39466.5625 0.226044437608786 0.165 0.617 2069617 Maybridge1_000480 Cc1ccc(NS(=O)(=O)C)cc1NC(=S)Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N19 compound treatment 1004660.0 50400.0 0.25 937220.0 -13700.0 -0.08 1203050.0 162906.5625 0.933046102079274 0.6339 0.6545 1041825 Maybridge1_000481 COC(=O)c1cccc([N+](=O)[O-])c1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N20 compound treatment 824800.0 -129000.0 -0.63 933010.0 -17900.0 -0.11 1036000.0 -4143.4375 -0.023731506878884 -0.4403 -0.6861 1733240 Maybridge1_000482 Cc1ccc(NS(=O)(=O)C)cc1NC(=S)Nc2cccc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N21 compound treatment 505780.0 -448000.0 -2.19 547800.0 -403000.0 -2.4 530900.0 -509243.4375 -2.91668792881702 -4.333 -0.9926 1669077 Maybridge1_000483 Cc1onc(c1C(=O)N2CCCc3cc(C)ccc23)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N22 compound treatment 801760.0 -152000.0 -0.74 812960.0 -138000.0 -0.82 1022470.0 -17673.4375 -0.101224479337453 -0.9622 -0.8647 2069618 Maybridge1_000484 CC1=NN(C(=O)C1)c2ccc(/N=C/c3ccc(Cl)c(Cl)c3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N23 mock treatment 1156080.0 202000.0 0.99 1034890.0 84000.0 0.5 1124540.0 84396.5625 0.483380672092414 1.1367 0.9422 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 N24 mock treatment 913200.0 -41000.0 -0.2 988280.0 37400.0 0.22 959060.0 -81083.4375 -0.464404773764491 -0.2556 -0.4627 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O01 compound treatment 754260.0 -200000.0 -0.98 722290.0 -229000.0 -1.36 796330.0 -243813.4375 -1.39643961546315 -2.1553 -0.9886 1915043 Maybridge1_000485 CCOC(=O)c1c(N)scc1c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O02 compound treatment 1134640.0 180000.0 0.88 1129760.0 179000.0 1.06 1234090.0 193946.5625 1.11082746683271 1.7642 0.9953 1150030 Maybridge1_000486 COc1ccccc1NC(=O)N2CCCN(CC2)C(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O03 compound treatment 781010.0 -173000.0 -0.85 838460.0 -112000.0 -0.67 800830.0 -239313.4375 -1.37066589956784 -1.6661 -0.9552 2069619 Maybridge1_000487 c1csc(c1)c2csc(n2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O04 compound treatment 1252590.0 298000.0 1.46 1056230.0 105000.0 0.63 1183360.0 143216.5625 0.820271776306235 1.6767 0.9388 1324207 Maybridge1_000488 COc1ccccc1NC(=O)N2CCN(CC2)C(=O)OC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O05 compound treatment 1000480.0 46200.0 0.23 987360.0 36400.0 0.22 1086240.0 46096.5625 0.264017712361211 0.408 0.9962 1231382 Maybridge1_000489 OC1CCN(CC1)C(=S)NCCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O06 compound treatment 1078240.0 124000.0 0.61 1014200.0 63300.0 0.38 990200.0 -49943.4375 -0.286050659768939 0.4019 0.523 1249375 Maybridge1_000490 Fc1cccc(Cl)c1CN2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O07 compound treatment 1038500.0 84300.0 0.41 1124910.0 174000.0 1.03 1141540.0 101396.5625 0.580748043252478 1.1703 0.9319 2069620 Maybridge1_000491 OC(=O)CSCC(=O)NCCNc1nccc(n1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O08 compound treatment 890140.0 -64100.0 -0.31 890420.0 -60500.0 -0.36 937410.0 -102733.4375 -0.588404984683043 -0.7282 -0.9614 2069621 Maybridge1_000492 Brc1ccc(NC(=O)CN2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O09 compound treatment 1145520.0 191000.0 0.93 1046640.0 95700.0 0.57 1418810.0 378666.5625 2.16880986687312 2.1204 0.8729 2069622 Maybridge1_000493 OCCN1CCN(CC1)c2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O10 compound treatment 759840.0 -194000.0 -0.95 842410.0 -109000.0 -0.65 830640.0 -209503.4375 -1.19992935049246 -1.6137 -0.9716 1549615 Maybridge1_000494 COc1ccc(CCNc2ncnc3scc(c4ccc(C)cc4)c23)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O11 compound treatment 1069350.0 115000.0 0.56 996860.0 45900.0 0.27 1214720.0 174576.5625 0.999885938634447 1.0597 0.8986 2069623 Maybridge1_000495 FC(F)(F)c1ccnc(NCCNC(=O)c2ccccc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O12 compound treatment 886430.0 -67800.0 -0.33 833600.0 -117000.0 -0.7 762960.0 -277183.4375 -1.58756603755793 -1.5107 -0.8557 2069624 Maybridge1_000496 FC(F)(F)c1cnc(NCCNC(=O)C2=Cc3cc(Cl)ccc3OC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O13 compound treatment 1091730.0 137000.0 0.67 894960.0 -56000.0 -0.33 1114090.0 73946.5625 0.42352837629108 0.4402 0.5113 1702834 Maybridge1_000497 Cc1cc(c(C)cc1Cl)S(=O)(=O)N2CCCN(Cc3ccc(Cl)cc3Cl)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O14 compound treatment 941710.0 -12500.0 -0.06 1125560.0 175000.0 1.04 980990.0 -59153.4375 -0.338800864968009 0.3686 0.3369 2069625 Maybridge1_000498 CCCCCCCc1ccc(NC(=O)Nc2ccc(F)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O15 compound treatment 826300.0 -128000.0 -0.63 852930.0 -98000.0 -0.58 901450.0 -138693.4375 -0.794365612148684 -1.156 -0.9907 1280161 Maybridge1_000499 CCCc1cnc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(C)cc3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O16 compound treatment 952100.0 -2140.0 -0.01 990560.0 39600.0 0.24 1060120.0 19976.5625 0.114415610319983 0.1961 0.7479 2069626 Maybridge1_000500 Cc1ccccc1NC(=S)NCc2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O17 compound treatment 1074190.0 120000.0 0.59 991000.0 40100.0 0.24 1034360.0 -5783.4375 -0.0331245944496196 0.4568 0.7211 2069627 Maybridge1_000501 OC(=O)c1ccccc1C(=O)NCCNc2ccc(cn2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O18 compound treatment 320820.0 -633000.0 -3.09 485440.0 -465000.0 -2.77 258880.0 -781263.4375 -4.47468041722647 -5.9683 -0.9777 1569206 Maybridge1_000502 CCc1cc2c(cc1C(=O)CC3(O)C(=O)Nc4ccc(Br)cc43)C(C)(C)CCC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O19 compound treatment 523240.0 -431000.0 -2.11 573400.0 -378000.0 -2.24 292040.0 -748103.4375 -4.28475676854013 -4.9857 -0.945 2069628 Maybridge1_000503 CCOC(=O)c1c(N)sc(C)c1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O20 compound treatment 812260.0 -142000.0 -0.69 854810.0 -96100.0 -0.57 937280.0 -102863.4375 -0.589149558697797 -1.0706 -0.9962 2069629 Maybridge1_000504 Oc1ccccc1/C=N/c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O21 compound treatment 1004990.0 50800.0 0.25 960430.0 9510.0 0.06 1091840.0 51696.5625 0.29609166991982 0.3468 0.8884 1609990 Maybridge1_000505 Clc1ccc(CN2CCCN(CC2)c3ncnc4scc(c5ccccc5)c34)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O22 compound treatment 283220.0 -671000.0 -3.28 324240.0 -627000.0 -3.73 383380.0 -656763.4375 -3.76160761078953 -6.2162 -0.9981 2069630 Maybridge1_000506 NNC(=O)c1sc2ccccc2c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O23 mock treatment 1198320.0 244000.0 1.19 1089920.0 139000.0 0.83 1265820.0 225676.5625 1.29256080135676 1.912 0.9839 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 O24 mock treatment 828910.0 -125000.0 -0.61 860810.0 -90100.0 -0.54 1044220.0 4076.5625 0.0233484808232175 -0.6494 -0.7978 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P01 compound treatment 894080.0 -60200.0 -0.29 913390.0 -37500.0 -0.22 924570.0 -115573.4375 -0.661945987370997 -0.6807 -0.8982 2069631 Maybridge1_000507 O=C(N/N=C/c1ccco1)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P02 compound treatment 1073190.0 119000.0 0.58 1032480.0 81600.0 0.48 1174750.0 134606.5625 0.770958066559873 1.0607 0.9817 2069632 Maybridge1_000508 Clc1c(sc2ccccc12)C(=O)SCC(=O)Nc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P03 compound treatment 971690.0 17500.0 0.09 1001730.0 50800.0 0.3 1155210.0 115066.5625 0.659042864650012 0.6042 0.8276 1982147 Maybridge1_000509 Cc1cc2CSC(SCc2cc1C)c3cc(Cl)cc(Cl)c3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P04 compound treatment 987210.0 33000.0 0.16 995060.0 44100.0 0.26 1036610.0 -3533.4375 -0.020237736501964 0.2329 0.7545 2069633 Maybridge1_000510 COc1ccc(cc1)c2nnc(S)n2c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P05 compound treatment 1081850.0 128000.0 0.62 1084540.0 134000.0 0.79 1243520.0 203376.5625 1.16483772036444 1.4912 0.9672 2069634 Maybridge1_000511 Cc1cc(C)c(/N=C/2\SC(=C)C3(CCCCC3)N2C(=O)c4c(Cl)sc5ccccc45)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P06 compound treatment 1073830.0 120000.0 0.58 1164200.0 213000.0 1.27 1257170.0 217026.5625 1.24301799191355 1.7872 0.956 2069635 Maybridge1_000512 CCCCCCC(C)(SCC(=O)O)SCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P07 compound treatment 887950.0 -66300.0 -0.32 924870.0 -26100.0 -0.15 940980.0 -99163.4375 -0.56795783673943 -0.6043 -0.8994 1444113 Maybridge1_000513 COc1ccccc1NC(=S)Nc2ccc(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P08 compound treatment 783470.0 -171000.0 -0.83 847570.0 -103000.0 -0.61 971150.0 -68993.4375 -0.395159390392422 -1.0647 -0.96 2069636 Maybridge1_000514 Cc1ccc2N(CCCc2c1)C(=S)Nc3cccc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P09 compound treatment 884640.0 -69600.0 -0.34 1042410.0 91500.0 0.54 1078510.0 38366.5625 0.219744195945488 0.2446 0.3608 1715015 Maybridge1_000515 CCOC(=O)C1CCN(CC1)C(=S)Nc2cccc(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P10 compound treatment 500160.0 -454000.0 -2.22 527070.0 -424000.0 -2.52 556770.0 -483373.4375 -2.76851769988109 -4.3345 -0.996 2069637 Maybridge1_000516 CN(C)c1ccc(/C=N/NC(=O)CCc2ccc(O)cc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P11 compound treatment 809200.0 -145000.0 -0.71 709000.0 -242000.0 -1.44 786090.0 -254053.4375 -1.45508913785604 -2.0798 -0.9605 2069638 Maybridge1_000517 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3[nH]cnc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P12 compound treatment 986730.0 32500.0 0.16 1016710.0 65800.0 0.39 1003850.0 -36293.4375 -0.207870388219828 0.1975 0.4197 2069639 Maybridge1_000518 CS(=O)(=O)N1CCCc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P13 compound treatment 797920.0 -156000.0 -0.76 775160.0 -176000.0 -1.05 865950.0 -174193.4375 -0.997691593100583 -1.6204 -0.9915 2069640 Maybridge1_000519 CC1CC(=O)Nc2ccccc2N1C(=O)c3ccc(cc3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P14 compound treatment 877250.0 -77000.0 -0.38 1023230.0 72300.0 0.43 1122780.0 82636.5625 0.473300285431137 0.3043 0.4102 1083099 Maybridge1_000520 CC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P15 compound treatment 266600.0 -688000.0 -3.36 287050.0 -664000.0 -3.95 269090.0 -771053.4375 -4.41620271960622 -6.7686 -0.9939 2069641 Maybridge1_000521 Brc1cccc(/C=N/Cc2ccccc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P16 compound treatment 1009410.0 55200.0 0.27 1093360.0 142000.0 0.85 1025280.0 -14863.4375 -0.0851302256339361 0.5955 0.6669 2069642 Maybridge1_000522 Cc1onc(c1NC(=O)NNC(=O)c2c(C)onc2c3ccccc3)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P17 compound treatment 993790.0 39600.0 0.19 945560.0 -5360.0 -0.03 1112750.0 72606.5625 0.415853536446699 0.3333 0.725 1164239 Maybridge1_000523 COc1cc(CN(Cc2ccccc2)C(=S)Nc3c(C)cccc3C)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P18 compound treatment 794890.0 -159000.0 -0.78 915840.0 -35100.0 -0.21 876000.0 -164143.4375 -0.940130294267721 -1.1127 -0.8986 1478744 Maybridge1_000524 Cc1ccc(NS(=O)(=O)C)cc1NC(=S)Nc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P19 compound treatment 916180.0 -38100.0 -0.19 858100.0 -92800.0 -0.55 1105000.0 64856.5625 0.371465470182552 -0.2116 -0.3063 2069643 Maybridge1_000525 Fc1ccc(/N=C/c2ccc3OCOc3c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P20 compound treatment 832180.0 -122000.0 -0.6 779700.0 -171000.0 -1.02 931920.0 -108223.4375 -0.619848918075323 -1.29 -0.9679 2069644 Maybridge1_000526 COCCCNC(=S)Nc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P21 compound treatment 730590.0 -224000.0 -1.09 888760.0 -62200.0 -0.37 984000.0 -56143.4375 -0.321561112780256 -1.0299 -0.8601 2069645 Maybridge1_000527 Cc1ccc(cc1Cl)N2C(SCC2=O)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P22 compound treatment 979080.0 24800.0 0.12 1039630.0 88700.0 0.53 881760.0 -158383.4375 -0.907139937921723 -0.1491 -0.1412 2069646 Maybridge1_000528 COCCCNC(=S)Nc1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P23 mock treatment 1022130.0 67900.0 0.33 1018200.0 67300.0 0.4 1273650.0 233506.5625 1.3374070670146 1.1946 0.8326 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.542 P24 mock treatment 946560.0 -7680.0 -0.04 934080.0 -16800.0 -0.1 846440.0 -193703.4375 -1.10943497023781 -0.72 -0.646 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A01 compound treatment 779150.0 -355000.0 -1.74 892010.0 -179000.0 -1.07 835230.0 -276981.25 -1.58640801018403 -2.5335 -0.9813 1349488 Maybridge1_000529 CCOC(=O)C1=C(C)N(C(=O)C1CC(=O)Nc2ccc(F)cc2)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A02 compound treatment 920090.0 -214000.0 -1.05 933440.0 -138000.0 -0.82 880990.0 -231221.25 -1.32431795699082 -1.8424 -0.9817 2069647 Maybridge1_000530 FC(F)(F)c1cccc(NC(=S)N2CCCCC2CCN3CCOCC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A03 compound treatment 953600.0 -181000.0 -0.88 926340.0 -145000.0 -0.86 888770.0 -223441.25 -1.27975806595404 -1.7465 -0.9823 1364330 Maybridge1_000531 OC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A04 compound treatment 670400.0 -464000.0 -2.27 684490.0 -387000.0 -2.3 633960.0 -478251.25 -2.73918040979497 -4.2183 -0.9961 2069648 Maybridge1_000532 [O-][N+](=O)c1ccc2NC(NC(=O)c2c1)c3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A05 compound treatment 976120.0 -158000.0 -0.77 965820.0 -106000.0 -0.63 946560.0 -165651.25 -0.948766278934032 -1.3563 -0.9862 2069649 Maybridge1_000533 Clc1ccc(/C=N/N=C(\C(=O)c2ccccc2)/c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A06 compound treatment 959770.0 -175000.0 -0.85 872680.0 -199000.0 -1.18 935360.0 -176851.25 -1.01291419405125 -1.7593 -0.9914 1933703 Maybridge1_000534 COc1ccc(CCNC(=O)c2ccc(cc2)[N+](=O)[O-])cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A07 compound treatment 901240.0 -233000.0 -1.14 896000.0 -175000.0 -1.04 885320.0 -226891.25 -1.29951791480711 -2.0098 -0.9959 1547043 Maybridge1_000535 Clc1c(sc2ccccc12)C(=O)Nc3ccc4[nH]nnc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A08 compound treatment 939040.0 -195000.0 -0.95 849860.0 -221000.0 -1.32 867290.0 -244921.25 -1.40278460316099 -2.1212 -0.9876 2069650 Maybridge1_000536 FC(F)(F)c1ccc(N2CCCCC2)c(NC=C(C#N)C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A09 compound treatment 972490.0 -162000.0 -0.79 906790.0 -165000.0 -0.98 935690.0 -176521.25 -1.01102412155226 -1.6052 -0.9946 1471479 Maybridge1_000537 CCOC(=O)c1ccc(cc1)N2CC3CCCCN3C2c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A10 compound treatment 891300.0 -243000.0 -1.19 824970.0 -246000.0 -1.47 831050.0 -281161.25 -1.61034892850456 -2.4611 -0.9925 1441228 Maybridge1_000538 COc1cc(CNc2cccc(F)c2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A11 compound treatment 253760.0 -881000.0 -4.3 259360.0 -812000.0 -4.83 269790.0 -842421.25 -4.82496132481618 -8.0574 -0.9986 1248791 Maybridge1_000539 Fc1ccc(NC(=S)Nc2ccc(Cl)cc2C(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A12 compound treatment 897680.0 -237000.0 -1.16 831010.0 -240000.0 -1.43 946370.0 -165841.25 -0.949854502494056 -2.0411 -0.9864 1664786 Maybridge1_000540 CCOC(=O)c1c[nH]c2c(F)cccc2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A13 compound treatment 904180.0 -230000.0 -1.12 866610.0 -205000.0 -1.22 915770.0 -196441.25 -1.12511577058217 -2.0017 -0.9993 2069651 Maybridge1_000541 COc1cccc(C2SCc3cc(C)c(C)cc3CS2)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A14 compound treatment 736610.0 -398000.0 -1.94 705440.0 -366000.0 -2.18 664930.0 -447281.25 -2.56179996951102 -3.8572 -0.9935 2069652 Maybridge1_000542 COc1c(/N=C/c2cc(Br)ccc2O)c(C)c(/N=C/c3cc(Br)ccc3O)cc1C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A15 compound treatment 857400.0 -277000.0 -1.35 741760.0 -330000.0 -1.96 742750.0 -369461.25 -2.11608650929477 -3.1344 -0.9839 2069653 Maybridge1_000543 COc1ccccc1/N=C\2/NC(C)(C)C(=C)S2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A16 compound treatment 805320.0 -329000.0 -1.61 836540.0 -235000.0 -1.4 837170.0 -275041.25 -1.57529667488694 -2.6437 -0.9982 1304585 Maybridge1_000544 Clc1ccc(Cl)c(NC(=S)N(CCc2ccccc2)CCc3ccccn3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A17 compound treatment 1012330.0 -122000.0 -0.6 900280.0 -171000.0 -1.02 945390.0 -166821.25 -0.955467445066813 -1.4831 -0.9773 2069654 Maybridge1_000545 FC(F)(F)c1cc(NC(=O)c2cc3ccccc3oc2=O)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A18 compound treatment 26240.0 -1110000.0 -5.41 26370.0 -1040000.0 -6.21 25380.0 -1086831.25 -6.22481774747684 -10.3073 -0.998 2069655 Maybridge1_000546 [O-][N+](=O)c1ccc(C=C2C(=O)NC(=S)NC2=O)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A19 compound treatment 847070.0 -287000.0 -1.4 901280.0 -170000.0 -1.01 820350.0 -291861.25 -1.67163309741119 -2.3593 -0.9808 1673765 Maybridge1_000547 CC(=O)Nc1ccc(C)c(NC(=S)Nc2ccc(Cl)cc2C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A20 compound treatment 999380.0 -135000.0 -0.66 855520.0 -216000.0 -1.28 878330.0 -233881.25 -1.33955308683116 -1.895 -0.9625 1676755 Maybridge1_000548 Cc1ncc(CSCC(=O)Nc2ccccc2F)c(CO)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A21 compound treatment 593760.0 -541000.0 -2.64 679540.0 -392000.0 -2.33 673200.0 -439011.25 -2.51443360718786 -4.3217 -0.9987 1714954 Maybridge1_000549 CC(C)c1ccc(cc1)N(CCc2ccccn2)C(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A22 compound treatment 541130.0 -593000.0 -2.9 614440.0 -457000.0 -2.72 552350.0 -559861.25 -3.20660106628749 -5.0933 -0.9976 2069656 Maybridge1_000550 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A23 mock treatment 840500.0 -294000.0 -1.44 937210.0 -134000.0 -0.8 871790.0 -240421.25 -1.37701088726568 -2.0844 -0.9726 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 A24 mock treatment 808720.0 -326000.0 -1.59 817220.0 -254000.0 -1.51 880410.0 -231801.25 -1.3276399025951 -2.5575 -0.9972 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B01 compound treatment 1009010.0 -125000.0 -0.61 981710.0 -89600.0 -0.53 983210.0 -129001.25 -0.738853681697776 -1.0878 -0.991 1706179 Maybridge1_000551 Clc1ccc(cc1Cl)C2N(Cc3ccccc3)CCC4CCCCN24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B02 compound treatment 1021960.0 -112000.0 -0.55 1002560.0 -68800.0 -0.41 934000.0 -178211.25 -1.02070358374406 -1.1424 -0.9295 2069657 Maybridge1_000552 [O-][N+](=O)c1cc(Cl)c(cc1N2CCCCC2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B03 compound treatment 970110.0 -164000.0 -0.8 994020.0 -77300.0 -0.46 924070.0 -188141.25 -1.07757758348638 -1.3509 -0.9513 2069658 Maybridge1_000553 CCC(C(=O)NNC(=O)c1ccccc1N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B04 compound treatment 702900.0 -431000.0 -2.11 703120.0 -368000.0 -2.19 634790.0 -477421.25 -2.73442659108539 -4.0599 -0.993 1375753 Maybridge1_000554 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)Nc2cccc3cccnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B05 compound treatment 760500.0 -374000.0 -1.83 727460.0 -344000.0 -2.04 802560.0 -309651.25 -1.77352518758399 -3.2591 -0.9981 2069659 Maybridge1_000555 [O-][N+](=O)c1ccccc1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B06 compound treatment 809080.0 -325000.0 -1.59 758340.0 -313000.0 -1.86 790940.0 -321271.25 -1.8400786495181 -3.0545 -0.9976 2069660 Maybridge1_000556 CC1(C)CCC(C)(C)N=C(N1)SCC(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B07 compound treatment 872350.0 -262000.0 -1.28 788000.0 -283000.0 -1.68 858180.0 -254031.25 -1.45496205911794 -2.5518 -0.9937 2069661 Maybridge1_000557 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=S)Nc2cccc(Cl)c2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B08 compound treatment 948320.0 -186000.0 -0.91 963240.0 -108000.0 -0.64 881470.0 -230741.25 -1.32156876062865 -1.6589 -0.96 2069662 Maybridge1_000558 Clc1ccc(cc1)S(=O)(=O)Nc2cccc(C#N)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B09 compound treatment 998350.0 -136000.0 -0.66 994900.0 -76500.0 -0.45 999590.0 -112621.25 -0.645037355838844 -1.0184 -0.9873 2069663 Maybridge1_000559 COc1cc([N+](=O)[O-])c(OC)cc1SCc2nnc(S)n2c3cccc(Cl)c3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B10 compound treatment 979680.0 -155000.0 -0.76 981120.0 -90200.0 -0.54 960570.0 -151641.25 -0.868524110113297 -1.2474 -0.9822 2069664 Maybridge1_000560 Cc1cccc(C)c1NC(=O)CSC(=O)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B11 compound treatment 1052060.0 -82300.0 -0.4 964340.0 -107000.0 -0.64 939690.0 -172521.25 -0.98811415186754 -1.1699 -0.9419 2069665 Maybridge1_000561 OCc1ccc(N2CCOCC2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B12 compound treatment 939910.0 -194000.0 -0.95 999390.0 -72000.0 -0.43 949120.0 -163091.25 -0.934103898335811 -1.3348 -0.9539 2069666 Maybridge1_000562 [O-][N+](=O)c1cccc(c1)c2noc(n2)c3c(F)cccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B13 compound treatment 834800.0 -300000.0 -1.46 853480.0 -218000.0 -1.3 793880.0 -318331.25 -1.82323982179983 -2.6456 -0.9898 2069667 Maybridge1_000563 Cc1ccc(cc1)S(=O)(=O)NNC(=O)CCc2nc(no2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B14 compound treatment 915300.0 -219000.0 -1.07 878140.0 -193000.0 -1.15 835710.0 -276501.25 -1.58365881382186 -2.1955 -0.9845 2069668 Maybridge1_000564 Cc1cc(Oc2ccc(cc2)[N+](=O)[O-])c(Cl)c(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B15 compound treatment 966260.0 -168000.0 -0.82 909760.0 -162000.0 -0.96 981440.0 -130771.25 -0.748991343283265 -1.4613 -0.9946 2069669 Maybridge1_000565 COC(=O)c1cc(ccc1n2cccc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B16 compound treatment 1043600.0 -90700.0 -0.44 1002250.0 -69100.0 -0.41 949280.0 -162931.25 -0.933187499548422 -1.0319 -0.9281 1590064 Maybridge1_000566 CC(C)(C#C)N1CNC(=S)NC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B17 compound treatment 940290.0 -194000.0 -0.95 1049450.0 -21900.0 -0.13 933280.0 -178931.25 -1.02482737828731 -1.2142 -0.866 2069670 Maybridge1_000567 Sc1nc2cc(Cl)c(Cl)cc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B18 compound treatment 926760.0 -208000.0 -1.01 987730.0 -83600.0 -0.5 891860.0 -220351.25 -1.26206011437259 -1.6012 -0.9454 2069671 Maybridge1_000568 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2ccc(Cl)cc2Sc3cc(Cl)ccc3OC(=O)c4ccc(cc4)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B19 compound treatment 734130.0 -400000.0 -1.96 747750.0 -324000.0 -1.92 709550.0 -402661.25 -2.30623925767796 -3.5714 -0.9965 2069672 Maybridge1_000569 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B20 compound treatment 966600.0 -168000.0 -0.82 875880.0 -195000.0 -1.16 1030840.0 -81371.25 -0.466053217676962 -1.4133 -0.9443 2069673 Maybridge1_000570 NC(=O)c1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B21 compound treatment 966660.0 -168000.0 -0.82 960690.0 -111000.0 -0.66 970640.0 -141571.25 -0.810848261432012 -1.321 -0.9953 2069674 Maybridge1_000571 Cc1ccc2cc(F)ccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B22 compound treatment 941290.0 -193000.0 -0.94 883550.0 -188000.0 -1.12 879680.0 -232531.25 -1.33182097206257 -1.9582 -0.9903 2069675 Maybridge1_000572 [O-][N+](=O)c1ccc(OC(=O)c2cccnc2Oc3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B23 mock treatment 1027040.0 -107000.0 -0.52 971480.0 -99900.0 -0.59 998530.0 -113681.25 -0.651108497805295 -1.0214 -0.9961 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 B24 mock treatment 979010.0 -155000.0 -0.76 885930.0 -185000.0 -1.1 903110.0 -209101.25 -1.19762582463431 -1.7662 -0.9833 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C01 compound treatment 1066880.0 -67400.0 -0.33 967780.0 -104000.0 -0.62 945060.0 -167151.25 -0.957357517565802 -1.0986 -0.927 1663724 Maybridge1_000573 CCOC(=O)C1=C(CC(=O)Nc2ccc(OC)cc2)C(=O)N(C1C)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C02 compound treatment 951220.0 -183000.0 -0.89 940450.0 -131000.0 -0.78 880900.0 -231311.25 -1.32483343130873 -1.7308 -0.9734 1566478 Maybridge1_000574 CSc1cccc(NC(=S)N2CCCCC2CCN3CCOCC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C03 compound treatment 1023680.0 -111000.0 -0.54 1036730.0 -34600.0 -0.21 1025930.0 -86281.25 -0.494175205464957 -0.7163 -0.9415 1208608 Maybridge1_000575 Cc1cc(Cl)ccc1Nc2nnc(s2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C04 compound treatment 1087590.0 -46700.0 -0.23 1067920.0 -3440.0 -0.02 964480.0 -147731.25 -0.846129614746482 -0.6321 -0.7211 2069676 Maybridge1_000576 Cc1ccccc1C(=O)N(c2nc3ccccc3s2)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C05 compound treatment 973220.0 -161000.0 -0.79 975790.0 -95600.0 -0.57 955220.0 -156991.25 -0.899166194566611 -1.3017 -0.9837 2069677 Maybridge1_000577 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)c3c(Cl)ccc(C)c3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C06 compound treatment 1018240.0 -116000.0 -0.57 1125840.0 54500.0 0.32 970740.0 -141471.25 -0.810275512189894 -0.6082 -0.5844 1323864 Maybridge1_000578 COc1ccc(CCNC(=O)c2c(Cl)cccc2Cl)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C07 compound treatment 84960.0 -1050000.0 -5.13 147920.0 -923000.0 -5.49 122810.0 -989401.25 -5.66678816088125 -9.4022 -0.9991 1488891 Maybridge1_000579 CC(C)N(Cc1ccc(cc1)N(C)C)C(=O)c2c(C)onc2c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C08 compound treatment 784440.0 -350000.0 -1.71 828990.0 -242000.0 -1.44 774310.0 -337901.25 -1.93532684848233 -2.9364 -0.993 1292706 Maybridge1_000580 COc1cc2CCNC(c3ccc(N)cc3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C09 compound treatment 964880.0 -169000.0 -0.83 1149280.0 77900.0 0.46 927930.0 -184281.25 -1.05546946274062 -0.8198 -0.5777 2069678 Maybridge1_000581 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(cc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C10 compound treatment 697930.0 -436000.0 -2.13 668090.0 -403000.0 -2.4 730960.0 -381251.25 -2.18361364494049 -3.8762 -0.9987 2069679 Maybridge1_000582 COc1ccc(CCNc2ccc(cc2N)C(F)(F)F)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C11 compound treatment 1013080.0 -121000.0 -0.59 847740.0 -224000.0 -1.33 858720.0 -253491.25 -1.4518692132105 -1.948 -0.9475 2069680 Maybridge1_000583 Cc1ccc(cc1[N+](=O)[O-])C2=N/C(=C\c3cccs3)/C(=O)O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C12 compound treatment 865670.0 -269000.0 -1.31 754850.0 -317000.0 -1.88 758650.0 -353561.25 -2.02501937979801 -3.0136 -0.9847 2069681 Maybridge1_000584 Fc1ccc(cc1)c2cn3Cc4ccccc4Cc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C13 compound treatment 1000100.0 -134000.0 -0.66 1082560.0 11200.0 0.07 1154560.0 42348.75 0.242552144671456 -0.2001 -0.2849 1396404 Maybridge1_000585 CC(=O)Nc1ccc(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C14 compound treatment 632250.0 -502000.0 -2.45 682200.0 -389000.0 -2.31 670880.0 -441331.25 -2.527721389605 -4.2117 -0.9993 2069682 Maybridge1_000586 CCC(C(=O)Nc1ccc(cc1)C(F)(F)F)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C15 compound treatment 761560.0 -373000.0 -1.82 746030.0 -325000.0 -1.93 731040.0 -381171.25 -2.1831554455468 -3.4289 -0.9971 2069683 Maybridge1_000587 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(C)c(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C16 compound treatment 946350.0 -188000.0 -0.92 966990.0 -104000.0 -0.62 937880.0 -174331.25 -0.998480913149876 -1.465 -0.982 2069684 Maybridge1_000588 FC(F)(F)c1cccc(NC(=S)N(CCc2ccccc2)CCc3ccccn3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C17 compound treatment 967760.0 -167000.0 -0.81 927870.0 -143000.0 -0.85 856080.0 -256131.25 -1.46698979320242 -1.8094 -0.9614 2069685 Maybridge1_000589 CCOC(=O)C1CCN(CC1)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C18 compound treatment 1029650.0 -105000.0 -0.51 1004330.0 -67000.0 -0.4 930010.0 -182201.25 -1.04355627850456 -1.1279 -0.918 2069686 Maybridge1_000590 Cc1c(NNc2cc3c(c([N+](=O)[O-])c2C)C(C)(C)CC3(C)C)cc4c(c1[N+](=O)[O-])C(C)(C)CC4(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C19 compound treatment 984280.0 -150000.0 -0.73 996070.0 -75300.0 -0.45 935120.0 -177091.25 -1.01428879223233 -1.2673 -0.9535 1235622 Maybridge1_000591 CC(=O)Nc1ccc(C)c(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C20 compound treatment 588970.0 -545000.0 -2.66 658440.0 -413000.0 -2.46 595200.0 -517011.25 -2.96117801603992 -4.6656 -0.997 2069687 Maybridge1_000592 [O-][N+](=O)c1ccc(/C=N/c2cc(ccc2N3CCOCC3)C(F)(F)F)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C21 compound treatment 878150.0 -256000.0 -1.25 974720.0 -96600.0 -0.57 910770.0 -201441.25 -1.15375323268807 -1.7205 -0.9576 2069688 Maybridge1_000593 Cc1ccc([N+](=O)[O-])c(c1)C(=O)N(CCc2ccccn2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C22 compound treatment 810200.0 -324000.0 -1.58 695040.0 -376000.0 -2.24 750740.0 -361471.25 -2.07032384484955 -3.4016 -0.9902 1931746 Maybridge1_000594 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C23 mock treatment 1130240.0 -4080.0 -0.02 927410.0 -144000.0 -0.86 986900.0 -125311.25 -0.717719234663621 -0.9201 -0.8235 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 C24 mock treatment 944480.0 -190000.0 -0.93 850100.0 -221000.0 -1.32 1084800.0 -27411.25 -0.156997726630077 -1.3858 -0.8568 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D01 compound treatment 1039040.0 -95300.0 -0.47 1000260.0 -71100.0 -0.42 930560.0 -181651.25 -1.04040615767292 -1.1135 -0.916 1042344 Maybridge1_000595 [O-][N+](=O)c1ccccc1N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D02 compound treatment 1098130.0 -36200.0 -0.18 1033040.0 -38300.0 -0.23 986790.0 -125421.25 -0.718349258829951 -0.6484 -0.8376 2069689 Maybridge1_000596 [O-][N+](=O)c1cc(Cl)c(cc1N2CCOCC2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D03 compound treatment 767640.0 -367000.0 -1.79 817950.0 -253000.0 -1.51 765780.0 -346431.25 -1.98418235883499 -3.0499 -0.9939 1508813 Maybridge1_000597 CN1C(NC(=O)c2cc(Cl)ccc12)C3CCC=CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D04 compound treatment 743130.0 -391000.0 -1.91 757180.0 -314000.0 -1.87 669600.0 -442611.25 -2.53505257990411 -3.6457 -0.9897 2069690 Maybridge1_000598 CC(C)(C)NNC(=S)Nc1cc(Cl)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D05 compound treatment 898960.0 -235000.0 -1.15 848510.0 -223000.0 -1.33 841930.0 -270281.25 -1.54803381096212 -2.3227 -0.9927 2069691 Maybridge1_000599 N#Cc1cnn(c1n2cccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D06 compound treatment 1309830.0 176000.0 0.86 919040.0 -152000.0 -0.91 880690.0 -231521.25 -1.32603620471717 -0.7934 -0.4358 1154273 Maybridge1_000600 Cc1ccc(NC(=O)c2c(F)cccc2Cl)c(c1)C(=O)Nc3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D07 compound treatment 899530.0 -235000.0 -1.15 1130800.0 59400.0 0.35 930530.0 -181681.25 -1.04057798244555 -1.059 -0.6666 2069692 Maybridge1_000601 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=S)Nc2cc(ccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D08 compound treatment 603650.0 -531000.0 -2.59 586320.0 -485000.0 -2.88 546190.0 -566021.25 -3.24188241960196 -5.0339 -0.9959 2069693 Maybridge1_000602 [O-][N+](=O)c1cc(ccc1N2CCCCC2)c3n[nH]c(=O)c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D09 compound treatment 949920.0 -184000.0 -0.9 925200.0 -146000.0 -0.87 935360.0 -176851.25 -1.01291419405125 -1.6067 -0.9978 2069694 Maybridge1_000603 COc1cc([N+](=O)[O-])c(OC)cc1SCc2nnc(S)n2c3cccc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D10 compound treatment 984520.0 -150000.0 -0.73 970490.0 -101000.0 -0.6 1072380.0 -39831.25 -0.228133182501135 -0.9006 -0.9252 2069695 Maybridge1_000604 COC(=O)C(C)SCC(=O)Nc1c(C)cccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D11 compound treatment 1020640.0 -114000.0 -0.56 917440.0 -154000.0 -0.92 913340.0 -198871.25 -1.13903357716564 -1.5067 -0.9639 2069696 Maybridge1_000605 Sc1nc2ccccc2c(=O)n1NC(=O)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D12 compound treatment 1225280.0 91000.0 0.44 943440.0 -128000.0 -0.76 1168160.0 55948.75 0.320446041599508 0.0024 0.0026 2069697 Maybridge1_000606 [O-][N+](=O)c1ccc(cc1)c2nc(no2)c3cccc(c3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D13 compound treatment 930350.0 -204000.0 -1.0 936640.0 -135000.0 -0.8 918820.0 -193391.25 -1.10764691869757 -1.6774 -0.9915 2069698 Maybridge1_000607 Clc1ccc(cc1)c2noc(CCC(=O)NNS(=O)(=O)c3ccc(Cl)cc3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D14 compound treatment 1009280.0 -125000.0 -0.61 1217680.0 146000.0 0.87 899540.0 -212671.25 -1.21807297257793 -0.5536 -0.3424 2069699 Maybridge1_000608 CC1CCC(C)(C)CN(C1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D15 compound treatment 1160650.0 26300.0 0.13 862520.0 -209000.0 -1.24 881020.0 -231191.25 -1.32414613221818 -1.4072 -0.7732 2069700 Maybridge1_000609 N#Cc1cccc(c1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D16 compound treatment 940490.0 -194000.0 -0.95 837760.0 -234000.0 -1.39 829990.0 -282221.25 -1.61642007047101 -2.282 -0.9785 2069701 Maybridge1_000610 [O-][N+](=O)c1ccc(c(C#N)c1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D17 compound treatment 1184900.0 50600.0 0.25 938510.0 -133000.0 -0.79 967320.0 -144891.25 -0.82986353627033 -0.7925 -0.6762 1031325 Maybridge1_000611 COc1ccccc1CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D18 compound treatment 1060830.0 -73500.0 -0.36 891680.0 -180000.0 -1.07 1070450.0 -41761.25 -0.239187242874013 -0.9623 -0.8351 1622063 Maybridge1_000612 Clc1ccc(OC(=O)c2cccs2)c(Sc3cc(Cl)ccc3OC(=O)c4cccs4)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D19 compound treatment 892500.0 -242000.0 -1.18 955450.0 -116000.0 -0.69 913780.0 -198431.25 -1.13651348050032 -1.7362 -0.9763 2069702 Maybridge1_000613 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D20 compound treatment 703480.0 -431000.0 -2.1 688600.0 -383000.0 -2.28 696320.0 -415891.25 -2.38201398241017 -3.9047 -0.9987 1152323 Maybridge1_000614 Cc1cc(ccc1Cl)c2csc(N)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D21 compound treatment 1071650.0 -62700.0 -0.31 950530.0 -121000.0 -0.72 947620.0 -164591.25 -0.942695136967581 -1.1359 -0.9278 1111385 Maybridge1_000615 CCOC(=O)CNC(=O)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D22 compound treatment 784700.0 -350000.0 -1.71 744570.0 -327000.0 -1.94 716870.0 -395341.25 -2.26431401315492 -3.4155 -0.9934 1353468 Maybridge1_000616 COc1ccc(OC(=O)c2cccnc2Oc3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D23 mock treatment 1024600.0 -110000.0 -0.54 964440.0 -107000.0 -0.64 986370.0 -125841.25 -0.720754805646847 -1.0927 -0.9929 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 D24 mock treatment 1143250.0 8930.0 0.04 954520.0 -117000.0 -0.69 965810.0 -146401.25 -0.838512049826312 -0.86 -0.7892 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E01 compound treatment 1059410.0 -74900.0 -0.37 939570.0 -132000.0 -0.78 1067170.0 -45041.25 -0.257973418015484 -0.8127 -0.9004 1374907 Maybridge1_000617 CCOC(=O)C1=C(C)N(C(=O)C1CC(=O)Nc2ccc(cc2)C(=O)OCC)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E02 compound treatment 597030.0 -537000.0 -2.63 583070.0 -488000.0 -2.9 650340.0 -461871.25 -2.64536408393604 -4.7193 -0.9989 2069703 Maybridge1_000618 Oc1c(Cl)cc(Cl)cc1/C=C/2\SC(=S)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E03 compound treatment 529050.0 -605000.0 -2.96 540440.0 -531000.0 -3.16 566400.0 -545811.25 -3.12612979776991 -5.335 -0.9996 2069704 Maybridge1_000619 Fc1ccc(Nc2nnc(s2)c3ccccc3Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E04 compound treatment 970350.0 -164000.0 -0.8 861240.0 -210000.0 -1.25 952480.0 -159731.25 -0.914859523800645 -1.7121 -0.982 1921741 Maybridge1_000620 [O-][N+](=O)c1cc(ccc1N2CCCCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E05 compound treatment 1047920.0 -86400.0 -0.42 1000840.0 -70500.0 -0.42 1018030.0 -94181.25 -0.539422395592281 -0.7972 -0.9927 1147994 Maybridge1_000621 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)c3cc(F)ccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E06 compound treatment 951550.0 -183000.0 -0.89 1043200.0 -28200.0 -0.17 926620.0 -185591.25 -1.06297247781237 -1.2259 -0.8767 2069705 Maybridge1_000622 [O-][N+](=O)c1cc(ccc1N2CCCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E07 compound treatment 1268000.0 134000.0 0.65 1035520.0 -35800.0 -0.21 1322900.0 210688.75 1.20671821885294 0.9508 0.6847 1265948 Maybridge1_000623 Clc1cccc(NC(=S)Nc2ccc(Cl)cc2C(=O)c3ccccc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E08 compound treatment 1132610.0 -1710.0 -0.01 990530.0 -80800.0 -0.48 981490.0 -130721.25 -0.748704968662206 -0.7146 -0.8031 1407219 Maybridge1_000624 COc1cc2CCN(C(c3cccc(C)c3)c2cc1OC)C(=O)c4sc5ccccc5c4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E09 compound treatment 1111850.0 -22500.0 -0.11 989440.0 -81900.0 -0.49 1126640.0 14428.75 0.0826405562721043 -0.2969 -0.5866 1372571 Maybridge1_000625 Cc1cccc(NC(=S)Nc2ccc(C)c(NS(=O)(=O)C)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E10 compound treatment 1163470.0 29200.0 0.14 1149520.0 78200.0 0.46 960240.0 -151971.25 -0.870414182612286 -0.1519 -0.1524 2069706 Maybridge1_000626 [O-][N+](=O)c1cc(ccc1NCCc2ccccc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E11 compound treatment 1124550.0 -9770.0 -0.05 1012160.0 -59200.0 -0.35 1044690.0 -67521.25 -0.386727447643616 -0.4541 -0.8647 2069707 Maybridge1_000627 CN(C)c1ccc(/C=C/2\N=C(OC2=O)c3ccc(C)c(c3)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E12 compound treatment 1218590.0 84300.0 0.41 1019010.0 -52300.0 -0.31 947740.0 -164471.25 -0.942007837877039 -0.4859 -0.4523 1239898 Maybridge1_000628 COc1ccc(cc1)C(=O)CC2(O)C(=O)N(CN3CCCCC3)c4ccc(Br)cc42 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E13 compound treatment 1171330.0 37000.0 0.18 1209540.0 138000.0 0.82 1010180.0 -102031.25 -0.584383211098546 0.2414 0.2357 2069708 Maybridge1_000629 Cc1onc(c1C(=O)Nc2ccc(C)c(c2)[N+](=O)[O-])c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E14 compound treatment 553090.0 -581000.0 -2.84 528230.0 -543000.0 -3.23 475650.0 -636561.25 -3.64589973499202 -5.6092 -0.9949 2069709 Maybridge1_000630 CCC(C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E15 compound treatment 1308200.0 174000.0 0.85 1136410.0 65100.0 0.39 1051590.0 -60621.25 -0.347207749937472 0.5134 0.5155 2069710 Maybridge1_000631 Cc1onc(c1C(=O)N(c2nc3ccccc3s2)c4cccc(Cl)c4)c5c(Cl)cccc5Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E16 compound treatment 787170.0 -347000.0 -1.7 729180.0 -342000.0 -2.03 742640.0 -369571.25 -2.1167165334611 -3.3761 -0.9957 1278441 Maybridge1_000632 Cc1ccc(C)c(NC(=S)N(CCc2ccccc2)CCc3ccccn3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E17 compound treatment 797350.0 -337000.0 -1.65 775260.0 -296000.0 -1.76 649840.0 -462371.25 -2.64822783014663 -3.4961 -0.9763 2069711 Maybridge1_000633 COc1cc(/C=C\2/SC(=S)NC2=O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E18 compound treatment 801120.0 -333000.0 -1.63 890080.0 -181000.0 -1.08 745000.0 -367211.25 -2.10319965134712 -2.7765 -0.9675 2069712 Maybridge1_000634 [O-][N+](=O)c1ccc(s1)C2NC(=O)c3ccccc3N2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E19 compound treatment 740930.0 -393000.0 -1.92 1048350.0 -23000.0 -0.14 804160.0 -308051.25 -1.7643611997101 -2.2073 -0.8449 1046617 Maybridge1_000635 CC(=O)Nc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E20 compound treatment 804970.0 -329000.0 -1.61 788320.0 -283000.0 -1.68 846250.0 -265961.25 -1.52329104370262 -2.7802 -0.9992 1935254 Maybridge1_000636 Cc1ccc(/C=N/NS(=O)(=O)c2ccc(C)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E21 compound treatment 1179730.0 45400.0 0.22 1006880.0 -64500.0 -0.38 951260.0 -160951.25 -0.921847064554485 -0.6255 -0.6116 2069713 Maybridge1_000637 CN(CCC#N)c1ccc(/C=N/CCC\N=C/c2ccc(cc2)N(C)CCC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E22 compound treatment 856160.0 -278000.0 -1.36 839580.0 -232000.0 -1.38 858730.0 -253481.25 -1.45181193828629 -2.4186 -0.9996 1699144 Maybridge1_000638 CN(C)c1ccc(CC(C#N)c2ccc(N)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E23 mock treatment 1213720.0 79400.0 0.39 1077290.0 5930.0 0.04 1082930.0 -29281.25 -0.167708137457684 0.1475 0.3479 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 E24 mock treatment 1076750.0 -57600.0 -0.28 1035220.0 -36100.0 -0.21 1066800.0 -45411.25 -0.260092590211321 -0.4366 -0.994 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F01 compound treatment 813620.0 -321000.0 -1.57 810560.0 -261000.0 -1.55 861150.0 -251061.25 -1.43795140662704 -2.6302 -0.9993 1013657 Maybridge1_000639 [O-][N+](=O)c1ccccc1N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F02 compound treatment 1132320.0 -2000.0 -0.01 1067040.0 -4320.0 -0.03 865600.0 -246611.25 -1.41246406535278 -0.8359 -0.5917 1060533 Maybridge1_000640 COc1ccc(CCNC(=O)c2ccccc2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F03 compound treatment 718600.0 -416000.0 -2.03 728560.0 -343000.0 -2.04 691470.0 -420741.25 -2.4097923206529 -3.7409 -0.9967 1243303 Maybridge1_000641 Nc1ccccc1C(=O)Nc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F04 compound treatment 947280.0 -187000.0 -0.91 901690.0 -170000.0 -1.01 864380.0 -247831.25 -1.41945160610662 -1.9296 -0.9812 2069714 Maybridge1_000642 NC(=O)C(C1CCCC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F05 compound treatment 927680.0 -207000.0 -1.01 915280.0 -156000.0 -0.93 869390.0 -242821.25 -1.39075686907651 -1.9217 -0.9839 2069715 Maybridge1_000643 N#CCc1nn(c(c1C#N)n2cccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F06 compound treatment 996320.0 -138000.0 -0.67 843430.0 -228000.0 -1.36 985130.0 -127081.25 -0.72785689624911 -1.592 -0.9478 2069716 Maybridge1_000644 FC(F)(F)c1cc(Br)ccc1NC(=O)C(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F07 compound treatment 723550.0 -411000.0 -2.01 713920.0 -357000.0 -2.13 726240.0 -385971.25 -2.21064740916846 -3.6622 -0.9992 2069717 Maybridge1_000645 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2c(S)nnc2CCc3nc(no3)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F08 compound treatment 923200.0 -211000.0 -1.03 876800.0 -195000.0 -1.16 820180.0 -292031.25 -1.67260677112279 -2.2292 -0.9775 2069718 Maybridge1_000646 CN(C)c1ccc(cc1[N+](=O)[O-])c2n[nH]c(=O)c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F09 compound treatment 962480.0 -172000.0 -0.84 944680.0 -127000.0 -0.75 944640.0 -167571.25 -0.959763064382698 -1.4738 -0.9951 1003095 Maybridge1_000647 Oc1nc(O)c2ccccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F10 compound treatment 990420.0 -144000.0 -0.7 1052180.0 -19200.0 -0.11 904230.0 -207981.25 -1.19121103312259 -1.1595 -0.8354 2069719 Maybridge1_000648 [O-][N+](=O)c1cccc(c1)c2ncon2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F11 compound treatment 448870.0 -685000.0 -3.35 447390.0 -624000.0 -3.71 451760.0 -660451.25 -3.78272952893401 -6.2597 -0.9986 2069720 Maybridge1_000649 N#C/C(=C\c1ccc[nH]1)/c2nn(c(c2C#N)n3cccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F12 compound treatment 1306190.0 172000.0 0.84 1021130.0 -50200.0 -0.3 1328100.0 215888.75 1.23650117944307 1.0263 0.6733 1572812 Maybridge1_000650 Cc1cc(Cl)cc2c(O)c(cnc12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F13 compound treatment 1141550.0 7230.0 0.04 1006490.0 -64900.0 -0.39 986520.0 -125691.25 -0.71989568178367 -0.6179 -0.7559 2069721 Maybridge1_000651 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NNC(=O)CCc2nc(no2)c3ccc(Cl)cc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F14 compound treatment 1127530.0 -6790.0 -0.03 1016680.0 -54700.0 -0.33 788400.0 -323811.25 -1.8546264802679 -1.2776 -0.6784 2069722 Maybridge1_000652 CC1(CC2CC(C)(C)C1)CN2c3ccc(cc3[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F15 compound treatment 846570.0 -288000.0 -1.41 865800.0 -206000.0 -1.22 794820.0 -317391.25 -1.81785597892392 -2.567 -0.9862 2069723 Maybridge1_000653 Cn1c(S)nnc1c2ccc(o2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F16 compound treatment 980280.0 -154000.0 -0.75 881550.0 -190000.0 -1.13 805530.0 -306681.25 -1.75651453509308 -2.1003 -0.9463 2069724 Maybridge1_000654 N/C(=N\OC(=O)c1ccc(cc1)[N+](=O)[O-])/c2cccc(c2)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F17 compound treatment 1031360.0 -103000.0 -0.5 980080.0 -91300.0 -0.54 1192100.0 79888.75 0.457562210162562 -0.3396 -0.3903 2069725 Maybridge1_000655 Cc1nc2c(Br)cc(Br)cc2c(=O)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F18 compound treatment 1178880.0 44600.0 0.22 1014190.0 -57200.0 -0.34 886030.0 -226181.25 -1.29545139518807 -0.8185 -0.6032 2069726 Maybridge1_000656 [O-][N+](=O)c1cc(ccc1Oc2ccc(C#N)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F19 compound treatment 914400.0 -220000.0 -1.07 938080.0 -133000.0 -0.79 862720.0 -249491.25 -1.42895924352578 -1.9029 -0.973 2069727 Maybridge1_000657 Cc1cc(C)c(NC(=O)CSc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F20 compound treatment 1004930.0 -129000.0 -0.63 1013300.0 -58100.0 -0.35 894770.0 -217441.25 -1.24539311142696 -1.2833 -0.892 2069728 Maybridge1_000658 COc1cc(/C=C(\C#N)/c2nn(c(c2C#N)n3cccc3)c4ccccc4)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F21 compound treatment 1029820.0 -104000.0 -0.51 983120.0 -88200.0 -0.52 959520.0 -152691.25 -0.874537977155536 -1.1026 -0.9668 2069729 Maybridge1_000659 CCOC(=O)CNC(=O)c1c(OC)cccc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F22 compound treatment 1293930.0 160000.0 0.78 1255920.0 185000.0 1.1 1052480.0 -59731.25 -0.342110281682622 0.8864 0.6381 1547053 Maybridge1_000660 CCOC(=O)c1ccc(OC(=O)c2cccnc2Oc3ccccc3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F23 mock treatment 1157120.0 22800.0 0.11 1120350.0 49000.0 0.29 1110470.0 -1741.25 -0.00997299617838008 0.2268 0.7266 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 F24 mock treatment 1105150.0 -29200.0 -0.14 1009450.0 -61900.0 -0.37 1203840.0 91628.75 0.524802971187218 0.0082 0.0125 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G01 compound treatment 901600.0 -233000.0 -1.14 781880.0 -289000.0 -1.72 849510.0 -262701.25 -1.50461941840957 -2.519 -0.9865 2069730 Maybridge1_000661 Fc1ccc(NC(=S)NNC(=O)c2ccccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G02 compound treatment 1033710.0 -101000.0 -0.49 998750.0 -72600.0 -0.43 1041460.0 -70751.25 -0.405227248164028 -0.767 -0.9967 2069731 Maybridge1_000662 Fc1cccc(/N=C/c2ccc(Cl)c(Cl)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G03 compound treatment 532110.0 -602000.0 -2.94 541180.0 -530000.0 -3.15 479290.0 -632921.25 -3.62505166257892 -5.6119 -0.9961 2069732 Maybridge1_000663 CCOC(=O)CCc1cc(/N=C/c2cc(Br)ccc2O)c(O)c(/N=C/c3cc(Br)ccc3O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G04 compound treatment 940360.0 -194000.0 -0.95 932840.0 -139000.0 -0.82 972100.0 -140111.25 -0.802486122497089 -1.486 -0.9972 2069733 Maybridge1_000664 [O-][N+](=O)c1cc(ccc1N2CCOCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G05 compound treatment 671200.0 -463000.0 -2.26 792450.0 -279000.0 -1.66 719640.0 -392571.25 -2.24844885914825 -3.5621 -0.9908 2069734 Maybridge1_000665 Cc1cc(OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)n(n1)c4ccc(NC(=O)c5c(C)onc5c6c(Cl)cccc6Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G06 compound treatment 849400.0 -285000.0 -1.39 787870.0 -283000.0 -1.69 802160.0 -310051.25 -1.77581618455246 -2.8022 -0.9949 2069735 Maybridge1_000666 COc1cc2CCN=C(c3ccc(cc3)[N+](=O)[O-])c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G07 compound treatment 1042470.0 -91800.0 -0.45 1006080.0 -65300.0 -0.39 1024750.0 -87461.25 -0.50093364652195 -0.7724 -0.9947 1681606 Maybridge1_000667 Cc1nc2cc(Cl)ccc2c(=O)n1c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G08 compound treatment 1278880.0 145000.0 0.71 1060320.0 -11000.0 -0.07 1074500.0 -37711.25 -0.215990898568233 0.2452 0.3307 1649904 Maybridge1_000668 Fc1ccc(NC(=O)c2ccncc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G09 compound treatment 1128380.0 -5940.0 -0.03 1032490.0 -38900.0 -0.23 1070040.0 -42171.25 -0.241535514766697 -0.2896 -0.8632 1446338 Maybridge1_000669 Cc1ccc(NC(=S)Nc2cccc(Cl)c2)cc1NS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G10 compound treatment 1101300.0 -33000.0 -0.16 909350.0 -162000.0 -0.96 1008200.0 -104011.25 -0.595723646092482 -0.9933 -0.8682 2069736 Maybridge1_000670 CC(Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G11 compound treatment 866600.0 -268000.0 -1.31 827370.0 -244000.0 -1.45 823050.0 -289161.25 -1.656168867874 -2.549 -0.9953 2069737 Maybridge1_000671 CC1(C)N/C(=N/c2ccccc2Cl)/SC1=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G12 compound treatment 1003150.0 -131000.0 -0.64 904410.0 -167000.0 -0.99 999560.0 -112651.25 -0.64520918061148 -1.3157 -0.9772 1649200 Maybridge1_000672 Cc1ccc(cc1)C(=O)CC2(O)C(=O)N(CN3CCCCC3)c4ccc(Br)cc42 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G13 compound treatment 1289550.0 155000.0 0.76 1323870.0 253000.0 1.5 1021280.0 -90931.25 -0.520808045223445 1.0041 0.5702 1671135 Maybridge1_000673 CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G14 compound treatment 1289760.0 155000.0 0.76 1247120.0 176000.0 1.05 1163840.0 51628.75 0.295703274340009 1.2126 0.9149 2069738 Maybridge1_000674 COc1cc(CN(C(=O)c2cccc(c2)[N+](=O)[O-])c3cccc(F)c3)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G15 compound treatment 959620.0 -175000.0 -0.85 917240.0 -154000.0 -0.92 859160.0 -253051.25 -1.44934911654518 -1.8587 -0.9704 2069739 Maybridge1_000675 Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G16 compound treatment 1056320.0 -78000.0 -0.38 1024280.0 -47100.0 -0.28 918240.0 -193971.25 -1.11096886430186 -1.0231 -0.8473 2069740 Maybridge1_000676 Fc1cccc(Cl)c1/C=C/2\SC(=S)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G17 compound treatment 1224160.0 89800.0 0.44 1077500.0 6140.0 0.04 1022240.0 -89971.25 -0.515309652499112 -0.023 -0.0339 1057803 Maybridge1_000677 Nc1nc2ccc(Cl)cc2c(c1C#N)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G18 compound treatment 1064270.0 -70000.0 -0.34 1090650.0 19300.0 0.11 843360.0 -268851.25 -1.53984349679983 -1.0204 -0.6452 2069741 Maybridge1_000678 Cc1ccc(cc1[N+](=O)[O-])N2C(=O)CC(SCC(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G19 compound treatment 1124240.0 -10100.0 -0.05 1058460.0 -12900.0 -0.08 1013290.0 -98921.25 -0.566570709668675 -0.3998 -0.6967 2069742 Maybridge1_000679 COc1cccc(/N=C/2\SC(=C)C(C)(C)N2C(=O)C(C3CCCC3)c4ccccc4)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G20 compound treatment 37320.0 -1100000.0 -5.36 36290.0 -1040000.0 -6.16 33010.0 -1079201.25 -6.18111698030323 -10.2168 -0.9979 2069743 Maybridge1_000680 [O-][N+](=O)c1ccc(s1)C2Nc3ccccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G21 compound treatment 791070.0 -343000.0 -1.68 696050.0 -375000.0 -2.23 733690.0 -378521.25 -2.16797759063067 -3.5084 -0.9926 2069744 Maybridge1_000681 COc1cc(CN2CCCN(Cc3cc(OC)c(OC)c(OC)c3)C2c4cc(Br)ccc4O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G22 compound treatment 986560.0 -148000.0 -0.72 1012000.0 -59400.0 -0.35 1010560.0 -101651.25 -0.582206763978497 -0.9567 -0.9641 1014047 Maybridge1_000682 [O-][N+](=O)c1ccc(cc1)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G23 mock treatment 1033600.0 -101000.0 -0.49 1053850.0 -17500.0 -0.1 1054360.0 -57851.25 -0.331342595930803 -0.5355 -0.8891 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 G24 mock treatment 1118160.0 -16200.0 -0.08 1241920.0 171000.0 1.01 1220420.0 108208.75 0.619764795530386 0.8978 0.7537 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H01 compound treatment 915200.0 -219000.0 -1.07 1129920.0 58600.0 0.35 832830.0 -279381.25 -1.60015399199486 -1.3409 -0.6853 2069745 Maybridge1_000683 Cc1onc(c1C(=O)SCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H02 compound treatment 1094200.0 -40100.0 -0.2 923770.0 -148000.0 -0.88 1028240.0 -83971.25 -0.480944697972031 -0.8975 -0.8801 2069746 Maybridge1_000684 COc1cc2CCN(Cc2cc1OC)c3c(cc(cc3[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H03 compound treatment 935200.0 -199000.0 -0.97 919790.0 -152000.0 -0.9 912360.0 -199851.25 -1.1446465197384 -1.7429 -0.9949 1364884 Maybridge1_000685 COc1ccc(CCNC(=O)c2ccccc2N)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H04 compound treatment 1005280.0 -129000.0 -0.63 1071360.0 4.52 0.0 956740.0 -155471.25 -0.890460406086417 -0.8781 -0.8048 2069747 Maybridge1_000686 [O-][N+](=O)c1ccc(cc1)c2cn3nc(sc3n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H05 compound treatment 824690.0 -310000.0 -1.51 788860.0 -282000.0 -1.68 827060.0 -285151.25 -1.63320162326507 -2.7862 -0.999 2069748 Maybridge1_000687 OC(C(=O)NNC(=S)Nc1cc(Cl)ccc1Cl)(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H06 compound treatment 1169640.0 35300.0 0.17 1167300.0 95900.0 0.57 937600.0 -174611.25 -1.00008461102781 -0.1484 -0.1274 2069749 Maybridge1_000688 [O-][N+](=O)c1cc(ccc1Oc2ccc(Cl)cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H07 compound treatment 894150.0 -240000.0 -1.17 1299520.0 228000.0 1.36 816540.0 -295671.25 -1.69345484353589 -0.8718 -0.3534 2069750 Maybridge1_000689 Fc1ccccc1n2c(S)nnc2CCc3nc(no3)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H08 compound treatment 1050320.0 -84000.0 -0.41 1037700.0 -33700.0 -0.2 1012390.0 -99821.25 -0.571725452847737 -0.6826 -0.9329 2069751 Maybridge1_000690 N/C(=N\O)/c1cccc(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H09 compound treatment 998450.0 -136000.0 -0.66 1250200.0 179000.0 1.06 946660.0 -165551.25 -0.948193529691914 -0.3167 -0.2015 2069752 Maybridge1_000691 COc1cc(cc(OC)c1OC)C(=O)NNC(=O)CSc2cc(OC)c(cc2OC)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H10 compound treatment 619560.0 -515000.0 -2.52 653390.0 -418000.0 -2.49 581760.0 -530451.25 -3.03815551418058 -4.6411 -0.9955 2069753 Maybridge1_000692 N/C(=N\OC(=O)c1c(Cl)cccc1Cl)/c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H11 compound treatment 1240800.0 106000.0 0.52 1250720.0 179000.0 1.07 1010620.0 -101591.25 -0.581863114433226 0.5802 0.439 2069754 Maybridge1_000693 [O-][N+](=O)c1cc(c(cc1N2CCCCC2)N3CCCCC3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H12 compound treatment 1505980.0 372000.0 1.82 1288320.0 217000.0 1.29 1315400.0 203188.75 1.16376202569409 2.4652 0.9809 2069755 Maybridge1_000694 CN(NC(=O)C)c1ccc(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H13 compound treatment 1166450.0 32100.0 0.16 1404930.0 334000.0 1.98 1103280.0 -8931.25 -0.051153666686666 1.2064 0.6061 2069756 Maybridge1_000695 Clc1ccc(cc1)c2noc(CCC(=O)NNS(=O)(=O)c3cc(Cl)c(Cl)cc3Cl)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H14 compound treatment 1098080.0 -36200.0 -0.18 1086560.0 15200.0 0.09 901090.0 -211121.25 -1.2091953593251 -0.7481 -0.6105 2069757 Maybridge1_000696 [O-][N+](=O)c1cc(Cl)ccc1Sc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H15 compound treatment 1328320.0 194000.0 0.95 1247970.0 177000.0 1.05 1149150.0 36938.75 0.211566410672871 1.2758 0.8918 1295661 Maybridge1_000697 Cc1cccnc1N2C(=O)C3C4CC(C=C4)C3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H16 compound treatment 1080240.0 -54100.0 -0.26 1022960.0 -48400.0 -0.29 979570.0 -132641.25 -0.759701754110872 -0.7573 -0.8865 2069758 Maybridge1_000698 CC(C)(C)c1ccc(OS(=O)(=O)c2ccc(Oc3c(Cl)cccc3[N+](=O)[O-])cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H17 compound treatment 1506740.0 372000.0 1.82 1302400.0 231000.0 1.37 1228650.0 116438.75 0.6669020581567 2.2288 0.9382 2069759 Maybridge1_000699 Cc1nc2c(Br)cc(Br)cc2c(=O)n1c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H18 compound treatment 890630.0 -244000.0 -1.19 741600.0 -330000.0 -1.96 705080.0 -407131.25 -2.33184114880063 -3.1658 -0.9678 2069760 Maybridge1_000700 Nc1cc(ccc1Oc2ccc(C#N)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H19 compound treatment 748490.0 -386000.0 -1.89 741150.0 -330000.0 -1.96 743040.0 -369171.25 -2.11442553649263 -3.4428 -0.9989 2069761 Maybridge1_000701 [O-][N+](=O)c1ccc(cc1)/C(=C/c2c(F)cccc2Cl)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H20 compound treatment 1240870.0 107000.0 0.52 1143170.0 71800.0 0.43 1087900.0 -24311.25 -0.139242500124418 0.4667 0.6788 2069762 Maybridge1_000702 Clc1ccc(/C=C(\C#N)/c2nn(c(c2C#N)n3cccc3)c4ccccc4)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H21 compound treatment 1146770.0 12500.0 0.06 1132200.0 60800.0 0.36 1039070.0 -73141.25 -0.418915955050649 0.0022 0.0039 2069763 Maybridge1_000703 O=C1CCC(=O)N(N1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H22 compound treatment 1376640.0 242000.0 1.18 1114080.0 42700.0 0.25 1304480.0 192268.75 1.1012178084548 1.466 0.8957 2069764 Maybridge1_000704 O=C(NNC(=O)c1cccnc1Oc2ccccc2)c3cccnc3Oc4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H23 mock treatment 1292380.0 158000.0 0.77 1076740.0 5380.0 0.03 1253200.0 140988.75 0.807511997096675 0.9306 0.8325 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 H24 mock treatment 1203430.0 69100.0 0.34 1115360.0 44000.0 0.26 1277120.0 164908.75 0.944513615811306 0.8913 0.8599 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I01 compound treatment 806400.0 -328000.0 -1.6 779900.0 -291000.0 -1.73 847420.0 -264791.25 -1.51658987756984 -2.8012 -0.9985 2069765 Maybridge1_000705 COc1cccc(NC(=S)NNC(=O)c2ccccc2Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I02 compound treatment 611860.0 -522000.0 -2.55 534820.0 -537000.0 -3.19 595440.0 -516771.25 -2.95980341785884 -5.0247 -0.9959 1339133 Maybridge1_000706 Cc1ccc(cc1)S(=O)(=O)N2CN3CCN(C3)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I03 compound treatment 546290.0 -588000.0 -2.87 548850.0 -523000.0 -3.11 505120.0 -607091.25 -3.47711053333983 -5.4601 -0.9969 2069766 Maybridge1_000707 CCOC(=O)CCc1cc(/N=C/c2cc(Cl)cc(Cl)c2O)c(O)c(/N=C/c3cc(Cl)cc(Cl)c3O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I04 compound treatment 665340.0 -469000.0 -2.29 565280.0 -506000.0 -3.01 723150.0 -389061.25 -2.22834536074991 -4.3469 -0.9902 2069767 Maybridge1_000708 Oc1c(Cl)cc(Cl)cc1/C=N/c2cc(ccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I05 compound treatment 1030000.0 -104000.0 -0.51 1030250.0 -41100.0 -0.24 929790.0 -182421.25 -1.04481632683722 -1.0386 -0.8743 2069768 Maybridge1_000709 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2ccccc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I06 compound treatment 1267740.0 133000.0 0.65 1211210.0 140000.0 0.83 1070880.0 -41331.25 -0.236724421132905 0.7198 0.6647 1491155 Maybridge1_000710 COc1ccc(CCNC(=O)c2c(C)onc2c3ccccc3Cl)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I07 compound treatment 806510.0 -328000.0 -1.6 755290.0 -316000.0 -1.88 777670.0 -334541.25 -1.91608247394716 -3.1161 -0.997 2069769 Maybridge1_000711 COc1cc(/C=N/N=C/c2cc(Br)ccc2O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I08 compound treatment 1231000.0 96700.0 0.47 1036070.0 -35300.0 -0.21 1045340.0 -66871.25 -0.383004577569849 -0.0695 -0.1081 2069770 Maybridge1_000712 C/C=C(\C)/c1nc2c(Br)cc(Br)cc2c(=O)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I09 compound treatment 1346240.0 212000.0 1.04 1418430.0 347000.0 2.06 1245920.0 133708.75 0.765815852270482 2.2315 0.9173 1127116 Maybridge1_000713 Cc1ccc(NC(=S)Nc2ccccc2Cl)cc1NS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I10 compound treatment 648990.0 -485000.0 -2.37 673000.0 -398000.0 -2.37 659370.0 -452841.25 -2.59364482737278 -4.2341 -0.9991 2069771 Maybridge1_000714 Nc1cc(ccc1NCCc2ccccn2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I11 compound treatment 430810.0 -704000.0 -3.44 393890.0 -677000.0 -4.03 464600.0 -647611.25 -3.70918852624606 -6.4519 -0.9979 2069772 Maybridge1_000715 Cc1cc(C)c(/N=C\2/NC(C)(C)C(=C)S2)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I12 compound treatment 806130.0 -328000.0 -1.6 639840.0 -432000.0 -2.57 604060.0 -508151.25 -2.91043243318826 -4.0876 -0.9736 2069773 Maybridge1_000716 Oc1ccc(Br)cc1/C=N/c2cc(ccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I13 compound treatment 1250090.0 116000.0 0.57 829960.0 -241000.0 -1.44 1036290.0 -75921.25 -0.43483838398153 -0.7533 -0.4699 2069774 Maybridge1_000717 COc1ccc(NC(=S)NC(=O)c2ccccc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I14 compound treatment 619370.0 -515000.0 -2.52 620610.0 -451000.0 -2.68 518400.0 -593811.25 -3.40104943398656 -4.9637 -0.9911 1116212 Maybridge1_000718 C(Cc1ccncc1)c2c[nH]c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I15 compound treatment 883310.0 -251000.0 -1.23 859310.0 -212000.0 -1.26 776800.0 -335411.25 -1.92106539235359 -2.5452 -0.9771 2069775 Maybridge1_000719 CCOC(=O)c1ccc(NC(=O)CSc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I16 compound treatment 969240.0 -165000.0 -0.81 968060.0 -103000.0 -0.61 789540.0 -322671.25 -1.84809713890775 -1.8873 -0.8953 2069776 Maybridge1_000720 Fc1cccc(Cl)c1C=C2C(=O)NC(=S)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I17 compound treatment 965920.0 -168000.0 -0.82 970720.0 -101000.0 -0.6 1065230.0 -46981.25 -0.269084753312574 -0.9759 -0.9273 1949968 Maybridge1_000721 Fc1cccc(F)c1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I18 compound treatment 942190.0 -192000.0 -0.94 1054480.0 -16900.0 -0.1 964540.0 -147671.25 -0.845785965201211 -1.0882 -0.8585 2069777 Maybridge1_000722 CN1C(NC(=O)c2ccccc12)c3ccc(s3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I19 compound treatment 862570.0 -272000.0 -1.33 845250.0 -226000.0 -1.34 858480.0 -253731.25 -1.45324381139159 -2.3819 -0.9992 2069778 Maybridge1_000723 Cc1ccc(NC(=O)c2ccccc2[N+](=O)[O-])c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I20 compound treatment 224340.0 -910000.0 -4.45 170470.0 -901000.0 -5.36 147490.0 -964721.25 -5.52543364792652 -8.85 -0.9957 2069779 Maybridge1_000724 [O-][N+](=O)c1csc(c1)C2Nc3ccccc3N2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I21 compound treatment 745650.0 -389000.0 -1.9 639280.0 -432000.0 -2.57 655540.0 -456671.25 -2.6155811233459 -4.0899 -0.9905 2069780 Maybridge1_000725 COc1cc(cc(OC)c1OC)C2OC(=NN2C(=O)C)c3cc(C)ccc3[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I22 compound treatment 1169790.0 35500.0 0.17 1176980.0 106000.0 0.63 982490.0 -129721.25 -0.742977476241026 0.0337 0.0341 2069781 Maybridge1_000726 Fc1cccc(F)c1C(=O)Nc2nnc(s2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I23 mock treatment 1071460.0 -62900.0 -0.31 1132860.0 61500.0 0.37 1106770.0 -5441.25 -0.0311647181367469 0.0159 0.0331 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 I24 mock treatment 1090800.0 -43500.0 -0.21 1143150.0 71800.0 0.43 1191680.0 79468.75 0.455156663345667 0.3865 0.5863 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J01 compound treatment 816170.0 -318000.0 -1.55 861480.0 -210000.0 -1.25 757320.0 -354891.25 -2.03263694471818 -2.7915 -0.9805 2069782 Maybridge1_000727 FC(F)(F)c1cc(NC(=O)CSC(=O)c2c(Cl)cccc2Cl)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J02 compound treatment 1182450.0 48100.0 0.24 878720.0 -193000.0 -1.15 1075740.0 -36471.25 -0.20888880796597 -0.6462 -0.544 1367065 Maybridge1_000728 Cc1ccc2nc(NC(=O)C(C)(C)C)nc(O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J03 compound treatment 1358440.0 224000.0 1.1 1372510.0 301000.0 1.79 1252750.0 140538.75 0.804934625507143 2.1309 0.9478 2069783 Maybridge1_000729 Nc1nn(cc1C#N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J04 compound treatment 1151110.0 16800.0 0.08 1192050.0 121000.0 0.72 1012990.0 -99221.25 -0.568288957395029 0.1336 0.1454 2069784 Maybridge1_000730 CC(C)(C)NNC(=O)c1ccccc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J05 compound treatment 782580.0 -352000.0 -1.72 711040.0 -360000.0 -2.14 709640.0 -402571.25 -2.30572378336005 -3.5605 -0.9928 2069785 Maybridge1_000731 OC(C(=O)NNC(=S)Nc1ccc(F)cc1)(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J06 compound treatment 1105300.0 -29000.0 -0.14 1153460.0 82100.0 0.49 924960.0 -187251.25 -1.07248011523153 -0.4192 -0.3532 2069786 Maybridge1_000732 ClC(Cl)C(=O)Nc1cccc(C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J07 compound treatment 1072330.0 -62000.0 -0.3 1010350.0 -61000.0 -0.36 1014780.0 -97431.25 -0.558036745961117 -0.7065 -0.9661 2069787 Maybridge1_000733 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=O)c2cccc(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J08 compound treatment 1175940.0 41600.0 0.2 1173370.0 102000.0 0.61 1091540.0 -20671.25 -0.118394427711322 0.3993 0.6137 1550932 Maybridge1_000734 Clc1ccc(SCC(=O)Nc2cccc(C#N)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J09 compound treatment 1407840.0 274000.0 1.34 1075590.0 4230.0 0.03 1106800.0 -5411.25 -0.0309928933641115 0.7682 0.5746 2069788 Maybridge1_000735 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNS(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J10 compound treatment 525760.0 -609000.0 -2.97 519810.0 -552000.0 -3.28 523550.0 -588661.25 -3.37155284801748 -5.5568 -0.9986 2069789 Maybridge1_000736 N/C(=N\OC(=O)c1sc2ccccc2c1Cl)/c3cccc(c3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J11 compound treatment 1354050.0 220000.0 1.07 1218320.0 147000.0 0.87 1066320.0 -45891.25 -0.262841786573487 0.9726 0.6903 2069790 Maybridge1_000737 CSC1=NC(C)(C)CCC(C)(C)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J12 compound treatment 1039380.0 -94900.0 -0.46 1053710.0 -17600.0 -0.1 1036800.0 -75411.25 -0.431917362846728 -0.5778 -0.8993 2069791 Maybridge1_000738 CN(NC(=O)C)c1ccc(cc1NC(=O)c2sc3ccccc3c2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J13 compound treatment 1436410.0 302000.0 1.48 1273890.0 203000.0 1.2 1371840.0 259628.75 1.4870216979455 2.406 0.9956 2069792 Maybridge1_000739 Cc1ccc(cc1)S(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J14 compound treatment 1064420.0 -69900.0 -0.34 976270.0 -95100.0 -0.57 912160.0 -200051.25 -1.14579201822263 -1.1851 -0.8961 1073582 Maybridge1_000740 [O-][N+](=O)c1cc(Cl)ccc1S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J15 compound treatment 1318570.0 184000.0 0.9 1150940.0 79600.0 0.47 1133320.0 21108.75 0.120900205645588 0.8628 0.8424 1272417 Maybridge1_000741 Cc1cccc(n1)N2C(=O)C3C4CC(C=C4)C3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J16 compound treatment 720680.0 -414000.0 -2.02 705710.0 -366000.0 -2.17 627470.0 -484741.25 -2.77635183560843 -4.0251 -0.9903 1535750 Maybridge1_000742 Nc1cccc(Cl)c1Oc2ccc(cc2)S(=O)(=O)Nc3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J17 compound treatment 556640.0 -578000.0 -2.82 617340.0 -454000.0 -2.7 602800.0 -509411.25 -2.91764907363895 -4.8728 -0.9995 2069793 Maybridge1_000743 C/C(=N\N=C1NCCN1)/c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J18 compound treatment 1325650.0 191000.0 0.93 1063700.0 -7660.0 -0.05 1188880.0 76668.75 0.439119684566362 0.767 0.7419 1727927 Maybridge1_000744 OC(=O)c1cccnc1Oc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J19 compound treatment 892540.0 -242000.0 -1.18 963210.0 -108000.0 -0.64 871240.0 -240971.25 -1.38016100809733 -1.8501 -0.96 2069794 Maybridge1_000745 Cc1ccc(cc1)/C(=C/c2cccs2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J20 compound treatment 1209220.0 74900.0 0.37 1151520.0 80200.0 0.48 1107760.0 -4451.25 -0.0254945006397785 0.4718 0.7843 2069795 Maybridge1_000746 [O-][N+](=O)c1cc(ccc1Sc2nnc(c3cccs3)n2c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J21 compound treatment 797810.0 -337000.0 -1.64 866790.0 -205000.0 -1.22 830760.0 -281451.25 -1.6120099013067 -2.5822 -0.9916 2069796 Maybridge1_000747 CCN(CC)C(=S)Oc1c(Br)cc(Br)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J22 compound treatment 1307040.0 173000.0 0.84 981080.0 -90300.0 -0.54 1263290.0 151078.75 0.865302395626383 0.6769 0.5118 2069797 Maybridge1_000748 CSC1=NCN(CN1)C(C)(C)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J23 mock treatment 1331170.0 197000.0 0.96 1093350.0 22000.0 0.13 1291520.0 179308.75 1.0269895066763 1.2237 0.866 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 J24 mock treatment 1225800.0 91500.0 0.45 1141450.0 70100.0 0.42 1106680.0 -5531.25 -0.0316801924546532 0.4804 0.785 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K01 compound treatment 1022300.0 -112000.0 -0.55 984720.0 -86600.0 -0.52 1023300.0 -88911.25 -0.509238510532661 -0.9074 -0.9995 1285576 Maybridge1_000749 O=c1oc2ccccc2cc1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K02 compound treatment 579840.0 -554000.0 -2.71 596800.0 -475000.0 -2.82 587040.0 -525171.25 -3.00791435419675 -4.93 -0.9991 2069798 Maybridge1_000750 FC(F)(F)c1cc(NC(=O)C(C2CCCC2)c3ccccc3)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K03 compound treatment 1079360.0 -55000.0 -0.27 1204720.0 133000.0 0.79 1130800.0 18588.75 0.106466924744214 0.3643 0.4316 1505255 Maybridge1_000751 CCN(Cc1cc(OC)c(OC)c(OC)c1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K04 compound treatment 861150.0 -273000.0 -1.33 820440.0 -251000.0 -1.49 813440.0 -298771.25 -1.71121007004154 -2.62 -0.9948 2069799 Maybridge1_000752 Nc1cc(ccc1N2CCCCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K05 compound treatment 1295790.0 161000.0 0.79 1112800.0 41400.0 0.25 1340670.0 228458.75 1.30849575917731 1.3532 0.8744 1366214 Maybridge1_000753 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K06 compound treatment 1222430.0 88100.0 0.43 1139460.0 68100.0 0.4 1209280.0 97068.75 0.555960529958439 0.8034 0.99 1452426 Maybridge1_000754 COc1ccc(CCNC(=O)c2c(C)onc2c3ccccc3)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K07 compound treatment 1455040.0 321000.0 1.57 1137720.0 66400.0 0.39 1300250.0 188038.75 1.0769905155132 1.7544 0.9034 2069800 Maybridge1_000755 CCOC(=O)c1ccc(/N=C/c2cc(Cl)cc(Cl)c2O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K08 compound treatment 1447210.0 313000.0 1.53 1249090.0 178000.0 1.06 1353950.0 241738.75 1.38455685853058 2.2922 0.9891 1462342 Maybridge1_000756 Cc1onc(c1C(=O)Nc2ccc3OCOCc3c2)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K09 compound treatment 1140560.0 6240.0 0.03 1189920.0 119000.0 0.71 1195410.0 83198.75 0.476520210076669 0.6998 0.8218 1525441 Maybridge1_000757 COc1ccc(NC(=S)Nc2ccc(C)c(NS(=O)(=O)C)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K10 compound treatment 1346940.0 213000.0 1.04 1335940.0 265000.0 1.57 1160240.0 48028.75 0.27508430162376 1.667 0.8749 1633514 Maybridge1_000758 CCOC(=O)c1cnc2c(Cl)cc(Br)cc2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K11 compound treatment 1158320.0 24000.0 0.12 925940.0 -145000.0 -0.86 1205920.0 93708.75 0.536716155423273 -0.1217 -0.1188 2069801 Maybridge1_000759 Cc1cc2CSC(SCc2cc1C)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K12 compound treatment 1439840.0 306000.0 1.49 1393140.0 322000.0 1.91 1326660.0 214448.75 1.22825359035657 2.6757 0.9837 2069802 Maybridge1_000760 CCC(C(=O)NNC(=O)c1ccc(cc1)N(C)C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K13 compound treatment 643290.0 -491000.0 -2.4 776030.0 -295000.0 -1.76 632480.0 -479731.25 -2.74765709857832 -3.9854 -0.9844 2069803 Maybridge1_000761 Clc1cccc(Nc2nc3ccccc3s2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K14 compound treatment 1412530.0 278000.0 1.36 1321480.0 250000.0 1.49 1132610.0 20398.75 0.11683368602655 1.711 0.8477 1035571 Maybridge1_000762 OC(=O)CCc1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K15 compound treatment 1222500.0 88200.0 0.43 1080750.0 9390.0 0.06 1047150.0 -65061.25 -0.372637816287512 0.0659 0.1151 1004900 Maybridge1_000763 CC(=O)Nc1ccccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K16 compound treatment 1208110.0 73800.0 0.36 1260640.0 189000.0 1.13 1018830.0 -93381.25 -0.534840401655337 0.5492 0.4234 2069804 Maybridge1_000764 Cc1nc2ccc(Br)cc2c(=O)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K17 compound treatment 1069920.0 -64400.0 -0.31 1133150.0 61800.0 0.37 1049670.0 -62541.25 -0.358204535386138 -0.1763 -0.2929 2069805 Maybridge1_000765 Fc1cccc(F)c1C(=O)Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K18 compound treatment 234590.0 -900000.0 -4.4 201870.0 -869000.0 -5.17 212800.0 -899411.25 -5.15137111789924 -8.4973 -0.9973 2069806 Maybridge1_000766 [O-][N+](=O)c1cc(ccc1SCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K19 compound treatment 200960.0 -933000.0 -4.56 193490.0 -878000.0 -5.22 204580.0 -907631.25 -5.19845110560134 -8.6481 -0.9981 2069807 Maybridge1_000767 FC(F)(F)c1cc(Nc2nc3ccccc3s2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K20 compound treatment 33830.0 -1100000.0 -5.38 34980.0 -1040000.0 -6.16 29840.0 -1082371.25 -6.19927313127837 -10.2416 -0.9979 2069808 Maybridge1_000768 [O-][N+](=O)c1ccc(s1)C2Nc3cc(ccc3O2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K21 compound treatment 1051650.0 -82700.0 -0.4 1329920.0 259000.0 1.54 1020530.0 -91681.25 -0.52510366453933 0.3514 0.2099 2069809 Maybridge1_000769 Cc1ccc(cc1)S(=O)(=O)NNC(=S)NCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K22 compound treatment 767070.0 -367000.0 -1.79 908250.0 -163000.0 -0.97 819890.0 -292321.25 -1.67426774392493 -2.5626 -0.9711 2069810 Maybridge1_000770 Cc1ccc(NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K23 mock treatment 1135530.0 1210.0 0.01 1094090.0 22700.0 0.14 1131970.0 19758.75 0.113168090876995 0.1468 0.8322 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 K24 mock treatment 1292580.0 158000.0 0.77 1167520.0 96200.0 0.57 1305280.0 193068.75 1.10579980239174 1.415 0.9656 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L01 compound treatment 1025950.0 -108000.0 -0.53 1068080.0 -3280.0 -0.02 971520.0 -140691.25 -0.805808068101373 -0.7822 -0.8111 1379387 Maybridge1_000771 Cc1nc2ccc(Br)cc2c(=O)n1c3ccccc3N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L02 compound treatment 1355430.0 221000.0 1.08 1038270.0 -33100.0 -0.2 1315800.0 203588.75 1.16605302266256 1.1834 0.7388 2069811 Maybridge1_000772 FC(F)(F)c1ccc(Cl)c(c1)C(=O)NNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L03 compound treatment 1148480.0 14200.0 0.07 973890.0 -97500.0 -0.58 1071940.0 -40271.25 -0.230653279166454 -0.4278 -0.6817 2069812 Maybridge1_000773 CCOC(=O)CCc1nc(no1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L04 compound treatment 996680.0 -138000.0 -0.67 865440.0 -206000.0 -1.22 869660.0 -242551.25 -1.38921044612279 -1.8973 -0.963 2069813 Maybridge1_000774 Fc1cccc(Cl)c1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L05 compound treatment 1135930.0 1610.0 0.01 1020570.0 -50800.0 -0.3 955360.0 -156851.25 -0.898364345627646 -0.6885 -0.7264 2069814 Maybridge1_000775 Clc1cccc(c1)n2ncc(C#N)c2n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L06 compound treatment 1343050.0 209000.0 1.02 1270800.0 199000.0 1.19 1243040.0 130828.75 0.749320674097483 1.7062 0.9837 2069815 Maybridge1_000776 Clc1cccc(Cl)c1C(=O)Nc2ccc(C#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L07 compound treatment 1412170.0 278000.0 1.36 1082670.0 11300.0 0.07 1288420.0 176208.75 1.00923428017064 1.4053 0.8301 2069816 Maybridge1_000777 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=O)c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L08 compound treatment 1158300.0 24000.0 0.12 1093560.0 22200.0 0.13 1138500.0 26288.75 0.150568616387302 0.2308 0.9948 1037133 Maybridge1_000778 [O-][N+](=O)c1cc(ccc1Oc2ccccc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L09 compound treatment 1106920.0 -27400.0 -0.13 950350.0 -121000.0 -0.72 835290.0 -276921.25 -1.58606436063876 -1.4084 -0.8063 2069817 Maybridge1_000779 Oc1ccc(CCC(=O)NNC(=S)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L10 compound treatment 1355150.0 221000.0 1.08 1008130.0 -63200.0 -0.38 1383360.0 271148.75 1.55300241063749 1.3025 0.6756 2069818 Maybridge1_000780 N/C(=N\OC(=O)c1ccc(cc1)[N+](=O)[O-])/c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L11 compound treatment 1219600.0 85300.0 0.42 1203240.0 132000.0 0.78 1219360.0 107148.75 0.613693653563935 1.0477 0.9705 2069819 Maybridge1_000781 CCOC(=O)C1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L12 compound treatment 1020320.0 -114000.0 -0.56 959610.0 -112000.0 -0.66 1037680.0 -74531.25 -0.426877169516089 -0.9517 -0.9847 2069820 Maybridge1_000782 Cc1cc(OC(=O)c2cccs2)c(Cl)c(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L13 compound treatment 1224880.0 90600.0 0.44 1185480.0 114000.0 0.68 1189350.0 77138.75 0.441811606004317 0.9024 0.9779 2069821 Maybridge1_000783 Cc1ccc(cc1)S(=O)(=O)c2ccccc2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L14 compound treatment 1032270.0 -102000.0 -0.5 1266570.0 195000.0 1.16 936960.0 -175251.25 -1.00375020617736 -0.1972 -0.1222 2069822 Maybridge1_000784 OC(=O)c1ccccc1C(=O)c2ccc(Sc3ccc(Cl)cc3)c(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L15 compound treatment 1112380.0 -21900.0 -0.11 1175900.0 105000.0 0.62 1139270.0 27058.75 0.154978785551611 0.3865 0.595 1632645 Maybridge1_000785 Cc1cc(C)nc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L16 compound treatment 308800.0 -826000.0 -4.03 235360.0 -836000.0 -4.97 320010.0 -792201.25 -4.53732665542451 -7.8185 -0.9964 2090 Maybridge1_000786 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L17 compound treatment 1037400.0 -96900.0 -0.47 922050.0 -149000.0 -0.89 854720.0 -257491.25 -1.47477918289522 -1.6375 -0.9172 2069823 Maybridge1_000787 C/C(=N\N=C1NCCN1)/c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L18 compound treatment 1497950.0 364000.0 1.78 1387360.0 316000.0 1.88 1453400.0 341188.75 1.95415597981696 3.2389 0.9992 2069824 Maybridge1_000788 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(Cl)cc2Sc3cc(Cl)ccc3OS(=O)(=O)c4ccc(C)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L19 compound treatment 1309920.0 176000.0 0.86 1363810.0 292000.0 1.74 1282080.0 169868.75 0.97292197822036 2.0611 0.95 2069825 Maybridge1_000789 COc1cc(CCC(=O)NNC(=S)Nc2ccc(F)cc2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L20 compound treatment 1044600.0 -89700.0 -0.44 1171640.0 100000.0 0.6 983250.0 -128961.25 -0.738624582000929 -0.3352 -0.3206 1250861 Maybridge1_000790 Fc1ccc(NC(=O)c2cccnc2Oc3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L21 compound treatment 900000.0 -234000.0 -1.14 850780.0 -221000.0 -1.31 799950.0 -312261.25 -1.78847394280327 -2.4508 -0.9819 2069826 Maybridge1_000791 CCN(CC)C(=S)Oc1c(C)cc(C)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L22 compound treatment 956520.0 -178000.0 -0.87 973450.0 -97900.0 -0.58 1030480.0 -81731.25 -0.468115114948587 -1.1079 -0.967 1032648 Maybridge1_000792 CC(=O)COc1ccc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L23 mock treatment 1131760.0 -2560.0 -0.01 1109790.0 38400.0 0.23 1082470.0 -29741.25 -0.170342783971427 0.0264 0.0925 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 L24 mock treatment 1349330.0 215000.0 1.05 1051760.0 -19600.0 -0.12 1240530.0 128318.75 0.734944668120321 0.9636 0.7485 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M01 compound treatment 370270.0 -764000.0 -3.73 374690.0 -697000.0 -4.14 349200.0 -763011.25 -4.37014115165026 -7.0702 -0.9979 1921024 Maybridge1_000793 FC(F)(F)c1cccc(NC(=O)c2ccc(Cl)cc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M02 compound treatment 1201560.0 67200.0 0.33 1072220.0 865.0 0.01 1114420.0 2208.75 0.0126505988852818 0.2 0.6081 2069827 Maybridge1_000794 [O-][N+](=O)c1ccc(cc1)C(=O)N(c2nc3ccccc3s2)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M03 compound treatment 796210.0 -338000.0 -1.65 845980.0 -225000.0 -1.34 774510.0 -337701.25 -1.93418134999809 -2.8442 -0.9893 2069828 Maybridge1_000795 CN(C)c1ccc(/C=N/N=C(\C(=O)c2ccccc2)/c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M04 compound treatment 777990.0 -356000.0 -1.74 886160.0 -185000.0 -1.1 740900.0 -371311.25 -2.12668237027396 -2.8688 -0.9689 2069829 Maybridge1_000796 Oc1c(Cl)cc(Cl)cc1/C=N/c2cc(ccc2N3CCOCC3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M05 compound treatment 980480.0 -154000.0 -0.75 1125190.0 53800.0 0.32 897770.0 -214441.25 -1.22821063416342 -0.9582 -0.6496 1365502 Maybridge1_000797 Cc1onc(c1C(=O)Oc2cc(C)nc3ccc(F)cc23)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M06 compound treatment 1255850.0 122000.0 0.59 1258150.0 187000.0 1.11 1267930.0 155718.75 0.891877960460659 1.4991 0.9713 2069830 Maybridge1_000798 FC(F)(F)c1ccc(N2CCCCC2)c(NC(=O)c3sc4ccccc4c3Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M07 compound treatment 1436000.0 302000.0 1.47 1344130.0 273000.0 1.62 1384650.0 272438.75 1.56039087586082 2.6884 0.9992 1668985 Maybridge1_000799 CCOC(=O)c1ccc(cc1)N2CC3CCCCN3C2c4ccc(Cl)c(Cl)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M08 compound treatment 1134830.0 513.0 0.0 1115170.0 43800.0 0.26 1080130.0 -32081.25 -0.183745116236988 0.0458 0.1436 2069831 Maybridge1_000800 [O-][N+](=O)c1cc(ccc1NCc2ccccc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M09 compound treatment 1361550.0 227000.0 1.11 1421280.0 350000.0 2.08 1403140.0 290928.75 1.66629221072844 2.8044 0.9711 1516323 Maybridge1_000801 COc1ccccc1NC(=S)Nc2ccc(C)c(NS(=O)(=O)C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M10 compound treatment 1442130.0 308000.0 1.5 1432390.0 361000.0 2.15 1326720.0 214508.75 1.22859723990185 2.8171 0.9731 2069832 Maybridge1_000802 FC(F)(F)c1cc(NC=C2C(=O)NC(=O)NC2=O)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M11 compound treatment 1422130.0 288000.0 1.41 1430820.0 359000.0 2.14 1263650.0 151438.75 0.867364292898008 2.5468 0.9427 2069833 Maybridge1_000803 Cc1cc2CSC(SCc2cc1C)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M12 compound treatment 1010880.0 -123000.0 -0.6 838240.0 -233000.0 -1.39 888080.0 -224131.25 -1.28371003572465 -1.8897 -0.9528 2069834 Maybridge1_000804 Cc1c(Cl)cccc1NC(=S)Nc2cc3c(c([N+](=O)[O-])c2C)C(C)(C)CC3(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M13 compound treatment 1277660.0 143000.0 0.7 1311060.0 240000.0 1.43 1144160.0 31948.75 0.182986223491182 1.333 0.8338 2069835 Maybridge1_000805 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(C)cc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M14 compound treatment 1192970.0 58700.0 0.29 1013950.0 -57400.0 -0.34 1179090.0 66878.75 0.383047533763007 0.1895 0.3225 2069836 Maybridge1_000806 CCOC(=O)c1ccc(cc1)S(=O)(=O)NNC(=O)c2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M15 compound treatment 646000.0 -488000.0 -2.39 636800.0 -435000.0 -2.58 596180.0 -516031.25 -2.95556507346716 -4.5758 -0.996 2069837 Maybridge1_000807 Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(/N=C/c3cc(Cl)cc(Cl)c3O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M16 compound treatment 1332180.0 198000.0 0.97 1399910.0 329000.0 1.95 1336500.0 224288.75 1.28461211578099 2.4278 0.9595 1716824 Maybridge1_000808 COc1ccc(OC)c(CCC(=O)O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M17 compound treatment 1171760.0 37400.0 0.18 1211740.0 140000.0 0.83 1154950.0 42738.75 0.244785866715717 0.7289 0.82 2069838 Maybridge1_000809 Cc1cc(/N=C/2\SC(=C)C(C)(C)N2C(=O)c3c(F)cccc3F)cc(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M18 compound treatment 878410.0 -256000.0 -1.25 871570.0 -200000.0 -1.19 881000.0 -231211.25 -1.32426068206661 -2.1723 -0.999 2069839 Maybridge1_000810 COc1cc(/C=C(\C#N)/c2ccc(cc2)[N+](=O)[O-])cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M19 compound treatment 875230.0 -259000.0 -1.27 840080.0 -231000.0 -1.38 889070.0 -223141.25 -1.27803981822768 -2.2627 -0.9993 2069840 Maybridge1_000811 Cc1ccc(NC(=O)c2ccccc2/N=C/c3cc(Cl)cc(Cl)c3O)c(/N=C/c4cc(Cl)cc(Cl)c4O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M20 compound treatment 909950.0 -224000.0 -1.1 984800.0 -86600.0 -0.51 965680.0 -146531.25 -0.839256623841066 -1.4146 -0.9601 2069841 Maybridge1_000812 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M21 compound treatment 1303870.0 170000.0 0.83 1353790.0 282000.0 1.68 1293330.0 181118.75 1.03735626795864 2.0469 0.9561 2069842 Maybridge1_000813 COCCCNC(=S)NNS(=O)(=O)c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M22 compound treatment 1205980.0 71700.0 0.35 1382630.0 311000.0 1.85 1026270.0 -85941.25 -0.492227858041756 0.9866 0.5067 2069843 Maybridge1_000814 [O-][N+](=O)c1ccc(cc1)C2N(Cc3ccccc3)CCC4CCCCN24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M23 mock treatment 1110350.0 -24000.0 -0.12 1127740.0 56400.0 0.34 1086610.0 -25601.25 -0.14663096534774 0.0413 0.1075 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 M24 mock treatment 1184870.0 50600.0 0.25 1004960.0 -66400.0 -0.39 1181020.0 68808.75 0.394101594135885 0.1422 0.2331 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N01 compound treatment 634830.0 -499000.0 -2.44 580190.0 -491000.0 -2.92 519810.0 -592401.25 -3.3929736696727 -5.0542 -0.9912 2069844 Maybridge1_000815 COc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N02 compound treatment 1130470.0 -3850.0 -0.02 1037120.0 -34200.0 -0.2 1060020.0 -52191.25 -0.298924988826923 -0.301 -0.8311 1531991 Maybridge1_000816 COc1cc2CCN=C(c3ccccc3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N03 compound treatment 1256510.0 122000.0 0.6 1277210.0 206000.0 1.22 1199360.0 87148.75 0.499143805140331 1.3396 0.9235 1510864 Maybridge1_000817 CC(NC(=O)c1ccccc1N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N04 compound treatment 964590.0 -170000.0 -0.83 987700.0 -83700.0 -0.5 60890.0 -1051321.25 -6.02143449160073 -4.2425 -0.6956 1610286 Maybridge1_000818 Cc1ccc2nc(oc(=O)c2c1)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N05 compound treatment 1080710.0 -53600.0 -0.26 993440.0 -77900.0 -0.46 972160.0 -140051.25 -0.802142472951818 -0.8818 -0.916 2069845 Maybridge1_000819 Cc1cccc(c1)C(=O)NNC(=O)CCc2nc(no2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N06 compound treatment 1277690.0 143000.0 0.7 1302740.0 231000.0 1.38 1217130.0 104918.75 0.600921345464704 1.5458 0.933 1684490 Maybridge1_000820 Fc1cccc(F)c1C(=O)Nc2cccc(C#N)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N07 compound treatment 1286320.0 152000.0 0.74 1208540.0 137000.0 0.82 1237570.0 125358.75 0.717991290553627 1.3143 0.9985 2069846 Maybridge1_000821 [O-][N+](=O)c1cc(ccc1NNc2ccc(cc2[N+](=O)[O-])C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N08 compound treatment 922850.0 -211000.0 -1.03 932800.0 -139000.0 -0.82 837540.0 -274671.25 -1.5731775026911 -1.9805 -0.9639 1471855 Maybridge1_000822 CN(C)c1ccc(cc1N)c2n[nH]c(=O)c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N09 compound treatment 1275270.0 141000.0 0.69 1222670.0 151000.0 0.9 1259060.0 146848.75 0.841075102684791 1.4027 0.994 2069847 Maybridge1_000823 CNC(=S)NNC(=O)c1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N10 compound treatment 1107740.0 -26600.0 -0.13 1032320.0 -39000.0 -0.23 997310.0 -114901.25 -0.658096038559135 -0.5889 -0.8297 1933421 Maybridge1_000824 N/C(=N\OC(=O)c1cccs1)/c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N11 compound treatment 762520.0 -372000.0 -1.82 805700.0 -266000.0 -1.58 783000.0 -329211.25 -1.88555493934227 -3.0495 -0.9972 1430952 Maybridge1_000825 Clc1ccc(cc1)c2noc(CCC(=O)Nc3cccc(Cl)c3Cl)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N12 compound treatment 1299170.0 165000.0 0.81 1429150.0 358000.0 2.13 1365280.0 253068.75 1.44944934766256 2.5303 0.938 2069848 Maybridge1_000826 Cc1cc(OC(=O)C(C2CCCC2)c3ccccc3)c(Cl)c(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N13 compound treatment 1190820.0 56500.0 0.28 1110340.0 39000.0 0.23 1074160.0 -38051.25 -0.217938245991434 0.1674 0.3974 2069849 Maybridge1_000827 FC(F)(F)c1ccccc1S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N14 compound treatment 1268080.0 134000.0 0.65 1259920.0 189000.0 1.12 1224320.0 112108.75 0.642102015972989 1.3954 0.9637 2069850 Maybridge1_000828 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])C(=O)c3ccccc3C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N15 compound treatment 1227910.0 93600.0 0.46 1066360.0 -5000.0 -0.03 1189000.0 76788.75 0.439806983656904 0.5008 0.7884 2069851 Maybridge1_000829 FC(F)(F)c1cc(cc(c1)S(=O)(=O)c2ccc(Br)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N16 compound treatment 957170.0 -177000.0 -0.87 974240.0 -97100.0 -0.58 893620.0 -218591.25 -1.25197972771131 -1.556 -0.9558 2069852 Maybridge1_000830 C/C(=N\O)/c1ccc(Cl)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N17 compound treatment 938730.0 -196000.0 -0.96 961660.0 -110000.0 -0.65 949780.0 -162431.25 -0.930323753337832 -1.4655 -0.9871 2069853 Maybridge1_000831 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N18 compound treatment 864040.0 -270000.0 -1.32 974990.0 -96400.0 -0.57 824070.0 -288141.25 -1.6503268256044 -2.0461 -0.9343 2069854 Maybridge1_000832 Cc1cc(ccc1Cl)C2=CSC3=NCCN23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N19 compound treatment 1193120.0 58800.0 0.29 1154330.0 83000.0 0.49 1198680.0 86468.75 0.495249110293928 0.7367 0.9747 1241971 Maybridge1_000833 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N20 compound treatment 1205540.0 71200.0 0.35 1118800.0 47400.0 0.28 1160640.0 48428.75 0.277375298592232 0.5239 0.9944 2069855 Maybridge1_000834 FC(F)(F)c1ccc(N2CCOCC2)c(NC(=O)c3cccnc3Oc4ccccc4)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N21 compound treatment 1284390.0 150000.0 0.73 1328680.0 257000.0 1.53 1270190.0 157978.75 0.904822093332527 1.8292 0.9512 1314785 Maybridge1_000835 O=C(Nc1ccccc1N2CCOCC2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N22 compound treatment 1155520.0 21200.0 0.1 1156230.0 84900.0 0.5 1161140.0 48928.75 0.280239044802822 0.513 0.8747 2069856 Maybridge1_000836 COc1cc(/C=N/NS(=O)(=O)c2ccc(C)cc2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N23 mock treatment 1279360.0 145000.0 0.71 1271440.0 200000.0 1.19 1305120.0 192908.75 1.10488340360435 1.734 0.9788 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 N24 mock treatment 1141860.0 7540.0 0.04 1067110.0 -4250.0 -0.03 1092480.0 -19731.25 -0.113010584835412 -0.0585 -0.4818 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O01 compound treatment 1014560.0 -120000.0 -0.59 1074400.0 3040.0 0.02 944960.0 -167251.25 -0.95793026680792 -0.8804 -0.7842 1345387 Maybridge1_000837 OC(=O)c1cc2cc(Br)ccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O02 compound treatment 1197890.0 63600.0 0.31 1136130.0 64800.0 0.39 1003720.0 -108491.25 -0.62138281213937 0.043 0.0541 2069857 Maybridge1_000838 COc1cc(cc(OC)c1OC)C2NC(=O)c3cc(ccc3N2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O03 compound treatment 1203330.0 69000.0 0.34 1134370.0 63000.0 0.37 1162130.0 49918.75 0.285909262299791 0.5761 0.9941 2069858 Maybridge1_000839 O=C(/C(=N\N=C\c1cccs1)/c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O04 compound treatment 1222490.0 88200.0 0.43 1305880.0 235000.0 1.39 1129140.0 16928.75 0.0969592873250549 1.1099 0.7587 1315297 Maybridge1_000840 COc1ccc(CCNC(=O)c2ccccc2Cl)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O05 compound treatment 405720.0 -729000.0 -3.56 406800.0 -665000.0 -3.95 405730.0 -706481.25 -4.04636600508094 -6.673 -0.9985 2069859 Maybridge1_000841 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3OCOCc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O06 compound treatment 702880.0 -431000.0 -2.11 726080.0 -345000.0 -2.05 760290.0 -351921.25 -2.01562629222727 -3.5662 -0.9998 2069860 Maybridge1_000842 FC(F)(F)c1ccc(N2CCCC2)c(NC=C(C#N)C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O07 compound treatment 945450.0 -189000.0 -0.92 881440.0 -190000.0 -1.13 921120.0 -191091.25 -1.09447368612886 -1.8167 -0.9963 1573890 Maybridge1_000843 CCOC(=O)c1ccc(cc1)N2CC3CCCCN3C2c4cccc(OC)c4O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O08 compound treatment 718840.0 -415000.0 -2.03 728960.0 -342000.0 -2.04 686400.0 -425811.25 -2.43883070722828 -3.7556 -0.9961 1949137 Maybridge1_000844 CCOC(=O)C(=CNc1ccccc1F)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O09 compound treatment 514740.0 -620000.0 -3.03 490910.0 -580000.0 -3.45 474090.0 -638121.25 -3.65483462316906 -5.8507 -0.997 1130032 Maybridge1_000845 Cc1c(Cl)cccc1NC(=S)Nc2ccc(Cl)cc2C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O10 compound treatment 413050.0 -721000.0 -3.52 362150.0 -709000.0 -4.22 344610.0 -767601.25 -4.39643034186347 -7.0077 -0.9957 2069861 Maybridge1_000846 FC(F)(F)c1cc(NC=C(C#N)C#N)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O11 compound treatment 916360.0 -218000.0 -1.06 774140.0 -297000.0 -1.77 830020.0 -282191.25 -1.61624824569838 -2.5684 -0.9799 2069862 Maybridge1_000847 CN(C)c1ccc(cc1)C2SCc3cc(C)c(C)cc3CS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O12 compound treatment 857610.0 -277000.0 -1.35 809700.0 -262000.0 -1.56 896200.0 -216011.25 -1.23720279726467 -2.3932 -0.9955 2069863 Maybridge1_000848 Clc1ccc(cc1)C2CN3C(=N2)C=Cc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O13 compound treatment 624550.0 -510000.0 -2.49 828120.0 -243000.0 -1.45 626770.0 -485441.25 -2.78036108030326 -3.8783 -0.9688 2069864 Maybridge1_000849 CC1(C)N/C(=N\c2cccc(c2)C(F)(F)F)/SC1=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O14 compound treatment 974240.0 -160000.0 -0.78 837850.0 -234000.0 -1.39 939450.0 -172761.25 -0.989488750048623 -1.8245 -0.9726 1186960 Maybridge1_000850 Cc1ccc(cc1)S(=O)(=O)NN2C(Nc3ccccc3C2=O)c4cc(Cl)cc(Cl)c4O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O15 compound treatment 1235890.0 102000.0 0.5 991050.0 -80300.0 -0.48 1222720.0 110508.75 0.632938028099101 0.3762 0.4022 1932406 Maybridge1_000851 FC(F)(F)c1ccccc1NC(=O)c2cc3ccccc3oc2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O16 compound treatment 1109280.0 -25000.0 -0.12 1112410.0 41100.0 0.24 1125560.0 13348.75 0.0764548644572296 0.1145 0.4037 2069865 Maybridge1_000852 [O-][N+](=O)c1ccc(C=C2C(=O)NC(=O)NC2=O)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O17 compound treatment 1339530.0 205000.0 1.0 1151210.0 79900.0 0.47 1243950.0 131738.75 0.754532692200757 1.2887 0.9605 1041620 Maybridge1_000853 OC(=O)C(C1CCCC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O18 compound treatment 1330040.0 196000.0 0.96 1170800.0 99400.0 0.59 1217970.0 105758.75 0.605732439098495 1.2432 0.9735 2069866 Maybridge1_000854 CN(C)c1ccc(/C=C(\C#N)/c2ccc(cc2)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O19 compound treatment 44380.0 -1090000.0 -5.33 41200.0 -1030000.0 -6.13 39370.0 -1072841.25 -6.14469012850453 -10.159 -0.9979 2069867 Maybridge1_000855 FC(F)(F)c1cc(NCCC2CCCCN2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O20 compound treatment 813090.0 -321000.0 -1.57 713310.0 -358000.0 -2.13 745920.0 -366291.25 -2.09793035831963 -3.3466 -0.9913 2069868 Maybridge1_000856 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O21 compound treatment 1129920.0 -4400.0 -0.02 1208930.0 138000.0 0.82 1116210.0 3998.75 0.0229028103191945 0.4731 0.5779 2069869 Maybridge1_000857 FC(F)(F)c1cc(NC(=S)N2CCCCC2CCN3CCOCC3)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O22 compound treatment 1266190.0 132000.0 0.64 1303810.0 232000.0 1.38 1301300.0 189088.75 1.08300438255544 1.7953 0.9598 2069870 Maybridge1_000858 CC(=O)Nc1ccc(Br)cc1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O23 mock treatment 1335620.0 201000.0 0.98 1290370.0 219000.0 1.3 1232200.0 119988.75 0.68723465625189 1.7165 0.9693 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 O24 mock treatment 989120.0 -145000.0 -0.71 981760.0 -89600.0 -0.53 1050080.0 -62131.25 -0.355856263493454 -0.9226 -0.9652 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P01 compound treatment 949280.0 -185000.0 -0.9 1050130.0 -21200.0 -0.13 833860.0 -278351.25 -1.59425467480104 -1.5153 -0.8248 2069871 Maybridge1_000859 CCOC(=O)C(=CNNS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P02 compound treatment 1010720.0 -124000.0 -0.6 1106290.0 34900.0 0.21 945480.0 -166731.25 -0.954951970748907 -0.7801 -0.679 1214041 Maybridge1_000860 Cc1onc(c1C(=O)Nc2cccc3cccnc23)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P03 compound treatment 1256510.0 122000.0 0.6 1126770.0 55400.0 0.33 1132400.0 20188.75 0.115630912618102 0.6017 0.8699 809283 Maybridge1_000861 NC(=O)c1cnn(c1N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P04 compound treatment 825470.0 -309000.0 -1.51 817820.0 -254000.0 -1.51 782350.0 -329861.25 -1.88927780941604 -2.8324 -0.994 2069872 Maybridge1_000862 ClC(Cl)(Cl)C(=O)Nc1cccc2cccnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P05 compound treatment 1272900.0 139000.0 0.68 1300740.0 229000.0 1.36 1050680.0 -61531.25 -0.352419768040746 0.975 0.6237 2069873 Maybridge1_000863 OC(c1nnc(S)n1c2ccc(F)cc2)(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P06 compound treatment 1201940.0 67600.0 0.33 1132480.0 61100.0 0.36 1040500.0 -71711.25 -0.410725640888361 0.1635 0.2553 2069874 Maybridge1_000864 Cc1onc(c1C(=O)Nc2cccc(C#N)c2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P07 compound treatment 724750.0 -410000.0 -2.0 767000.0 -304000.0 -1.81 744210.0 -368001.25 -2.10772437035985 -3.4171 -0.9981 2069875 Maybridge1_000865 CC(=O)c1c(O)nc2ccc(Cl)cc2c1c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P08 compound treatment 1028130.0 -106000.0 -0.52 938400.0 -133000.0 -0.79 941290.0 -170921.25 -0.978950163993652 -1.3212 -0.9707 2069876 Maybridge1_000866 Cc1cccc(C)c1NC(=O)CSc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P09 compound treatment 1067230.0 -67100.0 -0.33 1127940.0 56600.0 0.34 959260.0 -152951.25 -0.876027125185043 -0.5007 -0.5038 2069877 Maybridge1_000867 COc1cc([N+](=O)[O-])c(OC)cc1SCc2nnc(o2)c3ccccc3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P10 compound treatment 791710.0 -343000.0 -1.67 742170.0 -329000.0 -1.96 741230.0 -370981.25 -2.12479229777497 -3.3234 -0.9953 2069878 Maybridge1_000868 [O-][N+](=O)c1ccc(N2CCCCC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P11 compound treatment 1152270.0 18000.0 0.09 1067570.0 -3790.0 -0.02 1006950.0 -105261.25 -0.602883011618958 -0.3104 -0.5092 2069879 Maybridge1_000869 CCOC(=O)C1CCN(CC1)c2ccc(cc2N)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P12 compound treatment 1187100.0 52800.0 0.26 1028440.0 -42900.0 -0.26 1150630.0 38418.75 0.220043099456218 0.1286 0.3031 2069880 Maybridge1_000870 CN(NC(=O)c1ccncc1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P13 compound treatment 926890.0 -207000.0 -1.01 989380.0 -82000.0 -0.49 991000.0 -121211.25 -0.694236515736782 -1.2674 -0.959 2069881 Maybridge1_000871 FC(F)(F)c1ccccc1S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P14 compound treatment 1202900.0 68600.0 0.34 1148450.0 77100.0 0.46 1109030.0 -3181.25 -0.0182205852648796 0.4476 0.7879 2069882 Maybridge1_000872 Clc1ccc(SC(C(=O)c2ccc(Cl)cc2)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P15 compound treatment 981800.0 -153000.0 -0.75 939390.0 -132000.0 -0.78 878370.0 -233841.25 -1.33932398713431 -1.6566 -0.9621 2069883 Maybridge1_000873 Fc1ccccc1NC(=O)CSc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P16 compound treatment 979170.0 -155000.0 -0.76 827330.0 -244000.0 -1.45 959840.0 -152371.25 -0.872705179580758 -1.7793 -0.9591 2069884 Maybridge1_000874 COc1ccc(NC(=S)NCCSc2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P17 compound treatment 813150.0 -321000.0 -1.57 827320.0 -244000.0 -1.45 821620.0 -290591.25 -1.66435918203629 -2.7047 -0.9984 2069885 Maybridge1_000875 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P18 compound treatment 713940.0 -420000.0 -2.05 622050.0 -449000.0 -2.67 627840.0 -484371.25 -2.7742326634126 -4.3301 -0.992 2069886 Maybridge1_000876 N/C(=N\O)/c1ccc(OCc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P19 compound treatment 1342310.0 208000.0 1.02 1171330.0 100000.0 0.59 1226010.0 113798.75 0.651781478164784 1.3063 0.9707 2069887 Maybridge1_000877 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)CCc2cc(OC)c(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P20 compound treatment 861660.0 -273000.0 -1.33 824090.0 -247000.0 -1.47 937990.0 -174221.25 -0.997850888983547 -2.1942 -0.988 2069888 Maybridge1_000878 Cc1ccc(SC(=O)c2cccnc2Oc3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P21 compound treatment 1164190.0 29900.0 0.15 1167710.0 96400.0 0.57 1101120.0 -11091.25 -0.0635250503164153 0.3784 0.6363 1389928 Maybridge1_000879 S=C1NCN(CCN2CCCC2)CN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P22 compound treatment 1092850.0 -41500.0 -0.2 1078720.0 7360.0 0.04 1012160.0 -100051.25 -0.573042776104609 -0.4225 -0.6934 2069889 Maybridge1_000880 C/C(=N\O)/COc1ccc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P23 mock treatment 1222650.0 88300.0 0.43 1239680.0 168000.0 1.0 1166090.0 53878.75 0.308590132287664 1.0052 0.8873 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.543 P24 mock treatment 982150.0 -152000.0 -0.74 1073720.0 2360.0 0.01 1073400.0 -38811.25 -0.222291140231531 -0.5495 -0.708 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A01 compound treatment 824320.0 -225000.0 -1.1 902530.0 -213000.0 -1.27 790400.0 -319874.375 -1.83207805854226 -2.4251 -0.9759 2069890 Maybridge1_000881 Clc1cc(Cl)cc(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A02 compound treatment 761630.0 -288000.0 -1.41 921730.0 -194000.0 -1.15 861210.0 -249064.375 -1.42651432019849 -2.3018 -0.9956 2069891 Maybridge1_000882 Fc1cc2[nH]c(S)nc2cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A03 compound treatment 761930.0 -288000.0 -1.41 818830.0 -297000.0 -1.76 781710.0 -328564.375 -1.88184996768232 -2.9172 -0.9929 1488119 Maybridge1_000883 Clc1ccc(cc1)C(=O)CNc2cccc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A04 compound treatment 861560.0 -188000.0 -0.92 914850.0 -201000.0 -1.19 921300.0 -188974.375 -1.08234930060977 -1.8449 -0.9945 1497445 Maybridge1_000884 CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A05 compound treatment 910180.0 -140000.0 -0.68 924230.0 -191000.0 -1.14 919240.0 -191034.375 -1.0941479349974 -1.6823 -0.9784 1022907 Maybridge1_000885 CC(=O)c1cc2ccccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A06 compound treatment 835290.0 -214000.0 -1.05 909400.0 -206000.0 -1.23 829860.0 -280414.375 -1.60607120760249 -2.2401 -0.9842 2069892 Maybridge1_000886 [O-][N+](=O)c1ccc(Oc2ccccc2F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A07 compound treatment 747490.0 -302000.0 -1.48 778460.0 -337000.0 -2.0 756220.0 -354054.375 -2.0278437494982 -3.1808 -0.9905 1472485 Maybridge1_000887 Cc1onc(c1C(=O)Nc2ccc(Br)cn2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A08 compound treatment 896490.0 -153000.0 -0.75 917190.0 -198000.0 -1.18 817980.0 -292294.375 -1.67411381756611 -2.08 -0.9538 2069893 Maybridge1_000888 [O-][N+](=O)c1cc(Cl)ccc1Oc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A09 compound treatment 879430.0 -170000.0 -0.83 916210.0 -199000.0 -1.19 907200.0 -203074.375 -1.16310694374841 -1.8364 -0.9886 1619653 Maybridge1_000889 CC(=O)Nc1ccc(CC(C#N)C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A10 compound treatment 999040.0 -50700.0 -0.25 999200.0 -116000.0 -0.69 972530.0 -137744.375 -0.788929863872708 -0.9981 -0.9256 1480482 Maybridge1_000890 CC(=O)Nc1c(F)cc(F)cc1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A11 compound treatment 942240.0 -108000.0 -0.53 983380.0 -132000.0 -0.79 945450.0 -164824.375 -0.944030358638269 -1.3021 -0.9746 1657436 Maybridge1_000891 Clc1ccc(Cl)c(NC(=S)NCCc2ccncc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A12 compound treatment 854360.0 -195000.0 -0.95 959740.0 -156000.0 -0.93 935130.0 -175144.375 -1.00313808042485 -1.6653 -0.9995 2069894 Maybridge1_000892 [O-][N+](=O)c1cccnc1Sc2cc(Cl)ccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A13 compound treatment 885960.0 -164000.0 -0.8 1024640.0 -90900.0 -0.54 1013310.0 -96964.375 -0.555362722936978 -1.0948 -0.9827 1208589 Maybridge1_000893 Cc1onc(c1C(=O)NCCc2ccncc2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A14 compound treatment 488640.0 -561000.0 -2.74 487430.0 -628000.0 -3.74 536380.0 -573894.375 -3.28697568337047 -5.6371 -0.9923 2069895 Maybridge1_000894 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)Nc3ccc(F)cc3F)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A15 compound treatment 550920.0 -499000.0 -2.44 584360.0 -531000.0 -3.16 560920.0 -549354.375 -3.1464230193547 -5.0475 -0.9934 2069896 Maybridge1_000895 Clc1ccc2OC(=O)N(C(OC(=O)Nc3ccccc3)c2c1)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A16 compound treatment 795520.0 -254000.0 -1.24 791610.0 -324000.0 -1.93 795110.0 -315164.375 -1.8051015692385 -2.8716 -0.9842 2069897 Maybridge1_000896 Cc1ccccc1C(=O)NCC(=O)c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A17 compound treatment 899100.0 -151000.0 -0.74 976680.0 -139000.0 -0.83 946580.0 -163694.375 -0.937558292202335 -1.4431 -0.9951 2069898 Maybridge1_000897 Clc1ccc(SCc2ccc(cc2)c3nc4ccccc4s3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A18 compound treatment 847880.0 -202000.0 -0.99 979850.0 -136000.0 -0.81 890300.0 -219974.375 -1.25990156566636 -1.7628 -0.9837 1045890 Maybridge1_000898 COc1ccccc1Oc2ccccc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A19 compound treatment 853920.0 -196000.0 -0.96 888760.0 -227000.0 -1.35 895900.0 -214374.375 -1.22782760810775 -2.04 -0.9905 2069899 Maybridge1_000899 CSC1=NCCN1C(=O)c2c(C)onc2c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A20 compound treatment 939210.0 -111000.0 -0.54 1041930.0 -73600.0 -0.44 911840.0 -198434.375 -1.13653137891414 -1.2208 -0.9163 2069900 Maybridge1_000900 CC(C)(C)C(=O)Nc1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A21 compound treatment 895520.0 -154000.0 -0.75 897410.0 -218000.0 -1.3 944480.0 -165794.375 -0.949586026286813 -1.7323 -0.9756 1250979 Maybridge1_000901 O=C(Nc1nccs1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A22 compound treatment 45770.0 -1000000.0 -4.91 33390.0 -1080000.0 -6.44 58050.0 -1052224.375 -6.02660713319361 -10.0269 -0.9938 1244212 Maybridge1_000902 Cn1sc(=O)c2cc(ccc12)S(=O)(=O)NC3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A23 mock treatment 870840.0 -179000.0 -0.87 1031580.0 -84000.0 -0.5 962980.0 -147294.375 -0.843627416494979 -1.2801 -0.9746 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 A24 mock treatment 957120.0 -92600.0 -0.45 861510.0 -254000.0 -1.51 945600.0 -164674.375 -0.943171234775092 -1.6781 -0.9132 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B01 compound treatment 845090.0 -205000.0 -1.0 1016090.0 -99500.0 -0.59 945280.0 -164994.375 -0.945004032349869 -1.4645 -0.9779 1364313 Maybridge1_000903 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B02 compound treatment 881780.0 -168000.0 -0.82 1130530.0 15000.0 0.09 949950.0 -160324.375 -0.918256642742957 -0.9526 -0.7715 2069901 Maybridge1_000904 Cc1cc(NC(=O)c2cccs2)c(cc1C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B03 compound treatment 740380.0 -309000.0 -1.51 812960.0 -303000.0 -1.8 775710.0 -334564.375 -1.9162149222094 -3.0179 -0.9953 2069902 Maybridge1_000905 CSC1=NCCN1CC(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B04 compound treatment 935320.0 -114000.0 -0.56 934260.0 -181000.0 -1.08 958950.0 -151324.375 -0.866709210952335 -1.4457 -0.9689 1571188 Maybridge1_000906 Clc1ccc(Oc2ccccc2NC(=O)c3cccs3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B05 compound treatment 851160.0 -199000.0 -0.97 1003360.0 -112000.0 -0.67 929880.0 -180394.375 -1.03320741563604 -1.542 -0.9843 2069903 Maybridge1_000907 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CCCC3CCN(CC3)S(=O)(=O)c4cc(OC)ccc4OC)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B06 compound treatment 901370.0 -148000.0 -0.72 953890.0 -162000.0 -0.96 957360.0 -152914.375 -0.875815923902012 -1.4793 -0.9935 1632115 Maybridge1_000908 Clc1ccc(Oc2ccccc2NC(=O)NC(=O)c3c(Cl)cccc3Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B07 compound treatment 755420.0 -294000.0 -1.44 784320.0 -331000.0 -1.97 861920.0 -248354.375 -1.42244780057945 -2.7888 -0.9877 2069904 Maybridge1_000909 CN(NC(=O)NC(=O)c1c(Cl)cccc1Cl)c2cccc(F)c2C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B08 compound treatment 875800.0 -174000.0 -0.85 985510.0 -130000.0 -0.77 946730.0 -163544.375 -0.936699168339158 -1.478 -0.997 2069905 Maybridge1_000910 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/c2cc(Br)ccc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B09 compound treatment 793330.0 -256000.0 -1.25 832750.0 -283000.0 -1.68 872710.0 -237564.375 -1.36064815735492 -2.4799 -0.992 2069906 Maybridge1_000911 CSC1=NCCN1CC(=O)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B10 compound treatment 827070.0 -223000.0 -1.09 812680.0 -303000.0 -1.8 892280.0 -217994.375 -1.24856113067242 -2.3889 -0.9763 2069907 Maybridge1_000912 COc1ccc(/C=C/2\SC(=S)NC2=O)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B11 compound treatment 936920.0 -113000.0 -0.55 952430.0 -163000.0 -0.97 911310.0 -198964.375 -1.13956694989736 -1.5363 -0.9633 1295895 Maybridge1_000913 NNC(=O)CNC(=O)c1c(F)cccc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B12 compound treatment 988380.0 -61400.0 -0.3 995950.0 -120000.0 -0.71 1064770.0 -45504.375 -0.260625962943043 -0.7343 -0.9012 2069908 Maybridge1_000914 CN(C)/C=N/c1nnc(s1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B13 compound treatment 787390.0 -262000.0 -1.28 732850.0 -383000.0 -2.28 797120.0 -313154.375 -1.79358930947193 -3.0896 -0.9751 2069909 Maybridge1_000915 Brc1cc(cc(Br)c1n2cccc2)C3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B14 compound treatment 933090.0 -117000.0 -0.57 1011620.0 -104000.0 -0.62 958580.0 -151694.375 -0.868828383148172 -1.1876 -0.9822 1625161 Maybridge1_000916 Cc1ncc(COn2c(nc3ccccc3c2=O)c4ccccc4)c(CO)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B15 compound treatment 783360.0 -266000.0 -1.3 908080.0 -207000.0 -1.23 738120.0 -372154.375 -2.13151136232157 -2.6944 -0.9673 2069910 Maybridge1_000917 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3cccnc3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B16 compound treatment 573790.0 -476000.0 -2.33 602940.0 -513000.0 -3.05 567650.0 -542624.375 -3.10787699536016 -4.8969 -0.9922 2069911 Maybridge1_000918 CC(C)(C)c1csc(Cc2ccc(Cl)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B17 compound treatment 974900.0 -74900.0 -0.37 916120.0 -199000.0 -1.19 949600.0 -160674.375 -0.920261265090371 -1.4272 -0.9237 2069912 Maybridge1_000919 COc1ccc(cc1OC)S(=O)(=O)NNc2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B18 compound treatment 875070.0 -175000.0 -0.85 912360.0 -203000.0 -1.21 879040.0 -231234.375 -1.32439313032885 -1.9551 -0.9846 1708614 Maybridge1_000920 Clc1cccc(Cl)c1C(=O)NC(=O)N2CCc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B19 compound treatment 717030.0 -333000.0 -1.63 780250.0 -335000.0 -1.99 756410.0 -353864.375 -2.02675552593818 -3.2599 -0.9954 2069913 Maybridge1_000921 Cc1ccc(NC(=S)Nc2ccc(C)c(C)c2)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B20 compound treatment 617280.0 -432000.0 -2.11 702150.0 -413000.0 -2.46 617180.0 -493094.375 -2.8241942957391 -4.2699 -0.9931 2069914 Maybridge1_000922 Clc1cccc(NC(=S)NN=C2CCCCCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B21 compound treatment 949090.0 -101000.0 -0.49 891080.0 -224000.0 -1.33 857760.0 -252514.375 -1.44627416905156 -1.8897 -0.9315 1545633 Maybridge1_000923 CC(=O)Nc1cc2cc(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)ccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B22 compound treatment 509290.0 -540000.0 -2.64 537600.0 -578000.0 -3.44 533850.0 -576424.375 -3.30146623919605 -5.415 -0.9939 2069915 Maybridge1_000924 C/C(=N\NC(=S)N)/c1cc2cc(Cl)ccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B23 mock treatment 929550.0 -120000.0 -0.59 1019200.0 -96400.0 -0.57 1044250.0 -66024.375 -0.378154107425662 -0.8883 -0.9831 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 B24 mock treatment 992910.0 -56800.0 -0.28 1024990.0 -90600.0 -0.54 1006470.0 -103804.375 -0.594538771097851 -0.8146 -0.9595 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C01 compound treatment 956960.0 -92800.0 -0.45 1100010.0 -15600.0 -0.09 1132420.0 22145.625 0.126838899349799 -0.2419 -0.5043 2069916 Maybridge1_000925 Cc1ccc(cc1)n2nnc(n2)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C02 compound treatment 649990.0 -400000.0 -1.95 687490.0 -428000.0 -2.55 736820.0 -373454.375 -2.1389571024691 -3.8323 -0.9938 1116479 Maybridge1_000926 On1c(nc2ccccc2c1=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C03 compound treatment 947360.0 -102000.0 -0.5 1017210.0 -98400.0 -0.58 1028870.0 -81404.375 -0.466242940863414 -0.8957 -0.9954 2069917 Maybridge1_000927 COc1ccc(cc1)c2c(C#N)c([nH]c(=O)c2C#N)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C04 compound treatment 464750.0 -585000.0 -2.86 468720.0 -647000.0 -3.85 481640.0 -628634.375 -3.60049861850587 -5.9497 -0.9926 2069918 Maybridge1_000928 CC(C)(C)c1ccc(cc1)C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C05 compound treatment 923960.0 -126000.0 -0.61 1044640.0 -70900.0 -0.42 1118180.0 7905.625 0.045279407272193 -0.5722 -0.7662 1781213 Maybridge1_000929 CC(=O)Nc1cc2cc(ccc2oc1=O)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C06 compound treatment 892820.0 -157000.0 -0.77 890630.0 -225000.0 -1.34 939140.0 -171134.375 -0.980170835815916 -1.7809 -0.9748 2069919 Maybridge1_000930 N#Cc1ccccc1N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C07 compound treatment 901540.0 -148000.0 -0.72 949210.0 -166000.0 -0.99 969090.0 -141184.375 -0.808632437801568 -1.4561 -0.9915 1019504 Maybridge1_000931 CCC(=O)c1ccc(cc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C08 compound treatment 882560.0 -167000.0 -0.82 882400.0 -233000.0 -1.39 966960.0 -143314.375 -0.820831996658682 -1.7461 -0.9665 2069920 Maybridge1_000932 [O-][N+](=O)c1cc(ccc1Oc2c(Cl)cccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C09 compound treatment 954570.0 -95200.0 -0.47 991310.0 -124000.0 -0.74 1011470.0 -98804.375 -0.56590130899195 -1.0218 -0.9821 2069921 Maybridge1_000933 [O-][N+](=O)c1ccc2oc(=O)c(NC(=O)c3c(F)cccc3F)cc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C10 compound treatment 749950.0 -300000.0 -1.46 725790.0 -390000.0 -2.32 885250.0 -225024.375 -1.28882540239332 -2.928 -0.9664 2069922 Maybridge1_000934 CC(C)(C)NC(=S)N/N=C/c1ccccc1SC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C11 compound treatment 919000.0 -131000.0 -0.64 1092800.0 -22800.0 -0.14 949120.0 -161154.375 -0.923010461452537 -0.9799 -0.8667 1708697 Maybridge1_000935 Cc1ccc(cc1)S(=O)(=O)NCCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C12 compound treatment 858830.0 -191000.0 -0.93 958300.0 -157000.0 -0.94 821600.0 -288674.375 -1.65338029500144 -2.0331 -0.9607 2069923 Maybridge1_000936 Cc1ccc(Sc2ncccc2[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C13 compound treatment 1079520.0 29800.0 0.15 990170.0 -125000.0 -0.75 1120850.0 10575.625 0.0605718120367442 -0.3116 -0.4088 2069924 Maybridge1_000937 CCOC(=O)CNC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C14 compound treatment 895570.0 -154000.0 -0.75 916860.0 -199000.0 -1.18 887130.0 -223144.375 -1.2780577166415 -1.855 -0.9781 1019893 Maybridge1_000938 NCC(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C15 compound treatment 894400.0 -155000.0 -0.76 957940.0 -158000.0 -0.94 949960.0 -160314.375 -0.918199367818746 -1.5095 -0.9958 2069925 Maybridge1_000939 Cc1nn(c(C)c1N=Nc2cc(Cl)cc(Cl)c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C16 compound treatment 109890.0 -940000.0 -4.59 104050.0 -1010000.0 -6.02 115840.0 -994434.375 -5.6956153461736 -9.4124 -0.9938 2069926 Maybridge1_000940 C/C(=N\NC(=S)NC(C)(C)C)/c1cc(F)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C17 compound treatment 598040.0 -452000.0 -2.21 663310.0 -452000.0 -2.69 624960.0 -485314.375 -2.77963440470232 -4.4317 -0.9952 1556471 Maybridge1_000941 Clc1cccc(N2CCCCC2)c1C(C#N)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C18 compound treatment 870360.0 -179000.0 -0.88 973500.0 -142000.0 -0.84 975540.0 -134734.375 -0.771690111684955 -1.4393 -0.9986 2069927 Maybridge1_000942 NC(=S)NNC(=O)c1ccccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C19 compound treatment 877490.0 -172000.0 -0.84 1048360.0 -67200.0 -0.4 939110.0 -171164.375 -0.980342660588551 -1.2827 -0.9484 2069928 Maybridge1_000943 CSC1=NCCN1C(=O)c2c(C)onc2c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C20 compound treatment 869310.0 -180000.0 -0.88 1034910.0 -80700.0 -0.48 1028510.0 -81764.375 -0.468304838135038 -1.0563 -0.9537 2069929 Maybridge1_000944 CC(C)(C)C(=O)Nc1ccc(F)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C21 compound treatment 1045160.0 -4590.0 -0.02 1148320.0 32800.0 0.19 1156860.0 46585.625 0.266818814123444 0.2535 0.7657 2069930 Maybridge1_000945 Cc1onc(c1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-])c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C22 compound treatment 570570.0 -479000.0 -2.34 573720.0 -542000.0 -3.22 570560.0 -539714.375 -3.09120999241453 -4.9967 -0.9911 2069931 Maybridge1_000946 Fc1cccc(Cl)c1CSC2=NCN(CN2)C3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C23 mock treatment 987560.0 -62200.0 -0.3 1094080.0 -21500.0 -0.13 1086040.0 -24234.375 -0.13880219914454 -0.3293 -0.9208 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 C24 mock treatment 944260.0 -105000.0 -0.52 1075440.0 -40100.0 -0.24 941730.0 -168544.375 -0.965336630445059 -0.9927 -0.8863 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D01 compound treatment 589000.0 -461000.0 -2.25 662080.0 -453000.0 -2.7 668350.0 -441924.375 -2.53111850854731 -4.318 -0.9973 2069932 Maybridge1_000947 COc1cc2CCN(C(C)c2cc1OC)C(=O)Nc3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D02 compound treatment 1005310.0 -44400.0 -0.22 1058770.0 -56800.0 -0.34 1063970.0 -46304.375 -0.265207956879987 -0.4735 -0.9839 2069933 Maybridge1_000948 COC(OC)C(C)NC(=O)NC(=O)c1ccccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D03 compound treatment 945690.0 -104000.0 -0.51 1068740.0 -46800.0 -0.28 1064970.0 -45304.375 -0.259480464458807 -0.6041 -0.9512 2069934 Maybridge1_000949 COC(=O)/C=C/1\Nc2ccccc2C(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D04 compound treatment 1013370.0 -36400.0 -0.18 1072420.0 -43100.0 -0.26 1175250.0 64975.625 0.372147399748949 -0.0359 -0.0739 1544141 Maybridge1_000950 Fc1cccc(F)c1C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D05 compound treatment 859520.0 -190000.0 -0.93 1032120.0 -83400.0 -0.5 952160.0 -158114.375 -0.905598884492149 -1.346 -0.9688 2069935 Maybridge1_000951 Clc1ccccc1C(=O)NC(=O)Nc2cccc(C#C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D06 compound treatment 942150.0 -108000.0 -0.53 1288540.0 173000.0 1.03 1025850.0 -84424.375 -0.483539967975378 0.0112 0.0089 1494826 Maybridge1_000952 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D07 compound treatment 682290.0 -367000.0 -1.8 698720.0 -417000.0 -2.48 679360.0 -430914.375 -2.46805881699012 -3.8926 -0.99 2069936 Maybridge1_000953 CN(NC(=O)NC(=O)c1c(Cl)cccc1Cl)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D08 compound treatment 828580.0 -221000.0 -1.08 924450.0 -191000.0 -1.14 837730.0 -272544.375 -1.5609958422478 -2.1813 -0.9858 2069937 Maybridge1_000954 CC(=O)c1cc(Cl)ccc1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D09 compound treatment 786880.0 -263000.0 -1.28 861940.0 -254000.0 -1.51 849530.0 -260744.375 -1.49341143167788 -2.4745 -0.9974 1666692 Maybridge1_000955 Fc1ccc(NC(=O)c2c(F)cccc2NC(=O)c3cccs3)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D10 compound treatment 928390.0 -121000.0 -0.59 930720.0 -185000.0 -1.1 947650.0 -162624.375 -0.931429875311672 -1.5147 -0.9722 2069938 Maybridge1_000956 [O-][N+](=O)c1ccc2oc3ncccc3c(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D11 compound treatment 850590.0 -199000.0 -0.97 945680.0 -170000.0 -1.01 898640.0 -211634.375 -1.21213427887372 -1.8449 -0.9952 2069939 Maybridge1_000957 CCC(C)(OC(=O)NC(=O)c1c(F)cccc1Cl)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D12 compound treatment 976880.0 -72900.0 -0.36 1344380.0 229000.0 1.36 1071280.0 -38994.375 -0.22333998728116 0.4511 0.3167 1099054 Maybridge1_000958 OC(=O)C1CSC(N1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D13 compound treatment 808490.0 -241000.0 -1.18 561150.0 -554000.0 -3.3 853980.0 -256294.375 -1.46792409040362 -3.4315 -0.9039 2069940 Maybridge1_000959 Clc1cc(Br)cc(Cl)c1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D14 compound treatment 512570.0 -537000.0 -2.62 504540.0 -611000.0 -3.63 453630.0 -656644.375 -3.76092568122313 -5.7845 -0.9886 1230634 Maybridge1_000960 Clc1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D15 compound treatment 793950.0 -256000.0 -1.25 862670.0 -253000.0 -1.5 795230.0 -315044.375 -1.80441427014796 -2.6316 -0.9891 2069941 Maybridge1_000961 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccccn3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D16 compound treatment 565250.0 -485000.0 -2.37 592320.0 -523000.0 -3.11 618650.0 -491624.375 -2.81577488187997 -4.7888 -0.9939 1172112 Maybridge1_000962 Cc1onc(c1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4)c5ccccc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D17 compound treatment 843870.0 -206000.0 -1.01 1097410.0 -18200.0 -0.11 936280.0 -173994.375 -0.996551464140491 -1.2185 -0.858 2069942 Maybridge1_000963 COc1ccc(cc1OC)S(=O)(=O)N2CCN(CC2)c3ccc(cc3[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D18 compound treatment 434360.0 -615000.0 -3.01 461120.0 -654000.0 -3.89 426750.0 -683524.375 -3.91488067750445 -6.2431 -0.9932 2069943 Maybridge1_000964 NNC(=S)Nc1cccc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D19 compound treatment 1118240.0 68500.0 0.33 890680.0 -225000.0 -1.34 1100350.0 -9924.375 -0.0568417825974506 -0.6117 -0.4434 1615615 Maybridge1_000965 Clc1ccc(NC(=S)NCCn2ccnc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D20 compound treatment 480260.0 -569000.0 -2.78 517230.0 -598000.0 -3.56 481540.0 -628734.375 -3.60107136774799 -5.7398 -0.9936 2069944 Maybridge1_000966 Cc1ccc(CSc2nc(C(=O)C(F)(F)F)c3ccccn23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D21 compound treatment 730580.0 -319000.0 -1.56 767850.0 -348000.0 -2.07 798990.0 -311284.375 -1.78287889864433 -3.1235 -0.9934 2069945 Maybridge1_000967 CN(C)/C=N/C(=S)Nc1cccc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D22 compound treatment 797390.0 -252000.0 -1.23 876420.0 -239000.0 -1.42 877960.0 -232314.375 -1.33057882214372 -2.3011 -0.9983 2069946 Maybridge1_000968 N/C(=N\O)/CC(=O)Nc1ccc(F)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D23 mock treatment 938260.0 -111000.0 -0.54 987130.0 -128000.0 -0.76 1079540.0 -30734.375 -0.176030899882211 -0.8571 -0.898 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 D24 mock treatment 955640.0 -94100.0 -0.46 1031940.0 -83600.0 -0.5 1042920.0 -67354.375 -0.385771672345831 -0.7753 -0.9947 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E01 compound treatment 966040.0 -83700.0 -0.41 936920.0 -179000.0 -1.06 878370.0 -231904.375 -1.32823055025104 -1.6163 -0.924 2069947 Maybridge1_000969 CC(C)(C)SCC(=O)Nc1cc(ccc1Oc2ccc(C#N)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E02 compound treatment 765310.0 -284000.0 -1.39 899360.0 -216000.0 -1.29 820040.0 -290234.375 -1.66231518317848 -2.5044 -0.994 2069948 Maybridge1_000970 Fc1ccc(/N=C/c2c(F)cccc2Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E03 compound treatment 1022750.0 -27000.0 -0.13 1214240.0 98700.0 0.59 997500.0 -112774.375 -0.645914378115838 -0.1103 -0.125 2069949 Maybridge1_000971 FC(F)(F)c1cc(NCC(=O)c2ccc(Cl)cc2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E04 compound treatment 918690.0 -131000.0 -0.64 1077680.0 -37900.0 -0.23 973240.0 -137034.375 -0.78486334425367 -0.9529 -0.9183 2069950 Maybridge1_000972 [O-][N+](=O)c1ccc(Oc2ccc(cc2)c3ccccc3)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E05 compound treatment 1012420.0 -37300.0 -0.18 1120020.0 4450.0 0.03 1048650.0 -61624.375 -0.352953140772469 -0.2938 -0.7379 1104647 Maybridge1_000973 Nc1c(C#N)cnn1CCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E06 compound treatment 979930.0 -69800.0 -0.34 1133440.0 17900.0 0.11 966560.0 -143714.375 -0.823122993627154 -0.6108 -0.6807 1104603 Maybridge1_000974 NC(=O)c1ccccc1N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E07 compound treatment 981490.0 -68300.0 -0.33 1270480.0 155000.0 0.92 1004000.0 -106274.375 -0.608685677378166 -0.0121 -0.0105 1106751 Maybridge1_000975 Nc1cc2cc(ccc2oc1=O)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E08 compound treatment 698720.0 -351000.0 -1.72 615220.0 -500000.0 -2.98 695620.0 -414654.375 -2.37492979022173 -4.0792 -0.9769 2069951 Maybridge1_000976 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E09 compound treatment 992850.0 -56900.0 -0.28 1283520.0 168000.0 1.0 1092510.0 -17764.375 -0.101745323179504 0.3574 0.3431 1516140 Maybridge1_000977 CNc1ccccc1C(=O)NCCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E10 compound treatment 1134310.0 84600.0 0.41 1111370.0 -4200.0 -0.02 1142000.0 31725.625 0.181708276744706 0.329 0.7279 1122977 Maybridge1_000978 Cn1[nH]c(=O)c2cnc3c(F)cc(F)cc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E11 compound treatment 1011050.0 -38700.0 -0.19 1153660.0 38100.0 0.23 977380.0 -132894.375 -0.761151525629984 -0.4178 -0.5119 1967118 Maybridge1_000979 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCc2ccncc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E12 compound treatment 724500.0 -325000.0 -1.59 858500.0 -257000.0 -1.53 818240.0 -292034.375 -1.67262466953661 -2.7658 -0.9993 2069952 Maybridge1_000980 [O-][N+](=O)c1cccnc1Sc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E13 compound treatment 1211360.0 162000.0 0.79 1162110.0 46500.0 0.28 1064360.0 -45914.375 -0.262974234835727 0.4638 0.5289 1352645 Maybridge1_000981 N#CC(N1CCOCC1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E14 compound treatment 954820.0 -94900.0 -0.46 1301560.0 186000.0 1.11 1138260.0 27985.625 0.160287455089492 0.4633 0.3829 2069953 Maybridge1_000982 CC1CCN(CC1)S(=O)(=O)c2cc(Cl)c(Oc3ccc(cc3Cl)[N+](=O)[O-])c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E15 compound treatment 909830.0 -140000.0 -0.68 998670.0 -117000.0 -0.7 1035150.0 -75124.375 -0.430274288458402 -1.0445 -0.9801 1411187 Maybridge1_000983 CC(C)(C)NC(=O)NC(=O)c1c(F)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E16 compound treatment 890600.0 -159000.0 -0.78 1078040.0 -37500.0 -0.22 1054780.0 -55494.375 -0.317843612230634 -0.7613 -0.8759 1134663 Maybridge1_000984 Cc1onc(c1C(=O)NCC(=O)c2ccc(Br)cc2)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E17 compound treatment 906940.0 -143000.0 -0.7 825890.0 -290000.0 -1.72 979680.0 -130594.375 -0.747978293061269 -1.8292 -0.9131 2069954 Maybridge1_000985 COC(=O)c1nn(nc1C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E18 compound treatment 521300.0 -528000.0 -2.58 562470.0 -553000.0 -3.29 423600.0 -686674.375 -3.93292227863117 -5.6603 -0.986 2069955 Maybridge1_000986 Fc1ccc(NC(=O)CS(=O)(=O)Cc2ccc(Cl)c(Cl)c2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E19 compound treatment 1060990.0 11200.0 0.05 1087290.0 -28300.0 -0.17 1185130.0 74855.625 0.42873502487021 0.1821 0.3927 2069956 Maybridge1_000987 CSC1=NCCN1C(=O)c2c(C)onc2c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E20 compound treatment 847420.0 -202000.0 -0.99 1022030.0 -93500.0 -0.56 884530.0 -225744.375 -1.29294919693657 -1.6384 -0.9525 2069957 Maybridge1_000988 C/C(=N\O)/c1cc2ccccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E21 compound treatment 904770.0 -145000.0 -0.71 1022190.0 -93400.0 -0.56 966670.0 -143604.375 -0.822492969460824 -1.2044 -0.9878 2069958 Maybridge1_000989 CC(=O)Nc1cc(Sc2ccc(Cl)cc2)c(F)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E22 compound treatment 436800.0 -613000.0 -2.99 642790.0 -473000.0 -2.81 524990.0 -585284.375 -3.35221182204771 -5.2876 -0.9973 2069959 Maybridge1_000990 N#Cc1cccc(CSC2=NCN(CN2)C3CC3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E23 mock treatment 1051380.0 1630.0 0.01 1065830.0 -49700.0 -0.3 1094270.0 -16004.375 -0.0916649365182264 -0.2191 -0.7073 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 E24 mock treatment 1196100.0 146000.0 0.72 1149930.0 34400.0 0.2 1240230.0 129955.625 0.74431985727724 0.9605 0.9129 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F01 compound treatment 991620.0 -58100.0 -0.28 1031930.0 -83600.0 -0.5 1000270.0 -110004.375 -0.630049224109168 -0.8149 -0.957 1593780 Maybridge1_000991 COc1cc2CCN(C(C)c2cc1OC)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F02 compound treatment 913790.0 -136000.0 -0.66 888050.0 -228000.0 -1.35 971240.0 -139034.375 -0.79631832909603 -1.6244 -0.9529 2069960 Maybridge1_000992 Cc1cc(NC(=O)c2ccc(F)cc2)c(cc1C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F03 compound treatment 991640.0 -58100.0 -0.28 993060.0 -123000.0 -0.73 990990.0 -119284.375 -0.683200353777721 -0.979 -0.9428 2069961 Maybridge1_000993 COc1ccccc1Oc2ccc(cc2NC(=O)c3ccc(Cl)cc3Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F04 compound treatment 993310.0 -56400.0 -0.28 1080530.0 -35000.0 -0.21 1114360.0 4085.625 0.0234003862232845 -0.266 -0.7678 2069962 Maybridge1_000994 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F05 compound treatment 989650.0 -60100.0 -0.29 907740.0 -208000.0 -1.24 950100.0 -160174.375 -0.91739751887978 -1.4127 -0.9016 2069963 Maybridge1_000995 Fc1cccc(F)c1C(=O)NC(=O)Nc2cccc(C#C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F06 compound treatment 1215680.0 166000.0 0.81 1197380.0 81800.0 0.49 1234730.0 124455.625 0.712818648960749 1.1605 0.9801 1339372 Maybridge1_000996 Fc1cccc(Cl)c1C(=O)NC(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F07 compound treatment 1142480.0 92700.0 0.45 1087390.0 -28200.0 -0.17 1156750.0 46475.625 0.266188789957115 0.3185 0.5775 2069964 Maybridge1_000997 CN(NC(=O)NC(=O)c1c(Cl)cccc1Cl)c2ccc(Cl)cc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F08 compound treatment 870400.0 -179000.0 -0.88 1015740.0 -99800.0 -0.59 905610.0 -204664.375 -1.17221365669809 -1.5254 -0.9659 2069965 Maybridge1_000998 CC(=O)c1cc(F)cc(Cl)c1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F09 compound treatment 768160.0 -282000.0 -1.38 751320.0 -364000.0 -2.17 754780.0 -355494.375 -2.0360913385847 -3.2204 -0.9831 2069966 Maybridge1_000999 Fc1ccc(NC(=O)c2c(F)cccc2NC(=O)c3cccc(c3)C(F)(F)F)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F10 compound treatment 843360.0 -206000.0 -1.01 867360.0 -248000.0 -1.48 876700.0 -233574.375 -1.33779546259441 -2.2067 -0.9884 2069967 Maybridge1_001000 CCOc1ccc(Br)cc1/C=C/2\SC(=S)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F11 compound treatment 986240.0 -63500.0 -0.31 1022080.0 -93500.0 -0.56 1291380.0 181105.625 1.03728109462061 0.0987 0.0811 2069968 Maybridge1_001001 CCCc1ccc(NC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F12 compound treatment 953620.0 -96100.0 -0.47 1309980.0 194000.0 1.16 909950.0 -200324.375 -1.14735633959017 -0.2661 -0.157 2069969 Maybridge1_001002 COc1cccc2sc(/N=C/N(C)C)nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F13 compound treatment 991220.0 -58500.0 -0.29 998360.0 -117000.0 -0.7 876600.0 -233674.375 -1.33836821183653 -1.3402 -0.8726 2069970 Maybridge1_001003 Brc1ccc(NC(=O)CSc2ccccn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F14 compound treatment 414740.0 -635000.0 -3.1 443520.0 -672000.0 -4.0 534400.0 -575874.375 -3.2983161183644 -6.0029 -0.9939 1281600 Maybridge1_001004 COC(=O)c1ccc(Cl)cc1NC(=O)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F15 compound treatment 846180.0 -204000.0 -0.99 1003730.0 -112000.0 -0.67 836190.0 -274084.375 -1.56981618057642 -1.8645 -0.9446 2069971 Maybridge1_001005 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccncc3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F16 compound treatment 1132640.0 82900.0 0.4 1104800.0 -10800.0 -0.06 1100960.0 -9314.375 -0.0533480122205306 0.166 0.4016 2069972 Maybridge1_001006 Brc1ccc(COc2ccc(cc2)S(=O)(=O)c3ccc(OCc4ccc(Br)cc4)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F17 compound treatment 915740.0 -134000.0 -0.65 974310.0 -141000.0 -0.84 997040.0 -113234.375 -0.64854902462958 -1.2374 -0.9924 2069973 Maybridge1_001007 CN(C)/C=N/C(=S)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F18 compound treatment 446960.0 -603000.0 -2.95 469370.0 -646000.0 -3.84 541630.0 -568644.375 -3.25690634815927 -5.7993 -0.9939 2069974 Maybridge1_001008 NNC(=S)Nc1cc(ccc1Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F19 compound treatment 1130250.0 80500.0 0.39 1135460.0 19900.0 0.12 1221680.0 111405.625 0.638074872864347 0.6638 0.8747 2069975 Maybridge1_001009 Clc1ccc(Cl)c(NC(=S)NCCCn2ccnc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F20 compound treatment 521600.0 -528000.0 -2.58 505760.0 -610000.0 -3.63 504110.0 -606164.375 -3.47180186380195 -5.5879 -0.9899 2069976 Maybridge1_001010 FC(F)(F)c1ccc(Cl)c(NC(=S)NN=C2CCCCCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F21 compound treatment 776180.0 -274000.0 -1.34 866000.0 -250000.0 -1.48 803080.0 -307194.375 -1.7594534546417 -2.6444 -0.9935 2069977 Maybridge1_001011 CSc1cccc(NC(=S)/N=C/N(C)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F22 compound treatment 1007360.0 -42400.0 -0.21 951520.0 -164000.0 -0.98 1102880.0 -7394.375 -0.0423512267718646 -0.7073 -0.7085 2069978 Maybridge1_001012 Clc1ccc(OCOc2ccc(Cl)cc2Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F23 mock treatment 1040380.0 -9370.0 -0.05 1165550.0 50000.0 0.3 1097250.0 -13024.375 -0.0745970091031093 0.1021 0.3295 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 F24 mock treatment 1067520.0 17800.0 0.09 1140350.0 24800.0 0.15 1030130.0 -80144.375 -0.459026300412726 -0.1298 -0.265 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G01 compound treatment 819120.0 -231000.0 -1.13 878820.0 -237000.0 -1.41 913180.0 -197094.375 -1.12885653906975 -2.1151 -0.9942 2069979 Maybridge1_001013 O=c1s[nH]c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G02 compound treatment 873280.0 -176000.0 -0.86 911220.0 -204000.0 -1.22 961280.0 -148994.375 -0.853364153610986 -1.6921 -0.9854 1483646 Maybridge1_001014 Fc1cccc2nc(oc(=O)c12)C(C3CCCC3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G03 compound treatment 1100000.0 50200.0 0.25 1073860.0 -41700.0 -0.25 1132180.0 21905.625 0.125464301168716 0.071 0.1914 1722347 Maybridge1_001015 COc1cc(cc(OC)c1OC)c2c(C#N)c(OC)[nH]c(=O)c2C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G04 compound treatment 870560.0 -179000.0 -0.88 947270.0 -168000.0 -1.0 1011200.0 -99074.375 -0.567447731945668 -1.4109 -0.9759 1136768 Maybridge1_001016 Nc1ccc(Oc2ccc(Cl)cc2Cl)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G05 compound treatment 1100850.0 51100.0 0.25 1219230.0 104000.0 0.62 1138200.0 27925.625 0.159943805544221 0.5924 0.866 2069980 Maybridge1_001017 CC(C)NC(=O)N1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G06 compound treatment 1033280.0 -16500.0 -0.08 1115520.0 -48.7 0.0 1092280.0 -17994.375 -0.103062646436375 -0.1061 -0.8117 2069981 Maybridge1_001018 Cc1ccc(cc1)C(=O)CSC(=S)SC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G07 compound treatment 947850.0 -102000.0 -0.5 973660.0 -142000.0 -0.84 950900.0 -159374.375 -0.912815524942836 -1.3017 -0.972 2069982 Maybridge1_001019 FC(F)(F)c1cc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G08 compound treatment 1232230.0 182000.0 0.89 1254640.0 139000.0 0.83 1037370.0 -72904.375 -0.417559255283382 0.7511 0.5842 2069983 Maybridge1_001020 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)c(Cl)c1Oc3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G09 compound treatment 1083440.0 33700.0 0.16 1219740.0 104000.0 0.62 1148930.0 38655.625 0.221399799223485 0.5805 0.856 1698854 Maybridge1_001021 Fc1cccc(F)c1C(=O)NC(=O)NCCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G10 compound treatment 753500.0 -296000.0 -1.45 815080.0 -300000.0 -1.79 738240.0 -372034.375 -2.13082406323102 -3.0976 -0.988 2069984 Maybridge1_001022 FC(F)(F)c1ccc(OCc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G11 compound treatment 1048860.0 -892.0 0.0 1346990.0 231000.0 1.38 1199060.0 88785.625 0.50851899429725 1.0856 0.74 1033716 Maybridge1_001023 CC(=O)Nc1ccc(F)cc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G12 compound treatment 1125290.0 75500.0 0.37 1215040.0 99500.0 0.59 1117080.0 6805.625 0.0389791656088947 0.5771 0.8264 2069985 Maybridge1_001024 [O-][N+](=O)c1cccnc1Sc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G13 compound treatment 1180130.0 130000.0 0.64 1136910.0 21300.0 0.13 1043900.0 -66374.375 -0.380158729773075 0.2216 0.2944 2069986 Maybridge1_001025 CCOC(=O)CCC(C#N)(N1CCOCC1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G14 compound treatment 1045180.0 -4570.0 -0.02 1222430.0 107000.0 0.64 1279360.0 169085.625 0.968436635718023 0.9131 0.7882 2069987 Maybridge1_001026 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)N3CCCCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G15 compound treatment 1047630.0 -2120.0 -0.01 1130530.0 15000.0 0.09 1027280.0 -82994.375 -0.47534965381309 -0.2291 -0.4735 1716717 Maybridge1_001027 Fc1cccc(Cl)c1C(=O)NC(=O)Nc2ccccc2N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G16 compound treatment 997210.0 -52500.0 -0.26 1141710.0 26100.0 0.16 1059460.0 -50814.375 -0.29103894769951 -0.2265 -0.5418 2069988 Maybridge1_001028 COc1ccccc1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G17 compound treatment 947250.0 -103000.0 -0.5 1145660.0 30100.0 0.18 975040.0 -135234.375 -0.774553857895546 -0.633 -0.6737 2069989 Maybridge1_001029 Cc1nn(nc1C(=O)N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G18 compound treatment 818590.0 -231000.0 -1.13 948760.0 -167000.0 -0.99 929160.0 -181114.375 -1.03733121017929 -1.8237 -0.9985 2069990 Maybridge1_001030 N/C(=N\O)/c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G19 compound treatment 1074300.0 24500.0 0.12 1143170.0 27600.0 0.16 1205490.0 95215.625 0.545346770565439 0.4789 0.8228 2069991 Maybridge1_001031 CSC1=NCCCN1C(=O)c2c(C)onc2c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G20 compound treatment 971760.0 -78000.0 -0.38 1254520.0 139000.0 0.83 1115110.0 4835.625 0.0276960055391697 0.273 0.2999 1190516 Maybridge1_001032 COc1ccc(c2c(C)n[nH]c2C)c(c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G21 compound treatment 942080.0 -108000.0 -0.53 1237920.0 122000.0 0.73 1030120.0 -80154.375 -0.459083575336938 -0.1487 -0.1475 1072508 Maybridge1_001033 Brc1ccc(cc1)C(=O)CSCC(=O)c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G22 compound treatment 289570.0 -760000.0 -3.71 314790.0 -801000.0 -4.76 89690.0 -1020584.375 -5.84538927298746 -8.2685 -0.9838 2069992 Maybridge1_001034 CCC1(CC)N/C(=N/c2cc(Cl)cc(Cl)c2)/SC1=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G23 mock treatment 1009790.0 -40000.0 -0.2 1087730.0 -27800.0 -0.17 1097540.0 -12734.375 -0.072936036300967 -0.2504 -0.9408 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 G24 mock treatment 1185560.0 136000.0 0.66 1158410.0 42800.0 0.25 1150560.0 40285.625 0.230735611870009 0.6634 0.8877 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H01 compound treatment 928610.0 -121000.0 -0.59 995200.0 -120000.0 -0.72 1000960.0 -109314.375 -0.626097254338554 -1.1165 -0.9967 1541940 Maybridge1_001035 COc1ccc(OC)c(c1)S(=O)(=O)N2CCc3cc(OC)c(OC)cc3C2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H02 compound treatment 1149550.0 99800.0 0.49 1284430.0 169000.0 1.0 1184400.0 74125.625 0.424553955402748 1.1064 0.9264 2069993 Maybridge1_001036 Cc1onc(c1C(=O)Nc2cc(C)c(C)cc2[N+](=O)[O-])c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H03 compound treatment 815690.0 -234000.0 -1.14 734930.0 -381000.0 -2.26 837220.0 -273054.375 -1.56391686338261 -2.87 -0.9633 2069994 Maybridge1_001037 COc1ccccc1Oc2ccc(cc2NC(=O)NC(=O)c3ccccc3F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H04 compound treatment 1030080.0 -19700.0 -0.1 1112800.0 -2770.0 -0.02 1047590.0 -62684.375 -0.35902428273892 -0.2723 -0.7319 1249841 Maybridge1_001038 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H05 compound treatment 1078580.0 28800.0 0.14 1197250.0 81700.0 0.49 1106010.0 -4264.375 -0.0244241754935705 0.3477 0.6866 1681763 Maybridge1_001039 Clc1ccccc1C(=O)NC(=O)N2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H06 compound treatment 774680.0 -275000.0 -1.34 755730.0 -360000.0 -2.14 827940.0 -282334.375 -1.61706799305116 -2.945 -0.9817 2069995 Maybridge1_001040 COc1cc(OC)cc(/N=C\2/NC(C)(C)C(=C)S2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H07 compound treatment 1187740.0 138000.0 0.67 1329280.0 214000.0 1.27 1343560.0 233285.625 1.33614164915779 1.8944 0.9649 1713948 Maybridge1_001041 Cc1cc(ccc1Cl)C(=O)CN2C(=O)c3ccccc3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H08 compound treatment 1120860.0 71100.0 0.35 983000.0 -133000.0 -0.79 1112960.0 2685.625 0.0153818968336322 -0.2457 -0.2851 2069996 Maybridge1_001042 CC(=O)c1cc(Br)ccc1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H09 compound treatment 888610.0 -161000.0 -0.79 992640.0 -123000.0 -0.73 1003320.0 -106954.375 -0.612580372224569 -1.2303 -0.9948 2069997 Maybridge1_001043 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2nc(n[nH]2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H10 compound treatment 853760.0 -196000.0 -0.96 890020.0 -226000.0 -1.34 878950.0 -231324.375 -1.32490860464675 -2.0922 -0.9894 2069998 Maybridge1_001044 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H11 compound treatment 815200.0 -235000.0 -1.15 767910.0 -348000.0 -2.07 722150.0 -388124.375 -2.22297941628781 -3.1387 -0.9673 1107935 Maybridge1_001045 CC(=O)Nc1ccc(cc1)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H12 compound treatment 391360.0 -658000.0 -3.22 441890.0 -674000.0 -4.01 376660.0 -733614.375 -4.20177077288137 -6.596 -0.9938 1300335 Maybridge1_001046 Cc1cc(Oc2cc(C)c(Cl)c(C)c2)c3ccccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H13 compound treatment 716740.0 -333000.0 -1.63 803790.0 -312000.0 -1.85 654240.0 -456034.375 -2.61193342661016 -3.5178 -0.9792 2069999 Maybridge1_001047 Clc1ccc(SCC(=O)Nc2ccc(Br)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H14 compound treatment 433820.0 -616000.0 -3.01 476070.0 -639000.0 -3.8 513810.0 -596464.375 -3.4162451873165 -5.9054 -0.9955 1404813 Maybridge1_001048 Fc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H15 compound treatment 883520.0 -166000.0 -0.81 917600.0 -198000.0 -1.18 908060.0 -202214.375 -1.1581813002662 -1.8173 -0.9875 2070000 Maybridge1_001049 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccncc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H16 compound treatment 672220.0 -378000.0 -1.84 800850.0 -315000.0 -1.87 664610.0 -445664.375 -2.55253933020253 -3.6192 -0.9879 1719758 Maybridge1_001050 Clc1cccc(Cl)c1CSc2ncc3ccccn23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H17 compound treatment 1081950.0 32200.0 0.16 1172290.0 56700.0 0.34 1104320.0 -5954.375 -0.034103637685365 0.2659 0.7114 2070001 Maybridge1_001051 [O-][N+](=O)c1cc(ccc1N2CCN(CC2)C(=O)NC(=O)c3ccccc3Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H18 compound treatment 733470.0 -316000.0 -1.55 875470.0 -240000.0 -1.43 778720.0 -331554.375 -1.89897517002165 -2.8129 -0.9925 2070002 Maybridge1_001052 FC(F)(F)C(=O)c1nc(SCc2ccc(Cl)cc2)n3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H19 compound treatment 633820.0 -416000.0 -2.03 684020.0 -432000.0 -2.57 737880.0 -372394.375 -2.13288596050265 -3.8863 -0.9947 2070003 Maybridge1_001053 FC(F)(F)c1cccc(NC(=S)Nc2ccccn2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H20 compound treatment 665120.0 -385000.0 -1.88 672070.0 -443000.0 -2.64 692640.0 -417634.375 -2.39199771763684 -3.9886 -0.9907 2070004 Maybridge1_001054 Cc1ccc(NC(=S)NN=C2CCCCCC2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H21 compound treatment 1043900.0 -5850.0 -0.03 1131410.0 15800.0 0.09 1335910.0 225635.625 1.29232633213577 0.784 0.6049 1593023 Maybridge1_001055 CC(=O)Nc1cc(=O)oc2ccc(NC(=O)c3ccc(F)cc3)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H22 compound treatment 859100.0 -191000.0 -0.93 1111360.0 -4210.0 -0.03 964980.0 -145294.375 -0.832172431652619 -1.0327 -0.8266 2070005 Maybridge1_001056 Cc1cc(OCOc2ccc(Cl)c(C)c2)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H23 mock treatment 1070760.0 21000.0 0.1 1268020.0 152000.0 0.91 1118270.0 7995.625 0.0457948815900992 0.6091 0.6668 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 H24 mock treatment 1037440.0 -12300.0 -0.06 1256600.0 141000.0 0.84 1150600.0 40325.625 0.230964711566856 0.5828 0.6684 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I01 compound treatment 748600.0 -301000.0 -1.47 819750.0 -296000.0 -1.76 806430.0 -303844.375 -1.74026635503074 -2.8699 -0.9969 1094153 Maybridge1_001057 NNC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I02 compound treatment 930720.0 -119000.0 -0.58 1319580.0 204000.0 1.21 1026650.0 -83624.375 -0.478957974038434 0.0881 0.0617 2070006 Maybridge1_001058 Cc1onc(c1c2nc3cccc(F)c3c(=O)o2)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I03 compound treatment 1069130.0 19400.0 0.09 1072640.0 -42900.0 -0.26 1086040.0 -24234.375 -0.13880219914454 -0.1729 -0.5656 2070007 Maybridge1_001059 Cc1cc(=O)cc(C)n1NC(=O)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I04 compound treatment 1002400.0 -47400.0 -0.23 1311300.0 196000.0 1.16 931010.0 -179264.375 -1.02673534920011 -0.0544 -0.0346 1492347 Maybridge1_001060 Nc1ccc(Oc2c(Cl)cccc2Cl)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I05 compound treatment 1043200.0 -6550.0 -0.03 1080640.0 -34900.0 -0.21 1098430.0 -11844.375 -0.0678385680461166 -0.1776 -0.8041 2070008 Maybridge1_001061 Clc1ccc(cc1)C(C#N)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I06 compound treatment 952570.0 -97200.0 -0.47 947570.0 -168000.0 -1.0 973730.0 -136544.375 -0.782056872967292 -1.3024 -0.9615 2070009 Maybridge1_001062 CC(C)(C)SC(=S)SCC(=O)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I07 compound treatment 1031700.0 -18100.0 -0.09 1164640.0 49100.0 0.29 1119590.0 9315.625 0.0533551715860571 0.1484 0.4794 2070010 Maybridge1_001063 Clc1cccc(Cl)c1C(=O)NC(=O)NCc2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I08 compound treatment 898330.0 -151000.0 -0.74 966990.0 -149000.0 -0.88 965280.0 -144994.375 -0.830454183926265 -1.4167 -0.9974 2070011 Maybridge1_001064 CC(C=C)N1C(=O)c2ccccc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I09 compound treatment 1284960.0 235000.0 1.15 1083620.0 -31900.0 -0.19 1265190.0 154915.625 0.887278068109899 1.0661 0.7281 2070012 Maybridge1_001065 [O-][N+](=O)c1ccc(cc1)C(=O)NCCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I10 compound treatment 220320.0 -829000.0 -4.05 309120.0 -806000.0 -4.8 182130.0 -928144.375 -5.31593987357356 -8.1776 -0.994 1648615 Maybridge1_001066 CC1CN(Cc2cc(C)c(O)c(C)c2)CC(C)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I11 compound treatment 1253440.0 204000.0 1.0 1214510.0 98900.0 0.59 1095450.0 -14824.375 -0.0849064954612337 0.8652 0.7464 2070013 Maybridge1_001067 Clc1ccc(SCc2ccc(cc2)c3nc4ccccc4[nH]3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I12 compound treatment 901920.0 -148000.0 -0.72 1346840.0 231000.0 1.38 1002720.0 -107554.375 -0.616016867677277 0.0213 0.0128 1024512 Maybridge1_001068 COc1cc2CCN=C(C)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I13 compound treatment 1219900.0 170000.0 0.83 1271950.0 156000.0 0.93 1096390.0 -13884.375 -0.0795226525853243 0.9709 0.7768 1715965 Maybridge1_001069 Cc1onc(c1C(=O)NCCS(=O)(=O)c2ccc(C)cc2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I14 compound treatment 878240.0 -172000.0 -0.84 883950.0 -232000.0 -1.38 1154960.0 44685.625 0.255936578523202 -1.1312 -0.693 2070014 Maybridge1_001070 NCC(=O)c1cccc(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I15 compound treatment 724930.0 -325000.0 -1.59 858670.0 -257000.0 -1.53 752560.0 -357714.375 -2.04880637175972 -2.9811 -0.991 1230300 Maybridge1_001071 Nc1c(Cl)cc(cc1Cl)C(=O)Nc2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I16 compound treatment 716280.0 -333000.0 -1.63 796280.0 -319000.0 -1.9 780160.0 -330114.375 -1.89072758093515 -3.1285 -0.9976 2070015 Maybridge1_001072 Clc1ccc(COC(=O)c2cccs2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I17 compound treatment 648320.0 -401000.0 -1.96 687630.0 -428000.0 -2.54 595800.0 -514474.375 -2.94664808370394 -4.3028 -0.987 2070016 Maybridge1_001073 Cc1nn(nc1C(=O)NNC(=S)Nc2ccc(C)c(C)c2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I18 compound treatment 741790.0 -308000.0 -1.5 992810.0 -123000.0 -0.73 783940.0 -326334.375 -1.86907765958309 -2.3693 -0.9447 2070017 Maybridge1_001074 Fc1ccc(NC(=O)CS(=O)(=O)Cc2c(F)cccc2Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I19 compound treatment 887770.0 -162000.0 -0.79 1038420.0 -77100.0 -0.46 1006690.0 -103584.375 -0.593278722765191 -1.0643 -0.9762 2070018 Maybridge1_001075 CSC1=NCCCN1C(=O)c2c(C)onc2c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I20 compound treatment 1054780.0 5030.0 0.02 1047810.0 -67800.0 -0.4 988160.0 -122114.375 -0.699409157329661 -0.6223 -0.7705 1565983 Maybridge1_001076 COc1ccc(c2c(C)nn(C)c2C)c(c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I21 compound treatment 825170.0 -225000.0 -1.1 1038090.0 -77500.0 -0.46 860530.0 -249744.375 -1.43040901504489 -1.7254 -0.9272 1063570 Maybridge1_001077 [O-][N+](=O)c1ccc(Oc2ccc(Cl)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I22 compound treatment 1198750.0 149000.0 0.73 1147360.0 31800.0 0.19 1366170.0 255895.625 1.46564025280068 1.3756 0.8351 2070019 Maybridge1_001078 Nc1ccccc1C(=O)NCCCn2ccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I23 mock treatment 1138790.0 89000.0 0.44 1098400.0 -17200.0 -0.1 1212850.0 102575.625 0.587501114785326 0.5314 0.7199 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 I24 mock treatment 1081510.0 31800.0 0.16 1071760.0 -43800.0 -0.26 1252170.0 141895.625 0.812706116786132 0.4084 0.4708 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J01 compound treatment 1006500.0 -43300.0 -0.21 1048640.0 -66900.0 -0.4 1129810.0 19535.625 0.111890144130519 -0.2872 -0.6185 2070020 Maybridge1_001079 CC1CN(CC(C)O1)C2=NCCN2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J02 compound treatment 1103520.0 53800.0 0.26 1299940.0 184000.0 1.1 1089610.0 -20664.375 -0.118355051200926 0.7163 0.6319 2070021 Maybridge1_001080 Fc1ccc(OC(=O)NC(=O)c2c(Cl)cccc2Cl)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J03 compound treatment 1138190.0 88400.0 0.43 1043160.0 -72400.0 -0.43 1058840.0 -51434.375 -0.294589993000642 -0.1692 -0.2498 2070022 Maybridge1_001081 COc1ccccc1Oc2ccc(cc2NC(=O)NC(=O)c3c(F)cccc3Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J04 compound treatment 1037700.0 -12100.0 -0.06 1086970.0 -28600.0 -0.17 1020030.0 -90244.375 -0.516873973866647 -0.4306 -0.7868 1481239 Maybridge1_001082 COc1ccc(cc1OC)S(=O)(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J05 compound treatment 64320.0 -985000.0 -4.81 71690.0 -1040000.0 -6.21 158580.0 -951694.375 -5.45082232009236 -9.5107 -0.9947 2070023 Maybridge1_001083 Cc1cc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])c3c(Cl)ccc(C)c3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J06 compound treatment 907060.0 -143000.0 -0.7 984820.0 -131000.0 -0.78 952760.0 -157514.375 -0.902162389039441 -1.3723 -0.9944 1920653 Maybridge1_001084 Clc1ccc(/C=C\2/N=C(OC2=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J07 compound treatment 1112010.0 62300.0 0.3 1186720.0 71200.0 0.42 1036580.0 -73694.375 -0.422083974296114 0.1762 0.2628 1043741 Maybridge1_001085 CSc1ccc(Br)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J08 compound treatment 922580.0 -127000.0 -0.62 951140.0 -164000.0 -0.98 1236110.0 125835.625 0.720722588501978 -0.5071 -0.3717 2070024 Maybridge1_001086 CC(=O)c1cc(Cl)cc(Cl)c1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J09 compound treatment 538820.0 -511000.0 -2.5 597120.0 -518000.0 -3.08 520800.0 -589474.375 -3.37621001529245 -5.1705 -0.9926 2070025 Maybridge1_001087 Clc1c(sc2ccccc12)C(=O)N/N=C/c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J10 compound treatment 779200.0 -271000.0 -1.32 708610.0 -407000.0 -2.42 791150.0 -319124.375 -1.82778243922638 -3.2156 -0.972 1296994 Maybridge1_001088 Cc1cc(Oc2ccnc3cc(Cl)ccc23)cc(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J11 compound treatment 876000.0 -174000.0 -0.85 888890.0 -227000.0 -1.35 982940.0 -127334.375 -0.729306667768222 -1.6894 -0.9643 2070026 Maybridge1_001089 Cc1cc(ccc1Cl)C(=O)CC(Sc2ccccc2N)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J12 compound treatment 490720.0 -559000.0 -2.73 691610.0 -424000.0 -2.52 499540.0 -610734.375 -3.49797650416675 -5.052 -0.9898 1724700 Maybridge1_001090 Cc1cc(Oc2ccc(Cl)c(C)c2)c3ccccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J13 compound treatment 805210.0 -245000.0 -1.19 1056700.0 -58900.0 -0.35 905010.0 -205264.375 -1.1756501521508 -1.5707 -0.9173 2070027 Maybridge1_001091 Cc1ccc(SCC(=O)Nc2ccc(Br)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J14 compound treatment 838460.0 -211000.0 -1.03 747490.0 -368000.0 -2.19 821690.0 -288584.375 -1.65286482068353 -2.814 -0.9602 2070028 Maybridge1_001092 COC(=O)c1sc2cc(Cl)ccc2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J15 compound treatment 781280.0 -268000.0 -1.31 821800.0 -294000.0 -1.75 808570.0 -301704.375 -1.72800952124942 -2.7636 -0.9922 2070029 Maybridge1_001093 CC(=N)NS(=O)(=O)c1cc(Cl)c(Oc2ccc(cc2)[N+](=O)[O-])c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J16 compound treatment 1060040.0 10300.0 0.05 1060320.0 -55200.0 -0.33 1017770.0 -92504.375 -0.529818106738514 -0.4666 -0.746 1006327 Maybridge1_001094 CCOC(=O)c1cc2ccccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J17 compound treatment 1186330.0 137000.0 0.67 1255160.0 140000.0 0.83 1188640.0 78365.625 0.448838523268552 1.1237 0.9722 2070030 Maybridge1_001095 Cc1ccc(SCC(=O)N2CCN(CC2)c3ccc(cc3[N+](=O)[O-])C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J18 compound treatment 739000.0 -311000.0 -1.52 774660.0 -341000.0 -2.03 686950.0 -423324.375 -2.42458714951336 -3.4468 -0.9831 2070031 Maybridge1_001096 CC(=NNC(=S)Nc1ccc(C)cc1C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J19 compound treatment 1132100.0 82300.0 0.4 1122270.0 6700.0 0.04 1284690.0 174415.625 0.998964170322914 0.832 0.7721 2070032 Maybridge1_001097 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/C=N/OCc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J20 compound treatment 886440.0 -163000.0 -0.8 772390.0 -343000.0 -2.04 774590.0 -335684.375 -1.92262971372112 -2.7489 -0.943 2070033 Maybridge1_001098 Cc1cc(C)c(NC(=S)NN=C2CCCCCC2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J21 compound treatment 977180.0 -72600.0 -0.35 950050.0 -166000.0 -0.98 994610.0 -115664.375 -0.662466831213048 -1.1555 -0.9331 1504079 Maybridge1_001099 COc1ccc(cc1OC)S(=O)(=O)Nc2ccc3oc(=O)c(NC(=O)C)cc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J22 compound treatment 918770.0 -131000.0 -0.64 1098370.0 -17200.0 -0.1 967920.0 -142354.375 -0.815333603934349 -0.8993 -0.8634 2070034 Maybridge1_001100 CS/C(=N/N=C/c1c(Cl)cccc1Cl)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J23 mock treatment 1080920.0 31200.0 0.15 1212650.0 97100.0 0.58 1070110.0 -40164.375 -0.230041153413941 0.2884 0.4508 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 J24 mock treatment 1091520.0 41800.0 0.2 1143840.0 28300.0 0.17 1277990.0 167715.625 0.960589971101006 0.7695 0.7723 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K01 compound treatment 93970.0 -956000.0 -4.67 53210.0 -1060000.0 -6.32 67690.0 -1042584.375 -5.97139410625343 -9.791 -0.9922 2070035 Maybridge1_001101 Cc1cc(cc([N+](=O)[O-])c1Sc2ccc(Cl)cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K02 compound treatment 989570.0 -60200.0 -0.29 1057440.0 -58100.0 -0.35 1068030.0 -42244.375 -0.241954337649996 -0.509 -0.9898 2070036 Maybridge1_001102 Fc1cccc2nc(oc(=O)c12)c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K03 compound treatment 1069600.0 19800.0 0.1 1203200.0 87600.0 0.52 1167610.0 57335.625 0.328389357651132 0.5464 0.8764 2070037 Maybridge1_001103 CC(=O)c1cc2cc(ccc2o1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K04 compound treatment 830400.0 -219000.0 -1.07 907910.0 -208000.0 -1.23 849720.0 -260554.375 -1.49232320811785 -2.1933 -0.9908 1359192 Maybridge1_001104 Cc1cc(Oc2ccc(N)cn2)cc(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K05 compound treatment 1216180.0 166000.0 0.81 1413950.0 298000.0 1.77 1340770.0 230495.625 1.3201619453027 2.2561 0.9575 1364082 Maybridge1_001105 COc1cc(cc(OC)c1OC)C(C#N)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K06 compound treatment 1143520.0 93800.0 0.46 1417350.0 302000.0 1.79 1102650.0 -7624.375 -0.043668550028736 1.2754 0.6884 2070038 Maybridge1_001106 CC(C)(C)SC(=S)SCC(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K07 compound treatment 993870.0 -55900.0 -0.27 1280030.0 164000.0 0.98 1013560.0 -96714.375 -0.553930849831683 0.0872 0.0754 1127157 Maybridge1_001107 Nc1ccc(Cl)cc1C(=O)NCc2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K08 compound treatment 964050.0 -85700.0 -0.42 1098580.0 -17000.0 -0.1 1100960.0 -9314.375 -0.0533480122205306 -0.3309 -0.7623 2070039 Maybridge1_001108 CN(C)c1cc(N2CCCC2)c(F)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K09 compound treatment 1306920.0 257000.0 1.26 1284100.0 169000.0 1.0 1280320.0 170045.625 0.973935028442356 1.8663 0.9931 1208334 Maybridge1_001109 Clc1ccc(cc1Cl)C(=O)NCCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K10 compound treatment 657800.0 -392000.0 -1.92 528890.0 -587000.0 -3.49 741920.0 -368354.375 -2.10974689112108 -4.3379 -0.963 1428930 Maybridge1_001110 CC1CC(C)CN(Cc2cc(C)c(O)c(C)c2)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K11 compound treatment 1146980.0 97200.0 0.48 1413120.0 298000.0 1.77 1226880.0 116605.625 0.667857833454484 1.6814 0.8623 2070040 Maybridge1_001111 COc1ccc(C(C(=O)C)C(=O)C)c(c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K12 compound treatment 1240060.0 190000.0 0.93 1053730.0 -61800.0 -0.37 996570.0 -113704.375 -0.651240946067535 -0.0515 -0.0431 2070041 Maybridge1_001112 Nc1cccc(NC=C(C#N)C#N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K13 compound treatment 1158980.0 109000.0 0.53 1066560.0 -49000.0 -0.29 1252530.0 142255.625 0.814768014057757 0.6103 0.6003 1667067 Maybridge1_001113 Cc1onc(c1C(=O)NCC(=O)NN)c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K14 compound treatment 1037410.0 -12300.0 -0.06 1126480.0 10900.0 0.06 1119880.0 9605.625 0.0550161443881994 0.0344 0.33 1019894 Maybridge1_001114 NCC(=O)c1ccc(Br)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K15 compound treatment 816540.0 -233000.0 -1.14 838500.0 -277000.0 -1.65 869660.0 -240614.375 -1.37811700923952 -2.4048 -0.989 2070042 Maybridge1_001115 Cc1nn(nc1C(=O)Nc2nnc(s2)C(F)(F)F)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K16 compound treatment 747680.0 -302000.0 -1.48 722240.0 -393000.0 -2.34 728720.0 -381554.375 -2.18534979108066 -3.4642 -0.9828 2070043 Maybridge1_001116 Fc1ccc(NC(=O)CSCc2ccc(Cl)c(Cl)c2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K17 compound treatment 572530.0 -477000.0 -2.33 595520.0 -520000.0 -3.09 593510.0 -516764.375 -2.95976404134844 -4.8404 -0.993 2070044 Maybridge1_001117 Cc1nn(nc1C(=O)NNC(=S)Nc2ccc(Cl)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K18 compound treatment 836820.0 -213000.0 -1.04 1070150.0 -45400.0 -0.27 1045860.0 -64414.375 -0.368932844627561 -0.9696 -0.8532 2070045 Maybridge1_001118 N/C(=N\OC(=O)c1cccs1)/c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K19 compound treatment 973760.0 -76000.0 -0.37 1034110.0 -81500.0 -0.48 1101820.0 -8454.375 -0.0484223687383156 -0.522 -0.8526 1104645 Maybridge1_001119 Nc1ccccc1C(=O)NCCc2c[nH]c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K20 compound treatment 1034370.0 -15400.0 -0.08 1172160.0 56600.0 0.34 1102940.0 -7334.375 -0.0420075772265938 0.1266 0.3646 1573183 Maybridge1_001120 Cc1onc(c1C(=O)Oc2ccc(F)cc2Cl)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K21 compound treatment 773720.0 -276000.0 -1.35 815280.0 -300000.0 -1.79 884820.0 -225454.375 -1.29128822413443 -2.5551 -0.989 2070046 Maybridge1_001121 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K22 compound treatment 1075240.0 25500.0 0.12 1257120.0 142000.0 0.84 1203840.0 93565.625 0.535896408070492 0.8673 0.8625 1010836 Maybridge1_001122 CCOC(=O)c1cnc(S)nc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K23 mock treatment 1048900.0 -852.0 0.0 1087520.0 -28000.0 -0.17 1047680.0 -62594.375 -0.358508808421013 -0.3057 -0.773 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 K24 mock treatment 1215900.0 166000.0 0.81 1326480.0 211000.0 1.25 1246400.0 136125.625 0.779658485515922 1.6429 0.9749 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L01 compound treatment 1078720.0 29000.0 0.14 1053370.0 -62200.0 -0.37 1264120.0 153845.625 0.881149651219236 0.3769 0.3901 1703714 Maybridge1_001123 Cc1cccc(c1)c2nc3cccc(F)c3c(=O)o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L02 compound treatment 1044640.0 -5110.0 -0.02 1228050.0 112000.0 0.67 1216880.0 106605.625 0.610582909242682 0.7243 0.7994 2070047 Maybridge1_001124 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)Nc2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L03 compound treatment 1025720.0 -24000.0 -0.12 1158570.0 43000.0 0.26 1273120.0 162845.625 0.932697083009858 0.6183 0.6347 2070048 Maybridge1_001125 [O-][N+](=O)c1cccnc1Sc2ncc3ccccn23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L04 compound treatment 1146810.0 97100.0 0.47 1179010.0 63400.0 0.38 1102740.0 -7534.375 -0.0431530757108298 0.4667 0.7682 1355972 Maybridge1_001126 Clc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L05 compound treatment 912000.0 -138000.0 -0.67 1015000.0 -101000.0 -0.6 1014190.0 -96084.375 -0.550322529606339 -1.0516 -0.9966 2070049 Maybridge1_001127 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3cc(F)ccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L06 compound treatment 1043120.0 -6630.0 -0.03 1186620.0 71100.0 0.42 1165670.0 55395.625 0.317278022354042 0.4084 0.7715 1558904 Maybridge1_001128 Nc1ccccc1C(=O)NCCc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L07 compound treatment 1102460.0 52700.0 0.26 1362250.0 247000.0 1.47 1019780.0 -90494.375 -0.518305846971942 0.6964 0.4416 1540934 Maybridge1_001129 COc1ccc2N(CCCc2c1)C(=O)NC(=O)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L08 compound treatment 1041040.0 -8710.0 -0.04 1148060.0 32500.0 0.19 1049970.0 -60304.375 -0.345392850776511 -0.1124 -0.2825 2070050 Maybridge1_001130 CC(=O)c1cc(F)ccc1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L09 compound treatment 1195270.0 146000.0 0.71 1391970.0 276000.0 1.64 1116390.0 6115.625 0.0350271958382804 1.3797 0.7703 2070051 Maybridge1_001131 CCOC(=O)CNC(=O)c1c(F)cccc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L10 compound treatment 1044680.0 -5070.0 -0.02 1136850.0 21300.0 0.13 987650.0 -122624.375 -0.702330178464463 -0.3467 -0.4856 2070052 Maybridge1_001132 COc1ccc(cc1CSc2nc3cc(ccc3[nH]2)C(F)(F)F)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L11 compound treatment 1235460.0 186000.0 0.91 1365880.0 250000.0 1.49 1263040.0 152765.625 0.874963959404361 1.8884 0.9682 2070053 Maybridge1_001133 Cc1cc(ccc1Cl)C2=Nc3ccccc3SC(C2)c4c(F)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L12 compound treatment 559590.0 -490000.0 -2.39 592360.0 -523000.0 -3.11 630510.0 -479764.375 -2.74784682176477 -4.7654 -0.9944 1583726 Maybridge1_001134 Cc1cc(Oc2ccc(Cl)cc2)c3ccccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L13 compound treatment 1087650.0 37900.0 0.19 1127170.0 11600.0 0.07 1144190.0 33915.625 0.194251485147091 0.2589 0.9343 2070054 Maybridge1_001135 Brc1ccc(NC(=O)CSc2ncccn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L14 compound treatment 594660.0 -455000.0 -2.22 514520.0 -601000.0 -3.57 760200.0 -350074.375 -2.00504832966191 -4.5049 -0.9662 2070055 Maybridge1_001136 COc1ccc(Cc2nc(cs2)C(C)(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L15 compound treatment 1023420.0 -26300.0 -0.13 1039270.0 -76300.0 -0.45 1044880.0 -65394.375 -0.374545787200318 -0.5525 -0.9174 2070056 Maybridge1_001137 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L16 compound treatment 1151250.0 101000.0 0.5 1287590.0 172000.0 1.02 1318930.0 208655.625 1.19507351082412 1.5669 0.95 2070057 Maybridge1_001138 Clc1cc(COc2ccc(cc2)S(=O)(=O)c3ccc(OCc4cc(Cl)cc5COCOc45)cc3)c6OCOCc6c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L17 compound treatment 1182670.0 133000.0 0.65 1213360.0 97800.0 0.58 1235380.0 125105.625 0.716541519034516 1.1244 0.9964 2070058 Maybridge1_001139 CC(=O)N1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L18 compound treatment 1074040.0 24300.0 0.12 1196650.0 81100.0 0.48 1022190.0 -88084.375 -0.504502590236898 0.0556 0.0786 2070059 Maybridge1_001140 Fc1ccc(NC(=O)CC#N)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L19 compound treatment 1043320.0 -6430.0 -0.03 1075230.0 -40300.0 -0.24 1182080.0 71805.625 0.41126617298561 0.0808 0.1694 2070060 Maybridge1_001141 Nc1nc2c(F)cc(F)cc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L20 compound treatment 754310.0 -295000.0 -1.44 621880.0 -494000.0 -2.94 797060.0 -313214.375 -1.7939329590172 -3.5641 -0.9553 2070061 Maybridge1_001142 C/C(=N\NC(=S)N)/c1ccc(Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L21 compound treatment 910950.0 -139000.0 -0.68 1062510.0 -53100.0 -0.32 983360.0 -126914.375 -0.726901120951326 -0.9934 -0.9524 2070062 Maybridge1_001143 Cc1ccc2nc(N)sc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L22 compound treatment 774720.0 -275000.0 -1.34 822930.0 -293000.0 -1.74 886680.0 -223594.375 -1.28063508823103 -2.5199 -0.9904 1919994 Maybridge1_001144 CN(C)c1ccc(/C=N/NC(=S)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L23 mock treatment 1105080.0 55300.0 0.27 1062000.0 -53600.0 -0.32 1074790.0 -35484.375 -0.203236488882817 -0.1452 -0.3125 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 L24 mock treatment 983730.0 -66000.0 -0.32 1320810.0 205000.0 1.22 1041920.0 -68354.375 -0.391499164767012 0.2924 0.2212 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M01 compound treatment 1150770.0 101000.0 0.49 1107630.0 -7940.0 -0.05 1221650.0 111375.625 0.637903048091712 0.626 0.7748 1469999 Maybridge1_001145 NC(=O)c1cccnc1Oc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M02 compound treatment 1068640.0 18900.0 0.09 1187700.0 72100.0 0.43 1168350.0 58075.625 0.332627702042805 0.493 0.8954 1365534 Maybridge1_001146 CC(C)(C)C(=O)Nc1cccc(F)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M03 compound treatment 1094500.0 44700.0 0.22 1176270.0 60700.0 0.36 1196320.0 86045.625 0.492825665063216 0.6192 0.9543 1075845 Maybridge1_001147 OC(=O)c1ccccc1C(=O)Nc2cc(ccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M04 compound treatment 560920.0 -489000.0 -2.39 584430.0 -531000.0 -3.16 546690.0 -563584.375 -3.2279252365081 -5.0661 -0.9916 1223037 Maybridge1_001148 CC(C)(C)c1ccc(Oc2ccc(N)cn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M05 compound treatment 1261760.0 212000.0 1.04 1309660.0 194000.0 1.15 1320200.0 209925.625 1.20234742619902 1.9586 0.9981 1020373 Maybridge1_001149 Nc1ccc(Br)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M06 compound treatment 961360.0 -88400.0 -0.43 1086080.0 -29500.0 -0.18 1163360.0 53085.625 0.304047514861116 -0.175 -0.3145 2070063 Maybridge1_001150 CC(C)(C)SC(=S)SCC(=O)c1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M07 compound treatment 1068650.0 18900.0 0.09 1379550.0 264000.0 1.57 1245020.0 134745.625 0.771754545974694 1.4052 0.8022 1571162 Maybridge1_001151 CNc1ccccc1C(=O)NCc2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M08 compound treatment 860170.0 -190000.0 -0.93 931880.0 -184000.0 -1.09 866400.0 -243874.375 -1.39678863453257 -1.9719 -0.9857 2070064 Maybridge1_001152 CC1CCCN(C1)c2cc(N(C)C)c(cc2F)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M09 compound treatment 1391060.0 341000.0 1.67 1359940.0 244000.0 1.45 1287250.0 176975.625 1.01362655092113 2.387 0.981 1632631 Maybridge1_001153 O=C(NCCc1ccncc1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M10 compound treatment 1001070.0 -48700.0 -0.24 1094840.0 -20700.0 -0.12 1292220.0 181945.625 1.0420921882544 0.3932 0.3654 1432647 Maybridge1_001154 COc1cc2CCN(Cc3cc(C)c(O)c(C)c3)C(C)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M11 compound treatment 1069600.0 19800.0 0.1 1251840.0 136000.0 0.81 1244920.0 134645.625 0.771181796732576 0.9691 0.8631 2070065 Maybridge1_001155 Clc1ccc(SCC(=O)NCc2cccs2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M12 compound treatment 1136260.0 86500.0 0.42 1173870.0 58300.0 0.35 1203770.0 93495.625 0.535495483601009 0.7534 0.9845 2070066 Maybridge1_001156 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)N3CCCCC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M13 compound treatment 1235550.0 186000.0 0.91 1156200.0 40600.0 0.24 1251250.0 140975.625 0.807436823758646 1.1298 0.9121 2070067 Maybridge1_001157 COc1cc(cc(OC)c1OC)C2=NNC(=O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M14 compound treatment 799080.0 -251000.0 -1.22 894930.0 -221000.0 -1.31 972980.0 -137294.375 -0.786352492283177 -1.9186 -0.9791 2070068 Maybridge1_001158 Fc1ccc(OC(=O)c2cccs2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M15 compound treatment 822260.0 -227000.0 -1.11 826480.0 -289000.0 -1.72 821850.0 -288424.375 -1.65194842189615 -2.588 -0.9838 1504770 Maybridge1_001159 Cc1nn(nc1C(=O)Nc2ccc3[nH]ncc3c2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M16 compound treatment 1043050.0 -6700.0 -0.03 1126670.0 11100.0 0.07 1152720.0 42445.625 0.243106995499758 0.1596 0.6281 2070069 Maybridge1_001160 Fc1ccc(NC(=O)CSCc2c(Cl)cccc2Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M17 compound treatment 1252230.0 202000.0 0.99 1171520.0 56000.0 0.33 1312520.0 202245.625 1.15836028440436 1.432 0.9184 1236643 Maybridge1_001161 Fc1cccc(F)c1C(=O)NC(=O)N2CCSC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M18 compound treatment 1009030.0 -40700.0 -0.2 1056990.0 -58600.0 -0.35 1050170.0 -60104.375 -0.344247352292275 -0.5147 -0.9737 1108196 Maybridge1_001162 [O-][N+](=O)c1ccc(cc1)c2noc(n2)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M19 compound treatment 1059470.0 9720.0 0.05 1254970.0 139000.0 0.83 1180970.0 70695.625 0.4049086563981 0.7398 0.8008 1093772 Maybridge1_001163 O=C(Nc1nncs1)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M20 compound treatment 1149530.0 99800.0 0.49 1357990.0 242000.0 1.44 1267650.0 157375.625 0.901367699466002 1.6342 0.9239 1737692 Maybridge1_001164 CC(=O)Nc1cccc(F)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M21 compound treatment 896610.0 -153000.0 -0.75 991540.0 -124000.0 -0.74 1030240.0 -80034.375 -0.458396276246397 -1.1225 -0.9792 2070070 Maybridge1_001165 Cc1cc(Oc2ccc(cn2)[N+](=O)[O-])cc(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M22 compound treatment 1145920.0 96200.0 0.47 1138320.0 22800.0 0.14 1248650.0 138375.625 0.792545343463578 0.807 0.8665 2070071 Maybridge1_001166 CC(C)(C)c1cc([N+](=O)[O-])c(OC(=O)c2ccc(Cl)cc2Cl)c(c1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M23 mock treatment 1027940.0 -21800.0 -0.11 1086180.0 -29400.0 -0.17 1085180.0 -25094.375 -0.143727842626755 -0.2454 -0.9812 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 M24 mock treatment 1037380.0 -12400.0 -0.06 1214880.0 99300.0 0.59 976290.0 -133984.375 -0.76739449236907 -0.137 -0.1412 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N01 compound treatment 1038130.0 -11600.0 -0.06 968000.0 -148000.0 -0.88 1146400.0 36125.625 0.206909243397899 -0.42 -0.4649 1602236 Maybridge1_001167 S=C(NCc1ccccn1)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N02 compound treatment 1159920.0 110000.0 0.54 1308810.0 193000.0 1.15 1213080.0 102805.625 0.588818438042197 1.3142 0.9394 1628081 Maybridge1_001168 Cc1onc(c1C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N03 compound treatment 971970.0 -77800.0 -0.38 1100230.0 -15300.0 -0.09 1033210.0 -77064.375 -0.441385623755491 -0.5269 -0.8937 2070072 Maybridge1_001169 [O-][N+](=O)c1ccc(Sc2ncc3ccccn23)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N04 compound treatment 1240510.0 191000.0 0.93 1352210.0 237000.0 1.41 1276680.0 166405.625 0.95308695602926 1.9008 0.9806 1468368 Maybridge1_001170 Clc1ccc(Oc2ccccc2NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N05 compound treatment 1116380.0 66600.0 0.33 1247360.0 132000.0 0.78 1184980.0 74705.625 0.427875901007032 0.8875 0.9338 2070073 Maybridge1_001171 Cc1cc(Oc2ncccc2[N+](=O)[O-])c3cc(Cl)ccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N06 compound treatment 218970.0 -831000.0 -4.06 192920.0 -923000.0 -5.49 228050.0 -882224.375 -5.05293342159297 -8.4285 -0.9925 1602444 Maybridge1_001172 Cc1c(Cl)cccc1Nc2nc(cs2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N07 compound treatment 1153280.0 104000.0 0.51 1220330.0 105000.0 0.62 1241150.0 130875.625 0.749589150304726 1.0845 0.9876 2070074 Maybridge1_001173 Clc1ccc(cc1)C2=NNC(=O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N08 compound treatment 1154040.0 104000.0 0.51 1211070.0 95500.0 0.57 1181660.0 71385.625 0.408860626168714 0.8581 0.9913 2070075 Maybridge1_001174 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/c2cc(F)ccc2OC(=O)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N09 compound treatment 881660.0 -168000.0 -0.82 945890.0 -170000.0 -1.01 995490.0 -114784.375 -0.65742663788241 -1.4363 -0.9853 2070076 Maybridge1_001175 C/C(=N\Nc1ccccc1)/C=N/O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N10 compound treatment 965080.0 -84700.0 -0.41 999140.0 -116000.0 -0.69 1017410.0 -92864.375 -0.531880004010139 -0.9457 -0.9788 1595657 Maybridge1_001176 Cc1ccc(cc1C)n2c(csc2=Nc3ccccn3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N11 compound treatment 1117640.0 67900.0 0.33 1182180.0 66600.0 0.4 1161140.0 50865.625 0.291332481686096 0.5884 0.992 2070077 Maybridge1_001177 Cc1cc(ccc1Cl)C2=Nc3ccccc3SC(C2)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N12 compound treatment 574450.0 -475000.0 -2.32 589650.0 -526000.0 -3.13 608280.0 -501994.375 -2.87516897828761 -4.8063 -0.9927 1257335 Maybridge1_001178 Fc1ccc(Oc2ccnc3cc(Cl)ccc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N13 compound treatment 896000.0 -154000.0 -0.75 869930.0 -246000.0 -1.46 896670.0 -213604.375 -1.22341743894344 -1.9834 -0.9684 2070078 Maybridge1_001179 Fc1cc(Br)c(c(Br)c1Cl)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N14 compound treatment 610570.0 -439000.0 -2.15 722180.0 -393000.0 -2.34 740120.0 -370154.375 -2.12005637747921 -3.8135 -0.999 2070079 Maybridge1_001180 Cc1ccc(Cc2nc(cs2)C(C)(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N15 compound treatment 1211430.0 162000.0 0.79 1299360.0 184000.0 1.09 1113860.0 3585.625 0.0205366400126944 1.0989 0.8148 2070080 Maybridge1_001181 CS(=O)(=O)NNc1c(Cl)cc(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N16 compound treatment 910800.0 -139000.0 -0.68 1046780.0 -68800.0 -0.41 908320.0 -201954.375 -1.15669215223669 -1.2959 -0.9242 1633692 Maybridge1_001182 Cc1onc(c1C(=O)Nc2nnc(s2)C3CC3)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N17 compound treatment 1225020.0 175000.0 0.86 1251780.0 136000.0 0.81 1254900.0 144625.625 0.828342171095954 1.4403 0.9997 1014750 Maybridge1_001183 COc1ccc(NC(=O)CC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N18 compound treatment 800810.0 -249000.0 -1.22 836690.0 -279000.0 -1.66 955210.0 -155064.375 -0.88813003260755 -2.1724 -0.9698 2070081 Maybridge1_001184 Fc1ccc(OCOc2ccc(F)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N19 compound treatment 1125760.0 76000.0 0.37 1230330.0 115000.0 0.68 1302570.0 192295.625 1.10137173481362 1.2443 0.9232 2070082 Maybridge1_001185 Oc1ccnc(SCc2c(Cl)cccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N20 compound treatment 560530.0 -489000.0 -2.39 575310.0 -540000.0 -3.21 552700.0 -557574.375 -3.1935030070568 -5.0786 -0.9916 2070083 Maybridge1_001186 CS/C(=N/N=C(\C)/c1ccc(Cl)c(Cl)c1)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N21 compound treatment 962170.0 -87600.0 -0.43 1071050.0 -44500.0 -0.26 1056360.0 -53914.375 -0.308794174205169 -0.5782 -0.9793 2070084 Maybridge1_001187 Nc1nc2ccc(Cl)cc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N22 compound treatment 833560.0 -216000.0 -1.06 881780.0 -234000.0 -1.39 897330.0 -212944.375 -1.21963729394546 -2.1167 -0.9938 2070085 Maybridge1_001188 NC(=S)N/N=C/c1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N23 mock treatment 1254880.0 205000.0 1.0 1361030.0 245000.0 1.46 1342480.0 232205.625 1.32995595734292 2.1892 0.9886 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 N24 mock treatment 1088020.0 38300.0 0.19 1123240.0 7670.0 0.05 1088820.0 -21454.375 -0.122879770213659 0.0633 0.2774 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O01 compound treatment 919270.0 -130000.0 -0.64 1136440.0 20900.0 0.12 975360.0 -134914.375 -0.772721060320768 -0.7425 -0.7356 1177922 Maybridge1_001189 O=c1c2ccccc2oc3ncccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O02 compound treatment 1230080.0 180000.0 0.88 1278190.0 163000.0 0.97 1249860.0 139585.625 0.799475609293206 1.5286 0.997 1120165 Maybridge1_001190 Fc1cccc(NC(=O)C(C2CCCC2)c3ccccc3)c1C(=O)NCc4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O03 compound treatment 1194560.0 145000.0 0.71 1313880.0 198000.0 1.18 1250810.0 140535.625 0.804916727093327 1.5541 0.9753 2070086 Maybridge1_001191 COC(=O)c1c(OC)ccc([N+](=O)[O-])c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O04 compound treatment 1030320.0 -19400.0 -0.09 1152050.0 36500.0 0.22 1094160.0 -16114.375 -0.0922949606845562 0.0171 0.0675 2070087 Maybridge1_001192 Cc1cc(Oc2ccc(cn2)[N+](=O)[O-])ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O05 compound treatment 1169620.0 120000.0 0.59 1313800.0 198000.0 1.18 1296580.0 186305.625 1.06706405521075 1.6348 0.9648 1033922 Maybridge1_001193 Nc1ncc(Br)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O06 compound treatment 1001230.0 -48500.0 -0.24 1097380.0 -18200.0 -0.11 1146160.0 35885.625 0.205534645216816 -0.0807 -0.243 1034245 Maybridge1_001194 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O07 compound treatment 888280.0 -161000.0 -0.79 1063790.0 -51800.0 -0.31 982880.0 -127394.375 -0.729650317313493 -1.0545 -0.9433 1249559 Maybridge1_001195 OC(=O)c1ccccc1NCC(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O08 compound treatment 1270130.0 220000.0 1.08 1139290.0 23700.0 0.14 1236800.0 126525.625 0.724674558272592 1.1215 0.859 1221542 Maybridge1_001196 Clc1ccc(NC(=O)NC(=O)c2ccccc2N3CCCCC3)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O09 compound treatment 1287410.0 238000.0 1.16 1397180.0 282000.0 1.67 1378750.0 268475.625 1.53769210745913 2.525 0.9891 1284064 Maybridge1_001197 CC(C)NC(=S)NCCc1ccncc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O10 compound treatment 1213400.0 164000.0 0.8 1219920.0 104000.0 0.62 1253320.0 143045.625 0.81929273307049 1.2929 0.9929 2070088 Maybridge1_001198 [O-][N+](=O)c1cccnc1Sc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O11 compound treatment 1247690.0 198000.0 0.97 1339690.0 224000.0 1.33 1299200.0 188925.625 1.08207008535424 1.9525 0.991 2070089 Maybridge1_001199 SC1=NCN(CCc2ccncc2)CN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O12 compound treatment 1201500.0 152000.0 0.74 1266930.0 151000.0 0.9 1193280.0 83005.625 0.475414088102828 1.2222 0.9705 2070090 Maybridge1_001200 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)N3CCOCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O13 compound treatment 1139840.0 90100.0 0.44 1093070.0 -22500.0 -0.13 1148800.0 38525.625 0.220655225208732 0.3043 0.5964 2070091 Maybridge1_001201 CC(=O)C(=NNc1ccc(F)cc1F)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O14 compound treatment 890040.0 -160000.0 -0.78 879840.0 -236000.0 -1.4 951210.0 -159064.375 -0.91104000229227 -1.7858 -0.9679 2070092 Maybridge1_001202 Fc1ccc(OC(=O)c2ccccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O15 compound treatment 961940.0 -87800.0 -0.43 1043430.0 -72100.0 -0.43 1012270.0 -98004.375 -0.561319315055005 -0.8195 -0.9914 2070093 Maybridge1_001203 Cc1nn(nc1C(=O)NN)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O16 compound treatment 890900.0 -159000.0 -0.78 1087170.0 -28400.0 -0.17 1010140.0 -100134.375 -0.573518873912119 -0.8767 -0.8949 2070094 Maybridge1_001204 Fc1ccc(NC(=O)CSCc2c(F)cccc2Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O17 compound treatment 927750.0 -122000.0 -0.6 935200.0 -180000.0 -1.07 982080.0 -128194.375 -0.734232311250437 -1.3873 -0.9702 1542709 Maybridge1_001205 Cc1ccc(SCc2ccc(cc2)C(=O)Nc3ccc(C)cc3O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O18 compound treatment 1074720.0 25000.0 0.12 1259040.0 143000.0 0.85 1169680.0 59405.625 0.340245266962975 0.7594 0.8196 2070095 Maybridge1_001206 CC1CN(CC(C)O1)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O19 compound treatment 1147770.0 98000.0 0.48 1011140.0 -104000.0 -0.62 1191680.0 81405.625 0.46625010022894 0.1872 0.2051 1582082 Maybridge1_001207 CCc1nnc(NC(=O)c2ccncc2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O20 compound treatment 965200.0 -84600.0 -0.41 1199370.0 83800.0 0.5 1207520.0 97245.625 0.556973580180435 0.3708 0.4342 1207012 Maybridge1_001208 S=C1NCN(CN1)C2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O21 compound treatment 1144160.0 94400.0 0.46 1191840.0 76300.0 0.45 1241540.0 131265.625 0.751822872348986 0.9622 0.9702 2070096 Maybridge1_001209 Fc1cc2nn[nH]c2cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O22 compound treatment 1059080.0 9330.0 0.05 1160880.0 45300.0 0.27 1132740.0 22465.625 0.128671696924577 0.2562 0.8481 2070097 Maybridge1_001210 CCOC(=O)c1cnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)nc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O23 mock treatment 1180320.0 131000.0 0.64 1299110.0 184000.0 1.09 1314010.0 203735.625 1.16689424811192 1.6722 0.9719 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 O24 mock treatment 1003260.0 -46500.0 -0.23 957310.0 -158000.0 -0.94 1112770.0 2495.625 0.0142936732736079 -0.6662 -0.6881 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P01 compound treatment 897090.0 -153000.0 -0.75 1026960.0 -88600.0 -0.53 894150.0 -216124.375 -1.23785071984481 -1.4495 -0.9423 1307492 Maybridge1_001211 Clc1ccc(cc1)S(=O)(=O)NC2CCS(=O)(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P02 compound treatment 1032920.0 -16800.0 -0.08 1084190.0 -31400.0 -0.19 1123140.0 12865.625 0.0736877696812469 -0.1127 -0.5196 1494020 Maybridge1_001212 Cc1onc(c1C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P03 compound treatment 1163040.0 113000.0 0.55 1267680.0 152000.0 0.9 1298260.0 187985.625 1.07668624247833 1.4634 0.9684 2070098 Maybridge1_001213 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3c(Cl)ccc(C)c3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P04 compound treatment 987720.0 -62000.0 -0.3 1166620.0 51100.0 0.3 1061820.0 -48454.375 -0.277522065585525 -0.1599 -0.313 2070099 Maybridge1_001214 Clc1ccc(Oc2ccccc2NC(=O)C(Cl)(Cl)Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P05 compound treatment 481800.0 -568000.0 -2.77 608290.0 -507000.0 -3.02 537250.0 -573024.375 -3.28199276496404 -5.2386 -0.9977 2070100 Maybridge1_001215 Cc1cc(Oc2ncccc2[N+](=O)[O-])c3ccccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P06 compound treatment 344020.0 -706000.0 -3.45 306030.0 -810000.0 -4.81 403380.0 -706894.375 -4.04873217538744 -7.1076 -0.9908 1419346 Maybridge1_001216 Cc1ccc(Nc2nc(cs2)C(C)(C)C)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P07 compound treatment 847680.0 -202000.0 -0.99 885440.0 -230000.0 -1.37 908320.0 -201954.375 -1.15669215223669 -2.0279 -0.9912 1133002 Maybridge1_001217 COc1cc(cc(OC)c1OC)C(=O)c2ccccc2C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P08 compound treatment 1181600.0 132000.0 0.64 1285050.0 169000.0 1.01 1143010.0 32735.625 0.187493044090098 1.062 0.8772 2070101 Maybridge1_001218 CCOc1c(Br)cc(Br)cc1/C=C\2/SC(=S)NC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P09 compound treatment 1170360.0 121000.0 0.59 1178520.0 63000.0 0.37 1145790.0 35515.625 0.203415473020979 0.6738 0.9266 1920882 Maybridge1_001219 Clc1cccc(Cl)c1/C=N/NC(=O)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P10 compound treatment 711950.0 -338000.0 -1.65 718400.0 -397000.0 -2.36 666600.0 -443674.375 -2.54114162028438 -3.7836 -0.9848 2070102 Maybridge1_001220 OC1(CSc2nc3cc(ccc3n21)C(F)(F)F)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P11 compound treatment 838300.0 -211000.0 -1.03 889730.0 -226000.0 -1.34 926310.0 -183964.375 -1.05365456357966 -1.9802 -0.9924 2070103 Maybridge1_001221 CCCc1cc(Br)c(c(Br)c1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P12 compound treatment 662830.0 -387000.0 -1.89 760420.0 -355000.0 -2.11 714190.0 -396084.375 -2.26857025596041 -3.6205 -0.9973 1410530 Maybridge1_001222 Clc1ccc(Oc2ccnc3cc(Cl)ccc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P13 compound treatment 866890.0 -183000.0 -0.89 881440.0 -234000.0 -1.39 884730.0 -225544.375 -1.29180369845233 -2.0655 -0.9841 2070104 Maybridge1_001223 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccc(Cl)cc3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P14 compound treatment 751160.0 -299000.0 -1.46 815300.0 -300000.0 -1.79 776230.0 -334044.375 -1.91323662615039 -2.9778 -0.9939 2070105 Maybridge1_001224 CC(C)(C)c1csc(Cc2ccc(cc2)[N+](=O)[O-])n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P15 compound treatment 477250.0 -573000.0 -2.8 612920.0 -503000.0 -2.99 732000.0 -378274.375 -2.16656361593919 -4.5915 -0.9913 2070106 Maybridge1_001225 Clc1cc(Cl)c(NNS(=O)(=O)c2ccc(Cl)c(Cl)c2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P16 compound treatment 999920.0 -49800.0 -0.24 1163470.0 47900.0 0.28 885920.0 -224354.375 -1.28498798247113 -0.718 -0.5364 2070107 Maybridge1_001226 COC(=O)/C=C/1\SC(=NC1=O)Cc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P17 compound treatment 373470.0 -676000.0 -3.3 372740.0 -743000.0 -4.42 355320.0 -754954.375 -4.32399546114936 -6.9545 -0.9922 1036063 Maybridge1_001227 Clc1ccc(NC(=S)Nc2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P18 compound treatment 731840.0 -318000.0 -1.55 850130.0 -265000.0 -1.58 745380.0 -364894.375 -2.0899297673438 -3.0147 -0.9901 2070108 Maybridge1_001228 Fc1cccc(NC(=S)NN=C2CCCCCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P19 compound treatment 1106560.0 56800.0 0.28 1113970.0 -1600.0 -0.01 1158100.0 47825.625 0.273920904725708 0.3129 0.8022 2070109 Maybridge1_001229 CC(=O)Nc1cc2cc(NC(=O)c3ccc(cc3)[N+](=O)[O-])ccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P20 compound treatment 512100.0 -538000.0 -2.63 596670.0 -519000.0 -3.09 535330.0 -574944.375 -3.29298955041271 -5.1993 -0.9957 2070110 Maybridge1_001230 C/C(=N\Nc1nc(cs1)C(C)(C)C)/c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P21 compound treatment 769280.0 -280000.0 -1.37 820570.0 -295000.0 -1.75 821450.0 -288824.375 -1.65423941886462 -2.759 -0.9948 1723356 Maybridge1_001231 Clc1ccc2sc(NC(=O)NC(=O)c3c(Cl)cccc3Cl)nc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P22 compound treatment 176770.0 -873000.0 -4.27 129310.0 -986000.0 -5.86 146840.0 -963434.375 -5.51806308111701 -9.0345 -0.9914 2070111 Maybridge1_001232 CC(C)(C)c1csc(N/N=C/c2ccc(Cl)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P23 mock treatment 1084740.0 35000.0 0.17 1125600.0 10000.0 0.06 1181520.0 71245.625 0.408058777229749 0.3687 0.826 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.544 P24 mock treatment 934100.0 -116000.0 -0.57 1034560.0 -81000.0 -0.48 1115420.0 5145.625 0.0294715281897355 -0.5873 -0.7904 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A01 compound treatment 812480.0 -284000.0 -1.39 813920.0 -320000.0 -1.91 768750.0 -220076.5625 -1.26048684379815 -2.6296 -0.9836 2070112 Maybridge1_001233 CS/C(=N\N=C(/C)\c1ccc(Br)cc1)/N=C/N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A02 compound treatment 959690.0 -137000.0 -0.67 947740.0 -187000.0 -1.11 850640.0 -138186.5625 -0.791462489427698 -1.4841 -0.9774 2070113 Maybridge1_001234 CC(C)c1ccc(cc1)S(=O)(=O)NC(=N)CSc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A03 compound treatment 953050.0 -144000.0 -0.7 1003400.0 -131000.0 -0.78 864450.0 -124376.5625 -0.712365819091199 -1.266 -0.9989 2070114 Maybridge1_001235 Cc1onc(c1C(=O)Oc2ccc(cc2)c3ccc(OC(=O)c4c(C)onc4c5c(Cl)cccc5Cl)cc3)c6c(Cl)cccc6Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A04 compound treatment 947310.0 -149000.0 -0.73 900970.0 -233000.0 -1.39 828490.0 -160336.5625 -0.918326446556841 -1.7528 -0.9646 2070115 Maybridge1_001236 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1OC(=O)c2c(F)cccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A05 compound treatment 986770.0 -110000.0 -0.54 1001200.0 -133000.0 -0.79 858460.0 -130366.5625 -0.746673498694069 -1.1983 -0.9874 2070116 Maybridge1_001237 Fc1ccc(NC(=O)CC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A06 compound treatment 1046280.0 -50500.0 -0.25 1058170.0 -76100.0 -0.45 895630.0 -93196.5625 -0.5337826053988 -0.7119 -0.9593 2070117 Maybridge1_001238 OCCCc1nc2cc(ccc2[nH]1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A07 compound treatment 1049530.0 -47200.0 -0.23 1054090.0 -80200.0 -0.48 857680.0 -131146.5625 -0.75114094278259 -0.8422 -0.9163 1705513 Maybridge1_001239 COC(=O)c1sc2ccccc2c1OC(=O)c3cccnc3Oc4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A08 compound treatment 852370.0 -244000.0 -1.19 891400.0 -243000.0 -1.44 686440.0 -302386.5625 -1.73191674498549 -2.5232 -0.9888 2070118 Maybridge1_001240 CCOC(=O)c1cc(CC)sc1NC(=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A09 compound treatment 788690.0 -308000.0 -1.51 818610.0 -316000.0 -1.88 641160.0 -347666.5625 -1.99125760181653 -3.1025 -0.9933 2070119 Maybridge1_001241 CSC1=NC=C(C#N)C2=NC(NN21)c3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A10 compound treatment 1032700.0 -64000.0 -0.31 1124450.0 -9860.0 -0.06 887200.0 -101626.5625 -0.582065366509349 -0.5505 -0.8298 1020861 Maybridge1_001242 [O-][N+](=O)c1ccc(cc1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A11 compound treatment 1160000.0 63300.0 0.31 1149620.0 15300.0 0.09 886340.0 -102486.5625 -0.586991009991564 -0.1079 -0.1611 1214080 Maybridge1_001243 Clc1ccc(cc1Cl)S(=O)(=O)Nc2ccc3oc4ncccc4c(=O)c3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A12 compound treatment 1025540.0 -71200.0 -0.35 1023610.0 -111000.0 -0.66 846400.0 -142426.5625 -0.815747057293503 -1.0519 -0.9524 2070120 Maybridge1_001244 Cc1cc(OC(=O)c2c(C)onc2c3ccccc3)n(n1)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A13 compound treatment 1037940.0 -58800.0 -0.29 968550.0 -166000.0 -0.99 725190.0 -263636.5625 -1.50997641366476 -1.6067 -0.8799 2070121 Maybridge1_001245 [O-][N+](=O)c1cc(ccc1OC(=O)c2c(F)cccc2F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A14 compound treatment 982990.0 -114000.0 -0.56 962180.0 -172000.0 -1.02 806970.0 -181856.5625 -1.04158208346064 -1.5132 -0.9684 2070122 Maybridge1_001246 Nc1cc(ccc1N2CCCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A15 compound treatment 285410.0 -811000.0 -3.96 311680.0 -823000.0 -4.89 184570.0 -804256.5625 -4.60637336640322 -7.7724 -0.9963 2070123 Maybridge1_001247 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(Cl)c(Cl)c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A16 compound treatment 923710.0 -173000.0 -0.85 873350.0 -261000.0 -1.55 681600.0 -307226.5625 -1.75963780830401 -2.3999 -0.9624 2070124 Maybridge1_001248 Cc1cc(OC(=O)c2cccc(F)c2)n(n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A17 compound treatment 1132860.0 36100.0 0.18 1164890.0 30600.0 0.18 944120.0 -44706.5625 -0.25605649789577 0.0591 0.1639 2070125 Maybridge1_001249 Fc1ccc(cc1)c2cnc3c(Cl)cc(cc3n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A18 compound treatment 1149800.0 53100.0 0.26 1212000.0 77700.0 0.46 949760.0 -39066.5625 -0.223753440640314 0.2872 0.4995 2070126 Maybridge1_001250 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)NCC2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A19 compound treatment 1189600.0 92900.0 0.45 1065560.0 -68700.0 -0.41 856690.0 -132136.5625 -0.756811160279558 -0.411 -0.4226 2070127 Maybridge1_001251 CC(C)(COC(=O)c1ccc(o1)[N+](=O)[O-])Nc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A20 compound treatment 1082600.0 -14100.0 -0.07 1137920.0 3610.0 0.02 925120.0 -63706.5625 -0.364878853898195 -0.2381 -0.6402 2070128 Maybridge1_001252 Oc1cc(ccc1[N+](=O)[O-])N2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A21 compound treatment 1025920.0 -70800.0 -0.35 1083880.0 -50400.0 -0.3 879800.0 -109026.5625 -0.624448810426083 -0.7334 -0.9472 2070129 Maybridge1_001253 O=C/1NC(=S)S\C1=C/c2ccc(C#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A22 compound treatment 1108220.0 11500.0 0.06 1061470.0 -72800.0 -0.43 1035700.0 46873.4375 0.268467258035915 -0.0627 -0.1223 2070130 Maybridge1_001254 CCC(CC)(NC(=O)NC(=O)c1ccc(F)c(Cl)c1)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A23 mock treatment 1118080.0 21300.0 0.1 1186400.0 52100.0 0.31 963880.0 -24946.5625 -0.142881247653249 0.1566 0.4389 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 A24 mock treatment 1015520.0 -81200.0 -0.4 917600.0 -217000.0 -1.29 958720.0 -30106.5625 -0.172435108546539 -1.0727 -0.7891 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B01 compound treatment 1037560.0 -59200.0 -0.29 1024350.0 -110000.0 -0.65 856200.0 -132626.5625 -0.759617631565936 -0.983 -0.9423 1223843 Maybridge1_001255 COC(=O)c1sccc1OC(=O)c2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B02 compound treatment 992020.0 -105000.0 -0.51 998110.0 -136000.0 -0.81 879280.0 -109546.5625 -0.627427106485097 -1.1252 -0.9826 1150918 Maybridge1_001256 CCCc1cc(=O)oc2n(nc(C)c12)c3cccc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B03 compound treatment 805990.0 -291000.0 -1.42 875740.0 -259000.0 -1.54 719120.0 -269706.5625 -1.54474229266132 -2.5997 -0.9993 2070131 Maybridge1_001257 [O-][N+](=O)c1cc(ccc1NCCCn2ccnc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B04 compound treatment 996160.0 -101000.0 -0.49 968800.0 -166000.0 -0.98 789200.0 -199626.5625 -1.14335962378501 -1.5121 -0.953 2070132 Maybridge1_001258 Oc1cc(ccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B05 compound treatment 1064280.0 -32500.0 -0.16 1064040.0 -70300.0 -0.42 829160.0 -159666.5625 -0.91448902663465 -0.8608 -0.8457 2070133 Maybridge1_001259 CN(C)/C=N/c1nnc(Sc2nc3cc(Cl)ccc3s2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B06 compound treatment 1051940.0 -44800.0 -0.22 1031120.0 -103000.0 -0.61 850720.0 -138106.5625 -0.791004290034004 -0.9373 -0.9147 2070134 Maybridge1_001260 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(OCc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B07 compound treatment 970760.0 -126000.0 -0.62 920380.0 -214000.0 -1.27 774110.0 -214716.5625 -1.22978748442062 -1.7998 -0.9607 1257406 Maybridge1_001261 Clc1ccc2sc3nc4ccccc4c(=O)n3c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B08 compound treatment 984720.0 -112000.0 -0.55 1046430.0 -87900.0 -0.52 899390.0 -89436.5625 -0.512247233895162 -0.9134 -0.9996 2070135 Maybridge1_001262 O=C1NCCCCC1N2CNC(=S)NC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B09 compound treatment 1121230.0 24500.0 0.12 1136770.0 2460.0 0.01 902250.0 -86576.5625 -0.495866605570587 -0.2087 -0.409 2070136 Maybridge1_001263 CN1N=C(C)/C(=C\c2c(C)nn(C)c2O)/C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B10 compound treatment 1181770.0 85000.0 0.42 1018570.0 -116000.0 -0.69 838640.0 -150186.5625 -0.860192398481861 -0.6541 -0.5556 2070137 Maybridge1_001264 Clc1ccc(cc1Cl)C(=O)NNC(=O)c2cnn(n2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B11 compound treatment 1097610.0 874.0 0.0 1061450.0 -72900.0 -0.43 891680.0 -97146.5625 -0.556406200462462 -0.5689 -0.8067 2070138 Maybridge1_001265 Cc1nn(C)c2oc(=O)c(Cl)c(C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B12 compound treatment 1188640.0 91900.0 0.45 1016880.0 -117000.0 -0.7 823710.0 -165116.5625 -0.945703860330082 -0.6899 -0.5482 2070139 Maybridge1_001266 Cc1ccc(cc1)S(=O)(=O)Oc2cc(ccc2[N+](=O)[O-])S(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B13 compound treatment 1058990.0 -37700.0 -0.18 1063950.0 -70400.0 -0.42 886800.0 -102026.5625 -0.584356363477821 -0.6854 -0.9238 2070140 Maybridge1_001267 Clc1ccc(cc1)c2nnnn2c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B14 compound treatment 1092320.0 -4420.0 -0.02 1214720.0 80400.0 0.48 950430.0 -38396.5625 -0.219916020718123 0.1367 0.2594 1063878 Maybridge1_001268 Cc1ccc(C)c(c1)C(O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B15 compound treatment 778880.0 -318000.0 -1.55 823000.0 -311000.0 -1.85 655200.0 -333626.5625 -1.91084360822316 -3.0686 -0.9961 2070141 Maybridge1_001269 Cc1cc(SCC#N)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B16 compound treatment 1179270.0 82500.0 0.4 1300720.0 166000.0 0.99 1037760.0 48933.4375 0.280265892423547 0.966 0.8744 2070142 Maybridge1_001270 CC(C)(C)c1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)ccc1Oc3ccc(cc3[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B17 compound treatment 1123200.0 26500.0 0.13 1100000.0 -34300.0 -0.2 994470.0 5643.4375 0.0323227455106543 -0.0245 -0.1004 1085663 Maybridge1_001271 Cc1cc(ccc1S(=O)(=O)N)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B18 compound treatment 1267850.0 171000.0 0.84 1313120.0 179000.0 1.06 888030.0 -100796.5625 -0.57731154779977 0.7633 0.519 2070143 Maybridge1_001272 Cc1cc(c(C)cc1Cl)S(=O)(=O)c2ccc(cc2[N+](=O)[O-])C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B19 compound treatment 1352440.0 256000.0 1.25 1184980.0 50700.0 0.3 932390.0 -56436.5625 -0.323239983996215 0.7086 0.5348 2070144 Maybridge1_001273 CCCCCSc1ncccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B20 compound treatment 1113170.0 16400.0 0.08 1216050.0 81700.0 0.49 983920.0 -4906.5625 -0.0281022995327971 0.3108 0.6298 1382605 Maybridge1_001274 COC(=O)c1ccccc1NS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B21 compound treatment 1278500.0 182000.0 0.89 1272760.0 138000.0 0.82 912040.0 -76786.5625 -0.439794454767232 0.7342 0.5698 1166413 Maybridge1_001275 CCCSc1ncccc1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B22 compound treatment 1273350.0 177000.0 0.86 1247680.0 113000.0 0.67 983610.0 -5216.5625 -0.029877822183363 0.8702 0.7944 1543350 Maybridge1_001276 COc1cccc(c1)C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B23 mock treatment 1138730.0 42000.0 0.21 1312350.0 178000.0 1.06 1036270.0 47443.4375 0.271731928715988 0.8866 0.7972 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 B24 mock treatment 1151360.0 54600.0 0.27 1026730.0 -108000.0 -0.64 1015540.0 26713.4375 0.153001010824922 -0.1269 -0.1788 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C01 compound treatment 832260.0 -264000.0 -1.29 871740.0 -263000.0 -1.56 785340.0 -203486.5625 -1.16546774453077 -2.3204 -0.9925 2070145 Maybridge1_001277 CSC1=NC=C(C#N)C2=NC(C)(NN21)c3ccc(Br)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C02 compound treatment 951220.0 -146000.0 -0.71 957460.0 -177000.0 -1.05 819790.0 -169036.5625 -0.968155630621109 -1.5766 -0.9876 2070146 Maybridge1_001278 Brc1csc(/C=C/2\N=C(OC2=O)c3ccccc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C03 compound treatment 714590.0 -382000.0 -1.87 675840.0 -458000.0 -2.73 596320.0 -392506.5625 -2.24807836198226 -3.9499 -0.9883 2070147 Maybridge1_001279 CS/C(=N/N=C/c1ccc2OCOc2c1)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C04 compound treatment 194210.0 -903000.0 -4.41 205690.0 -929000.0 -5.52 174410.0 -814416.5625 -4.66456468940241 -8.4271 -0.9953 2070148 Maybridge1_001280 COC(OC)/C(=N/NC(=S)N)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C05 compound treatment 930330.0 -166000.0 -0.81 887910.0 -246000.0 -1.47 776660.0 -212166.5625 -1.21518237874661 -2.0169 -0.9744 2070149 Maybridge1_001281 CCCc1nc2cc(Cl)c(Cl)cc2nc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C06 compound treatment 1179210.0 82500.0 0.4 1163040.0 28700.0 0.17 866010.0 -122816.5625 -0.703430930914158 -0.0748 -0.0903 2070150 Maybridge1_001282 OCCCc1nc2cc(Cl)ccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C07 compound treatment 876040.0 -221000.0 -1.08 896020.0 -238000.0 -1.42 768420.0 -220406.5625 -1.26237691629714 -2.1695 -0.9939 2070151 Maybridge1_001283 N/C(=N\O)/CC(=O)Nc1cc(Cl)cc(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C08 compound treatment 229810.0 -867000.0 -4.24 246730.0 -888000.0 -5.28 213160.0 -775666.5625 -4.44262435808167 -8.0577 -0.9953 2070152 Maybridge1_001284 CCOC(=O)c1cc(CC)sc1NC(=O)C(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C09 compound treatment 80970.0 -1020000.0 -4.96 220800.0 -914000.0 -5.43 259470.0 -729356.5625 -4.17738418405682 -8.4134 -0.9944 2070153 Maybridge1_001285 Cc1cc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C10 compound treatment 886250.0 -210000.0 -1.03 839800.0 -295000.0 -1.75 613700.0 -375126.5625 -2.14853454370214 -2.8453 -0.9624 2070154 Maybridge1_001286 [O-][N+](=O)c1cnc(s1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C11 compound treatment 992020.0 -105000.0 -0.51 936000.0 -198000.0 -1.18 880440.0 -108386.5625 -0.620783215276528 -1.3346 -0.9349 1249008 Maybridge1_001287 COc1ccc(cc1OC)S(=O)(=O)Nc2ccc3oc4ncccc4c(=O)c3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C12 compound treatment 1203090.0 106000.0 0.52 1112160.0 -22100.0 -0.13 825280.0 -163546.5625 -0.936711697228829 -0.3168 -0.2936 2070155 Maybridge1_001288 CCc1nnc(N/C=N/O)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C13 compound treatment 1011610.0 -85100.0 -0.42 994110.0 -140000.0 -0.83 769860.0 -218966.5625 -1.25412932721064 -1.4455 -0.9252 2070156 Maybridge1_001289 CN(C)/C=N/S(=O)(=O)c1cc(Cl)c(Oc2ccc(cc2)[N+](=O)[O-])c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C14 compound treatment 1106670.0 9930.0 0.05 1089440.0 -44900.0 -0.27 891140.0 -97686.5625 -0.559499046369899 -0.449 -0.7222 2070157 Maybridge1_001290 Cc1cc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C15 compound treatment 1157730.0 61000.0 0.3 996450.0 -138000.0 -0.82 763400.0 -225426.5625 -1.29112892825146 -1.0467 -0.6717 2070158 Maybridge1_001291 [O-][N+](=O)c1cc(cc(Br)c1OC(=O)c2ccccc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C16 compound treatment 1071360.0 -25400.0 -0.12 1042080.0 -92200.0 -0.55 789460.0 -199366.5625 -1.14187047575551 -1.0475 -0.823 2070159 Maybridge1_001292 Cc1cc(OS(=O)(=O)c2ccc(F)c(Cl)c2)n(n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C17 compound treatment 1308860.0 212000.0 1.04 1265710.0 131000.0 0.78 893160.0 -95666.5625 -0.547929511679115 0.7332 0.5204 2070160 Maybridge1_001293 FC(F)(F)c1cc(Br)c2ncc(nc2c1)c3ccc(Br)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C18 compound treatment 1230450.0 134000.0 0.65 1212260.0 78000.0 0.46 937830.0 -50996.5625 -0.292082425224994 0.4762 0.5585 2070161 Maybridge1_001294 Fc1cccc(Cl)c1C(=O)NC(=O)NCC2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C19 compound treatment 1130280.0 33500.0 0.16 1091320.0 -43000.0 -0.26 934570.0 -54256.5625 -0.310754050518042 -0.2324 -0.5348 2070162 Maybridge1_001295 COCCCNC(=S)NNC(=O)c1cc(OC)c(OC)c(OC)c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C20 compound treatment 1112810.0 16100.0 0.08 1128080.0 -6230.0 -0.04 909640.0 -79186.5625 -0.453540436578065 -0.2379 -0.5152 2070163 Maybridge1_001296 Oc1cc(ccc1[N+](=O)[O-])N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C21 compound treatment 1085120.0 -11600.0 -0.06 1230730.0 96400.0 0.57 900480.0 -88346.5625 -0.506004267156076 0.0061 0.008 2070164 Maybridge1_001297 Brc1csc(/C=C\2/SC(=S)NC2=O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C22 compound treatment 1170080.0 73300.0 0.36 1231640.0 97300.0 0.58 1027690.0 38863.4375 0.222590043742262 0.6696 0.9349 2070165 Maybridge1_001298 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)C(=O)c3c(F)cccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C23 mock treatment 1181360.0 84600.0 0.41 1190490.0 56200.0 0.33 1033460.0 44633.4375 0.255637675012472 0.5792 0.9819 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 C24 mock treatment 1114780.0 18000.0 0.09 1235850.0 102000.0 0.6 947360.0 -41466.5625 -0.237499422451146 0.2624 0.4007 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D01 compound treatment 1130100.0 33400.0 0.16 922690.0 -212000.0 -1.26 849650.0 -139176.5625 -0.797132706924667 -1.0926 -0.7292 1295753 Maybridge1_001299 Cc1cc(c(C)cc1Cl)S(=O)(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D02 compound treatment 887770.0 -209000.0 -1.02 892090.0 -242000.0 -1.44 772360.0 -216466.5625 -1.23981059615769 -2.1369 -0.9905 2070166 Maybridge1_001300 CCCC1=NN(C(=O)C1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D03 compound treatment 926890.0 -170000.0 -0.83 887530.0 -247000.0 -1.47 714520.0 -274306.5625 -1.57108875779875 -2.2334 -0.9692 2070167 Maybridge1_001301 [O-][N+](=O)c1cc(ccc1NCC2CC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D04 compound treatment 1021460.0 -75300.0 -0.37 980490.0 -154000.0 -0.91 790560.0 -198266.5625 -1.13557023409221 -1.3961 -0.9283 2070168 Maybridge1_001302 CSc1ncccc1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D05 compound treatment 373390.0 -723000.0 -3.53 361410.0 -773000.0 -4.6 301760.0 -687066.5625 -3.9351685295651 -6.966 -0.9941 2070169 Maybridge1_001303 CN(C)/C=N/c1nnc(Sc2nc3c(Cl)cc(Cl)cc3s2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D06 compound treatment 1155200.0 58500.0 0.29 1380970.0 247000.0 1.47 1000020.0 11193.4375 0.0641103284482046 1.0488 0.7012 2070170 Maybridge1_001304 Clc1cc(Cl)cc(c1)S(=O)(=O)Oc2ccc(OCc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D07 compound treatment 1083330.0 -13400.0 -0.07 1243590.0 109000.0 0.65 855610.0 -133216.5625 -0.762996852094433 -0.1031 -0.1027 2070171 Maybridge1_001305 Clc1cc(Cl)cc(OS(=O)(=O)c2cccc(c2)S(=O)(=O)Oc3cc(Cl)cc(Cl)c3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D08 compound treatment 1129940.0 33200.0 0.16 1054360.0 -79900.0 -0.48 920230.0 -68596.5625 -0.392886291837766 -0.4077 -0.6392 2070172 Maybridge1_001306 CCCc1cc(O)nc(SCC(=O)Nc2ccc(F)c(Cl)c2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D09 compound treatment 1032410.0 -64300.0 -0.31 989730.0 -145000.0 -0.86 838600.0 -150226.5625 -0.860421498178709 -1.1746 -0.935 1009028 Maybridge1_001307 Clc1ccc(NC(=O)c2ccccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D10 compound treatment 1171200.0 74500.0 0.36 1037020.0 -97300.0 -0.58 782320.0 -206506.5625 -1.18276477164273 -0.8068 -0.5906 2070173 Maybridge1_001308 Cc1cc(OC(=O)c2nn(nc2C)c3ccccc3)n(n1)c4cccc(Cl)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D11 compound treatment 1032370.0 -64400.0 -0.31 1049520.0 -84800.0 -0.5 860480.0 -128346.5625 -0.735103964003285 -0.8971 -0.949 1258378 Maybridge1_001309 CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(Cl)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D12 compound treatment 1071520.0 -25200.0 -0.12 1037690.0 -96600.0 -0.57 932820.0 -56006.5625 -0.320777162255107 -0.588 -0.8784 2070174 Maybridge1_001310 FC(F)(F)c1cccc(Sc2ncccc2C(=O)Nc3ccc(Cl)cc3Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D13 compound treatment 1197460.0 101000.0 0.49 1194210.0 59900.0 0.36 898080.0 -90746.5625 -0.519750248966908 0.1897 0.2373 2070175 Maybridge1_001311 Cc1cc(SCc2c(Cl)cccc2Cl)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D14 compound treatment 1174980.0 78200.0 0.38 1104500.0 -29800.0 -0.18 830400.0 -158426.5625 -0.907386936032386 -0.4055 -0.4053 2070176 Maybridge1_001312 CN(C(=O)CSc1ccc(Cl)cc1)c2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D15 compound treatment 1197080.0 100000.0 0.49 1274880.0 141000.0 0.84 901610.0 -87216.5625 -0.499532200720142 0.4773 0.4378 2070177 Maybridge1_001313 CC(=O)NCCSc1cc(C)c(Cl)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D16 compound treatment 1118880.0 22100.0 0.11 1091630.0 -42700.0 -0.25 894730.0 -94096.5625 -0.538937348577862 -0.3952 -0.6528 2070178 Maybridge1_001314 Cc1ccc([N+](=O)[O-])c(NC(=O)NC(=O)c2c(Cl)cccc2Cl)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D17 compound treatment 895800.0 -201000.0 -0.98 955290.0 -179000.0 -1.06 727910.0 -260916.5625 -1.49439763427915 -2.0442 -0.9824 2070179 Maybridge1_001315 COc1cc(cc(Br)c1O)C2SCCS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D18 compound treatment 1232000.0 135000.0 0.66 1280370.0 146000.0 0.87 1144010.0 155183.4375 0.888811962173946 1.3962 0.9919 2070180 Maybridge1_001316 OC(=O)c1ccc(c(c1)[N+](=O)[O-])S(=O)(=O)c2cc(Cl)ccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D19 compound treatment 1314090.0 217000.0 1.06 1123010.0 -11300.0 -0.07 918490.0 -70336.5625 -0.40285212865062 0.3417 0.3004 1469626 Maybridge1_001317 OC(=O)c1cccnc1SCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D20 compound treatment 1103370.0 6630.0 0.03 1016980.0 -117000.0 -0.7 845280.0 -143546.5625 -0.822161848805225 -0.8588 -0.7961 2070181 Maybridge1_001318 CSC(=NS(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D21 compound treatment 1390920.0 294000.0 1.44 1351520.0 217000.0 1.29 1076700.0 87873.4375 0.503294447304305 1.8662 0.9345 1678057 Maybridge1_001319 CCSc1ncccc1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D22 compound treatment 1213390.0 117000.0 0.57 1177040.0 42700.0 0.25 1035730.0 46903.4375 0.268639082808551 0.6309 0.9286 2070182 Maybridge1_001320 Nc1ccccc1C(=O)NNC(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D23 mock treatment 1138400.0 41700.0 0.2 1196550.0 62200.0 0.37 965010.0 -23816.5625 -0.136409181217315 0.2525 0.5688 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 D24 mock treatment 1068810.0 -27900.0 -0.14 1126880.0 -7430.0 -0.04 1023930.0 35103.4375 0.201054672238624 0.0118 0.0478 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E01 compound treatment 566740.0 -530000.0 -2.59 616220.0 -518000.0 -3.08 536100.0 -452726.5625 -2.59298795558573 -4.7708 -0.9965 2070183 Maybridge1_001321 C/C(=N\Nc1nc(cs1)C(C)(C)C)/c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E02 compound treatment 1055680.0 -41100.0 -0.2 1117850.0 -16500.0 -0.1 942670.0 -46156.5625 -0.264361361906482 -0.3249 -0.9392 2070184 Maybridge1_001322 Nc1ccccc1C(=O)NCCCN2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E03 compound treatment 907640.0 -189000.0 -0.92 857280.0 -277000.0 -1.65 774920.0 -213906.5625 -1.22514821555947 -2.1919 -0.9736 2070185 Maybridge1_001323 CS/C(=N/N=C/c1cccs1)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E04 compound treatment 1077380.0 -19400.0 -0.09 1112840.0 -21500.0 -0.13 908080.0 -80746.5625 -0.462475324755106 -0.3953 -0.8084 1582393 Maybridge1_001324 COC(=O)c1cc(OC)c(OC)c(OC)c1NS(=O)(=O)c2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E05 compound treatment 806410.0 -290000.0 -1.42 763260.0 -371000.0 -2.21 683650.0 -305176.5625 -1.74789644884059 -3.102 -0.9841 2070186 Maybridge1_001325 CCCc1nc2cc(C)c(C)cc2nc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E06 compound treatment 1108000.0 11300.0 0.06 1110360.0 -23900.0 -0.14 883870.0 -104956.5625 -0.601137916271879 -0.3975 -0.6409 1004703 Maybridge1_001326 OC(=O)c1ccccc1I 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E07 compound treatment 1151760.0 55000.0 0.27 1114420.0 -19900.0 -0.12 782970.0 -205856.5625 -1.17904190156896 -0.5938 -0.4887 2070187 Maybridge1_001327 Cc1ccc(NC(=O)C/C(=N/O)/N)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E08 compound treatment 656980.0 -440000.0 -2.15 659900.0 -474000.0 -2.82 461310.0 -527516.5625 -3.0213471137658 -4.6136 -0.9903 2070188 Maybridge1_001328 CCOC(=O)c1cc(CC)sc1NC(=O)C(Cl)(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E09 compound treatment 1221280.0 125000.0 0.61 1286240.0 152000.0 0.9 976980.0 -11846.5625 -0.0678510969357879 0.8338 0.7639 1222255 Maybridge1_001329 Fc1ccc(NC(=O)Cc2ncon2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E10 compound treatment 1176080.0 79300.0 0.39 1110170.0 -24100.0 -0.14 837940.0 -150886.5625 -0.864201643176687 -0.358 -0.3737 1363938 Maybridge1_001330 CCOC(=O)c1c(O)c2ccccc2n(C)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E11 compound treatment 1303380.0 207000.0 1.01 1200360.0 66100.0 0.39 974520.0 -14306.5625 -0.0819407282918913 0.7624 0.7017 2070189 Maybridge1_001331 NS(=O)(=O)c1ccc(Oc2c(Cl)cccc2[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E12 compound treatment 1343060.0 246000.0 1.2 1463910.0 330000.0 1.96 973600.0 -15226.5625 -0.0872100213193771 1.7761 0.7717 2070190 Maybridge1_001332 CN(C)/C=N/c1nnc(s1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E13 compound treatment 1423310.0 327000.0 1.6 1067900.0 -66400.0 -0.39 950280.0 -38546.5625 -0.2207751445813 0.5658 0.3411 2070191 Maybridge1_001333 FC(F)(F)c1ccc2nc(cnc2c1)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E14 compound treatment 1279120.0 182000.0 0.89 1224410.0 90100.0 0.54 987000.0 -1826.5625 -0.010461622875562 0.8178 0.7865 2070192 Maybridge1_001334 Cc1cc(NC(=O)NC(=O)c2c(F)cccc2Cl)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E15 compound treatment 998470.0 -98300.0 -0.48 863260.0 -271000.0 -1.61 715940.0 -272886.5625 -1.56295571856068 -2.1101 -0.9191 2070193 Maybridge1_001335 CC(=O)OCc1csc(n1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E16 compound treatment 1248190.0 151000.0 0.74 1261670.0 127000.0 0.76 1032320.0 43493.4375 0.249108333652326 1.0083 0.927 2070194 Maybridge1_001336 CN(C)/C=N/c1nnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E17 compound treatment 1199370.0 103000.0 0.5 1171160.0 36900.0 0.22 981520.0 -7306.5625 -0.0418482813436297 0.3919 0.714 2070195 Maybridge1_001337 CC(O)CNc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E18 compound treatment 853570.0 -243000.0 -1.19 839370.0 -295000.0 -1.75 708970.0 -279856.5625 -1.6028763407363 -2.6239 -0.9878 1525564 Maybridge1_001338 Clc1cc(Cl)cc(c1)S(=O)(=O)NCC2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E19 compound treatment 1163460.0 66700.0 0.33 1215300.0 81000.0 0.48 1035610.0 46783.4375 0.267951783718009 0.621 0.9698 1055254 Maybridge1_001339 OCCNc1ccc(cn1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E20 compound treatment 1372320.0 276000.0 1.35 1171240.0 36900.0 0.22 916430.0 -72396.5625 -0.414650763038251 0.6648 0.4662 2070196 Maybridge1_001340 CC1CN(CC(C)O1)c2ccc([N+](=O)[O-])c(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E21 compound treatment 759060.0 -338000.0 -1.65 730820.0 -403000.0 -2.4 589170.0 -399656.5625 -2.28902993279369 -3.6594 -0.988 2070197 Maybridge1_001341 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/C(=N\O)/C(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E22 compound treatment 1157530.0 60800.0 0.3 1101600.0 -32700.0 -0.19 933400.0 -55426.5625 -0.317455216650822 -0.1241 -0.2605 2070198 Maybridge1_001342 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)C(=O)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E23 mock treatment 1161220.0 64500.0 0.32 1148870.0 14600.0 0.09 967520.0 -21306.5625 -0.122033175240153 0.1614 0.4629 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 E24 mock treatment 1317250.0 221000.0 1.08 1051940.0 -82400.0 -0.49 971710.0 -17116.5625 -0.0980349819954078 0.2826 0.238 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F01 compound treatment 1110140.0 13400.0 0.07 1056400.0 -77900.0 -0.46 900990.0 -87836.5625 -0.503083246021274 -0.5201 -0.7571 2070199 Maybridge1_001343 N/C(=N\O)/CS(=O)(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F02 compound treatment 1050000.0 -46700.0 -0.23 1077630.0 -56700.0 -0.34 845760.0 -143066.5625 -0.819412652443058 -0.7995 -0.8738 1573123 Maybridge1_001344 Clc1ccc(cc1)C(=O)N2CCN(CC2)C(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F03 compound treatment 1023600.0 -73100.0 -0.36 986410.0 -148000.0 -0.88 872270.0 -116556.5625 -0.66757682835757 -1.0995 -0.9474 1428169 Maybridge1_001345 Cc1cc(O)c2cc(F)cc(F)c2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F04 compound treatment 976270.0 -120000.0 -0.59 1121940.0 -12400.0 -0.07 791110.0 -197716.5625 -1.13242011326056 -1.0361 -0.8105 1002355 Maybridge1_001346 CC(=O)Nc1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F05 compound treatment 53440.0 -1040000.0 -5.1 50720.0 -1080000.0 -6.44 38400.0 -950426.5625 -5.44356093360713 -9.806 -0.995 1357459 Maybridge1_001347 Cc1cc(Sc2nnc(N)s2)c3ccccc3n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F06 compound treatment 868390.0 -228000.0 -1.12 955170.0 -179000.0 -1.07 657180.0 -331646.5625 -1.89950317322923 -2.3558 -0.9628 2070200 Maybridge1_001348 [O-][N+](=O)c1cccnc1Oc2ccc(OCc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F07 compound treatment 1142240.0 45500.0 0.22 1142890.0 8580.0 0.05 917720.0 -71106.5625 -0.407262297814929 -0.0773 -0.1656 1567712 Maybridge1_001349 Cc1cc(C)c2nc(C)cc(O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F08 compound treatment 1041670.0 -55100.0 -0.27 1039730.0 -94600.0 -0.56 807130.0 -181696.5625 -1.04066568467325 -1.0809 -0.891 1275354 Maybridge1_001350 O=C(Nc1ccccc1C(=O)NC2CCCCNC2=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F09 compound treatment 612080.0 -485000.0 -2.37 627200.0 -507000.0 -3.02 508320.0 -480506.5625 -2.75209769504612 -4.6971 -0.9952 2070201 Maybridge1_001351 Clc1ccc(/C=C/2\C(=O)ON=C2c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F10 compound treatment 1281440.0 185000.0 0.9 1075070.0 -59200.0 -0.35 875410.0 -113416.5625 -0.649592502155064 -0.0574 -0.0492 1686372 Maybridge1_001352 O=C(CC#N)NC1CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F11 compound treatment 1105620.0 8880.0 0.04 1121490.0 -12800.0 -0.08 828930.0 -159896.5625 -0.915806349891521 -0.5477 -0.5953 1741154 Maybridge1_001353 CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(F)cc2F)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F12 compound treatment 1083480.0 -13300.0 -0.06 1235360.0 101000.0 0.6 927650.0 -61176.5625 -0.350388298072609 0.1072 0.1535 2070202 Maybridge1_001354 [O-][N+](=O)c1ccc(cc1OC(=O)c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F13 compound treatment 1203780.0 107000.0 0.52 1222660.0 88400.0 0.53 900580.0 -88246.5625 -0.505431517913958 0.3135 0.3494 2070203 Maybridge1_001355 Cc1cc(SCc2cccc(F)c2)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F14 compound treatment 930090.0 -167000.0 -0.81 997940.0 -136000.0 -0.81 777050.0 -211776.5625 -1.21294865670235 -1.6386 -0.9807 2070204 Maybridge1_001356 Clc1ccc(cc1)C(=O)Nc2ncccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F15 compound treatment 43320.0 -1050000.0 -5.15 43230.0 -1090000.0 -6.49 34570.0 -954256.5625 -5.46549722958025 -9.873 -0.995 2070205 Maybridge1_001357 Clc1cn[nH]c(=O)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F16 compound treatment 1033600.0 -63100.0 -0.31 985830.0 -148000.0 -0.88 723560.0 -265266.5625 -1.51931222631128 -1.565 -0.8772 2070206 Maybridge1_001358 OC(=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F17 compound treatment 939720.0 -157000.0 -0.77 1136090.0 1780.0 0.01 893780.0 -95046.5625 -0.544378466377983 -0.7511 -0.7984 2070207 Maybridge1_001359 CCOC(=O)CC(=O)CSc1cc(C)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F18 compound treatment 1126490.0 29800.0 0.15 1123300.0 -11000.0 -0.07 874920.0 -113906.5625 -0.652398973441442 -0.3305 -0.4921 1863471 Maybridge1_001360 OC(=O)c1ccc(Sc2ccccn2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F19 compound treatment 1142830.0 46100.0 0.23 1338290.0 204000.0 1.21 825940.0 -162886.5625 -0.93293155223085 0.2917 0.1886 2070208 Maybridge1_001361 CN(C)/C=C\1/C(=O)NN=C1CSc2cc(C)c(Cl)cc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F20 compound treatment 770600.0 -326000.0 -1.59 884580.0 -250000.0 -1.49 740000.0 -248826.5625 -1.42515225090708 -2.6002 -0.9989 2070209 Maybridge1_001362 FC(F)(F)c1cc(c2cccs2)n(n1)c3ccc(cc3)S(=O)(=O)NC(=S)Nc4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F21 compound treatment 1117400.0 20700.0 0.1 1159130.0 24800.0 0.15 1091860.0 103033.4375 0.590123232409397 0.4842 0.7853 1783937 Maybridge1_001363 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F22 compound treatment 1359040.0 262000.0 1.28 1453310.0 319000.0 1.9 1113920.0 125093.4375 0.716471715220633 2.2488 0.9375 2070210 Maybridge1_001364 COc1ccc(Br)c(c1)C(=O)NNC(=O)c2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F23 mock treatment 1105360.0 8620.0 0.04 1204500.0 70200.0 0.42 965070.0 -23756.5625 -0.136065531672045 0.1868 0.4234 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 F24 mock treatment 1080700.0 -16000.0 -0.08 1109640.0 -24700.0 -0.15 976030.0 -12796.5625 -0.0732922147359092 -0.1722 -0.9478 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G01 compound treatment 771650.0 -325000.0 -1.59 800580.0 -334000.0 -1.98 705170.0 -283656.5625 -1.62464081193679 -3.0008 -0.9947 2070211 Maybridge1_001365 CS/C(=N/N=C/c1ccc(Cl)cc1)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G02 compound treatment 1090450.0 -6290.0 -0.03 1072000.0 -62300.0 -0.37 903320.0 -85506.5625 -0.489738188679924 -0.5144 -0.8366 2070212 Maybridge1_001366 NS(=O)(=O)c1cc(Cl)cc(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G03 compound treatment 963800.0 -133000.0 -0.65 967570.0 -167000.0 -0.99 798650.0 -190176.5625 -1.08923482040486 -1.5763 -0.9792 2070213 Maybridge1_001367 [O-][N+](=O)c1ccc(Oc2ccc(cc2)c3ccc(Oc4ccc(cn4)[N+](=O)[O-])cc3)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G04 compound treatment 963600.0 -133000.0 -0.65 1018300.0 -116000.0 -0.69 803810.0 -185016.5625 -1.05968095951157 -1.3856 -0.9745 1737783 Maybridge1_001368 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c2cc3ccccc3oc2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G05 compound treatment 1106830.0 10100.0 0.05 1101800.0 -32500.0 -0.19 816450.0 -172376.5625 -0.987285455307851 -0.6531 -0.6484 2070214 Maybridge1_001369 [O-][N+](=O)c1cc(ccc1Oc2ccc(F)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G06 compound treatment 1102440.0 5700.0 0.03 1052600.0 -81700.0 -0.49 868960.0 -119866.5625 -0.686534828271677 -0.6608 -0.7852 2070215 Maybridge1_001370 CN(C)/C=N/c1cc(C)on1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G07 compound treatment 1123270.0 26500.0 0.13 1272000.0 138000.0 0.82 877730.0 -111096.5625 -0.636304719737926 0.1802 0.1724 2070216 Maybridge1_001371 CSc1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G08 compound treatment 968080.0 -129000.0 -0.63 973710.0 -161000.0 -0.96 818570.0 -170256.5625 -0.975143171374949 -1.4773 -0.9831 1380289 Maybridge1_001372 Cc1nn(nc1C(=O)Nc2nnc(s2)C3CC3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G09 compound treatment 82750.0 -1010000.0 -4.95 141360.0 -993000.0 -5.9 104020.0 -884806.5625 -5.06772288092928 -9.1952 -0.9968 2070217 Maybridge1_001373 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(Cl)cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G10 compound treatment 1083390.0 -13300.0 -0.07 963420.0 -171000.0 -1.02 754150.0 -234676.5625 -1.34410823314738 -1.4004 -0.8304 2070218 Maybridge1_001374 CSC(=S)Nc1ccc(F)cc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G11 compound treatment 415520.0 -681000.0 -3.33 437600.0 -697000.0 -4.14 248570.0 -740256.5625 -4.23981385144768 -6.7614 -0.9946 2070219 Maybridge1_001375 FC(F)(F)c1ccc2nc3C(=O)c4ccccc4-c3nc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G12 compound treatment 1100990.0 4250.0 0.02 1227220.0 92900.0 0.55 1124750.0 135923.4375 0.778500458142015 0.7805 0.8174 2070220 Maybridge1_001376 CN(C)/C=N/c1nnc(C)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G13 compound treatment 1386880.0 290000.0 1.42 1231370.0 97100.0 0.58 889120.0 -99706.5625 -0.571068581060683 0.822 0.5032 1052629 Maybridge1_001377 COc1cc(C(=O)O)c([N+](=O)[O-])c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G14 compound treatment 1070120.0 -26600.0 -0.13 1004810.0 -129000.0 -0.77 787330.0 -201496.5625 -1.15407003461262 -1.186 -0.8511 2070221 Maybridge1_001378 Cc1onc(NC(=O)NC(=O)c2c(F)cccc2Cl)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G15 compound treatment 108530.0 -988000.0 -4.83 457000.0 -677000.0 -4.03 370150.0 -618676.5625 -3.54346532288059 -7.1588 -0.9919 2070222 Maybridge1_001379 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(cc2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G16 compound treatment 277180.0 -820000.0 -4.0 242340.0 -892000.0 -5.3 179640.0 -809186.5625 -4.63460990403963 -8.05 -0.9935 2070223 Maybridge1_001380 CN(C)/C=N/c1nnc(Sc2ccc(cn2)[N+](=O)[O-])s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G17 compound treatment 1001890.0 -94800.0 -0.46 964830.0 -169000.0 -1.01 775740.0 -213086.5625 -1.2204516717741 -1.554 -0.9423 1500459 Maybridge1_001381 COc1cc2c(=O)n(CC=C)c(=S)[nH]c2c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G18 compound treatment 755630.0 -341000.0 -1.67 778880.0 -355000.0 -2.11 625060.0 -363766.5625 -2.08347022979754 -3.3854 -0.9946 1441622 Maybridge1_001382 Cc1cc(c(C)cc1Cl)S(=O)(=O)NCC2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G19 compound treatment 1183040.0 86300.0 0.42 1119590.0 -14700.0 -0.09 906000.0 -82826.5625 -0.474388508991161 -0.081 -0.1264 2070224 Maybridge1_001383 [O-][N+](=O)c1ccc(o1)C(=O)OCCNc2ccc(cn2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G20 compound treatment 1103070.0 6330.0 0.03 1064250.0 -70100.0 -0.42 841350.0 -147476.5625 -0.844670894020463 -0.7103 -0.7538 2070225 Maybridge1_001384 Oc1cc(ccc1[N+](=O)[O-])N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G21 compound treatment 1217130.0 120000.0 0.59 1226210.0 91900.0 0.55 873490.0 -115336.5625 -0.66058928760373 0.2737 0.2633 2070226 Maybridge1_001385 CC(C)c1ccc(cc1)S(=O)(=O)Oc2cccc3ccc(C)nc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G22 compound treatment 1051380.0 -45400.0 -0.22 1182240.0 47900.0 0.29 992800.0 3973.4375 0.0227578331672833 0.0498 0.1376 2070227 Maybridge1_001386 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(F)cc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G23 mock treatment 1090680.0 -6060.0 -0.03 1085130.0 -49200.0 -0.29 977570.0 -11256.5625 -0.0644718764072916 -0.2231 -0.7415 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 G24 mock treatment 1124050.0 27300.0 0.13 1203910.0 69600.0 0.41 985410.0 -3416.5625 -0.0195683358252386 0.3047 0.7 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H01 compound treatment 1048260.0 -48500.0 -0.24 1077690.0 -56600.0 -0.34 805370.0 -183456.5625 -1.05074607133453 -0.9378 -0.831 2070228 Maybridge1_001387 Cc1cc(C)n(n1)c2ccc(Sc3ccc(Cl)cc3)nn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H02 compound treatment 886440.0 -210000.0 -1.03 878880.0 -255000.0 -1.52 725150.0 -263676.5625 -1.51020551336161 -2.3421 -0.9859 2070229 Maybridge1_001388 CC/1=NN(C(=O)\C1=C/c2cc(Br)cs2)c3cccc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H03 compound treatment 928000.0 -169000.0 -0.82 956880.0 -177000.0 -1.06 802880.0 -185946.5625 -1.06500752746327 -1.7 -0.9936 2070230 Maybridge1_001389 Cc1nn(c2ccccc2)c3oc(=O)cc(C)c13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H04 compound treatment 976680.0 -120000.0 -0.59 1004370.0 -130000.0 -0.77 734240.0 -254586.5625 -1.45814260725308 -1.6266 -0.9288 2070231 Maybridge1_001390 [O-][N+](=O)c1ccc(Oc2ccc(cc2)C3SCCS3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H05 compound treatment 1089930.0 -6810.0 -0.03 1193180.0 58900.0 0.35 1124110.0 135283.4375 0.77483486299246 0.6303 0.7407 2070232 Maybridge1_001391 Cc1n[nH]c2oc(=O)cc(C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H06 compound treatment 1026510.0 -70200.0 -0.34 974210.0 -160000.0 -0.95 729040.0 -259786.5625 -1.48792556784321 -1.6068 -0.8929 2070233 Maybridge1_001392 [O-][N+](=O)c1ccc(Oc2ccc(OCc3ccccc3)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H07 compound treatment 1208760.0 112000.0 0.55 1150600.0 16300.0 0.1 951040.0 -37786.5625 -0.216422250341203 0.247 0.4141 1033256 Maybridge1_001393 CC1=NN(C(=O)CC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H08 compound treatment 599610.0 -497000.0 -2.43 521720.0 -613000.0 -3.64 415960.0 -572866.5625 -3.28108889506632 -5.3998 -0.9869 1408705 Maybridge1_001394 O=C(Nc1ccccc1C(=O)NC2CCCCNC2=O)c3cc4ccccc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H09 compound treatment 655590.0 -441000.0 -2.16 517210.0 -617000.0 -3.67 440990.0 -547836.5625 -3.13772975976418 -5.1746 -0.9787 2070234 Maybridge1_001395 CC/1=NN(C(=O)\C1=C/c2ccc(Cl)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H10 compound treatment 974140.0 -123000.0 -0.6 938910.0 -195000.0 -1.16 775770.0 -213056.5625 -1.22027984700146 -1.7212 -0.9625 2070235 Maybridge1_001396 Cc1nn(nc1c2nnc(o2)c3ccc(Cl)cc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H11 compound treatment 1351790.0 255000.0 1.25 1523760.0 389000.0 2.32 1106210.0 117383.4375 0.672312748653333 2.4447 0.9006 2070236 Maybridge1_001397 CCOC(=O)Cc1csc(N/C=N/O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H12 compound treatment 54260.0 -1040000.0 -5.09 58150.0 -1080000.0 -6.4 46600.0 -942226.5625 -5.39659549575345 -9.7511 -0.9951 2070237 Maybridge1_001398 [O-][N+](=O)c1cc2ccccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H13 compound treatment 1052260.0 -44500.0 -0.22 1063100.0 -71200.0 -0.42 847000.0 -141826.5625 -0.812310561840795 -0.8389 -0.8911 2070238 Maybridge1_001399 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Cc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H14 compound treatment 1038100.0 -58600.0 -0.29 1259640.0 125000.0 0.75 1039800.0 50973.4375 0.291949976962754 0.4335 0.5098 1441513 Maybridge1_001400 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H15 compound treatment 733720.0 -363000.0 -1.77 992530.0 -142000.0 -0.84 648880.0 -339946.5625 -1.94704136032502 -2.6349 -0.9528 2070239 Maybridge1_001401 Cc1cc(SCC#N)c(C)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H16 compound treatment 1034300.0 -62400.0 -0.31 1019930.0 -114000.0 -0.68 750890.0 -237936.5625 -1.36277985844043 -1.3556 -0.8727 2070240 Maybridge1_001402 Clc1ccc(cc1)C(=O)Nc2cnccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H17 compound treatment 951690.0 -145000.0 -0.71 919230.0 -215000.0 -1.28 651740.0 -337086.5625 -1.93066073200045 -2.2622 -0.9341 2070241 Maybridge1_001403 Cc1cc(SCC2=NNC(=O)C2)c(C)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H18 compound treatment 574610.0 -522000.0 -2.55 741830.0 -392000.0 -2.33 581460.0 -407366.5625 -2.33318889936099 -4.1674 -0.9991 2070242 Maybridge1_001404 Cc1nn(c2cccc(Cl)c2)c3oc(=O)cc(c13)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H19 compound treatment 1118580.0 21800.0 0.11 1554310.0 420000.0 2.5 881760.0 -107066.5625 -0.61322292528057 1.1495 0.4466 1030549 Maybridge1_001405 O=C1N(CC#N)S(=O)(=O)c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H20 compound treatment 1393380.0 297000.0 1.45 1285620.0 151000.0 0.9 981310.0 -7516.5625 -0.0430510547520775 1.3314 0.7802 2070243 Maybridge1_001406 NS(=O)(=O)c1cc(Cl)sc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H21 compound treatment 1197120.0 100000.0 0.49 1324290.0 190000.0 1.13 951310.0 -37516.5625 -0.214875827387485 0.8114 0.649 2070244 Maybridge1_001407 CCCC(=O)c1cc2cc(ccc2oc1=O)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H22 compound treatment 1107390.0 10700.0 0.05 1426180.0 292000.0 1.74 1104970.0 116143.4375 0.66521065805107 1.4162 0.7616 2070245 Maybridge1_001408 COc1cccc(c1)C(=O)NNC(=O)c2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H23 mock treatment 1064490.0 -32200.0 -0.16 1186730.0 52400.0 0.31 1000510.0 11683.4375 0.0669167997345829 0.1277 0.3589 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 H24 mock treatment 1096000.0 -736.0 0.0 1225570.0 91300.0 0.54 1020890.0 32063.4375 0.183643095278236 0.4173 0.7283 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I01 compound treatment 885300.0 -211000.0 -1.03 822960.0 -311000.0 -1.85 762560.0 -226266.5625 -1.29594002188525 -2.4136 -0.9713 2070246 Maybridge1_001409 CS/C(=N/N=C/c1c(F)cccc1Cl)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I02 compound treatment 994140.0 -103000.0 -0.5 1050270.0 -84000.0 -0.5 846680.0 -142146.5625 -0.814143359415572 -1.048 -0.9714 2070247 Maybridge1_001410 CC(=O)C(C)(C)OC(=O)N1CCOCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I03 compound treatment 1053760.0 -43000.0 -0.21 1058430.0 -75900.0 -0.45 859160.0 -129666.5625 -0.742664253999243 -0.8105 -0.9066 1019766 Maybridge1_001411 CC(=O)Nc1ccc(C)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I04 compound treatment 1023360.0 -73400.0 -0.36 1063800.0 -70500.0 -0.42 777760.0 -211066.5625 -1.20888213708331 -1.147 -0.8632 1658637 Maybridge1_001412 CC1CN(CC(C)O1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I05 compound treatment 896560.0 -200000.0 -0.98 948730.0 -186000.0 -1.1 791400.0 -197426.5625 -1.13075914045842 -1.8546 -0.9981 2070248 Maybridge1_001413 Cc1cccc(Cl)c1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I06 compound treatment 401330.0 -695000.0 -3.4 368740.0 -766000.0 -4.55 268370.0 -720456.5625 -4.12640950150831 -6.9724 -0.9931 1442310 Maybridge1_001414 Clc1ccc(cc1Cl)C(=O)CSC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I07 compound treatment 625220.0 -472000.0 -2.3 567290.0 -567000.0 -3.37 426140.0 -562686.5625 -3.22278302221871 -5.1375 -0.9876 2070249 Maybridge1_001415 COC(=O)c1sc2ccccc2c1OS(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I08 compound treatment 837490.0 -259000.0 -1.27 950130.0 -184000.0 -1.1 729650.0 -259176.5625 -1.48443179746629 -2.2207 -0.9924 2070250 Maybridge1_001416 Cc1nnc(NC(=O)c2nn(nc2C)c3ccccc3)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I09 compound treatment 1124850.0 28100.0 0.14 1103920.0 -30400.0 -0.18 830840.0 -157986.5625 -0.904866839367067 -0.5474 -0.5868 2070251 Maybridge1_001417 Cc1cccc(C)c1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I10 compound treatment 1201460.0 105000.0 0.51 1100480.0 -33800.0 -0.2 875640.0 -113186.5625 -0.648275178898193 -0.195 -0.2294 1165063 Maybridge1_001418 Nc1nc(=O)c2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I11 compound treatment 961010.0 -136000.0 -0.66 910620.0 -224000.0 -1.33 597860.0 -390966.5625 -2.23925802365364 -2.4437 -0.9092 2070252 Maybridge1_001419 N/C(=N\OC(=O)c1cccs1)/CC(=O)Nc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I12 compound treatment 919950.0 -177000.0 -0.86 914140.0 -220000.0 -1.31 731730.0 -257096.5625 -1.47251861323024 -2.1047 -0.9783 2070253 Maybridge1_001420 Cc1nnc(N/C=N/O)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I13 compound treatment 1374570.0 278000.0 1.36 1177460.0 43200.0 0.26 893240.0 -95586.5625 -0.547471312285421 0.6158 0.4144 2070254 Maybridge1_001421 NC(=O)NCc1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I14 compound treatment 998990.0 -97700.0 -0.48 984640.0 -150000.0 -0.89 764480.0 -224346.5625 -1.28494323643659 -1.5314 -0.937 2070255 Maybridge1_001422 Cc1onc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I15 compound treatment 547750.0 -549000.0 -2.68 720820.0 -413000.0 -2.46 426980.0 -561846.5625 -3.21797192858492 -4.8261 -0.9935 2070256 Maybridge1_001423 CC(C)(C)c1ccc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I16 compound treatment 981400.0 -115000.0 -0.56 918170.0 -216000.0 -1.29 694050.0 -294776.5625 -1.68833052766031 -2.0422 -0.9302 2070257 Maybridge1_001424 CN(C)/C=N/c1nnc(Sc2ncccc2[N+](=O)[O-])s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I17 compound treatment 1025230.0 -71500.0 -0.35 929970.0 -204000.0 -1.22 761200.0 -227626.5625 -1.30372941157806 -1.656 -0.9118 2070258 Maybridge1_001425 OCCNc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I18 compound treatment 1120960.0 24200.0 0.12 1197190.0 62900.0 0.37 908000.0 -80826.5625 -0.4629335241488 0.0169 0.0279 1236124 Maybridge1_001426 S=C1NCN(CC2CC2)CN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I19 compound treatment 1129380.0 32600.0 0.16 1097340.0 -37000.0 -0.22 918720.0 -70106.5625 -0.401534805393748 -0.2667 -0.5501 1158168 Maybridge1_001427 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I20 compound treatment 1080160.0 -16600.0 -0.08 1099450.0 -34900.0 -0.21 840280.0 -148546.5625 -0.850799310911126 -0.6576 -0.7478 1229472 Maybridge1_001428 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Nc2ccccc2C(=O)NCC3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I21 compound treatment 1186660.0 89900.0 0.44 1075730.0 -58600.0 -0.35 793730.0 -195096.5625 -1.11741408311707 -0.5926 -0.474 1694034 Maybridge1_001429 CN1C(NC(=O)c2ccccc12)c3cc(Br)cs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I22 compound treatment 1223710.0 127000.0 0.62 1218920.0 84600.0 0.5 950100.0 -38726.5625 -0.221806093217113 0.5206 0.628 2070259 Maybridge1_001430 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(F)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I23 mock treatment 1048810.0 -47900.0 -0.23 1090920.0 -43400.0 -0.26 954400.0 -34426.5625 -0.197177875806038 -0.398 -0.9941 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 I24 mock treatment 1113540.0 16800.0 0.08 1127140.0 -7170.0 -0.04 1013540.0 24713.4375 0.141546025982561 0.1045 0.6181 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J01 compound treatment 867280.0 -229000.0 -1.12 825320.0 -309000.0 -1.84 687300.0 -301526.5625 -1.72699110150328 -2.7052 -0.9803 2070260 Maybridge1_001431 Nc1ccc(Cl)cc1C(=O)N2CCN(CC2)c3ccc(cn3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J02 compound treatment 955320.0 -141000.0 -0.69 1019160.0 -115000.0 -0.68 897000.0 -91826.5625 -0.525935940781783 -1.0979 -0.9928 2070261 Maybridge1_001432 Oc1cc(Sc2ccccc2)ccc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J03 compound treatment 966160.0 -131000.0 -0.64 997170.0 -137000.0 -0.82 799140.0 -189686.5625 -1.08642834911848 -1.4664 -0.9771 2070262 Maybridge1_001433 Cc1nn(C)c2oc(=O)cc(c12)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J04 compound treatment 1010810.0 -85900.0 -0.42 1060580.0 -73700.0 -0.44 867890.0 -120936.5625 -0.692663245162339 -0.8954 -0.9722 1021654 Maybridge1_001434 CC(=O)Nc1ccc(cc1C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J05 compound treatment 971610.0 -125000.0 -0.61 877360.0 -257000.0 -1.53 748700.0 -240126.5625 -1.37532306684281 -2.0292 -0.9461 2070263 Maybridge1_001435 CC1CCN(CC1)c2ccc([N+](=O)[O-])c(Oc3nc4c(Cl)cc(Cl)cc4s3)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J06 compound treatment 1031810.0 -64900.0 -0.32 1032160.0 -102000.0 -0.61 734970.0 -253856.5625 -1.45396153778562 -1.3733 -0.8544 2070264 Maybridge1_001436 [O-][N+](=O)c1ccc(Oc2ccc(OCc3ccccc3)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J07 compound treatment 1006040.0 -90700.0 -0.44 1159520.0 25200.0 0.15 989320.0 493.4375 0.00282615954157612 -0.1676 -0.3584 2070265 Maybridge1_001437 Clc1ccc(I)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J08 compound treatment 929070.0 -168000.0 -0.82 955850.0 -178000.0 -1.06 787360.0 -201466.5625 -1.15389820983998 -1.7519 -0.9904 1424245 Maybridge1_001438 Clc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NC3CCCCNC3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J09 compound treatment 880640.0 -216000.0 -1.06 915730.0 -219000.0 -1.3 756840.0 -231986.5625 -1.3287012785344 -2.1271 -0.9951 2070266 Maybridge1_001439 Cc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J10 compound treatment 993230.0 -104000.0 -0.51 1062980.0 -71300.0 -0.42 768520.0 -220306.5625 -1.26180416705502 -1.2654 -0.8886 2070267 Maybridge1_001440 Cc1nn(nc1c2nnc(o2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J11 compound treatment 1027440.0 -69300.0 -0.34 1072670.0 -61600.0 -0.37 820220.0 -168606.5625 -0.965692808880001 -0.9646 -0.8874 2070268 Maybridge1_001441 Cc1ccc2cc(ccc2n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J12 compound treatment 1272450.0 176000.0 0.86 1190530.0 56200.0 0.33 889820.0 -99006.5625 -0.567059336365857 0.3613 0.334 2070269 Maybridge1_001442 Clc1ccc(NC(=O)CC#N)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J13 compound treatment 1250490.0 154000.0 0.75 1456430.0 322000.0 1.92 1076100.0 87273.4375 0.499857951851597 1.8282 0.8634 1013980 Maybridge1_001443 OS(=O)(=O)c1cccc2cccc(Cl)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J14 compound treatment 1277030.0 180000.0 0.88 1374680.0 240000.0 1.43 866760.0 -122066.5625 -0.699135311598273 0.9302 0.5114 2070270 Maybridge1_001444 O=C(CC#N)Nc1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J15 compound treatment 1234490.0 138000.0 0.67 1436840.0 303000.0 1.8 1007200.0 18373.4375 0.105233724032279 1.488 0.7735 2070271 Maybridge1_001445 CSc1ncccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J16 compound treatment 1253640.0 157000.0 0.77 1013120.0 -121000.0 -0.72 704480.0 -284346.5625 -1.6285927817074 -0.9137 -0.4713 1160934 Maybridge1_001446 Clc1ccc(NC(=O)c2cnccn2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J17 compound treatment 1026660.0 -70100.0 -0.34 1060320.0 -74000.0 -0.44 804570.0 -184256.5625 -1.05532806527147 -1.061 -0.8889 2070272 Maybridge1_001447 O=C1CC(=NN1)CSc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J18 compound treatment 995920.0 -101000.0 -0.49 919220.0 -215000.0 -1.28 715240.0 -273586.5625 -1.5669649632555 -1.9275 -0.9259 2070273 Maybridge1_001448 Cc1nn(c2ccccc2)c3oc(=O)cc(c13)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J19 compound treatment 1141600.0 44900.0 0.22 1382880.0 249000.0 1.48 1029990.0 41163.4375 0.235763276310976 1.1161 0.7378 1234815 Maybridge1_001449 CCSc1ncccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J20 compound treatment 1238820.0 142000.0 0.69 1393010.0 259000.0 1.54 1059200.0 70373.4375 0.403063329933651 1.5217 0.8769 1422595 Maybridge1_001450 Fc1cccc(Cl)c1CN2c3ccccc3C(=O)CS2(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J21 compound treatment 1200550.0 104000.0 0.51 1348660.0 214000.0 1.27 1098810.0 109983.4375 0.6299293047366 1.3925 0.9224 1531298 Maybridge1_001451 CCCC(=O)c1cc2cc(Br)cc(Br)c2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J22 compound treatment 1093360.0 -3380.0 -0.02 1228720.0 94400.0 0.56 945510.0 -43316.5625 -0.24809528343033 0.1714 0.2791 1487398 Maybridge1_001452 Fc1ccc(cc1F)C(=O)c2cc3ccccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J23 mock treatment 1093700.0 -3040.0 -0.01 1242280.0 108000.0 0.64 949760.0 -39066.5625 -0.223753440640314 0.2329 0.3425 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 J24 mock treatment 1118030.0 21300.0 0.1 1091260.0 -43000.0 -0.26 944600.0 -44226.5625 -0.253307301533604 -0.234 -0.6242 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K01 compound treatment 844640.0 -252000.0 -1.23 838330.0 -296000.0 -1.76 744640.0 -244186.5625 -1.3985766860728 -2.5348 -0.9888 2070274 Maybridge1_001453 CS/C(=N/N=C/c1ccc(cc1)N(C)C)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K02 compound treatment 1011000.0 -85700.0 -0.42 1015130.0 -119000.0 -0.71 860930.0 -127896.5625 -0.732526592413754 -1.0739 -0.9746 2070275 Maybridge1_001454 Clc1ccc2[nH]c(nc(=O)c2c1)c3cc(Br)cs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K03 compound treatment 916500.0 -180000.0 -0.88 804010.0 -330000.0 -1.96 747150.0 -241676.5625 -1.38420068009564 -2.4416 -0.9541 1143063 Maybridge1_001455 COc1ccc(Oc2cc(C)nc3ccccc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K04 compound treatment 1011480.0 -85300.0 -0.42 1027840.0 -106000.0 -0.63 817190.0 -171636.5625 -0.983047110916177 -1.1736 -0.9455 2070276 Maybridge1_001456 O=C(CC#N)N1CCSCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K05 compound treatment 1024530.0 -72200.0 -0.35 1006030.0 -128000.0 -0.76 792450.0 -196376.5625 -1.12474527341618 -1.2935 -0.9212 1037135 Maybridge1_001457 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K06 compound treatment 635750.0 -461000.0 -2.25 668730.0 -466000.0 -2.77 564510.0 -424316.5625 -2.4302698959 -4.3019 -0.9963 2070277 Maybridge1_001458 Cc1onc(NC(=O)c2ccc(o2)[N+](=O)[O-])c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K07 compound treatment 499840.0 -597000.0 -2.92 530290.0 -604000.0 -3.59 421030.0 -567796.5625 -3.25205050849094 -5.6351 -0.9964 2070278 Maybridge1_001459 COC(=O)c1sc2ccccc2c1OS(=O)(=O)c3ccc(OC)c(OC)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K08 compound treatment 959650.0 -137000.0 -0.67 932570.0 -202000.0 -1.2 738720.0 -250106.5625 -1.43248344120619 -1.9064 -0.9604 1403130 Maybridge1_001460 CCc1nnc(NC(=O)c2nn(nc2C)c3ccccc3)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K09 compound treatment 132960.0 -964000.0 -4.71 494880.0 -639000.0 -3.8 371680.0 -617146.5625 -3.53470225947618 -6.9547 -0.9923 2070279 Maybridge1_001461 CSc1ccc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K10 compound treatment 952380.0 -144000.0 -0.71 940870.0 -193000.0 -1.15 788820.0 -200006.5625 -1.14553607090506 -1.7327 -0.9789 2070280 Maybridge1_001462 CC(=O)c1cc2cc(Br)ccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K11 compound treatment 894580.0 -202000.0 -0.99 823520.0 -311000.0 -1.85 649810.0 -339016.5625 -1.94171479237332 -2.7583 -0.9655 2070281 Maybridge1_001463 COc1ccc(OC)c2nc3-c4ccccc4C(=O)c3nc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K12 compound treatment 1270560.0 174000.0 0.85 1212910.0 78600.0 0.47 854250.0 -134576.5625 -0.770786241787238 0.3152 0.2545 1537115 Maybridge1_001464 Fc1ccc(NC(=O)Cc2nn[nH]n2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K13 compound treatment 718800.0 -378000.0 -1.85 730790.0 -404000.0 -2.4 596960.0 -391866.5625 -2.2444127668327 -3.7473 -0.9943 2070282 Maybridge1_001465 CC(=O)C1=CN=C(SC1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K14 compound treatment 1050780.0 -46000.0 -0.22 1076450.0 -57900.0 -0.34 874110.0 -114716.5625 -0.657038242302598 -0.7076 -0.9132 2070283 Maybridge1_001466 COC(=O)CS(=O)(=O)c1cc(C)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K15 compound treatment 1109440.0 12700.0 0.06 1102290.0 -32000.0 -0.19 1029280.0 40453.4375 0.231696756691938 0.0597 0.1949 1046920 Maybridge1_001467 COC(=O)c1cc(OC)c(OC)c(OC)c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K16 compound treatment 1066290.0 -30400.0 -0.15 937610.0 -197000.0 -1.17 815880.0 -172946.5625 -0.990550125987923 -1.3331 -0.8657 2070284 Maybridge1_001468 CCc1ccc(cc1)c2ccc(OC(=O)c3c(Br)cc(cc3[N+](=O)[O-])C(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K17 compound treatment 828270.0 -268000.0 -1.31 848730.0 -286000.0 -1.7 661350.0 -327476.5625 -1.8756195298329 -2.8206 -0.9897 2070285 Maybridge1_001469 CC(C)(CO)Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K18 compound treatment 1051800.0 -44900.0 -0.22 1078080.0 -56200.0 -0.33 825500.0 -163326.5625 -0.93545164889617 -0.8599 -0.8452 1162688 Maybridge1_001470 Fc1ccc(cc1Cl)S(=O)(=O)NCC2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K19 compound treatment 1224520.0 128000.0 0.62 1122650.0 -11700.0 -0.07 886480.0 -102346.5625 -0.586189161052599 -0.018 -0.021 2070286 Maybridge1_001471 OC(=O)CSc1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K20 compound treatment 1305240.0 209000.0 1.02 1235690.0 101000.0 0.6 1039860.0 51033.4375 0.292293626508025 1.105 0.9062 2070287 Maybridge1_001472 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)Nc2ccccc2C(=O)NCC3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K21 compound treatment 682880.0 -414000.0 -2.02 674900.0 -459000.0 -2.73 516220.0 -472606.5625 -2.70685050491879 -4.3075 -0.9914 1227697 Maybridge1_001473 Brc1csc(c1)C2NC(=O)c3ccccc3N2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K22 compound treatment 1256280.0 160000.0 0.78 1385890.0 252000.0 1.5 983570.0 -5256.5625 -0.0301069218802102 1.2964 0.7684 2070288 Maybridge1_001474 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K23 mock treatment 1062360.0 -34400.0 -0.17 1134240.0 -67.8 0.0 988990.0 163.4375 9.36087042586644E-4 -0.0967 -0.5755 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 K24 mock treatment 1133480.0 36700.0 0.18 1101540.0 -32800.0 -0.19 946720.0 -42106.5625 -0.241165017600702 -0.1481 -0.4133 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L01 compound treatment 1021290.0 -75400.0 -0.37 920110.0 -214000.0 -1.27 911170.0 -77656.5625 -0.444777373173659 -1.205 -0.8616 2070289 Maybridge1_001475 Nc1ccccc1C(=O)N2CCN(CC2)c3ccc(cn3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L02 compound treatment 985730.0 -111000.0 -0.54 927770.0 -207000.0 -1.23 837680.0 -151146.5625 -0.865690791206194 -1.522 -0.9528 2070290 Maybridge1_001476 Cc1cc(Sc2ccc([N+](=O)[O-])c(O)c2)c(C)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L03 compound treatment 992110.0 -105000.0 -0.51 1118270.0 -16000.0 -0.1 956900.0 -31926.5625 -0.182859144753087 -0.4558 -0.8268 1174018 Maybridge1_001477 Cc1nc2ccc(Cl)cc2c(O)c1I 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L04 compound treatment 987920.0 -109000.0 -0.53 994620.0 -140000.0 -0.83 828390.0 -160436.5625 -0.918899195798959 -1.3171 -0.9771 2070291 Maybridge1_001478 N#Cc1cccnc1Sc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L05 compound treatment 931470.0 -165000.0 -0.81 1070910.0 -63400.0 -0.38 803300.0 -185526.5625 -1.06260198064637 -1.2973 -0.9355 2070292 Maybridge1_001479 Cc1cc(C)n(n1)c2ccc(Sc3ccccn3)nn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L06 compound treatment 1013010.0 -83700.0 -0.41 1024270.0 -110000.0 -0.65 719700.0 -269126.5625 -1.54142034705704 -1.5039 -0.8724 2070293 Maybridge1_001480 COc1cc(cc(Br)c1OS(=O)(=O)c2ccc(C)cc2)C3SCCS3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L07 compound treatment 805020.0 -292000.0 -1.43 1023720.0 -111000.0 -0.66 741920.0 -246906.5625 -1.41415546545841 -2.019 -0.9556 2070294 Maybridge1_001481 CN(C)/C=C/1\C(=NN(C1=O)c2ccccc2)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L08 compound treatment 958910.0 -138000.0 -0.67 1066730.0 -67600.0 -0.4 905170.0 -83656.5625 -0.47914232770074 -0.8974 -0.9765 2070295 Maybridge1_001482 COc1cc(Sc2ccc(Cl)cc2)ccc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L09 compound treatment 745340.0 -351000.0 -1.72 800170.0 -334000.0 -1.99 625070.0 -363756.5625 -2.08341295487332 -3.3413 -0.9968 2070296 Maybridge1_001483 Fc1cccc(NC(=O)c2cccc(Cl)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L10 compound treatment 1191960.0 95200.0 0.47 1044960.0 -89300.0 -0.53 857300.0 -131526.5625 -0.753317389902638 -0.4731 -0.4581 1412717 Maybridge1_001484 Fc1ccccc1NC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L11 compound treatment 988120.0 -109000.0 -0.53 898080.0 -236000.0 -1.4 707220.0 -281606.5625 -1.61289945247337 -2.0486 -0.9296 2070297 Maybridge1_001485 Cc1cc(Sc2ncccc2[N+](=O)[O-])c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L12 compound treatment 819140.0 -278000.0 -1.36 835000.0 -299000.0 -1.78 646580.0 -342246.5625 -1.96021459289374 -2.9424 -0.9891 2070298 Maybridge1_001486 [O-][N+](=O)c1ccc(Oc2cc(ccc2[N+](=O)[O-])S(=O)(=O)c3ccccc3)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L13 compound treatment 47490.0 -1050000.0 -5.13 48860.0 -1090000.0 -6.45 38760.0 -950066.5625 -5.44149903633551 -9.828 -0.9951 2070299 Maybridge1_001487 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L14 compound treatment 1149530.0 52800.0 0.26 1237650.0 103000.0 0.61 958750.0 -30076.5625 -0.172263283773904 0.4043 0.5873 1076266 Maybridge1_001488 Clc1ccc(NC(=O)c2cccnc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L15 compound treatment 1092550.0 -4190.0 -0.02 1027840.0 -106000.0 -0.63 812570.0 -176256.5625 -1.00950812590203 -0.9602 -0.8057 2070300 Maybridge1_001489 Cc1cc(c(C)cc1Cl)S(=O)(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L16 compound treatment 1021370.0 -75400.0 -0.37 932030.0 -202000.0 -1.2 837340.0 -151486.5625 -0.867638138629396 -1.408 -0.9214 2070301 Maybridge1_001490 Cc1ccc(Sc2ccc(cc2[N+](=O)[O-])C(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L17 compound treatment 951720.0 -145000.0 -0.71 988250.0 -146000.0 -0.87 780820.0 -208006.5625 -1.1913560102745 -1.5983 -0.9771 2070302 Maybridge1_001491 Clc1ccc(SCC2=NNC(=O)C2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L18 compound treatment 1161830.0 65100.0 0.32 1445280.0 311000.0 1.85 1064360.0 75533.4375 0.432617190826941 1.501 0.7795 1046560 Maybridge1_001492 COc1ccc(NC(=S)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L19 compound treatment 1254720.0 158000.0 0.77 1235280.0 101000.0 0.6 990590.0 1763.4375 0.010100074916475 0.7981 0.8161 2070303 Maybridge1_001493 CC(=O)CN1C(=O)c2ccccc2S1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L20 compound treatment 1155910.0 59200.0 0.29 1314350.0 180000.0 1.07 1028080.0 39253.4375 0.224823765786522 0.9149 0.8085 1450792 Maybridge1_001494 COC(=O)c1ccc(Cl)cc1N(Cc2ccccc2)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L21 compound treatment 1101280.0 4540.0 0.02 1257820.0 124000.0 0.73 952680.0 -36146.5625 -0.207029162770468 0.3173 0.4157 1377255 Maybridge1_001495 CCCC(=O)c1cc2cc(Br)ccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L22 compound treatment 1267330.0 171000.0 0.83 1261950.0 128000.0 0.76 954560.0 -34266.5625 -0.196261477018649 0.8061 0.7045 1230653 Maybridge1_001496 Clc1ccc2C(=O)CS(=O)(=O)N(Cc3ccccc3)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L23 mock treatment 1063040.0 -33700.0 -0.16 1117440.0 -16900.0 -0.1 930080.0 -58746.5625 -0.336470491489141 -0.3472 -0.8954 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 L24 mock treatment 1094780.0 -1960.0 -0.01 1130100.0 -4210.0 -0.03 1006820.0 17993.4375 0.10305727691223 0.0395 0.3713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M01 compound treatment 1021830.0 -74900.0 -0.37 1061130.0 -73200.0 -0.44 888430.0 -100396.5625 -0.575020550831298 -0.7945 -0.9825 2070304 Maybridge1_001497 CSC1=NC=C(C#N)C2=NC(NN21)c3ccc(cc3)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M02 compound treatment 978680.0 -118000.0 -0.58 1037540.0 -96800.0 -0.58 983860.0 -4966.5625 -0.0284459490780679 -0.6817 -0.8361 2070305 Maybridge1_001498 CC(=O)C(C)(C)OC(=O)NCCc1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M03 compound treatment 922570.0 -174000.0 -0.85 997120.0 -137000.0 -0.82 822460.0 -166366.5625 -0.952863225856557 -1.5124 -0.9978 2070306 Maybridge1_001499 [O-][N+](=O)c1cccc(Cl)c1Oc2ccc(cc2)c3ccc(Oc4c(Cl)cccc4[N+](=O)[O-])cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M04 compound treatment 923410.0 -173000.0 -0.85 1070950.0 -63400.0 -0.38 833830.0 -154996.5625 -0.887741637027738 -1.219 -0.9498 2070307 Maybridge1_001500 COC(=O)c1cc(OC)c(OC)c(OC)c1NS(=O)(=O)c2cc(OC)ccc2OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M05 compound treatment 982650.0 -114000.0 -0.56 1004480.0 -130000.0 -0.77 861920.0 -126906.5625 -0.726856374916785 -1.1872 -0.991 2070308 Maybridge1_001501 COc1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M06 compound treatment 1184590.0 87900.0 0.43 1080000.0 -54300.0 -0.32 937960.0 -50866.5625 -0.291337851210241 -0.1068 -0.1748 2070309 Maybridge1_001502 COc1ccccc1NC(=O)/C=N/O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M07 compound treatment 981340.0 -115000.0 -0.56 1014080.0 -120000.0 -0.71 837600.0 -151226.5625 -0.866148990599889 -1.2384 -0.9854 2070310 Maybridge1_001503 [O-][N+](=O)c1cc(ccc1Oc2ccc(F)cc2F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M08 compound treatment 845950.0 -251000.0 -1.23 795760.0 -339000.0 -2.01 694480.0 -294346.5625 -1.6858677059192 -2.8431 -0.9812 2070311 Maybridge1_001504 CSC1=NCCN1C(=O)c2nn(nc2C)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M09 compound treatment 1049810.0 -46900.0 -0.23 1102150.0 -32200.0 -0.19 849440.0 -139386.5625 -0.798335480333115 -0.7037 -0.8256 2070312 Maybridge1_001505 [O-][N+](=O)c1cc(ccc1Oc2ccc(cc2)c3ccccc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M10 compound treatment 894410.0 -202000.0 -0.99 869060.0 -265000.0 -1.58 670400.0 -318426.5625 -1.82378572342122 -2.5344 -0.9725 2070313 Maybridge1_001506 CN(C)/C=C(\C#N)/C(=O)Nc1ccc(C)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M11 compound treatment 497010.0 -600000.0 -2.93 513180.0 -621000.0 -3.69 384930.0 -603896.5625 -3.45881298489554 -5.8212 -0.9955 1452789 Maybridge1_001507 Cc1ccc2nc3C(=O)c4ccccc4-c3nc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M12 compound treatment 1092740.0 -4000.0 -0.02 1168910.0 34600.0 0.21 932770.0 -56056.5625 -0.321063536876166 -0.0778 -0.2039 1172166 Maybridge1_001508 Clc1cc(Cl)cc(NC(=O)Cc2nn[nH]n2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M13 compound treatment 1006670.0 -90100.0 -0.44 910460.0 -224000.0 -1.33 770300.0 -218526.5625 -1.25160923054532 -1.7452 -0.9286 2070314 Maybridge1_001509 Nc1ccccc1C(=O)NNc2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M14 compound treatment 1094050.0 -2690.0 -0.01 1078030.0 -56300.0 -0.33 852730.0 -136096.5625 -0.779492030267432 -0.6508 -0.7671 2070315 Maybridge1_001510 COC(=O)CS(=O)(=O)c1cc(C)c(Cl)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M15 compound treatment 1054990.0 -41700.0 -0.2 1027160.0 -107000.0 -0.64 793820.0 -195006.5625 -1.11689860879916 -1.1305 -0.8683 2070316 Maybridge1_001511 Cc1onc(c1C(=O)Nc2ccccc2C(=O)NNc3c(Cl)cc(Cl)cc3Cl)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M16 compound treatment 900540.0 -196000.0 -0.96 915260.0 -219000.0 -1.3 710280.0 -278546.5625 -1.59537332566456 -2.2266 -0.9801 1284149 Maybridge1_001512 O=C(NCC1CC1)c2cccnc2Oc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M17 compound treatment 1169000.0 72300.0 0.35 1066690.0 -67600.0 -0.4 875630.0 -113196.5625 -0.648332453822404 -0.4026 -0.4789 1482069 Maybridge1_001513 COc1cc(C(=O)O)c(NC(=O)C)c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M18 compound treatment 759860.0 -337000.0 -1.65 814120.0 -320000.0 -1.9 608220.0 -380606.5625 -2.17992120217021 -3.3081 -0.9935 1148165 Maybridge1_001514 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)NCC2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M19 compound treatment 846300.0 -250000.0 -1.22 909280.0 -225000.0 -1.34 691390.0 -297436.5625 -1.70356565750065 -2.4626 -0.9898 2070317 Maybridge1_001515 COc1ccc(cc1)/C(=C/c2cc(Br)cs2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M20 compound treatment 1077250.0 -19500.0 -0.1 1302170.0 168000.0 1.0 938240.0 -50586.5625 -0.28973415333231 0.3541 0.3392 2070318 Maybridge1_001516 CN(C)/C=N/S(=O)(=O)c1cc(C)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M21 compound treatment 1012610.0 -84100.0 -0.41 905370.0 -229000.0 -1.36 772800.0 -216026.5625 -1.23729049949237 -1.7377 -0.9218 2070319 Maybridge1_001517 CCCCCC(=O)c1cc(C)c(C)cc1NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M22 compound treatment 1101120.0 4380.0 0.02 1193760.0 59500.0 0.35 985050.0 -3776.5625 -0.0216302330968635 0.204 0.5749 2070320 Maybridge1_001518 Cc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ccc(cn3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M23 mock treatment 1190050.0 93300.0 0.46 1037120.0 -97200.0 -0.58 933050.0 -55776.5625 -0.319459838998236 -0.2549 -0.3176 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 M24 mock treatment 958320.0 -138000.0 -0.68 1115560.0 -18700.0 -0.11 981480.0 -7346.5625 -0.0420773810404769 -0.4791 -0.6977 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N01 compound treatment 984350.0 -112000.0 -0.55 1057920.0 -76400.0 -0.45 944550.0 -44276.5625 -0.253593676154663 -0.7257 -0.9594 2070321 Maybridge1_001519 Fc1cccc(Cl)c1CN(NC(=O)NC(=O)c2c(F)cccc2Cl)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N02 compound treatment 1050910.0 -45800.0 -0.22 990900.0 -143000.0 -0.85 856480.0 -132346.5625 -0.758013933688006 -1.0593 -0.911 2070322 Maybridge1_001520 Oc1cc(ccc1[N+](=O)[O-])S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N03 compound treatment 973690.0 -123000.0 -0.6 1054880.0 -79400.0 -0.47 866440.0 -122386.5625 -0.700968109173051 -1.0245 -0.9877 2070323 Maybridge1_001521 Nc1nnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N04 compound treatment 823940.0 -273000.0 -1.33 837080.0 -297000.0 -1.77 725060.0 -263766.5625 -1.51072098767951 -2.6622 -0.9933 2070324 Maybridge1_001522 Clc1ccc(cc1Cl)C(=O)CN2CCSC2=N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N05 compound treatment 1060670.0 -36100.0 -0.18 1108740.0 -25600.0 -0.15 875570.0 -113256.5625 -0.648676103367675 -0.564 -0.8184 2070325 Maybridge1_001523 N/C(=N\O)/CS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N06 compound treatment 1049340.0 -47400.0 -0.23 1019430.0 -115000.0 -0.68 884180.0 -104646.5625 -0.599362393621313 -0.8741 -0.9321 2070326 Maybridge1_001524 CCc1nn2cc(nc2s1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N07 compound treatment 1125680.0 28900.0 0.14 1068590.0 -65700.0 -0.39 915630.0 -73196.5625 -0.419232756975195 -0.386 -0.6539 2070327 Maybridge1_001525 CC/1=NN(C(=O)\C1=C\c2c(C)nn(c2O)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N08 compound treatment 1017790.0 -78900.0 -0.39 949350.0 -185000.0 -1.1 744440.0 -244386.5625 -1.39972218455704 -1.6658 -0.9146 2070328 Maybridge1_001526 [O-][N+](=O)c1ccc(Sc2ccccc2)cc1OCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N09 compound treatment 979880.0 -117000.0 -0.57 922480.0 -212000.0 -1.26 854400.0 -134426.5625 -0.769927117924061 -1.5014 -0.9485 1037692 Maybridge1_001527 O=C1CC(=NN1c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N10 compound treatment 837400.0 -259000.0 -1.27 815110.0 -319000.0 -1.9 723700.0 -265126.5625 -1.51851037737232 -2.7041 -0.9865 2070329 Maybridge1_001528 CCCc1nn(C)c(O)c1C(=O)c2cc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N11 compound treatment 45730.0 -1050000.0 -5.14 45330.0 -1090000.0 -6.48 34500.0 -954326.5625 -5.46589815404973 -9.8592 -0.995 2070330 Maybridge1_001529 Cc1cc(Sc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N12 compound treatment 1302370.0 206000.0 1.0 1318880.0 185000.0 1.1 942730.0 -46096.5625 -0.264017712361211 1.0613 0.7023 2070331 Maybridge1_001530 CCOC(=O)C(NC(=O)c1nn(nc1C)c2ccccc2)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N13 compound treatment 1033280.0 -63500.0 -0.31 1169810.0 35500.0 0.21 883610.0 -105216.5625 -0.602627064301386 -0.405 -0.5706 2070332 Maybridge1_001531 Clc1ccc(NC(=O)CC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N14 compound treatment 1025040.0 -71700.0 -0.35 1130830.0 -3480.0 -0.02 898080.0 -90746.5625 -0.519750248966908 -0.5143 -0.82 1633510 Maybridge1_001532 Clc1ccc(NC(=O)c2cccnc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N15 compound treatment 832110.0 -265000.0 -1.29 804650.0 -330000.0 -1.96 691260.0 -297566.5625 -1.7043102315154 -2.8622 -0.9864 2070333 Maybridge1_001533 N/C(=N\OS(=O)(=O)c1ccc(Cl)cc1)/c2ccc(cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N16 compound treatment 963150.0 -134000.0 -0.65 944100.0 -190000.0 -1.13 828550.0 -160276.5625 -0.91798279701157 -1.5599 -0.9772 2070334 Maybridge1_001534 Cc1cc(Sc2ccc(cc2[N+](=O)[O-])C(=O)O)c(C)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N17 compound treatment 1027250.0 -69500.0 -0.34 1215760.0 81500.0 0.48 1002370.0 13543.4375 0.0775699356379781 0.1284 0.2153 2070335 Maybridge1_001535 CN(C)/C=C\1/C(=O)NN=C1CSc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N18 compound treatment 1207710.0 111000.0 0.54 1223160.0 88900.0 0.53 1001630.0 12803.4375 0.0733315912463048 0.6604 0.8683 2070336 Maybridge1_001536 Clc1ccc(cc1)c2nnnn2c3cnccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N19 compound treatment 1142560.0 45800.0 0.22 1415260.0 281000.0 1.67 1057150.0 68323.4375 0.391321970470231 1.3198 0.7627 2070337 Maybridge1_001537 CN(C)/C=C\1/C(=O)NN=C1CSc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N20 compound treatment 1290050.0 193000.0 0.94 1393960.0 260000.0 1.54 945630.0 -43196.5625 -0.247407984339788 1.2939 0.7083 2070338 Maybridge1_001538 COc1ccc(Br)c(c1)C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N21 compound treatment 1014750.0 -82000.0 -0.4 1062240.0 -72100.0 -0.43 773760.0 -215066.5625 -1.23179210676803 -1.1899 -0.8721 2070339 Maybridge1_001539 CCCC(=O)c1cc2ccccc2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N22 compound treatment 1201090.0 104000.0 0.51 1278830.0 145000.0 0.86 1015520.0 26693.4375 0.152886460976498 0.8788 0.8693 2070340 Maybridge1_001540 [O-][N+](=O)c1ccccc1C(=O)NNC(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N23 mock treatment 1099680.0 2940.0 0.01 1187370.0 53100.0 0.32 1087290.0 98463.4375 0.563948592044603 0.5161 0.7984 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 N24 mock treatment 1022760.0 -74000.0 -0.36 1183470.0 49200.0 0.29 1026780.0 37953.4375 0.217378025638988 0.0856 0.1668 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O01 compound treatment 874080.0 -223000.0 -1.09 978410.0 -156000.0 -0.93 825830.0 -162996.5625 -0.93356157639718 -1.7023 -0.9972 2070341 Maybridge1_001541 CS/C(=N/N=C/c1c(F)cccc1Cl)/N=C/N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O02 compound treatment 1122560.0 25800.0 0.13 1138240.0 3930.0 0.02 917560.0 -71266.5625 -0.408178696602317 -0.1493 -0.349 2070342 Maybridge1_001542 COc1ccc(CCNC(=O)OC(C)(C)C(=O)C)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O03 compound treatment 646400.0 -450000.0 -2.2 746630.0 -388000.0 -2.31 632020.0 -356806.5625 -2.04360688254612 -3.7812 -0.9988 2070343 Maybridge1_001543 Cc1ccc(N(CC=C)C2=NC(C)(C)C(=C)S2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O04 compound treatment 1012420.0 -84300.0 -0.41 1030900.0 -103000.0 -0.61 863960.0 -124866.5625 -0.715172290377578 -1.0058 -0.9772 2070344 Maybridge1_001544 CC(C)(C)SCCNc1nc(Oc2ccc(Cl)cc2)nc(Oc3ccc(Cl)cc3)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O05 compound treatment 719200.0 -378000.0 -1.84 684000.0 -450000.0 -2.68 574660.0 -414166.5625 -2.37213584782502 -3.9805 -0.989 2070345 Maybridge1_001545 COC(=O)c1sc2ccccc2c1OS(=O)(=O)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O06 compound treatment 1077540.0 -19200.0 -0.09 1047580.0 -86700.0 -0.52 848280.0 -140546.5625 -0.804979371541684 -0.8167 -0.8502 2070346 Maybridge1_001546 OCCCCCNc1ccc(cn1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O07 compound treatment 1107210.0 10500.0 0.05 1213200.0 78900.0 0.47 967410.0 -21416.5625 -0.122663199406483 0.2296 0.4708 2070347 Maybridge1_001547 CSc1ncc(C#N)c2nc(nn12)c3ccc(cc3)N(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O08 compound treatment 976320.0 -120000.0 -0.59 969290.0 -165000.0 -0.98 743330.0 -245496.5625 -1.40607970114455 -1.718 -0.9477 2070348 Maybridge1_001548 CSC1=NCCCN1C(=O)c2nn(nc2C)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O09 compound treatment 1159800.0 63100.0 0.31 1104530.0 -29800.0 -0.18 904670.0 -84156.5625 -0.482006073911331 -0.2026 -0.3384 1555636 Maybridge1_001549 Clc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4ncccc4c(=O)c3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O10 compound treatment 973250.0 -123000.0 -0.6 923610.0 -211000.0 -1.25 813250.0 -175576.5625 -1.00561343105563 -1.6523 -0.9628 2070349 Maybridge1_001550 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)n(n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O11 compound treatment 1066690.0 -30000.0 -0.15 995400.0 -139000.0 -0.83 833940.0 -154886.5625 -0.887111612861408 -1.0738 -0.8795 2070350 Maybridge1_001551 CCOC(=O)/C(=C/Nc1ccc2oc3ncccc3c(=O)c2c1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O12 compound treatment 779280.0 -317000.0 -1.55 940320.0 -194000.0 -1.15 794170.0 -194656.5625 -1.11489398645175 -2.2052 -0.9882 2070351 Maybridge1_001552 COC(=O)CSc1cc(C)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O13 compound treatment 333300.0 -763000.0 -3.73 308770.0 -826000.0 -4.91 194020.0 -794806.5625 -4.55224856302306 -7.616 -0.9938 2070352 Maybridge1_001553 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(F)cc2F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O14 compound treatment 755760.0 -341000.0 -1.67 810320.0 -324000.0 -1.93 620750.0 -368076.5625 -2.10815572213282 -3.2913 -0.9955 2070353 Maybridge1_001554 [O-][N+](=O)c1cc(ccc1SCC(=O)Nc2ccc(F)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O15 compound treatment 1047210.0 -49500.0 -0.24 1155250.0 20900.0 0.12 890570.0 -98256.5625 -0.562763717049972 -0.3927 -0.6282 1047215 Maybridge1_001555 COc1cc(C(=O)O)c(N)c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O16 compound treatment 1032130.0 -64600.0 -0.32 1188640.0 54300.0 0.32 1012160.0 23333.4375 0.133642086441333 0.0815 0.1729 1739779 Maybridge1_001556 Fc1ccccc1C(=O)NC(=O)NCC2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O17 compound treatment 999470.0 -97300.0 -0.48 1130830.0 -3480.0 -0.02 886890.0 -101936.5625 -0.583840889159915 -0.6234 -0.8278 2070354 Maybridge1_001557 [O-][N+](=O)c1ccc(o1)c2nc3ccccc3c(=O)o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O18 compound treatment 1072530.0 -24200.0 -0.12 1222650.0 88300.0 0.53 966120.0 -22706.5625 -0.130051664629805 0.1599 0.2887 1274234 Maybridge1_001558 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O19 compound treatment 1189400.0 92700.0 0.45 1299250.0 165000.0 0.98 958040.0 -30786.5625 -0.176329803392942 0.7259 0.6632 2070355 Maybridge1_001559 Fc1ccc(NC(=O)/C(=C/c2cc(Br)cs2)/C#N)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O20 compound treatment 1087290.0 -9450.0 -0.05 1172050.0 37700.0 0.22 922650.0 -66176.5625 -0.37902576017851 -0.1159 -0.2617 1128554 Maybridge1_001560 Cc1nn(nc1C(=O)NC(=O)N2CCCC2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O21 compound treatment 809920.0 -287000.0 -1.4 924730.0 -210000.0 -1.25 815780.0 -173046.5625 -0.991122875230041 -2.1008 -0.9904 2070356 Maybridge1_001561 Fc1ccc(cc1Cl)S(=O)(=O)NC(=N)CSc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O22 compound treatment 1180880.0 84100.0 0.41 1292050.0 158000.0 0.94 968510.0 -20316.5625 -0.116362957743185 0.7117 0.6905 2070357 Maybridge1_001562 COC(=O)c1sccc1OC(=O)c2cccnc2Oc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O23 mock treatment 1148320.0 51600.0 0.25 1235310.0 101000.0 0.6 1049080.0 60253.4375 0.345101106631307 0.6915 0.9381 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 O24 mock treatment 973890.0 -123000.0 -0.6 1070820.0 -63500.0 -0.38 968870.0 -19956.5625 -0.11430106047156 -0.6305 -0.8778 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P01 compound treatment 900280.0 -196000.0 -0.96 899840.0 -234000.0 -1.39 939600.0 -49226.5625 -0.281944763639505 -1.5219 -0.8869 2070358 Maybridge1_001563 Fc1cccc(Cl)c1CN(NC(=O)C(Cl)(Cl)Cl)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P02 compound treatment 1093620.0 -3120.0 -0.02 1193870.0 59600.0 0.35 1028000.0 39173.4375 0.224365566392828 0.3252 0.7752 1489801 Maybridge1_001564 CSc1ncccc1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P03 compound treatment 958450.0 -138000.0 -0.68 956380.0 -178000.0 -1.06 819160.0 -169666.5625 -0.971763950846452 -1.562 -0.9839 2070359 Maybridge1_001565 Nc1nnc(Sc2nc3c(Cl)cc(Cl)cc3s2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P04 compound treatment 953320.0 -143000.0 -0.7 1147450.0 13100.0 0.08 946290.0 -42536.5625 -0.243627839341809 -0.5001 -0.6704 2070360 Maybridge1_001566 Cc1cc(c(C)cc1Cl)S(=O)(=O)Oc2ccc(OCc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P05 compound treatment 1112580.0 15800.0 0.08 1252930.0 119000.0 0.71 1056710.0 67883.4375 0.388801873804912 0.6764 0.836 1602461 Maybridge1_001567 Cc1ccc2nc3sc4ccc(Cl)cc4n3c(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P06 compound treatment 1038600.0 -58100.0 -0.28 1093620.0 -40700.0 -0.24 930020.0 -58806.5625 -0.336814141034412 -0.4981 -0.991 2070361 Maybridge1_001568 CC(C)(C)c1cn2nc(sc2n1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P07 compound treatment 978410.0 -118000.0 -0.58 1133600.0 -708.0 0.0 913650.0 -75176.5625 -0.430573191969132 -0.5848 -0.8113 2070362 Maybridge1_001569 CN(C)/C=C/1\C(=NN(C)C1=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P08 compound treatment 817080.0 -280000.0 -1.37 909120.0 -225000.0 -1.34 758910.0 -229916.5625 -1.31684536922256 -2.3223 -0.9999 2070363 Maybridge1_001570 Cc1nn(nc1C(=O)NNC(=O)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P09 compound treatment 992490.0 -104000.0 -0.51 1019010.0 -115000.0 -0.69 886480.0 -102346.5625 -0.586189161052599 -1.0283 -0.9927 2070364 Maybridge1_001571 Cc1n[nH]c2oc(=O)c([N+](=O)[O-])c(C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P10 compound treatment 973650.0 -123000.0 -0.6 1021810.0 -112000.0 -0.67 860050.0 -128776.5625 -0.737566785744392 -1.1593 -0.9966 2070365 Maybridge1_001572 Clc1cccc(NC(=O)CC#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P11 compound treatment 1080830.0 -15900.0 -0.08 1135220.0 912.0 0.01 924640.0 -64186.5625 -0.367628050260361 -0.254 -0.6759 2070366 Maybridge1_001573 Cc1cc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c(Cl)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P12 compound treatment 1117770.0 21000.0 0.1 1162430.0 28100.0 0.17 934640.0 -54186.5625 -0.310353126048559 -0.0233 -0.0634 2070367 Maybridge1_001574 CCOC(=O)C(NC(=O)c1cc2ccccc2s1)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P13 compound treatment 1184070.0 87300.0 0.43 1045440.0 -88900.0 -0.53 967630.0 -21196.5625 -0.121403151073823 -0.1288 -0.1867 1008534 Maybridge1_001575 O=C(CC#N)Nc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P14 compound treatment 1073340.0 -23400.0 -0.11 1093380.0 -40900.0 -0.24 980580.0 -8246.5625 -0.0472321242195391 -0.2338 -0.8563 1518071 Maybridge1_001576 CCCC1=NN(C(=O)C1)c2ccc(cc2)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P15 compound treatment 815380.0 -281000.0 -1.37 800530.0 -334000.0 -1.98 766590.0 -222236.5625 -1.2728582274279 -2.6745 -0.9799 2070368 Maybridge1_001577 Cc1ccc(cc1)S(=O)(=O)O/N=C(\N)/c2ccc(cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P16 compound treatment 1072750.0 -24000.0 -0.12 1227250.0 92900.0 0.55 1088590.0 99763.4375 0.571394332192138 0.5813 0.7235 2070369 Maybridge1_001578 Cc1ccc(cc1)S(=O)(=O)c2ccc(cc2[N+](=O)[O-])C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P17 compound treatment 1133150.0 36400.0 0.18 1263220.0 129000.0 0.77 1052960.0 64133.4375 0.367323777225486 0.7574 0.8721 1484466 Maybridge1_001579 CCCSc1ncccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P18 compound treatment 1088900.0 -7840.0 -0.04 1177040.0 42700.0 0.25 996600.0 7773.4375 0.0445223043677682 0.1503 0.5763 2070370 Maybridge1_001580 Cc1cc(=O)oc2n(nc(c12)C(F)(F)F)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P19 compound treatment 1127370.0 30600.0 0.15 1177770.0 43500.0 0.26 975060.0 -13766.5625 -0.078847882384454 0.1901 0.6154 2070371 Maybridge1_001581 CN(C)/C=C\1/C(=O)NN=C1CSc2cc(C)c(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P20 compound treatment 908700.0 -188000.0 -0.92 909600.0 -225000.0 -1.34 798520.0 -190306.5625 -1.08997939441961 -1.9312 -0.9884 2070372 Maybridge1_001582 CC(C)(C)c1ccc(cc1)C(=O)NNC(=O)c2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P21 compound treatment 1151300.0 54600.0 0.27 1200640.0 66300.0 0.39 1084580.0 95753.4375 0.548427087583205 0.6983 0.9615 1740892 Maybridge1_001583 CCCc1cc(=O)oc2n(nc(C)c12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P22 compound treatment 778090.0 -319000.0 -1.56 917060.0 -217000.0 -1.29 757650.0 -231176.5625 -1.32406200967325 -2.4092 -0.9964 2070373 Maybridge1_001584 CC(C)(C)c1ccc(cc1)C(=O)NNC(=O)c2ccccc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P23 mock treatment 1051590.0 -45100.0 -0.22 1125790.0 -8520.0 -0.05 1063280.0 74453.4375 0.426431499012066 0.0896 0.1856 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.545 P24 mock treatment 956410.0 -140000.0 -0.69 898350.0 -236000.0 -1.4 988830.0 3.4375 1.9688255197807E-5 -1.2059 -0.7722 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A01 compound treatment 954660.0 -60300.0 -0.29 878200.0 -71300.0 -0.42 832720.0 -117465.806451613 -0.672784516199437 -0.8032 -0.9472 2070374 Maybridge1_001585 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A02 compound treatment 1037240.0 22300.0 0.11 949510.0 31.6 0.0 900130.0 -50055.806451613 -0.286694252087678 -0.1026 -0.3344 2070375 Maybridge1_001586 Cc1ccc(OS(=O)(=O)c2ccc(Cl)cc2)c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A03 compound treatment 1010330.0 -4630.0 -0.02 956550.0 7070.0 0.04 958590.0 8404.19354838703 0.0481349548545185 0.039 0.5755 2070376 Maybridge1_001587 Nc1ccccc1c2nnc(o2)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A04 compound treatment 1079090.0 64100.0 0.31 941560.0 -7920.0 -0.05 978160.0 27974.193548387 0.160221981537016 0.2462 0.6935 2070377 Maybridge1_001588 CC(=O)Nc1ccc(cc1Br)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A05 compound treatment 1069820.0 54900.0 0.27 997480.0 48000.0 0.29 942440.0 -7745.80645161297 -0.0443640477475422 0.2939 0.7459 2070378 Maybridge1_001589 FC(F)(F)C1=NNC(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A06 compound treatment 1066880.0 51900.0 0.25 1007610.0 58100.0 0.35 1061710.0 111524.193548387 0.638753973326624 0.7148 0.9292 2070379 Maybridge1_001590 CC(C)(C)c1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A07 compound treatment 873360.0 -142000.0 -0.69 894660.0 -54800.0 -0.33 881230.0 -68955.806451613 -0.394943858847984 -0.8156 -0.9476 1036891 Maybridge1_001591 CC(C)(C)C1=NN(C(=O)C1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A08 compound treatment 1044520.0 29600.0 0.14 979940.0 30500.0 0.18 1000480.0 50294.193548387 0.288059612377758 0.3543 0.9584 2070380 Maybridge1_001592 COc1ccc(Br)cc1S(=O)(=O)Oc2c(Cl)cc(cc2Br)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A09 compound treatment 1038170.0 23200.0 0.11 1023170.0 73700.0 0.44 935260.0 -14925.806451613 -0.0854874433316163 0.2691 0.5842 2070381 Maybridge1_001593 Clc1ccc(cc1)S(=O)(=O)Oc2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A10 compound treatment 1034930.0 20000.0 0.1 925400.0 -24100.0 -0.14 932680.0 -17505.806451613 -0.100264373778261 -0.0842 -0.4207 2070382 Maybridge1_001594 NC(=O)c1sc2ccccc2c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A11 compound treatment 988270.0 -26700.0 -0.13 944320.0 -5160.0 -0.03 833450.0 -116735.806451613 -0.668603446731976 -0.479 -0.7025 2070383 Maybridge1_001595 C/C(=N\OC(=O)c1ccc(Cl)cc1)/c2ccn(c2)S(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A12 compound treatment 1093840.0 78900.0 0.39 964200.0 14700.0 0.09 882990.0 -67195.806451613 -0.384863472186707 0.0509 0.0922 1169386 Maybridge1_001596 COc1ccc(Br)c(OC)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A13 compound treatment 1024000.0 9040.0 0.04 914080.0 -35400.0 -0.21 877460.0 -72725.806451613 -0.416536505275834 -0.3365 -0.7178 2070384 Maybridge1_001597 [O-][N+](=O)c1ccc(Sc2cc(Cl)ccc2Cl)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A14 compound treatment 958040.0 -56900.0 -0.28 876160.0 -73300.0 -0.44 990630.0 40444.193548387 0.231643812029133 -0.2785 -0.4916 2070385 Maybridge1_001598 COc1c(Cl)cc([N+](=O)[O-])c(OC)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A15 compound treatment 924240.0 -90700.0 -0.44 830040.0 -119000.0 -0.71 837210.0 -112975.806451613 -0.647068075228338 -1.0395 -0.9825 2070386 Maybridge1_001599 C/C(=N\OC(=O)c1cc2ccccc2s1)/c3cc[nH]c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A16 compound treatment 775440.0 -240000.0 -1.17 690880.0 -259000.0 -1.54 722360.0 -227825.806451613 -1.30487057980089 -2.3168 -0.9936 2070387 Maybridge1_001600 [O-][N+](=O)c1ccc2ncccc2c1n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A17 compound treatment 809320.0 -206000.0 -1.0 727850.0 -222000.0 -1.32 712410.0 -237775.806451613 -1.36185912939163 -2.1272 -0.9917 1262589 Maybridge1_001601 Cc1cc(Oc2ccc(N)cn2)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A18 compound treatment 904290.0 -111000.0 -0.54 856880.0 -92600.0 -0.55 749360.0 -200825.806451613 -1.15022828442902 -1.2942 -0.9343 2070388 Maybridge1_001602 Clc1ccc(cc1)C(=O)CSC(=S)NNc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A19 compound treatment 982330.0 -32600.0 -0.16 901760.0 -47700.0 -0.28 896160.0 -54025.806451613 -0.309432396999763 -0.4345 -0.9676 2070389 Maybridge1_001603 C/C(=N\N=C(/N)\SCc1ccc(Cl)cc1Cl)/c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A20 compound treatment 972000.0 -43000.0 -0.21 897690.0 -51800.0 -0.31 877380.0 -72805.806451613 -0.416994704669528 -0.5397 -0.9651 2070390 Maybridge1_001604 CCOC(=O)N1CCCN=C1SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A21 compound treatment 961920.0 -53000.0 -0.26 919410.0 -30100.0 -0.18 835150.0 -115035.806451613 -0.658866709615969 -0.6332 -0.8672 2070391 Maybridge1_001605 Cc1ccc(OCc2ccc(Cl)c(Cl)c2)c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A22 compound treatment 1009460.0 -5500.0 -0.03 944550.0 -4930.0 -0.03 895200.0 -54985.806451613 -0.314930789724096 -0.2143 -0.675 2070392 Maybridge1_001606 CN(C)/C=N/c1n[nH]c(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A23 mock treatment 966080.0 -48900.0 -0.24 871540.0 -77900.0 -0.46 886810.0 -63375.806451613 -0.362984451137799 -0.615 -0.9681 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 A24 mock treatment 974080.0 -40900.0 -0.2 878100.0 -71400.0 -0.42 852800.0 -97385.806451613 -0.557776468382138 -0.6824 -0.9363 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B01 compound treatment 625280.0 -390000.0 -1.9 606150.0 -343000.0 -2.04 462790.0 -487395.806451613 -2.79155578756664 -3.8897 -0.9852 2070393 Maybridge1_001607 CN(C)Cc1ccc(CSCCNC(=O)Nc2ccc(Cl)cc2)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B02 compound treatment 988800.0 -26200.0 -0.13 864690.0 -84800.0 -0.5 885510.0 -64675.806451613 -0.370430191285333 -0.5788 -0.9063 2070394 Maybridge1_001608 O=C(NNc1ccccc1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B03 compound treatment 1111800.0 96800.0 0.47 1012160.0 62700.0 0.37 999930.0 49744.193548387 0.284909491546109 0.6529 0.9798 1389651 Maybridge1_001609 O=S(=O)(NCc1cccnc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B04 compound treatment 961650.0 -53300.0 -0.26 904960.0 -44500.0 -0.26 1007040.0 56854.193548387 0.325631962660701 -0.1152 -0.2333 1135267 Maybridge1_001610 COc1ccc(OC)c(CNC(=O)Cc2cccs2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B05 compound treatment 936930.0 -78000.0 -0.38 874420.0 -75100.0 -0.45 791160.0 -159025.806451613 -0.910819101223688 -1.0037 -0.9262 2070395 Maybridge1_001611 COc1ccc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B06 compound treatment 1020710.0 5750.0 0.03 931770.0 -17700.0 -0.11 904240.0 -45945.806451613 -0.263154258236627 -0.1965 -0.6899 1245092 Maybridge1_001612 COC(=O)CNC(=O)c1cccnc1Oc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B07 compound treatment 987620.0 -27300.0 -0.13 1062450.0 113000.0 0.67 921660.0 -28525.806451613 -0.163381340259667 0.2164 0.3073 1583698 Maybridge1_001613 COc1ccccc1N2CC(C)(C)C(=O)NC2=S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B08 compound treatment 1007310.0 -7650.0 -0.04 921520.0 -28000.0 -0.17 851360.0 -98825.806451613 -0.566024057468638 -0.4444 -0.7517 2070396 Maybridge1_001614 CCOC(=O)CNC(=O)c1cccnc1Oc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B09 compound treatment 1073760.0 58800.0 0.29 994560.0 45100.0 0.27 936440.0 -13745.806451613 -0.0787290022746236 0.2752 0.6867 2070397 Maybridge1_001615 CCOC(=O)N1CCCN=C1NNc2cc(Cl)ccc2OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B10 compound treatment 955210.0 -59700.0 -0.29 846880.0 -103000.0 -0.61 915520.0 -34665.806451613 -0.198548143725714 -0.6354 -0.9014 2070398 Maybridge1_001616 CCOC(=O)CNC(=O)c1cc(ccc1Oc2ccc(OC)cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B11 compound treatment 920570.0 -94400.0 -0.46 878560.0 -70900.0 -0.42 786000.0 -164185.806451613 -0.940372962116978 -1.0527 -0.9323 2070399 Maybridge1_001617 Cc1cc(cc(C)c1OC(=O)Nc2ccc(OC(F)(F)F)cc2)c3nn(C)c(=O)c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B12 compound treatment 649360.0 -366000.0 -1.79 610440.0 -339000.0 -2.02 644980.0 -305205.806451613 -1.74806394335181 -3.2045 -0.998 2070400 Maybridge1_001618 CCOC(=O)c1nn(c2ccc(Cl)cc2)c(=N)c(C#N)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B13 compound treatment 727330.0 -288000.0 -1.41 747360.0 -202000.0 -1.2 531740.0 -418445.806451613 -2.39664518512626 -2.889 -0.9544 2070401 Maybridge1_001619 COc1ccc(Oc2ccc(NC(=O)Nc3ccc(SC(F)(F)F)cc3)cn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B14 compound treatment 819740.0 -195000.0 -0.95 807060.0 -142000.0 -0.85 786880.0 -163305.806451613 -0.935332768786339 -1.5796 -0.9987 2070402 Maybridge1_001620 Clc1cccc(c1)C(=O)OCCSc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B15 compound treatment 846970.0 -168000.0 -0.82 814660.0 -135000.0 -0.8 753660.0 -196525.806451613 -1.12560006701795 -1.5866 -0.9871 2070403 Maybridge1_001621 Cc1ccc(SCC(=O)Nc2ccc(F)c(F)c2F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B16 compound treatment 688200.0 -327000.0 -1.6 612240.0 -337000.0 -2.01 573680.0 -376505.806451613 -2.15643415298196 -3.3246 -0.9925 2070404 Maybridge1_001622 Cc1n[nH]c(=O)c2noc(/C=C/c3ccsc3)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B17 compound treatment 895480.0 -119000.0 -0.58 858720.0 -90800.0 -0.54 883680.0 -66505.806451613 -0.380911502416093 -0.8685 -0.9852 2070405 Maybridge1_001623 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B18 compound treatment 995010.0 -19900.0 -0.1 974560.0 25100.0 0.15 960680.0 10494.193548387 0.0601054140147852 0.0645 0.3433 2070406 Maybridge1_001624 COc1cc(OC)c([N+](=O)[O-])c(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B19 compound treatment 1106560.0 91600.0 0.45 906400.0 -43100.0 -0.26 981700.0 31514.193548387 0.180497304707994 0.2147 0.393 2070407 Maybridge1_001625 COC(=O)c1ccc(Cl)cc1N(CCCC#N)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B20 compound treatment 1017160.0 2200.0 0.01 958520.0 9040.0 0.05 925310.0 -24875.806451613 -0.14247599292236 -0.045 -0.2948 1008366 Maybridge1_001626 [O-][N+](=O)c1ccc(NN=C2CCCCC2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B21 compound treatment 1022830.0 7870.0 0.04 873490.0 -76000.0 -0.45 948680.0 -1505.80645161297 -0.00862449503937757 -0.2437 -0.5372 2070408 Maybridge1_001627 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2NS(=O)(=O)c3ccc(C)cc3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B22 compound treatment 996750.0 -18200.0 -0.09 986820.0 37300.0 0.22 927130.0 -23055.806451613 -0.132051956715812 6.0E-4 0.0022 2070409 Maybridge1_001628 Cn1nc(O)cc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B23 mock treatment 1025640.0 10700.0 0.05 1012970.0 63500.0 0.38 922920.0 -27265.806451613 -0.15616469980898 0.158 0.3835 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 B24 mock treatment 1045170.0 30200.0 0.15 924120.0 -25400.0 -0.15 926890.0 -23295.806451613 -0.133426554896895 -0.0789 -0.3159 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C01 compound treatment 1051390.0 36400.0 0.18 915240.0 -34200.0 -0.2 960410.0 10224.193548387 0.0585589910610666 0.019 0.0688 2070410 Maybridge1_001629 [O-][N+](=O)c1ccccc1c2nnc(o2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C02 compound treatment 975970.0 -39000.0 -0.19 905790.0 -43700.0 -0.26 846810.0 -103375.806451613 -0.592084147985008 -0.6018 -0.8928 1438164 Maybridge1_001630 COc1ccc(COc2ccc(CC#N)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C03 compound treatment 1081570.0 66600.0 0.33 834130.0 -115000.0 -0.69 975090.0 24904.193548387 0.142638579803992 -0.1258 -0.1628 1286595 Maybridge1_001631 OC(=O)CCC(=O)Nc1ccccc1c2nnc(o2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C04 compound treatment 1167200.0 152000.0 0.74 1020590.0 71100.0 0.42 1057530.0 107344.193548387 0.614813055006091 1.0286 0.9762 2070411 Maybridge1_001632 Clc1cncc(OS(=O)(=O)c2cc(Cl)cc(Cl)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C05 compound treatment 1025980.0 11000.0 0.05 899720.0 -49800.0 -0.3 879570.0 -70615.806451613 -0.404451496267143 -0.3733 -0.7406 2070412 Maybridge1_001633 Fc1ccc(cc1F)c2cn(c3ccccc3)c(=Nc4ccccc4)s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C06 compound treatment 832480.0 -182000.0 -0.89 785540.0 -164000.0 -0.97 782000.0 -168185.806451613 -0.963282931801699 -1.6337 -0.9992 2070413 Maybridge1_001634 CC(C)(C)c1ccc(Oc2ccc(cn2)[N+](=O)[O-])c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C07 compound treatment 1065510.0 50600.0 0.25 1013600.0 64100.0 0.38 1014480.0 64294.193548387 0.368244506274282 0.5754 0.9838 1503866 Maybridge1_001635 Cc1onc(c1C(=O)Oc2ccc(CC#N)cc2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C08 compound treatment 1185410.0 170000.0 0.83 964800.0 15300.0 0.09 975240.0 25054.193548387 0.143497703667169 0.6163 0.725 2070414 Maybridge1_001636 CC(C)(C)c1cc(Cl)c(OS(=O)(=O)c2cc(Cl)cc(Cl)c2)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C09 compound treatment 1041880.0 26900.0 0.13 918050.0 -31400.0 -0.19 1060670.0 110484.193548387 0.632797381208597 0.3334 0.4955 2070415 Maybridge1_001637 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C10 compound treatment 953390.0 -61600.0 -0.3 887140.0 -62300.0 -0.37 856830.0 -93355.806451613 -0.534694673924782 -0.6964 -0.9715 2070416 Maybridge1_001638 [O-][N+](=O)c1cccnc1NCc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C11 compound treatment 1112580.0 97600.0 0.48 1006280.0 56800.0 0.34 871400.0 -78785.806451613 -0.451245109348186 0.2099 0.2842 2070417 Maybridge1_001639 C/C(=N\OC(=O)c1ccc(cc1)C(F)(F)F)/c2ccn(c2)S(=O)(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C12 compound treatment 945600.0 -69400.0 -0.34 844340.0 -105000.0 -0.63 946510.0 -3675.80645161297 -0.0210531535933387 -0.5688 -0.7994 1478654 Maybridge1_001640 COc1ccc(Br)c(OC)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C13 compound treatment 1139680.0 125000.0 0.61 1098590.0 149000.0 0.89 963550.0 13364.193548387 0.0765433172635725 0.908 0.8418 2070418 Maybridge1_001641 CC(=O)c1cccn1S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C14 compound treatment 963450.0 -51500.0 -0.25 876320.0 -73200.0 -0.44 888860.0 -61325.806451613 -0.351243091674379 -0.5993 -0.9773 2070419 Maybridge1_001642 Nc1nnc(SCC#N)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C15 compound treatment 998080.0 -16900.0 -0.08 933730.0 -15700.0 -0.09 976290.0 26104.193548387 0.149511570709409 -0.0154 -0.0789 1565189 Maybridge1_001643 CC(C)Oc1ccccc1Oc2ccc(N)cn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C16 compound treatment 984320.0 -30600.0 -0.15 867430.0 -82000.0 -0.49 885680.0 -64505.806451613 -0.369456517573732 -0.5814 -0.9228 2070420 Maybridge1_001644 CCOC(=O)CC(=O)CSc1nnc(NC(=O)c2c(F)cccc2F)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C17 compound treatment 672570.0 -342000.0 -1.67 696250.0 -253000.0 -1.51 594630.0 -355555.806451613 -2.03644318675824 -3.011 -0.992 1225421 Maybridge1_001645 CC(C)c1cc(Oc2ccc(N)cn2)cc(c1)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C18 compound treatment 956210.0 -58700.0 -0.29 1152480.0 203000.0 1.21 926430.0 -23755.806451613 -0.136061201410638 0.4527 0.3627 2070421 Maybridge1_001646 [O-][N+](=O)c1cccc(c1)c2csc(=S)n2N(C(=O)c3ccc(cc3)C(F)(F)F)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C19 compound treatment 963410.0 -51500.0 -0.25 929150.0 -20300.0 -0.12 935310.0 -14875.806451613 -0.0852010687105573 -0.2644 -0.9052 2070422 Maybridge1_001647 CCO/N=C(\C)/c1ccc(C)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C20 compound treatment 972200.0 -42800.0 -0.21 810480.0 -139000.0 -0.83 936820.0 -13365.806451613 -0.0765525551545751 -0.642 -0.75 2070423 Maybridge1_001648 Cn1cc(C(=O)Nc2ccc(F)c(F)c2F)c(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C21 compound treatment 938310.0 -76600.0 -0.37 860740.0 -88700.0 -0.53 877890.0 -72295.806451613 -0.414073683534726 -0.7599 -0.9892 1781058 Maybridge1_001649 Cc1cccc(NC(=O)c2ccc(Cl)cc2[N+](=O)[O-])n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C22 compound treatment 879260.0 -136000.0 -0.66 793330.0 -156000.0 -0.93 866610.0 -83575.806451613 -0.478679798045639 -1.1952 -0.966 2070424 Maybridge1_001650 [O-][N+](=O)c1cccnc1Oc2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C23 mock treatment 1013600.0 -1360.0 -0.01 887890.0 -61600.0 -0.37 918200.0 -31985.806451613 -0.183198464036951 -0.321 -0.7839 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 C24 mock treatment 941370.0 -73600.0 -0.36 867360.0 -82100.0 -0.49 882460.0 -67725.806451613 -0.387899043169933 -0.7135 -0.9911 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D01 compound treatment 1077380.0 62400.0 0.3 896410.0 -53100.0 -0.32 957220.0 7034.19354838703 0.0402882902375016 0.0171 0.0389 2070425 Maybridge1_001651 Nc1cccnc1Oc2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D02 compound treatment 1138430.0 123000.0 0.6 1020760.0 71300.0 0.42 1032100.0 81914.193548387 0.469162922735477 0.8639 0.9885 1679983 Maybridge1_001652 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(C)cc2NS(=O)(=O)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D03 compound treatment 801700.0 -213000.0 -1.04 906410.0 -43100.0 -0.26 736410.0 -213775.806451613 -1.22439931128331 -1.4563 -0.8946 1304103 Maybridge1_001653 Clc1ccc(CNS(=O)(=O)c2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D04 compound treatment 1173280.0 158000.0 0.77 983640.0 34200.0 0.2 913820.0 -36365.806451613 -0.20828488084172 0.4436 0.5368 2070426 Maybridge1_001654 CN(C)/C=N/c1cc(C)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D05 compound treatment 751140.0 -264000.0 -1.29 727850.0 -222000.0 -1.32 665120.0 -285065.806451613 -1.63271224598924 -2.4477 -0.994 2070427 Maybridge1_001655 [O-][N+](=O)c1ccc(Sc2ccccc2)c(C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D06 compound treatment 1070150.0 55200.0 0.27 958580.0 9100.0 0.05 946270.0 -3915.80645161297 -0.0224277517744219 0.174 0.6305 1575755 Maybridge1_001656 COc1ccc(SCC(=O)O)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D07 compound treatment 1010440.0 -4520.0 -0.02 1008740.0 59300.0 0.35 883160.0 -67025.806451613 -0.383889798475106 -0.0309 -0.0593 1662175 Maybridge1_001657 COc1ccc(cc1)n2c(=S)[nH]c(=O)c3cccnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D08 compound treatment 1005360.0 -9600.0 -0.05 930690.0 -18800.0 -0.11 931930.0 -18255.806451613 -0.104559993094146 -0.1519 -0.9494 1709190 Maybridge1_001658 Cc1ccc(cc1)S(=O)(=O)N(CC=C)c2ccccc2C(=O)NCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D09 compound treatment 1061090.0 46100.0 0.23 1008960.0 59500.0 0.35 886620.0 -63565.806451613 -0.364072674697823 0.1241 0.2235 2070428 Maybridge1_001659 COc1ccccc1N2CC(C)(C)C(=O)N=C2Sc3ccc(cc3[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D10 compound treatment 974560.0 -40400.0 -0.2 931690.0 -17800.0 -0.11 842880.0 -107305.806451613 -0.614593193200246 -0.5299 -0.81 2070429 Maybridge1_001660 COc1ccc(Oc2ccc(cc2C(=O)NCC(=O)O)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D11 compound treatment 816860.0 -198000.0 -0.97 739590.0 -210000.0 -1.25 747200.0 -202985.806451613 -1.16259966805877 -1.9506 -0.9946 2070430 Maybridge1_001661 Nc1nnc(Sc2cc3C(=O)NC(=O)c3cc2[N+](=O)[O-])s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D12 compound treatment 782960.0 -232000.0 -1.13 879370.0 -70100.0 -0.42 667610.0 -282575.806451613 -1.61845078986051 -1.8295 -0.906 2070431 Maybridge1_001662 CC(C)(C)OC(=O)C(C)(C)Sc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D13 compound treatment 444330.0 -571000.0 -2.79 437670.0 -512000.0 -3.04 247860.0 -702325.806451613 -4.02256573365091 -5.6892 -0.9871 2070432 Maybridge1_001663 Cc1ccc(N/C=C(\C#N)/c2nc3ccccc3[nH]2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D14 compound treatment 970560.0 -44400.0 -0.22 996820.0 47300.0 0.28 851630.0 -98555.806451613 -0.564477634514919 -0.2886 -0.4327 1038633 Maybridge1_001664 Cc1ccc(cc1)S(=O)(=O)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D15 compound treatment 773030.0 -242000.0 -1.18 703900.0 -246000.0 -1.46 707480.0 -242705.806451613 -1.39009566702805 -2.3281 -0.9962 2070433 Maybridge1_001665 Fc1ccc(NC(=O)CSc2ccccc2)c(F)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D16 compound treatment 1020570.0 5610.0 0.03 857960.0 -91500.0 -0.54 853310.0 -96875.806451613 -0.554855447247336 -0.6187 -0.7956 1513571 Maybridge1_001666 Cc1nn(C)c(=O)c(N)c1c2cc([nH]n2)c3ccsc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D17 compound treatment 1069340.0 54400.0 0.27 823430.0 -126000.0 -0.75 801690.0 -148495.806451613 -0.85050860602866 -0.7704 -0.6616 2070434 Maybridge1_001667 S=c1nc2sccn2c3ncccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D18 compound treatment 846590.0 -168000.0 -0.82 819400.0 -130000.0 -0.77 813600.0 -136585.806451613 -0.782294171292403 -1.3732 -0.9996 1025893 Maybridge1_001668 [O-][N+](=O)c1cccc(c1)C(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D19 compound treatment 921940.0 -93000.0 -0.45 709080.0 -240000.0 -1.43 820960.0 -129225.806451613 -0.740139827072517 -1.5151 -0.9058 2070435 Maybridge1_001669 [O-][N+](=O)c1ccc(cc1)N2N=C(CCC2=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D20 compound treatment 944720.0 -70200.0 -0.34 880190.0 -69300.0 -0.41 857960.0 -92225.806451613 -0.528222607488848 -0.741 -0.9844 1500830 Maybridge1_001670 CC(C)(Oc1ccc(cc1)C(=O)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D21 compound treatment 986980.0 -28000.0 -0.14 855150.0 -94300.0 -0.56 860210.0 -89975.806451613 -0.515335749541193 -0.7003 -0.9049 2070436 Maybridge1_001671 OC1=C(CCN(c2ccccc12)S(=O)(=O)c3ccc(Cl)cc3)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D22 compound treatment 532570.0 -482000.0 -2.36 518650.0 -431000.0 -2.56 435290.0 -514895.806451613 -2.9490618291491 -4.5425 -0.9956 2070437 Maybridge1_001672 Nc1ccc(Oc2cc(ccc2Cl)C(F)(F)F)cc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D23 mock treatment 1039550.0 24600.0 0.12 921320.0 -28200.0 -0.17 971270.0 21084.193548387 0.120759558755084 0.0424 0.1776 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 D24 mock treatment 1174880.0 160000.0 0.78 920810.0 -28700.0 -0.17 969640.0 19454.193548387 0.11142374610856 0.417 0.5165 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E01 compound treatment 1134880.0 120000.0 0.59 1040020.0 90500.0 0.54 1029880.0 79694.193548387 0.456447889560457 0.9127 0.9949 2070438 Maybridge1_001673 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E02 compound treatment 1156340.0 141000.0 0.69 1096320.0 147000.0 0.87 949120.0 -1065.80645161297 -0.00610439837405826 0.8994 0.8078 2070439 Maybridge1_001674 [O-][N+](=O)c1ccc(Oc2ccc(CC#N)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E03 compound treatment 1288430.0 273000.0 1.34 1008260.0 58800.0 0.35 981920.0 31734.193548387 0.181757353040653 1.0782 0.774 2070440 Maybridge1_001675 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3NC(=O)NC(=O)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E04 compound treatment 858280.0 -157000.0 -0.77 824180.0 -125000.0 -0.75 742290.0 -207895.806451613 -1.19072165584677 -1.5596 -0.9749 1006390 Maybridge1_001676 S=C(Nc1ccccc1)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E05 compound treatment 1010210.0 -4750.0 -0.02 1037960.0 88500.0 0.53 972720.0 22534.193548387 0.129064422765795 0.3649 0.6729 2070441 Maybridge1_001677 Fc1ccc(cc1F)c2csc(n2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E06 compound treatment 1125780.0 111000.0 0.54 1091680.0 142000.0 0.85 1045630.0 95444.193548387 0.546655895194046 1.1164 0.9765 2070442 Maybridge1_001678 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E07 compound treatment 755530.0 -259000.0 -1.27 872870.0 -76600.0 -0.46 728390.0 -221795.806451613 -1.27033380050117 -1.7282 -0.9335 2070443 Maybridge1_001679 Cc1onc(c1C(=O)Nc2ccc(F)c(Cl)c2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E08 compound treatment 988330.0 -26600.0 -0.13 968210.0 18700.0 0.11 969500.0 19314.193548387 0.110621897169595 0.0531 0.2603 1110266 Maybridge1_001680 CNc1ccccc1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E09 compound treatment 1181040.0 166000.0 0.81 1044320.0 94800.0 0.56 1101250.0 151064.193548387 0.865219023660091 1.2936 0.9849 2070444 Maybridge1_001681 Clc1cc(Cl)cc(c1)S(=O)(=O)Oc2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E10 compound treatment 945200.0 -69800.0 -0.34 954350.0 4870.0 0.03 966570.0 16384.193548387 0.0938403443755368 -0.1259 -0.3549 2070445 Maybridge1_001682 [O-][N+](=O)c1cccnc1NCc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E11 compound treatment 783400.0 -232000.0 -1.13 731130.0 -218000.0 -1.3 756530.0 -193655.806451613 -1.10916216376916 -2.0432 -0.9974 2070446 Maybridge1_001683 C/C(=N\O)/c1ccn(c1)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E12 compound treatment 1026290.0 11300.0 0.06 905390.0 -44100.0 -0.26 912260.0 -37925.806451613 -0.217219769018762 -0.2448 -0.7097 1178220 Maybridge1_001684 COc1ccc(Cl)c(OC)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E13 compound treatment 1063610.0 48700.0 0.24 887850.0 -61600.0 -0.37 764290.0 -185895.806451613 -1.0647168225808 -0.6891 -0.5987 2070447 Maybridge1_001685 Nc1ccc(Sc2cc(Cl)ccc2Cl)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E14 compound treatment 1000500.0 -14500.0 -0.07 936960.0 -12500.0 -0.07 1115360.0 165174.193548387 0.946033941722944 0.4624 0.486 1323451 Maybridge1_001686 COc1c(Cl)cc(Br)c(OC)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E15 compound treatment 1020580.0 5620.0 0.03 950190.0 712.0 0.0 944260.0 -5925.80645161297 -0.0339400115409942 -0.0013 -0.0295 2070448 Maybridge1_001687 C/C(=N\O)/c1ccc(C)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E16 compound treatment 922530.0 -92400.0 -0.45 871370.0 -78100.0 -0.46 902940.0 -47245.806451613 -0.270599998384161 -0.6851 -0.9759 2070449 Maybridge1_001688 COC(=O)c1c(OC)ccc(N/C=N/O)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E17 compound treatment 956740.0 -58200.0 -0.28 897860.0 -51600.0 -0.31 975250.0 25064.193548387 0.143554978591381 -0.2586 -0.5844 2070450 Maybridge1_001689 COc1ccc(Oc2ccc(N)cn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E18 compound treatment 1053000.0 38000.0 0.19 943430.0 -6050.0 -0.04 1023060.0 72874.193548387 0.417386391248008 0.3275 0.7146 2070451 Maybridge1_001690 CCOC(CN(c1ccc(F)cc1)S(=O)(=O)c2cc(Cl)cc(Cl)c2)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E19 compound treatment 1007460.0 -7500.0 -0.04 915520.0 -34000.0 -0.2 931940.0 -18245.806451613 -0.104502718169935 -0.1981 -0.86 2070452 Maybridge1_001691 OCCNc1ccc(NCCO)nn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E20 compound treatment 936320.0 -78600.0 -0.38 883240.0 -66200.0 -0.39 958800.0 8614.19354838703 0.0493377282629664 -0.4208 -0.7616 1098980 Maybridge1_001692 COC(=O)c1ccncc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E21 compound treatment 885130.0 -130000.0 -0.63 797120.0 -152000.0 -0.91 826690.0 -123495.806451613 -0.707321295499154 -1.2977 -0.9885 1078393 Maybridge1_001693 Nc1ncc(Br)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E22 compound treatment 910350.0 -105000.0 -0.51 879120.0 -70400.0 -0.42 910690.0 -39495.806451613 -0.226211932120015 -0.6672 -0.9557 2070453 Maybridge1_001694 [O-][N+](=O)c1cccnc1Oc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E23 mock treatment 1009520.0 -5440.0 -0.03 935650.0 -13800.0 -0.08 966580.0 16394.193548387 0.0938976192997486 -0.0086 -0.0674 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 E24 mock treatment 960410.0 -54500.0 -0.27 899450.0 -50000.0 -0.3 974600.0 24414.193548387 0.139832108517614 -0.2449 -0.5787 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F01 compound treatment 1006630.0 -8330.0 -0.04 904800.0 -44700.0 -0.27 825500.0 -124685.806451613 -0.714137011480359 -0.5892 -0.7722 2070454 Maybridge1_001695 OC(=O)CSc1ccc(cn1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F02 compound treatment 1215160.0 200000.0 0.98 1017280.0 67800.0 0.4 1044880.0 94694.193548387 0.542360275878161 1.1106 0.9342 2070455 Maybridge1_001696 CC(C)(C)c1ccc(cc1)C(=O)NNC(=O)c2cc(cc(c2)C(C)(C)C)C(=O)NNC(=O)c3ccc(cc3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F03 compound treatment 1130090.0 115000.0 0.56 1053540.0 104000.0 0.62 958720.0 8534.19354838703 0.048879528869272 0.7103 0.8479 2070456 Maybridge1_001697 CS(=O)(=O)NCc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F04 compound treatment 763170.0 -252000.0 -1.23 678990.0 -270000.0 -1.61 565200.0 -384985.806451613 -2.20500328871357 -2.912 -0.9727 1918990 Maybridge1_001698 c1csc(c1)c2cnc3ccccc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F05 compound treatment 706970.0 -308000.0 -1.5 677950.0 -272000.0 -1.61 671400.0 -278785.806451613 -1.59674359358423 -2.7229 -0.9995 2070457 Maybridge1_001699 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)c(C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F06 compound treatment 1131430.0 116000.0 0.57 1060020.0 111000.0 0.66 881870.0 -68315.806451613 -0.391278263698429 0.4822 0.5057 1570677 Maybridge1_001700 OC(=O)c1cccnc1Oc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F07 compound treatment 1131000.0 116000.0 0.57 957120.0 7640.0 0.05 1020160.0 69974.193548387 0.400776663226585 0.585 0.8407 1524701 Maybridge1_001701 Brc1ccc(cc1)n2c(=S)[nH]c(=O)c3cccnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F08 compound treatment 1081400.0 66400.0 0.32 928550.0 -20900.0 -0.12 906820.0 -43365.806451613 -0.248377327789982 -0.0278 -0.0651 1346644 Maybridge1_001702 Cc1ccc(Sc2ncccc2C(=O)NCC(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F09 compound treatment 1194240.0 179000.0 0.88 1193800.0 244000.0 1.45 934610.0 -15575.806451613 -0.0892103134053834 1.293 0.7611 2070458 Maybridge1_001703 COc1ccccc1N2CC(C)(C)C(=O)N(C(=O)c3c(F)cccc3Cl)C2=S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F10 compound treatment 1062030.0 47100.0 0.23 1035550.0 86100.0 0.51 832070.0 -118115.806451613 -0.676507386273205 0.0377 0.0429 2070459 Maybridge1_001704 Cc1c(Cl)cccc1SCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F11 compound treatment 947520.0 -67400.0 -0.33 918080.0 -31400.0 -0.19 842520.0 -107665.806451613 -0.616655090471871 -0.6541 -0.9038 1538792 Maybridge1_001705 Nc1cc2C(=O)NC(=O)c2cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F12 compound treatment 789960.0 -225000.0 -1.1 742850.0 -207000.0 -1.23 601550.0 -348635.806451613 -1.99680893920367 -2.4969 -0.9643 2070460 Maybridge1_001706 CC(C)(C)OC(=O)C(C)(C)Sc1ccc(cn1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F13 compound treatment 926830.0 -88100.0 -0.43 911460.0 -38000.0 -0.23 913680.0 -36505.806451613 -0.209086729780686 -0.4998 -0.9442 2070461 Maybridge1_001707 COc1ccc(Oc2ccc(cc2C(=O)O)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F14 compound treatment 976960.0 -38000.0 -0.19 897930.0 -51500.0 -0.31 874820.0 -75365.806451613 -0.43165708526775 -0.5334 -0.9507 1013662 Maybridge1_001708 Cc1ccc(cc1)S(=O)(=O)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F15 compound treatment 53830.0 -961000.0 -4.7 79840.0 -870000.0 -5.17 76710.0 -873475.806451613 -5.00282606153591 -8.5852 -0.9992 2070462 Maybridge1_001709 Fc1ccc(NC(=O)CSc2ssc(=S)c2c3ccccc3)c(F)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F16 compound treatment 927740.0 -87200.0 -0.43 901550.0 -47900.0 -0.29 779710.0 -170475.806451613 -0.976398889446201 -0.9743 -0.8835 2070463 Maybridge1_001710 CC(C)(C(=O)Oc1ccc(Cl)cc1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F17 compound treatment 743320.0 -272000.0 -1.33 877670.0 -71800.0 -0.43 640490.0 -309695.806451613 -1.77378038432291 -2.0369 -0.9028 2070464 Maybridge1_001711 O/N=C/C(=O)Nc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F18 compound treatment 1012690.0 -2270.0 -0.01 853440.0 -96000.0 -0.57 859880.0 -90305.806451613 -0.517225822040182 -0.6347 -0.8237 2070465 Maybridge1_001712 COC(=O)c1ccc(cc1)c2ccc(cc2)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F19 compound treatment 970950.0 -44000.0 -0.22 878480.0 -71000.0 -0.42 880330.0 -69855.806451613 -0.400098602027046 -0.5989 -0.9658 2070466 Maybridge1_001713 Cn1c(SCC(=O)c2ccc(Cl)cc2)nnc1SCC(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F20 compound treatment 692420.0 -323000.0 -1.58 632040.0 -317000.0 -1.89 631770.0 -318415.806451613 -1.82372411823561 -3.0526 -0.9971 2070467 Maybridge1_001714 COc1ccc(N)c(Sc2ccc(Cl)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F21 compound treatment 804000.0 -211000.0 -1.03 784440.0 -165000.0 -0.98 793600.0 -156585.806451613 -0.896844019716008 -1.6795 -0.9984 1048764 Maybridge1_001715 CCOC(=O)c1cnn(c1C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F22 compound treatment 985790.0 -29200.0 -0.14 876730.0 -72700.0 -0.43 912220.0 -37965.806451613 -0.217448868715609 -0.4576 -0.9066 1408448 Maybridge1_001716 Cc1nc(cs1)c2cc(C#N)c(=O)[nH]c2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F23 mock treatment 1040910.0 26000.0 0.13 973680.0 24200.0 0.14 938760.0 -11425.806451613 -0.0654412198574855 0.1185 0.5848 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 F24 mock treatment 1047220.0 32300.0 0.16 1008640.0 59200.0 0.35 876320.0 -73865.806451613 -0.423065846635979 0.0499 0.0871 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G01 compound treatment 1267380.0 252000.0 1.23 1021220.0 71700.0 0.43 1044100.0 93914.193548387 0.53789283178964 1.2689 0.899 2070468 Maybridge1_001717 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)NC(=O)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G02 compound treatment 1160000.0 145000.0 0.71 1127220.0 178000.0 1.06 1028960.0 78774.193548387 0.451178596532971 1.2799 0.9479 1111505 Maybridge1_001718 CC(=O)Nc1ccc(cc1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G03 compound treatment 940340.0 -74600.0 -0.36 914330.0 -35100.0 -0.21 946930.0 -3255.80645161297 -0.018647606776443 -0.3419 -0.8129 2070469 Maybridge1_001719 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3NS(=O)(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G04 compound treatment 1115840.0 101000.0 0.49 1024640.0 75200.0 0.45 1038840.0 88654.193548387 0.507766221654232 0.8358 0.9986 2070470 Maybridge1_001720 [O-][N+](=O)c1cccnc1Oc2cncc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G05 compound treatment 1120160.0 105000.0 0.51 1182340.0 233000.0 1.38 990800.0 40614.193548387 0.232617485740734 1.2305 0.823 1029371 Maybridge1_001721 OC(=O)CCC(N1C(=O)c2ccccc2C1=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G06 compound treatment 966120.0 -48800.0 -0.24 909460.0 -40000.0 -0.24 890370.0 -59815.806451613 -0.342594578118397 -0.473 -0.9842 2070471 Maybridge1_001722 CC(C)(C)c1ccc(Oc2ncccc2[N+](=O)[O-])c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G07 compound treatment 993410.0 -21500.0 -0.11 1033180.0 83700.0 0.5 988060.0 37874.193548387 0.2169241565067 0.3518 0.6361 2070472 Maybridge1_001723 Cc1onc(c1C(=O)Nc2cccc(Cl)c2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G08 compound treatment 1115530.0 101000.0 0.49 1018460.0 69000.0 0.41 1096750.0 146564.193548387 0.839445307764779 1.0052 0.9522 2070473 Maybridge1_001724 CCOC(=O)CC(=O)CSc1nnc(N)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G09 compound treatment 930580.0 -84400.0 -0.41 830270.0 -119000.0 -0.71 902370.0 -47815.806451613 -0.273864669064234 -0.8054 -0.9316 1396369 Maybridge1_001725 CN(c1c2CCCCc2nn1C)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G10 compound treatment 1248320.0 233000.0 1.14 972270.0 22800.0 0.14 833660.0 -116525.806451613 -0.667400673323528 0.3512 0.2644 2070474 Maybridge1_001726 [O-][N+](=O)c1cccnc1NCc2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G11 compound treatment 1003310.0 -11600.0 -0.06 1050290.0 101000.0 0.6 952580.0 2394.19354838703 0.0137127254032253 0.3212 0.5332 1274708 Maybridge1_001727 COc1cccc(OC)c1C(=O)NC(=O)Oc2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G12 compound treatment 1154010.0 139000.0 0.68 1182190.0 233000.0 1.38 886880.0 -63305.806451613 -0.362583526668316 0.9819 0.62 2070475 Maybridge1_001728 Cc1ccc(cc1)n2ncc(C#N)c2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G13 compound treatment 994800.0 -20200.0 -0.1 955680.0 6200.0 0.04 903640.0 -46545.806451613 -0.266590753689335 -0.1895 -0.6612 1070439 Maybridge1_001729 [O-][N+](=O)c1ccc(Oc2cccc(c2)C(F)(F)F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G14 compound treatment 915680.0 -99300.0 -0.49 879880.0 -69600.0 -0.41 1063040.0 112854.193548387 0.646371538246794 -0.1458 -0.1606 2070476 Maybridge1_001730 Nc1c(C#N)cnn1c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G15 compound treatment 876970.0 -138000.0 -0.67 845240.0 -104000.0 -0.62 808680.0 -141505.806451613 -0.81047343400461 -1.215 -0.9935 1575604 Maybridge1_001731 Cc1cc(Cl)ccc1Oc2ccc(N)cn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G16 compound treatment 635840.0 -379000.0 -1.85 667410.0 -282000.0 -1.68 702270.0 -247915.806451613 -1.4199359025424 -2.8576 -0.9943 2070477 Maybridge1_001732 Oc1c(cnn(c2ccccc2)c1=O)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G17 compound treatment 858000.0 -157000.0 -0.77 849640.0 -99800.0 -0.59 794980.0 -155205.806451613 -0.888940080174779 -1.2988 -0.9872 1065659 Maybridge1_001733 Nc1ccc(Oc2ccc(F)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G18 compound treatment 1018050.0 3090.0 0.02 969330.0 19900.0 0.12 1178940.0 228754.193548387 1.31018790986158 0.8333 0.6334 2070478 Maybridge1_001734 CCOC(CN(c1ccc(F)cc1)S(=O)(=O)c2ccc(F)cc2F)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G19 compound treatment 985440.0 -29500.0 -0.14 999970.0 50500.0 0.3 890300.0 -59885.806451613 -0.34299550258788 -0.1079 -0.2258 2070479 Maybridge1_001735 Cc1ccc(Oc2ccc(cn2)[N+](=O)[O-])c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G20 compound treatment 976340.0 -38600.0 -0.19 956890.0 7410.0 0.04 921350.0 -28835.806451613 -0.165156862910233 -0.1788 -0.7025 1049801 Maybridge1_001736 NC(=O)c1ncccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G21 compound treatment 977620.0 -37300.0 -0.18 953060.0 3580.0 0.02 886670.0 -63515.806451613 -0.363786300076764 -0.3031 -0.7437 1725682 Maybridge1_001737 CC(=O)Nc1ncccc1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G22 compound treatment 877880.0 -137000.0 -0.67 903910.0 -45600.0 -0.27 876610.0 -73575.806451613 -0.421404873833837 -0.7864 -0.9402 2070480 Maybridge1_001738 Nc1cccnc1Oc2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G23 mock treatment 978530.0 -36400.0 -0.18 954270.0 4790.0 0.03 997870.0 47684.193548387 0.273110857158478 0.0714 0.2181 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 G24 mock treatment 1059390.0 44400.0 0.22 979430.0 30000.0 0.18 1041300.0 91114.193548387 0.521855853010336 0.5295 0.8934 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H01 compound treatment 1014280.0 -678.0 0.0 962370.0 12900.0 0.08 1077570.0 127384.193548387 0.729592003126543 0.4636 0.6319 2070481 Maybridge1_001739 COC(=O)CS(=O)(=O)c1ccc(cn1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H02 compound treatment 1255420.0 240000.0 1.17 997940.0 48500.0 0.29 838770.0 -111415.806451613 -0.638133187051297 0.4763 0.3482 2070482 Maybridge1_001740 CC(C)(C)c1cc(cc(c1)C(=O)NNC(=O)c2ccc(Cl)cc2Cl)C(=O)NNC(=O)c3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H03 compound treatment 1088730.0 73800.0 0.36 914640.0 -34800.0 -0.21 851950.0 -98235.806451613 -0.562644836940141 -0.2364 -0.3379 1025749 Maybridge1_001741 CS(=O)(=O)NCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H04 compound treatment 1097600.0 82600.0 0.4 986830.0 37400.0 0.22 935470.0 -14715.806451613 -0.0842846699231684 0.3127 0.6675 2070483 Maybridge1_001742 COC(=O)CNC(=O)c1cc(ccc1Oc2ccc(OC)cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H05 compound treatment 946120.0 -68800.0 -0.34 940920.0 -8560.0 -0.05 856410.0 -93775.806451613 -0.537100220741678 -0.5337 -0.8394 2070484 Maybridge1_001743 [O-][N+](=O)c1ccc(SCc2ccccc2)c(C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H06 compound treatment 1041370.0 26400.0 0.13 962880.0 13400.0 0.08 986830.0 36644.193548387 0.209879340828648 0.2417 0.9334 2070485 Maybridge1_001744 OC(=O)c1cccnc1Sc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H07 compound treatment 1105390.0 90400.0 0.44 1039040.0 89600.0 0.53 840350.0 -109835.806451613 -0.629083749025832 0.1994 0.2132 1297323 Maybridge1_001745 CSc1nc(=O)c2cccnc2n1c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H08 compound treatment 1005660.0 -9300.0 -0.05 853600.0 -95900.0 -0.57 951560.0 1374.19354838703 0.0078706831336215 -0.3509 -0.6134 1641310 Maybridge1_001746 NC(=O)c1cccnc1Oc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H09 compound treatment 889160.0 -126000.0 -0.61 845790.0 -104000.0 -0.62 1118850.0 168664.193548387 0.966022890272863 -0.1531 -0.1177 1733777 Maybridge1_001747 COC(=O)c1ccccc1C(=O)c2cc(C)c(O)c(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H10 compound treatment 1026530.0 11600.0 0.06 861780.0 -87700.0 -0.52 822720.0 -127465.806451613 -0.73005944041124 -0.6899 -0.7675 2070486 Maybridge1_001748 OC(=O)CSc1cccc2cccc(Cl)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H11 compound treatment 942370.0 -72600.0 -0.35 890130.0 -59300.0 -0.35 839850.0 -110335.806451613 -0.631947495236422 -0.7734 -0.9595 2070487 Maybridge1_001749 CCCCNC(=O)Nc1nnc(s1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H12 compound treatment 961710.0 -53200.0 -0.26 923240.0 -26200.0 -0.16 1074240.0 124054.193548387 0.710519453364012 0.1699 0.22 2070488 Maybridge1_001750 CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H13 compound treatment 933820.0 -81100.0 -0.4 922210.0 -27300.0 -0.16 1132910.0 182724.193548387 1.04655143371466 0.2817 0.2491 2070489 Maybridge1_001751 Cc1nc2ccccn2c(=O)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H14 compound treatment 963520.0 -51400.0 -0.25 797280.0 -152000.0 -0.91 807620.0 -142565.806451613 -0.816544575971061 -1.1391 -0.9152 1038637 Maybridge1_001752 Cc1ccc(cc1)S(=O)(=O)N2CCCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H15 compound treatment 971040.0 -43900.0 -0.21 950400.0 922.0 0.01 882530.0 -67655.806451613 -0.38749811870045 -0.3444 -0.7776 2070490 Maybridge1_001753 [O-][N+](=O)c1cc(ccc1Oc2ccc(SC(F)(F)F)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H16 compound treatment 946910.0 -68000.0 -0.33 1025090.0 75600.0 0.45 878770.0 -71415.806451613 -0.409033490204088 -0.1685 -0.2432 1597019 Maybridge1_001754 Cc1onc2c(=O)n(nc(c3ccccc3)c12)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H17 compound treatment 892480.0 -122000.0 -0.6 787680.0 -162000.0 -0.96 773390.0 -176795.806451613 -1.01259664154806 -1.4856 -0.9776 2070491 Maybridge1_001755 Cn1ccnc1SCC(=O)c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H18 compound treatment 920340.0 -94600.0 -0.46 855090.0 -94400.0 -0.56 778740.0 -171445.806451613 -0.981954557094746 -1.1579 -0.9476 1060482 Maybridge1_001756 N#Cc1ccc(cc1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H19 compound treatment 942120.0 -72800.0 -0.36 849800.0 -99700.0 -0.59 1034560.0 84374.193548387 0.483252554091581 -0.2687 -0.3185 2070492 Maybridge1_001757 COC(=O)c1ccc(Cl)cc1N(CCCC#N)S(=O)(=O)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H20 compound treatment 771970.0 -243000.0 -1.19 690050.0 -259000.0 -1.54 780060.0 -170125.806451613 -0.974394267098788 -2.1387 -0.9824 2070493 Maybridge1_001758 COc1cc(OC)c([N+](=O)[O-])c(OC)c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H21 compound treatment 695530.0 -319000.0 -1.56 676730.0 -273000.0 -1.62 717070.0 -233115.806451613 -1.33516901470893 -2.6083 -0.9967 2070494 Maybridge1_001759 CCOC(=O)c1cnn(c1C)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H22 compound treatment 986840.0 -28100.0 -0.14 906570.0 -42900.0 -0.26 931200.0 -18985.806451613 -0.108741062561608 -0.2894 -0.935 1644615 Maybridge1_001760 COc1nc(C)c(cc1C#N)c2csc(C)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H23 mock treatment 1044290.0 29300.0 0.14 972360.0 22900.0 0.14 924290.0 -25895.806451613 -0.148318035191963 0.0757 0.3062 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 H24 mock treatment 1114480.0 99500.0 0.49 1017340.0 67900.0 0.4 1012180.0 61994.193548387 0.355071273705567 0.7187 0.9916 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I01 compound treatment 1018280.0 3320.0 0.02 949310.0 -168.0 0.0 850630.0 -99555.806451613 -0.570205126936099 -0.3204 -0.5617 2070495 Maybridge1_001761 COc1ccc(cc1OC)S(=O)(=O)Nc2ccccc2c3nnc(o3)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I02 compound treatment 1161450.0 146000.0 0.72 1056480.0 107000.0 0.64 990720.0 40534.193548387 0.232159286347039 0.9146 0.9282 2070496 Maybridge1_001762 CC(C)(C)c1cc(OC(=O)c2ccc(Cl)cc2)c(cc1OC(=O)c3ccc(Cl)cc3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I03 compound treatment 951370.0 -63600.0 -0.31 872130.0 -77300.0 -0.46 856130.0 -94055.806451613 -0.538703918619608 -0.7559 -0.9773 1257183 Maybridge1_001763 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3NS(=O)(=O)c4ccc(C)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I04 compound treatment 1050740.0 35800.0 0.17 967040.0 17600.0 0.1 901680.0 -48505.806451613 -0.277816638834848 8.0E-4 0.0024 2070497 Maybridge1_001764 [O-][N+](=O)c1ccc(Oc2cncc(Cl)c2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I05 compound treatment 769520.0 -245000.0 -1.2 679040.0 -270000.0 -1.61 689140.0 -261045.806451613 -1.4951378780325 -2.484 -0.9928 1460964 Maybridge1_001765 Cc1ccc(COc2ccc(CC#N)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I06 compound treatment 876330.0 -139000.0 -0.68 917350.0 -32100.0 -0.19 890020.0 -60165.806451613 -0.34459920046581 -0.7003 -0.8937 2070498 Maybridge1_001766 CN(C)/C=N/c1c(C#N)cnn1c2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I07 compound treatment 1335730.0 321000.0 1.57 928160.0 -21300.0 -0.13 976860.0 26674.193548387 0.152776241389481 0.9199 0.5823 2070499 Maybridge1_001767 Clc1ccc(cc1)C(=O)NC(=O)Oc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I08 compound treatment 980520.0 -34400.0 -0.17 880230.0 -69200.0 -0.41 919910.0 -30275.806451613 -0.173404451996733 -0.435 -0.9111 2070500 Maybridge1_001768 CCCn1c(SC)nnc1SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I09 compound treatment 909060.0 -106000.0 -0.52 834770.0 -115000.0 -0.68 825990.0 -124195.806451613 -0.71133054019398 -1.1032 -0.9911 1949637 Maybridge1_001769 Clc1ccc(cc1)S(=O)(=O)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I10 compound treatment 608410.0 -407000.0 -1.99 666210.0 -283000.0 -1.68 519040.0 -431145.806451613 -2.46938433887525 -3.545 -0.9878 2070501 Maybridge1_001770 Nc1cc(Cl)c(cc1Cl)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I11 compound treatment 1025600.0 10600.0 0.05 997560.0 48100.0 0.29 958960.0 8774.19354838703 0.0502541270503552 0.2241 0.7599 2070502 Maybridge1_001771 [O-][N+](=O)c1cc(ccc1Oc2ccc(Cl)cc2C3CCCCC3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I12 compound treatment 1013950.0 -1010.0 0.0 992010.0 42500.0 0.25 900960.0 -49225.806451613 -0.281940433378098 -0.0196 -0.0517 1210951 Maybridge1_001772 COc1c(Cl)cc(Cl)c(OC)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I13 compound treatment 940360.0 -74600.0 -0.36 888410.0 -61100.0 -0.36 780240.0 -169945.806451613 -0.973363318462976 -0.9821 -0.892 2070503 Maybridge1_001773 [O-][N+](=O)c1ccc(Oc2ccc(F)cc2F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I14 compound treatment 880700.0 -134000.0 -0.66 827550.0 -122000.0 -0.73 1024960.0 74774.193548387 0.428268626848251 -0.5501 -0.5153 2070504 Maybridge1_001774 N#CCSc1nnc(s1)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I15 compound treatment 860320.0 -155000.0 -0.76 833310.0 -116000.0 -0.69 951400.0 1214.19354838703 0.00695428434623266 -0.831 -0.8117 2070505 Maybridge1_001775 [O-][N+](=O)c1ccc(Oc2cccnc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I16 compound treatment 1106100.0 91100.0 0.45 870430.0 -79000.0 -0.47 873940.0 -76245.806451613 -0.436697278598388 -0.2664 -0.3411 2070506 Maybridge1_001776 COC(=O)C1=NN(C(=O)C1)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I17 compound treatment 953520.0 -61400.0 -0.3 845670.0 -104000.0 -0.62 814560.0 -135625.806451613 -0.77679577856807 -0.9782 -0.9436 1562566 Maybridge1_001777 Cc1cccc(Oc2ccc(N)cn2)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I18 compound treatment 886020.0 -129000.0 -0.63 1075360.0 126000.0 0.75 871450.0 -78735.806451613 -0.450958734727127 -0.1919 -0.1781 2070507 Maybridge1_001778 CCOC(CN(C(=O)c1ccc(F)cc1)c2ccc(F)cc2)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I19 compound treatment 898840.0 -116000.0 -0.57 959880.0 10400.0 0.06 801680.0 -148505.806451613 -0.850565880952872 -0.7829 -0.7644 2070508 Maybridge1_001779 Cc1ccc(Oc2ncccc2[N+](=O)[O-])c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I20 compound treatment 917440.0 -97500.0 -0.48 894850.0 -54600.0 -0.32 1002290.0 52104.193548387 0.298426373660095 -0.2903 -0.4472 1002904 Maybridge1_001780 OC(=O)c1nccnc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I21 compound treatment 1016690.0 1730.0 0.01 941290.0 -8190.0 -0.05 886450.0 -63735.806451613 -0.365046348409423 -0.234 -0.6352 2070509 Maybridge1_001781 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(C)nc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I22 compound treatment 850910.0 -164000.0 -0.8 849620.0 -99900.0 -0.59 912550.0 -37635.806451613 -0.215558796216619 -0.93 -0.9113 2070510 Maybridge1_001782 Nc1ccc(Oc2ccccc2F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I23 mock treatment 995170.0 -19800.0 -0.1 867520.0 -82000.0 -0.49 914190.0 -35995.806451613 -0.206165708645884 -0.4562 -0.8481 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 I24 mock treatment 1024730.0 9770.0 0.05 936990.0 -12500.0 -0.07 935150.0 -15035.806451613 -0.0861174674979461 -0.065 -0.5273 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J01 compound treatment 1008480.0 -6480.0 -0.03 1108640.0 159000.0 0.95 926200.0 -23985.806451613 -0.137378524667509 0.4489 0.4691 2070511 Maybridge1_001783 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC(=O)NNC(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J02 compound treatment 1060960.0 46000.0 0.22 1051070.0 102000.0 0.6 987950.0 37764.193548387 0.21629413234037 0.6034 0.8875 2070512 Maybridge1_001784 CC(C)(C)c1cc(cc(c1)C(=O)NNC(=O)c2ccc(cc2)C(F)(F)F)C(=O)NNC(=O)c3ccc(cc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J03 compound treatment 1060720.0 45800.0 0.22 982730.0 33300.0 0.2 1073600.0 123414.193548387 0.706853858214457 0.6514 0.8489 2070513 Maybridge1_001785 COc1ccc(/C=C/2\C(=NN(C2=O)c3ccc(Cl)c(Cl)c3)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J04 compound treatment 1256100.0 241000.0 1.18 1115920.0 166000.0 0.99 1048280.0 98094.193548387 0.561833750110174 1.576 0.9621 1139373 Maybridge1_001786 OC(=O)c1cccnc1Sc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J05 compound treatment 925500.0 -89500.0 -0.44 794010.0 -155000.0 -0.92 938440.0 -11745.806451613 -0.0672740174322631 -0.8249 -0.805 2070514 Maybridge1_001787 CC/1=NN(C(=O)\C1=C\c2ccc(OCc3ccccc3)cc2)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J06 compound treatment 1037540.0 22600.0 0.11 1025980.0 76500.0 0.45 1183060.0 232874.193548387 1.33378517863685 1.0964 0.7756 1243528 Maybridge1_001788 COC(=O)CNC(=O)c1cccnc1Sc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J07 compound treatment 933950.0 -81000.0 -0.4 896090.0 -53400.0 -0.32 865780.0 -84405.806451613 -0.483433616755219 -0.6909 -0.9859 1168374 Maybridge1_001789 Brc1ccc(cc1)n2c(SCC#C)nc(=O)c3cccnc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J08 compound treatment 1127640.0 113000.0 0.55 1086940.0 137000.0 0.82 847880.0 -102305.806451613 -0.585955731094345 0.4515 0.3938 1458502 Maybridge1_001790 Cc1ccc(Oc2ncccc2C(=O)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J09 compound treatment 995370.0 -19600.0 -0.1 902400.0 -47100.0 -0.28 809890.0 -140295.806451613 -0.803543168174982 -0.6808 -0.7951 2070515 Maybridge1_001791 Cc1cc(cc(C)c1OC(=O)c2ccc(cc2)C(F)(F)F)c3nn(C)c(=O)c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J10 compound treatment 419710.0 -595000.0 -2.91 387840.0 -562000.0 -3.34 382470.0 -567715.806451613 -3.25158797883584 -5.4846 -0.9983 2070516 Maybridge1_001792 [O-][N+](=O)c1cc(Br)c(Oc2cncc(Cl)c2)cc1Oc3cncc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J11 compound treatment 824810.0 -190000.0 -0.93 840340.0 -109000.0 -0.65 828380.0 -121805.806451613 -0.69764183330736 -1.3139 -0.9873 2070517 Maybridge1_001793 COC(=O)COc1ccc(SC(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J12 compound treatment 980710.0 -34200.0 -0.17 1023840.0 74400.0 0.44 893850.0 -56335.806451613 -0.32266290449269 -0.0276 -0.0482 2070518 Maybridge1_001794 CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J13 compound treatment 1173350.0 158000.0 0.77 1085650.0 136000.0 0.81 858590.0 -91595.806451613 -0.524614287263505 0.6114 0.4943 2070519 Maybridge1_001795 CCOC(=O)c1cnc2nc(SC)nn2c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J14 compound treatment 322770.0 -692000.0 -3.38 287280.0 -662000.0 -3.94 375910.0 -574275.806451613 -3.28916032911878 -6.125 -0.9967 1386298 Maybridge1_001796 O=C(OCCS(=O)(=O)c1ccccn1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J15 compound treatment 841370.0 -174000.0 -0.85 843680.0 -106000.0 -0.63 856650.0 -93535.806451613 -0.535725622560594 -1.1622 -0.9815 2070520 Maybridge1_001797 Fc1ccc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)c(F)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J16 compound treatment 921930.0 -93000.0 -0.45 872890.0 -76600.0 -0.46 833600.0 -116585.806451613 -0.667744322868799 -0.9109 -0.9823 2070521 Maybridge1_001798 Cc1nn(C)c(=O)c2noc(/C=C/c3ccc(cc3)C(F)(F)F)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J17 compound treatment 300420.0 -715000.0 -3.49 264890.0 -685000.0 -4.07 321240.0 -628945.806451613 -3.6022823397847 -6.4457 -0.9977 2070522 Maybridge1_001799 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(OC(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J18 compound treatment 941450.0 -73500.0 -0.36 705550.0 -244000.0 -1.45 732560.0 -217625.806451613 -1.24645015710485 -1.7645 -0.9067 2070523 Maybridge1_001800 CN(C)/C=N\c1cc(C)nc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J19 compound treatment 987610.0 -27300.0 -0.13 819680.0 -130000.0 -0.77 827690.0 -122495.806451613 -0.701593803077974 -0.9278 -0.8823 1098259 Maybridge1_001801 Nc1ncccc1OCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J20 compound treatment 864320.0 -151000.0 -0.74 644480.0 -305000.0 -1.81 788010.0 -162175.806451613 -0.928860702350406 -2.0083 -0.927 1711015 Maybridge1_001802 Fc1ccc(NC(=O)c2c(F)cccc2NC(=O)c3cccs3)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J21 compound treatment 868290.0 -147000.0 -0.72 767410.0 -182000.0 -1.08 808490.0 -141695.806451613 -0.811561657564634 -1.5074 -0.9845 2070524 Maybridge1_001803 Nc1nc(Oc2ccc(Cl)cc2)ncc1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J22 compound treatment 957300.0 -57700.0 -0.28 902120.0 -47400.0 -0.28 886410.0 -63775.806451613 -0.365275448106271 -0.5361 -0.992 1159034 Maybridge1_001804 Cc1nc(cs1)c2cc(C#N)c(Sc3ccccc3)nc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J23 mock treatment 1038880.0 23900.0 0.12 961840.0 12400.0 0.07 883370.0 -66815.806451613 -0.382687025066659 -0.111 -0.2729 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 J24 mock treatment 963490.0 -51500.0 -0.25 985060.0 35600.0 0.21 985850.0 35664.193548387 0.204266398255892 0.0949 0.2453 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K01 compound treatment 1089450.0 74500.0 0.36 1083270.0 134000.0 0.8 1063930.0 113744.193548387 0.651469006501644 1.0456 0.9586 2070525 Maybridge1_001805 [O-][N+](=O)c1ccccc1C(=O)NNC(=O)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K02 compound treatment 1027330.0 12400.0 0.06 987640.0 38200.0 0.23 1075220.0 125034.193548387 0.716132395936769 0.5794 0.7688 2070526 Maybridge1_001806 CC(C)(C)c1cc(OC(=O)c2ccc(cc2)C(F)(F)F)c(cc1OC(=O)c3ccc(cc3)C(F)(F)F)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K03 compound treatment 910440.0 -105000.0 -0.51 944330.0 -5150.0 -0.03 907450.0 -42735.806451613 -0.244769007564639 -0.4538 -0.8002 2070527 Maybridge1_001807 CS/C(=N\S(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F)/N4CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K04 compound treatment 744520.0 -270000.0 -1.32 690850.0 -259000.0 -1.54 678340.0 -271845.806451613 -1.55699479618124 -2.5497 -0.9974 2070528 Maybridge1_001808 COc1ccc(Oc2c(O)occ2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K05 compound treatment 874000.0 -141000.0 -0.69 904800.0 -44700.0 -0.27 869470.0 -80715.806451613 -0.462299169721064 -0.8179 -0.9391 1589783 Maybridge1_001809 Clc1ccc(COc2ccc(CC#N)cc2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K06 compound treatment 1310000.0 295000.0 1.44 1189000.0 240000.0 1.42 893010.0 -57175.806451613 -0.327473998126481 1.4655 0.7139 2070529 Maybridge1_001810 CC1=NN(C(=O)C1CCO)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K07 compound treatment 1249940.0 235000.0 1.15 1238630.0 289000.0 1.72 1033300.0 83114.193548387 0.476035913640894 1.9304 0.9099 1044477 Maybridge1_001811 OC(=O)c1cc2cc(ccc2oc1=O)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K08 compound treatment 882160.0 -133000.0 -0.65 848880.0 -101000.0 -0.6 832240.0 -117945.806451613 -0.675533712561604 -1.11 -0.9988 2070530 Maybridge1_001812 COC(=O)c1cc2ccccc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K09 compound treatment 1083950.0 69000.0 0.34 1047620.0 98100.0 0.58 908930.0 -41255.806451613 -0.236292318781292 0.3951 0.5533 2070531 Maybridge1_001813 COc1cc(CC=C)ccc1Oc2ccc(cn2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K10 compound treatment 919610.0 -95300.0 -0.47 780800.0 -169000.0 -1.0 898520.0 -51665.806451613 -0.295915514885778 -1.0189 -0.89 2070532 Maybridge1_001814 CN(C)/C=N/c1cc(Cl)c(cc1Cl)n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K11 compound treatment 1095330.0 80400.0 0.39 978620.0 29100.0 0.17 1010880.0 60694.193548387 0.347625533558033 0.5275 0.955 2070533 Maybridge1_001815 Cc1cccc(NC(=O)C(F)(F)F)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K12 compound treatment 1002250.0 -12700.0 -0.06 870790.0 -78700.0 -0.47 933250.0 -16935.806451613 -0.0969997030981885 -0.362 -0.7512 2070534 Maybridge1_001816 COc1c(Cl)cc([N+](=O)[O-])c(OC)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K13 compound treatment 795040.0 -220000.0 -1.07 760560.0 -189000.0 -1.12 935750.0 -14435.806451613 -0.082680972045238 -1.3167 -0.8458 2070535 Maybridge1_001817 [O-][N+](=O)c1ccc(Oc2ccc(Br)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K14 compound treatment 1257760.0 243000.0 1.19 1092260.0 143000.0 0.85 899630.0 -50555.806451613 -0.289557998298268 1.0079 0.6777 2070536 Maybridge1_001818 FC(F)(F)c1cccc(c1)C(=O)CN2C(=O)c3ccccc3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K15 compound treatment 843840.0 -171000.0 -0.84 810880.0 -139000.0 -0.82 845380.0 -104805.806451613 -0.600274462147296 -1.3051 -0.9898 2070537 Maybridge1_001819 Nc1ccc(Oc2ccc(F)cc2F)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K16 compound treatment 787630.0 -227000.0 -1.11 747680.0 -202000.0 -1.2 733800.0 -216385.806451613 -1.23934806650259 -2.0496 -0.999 1003999 Maybridge1_001820 [O-][N+](=O)c1cccc2cnccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K17 compound treatment 650460.0 -364000.0 -1.78 685170.0 -264000.0 -1.57 640490.0 -309695.806451613 -1.77378038432291 -2.9597 -0.9984 1711963 Maybridge1_001821 Nc1ccc(Oc2ccc(Cl)cc2C3CCCCC3)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K18 compound treatment 939160.0 -75800.0 -0.37 959230.0 9750.0 0.06 875870.0 -74315.806451613 -0.42564321822551 -0.4261 -0.7512 2070538 Maybridge1_001822 CCOC(CN(C(=O)c1ccc(C)cc1)c2ccc(F)cc2)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K19 compound treatment 868250.0 -147000.0 -0.72 832200.0 -117000.0 -0.7 768990.0 -181195.806451613 -1.03779760820125 -1.4157 -0.9822 2070539 Maybridge1_001823 Cc1ccc(OCc2c(Cl)cccc2Cl)c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K20 compound treatment 1024010.0 9050.0 0.04 978240.0 28800.0 0.17 896850.0 -53335.806451613 -0.305480427229149 -0.0521 -0.1476 1513140 Maybridge1_001824 COC(=O)c1ccncc1C(=O)Nc2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K21 compound treatment 839970.0 -175000.0 -0.85 789850.0 -160000.0 -0.95 729130.0 -221055.806451613 -1.2660954561095 -1.7726 -0.9856 2070540 Maybridge1_001825 Cc1nn(nc1C(=O)Oc2ccc(C)nc2[N+](=O)[O-])c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K22 compound treatment 751430.0 -264000.0 -1.29 693390.0 -256000.0 -1.52 632160.0 -318025.806451613 -1.82149039619134 -2.6742 -0.9901 2070541 Maybridge1_001826 Clc1ccc(cc1)S(=O)(=O)Oc2ccc(/C=C/3\NC(=O)NC3=O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K23 mock treatment 988970.0 -26000.0 -0.13 929220.0 -20300.0 -0.12 972890.0 22704.193548387 0.130038096477396 -0.0678 -0.3109 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 K24 mock treatment 999760.0 -15200.0 -0.07 970950.0 21500.0 0.13 921860.0 -28325.806451613 -0.162235841775431 -0.0628 -0.2863 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L01 compound treatment 1062000.0 47000.0 0.23 1009760.0 60300.0 0.36 1122290.0 172104.193548387 0.985725464201723 0.9088 0.8463 1323730 Maybridge1_001827 Clc1ccc(Cl)c(c1)S(=O)(=O)N2CCC(CC2)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L02 compound treatment 1035760.0 20800.0 0.1 935220.0 -14300.0 -0.08 862260.0 -87925.806451613 -0.503594390077773 -0.281 -0.5397 2070542 Maybridge1_001828 CCOC(=O)c1cnn(c1C)c2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L03 compound treatment 808730.0 -206000.0 -1.01 839590.0 -110000.0 -0.65 671010.0 -279175.806451613 -1.59897731562849 -1.8822 -0.9412 2070543 Maybridge1_001829 CC/1=NN(C(=O)\C1=C\c2ccc(O)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L04 compound treatment 1035790.0 20800.0 0.1 999380.0 49900.0 0.3 950630.0 444.193548387033 0.00254411518192389 0.2316 0.7381 1356933 Maybridge1_001830 Cc1ccc(Sc2ncccc2C(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L05 compound treatment 1200640.0 186000.0 0.91 716870.0 -233000.0 -1.38 970900.0 20714.193548387 0.118640386559247 -0.2063 -0.1244 2070544 Maybridge1_001831 CC/1=NN(C(=O)\C1=C\c2ccc(OCc3ccccc3)cc2)c4cccc(Cl)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L06 compound treatment 992800.0 -22200.0 -0.11 881720.0 -67800.0 -0.4 574240.0 -375945.806451613 -2.1532267572261 -1.5383 -0.7014 1009523 Maybridge1_001832 Cc1cc(O)n2cnnc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L07 compound treatment 1135910.0 121000.0 0.59 1056270.0 107000.0 0.64 933130.0 -17055.806451613 -0.0976870021887302 0.6514 0.7462 1684089 Maybridge1_001833 COc1ccccc1NC(=S)NCC(C)(C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L08 compound treatment 1233720.0 219000.0 1.07 1146990.0 198000.0 1.17 855690.0 -94495.806451613 -0.541224015284927 0.9827 0.5857 1563767 Maybridge1_001834 NC(=O)c1cccnc1Sc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L09 compound treatment 539700.0 -475000.0 -2.32 540020.0 -409000.0 -2.43 528320.0 -421865.806451613 -2.4162332092067 -4.1414 -0.9998 2070545 Maybridge1_001835 CC(C)(C)c1nnc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L10 compound treatment 973020.0 -41900.0 -0.2 931380.0 -18100.0 -0.11 900870.0 -49315.806451613 -0.282455907696004 -0.3435 -0.9407 2070546 Maybridge1_001836 COC(=O)c1c(SC)nc([nH]c1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L11 compound treatment 675970.0 -339000.0 -1.66 674460.0 -275000.0 -1.64 603970.0 -346215.806451613 -1.98294840754442 -3.0453 -0.9959 2070547 Maybridge1_001837 Cc1ccc(Sc2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L12 compound treatment 897830.0 -117000.0 -0.57 896730.0 -52700.0 -0.31 981520.0 31334.193548387 0.179466356072181 -0.4079 -0.6026 2070548 Maybridge1_001838 Cc1ccc(SCc2cc(=O)[nH]c(=O)[nH]2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L13 compound treatment 1281820.0 267000.0 1.3 1262310.0 313000.0 1.86 980660.0 30474.193548387 0.174540712589966 1.9276 0.846 2070549 Maybridge1_001839 CSc1nc2ncc(C(=O)O)c(N)n2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L14 compound treatment 971440.0 -43500.0 -0.21 930520.0 -19000.0 -0.11 1151390.0 201204.193548387 1.15239549365807 0.4775 0.4056 1630711 Maybridge1_001840 Nc1[nH]nc2[nH]c(nc(=O)c12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L15 compound treatment 948130.0 -66800.0 -0.33 911160.0 -38300.0 -0.23 994080.0 43894.193548387 0.251403660882205 -0.1749 -0.3715 2070550 Maybridge1_001841 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2ccc(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L16 compound treatment 904260.0 -111000.0 -0.54 861010.0 -88500.0 -0.53 877790.0 -72395.806451613 -0.414646432776844 -0.8554 -0.9936 2070551 Maybridge1_001842 Cc1nn(C)c(=O)c2noc(/C=C/c3ccc(Cl)c(Cl)c3)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L17 compound treatment 963720.0 -51200.0 -0.25 845840.0 -104000.0 -0.62 869360.0 -80825.806451613 -0.462929193887394 -0.7676 -0.9472 1168720 Maybridge1_001843 Cc1cc(Oc2ccc(NS(=O)(=O)c3cccc4cccnc34)cn2)cc(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L18 compound treatment 906560.0 -108000.0 -0.53 840740.0 -109000.0 -0.65 840510.0 -109675.806451613 -0.628167350238443 -1.0418 -0.9964 2070552 Maybridge1_001844 Cc1cc(N/C=N/O)c2ccccc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L19 compound treatment 600390.0 -415000.0 -2.03 545360.0 -404000.0 -2.4 485920.0 -464265.806451613 -2.65907888786474 -4.0921 -0.994 1497053 Maybridge1_001845 CC(C)(C)c1ccc(COc2cccnc2N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L20 compound treatment 422500.0 -592000.0 -2.89 429940.0 -520000.0 -3.09 469350.0 -480835.806451613 -2.7539834372837 -5.0449 -0.9989 2070553 Maybridge1_001846 Cc1cc(O)n(n1)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L21 compound treatment 843490.0 -171000.0 -0.84 789470.0 -160000.0 -0.95 832740.0 -117445.806451613 -0.672669966351014 -1.4214 -0.9904 2070554 Maybridge1_001847 Cn1c(S)nnc1SCc2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L22 compound treatment 588330.0 -427000.0 -2.08 541570.0 -408000.0 -2.43 504960.0 -445225.806451613 -2.55002743216547 -4.0762 -0.9965 1428836 Maybridge1_001848 Cc1nc(cs1)c2ccc3NC(=O)CCc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L23 mock treatment 994720.0 -20200.0 -0.1 902500.0 -47000.0 -0.28 1030270.0 80084.193548387 0.458681611604718 0.0464 0.085 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 L24 mock treatment 1126630.0 112000.0 0.55 1078040.0 129000.0 0.76 941160.0 -9025.80645161297 -0.0516952380466529 0.7265 0.7724 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M01 compound treatment 518600.0 -496000.0 -2.43 481720.0 -468000.0 -2.78 483040.0 -467145.806451613 -2.67557406603774 -4.5508 -0.9984 2070555 Maybridge1_001849 Clc1ccc(cc1)C(=O)CC(=S)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M02 compound treatment 1160160.0 145000.0 0.71 1153760.0 204000.0 1.21 988030.0 37844.193548387 0.216752331734065 1.2361 0.8684 2070556 Maybridge1_001850 CC(C)(C)c1cc(OC(=O)c2ccc(Cl)cc2Cl)c(cc1OC(=O)c3ccc(Cl)cc3Cl)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M03 compound treatment 929380.0 -85600.0 -0.42 920050.0 -29400.0 -0.17 1049120.0 98934.193548387 0.566644843743965 -0.0153 -0.0211 2070557 Maybridge1_001851 Cc1ccc(=O)n(Cc2ccc(Cl)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M04 compound treatment 1073720.0 58800.0 0.29 975960.0 26500.0 0.16 979730.0 29544.193548387 0.169214144638269 0.3544 0.9614 2070558 Maybridge1_001852 Nc1c(C#N)cnn1c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M05 compound treatment 1170180.0 155000.0 0.76 964320.0 14800.0 0.09 1000420.0 50234.193548387 0.287715962832488 0.6549 0.8027 1397157 Maybridge1_001853 Fc1cccc(Cl)c1COc2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M06 compound treatment 352830.0 -662000.0 -3.24 211200.0 -738000.0 -4.39 39390.0 -910795.806451613 -5.21657607869435 -7.4142 -0.9825 1212300 Maybridge1_001854 COc1ccc(Oc2c(Cl)cnn(c3ccc(Cl)cc3)c2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M07 compound treatment 1088570.0 73600.0 0.36 915940.0 -33500.0 -0.2 923600.0 -26585.806451613 -0.152270004962578 0.0046 0.0105 1271392 Maybridge1_001855 O=C(Nc1ccccc1)Oc2ccc(CC#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M08 compound treatment 1108830.0 93900.0 0.46 1011790.0 62300.0 0.37 893220.0 -56965.806451613 -0.326271224718033 0.2904 0.4309 2070559 Maybridge1_001856 [O-][N+](=O)c1cc(Cl)c(cc1Oc2ccc(Cl)cc2)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M09 compound treatment 1175040.0 160000.0 0.78 1088930.0 139000.0 0.83 996670.0 46484.193548387 0.266237866253062 1.084 0.9261 2070560 Maybridge1_001857 CC(C)Oc1ccccc1Oc2ccc(cn2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M10 compound treatment 544290.0 -471000.0 -2.3 646660.0 -303000.0 -1.8 636750.0 -313435.806451613 -1.79520120597813 -3.4038 -0.9928 1239145 Maybridge1_001858 Nc1cc(Cl)c(cc1Oc2ccc(Cl)cc2)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M11 compound treatment 684660.0 -330000.0 -1.61 720570.0 -229000.0 -1.36 846740.0 -103445.806451613 -0.59248507245449 -2.0597 -0.9393 2070561 Maybridge1_001859 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M12 compound treatment 1161770.0 147000.0 0.72 1041600.0 92100.0 0.55 894560.0 -55625.806451613 -0.318596384873652 0.5465 0.5709 1175941 Maybridge1_001860 COc1c(Cl)cc(Cl)c(OC)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M13 compound treatment 802890.0 -212000.0 -1.04 837470.0 -112000.0 -0.67 780000.0 -170185.806451613 -0.974737916644059 -1.5455 -0.9839 2070562 Maybridge1_001861 Cc1cccc(Oc2ccc(cn2)[N+](=O)[O-])c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M14 compound treatment 877880.0 -137000.0 -0.67 794520.0 -155000.0 -0.92 838350.0 -111835.806451613 -0.640538733868193 -1.2885 -0.9859 2070563 Maybridge1_001862 CSc1ncccc1C(=O)c2c(C)nn(c2O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M15 compound treatment 975430.0 -39500.0 -0.19 852200.0 -97300.0 -0.58 883040.0 -67145.806451613 -0.384577097565648 -0.6675 -0.9258 2070564 Maybridge1_001863 Nc1ccc(Oc2cccnc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M16 compound treatment 1136320.0 121000.0 0.59 1030350.0 80900.0 0.48 926570.0 -23615.806451613 -0.135259352471673 0.5419 0.6989 1616749 Maybridge1_001864 CCOC(=O)c1c[nH]c2c(F)ccc(F)c2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M17 compound treatment 987940.0 -27000.0 -0.13 933370.0 -16100.0 -0.1 973550.0 23364.193548387 0.133818241475375 -0.0543 -0.2572 2070565 Maybridge1_001865 CCOC(=O)/C(=C/Nc1ccc(Oc2cccnc2)nc1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M18 compound treatment 992160.0 -22800.0 -0.11 867170.0 -82300.0 -0.49 840010.0 -110175.806451613 -0.631031096449033 -0.7112 -0.882 2070566 Maybridge1_001866 CCOC(CN(C(=O)c1ccc(cc1)[N+](=O)[O-])c2ccc(F)cc2)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M19 compound treatment 894240.0 -121000.0 -0.59 808080.0 -141000.0 -0.84 868210.0 -81975.806451613 -0.469515810171751 -1.0971 -0.9714 2070567 Maybridge1_001867 Cc1ccc(OCc2c(F)cccc2Cl)c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M20 compound treatment 810790.0 -204000.0 -1.0 879460.0 -70000.0 -0.42 867220.0 -82965.806451613 -0.475186027668719 -1.0907 -0.9237 2070568 Maybridge1_001868 CN(C)/C=N/c1ncc(cc1Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M21 compound treatment 887860.0 -127000.0 -0.62 933160.0 -16300.0 -0.1 913370.0 -36815.806451613 -0.210862252431252 -0.5363 -0.809 2070569 Maybridge1_001869 Cc1ccc(OS(=O)(=O)c2ccc(F)cc2)c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M22 compound treatment 977280.0 -37700.0 -0.18 893650.0 -55800.0 -0.33 894580.0 -55605.806451613 -0.318481835025228 -0.4818 -0.9724 2070570 Maybridge1_001870 Clc1ccc(cc1)C(=O)Oc2ccc(/C=C/3\NC(=O)NC3=O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M23 mock treatment 944730.0 -70200.0 -0.34 828660.0 -121000.0 -0.72 982100.0 31914.193548387 0.182788301676466 -0.5074 -0.6211 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 M24 mock treatment 1008350.0 -6610.0 -0.03 1040170.0 90700.0 0.54 973690.0 23504.193548387 0.13462009041434 0.3705 0.6653 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N01 compound treatment 1173400.0 158000.0 0.77 1028240.0 78800.0 0.47 1013350.0 63164.193548387 0.361772439838348 0.9262 0.9505 1425744 Maybridge1_001871 Cc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N02 compound treatment 448590.0 -566000.0 -2.77 482880.0 -467000.0 -2.77 480820.0 -469365.806451613 -2.68828909921276 -4.7517 -0.9999 2070571 Maybridge1_001872 Fc1ccc(cc1F)C(=O)CSC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N03 compound treatment 965370.0 -49600.0 -0.24 927240.0 -22200.0 -0.13 911380.0 -38805.806451613 -0.2222599623494 -0.3446 -0.9723 2070572 Maybridge1_001873 CC/1=NN(C(=O)\C1=C\c2ccc(O)cc2)c3cccc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N04 compound treatment 1193120.0 178000.0 0.87 1159590.0 210000.0 1.25 992280.0 42094.193548387 0.241094174524081 1.3631 0.8842 1917780 Maybridge1_001874 CCOC(=O)CNC(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N05 compound treatment 1221300.0 206000.0 1.01 1188730.0 239000.0 1.42 961810.0 11624.193548387 0.0665774804507189 1.4419 0.8263 1067559 Maybridge1_001875 CCOc1ccc(N=c2ssc(SC)c2c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N06 compound treatment 1070970.0 56000.0 0.27 998440.0 49000.0 0.29 917320.0 -32865.806451613 -0.18823865736759 0.2174 0.4922 2070573 Maybridge1_001876 CCOC(=O)CNC(=O)c1ccccc1NCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N07 compound treatment 895950.0 -119000.0 -0.58 794080.0 -155000.0 -0.92 675490.0 -274695.806451613 -1.57331814958161 -1.7776 -0.9282 2070574 Maybridge1_001877 Fc1ccc(NC(=O)CSc2ccc(Cl)cc2)c(F)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N08 compound treatment 1191240.0 176000.0 0.86 1012030.0 62600.0 0.37 1119650.0 169464.193548387 0.970604884209807 1.2724 0.9426 1313213 Maybridge1_001878 Cc1ccc(Sc2ncccc2C(=O)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N09 compound treatment 964260.0 -50700.0 -0.25 973600.0 24100.0 0.14 874460.0 -75725.806451613 -0.433718982539374 -0.3106 -0.5977 1213969 Maybridge1_001879 COC(=O)COc1c(C)cc(cc1C)c2nn(C)c(=O)c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N10 compound treatment 1042770.0 27800.0 0.14 942720.0 -6760.0 -0.04 936730.0 -13455.806451613 -0.0770680294724813 0.0108 0.0667 2070575 Maybridge1_001880 CSc1nc([nH]c(=O)c1C#N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N11 compound treatment 198300.0 -817000.0 -3.99 192170.0 -757000.0 -4.5 211690.0 -738495.806451613 -4.229729134525 -7.3457 -0.9988 2070576 Maybridge1_001881 FC(F)(F)Sc1ccc(NC(=O)Nc2ccc(Sc3ccc(Cl)cc3)nc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N12 compound treatment 1063920.0 49000.0 0.24 1030720.0 81200.0 0.48 936850.0 -13335.806451613 -0.0763807303819397 0.3729 0.6849 2070577 Maybridge1_001882 Clc1ccc(SCc2cc(=O)[nH]c(=O)[nH]2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N13 compound treatment 1086260.0 71300.0 0.35 1029560.0 80100.0 0.48 1034520.0 84334.193548387 0.483023454394734 0.7549 0.9901 2070578 Maybridge1_001883 CSc1nc2nccc(N)n2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N14 compound treatment 985120.0 -29800.0 -0.15 871450.0 -78000.0 -0.46 1020670.0 70484.193548387 0.403697684361387 -0.119 -0.1882 2070579 Maybridge1_001884 OCCSc1ccc(Cl)cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N15 compound treatment 884550.0 -130000.0 -0.64 838480.0 -111000.0 -0.66 881140.0 -69045.806451613 -0.39545933316589 -0.9773 -0.9782 2070580 Maybridge1_001885 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(F)cc2NS(=O)(=O)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N16 compound treatment 775840.0 -239000.0 -1.17 751520.0 -198000.0 -1.18 803200.0 -146985.806451613 -0.841860092472678 -1.8402 -0.9894 1510809 Maybridge1_001886 CCOC(=O)C1=C(N)CC(=C(N)C1)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N17 compound treatment 220350.0 -795000.0 -3.88 302840.0 -647000.0 -3.85 223960.0 -726225.806451613 -4.15945280251712 -6.863 -0.9994 2070581 Maybridge1_001887 COc1cccc(c1)C(=O)N/N=C(\C)/c2ccccc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N18 compound treatment 963080.0 -51900.0 -0.25 878100.0 -71400.0 -0.42 961190.0 11004.193548387 0.0630264351495871 -0.355 -0.7123 2070582 Maybridge1_001888 CC(=O)c1cc(C#N)c(=O)[nH]c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N19 compound treatment 646320.0 -369000.0 -1.8 665120.0 -284000.0 -1.69 653540.0 -296645.806451613 -1.69903660822651 -2.9971 -0.9996 1163521 Maybridge1_001889 Cc1cccc(COc2cccnc2N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N20 compound treatment 957610.0 -57300.0 -0.28 835520.0 -114000.0 -0.68 775950.0 -174235.806451613 -0.997934260949839 -1.1292 -0.9118 2070583 Maybridge1_001890 Cc1cc(O)n(n1)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N21 compound treatment 989240.0 -25700.0 -0.13 908210.0 -41300.0 -0.25 891520.0 -58665.806451613 -0.33600796183404 -0.4082 -0.9392 2070584 Maybridge1_001891 Cn1c(S)nnc1SCc2c(F)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N22 compound treatment 961140.0 -53800.0 -0.26 949990.0 512.0 0.0 908220.0 -41965.806451613 -0.24035883840033 -0.2888 -0.8107 2070585 Maybridge1_001892 COc1cccc(CC(=O)N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N23 mock treatment 1080410.0 65500.0 0.32 965620.0 16100.0 0.1 1071720.0 121534.193548387 0.696086172462638 0.6419 0.8315 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 N24 mock treatment 879840.0 -135000.0 -0.66 906560.0 -42900.0 -0.26 934610.0 -15575.806451613 -0.0892103134053834 -0.58 -0.813 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O01 compound treatment 1025320.0 10400.0 0.05 1066950.0 117000.0 0.7 932880.0 -17305.806451613 -0.0991188752940252 0.3753 0.5306 2070586 Maybridge1_001893 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O02 compound treatment 1067000.0 52000.0 0.25 1107450.0 158000.0 0.94 1031800.0 81614.193548387 0.467444675009123 0.959 0.8883 2070587 Maybridge1_001894 CC(C)(C)c1cc(OS(=O)(=O)c2ccc(Cl)cc2)c(cc1OS(=O)(=O)c3ccc(Cl)cc3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O03 compound treatment 1093000.0 78000.0 0.38 1100860.0 151000.0 0.9 901320.0 -48865.806451613 -0.279878536106473 0.5783 0.5687 2070588 Maybridge1_001895 Cc1ccc(=O)n(Cc2ccc(Cl)c(Cl)c2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O04 compound treatment 1207050.0 192000.0 0.94 984010.0 34500.0 0.21 1100800.0 150614.193548387 0.862641652070559 1.1585 0.8972 2070589 Maybridge1_001896 Nc1nn(cc1C#N)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O05 compound treatment 1017640.0 2680.0 0.01 948040.0 -1440.0 -0.01 908480.0 -41705.806451613 -0.238869690370823 -0.1353 -0.5651 1152248 Maybridge1_001897 Clc1ccc(COc2ccc(CC#N)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O06 compound treatment 1234880.0 220000.0 1.07 1121690.0 172000.0 1.02 1161830.0 211644.193548387 1.21219051453519 1.9115 0.9974 2070590 Maybridge1_001898 CC(C)(C)c1cc(Cl)c(OS(=O)(=O)c2ccc(Cl)cc2)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O07 compound treatment 1185130.0 170000.0 0.83 1147440.0 198000.0 1.18 1043360.0 93174.193548387 0.533654487397967 1.4678 0.9551 2070591 Maybridge1_001899 FC(F)(F)c1ccc(/C=C(\C#N)/c2ccc(OCc3ccc(Cl)cc3)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O08 compound treatment 905490.0 -109000.0 -0.53 907880.0 -41600.0 -0.25 968280.0 18094.193548387 0.103634356415755 -0.3918 -0.6548 2070592 Maybridge1_001900 [O-][N+](=O)c1cc(Cl)c(cc1Sc2ccc(Cl)cc2)n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O09 compound treatment 873190.0 -142000.0 -0.69 870790.0 -78700.0 -0.47 803270.0 -146915.806451613 -0.841459168003195 -1.1559 -0.9745 2070593 Maybridge1_001901 C/C(=N/O)/c1ccn(c1)S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O10 compound treatment 1110460.0 95500.0 0.47 921440.0 -28000.0 -0.17 952220.0 2034.19354838703 0.0116508281316005 0.1799 0.3629 2070594 Maybridge1_001902 COc1ccc(Cl)c(OC)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O11 compound treatment 821470.0 -193000.0 -0.95 827300.0 -122000.0 -0.73 851680.0 -98505.806451613 -0.56419125989386 -1.291 -0.9787 2070595 Maybridge1_001903 Cc1ccc(Sc2ccc(cn2)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O12 compound treatment 1072210.0 57300.0 0.28 1033440.0 84000.0 0.5 1084530.0 134344.193548387 0.769455350377957 0.894 0.9323 2070596 Maybridge1_001904 COc1c(Br)cc([N+](=O)[O-])c(OC)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O13 compound treatment 732590.0 -282000.0 -1.38 719070.0 -230000.0 -1.37 735100.0 -215085.806451613 -1.23190232635505 -2.2988 -0.9987 2070597 Maybridge1_001905 [O-][N+](=O)c1ccc(Oc2cccc(Cl)c2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O14 compound treatment 962210.0 -52700.0 -0.26 921330.0 -28100.0 -0.17 943730.0 -6455.80645161297 -0.0369755825242197 -0.2668 -0.8619 2070598 Maybridge1_001906 CN(C)/C=C(/Sc1nnc(s1)n2cccc2)\C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O15 compound treatment 795220.0 -220000.0 -1.07 738170.0 -211000.0 -1.26 780190.0 -169995.806451613 -0.973649693084035 -1.9075 -0.9944 2070599 Maybridge1_001907 Nc1ccc(Oc2ccc(Br)cc2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O16 compound treatment 1020000.0 5040.0 0.02 983860.0 34400.0 0.2 836660.0 -113525.806451613 -0.650218196059987 -0.2431 -0.3565 2070600 Maybridge1_001908 Clc1ccc(cc1Cl)c2csc(=S)n2Nc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O17 compound treatment 963560.0 -51400.0 -0.25 893940.0 -55500.0 -0.33 962880.0 12694.193548387 0.0727058973413817 -0.2937 -0.6972 2070601 Maybridge1_001909 COC(=O)c1ccc(Cl)cc1NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O18 compound treatment 941960.0 -73000.0 -0.36 975890.0 26400.0 0.16 959200.0 9014.19354838703 0.0516287252314385 -0.0854 -0.2173 2070602 Maybridge1_001910 Fc1ccc(NC(=O)CC#N)c(F)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O19 compound treatment 717280.0 -298000.0 -1.45 686350.0 -263000.0 -1.56 808680.0 -141505.806451613 -0.81047343400461 -2.211 -0.9677 2070603 Maybridge1_001911 Cc1ccc(COc2ccc(C)nc2[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O20 compound treatment 869300.0 -146000.0 -0.71 866880.0 -82600.0 -0.49 786880.0 -163305.806451613 -0.935332768786339 -1.2345 -0.9691 2070604 Maybridge1_001912 FC(F)(F)c1cnc(NCc2cccnc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O21 compound treatment 752980.0 -262000.0 -1.28 726350.0 -223000.0 -1.33 723450.0 -226735.806451613 -1.2986276130618 -2.2548 -0.9999 2070605 Maybridge1_001913 Cc1ccc(OS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(n1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O22 compound treatment 940170.0 -74800.0 -0.37 885540.0 -63900.0 -0.38 852160.0 -98025.806451613 -0.561442063531694 -0.7546 -0.9797 2070606 Maybridge1_001914 [O-][N+](=O)c1cccnc1Oc2ccccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O23 mock treatment 1117440.0 102000.0 0.5 1101120.0 152000.0 0.9 1061440.0 111254.193548387 0.637207550372905 1.1776 0.9713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 O24 mock treatment 966650.0 -48300.0 -0.24 914510.0 -35000.0 -0.21 858100.0 -92085.806451613 -0.527420758549883 -0.5608 -0.9133 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P01 compound treatment 960760.0 -54200.0 -0.26 925380.0 -24100.0 -0.14 979480.0 29294.193548387 0.167782271532974 -0.1387 -0.4025 1019665 Maybridge1_001915 O=S(=O)(NCc1ccccc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P02 compound treatment 1139400.0 124000.0 0.61 1106740.0 157000.0 0.94 956050.0 5864.19354838703 0.0335871241047207 0.9103 0.8158 1595756 Maybridge1_001916 CC(C)(C)c1ccc(Oc2ccc(NC(=O)Cc3cccs3)cn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P03 compound treatment 1100490.0 85500.0 0.42 1009210.0 59700.0 0.36 993220.0 43034.193548387 0.24647801739999 0.5886 0.979 2070607 Maybridge1_001917 COc1ccc(/C=C/2\C(=NN(C2=O)c3cccc(Cl)c3)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P04 compound treatment 1129800.0 115000.0 0.56 1042570.0 93100.0 0.55 985570.0 35384.193548387 0.202662700377961 0.7606 0.9345 2070608 Maybridge1_001918 CCOC(=O)CNC(=O)c1cccnc1SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P05 compound treatment 1125880.0 111000.0 0.54 1088610.0 139000.0 0.83 969170.0 18984.193548387 0.108731824670605 0.8533 0.8576 1552765 Maybridge1_001919 COc1ccccc1NC(=S)N2CC(C)(C)C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P06 compound treatment 1147790.0 133000.0 0.65 1130970.0 181000.0 1.08 975790.0 25604.193548387 0.146647824498819 1.0825 0.8538 2070609 Maybridge1_001920 CCOC(=O)CNC(=O)c1ccccc1N(CC=C)C(=O)c2cccc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P07 compound treatment 1029840.0 14900.0 0.07 1036990.0 87500.0 0.52 1075400.0 125214.193548387 0.717163344572581 0.7565 0.8509 2070610 Maybridge1_001921 CCOC(=O)N1CCCN=C1NNc2cc(F)ccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P08 compound treatment 1186200.0 171000.0 0.84 1101730.0 152000.0 0.91 956200.0 6014.19354838703 0.0344462479678978 1.0257 0.8317 2070611 Maybridge1_001922 FC(F)(F)C1=NN2C(=NC(=O)CC2=N)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P09 compound treatment 1031400.0 16400.0 0.08 973440.0 24000.0 0.14 1020390.0 70204.193548387 0.402093986483457 0.3608 0.8311 1305583 Maybridge1_001923 Cc1cc(cc(C)c1OC(=O)Nc2ccccc2)c3nn(C)c(=O)c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P10 compound treatment 810720.0 -204000.0 -1.0 782080.0 -167000.0 -1.0 751710.0 -198475.806451613 -1.13676867723925 -1.8072 -0.998 2070612 Maybridge1_001924 CCOC(=O)c1nn(c2ccc(cc2)C(C)(C)C)c(=N)c(C#N)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P11 compound treatment 594250.0 -421000.0 -2.06 658570.0 -291000.0 -1.73 600960.0 -349225.806451613 -2.00018815973217 -3.3403 -0.9973 2070613 Maybridge1_001925 Cc1ccc(Sc2ccc(NC(=O)Nc3ccc(SC(F)(F)F)cc3)cn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P12 compound treatment 1099310.0 84400.0 0.41 1008170.0 58700.0 0.35 992970.0 42784.193548387 0.245046144294695 0.5809 0.9796 2070614 Maybridge1_001926 CN(C)/C=N/c1ncccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P13 compound treatment 1093560.0 78600.0 0.38 1121930.0 172000.0 1.03 1017760.0 67574.193548387 0.387030681415753 1.0372 0.8931 2070615 Maybridge1_001927 Nc1nnc(SCC(=O)Nc2ccc(F)c(F)c2F)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P14 compound treatment 107420.0 -908000.0 -4.43 116700.0 -833000.0 -4.95 120650.0 -829535.806451613 -4.75116004454925 -8.1622 -0.999 2070616 Maybridge1_001928 Clc1ccc(nc1)S(=O)(=O)CCOC(=O)c2cccc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P15 compound treatment 1028700.0 13700.0 0.07 1026020.0 76500.0 0.46 905640.0 -44545.806451613 -0.255135768846975 0.1542 0.2932 2070617 Maybridge1_001929 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P16 compound treatment 961690.0 -53300.0 -0.26 942980.0 -6500.0 -0.04 1027370.0 77184.193548387 0.442071883583295 0.0827 0.1607 2070618 Maybridge1_001930 Nc1nc(cs1)c2ccc(Br)s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P17 compound treatment 817970.0 -197000.0 -0.96 826600.0 -123000.0 -0.73 833510.0 -116675.806451613 -0.668259797186705 -1.3634 -0.9873 2070619 Maybridge1_001931 OC(=O)CC/C(=N\Nc1ccc(cc1)[N+](=O)[O-])/c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P18 compound treatment 976960.0 -38000.0 -0.19 968580.0 19100.0 0.11 834630.0 -115555.806451613 -0.661845005674983 -0.4237 -0.6082 2070620 Maybridge1_001932 NC(=N)NCCS(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P19 compound treatment 639790.0 -375000.0 -1.83 639460.0 -310000.0 -1.84 636200.0 -313985.806451613 -1.79835132680978 -3.1609 -0.9999 2070621 Maybridge1_001933 CN(C)/C=N/c1ncccc1OCc2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P20 compound treatment 936420.0 -78500.0 -0.38 944000.0 -5480.0 -0.03 806970.0 -143215.806451613 -0.820267446044828 -0.7139 -0.7879 1950715 Maybridge1_001934 Cc1cc(O)n(n1)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P21 compound treatment 915440.0 -99500.0 -0.49 848520.0 -101000.0 -0.6 896090.0 -54095.806451613 -0.309833321469246 -0.8062 -0.9686 2070622 Maybridge1_001935 Cn1c(S)nnc1SCc2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P22 compound treatment 1028840.0 13900.0 0.07 980800.0 31300.0 0.19 993210.0 43024.193548387 0.246420742475778 0.289 0.9137 2070623 Maybridge1_001936 COc1ccc(C(=O)O)c(Cl)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P23 mock treatment 1007450.0 -7510.0 -0.04 1002240.0 52800.0 0.31 1196490.0 246304.193548387 1.4107054018533 0.9744 0.6741 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.546 P24 mock treatment 906310.0 -109000.0 -0.53 967380.0 17900.0 0.11 926470.0 -23715.806451613 -0.135832101713791 -0.3234 -0.5795 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A01 compound treatment 914360.0 -167000.0 -0.81 890400.0 -145000.0 -0.86 901410.0 -137437.41935484 -0.787171777741415 -1.4219 -0.9993 1585994 Maybridge1_001937 COc1cccc(CC(=O)NN)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A02 compound treatment 946160.0 -135000.0 -0.66 926560.0 -109000.0 -0.65 881130.0 -157717.41935484 -0.90332532404295 -1.2751 -0.9873 2070624 Maybridge1_001938 CCCCCc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A03 compound treatment 950970.0 -130000.0 -0.64 887810.0 -147000.0 -0.88 865030.0 -173817.41935484 -0.995537952023952 -1.4478 -0.9843 1506162 Maybridge1_001939 CCOC(=O)C1=C(O)C(=O)N(C1)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A04 compound treatment 976160.0 -105000.0 -0.51 858170.0 -177000.0 -1.05 865290.0 -173557.41935484 -0.994048803994445 -1.4776 -0.9619 2070625 Maybridge1_001940 CCCCCCN(CCCCCC)c1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A05 compound treatment 989540.0 -91400.0 -0.45 940210.0 -95100.0 -0.57 906420.0 -132427.41935484 -0.758477040711302 -1.0222 -0.9771 1271035 Maybridge1_001941 NC(=O)C1=C(O)C(=O)N(C1)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A06 compound treatment 853010.0 -228000.0 -1.11 707590.0 -328000.0 -1.95 811300.0 -227547.41935484 -1.30327611981397 -2.5205 -0.9711 2070626 Maybridge1_001942 C/C(=N/O)/c1cc(cc2c1CCC2(C)C)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A07 compound treatment 904710.0 -176000.0 -0.86 924220.0 -111000.0 -0.66 876320.0 -162527.41935484 -0.930874562588827 -1.4159 -0.9903 1014249 Maybridge1_001943 CCOC(=O)c1[nH]c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A08 compound treatment 891910.0 -189000.0 -0.92 901300.0 -134000.0 -0.8 790940.0 -247907.41935484 -1.4198878655092 -1.8131 -0.9686 2070627 Maybridge1_001944 COc1cc(CC/C(=N/O)/C)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A09 compound treatment 952580.0 -128000.0 -0.63 848280.0 -187000.0 -1.11 924740.0 -114107.41935484 -0.65354937955528 -1.3815 -0.9632 2070628 Maybridge1_001945 COC(=O)c1cc2ccccc2cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A10 compound treatment 952120.0 -129000.0 -0.63 947230.0 -88000.0 -0.52 940800.0 -98047.4193548399 -0.561565851271126 -0.99 -0.9971 1168073 Maybridge1_001946 CCCc1c2CCCCc2cc3c(=O)cc(oc13)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A11 compound treatment 871110.0 -210000.0 -1.03 844170.0 -191000.0 -1.14 883090.0 -155757.41935484 -0.892099438897437 -1.7632 -0.9952 2070629 Maybridge1_001947 CC(=O)c1ccc(OCc2ccc(cc2)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A12 compound treatment 1052380.0 -28600.0 -0.14 875410.0 -160000.0 -0.95 902880.0 -135967.41935484 -0.77875236388228 -1.0791 -0.8725 1280207 Maybridge1_001948 CCOC(=O)c1cc(=O)c2ccc(OCC=C)cc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A13 compound treatment 1009340.0 -71600.0 -0.35 878970.0 -156000.0 -0.93 865630.0 -173217.41935484 -0.992101456571244 -1.3115 -0.9342 2070630 Maybridge1_001949 O=C1CCCc2[nH]c(=O)c(C#N)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A14 compound treatment 646570.0 -434000.0 -2.12 701620.0 -334000.0 -1.98 633020.0 -405827.41935484 -2.32437346866198 -3.7129 -0.9979 2070631 Maybridge1_001950 CCCCCCc1cc2c(C)cc(=O)oc2cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A15 compound treatment 460480.0 -620000.0 -3.03 448370.0 -587000.0 -3.49 454340.0 -584507.41935484 -3.34776181447846 -5.6981 -0.9983 1026728 Maybridge1_001951 c1coc(c1)c2nc3ccccc3nc2c4ccco4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A16 compound treatment 1036700.0 -44300.0 -0.22 872960.0 -162000.0 -0.97 835410.0 -203437.41935484 -1.16518627753931 -1.3549 -0.8865 2070632 Maybridge1_001952 CCCc1cc([N+](=O)[O-])c(O)c2c(=O)cc(oc12)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A17 compound treatment 1044270.0 -36700.0 -0.18 862880.0 -172000.0 -1.03 871200.0 -167647.41935484 -0.96019932378527 -1.2498 -0.8826 1449566 Maybridge1_001953 COC(=O)CSc1cc(C)nc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A18 compound treatment 870400.0 -211000.0 -1.03 742120.0 -293000.0 -1.74 788060.0 -250787.41935484 -1.43638304368219 -2.4298 -0.9789 1555484 Maybridge1_001954 Brc1ccc(OCc2ccccc2)c(OCc3ccccc3)c1CCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A19 compound treatment 955450.0 -126000.0 -0.61 942150.0 -93100.0 -0.55 913820.0 -125027.41935484 -0.716093596794569 -1.0873 -0.9943 2070633 Maybridge1_001955 CCn1cc(nc1C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A20 compound treatment 903740.0 -177000.0 -0.87 829830.0 -205000.0 -1.22 890420.0 -148427.41935484 -0.850116919450186 -1.6961 -0.985 2070634 Maybridge1_001956 CC(=O)Nc1ccc(CC=C)c(O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A21 compound treatment 868000.0 -213000.0 -1.04 872490.0 -163000.0 -0.97 915000.0 -123847.41935484 -0.709335155737576 -1.5692 -0.9879 2070635 Maybridge1_001957 Cn1c2CCCC(=O)c2c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A22 compound treatment 834130.0 -247000.0 -1.21 777530.0 -258000.0 -1.53 785710.0 -253137.41935484 -1.44984265087197 -2.4183 -0.9951 1190426 Maybridge1_001958 CCCc1ccc(SC(=O)N(C)C)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A23 mock treatment 954890.0 -126000.0 -0.62 905810.0 -129000.0 -0.77 885410.0 -153437.41935484 -0.878811656480299 -1.3075 -0.99 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 A24 mock treatment 917920.0 -163000.0 -0.8 873330.0 -162000.0 -0.96 903090.0 -135757.41935484 -0.777549590473832 -1.4649 -0.9952 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B01 compound treatment 1031040.0 -49900.0 -0.24 1018400.0 -16900.0 -0.1 1056480.0 17632.5806451601 0.100990472011003 -0.1405 -0.4974 2070636 Maybridge1_001959 CCCCCCc1ccc(cc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B02 compound treatment 1037440.0 -43500.0 -0.21 1027870.0 -7410.0 -0.04 950890.0 -87957.4193548399 -0.503775452741417 -0.4391 -0.8004 1913687 Maybridge1_001960 COC(=O)CCC(=O)Nc1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B03 compound treatment 949030.0 -132000.0 -0.64 834490.0 -201000.0 -1.19 858720.0 -180127.41935484 -1.0316784292016 -1.6572 -0.9722 2070637 Maybridge1_001961 [O-][N+](=O)c1ccc(Sc2ccccc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B04 compound treatment 859330.0 -222000.0 -1.08 909170.0 -126000.0 -0.75 831590.0 -207257.41935484 -1.18706529858822 -1.7435 -0.9833 1478461 Maybridge1_001962 O=C1Cc2ccccc2C(N1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B05 compound treatment 215920.0 -865000.0 -4.23 262980.0 -772000.0 -4.59 47770.0 -991077.41935484 -5.67638840815771 -8.3689 -0.992 2070638 Maybridge1_001963 CC(C)(C)c1ccc(O)c(c1)/C(=N/O)/c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B06 compound treatment 1006150.0 -74800.0 -0.37 1045500.0 10200.0 0.06 916980.0 -121867.41935484 -0.697994720743639 -0.579 -0.7326 2070639 Maybridge1_001964 NC(=O)c1ccccc1OCCOc2ccccc2C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B07 compound treatment 759900.0 -321000.0 -1.57 694680.0 -341000.0 -2.03 773520.0 -265327.41935484 -1.51966078348616 -2.9524 -0.9912 2070640 Maybridge1_001965 Cc1ccc(C)n1c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B08 compound treatment 974120.0 -107000.0 -0.52 920040.0 -115000.0 -0.69 904640.0 -134207.41935484 -0.768671977221003 -1.1409 -0.9881 1214488 Maybridge1_001966 O=C1CCC(=O)N1CCc2cnc[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B09 compound treatment 981450.0 -99500.0 -0.49 959870.0 -75400.0 -0.45 914170.0 -124677.41935484 -0.714088974447155 -0.9519 -0.978 2070641 Maybridge1_001967 CCOC(=O)CC(=O)c1cccc(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B10 compound treatment 984640.0 -96300.0 -0.47 969700.0 -65600.0 -0.39 902730.0 -136117.41935484 -0.779611487745457 -0.947 -0.9559 2070642 Maybridge1_001968 OC(=O)CSc1nnc(S)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B11 compound treatment 996040.0 -84900.0 -0.41 894570.0 -141000.0 -0.84 875250.0 -163597.41935484 -0.93700297947949 -1.2637 -0.9552 1056525 Maybridge1_001969 COC(=O)c1cccc([N+](=O)[O-])c1c2c(cccc2[N+](=O)[O-])C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B12 compound treatment 954170.0 -127000.0 -0.62 1049280.0 14000.0 0.08 879160.0 -159687.41935484 -0.914608484112675 -0.8377 -0.7561 2070643 Maybridge1_001970 N#CC(C1CCC=CC1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B13 compound treatment 999250.0 -81700.0 -0.4 983460.0 -51800.0 -0.31 875330.0 -163517.41935484 -0.936544780085796 -0.9492 -0.8923 1287839 Maybridge1_001971 CN1C2CCC1CC(=NO)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B14 compound treatment 981730.0 -99200.0 -0.48 897170.0 -138000.0 -0.82 897090.0 -141757.41935484 -0.811914545000914 -1.2229 -0.9763 2070644 Maybridge1_001972 CC(=O)c1cc2OCCOc2cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B15 compound treatment 1095200.0 14200.0 0.07 956280.0 -79000.0 -0.47 971570.0 -67277.4193548399 -0.38533090947141 -0.4536 -0.7417 2070645 Maybridge1_001973 COc1ccc(NC(=O)C)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B16 compound treatment 1014620.0 -66400.0 -0.32 927490.0 -108000.0 -0.64 878490.0 -160357.41935484 -0.918445904034866 -1.0875 -0.9327 1275916 Maybridge1_001974 OC(=O)CCC(=O)c1ccc2OCCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B17 compound treatment 944440.0 -137000.0 -0.67 873440.0 -162000.0 -0.96 906590.0 -132257.41935484 -0.757503366999702 -1.3781 -0.9882 1040375 Maybridge1_001975 Ic1ccc-2c(c1)C(=O)c3ccccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B18 compound treatment 823200.0 -258000.0 -1.26 822260.0 -213000.0 -1.27 750740.0 -288107.41935484 -1.65013306084064 -2.4112 -0.9915 2070646 Maybridge1_001976 CC1Cc2cc(ccc2O1)/C(=N/O)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B19 compound treatment 741950.0 -339000.0 -1.66 717850.0 -317000.0 -1.89 708800.0 -330047.41935484 -1.89034409298494 -3.1375 -0.9982 1708515 Maybridge1_001977 CC(=CC1C(C(=O)OCN2C(=O)C3=C(CCCC3)C2=O)C1(C)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B20 compound treatment 856710.0 -224000.0 -1.1 779320.0 -256000.0 -1.52 779940.0 -258907.41935484 -1.48289028214218 -2.3675 -0.9902 2070647 Maybridge1_001978 C/C(=N\O)/C1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B21 compound treatment 1007450.0 -73500.0 -0.36 901940.0 -133000.0 -0.79 909360.0 -129487.41935484 -0.741638212993032 -1.0934 -0.9561 2070648 Maybridge1_001979 CCN(C(=O)C(Cc1ccccc1)C(=O)N(CC)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B22 compound treatment 975270.0 -106000.0 -0.52 920480.0 -115000.0 -0.68 915700.0 -123147.41935484 -0.70532591104275 -1.0995 -0.9913 1342250 Maybridge1_001980 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)NC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B23 mock treatment 919770.0 -161000.0 -0.79 956910.0 -78400.0 -0.47 1021120.0 -17727.4193548399 -0.10153366000193 -0.7824 -0.8497 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 B24 mock treatment 980820.0 -100000.0 -0.49 909720.0 -126000.0 -0.75 943370.0 -95477.4193548399 -0.546846195748693 -1.0293 -0.9832 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C01 compound treatment 1090650.0 9670.0 0.05 1009170.0 -26100.0 -0.16 911850.0 -126997.41935484 -0.727376756864294 -0.4823 -0.6472 2070649 Maybridge1_001981 COC(=O)c1ccc(OC)c(OC)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C02 compound treatment 1057080.0 -23900.0 -0.12 828090.0 -207000.0 -1.23 886260.0 -152587.41935484 -0.873943287922296 -1.2833 -0.847 1697962 Maybridge1_001982 CCCCc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C03 compound treatment 555310.0 -526000.0 -2.57 563620.0 -472000.0 -2.8 577130.0 -461717.41935484 -2.64448302008174 -4.6289 -0.9993 1018390 Maybridge1_001983 CCOC(=O)c1[nH]c(Cc2[nH]c(C(=O)OCC)c(C)c2CC)c(CC)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C04 compound treatment 913880.0 -167000.0 -0.82 973400.0 -61900.0 -0.37 929960.0 -108887.41935484 -0.62365186911672 -1.0439 -0.9566 1079253 Maybridge1_001984 CCCCCCCCc1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C05 compound treatment 953890.0 -127000.0 -0.62 961730.0 -73500.0 -0.44 994880.0 -43967.4193548399 -0.251823061133699 -0.7564 -0.9453 1087705 Maybridge1_001985 CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C06 compound treatment 1066930.0 -14000.0 -0.07 985000.0 -50300.0 -0.3 1007110.0 -31737.4193548399 -0.181775828822665 -0.3172 -0.8895 2070650 Maybridge1_001986 C/C(=N\OC(=O)c1cccs1)/c2cc(cc3c2CCC3(C)C)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C07 compound treatment 1123570.0 42600.0 0.21 1032600.0 -2680.0 -0.02 1153870.0 115022.58064516 0.658790958909746 0.4913 0.7109 2070651 Maybridge1_001987 CCN(CC)C(=O)c1[nH]c(C)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C08 compound treatment 994640.0 -86300.0 -0.42 945670.0 -89600.0 -0.53 960340.0 -78507.4193548399 -0.449650649361264 -0.8108 -0.995 1330494 Maybridge1_001988 CCn1c(cc(=O)c2cc(OC)ccc12)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C09 compound treatment 911520.0 -169000.0 -0.83 948540.0 -86700.0 -0.52 855140.0 -183707.41935484 -1.05218285206942 -1.3833 -0.9641 1210480 Maybridge1_001989 Cc1ccc(Oc2ncccc2N)c3CCCc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C10 compound treatment 725440.0 -356000.0 -1.74 705350.0 -330000.0 -1.96 818300.0 -220547.41935484 -1.2631836728657 -2.8649 -0.9848 1601940 Maybridge1_001990 CCCc1c(OCC=C)ccc2c(=O)cc(oc12)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C11 compound treatment 880480.0 -200000.0 -0.98 811430.0 -224000.0 -1.33 813240.0 -225607.41935484 -1.29216478451688 -2.0801 -0.9915 2070652 Maybridge1_001991 Cc1nc(cs1)c2cc(C#N)c(SCCNS(=O)(=O)c3cccc(c3)C(F)(F)F)nc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C12 compound treatment 926750.0 -154000.0 -0.75 956320.0 -79000.0 -0.47 912640.0 -126207.41935484 -0.722852037851561 -1.1235 -0.9813 1621208 Maybridge1_001992 COC(=O)c1cc(=O)c2cccc(OC)c2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C13 compound treatment 740800.0 -340000.0 -1.66 698770.0 -337000.0 -2.0 760490.0 -278357.41935484 -1.59429000973413 -3.0354 -0.9949 2070653 Maybridge1_001993 CC1(C)OC(=O)C(=Cc2ccc(OCc3ccc(F)cc3)cc2)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C14 compound treatment 759470.0 -322000.0 -1.57 750240.0 -285000.0 -1.7 695040.0 -343807.41935484 -1.96915438870038 -3.0224 -0.9955 2070654 Maybridge1_001994 COc1ccc(C(=O)C)c(OCc2ccccc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C15 compound treatment 956270.0 -125000.0 -0.61 881520.0 -154000.0 -0.91 860890.0 -177957.41935484 -1.01924977064764 -1.4681 -0.9796 1071664 Maybridge1_001995 CC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C16 compound treatment 934450.0 -147000.0 -0.72 1032870.0 -2410.0 -0.01 912720.0 -126127.41935484 -0.722393838457867 -0.8387 -0.8245 2070655 Maybridge1_001996 Cc1ccc(cc1)S(=O)(=O)N2CCC(=N2)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C17 compound treatment 772660.0 -308000.0 -1.51 710620.0 -325000.0 -1.93 677560.0 -361287.41935484 -2.06927095622261 -3.179 -0.9916 2070656 Maybridge1_001997 Clc1c(Cl)c(Cl)c(C#N)c(Cl)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C18 compound treatment 755520.0 -325000.0 -1.59 746000.0 -289000.0 -1.72 844860.0 -193987.41935484 -1.11106147415916 -2.5527 -0.9846 2070657 Maybridge1_001998 CC(=O)C1COc2ccc(C)cc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C19 compound treatment 977220.0 -104000.0 -0.51 895360.0 -140000.0 -0.83 939630.0 -99217.4193548399 -0.568267017403907 -1.1011 -0.9763 683 Maybridge1_001999 Cc1ncc([N+](=O)[O-])n1CCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C20 compound treatment 770310.0 -311000.0 -1.52 765190.0 -270000.0 -1.61 715360.0 -323487.41935484 -1.852771742702 -2.8733 -0.9964 2070658 Maybridge1_002000 CC(=O)Nc1cc(OCC=C)c(cc1C(=O)C)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C21 compound treatment 925300.0 -156000.0 -0.76 764220.0 -271000.0 -1.61 861240.0 -177607.41935484 -1.01724514830023 -1.9571 -0.9536 2070659 Maybridge1_002001 Sc1nc(c2cccs2)c(C#N)c(=O)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C22 compound treatment 936810.0 -144000.0 -0.7 930560.0 -105000.0 -0.62 938810.0 -100037.41935484 -0.572963561189275 -1.097 -0.9964 2070660 Maybridge1_002002 CCOC(=O)c1cc(=O)c2cc(I)ccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C23 mock treatment 984890.0 -96100.0 -0.47 925760.0 -110000.0 -0.65 1076090.0 37242.5806451601 0.213306598390348 -0.5239 -0.6307 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 C24 mock treatment 961310.0 -120000.0 -0.58 865800.0 -169000.0 -1.01 919290.0 -119557.41935484 -0.684764213250713 -1.3148 -0.9729 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D01 compound treatment 1025960.0 -55000.0 -0.27 973000.0 -62300.0 -0.37 958210.0 -80637.4193548399 -0.461850208218378 -0.6357 -0.9777 1012007 Maybridge1_002003 COc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D02 compound treatment 911290.0 -170000.0 -0.83 1025800.0 -9480.0 -0.06 1062430.0 23582.5806451601 0.135069051917026 -0.4332 -0.5146 1022157 Maybridge1_002004 NS(=O)(=O)c1ccc(NC(=O)CCC(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D03 compound treatment 44260.0 -1040000.0 -5.07 30150.0 -1010000.0 -5.98 39120.0 -999727.41935484 -5.72593121760092 -9.6811 -0.9976 1036639 Maybridge1_002005 O=c1c(c1c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D04 compound treatment 38800.0 -1040000.0 -5.09 24000.0 -1010000.0 -6.01 25790.0 -1013057.41935484 -5.80227869157525 -9.7617 -0.9976 1303231 Maybridge1_002006 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D05 compound treatment 959960.0 -121000.0 -0.59 877210.0 -158000.0 -0.94 893170.0 -145677.41935484 -0.83436631529194 -1.3658 -0.9833 1663982 Maybridge1_002007 CCOC(=O)Cc1c([nH]c(C)c1C(=O)OCc2ccccc2)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D06 compound treatment 973940.0 -107000.0 -0.52 931040.0 -104000.0 -0.62 969860.0 -68987.4193548399 -0.395124921511628 -0.8879 -0.9843 1010260 Maybridge1_002008 COc1ccccc1OCCOc2ccccc2OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D07 compound treatment 854560.0 -226000.0 -1.11 772800.0 -262000.0 -1.56 777010.0 -261837.41935484 -1.49967183493624 -2.4057 -0.9896 1062747 Maybridge1_002009 c1ccc(cc1)c2nc(c(o2)c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D08 compound treatment 953800.0 -127000.0 -0.62 983000.0 -52300.0 -0.31 920800.0 -118047.41935484 -0.676115699694731 -0.9286 -0.9578 1183034 Maybridge1_002010 OC1CCC(=O)N1CCc2cnc[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D09 compound treatment 959040.0 -122000.0 -0.6 886280.0 -149000.0 -0.89 984960.0 -53887.4193548399 -0.308639785951807 -1.0337 -0.9301 1038951 Maybridge1_002011 CCOC(=O)CC(=O)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D10 compound treatment 1087300.0 6320.0 0.03 905130.0 -130000.0 -0.77 920540.0 -118307.41935484 -0.677604847724237 -0.8202 -0.797 1126784 Maybridge1_002012 OC(=O)CC(Sc1nnc(S)s1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D11 compound treatment 616570.0 -464000.0 -2.27 638190.0 -397000.0 -2.36 583530.0 -455317.41935484 -2.60782706858619 -4.1789 -0.9982 1696384 Maybridge1_002013 CCN(CC)CCN(C)CC1c2ccccc2Oc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D12 compound treatment 695680.0 -385000.0 -1.88 554770.0 -481000.0 -2.86 568960.0 -469887.41935484 -2.69127663316278 -4.2904 -0.9855 2070661 Maybridge1_002014 O=C1/C(=C\C2CCC=CC2)/Cc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D13 compound treatment 949930.0 -131000.0 -0.64 876390.0 -159000.0 -0.94 932500.0 -106347.41935484 -0.609104038366922 -1.2668 -0.9792 2070662 Maybridge1_002015 CC(C)C(C#N)C(C#N)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D14 compound treatment 899580.0 -181000.0 -0.89 1085290.0 50000.0 0.3 804480.0 -234367.41935484 -1.34233761812642 -1.115 -0.6816 1561456 Maybridge1_002016 Nc1ccc2OCCCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D15 compound treatment 942610.0 -138000.0 -0.68 841050.0 -194000.0 -1.15 965770.0 -73077.4193548399 -0.418550365514255 -1.2988 -0.9262 1084645 Maybridge1_002017 [O-][N+](=O)c1ccc(OCc2ccccc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D16 compound treatment 975050.0 -106000.0 -0.52 821760.0 -214000.0 -1.27 859580.0 -179267.41935484 -1.02675278571938 -1.6247 -0.9485 1720787 Maybridge1_002018 Brc1cc2OCCOc2cc1C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D17 compound treatment 946240.0 -135000.0 -0.66 657940.0 -377000.0 -2.24 759040.0 -279807.41935484 -1.60259487374484 -2.6008 -0.9174 1060198 Maybridge1_002019 COC(=O)c1cccc2C(=O)c3ccccc3-c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D18 compound treatment 64120.0 -1020000.0 -4.97 36500.0 -999000.0 -5.94 44580.0 -994267.41935484 -5.69465910898127 -9.5852 -0.9972 2070663 Maybridge1_002020 CCCCCc1ccc(cc1)C(C)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D19 compound treatment 1216080.0 135000.0 0.66 1229570.0 194000.0 1.16 1051470.0 12622.5806451601 0.0722957349808905 1.0899 0.8179 1542963 Maybridge1_002021 COc1ccc2c(c1)nnc3nnc(SCC(=O)N4CCOCC4)n32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D20 compound treatment 880430.0 -201000.0 -0.98 864050.0 -171000.0 -1.02 891920.0 -146927.41935484 -0.841525680818416 -1.6394 -0.9968 1647393 Maybridge1_002022 CCC1(CC2CC3C1)CC(C2)(C3)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D21 compound treatment 448480.0 -632000.0 -3.09 468350.0 -567000.0 -3.37 158400.0 -880447.41935484 -5.04275592160254 -6.642 -0.9757 1026941 Maybridge1_002023 Clc1ccc2[nH]c3ccc(Cl)cc3c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D22 compound treatment 834260.0 -247000.0 -1.21 857370.0 -178000.0 -1.06 848250.0 -190597.41935484 -1.09164527485136 -1.937 -0.9984 1780030 Maybridge1_002024 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CC(=O)NC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D23 mock treatment 985730.0 -95200.0 -0.47 928270.0 -107000.0 -0.64 913800.0 -125047.41935484 -0.716208146642992 -1.0496 -0.9854 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 D24 mock treatment 1101760.0 20800.0 0.1 1022360.0 -12900.0 -0.08 1000910.0 -37937.4193548399 -0.217286281833982 -0.1112 -0.4414 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E01 compound treatment 1181030.0 100000.0 0.49 1185920.0 151000.0 0.9 1101540.0 62692.5806451601 0.359071280509385 1.0067 0.9306 1371050 Maybridge1_002025 COc1ccc(C(=O)N)c(Cl)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E02 compound treatment 1151650.0 70700.0 0.35 1031200.0 -4080.0 -0.02 1085440.0 46592.5806451601 0.266858652528383 0.3394 0.7766 1675178 Maybridge1_002026 CCCc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E03 compound treatment 971520.0 -109000.0 -0.53 863210.0 -172000.0 -1.02 983400.0 -55447.4193548399 -0.317574674128848 -1.0829 -0.9043 1018385 Maybridge1_002027 CCOC(=O)c1[nH]c(C)c(CC)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E04 compound treatment 919040.0 -162000.0 -0.79 840540.0 -195000.0 -1.16 1000250.0 -38597.4193548399 -0.221066426831961 -1.253 -0.8825 1079173 Maybridge1_002028 CCCCCCc1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E05 compound treatment 1013030.0 -67900.0 -0.33 934570.0 -101000.0 -0.6 939540.0 -99307.4193548399 -0.568782491721813 -0.8658 -0.9727 1330795 Maybridge1_002029 CCCCN1CC(=C(O)C1=O)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E06 compound treatment 904760.0 -176000.0 -0.86 764000.0 -271000.0 -1.61 935280.0 -103567.41935484 -0.593181609436041 -1.7709 -0.9212 2070664 Maybridge1_002030 C/C(=N\OC(=O)C(F)(F)F)/c1cc(cc2c1CCC2(C)C)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E07 compound treatment 40920.0 -1040000.0 -5.08 31210.0 -1000000.0 -5.97 29340.0 -1009507.41935484 -5.78194609348006 -9.7193 -0.9977 1032259 Maybridge1_002031 CC(=O)NC(CO)C(=O)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E08 compound treatment 786840.0 -294000.0 -1.44 766880.0 -268000.0 -1.6 728650.0 -310197.41935484 -1.77665336842451 -2.7769 -0.9963 1074369 Maybridge1_002032 Cc1c(OCc2ccccc2)cccc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E09 compound treatment 752660.0 -328000.0 -1.6 629080.0 -406000.0 -2.42 579050.0 -459797.41935484 -2.63348623463307 -3.8411 -0.9806 2070665 Maybridge1_002033 Cc1ccc(Oc2ncccc2C(F)(F)F)c3CCCc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E10 compound treatment 924800.0 -156000.0 -0.76 1080830.0 45600.0 0.27 1070270.0 31422.5806451601 0.179972592499079 -0.1802 -0.2173 2070666 Maybridge1_002034 COc1ccc(C(=O)C)c(NC(=O)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E11 compound treatment 781050.0 -300000.0 -1.47 733230.0 -302000.0 -1.8 780220.0 -258627.41935484 -1.48128658426425 -2.7383 -0.9954 2070667 Maybridge1_002035 Cc1nc(c(o1)c2ccccc2)c3ccc(cc3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E12 compound treatment 545290.0 -536000.0 -2.62 585080.0 -450000.0 -2.68 595270.0 -443577.41935484 -2.54058630756153 -4.5235 -0.9998 1026166 Maybridge1_002036 [O-][N+](=O)c1cc(OCc2ccccc2)c(OCc3ccccc3)c(OCc4ccccc4)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E13 compound treatment 908830.0 -172000.0 -0.84 923890.0 -111000.0 -0.66 825940.0 -212907.41935484 -1.21942563076789 -1.5721 -0.9688 2070668 Maybridge1_002037 Cc1cc(Oc2ncccc2[N+](=O)[O-])cc(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E14 compound treatment 937510.0 -143000.0 -0.7 894080.0 -141000.0 -0.84 967450.0 -71397.4193548399 -0.408928178246673 -1.1256 -0.9639 1174165 Maybridge1_002038 CCCc1c(SC(=O)N(C)C)ccc2c(C)cc(=O)oc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E15 compound treatment 855900.0 -225000.0 -1.1 834620.0 -201000.0 -1.19 782930.0 -255917.41935484 -1.46576507980285 -2.1701 -0.9924 2070669 Maybridge1_002039 CSc1cc(C)nc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E16 compound treatment 792590.0 -288000.0 -1.41 805890.0 -229000.0 -1.36 806630.0 -232217.41935484 -1.33002350942088 -2.3689 -0.9997 2070670 Maybridge1_002040 CCCc1c(O)c(ccc1SC(=O)N(C)C)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E17 compound treatment 933160.0 -148000.0 -0.72 888090.0 -147000.0 -0.88 937140.0 -101707.41935484 -0.582528473532645 -1.2586 -0.9867 2070671 Maybridge1_002041 Oc1ccc(cc1)n2nnnc2SCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E18 compound treatment 1063040.0 -17900.0 -0.09 896600.0 -139000.0 -0.82 912440.0 -126407.41935484 -0.723997536335797 -0.9447 -0.8582 1434029 Maybridge1_002042 CCCc1c(O)ccc2c(=O)cc(oc12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E19 compound treatment 52380.0 -1030000.0 -5.03 36680.0 -999000.0 -5.94 35810.0 -1003037.41935484 -5.74488921751502 -9.6467 -0.9975 1404645 Maybridge1_002043 CC(C)(C)c1ccc(Oc2cnn(c3ccccc3)c(=O)c2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E20 compound treatment 618190.0 -463000.0 -2.26 612680.0 -423000.0 -2.51 608190.0 -430657.41935484 -2.46658710547988 -4.1804 -0.999 2070672 Maybridge1_002044 CCOC(=O)c1ccc2oc3ccc(O)cc3c(=O)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E21 compound treatment 1061060.0 -19900.0 -0.1 983200.0 -52100.0 -0.31 1083430.0 44582.5806451601 0.255346392761811 -0.0876 -0.212 1027240 Maybridge1_002045 CCCCCCCCCCc1ccc(cc1)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E22 compound treatment 997350.0 -83600.0 -0.41 1095860.0 60600.0 0.36 1000590.0 -38257.4193548399 -0.21911907940876 -0.1544 -0.263 1016459 Maybridge1_002046 CCC(=O)NNc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E23 mock treatment 1066320.0 -14700.0 -0.07 1055630.0 20400.0 0.12 998290.0 -40557.4193548399 -0.232292311977474 -0.1056 -0.3888 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 E24 mock treatment 1049860.0 -31100.0 -0.15 1228420.0 193000.0 1.15 953280.0 -85567.4193548399 -0.490086745854797 0.2924 0.2324 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F01 compound treatment 1032270.0 -48700.0 -0.24 1065460.0 30200.0 0.18 1038970.0 122.580645160051 7.02079716137576E-4 -0.0334 -0.1119 1627859 Maybridge1_002047 CCOc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F02 compound treatment 1094920.0 13900.0 0.07 1088160.0 52900.0 0.31 986080.0 -52767.4193548399 -0.302224994440085 0.0464 0.1051 1177385 Maybridge1_002048 COC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F03 compound treatment 994320.0 -86700.0 -0.42 897030.0 -138000.0 -0.82 922140.0 -116707.41935484 -0.668440859850349 -1.105 -0.9684 1053852 Maybridge1_002049 N#CC(=c1ccc(=C(C#N)C#N)cc1)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F04 compound treatment 44370.0 -1040000.0 -5.06 30650.0 -1000000.0 -5.97 31960.0 -1006887.41935484 -5.76694006333657 -9.7028 -0.9976 1235461 Maybridge1_002050 OC(CN1CCCCCC1)Cn2c3ccc(Br)cc3c4cc(Br)ccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F05 compound treatment 692860.0 -388000.0 -1.9 819300.0 -216000.0 -1.28 656050.0 -382797.41935484 -2.1924693182022 -3.1021 -0.9784 1532455 Maybridge1_002051 COC(=O)CCc1c([nH]c(C)c1C(=O)OC(C)(C)C)C(=O)OCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F06 compound treatment 1050170.0 -30800.0 -0.15 1076920.0 41600.0 0.25 1012450.0 -26397.4193548399 -0.151191019293562 -0.0312 -0.0955 2070673 Maybridge1_002052 CC(=O)Nc1cccc(OCCOc2cccc(NC(=O)C)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F07 compound treatment 677620.0 -403000.0 -1.97 1030250.0 -5030.0 -0.03 538900.0 -499947.41935484 -2.86344505534346 -2.8083 -0.8079 1007924 Maybridge1_002053 c1c(noc1c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F08 compound treatment 952730.0 -128000.0 -0.63 890880.0 -144000.0 -0.86 878990.0 -159857.41935484 -0.915582157824276 -1.3861 -0.988 1452323 Maybridge1_002054 Cn1c(=O)c2c(O)cc(=O)oc2c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F09 compound treatment 1171390.0 90400.0 0.44 1173490.0 138000.0 0.82 955840.0 -83007.4193548399 -0.475424365256575 0.4551 0.4346 2070674 Maybridge1_002055 CCCCCc1ccc-2c(Cc3cc(ccc32)C(=O)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F10 compound treatment 1057210.0 -23800.0 -0.12 943470.0 -91800.0 -0.55 969240.0 -69607.4193548399 -0.39867596681276 -0.6124 -0.8928 1114824 Maybridge1_002056 OC(=O)c1ccc(Br)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F11 compound treatment 922300.0 -159000.0 -0.78 888480.0 -147000.0 -0.87 871810.0 -167037.41935484 -0.95670555340835 -1.5039 -0.9964 1029662 Maybridge1_002057 CC1(O)c2ccccc2-c3ccccc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F12 compound treatment 1288090.0 207000.0 1.01 968270.0 -67000.0 -0.4 1259360.0 220512.58064516 1.26298413442005 1.0834 0.65 2070675 Maybridge1_002058 CC(N1CCOCC1)C(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F13 compound treatment 1204920.0 124000.0 0.61 1004040.0 -31200.0 -0.19 1186290.0 147442.58064516 0.844476263204409 0.7299 0.6915 1039044 Maybridge1_002059 C(CC=C(c1ccccc1)c2ccccc2)C=C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F14 compound treatment 1106450.0 25500.0 0.12 972160.0 -63100.0 -0.38 994480.0 -44367.4193548399 -0.254114058102171 -0.2916 -0.6203 2070676 Maybridge1_002060 CC1(C)CC(C)(c2cccc3ccccc23)c4cccc5cccc1c45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F15 compound treatment 1011590.0 -69400.0 -0.34 1050980.0 15700.0 0.09 907680.0 -131167.41935484 -0.751260400260615 -0.5756 -0.6939 1260687 Maybridge1_002061 Cc1cccc(c1)C(=O)c2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F16 compound treatment 833790.0 -247000.0 -1.21 768920.0 -266000.0 -1.58 864540.0 -174307.41935484 -0.99834442331033 -2.1881 -0.9821 1004784 Maybridge1_002062 Oc1c(Cl)c(Cl)c(Cl)c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F17 compound treatment 405920.0 -675000.0 -3.3 415880.0 -619000.0 -3.68 559840.0 -479007.41935484 -2.74351136404395 -5.6147 -0.993 2070677 Maybridge1_002063 Oc1cc(cc2C(=O)c3cc(ccc3-c21)[N+](=O)[O-])[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F18 compound treatment 1021570.0 -59400.0 -0.29 1126170.0 90900.0 0.54 930660.0 -108187.41935484 -0.619642624421893 -0.2133 -0.2446 2070678 Maybridge1_002064 OCC(O)C(O)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F19 compound treatment 1001440.0 -79500.0 -0.39 1056180.0 20900.0 0.12 900710.0 -138137.41935484 -0.791181022436241 -0.6094 -0.6846 1685691 Maybridge1_002065 COc1ccc2c(c1)nnc3nnc(SCC(=O)NN)n32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F20 compound treatment 663770.0 -417000.0 -2.04 694830.0 -340000.0 -2.02 633700.0 -405147.41935484 -2.32047877381558 -3.6854 -0.998 1084281 Maybridge1_002066 CC(N)C1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F21 compound treatment 608800.0 -472000.0 -2.31 589310.0 -446000.0 -2.65 576160.0 -462687.41935484 -2.65003868773029 -4.3931 -0.998 1062012 Maybridge1_002067 Brc1ccc2[nH]c3c(Br)cc(Br)cc3c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F22 compound treatment 1103520.0 22500.0 0.11 997800.0 -37500.0 -0.22 1094050.0 55202.5806451601 0.316172362274745 0.1175 0.292 2070679 Maybridge1_002068 CCCCCCCCCCCC(=O)N1CC(=O)NC(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F23 mock treatment 1127920.0 46900.0 0.23 1075520.0 40200.0 0.24 1006740.0 -32107.4193548399 -0.183895001018501 0.1644 0.4337 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 F24 mock treatment 1021310.0 -59700.0 -0.29 900180.0 -135000.0 -0.8 983200.0 -55647.4193548399 -0.318720172613084 -0.8161 -0.8948 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G01 compound treatment 893180.0 -188000.0 -0.92 942770.0 -92500.0 -0.55 880810.0 -158037.41935484 -0.905158121617728 -1.3699 -0.9776 2070680 Maybridge1_002069 COc1ccc(/C=C/C#N)c(Cl)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G02 compound treatment 1204720.0 124000.0 0.6 1106360.0 71100.0 0.42 1080320.0 41472.5806451601 0.23753389133194 0.7302 0.9423 1089966 Maybridge1_002070 CCc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G03 compound treatment 1033620.0 -47400.0 -0.23 995650.0 -39600.0 -0.24 959230.0 -79617.4193548399 -0.456008165948774 -0.5329 -0.9465 2070681 Maybridge1_002071 CC(=O)C1=C(C)NC(=O)C1CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G04 compound treatment 972450.0 -109000.0 -0.53 985600.0 -49700.0 -0.3 950930.0 -87917.4193548399 -0.50354635304457 -0.7674 -0.9731 2070682 Maybridge1_002072 Cc1ccc(Br)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G05 compound treatment 983360.0 -97600.0 -0.48 905840.0 -129000.0 -0.77 858810.0 -180037.41935484 -1.03116295488369 -1.3151 -0.9583 1398285 Maybridge1_002073 COC(=O)Cc1c(OC(=O)C)[nH]c(C)c1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G06 compound treatment 999560.0 -81400.0 -0.4 932900.0 -102000.0 -0.61 973220.0 -65627.4193548399 -0.375880546976463 -0.7982 -0.975 2070683 Maybridge1_002074 CC1(C)C2CCC1(C)/C(=N/O)/C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G07 compound treatment 1071470.0 -9510.0 -0.05 1172700.0 137000.0 0.82 1043160.0 4312.58064516005 0.0247002729608828 0.4592 0.5608 1472613 Maybridge1_002075 Cc1ccc(OC(C)(C)C(=O)O)c2CCCc21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G08 compound treatment 921520.0 -159000.0 -0.78 917000.0 -118000.0 -0.7 860000.0 -178847.41935484 -1.02434723890249 -1.4473 -0.9868 1092704 Maybridge1_002076 COc1cc(Br)c(CCC#N)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G09 compound treatment 1251740.0 171000.0 0.83 1086880.0 51600.0 0.31 1152570.0 113722.58064516 0.651345218762212 1.0349 0.9391 1252404 Maybridge1_002077 COc1ccccc1C2OC(=O)CC2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G10 compound treatment 1125000.0 44000.0 0.22 1056970.0 21700.0 0.13 1085800.0 46952.5806451601 0.268920549800008 0.3539 0.9625 2732 Maybridge1_002078 Cc1cc(=O)oc2cc(O)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G11 compound treatment 1224900.0 144000.0 0.7 1123570.0 88300.0 0.53 1131040.0 92192.5806451601 0.528032306934202 1.014 0.99 2070684 Maybridge1_002079 O=C(C1COC(=O)C1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G12 compound treatment 997670.0 -83300.0 -0.41 815940.0 -219000.0 -1.3 947730.0 -91117.4193548399 -0.521874328792347 -1.2893 -0.8815 2070685 Maybridge1_002080 COc1ccc2C(=O)C(CCc2c1)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G13 compound treatment 58320.0 -1020000.0 -5.0 50880.0 -984000.0 -5.85 45500.0 -993347.41935484 -5.68938981595379 -9.5492 -0.9977 1639767 Maybridge1_002081 O=C1Cc2ccccc2C(=O)c3ccsc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G14 compound treatment 1055270.0 -25700.0 -0.13 1028610.0 -6670.0 -0.04 966750.0 -72097.4193548399 -0.412937422941499 -0.3338 -0.7702 1686304 Maybridge1_002082 CCOC(=O)c1cc(=O)c2ccc(O)cc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G15 compound treatment 1137140.0 56200.0 0.27 1139700.0 104000.0 0.62 975270.0 -63577.4193548399 -0.364139187513043 0.3067 0.3981 1339494 Maybridge1_002083 CC(=O)Nc1cccc(C)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G16 compound treatment 786560.0 -294000.0 -1.44 729120.0 -306000.0 -1.82 798080.0 -240767.41935484 -1.37899356962197 -2.6778 -0.9921 1515846 Maybridge1_002084 CCCc1c(O)ccc2C(=O)CC(C)(CCC(=O)OC)Oc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G17 compound treatment 1127920.0 46900.0 0.23 973450.0 -61800.0 -0.37 966270.0 -72577.4193548399 -0.415686619303665 -0.3198 -0.5327 1660066 Maybridge1_002085 CCOC(=O)c1cc2cc(Br)cc(Br)c2oc1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G18 compound treatment 995690.0 -85300.0 -0.42 899390.0 -136000.0 -0.81 825230.0 -213617.41935484 -1.22349215038693 -1.4135 -0.9273 2070686 Maybridge1_002086 CCCc1c(O)c(ccc1OCc2ccccc2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G19 compound treatment 904920.0 -176000.0 -0.86 973630.0 -61600.0 -0.37 849390.0 -189457.41935484 -1.08511593349121 -1.3348 -0.9318 1397141 Maybridge1_002087 O=C(ON1C(=O)C2C3OC(C=C3)C2C1=O)c4cccnc4Oc5ccccc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G20 compound treatment 697710.0 -383000.0 -1.87 733020.0 -302000.0 -1.8 734420.0 -304427.41935484 -1.7436057371543 -3.1255 -0.9996 2070687 Maybridge1_002088 CS/C(=N/c1ccccc1)/Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G21 compound treatment 1112160.0 31200.0 0.15 1055110.0 19800.0 0.12 952550.0 -86297.4193548399 -0.494267815322258 -0.1293 -0.2438 1080745 Maybridge1_002089 CC(=O)c1ccc(cc1)c2ccc(cc2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G22 compound treatment 1022780.0 -58200.0 -0.28 964080.0 -71200.0 -0.42 1053650.0 14802.5806451601 0.0847816684590634 -0.3597 -0.6957 2070688 Maybridge1_002090 CCCc1ccc(OC)cc1NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G23 mock treatment 995200.0 -85800.0 -0.42 989920.0 -45400.0 -0.27 933210.0 -105637.41935484 -0.605037518747884 -0.747 -0.953 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 G24 mock treatment 1086570.0 5590.0 0.03 1162320.0 127000.0 0.76 1053700.0 14852.5806451601 0.0850680430801224 0.5011 0.6587 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H01 compound treatment 1045760.0 -35200.0 -0.17 1124990.0 89700.0 0.53 942360.0 -96487.4193548399 -0.552630963094085 -0.1104 -0.1402 1274795 Maybridge1_002091 CCCOc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H02 compound treatment 1384920.0 304000.0 1.49 1165140.0 130000.0 0.77 1200420.0 161572.58064516 0.925405731115686 1.8375 0.9607 1254947 Maybridge1_002092 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H03 compound treatment 842200.0 -239000.0 -1.17 712740.0 -323000.0 -1.92 768220.0 -270627.41935484 -1.55001649331841 -2.6758 -0.9808 1026066 Maybridge1_002093 CCOC(=O)C1c2ccccc2Oc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H04 compound treatment 742290.0 -339000.0 -1.65 667880.0 -367000.0 -2.18 698790.0 -340057.41935484 -1.94767629212095 -3.3412 -0.9937 1033421 Maybridge1_002094 Nc1cccc2-c3ccccc3C(=O)c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H05 compound treatment 1170490.0 89500.0 0.44 950730.0 -84500.0 -0.5 928730.0 -110117.41935484 -0.630696684794771 -0.4019 -0.438 2070689 Maybridge1_002095 O=C1N(CCCCCN2C(=O)c3ccccc3S2(=O)=O)S(=O)(=O)c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H06 compound treatment 1096430.0 15500.0 0.08 948340.0 -86900.0 -0.52 1048020.0 9172.58064516005 0.0525358861278187 -0.2246 -0.4276 2070690 Maybridge1_002096 COc1cccc(OCCOc2cccc(OC)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H07 compound treatment 47490.0 -1030000.0 -5.05 37700.0 -998000.0 -5.93 33770.0 -1005077.41935484 -5.75657330205423 -9.6638 -0.9977 1022179 Maybridge1_002097 CN(C)Cc1cc(O)c(CN(C)C)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H08 compound treatment 1026740.0 -54200.0 -0.26 1169920.0 135000.0 0.8 967520.0 -71327.4193548399 -0.40852725377719 0.0734 0.0783 2070691 Maybridge1_002098 O[C@H]1C2C3C4C2C5CC4C([C@@H]3O)C15 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H09 compound treatment 954340.0 -127000.0 -0.62 951150.0 -84100.0 -0.5 869490.0 -169357.41935484 -0.969993335825488 -1.2061 -0.9613 1011924 Maybridge1_002099 CC(=O)c1ccc-2c(Cc3ccccc32)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H10 compound treatment 1134590.0 53600.0 0.26 1027520.0 -7760.0 -0.05 963920.0 -74927.4193548399 -0.429146226493439 -0.1232 -0.244 1047733 Maybridge1_002100 N#CCCC(CCC#N)(C#N)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H11 compound treatment 1022500.0 -58500.0 -0.29 792800.0 -242000.0 -1.44 867200.0 -171647.41935484 -0.983109293469991 -1.565 -0.885 1520838 Maybridge1_002101 CCC(C#N)(c1ccccc1)c2ccc(N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H12 compound treatment 1297950.0 217000.0 1.06 1305770.0 270000.0 1.61 1207280.0 168432.58064516 0.964696329124982 2.0977 0.9736 1472477 Maybridge1_002102 OC(=O)C1(CC2CC3CC(O)(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H13 compound treatment 1063560.0 -17400.0 -0.09 1330400.0 295000.0 1.75 1149810.0 110962.58064516 0.635537339679755 1.331 0.7124 3177555 Maybridge1_002103 Cc1ccc(cc1)S(=O)(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)OCC=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H14 compound treatment 881720.0 -199000.0 -0.97 821160.0 -214000.0 -1.27 788440.0 -250407.41935484 -1.43420659656215 -2.1252 -0.9881 2070693 Maybridge1_002104 [O-][N+](=O)c1ccc2[nH]c3ccc(cc3c2c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H15 compound treatment 643080.0 -438000.0 -2.14 650680.0 -385000.0 -2.29 598150.0 -440697.41935484 -2.52409112938853 -4.0129 -0.9977 1073082 Maybridge1_002105 c1csc(c1)c2nc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H16 compound treatment 1137640.0 56700.0 0.28 1002770.0 -32500.0 -0.19 1159070.0 120222.58064516 0.688573919499883 0.4458 0.5813 2070694 Maybridge1_002106 NC(=O)C1CC1(Cl)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H17 compound treatment 1086900.0 5920.0 0.03 906950.0 -128000.0 -0.76 1118420.0 79572.5806451601 0.455751352578907 -0.1607 -0.1808 1041298 Maybridge1_002107 OC(=O)c1cccc2Cc3ccccc3-c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H18 compound treatment 655950.0 -425000.0 -2.08 490580.0 -545000.0 -3.24 155880.0 -882967.41935484 -5.05718920250391 -5.9888 -0.9425 2070695 Maybridge1_002108 CCCCCc1ccc(/C=N/O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H19 compound treatment 1121670.0 40700.0 0.2 1000010.0 -35300.0 -0.21 1147810.0 108962.58064516 0.624082354837394 0.354 0.5148 2070696 Maybridge1_002109 OC(=O)C(F)(F)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H20 compound treatment 687290.0 -394000.0 -1.92 593220.0 -442000.0 -2.63 532520.0 -506327.41935484 -2.89998645699059 -4.3025 -0.9866 1132443 Maybridge1_002110 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(O)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H21 compound treatment 854920.0 -226000.0 -1.1 935230.0 -100000.0 -0.59 904170.0 -134677.41935484 -0.771363898658958 -1.4265 -0.9686 1421410 Maybridge1_002111 OCC(O)Cn1c2ccccc2c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H22 compound treatment 1279480.0 199000.0 0.97 949070.0 -86200.0 -0.51 1229850.0 191002.58064516 1.09396583307102 0.8956 0.5781 1405657 Maybridge1_002112 O=C1CN(CC(=O)N1)S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H23 mock treatment 1174100.0 93100.0 0.45 1062520.0 27200.0 0.16 1234770.0 195922.58064516 1.12214509578323 1.0041 0.8219 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 H24 mock treatment 1154610.0 73600.0 0.36 1146530.0 111000.0 0.66 1152330.0 113482.58064516 0.649970620581129 0.9649 0.97 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I01 compound treatment 983290.0 -97700.0 -0.48 1062080.0 26800.0 0.16 1047420.0 8572.58064516005 0.0490993906751105 -0.1552 -0.307 2070697 Maybridge1_002113 CCOC(=O)c1ccc(OC)c(OC)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I02 compound treatment 1264990.0 184000.0 0.9 866330.0 -169000.0 -1.0 1283580.0 244732.58064516 1.40170400086103 0.7483 0.3848 1083770 Maybridge1_002114 N#Cc1nccc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I03 compound treatment 885010.0 -196000.0 -0.96 836660.0 -199000.0 -1.18 884390.0 -154457.41935484 -0.884653698749903 -1.7454 -0.9923 1679978 Maybridge1_002115 CCOC(=O)C1=C(N)C(=O)N(C1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I04 compound treatment 1229870.0 149000.0 0.73 942850.0 -92400.0 -0.55 1097810.0 58962.5806451601 0.337707733778382 0.2977 0.3061 1071677 Maybridge1_002116 CN(C)c1cccc2cccc(N(C)C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I05 compound treatment 1003690.0 -77300.0 -0.38 1161460.0 126000.0 0.75 1120540.0 81692.5806451601 0.467893636511809 0.4853 0.5048 1007323 Maybridge1_002117 CCOC(=O)c1[nH]c(C)c(C(=O)C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I06 compound treatment 1112930.0 32000.0 0.16 1243130.0 208000.0 1.24 1041170.0 2322.58064516005 0.0133025630427341 0.8114 0.6513 2070698 Maybridge1_002118 Cc1oc(nc1CC(=O)O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I07 compound treatment 972180.0 -109000.0 -0.53 979200.0 -56100.0 -0.33 924520.0 -114327.41935484 -0.65480942788794 -0.8775 -0.9675 1275946 Maybridge1_002119 OC(C(=O)c1cccs1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I08 compound treatment 985250.0 -95700.0 -0.47 995700.0 -39600.0 -0.24 948760.0 -90087.4193548399 -0.515975011598531 -0.7038 -0.9574 1204024 Maybridge1_002120 N#CCCc1cccc(OCc2ccccc2)c1OCc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I09 compound treatment 1116050.0 35100.0 0.17 1131590.0 96300.0 0.57 911780.0 -127067.41935484 -0.727777681333776 0.0094 0.01 2070699 Maybridge1_002121 Clc1ccc(C(=O)NCCSC(=O)c2ccc(Cl)cc2Cl)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I10 compound treatment 539170.0 -542000.0 -2.65 533790.0 -501000.0 -2.98 457600.0 -581247.41935484 -3.32909018918541 -5.1721 -0.9957 2070700 Maybridge1_002122 Nc1nnc(s1)c2ccc(o2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I11 compound treatment 937140.0 -144000.0 -0.7 1126780.0 91500.0 0.54 1044390.0 5542.58064516005 0.0317450886389344 -0.0733 -0.0824 2070701 Maybridge1_002123 [O-][N+](=O)c1cccnc1Oc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I12 compound treatment 1351070.0 270000.0 1.32 1031680.0 -3600.0 -0.02 1228870.0 190022.58064516 1.08835289049826 1.3779 0.8055 1928073 Maybridge1_002124 COC(=O)c1cccc(OC)c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I13 compound treatment 1185760.0 105000.0 0.51 1328240.0 293000.0 1.74 1280010.0 241162.58064516 1.38125685291742 2.0989 0.92 2070702 Maybridge1_002125 CCCCCc1ccc(cc1)c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I14 compound treatment 924810.0 -156000.0 -0.76 884990.0 -150000.0 -0.89 888440.0 -150407.41935484 -0.861457354444123 -1.4539 -0.9978 1727984 Maybridge1_002126 COC(=O)c1ccc(cc1)C2=NC(C)(C)CO2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I15 compound treatment 1097050.0 16100.0 0.08 1029550.0 -5730.0 -0.03 987130.0 -51717.4193548399 -0.296211127397846 -0.1453 -0.4714 2070703 Maybridge1_002127 [O-][N+](=O)c1ccc(Sc2ccccn2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I16 compound treatment 1191390.0 110000.0 0.54 1161040.0 126000.0 0.75 1075850.0 37002.5806451601 0.211932000209265 0.8656 0.9148 1698123 Maybridge1_002128 COc1ccc2nc(N)sc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I17 compound treatment 1307790.0 227000.0 1.11 966310.0 -69000.0 -0.41 1224820.0 185972.58064516 1.06515654619248 1.018 0.6399 2070704 Maybridge1_002129 Nc1cccnc1Sc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I18 compound treatment 674750.0 -406000.0 -1.98 688200.0 -347000.0 -2.06 493870.0 -544977.41935484 -3.12135403906921 -4.1396 -0.9773 1022546 Maybridge1_002130 CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I19 compound treatment 943810.0 -137000.0 -0.67 947170.0 -88100.0 -0.52 872840.0 -166007.41935484 -0.950806236214534 -1.2384 -0.9707 2070705 Maybridge1_002131 COC(=O)c1cccnc1Oc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I20 compound treatment 1055200.0 -25800.0 -0.13 899380.0 -136000.0 -0.81 1003360.0 -35487.4193548399 -0.203253925402091 -0.6566 -0.7791 2070706 Maybridge1_002132 CS/C(=N/C(C)C)/NC(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I21 compound treatment 1028440.0 -52500.0 -0.26 1095090.0 59800.0 0.36 1079470.0 40622.5806451601 0.232665522773937 0.1915 0.3857 1111975 Maybridge1_002133 Cc1cc(C)n(C)c(=O)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I22 compound treatment 1217990.0 137000.0 0.67 1096000.0 60700.0 0.36 1040500.0 1652.58064516005 0.00946514312054333 0.6004 0.7894 1018233 Maybridge1_002134 CCN(CC)S(=O)(=O)c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I23 mock treatment 1064280.0 -16700.0 -0.08 1212100.0 177000.0 1.05 1035940.0 -2907.41935483995 -0.0166522223200385 0.5504 0.5218 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 I24 mock treatment 1085380.0 4400.0 0.02 1129920.0 94600.0 0.56 1003700.0 -35147.4193548399 -0.201306577978889 0.2211 0.3697 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J01 compound treatment 1046610.0 -34400.0 -0.17 931150.0 -104000.0 -0.62 937040.0 -101807.41935484 -0.583101222774764 -0.7911 -0.9125 2070707 Maybridge1_002135 CCCCOc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J02 compound treatment 1245280.0 164000.0 0.8 1018770.0 -16500.0 -0.1 1244080.0 205232.58064516 1.17546805022442 1.0855 0.7608 1169013 Maybridge1_002136 Cc1c(NS(=O)(=O)c2ccc(NC(=O)CCC(=O)O)cc2)c(=O)n(c3ccccc3)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J03 compound treatment 1115400.0 34400.0 0.17 1042610.0 7330.0 0.04 869860.0 -168987.41935484 -0.967874163629652 -0.4365 -0.4439 1075281 Maybridge1_002137 Cc1ccc2ncccc2c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J04 compound treatment 1133520.0 52500.0 0.26 1163130.0 128000.0 0.76 1187100.0 148252.58064516 0.849115532065565 1.0774 0.9222 2070708 Maybridge1_002138 OC(=O)c1cccc2cccc(Br)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J05 compound treatment 1233920.0 153000.0 0.75 1182990.0 148000.0 0.88 1147310.0 108462.58064516 0.621218608626804 1.2972 0.9903 2070709 Maybridge1_002139 CC(C)(C)c1cc2CCc3cc(cc(c1)c23)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J06 compound treatment 933340.0 -148000.0 -0.72 930240.0 -105000.0 -0.62 846720.0 -192127.41935484 -1.10040833825576 -1.4124 -0.9697 1056658 Maybridge1_002140 Clc1ccc(OCCOc2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J07 compound treatment 1073440.0 -7540.0 -0.04 1019470.0 -15800.0 -0.09 1105050.0 66202.5806451601 0.379174778907727 0.1434 0.3654 2070710 Maybridge1_002141 [O-][N+](=O)c1sccc1CS(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J08 compound treatment 1144120.0 63100.0 0.31 1181490.0 146000.0 0.87 1091290.0 52442.5806451601 0.300364483192287 0.8535 0.8797 2070711 Maybridge1_002142 COC(F)(C(=O)N)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J09 compound treatment 1100920.0 19900.0 0.1 1074420.0 39100.0 0.23 1058560.0 19712.5806451601 0.112903656247058 0.2558 0.9254 1289810 Maybridge1_002143 Brc1ccc(CC(=O)c2ccc-3c(Cc4ccccc43)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J10 compound treatment 1204960.0 124000.0 0.61 1215430.0 180000.0 1.07 997250.0 -41597.4193548399 -0.238248904095502 0.8307 0.6627 1007301 Maybridge1_002144 NC(=O)C(CCC#N)(CCC#N)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J11 compound treatment 1113940.0 33000.0 0.16 1255600.0 220000.0 1.31 1165760.0 126912.58064516 0.726890843797579 1.2691 0.8422 2070712 Maybridge1_002145 CC(=O)/C(=N/NC(=O)CC#N)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J12 compound treatment 1293090.0 212000.0 1.04 1332840.0 298000.0 1.77 1293290.0 254442.58064516 1.45731795227069 2.4613 0.9784 2070713 Maybridge1_002146 CO[C@H]1CC2(N3CC=C2C=C1)c4cc(OC)c(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc4CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J13 compound treatment 1070340.0 -10600.0 -0.05 987840.0 -47400.0 -0.28 958880.0 -79967.4193548399 -0.458012788296187 -0.4573 -0.8462 2070714 Maybridge1_002147 Cc1csc(c1c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J14 compound treatment 813560.0 -267000.0 -1.31 847040.0 -188000.0 -1.12 760320.0 -278527.41935484 -1.59526368344573 -2.3216 -0.9895 2070715 Maybridge1_002148 Cn1c2ccccc2c3cc(ccc13)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J15 compound treatment 848110.0 -233000.0 -1.14 752230.0 -283000.0 -1.68 818990.0 -219857.41935484 -1.25923170309509 -2.3557 -0.9855 2070716 Maybridge1_002149 Cn1c(nc2ccccc12)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J16 compound treatment 1035330.0 -45600.0 -0.22 1149600.0 114000.0 0.68 1008440.0 -30407.4193548399 -0.174158263902495 0.1632 0.2216 1368311 Maybridge1_002150 Clc1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J17 compound treatment 1156370.0 75400.0 0.37 1086200.0 50900.0 0.3 1107200.0 68352.5806451601 0.391488887613265 0.6135 0.9944 1055459 Maybridge1_002151 OC(=O)C1Cc2c(CN1)[nH]c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J18 compound treatment 1109160.0 28200.0 0.14 961980.0 -73300.0 -0.44 1071700.0 32852.5806451601 0.188162906661367 -0.0635 -0.1285 2070717 Maybridge1_002152 [O-][N+](=O)c1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J19 compound treatment 1203720.0 123000.0 0.6 1030850.0 -4430.0 -0.03 1024080.0 -14767.4193548399 -0.0845802824352361 0.2822 0.4655 1059900 Maybridge1_002153 OC(=O)c1cc(Br)c(cc1Br)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J20 compound treatment 1191400.0 110000.0 0.54 1192640.0 157000.0 0.94 1058370.0 19522.5806451601 0.111815432687034 0.9163 0.8438 2070718 Maybridge1_002154 Cc1c(NC(=O)/C=N/O)c(=O)n(c2ccccc2)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J21 compound treatment 879620.0 -201000.0 -0.98 877040.0 -158000.0 -0.94 819540.0 -219307.41935484 -1.25608158226344 -1.8365 -0.9914 1159242 Maybridge1_002155 Cc1ccc(cc1)S(=O)(=O)Nc2ccc3ncccc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J22 compound treatment 1318850.0 238000.0 1.16 1032820.0 -2460.0 -0.01 1287210.0 248362.58064516 1.42249479834992 1.4838 0.8078 1117231 Maybridge1_002156 BrC1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J23 mock treatment 1192970.0 112000.0 0.55 996720.0 -38600.0 -0.23 1278210.0 239362.58064516 1.3709473665593 0.9751 0.6527 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 J24 mock treatment 1223220.0 142000.0 0.69 1218810.0 184000.0 1.09 1100000.0 61152.5806451601 0.350250942180767 1.2336 0.9203 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K01 compound treatment 519870.0 -561000.0 -2.74 441340.0 -594000.0 -3.53 507270.0 -531577.41935484 -3.04460564062539 -5.3797 -0.9946 1050460 Maybridge1_002157 OC1(CCNCC1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K02 compound treatment 1095840.0 14900.0 0.07 1094030.0 58800.0 0.35 1167310.0 128462.58064516 0.735768457050409 0.6684 0.8174 1051267 Maybridge1_002158 Oc1nc2cccnc2nc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K03 compound treatment 988990.0 -92000.0 -0.45 952070.0 -83200.0 -0.49 875240.0 -163607.41935484 -0.937060254403702 -1.0862 -0.9436 1003036 Maybridge1_002159 CCOC(=O)c1[nH]c(C)c(C(=O)OCC)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K04 compound treatment 1149070.0 68100.0 0.33 1133120.0 97800.0 0.58 964170.0 -74677.4193548399 -0.427714353388144 0.2811 0.3535 1037780 Maybridge1_002160 CCc1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K05 compound treatment 887100.0 -194000.0 -0.95 796320.0 -239000.0 -1.42 798080.0 -240767.41935484 -1.37899356962197 -2.1635 -0.9856 1010424 Maybridge1_002161 C(CNc1ccccc1)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K06 compound treatment 1060810.0 -20200.0 -0.1 925560.0 -110000.0 -0.65 904160.0 -134687.41935484 -0.77142117358317 -0.879 -0.8659 2070719 Maybridge1_002162 COc1ccc2nccc(C(=O)C3CC4CCN3C(C4)C=C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K07 compound treatment 986750.0 -94200.0 -0.46 775840.0 -259000.0 -1.54 775520.0 -263327.41935484 -1.50820579864379 -2.0273 -0.919 2070720 Maybridge1_002163 COc1ccc(C)c2CCCc21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K08 compound treatment 1194890.0 114000.0 0.56 1115100.0 79800.0 0.47 947140.0 -91707.4193548399 -0.525253549320843 0.2921 0.3244 2070721 Maybridge1_002164 COc1c(O)c(C(=O)C)c(OC)c2ccoc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K09 compound treatment 1301350.0 220000.0 1.08 1334580.0 299000.0 1.78 1127720.0 88872.5806451601 0.509017032095883 1.9431 0.9073 2070722 Maybridge1_002165 Fc1ccc(cc1)C(=O)NCCSC(=O)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K10 compound treatment 1104490.0 23500.0 0.11 1188270.0 153000.0 0.91 1104580.0 65732.5806451601 0.376482857469773 0.809 0.8161 1231125 Maybridge1_002166 CCOC(=O)c1cc(=O)c2c(O)c(CC=C)ccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K11 compound treatment 1212420.0 131000.0 0.64 1223370.0 188000.0 1.12 1205040.0 166192.58064516 0.951866746101539 1.5661 0.977 2070723 Maybridge1_002167 COc1ccc(Oc2ncccc2[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K12 compound treatment 1312730.0 232000.0 1.13 1197160.0 162000.0 0.96 1069440.0 30592.5806451601 0.175218773789499 1.3107 0.8758 1174068 Maybridge1_002168 COc1c(OC)c(sc1C(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K13 compound treatment 991110.0 -89900.0 -0.44 927890.0 -107000.0 -0.64 912700.0 -126147.41935484 -0.72250838830629 -1.0393 -0.9809 2070724 Maybridge1_002169 COc1cc(ccc1N2CCCC2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K14 compound treatment 1232860.0 152000.0 0.74 1151360.0 116000.0 0.69 1132280.0 93432.5806451601 0.535134397536465 1.1359 0.9911 2070725 Maybridge1_002170 CCOCCOc1ccc2oc(cc(=O)c2c1)C(=O)CC(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K15 compound treatment 1300690.0 220000.0 1.07 1052210.0 16900.0 0.1 1188830.0 149982.58064516 0.859024093954207 1.1739 0.8515 1283944 Maybridge1_002171 Cc1cccc(Oc2ncccc2N)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K16 compound treatment 1204370.0 123000.0 0.6 1153620.0 118000.0 0.7 1206360.0 167512.58064516 0.959427036097497 1.3083 0.9808 1216999 Maybridge1_002172 CC1(C)CC(=O)C=C(C1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K17 compound treatment 1131520.0 50500.0 0.25 1221840.0 187000.0 1.11 1200230.0 161382.58064516 0.924317507555662 1.3167 0.8988 2070726 Maybridge1_002173 CN(C)/C=N/c1cc(on1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K18 compound treatment 1177840.0 96900.0 0.47 1116420.0 81100.0 0.48 1055520.0 16672.5806451601 0.0954920792866704 0.6069 0.8892 1502251 Maybridge1_002174 CCn1c(cc(=O)c2cc(OCC=C)ccc12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K19 compound treatment 1113940.0 33000.0 0.16 1145310.0 110000.0 0.65 1191360.0 152512.58064516 0.873514649779793 0.9751 0.8838 2070727 Maybridge1_002175 CC(C)n1cc(nc1C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K20 compound treatment 1037470.0 -43500.0 -0.21 1059040.0 23800.0 0.14 1178190.0 139342.58064516 0.79808357459285 0.4196 0.5008 1514172 Maybridge1_002176 CCC(=O)c1ccc(SC(=O)N(C)C)cc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K21 compound treatment 996820.0 -84200.0 -0.41 1211680.0 176000.0 1.05 894020.0 -144827.41935484 -0.829497946733937 -0.1107 -0.0791 1721896 Maybridge1_002177 Oc1ccc(cc1)C(C#N)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K22 compound treatment 970300.0 -111000.0 -0.54 1178420.0 143000.0 0.85 992000.0 -46847.4193548399 -0.268318239306698 0.0243 0.0233 1075100 Maybridge1_002178 Cc1cc2OCCOc2cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K23 mock treatment 1049130.0 -31800.0 -0.16 978930.0 -56300.0 -0.34 1043150.0 4302.58064516005 0.0246429980366709 -0.2691 -0.7267 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 K24 mock treatment 1237660.0 157000.0 0.77 1081140.0 45900.0 0.27 1126360.0 87512.5806451601 0.501227642403078 0.8888 0.9309 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L01 compound treatment 1026280.0 -54700.0 -0.27 1124510.0 89200.0 0.53 920410.0 -118437.41935484 -0.678349421738991 -0.2396 -0.2657 2070728 Maybridge1_002179 CCCCCCOc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L02 compound treatment 1218560.0 138000.0 0.67 1130130.0 94900.0 0.56 1285890.0 247042.58064516 1.41493450835396 1.5307 0.9193 2070729 Maybridge1_002180 CC(=O)c1ccc2OCCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L03 compound treatment 1361120.0 280000.0 1.37 1233890.0 199000.0 1.18 1147330.0 108482.58064516 0.621333158475228 1.8308 0.9577 2070730 Maybridge1_002181 CCCCCCCCCCc1ccc(cc1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L04 compound treatment 1129050.0 48100.0 0.23 1115230.0 80000.0 0.48 1064640.0 25792.5806451601 0.147726810167834 0.4954 0.8999 1027383 Maybridge1_002182 Cn1c(=O)cc(O)c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L05 compound treatment 1100480.0 19500.0 0.1 974300.0 -61000.0 -0.36 982910.0 -55937.4193548399 -0.320381145415226 -0.3393 -0.688 2070731 Maybridge1_002183 FC(F)(F)c1cnc(/N=C/N2CCOCC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L06 compound treatment 1410960.0 330000.0 1.61 1024440.0 -10800.0 -0.06 1132550.0 93702.5806451601 0.536680820490184 1.2035 0.7077 2070732 Maybridge1_002184 COc1ccc(OCCOc2ccc(OC)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L07 compound treatment 1129150.0 48200.0 0.24 771480.0 -264000.0 -1.57 1007040.0 -31807.4193548399 -0.182176753292147 -0.875 -0.548 1135835 Maybridge1_002185 Sc1nc2cc3OCCOc3cc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L08 compound treatment 1368520.0 288000.0 1.4 1127630.0 92400.0 0.55 1221610.0 182762.58064516 1.0467712955205 1.7325 0.9436 1660986 Maybridge1_002186 NC1=C(C(=O)NC1=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L09 compound treatment 816000.0 -265000.0 -1.29 814130.0 -221000.0 -1.32 767740.0 -271107.41935484 -1.55276568968058 -2.4032 -0.9965 1056325 Maybridge1_002187 O=C(c1ccccc1)c2ccc-3c(Cc4ccccc43)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L10 compound treatment 1148060.0 67100.0 0.33 1057510.0 22200.0 0.13 1111480.0 72632.5806451601 0.416002555175916 0.5057 0.9265 1004888 Maybridge1_002188 N#CCCn1c2ccccc2c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L11 compound treatment 1326410.0 245000.0 1.2 1132800.0 97500.0 0.58 1178650.0 139802.58064516 0.800718221106592 1.4894 0.9584 1101325 Maybridge1_002189 OC1CN(C1)C(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L12 compound treatment 1088280.0 7300.0 0.04 1137030.0 102000.0 0.61 1055420.0 16572.5806451601 0.0949193300445524 0.4247 0.6923 2070733 Maybridge1_002190 COC(=O)Cc1nc(sc1C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L13 compound treatment 1008370.0 -72600.0 -0.35 1297570.0 262000.0 1.56 1187610.0 148762.58064516 0.852036553200367 1.1876 0.6553 2070734 Maybridge1_002191 Cc1c(Br)sc(Br)c1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L14 compound treatment 1321120.0 240000.0 1.17 1364990.0 330000.0 1.96 1259380.0 220532.58064516 1.26309868426847 2.5386 0.9724 1019205 Maybridge1_002192 OC(=O)c1cccc2-c3ccccc3C(=O)c21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L15 compound treatment 1041850.0 -39100.0 -0.19 984330.0 -50900.0 -0.3 1008880.0 -29967.4193548399 -0.171638167237176 -0.3844 -0.9677 2070735 Maybridge1_002193 c1nnc2nnc3ccccc3n12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L16 compound treatment 1187150.0 106000.0 0.52 1121170.0 85900.0 0.51 1148700.0 109852.58064516 0.629179823092245 0.9576 0.9953 1329133 Maybridge1_002194 Brc1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L17 compound treatment 671200.0 -410000.0 -2.0 752500.0 -283000.0 -1.68 770010.0 -268837.41935484 -1.5397642818845 -3.0157 -0.9939 2070736 Maybridge1_002195 COc1cc(CC/C(=N\O)/C)ccc1OCc2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L18 compound treatment 1344540.0 264000.0 1.29 1221350.0 186000.0 1.11 1414330.0 375482.58064516 2.15057363493035 2.6239 0.9576 1051539 Maybridge1_002196 CC(C)(C(=O)O)C(C)(C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L19 compound treatment 1327320.0 246000.0 1.2 1254720.0 219000.0 1.3 1288480.0 249632.58064516 1.42976871372482 2.2738 0.9975 1185814 Maybridge1_002197 Cn1c(=O)c(c(O)c2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L20 compound treatment 1143220.0 62200.0 0.3 1248850.0 214000.0 1.27 1100720.0 61872.5806451601 0.354374736724017 1.1134 0.8228 2070737 Maybridge1_002198 O=C1COc2ccccc2C(=O)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L21 compound treatment 848120.0 -233000.0 -1.14 769700.0 -266000.0 -1.58 821700.0 -217147.41935484 -1.24371019863369 -2.2867 -0.99 1340494 Maybridge1_002199 COc1ccc(OCC(O)CN)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L22 compound treatment 956640.0 -124000.0 -0.61 988250.0 -47000.0 -0.28 1003050.0 -35797.4193548399 -0.205029448052656 -0.6306 -0.9015 1100237 Maybridge1_002200 OC(=O)CC1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L23 mock treatment 1036640.0 -44300.0 -0.22 1189170.0 154000.0 0.92 1015630.0 -23217.4193548399 -0.132977593394209 0.3265 0.3438 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 L24 mock treatment 1213450.0 132000.0 0.65 943650.0 -91600.0 -0.54 1234400.0 195552.58064516 1.12002592358739 0.7058 0.5028 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M01 compound treatment 1036770.0 -44200.0 -0.22 1045880.0 10600.0 0.06 919010.0 -119837.41935484 -0.686367911128643 -0.4846 -0.6709 1623886 Maybridge1_002201 CC1(C)C(Oc2ccc(O)cc21)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M02 compound treatment 1011550.0 -69400.0 -0.34 988930.0 -46300.0 -0.28 921400.0 -117447.41935484 -0.672679204242022 -0.7433 -0.9266 2070738 Maybridge1_002202 CC(=O)c1ccc(OCc2ccc(F)cc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M03 compound treatment 1013500.0 -67500.0 -0.33 1320910.0 286000.0 1.7 950270.0 -88577.4193548399 -0.507326498042549 0.4974 0.2759 2070739 Maybridge1_002203 CC(=O)CNC(=O)Cc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M04 compound treatment 816030.0 -265000.0 -1.29 703530.0 -332000.0 -1.97 721130.0 -317717.41935484 -1.81972411143179 -2.937 -0.9856 1013471 Maybridge1_002204 CC(C)(C)C1=CC(=O)C=C(C1=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M05 compound treatment 1017600.0 -63400.0 -0.31 1129720.0 94400.0 0.56 946040.0 -92807.4193548399 -0.531553790984141 -0.1614 -0.1938 1061166 Maybridge1_002205 Cc1ccc(cc1)S(=O)(=O)NCC(=O)OCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M06 compound treatment 1332230.0 251000.0 1.23 1316490.0 281000.0 1.67 1308960.0 270112.58064516 1.54706775851059 2.5674 0.9921 2070740 Maybridge1_002206 O/N=C/1\C(=O)Nc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M07 compound treatment 964870.0 -116000.0 -0.57 736830.0 -298000.0 -1.77 856330.0 -182517.41935484 -1.04536713608822 -1.9557 -0.9154 2070741 Maybridge1_002207 COc1c2CCCc2c(C)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M08 compound treatment 1006150.0 -74800.0 -0.37 881200.0 -154000.0 -0.92 941530.0 -97317.4193548399 -0.557384781803664 -1.0619 -0.9372 1068351 Maybridge1_002208 CC(=O)c1c(C)cc2cc(C)cc(O)c2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M09 compound treatment 1226270.0 145000.0 0.71 1082420.0 47100.0 0.28 1075370.0 36522.5806451601 0.209182803847098 0.6925 0.875 2070742 Maybridge1_002209 CC(C)(C)c1ccc(cc1)C(=O)NCCSC(=O)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M10 compound treatment 1126400.0 45400.0 0.22 1206590.0 171000.0 1.02 1115330.0 76482.5806451601 0.43805340099746 0.9692 0.857 1413315 Maybridge1_002210 CCOC(=O)c1c(O)c(O)c(C(=O)OCC)n1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M11 compound treatment 890730.0 -190000.0 -0.93 870350.0 -165000.0 -0.98 776440.0 -262407.41935484 -1.50293650561631 -1.9706 -0.975 2070743 Maybridge1_002211 CC(C)(C)c1ccc(Oc2ncccc2[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M12 compound treatment 1205850.0 125000.0 0.61 1165140.0 130000.0 0.77 1141570.0 102722.58064516 0.588342802129229 1.1378 0.9923 2070744 Maybridge1_002212 COc1ccc(OC)c2c(=O)cc([nH]c12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M13 compound treatment 1274970.0 194000.0 0.95 1274290.0 239000.0 1.42 1154330.0 115482.58064516 0.661425605423489 1.7497 0.9551 2070745 Maybridge1_002213 CCCCCOc1ccc(cc1)c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M14 compound treatment 1283700.0 203000.0 0.99 1302090.0 267000.0 1.59 1250750.0 211902.58064516 1.21367042467369 2.1886 0.9816 1087097 Maybridge1_002214 OC(=O)C1CC(=O)c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M15 compound treatment 99720.0 -981000.0 -4.79 96830.0 -938000.0 -5.58 104400.0 -934447.41935484 -5.35204051234627 -9.0799 -0.998 1572932 Maybridge1_002215 Cc1cc(c2ccccc2n1)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M16 compound treatment 1152590.0 71600.0 0.35 1269610.0 234000.0 1.39 1210900.0 172052.58064516 0.985429851689655 1.5755 0.9043 1623580 Maybridge1_002216 CCCc1c(O)ccc2c(=O)cc(sc12)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M17 compound treatment 1020340.0 -60600.0 -0.3 1023710.0 -11600.0 -0.07 917500.0 -121347.41935484 -0.695016424684625 -0.612 -0.8067 1068971 Maybridge1_002217 [O-][N+](=O)c1ccc(cc1)C(=O)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M18 compound treatment 904740.0 -176000.0 -0.86 984820.0 -50500.0 -0.3 897660.0 -141187.41935484 -0.808649874320841 -1.1372 -0.9331 2070746 Maybridge1_002218 Clc1ccc(cc1)C(=S)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M19 compound treatment 1213070.0 132000.0 0.65 986770.0 -48500.0 -0.29 973340.0 -65507.4193548399 -0.375193247885921 -0.0105 -0.0132 2070747 Maybridge1_002219 CC(=O)CCn1cc(nc1C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M20 compound treatment 1139310.0 58300.0 0.29 1089300.0 54000.0 0.32 988330.0 -50517.4193548399 -0.289338136492429 0.183 0.3533 3063067 Maybridge1_002220 CS/C(=N/C(C)C)/NC(C)C.Cc1ccc(cc1)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M21 compound treatment 1103720.0 22700.0 0.11 1183630.0 148000.0 0.88 1144570.0 105722.58064516 0.60552527939277 0.9231 0.8581 2070748 Maybridge1_002221 CCOC(=O)C(C(NC(=N)S)c1ccsc1)C(=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M22 compound treatment 1274100.0 193000.0 0.94 1156480.0 121000.0 0.72 1270680.0 231832.58064516 1.32781934862781 1.7275 0.9698 1013118 Maybridge1_002222 Clc1cccc2C(=O)c3c(Cl)cccc3C(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M23 mock treatment 1019040.0 -61900.0 -0.3 1012870.0 -22400.0 -0.13 957610.0 -81237.4193548399 -0.465286703671086 -0.5203 -0.9115 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 M24 mock treatment 1222830.0 142000.0 0.69 926610.0 -109000.0 -0.65 1138800.0 99952.5806451601 0.57247764812256 0.3576 0.323 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N01 compound treatment 1054850.0 -26100.0 -0.13 1164380.0 129000.0 0.77 1101540.0 62692.5806451601 0.359071280509385 0.5769 0.673 2070749 Maybridge1_002223 CCCCCCCCOc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N02 compound treatment 1318930.0 238000.0 1.16 1161560.0 126000.0 0.75 1244650.0 205802.58064516 1.17873272090449 1.7853 0.9821 1558428 Maybridge1_002224 OCCn1c(=O)c2cc3c(=O)n(CCO)c(=O)c3cc2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N03 compound treatment 1403320.0 322000.0 1.57 1233820.0 199000.0 1.18 1291360.0 252512.58064516 1.44626389189782 2.4259 0.9932 1577930 Maybridge1_002225 CCNc1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N04 compound treatment 1274810.0 194000.0 0.95 1278790.0 244000.0 1.45 1257840.0 218992.58064516 1.25427834593986 2.107 0.9859 1031309 Maybridge1_002226 [O-][N+](=O)c1ccc2oc(=O)ccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N05 compound treatment 1229540.0 149000.0 0.73 1196240.0 161000.0 0.96 1224710.0 185862.58064516 1.06452652202615 1.5863 0.9883 2070750 Maybridge1_002227 CN1CCN(CC1)/C=N/c2ncc(cc2Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N06 compound treatment 1076800.0 -4180.0 -0.02 990560.0 -44700.0 -0.27 1034160.0 -4687.41935483995 -0.0268471588297393 -0.1808 -0.6745 2070751 Maybridge1_002228 Clc1ccc(Cl)c(OCCOc2cc(Cl)ccc2Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N07 compound treatment 929190.0 -152000.0 -0.74 974090.0 -61200.0 -0.36 928880.0 -109967.41935484 -0.629837560931594 -1.0019 -0.9645 1223178 Maybridge1_002229 O=C(c1ccccc1)c2ccc3OCCCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N08 compound treatment 888600.0 -192000.0 -0.94 801480.0 -234000.0 -1.39 668960.0 -369887.41935484 -2.11852739104476 -2.5685 -0.9503 1045283 Maybridge1_002230 CCCCC(=O)c1ccc(Br)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N09 compound treatment 1195250.0 114000.0 0.56 1051840.0 16600.0 0.1 1072130.0 33282.5806451601 0.190625728402474 0.4893 0.818 2070752 Maybridge1_002231 Cc1ccc(cc1)S(=O)(=O)N/N=C/C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N10 compound treatment 1056520.0 -24500.0 -0.12 995040.0 -40200.0 -0.24 912390.0 -126457.41935484 -0.724283910956856 -0.6253 -0.8099 1022399 Maybridge1_002232 N#CCCC1(CCC#N)c2ccccc2-c3ccccc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N11 compound treatment 1178370.0 97400.0 0.48 1139120.0 104000.0 0.62 1134610.0 95762.5806451601 0.548479454877815 0.9479 0.9945 2070753 Maybridge1_002233 COC(=O)c1cccc2cccc(c3cccc4cccc(C(=O)OC)c34)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N12 compound treatment 1052200.0 -28800.0 -0.14 991200.0 -44100.0 -0.26 975720.0 -63127.4193548399 -0.361561815923512 -0.4413 -0.9425 2070754 Maybridge1_002234 O=C1CCc2cccc3cccc1c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N13 compound treatment 844880.0 -236000.0 -1.15 885760.0 -150000.0 -0.89 812130.0 -226717.41935484 -1.29852230110439 -1.929 -0.9886 2070755 Maybridge1_002235 c1cc(c(s1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N14 compound treatment 912180.0 -169000.0 -0.82 1025300.0 -9980.0 -0.06 1035280.0 -3567.41935483995 -0.0204323673180175 -0.5222 -0.6314 2070756 Maybridge1_002236 Brc1cc2OCCOc2cc1C(=O)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N15 compound treatment 1055860.0 -25100.0 -0.12 828480.0 -207000.0 -1.23 969230.0 -69617.4193548399 -0.398733241736972 -1.011 -0.7786 1011927 Maybridge1_002237 Ic1ccc-2c(Cc3ccccc32)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N16 compound treatment 753520.0 -327000.0 -1.6 720740.0 -315000.0 -1.87 772190.0 -266657.41935484 -1.52727834840632 -2.8854 -0.9961 1657689 Maybridge1_002238 COc1ccccc1C(=O)c2cc3OCCOc3cc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N17 compound treatment 1147750.0 66800.0 0.33 1170880.0 136000.0 0.81 1140040.0 101192.58064516 0.579579738724824 0.9885 0.9457 2070757 Maybridge1_002239 CCOC(=O)COc1ccccc1C(O)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N18 compound treatment 1192390.0 111000.0 0.54 980260.0 -55000.0 -0.33 1075130.0 36282.5806451601 0.207808205666015 0.2454 0.3672 1488255 Maybridge1_002240 CC1(CC2CC3(C)C1)CC(C2)(C3)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N19 compound treatment 868000.0 -213000.0 -1.04 934750.0 -101000.0 -0.6 737150.0 -301697.41935484 -1.72796968284448 -1.9436 -0.9238 1611622 Maybridge1_002241 O=C1N(C(=O)c2cccc3cccc1c23)c4nc5ccccc5[nH]4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N20 compound treatment 1280840.0 200000.0 0.98 1219140.0 184000.0 1.09 1204990.0 166142.58064516 0.95158037148048 1.7444 0.9981 1323508 Maybridge1_002242 CCC1Oc2ccccc2C(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N21 compound treatment 1220900.0 140000.0 0.68 1269150.0 234000.0 1.39 1093280.0 54432.5806451601 0.311762193110436 1.3776 0.8715 1675924 Maybridge1_002243 Cc1c(NC(=O)CCC(=O)O)c(=O)n(c2ccccc2)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N22 compound treatment 1056290.0 -24700.0 -0.12 1139330.0 104000.0 0.62 1072230.0 33382.5806451601 0.191198477644592 0.398 0.6042 2070758 Maybridge1_002244 CC1CN=C(Nc2ccccc2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N23 mock treatment 1228640.0 148000.0 0.72 1065010.0 29700.0 0.18 1246880.0 208032.58064516 1.19150502900372 1.2065 0.8593 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 N24 mock treatment 1104930.0 24000.0 0.12 1023970.0 -11300.0 -0.07 980590.0 -58257.4193548399 -0.333668927832364 -0.1639 -0.4554 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O01 compound treatment 900240.0 -181000.0 -0.88 892110.0 -143000.0 -0.85 908250.0 -130597.41935484 -0.747995729580542 -1.4332 -0.9976 2070759 Maybridge1_002245 COC(=O)CC1C(=O)NC(=C1C(=O)OC)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O02 compound treatment 1204550.0 124000.0 0.6 1244910.0 210000.0 1.25 1129810.0 90962.5806451601 0.52098749125615 1.3691 0.9252 2070760 Maybridge1_002246 CC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O03 compound treatment 1162610.0 81600.0 0.4 1093360.0 58100.0 0.35 1065140.0 26292.5806451601 0.150590556378424 0.5166 0.9416 1505833 Maybridge1_002247 COC(=O)C1=C(C)NC(=O)C1CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O04 compound treatment 1281650.0 201000.0 0.98 1249860.0 215000.0 1.28 1201540.0 162692.58064516 0.931820522627408 1.8408 0.9899 2070761 Maybridge1_002248 COc1ccc(CO)c(Cl)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O05 compound treatment 1206720.0 126000.0 0.61 1182750.0 147000.0 0.88 1122560.0 83712.5806451601 0.479463171202593 1.1378 0.9699 2070762 Maybridge1_002249 CC1=C(C(=O)NC1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O06 compound treatment 1047520.0 -33500.0 -0.16 894470.0 -141000.0 -0.84 1000900.0 -37947.4193548399 -0.217343556758194 -0.7033 -0.7988 2070763 Maybridge1_002250 ON=C(c1cccs1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O07 compound treatment 1099430.0 18500.0 0.09 1064160.0 28900.0 0.17 1063970.0 25122.5806451601 0.143889390245643 0.2343 0.9701 2070764 Maybridge1_002251 Cc1ccc(Oc2ncccc2[N+](=O)[O-])c3CCCc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O08 compound treatment 1068160.0 -12800.0 -0.06 1171930.0 137000.0 0.81 1020550.0 -18297.4193548399 -0.104798330682002 0.3725 0.4533 2070765 Maybridge1_002252 CCCc1c(cc(cc1[N+](=O)[O-])C(=O)O)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O09 compound treatment 991050.0 -89900.0 -0.44 1018250.0 -17000.0 -0.1 997950.0 -40897.4193548399 -0.234239659400676 -0.4474 -0.8805 2070766 Maybridge1_002253 CC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O10 compound treatment 1281320.0 200000.0 0.98 1169940.0 135000.0 0.8 1219270.0 180422.58064516 1.03336896325493 1.6241 0.9944 1601320 Maybridge1_002254 CCCc1cc(=O)c2ccc(O)cc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O11 compound treatment 1283950.0 203000.0 0.99 1227680.0 192000.0 1.14 1200000.0 161152.58064516 0.92300018429879 1.766 0.9959 2070767 Maybridge1_002255 Oc1ncc(cc1Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O12 compound treatment 1113080.0 32100.0 0.16 993130.0 -42100.0 -0.25 1057670.0 18822.5806451601 0.107806187992208 0.0081 0.0257 2070768 Maybridge1_002256 CC/C(=N\NS(=O)(=O)c1ccc(C)cc1)/c2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O13 compound treatment 1071440.0 -9540.0 -0.05 1099200.0 63900.0 0.38 992520.0 -46327.4193548399 -0.265339943247684 0.0394 0.0845 2070769 Maybridge1_002257 N#CCCOc1ccc2ccccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O14 compound treatment 1115600.0 34600.0 0.17 1149500.0 114000.0 0.68 983330.0 -55517.4193548399 -0.317975598598331 0.3062 0.3983 1495792 Maybridge1_002258 Clc1ccc(cc1)N2CCC(=O)N2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O15 compound treatment 1273770.0 193000.0 0.94 988530.0 -46700.0 -0.28 1185930.0 147082.58064516 0.842414365932785 0.8697 0.6722 1400259 Maybridge1_002259 COc1cc(OC)nc(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O16 compound treatment 1193250.0 112000.0 0.55 1042330.0 7050.0 0.04 1135220.0 96372.5806451601 0.551973225254735 0.6596 0.8464 2070770 Maybridge1_002260 CC(=O)c1c(OCC=C)cc(OCc2ccccc2)c(C(=O)C)c1OCc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O17 compound treatment 1094400.0 13400.0 0.07 1086530.0 51300.0 0.3 1018170.0 -20677.4193548399 -0.118429762644411 0.1455 0.4362 2070771 Maybridge1_002261 CN(C)/C=N/c1noc(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O18 compound treatment 1115590.0 34600.0 0.17 1272070.0 237000.0 1.41 1094670.0 55822.5806451601 0.319723407575877 1.0952 0.7533 1420016 Maybridge1_002262 S=C(N1CCOCC1)c2ccc(C#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O19 compound treatment 1024030.0 -56900.0 -0.28 1115320.0 80000.0 0.48 916970.0 -121877.41935484 -0.698051995667851 -0.2889 -0.3247 1175684 Maybridge1_002263 OC(=O)CCC1CCCCCCCCCCC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O20 compound treatment 1185690.0 105000.0 0.51 950960.0 -84300.0 -0.5 998670.0 -40177.4193548399 -0.230115864857426 -0.127 -0.1687 2070772 Maybridge1_002264 CCN(C(=N)SC)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O21 compound treatment 999690.0 -81300.0 -0.4 1139040.0 104000.0 0.62 968080.0 -70767.4193548399 -0.405319858021329 -0.1071 -0.1277 2070773 Maybridge1_002265 CCCCCCCCc1ccc(cc1)C(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O22 compound treatment 1245880.0 165000.0 0.81 1151480.0 116000.0 0.69 1144320.0 105472.58064516 0.604093406287475 1.2129 0.9931 1036785 Maybridge1_002266 OC(=O)c1ccc(Cl)cc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O23 mock treatment 1348710.0 268000.0 1.31 1224220.0 189000.0 1.12 1207720.0 168872.58064516 0.967216425790302 1.9623 0.9925 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 O24 mock treatment 964830.0 -116000.0 -0.57 965190.0 -70100.0 -0.42 984670.0 -54177.4193548399 -0.310300758753949 -0.7474 -0.9714 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P01 compound treatment 1052530.0 -28400.0 -0.14 1122260.0 87000.0 0.52 1070100.0 31252.5806451601 0.178998918787478 0.3217 0.5697 2070774 Maybridge1_002267 CSc1ncc(Cl)c(n1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P02 compound treatment 1060170.0 -20800.0 -0.1 971810.0 -63500.0 -0.38 947080.0 -91767.4193548399 -0.525597198866114 -0.58 -0.8856 2070775 Maybridge1_002268 CC(=O)C1C(CC(=CC1=O)/C=C/c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P03 compound treatment 173760.0 -907000.0 -4.43 155360.0 -880000.0 -5.23 154640.0 -884207.41935484 -5.06429129310618 -8.504 -0.9975 2070776 Maybridge1_002269 CN(C)c1ccc(/C=C/c2ccc3ccccc3[n+]2C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P04 compound treatment 742110.0 -339000.0 -1.66 780900.0 -254000.0 -1.51 851870.0 -186977.41935484 -1.07091175228668 -2.4475 -0.9848 1237161 Maybridge1_002270 OC(COc1ccccc1)CN2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P05 compound treatment 1176320.0 95300.0 0.47 1068450.0 33200.0 0.2 1119870.0 81022.5806451601 0.464056216589618 0.6508 0.948 2070777 Maybridge1_002271 FC(F)(F)c1cnc(/N=C/N2CCCCC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P06 compound treatment 1138080.0 57100.0 0.28 1250080.0 215000.0 1.28 1172870.0 134022.58064516 0.767613314912171 1.3417 0.885 1026005 Maybridge1_002272 C(COc1cccc2ccccc12)Oc3cccc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P07 compound treatment 1261610.0 181000.0 0.88 1227250.0 192000.0 1.14 1212110.0 173262.58064516 0.992360117519283 1.7416 0.9945 1023158 Maybridge1_002273 Cc1cc(O)n2ncnc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P08 compound treatment 1243240.0 162000.0 0.79 1203810.0 169000.0 1.0 1111970.0 73122.5806451601 0.418809026462295 1.2781 0.9505 1022119 Maybridge1_002274 OC(=O)c1cc(Br)c(Br)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P09 compound treatment 1089300.0 8320.0 0.04 1208810.0 174000.0 1.03 1097440.0 58592.5806451601 0.335588561582546 0.813 0.7487 1250550 Maybridge1_002275 OC(=O)C1Cc2ccccc2-c3ccccc3C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P10 compound treatment 958980.0 -122000.0 -0.6 923370.0 -112000.0 -0.67 897630.0 -141217.41935484 -0.808821699093476 -1.1953 -0.9919 1028547 Maybridge1_002276 Cc1ccc(C)n1CCn2c(C)ccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P11 compound treatment 1210490.0 130000.0 0.63 1182440.0 147000.0 0.88 1134820.0 95972.5806451601 0.549682228286263 1.1879 0.9803 1009725 Maybridge1_002277 OC(=O)c1cccc2cccc(c3cccc4cccc(C(=O)O)c34)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P12 compound treatment 31790.0 -1050000.0 -5.13 27130.0 -1010000.0 -6.0 28000.0 -1010847.41935484 -5.78962093332444 -9.7634 -0.9978 1305565 Maybridge1_002278 OC(COc1ccc(cc1)C2(CC3CC4CC(C3)C2)C4)CN5CCCCC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P13 compound treatment 1090510.0 9530.0 0.05 1050980.0 15700.0 0.09 1023580.0 -15267.4193548399 -0.0874440286458262 0.0303 0.2227 1030892 Maybridge1_002279 Cc1cc(=O)oc2cc(N)ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P14 compound treatment 1130150.0 49200.0 0.24 1253190.0 218000.0 1.3 1134300.0 95452.5806451601 0.546703932227249 1.2025 0.8428 1414498 Maybridge1_002280 Brc1cc2OCCCOc2cc1C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P15 compound treatment 980650.0 -100000.0 -0.49 1060290.0 25000.0 0.15 938480.0 -100367.41935484 -0.574853633688264 -0.529 -0.6871 1067594 Maybridge1_002281 CC(=O)c1ccc-2c(Cc3cc(ccc32)C(=O)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P16 compound treatment 919690.0 -161000.0 -0.79 1043250.0 7970.0 0.05 1008870.0 -29977.4193548399 -0.171695442161387 -0.5267 -0.652 1371529 Maybridge1_002282 Cc1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P17 compound treatment 103050.0 -978000.0 -4.78 68640.0 -967000.0 -5.75 102790.0 -936057.41935484 -5.36126177514437 -9.1726 -0.9972 2070778 Maybridge1_002283 CC(=O)Nc1cccc([N+](=O)[O-])c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P18 compound treatment 1164130.0 83200.0 0.41 1000030.0 -35200.0 -0.21 1148160.0 109312.58064516 0.626086977184807 0.475 0.6127 1172246 Maybridge1_002284 OC(=O)CCC1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P19 compound treatment 929570.0 -151000.0 -0.74 932570.0 -103000.0 -0.61 891420.0 -147427.41935484 -0.844389427029006 -1.2672 -0.9916 1366365 Maybridge1_002285 CN(C)c1ccc2C(=O)N(C(=O)c3cccc1c32)c4nc5ccccc5[nH]4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P20 compound treatment 1149120.0 68100.0 0.33 1143460.0 108000.0 0.64 1077950.0 39102.5806451601 0.223959734293743 0.6929 0.9139 1503386 Maybridge1_002286 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CC(=O)NC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P21 compound treatment 1193780.0 113000.0 0.55 1121520.0 86200.0 0.51 1125860.0 87012.5806451601 0.498363896192488 0.902 0.9991 1467705 Maybridge1_002287 Cc1ccc(NC(=O)CCC(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P22 compound treatment 917240.0 -164000.0 -0.8 858560.0 -177000.0 -1.05 944800.0 -94047.4193548399 -0.538655881586405 -1.3796 -0.9672 2070779 Maybridge1_002288 CC1CN=C(Nc2ccc(C)cc2)S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P23 mock treatment 1153280.0 72300.0 0.35 1172280.0 137000.0 0.81 1159570.0 120722.58064516 0.691437665710474 1.0735 0.9539 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.547 P24 mock treatment 963260.0 -118000.0 -0.58 979320.0 -56000.0 -0.33 990650.0 -48197.4193548399 -0.276050354075291 -0.6836 -0.95 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A01 compound treatment 926680.0 -151000.0 -0.74 782090.0 -273000.0 -1.62 800330.0 -160619.375 -0.919946253007206 -1.8936 -0.9444 2070780 Maybridge1_002993 CC(C)(C)SCCNC(=O)c1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A02 compound treatment 878560.0 -199000.0 -0.97 800640.0 -254000.0 -1.51 862560.0 -98389.375 -0.56352439963716 -1.7599 -0.9342 2070781 Maybridge1_002994 CS/C(=N/C#N)/NCCSCc1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A03 compound treatment 975060.0 -103000.0 -0.5 877210.0 -178000.0 -1.06 864820.0 -96129.375 -0.550580266765292 -1.2173 -0.942 1677090 Maybridge1_002995 Clc1ccc(Oc2ccccc2S(=O)(=O)Nc3cc(Cl)cc(Cl)c3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A04 compound treatment 799010.0 -279000.0 -1.36 801940.0 -253000.0 -1.5 740510.0 -220439.375 -1.26256484964221 -2.3834 -0.9974 2070782 Maybridge1_002996 Cc1nc(C)c(s1)c2ccn(n2)C(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A05 compound treatment 729890.0 -348000.0 -1.7 638720.0 -416000.0 -2.47 629520.0 -331429.375 -1.898259233469 -3.5058 -0.9871 2070783 Maybridge1_002997 [O-][N+](=O)c1ccc(Sc2nnc(S)s2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A06 compound treatment 969710.0 -108000.0 -0.53 848830.0 -206000.0 -1.22 842980.0 -117969.375 -0.675668701243869 -1.4021 -0.9378 2070784 Maybridge1_002998 CC(=O)c1nnn(c1C)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A07 compound treatment 886240.0 -192000.0 -0.94 824560.0 -230000.0 -1.37 733920.0 -227029.375 -1.30030902469778 -2.0815 -0.9877 2070785 Maybridge1_002999 Cc1onc(c1C(=O)c2ccccc2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A08 compound treatment 928330.0 -150000.0 -0.73 880560.0 -174000.0 -1.04 842640.0 -118309.375 -0.67761604866707 -1.411 -0.9817 2070786 Maybridge1_003000 CS/C(=N\C#N)/N1CCN(CC1)c2ccc(cn2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A09 compound treatment 753090.0 -325000.0 -1.59 682030.0 -373000.0 -2.22 706210.0 -254739.375 -1.45901783968869 -3.0381 -0.9827 1267859 Maybridge1_003001 Cc1onc(c1C(O)c2ccc(F)cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A10 compound treatment 1023360.0 -54500.0 -0.27 943170.0 -112000.0 -0.66 841090.0 -119859.375 -0.686493661919899 -0.9331 -0.9414 1463907 Maybridge1_003002 O=C(NC1CCCCNC1=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A11 compound treatment 404580.0 -673000.0 -3.29 399460.0 -655000.0 -3.9 348320.0 -612629.375 -3.50883010230488 -6.1747 -0.9975 2070787 Maybridge1_003003 CC1(C)OC(=O)C(=Cc2cc(Br)cs2)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A12 compound treatment 903260.0 -175000.0 -0.85 840480.0 -214000.0 -1.27 737020.0 -223929.375 -1.28255379819213 -1.9686 -0.9848 2070788 Maybridge1_003004 CS/C(=N\C#N)/N1CCC(CC1)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A13 compound treatment 25660.0 -1050000.0 -5.14 24180.0 -1030000.0 -6.13 33280.0 -927669.375 -5.3132193146735 -9.5738 -0.997 2070789 Maybridge1_003005 CC1(C)C(=C(Br)C(=O)C1(Br)Br)Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A14 compound treatment 698810.0 -379000.0 -1.85 598340.0 -456000.0 -2.71 572270.0 -388679.375 -2.22615817458157 -3.9214 -0.9881 1086555 Maybridge1_003006 COc1ccc(OC)c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A15 compound treatment 893170.0 -185000.0 -0.9 843620.0 -211000.0 -1.26 692240.0 -268709.375 -1.53903090881258 -2.1343 -0.9784 2070790 Maybridge1_003007 Cc1nn(cc1c2ccccc2)C(=O)Nc3c(C)onc3c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A16 compound treatment 892430.0 -185000.0 -0.91 872560.0 -182000.0 -1.08 829360.0 -131589.375 -0.753677148020344 -1.5836 -0.9893 2070791 Maybridge1_003008 CS/C(=N/C#N)/NCC#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A17 compound treatment 923200.0 -155000.0 -0.76 891790.0 -163000.0 -0.97 827000.0 -133949.375 -0.767194030134329 -1.4386 -0.9931 1691204 Maybridge1_003009 CNn1cnc2ccccc2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A18 compound treatment 228590.0 -849000.0 -4.15 228640.0 -826000.0 -4.91 164480.0 -796469.375 -4.56177230901466 -7.8656 -0.9976 2070792 Maybridge1_003010 FC(F)(F)c1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A19 compound treatment 1019740.0 -58100.0 -0.28 902180.0 -153000.0 -0.91 823530.0 -137419.375 -0.787068428835824 -1.1421 -0.9254 1195410 Maybridge1_003011 Clc1cccc(Cl)c1COc2cccc(c2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A20 compound treatment 861540.0 -216000.0 -1.06 923960.0 -131000.0 -0.78 816960.0 -143989.375 -0.824698054042978 -1.5353 -0.9907 1225869 Maybridge1_003012 CC(C)(CO)NC(=O)c1cccc(C(=O)NC(C)(C)CO)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A21 compound treatment 560100.0 -518000.0 -2.53 502340.0 -552000.0 -3.28 494340.0 -466609.375 -2.67250165896415 -4.9 -0.9934 2070793 Maybridge1_003013 O/N=C/N/C(=N\OCc1c(F)cccc1Cl)/c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A22 compound treatment 887560.0 -190000.0 -0.93 849360.0 -205000.0 -1.22 744160.0 -216789.375 -1.2416595023049 -1.9588 -0.9922 1355108 Maybridge1_003014 CCNS(=O)(=O)c1cc(Cl)sc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A23 mock treatment 960320.0 -118000.0 -0.57 942930.0 -112000.0 -0.66 873840.0 -87109.375 -0.498918285126247 -1.0034 -0.9932 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 A24 mock treatment 954530.0 -123000.0 -0.6 818880.0 -236000.0 -1.4 860740.0 -100209.375 -0.573948435843708 -1.489 -0.913 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B01 compound treatment 929510.0 -148000.0 -0.72 907540.0 -147000.0 -0.88 878330.0 -82619.375 -0.473201844155148 -1.197 -0.9724 2070794 Maybridge1_003015 Cc1ccc(cc1)C2CC(=O)CC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B02 compound treatment 860180.0 -218000.0 -1.06 796730.0 -258000.0 -1.53 827110.0 -133839.375 -0.766564005967999 -1.9424 -0.9625 2070795 Maybridge1_003016 CC(C)c1ccc(/C=N/NC(=O)CC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B03 compound treatment 986430.0 -91400.0 -0.45 881490.0 -173000.0 -1.03 856190.0 -104759.375 -0.600008526360078 -1.1991 -0.9418 2070796 Maybridge1_003017 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)S(=O)(=O)NCc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B04 compound treatment 891900.0 -186000.0 -0.91 867150.0 -188000.0 -1.12 849620.0 -111329.375 -0.637638151567232 -1.5367 -0.9765 2070797 Maybridge1_003018 COc1cc([N+](=O)[O-])c2NC(CC(c3ccccc3)c2c1)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B05 compound treatment 890360.0 -187000.0 -0.92 775960.0 -279000.0 -1.66 748500.0 -212449.375 -1.21680218519698 -2.1885 -0.9721 1469336 Maybridge1_003019 Cn1nccc1c2ccc(Oc3cccc(Cl)c3C#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B06 compound treatment 706760.0 -371000.0 -1.81 653400.0 -401000.0 -2.39 621390.0 -339559.375 -1.9448237468532 -3.5475 -0.9929 1005561 Maybridge1_003020 Cc1cccc(NC(=O)c2ccccc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B07 compound treatment 901940.0 -176000.0 -0.86 851710.0 -203000.0 -1.21 851730.0 -109219.375 -0.625553142558542 -1.5544 -0.9663 2070798 Maybridge1_003021 CC1=C(C#N)S(=O)(=O)C(C#N)C(C1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B08 compound treatment 892040.0 -186000.0 -0.91 917970.0 -137000.0 -0.81 791700.0 -169249.375 -0.969374512601991 -1.5534 -0.9974 1083105 Maybridge1_003022 O=C(CC#N)NCc1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B09 compound treatment 659680.0 -418000.0 -2.04 613380.0 -441000.0 -2.62 567490.0 -393459.375 -2.25353558835481 -3.996 -0.9946 2070799 Maybridge1_003023 CC(=O)c1ccc(o1)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B10 compound treatment 993410.0 -84400.0 -0.41 875770.0 -179000.0 -1.06 798880.0 -162069.375 -0.928251117017917 -1.3886 -0.9438 1083112 Maybridge1_003024 Cc1ccc(cc1C)C(=O)c2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B11 compound treatment 914790.0 -163000.0 -0.8 893600.0 -161000.0 -0.96 761290.0 -199659.375 -1.14354755713008 -1.6734 -0.9894 1717233 Maybridge1_003025 COc1cccc(OC)c1C(=O)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B12 compound treatment 952250.0 -126000.0 -0.61 1056960.0 2220.0 0.01 958140.0 -2809.375 -0.0160906740207532 -0.356 -0.5798 2070800 Maybridge1_003026 Cc1ccc(cc1)c2nc3cc(C)c(C)cc3nc2c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B13 compound treatment 1008660.0 -69200.0 -0.34 971280.0 -83500.0 -0.5 876840.0 -84109.375 -0.481735807862706 -0.7598 -0.987 1210739 Maybridge1_003027 CC1(C)OC(=O)C(=C2CCCN2)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B14 compound treatment 891100.0 -187000.0 -0.91 861120.0 -194000.0 -1.15 824030.0 -136919.375 -0.784204682625234 -1.6443 -0.9874 1571466 Maybridge1_003028 Clc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B15 compound treatment 774010.0 -304000.0 -1.48 840100.0 -215000.0 -1.28 720000.0 -240949.375 -1.38003571920061 -2.3907 -0.9981 2070801 Maybridge1_003029 [O-][N+](=O)c1cc(/C=N/N2CCOCC2)cs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B16 compound treatment 836720.0 -241000.0 -1.18 860090.0 -195000.0 -1.16 783300.0 -177649.375 -1.01748544893991 -1.9359 -0.998 2070802 Maybridge1_003030 CC(C)(NC(=O)Nc1ccccc1)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B17 compound treatment 973820.0 -104000.0 -0.51 967860.0 -86900.0 -0.52 816600.0 -144349.375 -0.826759951314603 -1.069 -0.9724 1384934 Maybridge1_003031 Cc1cc(SCCS(=O)(=O)CCSc2cc(C)c(Cl)cc2C)c(C)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B18 compound treatment 893380.0 -184000.0 -0.9 921150.0 -134000.0 -0.79 835840.0 -125109.375 -0.716562997131096 -1.3927 -0.9956 1244752 Maybridge1_003032 CC(C)c1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B19 compound treatment 853840.0 -224000.0 -1.09 994800.0 -59900.0 -0.36 816610.0 -144339.375 -0.826702676390392 -1.315 -0.9279 2070803 Maybridge1_003033 CC(C)NC(=O)N1CCc2sccc2C1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B20 compound treatment 472670.0 -605000.0 -2.96 447480.0 -607000.0 -3.61 393520.0 -567429.375 -3.24994744486754 -5.6683 -0.9967 1206974 Maybridge1_003034 COc1ccc(cc1)n2c(csc2=N)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B21 compound treatment 928590.0 -149000.0 -0.73 909920.0 -145000.0 -0.86 844480.0 -116469.375 -0.667077462612098 -1.3034 -0.9943 1696004 Maybridge1_003035 OC(=O)C1CN(Cc2ccco2)C(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B22 compound treatment 889390.0 -188000.0 -0.92 896810.0 -158000.0 -0.94 838510.0 -122439.375 -0.701270592366544 -1.4787 -0.9921 1406609 Maybridge1_003036 CC1CC(CC(C)(C)C1)NC(=O)c2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B23 mock treatment 1028360.0 -49500.0 -0.24 1025340.0 -29400.0 -0.17 891860.0 -69089.375 -0.395708871696579 -0.469 -0.9463 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 B24 mock treatment 944180.0 -134000.0 -0.65 938720.0 -116000.0 -0.69 881650.0 -79299.375 -0.454186569316829 -1.0376 -0.9854 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C01 compound treatment 1043370.0 -34500.0 -0.17 927580.0 -127000.0 -0.76 979600.0 18650.625 0.106821313337775 -0.4721 -0.6037 1943772 Maybridge1_003037 Clc1ccc(CSc2nsc(SCc3ccc(Cl)cc3)n2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C02 compound treatment 805870.0 -272000.0 -1.33 759160.0 -296000.0 -1.76 684380.0 -276569.375 -1.58404899924305 -2.6965 -0.9937 2070804 Maybridge1_003038 Cc1cc(OS(=O)(=O)CS(=O)(=O)Oc2ccc(Cl)c(C)c2)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C03 compound treatment 943490.0 -134000.0 -0.66 931920.0 -123000.0 -0.73 875620.0 -85329.375 -0.488723348616546 -1.0828 -0.9872 1679950 Maybridge1_003039 Clc1ccc(Oc2ccccc2S(=O)(=O)N3CCCCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C04 compound treatment 1085980.0 8140.0 0.04 946140.0 -109000.0 -0.65 876570.0 -84379.375 -0.483282230816425 -0.6289 -0.7788 2070805 Maybridge1_003040 CN(C)/C=C(\C#N)/S(=O)(=O)\C(=C\N(C)C)\C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C05 compound treatment 979220.0 -98600.0 -0.48 888700.0 -166000.0 -0.99 810110.0 -150839.375 -0.863931377128063 -1.3471 -0.9638 2070806 Maybridge1_003041 Cc1onc(c1C(=O)OCC(F)(F)F)c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C06 compound treatment 24420.0 -1050000.0 -5.15 23560.0 -1030000.0 -6.13 24800.0 -936149.375 -5.36178845040511 -9.6075 -0.9971 2070807 Maybridge1_003042 CC(=O)OCC(=O)c1cc(Cl)sc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C07 compound treatment 866080.0 -212000.0 -1.03 822630.0 -232000.0 -1.38 740980.0 -219969.375 -1.25987292820425 -2.1216 -0.9932 2070808 Maybridge1_003043 Cc1onc(c1C(=O)c2ccccc2)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C08 compound treatment 723570.0 -354000.0 -1.73 734040.0 -321000.0 -1.91 609870.0 -351079.375 -2.01080445954519 -3.2613 -0.9981 2070809 Maybridge1_003044 CC(=O)C(=NNc1c(C)nn(C)c1C)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C09 compound treatment 866520.0 -211000.0 -1.03 823730.0 -231000.0 -1.37 697180.0 -263769.375 -1.51073709625195 -2.2615 -0.9883 2070810 Maybridge1_003045 CC(=O)c1ccccc1OC(=O)c2ccc(o2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C10 compound treatment 953600.0 -124000.0 -0.61 916000.0 -139000.0 -0.83 779370.0 -181579.375 -1.03999449415514 -1.4272 -0.9778 2070811 Maybridge1_003046 CC1=C(OS(=O)(=O)c2cc(C)c(Cl)cc2Cl)C(=O)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C11 compound treatment 912010.0 -166000.0 -0.81 1026410.0 -28300.0 -0.17 869290.0 -91659.375 -0.524978375642617 -0.8682 -0.8858 2070812 Maybridge1_003047 Cc1nn(C(=O)c2c(Cl)cccc2Cl)c(C)c1Cc3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C12 compound treatment 866360.0 -211000.0 -1.03 830500.0 -224000.0 -1.33 766480.0 -194469.375 -1.11382187146416 -2.0095 -0.9941 1659368 Maybridge1_003048 Nc1nnc(SCc2c(Cl)cccc2Cl)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C13 compound treatment 1091130.0 13300.0 0.06 1207110.0 152000.0 0.91 1042450.0 81500.625 0.466794212008952 0.8301 0.8128 2070813 Maybridge1_003049 Cc1cc(NN=Nc2cc(C)on2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C14 compound treatment 862110.0 -216000.0 -1.05 916500.0 -138000.0 -0.82 846720.0 -114229.375 -0.654247879588655 -1.4609 -0.9816 2070814 Maybridge1_003050 CC(=O)c1nnn(c1C)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C15 compound treatment 919210.0 -159000.0 -0.78 936130.0 -119000.0 -0.71 805610.0 -155339.375 -0.889705093023374 -1.3684 -0.9954 2070815 Maybridge1_003051 Clc1ccc(cc1)c2noc(n2)c3c[nH]nc3c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C16 compound treatment 666570.0 -411000.0 -2.01 651860.0 -403000.0 -2.4 656270.0 -304679.375 -1.74504881120243 -3.5508 -0.9916 2070816 Maybridge1_003052 Fc1c(COC(=O)Nc2ccccc2)cccc1COC(=O)Nc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C17 compound treatment 1055400.0 -22400.0 -0.11 1128160.0 73400.0 0.44 990630.0 29680.625 0.169995554743393 0.2869 0.5963 1381264 Maybridge1_003053 CN(C(=O)Nc1ccccc1)n2cnc3ccccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C18 compound treatment 1024890.0 -53000.0 -0.26 997180.0 -57600.0 -0.34 881830.0 -79119.375 -0.453155620681017 -0.6086 -0.9753 2070817 Maybridge1_003054 CS(=O)(=O)CS(=O)(=O)Oc1cccc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C19 compound treatment 956120.0 -122000.0 -0.59 917000.0 -138000.0 -0.82 797860.0 -163089.375 -0.934093159287521 -1.3556 -0.9842 2070818 Maybridge1_003055 Clc1cc(c(Cl)s1)S(=O)(=O)NC(=N)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C20 compound treatment 776720.0 -301000.0 -1.47 752510.0 -302000.0 -1.8 587620.0 -373329.375 -2.13824116591645 -3.1216 -0.9888 2070819 Maybridge1_003056 Cn1cccc1C(=O)N/N=C/c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C21 compound treatment 712100.0 -366000.0 -1.79 673120.0 -382000.0 -2.27 603240.0 -357709.375 -2.04877773429762 -3.5248 -0.9953 2070820 Maybridge1_003057 CN(C)/C=C/c1nn(C)c(C)c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C22 compound treatment 934740.0 -143000.0 -0.7 989450.0 -65300.0 -0.39 831120.0 -129829.375 -0.743596761359066 -1.0571 -0.9681 2070821 Maybridge1_003058 CN(C)CCCN(S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C23 mock treatment 954930.0 -123000.0 -0.6 1024360.0 -30400.0 -0.18 928060.0 -32889.375 -0.188373646049855 -0.5598 -0.8549 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 C24 mock treatment 856190.0 -222000.0 -1.08 826340.0 -228000.0 -1.36 811520.0 -149429.375 -0.855855612814199 -1.9035 -0.983 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D01 compound treatment 1022090.0 -55800.0 -0.27 856980.0 -198000.0 -1.18 863150.0 -97799.375 -0.560145179108663 -1.1596 -0.8714 2070822 Maybridge1_003059 Clc1ccc(cc1Cl)C2CC(=O)CC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D02 compound treatment 1011640.0 -66200.0 -0.32 969790.0 -85000.0 -0.51 918840.0 -42109.375 -0.241181126173136 -0.6177 -0.9553 2070823 Maybridge1_003060 O=C(CC#N)NN=C1CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D03 compound treatment 1013800.0 -64000.0 -0.31 919150.0 -136000.0 -0.81 843720.0 -117229.375 -0.671430356852195 -1.0338 -0.9442 2070824 Maybridge1_003061 FC(F)(F)COc1cccc(Cl)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D04 compound treatment 1042150.0 -35700.0 -0.17 1048960.0 -5780.0 -0.03 966890.0 5940.625 0.0340248846645738 -0.1009 -0.5575 1183271 Maybridge1_003062 Clc1ccc(Cl)c(c1)S(=O)(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D05 compound treatment 762880.0 -315000.0 -1.54 698690.0 -356000.0 -2.12 661780.0 -299169.375 -1.71349032796173 -3.1002 -0.991 1686627 Maybridge1_003063 Nc1nccc(n1)c2ccc(Oc3cccc(Cl)c3C#N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D06 compound treatment 100000.0 -978000.0 -4.78 63110.0 -992000.0 -5.9 98850.0 -862099.375 -4.93766763661672 -9.0136 -0.9955 1214473 Maybridge1_003064 Cc1ccc(NC(=S)C(C#N)C(=O)Nc2ccccc2C)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D07 compound treatment 927730.0 -150000.0 -0.73 899110.0 -156000.0 -0.93 794300.0 -166649.375 -0.954483032306922 -1.5088 -0.9937 1394780 Maybridge1_003065 COc1ccc(cc1)C2CC(=C(C#N)S(=O)(=O)C2C#N)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D08 compound treatment 889840.0 -188000.0 -0.92 951200.0 -104000.0 -0.62 833870.0 -127079.375 -0.727846157200821 -1.306 -0.9865 1580315 Maybridge1_003066 Cc1ccc(NC(=S)C(C#N)C(=O)N2CCCC2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D09 compound treatment 1033040.0 -44800.0 -0.22 1045650.0 -9090.0 -0.05 799580.0 -161369.375 -0.924241872323091 -0.6912 -0.7266 2070825 Maybridge1_003067 Nc1nn(cc1C#N)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D10 compound treatment 803400.0 -274000.0 -1.34 781010.0 -274000.0 -1.63 656880.0 -304069.375 -1.74155504082551 -2.7194 -0.9943 1472381 Maybridge1_003068 Cc1ccc(cc1C)c2nn(c3ccccc3)c(=O)c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D11 compound treatment 996330.0 -81500.0 -0.4 1114930.0 60200.0 0.36 834040.0 -126909.375 -0.72687248348922 -0.443 -0.4906 1571233 Maybridge1_003069 COC(OC)C(C)(O)c1c(OC)cccc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D12 compound treatment 578100.0 -500000.0 -2.44 582560.0 -472000.0 -2.81 463840.0 -497109.375 -2.84719017781014 -4.6746 -0.9977 2070826 Maybridge1_003070 CCc1nn2cc(nc2s1)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D13 compound treatment 515160.0 -563000.0 -2.75 493350.0 -561000.0 -3.34 352330.0 -608619.375 -3.48586285769595 -5.5272 -0.9951 2070827 Maybridge1_003071 Cc1nn(C)c(O)c1N=Nc2ccc(cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D14 compound treatment 804840.0 -273000.0 -1.33 702320.0 -352000.0 -2.1 679880.0 -281069.375 -1.60982271513836 -2.9095 -0.9829 1486629 Maybridge1_003072 COc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D15 compound treatment 647680.0 -430000.0 -2.1 632250.0 -422000.0 -2.51 506660.0 -454289.375 -2.6019389523352 -4.1662 -0.9959 2070828 Maybridge1_003073 [O-][N+](=O)c1cc(/C=N/Nc2ccccn2)cs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D16 compound treatment 940600.0 -137000.0 -0.67 954610.0 -100000.0 -0.6 760040.0 -200909.375 -1.15070692265656 -1.3953 -0.9564 1162448 Maybridge1_003074 O=C1Nc2ccccc2N=C(c3ccccc3)c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D17 compound treatment 955730.0 -122000.0 -0.6 977680.0 -77100.0 -0.46 762640.0 -198309.375 -1.13581544236149 -1.2648 -0.9284 1573828 Maybridge1_003075 O=S1(=O)CCN(Cc2cccs2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D18 compound treatment 886090.0 -192000.0 -0.94 933610.0 -121000.0 -0.72 771440.0 -189509.375 -1.0854135090551 -1.5834 -0.9868 1247208 Maybridge1_003076 CC(=O)Nc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D19 compound treatment 1073190.0 -4650.0 -0.02 1204230.0 149000.0 0.89 923960.0 -36989.375 -0.211856364976694 0.3778 0.4133 2070829 Maybridge1_003077 FC(F)(F)c1cccc(/N=C/c2ccc(Cl)cc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D20 compound treatment 480690.0 -597000.0 -2.92 512400.0 -542000.0 -3.23 439230.0 -521719.375 -2.98814376629539 -5.2717 -0.9991 1698556 Maybridge1_003078 Clc1cccc(c1Cl)n2c(csc2=N)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D21 compound treatment 505400.0 -572000.0 -2.8 591310.0 -463000.0 -2.76 476220.0 -484729.375 -2.77628382163593 -4.8087 -1.0 2070830 Maybridge1_003079 FC(F)(F)c1cc(NC2=C(C(=O)c3ccccc23)c4ccccc4)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D22 compound treatment 888520.0 -189000.0 -0.92 765960.0 -289000.0 -1.72 668800.0 -292149.375 -1.67328333116504 -2.4916 -0.9695 2070831 Maybridge1_003080 Cc1ccc(CS/C(=N/N)/N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D23 mock treatment 909230.0 -169000.0 -0.82 1007540.0 -47200.0 -0.28 927600.0 -33349.375 -0.191008292563598 -0.748 -0.8394 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 D24 mock treatment 1018720.0 -59100.0 -0.29 1020640.0 -34100.0 -0.2 893140.0 -67809.375 -0.388377681397468 -0.5081 -0.9682 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E01 compound treatment 1014810.0 -63000.0 -0.31 1018190.0 -36600.0 -0.22 959640.0 -1309.375 -0.00749943538898287 -0.3076 -0.8159 2070832 Maybridge1_003081 CC(C)(C)c1csc(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E02 compound treatment 970440.0 -107000.0 -0.52 1038930.0 -15800.0 -0.09 883360.0 -77589.375 -0.444392557276611 -0.6138 -0.8844 2070833 Maybridge1_003082 Clc1ccc(cc1)C2CC(=O)CC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E03 compound treatment 842620.0 -235000.0 -1.15 810810.0 -244000.0 -1.45 674360.0 -286589.375 -1.64143847330328 -2.4487 -0.9899 2070834 Maybridge1_003083 CC(C)(C)c1csc(=S)n1CCc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E04 compound treatment 948960.0 -129000.0 -0.63 993830.0 -60900.0 -0.36 836030.0 -124919.375 -0.715474773571071 -0.9858 -0.9668 1080296 Maybridge1_003084 CC1SCC(=NO)CS1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E05 compound treatment 994350.0 -83500.0 -0.41 1035580.0 -19200.0 -0.11 819480.0 -141469.375 -0.810264773141604 -0.7691 -0.8412 2070835 Maybridge1_003085 Cc1cc(C)n(n1)C2=NCCN2C(=O)c3ccccc3F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E06 compound treatment 1139380.0 61500.0 0.3 1200980.0 146000.0 0.87 972000.0 11050.625 0.0632923709368048 0.7122 0.7722 2070836 Maybridge1_003086 CSC(=N)n1nc(SC)nc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E07 compound treatment 996320.0 -81500.0 -0.4 1015800.0 -38900.0 -0.23 736000.0 -224949.375 -1.28839584046173 -1.1075 -0.8094 1349717 Maybridge1_003087 Cc1onc(c1C(O)c2ccccc2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E08 compound treatment 1064290.0 -13600.0 -0.07 1095260.0 40500.0 0.24 897310.0 -63639.375 -0.364494038001147 -0.1096 -0.2479 1322001 Maybridge1_003088 Cc1nn(C)c(C)c1NC(=O)c2ccccc2NS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E09 compound treatment 1199720.0 122000.0 0.6 1120030.0 65300.0 0.39 860720.0 -100229.375 -0.574062985692131 0.2365 0.2588 1387444 Maybridge1_003089 Fc1ccc(cc1)C(=O)CCCC(=O)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E10 compound treatment 881360.0 -196000.0 -0.96 891590.0 -163000.0 -0.97 683090.0 -277859.375 -1.59143746446638 -2.0332 -0.9698 2070837 Maybridge1_003090 CCOC(=O)c1cnn(c1c2ccccc2)c3c(Cl)cc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E11 compound treatment 1304040.0 226000.0 1.11 1313340.0 259000.0 1.54 862880.0 -98069.375 -0.561691602062382 1.2016 0.6083 2070838 Maybridge1_003091 Cc1nn(c(C)c1Cc2c(Cl)cccc2Cl)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E12 compound treatment 793210.0 -285000.0 -1.39 726000.0 -329000.0 -1.95 568160.0 -392789.375 -2.24969816843262 -3.2304 -0.9822 2070839 Maybridge1_003092 CN(C)c1c(/C=C/2\C(=O)Nc3ccccc23)cc(\C=C/4\C(=O)Nc5ccccc45)c(N(C)C)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E13 compound treatment 716900.0 -361000.0 -1.76 732220.0 -323000.0 -1.92 801840.0 -159109.375 -0.911297739451224 -2.6516 -0.9607 1073411 Maybridge1_003093 NC1=C(C(=O)c2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E14 compound treatment 976660.0 -101000.0 -0.49 1109220.0 54500.0 0.32 816660.0 -144289.375 -0.826416301769332 -0.5755 -0.5664 2070840 Maybridge1_003094 CC(=O)c1nnn(c1C)c2cc(Cl)ccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E15 compound treatment 1087780.0 9940.0 0.05 1136400.0 81700.0 0.49 833120.0 -127829.375 -0.732141776516706 -0.1143 -0.1299 1552363 Maybridge1_003095 O=S(=O)(CS(=O)(=O)N1CCOCC1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E16 compound treatment 976890.0 -101000.0 -0.49 1051200.0 -3540.0 -0.02 833360.0 -127589.375 -0.730767178335623 -0.7188 -0.8151 1720964 Maybridge1_003096 O=S(=O)(NCC#C)c1ccc(C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E17 compound treatment 612960.0 -465000.0 -2.27 349140.0 -706000.0 -4.2 548480.0 -412469.375 -2.36241521928145 -5.0978 -0.9575 2070841 Maybridge1_003097 Clc1cc(c(Cl)s1)S(=O)(=O)NCCCNS(=O)(=O)c2cc(Cl)sc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E18 compound treatment 1024600.0 -53200.0 -0.26 897470.0 -157000.0 -0.94 654750.0 -306199.375 -1.75375459968262 -1.7027 -0.8494 2070842 Maybridge1_003098 Fc1ccc(c2ccc(CNC(=O)c3ccc(Cl)cc3)o2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E19 compound treatment 1306410.0 229000.0 1.12 1058720.0 3980.0 0.02 926150.0 -34799.375 -0.199313156574309 0.5433 0.4789 2070843 Maybridge1_003099 Cc1nn(C)c(C)c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E20 compound treatment 543860.0 -534000.0 -2.61 527280.0 -527000.0 -3.14 454880.0 -506069.375 -2.89850850990392 -4.9906 -0.9972 2070844 Maybridge1_003100 CN(C)c1cc(oc(=O)c1Cl)c2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E21 compound treatment 1044360.0 -33500.0 -0.16 1051160.0 -3580.0 -0.02 840410.0 -120539.375 -0.690388356766302 -0.5053 -0.7119 2070845 Maybridge1_003101 Cc1c([N+](=O)[O-])c(C/C=N/O)nn1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E22 compound treatment 838170.0 -240000.0 -1.17 813700.0 -241000.0 -1.43 624100.0 -336849.375 -1.9293022423918 -2.6175 -0.979 2070846 Maybridge1_003102 COc1ccc(OCC(F)(F)F)c(c1)C(=O)Nc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E23 mock treatment 1175210.0 97400.0 0.48 1057400.0 2660.0 0.02 964550.0 3600.625 0.0206225523990121 0.2957 0.6206 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 E24 mock treatment 1225970.0 148000.0 0.72 1143950.0 89200.0 0.53 982470.0 21520.625 0.123259216586562 0.7953 0.878 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F01 compound treatment 968720.0 -109000.0 -0.53 981240.0 -73500.0 -0.44 971840.0 10890.625 0.062375972149416 -0.5242 -0.7572 2070847 Maybridge1_003103 O=C1CC(CC(=O)C1)c2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F02 compound treatment 990680.0 -87200.0 -0.43 896680.0 -158000.0 -0.94 999240.0 38290.625 0.219309264489754 -0.6619 -0.6274 2070848 Maybridge1_003104 CC(C)C/1CCC(C)C\C1=N/NC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F03 compound treatment 1009830.0 -68000.0 -0.33 928880.0 -126000.0 -0.75 820930.0 -140019.375 -0.801959909130893 -1.087 -0.9483 2070849 Maybridge1_003105 CC1(C)OC(=O)C(CC#C)(CC#C)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F04 compound treatment 804970.0 -273000.0 -1.33 817240.0 -238000.0 -1.41 605450.0 -355499.375 -2.03611997604681 -2.7607 -0.9811 1413077 Maybridge1_003106 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F05 compound treatment 967610.0 -110000.0 -0.54 1118670.0 63900.0 0.38 824130.0 -136819.375 -0.783631933383116 -0.5439 -0.5311 2070850 Maybridge1_003107 CC(NC=C(C#N)C#N)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F06 compound treatment 1065400.0 -12400.0 -0.06 954250.0 -100000.0 -0.6 704770.0 -256179.375 -1.46726542877519 -1.2272 -0.7741 1183062 Maybridge1_003108 Cc1ccc(NC(=S)C(C#N)C(=O)N2CCOCC2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F07 compound treatment 1019760.0 -58100.0 -0.28 977450.0 -77300.0 -0.46 813440.0 -147509.375 -0.844858827365533 -0.917 -0.9144 1504515 Maybridge1_003109 Clc1ccc(Oc2cccc(Cl)c2C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F08 compound treatment 994810.0 -83000.0 -0.41 912570.0 -142000.0 -0.85 797460.0 -163489.375 -0.936384156255993 -1.263 -0.953 1083106 Maybridge1_003110 CC1CC(CC(C)(C)C1)NC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F09 compound treatment 1006880.0 -71000.0 -0.35 1124730.0 70000.0 0.42 1035840.0 74890.625 0.428935487104951 0.2878 0.4165 1521482 Maybridge1_003111 Nc1nn(cc1c2nnn[nH]2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F10 compound treatment 977940.0 -99900.0 -0.49 1026440.0 -28300.0 -0.17 789670.0 -171279.375 -0.981001322216987 -0.9454 -0.8528 1058518 Maybridge1_003112 OC(=O)c1ccccc1C(=O)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F11 compound treatment 936800.0 -141000.0 -0.69 1041380.0 -13400.0 -0.08 793760.0 -167189.375 -0.95757587821436 -0.9966 -0.8428 2070851 Maybridge1_003113 CC(=O)OC(C(OC(=O)C)C(=O)Nc1ccc(Cl)cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F12 compound treatment 906320.0 -172000.0 -0.84 947760.0 -107000.0 -0.64 754260.0 -206689.375 -1.18381182885098 -1.5346 -0.9689 2070852 Maybridge1_003114 Cn1c2CCCCc2c3CCCCc31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F13 compound treatment 426280.0 -652000.0 -3.18 441280.0 -613000.0 -3.65 412350.0 -548599.375 -3.14209876257671 -5.7582 -0.9976 2070853 Maybridge1_003115 Cc1nn(C)c(O)c1N=Nc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F14 compound treatment 1091360.0 13500.0 0.07 1221010.0 166000.0 0.99 667090.0 -293859.375 -1.68307734320526 -0.3628 -0.1857 2070854 Maybridge1_003116 [O-][N+](=O)c1ccc(cc1)C(=O)CSC2=NCCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F15 compound treatment 543710.0 -534000.0 -2.61 527240.0 -528000.0 -3.14 437670.0 -523279.375 -2.99707865447243 -5.0481 -0.9971 2070855 Maybridge1_003117 [O-][N+](=O)c1cc(C#N)cs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F16 compound treatment 952260.0 -126000.0 -0.61 1015490.0 -39300.0 -0.23 731240.0 -229709.375 -1.31565870438655 -1.2486 -0.8492 1264193 Maybridge1_003118 CC1CN=C(c2ccccc2)c3ccccc3C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F17 compound treatment 1093870.0 16000.0 0.08 1005660.0 -49100.0 -0.29 823940.0 -137009.375 -0.78472015694314 -0.5764 -0.6854 2070856 Maybridge1_003119 O=C1NCCCCC1N2CCS(=O)(=O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F18 compound treatment 894920.0 -183000.0 -0.89 1016120.0 -38600.0 -0.23 783360.0 -177589.375 -1.01714179939463 -1.2358 -0.8999 1181207 Maybridge1_003120 O=c1n(c(nc2ccccc12)c3ccccc3)C4(CCCCC4)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F19 compound treatment 882050.0 -196000.0 -0.96 848500.0 -206000.0 -1.23 725280.0 -235669.375 -1.34979455921678 -2.0397 -0.9904 2070857 Maybridge1_003121 FC(F)(F)c1ccc(cc1)C(=O)NC(=O)Nc2ccc(cc2)c3cnco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F20 compound treatment 570950.0 -507000.0 -2.48 602410.0 -452000.0 -2.69 460180.0 -500769.375 -2.86815280007166 -4.6388 -0.9982 2070858 Maybridge1_003122 Clc1ccc(cc1)c2csc(=N)n2c3cc(Cl)c(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F21 compound treatment 899140.0 -179000.0 -0.87 803300.0 -251000.0 -1.5 594400.0 -366549.375 -2.09940876730085 -2.5794 -0.9479 1562587 Maybridge1_003123 CC(=O)N1C=CC(C=C1)c2c[nH]c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F22 compound treatment 610160.0 -468000.0 -2.29 610720.0 -444000.0 -2.64 529300.0 -431649.375 -2.47226852391968 -4.2711 -0.9983 2070859 Maybridge1_003124 COc1ccc(CS/C(=N/N)/N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F23 mock treatment 1062040.0 -15800.0 -0.08 1017820.0 -36900.0 -0.22 951960.0 -8989.375 -0.0514865771836471 -0.2011 -0.8435 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 F24 mock treatment 928070.0 -150000.0 -0.73 961760.0 -93000.0 -0.55 885280.0 -75669.375 -0.433395771827945 -0.9919 -0.9778 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G01 compound treatment 1140480.0 62600.0 0.31 961670.0 -93100.0 -0.55 1018240.0 57290.625 0.328131620492179 0.0466 0.0654 2070860 Maybridge1_003125 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1NCCc2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G02 compound treatment 1057000.0 -20800.0 -0.1 948800.0 -106000.0 -0.63 884500.0 -76449.375 -0.437863215916466 -0.6753 -0.8726 1222526 Maybridge1_003126 CN(C1CC2CC1C=C2)C(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G03 compound treatment 1109540.0 31700.0 0.15 1065280.0 10500.0 0.06 964120.0 3170.625 0.0181597306579046 0.1361 0.8097 2070861 Maybridge1_003127 Clc1ccc(Oc2ccccc2N/N=C(\C#N)/C(=O)N3CCCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G04 compound treatment 995750.0 -82100.0 -0.4 1049060.0 -5680.0 -0.03 855690.0 -105259.375 -0.602872272570668 -0.5991 -0.8265 2070862 Maybridge1_003128 CC(=O)N1CCC(CC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G05 compound treatment 742240.0 -336000.0 -1.64 811640.0 -243000.0 -1.45 570790.0 -390159.375 -2.23463486336492 -3.0715 -0.9826 2070863 Maybridge1_003129 [O-][N+](=O)c1ccc(Sc2nc[nH]n2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G06 compound treatment 1088500.0 10700.0 0.05 1133440.0 78700.0 0.47 920560.0 -40389.375 -0.231329839208706 0.1667 0.3177 1701114 Maybridge1_003130 COC(CNc1cccc(F)c1C#N)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G07 compound treatment 998760.0 -79100.0 -0.39 1080270.0 25500.0 0.15 809950.0 -150999.375 -0.864847775915452 -0.6348 -0.6617 2070864 Maybridge1_003131 COC(=O)c1sccc1NC(=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G08 compound treatment 724000.0 -354000.0 -1.73 773930.0 -281000.0 -1.67 488690.0 -472259.375 -2.70486199114381 -3.5239 -0.9739 2070865 Maybridge1_003132 CCOC(=O)c1cnn(c1C)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G09 compound treatment 881920.0 -196000.0 -0.96 866820.0 -188000.0 -1.12 768130.0 -192819.375 -1.10437150896921 -1.8355 -0.9977 2070866 Maybridge1_003133 O=C(Oc1ccccc1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G10 compound treatment 1023060.0 -54800.0 -0.27 1198880.0 144000.0 0.86 876960.0 -83989.375 -0.481048508772164 0.0626 0.0614 1177640 Maybridge1_003134 CCOC(=O)c1cnc(Nc2nc(cs2)C(C)(C)C)nc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G11 compound treatment 609090.0 -469000.0 -2.29 582170.0 -473000.0 -2.81 415770.0 -545179.375 -3.12251073849628 -4.7475 -0.9922 2070867 Maybridge1_003135 Fc1c(CSC2=NCCN2)cccc1CSC3=NCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G12 compound treatment 1189600.0 112000.0 0.55 1224680.0 170000.0 1.01 880890.0 -80059.375 -0.458539463556926 0.634 0.5126 2070868 Maybridge1_003136 CC(=O)CC(=O)c1c(C)nn(c1O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G13 compound treatment 1204240.0 126000.0 0.62 1149820.0 95100.0 0.57 1019890.0 58940.625 0.337581982987126 0.8779 0.9724 2070869 Maybridge1_003137 CN(C)/C=C(\C#N)/C(=O)Nc1cc(C)on1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G14 compound treatment 1342880.0 265000.0 1.29 1320320.0 266000.0 1.58 847600.0 -113349.375 -0.649207686258016 1.2846 0.5994 1652979 Maybridge1_003138 NC(=O)c1cccc(C(=O)N)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G15 compound treatment 1055490.0 -22400.0 -0.11 1047880.0 -6860.0 -0.04 916540.0 -44409.375 -0.254354358741851 -0.2335 -0.8344 2070870 Maybridge1_003139 Clc1cccc(Cl)c1CC(Cc2c(Cl)cccc2Cl)(C#N)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G16 compound treatment 1220160.0 142000.0 0.7 1243800.0 189000.0 1.12 841500.0 -119449.375 -0.684145390027216 0.6555 0.4404 2070871 Maybridge1_003140 Cc1c(C)c(C)c(C(=O)C2CCN(CC2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G17 compound treatment 1136740.0 58900.0 0.29 1027630.0 -27100.0 -0.16 847370.0 -113579.375 -0.650525009514888 -0.3025 -0.4148 2070872 Maybridge1_003141 CC(O)c1nc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G18 compound treatment 1280130.0 202000.0 0.99 1102880.0 48100.0 0.29 925670.0 -35279.375 -0.202062352936475 0.6192 0.5905 2070873 Maybridge1_003142 Cc1cccc(C(=O)O)c1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G19 compound treatment 958500.0 -119000.0 -0.58 1002000.0 -52700.0 -0.31 752290.0 -208659.375 -1.1950949889207 -1.2077 -0.884 1353717 Maybridge1_003143 OCCCc1cc(n[nH]1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G20 compound treatment 996450.0 -81400.0 -0.4 1009350.0 -45400.0 -0.27 808930.0 -152019.375 -0.870689818185056 -0.8881 -0.893 1487603 Maybridge1_003144 Clc1ccc(NS(=O)(=O)CC(=O)CS(=O)(=O)Nc2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G21 compound treatment 887760.0 -190000.0 -0.93 804580.0 -250000.0 -1.49 641620.0 -319329.375 -1.82895657517272 -2.451 -0.9673 2070874 Maybridge1_003145 Cc1cn(nc1c2ccccc2)C(=O)Nc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G22 compound treatment 981050.0 -96800.0 -0.47 996400.0 -58300.0 -0.35 867360.0 -93589.375 -0.536032436015495 -0.7828 -0.9852 2070875 Maybridge1_003146 CCOC(=O)C(/C=N/c1ccc(Cl)cc1Cl)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G23 mock treatment 1041040.0 -36800.0 -0.18 1016900.0 -37800.0 -0.23 933620.0 -27329.375 -0.156528788188093 -0.3241 -0.9886 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 G24 mock treatment 1157780.0 79900.0 0.39 1263750.0 209000.0 1.24 1047570.0 86620.625 0.496118973205395 1.2295 0.882 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H01 compound treatment 1078910.0 1070.0 0.01 1101960.0 47200.0 0.28 1015000.0 54050.625 0.309574545047555 0.3439 0.8227 2070876 Maybridge1_003147 CC12CCC(=O)NC2=CC(=O)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H02 compound treatment 1156970.0 79100.0 0.39 1022400.0 -32300.0 -0.19 935050.0 -25899.375 -0.148338474025805 0.0265 0.0581 1018434 Maybridge1_003148 O=C(CC#N)N1CCOCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H03 compound treatment 46210.0 -1030000.0 -5.04 70900.0 -984000.0 -5.85 88480.0 -872469.375 -4.99706173302435 -9.1729 -0.9973 2070877 Maybridge1_003149 COc1cccc(CNC(=S)SCC(=O)C(C)(C)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H04 compound treatment 935740.0 -142000.0 -0.69 889140.0 -166000.0 -0.98 853440.0 -107509.375 -0.615759130518324 -1.3249 -0.9791 2070878 Maybridge1_003150 CC1CCCN(C1)S(=O)(=O)c2cc(Cl)ccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H05 compound treatment 955540.0 -122000.0 -0.6 972070.0 -82700.0 -0.49 874580.0 -86369.375 -0.494679940734573 -0.9144 -0.9957 1494113 Maybridge1_003151 Nc1oncc1c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H06 compound treatment 38090.0 -1040000.0 -5.08 44360.0 -1010000.0 -6.01 41040.0 -919909.375 -5.26877397348514 -9.4438 -0.9973 1370912 Maybridge1_003152 Clc1ccccc1NC(=S)C(C#N)C(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H07 compound treatment 966270.0 -112000.0 -0.55 1195200.0 140000.0 0.84 834290.0 -126659.375 -0.725440610383925 -0.2513 -0.2038 1262194 Maybridge1_003153 CNn1cnc2ccsc2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H08 compound treatment 1106770.0 28900.0 0.14 1234640.0 180000.0 1.07 884960.0 -75989.375 -0.435228569402723 0.448 0.385 1083104 Maybridge1_003154 O=C(CC#N)NCCc1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H09 compound treatment 1244830.0 167000.0 0.82 984400.0 -70300.0 -0.42 778150.0 -182799.375 -1.04698203490898 -0.3749 -0.2694 1311727 Maybridge1_003155 Clc1cccc(N2CCC(CC2)C#N)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H10 compound treatment 966090.0 -112000.0 -0.55 972800.0 -81900.0 -0.49 703090.0 -257859.375 -1.47688761604277 -1.4492 -0.8793 1742190 Maybridge1_003156 Fc1ccc(cc1)c2nn(c3ccccc3)c(=O)c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H11 compound treatment 959200.0 -119000.0 -0.58 1001390.0 -53400.0 -0.32 681690.0 -279259.375 -1.59945595385603 -1.4413 -0.8328 1029322 Maybridge1_003157 CC(=O)c1ccc(Oc2ccc(cc2)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H12 compound treatment 1101870.0 24000.0 0.12 1427300.0 373000.0 2.22 844900.0 -116049.375 -0.664671915795203 0.9631 0.4159 1055233 Maybridge1_003158 O=c1onc(c2ccccc2)c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H13 compound treatment 871790.0 -206000.0 -1.01 788440.0 -266000.0 -1.58 632750.0 -328199.375 -1.87975943294859 -2.5808 -0.9717 1074389 Maybridge1_003159 CC(=O)c1ccc(Sc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H14 compound treatment 899320.0 -179000.0 -0.87 970360.0 -84400.0 -0.5 1043080.0 82130.625 0.470402532234296 -0.5217 -0.4697 1929006 Maybridge1_003160 Brc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H15 compound treatment 1072280.0 -5560.0 -0.03 1080450.0 25700.0 0.15 797510.0 -163439.375 -0.936097781634934 -0.4679 -0.4931 1534999 Maybridge1_003161 C=CCN1CCS(=O)(=O)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H16 compound treatment 1043230.0 -34600.0 -0.17 1105030.0 50300.0 0.3 758160.0 -202789.375 -1.16147460840838 -0.5956 -0.4917 2070879 Maybridge1_003162 O=C(NCCCCCCNC(=O)NC1(CCCCC1)C#C)NC2(CCCCC2)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H17 compound treatment 566460.0 -511000.0 -2.5 668350.0 -386000.0 -2.3 478670.0 -482279.375 -2.76225146520404 -4.3639 -0.9972 2070880 Maybridge1_003163 CC(C)c1ccc(NC(=S)N/N=C(\C)/c2ccco2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H18 compound treatment 985350.0 -92500.0 -0.45 1007850.0 -46900.0 -0.28 797660.0 -163289.375 -0.935238657771757 -0.9619 -0.8944 1202690 Maybridge1_003164 Cc1c(C)c(C)c(C(=O)CCC(=O)O)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H19 compound treatment 1208800.0 131000.0 0.64 1101700.0 47000.0 0.28 807360.0 -153589.375 -0.879681981286309 0.0227 0.0203 2070881 Maybridge1_003165 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3cccc(c3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H20 compound treatment 734560.0 -343000.0 -1.68 720100.0 -335000.0 -1.99 510560.0 -450389.375 -2.5796017318926 -3.6066 -0.9842 1171356 Maybridge1_003166 CC(C)c1ccc(NC(=O)c2ccccc2N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H21 compound treatment 1029730.0 -48100.0 -0.24 1019520.0 -35200.0 -0.21 794010.0 -166939.375 -0.956144005109065 -0.8087 -0.8033 1330601 Maybridge1_003167 CCOC(=O)c1c(N)c(sc1Nc2ccccc2OC)C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H22 compound treatment 752840.0 -325000.0 -1.59 768590.0 -286000.0 -1.7 702520.0 -258429.375 -1.48015228672284 -2.7538 -0.9984 2070882 Maybridge1_003168 COc1cc(I)c(OC)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H23 mock treatment 1205960.0 128000.0 0.63 1066730.0 12000.0 0.07 867300.0 -93649.375 -0.536376085560766 0.0929 0.1123 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 H24 mock treatment 1142760.0 64900.0 0.32 1182360.0 128000.0 0.76 985920.0 24970.625 0.143019065439634 0.7038 0.8431 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I01 compound treatment 844530.0 -233000.0 -1.14 899520.0 -155000.0 -0.92 855420.0 -105529.375 -0.604418695524387 -1.54 -0.9707 2070883 Maybridge1_003169 CC(C)(C)c1csc(n1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I02 compound treatment 935520.0 -142000.0 -0.7 942770.0 -112000.0 -0.67 807200.0 -153749.375 -0.880598380073698 -1.2943 -0.992 2070884 Maybridge1_003170 CCCCNC(=O)N(C)C1CC2CC1C=C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I03 compound treatment 443460.0 -634000.0 -3.1 570080.0 -485000.0 -2.88 483840.0 -477109.375 -2.73264032938654 -5.0311 -0.9987 2070885 Maybridge1_003171 Clc1ccc(Oc2ccccc2NN=C(C#N)C#N)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I04 compound treatment 919520.0 -158000.0 -0.77 1115800.0 61100.0 0.36 812700.0 -148249.375 -0.849097171757206 -0.7272 -0.6037 2070886 Maybridge1_003172 Cc1c(O)c(C#N)sc1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I05 compound treatment 32410.0 -1050000.0 -5.11 37120.0 -1020000.0 -6.05 37280.0 -923669.375 -5.29030934498878 -9.4971 -0.9972 2070887 Maybridge1_003173 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2nc[nH]n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I06 compound treatment 924850.0 -153000.0 -0.75 1041170.0 -13600.0 -0.08 716530.0 -244419.375 -1.39991011790211 -1.2864 -0.8096 1437874 Maybridge1_003174 Clc1ccc(cc1)C(=O)C2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I07 compound treatment 1149600.0 71800.0 0.35 1081310.0 26600.0 0.16 833890.0 -127059.375 -0.727731607352397 -0.1265 -0.1537 2070888 Maybridge1_003175 Cc1onc(c1C(=O)c2ccc(F)cc2)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I08 compound treatment 1064660.0 -13200.0 -0.06 1072190.0 17400.0 0.1 782760.0 -178189.375 -1.02057829484734 -0.5665 -0.5512 1265175 Maybridge1_003176 CCOC(=O)c1cnc(N)nc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I09 compound treatment 1167320.0 89500.0 0.44 1079540.0 24800.0 0.15 752740.0 -208209.375 -1.19251761733117 -0.351 -0.2745 1708110 Maybridge1_003177 Cc1onc(c1C(=O)Oc2ccccc2)c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I10 compound treatment 816160.0 -262000.0 -1.28 771390.0 -283000.0 -1.68 646960.0 -313989.375 -1.79837176564362 -2.7493 -0.9903 2070889 Maybridge1_003178 CCCc1c(cnn1c2c(Cl)cc(Cl)cc2Cl)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I11 compound treatment 1018760.0 -59100.0 -0.29 1013120.0 -41600.0 -0.25 776410.0 -184539.375 -1.05694787172184 -0.9198 -0.8189 2070890 Maybridge1_003179 Clc1cccc(NCCCN2CCCCC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I12 compound treatment 1263970.0 186000.0 0.91 1140240.0 85500.0 0.51 786730.0 -174219.375 -0.997840149935257 0.2425 0.1681 1604920 Maybridge1_003180 NC(=O)C1CCN(CC1)C(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I13 compound treatment 1183080.0 105000.0 0.51 1064840.0 10100.0 0.06 747520.0 -213429.375 -1.22241512776973 -0.3742 -0.2819 1611997 Maybridge1_003181 Cc1cc(NC(=O)c2ccccc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I14 compound treatment 1394990.0 317000.0 1.55 1121690.0 66900.0 0.4 803610.0 -157339.375 -0.901160077865734 0.6042 0.329 2070891 Maybridge1_003182 Cc1noc(C)c1S(=O)(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I15 compound treatment 1011040.0 -66800.0 -0.33 978690.0 -76100.0 -0.45 792050.0 -168899.375 -0.967369890254578 -1.0081 -0.9028 1451795 Maybridge1_003183 Cc1cccn(Cc2c(F)cccc2Cl)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I16 compound treatment 1009920.0 -67900.0 -0.33 1026990.0 -27800.0 -0.17 726720.0 -234229.375 -1.34154697013028 -1.0614 -0.7626 2070892 Maybridge1_003184 O=C(Nc1ccccc1)OC2CCSC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I17 compound treatment 980910.0 -96900.0 -0.47 1018240.0 -36500.0 -0.22 780320.0 -180629.375 -1.03455337635502 -0.9961 -0.8599 1173925 Maybridge1_003185 Clc1sc(Cl)c(c1Br)S(=O)(=O)N2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I18 compound treatment 915270.0 -163000.0 -0.79 918270.0 -136000.0 -0.81 733360.0 -227589.375 -1.30351642045365 -1.6797 -0.9716 1703198 Maybridge1_003186 NC(=O)c1cccc2cccc(C(=O)O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I19 compound treatment 1009450.0 -68400.0 -0.33 1028190.0 -26600.0 -0.16 843910.0 -117039.375 -0.670342133292171 -0.6711 -0.8767 2070893 Maybridge1_003187 N/C(=N\O)/CSc1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I20 compound treatment 1071110.0 -6730.0 -0.03 976160.0 -78600.0 -0.47 722470.0 -238479.375 -1.3658888129203 -1.0774 -0.7461 2070894 Maybridge1_003188 CN(C)/C=C/C(=N)SCc1cc(F)cc2COCOc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I21 compound treatment 1032360.0 -45500.0 -0.22 919840.0 -135000.0 -0.8 692120.0 -268829.375 -1.53971820790312 -1.4804 -0.8458 2070895 Maybridge1_003189 Cc1c[nH]nc1c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I22 compound treatment 1156850.0 79000.0 0.39 1275490.0 221000.0 1.31 877730.0 -83219.375 -0.476638339607856 0.7056 0.487 2070896 Maybridge1_003190 Clc1ccc(C2CC(=O)CC(=O)C2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I23 mock treatment 1205440.0 128000.0 0.62 1109710.0 55000.0 0.33 947750.0 -13199.375 -0.0755993202768158 0.505 0.7133 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 I24 mock treatment 1212200.0 134000.0 0.66 1090920.0 36200.0 0.22 1065920.0 104970.625 0.601218459134052 0.8503 0.9285 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J01 compound treatment 590000.0 -488000.0 -2.38 478310.0 -576000.0 -3.43 299480.0 -661469.375 -3.78856083215533 -5.5425 -0.9831 2070897 Maybridge1_003191 NC(=N)Nc1nc(cs1)c2cc(Cl)sc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J02 compound treatment 932730.0 -145000.0 -0.71 942740.0 -112000.0 -0.67 917340.0 -43609.375 -0.249772364804907 -0.9381 -0.934 1642787 Maybridge1_003192 COC(=O)c1sc(NCC=C)c(C(=O)OC)c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J03 compound treatment 1100600.0 22800.0 0.11 1003150.0 -51600.0 -0.31 1010040.0 49090.625 0.281166182638501 0.0494 0.1147 2070898 Maybridge1_003193 COc1cc2COC(=O)/C(=C\N(C)C)/c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J04 compound treatment 1004290.0 -73600.0 -0.36 874560.0 -180000.0 -1.07 809540.0 -151409.375 -0.867196047808136 -1.3268 -0.9314 2070899 Maybridge1_003194 CC1CCCN(C1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J05 compound treatment 1092320.0 14500.0 0.07 1127050.0 72300.0 0.43 919250.0 -41699.375 -0.238832854280452 0.1512 0.3043 2070900 Maybridge1_003195 C(SCc1nnn[nH]1)c2nnn[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J06 compound treatment 1197350.0 120000.0 0.58 1220050.0 165000.0 0.98 908800.0 -52149.375 -0.298685150081786 0.7322 0.6196 1282320 Maybridge1_003196 COc1ccccc1NC(=S)C(C#N)C(=O)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J07 compound treatment 1278510.0 201000.0 0.98 1246470.0 192000.0 1.14 768610.0 -192339.375 -1.10162231260704 0.5883 0.3156 2070901 Maybridge1_003197 Oc1nccn(c2cccc(c2)C(F)(F)F)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J08 compound treatment 931140.0 -147000.0 -0.72 757280.0 -297000.0 -1.77 614080.0 -346869.375 -1.98669171645202 -2.5821 -0.9373 2070902 Maybridge1_003198 Cc1ccc(CC(=O)c2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J09 compound treatment 825700.0 -252000.0 -1.23 633310.0 -421000.0 -2.51 608510.0 -352439.375 -2.018593849238 -3.3236 -0.9646 2070903 Maybridge1_003199 CC(=O)c1ccc(o1)c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J10 compound treatment 1011420.0 -66400.0 -0.32 974650.0 -80100.0 -0.48 730360.0 -230589.375 -1.32069889771719 -1.2248 -0.85 1006292 Maybridge1_003200 Oc1nnc(c2ccccc2)c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J11 compound treatment 1083520.0 5680.0 0.03 916800.0 -138000.0 -0.82 636380.0 -324569.375 -1.8589686354597 -1.5309 -0.7533 2070904 Maybridge1_003201 CC(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J12 compound treatment 1151800.0 74000.0 0.36 1014110.0 -40600.0 -0.24 93930.0 -867019.375 -4.96584689932892 -2.7979 -0.5613 1401466 Maybridge1_003202 O=C(Nc1ccccc1C(=O)Nc2ccncc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J13 compound treatment 698810.0 -379000.0 -1.85 758360.0 -296000.0 -1.76 571490.0 -389459.375 -2.23062561867009 -3.3746 -0.9946 2070905 Maybridge1_003203 Cc1nn(c(O)c1N=Nc2ccc(C)cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J14 compound treatment 1273090.0 195000.0 0.95 1218490.0 164000.0 0.97 820610.0 -140339.375 -0.803792706705671 0.6489 0.41 1730722 Maybridge1_003204 CCOC(=O)c1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J15 compound treatment 1419120.0 341000.0 1.67 1289830.0 235000.0 1.4 801340.0 -159609.375 -0.914161485661814 1.242 0.5262 1091121 Maybridge1_003205 O=S1(=O)CCN(Cc2ccccc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J16 compound treatment 726330.0 -352000.0 -1.72 755450.0 -299000.0 -1.78 610850.0 -350099.375 -2.00519151697244 -3.1768 -0.9977 1049219 Maybridge1_003206 Nc1sc2CCCc2c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J17 compound treatment 1088840.0 11000.0 0.05 1148160.0 93400.0 0.56 812050.0 -148899.375 -0.852820041830973 -0.1406 -0.138 2070906 Maybridge1_003207 N#Cc1ccc(cc1)c2cnco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J18 compound treatment 805160.0 -273000.0 -1.33 842530.0 -212000.0 -1.26 584190.0 -376759.375 -2.1578864649211 -2.7436 -0.9686 1087389 Maybridge1_003208 Cn1ncc2ccccc2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J19 compound treatment 1106970.0 29100.0 0.14 1167530.0 113000.0 0.67 878890.0 -82059.375 -0.469994448399287 0.198 0.2382 1393767 Maybridge1_003209 CCOC(=O)c1cnc2ccc(Cl)cc2c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J20 compound treatment 298040.0 -780000.0 -3.81 253450.0 -801000.0 -4.76 227360.0 -733589.375 -4.20162758557084 -7.3765 -0.9958 2070907 Maybridge1_003210 Clc1ccc(CSc2nsc(Nc3ccc(Cl)cc3)c2C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J21 compound treatment 1161760.0 83900.0 0.41 1139040.0 84300.0 0.5 942280.0 -18669.375 -0.106928703820672 0.4644 0.7075 1395752 Maybridge1_003211 CCOC(=O)c1c(N)c(sc1Nc2ccccc2OC)C(=O)c3ccc(Br)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J22 compound treatment 1048880.0 -29000.0 -0.14 945380.0 -109000.0 -0.65 779700.0 -181249.375 -1.03810442165615 -1.0565 -0.8568 2070908 Maybridge1_003212 O=C/1/C(=C/c2ccc3OCOc3c2)/CCC\C1=C/c4ccc5OCOc5c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J23 mock treatment 1099930.0 22100.0 0.11 1138880.0 84100.0 0.5 954050.0 -6899.375 -0.0395161180233804 0.3284 0.6396 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 J24 mock treatment 1215950.0 138000.0 0.67 1130400.0 75700.0 0.45 1048700.0 87750.625 0.502591039641329 0.9395 0.9847 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K01 compound treatment 902180.0 -176000.0 -0.86 862270.0 -192000.0 -1.14 779150.0 -181799.375 -1.0412545424878 -1.7575 -0.9933 2070909 Maybridge1_003213 NCCSCc1c(Cl)cccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K02 compound treatment 1081230.0 3390.0 0.02 941000.0 -114000.0 -0.68 1101520.0 140570.625 0.805117189328069 0.0839 0.0798 2070910 Maybridge1_003214 CC(=O)c1nnn(c1C)c2ccc(F)cc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K03 compound treatment 1101080.0 23200.0 0.11 1125460.0 70700.0 0.42 936180.0 -24769.375 -0.141866407589871 0.2264 0.4943 1650150 Maybridge1_003215 OC(=O)c1nnn(c1c2ccccc2)c3ccccc3Oc4ccc(Cl)cc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K04 compound treatment 1232110.0 154000.0 0.75 1167860.0 113000.0 0.67 865970.0 -94979.375 -0.543993650480935 0.5095 0.444 2070911 Maybridge1_003216 COC(CN/C(=N\C#N)/SC)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K05 compound treatment 1259150.0 181000.0 0.89 1205610.0 151000.0 0.9 799290.0 -161659.375 -0.925902845125233 0.4948 0.3163 1005731 Maybridge1_003217 CCCCCCCCCCCC(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K06 compound treatment 1101680.0 23800.0 0.12 1242150.0 187000.0 1.11 853780.0 -107169.375 -0.613811783095122 0.3563 0.2789 2070912 Maybridge1_003218 Cc1nn(C)c(C)c1NC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K07 compound treatment 797760.0 -280000.0 -1.37 791480.0 -263000.0 -1.57 682250.0 -278699.375 -1.59624855810017 -2.6155 -0.9978 2070913 Maybridge1_003219 Cc1nn(C)c(O)c1C(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K08 compound treatment 964700.0 -113000.0 -0.55 853060.0 -202000.0 -1.2 789440.0 -171509.375 -0.982318645473858 -1.5787 -0.9592 2070914 Maybridge1_003220 Cc1cc(C)n(n1)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K09 compound treatment 1051690.0 -26200.0 -0.13 983250.0 -71500.0 -0.43 760730.0 -200219.375 -1.14675495288594 -0.9813 -0.798 1459994 Maybridge1_003221 Clc1ccc(Oc2ccccc2C#N)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K10 compound treatment 1133210.0 55400.0 0.27 1071740.0 17000.0 0.1 720480.0 -240469.375 -1.37728652283845 -0.5806 -0.4126 2070915 Maybridge1_003222 CCOC(=O)c1cnn(c1COC)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K11 compound treatment 832480.0 -245000.0 -1.2 825290.0 -229000.0 -1.36 660670.0 -300279.375 -1.71984784454924 -2.4728 -0.9886 2070916 Maybridge1_003223 CSc1cc(cc(SC)c1SC)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K12 compound treatment 1244910.0 167000.0 0.82 1219200.0 164000.0 0.98 834490.0 -126459.375 -0.724295111899689 0.6177 0.4215 2070917 Maybridge1_003224 CCCCNC(=O)NS(=O)(=O)c1cc(Cl)sc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K13 compound treatment 1152820.0 75000.0 0.37 1193840.0 139000.0 0.83 813940.0 -147009.375 -0.841995081154943 0.2029 0.1642 1108929 Maybridge1_003225 CC(=O)Cc1ncn(n1)c2cc(C)on2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K14 compound treatment 1290500.0 213000.0 1.04 1238030.0 183000.0 1.09 876050.0 -84899.375 -0.486260526875438 0.9484 0.5993 2070918 Maybridge1_003226 Fc1c(CC#N)cccc1CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K15 compound treatment 1257310.0 179000.0 0.88 1149220.0 94500.0 0.56 876960.0 -83989.375 -0.481048508772164 0.5529 0.482 1936403 Maybridge1_003227 CN(C)/C=N/S(=O)(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K16 compound treatment 847420.0 -230000.0 -1.13 828720.0 -226000.0 -1.34 493170.0 -467779.375 -2.67920282509693 -2.9728 -0.9285 2070919 Maybridge1_003228 FC(F)(F)c1ccc(CNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K17 compound treatment 1143090.0 65200.0 0.32 1159620.0 105000.0 0.62 767530.0 -193419.375 -1.10780800442192 -0.0955 -0.0728 2070920 Maybridge1_003229 Clc1sc(Cl)c(c1Br)S(=O)(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K18 compound treatment 1294280.0 216000.0 1.06 1197810.0 143000.0 0.85 829690.0 -131259.375 -0.751787075521354 0.6677 0.4303 2070921 Maybridge1_003230 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1NCCC2CC2(Cl)Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K19 compound treatment 999200.0 -78600.0 -0.38 926730.0 -128000.0 -0.76 569570.0 -391379.375 -2.24162240411876 -1.9555 -0.8154 2070922 Maybridge1_003231 CN(C)/C=C(\C#N)/c1nc(cs1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K20 compound treatment 908320.0 -170000.0 -0.83 1146160.0 91400.0 0.54 787550.0 -173399.375 -0.993143606149889 -0.7377 -0.5259 2070923 Maybridge1_003232 NC(=O)N/1CCCCC\C1=N/O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K21 compound treatment 1269480.0 192000.0 0.94 1240540.0 186000.0 1.1 822120.0 -138829.375 -0.795144193149688 0.7194 0.4354 1068856 Maybridge1_003233 CC(=O)c1cnn(c1C)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K22 compound treatment 1247000.0 169000.0 0.83 1208840.0 154000.0 0.92 862560.0 -98389.375 -0.56352439963716 0.6809 0.5019 1510203 Maybridge1_003234 CN(C)c1ccc(cc1)C2CC(=O)CC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K23 mock treatment 1179800.0 102000.0 0.5 1116580.0 61800.0 0.37 990560.0 29610.625 0.16959463027391 0.5978 0.9312 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 K24 mock treatment 1172440.0 94600.0 0.46 1000660.0 -54100.0 -0.32 875900.0 -85049.375 -0.487119650738616 -0.2001 -0.2687 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L01 compound treatment 1225560.0 148000.0 0.72 1147390.0 92600.0 0.55 1064800.0 103850.625 0.59480366762233 1.0782 0.9933 2070924 Maybridge1_003235 CCOC(=O)CC1NCCNC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L02 compound treatment 1137170.0 59300.0 0.29 1009720.0 -45000.0 -0.27 812160.0 -148789.375 -0.852190017664644 -0.4792 -0.5103 2070925 Maybridge1_003236 COc1cccc(/C=N/NC(=O)CC#N)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L03 compound treatment 1055070.0 -22800.0 -0.11 843680.0 -211000.0 -1.26 759520.0 -201429.375 -1.15368521871557 -1.4549 -0.8516 2070926 Maybridge1_003237 FC(F)(F)c1ccc(cc1)C2CC(=CC(=O)C2)Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L04 compound treatment 1142580.0 64700.0 0.32 1021490.0 -33300.0 -0.2 797490.0 -163459.375 -0.936212331483358 -0.4721 -0.4684 2070927 Maybridge1_003238 CC1CCN(CC1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L05 compound treatment 441940.0 -636000.0 -3.11 438030.0 -617000.0 -3.67 321620.0 -639329.375 -3.66175414995039 -6.0252 -0.9972 1517662 Maybridge1_003239 Clc1ccc(cc1)C2CC(=O)C=C(C2)NCc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L06 compound treatment 559110.0 -519000.0 -2.53 493320.0 -561000.0 -3.34 527240.0 -433709.375 -2.48406715830732 -4.8249 -0.9903 1557130 Maybridge1_003240 COc1ccccc1NC(=S)C(C#N)C(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L07 compound treatment 1289280.0 211000.0 1.03 1180960.0 126000.0 0.75 799870.0 -161079.375 -0.922580899520949 0.4971 0.3156 2070928 Maybridge1_003241 CC1=C(C#N)S(=O)(=O)C(C#N)C(C1)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L08 compound treatment 645180.0 -433000.0 -2.11 592000.0 -463000.0 -2.75 459590.0 -501359.375 -2.87153202060016 -4.4671 -0.9918 2070929 Maybridge1_003242 Clc1ccc(/N=C\2/C(=O)Nc3ccc(Br)cc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L09 compound treatment 703090.0 -375000.0 -1.83 801710.0 -253000.0 -1.5 549120.0 -411829.375 -2.35874962413189 -3.2877 -0.9832 2070930 Maybridge1_003243 CC(=O)c1ccc(o1)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L10 compound treatment 1098520.0 20700.0 0.1 996480.0 -58300.0 -0.35 755700.0 -205249.375 -1.17556423976448 -0.8204 -0.6672 1205536 Maybridge1_003244 Fc1ccc(cc1)c2n[nH]c(=O)c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L11 compound treatment 1019370.0 -58500.0 -0.29 1034630.0 -20100.0 -0.12 677180.0 -283769.375 -1.62528694467555 -1.1724 -0.7086 2070931 Maybridge1_003245 COc1ccc(Oc2ccc(cc2)C(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L12 compound treatment 666740.0 -411000.0 -2.01 676390.0 -378000.0 -2.25 474120.0 -486829.375 -2.78831155572041 -4.0685 -0.9905 1517312 Maybridge1_003246 O=C(Nc1nccs1)c2ccccc2NC(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L13 compound treatment 521090.0 -557000.0 -2.72 687120.0 -368000.0 -2.19 495250.0 -465699.375 -2.66728964086087 -4.3726 -0.9955 1386165 Maybridge1_003247 CSc1cc(n[nH]1)c2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L14 compound treatment 770810.0 -307000.0 -1.5 872820.0 -182000.0 -1.08 663790.0 -297159.375 -1.70197806819515 -2.4733 -0.984 2070932 Maybridge1_003248 COc1cc(/C=N/NC(=S)N\N=C\c2ccc(O)c(OC)c2)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L15 compound treatment 1183720.0 106000.0 0.52 1232490.0 178000.0 1.06 1053190.0 92240.625 0.528307480612428 1.2139 0.9411 2070933 Maybridge1_003249 OC(=O)c1csc(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L16 compound treatment 732120.0 -346000.0 -1.69 724100.0 -331000.0 -1.97 622000.0 -338949.375 -1.94132997647628 -3.2312 -0.9978 1453213 Maybridge1_003250 Nc1sc2CCCCCc2c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L17 compound treatment 1106050.0 28200.0 0.14 1119300.0 64600.0 0.38 717890.0 -243059.375 -1.3921207282093 -0.5025 -0.3464 2070934 Maybridge1_003251 [O-][N+](=O)c1ccccc1c2cnco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L18 compound treatment 1238850.0 161000.0 0.79 1172900.0 118000.0 0.7 944290.0 -16659.375 -0.0954164440540994 0.8048 0.7599 1026020 Maybridge1_003252 O=c1n(ncc2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L19 compound treatment 891800.0 -186000.0 -0.91 722240.0 -333000.0 -1.98 676840.0 -284109.375 -1.62723429209875 -2.6058 -0.959 2070935 Maybridge1_003253 COC(=O)c1cccc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L20 compound treatment 753530.0 -324000.0 -1.58 805520.0 -249000.0 -1.48 540420.0 -420529.375 -2.40857880819616 -3.1611 -0.9751 1569306 Maybridge1_003254 Cc1ccc(NC(=O)c2ccccc2N)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L21 compound treatment 1109130.0 31300.0 0.15 1069510.0 14800.0 0.09 808330.0 -152619.375 -0.874126313637764 -0.3657 -0.4101 2070936 Maybridge1_003255 COc1ccc(/C=N/NC(=O)CC#N)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L22 compound treatment 1196810.0 119000.0 0.58 1067400.0 12700.0 0.08 757000.0 -203949.375 -1.16811849961695 -0.2954 -0.226 2070937 Maybridge1_003256 Clc1ccc(/C=C/2\CCC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L23 mock treatment 1252190.0 174000.0 0.85 1172380.0 118000.0 0.7 992340.0 31390.625 0.179789566783611 0.9995 0.8949 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 L24 mock treatment 1005400.0 -72400.0 -0.35 966050.0 -88700.0 -0.53 949280.0 -11669.375 -0.0668362568724101 -0.5474 -0.8571 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M01 compound treatment 1087760.0 9920.0 0.05 1187840.0 133000.0 0.79 1055170.0 94220.625 0.539647915606365 0.7965 0.8304 2070938 Maybridge1_003257 NC(CSCc1c(F)cccc1Cl)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M02 compound treatment 1065800.0 -12000.0 -0.06 1106500.0 51800.0 0.31 817840.0 -143109.375 -0.81965786071234 -0.3295 -0.3755 2070939 Maybridge1_003258 Cc1nn(C)c(C)c1NS(=O)(=O)c2cc(Cl)sc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M03 compound treatment 870340.0 -208000.0 -1.01 768670.0 -286000.0 -1.7 793280.0 -167669.375 -0.960325074576526 -2.1219 -0.9641 1504154 Maybridge1_003259 Fc1cc(CSc2nc3ccccc3[nH]2)c4OCOCc4c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M04 compound treatment 1125340.0 47500.0 0.23 1083170.0 28400.0 0.17 805760.0 -155189.375 -0.888845969160197 -0.2816 -0.3015 2070940 Maybridge1_003260 CC(=O)c1nnn(c1C)c2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M05 compound treatment 1319010.0 241000.0 1.18 1269800.0 215000.0 1.28 868740.0 -92209.375 -0.528128496474266 1.1137 0.6128 2070941 Maybridge1_003261 COC(=O)c1sccc1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M06 compound treatment 874350.0 -203000.0 -0.99 933510.0 -121000.0 -0.72 752050.0 -208899.375 -1.19646958710179 -1.681 -0.9804 2070942 Maybridge1_003262 CS/C(=N\C#N)/N1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M07 compound treatment 986120.0 -91700.0 -0.45 1036160.0 -18600.0 -0.11 721610.0 -239339.375 -1.37081445640251 -1.114 -0.7702 2070943 Maybridge1_003263 Cc1onc(c1C(=O)c2ccc(F)cc2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M08 compound treatment 1165530.0 87700.0 0.43 1099460.0 44700.0 0.27 787750.0 -173199.375 -0.991998107665653 -0.1719 -0.1544 2070944 Maybridge1_003264 CC(=O)c1cnc(N)nc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M09 compound treatment 1176890.0 99000.0 0.48 1170880.0 116000.0 0.69 829240.0 -131709.375 -0.754364447110885 0.2426 0.2144 2070945 Maybridge1_003265 CN(C)c1cccc(N(C)C)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M10 compound treatment 1152520.0 74700.0 0.36 1211410.0 157000.0 0.93 900240.0 -60709.375 -0.347712485207089 0.5478 0.5172 2070946 Maybridge1_003266 NC(=O)C1CCN(CC1)c2ncccc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M11 compound treatment 41220.0 -1040000.0 -5.06 42290.0 -1010000.0 -6.02 34270.0 -926679.375 -5.30754909717653 -9.4645 -0.9973 2070947 Maybridge1_003267 CS(=O)(=O)c1cc(cc(c1S(=O)(=O)C)S(=O)(=O)C)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M12 compound treatment 1306980.0 229000.0 1.12 1296640.0 242000.0 1.44 793660.0 -167289.375 -0.958148627456478 0.9237 0.4485 1469154 Maybridge1_003268 Clc1ccc(NC(=O)NC(=O)C2CCN(CC2)c3cccc(Cl)c3C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M13 compound treatment 631440.0 -446000.0 -2.18 662890.0 -392000.0 -2.33 530530.0 -430419.375 -2.46522370824163 -4.0279 -0.9988 2070948 Maybridge1_003269 Nc1oc(c(C#N)c1c2ccc(Cl)cc2Cl)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M14 compound treatment 1185450.0 108000.0 0.53 1227770.0 173000.0 1.03 803710.0 -157239.375 -0.900587328623616 0.3776 0.2578 2070949 Maybridge1_003270 CNC(=O)c1cnn(c1COC)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M15 compound treatment 1229080.0 151000.0 0.74 1221000.0 166000.0 0.99 777720.0 -183229.375 -1.04944485665009 0.3915 0.2417 1054566 Maybridge1_003271 NC(=O)c1ccc(cc1C(=O)N)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M16 compound treatment 939310.0 -139000.0 -0.68 923760.0 -131000.0 -0.78 716500.0 -244449.375 -1.40008194267474 -1.6488 -0.948 2070950 Maybridge1_003272 Fc1ccc(CNS(=O)(=O)c2cccc(c2)C(F)(F)F)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M17 compound treatment 1282100.0 204000.0 1.0 1238050.0 183000.0 1.09 902490.0 -58459.375 -0.334825627259433 1.0122 0.668 2070951 Maybridge1_003273 CC(OS(=O)(=O)c1ccc(Cl)cc1)c2nc3ccccc3[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M18 compound treatment 1081400.0 3560.0 0.02 1018360.0 -36400.0 -0.22 738500.0 -222449.375 -1.27407710940878 -0.8505 -0.658 2070952 Maybridge1_003274 Cc1nc(NC(=N)N)sc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M19 compound treatment 344480.0 -733000.0 -3.58 364040.0 -691000.0 -4.11 307410.0 -653539.375 -3.74314181725537 -6.6011 -0.9983 2070953 Maybridge1_003275 N/C(=N\OCc1c(F)cccc1Cl)/c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M20 compound treatment 1018170.0 -59700.0 -0.29 956270.0 -98500.0 -0.59 647880.0 -313069.375 -1.79310247261613 -1.5417 -0.8077 2070954 Maybridge1_003276 CC(=O)C1=C(C)Nc2ccccc2S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M21 compound treatment 896730.0 -181000.0 -0.88 988980.0 -65800.0 -0.39 771040.0 -189909.375 -1.08770450602357 -1.3647 -0.9375 2070955 Maybridge1_003277 CC(=O)c1cnn(c1C)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M22 compound treatment 988770.0 -89100.0 -0.44 1122100.0 67400.0 0.4 885660.0 -75289.375 -0.431219324707896 -0.269 -0.3675 1326338 Maybridge1_003278 O=C1CC(CC(=O)C1)c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M23 mock treatment 1187930.0 110000.0 0.54 1081730.0 27000.0 0.16 1062110.0 101160.625 0.579396713009356 0.7377 0.9145 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 M24 mock treatment 1054250.0 -23600.0 -0.12 1003040.0 -51700.0 -0.31 895100.0 -65849.375 -0.377151796251955 -0.4618 -0.9235 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N01 compound treatment 958260.0 -120000.0 -0.58 1036700.0 -18000.0 -0.11 1007390.0 46440.625 0.265988327722373 -0.2457 -0.3775 2070956 Maybridge1_003279 N#CC1CN(Cc2ccccc2)CN(Cc3ccccc3)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N02 compound treatment 1126240.0 48400.0 0.24 1060210.0 5470.0 0.03 1082280.0 121330.625 0.694920235144561 0.5565 0.7574 1083103 Maybridge1_003280 Cc1ccc(NC(=O)CC#N)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N03 compound treatment 966430.0 -111000.0 -0.54 980290.0 -74500.0 -0.44 886450.0 -74499.375 -0.426694605695164 -0.8162 -0.9939 1644674 Maybridge1_003281 COc1cc(CO)c(cc1OC)c2c[nH][nH]c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N04 compound treatment 1258300.0 180000.0 0.88 1217760.0 163000.0 0.97 904730.0 -56219.375 -0.321996044235989 0.8828 0.6542 1437622 Maybridge1_003282 COc1ccc(CCNS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N05 compound treatment 1114100.0 36300.0 0.18 998980.0 -55800.0 -0.33 830520.0 -130429.375 -0.747033256811774 -0.5205 -0.6223 1322518 Maybridge1_003283 Clc1cccc(Oc2ccccc2)c1CNC(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N06 compound treatment 1046880.0 -31000.0 -0.15 1049170.0 -5570.0 -0.03 752970.0 -207979.375 -1.1912002940743 -0.7942 -0.6612 1211475 Maybridge1_003284 COc1cccc(NC(=S)C(C#N)C(=O)N2CCCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N07 compound treatment 1274350.0 197000.0 0.96 706240.0 -349000.0 -2.07 973400.0 12450.625 0.0713108603264571 -0.601 -0.263 1530793 Maybridge1_003285 CCOC(=O)c1cc(C#N)c2ccccn2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N08 compound treatment 1081650.0 3810.0 0.02 1059600.0 4860.0 0.03 803490.0 -157459.375 -0.901847376956276 -0.4933 -0.5466 1533510 Maybridge1_003286 Clc1ccc(cc1)c2nn(c3ccccc3)c(=O)c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N09 compound treatment 1236990.0 159000.0 0.78 1069700.0 15000.0 0.09 879070.0 -81879.375 -0.468963499763474 0.2295 0.2516 2070957 Maybridge1_003287 OCC(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N10 compound treatment 1332390.0 255000.0 1.24 1259040.0 204000.0 1.21 834210.0 -126739.375 -0.725898809777619 1.0003 0.531 1021562 Maybridge1_003288 COc1ccc(cc1)C(=O)c2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N11 compound treatment 870560.0 -207000.0 -1.01 756260.0 -298000.0 -1.77 645490.0 -315459.375 -1.80679117950275 -2.6526 -0.9725 1660239 Maybridge1_003289 COc1ccc(Oc2ccc(cc2)c3ccn[nH]3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N12 compound treatment 973920.0 -104000.0 -0.51 1005370.0 -49400.0 -0.29 801800.0 -159149.375 -0.911526839148071 -0.9889 -0.9124 2070958 Maybridge1_003290 FC(F)(F)c1cccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N13 compound treatment 1301460.0 224000.0 1.09 1332360.0 278000.0 1.65 980660.0 19710.625 0.112892455304226 1.6491 0.8317 2070959 Maybridge1_003291 Cc1nccnc1c2ccn[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N14 compound treatment 1157350.0 79500.0 0.39 1106800.0 52100.0 0.31 842290.0 -118659.375 -0.679620671014483 0.0106 0.0126 1917407 Maybridge1_003292 COc1cc(/C=N/NC(=S)N)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N15 compound treatment 1328510.0 251000.0 1.22 1201170.0 146000.0 0.87 840320.0 -120629.375 -0.690903831084208 0.8109 0.4903 1091122 Maybridge1_003293 O=S1(=O)CCN(Cc2ccco2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N16 compound treatment 798490.0 -279000.0 -1.36 765920.0 -289000.0 -1.72 616570.0 -344379.375 -1.97243026032329 -2.9184 -0.9892 1636044 Maybridge1_003294 Cc1ccc(Nc2ncnc3ccccc23)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N17 compound treatment 1004490.0 -73400.0 -0.36 999450.0 -55300.0 -0.33 706880.0 -254069.375 -1.4551804197665 -1.2369 -0.8062 2070960 Maybridge1_003295 Clc1ccc(/N=C/c2ccc(C#N)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N18 compound treatment 1081650.0 3810.0 0.02 1008650.0 -46100.0 -0.27 847270.0 -113679.375 -0.651097758757006 -0.5234 -0.7407 1191412 Maybridge1_003296 O=c1n(Cc2ccccc2)ncc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N19 compound treatment 1030960.0 -46900.0 -0.23 1014760.0 -40000.0 -0.24 872160.0 -88789.375 -0.50854047239383 -0.5631 -0.9288 2070961 Maybridge1_003297 CCOC(=O)c1c[nH]c2ccc(cc2c1=O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N20 compound treatment 1168750.0 90900.0 0.44 1103620.0 48900.0 0.29 827360.0 -133589.375 -0.765132132862704 -0.0175 -0.0188 1226007 Maybridge1_003298 Nc1ccccc1C(=O)NC2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N21 compound treatment 1020170.0 -57700.0 -0.28 998720.0 -56000.0 -0.33 857780.0 -103169.375 -0.590901813410401 -0.6962 -0.9478 2070962 Maybridge1_003299 COc1cc(/C=N/NC(=O)CC#N)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N22 compound treatment 953380.0 -124000.0 -0.61 1055680.0 937.0 0.01 762990.0 -197959.375 -1.13381082001408 -1.0025 -0.7792 2070963 Maybridge1_003300 Clc1ccccc1/C=C/2\CCC/C(=C\c3ccccc3Cl)/C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N23 mock treatment 1137570.0 59700.0 0.29 1089250.0 34500.0 0.21 1139580.0 178630.625 1.02310555087819 0.8776 0.81 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 N24 mock treatment 950160.0 -128000.0 -0.62 1030690.0 -24100.0 -0.14 997090.0 36140.625 0.206995155784217 -0.3232 -0.4805 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O01 compound treatment 998790.0 -79100.0 -0.39 933310.0 -121000.0 -0.72 955410.0 -5539.375 -0.0317267283305753 -0.6582 -0.8032 1263209 Maybridge1_003301 CC(C)(C)c1nc(N)sc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O02 compound treatment 1098620.0 20800.0 0.1 1212850.0 158000.0 0.94 1004830.0 43880.625 0.251325947124152 0.7465 0.763 2070964 Maybridge1_003302 Cc1nn(C)c(C)c1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O03 compound treatment 1144860.0 67000.0 0.33 1039680.0 -15100.0 -0.09 929820.0 -31129.375 -0.178293259388577 0.0344 0.0897 2070965 Maybridge1_003303 Brc1cc(Br)cc(CSc2ccccn2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O04 compound treatment 1111770.0 33900.0 0.17 1173190.0 118000.0 0.7 998840.0 37890.625 0.217018267521282 0.6277 0.8309 1171047 Maybridge1_003304 Fc1ccc(cc1)C(=O)C2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O05 compound treatment 524500.0 -553000.0 -2.7 532260.0 -522000.0 -3.11 443950.0 -516999.375 -2.96111000206742 -5.0643 -0.9984 1441367 Maybridge1_003305 CC(C)(C)C(=O)c1sc2sc(C(=O)C(C)(C)C)c(N)c2c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O06 compound treatment 883070.0 -195000.0 -0.95 860980.0 -194000.0 -1.15 737220.0 -223729.375 -1.28140829970789 -1.9545 -0.9928 2070966 Maybridge1_003306 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1N2CCNCC2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O07 compound treatment 1080060.0 2220.0 0.01 1104720.0 50000.0 0.3 982880.0 21930.625 0.125607488479246 0.2504 0.7755 1985191 Maybridge1_003307 COC(=O)c1sccc1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O08 compound treatment 1320050.0 242000.0 1.18 1196660.0 142000.0 0.84 854790.0 -106159.375 -0.60802701574973 0.8194 0.5201 2070967 Maybridge1_003308 CS/C(=N\C#N)/NC1CCCCNC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O09 compound treatment 1186930.0 109000.0 0.53 1196170.0 141000.0 0.84 930820.0 -30129.375 -0.172565766967397 0.6936 0.6864 2070968 Maybridge1_003309 NC(=O)c1ccc(cc1)C(=N)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O10 compound treatment 1230250.0 152000.0 0.74 1222240.0 167000.0 1.0 1004220.0 43270.625 0.247832176747232 1.1481 0.9054 2070969 Maybridge1_003310 CN(C)/C=N/C(=O)C1CCN(CC1)c2cccc(F)c2C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O11 compound treatment 1201020.0 123000.0 0.6 1112750.0 58000.0 0.34 942930.0 -18019.375 -0.103205833746905 0.487 0.6945 2070970 Maybridge1_003311 CN(C)/C=C/1\C(=O)ON=C1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O12 compound treatment 1083860.0 6020.0 0.03 1018500.0 -36200.0 -0.22 893280.0 -67669.375 -0.387575832458503 -0.3312 -0.7453 2070971 Maybridge1_003312 CSC1=NS(=O)(=O)c2c(C)nn(C)c2S1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O13 compound treatment 953560.0 -124000.0 -0.61 1031010.0 -23700.0 -0.14 802980.0 -157969.375 -0.904768398091078 -0.9544 -0.8687 2070972 Maybridge1_003313 Cc1n[nH]cc1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O14 compound treatment 948510.0 -129000.0 -0.63 976210.0 -78500.0 -0.47 935520.0 -25429.375 -0.14564655258785 -0.7185 -0.8992 2070973 Maybridge1_003314 Cc1c(nnn1c2ccc(Cl)cc2Cl)c3ccnc(N)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O15 compound treatment 931220.0 -147000.0 -0.72 944170.0 -111000.0 -0.66 853930.0 -107019.375 -0.612952659231945 -1.1471 -0.998 1419671 Maybridge1_003315 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O16 compound treatment 932550.0 -145000.0 -0.71 951260.0 -103000.0 -0.62 824200.0 -136749.375 -0.783231008913634 -1.2173 -0.9953 2070974 Maybridge1_003316 Fc1ccc(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O17 compound treatment 1054580.0 -23300.0 -0.11 1120920.0 66200.0 0.39 950290.0 -10659.375 -0.061051489527018 0.1263 0.3051 2070975 Maybridge1_003317 [O-][N+](=O)c1cccnc1NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O18 compound treatment 1037240.0 -40600.0 -0.2 1066030.0 11300.0 0.07 878350.0 -82599.375 -0.473087294306724 -0.3489 -0.6744 2070976 Maybridge1_003318 OC(=O)c1cc(Br)cc(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O19 compound treatment 983930.0 -93900.0 -0.46 1031080.0 -23700.0 -0.14 821640.0 -139309.375 -0.797893389511855 -0.8068 -0.8665 2070977 Maybridge1_003319 CN(C)/C=N/C(=N\OCc1c(F)cccc1Cl)/c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O20 compound treatment 1030900.0 -46900.0 -0.23 934680.0 -120000.0 -0.71 727260.0 -233689.375 -1.33845412422285 -1.3174 -0.8587 2070978 Maybridge1_003320 Fc1cccc(Cl)c1/C=C/c2cnc3ccccc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O21 compound treatment 1045350.0 -32500.0 -0.16 1042050.0 -12700.0 -0.08 884960.0 -75989.375 -0.435228569402723 -0.3865 -0.8234 2070979 Maybridge1_003321 CS/C(=N/C#N)/NCCSC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O22 compound treatment 830480.0 -247000.0 -1.21 789770.0 -265000.0 -1.58 778190.0 -182759.375 -1.04675293521214 -2.2118 -0.9853 2070980 Maybridge1_003322 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCc2ccccc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O23 mock treatment 1204640.0 127000.0 0.62 1269280.0 215000.0 1.28 1190330.0 229380.625 1.31377579125309 1.8527 0.9584 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 O24 mock treatment 949520.0 -128000.0 -0.63 1074640.0 19900.0 0.12 889660.0 -71289.375 -0.408309355023176 -0.5294 -0.6989 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P01 compound treatment 982680.0 -95200.0 -0.46 1025770.0 -29000.0 -0.17 1006090.0 45140.625 0.258542587574839 -0.2186 -0.391 2070981 Maybridge1_003323 CSC(=NS(=O)(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P02 compound treatment 1090040.0 12200.0 0.06 1163280.0 109000.0 0.65 1005010.0 44060.625 0.252356895759964 0.5527 0.7947 1083128 Maybridge1_003324 Cc1ccccc1NC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P03 compound treatment 888830.0 -189000.0 -0.92 917360.0 -137000.0 -0.82 913010.0 -47939.375 -0.274572406988617 -1.1634 -0.921 2070982 Maybridge1_003325 CN(C)/C=N/C(=O)c1sc(C#N)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P04 compound treatment 1162660.0 84800.0 0.41 1104380.0 49600.0 0.3 978140.0 17190.625 0.0984591744028514 0.4665 0.9002 1735768 Maybridge1_003326 COc1ccccc1Nc2snc3sc(C(=O)c4ccc(C)cc4)c(N)c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P05 compound treatment 1147970.0 70100.0 0.34 1146000.0 91300.0 0.54 1124920.0 163970.625 0.939140511983686 1.0533 0.926 2070983 Maybridge1_003327 CC(=O)C1C(=O)CC(CC1=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P06 compound treatment 1152990.0 75100.0 0.37 1127040.0 72300.0 0.43 955680.0 -5269.375 -0.0301803053768566 0.4428 0.782 1585004 Maybridge1_003328 COc1cccc(NC(=S)C(C#N)C(=O)N2CCC(C)CC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P07 compound treatment 1118260.0 40400.0 0.2 1167700.0 113000.0 0.67 1021660.0 60710.625 0.347719644572615 0.7026 0.8988 2070984 Maybridge1_003329 Fc1ccccc1S(=O)(=O)CCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P08 compound treatment 1171060.0 93200.0 0.46 1158290.0 104000.0 0.62 856290.0 -104659.375 -0.59943577711796 0.2724 0.2801 1007678 Maybridge1_003330 Cc1ccc(cc1)C(=O)c2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P09 compound treatment 872960.0 -205000.0 -1.0 832660.0 -222000.0 -1.32 815640.0 -145309.375 -0.832258344038936 -1.8209 -0.9819 2070985 Maybridge1_003331 CC(=O)c1ccc(o1)c2ccc(F)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P10 compound treatment 872960.0 -205000.0 -1.0 854470.0 -200000.0 -1.19 758620.0 -202329.375 -1.15883996189463 -1.9346 -0.9972 1101361 Maybridge1_003332 N1C(Nc2ccccc12)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P11 compound treatment 1118120.0 40300.0 0.2 1137160.0 82400.0 0.49 992710.0 31760.625 0.181908738979447 0.5016 0.898 1282449 Maybridge1_003333 Nc1c(cnn1c2cc(Cl)cc(Cl)c2)c3nn[nH]n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P12 compound treatment 1041300.0 -36500.0 -0.18 941440.0 -113000.0 -0.67 948930.0 -12019.375 -0.0688408792198232 -0.5318 -0.7593 1612743 Maybridge1_003334 Cc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P13 compound treatment 747890.0 -330000.0 -1.61 729370.0 -325000.0 -1.93 670880.0 -290069.375 -1.66137014692899 -3.007 -0.9967 2070986 Maybridge1_003335 Cc1nc(COc2ccc(C#N)cc2)cs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P14 compound treatment 1206030.0 128000.0 0.63 1184680.0 130000.0 0.77 899710.0 -61239.375 -0.350748056190314 0.6052 0.5738 1029735 Maybridge1_003336 OC(=O)CC1SC(=N)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P15 compound treatment 1154850.0 77000.0 0.38 1165440.0 111000.0 0.66 951600.0 -9349.375 -0.0535484744552719 0.5664 0.7451 2070987 Maybridge1_003337 Clc1ccc(SCCS(=O)(=O)CCSc2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P16 compound treatment 1052230.0 -25600.0 -0.13 1041800.0 -12900.0 -0.08 898270.0 -62679.375 -0.358995645276814 -0.3239 -0.8352 2070988 Maybridge1_003338 O=C1OCCC/N=C(/c2ccccc2)\c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P17 compound treatment 1013600.0 -64200.0 -0.31 1020430.0 -34300.0 -0.2 814340.0 -146609.375 -0.839704084186471 -0.7838 -0.8526 2070989 Maybridge1_003339 Clc1ccc(/C=N/c2cc(Cl)cc(Cl)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P18 compound treatment 399930.0 -678000.0 -3.31 397390.0 -657000.0 -3.91 365760.0 -595189.375 -3.4089426344795 -6.1373 -0.9973 2070990 Maybridge1_003340 Cc1ccc(cc1)C(=O)CSC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P19 compound treatment 1029510.0 -48300.0 -0.24 1205800.0 151000.0 0.9 1005670.0 44720.625 0.256137040757943 0.5302 0.5503 1133957 Maybridge1_003341 OC(=O)C1CN(Cc2cccs2)C(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P20 compound treatment 1101770.0 23900.0 0.12 1084010.0 29300.0 0.17 987370.0 26420.625 0.151323929450345 0.2553 0.9875 1913964 Maybridge1_003342 Cc1ccc(cc1C)n2nnc3ccccc3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P21 compound treatment 1046930.0 -30900.0 -0.15 1013840.0 -40900.0 -0.24 926950.0 -33999.375 -0.194731162637365 -0.3401 -0.9821 2070991 Maybridge1_003343 COc1ccc(/C=N/NC(=O)CC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P22 compound treatment 371710.0 -706000.0 -3.45 408040.0 -647000.0 -3.85 392670.0 -568279.375 -3.25481581342554 -6.0913 -0.9976 2070992 Maybridge1_003344 O=C/1/C(=C/c2ccco2)/CCC\C1=C/c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P23 mock treatment 1127080.0 49200.0 0.24 1183730.0 129000.0 0.77 1105280.0 144330.625 0.826652560831706 1.059 0.9184 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.550 P24 mock treatment 971140.0 -107000.0 -0.52 978410.0 -76300.0 -0.45 959650.0 -1299.375 -0.00744216046477106 -0.5674 -0.8207 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A01 compound treatment 881370.0 -253000.0 -1.23 797950.0 -283000.0 -1.69 782250.0 -264192.8125 -1.51316233132404 -2.5596 -0.9922 2070993 Maybridge1_003345 O=C/1/C(=C/c2cccs2)/CCC\C1=C/c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A02 compound treatment 944960.0 -189000.0 -0.92 797530.0 -284000.0 -1.69 836320.0 -210122.8125 -1.20347681611082 -2.2029 -0.9706 2070994 Maybridge1_003346 CSC1=NCCN1C(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A03 compound treatment 901940.0 -232000.0 -1.13 813310.0 -268000.0 -1.59 876240.0 -170202.8125 -0.97483531865731 -2.138 -0.9781 2070995 Maybridge1_003347 Clc1ccccc1/C=C/2\CC/C(=C\c3ccccc3Cl)/C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A04 compound treatment 505650.0 -628000.0 -3.07 439300.0 -642000.0 -3.82 382270.0 -664172.8125 -3.80404474994771 -6.1734 -0.9952 2070996 Maybridge1_003348 Clc1ccc(cc1)c2csc(Nc3ccccc3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A05 compound treatment 168640.0 -965000.0 -4.72 217330.0 -864000.0 -5.14 150100.0 -896342.8125 -5.13379666537312 -8.6539 -0.9992 2070997 Maybridge1_003349 CN1C/C(=C\C=C\c2ccccc2)/C(=O)\C(=C\C=C\c3ccccc3)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A06 compound treatment 990170.0 -144000.0 -0.7 912520.0 -169000.0 -1.0 891720.0 -154722.8125 -0.88617373597744 -1.4973 -0.9899 2070998 Maybridge1_003350 Cc1cc(C)c(CS/C(=N/N)/N)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A07 compound treatment 676700.0 -457000.0 -2.23 634690.0 -447000.0 -2.66 621410.0 -425032.8125 -2.43437221234667 -4.2293 -0.9975 2070999 Maybridge1_003351 Cc1ccc(CSC2=NCCN2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A08 compound treatment 23000.0 -1110000.0 -5.43 20090.0 -1060000.0 -6.31 23320.0 -1023122.8125 -5.85992815453035 -10.1611 -0.9981 2071000 Maybridge1_003352 Cc1c(C)c(C)c(CSC2=NCCCN2C3CCCCC3)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A09 compound treatment 1021460.0 -113000.0 -0.55 952160.0 -129000.0 -0.77 1063530.0 17087.1875 0.0978667369055356 -0.7048 -0.7418 2071001 Maybridge1_003353 C(SC1=NCCCN1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A10 compound treatment 875610.0 -258000.0 -1.26 915690.0 -166000.0 -0.99 920600.0 -125842.8125 -0.720763754853755 -1.7141 -0.9759 1664303 Maybridge1_003354 CC(=O)Nc1ccc(cc1)C(=C(C#N)C#N)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A11 compound treatment 24870.0 -1110000.0 -5.42 22850.0 -1060000.0 -6.29 27840.0 -1018602.8125 -5.83403988878662 -10.1314 -0.9981 2071002 Maybridge1_003355 Cc1c(C)c(C)c(CSC2=NCCN2Cc3ccccc3)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A12 compound treatment 932750.0 -201000.0 -0.98 825670.0 -256000.0 -1.52 954850.0 -91592.8125 -0.524597139428332 -1.7487 -0.9275 2071003 Maybridge1_003356 Clc1ccc(cc1)C2=NC(N=C(S2)c3ccc(Cl)cc3)c4ccc(Cl)c(Cl)c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A13 compound treatment 874050.0 -260000.0 -1.27 767710.0 -314000.0 -1.87 729870.0 -316572.8125 -1.81316838434546 -2.8573 -0.987 2071004 Maybridge1_003357 CNC(=S)N/N=C(\C)/c1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A14 compound treatment 711920.0 -422000.0 -2.06 765320.0 -316000.0 -1.88 720020.0 -326422.8125 -1.86958418469409 -3.3554 -0.999 2071005 Maybridge1_003358 Cc1ccc(CSC2=NCN(CN2)C(C)(C)CC(C)(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A15 compound treatment 667300.0 -467000.0 -2.28 588030.0 -493000.0 -2.93 606690.0 -439752.8125 -2.51868090078644 -4.4647 -0.9946 2071006 Maybridge1_003359 Clc1ccc2OC(Nc2c1)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A16 compound treatment 613280.0 -521000.0 -2.54 617290.0 -464000.0 -2.76 686340.0 -360102.8125 -2.06248612943944 -4.2532 -0.993 2071007 Maybridge1_003360 CCOC(=O)c1sc2ccccc2c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A17 compound treatment 767730.0 -366000.0 -1.79 820400.0 -261000.0 -1.55 878370.0 -168072.8125 -0.962635759800196 -2.4852 -0.9719 1345383 Maybridge1_003361 N1C(c2ccccc2)n3c(nc4ccccc34)-c5ccccc15 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A18 compound treatment 972480.0 -162000.0 -0.79 875320.0 -206000.0 -1.23 1067940.0 21497.1875 0.12312497848294 -1.0922 -0.7466 2071008 Maybridge1_003362 FC(F)(F)c1nn2cc(nc2s1)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A19 compound treatment 789610.0 -344000.0 -1.68 889600.0 -192000.0 -1.14 805200.0 -241242.8125 -1.38171638025795 -2.4279 -0.9877 1222161 Maybridge1_003363 N1C(Oc2ccccc12)c3cccc4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A20 compound treatment 840920.0 -293000.0 -1.43 819950.0 -261000.0 -1.55 871460.0 -174982.8125 -1.00221273243055 -2.3032 -0.9845 2071009 Maybridge1_003364 Clc1cc(Cl)c(Cl)c(I)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A21 compound treatment 493280.0 -641000.0 -3.13 513770.0 -568000.0 -3.38 542440.0 -504002.8125 -2.88667228884727 -5.423 -0.998 2071010 Maybridge1_003365 CCN1CNC(=NC1)SCc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A22 compound treatment 859730.0 -274000.0 -1.34 860560.0 -221000.0 -1.31 965600.0 -80842.8125 -0.463026595900645 -1.7994 -0.931 1879466 Maybridge1_003366 [O-][N+](=O)c1ccc(cc1)C(=O)NCc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A23 mock treatment 962880.0 -171000.0 -0.84 859430.0 -222000.0 -1.32 968270.0 -78172.8125 -0.447734191136093 -1.5035 -0.9249 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 A24 mock treatment 936890.0 -197000.0 -0.96 841600.0 -240000.0 -1.43 976190.0 -70252.8125 -0.402372451160346 -1.6118 -0.912 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B01 compound treatment 1102810.0 -31300.0 -0.15 973350.0 -108000.0 -0.64 938400.0 -108042.8125 -0.618814389756747 -0.8164 -0.9021 2071011 Maybridge1_003367 Clc1ccccc1CSC2=Nc3ccccc3C(=O)NN2c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B02 compound treatment 678680.0 -455000.0 -2.23 1089720.0 8350.0 0.05 1003890.0 -42552.8125 -0.243720911093653 -1.3967 -0.6238 1510166 Maybridge1_003368 Clc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B03 compound treatment 1100690.0 -33400.0 -0.16 1124320.0 42900.0 0.26 1093010.0 46567.1875 0.266713213481929 0.2072 0.5132 2071012 Maybridge1_003369 [O-][N+](=O)c1ccc(SC2=NCCN2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B04 compound treatment 807230.0 -327000.0 -1.6 784480.0 -297000.0 -1.77 770320.0 -276122.8125 -1.58149131590872 -2.8544 -0.9987 1291880 Maybridge1_003370 CCOC(=O)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B05 compound treatment 1090080.0 -44000.0 -0.22 1009070.0 -72300.0 -0.43 977470.0 -68972.8125 -0.395041260861235 -0.6005 -0.965 1085749 Maybridge1_003371 CCOC(=O)CSc1ccc(cc1Cl)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B06 compound treatment 974720.0 -159000.0 -0.78 870820.0 -211000.0 -1.25 916320.0 -130122.8125 -0.745277422416406 -1.6027 -0.9701 1454539 Maybridge1_003372 Cc1onc(c1C(=O)Nc2ccc(F)c(F)c2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B07 compound treatment 664800.0 -469000.0 -2.29 646090.0 -435000.0 -2.59 701790.0 -344652.8125 -1.9739963715322 -3.9579 -0.994 2071013 Maybridge1_003373 CC(C)c1ccc(/N=C/c2cc(Br)ccc2O)c(Br)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B08 compound treatment 1034780.0 -99300.0 -0.49 859230.0 -222000.0 -1.32 955360.0 -91082.8125 -0.52167611829353 -1.344 -0.8955 2071014 Maybridge1_003374 NS(=O)(=O)c1ccc(Sc2ccccn2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B09 compound treatment 1000410.0 -134000.0 -0.65 921150.0 -160000.0 -0.95 1040420.0 -6022.8125 -0.0344956129479396 -0.9471 -0.8195 1658093 Maybridge1_003375 COc1ccc(CCNC2(CCCCC2)C#N)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B10 compound treatment 655360.0 -479000.0 -2.34 644410.0 -437000.0 -2.6 715890.0 -330552.8125 -1.89323872839356 -3.9437 -0.9919 2071015 Maybridge1_003376 ClC(Cl)(Cl)C(=O)N1CCc2ccccc2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B11 compound treatment 1026320.0 -108000.0 -0.53 1010020.0 -71400.0 -0.42 1118400.0 71957.1875 0.412134246055695 -0.311 -0.3928 1004134 Maybridge1_003377 CCOC(=O)NCc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B12 compound treatment 1053410.0 -80700.0 -0.39 1084640.0 3270.0 0.02 997080.0 -49362.8125 -0.282725134481891 -0.3796 -0.7819 2071016 Maybridge1_003378 Cc1ccc(nc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B13 compound treatment 965440.0 -169000.0 -0.82 1048570.0 -32800.0 -0.2 1036800.0 -9642.8125 -0.055229135512612 -0.6203 -0.7309 1410553 Maybridge1_003379 CC(C)N(CCC#N)C(=O)c1c(C)onc1c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B14 compound treatment 982160.0 -152000.0 -0.74 895810.0 -186000.0 -1.1 1012800.0 -33642.8125 -0.192688953620938 -1.1769 -0.8758 1690979 Maybridge1_003380 Cc1cccc(NC(=S)NCc2ccncc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B15 compound treatment 1015960.0 -118000.0 -0.58 909210.0 -172000.0 -1.02 1053200.0 6757.1875 0.0387017401947438 -0.902 -0.767 2071017 Maybridge1_003381 O=C/1C2CCN(CC2)\C1=C/c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B16 compound treatment 981720.0 -152000.0 -0.74 922500.0 -159000.0 -0.94 1121950.0 75507.1875 0.432466844150885 -0.7256 -0.5677 1200805 Maybridge1_003382 COc1ccccc1NC(=S)NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B17 compound treatment 119520.0 -1010000.0 -4.96 136910.0 -944000.0 -5.62 125440.0 -921002.8125 -5.27503662847943 -9.1501 -0.9987 2071018 Maybridge1_003383 C=C1S/C(=N/c2ccc(cc2)S(=O)(=O)N3CCCCC3)/NC41CCCCC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B18 compound treatment 985130.0 -149000.0 -0.73 970630.0 -111000.0 -0.66 960510.0 -85932.8125 -0.492179532324452 -1.0846 -0.9878 2071019 Maybridge1_003384 Cc1ccccc1NC(=S)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B19 compound treatment 1026640.0 -107000.0 -0.53 1028020.0 -53400.0 -0.32 977180.0 -69262.8125 -0.396702233663377 -0.7153 -0.9792 2071020 Maybridge1_003385 C[C@@]1(CCC2C(CCC3C[C@H](O)CC[C@@]32C)C1/C=C\4/Nc5ccccc5C4=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B20 compound treatment 979750.0 -154000.0 -0.75 934720.0 -147000.0 -0.87 1025340.0 -21102.8125 -0.120866198659337 -1.0087 -0.8701 2071021 Maybridge1_003386 COc1cccc(NC(=S)N2CC(C)OC(C)C2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B21 compound treatment 779790.0 -354000.0 -1.73 812210.0 -269000.0 -1.6 903790.0 -142652.8125 -0.817042902453795 -2.3953 -0.9599 1162137 Maybridge1_003387 Clc1ccc(cc1Cl)C(NCc2ccccc2)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B22 compound treatment 1001120.0 -133000.0 -0.65 900100.0 -181000.0 -1.08 911120.0 -135322.8125 -0.775060383006544 -1.4449 -0.9776 2071022 Maybridge1_003388 Cc1ccc(NC(=S)NCc2ccncc2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B23 mock treatment 1080160.0 -53900.0 -0.26 967210.0 -114000.0 -0.68 1107570.0 61127.1875 0.350105503134313 -0.342 -0.4232 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 B24 mock treatment 1027260.0 -107000.0 -0.52 1056380.0 -25000.0 -0.15 991460.0 -54982.8125 -0.314913641888924 -0.569 -0.9068 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C01 compound treatment 1026040.0 -108000.0 -0.53 945440.0 -136000.0 -0.81 982470.0 -63972.8125 -0.366403798755334 -0.983 -0.952 2071023 Maybridge1_003389 O=C/1/C(=C/c2ccccc2)/CC\C1=C/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C02 compound treatment 711080.0 -423000.0 -2.07 705770.0 -376000.0 -2.23 815120.0 -231322.8125 -1.32489965543985 -3.2477 -0.9785 2071024 Maybridge1_003390 Clc1ccc(cc1)c2csc(n2)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C03 compound treatment 697660.0 -436000.0 -2.13 740400.0 -341000.0 -2.03 752050.0 -294392.8125 -1.68613260244368 -3.3753 -0.9953 2071025 Maybridge1_003391 CN(C)c1ccc(/C=C/2\CCC/C(=C\c3ccc(cc3)N(C)C)/C2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C04 compound treatment 926050.0 -208000.0 -1.02 909940.0 -171000.0 -1.02 943890.0 -102552.8125 -0.587370456364467 -1.5146 -0.9741 2071026 Maybridge1_003392 NC(=S)Cc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C05 compound treatment 984930.0 -149000.0 -0.73 842410.0 -239000.0 -1.42 1082130.0 35687.1875 0.204398095939488 -1.1232 -0.6976 1433637 Maybridge1_003393 CNc1ccc(Cl)cc1C(=O)NCCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C06 compound treatment 1058640.0 -75500.0 -0.37 1012320.0 -69100.0 -0.41 1106880.0 60437.1875 0.346153533363699 -0.2501 -0.3839 1101362 Maybridge1_003394 CC(O)CN1CNC(=S)NC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C07 compound treatment 846400.0 -288000.0 -1.41 878400.0 -203000.0 -1.21 787420.0 -259022.8125 -1.48355119550654 -2.3649 -0.9964 1018871 Maybridge1_003395 C(SC1=NCCN1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C08 compound treatment 672840.0 -461000.0 -2.25 631470.0 -450000.0 -2.68 714620.0 -331822.8125 -1.90051264376846 -3.943 -0.9905 2071027 Maybridge1_003396 Clc1cccc(Cl)c1CSC2=NCCCN2C3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C09 compound treatment 614720.0 -519000.0 -2.54 646660.0 -435000.0 -2.59 631300.0 -415142.8125 -2.3777273123012 -4.3303 -0.9994 2071028 Maybridge1_003397 CC1CNC(=N1)SCc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C10 compound treatment 1211070.0 77000.0 0.38 1040410.0 -41000.0 -0.24 1311270.0 264827.1875 1.51679570932873 0.9522 0.6021 2071029 Maybridge1_003398 COc1ccc(cc1OC)C2N=C(SC(=N2)c3ccc(Cl)cc3)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C11 compound treatment 881120.0 -253000.0 -1.24 772600.0 -309000.0 -1.84 781700.0 -264742.8125 -1.51631245215569 -2.6491 -0.9874 2071030 Maybridge1_003399 Cc1c(C)c(C)c(CSc2nc3ccccc3[nH]2)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C12 compound treatment 615840.0 -518000.0 -2.53 667110.0 -414000.0 -2.46 630880.0 -415562.8125 -2.38013285911809 -4.2584 -0.9997 1734920 Maybridge1_003400 Brc1ccc(cc1)c2csc(=N)n2c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C13 compound treatment 38080.0 -1100000.0 -5.35 969850.0 -112000.0 -0.66 1041920.0 -4522.8125 -0.0259043743161692 -3.4895 -0.6467 2071031 Maybridge1_003401 CNC(=S)N/N=C(\C)/c1cccc(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C14 compound treatment 1024580.0 -110000.0 -0.54 1101150.0 19800.0 0.12 1112500.0 66057.1875 0.378342040770732 -0.0226 -0.0339 2071032 Maybridge1_003402 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2c(nc3ccccc3c2=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C15 compound treatment 672550.0 -462000.0 -2.26 699730.0 -382000.0 -2.27 706480.0 -339962.8125 -1.94713443207687 -3.7364 -0.9976 2071033 Maybridge1_003403 COc1ccc(cc1)C2Nc3cc(Cl)ccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C16 compound treatment 877700.0 -256000.0 -1.25 913680.0 -168000.0 -1.0 976690.0 -69752.8125 -0.399508704949756 -1.5296 -0.9269 2071034 Maybridge1_003404 Clc1ccc(cc1)C(=N)NCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C17 compound treatment 754120.0 -380000.0 -1.86 692420.0 -389000.0 -2.31 665560.0 -380882.8125 -2.18150342195156 -3.6667 -0.9959 2071035 Maybridge1_003405 CN(C)c1ccc(C2Nc3ccccc3O2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C18 compound treatment 1098110.0 -36000.0 -0.18 1022180.0 -59200.0 -0.35 980400.0 -66042.8125 -0.378259708067177 -0.5231 -0.9585 2071036 Maybridge1_003406 CCOC(=O)c1c(NC(=O)COc2ccccc2)sc3CCCCc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C19 compound treatment 879230.0 -255000.0 -1.25 859640.0 -222000.0 -1.32 921670.0 -124772.8125 -0.714635337963092 -1.8928 -0.971 1150673 Maybridge1_003407 COc1cc(cc(OC)c1OC)C2Nc3ccccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C20 compound treatment 1018530.0 -116000.0 -0.56 1023910.0 -57500.0 -0.34 1032810.0 -13632.8125 -0.0780818302731211 -0.5684 -0.8552 1057038 Maybridge1_003408 CNc1ccccc1C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C21 compound treatment 521380.0 -613000.0 -2.99 556640.0 -525000.0 -3.12 562620.0 -483822.8125 -2.77109149178785 -5.1298 -0.9988 2071037 Maybridge1_003409 CCN1CNC(=NC1)SCc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C22 compound treatment 866430.0 -268000.0 -1.31 945560.0 -136000.0 -0.81 914520.0 -131922.8125 -0.755586908774531 -1.6576 -0.9678 2071038 Maybridge1_003410 [O-][N+](=O)c1ccc(N2CCOCC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C23 mock treatment 1080730.0 -53400.0 -0.26 1051520.0 -29900.0 -0.18 971090.0 -75352.8125 -0.431582662508365 -0.5022 -0.9395 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 C24 mock treatment 980860.0 -153000.0 -0.75 931430.0 -150000.0 -0.89 1014280.0 -32162.8125 -0.184212264837591 -1.0534 -0.8936 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D01 compound treatment 1033720.0 -100000.0 -0.49 1017920.0 -63500.0 -0.38 1026780.0 -19662.8125 -0.112618609572838 -0.566 -0.8999 1049869 Maybridge1_003411 OC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D02 compound treatment 979710.0 -154000.0 -0.75 894330.0 -187000.0 -1.11 972650.0 -73792.8125 -0.422647774331324 -1.3217 -0.9382 2071039 Maybridge1_003412 OC1=NC(Nc2ccccc12)c3cccc(c3)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D03 compound treatment 1127090.0 -7010.0 -0.03 966520.0 -115000.0 -0.68 1096860.0 50417.1875 0.288764059303473 -0.2474 -0.3332 2071040 Maybridge1_003413 [O-][N+](=O)c1ccc(Sc2ccccc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D04 compound treatment 788660.0 -345000.0 -1.69 804800.0 -277000.0 -1.64 762590.0 -283852.8125 -1.62576483232444 -2.8626 -0.9999 1922174 Maybridge1_003414 Oc1ccccc1/C=N/c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D05 compound treatment 858020.0 -276000.0 -1.35 806020.0 -275000.0 -1.64 808820.0 -237622.8125 -1.36098285769328 -2.5099 -0.9958 2071041 Maybridge1_003415 Cc1ccc(C(=O)NNC(=O)c2ccncc2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D06 compound treatment 845600.0 -288000.0 -1.41 724000.0 -357000.0 -2.13 670670.0 -375772.8125 -2.15223593567933 -3.2833 -0.9839 1180385 Maybridge1_003416 Cc1c(C)c(C)c(CSCC(=O)NN)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D07 compound treatment 744980.0 -389000.0 -1.9 789890.0 -291000.0 -1.73 900430.0 -146012.8125 -0.83628727698896 -2.5812 -0.9542 1484448 Maybridge1_003417 Clc1ccc2oc(cc2c1)c3csc(NCC=C)n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D08 compound treatment 934030.0 -200000.0 -0.98 1007090.0 -74300.0 -0.44 1155540.0 109097.1875 0.624853314578329 -0.4586 -0.3694 2071042 Maybridge1_003418 [O-][N+](=O)c1cc(ccc1Sc2ccccn2)C(=O)N3CCC=CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D09 compound treatment 788530.0 -346000.0 -1.69 789440.0 -292000.0 -1.74 842720.0 -203722.8125 -1.16682086461527 -2.6507 -0.9861 1675509 Maybridge1_003419 CC(C)c1ccc(NC2(CCCCC2)C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D10 compound treatment 959390.0 -175000.0 -0.85 851730.0 -230000.0 -1.37 942400.0 -104042.8125 -0.595904420072026 -1.6253 -0.9465 2071043 Maybridge1_003420 ClC(Cl)(Cl)C(=O)N1CCN2C(=O)c3ccccc3C12c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D11 compound treatment 654670.0 -479000.0 -2.34 762780.0 -319000.0 -1.89 738140.0 -308302.8125 -1.7658020220223 -3.4657 -0.9925 2071044 Maybridge1_003421 Nc1ccc(Cl)cc1/C(=N/O)/c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D12 compound treatment 1495230.0 361000.0 1.76 977540.0 -104000.0 -0.62 1156490.0 110047.1875 0.63029443237845 1.0261 0.5201 2071045 Maybridge1_003422 O=C1C2C3CC(C=C3)C2C(=O)N1c4cccc(n4)N5C(=O)C6C7CC(C=C7)C6C5=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D13 compound treatment 1170340.0 36200.0 0.18 1316420.0 235000.0 1.4 1144480.0 98037.1875 0.561507248400075 1.2334 0.8132 1204368 Maybridge1_003423 COC(=O)c1ccccc1NC(=O)c2c(C)onc2c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D14 compound treatment 983320.0 -151000.0 -0.74 1005460.0 -75900.0 -0.45 1143680.0 97237.1875 0.556925254463131 -0.3644 -0.3545 2071046 Maybridge1_003424 Cc1ccc(NC(=S)NCc2ccncc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D15 compound treatment 1017460.0 -117000.0 -0.57 922000.0 -159000.0 -0.95 865470.0 -180972.8125 -1.03652041203342 -1.4746 -0.9729 2071047 Maybridge1_003425 COc1ccc(/C=C\2/N3CCC(CC3)C2=O)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D16 compound treatment 1078850.0 -55200.0 -0.27 1141080.0 59700.0 0.36 1062260.0 15817.1875 0.0905928215306367 0.1015 0.2229 2071048 Maybridge1_003426 Clc1ccccc1NC(=S)NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D17 compound treatment 825760.0 -308000.0 -1.51 738460.0 -343000.0 -2.04 763840.0 -282602.8125 -1.61860546679797 -2.9816 -0.9912 2071049 Maybridge1_003427 COc1cccc(/N=C\2/NC(C)(C)C(=C)S2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D18 compound treatment 1192510.0 58400.0 0.29 973450.0 -108000.0 -0.64 1015070.0 -31372.8125 -0.179687545824858 -0.3095 -0.4269 2071050 Maybridge1_003428 COc1ccc(NC(=S)N2CCOCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D19 compound treatment 564570.0 -570000.0 -2.78 498800.0 -583000.0 -3.46 644600.0 -401842.8125 -2.3015516630995 -4.9355 -0.9863 2071051 Maybridge1_003429 C[C@@]1(CCC2C(CCC3CC=CC[C@@]32C)C1/C=C\4/Nc5ccccc5C4=O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D20 compound treatment 953820.0 -180000.0 -0.88 944340.0 -137000.0 -0.81 962370.0 -84072.8125 -0.481526396421057 -1.257 -0.9722 2071052 Maybridge1_003430 COc1ccccc1NC(=S)N2CC(C)OC(C)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D21 compound treatment 869150.0 -265000.0 -1.29 829360.0 -252000.0 -1.5 924690.0 -121752.8125 -0.697338310851128 -2.0152 -0.9599 1698522 Maybridge1_003431 COc1ccc(CCNC(C#N)c2ccc(Cl)c(Cl)c2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D22 compound treatment 938830.0 -195000.0 -0.95 930180.0 -151000.0 -0.9 959460.0 -86982.8125 -0.498193399366691 -1.3575 -0.968 2071053 Maybridge1_003432 Cc1cccc(C)c1NC(=S)NCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D23 mock treatment 1023840.0 -110000.0 -0.54 1021820.0 -59600.0 -0.35 1048700.0 2257.1875 0.0129280242994328 -0.508 -0.7879 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 D24 mock treatment 1108670.0 -25400.0 -0.12 1066490.0 -14900.0 -0.09 1154260.0 107817.1875 0.617522124279218 0.2337 0.3674 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E01 compound treatment 1146140.0 12000.0 0.06 1188000.0 107000.0 0.63 1157560.0 111117.1875 0.636422849269113 0.7675 0.8525 2071054 Maybridge1_003433 COc1cc(C#N)c(OC)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E02 compound treatment 1228550.0 94500.0 0.46 988060.0 -93300.0 -0.55 1127010.0 80567.1875 0.461447955802057 0.2125 0.248 2071055 Maybridge1_003434 S=C1NCN(Cc2ccccc2)CN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E03 compound treatment 117570.0 -1020000.0 -4.97 120830.0 -961000.0 -5.71 109120.0 -937322.8125 -5.36850930479309 -9.2647 -0.9984 2071056 Maybridge1_003435 CN1C/C(=C\c2ccc(Cl)cc2)/C(=O)\C(=C\c3ccc(Cl)cc3)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E04 compound treatment 1025930.0 -108000.0 -0.53 968640.0 -113000.0 -0.67 1052480.0 6037.1875 0.034577945651494 -0.6722 -0.7868 2071057 Maybridge1_003436 COc1ccc(CC(=S)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E05 compound treatment 967890.0 -166000.0 -0.81 914780.0 -167000.0 -0.99 1040350.0 -6092.8125 -0.0348965374174222 -1.0609 -0.8279 1643078 Maybridge1_003437 CNc1ccccc1C(=O)NCCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E06 compound treatment 1082890.0 -51200.0 -0.25 905050.0 -176000.0 -1.05 1046140.0 -302.8125 -0.00173435629878864 -0.7508 -0.6965 1305363 Maybridge1_003438 Nc1nc(cs1)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E07 compound treatment 528870.0 -605000.0 -2.96 556180.0 -525000.0 -3.12 586240.0 -460202.8125 -2.63580812079958 -5.0321 -0.9976 2071058 Maybridge1_003439 Clc1ccc(CSC2=NCCN2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E08 compound treatment 958400.0 -176000.0 -0.86 942770.0 -139000.0 -0.82 956120.0 -90322.8125 -0.517323224053433 -1.2701 -0.9788 2071059 Maybridge1_003440 N#Cc1ccc(CSC2=NCCCN2C3CCCCC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E09 compound treatment 473180.0 -661000.0 -3.23 483380.0 -598000.0 -3.56 445880.0 -600562.8125 -3.43971895703644 -5.9033 -0.9992 2071060 Maybridge1_003441 Cc1ccc(CSc2nc3ccccc3[nH]2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E10 compound treatment 1110400.0 -23700.0 -0.12 1155790.0 74400.0 0.44 1022310.0 -24132.8125 -0.138220500695514 0.1088 0.2278 2071061 Maybridge1_003442 COc1cc(cc(OC)c1OC)C2N=C(SC(=N2)c3ccc(Cl)cc3)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E11 compound treatment 884160.0 -250000.0 -1.22 875920.0 -205000.0 -1.22 833130.0 -213312.8125 -1.22174751693439 -2.1158 -1.0 2071062 Maybridge1_003443 CN(C)c1ccc(cc1)C2NN=C(N2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E12 compound treatment 1007540.0 -127000.0 -0.62 1173600.0 92200.0 0.55 1209930.0 163487.1875 0.936371627366322 0.5003 0.4005 1055541 Maybridge1_003444 FC(F)(F)c1nc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E13 compound treatment 1243760.0 110000.0 0.54 1277220.0 196000.0 1.16 1130460.0 84017.1875 0.481207804655129 1.2596 0.9199 1922670 Maybridge1_003445 Nc1ccccc1C(=O)N/N=C/c2cccc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E14 compound treatment 1139050.0 4950.0 0.02 1108070.0 26700.0 0.16 1082120.0 35677.1875 0.204340821015276 0.2236 0.8604 1085424 Maybridge1_003446 OC(=O)c1ccccc1NC(=O)COc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E15 compound treatment 1009840.0 -124000.0 -0.61 1028410.0 -53000.0 -0.31 1098180.0 51737.1875 0.296324349299431 -0.3613 -0.4847 2071063 Maybridge1_003447 COc1ccc(OC)c(c1)/C(=N/O)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E16 compound treatment 1040290.0 -93800.0 -0.46 1052450.0 -28900.0 -0.17 1035140.0 -11302.8125 -0.0647367729317712 -0.4013 -0.8127 2071064 Maybridge1_003448 Nc1nnc(s1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E17 compound treatment 634770.0 -499000.0 -2.44 623220.0 -458000.0 -2.72 615430.0 -431012.8125 -2.46862261702533 -4.4067 -0.9987 1267546 Maybridge1_003449 CN(C)c1ccc(C2Nc3cc(Cl)ccc3O2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E18 compound treatment 834510.0 -300000.0 -1.46 740330.0 -341000.0 -2.03 737200.0 -309242.8125 -1.77118586489821 -3.0386 -0.9915 2071065 Maybridge1_003450 NC(=S)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E19 compound treatment 1062920.0 -71200.0 -0.35 1043160.0 -38200.0 -0.23 1081530.0 35087.1875 0.20096160048678 -0.2159 -0.468 1585575 Maybridge1_003451 CN(CCC#N)c1ccc(cc1)C2Nc3ccccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E20 compound treatment 1116400.0 -17700.0 -0.09 1020570.0 -60800.0 -0.36 1023680.0 -22762.8125 -0.130373836078497 -0.3339 -0.8476 1334251 Maybridge1_003452 Clc1ccccc1C(=O)NCc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E21 compound treatment 1054350.0 -79700.0 -0.39 1030400.0 -51000.0 -0.3 984820.0 -61622.8125 -0.352944191565561 -0.6037 -0.9949 2071066 Maybridge1_003453 COCCCN1CNC(=S)NC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E22 compound treatment 949600.0 -184000.0 -0.9 1136710.0 55300.0 0.33 1041800.0 -4642.8125 -0.0265916734067108 -0.3458 -0.3602 1726130 Maybridge1_003454 Nc1ccc(N2CCOCC2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E23 mock treatment 1163750.0 29700.0 0.14 1108580.0 27200.0 0.16 1132010.0 85567.1875 0.490085417907958 0.46 0.8581 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 E24 mock treatment 1037720.0 -96400.0 -0.47 1265490.0 184000.0 1.09 1046400.0 -42.8125 -2.45208269281779E-4 0.3601 0.3022 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F01 compound treatment 1029010.0 -105000.0 -0.51 1044810.0 -36600.0 -0.22 998080.0 -48362.8125 -0.276997642060711 -0.5819 -0.9346 2071067 Maybridge1_003455 Cc1nnc(NC(=S)N)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F02 compound treatment 586300.0 -548000.0 -2.68 590400.0 -491000.0 -2.92 608800.0 -437642.8125 -2.50659589177775 -4.6781 -0.998 1079948 Maybridge1_003456 Clc1ccccc1C2NC(=O)c3ccccc3N2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F03 compound treatment 1040730.0 -93400.0 -0.46 964440.0 -117000.0 -0.7 1113990.0 67547.1875 0.38687600447829 -0.4415 -0.4813 2071068 Maybridge1_003457 OC(=O)c1cc(ccc1Cl)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F04 compound treatment 246640.0 -887000.0 -4.34 250180.0 -831000.0 -4.94 257090.0 -789352.8125 -4.52101225123105 -7.9673 -0.9985 1910594 Maybridge1_003458 Oc1c(Br)cc(Br)cc1/C=N/c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F05 compound treatment 929650.0 -204000.0 -1.0 1006680.0 -74700.0 -0.44 1034520.0 -11922.8125 -0.0682878182329029 -0.8726 -0.7966 2071069 Maybridge1_003459 FC(F)(F)c1cccc(c1)C(=O)NNC(=O)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F06 compound treatment 1072370.0 -61700.0 -0.3 1206100.0 125000.0 0.74 1122660.0 76217.1875 0.436533363769923 0.5061 0.555 2071070 Maybridge1_003460 NNC(=O)CSc1ccccc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F07 compound treatment 1076820.0 -57300.0 -0.28 1258300.0 177000.0 1.05 1045050.0 -1392.8125 -0.00797732303787509 0.4413 0.4053 2071071 Maybridge1_003461 FC(F)(F)c1cc(cc(c1)S(=O)(=O)c2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F08 compound treatment 643150.0 -491000.0 -2.4 733400.0 -348000.0 -2.07 717610.0 -328832.8125 -1.88338744142913 -3.6669 -0.995 2071072 Maybridge1_003462 [O-][N+](=O)c1ccc(NC(=O)c2ccc(Sc3ccc(Cl)cc3)c(c2)[N+](=O)[O-])nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F09 compound treatment 27540.0 -1110000.0 -5.41 30080.0 -1050000.0 -6.25 25440.0 -1021002.8125 -5.84778587059745 -10.107 -0.9983 1049326 Maybridge1_003463 Fc1ccc(cc1)C(=O)CCN2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F10 compound treatment 1012430.0 -122000.0 -0.59 1237550.0 156000.0 0.93 1037520.0 -8922.8125 -0.0511053409693622 0.1635 0.1481 2071073 Maybridge1_003464 C/C(=N\O)/c1ccc(Cl)c(NC(=O)c2c(C)onc2c3ccccc3Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F11 compound treatment 900070.0 -234000.0 -1.14 860820.0 -221000.0 -1.31 865920.0 -180522.8125 -1.03394304044389 -2.0143 -0.9952 2071074 Maybridge1_003465 [O-][N+](=O)c1ccc(N/N=C/2\CCCCC2CCC#N)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F12 compound treatment 1155300.0 21200.0 0.1 1061400.0 -20000.0 -0.12 1226490.0 180047.1875 1.03121890186107 0.5866 0.5623 1613737 Maybridge1_003466 COc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F13 compound treatment 649480.0 -485000.0 -2.37 623380.0 -458000.0 -2.72 559280.0 -487162.8125 -2.7902213164746 -4.5504 -0.9975 1056544 Maybridge1_003467 CCOC(=O)c1c(N)sc2CCCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F14 compound treatment 1266590.0 132000.0 0.65 1041090.0 -40300.0 -0.24 1012160.0 -34282.8125 -0.196354548770493 0.1221 0.1701 1138910 Maybridge1_003468 COc1ccc(NC(=S)NCc2ccncc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F15 compound treatment 969540.0 -165000.0 -0.8 886990.0 -194000.0 -1.16 816880.0 -229562.8125 -1.31481926877857 -1.8907 -0.9814 2071075 Maybridge1_003469 O=C/1C2CCN(CC2)\C1=C\c3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F16 compound treatment 1121630.0 -12500.0 -0.06 1143040.0 61700.0 0.37 783680.0 -262762.8125 -1.50497201716175 -0.6923 -0.4466 2071076 Maybridge1_003470 FC(F)(F)c1cccc(NC(=S)NCc2cccnc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F17 compound treatment 638900.0 -495000.0 -2.42 609410.0 -472000.0 -2.81 561060.0 -485382.8125 -2.7800263799649 -4.6223 -0.9978 2071077 Maybridge1_003471 Cc1ccc(/N=C\2/NC(C)(C)C(=C)S2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F18 compound treatment 940120.0 -194000.0 -0.95 1168250.0 86900.0 0.52 982360.0 -64082.8125 -0.367033822921664 -0.4608 -0.4042 2071078 Maybridge1_003472 CCOC(=O)c1ccc(NC(=S)N2CCOCC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F19 compound treatment 1069550.0 -64500.0 -0.32 1161360.0 80000.0 0.48 1051840.0 5397.1875 0.0309123505019387 0.1104 0.1931 2071079 Maybridge1_003473 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4cccc(c4)[N+](=O)[O-])cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F20 compound treatment 1159200.0 25100.0 0.12 1061020.0 -20400.0 -0.12 935040.0 -111402.8125 -0.638058764291912 -0.3674 -0.556 2071080 Maybridge1_003474 Cc1onc(c1C(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F21 compound treatment 1250340.0 116000.0 0.57 1013870.0 -67500.0 -0.4 977120.0 -69322.8125 -0.397045883208648 -0.1331 -0.1662 1271674 Maybridge1_003475 Brc1ccc(cc1)S(=O)(=O)N(CCC#N)CC2CCCO2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F22 compound treatment 1224220.0 90100.0 0.44 1022790.0 -58600.0 -0.35 982310.0 -64132.8125 -0.367320197542723 -0.159 -0.2369 2071081 Maybridge1_003476 COc1cccc(NC(=S)N(CCC#N)C2CCCCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F23 mock treatment 1165230.0 31100.0 0.15 1092360.0 11000.0 0.07 1093790.0 47347.1875 0.271180657570449 0.2821 0.8879 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 F24 mock treatment 1127930.0 -6170.0 -0.03 955200.0 -126000.0 -0.75 1063300.0 16857.1875 0.0965494136486642 -0.3948 -0.5215 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G01 compound treatment 1173810.0 39700.0 0.19 1081720.0 346.0 0.0 1063840.0 17397.1875 0.0996422595561015 0.1707 0.7827 2071082 Maybridge1_003477 COc1ccc(/C=C/2\CC/C(=C\c3ccc(OC)cc3)/C2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G02 compound treatment 980410.0 -154000.0 -0.75 884490.0 -197000.0 -1.17 983890.0 -62552.8125 -0.358270759517258 -1.3163 -0.9165 2071083 Maybridge1_003478 Cc1nc(cs1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G03 compound treatment 32870.0 -1100000.0 -5.38 33340.0 -1050000.0 -6.23 35360.0 -1011082.8125 -5.79096914577934 -10.048 -0.9982 2071084 Maybridge1_003479 CN1C/C(=C\c2ccccc2)/C(=O)\C(=C\c3ccccc3)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G04 compound treatment 818900.0 -315000.0 -1.54 806660.0 -275000.0 -1.63 856570.0 -189872.8125 -1.08749509458193 -2.4601 -0.9862 2071085 Maybridge1_003480 Clc1ccc(Cc2nc(cs2)c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G05 compound treatment 1082780.0 -51300.0 -0.25 1111620.0 30200.0 0.18 980280.0 -66162.8125 -0.378947007157719 -0.2597 -0.5314 1494940 Maybridge1_003481 CNc1ccccc1C(=O)NCc2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G06 compound treatment 712520.0 -422000.0 -2.06 796250.0 -285000.0 -1.7 757930.0 -288512.8125 -1.65245494700714 -3.1221 -0.9949 2071086 Maybridge1_003482 S=C1NCCCN1C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G07 compound treatment 637280.0 -497000.0 -2.43 556050.0 -525000.0 -3.12 557510.0 -488932.8125 -2.80035897806009 -4.8218 -0.9948 2071087 Maybridge1_003483 Clc1ccccc1CSC2=NCCN2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G08 compound treatment 883610.0 -250000.0 -1.22 789980.0 -291000.0 -1.73 903680.0 -142762.8125 -0.817672926620125 -2.1791 -0.9585 1632209 Maybridge1_003484 CCC(CO)N1CNC(=S)NC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G09 compound treatment 700110.0 -434000.0 -2.12 660180.0 -421000.0 -2.5 699300.0 -347142.8125 -1.98825782766094 -3.8182 -0.9951 2071088 Maybridge1_003485 Clc1ccccc1CSc2nc3ccccc3[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G10 compound treatment 544320.0 -590000.0 -2.88 445250.0 -636000.0 -3.78 463680.0 -582762.8125 -3.33776959193943 -5.7747 -0.994 2071089 Maybridge1_003486 Cc1cc(C)c(CSc2ccccn2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G11 compound treatment 656660.0 -477000.0 -2.33 738770.0 -343000.0 -2.04 728640.0 -317802.8125 -1.82021320002351 -3.5739 -0.9949 2071090 Maybridge1_003487 Clc1ccc(cc1)C2=NNC(N2)c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G12 compound treatment 1242890.0 109000.0 0.53 881830.0 -200000.0 -1.19 1017060.0 -29382.8125 -0.16828983590671 -0.4754 -0.3626 2071091 Maybridge1_003488 CSC1=NCN(Cc2ccccc2)CN1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G13 compound treatment 674240.0 -460000.0 -2.25 830130.0 -251000.0 -1.49 718120.0 -328322.8125 -1.88046642029433 -3.2454 -0.9868 2071092 Maybridge1_003489 CNC(=S)NN=C1CCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G14 compound treatment 777960.0 -356000.0 -1.74 803720.0 -278000.0 -1.65 740320.0 -306122.8125 -1.75331608854413 -2.9701 -0.9996 2071093 Maybridge1_003490 CCCCCCCCCCCCN1CNC(=S)NC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G15 compound treatment 1040100.0 -94000.0 -0.46 1132570.0 51200.0 0.3 972770.0 -73672.8125 -0.421960475240782 -0.333 -0.4798 1017701 Maybridge1_003491 CSc1nc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G16 compound treatment 1170250.0 36200.0 0.18 1057650.0 -23700.0 -0.14 1001880.0 -44562.8125 -0.255233170860226 -0.1268 -0.372 1329134 Maybridge1_003492 Cc1nn(Cc2ccccc2Cl)c(=N)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G17 compound treatment 944670.0 -189000.0 -0.93 853410.0 -228000.0 -1.36 814200.0 -232242.8125 -1.33016894846733 -2.085 -0.9869 1250043 Maybridge1_003493 Clc1ccc(cc1)C2Nc3ccccc3-c4nc5ccccc5n24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G18 compound treatment 636760.0 -497000.0 -2.43 648000.0 -433000.0 -2.58 602120.0 -444322.8125 -2.54485554115124 -4.3601 -0.9997 1231206 Maybridge1_003494 COC(=O)c1ccccc1NC(=S)N(N)CCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G19 compound treatment 1060740.0 -73400.0 -0.36 1074400.0 -6970.0 -0.04 863330.0 -183112.8125 -1.04877724581475 -0.8364 -0.7541 2071094 Maybridge1_003495 N1C(Oc2ccccc12)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G20 compound treatment 1188890.0 54800.0 0.27 1158400.0 77000.0 0.46 1019490.0 -26952.8125 -0.154372029323242 0.3299 0.597 1245464 Maybridge1_003496 Clc1cccc(c1)C(=O)NCc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G21 compound treatment 1112160.0 -21900.0 -0.11 1131390.0 50000.0 0.3 1026510.0 -19932.8125 -0.114165032526557 0.0439 0.1307 2071095 Maybridge1_003497 CSC1=NCCN1S(=O)(=O)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G22 compound treatment 1010520.0 -124000.0 -0.6 924030.0 -157000.0 -0.94 791360.0 -255082.8125 -1.46098487536709 -1.7323 -0.943 1370776 Maybridge1_003498 Clc1ccccc1C(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G23 mock treatment 1090990.0 -43100.0 -0.21 1022370.0 -59000.0 -0.35 1077680.0 31237.1875 0.178910754665236 -0.2209 -0.4945 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 G24 mock treatment 1078340.0 -55800.0 -0.27 1132100.0 50700.0 0.3 1025220.0 -21222.8125 -0.121553497749879 -0.0533 -0.1256 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H01 compound treatment 319040.0 -815000.0 -3.98 335490.0 -746000.0 -4.44 292870.0 -753572.8125 -4.31608257240122 -7.3518 -0.999 2071096 Maybridge1_003499 Nc1ccccc1C(=O)N/N=C/c2cc(Br)ccc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H02 compound treatment 1226880.0 92800.0 0.45 979840.0 -102000.0 -0.6 1118460.0 72017.1875 0.412477895600966 0.1513 0.1758 2071097 Maybridge1_003500 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H03 compound treatment 997380.0 -137000.0 -0.67 963520.0 -118000.0 -0.7 982140.0 -64302.8125 -0.368293871254324 -1.0029 -0.9682 2071098 Maybridge1_003501 CC(=O)Nc1ccc(F)cc1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H04 compound treatment 1012590.0 -122000.0 -0.59 953840.0 -128000.0 -0.76 1052120.0 5677.1875 0.0325160483798691 -0.7618 -0.7906 2071099 Maybridge1_003502 COc1cc(/C=N/c2ccc(F)cc2)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H05 compound treatment 1002080.0 -132000.0 -0.65 943690.0 -138000.0 -0.82 976920.0 -69522.8125 -0.398191381692884 -1.075 -0.9635 2071100 Maybridge1_003503 COC(=O)c1cc(ccc1Sc2ccccc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H06 compound treatment 1043640.0 -90500.0 -0.44 1083740.0 2370.0 0.01 989440.0 -57002.8125 -0.326483176579708 -0.4355 -0.7924 2071101 Maybridge1_003504 [O-][N+](=O)c1ccccc1SCC(=O)NNC(=S)Nc2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H07 compound treatment 1160580.0 26500.0 0.13 1148190.0 66800.0 0.4 1134430.0 87987.1875 0.503945949567214 0.5951 0.909 2071102 Maybridge1_003505 FC(F)(F)c1cc(cc(c1)S(=O)(=O)c2ccccc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H08 compound treatment 942900.0 -191000.0 -0.93 1046800.0 -34600.0 -0.21 897070.0 -149372.8125 -0.855531651524126 -1.152 -0.8977 1464611 Maybridge1_003506 Oc1ccccc1c2nc3ccccc3c(=O)[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H09 compound treatment 28320.0 -1110000.0 -5.4 34920.0 -1050000.0 -6.22 25690.0 -1020752.8125 -5.84635399749216 -10.0873 -0.9983 1412023 Maybridge1_003507 O=C(CCN1CCOCC1)c2ccc3OCCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H10 compound treatment 728030.0 -406000.0 -1.98 635360.0 -446000.0 -2.65 567470.0 -478972.8125 -2.74331315354513 -4.2606 -0.9907 2071103 Maybridge1_003508 CC1(C)N/C(=N/c2cc(Cl)c(Cl)cc2Cl)/SC1=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H11 compound treatment 1015310.0 -119000.0 -0.58 965210.0 -116000.0 -0.69 922240.0 -124202.8125 -0.711370667283019 -1.1446 -0.9962 2071104 Maybridge1_003509 CC1(C)C2CCC1(C)/C(=N/Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])/C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H12 compound treatment 1182440.0 48300.0 0.24 1177860.0 96500.0 0.57 1100400.0 53957.1875 0.309039382474451 0.6461 0.932 2071105 Maybridge1_003510 Clc1ccccc1NC(=S)N(CCC#N)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H13 compound treatment 698190.0 -436000.0 -2.13 956750.0 -125000.0 -0.74 621800.0 -424642.8125 -2.43213849030241 -3.0617 -0.9231 1284432 Maybridge1_003511 COc1ccc(CC(=C(C#N)C#N)C)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H14 compound treatment 1230030.0 95900.0 0.47 1121610.0 40200.0 0.24 1173990.0 127547.1875 0.730525549749104 0.8305 0.9225 1510455 Maybridge1_003512 COc1ccccc1NC(=S)NCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H15 compound treatment 765180.0 -369000.0 -1.8 728840.0 -353000.0 -2.1 602240.0 -444202.8125 -2.54416824206069 -3.7199 -0.9901 2071106 Maybridge1_003513 Clc1ccc(cc1Cl)C2NN=C3C2N4CCC3CC4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H16 compound treatment 1172990.0 38900.0 0.19 1132570.0 51200.0 0.3 1096770.0 50327.1875 0.288248584985567 0.4519 0.9817 1737399 Maybridge1_003514 CCOC(=O)c1ccc(NC(=S)NCc2cccnc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H17 compound treatment 736230.0 -398000.0 -1.94 720090.0 -361000.0 -2.15 690830.0 -355612.8125 -2.03676968846834 -3.5386 -0.9992 2071107 Maybridge1_003515 Cc1cccc(C)c1/N=C\2/NC(C)(C)C(=C)S2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H18 compound treatment 1199300.0 65200.0 0.32 1101140.0 19800.0 0.12 1023800.0 -22642.8125 -0.129686536987955 0.1769 0.4867 2071108 Maybridge1_003516 S=C(Nc1cccc2ccccc12)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H19 compound treatment 790430.0 -344000.0 -1.68 829090.0 -252000.0 -1.5 806680.0 -239762.8125 -1.37323969147461 -2.6284 -0.9966 1646121 Maybridge1_003517 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)C(C)(C)C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H20 compound treatment 584520.0 -550000.0 -2.69 540210.0 -541000.0 -3.22 525010.0 -521432.8125 -2.98650248174844 -5.1325 -0.9973 1236412 Maybridge1_003518 Cc1onc(c1C(=O)Nc2ccc3OCOc3c2)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H21 compound treatment 377000.0 -757000.0 -3.7 366180.0 -715000.0 -4.25 365980.0 -680462.8125 -3.89734560148874 -6.8412 -0.9983 2071109 Maybridge1_003519 COc1cc(cc(OC)c1OC)C(=O)N/N=C/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H22 compound treatment 1013210.0 -121000.0 -0.59 879170.0 -202000.0 -1.2 810080.0 -236362.8125 -1.35376621724259 -1.8168 -0.9539 2071110 Maybridge1_003520 Clc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H23 mock treatment 1324090.0 190000.0 0.93 1128660.0 47300.0 0.28 1098250.0 51807.1875 0.296725273768913 0.8696 0.8573 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 H24 mock treatment 1228960.0 94900.0 0.46 1187050.0 106000.0 0.63 1158400.0 111957.1875 0.641233942902904 1.0006 0.9903 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I01 compound treatment 1104040.0 -30100.0 -0.15 1091040.0 9670.0 0.06 955310.0 -91132.8125 -0.521962492914589 -0.353 -0.6473 2071111 Maybridge1_003521 COc1ccc(/C=C/2\CC/C(=C\c3ccc(OC)c(OC)c3)/C2=O)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I02 compound treatment 908000.0 -226000.0 -1.1 745370.0 -336000.0 -2.0 807280.0 -239162.8125 -1.3698031960219 -2.5822 -0.9698 2071112 Maybridge1_003522 Clc1ccc(cc1)c2csc(n2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I03 compound treatment 1037340.0 -96800.0 -0.47 1024450.0 -56900.0 -0.34 1026670.0 -19772.8125 -0.113248633739168 -0.5338 -0.9011 1013283 Maybridge1_003523 CCOC(=O)CSc1nc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I04 compound treatment 1007770.0 -126000.0 -0.62 993200.0 -88200.0 -0.52 1015530.0 -30912.8125 -0.177052899311116 -0.7613 -0.9183 2071113 Maybridge1_003524 Cc1ccc(CC(=S)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I05 compound treatment 992330.0 -142000.0 -0.69 956370.0 -125000.0 -0.74 838490.0 -207952.8125 -1.19104815755686 -1.5167 -0.9688 1461883 Maybridge1_003525 CNc1ccc(Cl)cc1C(=O)NCc2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I06 compound treatment 998430.0 -136000.0 -0.66 1056670.0 -24700.0 -0.15 922790.0 -123652.8125 -0.70822054645137 -0.8764 -0.8933 2071114 Maybridge1_003526 CC(=O)Nc1ccc(cc1)/C(=N/O)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I07 compound treatment 1189920.0 55800.0 0.27 1162400.0 81000.0 0.48 1026340.0 -20102.8125 -0.115138706238157 0.3692 0.6528 1030955 Maybridge1_003527 COC(=O)c1ccccc1NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I08 compound treatment 270770.0 -863000.0 -4.22 292900.0 -788000.0 -4.69 256960.0 -789482.8125 -4.5217568252458 -7.753 -0.9991 2071115 Maybridge1_003528 Cc1cc(C)c(CSC2=NCCN2)c(C)c1CSC3=NCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I09 compound treatment 1004740.0 -129000.0 -0.63 1246940.0 166000.0 0.98 970620.0 -75822.8125 -0.43427458394632 -0.0472 -0.0378 2071116 Maybridge1_003529 Nc1ccccc1C(=O)NNC(=O)c2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I10 compound treatment 769440.0 -365000.0 -1.78 788160.0 -293000.0 -1.74 764720.0 -281722.8125 -1.61356527346733 -2.9669 -0.9991 2071117 Maybridge1_003530 Cc1cc(C)c(CSc2nccn2C)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I11 compound treatment 857160.0 -277000.0 -1.35 856050.0 -225000.0 -1.34 750040.0 -296402.8125 -1.69764486221026 -2.5349 -0.9937 2071118 Maybridge1_003531 Clc1ccc(cc1)C2=NNC(N2)c3ccc4OCOc4c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I12 compound treatment 1443450.0 309000.0 1.51 1109810.0 28400.0 0.17 1055200.0 8757.1875 0.0501567250371043 0.9992 0.6566 1397307 Maybridge1_003532 CC(C)c1nc2ccccc2n1C3CC(=O)N(C3=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I13 compound treatment 1006100.0 -128000.0 -0.63 1090590.0 9220.0 0.05 788970.0 -257472.8125 -1.47467358225371 -1.1808 -0.7368 2071119 Maybridge1_003533 CNC(=S)NN=C1CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I14 compound treatment 1075760.0 -58300.0 -0.29 1143200.0 61800.0 0.37 982280.0 -64162.8125 -0.367492022315358 -0.1645 -0.2774 2071120 Maybridge1_003534 CN(N)C(=S)Nc1cc(Cl)ccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I15 compound treatment 1031420.0 -103000.0 -0.5 1031240.0 -50100.0 -0.3 816380.0 -230062.8125 -1.31768301498916 -1.2225 -0.8483 1565188 Maybridge1_003535 CN(C)c1ccc(cc1)C2Nc3ccccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I16 compound treatment 985760.0 -148000.0 -0.72 1038830.0 -42500.0 -0.25 967610.0 -78832.8125 -0.451514336134072 -0.8252 -0.9266 1604536 Maybridge1_003536 CNc1ccccc1C(=O)NC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I17 compound treatment 902560.0 -232000.0 -1.13 853680.0 -228000.0 -1.35 799630.0 -246812.8125 -1.41361851304393 -2.251 -0.9957 1340303 Maybridge1_003537 COc1ccc(CNc2ccccc2c3nc4ccccc4[nH]3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I18 compound treatment 1287140.0 153000.0 0.75 1113920.0 32500.0 0.19 1165710.0 119267.1875 0.683101912501732 0.9378 0.9095 2071121 Maybridge1_003538 Clc1ccc(NC(=O)CC2NCCN(Cc3ccccc3)C2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I19 compound treatment 663310.0 -471000.0 -2.3 575230.0 -506000.0 -3.01 561630.0 -484812.8125 -2.77676170928482 -4.6689 -0.9941 2071122 Maybridge1_003539 CN1CNC(=NC1)SCc2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I20 compound treatment 1040610.0 -93500.0 -0.46 1035810.0 -45600.0 -0.27 956000.0 -90442.8125 -0.518010523143975 -0.7192 -0.9695 1470325 Maybridge1_003540 Clc1ccc(cc1)C(=C)NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I21 compound treatment 1069820.0 -64300.0 -0.31 1004090.0 -77300.0 -0.46 955600.0 -90842.8125 -0.520301520112447 -0.747 -0.9805 2071123 Maybridge1_003541 CSC1=NCCN1S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I22 compound treatment 1172210.0 38100.0 0.19 1236800.0 155000.0 0.92 966930.0 -79512.8125 -0.455409030980475 0.3782 0.3612 2071124 Maybridge1_003542 OC(=O)CCc1nc(no1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I23 mock treatment 1104510.0 -29600.0 -0.14 1320050.0 239000.0 1.42 1030430.0 -16012.8125 -0.0917132622355301 0.683 0.4778 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 I24 mock treatment 1184930.0 50800.0 0.25 1072980.0 -8390.0 -0.05 1070740.0 24297.1875 0.139161957262245 0.1949 0.6744 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J01 compound treatment 903490.0 -231000.0 -1.13 818290.0 -263000.0 -1.56 824860.0 -221582.8125 -1.26911387925755 -2.2865 -0.9906 2071125 Maybridge1_003543 NC(=O)N/N=C/1\CCOc2ccc3ccccc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J02 compound treatment 990510.0 -144000.0 -0.7 911200.0 -170000.0 -1.01 923210.0 -123232.8125 -0.705814999634475 -1.3968 -0.9841 2071126 Maybridge1_003544 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J03 compound treatment 1300390.0 166000.0 0.81 1118650.0 37300.0 0.22 1019900.0 -26542.8125 -0.152023757430558 0.5093 0.5951 1049119 Maybridge1_003545 CC(C)c1ccc(NC(=O)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J04 compound treatment 1050150.0 -83900.0 -0.41 996680.0 -84700.0 -0.5 1165060.0 118617.1875 0.679379042427965 -0.1353 -0.144 2071127 Maybridge1_003546 Nc1ccccc1Sc2ccccc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J05 compound treatment 952560.0 -182000.0 -0.89 905730.0 -176000.0 -1.04 944160.0 -102282.8125 -0.585824033410749 -1.4533 -0.9752 2071128 Maybridge1_003547 COC(=O)c1cc(ccc1Sc2ccc(Cl)cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J06 compound treatment 1086240.0 -47900.0 -0.23 1101730.0 20400.0 0.12 1087050.0 40607.1875 0.232577358651695 0.0692 0.1969 2071129 Maybridge1_003548 [O-][N+](=O)c1ccccc1SCc2nnc(S)n2c3cccc(c3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J07 compound treatment 1030660.0 -103000.0 -0.51 926890.0 -154000.0 -0.92 891770.0 -154672.8125 -0.885887361356381 -1.3336 -0.9716 1303668 Maybridge1_003549 CCOC(=O)c1sc2ccc(NC(=O)c3ccccc3Cl)cc2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J08 compound treatment 686400.0 -448000.0 -2.19 541080.0 -540000.0 -3.21 661240.0 -385202.8125 -2.20624618921106 -4.3916 -0.9826 2071130 Maybridge1_003550 CCOC(=O)c1ccc(/N=C\2/NC(CC)(CC)C(=C)S2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J09 compound treatment 30930.0 -1100000.0 -5.39 30620.0 -1050000.0 -6.25 25030.0 -1021412.8125 -5.85013414249014 -10.0969 -0.9982 1057159 Maybridge1_003551 Cc1ccc(C(=O)CCN2CCOCC2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J10 compound treatment 948480.0 -186000.0 -0.91 891680.0 -190000.0 -1.13 746210.0 -300232.8125 -1.71958115818338 -2.1677 -0.9644 1378916 Maybridge1_003552 COc1cc(Cl)cc(OC)c1NC(=S)N2CCN3C(=O)c4ccccc4C23c5ccccc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J11 compound treatment 1247720.0 114000.0 0.56 1159330.0 78000.0 0.46 956520.0 -89922.8125 -0.515032227084961 0.2908 0.3275 1652494 Maybridge1_003553 Cc1onc(c1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J12 compound treatment 1181320.0 47200.0 0.23 935220.0 -146000.0 -0.87 954880.0 -91562.8125 -0.524425314655697 -0.6713 -0.6449 1192076 Maybridge1_003554 CC(C)c1ccc(NC(=S)Nc2c(C)cccc2C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J13 compound treatment 1427360.0 293000.0 1.43 1292480.0 211000.0 1.26 1219630.0 173187.1875 0.99192830385177 2.1247 0.9893 2071131 Maybridge1_003555 COc1ccc(cc1)C(CCC#N)(CCC#N)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J14 compound treatment 1270610.0 137000.0 0.67 1278450.0 197000.0 1.17 978900.0 -67542.8125 -0.386850946698947 0.8383 0.5976 1213155 Maybridge1_003556 COc1cccc(NC(=S)NCc2ccncc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J15 compound treatment 1225280.0 91200.0 0.45 1166500.0 85100.0 0.51 953380.0 -93062.8125 -0.533016553287467 0.2417 0.2812 2071132 Maybridge1_003557 C1Oc2ccc(cc2O1)C3NN=C4C3N5CCC4CC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J16 compound treatment 747600.0 -386000.0 -1.89 674590.0 -407000.0 -2.42 556850.0 -489592.8125 -2.80413912305806 -4.1058 -0.9877 2071133 Maybridge1_003558 Clc1ccc(NC(=S)NCc2cccnc2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J17 compound treatment 1224240.0 90100.0 0.44 1236120.0 155000.0 0.92 966910.0 -79532.8125 -0.455523580828898 0.5226 0.4677 1081790 Maybridge1_003559 FC(F)(F)c1cccc(NC(=O)COc2cc(Cl)c(Cl)cc2Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J18 compound treatment 1019930.0 -114000.0 -0.56 900000.0 -181000.0 -1.08 751120.0 -295322.8125 -1.69145917039538 -1.9213 -0.9227 1736870 Maybridge1_003560 Cc1onc(c1C(=O)N2CCOCC2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J19 compound treatment 963150.0 -171000.0 -0.84 707440.0 -374000.0 -2.22 759370.0 -287072.8125 -1.64420735792064 -2.7153 -0.9399 1568250 Maybridge1_003561 Clc1ccc(Cl)c(c1)S(=O)(=O)NC2(CCCCC2)C#C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J20 compound treatment 1141830.0 7730.0 0.04 1069920.0 -11500.0 -0.07 876000.0 -170442.8125 -0.976209916838393 -0.5811 -0.5934 1226028 Maybridge1_003562 Cc1onc(c1C(=O)Nc2ccc(C)c(F)c2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J21 compound treatment 815230.0 -319000.0 -1.56 784430.0 -297000.0 -1.77 751550.0 -294892.8125 -1.68899634865427 -2.8941 -0.9987 2071134 Maybridge1_003563 ClC(Cl)C(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J22 compound treatment 1077850.0 -56200.0 -0.27 1032220.0 -49200.0 -0.29 923620.0 -122822.8125 -0.703466727741791 -0.7336 -0.9058 2071135 Maybridge1_003564 Cc1ccc(Cl)cc1NC(=S)N(CCC#N)/N=C/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J23 mock treatment 1416670.0 283000.0 1.38 1094050.0 12700.0 0.08 1027560.0 -18882.8125 -0.108151165484317 0.7782 0.5611 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 J24 mock treatment 1215790.0 81700.0 0.4 1165440.0 84100.0 0.5 1077490.0 31047.1875 0.177822531105212 0.6217 0.9364 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K01 compound treatment 1147130.0 13000.0 0.06 1009880.0 -71500.0 -0.43 1097730.0 51287.1875 0.2937469777099 -0.0391 -0.0751 1913140 Maybridge1_003565 O=C/1/C(=C/c2ccc3OCOc3c2)/CC\C1=C/c4ccc5OCOc5c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K02 compound treatment 838590.0 -296000.0 -1.44 828490.0 -253000.0 -1.5 978680.0 -67762.8125 -0.388110995031607 -1.9259 -0.9082 2071136 Maybridge1_003566 Nc1nc(cs1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K03 compound treatment 1007460.0 -127000.0 -0.62 973300.0 -108000.0 -0.64 966720.0 -79722.8125 -0.456611804388923 -0.9919 -0.9897 1344801 Maybridge1_003567 CNc1ccccc1C(=O)NC2CC(C)CC(C)(C)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K04 compound treatment 1158150.0 24100.0 0.12 1053610.0 -27800.0 -0.17 1043400.0 -3042.8125 -0.0174276855328225 -0.0375 -0.1845 2071137 Maybridge1_003568 Clc1ccc(Cc2nc(cs2)c3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K05 compound treatment 1015120.0 -119000.0 -0.58 1123570.0 42200.0 0.25 980830.0 -65612.8125 -0.37579688632607 -0.4077 -0.5537 2071138 Maybridge1_003569 CN1C/C(=C\c2ccco2)/C(=O)\C(=C\c3ccco3)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K06 compound treatment 1342820.0 209000.0 1.02 1109490.0 28100.0 0.17 1335700.0 289257.1875 1.65671834917816 1.6418 0.8408 1712799 Maybridge1_003570 OCCCN1CNC(=S)NC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K07 compound treatment 1204450.0 70400.0 0.34 1067140.0 -14200.0 -0.08 1165380.0 118937.1875 0.681211840002742 0.5429 0.7072 2071139 Maybridge1_003571 Clc1ccc(CSC2=NCCCN2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K08 compound treatment 1075520.0 -58600.0 -0.29 1022360.0 -59000.0 -0.35 914650.0 -131792.8125 -0.754842334759777 -0.8037 -0.913 2071140 Maybridge1_003572 Cc1cc(C)c(CSC(=N)N)c(C)c1CSC(=N)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K09 compound treatment 654080.0 -480000.0 -2.35 739770.0 -342000.0 -2.03 606640.0 -439802.8125 -2.5189672754075 -3.9812 -0.9962 1035818 Maybridge1_003573 Clc1ccc(CSc2nc3ccccc3[nH]2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K10 compound treatment 1047780.0 -86300.0 -0.42 1111160.0 29800.0 0.18 1004450.0 -41992.8125 -0.240513515337793 -0.2801 -0.542 2071141 Maybridge1_003574 CC(C)(C)N1CNC(=S)NC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K11 compound treatment 899410.0 -235000.0 -1.15 853370.0 -228000.0 -1.36 830680.0 -215762.8125 -1.23577987336628 -2.1583 -0.9976 2071142 Maybridge1_003575 CNC(=S)N/N=C(\C)/c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K12 compound treatment 710570.0 -424000.0 -2.07 757290.0 -324000.0 -1.93 814880.0 -231562.8125 -1.32627425362093 -3.0731 -0.9839 1074367 Maybridge1_003576 CCOC(=O)c1c(NC(=O)C)sc2CCCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K13 compound treatment 758330.0 -376000.0 -1.84 777860.0 -304000.0 -1.8 710180.0 -336262.8125 -1.9259427101185 -3.214 -0.9996 2071143 Maybridge1_003577 CNC(=S)NN=C1CCCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K14 compound treatment 1184380.0 50300.0 0.25 1296590.0 215000.0 1.28 904480.0 -141962.8125 -0.81309093268318 0.4113 0.2678 2071144 Maybridge1_003578 COC(=O)c1ccccc1NC(=S)N(C)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K15 compound treatment 963760.0 -170000.0 -0.83 904740.0 -177000.0 -1.05 686000.0 -360442.8125 -2.06443347686264 -2.2788 -0.9259 1181884 Maybridge1_003579 CN(C)c1ccc(cc1)C2Nc3cc(Cl)ccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K16 compound treatment 1006400.0 -128000.0 -0.62 1012250.0 -69100.0 -0.41 889920.0 -156522.8125 -0.896483222335565 -1.1151 -0.9555 1597144 Maybridge1_003580 CNc1ccc(Cl)cc1C(=O)NC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K17 compound treatment 897920.0 -236000.0 -1.15 731950.0 -349000.0 -2.08 650500.0 -395942.8125 -2.26775945781454 -3.1752 -0.9665 1090814 Maybridge1_003581 Nc1ccc(Cl)cc1c2nc3ccccc3[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K18 compound treatment 1414880.0 281000.0 1.37 1151260.0 69900.0 0.42 1151600.0 105157.1875 0.602286994438879 1.3797 0.8874 2071145 Maybridge1_003582 NNC(=O)CC1NCCN(Cc2ccccc2)C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K19 compound treatment 587910.0 -546000.0 -2.67 796160.0 -285000.0 -1.7 613600.0 -432842.8125 -2.47910392815609 -3.9512 -0.9834 2071146 Maybridge1_003583 CN1CNC(=NC1)SCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K20 compound treatment 1029870.0 -104000.0 -0.51 785280.0 -296000.0 -1.76 886360.0 -160082.8125 -0.916873095354966 -1.8399 -0.8978 1226276 Maybridge1_003584 c1nc(c2ccccc2)n3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K21 compound treatment 630990.0 -503000.0 -2.46 615630.0 -466000.0 -2.77 539810.0 -506632.8125 -2.90173559391498 -4.6935 -0.9977 2071147 Maybridge1_003585 COCCCN1CNC(=NC1)SCc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K22 compound treatment 1073600.0 -60500.0 -0.3 1202360.0 121000.0 0.72 907630.0 -138812.8125 -0.795049331556463 -0.2143 -0.1927 1650617 Maybridge1_003586 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K23 mock treatment 1177240.0 43100.0 0.21 1131140.0 49800.0 0.3 933390.0 -113052.8125 -0.64750912678686 -0.0813 -0.1095 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 K24 mock treatment 1265920.0 132000.0 0.64 1096170.0 14800.0 0.09 1113060.0 66617.1875 0.381549436526593 0.6429 0.853 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L01 compound treatment 1120980.0 -13100.0 -0.06 1094970.0 13600.0 0.08 947210.0 -99232.8125 -0.568355181526149 -0.3185 -0.5513 2071148 Maybridge1_003587 COc1ccc(CCNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L02 compound treatment 1010310.0 -124000.0 -0.6 883100.0 -198000.0 -1.18 787090.0 -259352.8125 -1.48544126800553 -1.8875 -0.9482 2071149 Maybridge1_003588 Fc1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L03 compound treatment 988210.0 -146000.0 -0.71 978090.0 -103000.0 -0.61 899220.0 -147222.8125 -0.843217542818588 -1.253 -0.9917 2071150 Maybridge1_003589 [O-][N+](=O)c1cc(F)ccc1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L04 compound treatment 878080.0 -256000.0 -1.25 851400.0 -230000.0 -1.37 867590.0 -178852.8125 -1.02437812810052 -2.1032 -0.9932 2071151 Maybridge1_003590 Nc1ccccc1Sc2ccc(Cl)cc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L05 compound treatment 1298610.0 165000.0 0.8 1151110.0 69700.0 0.41 1058250.0 11807.1875 0.067625576921704 0.7425 0.8187 2071152 Maybridge1_003591 CC(=O)c1cc2cc(Cl)ccc2o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L06 compound treatment 670680.0 -463000.0 -2.26 661860.0 -420000.0 -2.49 587100.0 -459342.8125 -2.63088247731736 -4.2665 -0.9981 2071153 Maybridge1_003592 [O-][N+](=O)c1ccccc1SCC(=O)NNC(=S)NC2CC3CC2C=C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L07 compound treatment 1449330.0 315000.0 1.54 1280710.0 199000.0 1.19 1076920.0 30477.1875 0.174557860425139 1.6744 0.8581 2071154 Maybridge1_003593 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L08 compound treatment 1308660.0 175000.0 0.85 1279360.0 198000.0 1.18 1198900.0 152457.1875 0.873197385960704 1.6763 0.9884 1150396 Maybridge1_003594 O=C1N2CCNC2(c3ccccc13)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L09 compound treatment 35920.0 -1100000.0 -5.37 65710.0 -1020000.0 -6.04 29030.0 -1017412.8125 -5.82722417280541 -9.9491 -0.9988 1562697 Maybridge1_003595 CCc1cc2c(cc1C(=O)CCN3CCCC3)C(C)(C)CCC2(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L10 compound treatment 1208160.0 74100.0 0.36 1147770.0 66400.0 0.39 938350.0 -108092.8125 -0.619100764377806 0.0794 0.097 1382047 Maybridge1_003596 CSc1cccc(NC(=S)N2CCN3C(=O)c4ccccc4C23c5ccccc5)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L11 compound treatment 1059130.0 -75000.0 -0.37 918280.0 -163000.0 -0.97 950200.0 -96242.8125 -0.55122997918682 -1.0897 -0.928 1599520 Maybridge1_003597 CC(NC1(C#N)C2CC3CC(C2)CC1C3)c4ccc(C)cc4C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L12 compound treatment 715480.0 -419000.0 -2.05 1003890.0 -77500.0 -0.46 740830.0 -305612.8125 -1.75039506740933 -2.4575 -0.8998 2071155 Maybridge1_003598 CC(C)c1ccc(NC(=S)Nc2ccccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L13 compound treatment 1399530.0 265000.0 1.3 1348860.0 267000.0 1.59 1236660.0 190217.1875 1.08946749978447 2.2961 0.9882 1678992 Maybridge1_003599 Cc1onc(c1C(=O)N2CCCN3C2c4ccccc4C3=O)c5ccccc5Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L14 compound treatment 1224590.0 90500.0 0.44 1077180.0 -4190.0 -0.02 964280.0 -82162.8125 -0.470586885896602 -0.0308 -0.0477 1253884 Maybridge1_003600 CCOC(=O)c1ccc(NC(=S)NCc2ccncc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L15 compound treatment 1350260.0 216000.0 1.06 1164210.0 82800.0 0.49 1064990.0 18547.1875 0.106228875840459 0.9555 0.8165 1387935 Maybridge1_003601 O=C1N2CCCN(C2c3ccccc13)S(=O)(=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L16 compound treatment 1318140.0 184000.0 0.9 1192860.0 111000.0 0.66 898590.0 -147852.8125 -0.846825863043932 0.413 0.2946 2071156 Maybridge1_003602 FC(F)(F)c1cccc(NC(=S)N2CCOCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L17 compound treatment 919410.0 -215000.0 -1.05 812040.0 -269000.0 -1.6 631890.0 -414552.8125 -2.3743480917727 -2.9011 -0.9512 2071157 Maybridge1_003603 [O-][N+](=O)c1cccc(/C=C/c2ccccn2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L18 compound treatment 1395900.0 262000.0 1.28 1424800.0 343000.0 2.04 970260.0 -76182.8125 -0.436336481217945 1.6657 0.6802 1370915 Maybridge1_003604 Cc1onc(c1C(=O)N2CCCCC2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L19 compound treatment 1237530.0 103000.0 0.51 1169760.0 88400.0 0.53 984280.0 -62162.8125 -0.356037037472998 0.3897 0.4802 1629964 Maybridge1_003605 Cc1ccc(cc1)S(=O)(=O)Nc2cccc(CCc3ccccn3)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L20 compound treatment 1189710.0 55600.0 0.27 1172260.0 90900.0 0.54 870350.0 -176092.8125 -1.00857024901806 -0.1134 -0.0964 2071158 Maybridge1_003606 CSc1cccc(NC(=O)c2c(C)onc2c3ccccc3Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L21 compound treatment 1353780.0 220000.0 1.07 1137060.0 55700.0 0.33 990480.0 -55962.8125 -0.32052658446168 0.6258 0.5358 1731713 Maybridge1_003607 Clc1ccc(cc1)C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L22 compound treatment 1230340.0 96200.0 0.47 1132400.0 51000.0 0.3 1002590.0 -43852.8125 -0.251166651241188 0.3017 0.4918 2071159 Maybridge1_003608 Cc1ccc(NC(=S)NCc2cccnc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L23 mock treatment 1098850.0 -35200.0 -0.17 1164190.0 82800.0 0.49 1028540.0 -17902.8125 -0.102538222911561 0.1257 0.2364 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 L24 mock treatment 1448230.0 314000.0 1.53 1015880.0 -65500.0 -0.39 1085160.0 38717.1875 0.221752397975664 0.7893 0.4936 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M01 compound treatment 1165050.0 31000.0 0.15 1090970.0 9600.0 0.06 999640.0 -46802.8125 -0.268062753883669 -0.0345 -0.1102 2071160 Maybridge1_003609 Clc1ccc(/C=C/2\CC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M02 compound treatment 1018880.0 -115000.0 -0.56 817600.0 -264000.0 -1.57 913290.0 -133152.8125 -0.762631724452583 -1.6709 -0.9117 1024036 Maybridge1_003610 Clc1ccc(cc1)C2=CSC3=NCCN23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M03 compound treatment 1101880.0 -32200.0 -0.16 1334750.0 253000.0 1.51 1155520.0 109077.1875 0.624738764729905 1.1397 0.6955 2071161 Maybridge1_003611 CC(C)c1nc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M04 compound treatment 916770.0 -217000.0 -1.06 861500.0 -220000.0 -1.31 905960.0 -140482.8125 -0.804614243899834 -1.8325 -0.9817 2071162 Maybridge1_003612 Clc1ccc(cc1)c2csc(Cc3ccccc3Cl)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M05 compound treatment 1169180.0 35100.0 0.17 1361870.0 280000.0 1.67 1090940.0 44497.1875 0.254857304170086 1.2091 0.7129 1013280 Maybridge1_003613 OC(=O)CSc1nc2ccccc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M06 compound treatment 823260.0 -311000.0 -1.52 752080.0 -329000.0 -1.96 683520.0 -362922.8125 -2.07863765806716 -3.2075 -0.9917 2071163 Maybridge1_003614 Clc1ccccc1CSC2=NCCCN2C3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M07 compound treatment 1323040.0 189000.0 0.92 1167260.0 85900.0 0.51 984070.0 -62372.8125 -0.357239810881446 0.6216 0.5581 2071164 Maybridge1_003615 Clc1ccccc1CSC2=NCCCN2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M08 compound treatment 1272030.0 138000.0 0.67 1043520.0 -37900.0 -0.23 1000490.0 -45952.8125 -0.263194385325666 0.1072 0.1414 1218071 Maybridge1_003616 NNC(=O)c1nc2ccccc2c(=O)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M09 compound treatment 253680.0 -880000.0 -4.3 79460.0 -1000000.0 -5.96 200000.0 -846442.8125 -4.84799479355623 -8.7223 -0.9908 1328191 Maybridge1_003617 Clc1ccc(cc1)c2csc(=N)n2c3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M10 compound treatment 1361380.0 227000.0 1.11 1486050.0 405000.0 2.41 975540.0 -70902.8125 -0.406095321234113 1.796 0.6699 2071165 Maybridge1_003618 Clc1ccc(cc1)C2=NC(N=C(S2)c3ccc(Cl)cc3)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M11 compound treatment 795040.0 -339000.0 -1.66 970690.0 -111000.0 -0.66 687460.0 -358982.8125 -2.05607133792771 -2.5235 -0.9274 2071166 Maybridge1_003619 CNC(=S)N/N=C(\C)/c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M12 compound treatment 1237040.0 103000.0 0.5 997180.0 -84200.0 -0.5 1071330.0 24887.1875 0.142541177790741 0.0836 0.1155 1493034 Maybridge1_003620 COC(=O)c1ccccc1NC(=S)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M13 compound treatment 1085450.0 -48600.0 -0.24 1331650.0 250000.0 1.49 1010310.0 -36132.8125 -0.206950409749676 0.6026 0.3961 2071167 Maybridge1_003621 CC1CN(CC(C)O1)C(=N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M14 compound treatment 1281360.0 147000.0 0.72 1300720.0 219000.0 1.3 1085570.0 39127.1875 0.224100669868348 1.2979 0.8616 1677509 Maybridge1_003622 Cc1c(Cl)cccc1NC(=S)N(N)CCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M15 compound treatment 1296480.0 162000.0 0.79 1040530.0 -40800.0 -0.24 899130.0 -147312.8125 -0.843733017136495 -0.1693 -0.1431 1272679 Maybridge1_003623 OC(=O)CCCc1nc(no1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M16 compound treatment 1414200.0 280000.0 1.37 1371230.0 290000.0 1.72 1126750.0 80307.1875 0.45995880777255 2.0508 0.9121 2071168 Maybridge1_003624 FC(F)(F)c1nn2cc(nc2s1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M17 compound treatment 849410.0 -285000.0 -1.39 861890.0 -219000.0 -1.31 862330.0 -184112.8125 -1.05450473823593 -2.1654 -0.9935 2071169 Maybridge1_003625 Clc1ccccc1C2Nc3ccccc3O2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M18 compound treatment 1272640.0 139000.0 0.68 1167600.0 86200.0 0.51 995290.0 -51152.8125 -0.292977345915803 0.5177 0.5763 1730982 Maybridge1_003626 Nc1ccc(Cl)cc1C(=O)NCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M19 compound treatment 459550.0 -675000.0 -3.3 492260.0 -589000.0 -3.5 459520.0 -586922.8125 -3.36159596041154 -5.8662 -0.9997 2071170 Maybridge1_003627 CCN1CNC(=NC1)SCc2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M20 compound treatment 808520.0 -326000.0 -1.59 925600.0 -156000.0 -0.93 699210.0 -347232.8125 -1.98877330197885 -2.6014 -0.96 2071171 Maybridge1_003628 [O-][N+](=O)c1ccccc1c2ncc3ccccn23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M21 compound treatment 396550.0 -738000.0 -3.6 407040.0 -674000.0 -4.01 364670.0 -681772.8125 -3.90484861656048 -6.6501 -0.999 2071172 Maybridge1_003629 CCN1CNC(=NC1)SCc2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M22 compound treatment 974680.0 -159000.0 -0.78 828880.0 -252000.0 -1.5 725700.0 -320742.8125 -1.83705202774178 -2.3772 -0.952 2071173 Maybridge1_003630 CNc1ccc(Cl)cc1C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M23 mock treatment 1040510.0 -93600.0 -0.46 1072220.0 -9150.0 -0.05 1046720.0 277.1875 0.0015875893054959 -0.2945 -0.6396 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 M24 mock treatment 1230910.0 96800.0 0.47 1053860.0 -27500.0 -0.16 1096010.0 49567.1875 0.28389569074547 0.3425 0.5953 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N01 compound treatment 1194440.0 60300.0 0.29 1153070.0 71700.0 0.43 990570.0 -55872.8125 -0.320011110143774 0.2316 0.3802 2071174 Maybridge1_003631 Cc1cccc2CCCN(C(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N02 compound treatment 1388400.0 254000.0 1.24 1218320.0 137000.0 0.81 1076320.0 29877.1875 0.171121364972431 1.2863 0.8602 2071175 Maybridge1_003632 COc1cc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c(OC)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N03 compound treatment 1292380.0 158000.0 0.77 1276060.0 195000.0 1.16 1065660.0 19217.1875 0.110066295762649 1.1784 0.8438 2071176 Maybridge1_003633 Nc1ccccc1C(=O)NCCCNC(=O)c2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N04 compound treatment 988720.0 -145000.0 -0.71 1138880.0 57500.0 0.34 883360.0 -163082.8125 -0.934055572618507 -0.7519 -0.6152 2071177 Maybridge1_003634 COc1cc(cc(OC)c1OC)C(=O)Nc2ccccc2Sc3ccc(Cl)cc3[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N05 compound treatment 997630.0 -136000.0 -0.67 954880.0 -126000.0 -0.75 970500.0 -75942.8125 -0.434961883036861 -1.0704 -0.9773 1180989 Maybridge1_003635 Clc1ccc2oc(cc2c1)C(=O)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N06 compound treatment 1175380.0 41300.0 0.2 1038560.0 -42800.0 -0.25 1017990.0 -28452.8125 -0.162963267955012 -0.1246 -0.3429 2071178 Maybridge1_003636 NS(=O)(=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N07 compound treatment 1191920.0 57800.0 0.28 1092100.0 10700.0 0.06 959170.0 -87272.8125 -0.499854372168833 -0.0887 -0.1535 2071179 Maybridge1_003637 N#CCCN/N=C/c1ccc2OCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N08 compound treatment 1251040.0 117000.0 0.57 1271650.0 190000.0 1.13 1122590.0 76147.1875 0.43613243930044 1.2349 0.9213 2071180 Maybridge1_003638 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCN3C(=O)c4ccccc4C23c5ccccc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N09 compound treatment 130610.0 -1000000.0 -4.9 173370.0 -908000.0 -5.4 122640.0 -923802.8125 -5.29107360725873 -9.0029 -0.9992 1699549 Maybridge1_003639 O=C(CCN1CCCC1)c2ccc3ccccc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N10 compound treatment 1203200.0 69100.0 0.34 1234720.0 153000.0 0.91 1107120.0 60677.1875 0.347528131544782 0.9221 0.8929 1490310 Maybridge1_003640 CCOC(=O)c1ccc(NC(=S)N2CCN3C(=O)c4ccccc4C23c5ccccc5)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N11 compound treatment 1162610.0 28500.0 0.14 1100760.0 19400.0 0.12 1002450.0 -43992.8125 -0.251968500180153 0.0015 0.0049 1596245 Maybridge1_003641 Cc1onc(c1C(=O)N(CCC#N)Cc2ccccc2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N12 compound treatment 1250240.0 116000.0 0.57 1273920.0 193000.0 1.14 1108990.0 62547.1875 0.358238542372389 1.1955 0.9008 2071181 Maybridge1_003642 Clc1ccccc1NC(=S)NCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N13 compound treatment 1416730.0 283000.0 1.38 1401720.0 320000.0 1.9 1289080.0 242637.1875 1.38970265250274 2.6994 0.9879 1193847 Maybridge1_003643 Cc1onc(c1C(=O)NC(C)(C)CCO)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N14 compound treatment 1241300.0 107000.0 0.52 1231780.0 150000.0 0.89 899520.0 -146922.8125 -0.841499295092234 0.3329 0.2494 1545358 Maybridge1_003644 Cc1cccc(NC(=S)NCc2cccnc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N15 compound treatment 977340.0 -157000.0 -0.77 801530.0 -280000.0 -1.66 781530.0 -264912.8125 -1.51728612586729 -2.279 -0.9581 2071182 Maybridge1_003645 FC(F)(F)c1cccc(/N=C/2\NC3(CCCCC3)C(=C)S2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N16 compound treatment 1307620.0 174000.0 0.85 1185050.0 104000.0 0.62 972970.0 -73472.8125 -0.420814976756546 0.6025 0.5334 2071183 Maybridge1_003646 COc1cccc(NC(=S)N2CCOCC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N17 compound treatment 1320880.0 187000.0 0.91 1357040.0 276000.0 1.64 950250.0 -96192.8125 -0.550943604565761 1.1552 0.5908 2071184 Maybridge1_003647 CC(C)c1ccc(/C=N/c2ccc(cc2)C(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N18 compound treatment 1250120.0 116000.0 0.57 1155360.0 74000.0 0.44 1046480.0 37.1875 2.1299112441264E-4 0.5814 0.8103 2071185 Maybridge1_003648 CC1CN(CC(C)O1)C(=S)Nc2ccccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N19 compound treatment 1307710.0 174000.0 0.85 1264320.0 183000.0 1.09 1002880.0 -43562.8125 -0.249505678439046 0.9738 0.6946 1215090 Maybridge1_003649 Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2cccc(CCc3ccccn3)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N20 compound treatment 1207750.0 73700.0 0.36 1264420.0 183000.0 1.09 988080.0 -58362.8125 -0.334272566272513 0.6432 0.5386 2071186 Maybridge1_003650 CCCCNC(=S)N(CCC#N)C1CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N21 compound treatment 1225630.0 91500.0 0.45 1087040.0 5670.0 0.03 1050400.0 3957.1875 0.0226647614154392 0.2907 0.6474 1734074 Maybridge1_003651 Cc1onc(c1C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N22 compound treatment 1267520.0 133000.0 0.65 1218470.0 137000.0 0.82 861730.0 -184712.8125 -1.05794123368864 0.2362 0.159 2071187 Maybridge1_003652 Cc1c(Cl)cccc1NC(=S)NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N23 mock treatment 1369790.0 236000.0 1.15 1332180.0 251000.0 1.49 1142460.0 96017.1875 0.549937713709291 1.8434 0.9392 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 N24 mock treatment 1175580.0 41500.0 0.2 1075760.0 -5610.0 -0.03 883370.0 -163072.8125 -0.933998297694295 -0.4415 -0.4617 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O01 compound treatment 523130.0 -611000.0 -2.99 585540.0 -496000.0 -2.95 510480.0 -535962.8125 -3.06972294662819 -5.1981 -0.9999 2071188 Maybridge1_003653 O=C/1/C(=C/c2cccc3ccccc23)/CC\C1=C/c4cccc5ccccc45 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O02 compound treatment 1001920.0 -132000.0 -0.65 1072530.0 -8840.0 -0.05 987280.0 -59162.8125 -0.338854560209457 -0.5988 -0.819 2071189 Maybridge1_003654 Clc1ccc(cc1)C2=CSC3=NCCCN23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O03 compound treatment 1195720.0 61600.0 0.3 1162080.0 80700.0 0.48 1168070.0 121627.1875 0.696618794615717 0.8531 0.9501 1508216 Maybridge1_003655 CNc1ccccc1C(=O)NCCc2ccc(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O04 compound treatment 1144820.0 10700.0 0.05 1200260.0 119000.0 0.71 996060.0 -50382.8125 -0.288567176751495 0.2718 0.3551 2071190 Maybridge1_003656 COc1ccc(Cc2nc(cs2)c3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O05 compound treatment 35140.0 -1100000.0 -5.37 32670.0 -1050000.0 -6.24 27320.0 -1019122.8125 -5.83701818484563 -10.0704 -0.9981 2071191 Maybridge1_003657 CN1C/C(=C\c2ccccc2Cl)/C(=O)\C(=C\c3ccccc3Cl)\C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O06 compound treatment 496850.0 -637000.0 -3.11 435960.0 -645000.0 -3.84 392840.0 -653602.8125 -3.74350515505583 -6.1747 -0.996 2071192 Maybridge1_003658 Clc1ccc(CSC2=NCCCN2C3CCCCC3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O07 compound treatment 1287130.0 153000.0 0.75 1139220.0 57800.0 0.34 1095200.0 48757.1875 0.279256421884314 0.7915 0.9107 2071193 Maybridge1_003659 Cc1ccc(CSC2=NCCCN2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O08 compound treatment 1270810.0 137000.0 0.67 1285160.0 204000.0 1.21 967930.0 -78512.8125 -0.449681538559295 0.8257 0.5675 1482022 Maybridge1_003660 CCOC(=O)c1nc2sc3CCCCc3c2c(=O)[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O09 compound treatment 1005720.0 -128000.0 -0.63 984560.0 -96800.0 -0.58 842790.0 -203652.8125 -1.16641994014579 -1.3679 -0.9473 1226826 Maybridge1_003661 Nc1ccccc1c2nc3ccccc3[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O10 compound treatment 1403480.0 269000.0 1.32 1251570.0 170000.0 1.01 1148500.0 102057.1875 0.58453176793322 1.6817 0.9554 2071194 Maybridge1_003662 Clc1ccc(cc1)C2N=C(SC(=N2)c3ccc(Cl)cc3)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O11 compound treatment 924800.0 -209000.0 -1.02 920510.0 -161000.0 -0.96 785830.0 -260612.8125 -1.49265790845621 -2.0045 -0.9794 2071195 Maybridge1_003663 CNC(=S)N/N=C(\C)/c1ccc(OC)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O12 compound treatment 1258500.0 124000.0 0.61 1165550.0 84200.0 0.5 1035040.0 -11402.8125 -0.0653095221738892 0.6022 0.7622 2071196 Maybridge1_003664 CSC1=NCN(CN1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O13 compound treatment 926140.0 -208000.0 -1.02 880800.0 -201000.0 -1.19 829930.0 -216512.8125 -1.24007549268217 -1.9912 -0.9965 2071197 Maybridge1_003665 C1Oc2ccc(cc2O1)C3Nc4ccccc4O3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O14 compound treatment 1381760.0 248000.0 1.21 1209350.0 128000.0 0.76 1020220.0 -26222.8125 -0.15019095985578 1.0513 0.7314 2071198 Maybridge1_003666 CN(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O15 compound treatment 1163260.0 29200.0 0.14 997440.0 -83900.0 -0.5 976250.0 -70192.8125 -0.402028801615075 -0.438 -0.6671 2071199 Maybridge1_003667 COc1ccc(Br)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O16 compound treatment 1349280.0 215000.0 1.05 1228110.0 147000.0 0.87 1117130.0 70687.1875 0.404860330680796 1.3445 0.9435 2071200 Maybridge1_003668 Fc1ccc(cc1)c2cn3nc(sc3n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O17 compound treatment 896640.0 -237000.0 -1.16 871650.0 -210000.0 -1.25 699240.0 -347202.8125 -1.98860147720621 -2.538 -0.9693 2071201 Maybridge1_003669 Clc1ccc2OC(Nc2c1)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O18 compound treatment 1237520.0 103000.0 0.51 1253170.0 172000.0 1.02 991070.0 -55372.8125 -0.317147363933184 0.6985 0.5904 1605476 Maybridge1_003670 Nc1ccccc1C(=O)NCc2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O19 compound treatment 575220.0 -559000.0 -2.73 581810.0 -500000.0 -2.97 447370.0 -599072.8125 -3.43118499332888 -5.2726 -0.9955 2071202 Maybridge1_003671 CCN1CNC(=NC1)SCc2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O20 compound treatment 998990.0 -135000.0 -0.66 894260.0 -187000.0 -1.11 808270.0 -238172.8125 -1.36413297852493 -1.8111 -0.9633 2071203 Maybridge1_003672 FC(F)(F)c1nnc(NC(=O)c2ccccc2NC(=O)c3ccccc3)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O21 compound treatment 804590.0 -330000.0 -1.61 760500.0 -321000.0 -1.91 633800.0 -412642.8125 -2.36340858124825 -3.3956 -0.9877 2071204 Maybridge1_003673 CCN1CNC(=NC1)SCc2ccc(Br)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O22 compound treatment 1308570.0 174000.0 0.85 1126910.0 45500.0 0.27 938880.0 -107562.8125 -0.61606519339458 0.2928 0.2696 2071205 Maybridge1_003674 O=C1NN(C(=S)Nc2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O23 mock treatment 1441960.0 308000.0 1.5 1228490.0 147000.0 0.87 1080810.0 34367.1875 0.19683780594353 1.4872 0.8492 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 O24 mock treatment 1016160.0 -118000.0 -0.58 1172160.0 90800.0 0.54 903060.0 -143382.8125 -0.821223971921256 -0.4951 -0.4346 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P01 compound treatment 1002030.0 -132000.0 -0.65 987760.0 -93600.0 -0.56 954950.0 -91492.8125 -0.524024390186214 -0.9965 -0.9961 1006990 Maybridge1_003675 CC(=O)Nc1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P02 compound treatment 901810.0 -232000.0 -1.13 1037960.0 -43400.0 -0.26 791480.0 -254962.8125 -1.46029757627655 -1.6474 -0.8822 1253391 Maybridge1_003676 CCOC(=O)c1ccc(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P03 compound treatment 34400.0 -1100000.0 -5.37 69300.0 -1010000.0 -6.02 31450.0 -1014992.8125 -5.81336364114616 -9.9331 -0.9989 2071206 Maybridge1_003677 [O-][N+](=O)c1ccc(c(Cl)c1)S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P04 compound treatment 1118620.0 -15500.0 -0.08 1098950.0 17600.0 0.1 1110400.0 63957.1875 0.366314306686253 0.2282 0.5875 1561288 Maybridge1_003678 Clc1ccccc1C(=O)N(CCC#N)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P05 compound treatment 1127940.0 -6160.0 -0.03 1050400.0 -31000.0 -0.18 862730.0 -183712.8125 -1.05221374126746 -0.7312 -0.6842 2071207 Maybridge1_003679 Oc1ccccc1/C=N/c2ccc(F)cc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P06 compound treatment 1013000.0 -121000.0 -0.59 1110680.0 29300.0 0.17 839530.0 -206912.8125 -1.18509156543884 -0.9252 -0.6925 2071208 Maybridge1_003680 NS(=O)(=O)c1ccc(Sc2ccccc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P07 compound treatment 1272900.0 139000.0 0.68 1218890.0 138000.0 0.82 989550.0 -56892.8125 -0.325853152413378 0.6755 0.6079 1034875 Maybridge1_003681 N#CC1(CCCCC1)NC2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P08 compound treatment 1274530.0 140000.0 0.69 1179370.0 98000.0 0.58 1162180.0 115737.1875 0.662883864254965 1.1153 0.9976 1017270 Maybridge1_003682 ClC(Cl)(Cl)C(=O)N1CCOCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P09 compound treatment 692720.0 -441000.0 -2.16 735140.0 -346000.0 -2.06 680010.0 -366432.8125 -2.09874115646551 -3.6455 -0.9998 1915614 Maybridge1_003683 C/C(=N\Nc1ccccc1)/c2ccc(cc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P10 compound treatment 1147420.0 13300.0 0.07 1223680.0 142000.0 0.85 1123430.0 76987.1875 0.440943532934232 0.7807 0.8163 2071209 Maybridge1_003684 Fc1ccc(cc1F)N2C(=O)C3C4CC(C=C4)C3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P11 compound treatment 1264270.0 130000.0 0.64 1217620.0 136000.0 0.81 1077680.0 31237.1875 0.178910754665236 0.9383 0.8975 2071210 Maybridge1_003685 Cc1onc(c1C(=O)N(CCC#N)C2CCCCC2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P12 compound treatment 1031360.0 -103000.0 -0.5 1098240.0 16900.0 0.1 883520.0 -162922.8125 -0.933139173831118 -0.7706 -0.7241 2071211 Maybridge1_003686 FC(F)(F)c1cccc(NC(=S)NCc2ccncc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P13 compound treatment 1004290.0 -130000.0 -0.63 980530.0 -101000.0 -0.6 888160.0 -158282.8125 -0.906563608996842 -1.2358 -0.982 2071212 Maybridge1_003687 COc1cc(/C=C\2/N3CCC(CC3)C2=O)cc(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P14 compound treatment 1088110.0 -46000.0 -0.22 1130720.0 49300.0 0.29 952230.0 -94212.8125 -0.539603169571824 -0.2718 -0.4156 1349974 Maybridge1_003688 COc1cccc(NC(=S)NCc2cccnc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P15 compound treatment 1156480.0 22400.0 0.11 1246000.0 165000.0 0.98 1014190.0 -32252.8125 -0.184727739155497 0.5217 0.5205 2071213 Maybridge1_003689 Clc1ccccc1/N=C/2\NC3(CCCCC3)C(=C)S2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P16 compound treatment 1228090.0 94000.0 0.46 1210160.0 129000.0 0.77 1064750.0 18307.1875 0.104854277659375 0.7678 0.854 2071214 Maybridge1_003690 COc1ccccc1NC(=S)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P17 compound treatment 1294400.0 160000.0 0.78 1151530.0 70200.0 0.42 1033700.0 -12742.8125 -0.0729843620182707 0.6509 0.731 2071215 Maybridge1_003691 OC(=O)c1ccc(/N=C/c2ccc3OCOc3c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P18 compound treatment 1116230.0 -17900.0 -0.09 1102480.0 21100.0 0.13 1100500.0 54057.1875 0.309612131716569 0.2008 0.5816 2071216 Maybridge1_003692 CC1CN(CC(C)O1)C(=S)Nc2cccc(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P19 compound treatment 1058690.0 -75400.0 -0.37 1059360.0 -22000.0 -0.13 917240.0 -129202.8125 -0.740008129388921 -0.7155 -0.8549 1272372 Maybridge1_003693 COc1cc(cc(OC)c1OC)C(NCc2ccccc2)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P20 compound treatment 1225390.0 91300.0 0.45 1192450.0 111000.0 0.66 1052900.0 6457.1875 0.0369834924683897 0.6602 0.8275 2071217 Maybridge1_003694 Cc1ccc(Cl)cc1NC(=S)NCc2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P21 compound treatment 1183770.0 49700.0 0.24 1163360.0 82000.0 0.49 960050.0 -86392.8125 -0.494814178838195 0.1359 0.1847 1862715 Maybridge1_003695 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P22 compound treatment 1099810.0 -34300.0 -0.17 1094180.0 12800.0 0.08 1010600.0 -35842.8125 -0.205289436947534 -0.1713 -0.6213 2071218 Maybridge1_003696 Cc1cccc(C)c1NC(=S)NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P23 mock treatment 1170560.0 36500.0 0.18 1181310.0 99900.0 0.59 1045980.0 -462.8125 -0.00265075508617748 0.4444 0.7164 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.551 P24 mock treatment 1137160.0 3060.0 0.01 991200.0 -90200.0 -0.54 994520.0 -51922.8125 -0.297387515080112 -0.4726 -0.7706 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A01 compound treatment 854500.0 -255000.0 -1.24 783040.0 -319000.0 -1.9 720220.0 -318664.375 -1.82514779271264 -2.867 -0.9848 2071219 Maybridge1_003697 Cc1ccc(NC(=S)NCc2cccnc2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A02 compound treatment 816640.0 -293000.0 -1.43 879450.0 -222000.0 -1.32 759330.0 -279554.375 -1.60114556412028 -2.5134 -0.9969 2071220 Maybridge1_003698 CCOC(=O)c1cnc(N)nc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A03 compound treatment 824480.0 -285000.0 -1.39 938200.0 -164000.0 -0.97 786840.0 -252044.375 -1.44358224761361 -2.1986 -0.9865 2071221 Maybridge1_003699 CSC(=C(C#N)c1ccc(Cl)cc1Cl)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A04 compound treatment 934200.0 -175000.0 -0.86 912660.0 -189000.0 -1.13 842050.0 -196834.375 -1.12736739104025 -1.7943 -0.9925 1658773 Maybridge1_003700 Cn1ccc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A05 compound treatment 718660.0 -391000.0 -1.91 749380.0 -352000.0 -2.1 721180.0 -317704.375 -1.8196493999883 -3.3625 -0.9982 2071222 Maybridge1_003701 Clc1ccc(NC(=O)Sc2ccccc2Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A06 compound treatment 788320.0 -321000.0 -1.57 885760.0 -216000.0 -1.29 806560.0 -232324.375 -1.33063609706793 -2.4155 -0.9961 2071223 Maybridge1_003702 CSc1cc(n[nH]1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A07 compound treatment 795610.0 -314000.0 -1.53 890720.0 -211000.0 -1.26 865370.0 -173514.375 -0.993802267778325 -2.1834 -0.9851 568 Maybridge1_003703 COc1ccc(C=C(C#N)C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A08 compound treatment 866400.0 -243000.0 -1.19 1155970.0 54100.0 0.32 967360.0 -71524.375 -0.409655315742153 -0.7358 -0.5678 2071224 Maybridge1_003704 Cc1csc(C(=O)N)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A09 compound treatment 180840.0 -928000.0 -4.54 110040.0 -992000.0 -5.9 97920.0 -940964.375 -5.38936632641309 -9.1356 -0.9944 2071225 Maybridge1_003705 NC1=C(C#N)C(C(C#N)C#N)c2cc(Br)cc(Br)c2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A10 compound treatment 1024570.0 -84700.0 -0.41 1090670.0 -11200.0 -0.07 984250.0 -54634.375 -0.312917968748419 -0.458 -0.8756 2071226 Maybridge1_003706 COC(=O)c1sc(Br)c(Br)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A11 compound treatment 264060.0 -845000.0 -4.13 163720.0 -938000.0 -5.58 255970.0 -782914.375 -4.48413614924556 -8.1939 -0.9916 2071227 Maybridge1_003707 COC(=O)C(C#N)C1C(=C(N)Oc2c(OC)cc(Br)cc12)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A12 compound treatment 631940.0 -477000.0 -2.33 712850.0 -389000.0 -2.31 640640.0 -398244.375 -2.28094163959016 -3.9989 -1.0 1192357 Maybridge1_003708 Cc1csc2ncnc(NCCc3ccc(Cl)cc3)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A13 compound treatment 939760.0 -169000.0 -0.83 920520.0 -181000.0 -1.08 923870.0 -115014.375 -0.658743961139281 -1.481 -0.9803 2071228 Maybridge1_003709 Clc1ccc(cc1)C(=O)NC2=CC3C(COC3=O)OC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A14 compound treatment 845870.0 -263000.0 -1.29 948210.0 -154000.0 -0.91 883910.0 -154974.375 -0.887614558289643 -1.7829 -0.9847 2071229 Maybridge1_003710 Nc1cc(sc1C#N)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A15 compound treatment 985040.0 -124000.0 -0.61 1043400.0 -58500.0 -0.35 984580.0 -54304.375 -0.311027896249429 -0.7307 -0.9546 1702696 Maybridge1_003711 COC(=O)c1sccc1NC(=O)CC(=O)Nc2ccsc2C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A16 compound treatment 907010.0 -202000.0 -0.99 1118090.0 16200.0 0.1 935040.0 -103844.375 -0.594767870794698 -0.8582 -0.7415 1361943 Maybridge1_003712 COC(=O)Cn1nnc(n1)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A17 compound treatment 966530.0 -143000.0 -0.7 1005760.0 -96100.0 -0.57 1011780.0 -27104.375 -0.155240102393327 -0.8222 -0.8987 1219663 Maybridge1_003713 CCOC(=O)c1c(C)csc1NC(=O)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A18 compound treatment 728230.0 -381000.0 -1.86 827170.0 -275000.0 -1.63 730140.0 -308744.375 -1.76833106789453 -3.0388 -0.9986 1116540 Maybridge1_003714 COC(=O)c1ccsc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A19 compound treatment 861220.0 -248000.0 -1.21 907120.0 -195000.0 -1.16 935470.0 -103414.375 -0.59230504905359 -1.7102 -0.962 2071230 Maybridge1_003715 CCOC(=O)c1cnn(C)c1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A20 compound treatment 865600.0 -244000.0 -1.19 1060560.0 -41300.0 -0.25 942980.0 -95904.375 -0.549291580970527 -1.1462 -0.8593 2071231 Maybridge1_003716 Clc1ccc(c2nn[nH]n2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A21 compound treatment 873140.0 -236000.0 -1.15 882720.0 -219000.0 -1.3 901190.0 -137694.375 -0.788643489251649 -1.8737 -0.9806 1669188 Maybridge1_003717 CC(C)(C)c1cc(N)c(s1)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A22 compound treatment 836900.0 -272000.0 -1.33 1033190.0 -68700.0 -0.41 985310.0 -53574.375 -0.306846826781968 -1.1812 -0.8287 2071232 Maybridge1_003718 Cn1nccc1N2C(=O)CCC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A23 mock treatment 1019050.0 -90200.0 -0.44 1067840.0 -34000.0 -0.2 1022310.0 -16574.375 -0.0949296071982991 -0.4261 -0.8622 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 A24 mock treatment 976880.0 -132000.0 -0.65 1050480.0 -51400.0 -0.31 902320.0 -136564.375 -0.782171422815715 -1.0014 -0.9448 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B01 compound treatment 1041780.0 -67500.0 -0.33 1076960.0 -24900.0 -0.15 911520.0 -127364.375 -0.729478492540857 -0.697 -0.8561 2071233 Maybridge1_003719 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B02 compound treatment 937020.0 -172000.0 -0.84 1007120.0 -94700.0 -0.56 871910.0 -166974.375 -0.956344467343806 -1.3633 -0.9787 2071234 Maybridge1_003720 Cn1ncc(C(=O)O/N=C/c2c(F)cccc2Cl)c1n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B03 compound treatment 931930.0 -177000.0 -0.87 1015390.0 -86500.0 -0.51 898800.0 -140084.375 -0.80233219613827 -1.2603 -0.9786 2071235 Maybridge1_003721 FC(F)(F)c1ccc2Oc3ccsc3C(=O)Nc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B04 compound treatment 733700.0 -376000.0 -1.83 786350.0 -316000.0 -1.88 680130.0 -358754.375 -2.05476296387775 -3.3289 -0.9988 1384033 Maybridge1_003722 CC(C)(C)c1ccc(CSc2nc(N)cc(O)n2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B05 compound treatment 934440.0 -175000.0 -0.85 988660.0 -113000.0 -0.67 902310.0 -136574.375 -0.782228697739927 -1.3334 -0.9954 2071236 Maybridge1_003723 COC(=O)CSc1ncnc2sc3CCCCc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B06 compound treatment 955000.0 -154000.0 -0.75 1081150.0 -20700.0 -0.12 912160.0 -126724.375 -0.725812897391302 -0.9253 -0.8782 2071237 Maybridge1_003724 COCCOc1ccccc1NC(=S)NNC(=O)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B07 compound treatment 797890.0 -311000.0 -1.52 878790.0 -223000.0 -1.33 746050.0 -292834.375 -1.67720666347355 -2.6125 -0.9955 1091059 Maybridge1_003725 CCOC(=O)c1ccc(NC(=S)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B08 compound treatment 913520.0 -196000.0 -0.96 992250.0 -110000.0 -0.65 913160.0 -125724.375 -0.720085404970122 -1.3442 -0.9862 2071238 Maybridge1_003726 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)Nc4ccccc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B09 compound treatment 942510.0 -167000.0 -0.81 1092160.0 -9700.0 -0.06 964320.0 -74564.375 -0.427066892702541 -0.7502 -0.814 2071239 Maybridge1_003727 COc1cc(C(=O)NNS(=O)(=O)c2cc(C)c(Cl)c(C)c2)c(cc1OC)n3c(C)ccc3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B10 compound treatment 875610.0 -234000.0 -1.14 922950.0 -179000.0 -1.06 893040.0 -145844.375 -0.835322552484268 -1.7556 -0.9919 2071240 Maybridge1_003728 FC(F)(F)Oc1ccc(cc1)c2nnc(S)n2c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B11 compound treatment 1080680.0 -28600.0 -0.14 1040610.0 -61200.0 -0.36 955080.0 -83804.375 -0.479988922674246 -0.568 -0.9184 2071241 Maybridge1_003729 C(c1nn[nH]n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B12 compound treatment 950770.0 -158000.0 -0.77 1137630.0 35800.0 0.21 1091620.0 52735.625 0.302042892513703 -0.1499 -0.1747 1919317 Maybridge1_003730 FC(F)(F)C1=Nc2ccccc2NC(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B13 compound treatment 994080.0 -115000.0 -0.56 1173460.0 71600.0 0.43 1057880.0 18995.625 0.108797298223082 -0.0162 -0.0228 1394339 Maybridge1_003731 Cc1cc(Br)ccc1S(=O)(=O)Nc2ccnn2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B14 compound treatment 800690.0 -309000.0 -1.51 844090.0 -258000.0 -1.53 775470.0 -263414.375 -1.50870383644243 -2.6264 -1.0 2071242 Maybridge1_003732 Cc1onc(c1C(=O)NC(=S)N2CCOCC2)c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B15 compound treatment 1020590.0 -88700.0 -0.43 1135360.0 33500.0 0.2 961400.0 -77484.375 -0.443791170572387 -0.3913 -0.6007 1654305 Maybridge1_003733 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Nc2ccnn2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B16 compound treatment 679110.0 -430000.0 -2.1 746790.0 -355000.0 -2.11 692530.0 -346354.375 -1.98374205785512 -3.5777 -0.9996 1322744 Maybridge1_003734 Cc1cccc(NC(=S)NC2CC3CC2C=C3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B17 compound treatment 938740.0 -171000.0 -0.83 1057790.0 -44100.0 -0.26 1081180.0 42295.625 0.242247871636581 -0.4924 -0.5433 2071243 Maybridge1_003735 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B18 compound treatment 990330.0 -119000.0 -0.58 1145560.0 43700.0 0.26 995520.0 -43364.375 -0.248369129161718 -0.3288 -0.4813 1614026 Maybridge1_003736 COc1ccc(cc1OC)c2c(C)nc3ccc(Cl)cc3c2c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B19 compound treatment 1006850.0 -102000.0 -0.5 1183100.0 81200.0 0.48 1116810.0 77925.625 0.446318426603233 0.2477 0.2998 1276489 Maybridge1_003737 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)CCC(=O)O)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B20 compound treatment 1001230.0 -108000.0 -0.53 1214750.0 113000.0 0.67 1017490.0 -21394.375 -0.122536120668388 0.0121 0.014 2071244 Maybridge1_003738 FC(F)(F)c1ccc(nc1)N2CCN(CC(=O)Nc3ccc4OCOc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B21 compound treatment 667360.0 -442000.0 -2.16 676640.0 -425000.0 -2.53 640000.0 -398884.375 -2.28460723473971 -4.0254 -0.9978 1271205 Maybridge1_003739 COc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B22 compound treatment 978840.0 -130000.0 -0.64 1254160.0 152000.0 0.91 1117660.0 78775.625 0.451186795161236 0.4155 0.3475 1738916 Maybridge1_003740 COC(=O)c1sccc1NC(=O)CC(C)(C)CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B23 mock treatment 1014780.0 -94500.0 -0.46 1116010.0 14200.0 0.08 963050.0 -75834.375 -0.43434080807744 -0.4687 -0.733 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 B24 mock treatment 905400.0 -204000.0 -1.0 1119240.0 17400.0 0.1 1000260.0 -38624.375 -0.221220815085323 -0.6431 -0.6271 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C01 compound treatment 995840.0 -113000.0 -0.55 1017780.0 -84100.0 -0.5 912090.0 -126794.375 -0.726213821860784 -1.0279 -0.987 2071245 Maybridge1_003741 Cc1ccccc1NC(=S)NCc2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C02 compound treatment 954780.0 -154000.0 -0.75 980530.0 -121000.0 -0.72 907450.0 -131434.375 -0.752789386695061 -1.2869 -0.9998 2071246 Maybridge1_003742 COC(=O)c1scc(C)c1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C03 compound treatment 790260.0 -319000.0 -1.56 730730.0 -371000.0 -2.21 701360.0 -337524.375 -1.93316829977609 -3.2901 -0.9904 2071247 Maybridge1_003743 Cc1onc(c1C(=O)Oc2cc(nn2C)C(F)(F)F)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C04 compound treatment 1058080.0 -51200.0 -0.25 1024640.0 -77200.0 -0.46 956080.0 -82804.375 -0.474261430253066 -0.6833 -0.968 2071248 Maybridge1_003744 C(c1nn[nH]n1)c2nc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C05 compound treatment 1007710.0 -102000.0 -0.5 1074980.0 -26900.0 -0.16 964700.0 -74184.375 -0.424890445582492 -0.624 -0.928 2071249 Maybridge1_003745 CCOC(=O)c1cnn(c1N)c2c([N+](=O)[O-])c(C)nn2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C06 compound treatment 965570.0 -144000.0 -0.7 1175450.0 73600.0 0.44 1022450.0 -16434.375 -0.0941277582593339 -0.207 -0.2486 2071250 Maybridge1_003746 Cn1ncc2c(=O)[nH]cnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C07 compound treatment 1025340.0 -83900.0 -0.41 1134910.0 33100.0 0.2 898010.0 -140874.375 -0.806856915151002 -0.5891 -0.636 1505403 Maybridge1_003747 O=C1CCc2ccccc2N1Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C08 compound treatment 941060.0 -168000.0 -0.82 974500.0 -127000.0 -0.76 850170.0 -188714.375 -1.08086015258026 -1.5357 -0.9878 1586389 Maybridge1_003748 CCCc1nc(N)ncc1C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C09 compound treatment 1002040.0 -107000.0 -0.52 949830.0 -152000.0 -0.9 896390.0 -142494.375 -0.816135452873314 -1.2956 -0.9772 1045287 Maybridge1_003749 COC(=O)C1CCC(CC1)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C10 compound treatment 1057630.0 -51600.0 -0.25 1157770.0 55900.0 0.33 1059410.0 20525.625 0.117560361627488 0.1142 0.2634 2071251 Maybridge1_003750 NNC(=O)c1cnn(c1C(F)(F)F)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C11 compound treatment 749500.0 -360000.0 -1.76 824390.0 -277000.0 -1.65 709480.0 -329404.375 -1.88666106131611 -3.0567 -0.9985 2071252 Maybridge1_003751 COC(=O)C(C#N)C1C(=C(N)Oc2c(Br)cc(Br)cc12)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C12 compound treatment 925350.0 -184000.0 -0.9 934430.0 -167000.0 -1.0 902940.0 -135944.375 -0.778620377514583 -1.5431 -0.9951 2071253 Maybridge1_003752 COC(=O)c1sccc1Oc2ccc(cc2NS(=O)(=O)c3ccc(F)cc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C13 compound treatment 1045920.0 -63300.0 -0.31 1253280.0 151000.0 0.9 1133120.0 94235.625 0.539733827992682 0.6528 0.5965 2071254 Maybridge1_003753 Cc1ccc(OCC2SCCN2C(=O)c3ccc(F)cc3)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C14 compound treatment 1126480.0 17200.0 0.08 1213440.0 112000.0 0.66 1101380.0 62495.625 0.357943218544422 0.6383 0.8415 2071255 Maybridge1_003754 CCOc1ccsc1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C15 compound treatment 837780.0 -271000.0 -1.33 897230.0 -205000.0 -1.22 819140.0 -219744.375 -1.25858424240949 -2.195 -0.9994 2071256 Maybridge1_003755 CCOC(=O)c1c(C)csc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C16 compound treatment 931220.0 -178000.0 -0.87 1048270.0 -53600.0 -0.32 945500.0 -93384.375 -0.534858300069153 -0.995 -0.9302 2071257 Maybridge1_003756 Cc1csc2c(S)ncnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C17 compound treatment 932890.0 -176000.0 -0.86 1112640.0 10800.0 0.06 935220.0 -103664.375 -0.593736922158886 -0.8033 -0.7662 2071258 Maybridge1_003757 Nc1c(C#N)cnc2c(Br)cnn12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C18 compound treatment 983040.0 -126000.0 -0.62 1250150.0 148000.0 0.88 1061670.0 22785.625 0.130504494499355 0.2284 0.2107 1400072 Maybridge1_003758 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(c2ccc(F)cc2F)S(=O)(=O)c3ccc(NC(=O)C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C19 compound treatment 900960.0 -208000.0 -1.02 1092000.0 -9860.0 -0.06 1199420.0 160535.625 0.919466575516932 -0.0906 -0.066 1647208 Maybridge1_003759 CCOC(=O)c1c(C)csc1NC(=O)Nc2c(C)onc2c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C20 compound treatment 903590.0 -206000.0 -1.0 1124700.0 22800.0 0.14 964260.0 -74624.375 -0.427410542247812 -0.7485 -0.6802 2071259 Maybridge1_003760 Clc1ccc(cc1Cl)c2nn[nH]n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C21 compound treatment 829170.0 -280000.0 -1.37 1064650.0 -37200.0 -0.22 859940.0 -178944.375 -1.02490255162533 -1.5095 -0.8756 2071260 Maybridge1_003761 CC(=O)c1sc(cc1N)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C22 compound treatment 1046830.0 -62400.0 -0.31 1202210.0 100000.0 0.6 1094670.0 55785.625 0.319511744398302 0.3529 0.4753 2071261 Maybridge1_003762 CCOC(=O)c1ccsc1NC(=O)c2ccc(cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C23 mock treatment 1028610.0 -80600.0 -0.39 1124640.0 22800.0 0.14 1079700.0 40815.625 0.233771182853234 -0.0143 -0.0299 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 C24 mock treatment 1005620.0 -104000.0 -0.51 1085660.0 -16200.0 -0.1 926650.0 -112234.375 -0.6428215322084 -0.7191 -0.8727 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D01 compound treatment 1019050.0 -90200.0 -0.44 1102140.0 283.0 0.0 1017130.0 -21754.375 -0.124598017940013 -0.3254 -0.7105 1343139 Maybridge1_003763 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(F)c(F)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D02 compound treatment 933680.0 -176000.0 -0.86 995960.0 -106000.0 -0.63 859140.0 -179744.375 -1.02948454556228 -1.4532 -0.9815 1490566 Maybridge1_003764 Cc1onc(c1C(=O)Nc2ccccc2)c3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D03 compound treatment 951150.0 -158000.0 -0.77 985840.0 -116000.0 -0.69 853070.0 -185814.375 -1.06425042455884 -1.4588 -0.9823 1387616 Maybridge1_003765 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cccc(C)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D04 compound treatment 1002720.0 -107000.0 -0.52 1054480.0 -47400.0 -0.28 977280.0 -61604.375 -0.352838590924045 -0.6669 -0.9678 2071262 Maybridge1_003766 Oc1cc(O)nc(SCc2c(Cl)cccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D05 compound treatment 774650.0 -335000.0 -1.63 831080.0 -271000.0 -1.61 758080.0 -280804.375 -1.60830492964675 -2.8021 -1.0 1544193 Maybridge1_003767 COc1cc2ncnc(Sc3ccc(C)cc3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D06 compound treatment 1075050.0 -34200.0 -0.17 1000560.0 -101000.0 -0.6 983520.0 -55364.375 -0.31709903821588 -0.6273 -0.895 2071263 Maybridge1_003768 COC(=O)c1ccccc1NC(=S)NNC(=O)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D07 compound treatment 872390.0 -237000.0 -1.16 930880.0 -171000.0 -1.02 809280.0 -229604.375 -1.31505731768232 -2.0144 -0.9946 2071264 Maybridge1_003769 Cn1nccc1NC(=O)Nc2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D08 compound treatment 997280.0 -112000.0 -0.55 1111120.0 9260.0 0.06 935250.0 -103634.375 -0.59356509738625 -0.6268 -0.7746 2071265 Maybridge1_003770 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)Nc4cc(Cl)cc(Cl)c4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D09 compound treatment 973500.0 -136000.0 -0.66 1013550.0 -88300.0 -0.53 847600.0 -191284.375 -1.0955798081027 -1.3187 -0.9527 2071266 Maybridge1_003771 Cc1ccc(C)n1c2sc3CCCCc3c2C(=O)NNC(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D10 compound treatment 1026480.0 -82800.0 -0.4 1056580.0 -45300.0 -0.27 941790.0 -97094.375 -0.556107296951731 -0.71 -0.9615 2071267 Maybridge1_003772 FC(F)(F)c1ccc(OCC#N)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D11 compound treatment 1153880.0 44600.0 0.22 1112410.0 10600.0 0.06 1116870.0 77985.625 0.446662076148504 0.42 0.8383 1194918 Maybridge1_003773 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D12 compound treatment 753140.0 -356000.0 -1.74 790960.0 -311000.0 -1.85 678370.0 -360514.375 -2.06484335053903 -3.2641 -0.9974 2071268 Maybridge1_003774 CCOC(=O)c1c(N)scc1c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D13 compound treatment 1105320.0 -3940.0 -0.02 1333310.0 231000.0 1.38 969090.0 -69794.375 -0.399746753853511 0.5527 0.3856 1589664 Maybridge1_003775 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)on3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D14 compound treatment 961960.0 -147000.0 -0.72 1046200.0 -55700.0 -0.33 1080360.0 41475.625 0.237551327851213 -0.4694 -0.5676 1122688 Maybridge1_003776 CC1CCCC(C)N1C(=S)NC(=O)c2c(C)onc2c3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D15 compound treatment 1040810.0 -68400.0 -0.33 1426020.0 324000.0 1.93 1190930.0 152045.625 0.870840164861112 1.4226 0.6643 2071269 Maybridge1_003777 Clc1ccc(CSc2ncnc3sc4CCCCc4c23)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D16 compound treatment 1033860.0 -75400.0 -0.37 1300250.0 198000.0 1.18 1128160.0 89275.625 0.511325465583628 0.7637 0.571 2071270 Maybridge1_003778 S=C(NC1CC2CC1C=C2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D17 compound treatment 1112860.0 3600.0 0.02 1343060.0 241000.0 1.43 940490.0 -98394.375 -0.563553037099266 0.5129 0.3328 1545146 Maybridge1_003779 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc4ccccc4c3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D18 compound treatment 869690.0 -240000.0 -1.17 910280.0 -192000.0 -1.14 713140.0 -325744.375 -1.86569843905459 -2.4107 -0.9722 1144861 Maybridge1_003780 CCN(CC)c1ccc(NC(=S)Nc2ccc(OC)cc2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D19 compound treatment 1002080.0 -107000.0 -0.52 1097120.0 -4740.0 -0.03 972900.0 -65984.375 -0.377925007728814 -0.5368 -0.8304 1466175 Maybridge1_003781 COc1cc(NC(=O)c2ccccc2)c(cc1OC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D20 compound treatment 791170.0 -318000.0 -1.55 988380.0 -113000.0 -0.67 910160.0 -128724.375 -0.737267882233662 -1.7125 -0.9268 1146514 Maybridge1_003782 Cc1cc(N2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)c4ccccc4n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D21 compound treatment 607210.0 -502000.0 -2.45 663360.0 -438000.0 -2.61 589700.0 -449184.375 -2.57270010352508 -4.407 -0.9997 2071271 Maybridge1_003783 COc1cc2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D22 compound treatment 811890.0 -297000.0 -1.45 1088000.0 -13900.0 -0.08 946750.0 -92134.375 -0.527698934542677 -1.1911 -0.7695 2071272 Maybridge1_003784 C1Oc2ccc(/N=C/3\SCC4CCCCN43)cc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D23 mock treatment 1047860.0 -61400.0 -0.3 1167680.0 65800.0 0.39 1055400.0 16515.625 0.0945931170185548 0.1074 0.2139 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 D24 mock treatment 1028960.0 -80300.0 -0.39 1149240.0 47400.0 0.28 996030.0 -42854.375 -0.245448108026916 -0.2055 -0.3794 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E01 compound treatment 1012350.0 -96900.0 -0.47 1085230.0 -16600.0 -0.1 1020540.0 -18344.375 -0.105067268783788 -0.3911 -0.7902 1546515 Maybridge1_003785 Cc1ccc(NC(=S)N(CCC#N)CCc2ccccn2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E02 compound treatment 1112370.0 3110.0 0.02 1085120.0 -16700.0 -0.1 946930.0 -91954.375 -0.526667985906865 -0.3528 -0.6579 1704263 Maybridge1_003786 CCOC(=O)CC(=O)Nc1c(C)csc1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E03 compound treatment 1204640.0 95400.0 0.47 1065990.0 -35900.0 -0.21 913000.0 -125884.375 -0.72100180375751 -0.2703 -0.3056 1427173 Maybridge1_003787 COc1ccc(Cc2n[nH]c(=O)o2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E04 compound treatment 1198810.0 89600.0 0.44 1094780.0 -7080.0 -0.04 909470.0 -129414.375 -0.741219852004277 -0.1996 -0.2316 2071273 Maybridge1_003788 OC(=O)c1cnn(c1C(F)(F)F)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E05 compound treatment 1100080.0 -9180.0 -0.04 1231050.0 129000.0 0.77 1050480.0 11595.625 0.066413854306348 0.456 0.5904 2071274 Maybridge1_003789 Cc1nn(C)c(c1[N+](=O)[O-])n2ncc(C#N)c2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E06 compound treatment 1243680.0 134000.0 0.66 1149070.0 47200.0 0.28 1064230.0 25345.625 0.145166875097576 0.6251 0.8576 2071275 Maybridge1_003790 COC(=O)CSc1ncnc2c(C)csc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E07 compound treatment 1230300.0 121000.0 0.59 1153280.0 51400.0 0.31 912850.0 -126034.375 -0.721860927620687 0.1012 0.1031 2071276 Maybridge1_003791 CCOC(=O)C1=C(C)N=C2SCCC(=O)N2C1c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E08 compound treatment 770330.0 -339000.0 -1.66 848290.0 -254000.0 -1.51 682520.0 -356364.375 -2.04107425699113 -3.005 -0.9917 1257517 Maybridge1_003792 Clc1ccc(NC(=O)C2CCc3ccccc3O2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E09 compound treatment 847840.0 -261000.0 -1.28 860600.0 -241000.0 -1.43 689390.0 -349494.375 -2.00172638405762 -2.7214 -0.981 1196450 Maybridge1_003793 COc1ccc2-c3nc(N)sc3CCc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E10 compound treatment 1062560.0 -46700.0 -0.23 1248660.0 147000.0 0.87 1076480.0 37595.625 0.215328657257034 0.4966 0.5354 2071277 Maybridge1_003794 COC(=O)c1sccc1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E11 compound treatment 709660.0 -400000.0 -1.95 709280.0 -393000.0 -2.33 648270.0 -390614.375 -2.23724087241655 -3.7667 -0.9972 2071278 Maybridge1_003795 COc1ccc(/C=C(\C#N)/c2nc3ccccc3[nH]2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E12 compound treatment 38030.0 -1070000.0 -5.23 55840.0 -1050000.0 -6.22 44800.0 -994084.375 -5.69361072382619 -9.9002 -0.9975 2071279 Maybridge1_003796 COC(=O)c1scc(C)c1N2C(=O)C=CC2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E13 compound treatment 1259770.0 151000.0 0.74 1331440.0 230000.0 1.37 954580.0 -84304.375 -0.482852668884836 0.934 0.5751 2071280 Maybridge1_003797 OC(=O)c1ccccc1SCC(=O)c2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E14 compound treatment 1189000.0 79700.0 0.39 1277250.0 175000.0 1.04 1181230.0 142345.625 0.815283488375663 1.2978 0.9405 2071281 Maybridge1_003798 CCOc1ccsc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E15 compound treatment 1028730.0 -80500.0 -0.39 1162690.0 60800.0 0.36 935360.0 -103524.375 -0.59293507321992 -0.3606 -0.4518 2071282 Maybridge1_003799 CC(=O)CSc1ccc(cc1[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E16 compound treatment 962420.0 -147000.0 -0.72 1013660.0 -88200.0 -0.52 930760.0 -108124.375 -0.619281538357349 -1.0745 -0.992 2071283 Maybridge1_003800 CCOC(=O)c1cc2c(nn(C)c2s1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E17 compound treatment 818190.0 -291000.0 -1.42 933770.0 -168000.0 -1.0 831120.0 -207764.375 -1.18996888320375 -2.0852 -0.9899 1108872 Maybridge1_003801 N#CCc1nc2ccccc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E18 compound treatment 695110.0 -414000.0 -2.02 771640.0 -330000.0 -1.96 713320.0 -325564.375 -1.86466749041878 -3.3785 -0.9994 2071284 Maybridge1_003802 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(c2ccccc2C(F)(F)F)S(=O)(=O)c3ccc(NC(=O)C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E19 compound treatment 1057020.0 -52200.0 -0.26 1193760.0 91900.0 0.55 1080190.0 41305.625 0.236577654139613 0.3048 0.4704 2071285 Maybridge1_003803 CCOC(=O)c1c(C)csc1NC(=O)Nc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E20 compound treatment 1065340.0 -43900.0 -0.21 1189460.0 87600.0 0.52 986370.0 -52514.375 -0.300775684815517 0.0032 0.0051 2071286 Maybridge1_003804 Clc1cccc(Cl)c1c2nn[nH]n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E21 compound treatment 828910.0 -280000.0 -1.37 921400.0 -180000.0 -1.07 818300.0 -220584.375 -1.26339533604328 -2.1398 -0.9951 1360504 Maybridge1_003805 CC(C)(C)c1cc(NC(=O)CC#N)c(s1)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E22 compound treatment 405520.0 -704000.0 -3.44 446650.0 -655000.0 -3.9 399620.0 -639264.375 -3.66138186294302 -6.3485 -0.9987 1513979 Maybridge1_003806 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E23 mock treatment 1083140.0 -26100.0 -0.13 1179210.0 77400.0 0.46 1004350.0 -34534.375 -0.197795371082696 0.0777 0.1504 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 E24 mock treatment 1103280.0 -5980.0 -0.03 1108430.0 6570.0 0.04 1022730.0 -16154.375 -0.0925240603814034 -0.0477 -0.4561 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F01 compound treatment 982560.0 -127000.0 -0.62 994560.0 -107000.0 -0.64 867730.0 -171154.375 -0.980285385664339 -1.2917 -0.9761 1584709 Maybridge1_003807 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F02 compound treatment 1029510.0 -79700.0 -0.39 1050610.0 -51200.0 -0.3 930030.0 -108854.375 -0.623462607824811 -0.7609 -0.956 2071287 Maybridge1_003808 CCOC(=O)C(=CNNC(=O)c1cnn(c1C(F)(F)F)c2ccc(cc2)[N+](=O)[O-])C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F03 compound treatment 933470.0 -176000.0 -0.86 890490.0 -211000.0 -1.26 753300.0 -285584.375 -1.63568234341999 -2.1659 -0.9693 1486847 Maybridge1_003809 O=c1[nH]cnc2sc3CCCCc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F04 compound treatment 1042240.0 -67000.0 -0.33 976370.0 -125000.0 -0.75 809370.0 -229514.375 -1.31454184336442 -1.3788 -0.8915 1945423 Maybridge1_003810 Nc1cc(O)nc(SCc2ccc(Cl)cc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F05 compound treatment 673320.0 -436000.0 -2.13 649950.0 -452000.0 -2.69 615130.0 -423754.375 -2.42704997125447 -4.1825 -0.9956 2071288 Maybridge1_003811 COc1ncnc2sc3CCCCc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F06 compound treatment 639250.0 -470000.0 -2.3 626510.0 -475000.0 -2.83 530210.0 -508674.375 -2.91342862766109 -4.6399 -0.9949 2071289 Maybridge1_003812 Cc1csc(N)c1c2nc3ccccc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F07 compound treatment 999900.0 -109000.0 -0.53 1125990.0 24100.0 0.14 937220.0 -101664.375 -0.582281937316525 -0.5618 -0.6995 2071290 Maybridge1_003813 Cn1nccc1NC(=O)Nc2cccc(Br)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F08 compound treatment 708180.0 -401000.0 -1.96 679800.0 -422000.0 -2.51 652380.0 -386504.375 -2.2137008785655 -3.8585 -0.9949 2071291 Maybridge1_003814 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)Nc4ccc(F)cc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F09 compound treatment 1109240.0 -16.1 0.0 1075680.0 -26200.0 -0.16 911520.0 -127364.375 -0.729478492540857 -0.5111 -0.6852 1728277 Maybridge1_003815 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F10 compound treatment 1117050.0 7790.0 0.04 980550.0 -121000.0 -0.72 952210.0 -86674.375 -0.496426825923033 -0.6811 -0.7771 2071292 Maybridge1_003816 Nc1ccccc1Sc2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F11 compound treatment 1035840.0 -73400.0 -0.36 1116880.0 15000.0 0.09 894560.0 -144324.375 -0.826616764004074 -0.6328 -0.6988 1590495 Maybridge1_003817 Cc1cc(c(C)cc1Cl)S(=O)(=O)Nc2ccnn2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F12 compound treatment 1067680.0 -41600.0 -0.2 1092640.0 -9220.0 -0.05 857120.0 -181764.375 -1.04105408025306 -0.75 -0.7061 2071293 Maybridge1_003818 O=c1[nH]cnc2scc(c3ccccc3)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F13 compound treatment 1473680.0 364000.0 1.78 1234270.0 132000.0 0.79 1090150.0 51265.625 0.293623478654568 1.6521 0.8391 1333321 Maybridge1_003819 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3cccc(Cl)c3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F14 compound treatment 826240.0 -283000.0 -1.38 872000.0 -230000.0 -1.37 749600.0 -289284.375 -1.65687406537836 -2.5441 -0.9959 1199492 Maybridge1_003820 CC1CCN(CC1)C(=S)NC2CC3CCC2C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F15 compound treatment 1221280.0 112000.0 0.55 1250830.0 149000.0 0.89 940870.0 -98014.375 -0.561376589979217 0.5034 0.4255 1180444 Maybridge1_003821 COc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)on3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F16 compound treatment 1138720.0 29500.0 0.14 1105850.0 3990.0 0.02 1082240.0 43355.625 0.248319013603032 0.2402 0.834 1218416 Maybridge1_003822 CCOc1ccc(NC(=S)NC2CC3CC2C=C3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F17 compound treatment 805310.0 -304000.0 -1.49 477940.0 -624000.0 -3.71 760830.0 -278054.375 -1.59255432548851 -3.9189 -0.911 1356531 Maybridge1_003823 COc1cc(NC(=O)c2ccc(Cl)cc2)c(cc1OC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F18 compound treatment 1015230.0 -94000.0 -0.46 1013680.0 -88200.0 -0.52 904530.0 -134354.375 -0.769513664564907 -1.0122 -0.9749 1299812 Maybridge1_003824 NC(=O)c1c(N)sc2CCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F19 compound treatment 1175050.0 65800.0 0.32 1128000.0 26100.0 0.16 1061600.0 22715.625 0.130103570029872 0.3505 0.9222 1679441 Maybridge1_003825 COc1cc(NC(=O)c2cccs2)c(cc1OC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F20 compound treatment 899840.0 -209000.0 -1.02 1198810.0 97000.0 0.58 1061120.0 22235.625 0.127354373667706 -0.1843 -0.156 1704487 Maybridge1_003826 Cc1cc(N2CCN(CC2)S(=O)(=O)c3ccc(F)cc3)c4ccccc4n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F21 compound treatment 1098020.0 -11200.0 -0.05 1388610.0 287000.0 1.71 1206990.0 168105.625 0.962823693145266 1.5087 0.7701 2071294 Maybridge1_003827 CC(=O)c1sc(cc1NC(=O)c2ccc(Cl)cc2)c3ccc(cc3)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F22 compound treatment 1039080.0 -70200.0 -0.34 1416660.0 315000.0 1.87 1164900.0 126015.625 0.72175353713779 1.2995 0.6385 2071295 Maybridge1_003828 Cc1scc(NS(=O)(=O)c2ccc(C)cc2)c1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F23 mock treatment 1029440.0 -79800.0 -0.39 1136090.0 34200.0 0.2 992270.0 -46614.375 -0.266983479530553 -0.2618 -0.5087 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 F24 mock treatment 1143520.0 34300.0 0.17 1063710.0 -38100.0 -0.23 1043100.0 4215.625 0.0241449602380379 -0.0204 -0.072 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G01 compound treatment 1030580.0 -78700.0 -0.38 1010560.0 -91300.0 -0.54 877860.0 -161024.375 -0.922265887437784 -1.0678 -0.9391 2071296 Maybridge1_003829 FC(F)(F)c1cccc(NC(=S)N(CCC#N)CCc2ccccn2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G02 compound treatment 1158610.0 49400.0 0.24 1072680.0 -29200.0 -0.17 937130.0 -101754.375 -0.582797411634431 -0.2974 -0.4547 2071297 Maybridge1_003830 COC(=O)c1sccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G03 compound treatment 750600.0 -359000.0 -1.75 693680.0 -408000.0 -2.43 675800.0 -363084.375 -2.07956300606146 -3.6137 -0.9914 2071298 Maybridge1_003831 CSc1cc(n[nH]1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G04 compound treatment 1199390.0 90100.0 0.44 1037730.0 -64100.0 -0.38 911680.0 -127204.375 -0.728562093753468 -0.3865 -0.4144 2071299 Maybridge1_003832 CCCc1c(cnn1c2ccccc2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G05 compound treatment 1102720.0 -6540.0 -0.03 974310.0 -128000.0 -0.76 981550.0 -57334.375 -0.328382198285605 -0.6459 -0.7809 1059689 Maybridge1_003833 CCOC(=O)c1cnn(C)c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G06 compound treatment 1168040.0 58800.0 0.29 1072320.0 -29500.0 -0.18 916440.0 -122444.375 -0.70129922982865 -0.3405 -0.4377 2071300 Maybridge1_003834 Cc1csc2c(SCC(=O)NN)ncnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G07 compound treatment 1384130.0 275000.0 1.34 1127720.0 25900.0 0.15 925760.0 -113124.375 -0.647919000463251 0.4901 0.3269 1006328 Maybridge1_003835 OC(=O)C1CCC(CC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G08 compound treatment 981170.0 -128000.0 -0.63 857380.0 -244000.0 -1.45 812980.0 -225904.375 -1.29386559572396 -1.9477 -0.9527 2071301 Maybridge1_003836 N/C(=N/OC(=O)C1CCc2ccccc2O1)/c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G09 compound treatment 898470.0 -211000.0 -1.03 885020.0 -217000.0 -1.29 749240.0 -289644.375 -1.65893596264999 -2.2968 -0.9816 1162404 Maybridge1_003837 Nc1nc-2c(CCc3ccccc23)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G10 compound treatment 1335040.0 226000.0 1.1 1155520.0 53700.0 0.32 1216800.0 177915.625 1.01901039379704 1.4095 0.918 2071302 Maybridge1_003838 NNC(=O)c1cnn(c1C(F)(F)F)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G11 compound treatment 612020.0 -497000.0 -2.43 518570.0 -583000.0 -3.47 419860.0 -619024.375 -3.54545741633833 -5.4522 -0.9872 2071303 Maybridge1_003839 Clc1ccc(cc1)C(=O)ON=C2C3CC4CC(C3)CC2C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G12 compound treatment 1214260.0 105000.0 0.51 1335010.0 233000.0 1.39 1249490.0 210605.625 1.20624212104543 1.7931 0.9398 2071304 Maybridge1_003840 COC(=O)c1scc(N)c1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G13 compound treatment 992760.0 -116000.0 -0.57 1012870.0 -89000.0 -0.53 851000.0 -187884.375 -1.07610633387068 -1.2554 -0.9458 2071305 Maybridge1_003841 CCOC(=O)c1csc(N/N=C/2\CCCc3cc(OC)ccc23)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G14 compound treatment 1142310.0 33100.0 0.16 1314640.0 213000.0 1.27 1296170.0 257285.625 1.47360146726612 1.6746 0.8592 1415299 Maybridge1_003842 CCOc1ccsc1C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G15 compound treatment 1056820.0 -52400.0 -0.26 1054530.0 -47300.0 -0.28 980480.0 -58404.375 -0.334510615176268 -0.5035 -0.9938 1245805 Maybridge1_003843 COC(=O)c1ccccc1NC(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G16 compound treatment 1174560.0 65300.0 0.32 1068830.0 -33000.0 -0.2 1066500.0 27615.625 0.158168282893655 0.1621 0.3987 1626184 Maybridge1_003844 COC(=O)C1=C(N)CCS1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G17 compound treatment 1273930.0 165000.0 0.8 1308010.0 206000.0 1.23 961360.0 -77524.375 -0.444020270269234 0.9159 0.5978 2071306 Maybridge1_003845 O=c1nc[nH]c2ccsc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G18 compound treatment 1106340.0 -2920.0 -0.01 1176380.0 74500.0 0.44 1091730.0 52845.625 0.302672916680033 0.4224 0.7868 2071307 Maybridge1_003846 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(NC(=O)C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G19 compound treatment 1201950.0 92700.0 0.45 1071000.0 -30900.0 -0.18 989700.0 -49184.375 -0.281703135052987 -0.0071 -0.0126 1512183 Maybridge1_003847 CCOC(=O)CC(=O)Nc1scc(C)c1C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G20 compound treatment 1181120.0 71900.0 0.35 1328980.0 227000.0 1.35 1120000.0 81115.625 0.464589127426798 1.2507 0.8504 2071308 Maybridge1_003848 CC(C)(C)c1ccc(cc1)c2nnnn2Cc3c(Cl)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G21 compound treatment 1247410.0 138000.0 0.67 1250530.0 149000.0 0.88 1096180.0 57295.625 0.328160257954285 1.0896 0.9395 1630143 Maybridge1_003849 CCOC(=O)c1cnn(C)c1NC(=O)c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G22 compound treatment 1208320.0 99100.0 0.48 1275120.0 173000.0 1.03 1113010.0 74125.625 0.424553955402748 1.1194 0.9214 2071309 Maybridge1_003850 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G23 mock treatment 1075470.0 -33800.0 -0.17 1154630.0 52800.0 0.31 1010270.0 -28614.375 -0.163888615949309 -0.0087 -0.0224 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 G24 mock treatment 1070410.0 -38800.0 -0.19 1158880.0 57000.0 0.34 1103220.0 64335.625 0.368481804599394 0.2989 0.5582 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H01 compound treatment 1045850.0 -63400.0 -0.31 997090.0 -105000.0 -0.62 963260.0 -75624.375 -0.433138034668992 -0.7886 -0.9622 1247158 Maybridge1_003851 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2cc(Cl)cc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H02 compound treatment 1374590.0 265000.0 1.3 1115720.0 13900.0 0.08 1004450.0 -34434.375 -0.197222621840578 0.6822 0.5192 2071310 Maybridge1_003852 Cc1ccc(cc1)c2nnc(o2)c3cnn(c3C(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H03 compound treatment 1059160.0 -50100.0 -0.24 1027050.0 -74800.0 -0.44 905120.0 -133764.375 -0.766134444036411 -0.8405 -0.9144 1273506 Maybridge1_003853 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H04 compound treatment 1275230.0 166000.0 0.81 971950.0 -130000.0 -0.77 883080.0 -155804.375 -0.892368376999223 -0.493 -0.3443 1004482 Maybridge1_003854 CC(=O)CC(=O)Nc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H05 compound treatment 875480.0 -234000.0 -1.14 864000.0 -238000.0 -1.41 789150.0 -249734.375 -1.43035174012068 -2.3019 -0.9951 2071311 Maybridge1_003855 COc1cc2ncnc(Sc3ccc(Cl)cc3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H06 compound treatment 1335000.0 226000.0 1.1 1140360.0 38500.0 0.23 1036590.0 -2294.375 -0.0131410154238454 0.7614 0.6759 2071312 Maybridge1_003856 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)S(=O)(=O)c4ccc(C)cc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H07 compound treatment 1407240.0 298000.0 1.46 1049630.0 -52200.0 -0.31 1001140.0 -37744.375 -0.216180621754685 0.5364 0.3566 2071313 Maybridge1_003857 Cn1nccc1NC(=S)Nc2ccc(Br)cc2OC(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H08 compound treatment 897570.0 -212000.0 -1.03 809830.0 -292000.0 -1.74 864640.0 -174244.375 -0.997983337245786 -2.1759 -0.9653 2071314 Maybridge1_003858 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=S)Nc4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H09 compound treatment 1334240.0 225000.0 1.1 1046660.0 -55200.0 -0.33 1030400.0 -8484.375 -0.048594193510951 0.4171 0.3632 1333925 Maybridge1_003859 COc1cccc(OC)c1C(=O)Nc2ccnn2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H10 compound treatment 1491130.0 382000.0 1.87 1096640.0 -5220.0 -0.03 979800.0 -59084.375 -0.338405310022671 0.8639 0.4555 2071315 Maybridge1_003860 N/C(=N/O)/Cn1ccc(n1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H11 compound treatment 1412960.0 304000.0 1.48 1158720.0 56900.0 0.34 930800.0 -108084.375 -0.619052438660502 0.6945 0.4227 2071316 Maybridge1_003861 Cn1nccc1NC(=O)CCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H12 compound treatment 1267920.0 159000.0 0.78 1201070.0 99200.0 0.59 1021640.0 -17244.375 -0.0987670271204899 0.7312 0.7467 2071317 Maybridge1_003862 CC1(C)COCCN1C(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H13 compound treatment 1400180.0 291000.0 1.42 1234650.0 133000.0 0.79 1137070.0 98185.625 0.562357423056344 1.6012 0.9307 1484331 Maybridge1_003863 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(C#N)cc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H14 compound treatment 996580.0 -113000.0 -0.55 1168880.0 67000.0 0.4 926080.0 -112804.375 -0.646086202888473 -0.4608 -0.4913 1510294 Maybridge1_003864 CCC(CO)NC(=S)NC1CC2CCC1C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H15 compound treatment 713980.0 -395000.0 -1.93 739920.0 -362000.0 -2.15 729280.0 -309604.375 -1.77325671137674 -3.3814 -0.9968 1985554 Maybridge1_003865 CCSc1ncnc2sc3CCCCc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H16 compound treatment 794240.0 -315000.0 -1.54 783470.0 -318000.0 -1.89 760400.0 -278484.375 -1.59501714722961 -2.9026 -0.9957 1390457 Maybridge1_003866 CCOc1ccccc1NC(=S)NC2CC3CCC2C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H17 compound treatment 725290.0 -384000.0 -1.88 529440.0 -572000.0 -3.4 705510.0 -333374.375 -1.9093992062282 -4.1507 -0.9585 2071318 Maybridge1_003867 COc1cc(NC(=O)c2ccc(OC(F)(F)F)cc2)c(cc1OC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H18 compound treatment 747490.0 -362000.0 -1.77 752100.0 -350000.0 -2.08 588290.0 -450594.375 -2.58077586783894 -3.7113 -0.988 1566872 Maybridge1_003868 COc1cccc(NC(=S)Nc2ccccc2n3cccc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H19 compound treatment 1019930.0 -89300.0 -0.44 928960.0 -173000.0 -1.03 882630.0 -156254.375 -0.894945748588754 -1.3623 -0.9518 2071319 Maybridge1_003869 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CN2CCNCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H20 compound treatment 878200.0 -231000.0 -1.13 913400.0 -188000.0 -1.12 850430.0 -188454.375 -1.07937100455076 -1.922 -0.9998 1337960 Maybridge1_003870 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H21 compound treatment 242410.0 -867000.0 -4.24 413250.0 -689000.0 -4.09 403440.0 -635444.375 -3.63950284189411 -6.9107 -0.998 1393179 Maybridge1_003871 CC(=O)Nc1cc(sc1C(=O)N)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H22 compound treatment 834330.0 -275000.0 -1.34 978580.0 -123000.0 -0.73 691950.0 -346934.375 -1.9870640034594 -2.346 -0.9354 1363593 Maybridge1_003872 Cc1cc(Cl)ccc1Nc2nnns2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H23 mock treatment 1116320.0 7060.0 0.03 1116030.0 14200.0 0.08 996720.0 -42164.375 -0.241496138256301 -0.0708 -0.2745 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 H24 mock treatment 1193320.0 84100.0 0.41 1164120.0 62300.0 0.37 961890.0 -76994.375 -0.440984699286009 0.1963 0.2775 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I01 compound treatment 1123220.0 14000.0 0.07 984640.0 -117000.0 -0.7 877760.0 -161124.375 -0.922838636679902 -0.8958 -0.7733 2071320 Maybridge1_003873 CN(C)CCCNc1c([N+](=O)[O-])c(C)nn1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I02 compound treatment 1126370.0 17100.0 0.08 1041640.0 -60200.0 -0.36 864360.0 -174524.375 -0.999587035123717 -0.7356 -0.6906 2071321 Maybridge1_003874 COC(=O)c1scc(C)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I03 compound treatment 562880.0 -546000.0 -2.67 572600.0 -529000.0 -3.15 571550.0 -467334.375 -2.6766540909695 -4.9037 -0.9969 2071322 Maybridge1_003875 CCOc1cc(nc(S)n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I04 compound treatment 750890.0 -358000.0 -1.75 698960.0 -403000.0 -2.4 667770.0 -371114.375 -2.12555477020354 -3.6213 -0.9921 2071323 Maybridge1_003876 CCCc1c(cnn1c2ccc(Cl)cc2)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I05 compound treatment 869160.0 -240000.0 -1.17 775390.0 -326000.0 -1.94 691750.0 -347134.375 -1.98820950194364 -2.946 -0.9767 2071324 Maybridge1_003877 O=C1/C(=C/c2cccs2)/Cc3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I06 compound treatment 1058560.0 -50700.0 -0.25 989310.0 -113000.0 -0.67 875640.0 -163244.375 -0.934980920612804 -1.0692 -0.909 2071325 Maybridge1_003878 Cc1csc2ncnc(Sc3ccccc3N)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I07 compound treatment 1246080.0 137000.0 0.67 1112480.0 10600.0 0.06 924760.0 -114124.375 -0.653646492884431 0.045 0.0481 2071326 Maybridge1_003879 CCOC(=O)CCSC1=NC(C(=C(C)N1)C(=O)OCC)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I08 compound treatment 913060.0 -196000.0 -0.96 910290.0 -192000.0 -1.14 749040.0 -289844.375 -1.66008146113422 -2.1696 -0.973 2071327 Maybridge1_003880 COC(=O)c1cscc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I09 compound treatment 1121120.0 11900.0 0.06 1143410.0 41600.0 0.25 1061450.0 22565.625 0.129244446166695 0.2507 0.8804 1035457 Maybridge1_003881 CC(C)CC1NC(=O)NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I10 compound treatment 1296200.0 187000.0 0.91 1057480.0 -44400.0 -0.26 937790.0 -101094.375 -0.579017266636452 0.0407 0.0365 2071328 Maybridge1_003882 COC(=O)c1sccc1Oc2ccc(Cl)cc2[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I11 compound treatment 751520.0 -358000.0 -1.75 639880.0 -462000.0 -2.75 438690.0 -600194.375 -3.43760873404751 -4.5799 -0.9673 2071329 Maybridge1_003883 Fc1ccc(cc1)C(=O)ON=C2C3CC4CC(C3)CC2C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I12 compound treatment 1039740.0 -69500.0 -0.34 993850.0 -108000.0 -0.64 793410.0 -245474.375 -1.40595262240645 -1.3786 -0.8711 1732993 Maybridge1_003884 COC(=O)c1c(C)scc1NC(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I13 compound treatment 1250840.0 142000.0 0.69 1371850.0 270000.0 1.61 1085930.0 47045.625 0.269453460637187 1.4819 0.8378 2071330 Maybridge1_003885 COC(=O)CN(C(=O)c1ccccc1[N+](=O)[O-])C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I14 compound treatment 939310.0 -170000.0 -0.83 935360.0 -166000.0 -0.99 797020.0 -241864.375 -1.38527637476599 -1.8508 -0.977 2071331 Maybridge1_003886 COC(=O)c1sccc1n2c(C)ccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I15 compound treatment 1153550.0 44300.0 0.22 1345160.0 243000.0 1.45 982130.0 -56754.375 -0.325060252681321 0.7726 0.5155 2071332 Maybridge1_003887 CC(=O)CSC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I16 compound treatment 1092170.0 -17100.0 -0.08 1196320.0 94500.0 0.56 1139910.0 101025.625 0.578623501532496 0.6102 0.7526 2071333 Maybridge1_003888 COC(=O)C(Cc1ccc(F)cc1)(Cc2ccc(F)cc2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I17 compound treatment 1332110.0 223000.0 1.09 1164060.0 62200.0 0.37 958560.0 -80324.375 -0.460057249048539 0.5766 0.4655 2071334 Maybridge1_003889 O/C=C(\C#N)/c1nc2ccccc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I18 compound treatment 1272960.0 164000.0 0.8 1243610.0 142000.0 0.84 1075970.0 37085.625 0.212407636122232 1.0711 0.9067 1618849 Maybridge1_003890 OCCNc1ncnc2sccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I19 compound treatment 623310.0 -486000.0 -2.37 640800.0 -461000.0 -2.74 512160.0 -526724.375 -3.01680986586339 -4.6955 -0.9953 2071335 Maybridge1_003891 COC(=O)c1sc(cc1N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I20 compound treatment 997130.0 -112000.0 -0.55 993920.0 -108000.0 -0.64 858100.0 -180784.375 -1.03544113768031 -1.2847 -0.9618 2071336 Maybridge1_003892 CC(=O)c1sc(cc1N)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I21 compound treatment 710900.0 -398000.0 -1.95 756960.0 -345000.0 -2.05 615410.0 -423474.375 -2.42544627337654 -3.7081 -0.9954 2071337 Maybridge1_003893 COC(=O)c1sc(cc1N)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I22 compound treatment 450980.0 -658000.0 -3.22 456240.0 -646000.0 -3.84 399440.0 -639444.375 -3.66241281157883 -6.1879 -0.9973 2071338 Maybridge1_003894 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I23 mock treatment 1188360.0 79100.0 0.39 1056660.0 -45200.0 -0.27 988640.0 -50244.375 -0.287774277019438 -0.0982 -0.1779 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 I24 mock treatment 1102370.0 -6890.0 -0.03 1102830.0 973.0 0.01 1047790.0 8905.625 0.0510068996933732 0.0134 0.2178 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J01 compound treatment 1140000.0 30700.0 0.15 1054830.0 -47000.0 -0.28 922270.0 -116614.375 -0.66790794901317 -0.4603 -0.6225 2071339 Maybridge1_003895 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2ccc(OC(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J02 compound treatment 1154420.0 45200.0 0.22 950970.0 -151000.0 -0.9 886930.0 -151954.375 -0.870317531177679 -0.8931 -0.7036 1724940 Maybridge1_003896 CC(C)(C)c1cc2ncnc(N3CCN(CC3)c4ncnc5cc(sc45)C(C)(C)C)c2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J03 compound treatment 1093440.0 -15800.0 -0.08 830890.0 -271000.0 -1.61 707700.0 -331184.375 -1.89685599782581 -2.0701 -0.8313 2071340 Maybridge1_003897 CCOC(=O)c1c(sc2CCCCc12)n3c(C)ccc3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J04 compound treatment 1254080.0 145000.0 0.71 1016120.0 -85700.0 -0.51 1000810.0 -38074.375 -0.218070694253674 -0.0117 -0.0131 2071341 Maybridge1_003898 NC(=N)NC(=N)NCc1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J05 compound treatment 1058250.0 -51000.0 -0.25 967360.0 -134000.0 -0.8 921560.0 -117324.375 -0.671974468632208 -0.9936 -0.9252 2071342 Maybridge1_003899 CCNC(=S)Nc1c(C)cc(C)cc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J06 compound treatment 656440.0 -453000.0 -2.21 755100.0 -347000.0 -2.06 761390.0 -277494.375 -1.58934692973265 -3.3854 -0.9909 2071343 Maybridge1_003900 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)S(=O)(=O)c4ccc(Cl)cc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J07 compound treatment 1045920.0 -63300.0 -0.31 1044090.0 -57800.0 -0.34 742620.0 -296264.375 -1.6968519624782 -1.3567 -0.7714 2071344 Maybridge1_003901 Cn1nccc1NC(=O)Nc2ccc(OC(F)(F)F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J08 compound treatment 854370.0 -255000.0 -1.25 801760.0 -300000.0 -1.78 781990.0 -256894.375 -1.47136058585633 -2.5988 -0.9893 2071345 Maybridge1_003902 Clc1ccc(Sc2ncnc3ccsc23)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J09 compound treatment 1341070.0 232000.0 1.13 1112210.0 10400.0 0.06 990090.0 -48794.375 -0.279469413008726 0.5281 0.4521 1286388 Maybridge1_003903 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J10 compound treatment 842050.0 -267000.0 -1.31 777810.0 -324000.0 -1.93 802750.0 -236134.375 -1.35245784319263 -2.6471 -0.9833 2071346 Maybridge1_003904 FC(F)(F)c1ccn(n1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J11 compound treatment 1440080.0 331000.0 1.62 1103580.0 1720.0 0.01 994960.0 -43924.375 -0.251576524917578 0.7939 0.4853 1327348 Maybridge1_003905 Cn1nccc1NS(=O)(=O)c2cccc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J12 compound treatment 1026320.0 -82900.0 -0.41 829670.0 -272000.0 -1.62 798160.0 -240724.375 -1.37874703340585 -1.9645 -0.9076 2071347 Maybridge1_003906 CN(C)/N=C(/C(=O)C(F)(F)F)\c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J13 compound treatment 1270520.0 161000.0 0.79 1125970.0 24100.0 0.14 964390.0 -74494.375 -0.426665968233058 0.2913 0.3211 1205526 Maybridge1_003907 Cn1nccc1NS(=O)(=O)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J14 compound treatment 1177400.0 68100.0 0.33 1140530.0 38700.0 0.23 1132540.0 93655.625 0.536411882388398 0.6347 0.9446 2071348 Maybridge1_003908 [O-][N+](=O)c1cccc(c1)C(=O)NC(=S)Nc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J15 compound treatment 586260.0 -523000.0 -2.56 454880.0 -647000.0 -3.85 455270.0 -583614.375 -3.34264690970434 -5.6264 -0.9869 2071349 Maybridge1_003909 CC(=O)c1sc(cc1N)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J16 compound treatment 1402400.0 293000.0 1.43 1144530.0 42700.0 0.25 1127900.0 89015.625 0.509836317554122 1.2678 0.8225 2071350 Maybridge1_003910 OCCNNC(=S)NC1CC2CC1C=C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J17 compound treatment 1407530.0 298000.0 1.46 1206940.0 105000.0 0.62 918850.0 -120034.375 -0.687495973093606 0.8052 0.4659 1513059 Maybridge1_003911 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Cl)cc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J18 compound treatment 590750.0 -519000.0 -2.53 614670.0 -487000.0 -2.9 526250.0 -512634.375 -2.93610949764897 -4.8304 -0.9979 2071351 Maybridge1_003912 CNc1nc(cs1)c2ccc(Cl)s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J19 compound treatment 981050.0 -128000.0 -0.63 898100.0 -204000.0 -1.21 841310.0 -197574.375 -1.13160573543192 -1.7145 -0.9674 1212957 Maybridge1_003913 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J20 compound treatment 1107680.0 -1580.0 -0.01 1068160.0 -33700.0 -0.2 1049120.0 10235.625 0.0586244646135429 -0.0863 -0.413 1715187 Maybridge1_003914 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(cc2)N3CCN(C)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J21 compound treatment 874160.0 -235000.0 -1.15 995560.0 -106000.0 -0.63 855150.0 -183734.375 -1.05233724032279 -1.6357 -0.9729 2071352 Maybridge1_003915 Cn1ncc2c(N/N=C/c3ccc(Cl)cc3)ncnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J22 compound treatment 1188450.0 79200.0 0.39 1027390.0 -74500.0 -0.44 991200.0 -47684.375 -0.273111896421216 -0.19 -0.293 1397071 Maybridge1_003916 OC(=O)COCC(=O)N1CCN(CC1)C(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J23 mock treatment 1377360.0 268000.0 1.31 1007680.0 -94200.0 -0.56 1142630.0 103745.625 0.594202280918106 0.776 0.5027 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 J24 mock treatment 1231360.0 122000.0 0.6 1086450.0 -15400.0 -0.09 1068560.0 29675.625 0.169966917281287 0.3897 0.6214 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K01 compound treatment 843520.0 -266000.0 -1.3 723370.0 -378000.0 -2.25 750670.0 -288214.375 -1.6507456484877 -3.0021 -0.9752 2071353 Maybridge1_003917 CSC(=NC(=O)c1c(Cl)cccc1Cl)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K02 compound treatment 1155420.0 46200.0 0.23 1008740.0 -93100.0 -0.55 927040.0 -111844.375 -0.64058781016414 -0.5593 -0.6383 2071354 Maybridge1_003918 Cc1csc(C(=O)O)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K03 compound treatment 1053710.0 -55500.0 -0.27 958920.0 -143000.0 -0.85 929520.0 -109364.375 -0.626383628959613 -1.0091 -0.9256 2071355 Maybridge1_003919 COc1ccc(NCCC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K04 compound treatment 1205120.0 95900.0 0.47 912960.0 -189000.0 -1.12 846300.0 -192584.375 -1.10302554825023 -1.0149 -0.6179 2071356 Maybridge1_003920 CCOC(=O)c1cnn(c1C(F)(F)F)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K05 compound treatment 1330500.0 221000.0 1.08 984870.0 -117000.0 -0.7 849190.0 -189694.375 -1.08647309515302 -0.4048 -0.2405 2071357 Maybridge1_003921 COc1nc-2c(Cc3ccccc32)c(c4cccs4)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K06 compound treatment 1012420.0 -96800.0 -0.47 783280.0 -319000.0 -1.89 680440.0 -358444.375 -2.05298744122719 -2.5522 -0.9008 2071358 Maybridge1_003922 Nc1cc(nc(N)n1)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K07 compound treatment 933020.0 -176000.0 -0.86 943310.0 -159000.0 -0.94 806920.0 -231964.375 -1.32857419979631 -1.8085 -0.9815 1317778 Maybridge1_003923 CCOC(=O)C1=C(C)NC(=S)N(C1c2cccs2)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K08 compound treatment 1380210.0 271000.0 1.32 1032480.0 -69400.0 -0.41 930830.0 -108054.375 -0.618880613887867 0.1688 0.1112 2071327 Maybridge1_003924 COC(=O)c1cscc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K09 compound treatment 815330.0 -294000.0 -1.44 640840.0 -461000.0 -2.74 605150.0 -433734.375 -2.48421034561785 -3.8462 -0.9692 2071359 Maybridge1_003925 N#C/C(=C\c1cccs1)/c2nc3ccccc3[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K10 compound treatment 1376050.0 267000.0 1.3 1112840.0 11000.0 0.07 956640.0 -82244.375 -0.471054034497205 0.5183 0.3736 2071360 Maybridge1_003926 CCOC(=O)c1cnn(c1C(F)(F)F)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K11 compound treatment 49920.0 -1060000.0 -5.18 46250.0 -1060000.0 -6.28 42310.0 -996574.375 -5.70787217995493 -9.9078 -0.9969 2071361 Maybridge1_003927 FC(F)(F)c1cccc(c1)C(=O)ON=C2C3CC4CC(C3)CC2C4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K12 compound treatment 1208270.0 99000.0 0.48 1026960.0 -74900.0 -0.45 987530.0 -51354.375 -0.294131793606948 -0.1477 -0.205 2071362 Maybridge1_003928 CCOC(=O)c1cnn(c1C(F)(F)F)c2ccc(N)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K13 compound treatment 1300580.0 191000.0 0.93 1095600.0 -6260.0 -0.04 1107010.0 68125.625 0.390189000875667 0.7435 0.7335 2071363 Maybridge1_003929 CCOC(=O)CN(C(=O)c1ccccc1[N+](=O)[O-])C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K14 compound treatment 1143080.0 33800.0 0.17 1149790.0 47900.0 0.29 966900.0 -71984.375 -0.412289962255896 0.0219 0.0416 2071364 Maybridge1_003930 COC(=O)c1scc(Br)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K15 compound treatment 1056590.0 -52700.0 -0.26 979100.0 -123000.0 -0.73 935950.0 -102934.375 -0.589555852691424 -0.9104 -0.9357 1075012 Maybridge1_003931 Cc1csc(N)c1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K16 compound treatment 913030.0 -196000.0 -0.96 895630.0 -206000.0 -1.23 845700.0 -193184.375 -1.10646204370294 -1.9004 -0.9951 1734344 Maybridge1_003932 OC(=O)c1ccccc1C(=O)Nc2sc3CCCCc3c2C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K17 compound treatment 1225850.0 117000.0 0.57 980050.0 -122000.0 -0.72 938930.0 -99954.375 -0.572487925276307 -0.4198 -0.387 2071365 Maybridge1_003933 NC1=C(C(C(=C2Sc3ccccc3N21)C#N)c4ccc(C#N)cc4)c5nc6ccccc6s5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K18 compound treatment 1219480.0 110000.0 0.54 1109280.0 7420.0 0.04 928320.0 -110564.375 -0.633256619865029 -0.0292 -0.0351 1160325 Maybridge1_003934 Cc1ccc(C)n1c2sccc2C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K19 compound treatment 923790.0 -185000.0 -0.91 734720.0 -367000.0 -2.18 739840.0 -299044.375 -1.71277439140908 -2.7725 -0.9498 1634867 Maybridge1_003935 COC(=O)c1sc(cc1N)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K20 compound treatment 802480.0 -307000.0 -1.5 715380.0 -386000.0 -2.3 598900.0 -439984.375 -2.52000717325022 -3.6472 -0.979 2071366 Maybridge1_003936 COC(=O)c1sc(cc1N)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K21 compound treatment 779570.0 -330000.0 -1.61 720260.0 -382000.0 -2.27 663330.0 -375554.375 -2.15098483655358 -3.482 -0.99 1701180 Maybridge1_003937 COc1ccc(cc1)c2cc(N)c(s2)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K22 compound treatment 1229920.0 121000.0 0.59 1033060.0 -68800.0 -0.41 975410.0 -63474.375 -0.363549001751652 -0.1057 -0.1314 2071367 Maybridge1_003938 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)NS(=O)(=O)c3ccc(C)cc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K23 mock treatment 1139270.0 30000.0 0.15 1106680.0 4820.0 0.03 1108390.0 69505.625 0.398092940416895 0.3311 0.7786 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 K24 mock treatment 1333990.0 225000.0 1.1 1158510.0 56700.0 0.34 1123680.0 84795.625 0.485666299536741 1.1088 0.8892 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L01 compound treatment 1203770.0 94500.0 0.46 1020440.0 -81400.0 -0.48 962360.0 -76524.375 -0.438292777848054 -0.266 -0.3325 1674796 Maybridge1_003939 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2cccc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L02 compound treatment 1374990.0 266000.0 1.3 943680.0 -158000.0 -0.94 987410.0 -51474.375 -0.294819092697489 0.0363 0.0223 2071368 Maybridge1_003940 COc1ccc(/C=N/NC(=O)c2cnn(c2C(F)(F)F)c3ccc(cc3)[N+](=O)[O-])cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L03 compound treatment 981840.0 -127000.0 -0.62 878890.0 -223000.0 -1.33 725690.0 -313194.375 -1.79381840916878 -2.1606 -0.9329 1370879 Maybridge1_003941 COC(=O)c1cc(OC)c(OC)cc1n2c(C)ccc2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L04 compound treatment 1054240.0 -55000.0 -0.27 919010.0 -183000.0 -1.09 898170.0 -140714.375 -0.805940516363613 -1.2483 -0.9046 2071369 Maybridge1_003942 Cc1ccc(/C=N/c2ccc(C)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L05 compound treatment 1064680.0 -44600.0 -0.22 985280.0 -117000.0 -0.69 874170.0 -164714.375 -0.943400334471939 -1.0707 -0.8991 2071370 Maybridge1_003943 Cc1cc(C)c(NC(=S)NCc2ccco2)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L06 compound treatment 1350050.0 241000.0 1.18 953660.0 -148000.0 -0.88 930240.0 -108644.375 -0.622259834416363 -0.1888 -0.1183 2071371 Maybridge1_003944 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)c4cccs4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L07 compound treatment 1428540.0 319000.0 1.56 1061640.0 -40200.0 -0.24 967620.0 -71264.375 -0.408166167712646 0.5269 0.3232 2071372 Maybridge1_003945 Cn1nccc1NC(=O)Nc2cccc(c2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L08 compound treatment 1452640.0 343000.0 1.68 1105180.0 3320.0 0.02 936700.0 -102184.375 -0.585260233375539 0.6421 0.3614 2071373 Maybridge1_003946 Fc1cc(Br)c(F)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L09 compound treatment 1308660.0 199000.0 0.97 1050340.0 -51500.0 -0.31 1002130.0 -36754.375 -0.210510404257716 0.2641 0.2532 1398582 Maybridge1_003947 Cn1nccc1NS(=O)(=O)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L10 compound treatment 1094780.0 -14500.0 -0.07 858560.0 -243000.0 -1.45 719380.0 -319504.375 -1.82995888634643 -1.9327 -0.8281 1537015 Maybridge1_003948 C1CN(CCN1)c2nc(ns2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L11 compound treatment 928920.0 -180000.0 -0.88 735680.0 -366000.0 -2.18 639280.0 -399604.375 -2.28873102928296 -3.0873 -0.9413 1723996 Maybridge1_003949 CC(C)Nc1ncnc2sc3CCCCc3c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L12 compound treatment 780380.0 -329000.0 -1.61 734500.0 -367000.0 -2.18 646620.0 -392264.375 -2.2466912349115 -3.4861 -0.9899 2071374 Maybridge1_003950 Cc1ccc(cc1)C(=O)C(O)(O)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L13 compound treatment 1305200.0 196000.0 0.96 1311760.0 210000.0 1.25 1049550.0 10665.625 0.0610872863546504 1.3086 0.8313 1530996 Maybridge1_003951 COc1ccc(cc1)S(=O)(=O)Nc2ccnn2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L14 compound treatment 950760.0 -158000.0 -0.77 883270.0 -219000.0 -1.3 913180.0 -125704.375 -0.719970855121698 -1.6132 -0.9628 2071375 Maybridge1_003952 [O-][N+](=O)c1cccc(c1)C(=O)NC(=S)Nc2cccc(Cl)c2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L15 compound treatment 1315530.0 206000.0 1.01 1090290.0 -11600.0 -0.07 944960.0 -93924.375 -0.53795114597659 0.2316 0.2023 1661227 Maybridge1_003953 CC(C)(C)c1ccc(cc1)c2cc(N)c(s2)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L16 compound treatment 698240.0 -411000.0 -2.01 646240.0 -456000.0 -2.71 560750.0 -478134.375 -2.73851100911825 -4.3047 -0.9909 1680767 Maybridge1_003954 CC(C)c1ccc(NC(=S)NC2CC3CC2C4C=CCC34)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L17 compound treatment 1486180.0 377000.0 1.84 1360250.0 258000.0 1.54 1005970.0 -32914.375 -0.188516833360384 1.8415 0.7654 1594290 Maybridge1_003955 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L18 compound treatment 1406040.0 297000.0 1.45 1348480.0 247000.0 1.47 1085080.0 46195.625 0.264585092079184 1.8367 0.8833 2071376 Maybridge1_003956 CC(C)c1ccc(NC(=O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L19 compound treatment 1302650.0 193000.0 0.94 1190960.0 89100.0 0.53 938650.0 -100234.375 -0.574091623154237 0.52 0.4241 1728790 Maybridge1_003957 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L20 compound treatment 1209410.0 100000.0 0.49 1134840.0 33000.0 0.2 1104360.0 65475.625 0.375011145959539 0.6123 0.9464 2071377 Maybridge1_003958 Cc1onc(c1C(=O)NCc2nc(no2)c3ccc(cc3)C(F)(F)F)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L21 compound treatment 606460.0 -503000.0 -2.46 566320.0 -536000.0 -3.18 463520.0 -575364.375 -3.2953950972296 -5.1595 -0.9923 2071378 Maybridge1_003959 Cc1ccc(cc1)C(=O)NNc2ncnc3cc(sc23)c4ccc(cc4)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L22 compound treatment 886640.0 -223000.0 -1.09 820160.0 -282000.0 -1.68 792540.0 -246344.375 -1.41093554081288 -2.4097 -0.9854 1122099 Maybridge1_003960 OCCN1CCN(CN2C(=O)C3(OCCO3)c4ccccc24)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L23 mock treatment 1098610.0 -10600.0 -0.05 1081220.0 -20600.0 -0.12 1062560.0 23675.625 0.135601962754205 -0.0226 -0.1188 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 L24 mock treatment 1397600.0 288000.0 1.41 1204700.0 103000.0 0.61 986560.0 -52324.375 -0.299687461255492 0.9934 0.6349 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M01 compound treatment 1225120.0 116000.0 0.57 1081960.0 -19900.0 -0.12 1111720.0 72835.625 0.417165490179425 0.4994 0.7003 2071379 Maybridge1_003961 CS/C(=N/C(=O)c1c(Cl)cccc1Cl)/NCCc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M02 compound treatment 1259380.0 150000.0 0.73 1062960.0 -38900.0 -0.23 955230.0 -83654.375 -0.479129798811069 0.0133 0.0147 2071380 Maybridge1_003962 Cc1csc(C(=O)NN)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M03 compound treatment 1137810.0 28600.0 0.14 838090.0 -264000.0 -1.57 912200.0 -126684.375 -0.725583797694454 -1.2439 -0.7175 1636017 Maybridge1_003963 COC(=O)CCNc1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M04 compound treatment 1182560.0 73300.0 0.36 1003680.0 -98200.0 -0.58 913920.0 -124964.375 -0.715732510730025 -0.5435 -0.5486 2071381 Maybridge1_003964 CCCc1c(cnn1c2ccc(Cl)cc2)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M05 compound treatment 1302040.0 193000.0 0.94 1049440.0 -52400.0 -0.31 858760.0 -180124.375 -1.03166099268233 -0.2318 -0.1619 2071382 Maybridge1_003965 CC(C)(C)c1cc(/C=C/2\Cc3ccccc3C2=O)cc(c1O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M06 compound treatment 1293360.0 184000.0 0.9 1083590.0 -18300.0 -0.11 902080.0 -136804.375 -0.783546020996798 0.0042 0.0035 2071383 Maybridge1_003966 CCOC(=O)c1c[nH]c(=O)nc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M07 compound treatment 80820.0 -1030000.0 -5.02 59720.0 -1040000.0 -6.2 56970.0 -981914.375 -5.62390714106042 -9.7259 -0.9964 2071384 Maybridge1_003967 NC1=C(C#N)C(C(C#N)C#N)c2cc(Cl)ccc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M08 compound treatment 736530.0 -373000.0 -1.82 575910.0 -526000.0 -3.13 587760.0 -451124.375 -2.58381143882217 -4.3489 -0.978 2071385 Maybridge1_003968 CC(=O)c1sc(cc1N)c2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M09 compound treatment 839460.0 -270000.0 -1.32 663060.0 -439000.0 -2.61 575680.0 -463204.375 -2.65299954727003 -3.7993 -0.9624 2071386 Maybridge1_003969 COC(=O)C(C#N)C1C(=C(N)Oc2ccccc12)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M10 compound treatment 1315470.0 206000.0 1.01 1081010.0 -20800.0 -0.12 1014940.0 -23944.375 -0.137141226342397 0.4309 0.4207 2071387 Maybridge1_003970 OC(=O)c1cnn(c1C(F)(F)F)c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M11 compound treatment 1018110.0 -91100.0 -0.45 852480.0 -249000.0 -1.48 693700.0 -345184.375 -1.97704089172234 -2.2547 -0.8979 2071388 Maybridge1_003971 Cc1onc(c1C(=O)ON=C2C3CC4CC(C3)CC2C4)c5ccccc5Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M12 compound treatment 1345040.0 236000.0 1.15 1099630.0 -2230.0 -0.01 870460.0 -168424.375 -0.964649331354517 0.1005 0.0669 2071389 Maybridge1_003972 CCCc1c(cnn1c2ccc(cc2)[N+](=O)[O-])C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M13 compound treatment 1129520.0 20300.0 0.1 1037370.0 -64500.0 -0.38 908260.0 -130624.375 -0.748150117833905 -0.5962 -0.7043 1130128 Maybridge1_003973 Clc1ccc(c(Cl)c1)c2cc3C(=O)c4ccccc4-c3nn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M14 compound treatment 1070670.0 -38600.0 -0.19 887520.0 -214000.0 -1.27 822840.0 -216044.375 -1.23739252045112 -1.5591 -0.8728 2071390 Maybridge1_003974 CC(C)(C)c1cc(N)c(C#N)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M15 compound treatment 1009760.0 -99500.0 -0.49 809700.0 -292000.0 -1.74 788670.0 -250214.375 -1.43310093648285 -2.1111 -0.9163 1355900 Maybridge1_003975 COC(=O)c1sccc1NC(=O)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M16 compound treatment 1476960.0 368000.0 1.8 1140680.0 38800.0 0.23 940030.0 -98854.375 -0.566187683613009 0.8436 0.4445 3177423 Maybridge1_003976 Cc1ccc(cc1)S(=O)(=O)O.N[C@@H](CC(=O)OCc1ccccc1)C(=O)OCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M17 compound treatment 739770.0 -369000.0 -1.81 649890.0 -452000.0 -2.69 632380.0 -406504.375 -2.32825072698911 -3.9382 -0.9875 2071392 Maybridge1_003977 COC(=O)c1sc(cc1N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M18 compound treatment 1247040.0 138000.0 0.67 1091110.0 -10700.0 -0.06 962400.0 -76484.375 -0.438063678151207 0.0989 0.1227 2071393 Maybridge1_003978 C/C(=N\O)/C(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M19 compound treatment 1262330.0 153000.0 0.75 1020230.0 -81600.0 -0.49 898000.0 -140884.375 -0.806914190075214 -0.3143 -0.2614 2071394 Maybridge1_003979 CCOC(=O)c1c[nH]nc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M20 compound treatment 1351240.0 242000.0 1.18 1080220.0 -21600.0 -0.13 1045600.0 6715.625 0.0384636912909885 0.6305 0.5299 1358367 Maybridge1_003980 NS(=O)(=O)c1cccc(C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M21 compound treatment 1409190.0 300000.0 1.47 1097620.0 -4240.0 -0.03 941330.0 -97554.375 -0.558741943465474 0.5089 0.3245 2071395 Maybridge1_003981 CNNC(=O)Cc1ccc(OC)c(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M22 compound treatment 1167110.0 57900.0 0.28 1211890.0 110000.0 0.65 1068010.0 29125.625 0.166816796449638 0.6373 0.8706 2071396 Maybridge1_003982 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M23 mock treatment 1081570.0 -27700.0 -0.14 1081630.0 -20200.0 -0.12 1035040.0 -3844.375 -0.0220186286766748 -0.1603 -0.8788 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 M24 mock treatment 1009870.0 -99400.0 -0.49 1003040.0 -98800.0 -0.59 991480.0 -47404.375 -0.271508198543286 -0.7764 -0.9594 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N01 compound treatment 1179040.0 69800.0 0.34 871570.0 -230000.0 -1.37 957860.0 -81024.375 -0.464066493743365 -0.8617 -0.5801 2071397 Maybridge1_003983 Cn1nccc1NC(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N02 compound treatment 1421320.0 312000.0 1.52 1055010.0 -46800.0 -0.28 859430.0 -179454.375 -1.02782357276014 0.126 0.0678 2071398 Maybridge1_003984 [O-][N+](=O)c1ccc(cc1)n2ncc(C(=O)N/N=C/c3ccc(C#N)cc3)c2C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N03 compound treatment 907280.0 -202000.0 -0.99 709760.0 -392000.0 -2.33 688900.0 -349984.375 -2.004532855344 -3.0732 -0.9517 1532326 Maybridge1_003985 Cc1ccc(C)n1c2sc3CCCCc3c2C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N04 compound treatment 225200.0 -884000.0 -4.32 219770.0 -882000.0 -5.25 231480.0 -807404.375 -4.62440243864026 -8.1921 -0.9967 2071399 Maybridge1_003986 CNC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N05 compound treatment 1332180.0 223000.0 1.09 1082410.0 -19400.0 -0.12 957630.0 -81254.375 -0.465383817000237 0.2934 0.2465 2071400 Maybridge1_003987 NC(=S)NCc1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N06 compound treatment 1205160.0 95900.0 0.47 1056230.0 -45600.0 -0.27 895910.0 -142974.375 -0.81888464923548 -0.3589 -0.3656 2071401 Maybridge1_003988 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)c4ccco4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N07 compound treatment 1425500.0 316000.0 1.55 1109600.0 7740.0 0.05 1029770.0 -9114.375 -0.0522025137362946 0.8885 0.5745 1669792 Maybridge1_003989 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N08 compound treatment 1416160.0 307000.0 1.5 1038820.0 -63000.0 -0.37 938140.0 -100744.375 -0.577012644289039 0.3162 0.1916 1239102 Maybridge1_003990 OC(=O)C(Cc1ccccc1)NC(=O)c2ccc(cc2)C(=O)NC(Cc3ccccc3)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N09 compound treatment 1445120.0 336000.0 1.64 1055380.0 -46500.0 -0.28 916550.0 -122334.375 -0.70066920566232 0.3833 0.2123 1681140 Maybridge1_003991 Cc1c(Cl)cccc1S(=O)(=O)Nc2ccnn2C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N10 compound treatment 1382120.0 273000.0 1.33 1092330.0 -9530.0 -0.06 981810.0 -57074.375 -0.326893050256099 0.5483 0.3991 1531989 Maybridge1_003992 OC(=O)CSCC(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N11 compound treatment 1375710.0 266000.0 1.3 1003450.0 -98400.0 -0.59 851240.0 -187644.375 -1.0747317356896 -0.2067 -0.1157 1552824 Maybridge1_003993 COC(=O)c1ccccc1NC(=O)c2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N12 compound treatment 1218290.0 109000.0 0.53 1003440.0 -98400.0 -0.59 880080.0 -158804.375 -0.909550854262764 -0.5555 -0.4607 1634253 Maybridge1_003994 CCOC(=O)c1ccc(NC(=S)NCCc2ccc(OC)c(OC)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N13 compound treatment 1429200.0 320000.0 1.56 1151310.0 49500.0 0.29 1046520.0 7635.625 0.0437329843184743 1.0975 0.6898 1325092 Maybridge1_003995 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N14 compound treatment 997520.0 -112000.0 -0.55 938190.0 -164000.0 -0.97 864270.0 -174614.375 -1.00010250944162 -1.4545 -0.9707 1305504 Maybridge1_003996 COc1ccc(CCNC(=S)NC2CC3CC2C=C3)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N15 compound treatment 1387060.0 278000.0 1.36 1250640.0 149000.0 0.88 1045290.0 6405.625 0.0366881686404226 1.3156 0.8118 1295871 Maybridge1_003997 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Nc3cc(C)cc(C)c3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N16 compound treatment 1407520.0 298000.0 1.46 1192080.0 90200.0 0.54 1039560.0 675.625 0.00386963706705989 1.1533 0.7427 2071402 Maybridge1_003998 Clc1ccc(cc1)c2nc(cs2)c3ccc(Br)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N17 compound treatment 1374960.0 266000.0 1.3 1118020.0 16200.0 0.1 1015360.0 -23524.375 -0.134735679525502 0.7272 0.5557 1660249 Maybridge1_003999 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(F)cc3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N18 compound treatment 1314120.0 205000.0 1.0 1093130.0 -8730.0 -0.05 949700.0 -89184.375 -0.510802831900196 0.253 0.2249 2071403 Maybridge1_004000 FC(F)(F)Oc1ccc(NC(=O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N19 compound treatment 684390.0 -425000.0 -2.08 662720.0 -439000.0 -2.61 660200.0 -378684.375 -2.16891188783187 -3.9584 -0.9948 331 Maybridge1_004001 COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N20 compound treatment 1319080.0 210000.0 1.03 1177810.0 76000.0 0.45 1096570.0 57685.625 0.330393979998545 1.0434 0.8934 1381468 Maybridge1_004002 CC(C)(CC(=O)O)CC(=O)Nc1ccc2OCCCOc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N21 compound treatment 1110120.0 864.0 0.0 1001520.0 -100000.0 -0.6 855110.0 -183774.375 -1.05256634001963 -0.9497 -0.785 1577705 Maybridge1_004003 CC(C)(C)c1cc2ncnc(N3CCOCC3)c2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N22 compound treatment 1358690.0 249000.0 1.22 1207520.0 106000.0 0.63 1021340.0 -17544.375 -0.100485274846844 1.0084 0.7335 2071404 Maybridge1_004004 COc1ccc(cc1)c2ccnc(SCC(=O)Nc3ccccc3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N23 mock treatment 1290510.0 181000.0 0.89 1126720.0 24900.0 0.15 1238010.0 199125.625 1.14049050805028 1.2551 0.8647 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 N24 mock treatment 1016250.0 -93000.0 -0.45 1007640.0 -94200.0 -0.56 1070670.0 31785.625 0.182051926289977 -0.4807 -0.6461 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O01 compound treatment 1099770.0 -9490.0 -0.05 843610.0 -258000.0 -1.54 931940.0 -106944.375 -0.612523097300357 -1.267 -0.766 2071405 Maybridge1_004005 CSC(=C(C#N)c1ccccc1)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O02 compound treatment 1136960.0 27700.0 0.14 1107680.0 5820.0 0.03 919300.0 -119584.375 -0.684918601504075 -0.2973 -0.4253 2071406 Maybridge1_004006 OC(=O)c1sccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O03 compound treatment 1081200.0 -28100.0 -0.14 924240.0 -178000.0 -1.06 820880.0 -218004.375 -1.24861840559663 -1.4098 -0.859 2071407 Maybridge1_004007 C/C(=N\O)/C=C/c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O04 compound treatment 1246830.0 138000.0 0.67 992480.0 -109000.0 -0.65 947520.0 -91364.375 -0.523288765378369 -0.2896 -0.2702 2071408 Maybridge1_004008 OC(=O)c1cnn(c1C(F)(F)F)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O05 compound treatment 1102010.0 -7250.0 -0.04 964480.0 -137000.0 -0.82 944640.0 -94244.375 -0.539783943551368 -0.8037 -0.8203 2071409 Maybridge1_004009 [O-][N+](=O)c1ccc(OC(=O)OC2(CC3CC4CC(C3)C2)C4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O06 compound treatment 1290090.0 181000.0 0.88 1117060.0 15200.0 0.09 1006180.0 -32704.375 -0.187314059951936 0.4542 0.5003 2071410 Maybridge1_004010 CC(C)(C)c1cc(N)nc(N)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O07 compound treatment 60030.0 -1050000.0 -5.13 49040.0 -1050000.0 -6.26 45210.0 -993674.375 -5.6912624519335 -9.8601 -0.9967 2071411 Maybridge1_004011 NC1=C(C#N)C(C(C#N)C#N)c2cc(Br)ccc2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O08 compound treatment 1064060.0 -45200.0 -0.22 975740.0 -126000.0 -0.75 997880.0 -41004.375 -0.234852247047732 -0.6961 -0.8527 2071412 Maybridge1_004012 COC(=O)c1scc(Br)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O09 compound treatment 847880.0 -261000.0 -1.28 801860.0 -300000.0 -1.78 712100.0 -326784.375 -1.87165503117262 -2.8479 -0.9875 2071413 Maybridge1_004013 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccccc12)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O10 compound treatment 581920.0 -527000.0 -2.58 415230.0 -687000.0 -4.08 437730.0 -601154.375 -3.44310712677184 -5.8328 -0.9836 1117875 Maybridge1_004014 COC(=O)c1sc(cc1N)c2ccc(CC(C)C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O11 compound treatment 1354730.0 245000.0 1.2 1078470.0 -23400.0 -0.14 920480.0 -118404.375 -0.678160160447082 0.2206 0.1593 2071414 Maybridge1_004015 CC/1=C2CCCC2CC\C1=N/NC(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O12 compound treatment 1412050.0 303000.0 1.48 1157040.0 55200.0 0.33 1120180.0 81295.625 0.46562007606261 1.3124 0.8279 2071415 Maybridge1_004016 CC(=O)c1sccc1NC(=O)c2ccccc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O13 compound treatment 1268380.0 159000.0 0.78 1030290.0 -71600.0 -0.43 1032480.0 -6404.375 -0.0366810092748961 0.182 0.2051 2071416 Maybridge1_004017 COC(=O)c1sccc1NC(=S)Nc2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O14 compound treatment 1330500.0 221000.0 1.08 1135810.0 34000.0 0.2 979460.0 -59424.375 -0.340352657445872 0.5442 0.4727 2071417 Maybridge1_004018 Clc1ccc(Cc2nn[nH]n2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O15 compound treatment 1225410.0 116000.0 0.57 986350.0 -116000.0 -0.69 930970.0 -107914.375 -0.618078764948902 -0.4258 -0.3926 1415121 Maybridge1_004019 COC(=O)c1sccc1NC(=O)c2c(F)cccc2F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O16 compound treatment 1404410.0 295000.0 1.44 1184420.0 82600.0 0.49 1055120.0 16235.625 0.0929894191406243 1.1697 0.7664 2071418 Maybridge1_004020 COC(=O)c1sccc1NC(=S)Nc2ccsc2C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O17 compound treatment 1348320.0 239000.0 1.17 1011150.0 -90700.0 -0.54 939650.0 -99234.375 -0.568364130733057 0.0348 0.0247 2071419 Maybridge1_004021 NNC(=O)c1sccc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O18 compound treatment 1320350.0 211000.0 1.03 1167630.0 65800.0 0.39 1045950.0 7065.625 0.0404683136384016 0.8446 0.7652 2071420 Maybridge1_004022 [O-][N+](=O)c1ccc(cc1)c2nn[nH]n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O19 compound treatment 964040.0 -145000.0 -0.71 833860.0 -268000.0 -1.59 784340.0 -254544.375 -1.45790097866656 -2.1715 -0.9551 2071421 Maybridge1_004023 FC(F)(F)c1cc(NC(=O)N/C=C/c2ccco2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O20 compound treatment 1280320.0 171000.0 0.84 1043840.0 -58000.0 -0.35 943000.0 -95884.375 -0.549177031122103 -0.0337 -0.0319 2071422 Maybridge1_004024 Cc1c(sc2cc(sc12)C(C)(C)C)C(=O)O/N=C/c3ccc(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O21 compound treatment 866150.0 -243000.0 -1.19 767060.0 -335000.0 -1.99 752720.0 -286164.375 -1.63900428902428 -2.7815 -0.9797 2071423 Maybridge1_004025 Nc1cc(nc(N)n1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O22 compound treatment 440230.0 -669000.0 -3.27 393810.0 -708000.0 -4.21 398340.0 -640544.375 -3.66871305324213 -6.4362 -0.9947 1637926 Maybridge1_004026 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(OC)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O23 mock treatment 1284960.0 176000.0 0.86 1115930.0 14100.0 0.08 1210670.0 171785.625 0.983900865255209 1.112 0.8499 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 O24 mock treatment 1144360.0 35100.0 0.17 1050110.0 -51700.0 -0.31 972640.0 -66244.375 -0.379414155758321 -0.2977 -0.575 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P01 compound treatment 872000.0 -237000.0 -1.16 780160.0 -322000.0 -1.91 805340.0 -233544.375 -1.33762363782177 -2.546 -0.9769 2071424 Maybridge1_004027 CCOC(=O)CN(C)S(=O)(=O)c1ccsc1C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P02 compound treatment 1130930.0 21700.0 0.11 951550.0 -150000.0 -0.89 917090.0 -121794.375 -0.697576359754883 -0.8576 -0.7532 2071425 Maybridge1_004028 Cc1nc(Cc2ccc(cc2)[N+](=O)[O-])no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P03 compound treatment 1094730.0 -14500.0 -0.07 891950.0 -210000.0 -1.25 899890.0 -138994.375 -0.796089229399183 -1.2213 -0.824 1678568 Maybridge1_004029 COC(=O)CSc1ncnc2cc(OC)c(OC)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P04 compound treatment 1172320.0 63100.0 0.31 926800.0 -175000.0 -1.04 799250.0 -239634.375 -1.37250406666676 -1.2155 -0.6946 2071426 Maybridge1_004030 Nc1cc(O)nc(SCc2c(Cl)cccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P05 compound treatment 1148240.0 39000.0 0.19 1042400.0 -59500.0 -0.35 907520.0 -131364.375 -0.752388462225578 -0.5286 -0.6197 2071427 Maybridge1_004031 Nc1ncnc(n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P06 compound treatment 1127950.0 18700.0 0.09 1022180.0 -79700.0 -0.47 1023480.0 -15404.375 -0.0882284410655182 -0.2718 -0.554 2071428 Maybridge1_004032 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)c4cc(Cl)cc(Cl)c4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P07 compound treatment 1243040.0 134000.0 0.65 1071360.0 -30500.0 -0.18 909600.0 -129284.375 -0.740475277989523 -0.1548 -0.1542 1607107 Maybridge1_004033 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccnn3C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P08 compound treatment 1231380.0 122000.0 0.6 1134780.0 32900.0 0.2 922840.0 -116044.375 -0.664643278333097 0.0738 0.0807 2071429 Maybridge1_004034 Fc1cc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)c(F)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P09 compound treatment 1294350.0 185000.0 0.9 1182820.0 81000.0 0.48 990810.0 -48074.375 -0.275345618465476 0.6411 0.6043 2071430 Maybridge1_004035 Cn1nccc1NC(=O)C2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P10 compound treatment 1122320.0 13100.0 0.06 1050690.0 -51200.0 -0.3 944120.0 -94764.375 -0.542762239610382 -0.4522 -0.7229 2071431 Maybridge1_004036 COC(=O)c1ccccc1CSc2nccc(n2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P11 compound treatment 1079610.0 -29600.0 -0.14 837770.0 -264000.0 -1.57 864060.0 -174824.375 -1.00130528285007 -1.5684 -0.8396 1214297 Maybridge1_004037 COC(=O)c1ccccc1NC(=O)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P12 compound treatment 880690.0 -229000.0 -1.12 930560.0 -171000.0 -1.02 886000.0 -152884.375 -0.875644099129377 -1.7384 -0.9952 1335445 Maybridge1_004038 COc1ccc(CCNC(=S)Nc2ccc(C)cc2C)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P13 compound treatment 1116320.0 7060.0 0.03 1042560.0 -59300.0 -0.35 1044810.0 5925.625 0.0339389722782561 -0.1641 -0.4609 1232563 Maybridge1_004039 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2ccccc2Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P14 compound treatment 1173010.0 63800.0 0.31 1073180.0 -28700.0 -0.17 999110.0 -39774.375 -0.227807431369681 -0.0501 -0.1188 1130038 Maybridge1_004040 S=C(NC1CC2CC1C=C2)NC3CCCCCCCCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P15 compound treatment 1208030.0 98800.0 0.48 1075200.0 -26700.0 -0.16 987640.0 -51244.375 -0.293501769440618 0.0177 0.0301 2071432 Maybridge1_004041 Cn1ncc(Br)c1NC(=O)Nc2ccc(F)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P16 compound treatment 1265860.0 157000.0 0.77 1085120.0 -16700.0 -0.1 1010740.0 -28144.375 -0.161196694511354 0.2912 0.3695 2071433 Maybridge1_004042 [O-][N+](=O)c1ccc(cc1)c2csc(n2)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P17 compound treatment 1286400.0 177000.0 0.87 1003150.0 -98700.0 -0.59 1052480.0 13595.625 0.0778688391487085 0.2058 0.1962 1213717 Maybridge1_004043 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3cccs3)cc2)no1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P18 compound treatment 1211550.0 102000.0 0.5 1110810.0 8950.0 0.05 1016080.0 -22804.375 -0.130611884982252 0.2439 0.4696 2071434 Maybridge1_004044 [O-][N+](=O)c1ccc(nc1)N2CCN(CC(=O)Nc3ccc4OCOc4c3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P19 compound treatment 945440.0 -164000.0 -0.8 818840.0 -283000.0 -1.68 814250.0 -224634.375 -1.28659168034906 -2.1766 -0.9611 1179493 Maybridge1_004045 COc1cc2ncnc(Nc3ccc(F)c(F)c3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P20 compound treatment 1245840.0 137000.0 0.67 1055520.0 -46300.0 -0.28 1039770.0 885.625 0.00507241047550774 0.2291 0.3173 2071435 Maybridge1_004046 COC(=O)c1sccc1NC(=O)CSCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P21 compound treatment 1234400.0 125000.0 0.61 1136090.0 34200.0 0.2 1011160.0 -27724.375 -0.158791147694459 0.3789 0.5708 2071436 Maybridge1_004047 Cn1ncc(C(=O)O/N=C/c2ccc(Cl)cc2Cl)c1n3cccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P22 compound treatment 1161660.0 52400.0 0.26 1108320.0 6460.0 0.04 955950.0 -82934.375 -0.475006004267819 -0.1042 -0.1927 1264484 Maybridge1_004048 CCOC(=O)C1C(CC(=CC1=O)c2cccs2)c3ccc(OC)c(OC)c3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P23 mock treatment 1192220.0 83000.0 0.41 1106830.0 4970.0 0.03 1119360.0 80475.625 0.460923532277242 0.5172 0.8417 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.552 P24 mock treatment 1053820.0 -55400.0 -0.27 1000900.0 -101000.0 -0.6 997350.0 -41534.375 -0.237887818030958 -0.6403 -0.9144 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A01 mock treatment 829350.0 -184000.0 -0.9 941050.0 -48600.0 -0.29 814020.0 -138417.741935484 -0.792786567892366 -1.1435 -0.9275 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A02 mock treatment 908730.0 -105000.0 -0.51 883740.0 -106000.0 -0.63 858290.0 -94147.741935484 -0.539230478406717 -0.9699 -0.9959 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A03 compound treatment 920440.0 -92900.0 -0.45 852530.0 -137000.0 -0.82 801440.0 -150997.741935484 -0.864838422550813 -1.232 -0.9684 2071437 Maybridge1_004049 ClC(Cl)(Cl)C(=O)Nc1c(Br)c(nn1c2ccccc2)C3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A04 compound treatment 931840.0 -81500.0 -0.4 889920.0 -99700.0 -0.59 822830.0 -129607.741935484 -0.742327359661768 -1.0008 -0.9715 1036161 Maybridge1_004050 Clc1ccc(C=C2c3ccccc3-c4ccccc24)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A05 compound treatment 969980.0 -43300.0 -0.21 870900.0 -119000.0 -0.71 841080.0 -111357.741935484 -0.637800622975229 -0.8981 -0.9214 2071438 Maybridge1_004051 Cc1ccc(cc1)S(=O)(=O)CCSc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A06 compound treatment 925030.0 -88300.0 -0.43 953200.0 -36400.0 -0.22 909440.0 -42997.741935484 -0.246269241063348 -0.5163 -0.9528 2071439 Maybridge1_004052 CCCc1cc(O)nc(SCc2ccccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A07 compound treatment 567370.0 -446000.0 -2.18 548450.0 -441000.0 -2.62 552340.0 -400097.741935484 -2.29155678466681 -4.0957 -0.9968 1618329 Maybridge1_004053 Cc1cc2[nH]c(cc(=O)n2n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A08 compound treatment 817680.0 -196000.0 -0.96 783140.0 -206000.0 -1.23 673380.0 -279057.741935484 -1.59830110200715 -2.1836 -0.9789 2071440 Maybridge1_004054 Cn1nc(nc1O)c2ccc(cc2)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A09 compound treatment 1052440.0 39100.0 0.19 1053760.0 64100.0 0.38 900190.0 -52247.741935484 -0.299248545959265 0.1578 0.3027 2071441 Maybridge1_004055 Cc1cc(NC(=O)Nc2ccccc2)n(n1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A10 compound treatment 873850.0 -139000.0 -0.68 865000.0 -125000.0 -0.74 670880.0 -281557.741935484 -1.6126198330601 -1.7524 -0.9218 2071442 Maybridge1_004056 COC(=O)c1ccc(Oc2cc(Cl)cc(Cl)c2)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A11 compound treatment 1004480.0 -8840.0 -0.04 1034950.0 45300.0 0.27 850810.0 -101627.741935484 -0.582072121717145 -0.2054 -0.3195 2071443 Maybridge1_004057 CNC(=O)Nc1cc(C)nn1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A12 compound treatment 857760.0 -156000.0 -0.76 884820.0 -105000.0 -0.62 672390.0 -280047.741935484 -1.60397131950412 -1.7247 -0.9168 2071444 Maybridge1_004058 CS/C(=N\C#N)/Nc1cccc(SC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A13 compound treatment 908720.0 -105000.0 -0.51 946330.0 -43300.0 -0.26 835130.0 -117307.741935484 -0.671879202881251 -0.8316 -0.9423 2071445 Maybridge1_004059 OCc1ccccc1C(=O)N/N=C/c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A14 compound treatment 868090.0 -145000.0 -0.71 873030.0 -117000.0 -0.69 720110.0 -232327.741935484 -1.3306553811654 -1.5782 -0.9509 1006104 Maybridge1_004060 Cc1cc(=O)oc2cc(O)cc(O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A15 compound treatment 909650.0 -104000.0 -0.51 919540.0 -70100.0 -0.42 839840.0 -112597.741935484 -0.644902713577492 -0.9054 -0.9843 2071446 Maybridge1_004061 Fc1ccc(NC(=S)N(CCC#N)Cc2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A16 compound treatment 1009220.0 -4100.0 -0.02 915940.0 -73700.0 -0.44 808170.0 -144267.741935484 -0.82629239855627 -0.7416 -0.7928 1043641 Maybridge1_004062 CCCCCCCOc1ccc(cc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A17 compound treatment 923040.0 -90300.0 -0.44 978560.0 -11100.0 -0.07 832860.0 -119577.741935484 -0.68488061067733 -0.6881 -0.8419 1282423 Maybridge1_004063 CSc1cccc(NC2OC(=O)c3ccccc23)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A18 compound treatment 994160.0 -19200.0 -0.09 964900.0 -24700.0 -0.15 950830.0 -1607.74193548399 -0.00920832975069822 -0.1443 -0.8264 1931114 Maybridge1_004064 [O-][N+](=O)c1ccc(cc1)c2ccc(I)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A19 compound treatment 973120.0 -40200.0 -0.2 901890.0 -87700.0 -0.52 911700.0 -40737.741935484 -0.233325108191481 -0.5493 -0.909 1159824 Maybridge1_004065 CCOC(=O)c1ccc(N2CCOCC2)c(NS(=O)(=O)c3ccc(F)cc3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A20 compound treatment 1006690.0 -6630.0 -0.03 1120340.0 131000.0 0.78 948990.0 -3447.74193548399 -0.0197469158056698 0.4187 0.538 1557241 Maybridge1_004066 CCn1c(O)cc(C)c(C#N)c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A21 compound treatment 837920.0 -175000.0 -0.86 966520.0 -23100.0 -0.14 850130.0 -102307.741935484 -0.585966816563548 -0.9124 -0.8713 1374202 Maybridge1_004067 CCOC(=O)c1ccc(N2CCOCC2)c(N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A22 compound treatment 859250.0 -154000.0 -0.75 960930.0 -28700.0 -0.17 816530.0 -135907.741935484 -0.778410561915203 -0.9826 -0.8963 1100255 Maybridge1_004068 Clc1ccc(C2NC(=O)Cc3ccccc23)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A23 compound treatment 826430.0 -187000.0 -0.91 860390.0 -129000.0 -0.77 835130.0 -117307.741935484 -0.671879202881251 -1.3588 -0.9921 1526172 Maybridge1_004069 O=C1OC(Nc2ccccc2SCc3ccc(C#N)cc3)c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 A24 compound treatment 747280.0 -266000.0 -1.3 786890.0 -203000.0 -1.21 837240.0 -115197.741935484 -0.659794193872561 -1.8274 -0.9661 2071447 Maybridge1_004070 Sc1nnc(SCCSc2nnc(S)s2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B01 mock treatment 989220.0 -24100.0 -0.12 1009120.0 19500.0 0.12 883220.0 -69217.741935484 -0.396444092346694 -0.23 -0.5354 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B02 mock treatment 941920.0 -71400.0 -0.35 927100.0 -62500.0 -0.37 784360.0 -168077.741935484 -0.962663993104572 -0.9719 -0.8922 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B03 compound treatment 969190.0 -44100.0 -0.22 933280.0 -56300.0 -0.34 903720.0 -48717.741935484 -0.279030497712499 -0.479 -0.9848 1069883 Maybridge1_004071 CS(=O)(=O)OC1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B04 compound treatment 925660.0 -87700.0 -0.43 886990.0 -103000.0 -0.61 836550.0 -115887.741935484 -0.663746163643175 -0.9829 -0.9846 1103910 Maybridge1_004072 COc1ccc(O)c(c1)C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B05 compound treatment 917220.0 -96100.0 -0.47 934940.0 -54700.0 -0.33 828090.0 -124347.741935484 -0.71220074952636 -0.87 -0.953 2071448 Maybridge1_004073 COc1cccc2c(OC(=O)C)coc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B06 compound treatment 1028450.0 15100.0 0.07 961220.0 -28400.0 -0.17 890240.0 -62197.741935484 -0.356237095550008 -0.2605 -0.6495 2071449 Maybridge1_004074 CCO[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B07 compound treatment 873440.0 -140000.0 -0.68 789560.0 -200000.0 -1.19 775200.0 -177237.741935484 -1.01512782368258 -1.6676 -0.977 2071450 Maybridge1_004075 [O-][N+](=O)c1ccc(cc1)C(=O)O/N=C/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B08 compound treatment 1031200.0 17900.0 0.09 998130.0 8500.0 0.05 958420.0 5982.25806451601 0.0342633377260597 0.0994 0.9326 1611061 Maybridge1_004076 CC(C)C(=O)Nc1ncnc2[nH]cnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B09 compound treatment 1057120.0 43800.0 0.21 988960.0 -668.0 0.0 887570.0 -64867.741935484 -0.37152950031456 -0.0933 -0.2175 1145454 Maybridge1_004077 Cc1ccc(cc1)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B10 compound treatment 757920.0 -255000.0 -1.25 769230.0 -220000.0 -1.31 675130.0 -277307.741935484 -1.58827799027009 -2.3941 -0.9943 2071451 Maybridge1_004078 C(=C/c1ccncc1)\c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B11 compound treatment 1059400.0 46100.0 0.23 956800.0 -32800.0 -0.2 875090.0 -77347.741935484 -0.443008605730889 -0.2385 -0.4467 2071452 Maybridge1_004079 O=C1CC23CC(=O)CC3(C1)CCCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B12 compound treatment 916550.0 -96800.0 -0.47 866930.0 -123000.0 -0.73 739920.0 -212517.741935484 -1.21719375630182 -1.397 -0.9339 1651448 Maybridge1_004080 COc1ccc(cc1)c2cc(C(=O)O)c3ccc(C)cc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B13 compound treatment 856130.0 -157000.0 -0.77 952430.0 -37200.0 -0.22 879200.0 -73237.741935484 -0.419468611879838 -0.8133 -0.901 2071453 Maybridge1_004081 Nc1c(Oc2ccccc2)cc(O)c3C(=O)c4ccccc4C(=O)c13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B14 compound treatment 926240.0 -87100.0 -0.43 1022410.0 32800.0 0.19 925390.0 -27047.741935484 -0.154915736945523 -0.2225 -0.4514 1287428 Maybridge1_004082 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3ccc(s3)c4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B15 compound treatment 1034360.0 21000.0 0.1 1040640.0 51000.0 0.3 969600.0 17162.258064516 0.0982967029948547 0.2912 0.8693 2071454 Maybridge1_004083 CN1CC(=O)N=C1NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B16 compound treatment 1023010.0 9690.0 0.05 1100490.0 111000.0 0.66 979920.0 27482.258064516 0.157404424781435 0.4988 0.7342 1639300 Maybridge1_004084 O=C(NCc1ccc2OCOc2c1)NC3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B17 compound treatment 998940.0 -14400.0 -0.07 1030110.0 40500.0 0.24 927770.0 -24667.741935484 -0.141284304983114 0.0168 0.0585 1269668 Maybridge1_004085 COc1ccccc1N2CCN(CC2)C(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B18 compound treatment 781360.0 -232000.0 -1.13 856640.0 -133000.0 -0.79 683130.0 -269307.741935484 -1.54245805090065 -2.0014 -0.9664 2071455 Maybridge1_004086 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)Nc3ccccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B19 compound treatment 980650.0 -32700.0 -0.16 1111770.0 122000.0 0.73 897830.0 -54607.741935484 -0.312765428073251 0.1466 0.1817 2071456 Maybridge1_004087 Cn1c2CCC/C(=N\OC(=O)C3CCCCC3)/c2c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B20 compound treatment 985610.0 -27700.0 -0.14 1083950.0 94300.0 0.56 901470.0 -50967.741935484 -0.291917355660154 0.0771 0.1193 2071457 Maybridge1_004088 Cc1cc(nn1C(C)(C)C)C(=O)NNC(=O)C2CCN(CC2)c3nccc(n3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B21 compound treatment 803040.0 -210000.0 -1.03 996320.0 6690.0 0.04 780640.0 -171797.741935484 -0.983970264911362 -1.1383 -0.7998 1010925 Maybridge1_004089 Sc1nc2ccccc2nc1S 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B22 compound treatment 877680.0 -136000.0 -0.66 958320.0 -31300.0 -0.19 883010.0 -69427.741935484 -0.397646865755142 -0.7197 -0.9053 1460321 Maybridge1_004090 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B23 compound treatment 971200.0 -42100.0 -0.21 1050890.0 61300.0 0.36 892600.0 -59837.741935484 -0.342720213436023 -0.1064 -0.1967 1196658 Maybridge1_004091 ON=C1CCN(Cc2ccccc2)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 B24 compound treatment 812400.0 -201000.0 -0.98 940040.0 -49600.0 -0.29 802720.0 -149717.741935484 -0.857507232251702 -1.2321 -0.922 1230437 Maybridge1_004092 OC(CSc1ccccc1)CN2CCN(CC2)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C01 mock treatment 940320.0 -73000.0 -0.36 894250.0 -95400.0 -0.57 886760.0 -65677.741935484 -0.376168769175716 -0.7506 -0.9768 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C02 mock treatment 989680.0 -23600.0 -0.12 943590.0 -46000.0 -0.27 896000.0 -56437.741935484 -0.32324673920401 -0.4114 -0.9369 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C03 compound treatment 1090960.0 77600.0 0.38 926160.0 -63500.0 -0.38 910410.0 -42027.741935484 -0.240713573414803 -0.1379 -0.235 1637319 Maybridge1_004093 CC(C)(C)C(=O)Nc1cc(nn1c2ccccc2)C3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C04 compound treatment 404350.0 -609000.0 -2.98 377660.0 -612000.0 -3.64 303550.0 -648887.741935484 -3.71649962413224 -5.9646 -0.9954 2071458 Maybridge1_004094 O/N=C(/c1ccccc1)\c2ccccc2\N=C\c3cc(Cl)cc(Cl)c3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C05 compound treatment 1116580.0 103000.0 0.5 1007650.0 18000.0 0.11 838790.0 -113647.741935484 -0.650916580619731 -0.0227 -0.0273 2071459 Maybridge1_004095 Cc1ccc(cc1)S(=O)(=O)CCSc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C06 compound treatment 976870.0 -36500.0 -0.18 931470.0 -58200.0 -0.35 810670.0 -141767.741935484 -0.81197366750332 -0.7713 -0.8567 2071460 Maybridge1_004096 Nc1ncnc(SCc2c(F)cccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C07 compound treatment 1123840.0 111000.0 0.54 981710.0 -7920.0 -0.05 855330.0 -97107.741935484 -0.55618385597341 -0.0365 -0.0471 2071461 Maybridge1_004097 Nc1cc(n[nH]1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C08 compound treatment 1066560.0 53200.0 0.26 1022720.0 33100.0 0.2 894720.0 -57717.741935484 -0.330577929503121 0.0729 0.157 2071462 Maybridge1_004098 CNC(=O)NNC(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C09 compound treatment 1139390.0 126000.0 0.62 1118880.0 129000.0 0.77 961190.0 8752.25806451601 0.050128491732729 0.8283 0.8399 2071463 Maybridge1_004099 Cc1cc(NC(=O)C(C)(C)C)n(C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C10 compound treatment 871260.0 -142000.0 -0.69 843760.0 -146000.0 -0.87 769660.0 -182777.741935484 -1.04685813169592 -1.5059 -0.9866 1569859 Maybridge1_004100 CC(C)c1ccc(Nc2cc(O)nn2C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C11 compound treatment 1175530.0 162000.0 0.79 1170040.0 180000.0 1.07 974910.0 22472.258064516 0.128709687751322 1.1513 0.8592 2071464 Maybridge1_004101 Cc1cc(NC(=O)c2ccccc2)n(C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C12 compound treatment 1061630.0 48300.0 0.24 1041780.0 52200.0 0.31 995870.0 43432.258064516 0.248757928899259 0.4589 0.9926 2071465 Maybridge1_004102 CN(C)/C=N/S(=O)(=O)c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C13 compound treatment 1062140.0 48800.0 0.24 1085060.0 95400.0 0.57 814990.0 -137447.741935484 -0.787230900243821 0.0108 0.0108 2071466 Maybridge1_004103 COc1ccc(cc1)C(=O)NNC(=O)C2C(C3CC2C=C3)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C14 compound treatment 1090350.0 77000.0 0.38 1030240.0 40600.0 0.24 910190.0 -42247.741935484 -0.241973621747463 0.217 0.4268 1005598 Maybridge1_004104 CC[n+]1c(C)ccc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C15 compound treatment 939320.0 -74000.0 -0.36 942730.0 -46900.0 -0.28 838140.0 -114297.741935484 -0.654639450693499 -0.7477 -0.9368 2071467 Maybridge1_004105 C/C(=N/NC(=O)N)/c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C16 compound treatment 692910.0 -320000.0 -1.57 785960.0 -204000.0 -1.21 588490.0 -363947.741935484 -2.08450793364114 -2.8066 -0.9764 1011181 Maybridge1_004106 c1ccc2c(c1)ccc3ncccc32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C17 compound treatment 959380.0 -53900.0 -0.26 1146810.0 157000.0 0.93 916740.0 -35697.741935484 -0.204458546388732 0.2694 0.2715 1703659 Maybridge1_004107 COc1cc2CCN=C(c3ccccc3NC(=O)c4ccc(F)cc4)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C18 compound treatment 871580.0 -142000.0 -0.69 1081670.0 92000.0 0.55 765500.0 -186937.741935484 -1.07068450016803 -0.702 -0.5059 1009943 Maybridge1_004108 O=C(Nc1cccc2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C19 compound treatment 883070.0 -130000.0 -0.64 1048860.0 59200.0 0.35 876390.0 -76047.741935484 -0.435562865583355 -0.4155 -0.4901 1418039 Maybridge1_004109 CCOC(=O)c1ccc(N2CCOCC2)c(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C20 compound treatment 49880.0 -963000.0 -4.71 60640.0 -929000.0 -5.52 32160.0 -920277.741935484 -5.27088379231634 -8.9503 -0.9978 1153807 Maybridge1_004110 OC(CN1CCCC1)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C21 compound treatment 864390.0 -149000.0 -0.73 1002410.0 12800.0 0.08 811640.0 -140797.741935484 -0.806417999854775 -0.8418 -0.7731 2071468 Maybridge1_004111 CCOC(=O)c1ccc(N2CCOCC2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C22 compound treatment 966980.0 -46300.0 -0.23 1186820.0 197000.0 1.17 925660.0 -26777.741935484 -0.153369313991805 0.4577 0.3802 1373411 Maybridge1_004112 Clc1ccccc1C2NC(=O)Cc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C23 compound treatment 601300.0 -412000.0 -2.01 602120.0 -388000.0 -2.3 572220.0 -380217.741935484 -2.17769423533375 -3.75 -0.9985 1111528 Maybridge1_004113 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 C24 compound treatment 932260.0 -81100.0 -0.4 1022930.0 33300.0 0.2 910040.0 -42397.741935484 -0.24283274561064 -0.2545 -0.504 2071469 Maybridge1_004114 C(CSc1nnc[nH]1)Sc2nnc[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D01 mock treatment 903170.0 -110000.0 -0.54 1016320.0 26700.0 0.16 836030.0 -116407.741935484 -0.666724459702189 -0.604 -0.6931 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D02 mock treatment 1111310.0 98000.0 0.48 1003220.0 13600.0 0.08 898960.0 -53477.741935484 -0.306293361637317 0.1462 0.2547 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D03 compound treatment 1001680.0 -11600.0 -0.06 917890.0 -71700.0 -0.43 858030.0 -94407.741935484 -0.540719626436224 -0.5913 -0.8556 1090692 Maybridge1_004115 CC1(CC2(C)CC3(C)C1)CC(Br)(C2)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D04 compound treatment 1004590.0 -8730.0 -0.04 929090.0 -60500.0 -0.36 808660.0 -143777.741935484 -0.823485927269892 -0.7079 -0.7868 2071470 Maybridge1_004116 Ic1cc(C#N)cc(I)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D05 compound treatment 1060590.0 47300.0 0.23 1069060.0 79400.0 0.47 856400.0 -96037.741935484 -0.550055439082748 0.0885 0.1163 2071471 Maybridge1_004117 Cc1ccc(cc1)S(=O)(=O)OCC(C)(C)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D06 compound treatment 1079540.0 66200.0 0.32 1071140.0 81500.0 0.48 1046020.0 93582.258064516 0.535991673821448 0.7761 0.9802 2071472 Maybridge1_004118 CC(=O)OC[C@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D07 compound treatment 1094010.0 80700.0 0.39 951000.0 -38600.0 -0.23 856160.0 -96277.741935484 -0.551430037263831 -0.2234 -0.3121 2071473 Maybridge1_004119 Brc1ccccc1C(=O)O/N=C/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D08 compound treatment 1052360.0 39000.0 0.19 962290.0 -27300.0 -0.16 905560.0 -46877.741935484 -0.268491911657527 -0.1388 -0.3778 2071474 Maybridge1_004120 CC(=O)O[C@@H]1CO[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D09 compound treatment 938640.0 -74700.0 -0.36 891460.0 -98200.0 -0.58 822740.0 -129697.741935484 -0.742842833979674 -0.9766 -0.9643 2071475 Maybridge1_004121 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D10 compound treatment 797630.0 -216000.0 -1.05 826460.0 -163000.0 -0.97 652130.0 -300307.741935484 -1.72001031595723 -2.1617 -0.9657 1269639 Maybridge1_004122 CCC(=O)Nc1cccc2c(NC(=O)CC)cccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D11 compound treatment 881440.0 -132000.0 -0.64 929790.0 -59800.0 -0.36 903860.0 -48577.741935484 -0.278228648773534 -0.7381 -0.938 1920748 Maybridge1_004123 CC(C)(C)c1cc(nc(N)n1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D12 compound treatment 720960.0 -292000.0 -1.43 681070.0 -309000.0 -1.83 698890.0 -253547.741935484 -1.45219277034285 -2.7225 -0.9931 2071476 Maybridge1_004124 COc1ccc(Br)cc1/C=N/N=C\2/C(=O)Nc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D13 compound treatment 1092130.0 78800.0 0.39 1138270.0 149000.0 0.88 872360.0 -80077.741935484 -0.458644660040711 0.4678 0.4382 2071477 Maybridge1_004125 CC(=O)C1C(=O)c2cccc([N+](=O)[O-])c2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D14 compound treatment 1055380.0 42100.0 0.21 1017790.0 28200.0 0.17 826660.0 -125777.741935484 -0.720391063688648 -0.2006 -0.2613 2071478 Maybridge1_004126 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)CSc4nccc(n4)c5cccs5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D15 compound treatment 732770.0 -281000.0 -1.37 690990.0 -299000.0 -1.78 705760.0 -246677.741935484 -1.41284489740934 -2.6324 -0.9929 2071479 Maybridge1_004127 CCOC(=O)/C(=N/Nc1ccc(C)cc1C)/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D16 compound treatment 978970.0 -34400.0 -0.17 1108110.0 118000.0 0.7 915530.0 -36907.741935484 -0.21138881221836 0.1878 0.2489 1309532 Maybridge1_004128 Cc1ccc(NC(=O)Nc2ccc3COC(=O)c3c2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D17 compound treatment 1045050.0 31700.0 0.16 1037380.0 47800.0 0.28 969060.0 16622.258064516 0.0952038570874174 0.3084 0.9145 2071480 Maybridge1_004129 O=c1[nH]ccn1Cc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D18 compound treatment 1064090.0 50800.0 0.25 1067520.0 77900.0 0.46 1029320.0 76882.258064516 0.440342550387738 0.6649 0.9698 2071481 Maybridge1_004130 OC(=O)CSCC(=O)Nc1ccc(Br)c(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D19 compound treatment 672010.0 -341000.0 -1.67 639440.0 -350000.0 -2.08 756510.0 -195927.741935484 -1.12217465703444 -2.813 -0.9719 2071482 Maybridge1_004131 Cn1c2CCC/C(=N\OC(=O)c3ccc(Cl)cc3Cl)/c2c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D20 compound treatment 900700.0 -113000.0 -0.55 1073870.0 84200.0 0.5 831770.0 -120667.741935484 -0.691123577416417 -0.4275 -0.4209 2071483 Maybridge1_004132 COC(=O)c1cc(NC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)ccc1N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D21 compound treatment 939520.0 -73800.0 -0.36 1068320.0 78700.0 0.47 836240.0 -116197.741935484 -0.665521686293741 -0.3223 -0.3621 1205234 Maybridge1_004133 CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D22 compound treatment 957150.0 -56200.0 -0.27 1088910.0 99300.0 0.59 801980.0 -150457.741935484 -0.861745576643376 -0.3151 -0.2918 1525016 Maybridge1_004134 OC(CSc1ccc(F)cc1)CN2CCN(CC2)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D23 compound treatment 816650.0 -197000.0 -0.96 874400.0 -115000.0 -0.69 777610.0 -174827.741935484 -1.00132456694754 -1.5285 -0.9876 2071484 Maybridge1_004135 CCOC(=O)/C(=N/Nc1ccccc1)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 D24 compound treatment 1021030.0 7710.0 0.04 1090320.0 101000.0 0.6 976290.0 23852.258064516 0.136613627292551 0.4463 0.7253 2071485 Maybridge1_004136 CC(=O)c1ccc(OCC(O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E01 mock treatment 1110200.0 96900.0 0.47 1033540.0 43900.0 0.26 1001730.0 49292.258064516 0.282321034487376 0.587 0.9626 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E02 mock treatment 1039530.0 26200.0 0.13 910170.0 -79500.0 -0.47 1057440.0 105002.258064516 0.601399637271326 0.1483 0.1913 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E03 compound treatment 1155740.0 142000.0 0.7 945170.0 -44500.0 -0.26 993090.0 40652.258064516 0.232835499968378 0.3835 0.4918 1157986 Maybridge1_004137 CCN(CCS(=O)(=O)c1ccc(C)cc1)S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E04 compound treatment 1154930.0 142000.0 0.69 901440.0 -88200.0 -0.52 1086690.0 134252.258064516 0.768928790590848 0.5406 0.4662 2071486 Maybridge1_004138 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCc3ccccc3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E05 compound treatment 612110.0 -401000.0 -1.96 612420.0 -377000.0 -2.24 568980.0 -383457.741935484 -2.19625131077837 -3.6948 -0.9983 1925341 Maybridge1_004139 Nc1cc(nn1c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E06 compound treatment 1241720.0 228000.0 1.12 1043800.0 54200.0 0.32 987540.0 35102.258064516 0.201047917030828 0.9463 0.8028 2071487 Maybridge1_004140 Nc1ncnc(SCc2ccc(Cl)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E07 compound treatment 1384800.0 371000.0 1.81 1042140.0 52500.0 0.31 944730.0 -7707.74193548399 -0.0441460335198976 1.2027 0.6529 2071488 Maybridge1_004141 Cc1cc2[nH]c(C)cc(=O)n2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E08 compound treatment 1260270.0 247000.0 1.21 991520.0 1890.0 0.01 943210.0 -9227.74193548399 -0.0528518220000916 0.6726 0.5569 2071489 Maybridge1_004142 CNC(=O)NNC(=O)c1cccnc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E09 compound treatment 1235690.0 222000.0 1.09 1085060.0 95400.0 0.57 977670.0 25232.258064516 0.144517566833779 1.0383 0.8413 1549660 Maybridge1_004143 CC1CCCCN1Cc2c(C)n(C)n(c3ccccc3)c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E10 compound treatment 992960.0 -20400.0 -0.1 934240.0 -55400.0 -0.33 917400.0 -35037.741935484 -0.200678401390753 -0.3635 -0.9125 1568475 Maybridge1_004144 Cn1nc(O)cc1Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E11 compound treatment 933360.0 -80000.0 -0.39 798460.0 -191000.0 -1.14 835360.0 -117077.741935484 -0.67056187962438 -1.269 -0.922 2071490 Maybridge1_004145 CCc1ccc(NC(=S)Nc2cc(C)cc(C)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E12 compound treatment 1085120.0 71800.0 0.35 963460.0 -26200.0 -0.16 1034440.0 82002.258064516 0.469667311584181 0.3838 0.6329 1731945 Maybridge1_004146 COc1cc(CCC(C)N)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E13 compound treatment 1247710.0 234000.0 1.15 1122950.0 133000.0 0.79 976680.0 24242.258064516 0.138847349336811 1.1991 0.8566 2071491 Maybridge1_004147 OC(=O)C1C(C2CC1C=C2)C(=O)NNC(=O)CCc3ccc(O)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E14 compound treatment 1299650.0 286000.0 1.4 1039170.0 49500.0 0.29 946770.0 -5667.74193548399 -0.03246194898069 0.959 0.6707 43143 Maybridge1_004148 O[C@@H](C(=O)O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E15 compound treatment 1082800.0 69500.0 0.34 1060690.0 71100.0 0.42 927540.0 -24897.741935484 -0.142601628239986 0.3576 0.6381 2071492 Maybridge1_004149 COc1cc2CCC(=O)c2c(OC)c1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E16 compound treatment 1019470.0 6150.0 0.03 1164120.0 174000.0 1.04 895540.0 -56897.741935484 -0.325881385717753 0.4283 0.3936 1022845 Maybridge1_004150 CC(=O)Nc1ncc(s1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E17 compound treatment 941830.0 -71500.0 -0.35 1124410.0 135000.0 0.8 828900.0 -123537.741935484 -0.707561480665204 -0.1474 -0.1311 2071493 Maybridge1_004151 CC(=O)c1ccc(Sc2ccccc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E18 compound treatment 787560.0 -226000.0 -1.1 726460.0 -263000.0 -1.56 608890.0 -343547.741935484 -1.96766708824907 -2.6764 -0.9748 1503681 Maybridge1_004152 OC(CN1CCCC1)Cn2c3ccccc3c4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E19 compound treatment 485520.0 -528000.0 -2.58 502990.0 -487000.0 -2.89 435550.0 -516887.741935484 -2.96047062453645 -4.8688 -0.9983 1399804 Maybridge1_004153 CCOC(=O)c1ccc(N2CCOCC2)c(NC(=O)c3c(C)onc3c4ccccc4)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E20 compound treatment 1017630.0 4310.0 0.02 1015520.0 25900.0 0.15 946360.0 -6077.74193548399 -0.0348102208733739 0.0809 0.5083 2071494 Maybridge1_004154 OC1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E21 compound treatment 936870.0 -76500.0 -0.37 1218610.0 229000.0 1.36 970190.0 17752.258064516 0.101675923523351 0.6292 0.4445 2071495 Maybridge1_004155 [O-][N+](=O)c1ccc(NC2OC(=O)c3ccccc23)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E22 compound treatment 686420.0 -327000.0 -1.6 795300.0 -194000.0 -1.16 646830.0 -305607.741935484 -1.75036602578949 -2.5999 -0.9862 1498806 Maybridge1_004156 Brc1ccc(cc1)C2NC(=O)Cc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E23 compound treatment 591630.0 -422000.0 -2.06 800160.0 -189000.0 -1.13 616370.0 -336067.741935484 -1.92482544493864 -2.9513 -0.972 2071496 Maybridge1_004157 Nc1ccccc1SCc2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 E24 compound treatment 914290.0 -99000.0 -0.48 1229040.0 239000.0 1.42 892570.0 -59867.741935484 -0.342892038208659 0.3446 0.2235 1082377 Maybridge1_004158 CC1(O)C2CC3CC(C2)CC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F01 mock treatment 1019460.0 6140.0 0.03 927140.0 -62500.0 -0.37 891360.0 -61077.741935484 -0.349822304038287 -0.3992 -0.7809 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F02 mock treatment 1048320.0 35000.0 0.17 1043710.0 54100.0 0.32 899040.0 -53397.741935484 -0.305835162243622 0.1078 0.2267 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F03 compound treatment 614080.0 -399000.0 -1.95 588850.0 -401000.0 -2.38 554210.0 -398227.741935484 -2.2808463738392 -3.819 -0.9965 1462680 Maybridge1_004159 CC(=O)Oc1cc(CO)cc(OC(=O)C)c1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F04 compound treatment 393800.0 -620000.0 -3.03 336330.0 -653000.0 -3.88 328820.0 -623617.741935484 -3.57176589064901 -6.0527 -0.9949 1021543 Maybridge1_004160 Oc1cc(nc2ccccc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F05 compound treatment 952200.0 -61100.0 -0.3 768480.0 -221000.0 -1.32 803150.0 -149287.741935484 -0.855044410510595 -1.4253 -0.8926 2071497 Maybridge1_004161 O=C1c2cccc(Oc3ccccc3)c2C(=O)c4c(Oc5ccccc5)cccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F06 compound treatment 1136030.0 123000.0 0.6 980180.0 -9450.0 -0.06 974040.0 21602.258064516 0.123726769344895 0.3851 0.6265 2071498 Maybridge1_004162 CC(=O)OC[C@@H](OC(=O)C)C(O[C@@H]1O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F07 compound treatment 896860.0 -116000.0 -0.57 727140.0 -262000.0 -1.56 812500.0 -139937.741935484 -0.80149235637256 -1.6925 -0.9175 2071499 Maybridge1_004163 Clc1ccc(cc1)C(=O)O/N=C/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F08 compound treatment 1028810.0 15500.0 0.08 1020510.0 30900.0 0.18 914360.0 -38077.741935484 -0.218089978351141 0.0238 0.0807 2071500 Maybridge1_004164 CC(=O)O[C@H]1CO[C@@H](C#N)[C@H](OC(=O)C)[C@H]1OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F09 compound treatment 966110.0 -47200.0 -0.23 1013460.0 23800.0 0.14 876600.0 -75837.741935484 -0.434360092174907 -0.3021 -0.5903 1240231 Maybridge1_004165 Clc1ccc(cc1)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F10 compound treatment 54480.0 -959000.0 -4.68 52430.0 -937000.0 -5.57 33540.0 -918897.741935484 -5.26297985277511 -8.961 -0.9975 2071501 Maybridge1_004166 Cc1ccc(cc1)/C(=C/2\C=C(\Br)/C(=N/O)/C=C2/Cl)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F11 compound treatment 774610.0 -239000.0 -1.17 822460.0 -167000.0 -0.99 755360.0 -197077.741935484 -1.1287612733188 -1.899 -0.9977 1722183 Maybridge1_004167 C(N1CCOCC1)n2cnc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F12 compound treatment 679460.0 -334000.0 -1.63 689610.0 -300000.0 -1.78 818460.0 -133977.741935484 -0.767356501542326 -2.4148 -0.9521 2071502 Maybridge1_004168 Oc1c(Br)cc(Br)cc1/C=N/N=C\2/C(=O)Nc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F13 compound treatment 1159290.0 146000.0 0.71 1151680.0 162000.0 0.96 981610.0 29172.258064516 0.167083886973229 1.0646 0.8795 1075384 Maybridge1_004169 O=C1C(C#N)C(=O)c2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F14 compound treatment 1001990.0 -11300.0 -0.06 995060.0 5430.0 0.03 1272130.0 319692.258064516 1.83103498517451 1.0438 0.5697 2071503 Maybridge1_004170 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4cccc(Cl)c4)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F15 compound treatment 804830.0 -208000.0 -1.02 797280.0 -192000.0 -1.14 801350.0 -151087.741935484 -0.865353896868719 -1.7481 -0.9937 2071504 Maybridge1_004171 CCOC(=O)/C(=N/Nc1ccc(OC)cc1)/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F16 compound treatment 947800.0 -65500.0 -0.32 999120.0 9490.0 0.06 836010.0 -116427.741935484 -0.666839009550612 -0.5372 -0.7242 1030966 Maybridge1_004172 O=C(NCc1ccco1)Nc2cccc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F17 compound treatment 1054430.0 41100.0 0.2 963160.0 -26500.0 -0.16 952600.0 162.258064516005 9.29331834790792E-4 0.0256 0.1004 2071505 Maybridge1_004173 CC1[C@@H]([C@H]1C(=O)NN)C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F18 compound treatment 1139400.0 126000.0 0.62 1121410.0 132000.0 0.78 909800.0 -42637.741935484 -0.244207343791723 0.6671 0.65 1204063 Maybridge1_004174 Cc1onc(c1C(=O)Nc2ccc3OCCOc3c2)c4c(Cl)cccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F19 compound treatment 731090.0 -282000.0 -1.38 643970.0 -346000.0 -2.06 768320.0 -184117.741935484 -1.0545329715403 -2.5917 -0.9633 2071506 Maybridge1_004175 Cn1c2CCC/C(=N\OC(=O)c3cccc(c3)C(F)(F)F)/c2c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F20 compound treatment 795150.0 -218000.0 -1.07 1025060.0 35400.0 0.21 738100.0 -214337.741935484 -1.22761779250837 -1.2025 -0.7335 2071507 Maybridge1_004176 Cc1c(sc2ccc(Cl)cc12)C(=O)CN3CCN(CC3)c4ccc(cn4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F21 compound treatment 781330.0 -232000.0 -1.13 898310.0 -91300.0 -0.54 738430.0 -214007.741935484 -1.22572772000938 -1.6756 -0.9544 1019643 Maybridge1_004177 Clc1ccc2ocnc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F22 compound treatment 870080.0 -143000.0 -0.7 1052270.0 62600.0 0.37 911000.0 -41437.741935484 -0.237334352886307 -0.326 -0.3939 2071508 Maybridge1_004178 Cc1cc(Cl)cc(Br)c1OCC(O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F23 compound treatment 625230.0 -388000.0 -1.9 706830.0 -283000.0 -1.68 620040.0 -332397.741935484 -1.90380554775291 -3.1648 -0.9984 1046573 Maybridge1_004179 CCOC(=O)C(=CNc1ccccc1Cl)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 F24 compound treatment 987460.0 -25900.0 -0.13 991420.0 1790.0 0.01 910720.0 -41717.741935484 -0.238938050764237 -0.2048 -0.7569 2071509 Maybridge1_004180 CC(=O)c1ccc(OCC(O)CN2CCC(CC2)C(=O)N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G01 mock treatment 1159650.0 146000.0 0.71 1056290.0 66700.0 0.4 1111110.0 158672.258064516 0.908794155516069 1.1663 0.9542 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G02 mock treatment 1082410.0 69100.0 0.34 1083900.0 94300.0 0.56 1112420.0 159982.258064516 0.916297170587816 1.0476 0.9304 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G03 compound treatment 905820.0 -108000.0 -0.53 838430.0 -151000.0 -0.9 758630.0 -193807.741935484 -1.11003237310154 -1.4632 -0.9614 2071510 Maybridge1_004181 N/C(=C(\NCc1cccc(Cl)c1)/C#N)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G04 compound treatment 1035200.0 21900.0 0.11 967740.0 -21900.0 -0.13 920390.0 -32047.741935484 -0.183553199051425 -0.1194 -0.4793 2071511 Maybridge1_004182 COc1cc(cc(OC)c1OC)C(=O)NNC(=O)c2ccc(Cl)c(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G05 compound treatment 227150.0 -786000.0 -3.84 201380.0 -788000.0 -4.69 191790.0 -760647.741935484 -4.35660417712334 -7.4392 -0.9967 1083345 Maybridge1_004183 Cc1ccc(cc1)S(=O)(=O)C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G06 compound treatment 1134790.0 121000.0 0.59 1102260.0 113000.0 0.67 903100.0 -49337.741935484 -0.282581543013631 0.5662 0.6033 2071512 Maybridge1_004184 Nc1ncnc(SCc2c(Cl)cccc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G07 compound treatment 1145120.0 132000.0 0.64 1039910.0 50300.0 0.3 922980.0 -29457.741935484 -0.168718993680568 0.447 0.6125 1456405 Maybridge1_004185 CCN(CCS(=O)(=O)c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G08 compound treatment 1187310.0 174000.0 0.85 936640.0 -53000.0 -0.32 946630.0 -5807.74193548399 -0.0332637979196552 0.2897 0.3193 2071513 Maybridge1_004186 Cn1nc(O)cc1C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G09 compound treatment 1124480.0 111000.0 0.54 1214400.0 225000.0 1.34 949780.0 -2657.74193548399 -0.0152221967929375 1.0765 0.7461 1143794 Maybridge1_004187 CC1CCCN(Cc2c(C)n(C)n(c3ccccc3)c2=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G10 compound treatment 1196240.0 183000.0 0.89 1103810.0 114000.0 0.68 905690.0 -46747.741935484 -0.267747337642774 0.7534 0.6529 2071514 Maybridge1_004188 CSc1nc(N)n(n1)c2c(Cl)cc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G11 compound treatment 882760.0 -131000.0 -0.64 906040.0 -83600.0 -0.5 778200.0 -174237.741935484 -0.997945346419042 -1.2314 -0.9587 1296321 Maybridge1_004189 Cc1ccc(NC(=S)Nc2cc(C)cc(C)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G12 compound treatment 804580.0 -209000.0 -1.02 803790.0 -186000.0 -1.11 671260.0 -281177.741935484 -1.61044338594006 -2.1566 -0.9788 2071515 Maybridge1_004190 Cc1nn(c(O)c1C(=O)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G13 compound treatment 1219840.0 207000.0 1.01 1254640.0 265000.0 1.58 1183250.0 230812.258064516 1.32197545878001 2.2556 0.9845 1087761 Maybridge1_004191 NNC(=O)c1ccccc1CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G14 compound treatment 249040.0 -764000.0 -3.73 292400.0 -697000.0 -4.15 296800.0 -655637.741935484 -3.75516019797521 -6.7177 -0.9988 1005858 Maybridge1_004192 CC1=NN(C(=O)C1[N+](=O)[O-])c2ccc(cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G15 compound treatment 1067840.0 54500.0 0.27 1231930.0 242000.0 1.44 909760.0 -42677.741935484 -0.24443644348857 0.8445 0.5685 2071516 Maybridge1_004193 Clc1ccc(cc1)C2=NN(C(C2)c3cccs3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G16 compound treatment 1050520.0 37200.0 0.18 1220740.0 231000.0 1.37 895520.0 -56917.741935484 -0.325995935566177 0.7102 0.4987 1103751 Maybridge1_004194 OCC(NC(=O)c1ccccc1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G17 compound treatment 982400.0 -30900.0 -0.15 1101440.0 112000.0 0.66 924000.0 -28437.741935484 -0.162876951410964 0.2026 0.289 1436971 Maybridge1_004195 Cc1ccc(cc1)S(=O)(=O)Nc2sc3CCCCc3c2C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G18 compound treatment 881080.0 -132000.0 -0.65 1069200.0 79600.0 0.47 850560.0 -101877.741935484 -0.58350399482244 -0.4367 -0.4407 1642807 Maybridge1_004196 COc1cc2CC(=O)NC(c3ccc(Cl)cc3)c2cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G19 compound treatment 1101250.0 87900.0 0.43 1065530.0 75900.0 0.45 1152800.0 200362.258064516 1.14757331455507 1.1712 0.8969 2071517 Maybridge1_004197 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3c(O)ccc4ccccc34)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G20 compound treatment 903780.0 -110000.0 -0.54 1075170.0 85500.0 0.51 867520.0 -84917.741935484 -0.486365723359223 -0.2961 -0.3349 1049679 Maybridge1_004198 CNc1ccc(cc1)S(=O)(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G21 compound treatment 1004130.0 -9190.0 -0.04 1167380.0 178000.0 1.06 895230.0 -57207.741935484 -0.327656908368319 0.3952 0.3568 2071518 Maybridge1_004199 CCOC(=O)c1ccc(SCC(=O)Nc2c(C)cc(C)cc2C)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G22 compound treatment 671230.0 -342000.0 -1.67 785890.0 -204000.0 -1.21 631150.0 -321287.741935484 -1.84017310695359 -2.7269 -0.9861 1448022 Maybridge1_004200 Clc1ccc(cc1)C2NC(=O)Cc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G23 compound treatment 790460.0 -223000.0 -1.09 832980.0 -157000.0 -0.93 781520.0 -170917.741935484 -0.978930071580723 -1.7317 -0.9978 2071519 Maybridge1_004201 [O-][N+](=O)c1cc(Cl)ccc1Sc2ccccc2NC3OC(=O)c4ccccc34 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 G24 compound treatment 942480.0 -70800.0 -0.35 1076640.0 87000.0 0.52 986490.0 34052.258064516 0.195034049988589 0.2115 0.3242 2071520 Maybridge1_004202 CC(C)c1cccc(C(C)C)c1N=C=Nc2c(cccc2C(C)C)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H01 mock treatment 1007270.0 -6050.0 -0.03 1096570.0 107000.0 0.64 963000.0 10562.258064516 0.0604952530150652 0.385 0.6021 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H02 mock treatment 1062510.0 49200.0 0.24 1021300.0 31700.0 0.19 1066510.0 114072.258064516 0.653347993531431 0.6247 0.8662 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H03 compound treatment 839410.0 -174000.0 -0.85 839940.0 -150000.0 -0.89 745820.0 -206617.741935484 -1.18340155101686 -1.6877 -0.9886 1446039 Maybridge1_004203 CCN(CC)c1cccc(NC(=O)C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H04 compound treatment 1136320.0 123000.0 0.6 984590.0 -5040.0 -0.03 901280.0 -51157.741935484 -0.293005579220179 0.1605 0.2398 2071521 Maybridge1_004204 O=C(CCN1C(=O)c2ccccc2C1=O)CCC(=O)CCN3C(=O)c4ccccc4C3=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H05 compound treatment 822120.0 -191000.0 -0.93 751200.0 -238000.0 -1.42 637920.0 -314517.741935484 -1.8013979832622 -2.398 -0.9687 2071522 Maybridge1_004205 Cc1cc(C)c(N=C=Nc2c(C)cc(C)cc2C)c(C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H06 compound treatment 1045010.0 31700.0 0.15 979240.0 -10400.0 -0.06 905060.0 -47377.741935484 -0.271355657868117 -0.1029 -0.3233 2071523 Maybridge1_004206 NC(=O)N[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H07 compound treatment 1124480.0 111000.0 0.54 826640.0 -163000.0 -0.97 907300.0 -45137.741935484 -0.258526074844674 -0.3953 -0.3465 2071524 Maybridge1_004207 O=C(O/N=C/c1ccc2OCOc2c1)c3ccco3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H08 compound treatment 909710.0 -104000.0 -0.51 847430.0 -142000.0 -0.85 814900.0 -137537.741935484 -0.787746374561727 -1.2353 -0.9791 2071525 Maybridge1_004208 OC(C(O)C(=O)OCc1ccccc1)C(=O)OCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H09 compound treatment 908160.0 -105000.0 -0.51 875920.0 -114000.0 -0.68 839620.0 -112817.741935484 -0.646162761910152 -1.0601 -0.9934 1356101 Maybridge1_004209 Clc1cccc(c1Cl)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H10 compound treatment 973290.0 -40000.0 -0.2 1146810.0 157000.0 0.93 1010240.0 57802.258064516 0.331061994991619 0.6179 0.6113 2071526 Maybridge1_004210 O/N=C/C(=O)Nc1ccccc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H11 compound treatment 873660.0 -140000.0 -0.68 848700.0 -141000.0 -0.84 821380.0 -131057.741935484 -0.750632223672479 -1.3112 -0.9965 1312285 Maybridge1_004211 C(N1CCCCC1)n2cnc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H12 compound treatment 73570.0 -940000.0 -4.59 101720.0 -888000.0 -5.28 105640.0 -846797.741935484 -4.85002764920802 -8.4995 -0.9983 1112784 Maybridge1_004212 ON=C1C=CC(=C(C#N)c2ccccc2)C=C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H13 compound treatment 703520.0 -310000.0 -1.51 657920.0 -332000.0 -1.97 649090.0 -303347.741935484 -1.73742189291762 -3.0158 -0.9943 1055766 Maybridge1_004213 c1cc(oc1c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H14 compound treatment 1070240.0 56900.0 0.28 1073980.0 84400.0 0.5 836880.0 -115557.741935484 -0.661856091144186 0.068 0.0777 1533369 Maybridge1_004214 Clc1cccc(Oc2cccc(c2)S(=O)(=O)NCc3ccc4OCOc4c3)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H15 compound treatment 800500.0 -213000.0 -1.04 836430.0 -153000.0 -0.91 715840.0 -236597.741935484 -1.35511177380384 -1.9087 -0.986 2071527 Maybridge1_004215 CCOC(=O)/C(=N/Nc1ccc(Br)cc1)/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H16 compound treatment 1120200.0 107000.0 0.52 1224280.0 235000.0 1.4 1105790.0 153352.258064516 0.878323895835391 1.6142 0.9333 1284097 Maybridge1_004216 O=C(NCc1ccco1)NC2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H17 compound treatment 923230.0 -90100.0 -0.44 1183120.0 193000.0 1.15 918830.0 -33607.741935484 -0.192488087228466 0.299 0.2398 2071528 Maybridge1_004217 CC(C)(C)OC(=O)N1CCC(=O)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H18 compound treatment 935520.0 -77800.0 -0.38 1154510.0 165000.0 0.98 838530.0 -113907.741935484 -0.652405728649238 -0.0301 -0.0243 2071529 Maybridge1_004218 FC(F)(F)c1oc(cc1C(=O)Nc2ccc3OCCOc3c2)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H19 compound treatment 703070.0 -310000.0 -1.52 838080.0 -152000.0 -0.9 717550.0 -234887.741935484 -1.34531776176362 -2.1722 -0.9793 2071530 Maybridge1_004219 Cn1c2CCC/C(=N\OC(=O)c3ccc(cc3)C(C)(C)C)/c2c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H20 compound treatment 710770.0 -303000.0 -1.48 814510.0 -175000.0 -1.04 620440.0 -331997.741935484 -1.90151455078444 -2.5525 -0.9728 1178132 Maybridge1_004220 Fc1ccc(F)c(NC(=O)N2CCN(CC2)c3ccnc4cc(Cl)ccc34)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H21 compound treatment 919950.0 -93400.0 -0.46 1122090.0 132000.0 0.79 858140.0 -94297.741935484 -0.540089602269894 -0.1204 -0.1138 2071531 Maybridge1_004221 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H22 compound treatment 594720.0 -419000.0 -2.05 600970.0 -389000.0 -2.31 614370.0 -338067.741935484 -1.936280429781 -3.6331 -0.9972 2071532 Maybridge1_004222 Oc1ccc(cc1)n2nnnc2SCc3ccc(OC(F)(F)F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H23 compound treatment 834250.0 -179000.0 -0.87 1026020.0 36400.0 0.22 997640.0 45202.258064516 0.258895590484748 -0.2307 -0.246 1580966 Maybridge1_004223 COc1ccccc1N2CCN(Cc3ccc(F)cc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 H24 compound treatment 932570.0 -80800.0 -0.39 993160.0 3530.0 0.02 1023130.0 70692.258064516 0.404889372300633 0.0181 0.032 2071533 Maybridge1_004224 CC(=O)c1ccc(OCC(O)CN2CCN(CC2)C(c3ccccc3)c4ccccc4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I01 mock treatment 945830.0 -67500.0 -0.33 996890.0 7260.0 0.04 1037010.0 84572.258064516 0.484386967106614 0.1142 0.1944 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I02 mock treatment 1002560.0 -10800.0 -0.05 1008160.0 18500.0 0.11 1025240.0 72802.258064516 0.416974381309323 0.274 0.6306 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I03 compound treatment 963490.0 -49800.0 -0.24 835680.0 -154000.0 -0.92 856330.0 -96107.741935484 -0.55045636355223 -0.9869 -0.9008 2071534 Maybridge1_004225 NC(=O)c1nnc2cc(nn2c1c3ccccc3Cl)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I04 compound treatment 985480.0 -27800.0 -0.14 963080.0 -26500.0 -0.16 967740.0 15302.258064516 0.0876435670914595 -0.1191 -0.5268 2071535 Maybridge1_004226 Cc1onc(c1C(=O)NNC(=O)c2c(C)onc2c3ccccc3Cl)c4ccccc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I05 compound treatment 923450.0 -89900.0 -0.44 871950.0 -118000.0 -0.7 930840.0 -21597.741935484 -0.123700903250091 -0.729 -0.8726 2071536 Maybridge1_004227 Cc1cc(NC(=O)C(Cl)(Cl)Cl)n(n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I06 compound treatment 983330.0 -30000.0 -0.15 940440.0 -49200.0 -0.29 914900.0 -37537.741935484 -0.214997132443704 -0.3776 -0.9646 1731523 Maybridge1_004228 CC(C)(C)c1ccc(OC(C)(C)C(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I07 compound treatment 911920.0 -101000.0 -0.5 888390.0 -101000.0 -0.6 1032330.0 79892.258064516 0.457582302575491 -0.3694 -0.4087 2071537 Maybridge1_004229 Clc1ccc(cc1)S(=O)(=O)CCSc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I08 compound treatment 1157600.0 144000.0 0.7 989560.0 -67.5 0.0 1001870.0 49432.258064516 0.283122883426341 0.5702 0.7506 1664186 Maybridge1_004230 Clc1ccc(cc1)c2n[nH]c(=S)[nH]c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I09 compound treatment 998470.0 -14900.0 -0.07 1026890.0 37300.0 0.22 888970.0 -63467.741935484 -0.363511010924907 -0.1238 -0.2868 1328726 Maybridge1_004231 Cc1nn(C)c(NC(=O)c2ccccc2Cl)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I10 compound treatment 979750.0 -33600.0 -0.16 974720.0 -14900.0 -0.09 861830.0 -90607.741935484 -0.518955155235739 -0.4455 -0.8079 2071538 Maybridge1_004232 CSc1nc(N)n(n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I11 compound treatment 907110.0 -106000.0 -0.52 804750.0 -185000.0 -1.1 830370.0 -122067.741935484 -0.699142066806069 -1.338 -0.9541 2071539 Maybridge1_004233 Cc1cc(C)cc(NC(=S)Nc2cccc(Cl)c2C)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I12 compound treatment 1070410.0 57100.0 0.28 966160.0 -23500.0 -0.14 1062430.0 109992.258064516 0.629979824453016 0.4442 0.6319 1056014 Maybridge1_004234 OCc1ccccc1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I13 compound treatment 767060.0 -246000.0 -1.2 836880.0 -153000.0 -0.91 824400.0 -128037.741935484 -0.733335196560515 -1.6425 -0.9797 2071540 Maybridge1_004235 Clc1ccc(NC(=O)C(=O)NCc2ccncc2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I14 compound treatment 1203870.0 191000.0 0.93 1141820.0 152000.0 0.91 996000.0 43562.258064516 0.249502502914013 1.2041 0.9107 2071541 Maybridge1_004236 CC1(C)COC2(CCC(=O)CC2)OC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I15 compound treatment 925320.0 -88000.0 -0.43 980400.0 -9230.0 -0.05 948900.0 -3537.74193548399 -0.0202623901235761 -0.2916 -0.672 1261522 Maybridge1_004237 Cc1cccnc1NC2OC(=O)c3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I16 compound treatment 822170.0 -191000.0 -0.93 1102240.0 113000.0 0.67 758020.0 -194417.741935484 -1.11352614347846 -0.7955 -0.4971 1531996 Maybridge1_004238 COC(=O)C(Cc1cccc(C)n1)(c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I17 compound treatment 839450.0 -174000.0 -0.85 1037500.0 47900.0 0.28 1182790.0 230352.258064516 1.31934081226627 0.4356 0.2731 2071542 Maybridge1_004239 CC(=O)c1ccc(Sc2ccccn2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I18 compound treatment 672800.0 -341000.0 -1.66 648750.0 -341000.0 -2.03 653500.0 -298937.741935484 -1.71216365134022 -3.1194 -0.996 1118153 Maybridge1_004240 Cc1c(sc(N)c1C(=O)N)C(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I19 compound treatment 651850.0 -361000.0 -1.77 792540.0 -197000.0 -1.17 599100.0 -353337.741935484 -2.02373923905242 -2.8647 -0.9775 2071543 Maybridge1_004241 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Br)ccc3O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I20 compound treatment 756160.0 -257000.0 -1.26 809600.0 -180000.0 -1.07 682560.0 -269877.741935484 -1.54572272158072 -2.2359 -0.9887 1231395 Maybridge1_004242 O=C(Cc1ccccc1)Nc2ccc3ccccc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I21 compound treatment 851040.0 -162000.0 -0.79 990310.0 683.0 0.0 976740.0 24302.258064516 0.139190998882082 -0.3751 -0.4659 2071544 Maybridge1_004243 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I22 compound treatment 337600.0 -676000.0 -3.3 425440.0 -564000.0 -3.35 442430.0 -510007.741935484 -2.92106547667873 -5.5296 -0.9982 1627134 Maybridge1_004244 Nc1nc(cs1)c2ccc-3c(Cc4ccccc43)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I23 compound treatment 860830.0 -152000.0 -0.75 1077620.0 88000.0 0.52 1044840.0 92402.258064516 0.529233232764455 0.1775 0.1685 1549155 Maybridge1_004245 Cc1c(C)c(C)c(CSc2ccccc2NC3OC(=O)c4ccccc34)c(C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 I24 compound treatment 898320.0 -115000.0 -0.56 1025620.0 36000.0 0.21 925070.0 -27367.741935484 -0.156748534520301 -0.2913 -0.4689 2071545 Maybridge1_004246 COC(=O)C(COS(=O)(=O)c1ccc(C)cc1)NC(=O)OC(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J01 mock treatment 1030270.0 16900.0 0.08 1070630.0 81000.0 0.48 955040.0 2602.25806451601 0.0149044133424706 0.3345 0.6841 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J02 mock treatment 945830.0 -67500.0 -0.33 981040.0 -8590.0 -0.05 898400.0 -54037.741935484 -0.309500757393178 -0.3986 -0.8757 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J03 compound treatment 1068090.0 54800.0 0.27 915140.0 -74500.0 -0.44 885370.0 -67067.741935484 -0.384129983641156 -0.323 -0.5012 2071546 Maybridge1_004247 C(C1=N[C@@H]([C@@H](O1)c2ccccc2)c3ccccc3)C4=N[C@@H]([C@@H](O4)c5ccccc5)c6ccccc6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J04 compound treatment 864960.0 -148000.0 -0.72 722940.0 -267000.0 -1.59 706190.0 -246247.741935484 -1.41038207566823 -2.1484 -0.958 2071547 Maybridge1_004248 OC[C@H]1O[C@H](O)[C@H](NNc2ccccc2)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J05 compound treatment 1144340.0 131000.0 0.64 946370.0 -43300.0 -0.26 1035520.0 83082.258064516 0.475853003399056 0.4958 0.5916 1069755 Maybridge1_004249 COc1cc(OC)c(OC)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J06 compound treatment 1106490.0 93200.0 0.46 1014750.0 25100.0 0.15 972760.0 20322.258064516 0.116395579045784 0.4163 0.8443 2071548 Maybridge1_004250 CC(=O)OC[C@H]1O[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J07 compound treatment 870140.0 -143000.0 -0.7 808720.0 -181000.0 -1.08 771690.0 -180747.741935484 -1.03523132208093 -1.6227 -0.9842 2071549 Maybridge1_004251 Clc1ccc(C(=O)O/N=C/c2ccc3OCOc3c2)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J08 compound treatment 1050880.0 37600.0 0.18 1006370.0 16700.0 0.1 947800.0 -4637.74193548399 -0.0265626317868743 0.1481 0.7037 2071550 Maybridge1_004252 CCSC(SCC)[C@H](O)[C@@H](O)[C@@H](O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J09 compound treatment 1144640.0 131000.0 0.64 953660.0 -36000.0 -0.21 913960.0 -38477.741935484 -0.220380975319613 0.1197 0.1683 1215373 Maybridge1_004253 Cc1ccc(cc1)C(=O)NC2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J10 compound treatment 841440.0 -172000.0 -0.84 940160.0 -49500.0 -0.29 744670.0 -207767.741935484 -1.18998816730121 -1.3417 -0.903 2071551 Maybridge1_004254 Cc1ccc(CSc2ssc(=S)c2c3ccccc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J11 compound treatment 1088560.0 75200.0 0.37 1088320.0 98700.0 0.59 1290570.0 338132.258064516 1.93664994542107 1.6692 0.8116 2071552 Maybridge1_004255 COC(=O)C1(C)CCC(C(=O)O)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J12 compound treatment 836010.0 -177000.0 -0.87 926280.0 -63300.0 -0.38 860800.0 -91637.741935484 -0.524854472429555 -1.0207 -0.9445 2071553 Maybridge1_004256 Oc1ccc(Br)cc1/C=N/N2C(=O)c3ccccc3C2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J13 compound treatment 1043210.0 29900.0 0.15 1051580.0 62000.0 0.37 1123700.0 171262.258064516 0.980903285098729 0.8633 0.8161 1396701 Maybridge1_004257 COc1ccc(CCNC(=O)c2ccc(Cl)cc2Cl)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J14 compound treatment 966080.0 -47200.0 -0.23 863050.0 -127000.0 -0.75 945050.0 -7387.74193548399 -0.04231323594512 -0.5923 -0.7512 1397018 Maybridge1_004258 Fc1ccc(cc1Cl)S(=O)(=O)NCc2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J15 compound treatment 914740.0 -98600.0 -0.48 972960.0 -16700.0 -0.1 827840.0 -124597.741935484 -0.713632622631655 -0.7473 -0.8623 2071554 Maybridge1_004259 CCOC(=O)/C(=N/Nc1cccc(c1)[N+](=O)[O-])/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J16 compound treatment 477180.0 -536000.0 -2.62 494320.0 -495000.0 -2.95 515380.0 -437057.741935484 -2.50324490455363 -4.6581 -0.9976 2071555 Maybridge1_004260 CCOC(=O)C(C#N)C1C(=C(N)Oc2c(OC)cc(Br)cc12)C(=O)OCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J17 compound treatment 879570.0 -134000.0 -0.65 1101860.0 112000.0 0.67 907740.0 -44697.741935484 -0.256005978179354 -0.1398 -0.1443 2071556 Maybridge1_004261 Cn1c2CCC/C(=N\OC(=O)c3cccc4ccccc34)/c2c5ccccc15 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J18 compound treatment 882160.0 -131000.0 -0.64 980020.0 -9610.0 -0.06 816800.0 -135637.741935484 -0.776864138961485 -0.8515 -0.8442 1598126 Maybridge1_004262 COC(=O)c1ccc(n1C)S(=O)(=O)NCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J19 compound treatment 1003740.0 -9580.0 -0.05 1156760.0 167000.0 0.99 968060.0 15622.258064516 0.0894763646662372 0.5984 0.599 1546260 Maybridge1_004263 CC1(C)C(NC(=O)c2c(Cl)cccc2Cl)[C@]3(C)CCC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J20 compound treatment 948910.0 -64400.0 -0.31 1023630.0 34000.0 0.2 932960.0 -19477.741935484 -0.111558619317189 -0.1294 -0.3314 1367531 Maybridge1_004264 Clc1ccc2nc(sc2c1)N3CCN(CC3)S(=O)(=O)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J21 compound treatment 212800.0 -801000.0 -3.91 450880.0 -539000.0 -3.2 353130.0 -599307.741935484 -3.43253054989012 -6.0896 -0.9965 1298924 Maybridge1_004265 CC1(C)C2CCC1(C)C(C2)N3CCN(Cc4ccccc4)CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J22 compound treatment 769980.0 -243000.0 -1.19 868810.0 -121000.0 -0.72 960680.0 8242.25806451601 0.0472074705979271 -1.074 -0.7727 2071557 Maybridge1_004266 Oc1ccc(cc1)n2nnnc2SCc3cc(F)cc(F)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J23 compound treatment 902830.0 -110000.0 -0.54 852900.0 -137000.0 -0.81 1041730.0 89292.258064516 0.511420731334585 -0.4858 -0.4409 2071558 Maybridge1_004267 Fc1ccc(cc1)C(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 J24 compound treatment 568040.0 -445000.0 -2.18 712160.0 -277000.0 -1.65 655790.0 -296647.741935484 -1.69904769369571 -3.1896 -0.9918 2071559 Maybridge1_004268 Oc1ccc(cc1)n2nnnc2SCC(=O)c3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K01 mock treatment 1055560.0 42200.0 0.21 969550.0 -20100.0 -0.12 1069440.0 117002.258064516 0.670129546325489 0.4371 0.6145 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K02 mock treatment 1077930.0 64600.0 0.32 950090.0 -39500.0 -0.24 994260.0 41822.258064516 0.239536666101159 0.1848 0.4011 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K03 compound treatment 1069830.0 56500.0 0.28 904250.0 -85400.0 -0.51 975210.0 22772.258064516 0.130427935477676 -0.0584 -0.0986 2071560 Maybridge1_004269 CCOC(=O)/C(=N/Nc1cc(n[nH]1)c2ccccc2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K04 compound treatment 770440.0 -243000.0 -1.19 756960.0 -233000.0 -1.38 705640.0 -246797.741935484 -1.41353219649988 -2.3 -0.9971 2071561 Maybridge1_004270 Cc1nc(COc2ccc(cc2)/C(=N/O)/N)cs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K05 compound treatment 1126490.0 113000.0 0.55 952540.0 -37100.0 -0.22 902020.0 -50417.741935484 -0.288767234828505 0.0252 0.038 1493954 Maybridge1_004271 Cc1cc(=O)n2nc(cc2[nH]1)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K06 compound treatment 1097600.0 84300.0 0.41 988920.0 -708.0 0.0 1184710.0 232272.258064516 1.33033759771493 1.0034 0.7205 1671220 Maybridge1_004272 CC(C)(Oc1ccc2ccccc2c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K07 compound treatment 1107890.0 94600.0 0.46 867850.0 -122000.0 -0.72 1048880.0 96442.258064516 0.552372302146024 0.1676 0.1641 1588381 Maybridge1_004273 Clc1ccc(cc1)S(=O)(=O)CCN2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K08 compound treatment 943310.0 -70000.0 -0.34 956880.0 -32700.0 -0.19 880910.0 -71527.741935484 -0.40967459983962 -0.5465 -0.9618 2071562 Maybridge1_004274 CSc1nc(O)nc(n1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K09 compound treatment 577240.0 -436000.0 -2.13 535200.0 -454000.0 -2.7 572550.0 -379887.741935484 -2.17580416283476 -4.0465 -0.9939 2071563 Maybridge1_004275 CCOc1cc(/C=N/C(=C(\N)/C#N)/C#N)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K10 compound treatment 973980.0 -39300.0 -0.19 890770.0 -98900.0 -0.59 860130.0 -92307.741935484 -0.528691892351745 -0.7556 -0.9287 1542810 Maybridge1_004276 CCc1nc(O)cc2cc(OC)c(OC)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K11 compound treatment 1047240.0 33900.0 0.17 999680.0 10100.0 0.06 1250250.0 297812.258064516 1.70571745099909 1.115 0.6502 2071564 Maybridge1_004277 OCc1ccccc1C(=O)N/N=C/c2ccc(O)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K12 compound treatment 872800.0 -141000.0 -0.69 821540.0 -168000.0 -1.0 1005620.0 53182.258064516 0.304600980005767 -0.7976 -0.6379 2071565 Maybridge1_004278 Brc1ccc(cc1)C(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K13 compound treatment 934890.0 -78400.0 -0.38 967550.0 -22100.0 -0.13 822960.0 -129477.741935484 -0.741582785647015 -0.7252 -0.8582 2071566 Maybridge1_004279 [O-][N+](=O)c1ccc(cc1)C(=O)c2ccc3CCCc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K14 compound treatment 818640.0 -195000.0 -0.95 720480.0 -269000.0 -1.6 812400.0 -140037.741935484 -0.802065105614678 -1.9363 -0.9551 2071567 Maybridge1_004280 OC1(Cc2ccccc2C3=NCCN31)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K15 compound treatment 946560.0 -66800.0 -0.33 974590.0 -15000.0 -0.09 939040.0 -13397.741935484 -0.0767354653964132 -0.2843 -0.8196 2071568 Maybridge1_004281 COc1cc(cc(OC)c1OC)C(=O)Nc2ccccc2SCCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K16 compound treatment 871810.0 -142000.0 -0.69 1062010.0 72400.0 0.43 925060.0 -27377.741935484 -0.156805809444513 -0.2412 -0.2908 2071569 Maybridge1_004282 C1CN(CCN1)c2ncccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K17 compound treatment 828500.0 -185000.0 -0.9 1013560.0 23900.0 0.14 853640.0 -98797.741935484 -0.565863318165205 -0.7659 -0.7124 2071570 Maybridge1_004283 CC(=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K18 compound treatment 786190.0 -227000.0 -1.11 817570.0 -172000.0 -1.02 944800.0 -7637.74193548399 -0.043745109050415 -1.2567 -0.8322 2071571 Maybridge1_004284 Oc1ccccc1/C=N/CC\N=C\c2ccccc2O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K19 compound treatment 663610.0 -350000.0 -1.71 822910.0 -167000.0 -0.99 674930.0 -277507.741935484 -1.58942348875432 -2.4765 -0.9768 2071572 Maybridge1_004285 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Cl)ccc3O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K20 compound treatment 825170.0 -188000.0 -0.92 881920.0 -108000.0 -0.64 872560.0 -79877.741935484 -0.457499161556475 -1.1647 -0.9624 2071573 Maybridge1_004286 Cc1ccc(cc1C)C(=O)c2c(C)ccc3ccccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K21 compound treatment 923680.0 -89600.0 -0.44 997600.0 7970.0 0.05 911890.0 -40547.741935484 -0.232236884631456 -0.3596 -0.722 2071574 Maybridge1_004287 CCOC(=O)CSc1cc(OC)c(cc1OC)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K22 compound treatment 829150.0 -184000.0 -0.9 855360.0 -134000.0 -0.8 855800.0 -96637.741935484 -0.553491934535456 -1.3001 -0.9818 2071575 Maybridge1_004288 CCCCSc1nnc(S)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K23 compound treatment 831470.0 -182000.0 -0.89 916450.0 -73200.0 -0.44 996400.0 43962.258064516 0.251793499882485 -0.6188 -0.6062 2071576 Maybridge1_004289 CC(=O)c1ccc(Sc2ccccc2N)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 K24 compound treatment 863080.0 -150000.0 -0.73 997200.0 7570.0 0.05 1024210.0 71772.258064516 0.411075064115507 -0.1605 -0.1905 2071577 Maybridge1_004290 CCC(C)C(NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)NC(C(C)C)C(=O)NC(CCCCNC(=O)OC(C)(C)C)C(=O)NC(CCC(=O)OC(C)(C)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L01 mock treatment 972740.0 -40600.0 -0.2 925030.0 -64600.0 -0.38 902770.0 -49667.741935484 -0.28447161551262 -0.5005 -0.9672 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L02 mock treatment 1019200.0 5880.0 0.03 966270.0 -23400.0 -0.14 1058490.0 106052.258064516 0.607413504313566 0.2871 0.4602 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L03 compound treatment 1154190.0 141000.0 0.69 849990.0 -140000.0 -0.83 1013140.0 60702.258064516 0.347671723013042 0.1187 0.1047 2071578 Maybridge1_004291 Cc1ccc(cc1)S(=O)(=O)OCC(NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L04 compound treatment 610150.0 -403000.0 -1.97 640320.0 -349000.0 -2.08 567300.0 -385137.741935484 -2.20587349804595 -3.6101 -0.9989 1026962 Maybridge1_004292 COc1cc(cc(OC)c1OC)C(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L05 compound treatment 667200.0 -346000.0 -1.69 743400.0 -246000.0 -1.46 729240.0 -223197.741935484 -1.27836337536003 -2.5598 -0.9935 2071579 Maybridge1_004293 O=C(O/N=C/c1ccc2OCOc2c1)C3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L06 compound treatment 1015930.0 2610.0 0.01 926990.0 -62600.0 -0.37 940320.0 -12117.741935484 -0.0694042750973025 -0.2478 -0.6536 2071580 Maybridge1_004294 CC(=O)OC[C@H]1O[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1O[C@@H]2O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L07 compound treatment 786190.0 -227000.0 -1.11 658680.0 -331000.0 -1.97 809030.0 -143407.741935484 -0.821366755074055 -2.2511 -0.9364 2071581 Maybridge1_004295 O=C(O/N=C/c1ccc2OCOc2c1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L08 compound treatment 1136360.0 123000.0 0.6 971840.0 -17800.0 -0.11 1095860.0 143422.258064516 0.821449896093071 0.7603 0.7429 2071582 Maybridge1_004296 CCSC(SCC)[C@H](O)[C@@H](O)[C@H](O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L09 compound treatment 1083720.0 70400.0 0.34 993860.0 4230.0 0.03 994560.0 42122.258064516 0.241254913827513 0.3524 0.8373 1408083 Maybridge1_004297 Clc1ccc(C(=O)N2CCC(CC2)NC(=O)C3CCCCC3)c(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L10 compound treatment 47230.0 -966000.0 -4.72 43420.0 -946000.0 -5.63 38410.0 -914027.741935484 -5.23508696468397 -8.9962 -0.9975 2071583 Maybridge1_004298 Cc1ccc(cc1)/C(=C/2\C=C(\Cl)/C(=N/O)/C=C2/Cl)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L11 compound treatment 1172320.0 159000.0 0.78 976640.0 -13000.0 -0.08 1141950.0 189512.258064516 1.08543002178527 1.0306 0.7708 2071584 Maybridge1_004299 COC(=O)C1CCC(C)(C(=O)O)C1(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L12 compound treatment 941140.0 -72200.0 -0.35 1031490.0 41900.0 0.25 937350.0 -15087.741935484 -0.0864149275882077 -0.1098 -0.2494 1570985 Maybridge1_004300 CC(=O)Nc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L13 compound treatment 1224610.0 211000.0 1.03 983210.0 -6420.0 -0.04 1354190.0 401752.258064516 2.30103301325656 1.9025 0.7543 1533685 Maybridge1_004301 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OC)c(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L14 compound treatment 847060.0 -166000.0 -0.81 990320.0 693.0 0.0 802730.0 -149707.741935484 -0.857449957327491 -0.9617 -0.8142 2071585 Maybridge1_004302 Cn1c(Sc2nc3ccc(Cl)cc3s2)nnc1c4ccc(Cl)cc4Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L15 compound treatment 1084520.0 71200.0 0.35 1004640.0 15000.0 0.09 1204320.0 251882.258064516 1.44265372409428 1.0853 0.73 1713236 Maybridge1_004303 CC(=O)NCc1ccc(cc1)S(=O)(=O)NN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L16 compound treatment 809760.0 -204000.0 -0.99 951600.0 -38000.0 -0.23 799050.0 -153387.741935484 -0.878527129437434 -1.212 -0.9003 1467188 Maybridge1_004304 CCOC(=O)c1cc(NC(=O)Nc2ccc(C)c(Cl)c2)ccc1N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L17 compound treatment 772340.0 -241000.0 -1.18 945440.0 -44200.0 -0.26 844380.0 -108057.741935484 -0.618899897985334 -1.1888 -0.8768 2071586 Maybridge1_004305 FC(F)(F)c1cccc(c1)C(=O)O/N=C/2\CCCc3[nH]c4ccccc4c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L18 compound treatment 950400.0 -62900.0 -0.31 1056110.0 66500.0 0.4 1125150.0 172712.258064516 0.98920814910944 0.6219 0.5609 1376744 Maybridge1_004306 Cc1cc(C)c(C#N)c(OCC(=O)Nc2ccc(Oc3ccccc3)cc2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L19 compound treatment 972190.0 -41100.0 -0.2 1192650.0 203000.0 1.21 961310.0 8872.25806451601 0.0508157908232706 0.6103 0.4983 1402584 Maybridge1_004307 CC1(C)C(NC(=O)c2ccc(Cl)cc2Cl)[C@]3(C)CCC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L20 compound treatment 823860.0 -189000.0 -0.93 925960.0 -63700.0 -0.38 863140.0 -89297.741935484 -0.511452140163993 -1.0483 -0.9332 1196364 Maybridge1_004308 OC(=O)C1CCC1C(=O)N2CCN(CC2)c3nc4ccc(Cl)cc4s3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L21 compound treatment 871550.0 -142000.0 -0.69 1013860.0 24200.0 0.14 951250.0 -1187.74193548399 -0.00680278293380252 -0.3207 -0.4532 2071587 Maybridge1_004309 COc1ccc(CC2CCC(=O)CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L22 compound treatment 942470.0 -70900.0 -0.35 1107240.0 118000.0 0.7 989520.0 37082.258064516 0.212388352024765 0.3266 0.4038 2071588 Maybridge1_004310 COC(=O)Cc1nc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)sc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L23 compound treatment 653120.0 -360000.0 -1.76 902010.0 -87600.0 -0.52 815780.0 -136657.741935484 -0.782706181231089 -1.7688 -0.8865 1044240 Maybridge1_004311 Brc1ccc2[nH]c3ccccc3c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 L24 compound treatment 961250.0 -52100.0 -0.25 916840.0 -72800.0 -0.43 1062440.0 110002.258064516 0.630037099377228 -0.033 -0.041 1291967 Maybridge1_004312 OC(COc1ccc(F)cc1)CN2CCN(CC2)C(c3ccccc3)c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M01 mock treatment 1067850.0 54500.0 0.27 1032030.0 42400.0 0.25 1054820.0 102382.258064516 0.586393607127834 0.6379 0.9223 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M02 mock treatment 1016700.0 3380.0 0.02 974560.0 -15100.0 -0.09 1227560.0 275122.258064516 1.57576064796251 0.8676 0.5496 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M03 compound treatment 763400.0 -250000.0 -1.22 699280.0 -290000.0 -1.73 720090.0 -232347.741935484 -1.33076993101383 -2.4701 -0.9886 1140868 Maybridge1_004313 Nc1cc(nn1c2ccccc2)C3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M04 compound treatment 913080.0 -100000.0 -0.49 748000.0 -242000.0 -1.44 813790.0 -138647.741935484 -0.794103891149237 -1.5708 -0.9169 1497141 Maybridge1_004314 Cc1c(Cl)c(O)nc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M05 compound treatment 1176960.0 164000.0 0.8 962330.0 -27300.0 -0.16 1120120.0 167682.258064516 0.960398862230903 0.9224 0.732 2071589 Maybridge1_004315 FC(F)(F)c1cc(=O)n([nH]1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M06 compound treatment 364000.0 -649000.0 -3.17 415690.0 -574000.0 -3.41 352930.0 -599507.741935484 -3.43367604837436 -5.7845 -0.9994 2071590 Maybridge1_004316 CC1(C)N=C(N)N=C(N)N1c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M07 compound treatment 887000.0 -126000.0 -0.62 746990.0 -243000.0 -1.44 754110.0 -198327.741935484 -1.13592063884527 -1.8452 -0.9525 1701903 Maybridge1_004317 Clc1ccc(cc1)S(=O)(=O)CCN2CCSCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M08 compound treatment 1117920.0 105000.0 0.51 1022480.0 32900.0 0.2 993570.0 41132.258064516 0.235584696330545 0.5439 0.913 1496378 Maybridge1_004318 Clc1ccc(cc1)c2nc(=O)[nH]c(=S)[nH]2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M09 compound treatment 1123940.0 111000.0 0.54 900120.0 -89500.0 -0.53 1069520.0 117082.258064516 0.670587745719184 0.3919 0.3871 1369556 Maybridge1_004319 Cc1nn(C)c(NC(=O)c2ccc(Cl)cc2Cl)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M10 compound treatment 940090.0 -73200.0 -0.36 952540.0 -37100.0 -0.22 967780.0 15342.258064516 0.0878726667883067 -0.2832 -0.6595 1006055 Maybridge1_004320 CCCCCCCCCCCCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M11 compound treatment 916520.0 -96800.0 -0.47 1047790.0 58200.0 0.35 1174460.0 222022.258064516 1.27163080039784 0.6608 0.472 2071591 Maybridge1_004321 OCc1ccccc1C(=O)N/N=C/c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M12 compound treatment 1078400.0 65100.0 0.32 954790.0 -34800.0 -0.21 1102510.0 150072.258064516 0.859537720693919 0.5602 0.5962 1049047 Maybridge1_004322 [O-][N+](=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M13 compound treatment 968640.0 -44700.0 -0.22 1034880.0 45300.0 0.27 949450.0 -2987.74193548399 -0.0171122692919269 0.0194 0.056 2071592 Maybridge1_004323 Cc1onc(c1C(=O)N2CCC(CCCC3CCN(CC3)C(=O)c4c(C)onc4c5c(Cl)cccc5Cl)CC2)c6c(Cl)cccc6Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M14 compound treatment 1114140.0 101000.0 0.49 930340.0 -59300.0 -0.35 1258780.0 306342.258064516 1.75457296135175 1.0938 0.5893 2071593 Maybridge1_004324 CCC[C@H]1[C@@H](Cc2cncn2C)COC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M15 compound treatment 882750.0 -131000.0 -0.64 1030260.0 40600.0 0.24 843640.0 -108797.741935484 -0.623138242377007 -0.5886 -0.637 2071594 Maybridge1_004325 Clc1c(sc2ccccc12)C(=O)Nc3ccccc3SCCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M16 compound treatment 1073860.0 60500.0 0.3 1020050.0 30400.0 0.18 1046670.0 94232.258064516 0.539714543895215 0.5868 0.9148 2071595 Maybridge1_004326 N[C@@H](C(=O)O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M17 compound treatment 1082850.0 69500.0 0.34 1175450.0 186000.0 1.11 971250.0 18812.258064516 0.107747065489802 0.8963 0.772 1313557 Maybridge1_004327 CCOC(=O)c1ccc(N2CCCCC2)c(NS(=O)(=O)c3cc(Cl)c(Cl)cc3Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M18 compound treatment 979390.0 -33900.0 -0.17 946750.0 -42900.0 -0.25 989660.0 37222.258064516 0.21319020096373 -0.1198 -0.3227 1011577 Maybridge1_004328 Cc1ccc2cc(C)c(C)cc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M19 compound treatment 582260.0 -431000.0 -2.11 681140.0 -308000.0 -1.83 659360.0 -293077.741935484 -1.6786005457521 -3.2442 -0.9956 2071596 Maybridge1_004329 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Br)cc(Br)c3O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M20 compound treatment 912640.0 -101000.0 -0.49 969130.0 -20500.0 -0.12 913390.0 -39047.741935484 -0.223645645999686 -0.4835 -0.8728 1686247 Maybridge1_004330 CC(=O)Oc1cc(OC(=O)C)cc(c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M21 compound treatment 958900.0 -54400.0 -0.27 1021350.0 31700.0 0.19 901790.0 -50647.741935484 -0.290084558085377 -0.2121 -0.486 2071597 Maybridge1_004331 [O-][N+](=O)c1cc(Cl)c(Sc2ccccc2)cc1Sc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M22 compound treatment 1022430.0 9110.0 0.04 1007920.0 18300.0 0.11 899200.0 -53237.741935484 -0.304918763456234 -0.0876 -0.2679 2071598 Maybridge1_004332 Sc1nc(c([nH]1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M23 compound treatment 553190.0 -460000.0 -2.25 643210.0 -346000.0 -2.06 605090.0 -347347.741935484 -1.98943155944955 -3.6359 -0.9986 2071599 Maybridge1_004333 Nc1ccccc1SCc2c(Cl)cccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 M24 compound treatment 789760.0 -224000.0 -1.09 896000.0 -93600.0 -0.56 986820.0 34382.258064516 0.196924122487578 -0.8384 -0.6752 2071600 Maybridge1_004334 CCCCCCSc1nnc(S)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N01 mock treatment 970080.0 -43200.0 -0.21 1046080.0 56500.0 0.34 874090.0 -78347.741935484 -0.448736098152069 -0.1872 -0.3126 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N02 mock treatment 1078980.0 65700.0 0.32 949860.0 -39800.0 -0.24 935900.0 -16537.741935484 -0.0947197915989191 -0.006 -0.0147 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N03 compound treatment 1044250.0 30900.0 0.15 869500.0 -120000.0 -0.71 1073180.0 120742.258064516 0.691550367980703 0.0741 0.0737 2071601 Maybridge1_004335 COC(=O)C(NC(=O)OCc1ccccc1)C(C)OS(=O)(=O)c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N04 compound treatment 1111000.0 97700.0 0.48 960060.0 -29600.0 -0.18 1077570.0 125132.258064516 0.716694059709684 0.5878 0.6689 931 Maybridge1_004336 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N05 compound treatment 994580.0 -18700.0 -0.09 807800.0 -182000.0 -1.08 961350.0 8912.25806451601 0.0510448905201178 -0.6477 -0.5962 2071602 Maybridge1_004337 COc1ccccc1CC(=O)O/N=C/c2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N06 compound treatment 1004480.0 -8840.0 -0.04 957220.0 -32400.0 -0.19 957510.0 5072.25806451601 0.0290513196227857 -0.1194 -0.5983 2071603 Maybridge1_004338 CC(=O)OC[C@H]1O[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1O[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N07 compound treatment 1159910.0 147000.0 0.72 1017440.0 27800.0 0.17 1083930.0 131492.258064516 0.753120911508391 0.9438 0.8968 1654475 Maybridge1_004339 Cc1ccc(cc1)C(=O)N2CCN(Cc3ccccc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N08 compound treatment 1264430.0 251000.0 1.23 1003780.0 14200.0 0.08 1059160.0 106722.258064516 0.611250924235756 1.1098 0.8082 2071604 Maybridge1_004340 COCC1(C)OC(=O)C(=C1C)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N09 compound treatment 1078820.0 65500.0 0.32 1001830.0 12200.0 0.07 1049970.0 97532.258064516 0.55861526888511 0.5492 0.8477 1437551 Maybridge1_004341 O=C(NC1CCN(CC1)C(=O)c2ccco2)C3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N10 compound treatment 82680.0 -931000.0 -4.55 206730.0 -783000.0 -4.66 301870.0 -650567.741935484 -3.72612181139982 -7.4643 -0.9954 2071605 Maybridge1_004342 Cc1ccc(cc1)/C(=C/2\C=C/C(=N\O)/C(=C2/Cl)/Cl)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N11 compound treatment 935290.0 -78000.0 -0.38 952160.0 -37500.0 -0.22 1004180.0 51742.258064516 0.296353390919267 -0.1777 -0.3341 2071606 Maybridge1_004343 CC(C)(C)c1cc(n[nH]1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N12 compound treatment 559370.0 -454000.0 -2.22 559390.0 -430000.0 -2.56 607320.0 -345117.741935484 -1.97665925135032 -3.8989 -0.9944 1478375 Maybridge1_004344 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3c(C)onc3c4ccccc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N13 compound treatment 1104680.0 91400.0 0.45 1082680.0 93100.0 0.55 1182880.0 230442.258064516 1.31985628658417 1.3392 0.8933 1075430 Maybridge1_004345 OCC(NC(=O)C(Cl)Cl)C(O)c1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N14 compound treatment 813350.0 -200000.0 -0.98 897550.0 -92100.0 -0.55 911550.0 -40887.741935484 -0.234184232054658 -1.0154 -0.8874 2071607 Maybridge1_004346 Cn1c(Sc2nc3ccc(Cl)cc3s2)nnc1c4ccc5ncccc5c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N15 compound treatment 903940.0 -109000.0 -0.53 906720.0 -82900.0 -0.49 951120.0 -1317.74193548399 -0.00754735694855595 -0.5976 -0.8218 1510250 Maybridge1_004347 COc1ccccc1N2CCN(CC2)C(=O)Nc3ccc(Br)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N16 compound treatment 41480.0 -972000.0 -4.75 54450.0 -935000.0 -5.56 36390.0 -916047.741935484 -5.24665649937475 -8.9813 -0.9979 2071608 Maybridge1_004348 COCc1cc(O)nc(SC2CC(=O)N(C2=O)c3ccc(cc3)N4CCOCC4)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N17 compound treatment 939300.0 -74000.0 -0.36 982300.0 -7330.0 -0.04 980960.0 28522.258064516 0.163361016899462 -0.1396 -0.3498 2071609 Maybridge1_004349 Cn1c2CCC/C(=N\OC(=O)c3ccc(Cl)cc3)/c2c4ccccc14 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N18 compound treatment 1028160.0 14800.0 0.07 1054240.0 64600.0 0.38 978750.0 26312.258064516 0.150703258648654 0.3507 0.8369 1382314 Maybridge1_004350 Cc1nnsc1C(=O)NCc2ccc3OCOc3c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N19 compound treatment 498200.0 -515000.0 -2.52 564870.0 -425000.0 -2.53 476600.0 -475837.741935484 -2.725357060647 -4.4849 -0.9993 1354484 Maybridge1_004351 CC1(C)C(NS(=O)(=O)c2ccc(Cl)cc2)[C@]3(C)CCC1C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N20 compound treatment 928010.0 -85300.0 -0.42 1086800.0 97200.0 0.58 957220.0 4782.25806451601 0.0273903468206435 0.1088 0.1526 1437585 Maybridge1_004352 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N21 compound treatment 1032000.0 18700.0 0.09 999490.0 9860.0 0.06 1022580.0 70142.258064516 0.401739251468983 0.3185 0.7654 2071610 Maybridge1_004353 Brc1cnc(nc1)N2CCN(CC2)C(c3ccccc3)(c4ccccc4)c5ccccc5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N22 compound treatment 870510.0 -143000.0 -0.7 1010740.0 21100.0 0.13 1027240.0 74802.258064516 0.428429366151683 -0.083 -0.1002 2071611 Maybridge1_004354 COC(=O)Cc1nc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)sc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N23 compound treatment 961190.0 -52100.0 -0.25 1036810.0 47200.0 0.28 1179270.0 226832.258064516 1.29918003894371 0.765 0.5653 1983514 Maybridge1_004355 O/N=C/C(=O)Nc1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 N24 compound treatment 978990.0 -34300.0 -0.17 973460.0 -16200.0 -0.1 930630.0 -21807.741935484 -0.124903676658539 -0.2245 -0.9752 2071612 Maybridge1_004356 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3nc(no3)c4ccc(cc4)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O01 mock treatment 935210.0 -78100.0 -0.38 901800.0 -87800.0 -0.52 993320.0 40882.258064516 0.23415282322525 -0.3867 -0.5621 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O02 mock treatment 1110820.0 97500.0 0.48 1123360.0 134000.0 0.8 1057220.0 104782.258064516 0.600139588938667 1.0806 0.9786 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O03 compound treatment 1103150.0 89800.0 0.44 908840.0 -80800.0 -0.48 1114890.0 162452.258064516 0.930444076868131 0.5132 0.452 1044275 Maybridge1_004357 CS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O04 compound treatment 977840.0 -35500.0 -0.17 975710.0 -13900.0 -0.08 898950.0 -53487.741935484 -0.306350636561529 -0.3247 -0.8981 2071613 Maybridge1_004358 CCCc1cc(O)nc(SCc2ccc(Cl)cc2Cl)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O05 compound treatment 1006810.0 -6510.0 -0.03 996100.0 6470.0 0.04 1042240.0 89802.258064516 0.514341752469387 0.3008 0.5821 1596267 Maybridge1_004359 CCN(CCS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O06 compound treatment 972190.0 -41100.0 -0.2 896170.0 -93500.0 -0.56 857410.0 -95027.741935484 -0.544270671737356 -0.7511 -0.9349 1044282 Maybridge1_004360 Clc1ccc(NC(=N)NC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O07 compound treatment 1117220.0 104000.0 0.51 967840.0 -21800.0 -0.13 1165440.0 213002.258064516 1.21996881875879 0.9226 0.6949 2071614 Maybridge1_004361 Nc1cc(n[nH]1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O08 compound treatment 961280.0 -52000.0 -0.25 972450.0 -17200.0 -0.1 943110.0 -9327.74193548399 -0.0534245712422096 -0.2366 -0.8476 2071615 Maybridge1_004362 CSc1nc(O)nc(n1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O09 compound treatment 944160.0 -69200.0 -0.34 929180.0 -60400.0 -0.36 918360.0 -34077.741935484 -0.19518000866642 -0.5153 -0.9713 2071616 Maybridge1_004363 Cc1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)n(C)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O10 compound treatment 951490.0 -61800.0 -0.3 994800.0 5170.0 0.03 1152500.0 200062.258064516 1.14585506682872 0.5049 0.4259 2071617 Maybridge1_004364 COC(=O)c1c(N)cccc1F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O11 compound treatment 921440.0 -91900.0 -0.45 865410.0 -124000.0 -0.74 902730.0 -49707.741935484 -0.284700715209467 -0.85 -0.934 2071618 Maybridge1_004365 OCc1ccccc1C(=O)N/N=C/C=C/c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O12 compound treatment 1022950.0 9630.0 0.05 976760.0 -12900.0 -0.08 1000960.0 48522.258064516 0.277910865323067 0.1434 0.4911 2071619 Maybridge1_004366 Oc1ccccc1/C=N/CC2CCC(C\N=C\c3ccccc3O)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O13 compound treatment 913240.0 -100000.0 -0.49 1075840.0 86200.0 0.51 888550.0 -63887.741935484 -0.365916557741803 -0.1976 -0.2478 2071620 Maybridge1_004367 CC(C)N(CCC#N)C(=S)Nc1ccc(F)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O14 compound treatment 875200.0 -138000.0 -0.67 756740.0 -233000.0 -1.38 791360.0 -161077.741935484 -0.92257154615631 -1.7218 -0.9589 1340247 Maybridge1_004368 Cc1nc2ccccc2c(C(=O)O)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O15 compound treatment 659110.0 -354000.0 -1.73 675590.0 -314000.0 -1.87 611620.0 -340817.741935484 -1.95203103393924 -3.2044 -0.9988 2071621 Maybridge1_004369 COc1cccc(/C=N/c2ccccc2SCCC#N)c1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O16 compound treatment 709160.0 -304000.0 -1.49 763700.0 -226000.0 -1.34 701300.0 -251137.741935484 -1.4383895136078 -2.4641 -0.9991 1015426 Maybridge1_004370 Cc1ccc(NC(=O)c2ccccc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O17 compound treatment 986820.0 -26500.0 -0.13 1028120.0 38500.0 0.23 900910.0 -51527.741935484 -0.295124751416015 -0.113 -0.2859 1558027 Maybridge1_004371 CCOC(=O)c1ccc(N2CCOCC2)c(NC(=O)c3ccc(Cl)c(Cl)c3)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O18 compound treatment 1000420.0 -12900.0 -0.06 963320.0 -26300.0 -0.16 976980.0 24542.258064516 0.140565597063165 -0.0456 -0.2075 2071622 Maybridge1_004372 Cc1ccc(C#Cc2ccc(C)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O19 compound treatment 749170.0 -264000.0 -1.29 892910.0 -96700.0 -0.58 742430.0 -210007.741935484 -1.20281775032466 -1.7716 -0.9548 2071623 Maybridge1_004373 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Cl)cc(Cl)c3O)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O20 compound treatment 1049330.0 36000.0 0.18 988400.0 -1230.0 -0.01 949290.0 -3147.74193548399 -0.0180286680793158 0.0869 0.4912 2071624 Maybridge1_004374 CC(OCc1ccccc1)C(NC(=O)OC(C)(C)C)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O21 compound treatment 770300.0 -243000.0 -1.19 822990.0 -167000.0 -0.99 800570.0 -151867.741935484 -0.86982134095724 -1.7598 -0.9918 2071625 Maybridge1_004375 Nc1ccccc1Sc2cc(Sc3ccccc3N)c(cc2Cl)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O22 compound treatment 672370.0 -341000.0 -1.67 753290.0 -236000.0 -1.41 785550.0 -166887.741935484 -0.955848277123367 -2.325 -0.977 2071626 Maybridge1_004376 CCCSc1nnc(S)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O23 compound treatment 732000.0 -281000.0 -1.37 819330.0 -170000.0 -1.01 788840.0 -163597.741935484 -0.937004827057684 -1.9192 -0.9855 1022261 Maybridge1_004377 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 O24 compound treatment 860490.0 -153000.0 -0.75 902940.0 -86700.0 -0.52 900890.0 -51547.741935484 -0.295239301264439 -0.8992 -0.9424 1577497 Maybridge1_004378 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P01 mock treatment 959480.0 -53800.0 -0.26 866420.0 -123000.0 -0.73 832960.0 -119477.741935484 -0.684307861435212 -0.97 -0.9358 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P02 mock treatment 1094260.0 80900.0 0.4 1115300.0 126000.0 0.75 876360.0 -76077.741935484 -0.43573469035599 0.4082 0.4292 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P03 compound treatment 902720.0 -111000.0 -0.54 835040.0 -155000.0 -0.92 800120.0 -152317.741935484 -0.872398712546771 -1.3464 -0.9773 2071627 Maybridge1_004379 COc1cccc2C(=O)COc21 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P04 compound treatment 640250.0 -373000.0 -1.82 517230.0 -472000.0 -2.81 547870.0 -404567.741935484 -2.31715867578948 -4.012 -0.9852 1045862 Maybridge1_004380 c1c(nc2ccccn12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P05 compound treatment 1031680.0 18400.0 0.09 1163360.0 174000.0 1.03 1137410.0 184972.258064516 1.05942720619311 1.2599 0.8499 2071628 Maybridge1_004381 O=C(O/N=C/c1ccc2OCOc2c1)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P06 compound treatment 1102720.0 89400.0 0.44 1000750.0 11100.0 0.07 1081840.0 129402.258064516 0.741150452348124 0.7183 0.8325 2071629 Maybridge1_004382 CC1(C)O[C@H]2CO[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P07 compound treatment 1020750.0 7430.0 0.04 987150.0 -2480.0 -0.01 1086210.0 133772.258064516 0.766179594228682 0.4548 0.5928 1133999 Maybridge1_004383 Clc1cccc(Cl)c1C(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P08 compound treatment 838150.0 -175000.0 -0.86 766040.0 -224000.0 -1.33 844860.0 -107577.741935484 -0.616150701623167 -1.6175 -0.9531 2071630 Maybridge1_004384 C1=CC=CC(C=C1)C2C=CC=CC=C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P09 compound treatment 1138110.0 125000.0 0.61 1147040.0 157000.0 0.94 1070180.0 117742.258064516 0.674367890717163 1.2818 0.9823 1014809 Maybridge1_004385 O=C1NC(=O)C2(CCCCC2)N1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P10 compound treatment 1076580.0 63300.0 0.31 974050.0 -15600.0 -0.09 1052550.0 100112.258064516 0.573392199331755 0.456 0.6931 1454866 Maybridge1_004386 COc1cc(cc(OC)c1OC)c2cc(C(=O)O)c3ccc(C)cc3n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P11 compound treatment 612500.0 -401000.0 -1.96 636860.0 -353000.0 -2.1 671130.0 -281307.741935484 -1.61118795995481 -3.272 -0.9942 2071631 Maybridge1_004387 Nc1ccc2nonc2c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P12 compound treatment 918030.0 -95300.0 -0.47 1035260.0 45600.0 0.27 964480.0 12042.258064516 0.068971941798412 -0.0723 -0.1331 2071632 Maybridge1_004388 OC(=O)c1cccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P13 compound treatment 1072170.0 58800.0 0.29 1106350.0 117000.0 0.69 1052750.0 100312.258064516 0.574537697815991 0.8984 0.9499 2431 Maybridge1_004389 CCN(CC)CCNC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P14 compound treatment 573060.0 -440000.0 -2.15 589760.0 -400000.0 -2.38 620430.0 -332007.741935484 -1.90157182570865 -3.7126 -0.9959 2071633 Maybridge1_004390 Cn1cnc([N+](=O)[O-])c1Sc2nnc(c3ccc(cc3)C(C)(C)C)n2c4ccc5OCOc5c4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P15 compound treatment 968000.0 -45300.0 -0.22 1086280.0 96700.0 0.57 996290.0 43852.258064516 0.251163475716155 0.349 0.5247 1511723 Maybridge1_004391 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cc(Cl)c(Cl)cc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P16 compound treatment 1011430.0 -1890.0 -0.01 1005340.0 15700.0 0.09 1082620.0 130182.258064516 0.745617896436645 0.4791 0.6375 2071634 Maybridge1_004392 OC(=O)c1ccccc1SCCS(=O)(=O)c2ccc(Cl)cc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P17 compound treatment 647520.0 -366000.0 -1.79 735040.0 -255000.0 -1.51 697690.0 -254747.741935484 -1.45906576124826 -2.7483 -0.9959 2071635 Maybridge1_004393 CC(C)(C)c1ccc(cc1)C(=O)O/N=C/2\CCCc3[nH]c4ccccc4c23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P18 compound treatment 961120.0 -52200.0 -0.26 932030.0 -57600.0 -0.34 990510.0 38072.258064516 0.218058569521733 -0.2191 -0.457 2071636 Maybridge1_004394 Oc1ccc(cc1)n2nnnc2SCC(=O)Nc3ccc(cc3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P19 compound treatment 802500.0 -211000.0 -1.03 860160.0 -129000.0 -0.77 820220.0 -132217.741935484 -0.757276114881048 -1.4764 -0.9893 1632411 Maybridge1_004395 Cc1ccc(cc1)S(=O)(=O)NC2C(C)(C)C3CC[C@]2(C)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P20 compound treatment 818830.0 -194000.0 -0.95 876900.0 -113000.0 -0.67 769160.0 -183277.741935484 -1.04972187790651 -1.5417 -0.9841 2071637 Maybridge1_004396 Cc1ccc(OCC(O)CN2CCN(CC2)c3nc(ns3)c4ccccc4)c(c1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P21 compound treatment 719210.0 -294000.0 -1.44 806720.0 -183000.0 -1.09 734470.0 -217967.741935484 -1.24840858999725 -2.1784 -0.9936 1113187 Maybridge1_004397 Clc1ccc2noc(c3ccccc3)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P22 compound treatment 933200.0 -80100.0 -0.39 909350.0 -80300.0 -0.48 803200.0 -149237.741935484 -0.854758035889536 -0.9951 -0.9438 2071638 Maybridge1_004398 OC(CSc1ccccc1)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P23 compound treatment 994130.0 -19200.0 -0.09 1040200.0 50600.0 0.3 887560.0 -64877.741935484 -0.371586775238772 -0.095 -0.1951 1555086 Maybridge1_004399 CC(C)(C)OC(=O)N1CCC(CC1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.553 P24 compound treatment 852900.0 -160000.0 -0.78 982610.0 -7020.0 -0.04 832290.0 -120147.741935484 -0.688145281357403 -0.8739 -0.8372 2071639 Maybridge1_004400 COc1ccc(cc1)c2ccnc(SCC(=O)c3ccc(Cl)s3)n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A01 compound treatment 1056930.0 72900.0 0.36 1048490.0 -34100.0 -0.2 877410.0 -355134.19354839 -2.03402840205036 -1.0858 -0.5233 1341040 Maybridge1_004401 CC(C)(C)n1nc(cc1N)C2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A02 compound treatment 957920.0 -26100.0 -0.13 1064900.0 -17700.0 -0.11 979680.0 -252864.19354839 -1.44827775213625 -0.9706 -0.6658 2071640 Maybridge1_004402 COC(=O)c1scc(c1C)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A03 compound treatment 1030260.0 46200.0 0.23 1028730.0 -53900.0 -0.32 979650.0 -252894.19354839 -1.44844957690889 -0.8908 -0.5936 2071641 Maybridge1_004403 Fc1cccc(Cl)c1CN/C(=C(\N=C\c2ccccc2)/C#N)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A04 compound treatment 975910.0 -8110.0 -0.04 949480.0 -133000.0 -0.79 893120.0 -339424.19354839 -1.94404949611362 -1.6023 -0.7632 2071642 Maybridge1_004404 CC(=O)c1nnc2cc(C)nn2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A05 compound treatment 956610.0 -27400.0 -0.13 1021510.0 -61100.0 -0.36 977230.0 -255314.19354839 -1.46231010856815 -1.1313 -0.7479 2071643 Maybridge1_004405 CN1c2ccccc2C(=O)CS1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A06 compound treatment 1023370.0 39300.0 0.19 1126650.0 44000.0 0.26 1009410.0 -223134.19354839 -1.27799940245457 -0.4756 -0.3607 2071644 Maybridge1_004406 Cc1c(csc1S(=O)(=O)N/N=C/c2c(Cl)cccc2Cl)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A07 compound treatment 994080.0 10100.0 0.05 1037440.0 -45200.0 -0.27 1011110.0 -221434.19354839 -1.26826266533856 -0.8589 -0.6621 2071645 Maybridge1_004407 CCO/C=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A08 compound treatment 950560.0 -33500.0 -0.16 1012860.0 -69700.0 -0.41 1035390.0 -197154.19354839 -1.1291991493523 -0.9858 -0.812 2071646 Maybridge1_004408 CCOC(=O)c1cnc2cc(C)nn2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A09 compound treatment 918590.0 -65400.0 -0.32 906800.0 -176000.0 -1.05 845790.0 -386754.19354839 -2.21513171240808 -2.0671 -0.8368 1582142 Maybridge1_004409 CC(C)(C)c1ccc(cc1)c2cc(NS(=O)(=O)c3ccccc3)[nH]n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A10 compound treatment 1004960.0 20900.0 0.1 1063690.0 -18900.0 -0.11 963520.0 -269024.19354839 -1.54083402966253 -0.8955 -0.5784 2071647 Maybridge1_004410 CSCCC(CC(=O)O)NC(=O)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A11 compound treatment 119360.0 -865000.0 -4.22 1014580.0 -68000.0 -0.4 1008960.0 -223584.19354839 -1.2805767740441 -3.412 -0.7697 1125786 Maybridge1_004411 Cc1cc(=O)n2ncc(C#N)c2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A12 compound treatment 975740.0 -8280.0 -0.04 1003680.0 -78900.0 -0.47 1063370.0 -169174.19354839 -0.968943911407681 -0.8538 -0.7924 2071648 Maybridge1_004412 COC(=O)c1sc(SC)c(c1C)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A13 compound treatment 1011450.0 27400.0 0.13 960490.0 -122000.0 -0.73 1007880.0 -224664.19354839 -1.28676246585897 -1.0848 -0.7312 1490917 Maybridge1_004413 O=S(=O)(CCN1CCN(CCS(=O)(=O)c2ccccc2)CC1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A14 compound treatment 992580.0 8560.0 0.04 1071690.0 -10900.0 -0.06 940360.0 -292184.19354839 -1.67348275413706 -0.9795 -0.5847 1944746 Maybridge1_004414 CC(=O)c1cnc2cc(nn2c1C)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A15 compound treatment 986470.0 2450.0 0.01 1031090.0 -51500.0 -0.31 1020280.0 -212264.19354839 -1.21574155983634 -0.8719 -0.6954 1738962 Maybridge1_004415 COCc1cc(O)nc2n(C)nc(C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A16 compound treatment 1000260.0 16200.0 0.08 1041050.0 -41600.0 -0.25 1071930.0 -160614.19354839 -0.919916576282378 -0.628 -0.657 2071649 Maybridge1_004416 CCO/C=C(\C#N)/S(=O)(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A17 compound treatment 1009060.0 25000.0 0.12 1021510.0 -61100.0 -0.36 996830.0 -235714.19354839 -1.35005125711301 -0.9186 -0.6545 2071650 Maybridge1_004417 COC(=O)c1ccccc1S(=O)(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A18 compound treatment 750830.0 -233000.0 -1.14 798250.0 -284000.0 -1.69 837180.0 -395364.19354839 -2.26444542215444 -2.9414 -0.9653 1242984 Maybridge1_004418 COc1ncccc1C(=O)Nc2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A19 compound treatment 1041120.0 57100.0 0.28 955840.0 -127000.0 -0.75 1008390.0 -224154.19354839 -1.28384144472417 -1.0154 -0.6704 2071651 Maybridge1_004419 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2cccnc2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A20 compound treatment 962970.0 -21100.0 -0.1 807230.0 -275000.0 -1.64 976680.0 -255864.19354839 -1.4654602293998 -1.8509 -0.8413 2071652 Maybridge1_004420 Cn1cc(Br)c(n1)c2cccc(N)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A21 compound treatment 925090.0 -58900.0 -0.29 908740.0 -174000.0 -1.03 1008380.0 -224164.19354839 -1.28389871964838 -1.5044 -0.899 2071653 Maybridge1_004421 O=S(CC#N)c1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A22 compound treatment 972220.0 -11800.0 -0.06 918770.0 -164000.0 -0.97 945340.0 -287204.19354839 -1.64495984187958 -1.5455 -0.808 1235734 Maybridge1_004422 Cc1ncc(c(N)n1)S(=O)(=O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A23 mock treatment 1089950.0 106000.0 0.52 955960.0 -127000.0 -0.75 1025370.0 -207174.19354839 -1.18658862341253 -0.8211 -0.5482 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 A24 mock treatment 1023650.0 39600.0 0.19 863840.0 -219000.0 -1.3 902900.0 -329644.19354839 -1.88803462023447 -1.7294 -0.7516 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B01 compound treatment 648160.0 -336000.0 -1.64 671970.0 -411000.0 -2.44 655070.0 -577474.19354839 -3.30747906697557 -4.2668 -0.9639 2071654 Maybridge1_004423 FC(F)(F)c1ccc(N/N=C(\C#N)/C(=O)C2CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B02 compound treatment 974460.0 -9560.0 -0.05 951710.0 -131000.0 -0.78 995090.0 -237454.19354839 -1.36001709392587 -1.2616 -0.8047 1515343 Maybridge1_004424 NC(=O)c1ccc(s1)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B03 compound treatment 981060.0 -2960.0 -0.01 1040080.0 -42500.0 -0.25 982080.0 -250464.19354839 -1.43453177032542 -0.9826 -0.6745 2071655 Maybridge1_004425 Cc1cc(n2nc(cc2n1)c3ccc(cc3)C(C)(C)C)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B04 compound treatment 996770.0 12700.0 0.06 1036860.0 -45700.0 -0.27 1037550.0 -194994.19354839 -1.11682776572255 -0.7659 -0.6653 2071656 Maybridge1_004426 CCSc1sc(C(=O)OC)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B05 compound treatment 959540.0 -24500.0 -0.12 918800.0 -164000.0 -0.97 921220.0 -311324.19354839 -1.78310695907845 -1.6609 -0.816 2071657 Maybridge1_004427 N/C(=N\OC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/CSc2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B06 compound treatment 853080.0 -131000.0 -0.64 845520.0 -237000.0 -1.41 852000.0 -380544.19354839 -2.17956398447255 -2.4417 -0.9133 1465696 Maybridge1_004428 CCOC(=O)c1sc(SC)c2C(=O)CCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B07 compound treatment 968550.0 -15500.0 -0.08 1025790.0 -56800.0 -0.34 1044450.0 -188094.19354839 -1.07730806801641 -0.8607 -0.7606 2071658 Maybridge1_004429 COC(=O)c1sc(SC)c(C#N)c1c2ccc(C)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B08 compound treatment 955200.0 -28800.0 -0.14 883300.0 -199000.0 -1.19 895300.0 -337244.19354839 -1.93156356263544 -1.8808 -0.8283 2071659 Maybridge1_004430 CC(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)CC(C)(C)Cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B09 compound treatment 992410.0 8390.0 0.04 1029530.0 -53100.0 -0.32 947560.0 -284984.19354839 -1.63224480870456 -1.1009 -0.662 2071660 Maybridge1_004431 CC(C)S(=O)(=O)c1cnc(nc1N)c2cccnc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B10 compound treatment 232170.0 -752000.0 -3.67 204370.0 -878000.0 -5.22 176640.0 -1055904.19354839 -6.04768326604083 -8.6277 -0.981 2071661 Maybridge1_004432 CCOC(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)/C(=C/N(C)C)/CCc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B11 compound treatment 994560.0 10500.0 0.05 920050.0 -163000.0 -0.97 1002690.0 -229854.19354839 -1.3164881515249 -1.2884 -0.7885 1242567 Maybridge1_004433 CC(C)(C)S(=O)(=O)c1cnc(nc1N)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B12 compound treatment 769830.0 -214000.0 -1.05 703550.0 -379000.0 -2.25 645220.0 -587324.19354839 -3.3638948673242 -3.8477 -0.92 2071662 Maybridge1_004434 CNC(=O)c1sc(SC)c2C=CCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B13 compound treatment 1159770.0 176000.0 0.86 1088020.0 5410.0 0.03 1033080.0 -199464.19354839 -1.14242965684523 -0.1452 -0.1016 1481192 Maybridge1_004435 CC(C)(C)S(=O)(=O)c1cnc(N)nc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B14 compound treatment 1063200.0 79200.0 0.39 1032000.0 -50600.0 -0.3 1016740.0 -215804.19354839 -1.23601688300732 -0.664 -0.4994 2071663 Maybridge1_004436 Cc1csc2sc(COC(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c(C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B15 compound treatment 1039040.0 55000.0 0.27 994610.0 -88000.0 -0.52 1179940.0 -52604.1935483899 -0.301290119870701 -0.3209 -0.4855 2071664 Maybridge1_004437 CSc1sc(C(=O)O)c(c1C#N)c2cccc(c2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B16 compound treatment 874760.0 -109000.0 -0.53 797610.0 -285000.0 -1.69 874770.0 -357774.19354839 -2.04914898204227 -2.4698 -0.9106 2071665 Maybridge1_004438 Cn1cncc1S(=O)(=O)/C(=N/Nc2ccc(OC(F)(F)F)cc2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B17 compound treatment 1036490.0 52500.0 0.26 860660.0 -222000.0 -1.32 942570.0 -289974.19354839 -1.66082499588625 -1.5729 -0.7361 2071666 Maybridge1_004439 Cn1ncc(C(=O)N=S(=O)(C)c2ccccc2)c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B18 compound treatment 56890.0 -927000.0 -4.53 35790.0 -1050000.0 -6.22 35870.0 -1196674.19354839 -6.85394237417037 -10.1664 -0.9863 1666267 Maybridge1_004440 CCOC(=O)c1sc(c2C(=O)CC(C)(C)Cc12)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B19 compound treatment 1131040.0 147000.0 0.72 905780.0 -177000.0 -1.05 1067720.0 -164824.19354839 -0.944029319375547 -0.7374 -0.4652 1154613 Maybridge1_004441 CCCS(=O)(=O)c1cscc1NC(=O)c2c(C)onc2c3c(F)cccc3Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B20 compound treatment 948480.0 -35500.0 -0.17 1067430.0 -15200.0 -0.09 1069990.0 -162554.19354839 -0.931027911579468 -0.6899 -0.7252 2071667 Maybridge1_004442 COC(=O)c1sccc1N/C=C(\C#N)/C(=O)C2CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B21 compound treatment 1086610.0 103000.0 0.5 1042460.0 -40100.0 -0.24 1008320.0 -224224.19354839 -1.28424236919365 -0.5899 -0.4216 2071668 Maybridge1_004443 O=S(=O)(CC#N)Cc1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B22 compound treatment 1107370.0 123000.0 0.6 959200.0 -123000.0 -0.73 1090620.0 -141924.19354839 -0.81286974293052 -0.5451 -0.436 2071669 Maybridge1_004444 CC(=O)OCc1ccc(/C=C(/C#N)\S(=O)(=O)c2ccccn2)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B23 mock treatment 1016000.0 32000.0 0.16 927730.0 -155000.0 -0.92 1172190.0 -60354.1935483899 -0.345678186134848 -0.6411 -0.6436 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 B24 mock treatment 993950.0 9930.0 0.05 947370.0 -135000.0 -0.8 1021120.0 -211424.19354839 -1.21093046620255 -1.1354 -0.7807 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C01 compound treatment 876530.0 -107000.0 -0.53 858760.0 -224000.0 -1.33 837020.0 -395524.19354839 -2.26536182094183 -2.3796 -0.8881 1573411 Maybridge1_004445 Clc1ccc(cc1)S(=O)(=O)CCNC2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C02 compound treatment 903440.0 -80600.0 -0.39 1055430.0 -27200.0 -0.16 1025560.0 -206984.19354839 -1.18550039985251 -1.0051 -0.7979 2071670 Maybridge1_004446 CSc1sc(C(=O)O)c(c1C#N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C03 compound treatment 864110.0 -120000.0 -0.59 990880.0 -91700.0 -0.55 1067110.0 -165434.19354839 -0.947523089752467 -1.2002 -0.9676 2071671 Maybridge1_004447 Brc1ccc(N/N=C(\C#N)/C(=O)C2CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C04 compound treatment 1020730.0 36700.0 0.18 1075400.0 -7210.0 -0.04 946260.0 -286284.19354839 -1.6396905488521 -0.8679 -0.526 1522059 Maybridge1_004448 Cc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C05 compound treatment 885980.0 -98000.0 -0.48 883090.0 -200000.0 -1.19 903150.0 -329394.19354839 -1.88660274712918 -2.0508 -0.8996 2071672 Maybridge1_004449 Fc1cccc(Cl)c1CN/C(=C(\NCc2ccccc2Cl)/C#N)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C06 compound treatment 937070.0 -47000.0 -0.23 1190310.0 108000.0 0.64 1155460.0 -77084.1935483899 -0.441499134341194 -0.0176 -0.0217 2071673 Maybridge1_004450 Fc1ccc(SCC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C07 compound treatment 941310.0 -42700.0 -0.21 1062780.0 -19800.0 -0.12 1080120.0 -152424.19354839 -0.873008413352912 -0.6926 -0.765 2071674 Maybridge1_004451 Clc1ccc(cc1)S(=O)(=O)/C(=C/N2CCOCC2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C08 compound treatment 981630.0 -2390.0 -0.01 1069190.0 -13400.0 -0.08 1095150.0 -137394.19354839 -0.786924202262573 -0.5071 -0.6411 2071675 Maybridge1_004452 COC(=O)CSCCS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C09 compound treatment 1027570.0 43500.0 0.21 1031400.0 -51200.0 -0.3 1056010.0 -176534.19354839 -1.01109825562757 -0.6367 -0.5911 2071676 Maybridge1_004453 CN1c2ccccc2C(=O)/C(=N\Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)/S1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C10 compound treatment 953500.0 -30500.0 -0.15 1091840.0 9230.0 0.05 1147100.0 -85444.1935483899 -0.48938097098226 -0.3369 -0.6548 1609422 Maybridge1_004454 COc1cscc1C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C11 compound treatment 913190.0 -70800.0 -0.35 966120.0 -116000.0 -0.69 1124740.0 -107804.19354839 -0.61744770151985 -0.9562 -0.9655 2071677 Maybridge1_004455 Nc1ccc(cc1)C2SCCS2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C12 compound treatment 947000.0 -37000.0 -0.18 893940.0 -189000.0 -1.12 951690.0 -280854.19354839 -1.60859026500509 -1.6809 -0.8535 2071678 Maybridge1_004456 COC(=O)c1scc(c1N)S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C13 compound treatment 1018200.0 34200.0 0.17 1253190.0 171000.0 1.01 1200080.0 -32464.1935483899 -0.185938422508132 0.5747 0.5501 1673936 Maybridge1_004457 COCc1cc(=O)n2nc(cc2[nH]1)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C14 compound treatment 1057990.0 74000.0 0.36 1055620.0 -27000.0 -0.16 1067880.0 -164664.19354839 -0.943112920588158 -0.4285 -0.419 2071679 Maybridge1_004458 CC(=O)c1cnc2cc(C)nn2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C15 compound treatment 875970.0 -108000.0 -0.53 880880.0 -202000.0 -1.2 900960.0 -331584.19354839 -1.89914595553156 -2.0938 -0.9074 1413264 Maybridge1_004459 CSc1nc(N)n2nc(cc2n1)C3CC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C16 compound treatment 1102720.0 119000.0 0.58 1044160.0 -38400.0 -0.23 1052370.0 -180174.19354839 -1.03194632804066 -0.393 -0.3259 2071680 Maybridge1_004460 COC(=O)[C@H](CCSC)NC(=O)c1cccnc1SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C17 compound treatment 866400.0 -118000.0 -0.57 780590.0 -302000.0 -1.8 807120.0 -425424.19354839 -2.43661384433512 -2.7755 -0.9008 2071681 Maybridge1_004461 CCOC(=O)/C(=N/Nc1cc(Cl)cc(Cl)c1)/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C18 compound treatment 1060390.0 76400.0 0.37 1078350.0 -4260.0 -0.03 1126770.0 -105774.19354839 -0.605820891904854 -0.149 -0.2092 2071682 Maybridge1_004462 CCCS(=O)(=O)/C(=C/Nc1ncccn1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C19 compound treatment 989610.0 5590.0 0.03 1080160.0 -2450.0 -0.01 1085010.0 -147534.19354839 -0.845000975413341 -0.4805 -0.5683 2071683 Maybridge1_004463 N#CCSc1nc2ccccc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C20 compound treatment 1041730.0 57700.0 0.28 931940.0 -151000.0 -0.9 1082720.0 -149824.19354839 -0.858116933057844 -0.8499 -0.6681 2071684 Maybridge1_004464 CCCS(=O)(=O)c1csc(C(=O)OC)c1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C21 compound treatment 589520.0 -395000.0 -1.93 658130.0 -424000.0 -2.52 691110.0 -541434.19354839 -3.10106024011623 -4.3606 -0.9824 2071685 Maybridge1_004465 Cn1nc(cc1N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C22 compound treatment 1053180.0 69200.0 0.34 938170.0 -144000.0 -0.86 1103110.0 -129434.19354839 -0.741333362589979 -0.7288 -0.6156 2071686 Maybridge1_004466 CS(=O)(=O)c1scc(c1C#N)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C23 mock treatment 1127470.0 143000.0 0.7 1007880.0 -74700.0 -0.44 1211750.0 -20794.1935483899 -0.119098585952958 0.0793 0.0946 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 C24 mock treatment 964890.0 -19100.0 -0.09 938900.0 -144000.0 -0.85 1113850.0 -118694.19354839 -0.679820093986503 -0.9398 -0.8575 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D01 compound treatment 988800.0 4780.0 0.02 1040670.0 -41900.0 -0.25 896360.0 -336184.19354839 -1.92549242066899 -1.2422 -0.6397 2071687 Maybridge1_004467 Clc1ccc(N/C=C(\C#N)/S(=O)(=O)c2ccccn2)nc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D02 compound treatment 893120.0 -90900.0 -0.44 1001440.0 -81200.0 -0.48 968160.0 -264384.19354839 -1.51425846482825 -1.4093 -0.854 2071688 Maybridge1_004468 CC(C)S(=O)(=O)/C(=C/Nc1ccc(Cl)cc1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D03 compound treatment 738480.0 -246000.0 -1.2 785500.0 -297000.0 -1.77 765840.0 -466704.19354839 -2.67304473148144 -3.256 -0.9517 1336734 Maybridge1_004469 CCOC(=O)c1cnc2n(C)nc(C)c2c1Oc3ccc(OC)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D04 compound treatment 807680.0 -176000.0 -0.86 927310.0 -155000.0 -0.92 888360.0 -344184.19354839 -1.97131236003843 -2.1687 -0.9263 2071689 Maybridge1_004470 CCCSc1sc(C(=O)OC)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D05 compound treatment 901820.0 -82200.0 -0.4 852920.0 -230000.0 -1.37 812700.0 -419844.19354839 -2.40465443662493 -2.4088 -0.862 1347108 Maybridge1_004471 COC(=O)C1=C(CSC1)Nc2ccccc2N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D06 compound treatment 881660.0 -102000.0 -0.5 1053500.0 -29100.0 -0.17 1106210.0 -126334.19354839 -0.72357813608432 -0.8064 -0.8996 2071690 Maybridge1_004472 CCOC(=O)CSc1sc(C(=O)OCC)c2CCCC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D07 compound treatment 964920.0 -19100.0 -0.09 927730.0 -155000.0 -0.92 987290.0 -245254.19354839 -1.40469153481107 -1.3966 -0.8302 2071691 Maybridge1_004473 CC1(C)OC(=O)C(=CNc2ccccn2)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D08 compound treatment 977150.0 -6870.0 -0.03 933830.0 -149000.0 -0.88 1056640.0 -175904.19354839 -1.00748993540222 -1.1118 -0.829 2071692 Maybridge1_004474 CCO/C=C(\C#N)/S(=O)(=O)Cc1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D09 compound treatment 938760.0 -45300.0 -0.22 871630.0 -211000.0 -1.25 930370.0 -302174.19354839 -1.73070040342465 -1.8512 -0.8614 2071693 Maybridge1_004475 COC(=O)c1sc(SC)c(c1N)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D10 compound treatment 984280.0 258.0 0.0 812240.0 -270000.0 -1.61 905400.0 -327144.19354839 -1.87371588918152 -2.0093 -0.8138 2071694 Maybridge1_004476 CSc1sc(C#N)c2CCCC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D11 compound treatment 1077610.0 93600.0 0.46 925680.0 -157000.0 -0.93 985720.0 -246824.19354839 -1.41368369791233 -1.091 -0.6218 1239901 Maybridge1_004477 CC(C)(C)S(=O)(=O)c1cnc(nc1N)N2CCOCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D12 compound treatment 1126650.0 143000.0 0.7 981690.0 -101000.0 -0.6 1305760.0 73215.8064516101 0.419342976562195 0.298 0.2948 2071695 Maybridge1_004478 CCOC(=O)c1sc2sc(C#N)c(C)c2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D13 compound treatment 1102080.0 118000.0 0.58 1191840.0 109000.0 0.65 991250.0 -241294.19354839 -1.3820106648232 -0.0899 -0.055 2071696 Maybridge1_004479 Fc1ccc(NC(=O)CSc2cccs2)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D14 compound treatment 990190.0 6170.0 0.03 803650.0 -279000.0 -1.66 930310.0 -302234.19354839 -1.73104405296992 -1.9397 -0.809 2071697 Maybridge1_004480 CCOC(=O)c1sc(SC)c(C(=O)C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D15 compound treatment 1013770.0 29700.0 0.15 858440.0 -224000.0 -1.33 976030.0 -256514.19354839 -1.46918309947356 -1.5339 -0.7712 2071698 Maybridge1_004481 Cc1cscc1S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D16 compound treatment 989400.0 5380.0 0.03 861350.0 -221000.0 -1.32 967150.0 -265394.19354839 -1.52004323217364 -1.6221 -0.8068 2071699 Maybridge1_004482 CCOC(=O)c1sc(SC)c2C(=O)CC(Cc12)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D17 compound treatment 998400.0 14400.0 0.07 876920.0 -206000.0 -1.22 1140710.0 -91834.1935483899 -0.525979647553602 -0.9693 -0.727 2071700 Maybridge1_004483 COC(=O)C(CCSC)NC(=O)c1ccc(cc1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D18 compound treatment 886630.0 -97400.0 -0.48 906190.0 -176000.0 -1.05 1028970.0 -203574.19354839 -1.16596965069628 -1.5536 -0.9479 1555939 Maybridge1_004484 NNC(=O)CC1Sc2ccccc2NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D19 compound treatment 1006530.0 22500.0 0.11 983740.0 -98900.0 -0.59 1153490.0 -79054.1935483899 -0.452782294410919 -0.5374 -0.7163 1460263 Maybridge1_004485 CC(C)Sc1c(cnc2n(C)nc(C)c12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D20 compound treatment 905610.0 -78400.0 -0.38 873070.0 -210000.0 -1.25 1111080.0 -121464.19354839 -0.695685247993172 -1.3422 -0.9084 2071701 Maybridge1_004486 COC(=O)c1sccc1N/N=C(\C#N)/S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D21 compound treatment 1077850.0 93800.0 0.46 925470.0 -157000.0 -0.93 1006020.0 -226524.19354839 -1.29741560176237 -1.0239 -0.6156 2071702 Maybridge1_004487 NNC(=O)CSCCS(=O)(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D22 compound treatment 736640.0 -247000.0 -1.21 653290.0 -429000.0 -2.55 772340.0 -460204.19354839 -2.63581603074376 -3.6936 -0.956 1417176 Maybridge1_004488 CCCSc1sc(C(=O)OCC)c2CCCC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D23 mock treatment 973140.0 -10900.0 -0.05 969630.0 -113000.0 -0.67 1165140.0 -67404.1935483899 -0.386057007704169 -0.6415 -0.8259 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 D24 mock treatment 1002680.0 18700.0 0.09 995650.0 -87000.0 -0.52 1183550.0 -48994.1935483899 -0.280613872230241 -0.4079 -0.6852 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E01 compound treatment 823630.0 -160000.0 -0.78 839460.0 -243000.0 -1.45 982020.0 -250524.19354839 -1.43487541987069 -2.1156 -0.9693 2071703 Maybridge1_004489 Clc1cccc(/C=C(\C#N)/C(=O)C2CC2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E02 compound treatment 818590.0 -165000.0 -0.81 931840.0 -151000.0 -0.9 1020050.0 -212494.19354839 -1.21705888309321 -1.6869 -0.9841 1003712 Maybridge1_004490 N#CCSc1ccc2ccccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E03 compound treatment 817510.0 -167000.0 -0.81 972190.0 -110000.0 -0.66 949760.0 -282784.19354839 -1.61964432537797 -1.7839 -0.9254 2071704 Maybridge1_004491 Clc1ccc(N/N=C(\C#N)/C(=O)C2CC2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E04 compound treatment 923590.0 -60400.0 -0.3 1000760.0 -81800.0 -0.49 1273350.0 40805.8064516101 0.233714947191744 -0.3165 -0.5144 2071705 Maybridge1_004492 CN1c2ccccc2C(=O)/C(=C\Nc3ccc(F)cc3)/S1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E05 compound treatment 879040.0 -105000.0 -0.51 1198320.0 116000.0 0.69 1030570.0 -201974.19354839 -1.15680566282239 -0.5667 -0.3935 2071706 Maybridge1_004493 O=C(NC(=S)Nc1cc(n[nH]1)c2cccs2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E06 compound treatment 1013620.0 29600.0 0.14 1252030.0 169000.0 1.01 1073190.0 -159354.19354839 -0.912699935831691 0.1382 0.1011 2071707 Maybridge1_004494 Fc1ccc(cc1)S(=O)(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E07 compound treatment 989440.0 5420.0 0.03 1010770.0 -71800.0 -0.43 1101280.0 -131264.19354839 -0.751814673720739 -0.6654 -0.7692 2071708 Maybridge1_004495 CN(C)/C=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E08 compound treatment 927050.0 -57000.0 -0.28 1083840.0 1230.0 0.01 1106630.0 -125914.19354839 -0.721172589267424 -0.5728 -0.741 2071709 Maybridge1_004496 OC(=O)CSCCS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E09 compound treatment 1164920.0 181000.0 0.88 1078720.0 -3890.0 -0.02 1179940.0 -52604.1935483899 -0.301290119870701 0.323 0.3458 2071710 Maybridge1_004497 NC(=S)Nc1ccccc1C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E10 compound treatment 973020.0 -11000.0 -0.05 884520.0 -198000.0 -1.18 1109320.0 -123224.19354839 -0.70576563465445 -1.1186 -0.814 1632861 Maybridge1_004498 Clc1ccc(OCc2cccc(C#N)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E11 compound treatment 457200.0 -527000.0 -2.57 514000.0 -569000.0 -3.38 550400.0 -682144.19354839 -3.90697569870051 -5.6939 -0.9864 2071711 Maybridge1_004499 Clc1ccc(cc1)S(=O)(=O)/C(=N/Nc2ccccc2Cl)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E12 compound treatment 1058810.0 74800.0 0.37 1072340.0 -10300.0 -0.06 1192480.0 -40064.1935483899 -0.229467364909101 0.0432 0.0992 1931850 Maybridge1_004500 OC(=O)CSCCS(=O)(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E13 compound treatment 1069860.0 85800.0 0.42 1260330.0 178000.0 1.06 1193250.0 -39294.1935483899 -0.225057195744793 0.7224 0.6232 1613806 Maybridge1_004501 COCc1cc(=O)n2nc(C)cc2[nH]1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E14 compound treatment 1132690.0 149000.0 0.73 1087250.0 4640.0 0.03 1176100.0 -56444.1935483899 -0.323283690768034 0.2487 0.3126 2071712 Maybridge1_004502 Cc1cccc(c1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E15 compound treatment 770920.0 -213000.0 -1.04 866120.0 -216000.0 -1.29 1011220.0 -221324.19354839 -1.26763264117223 -2.0762 -0.9957 2071713 Maybridge1_004503 CSc1c(C#N)c(nn1C)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E16 compound treatment 931000.0 -53000.0 -0.26 1046260.0 -36300.0 -0.22 1122660.0 -109884.19354839 -0.629360885755905 -0.6377 -0.893 2071714 Maybridge1_004504 CC(C)(C)S(=O)(=O)/C(=C/N1CCOCC1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E17 compound treatment 815530.0 -168000.0 -0.82 998370.0 -84200.0 -0.5 1008500.0 -224044.19354839 -1.28321142055784 -1.5054 -0.9381 2071715 Maybridge1_004505 CSc1nc(nc(c1C#N)c2ccccc2)c3cccnc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E18 compound treatment 846140.0 -138000.0 -0.67 974600.0 -108000.0 -0.64 998090.0 -234454.19354839 -1.34283461666233 -1.535 -0.9395 2071716 Maybridge1_004506 FC(F)(F)c1cc(CN/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E19 compound treatment 1028770.0 44700.0 0.22 1144860.0 62300.0 0.37 1032480.0 -200064.19354839 -1.14586615229794 -0.3216 -0.2628 2071717 Maybridge1_004507 Cc1n[nH]c(N)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E20 compound treatment 979860.0 -4160.0 -0.02 962890.0 -120000.0 -0.71 1067640.0 -164904.19354839 -0.944487518769242 -0.9681 -0.8184 2071718 Maybridge1_004508 COC(=O)c1scc(C#N)c1n2cccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E21 compound treatment 1000160.0 16100.0 0.08 1004080.0 -78500.0 -0.47 1126410.0 -106134.19354839 -0.607882789176479 -0.575 -0.7462 2071719 Maybridge1_004509 Clc1ccc(cc1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E22 compound treatment 1050420.0 66400.0 0.32 1019380.0 -63200.0 -0.38 1146450.0 -86094.1935483899 -0.493103841056027 -0.3145 -0.4494 2071720 Maybridge1_004510 CS(=O)(=O)c1csc(C(=O)O)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E23 mock treatment 908710.0 -75300.0 -0.37 1114360.0 31800.0 0.19 1253370.0 20825.8064516101 0.119279648616563 -0.0346 -0.0803 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 E24 mock treatment 1070840.0 86800.0 0.42 1213780.0 131000.0 0.78 1331920.0 99375.8064516101 0.56917417830027 1.0239 0.9708 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F01 compound treatment 886680.0 -97300.0 -0.48 1075530.0 -7080.0 -0.04 1015250.0 -217294.19354839 -1.24455084671487 -1.0174 -0.7633 2071721 Maybridge1_004511 Clc1ccc(Sc2ccccc2/C=C(\C#N)/S(=O)(=O)c3ccc(Cl)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F02 compound treatment 863610.0 -120000.0 -0.59 1004500.0 -78100.0 -0.46 904270.0 -328274.19354839 -1.88018795561746 -1.6933 -0.8366 2071722 Maybridge1_004512 CC(=O)c1cc(ccc1Sc2ccc(Cl)cc2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F03 compound treatment 778950.0 -205000.0 -1.0 878900.0 -204000.0 -1.21 818300.0 -414244.19354839 -2.37258047906632 -2.6477 -0.9303 1672437 Maybridge1_004513 CCOC(=O)c1cnc2n(C)nc(C)c2c1Oc3ccc(F)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F04 compound treatment 883640.0 -100000.0 -0.49 1009410.0 -73200.0 -0.44 1017530.0 -215014.19354839 -1.23149216399458 -1.2455 -0.8927 1590459 Maybridge1_004514 NC(=S)c1ccc(cc1)C2OCCO2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F05 compound treatment 880800.0 -103000.0 -0.5 912770.0 -170000.0 -1.01 968230.0 -264314.19354839 -1.51385754035877 -1.7483 -0.9258 2071723 Maybridge1_004515 CCSc1sc(C(=O)OC)c(c1C#N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F06 compound treatment 891310.0 -92700.0 -0.45 1002510.0 -80100.0 -0.48 1057090.0 -175454.19354839 -1.00491256381269 -1.1167 -0.93 1200963 Maybridge1_004516 CCOC(=O)c1sc(SC(C)C)c2c1-c3ccccc3N(C)S2(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F07 compound treatment 1123120.0 139000.0 0.68 1224170.0 142000.0 0.84 991870.0 -240674.19354839 -1.37845961952207 0.0825 0.0471 2071724 Maybridge1_004517 Cc1cc(C)nc(NC=C2C(=O)OC(C)(C)OC2=O)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F08 compound treatment 910930.0 -73100.0 -0.36 922270.0 -160000.0 -0.95 1054340.0 -178204.19354839 -1.02066316797094 -1.3459 -0.9336 2071725 Maybridge1_004518 COC(=O)c1scc(c1N)S(=O)(=O)Cc2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F09 compound treatment 983240.0 -782.0 0.0 1077940.0 -4670.0 -0.03 1019040.0 -213504.19354839 -1.2228436504386 -0.7242 -0.5921 2071726 Maybridge1_004519 COC(=O)c1sc(SC)c(C#N)c1c2ccc(OC)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F10 compound treatment 967930.0 -16100.0 -0.08 1021990.0 -60600.0 -0.36 1091440.0 -141104.19354839 -0.808173199145152 -0.7201 -0.8106 2071727 Maybridge1_004520 CSc1sc(C#N)c2CCCC(O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F11 compound treatment 952050.0 -32000.0 -0.16 977390.0 -105000.0 -0.63 1234670.0 2125.80645161006 0.0121755403404926 -0.4444 -0.689 2071728 Maybridge1_004521 COC(=O)c1sc(SC)c(c1SC)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F12 compound treatment 912330.0 -71700.0 -0.35 955530.0 -127000.0 -0.76 1301980.0 69435.8064516101 0.397693055210134 -0.4089 -0.443 1293398 Maybridge1_004522 CCOC(=O)c1sc(c2C(O)CCCc12)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F13 compound treatment 1097780.0 114000.0 0.56 996250.0 -86400.0 -0.51 1198400.0 -34144.1935483899 -0.195560609775714 -0.0885 -0.1132 1592097 Maybridge1_004523 CC(C)(C)S(=O)(=O)c1cnc(nc1N)c2ccncc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F14 compound treatment 1062090.0 78100.0 0.38 1340420.0 258000.0 1.53 1225690.0 -6854.19354838994 -0.0392573416017058 1.0827 0.6851 1445978 Maybridge1_004524 CCOC(=O)c1sc2sc(C(=O)c3ccc(Cl)cc3)c(C)c2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F15 compound treatment 767460.0 -217000.0 -1.06 828390.0 -254000.0 -1.51 954050.0 -278494.19354839 -1.5950733828911 -2.4046 -0.9859 1390085 Maybridge1_004525 OC(=O)c1sc(SC2CCCCC2)c(C#N)c1c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F16 compound treatment 994360.0 10300.0 0.05 1011310.0 -71300.0 -0.42 1078080.0 -154464.19354839 -0.88469249789212 -0.7264 -0.7395 2071729 Maybridge1_004526 CSc1sc(C#N)c(C)c1C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F17 compound treatment 1129160.0 145000.0 0.71 1068570.0 -14000.0 -0.08 1190880.0 -41664.1935483899 -0.23863135278299 0.2234 0.2968 2071730 Maybridge1_004527 CC(C)S(=O)(=O)c1csc(C(=O)N)c1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F18 compound treatment 616370.0 -368000.0 -1.8 785470.0 -297000.0 -1.77 778990.0 -453554.19354839 -2.59772820614292 -3.557 -0.9829 2071731 Maybridge1_004528 CSc1sc(Br)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F19 compound treatment 994990.0 11000.0 0.05 1026240.0 -56400.0 -0.34 1073660.0 -158884.19354839 -0.910008014393737 -0.688 -0.7083 2071732 Maybridge1_004529 FC(F)(F)c1cc(n2ncc(C#N)c2n1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F20 compound treatment 1016600.0 32600.0 0.16 1048210.0 -34400.0 -0.2 1175680.0 -56864.1935483899 -0.325689237584929 -0.2142 -0.5147 2071733 Maybridge1_004530 COC(=O)c1sccc1N/N=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F21 compound treatment 1045120.0 61100.0 0.3 1055520.0 -27100.0 -0.16 1246890.0 14345.8064516101 0.0821654977273151 0.1268 0.3633 1083260 Maybridge1_004531 Cc1ccc(cc1)S(=O)(=O)N=S(=O)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F22 compound treatment 906400.0 -77600.0 -0.38 1066680.0 -15900.0 -0.09 1028910.0 -203634.19354839 -1.16631330024155 -0.947 -0.7699 1056221 Maybridge1_004532 CC(=C(C#N)C#N)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F23 mock treatment 916320.0 -67700.0 -0.33 1102080.0 19500.0 0.12 1372250.0 139705.80645161 0.800163947646469 0.3379 0.3868 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 F24 mock treatment 908810.0 -75200.0 -0.37 1125010.0 42400.0 0.25 1253230.0 20685.8064516101 0.118477799677598 0.0018 0.004 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G01 compound treatment 1015860.0 31800.0 0.16 1185490.0 103000.0 0.61 1131950.0 -100594.19354839 -0.576152481163141 0.1104 0.1292 2071734 Maybridge1_004533 CN(C)c1ccc(/C=C(\C#N)/C(=O)C2CC2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G02 compound treatment 958560.0 -25500.0 -0.12 1138560.0 56000.0 0.33 1101380.0 -131164.19354839 -0.75124192447862 -0.3135 -0.3772 2071735 Maybridge1_004534 O=S(=O)(CC#N)c1ccc2ccccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G03 compound treatment 901350.0 -82700.0 -0.4 1190140.0 108000.0 0.64 1138280.0 -94264.1935483899 -0.53989745413707 -0.1757 -0.1891 2071736 Maybridge1_004535 CC(C)(C)c1ccc(cc1)c2cc3nc(cc(n3n2)C(F)(F)F)c4cccs4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G04 compound treatment 889850.0 -94200.0 -0.46 1154240.0 71600.0 0.43 1214890.0 -17654.1935483899 -0.101114259750452 -0.0781 -0.1229 2071737 Maybridge1_004536 Cc1c(csc1C(=O)O)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G05 compound treatment 533850.0 -450000.0 -2.2 688530.0 -394000.0 -2.34 718170.0 -514374.19354839 -2.9460742951991 -4.3237 -0.9917 2071738 Maybridge1_004537 Brc1ccc(N=Nc2c(NC(=S)NC(=O)c3ccccc3)[nH]nc2C4CC4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G06 compound treatment 898530.0 -85500.0 -0.42 1108480.0 25900.0 0.15 1205530.0 -27014.1935483899 -0.154723588812699 -0.2417 -0.5128 2071739 Maybridge1_004538 Clc1ccc(cc1Cl)S(=O)(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G07 compound treatment 628120.0 -356000.0 -1.74 718050.0 -365000.0 -2.17 763360.0 -469184.19354839 -2.68724891268596 -3.807 -0.9848 2071740 Maybridge1_004539 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc(c1)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G08 compound treatment 892910.0 -91100.0 -0.45 998080.0 -84500.0 -0.5 1060270.0 -172274.19354839 -0.98669913791334 -1.1169 -0.9358 2071741 Maybridge1_004540 CC1(C)CC(=O)C(=CNc2ccc(F)cc2F)C(=O)C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G09 compound treatment 995040.0 11000.0 0.05 1183650.0 101000.0 0.6 1243800.0 11255.8064516101 0.0644675461458682 0.4152 0.6844 2071742 Maybridge1_004541 Clc1ccc(SCc2cccc(C#N)c2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G10 compound treatment 877350.0 -107000.0 -0.52 953220.0 -129000.0 -0.77 1149920.0 -82624.1935483899 -0.473229442354532 -1.0183 -0.9765 2071743 Maybridge1_004542 CCSc1sc(C(=O)OC)c(c1C#N)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G11 compound treatment 485410.0 -499000.0 -2.44 550240.0 -532000.0 -3.17 476170.0 -756374.19354839 -4.33212746112471 -5.7354 -0.9733 2071744 Maybridge1_004543 Fc1ccc(N/N=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G12 compound treatment 1023880.0 39900.0 0.19 1189000.0 106000.0 0.63 1158930.0 -73614.1935483899 -0.421624735639698 0.2343 0.2985 2071745 Maybridge1_004544 Cc1ccc(cc1)S(=O)(=O)/C(=N/O)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G13 compound treatment 418030.0 -566000.0 -2.77 529930.0 -553000.0 -3.29 595780.0 -636764.19354839 -3.64706209262735 -5.5997 -0.9938 2071746 Maybridge1_004545 Cc1cc(C)n2ncc(/C(=N/OC(=O)c3ccccc3Cl)/N)c2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G14 compound treatment 1081280.0 97300.0 0.48 1236730.0 154000.0 0.92 1213760.0 -18784.1935483899 -0.107586326186386 0.7414 0.7143 2071747 Maybridge1_004546 Clc1ccc(cc1)S(=O)(=O)CCSCCOC(=O)c2ccccc2Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G15 compound treatment 795760.0 -188000.0 -0.92 1078210.0 -4400.0 -0.03 1018670.0 -213874.19354839 -1.22496282263444 -1.2534 -0.8181 2071748 Maybridge1_004547 Clc1ccc(cc1)S(=O)(=O)C(=C2SCCS2)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G16 compound treatment 957830.0 -26200.0 -0.13 1136400.0 53800.0 0.32 1140280.0 -92264.1935483899 -0.52844246929471 -0.1943 -0.308 2071749 Maybridge1_004548 CSc1ncccc1C(=O)NC(CC(C)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G17 compound treatment 1027570.0 43500.0 0.21 1110480.0 27900.0 0.17 1294790.0 62245.8064516101 0.356512384701848 0.4244 0.9493 2071750 Maybridge1_004549 CCOC(=O)Cn1nc(C)c(Br)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G18 compound treatment 1101450.0 117000.0 0.57 1274080.0 191000.0 1.14 1180480.0 -52064.1935483899 -0.298197273963264 0.8165 0.6235 2071751 Maybridge1_004550 COC(=O)c1scc(c1N)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G19 compound treatment 1124760.0 141000.0 0.69 1389020.0 306000.0 1.82 1403680.0 171135.80645161 0.980179034444164 2.0149 0.9241 2071752 Maybridge1_004551 CC1CN(CC(C)O1)/C=C(\C#N)/S(=O)(=O)Cc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G20 compound treatment 906770.0 -77300.0 -0.38 1116050.0 33400.0 0.2 1129970.0 -102574.19354839 -0.587492916157078 -0.4423 -0.6092 2071753 Maybridge1_004552 Nc1ccccc1SCCS(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G21 compound treatment 989890.0 5870.0 0.03 1092920.0 10300.0 0.06 1163410.0 -69134.1935483899 -0.395965569592811 -0.1766 -0.4397 2071754 Maybridge1_004553 CSc1nc(nc(c1C#N)c2ccccc2)N3CCOCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G22 compound treatment 1030130.0 46100.0 0.23 997600.0 -85000.0 -0.51 1138130.0 -94414.1935483899 -0.540756578000247 -0.474 -0.6126 2071755 Maybridge1_004554 COC(=O)c1scc(c1I)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G23 mock treatment 961170.0 -22900.0 -0.11 1134880.0 52300.0 0.31 1167040.0 -65504.1935483899 -0.375174772103926 -0.1016 -0.2033 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 G24 mock treatment 998670.0 14600.0 0.07 1172680.0 90100.0 0.54 1281280.0 48735.8064516101 0.279133962091703 0.5117 0.8413 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H01 compound treatment 954600.0 -29400.0 -0.14 1105700.0 23100.0 0.14 945410.0 -287134.19354839 -1.6445589174101 -0.9532 -0.5754 2071756 Maybridge1_004555 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2ccc(Cl)cn2)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H02 compound treatment 55400.0 -929000.0 -4.54 48520.0 -1030000.0 -6.15 44000.0 -1188544.19354839 -6.80737786078617 -10.1 -0.9869 2071757 Maybridge1_004556 CC(=O)c1cc([N+](=O)[O-])c(Sc2ccc(Cl)cc2)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H03 compound treatment 815600.0 -168000.0 -0.82 862620.0 -220000.0 -1.31 933620.0 -298924.19354839 -1.71208605305582 -2.2188 -0.962 1147627 Maybridge1_004557 CCOC(=O)c1cnc2n(C)nc(C)c2c1Oc3cc(Cl)cc(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H04 compound treatment 625880.0 -358000.0 -1.75 727480.0 -355000.0 -2.11 752810.0 -479734.19354839 -2.74767395772941 -3.8159 -0.9829 1550952 Maybridge1_004558 CCOC(=O)c1sc(SC(C)C)c2C(=O)CC(C)(C)Cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H05 compound treatment 808980.0 -175000.0 -0.86 999080.0 -83500.0 -0.5 933120.0 -299424.19354839 -1.71494979926641 -1.7707 -0.8944 2071758 Maybridge1_004559 COC(=O)c1cc(Cl)cc(Cl)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H06 compound treatment 839150.0 -145000.0 -0.71 974020.0 -109000.0 -0.65 1089470.0 -143074.19354839 -0.819456359214877 -1.2546 -0.9951 2071759 Maybridge1_004560 CSc1sc(C(=O)C)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H07 compound treatment 856530.0 -127000.0 -0.62 1292410.0 210000.0 1.25 1024120.0 -208424.19354839 -1.19374798893901 -0.3285 -0.179 2071760 Maybridge1_004561 CSc1sc(C(=O)O)c(c1C#N)c2cccc(Cl)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H08 compound treatment 922630.0 -61400.0 -0.3 1038240.0 -44400.0 -0.26 884570.0 -347974.19354839 -1.99301955631471 -1.4762 -0.7262 2071761 Maybridge1_004562 CCOC(=O)c1sc(SCc2ccc(Cl)cc2)c(c1N)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H09 compound treatment 929610.0 -54400.0 -0.27 957550.0 -125000.0 -0.74 1140740.0 -91804.1935483899 -0.525807822780967 -0.8864 -0.9343 2071762 Maybridge1_004563 CSc1sc(C(=O)O)c(N)c1S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H10 compound treatment 972710.0 -11300.0 -0.06 1019450.0 -63200.0 -0.38 1039630.0 -192914.19354839 -1.1049145814865 -0.8867 -0.7589 1553259 Maybridge1_004564 CSc1sc(C(=O)NN)c2CCCC(O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H11 compound treatment 1049230.0 65200.0 0.32 1208380.0 126000.0 0.75 970450.0 -262094.19354839 -1.50114250718375 -0.2509 -0.147 2071763 Maybridge1_004565 COC(=O)c1sc(SC)c(c1I)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H12 compound treatment 1098730.0 115000.0 0.56 1369520.0 287000.0 1.71 1022150.0 -210394.19354839 -1.20503114900873 0.6129 0.2834 2071764 Maybridge1_004566 CC(=O)c1sc2sc(C#N)c(C)c2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H13 compound treatment 801120.0 -183000.0 -0.89 894640.0 -188000.0 -1.12 1157290.0 -75254.1935483899 -0.431017823210434 -1.4101 -0.9435 1735674 Maybridge1_004567 CC(C)(C)S(=O)(=O)c1cnc(nc1N)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H14 compound treatment 1089220.0 105000.0 0.51 1274050.0 191000.0 1.14 1004340.0 -228204.19354839 -1.30703778902995 0.1994 0.1103 2071765 Maybridge1_004568 CCOC(=O)c1sc2sc(C(=O)C)c(C)c2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H15 compound treatment 1087250.0 103000.0 0.5 1108410.0 25800.0 0.15 1208500.0 -24044.1935483899 -0.137712936321794 0.3003 0.5511 2071766 Maybridge1_004569 CS(=O)(=NC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H16 compound treatment 1144070.0 160000.0 0.78 1081870.0 -736.0 0.0 1356290.0 123745.80645161 0.708753168604432 0.8581 0.8131 2071767 Maybridge1_004570 CSc1sc(C(=O)O)c(C)c1C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H17 compound treatment 985180.0 1160.0 0.01 1032800.0 -49800.0 -0.3 1050240.0 -182304.19354839 -1.04414588689778 -0.7706 -0.71 2071768 Maybridge1_004571 CNC(=S)NNC(=O)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H18 compound treatment 1224550.0 241000.0 1.18 1091380.0 8770.0 0.05 1353470.0 120925.80645161 0.692601639976704 1.1085 0.812 2071769 Maybridge1_004572 COc1ccc(cc1)C2CC(=O)c3c(SCc4ccccc4)sc(C#N)c3C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H19 compound treatment 1109240.0 125000.0 0.61 984920.0 -97700.0 -0.58 1154490.0 -78054.1935483899 -0.447054801989738 -0.2403 -0.2517 2071770 Maybridge1_004573 Cc1ccc(cc1)S(=O)(=O)/N=S\2/CCCSC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H20 compound treatment 970560.0 -13500.0 -0.07 1023250.0 -59400.0 -0.35 1112770.0 -119774.19354839 -0.686005785801378 -0.6378 -0.8238 2071771 Maybridge1_004574 COC(=O)c1sccc1N/N=C(\C#N)/S(=O)(=O)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H21 compound treatment 1067680.0 83700.0 0.41 1077380.0 -5230.0 -0.03 1125690.0 -106854.19354839 -0.612006583719729 -0.1353 -0.1837 2071772 Maybridge1_004575 O=C(CSCCS(=O)(=O)c1ccccc1)N/N=C/c2ccsc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H22 compound treatment 965190.0 -18800.0 -0.09 1017570.0 -65000.0 -0.39 1308380.0 75835.8064516101 0.434349006705688 -0.0256 -0.0435 2071773 Maybridge1_004576 O=S(=O)(CC#N)Cc1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H23 mock treatment 959090.0 -24900.0 -0.12 1101160.0 18600.0 0.11 1330280.0 97735.8064516101 0.559781090729535 0.3166 0.5426 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 H24 mock treatment 1062160.0 78100.0 0.38 1188750.0 106000.0 0.63 1308550.0 76005.8064516101 0.435322680417288 0.8362 0.9762 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I01 compound treatment 1151930.0 168000.0 0.82 1147410.0 64800.0 0.39 1130620.0 -101924.19354839 -0.583770046083311 0.3591 0.3331 1154606 Maybridge1_004577 Cc1nc2ccc(Br)cc2c(C(=O)O)c1I 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I02 compound treatment 846400.0 -138000.0 -0.67 1053920.0 -28700.0 -0.17 1226720.0 -5824.19354838994 -0.0333580244078902 -0.506 -0.7285 2071774 Maybridge1_004578 N/C(=N\OC(=O)c1ccc(Cl)cc1)/CS(=O)(=O)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I03 compound treatment 825130.0 -159000.0 -0.78 887250.0 -195000.0 -1.16 808680.0 -423864.19354839 -2.42767895615807 -2.5205 -0.8999 2071775 Maybridge1_004579 Nc1[nH]nc(c1Br)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I04 compound treatment 1012590.0 28600.0 0.14 1084890.0 2280.0 0.01 1240240.0 7695.80645161006 0.0440776731264665 0.1139 0.7747 2071776 Maybridge1_004580 CN1c2ccccc2C(=O)/C(=C\Nc3ccccn3)/S1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I05 compound treatment 99700.0 -884000.0 -4.32 107520.0 -975000.0 -5.8 70430.0 -1162114.19354839 -6.65600023609438 -9.6851 -0.9854 2071777 Maybridge1_004581 Clc1ccc(N=Nc2c(NC(=S)NC(=O)c3ccccc3)[nH]nc2C4CC4)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I06 compound treatment 1060970.0 76900.0 0.38 1213280.0 131000.0 0.78 1027420.0 -205124.19354839 -1.17484726394911 -0.0126 -0.0086 1023040 Maybridge1_004582 COc1ccc(cc1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I07 compound treatment 956480.0 -27500.0 -0.13 1303370.0 221000.0 1.31 1318720.0 86175.8064516101 0.493571278340691 0.9652 0.6851 1033270 Maybridge1_004583 O=S(=O)(CC#N)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I08 compound treatment 858420.0 -126000.0 -0.61 910240.0 -172000.0 -1.02 972710.0 -259834.19354839 -1.48819837431188 -1.8053 -0.946 2071778 Maybridge1_004584 Fc1ccc(NC(=O)CSCCS(=O)(=O)c2ccc(Cl)cc2)cc1Cl 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I09 compound treatment 687620.0 -296000.0 -1.45 934180.0 -148000.0 -0.88 716190.0 -516354.19354839 -2.95741473019303 -3.0531 -0.8956 2071779 Maybridge1_004585 CCOC(=O)c1[nH]c(C)c(C(=O)C)c1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I10 compound treatment 485330.0 -499000.0 -2.44 525920.0 -557000.0 -3.31 503050.0 -729494.19354839 -4.17817246484339 -5.7302 -0.9777 2071780 Maybridge1_004586 N/C(=N\O)/c1cccc(COc2ccc(Cl)cc2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I11 compound treatment 967370.0 -16700.0 -0.08 945940.0 -137000.0 -0.81 1032910.0 -199634.19354839 -1.14340333055683 -1.1763 -0.8372 1706372 Maybridge1_004587 Fc1ccccc1C(=O)Nc2ccc(cc2)C3SCCS3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I12 compound treatment 1000350.0 16300.0 0.08 1277180.0 195000.0 1.16 1217500.0 -15044.1935483899 -0.0861655045311719 0.6643 0.5712 2071781 Maybridge1_004588 Nc1c(csc1C(=O)O)S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I13 compound treatment 1071320.0 87300.0 0.43 1522020.0 439000.0 2.61 1131810.0 -100734.19354839 -0.576954330102106 1.4218 0.5247 2071782 Maybridge1_004589 CC(C)(C)N/C=C(\C#N)/S(=O)(=O)c1ccc(Br)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I14 compound treatment 1020640.0 36600.0 0.18 1057490.0 -25100.0 -0.15 1149450.0 -83094.1935483899 -0.475921363792487 -0.2577 -0.4863 2071783 Maybridge1_004590 CCSc1ncccc1C(=O)N[C@@H](CCSC)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I15 compound treatment 902890.0 -81100.0 -0.4 996180.0 -86400.0 -0.51 986270.0 -246274.19354839 -1.41053357708068 -1.34 -0.863 2071784 Maybridge1_004591 COC(=O)c1sc(SC)c(C#N)c1c2cccc(OC)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I16 compound treatment 1088730.0 105000.0 0.51 1143470.0 60900.0 0.36 1056900.0 -175644.19354839 -1.00600078737272 -0.0765 -0.0645 2071785 Maybridge1_004592 CSCCC(NC(=O)c1cccnc1SC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I17 compound treatment 975840.0 -8180.0 -0.04 1100880.0 18300.0 0.11 1196520.0 -36024.1935483899 -0.206328295527533 -0.0795 -0.3359 2071786 Maybridge1_004593 Cc1nn(CC(=O)NN)c(C)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I18 compound treatment 1102280.0 118000.0 0.58 1143780.0 61200.0 0.36 1390590.0 158045.80645161 0.905206158650914 1.0662 0.9404 2071787 Maybridge1_004594 COC(=O)c1scc(c1N)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I19 compound treatment 894120.0 -89900.0 -0.44 1010160.0 -72400.0 -0.43 1110400.0 -122144.19354839 -0.699579942839575 -0.9062 -0.9727 2071788 Maybridge1_004595 Clc1ccc(CS(=O)(=O)/C(=C/NCc2cccs2)/C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I20 compound treatment 920560.0 -63500.0 -0.31 1124110.0 41500.0 0.25 1133870.0 -98674.1935483899 -0.565155695714475 -0.3628 -0.5256 2071789 Maybridge1_004596 COC(=O)c1sc(SC)c(C(=O)C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I21 compound treatment 1215650.0 232000.0 1.13 1109960.0 27400.0 0.16 1141070.0 -91474.1935483899 -0.523917750281977 0.4448 0.3537 2071790 Maybridge1_004597 Cc1nn(CC#N)c(C)c1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I22 compound treatment 1101800.0 118000.0 0.58 1330790.0 248000.0 1.48 1411320.0 178775.80645161 1.02393707654198 1.7755 0.9413 2071791 Maybridge1_004598 CSc1nn2c(C)cc(C)nc2c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I23 mock treatment 969240.0 -14800.0 -0.07 1273550.0 191000.0 1.14 1279650.0 47105.8064516101 0.269798149445179 0.7696 0.6582 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 I24 mock treatment 1040100.0 56100.0 0.27 1151140.0 68500.0 0.41 1179680.0 -52864.1935483899 -0.302779267900208 0.2187 0.379 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J01 compound treatment 910050.0 -74000.0 -0.36 919460.0 -163000.0 -0.97 926050.0 -306494.19354839 -1.75544317068415 -1.7823 -0.8745 2071792 Maybridge1_004599 CC(C)S(=O)(=O)C/C(=N/OC(=O)c1cc(Cl)cc(Cl)c1)/N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J02 compound treatment 989120.0 5100.0 0.02 1079300.0 -3310.0 -0.02 1163040.0 -69504.1935483899 -0.398084741788647 -0.2268 -0.5679 1594963 Maybridge1_004600 NC(=S)CS(=O)(=O)Cc1ccco1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J03 compound treatment 939420.0 -44600.0 -0.22 1230260.0 148000.0 0.88 1303710.0 71165.8064516101 0.407601617098776 0.6164 0.6213 2071793 Maybridge1_004601 COC(=O)c1scc(c1Cl)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J04 compound treatment 881700.0 -102000.0 -0.5 1146590.0 64000.0 0.38 899680.0 -332864.19354839 -1.90647714583067 -1.1697 -0.5827 1638468 Maybridge1_004602 CCOC(=O)c1sc(SCc2ccccc2)c3C(=O)CC(C)(C)Cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J05 compound treatment 1006590.0 22600.0 0.11 1050970.0 -31600.0 -0.19 1013350.0 -219194.19354839 -1.25543308231512 -0.7698 -0.6041 2071794 Maybridge1_004603 Clc1ccc(cc1)C(=O)O/N=C(\C#N)/S(=O)(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J06 compound treatment 1020530.0 36500.0 0.18 1330890.0 248000.0 1.48 995570.0 -236974.19354839 -1.3572678975637 0.1718 0.0853 1255582 Maybridge1_004604 COC(=O)c1sccc1NS(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J07 compound treatment 741880.0 -242000.0 -1.18 870940.0 -212000.0 -1.26 887730.0 -344814.19354839 -1.97492068026378 -2.55 -0.9719 1569903 Maybridge1_004605 CC(C)S(=O)(=O)c1cnc(nc1N)c2ccccn2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J08 compound treatment 801850.0 -182000.0 -0.89 843360.0 -239000.0 -1.42 865050.0 -367494.19354839 -2.10482020837614 -2.5505 -0.9475 1326008 Maybridge1_004606 CCOC(=O)c1sc(SC)c2C(O)CCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J09 compound treatment 868440.0 -116000.0 -0.56 1081780.0 -826.0 0.0 945510.0 -287034.19354839 -1.64398616816798 -1.278 -0.7352 2071795 Maybridge1_004607 COC(=O)c1scc(c1N/N=C(\C#N)/C(=O)c2ccc(Cl)cc2)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J10 compound treatment 1069020.0 85000.0 0.42 1185980.0 103000.0 0.61 1077440.0 -155104.19354839 -0.888358093041675 0.0818 0.0707 2071796 Maybridge1_004608 CC(=O)c1cc([N+](=O)[O-])c(SCCO)s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J11 compound treatment 963440.0 -20600.0 -0.1 1303710.0 221000.0 1.31 1140290.0 -92254.1935483899 -0.528385194370498 0.396 0.2787 2071797 Maybridge1_004609 COC(=O)c1sc(SC)c(c1N/N=C(\C#N)/S(=O)(=O)C(C)C)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J12 compound treatment 618000.0 -366000.0 -1.79 546770.0 -536000.0 -3.19 750170.0 -482374.19354839 -2.76279453772133 -4.4672 -0.9752 2071798 Maybridge1_004610 COC(=O)c1sc(SC)c2/C(=N\O)/CC(C)(C)Cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J13 compound treatment 1087260.0 103000.0 0.5 1273440.0 191000.0 1.13 1377890.0 145345.80645161 0.832467004901925 1.427 0.9545 2071799 Maybridge1_004611 COC(=O)C(CCSC)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J14 compound treatment 1159120.0 175000.0 0.86 1296860.0 214000.0 1.27 1211840.0 -20704.1935483899 -0.118583111635052 1.161 0.7543 2071800 Maybridge1_004612 CCOC(=O)CSc1sc(C(=O)OCC)c(C)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J15 compound treatment 1035130.0 51100.0 0.25 1255790.0 173000.0 1.03 1092870.0 -139674.19354839 -0.799982884982864 0.2769 0.2085 2071801 Maybridge1_004613 CN(C)/C=C(\C#N)/S(=O)(=O)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J16 compound treatment 848930.0 -135000.0 -0.66 844990.0 -238000.0 -1.41 793120.0 -439424.19354839 -2.51679873823164 -2.6499 -0.895 2071802 Maybridge1_004614 COC(=O)c1cc(c(s1)S(=O)C)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J17 compound treatment 973280.0 -10700.0 -0.05 1065120.0 -17500.0 -0.1 1061440.0 -171104.19354839 -0.979997971780559 -0.6561 -0.6649 2071803 Maybridge1_004615 Cn1c(S)nnc1c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J18 compound treatment 902460.0 -81600.0 -0.4 1138840.0 56200.0 0.33 959120.0 -273424.19354839 -1.56603499631572 -0.9412 -0.5703 2071804 Maybridge1_004616 COC(=O)c1sc2scc(C)c2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J19 compound treatment 1179680.0 196000.0 0.96 1325470.0 243000.0 1.44 1376510.0 143965.80645161 0.824563065360697 1.8618 0.9706 1717909 Maybridge1_004617 NC(=S)CS(=O)(=O)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J20 compound treatment 883420.0 -101000.0 -0.49 1102240.0 19600.0 0.12 1204450.0 -28094.1935483899 -0.160909280627574 -0.3093 -0.5833 1134337 Maybridge1_004618 CCOC(=O)c1sc(SCc2ccccc2)c3C(=O)CCCc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J21 compound treatment 1034290.0 50300.0 0.25 1039360.0 -43200.0 -0.26 1124970.0 -107574.19354839 -0.616130378262979 -0.3624 -0.5094 2071805 Maybridge1_004619 Cc1cc(C)nc(N/C=C(\C#N)/S(=O)(=O)Cc2ccco2)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J22 compound treatment 986930.0 2910.0 0.01 1037030.0 -45600.0 -0.27 1394640.0 162095.80645161 0.928402502956694 0.3877 0.4009 2071806 Maybridge1_004620 Cc1c(/C=N/O)c(=O)n(c2ccccc2)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J23 mock treatment 965840.0 -18200.0 -0.09 1074340.0 -8270.0 -0.05 1360820.0 128275.80645161 0.734698709272379 0.3445 0.4645 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 J24 mock treatment 1032430.0 48400.0 0.24 1189470.0 107000.0 0.64 1217030.0 -15514.1935483899 -0.0888574259691267 0.4521 0.6612 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K01 compound treatment 605650.0 -378000.0 -1.85 644600.0 -438000.0 -2.6 603410.0 -629134.19354839 -3.60336132545374 -4.6515 -0.966 1662640 Maybridge1_004621 O=C(Nc1cc(n[nH]1)c2ccccc2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K02 compound treatment 1012800.0 28800.0 0.14 1118930.0 36300.0 0.22 1199200.0 -33344.1935483899 -0.19097861583877 0.0956 0.2981 2071807 Maybridge1_004622 CCO/C=C(\C#N)/S(=O)(=O)c1ccc2ccccc2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K03 compound treatment 957280.0 -26700.0 -0.13 1074780.0 -7830.0 -0.05 1174400.0 -58144.1935483899 -0.33302042788404 -0.2946 -0.8166 2071808 Maybridge1_004623 Clc1ccc(SCC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K04 compound treatment 932540.0 -51500.0 -0.25 1278000.0 195000.0 1.16 1083380.0 -149164.19354839 -0.854336788059865 0.0324 0.0221 2071809 Maybridge1_004624 O/N=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K05 compound treatment 997370.0 13300.0 0.07 1358560.0 276000.0 1.64 1369320.0 136775.80645161 0.783382394852411 1.4374 0.79 2071810 Maybridge1_004625 COC(=O)c1cscc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K06 compound treatment 996320.0 12300.0 0.06 1391520.0 309000.0 1.84 1301180.0 68635.8064516101 0.39311106127319 1.3222 0.7035 2071811 Maybridge1_004626 O/N=C(/C#N)\S(=O)(=O)c1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K07 compound treatment 917000.0 -67000.0 -0.33 1226050.0 143000.0 0.85 1196100.0 -36444.1935483899 -0.208733842344429 0.1829 0.1952 2071812 Maybridge1_004627 CCO/C=C(\C#N)/S(=O)(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K08 compound treatment 895200.0 -88800.0 -0.43 1025640.0 -57000.0 -0.34 1009370.0 -223174.19354839 -1.27822850215141 -1.1841 -0.8508 2071813 Maybridge1_004628 Nc1cc(n[nH]1)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K09 compound treatment 251880.0 -732000.0 -3.58 251860.0 -831000.0 -4.94 271630.0 -960914.19354839 -5.50362876095292 -8.0949 -0.9854 1194284 Maybridge1_004629 Nc1c(cnc2cc(nn12)c3ccccc3)S(=O)(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K10 compound treatment 905350.0 -78700.0 -0.38 1372550.0 290000.0 1.72 1364480.0 131935.80645161 0.755661331533899 1.2098 0.6297 1948797 Maybridge1_004630 CCOC(=O)c1cnc2cc(nn2c1C)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K11 compound treatment 976690.0 -7330.0 -0.04 1410030.0 327000.0 1.95 1376960.0 144415.80645161 0.827140436950228 1.581 0.7472 2071814 Maybridge1_004631 N/C=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K12 compound treatment 1037850.0 53800.0 0.26 1232700.0 150000.0 0.89 1183680.0 -48864.1935483899 -0.279869298215487 0.5056 0.5203 2071815 Maybridge1_004632 Nc1cscc1S(=O)(=O)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K13 compound treatment 944530.0 -39500.0 -0.19 1293380.0 211000.0 1.25 1297620.0 65075.8064516101 0.372721188253788 0.8274 0.626 1989025 Maybridge1_004633 CCOC(=O)c1cn[nH]c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K14 compound treatment 1060960.0 76900.0 0.38 1338030.0 255000.0 1.52 1095910.0 -136634.19354839 -0.782571308022476 0.6421 0.367 2071816 Maybridge1_004634 CCSc1ncccc1C(=O)NC(CCSC)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K15 compound treatment 934720.0 -49300.0 -0.24 1369210.0 287000.0 1.7 1214720.0 -17824.1935483899 -0.102087933462053 0.786 0.4558 2071817 Maybridge1_004635 CCO/C=C(\C#N)/S(=O)(=O)c1ccc(C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K16 compound treatment 919380.0 -64600.0 -0.32 1438150.0 356000.0 2.11 1105620.0 -126924.19354839 -0.726957356612816 0.6186 0.274 2071818 Maybridge1_004636 CC(C)(C)S(=O)(=O)/C(=C/N1CCCCC1)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K17 compound treatment 1057200.0 73200.0 0.36 1389770.0 307000.0 1.83 1328000.0 95455.8064516101 0.546722408009244 1.5766 0.8128 2071819 Maybridge1_004637 Clc1ccc(CS(=O)(=O)CC#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K18 compound treatment 875200.0 -109000.0 -0.53 1064020.0 -18600.0 -0.11 1090720.0 -141824.19354839 -0.812296993688402 -0.8398 -0.8594 1360241 Maybridge1_004638 COC(=O)C1=C(CSC1)Nc2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K19 compound treatment 903090.0 -80900.0 -0.4 1269400.0 187000.0 1.11 1258530.0 25985.8064516101 0.148833509509853 0.4989 0.4198 2071820 Maybridge1_004639 CN(C)/C=C/1\C(=O)c2ccccc2N(C)S1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K20 compound treatment 821120.0 -163000.0 -0.8 907780.0 -175000.0 -1.04 1041040.0 -191504.19354839 -1.09683881717264 -1.693 -0.9912 2071821 Maybridge1_004640 CSc1scc(c1C#N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K21 compound treatment 1193670.0 210000.0 1.02 1280590.0 198000.0 1.18 1139430.0 -93114.1935483899 -0.533310837852713 0.9632 0.5841 2071822 Maybridge1_004641 COC(=O)c1sc(SC)c(c1N)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K22 compound treatment 1012210.0 28200.0 0.14 1385320.0 303000.0 1.8 1181170.0 -51374.1935483899 -0.29424530419265 0.9489 0.5188 1168939 Maybridge1_004642 CC(C)S(=O)(=O)c1csc(C(=O)O)c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K23 mock treatment 1018240.0 34200.0 0.17 1128880.0 46300.0 0.28 1270250.0 37705.8064516101 0.215959720686085 0.3801 0.9804 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 K24 mock treatment 1054570.0 70500.0 0.34 1124420.0 41800.0 0.25 1311050.0 78505.8064516101 0.449641411470239 0.6022 0.9732 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L01 compound treatment 847200.0 -137000.0 -0.67 953790.0 -129000.0 -0.77 819200.0 -413344.19354839 -2.36742573588726 -2.195 -0.8519 2071823 Maybridge1_004643 Clc1ccc(CSc2cccs2)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L02 compound treatment 332500.0 -652000.0 -3.18 322670.0 -760000.0 -4.52 410580.0 -821964.19354839 -4.70779368902993 -7.1649 -0.9868 2071824 Maybridge1_004644 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)c3cc[nH]n3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L03 compound treatment 862880.0 -121000.0 -0.59 1190410.0 108000.0 0.64 1036320.0 -196224.19354839 -1.12387258140061 -0.6205 -0.4361 2071825 Maybridge1_004645 O=S(=O)(CCSc1cccs1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L04 compound treatment 934720.0 -49300.0 -0.24 1040230.0 -42400.0 -0.25 1038670.0 -193874.19354839 -1.11041297421083 -0.9257 -0.7953 1170462 Maybridge1_004646 CCOC(=O)c1sc(SC)c2c1-c3ccccc3N(C)S2(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L05 compound treatment 720110.0 -264000.0 -1.29 909940.0 -173000.0 -1.03 768450.0 -464094.19354839 -2.65809597626216 -2.8719 -0.9182 2071826 Maybridge1_004647 CS(=O)c1noc(c1C#N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L06 compound treatment 906810.0 -77200.0 -0.38 1040920.0 -41700.0 -0.25 1035080.0 -197464.19354839 -1.13097467200287 -1.0139 -0.8326 2071827 Maybridge1_004648 CSc1sc(C#N)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L07 compound treatment 826340.0 -158000.0 -0.77 1122760.0 40200.0 0.24 1158570.0 -73974.1935483899 -0.423686632911323 -0.5516 -0.6054 2071828 Maybridge1_004649 COC(=O)c1scc(c1N/N=C(\C#N)/C(=O)c2ccccc2)S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L08 compound treatment 701820.0 -282000.0 -1.38 744000.0 -339000.0 -2.01 660190.0 -572354.19354839 -3.27815430577913 -3.8512 -0.9424 1669213 Maybridge1_004650 CCOC(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)CCCc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L09 compound treatment 1041290.0 57300.0 0.28 1247650.0 165000.0 0.98 906110.0 -326434.19354839 -1.86964936956248 -0.3513 -0.1649 2071829 Maybridge1_004651 COC(=O)c1sc(SC)c2C(=O)CC(C)(C)Cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L10 compound treatment 981120.0 -2900.0 -0.01 1262790.0 180000.0 1.07 1256210.0 23665.8064516101 0.135545727092715 0.6887 0.6376 2071830 Maybridge1_004652 O=C1NCCSC1c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L11 compound treatment 922990.0 -61000.0 -0.3 1302250.0 220000.0 1.31 1260750.0 28205.8064516101 0.161548542684873 0.6752 0.5004 1611340 Maybridge1_004653 CC(C)S(=O)(=O)c1cnc(nc1N)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L12 compound treatment 893440.0 -90600.0 -0.44 1410650.0 328000.0 1.95 981440.0 -251104.19354839 -1.43819736547498 0.0404 0.0164 2071831 Maybridge1_004654 CSc1sc(C(=O)NNC(=O)C)c2CCC=Cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L13 compound treatment 749440.0 -235000.0 -1.15 856120.0 -226000.0 -1.35 807710.0 -424834.19354839 -2.43323462380662 -2.8441 -0.9455 2071832 Maybridge1_004655 CS(=O)(=O)c1sc(Cl)c(c1C#N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L14 compound treatment 967200.0 -16800.0 -0.08 1218510.0 136000.0 0.81 1043620.0 -188924.19354839 -1.08206188672599 -0.2056 -0.1519 2071833 Maybridge1_004656 Cc1csc2sc(C(=O)N3CCOCC3)c(C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L15 compound treatment 925120.0 -58900.0 -0.29 1168490.0 85900.0 0.51 1001120.0 -231424.19354839 -1.32548031462615 -0.6366 -0.4392 2071834 Maybridge1_004657 CCOC(=O)c1sc(SC(C)CC)c(C#N)c1c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L16 compound treatment 905950.0 -78100.0 -0.38 1226490.0 144000.0 0.86 1142240.0 -90304.1935483899 -0.517216584149196 -0.0249 -0.0232 2071835 Maybridge1_004658 CCOC(=O)c1sc(SC)c2C(=O)CC(Cc12)c3ccc(C)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L17 compound treatment 899200.0 -84800.0 -0.41 1067140.0 -15500.0 -0.09 1059590.0 -172954.19354839 -0.990593832759742 -0.8643 -0.802 1322824 Maybridge1_004659 COC(=O)c1sc(N2CCOCC2)c(C#N)c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L18 compound treatment 684740.0 -299000.0 -1.46 813510.0 -269000.0 -1.6 804540.0 -428004.19354839 -2.45139077478176 -3.1834 -0.9728 2071836 Maybridge1_004660 CSc1sc(C#N)c(C)c1c2ccn(n2)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L19 compound treatment 1118280.0 134000.0 0.66 1338960.0 256000.0 1.52 1232660.0 115.806451610057 6.63280573920375E-4 1.2592 0.7588 2071837 Maybridge1_004661 [O-][N+](=O)c1cc(ccc1Sc2ccc(Cl)cc2)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L20 compound treatment 1014840.0 30800.0 0.15 1285830.0 203000.0 1.21 1310050.0 77505.8064516101 0.443913919049059 1.0409 0.8031 2071838 Maybridge1_004662 COC(=O)c1sccc1N/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L21 compound treatment 758470.0 -226000.0 -1.1 986030.0 -96600.0 -0.57 1018580.0 -213964.19354839 -1.22547829695234 -1.6753 -0.9599 2071839 Maybridge1_004663 Cn1ncc(C(=O)N)c1[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L22 compound treatment 1013250.0 29200.0 0.14 1163840.0 81200.0 0.48 1063240.0 -169304.19354839 -0.969688485422435 -0.1985 -0.1817 2071840 Maybridge1_004664 Cc1c(/C=N/OC(=O)c2ccc(Cl)cc2)c(=O)n(c3ccccc3)n1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L23 mock treatment 950090.0 -33900.0 -0.17 1147480.0 64900.0 0.39 1096240.0 -136304.19354839 -0.780681235523487 -0.3237 -0.3652 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 L24 mock treatment 910900.0 -73100.0 -0.36 1028280.0 -54300.0 -0.32 1465600.0 233055.80645161 1.33482536516364 0.3779 0.2663 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M01 compound treatment 649790.0 -334000.0 -1.63 685760.0 -397000.0 -2.36 684670.0 -547874.19354839 -3.13794529130864 -4.117 -0.9682 1122245 Maybridge1_004665 Clc1ccc(cc1)C(=O)Nc2cc(n[nH]2)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M02 compound treatment 616800.0 -367000.0 -1.79 723080.0 -360000.0 -2.14 826880.0 -405664.19354839 -2.32343859409259 -3.6117 -0.9945 2071841 Maybridge1_004666 CSc1[nH]nc(c1C#N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M03 compound treatment 666280.0 -318000.0 -1.55 948440.0 -134000.0 -0.8 828990.0 -403554.19354839 -2.3113535850839 -2.6914 -0.9292 2071842 Maybridge1_004667 Fc1cccc(Cl)c1CN/C(=C(\NCc2cccs2)/C#N)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M04 compound treatment 896800.0 -87200.0 -0.43 1230140.0 148000.0 0.88 1165980.0 -66564.1935483899 -0.381245914070378 0.0404 0.0385 2071843 Maybridge1_004668 O/N=C(\C#N)/S(=O)(=O)c1ccccc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M05 compound treatment 888000.0 -96000.0 -0.47 1416260.0 334000.0 1.98 1089930.0 -142614.19354839 -0.816821712701134 0.4031 0.1835 2071844 Maybridge1_004669 CCOC(=O)c1nnc2cc(C)nn2c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M06 compound treatment 986620.0 2600.0 0.01 1300120.0 218000.0 1.29 1060830.0 -171714.19354839 -0.983491742157479 0.1863 0.1146 1023037 Maybridge1_004670 Clc1cccc(c1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M07 compound treatment 875610.0 -108000.0 -0.53 1309860.0 227000.0 1.35 1416320.0 183775.80645161 1.05257453864788 1.0821 0.6035 2071845 Maybridge1_004671 Cc1cc2nc3CSCc3c(O)n2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M08 compound treatment 916640.0 -67400.0 -0.33 1329340.0 247000.0 1.47 1359860.0 127315.80645161 0.729200316548046 1.078 0.6451 2071846 Maybridge1_004672 Cc1cc2ncc(C(=O)O)c(C)n2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M09 compound treatment 873480.0 -111000.0 -0.54 1425630.0 343000.0 2.04 1416870.0 184325.80645161 1.05572465947953 1.4754 0.6253 1917986 Maybridge1_004673 CCOC(=O)c1[nH]c(C)c(/C(=N/O)/C)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M10 compound treatment 958490.0 -25500.0 -0.12 1486400.0 404000.0 2.4 1094490.0 -138054.19354839 -0.790704347260552 0.8578 0.3389 2071847 Maybridge1_004674 CCOC(=O)c1cnc2cc(nn2c1C)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M11 compound treatment 918740.0 -65300.0 -0.32 1230440.0 148000.0 0.88 1067490.0 -165054.19354839 -0.945346642632419 -0.2224 -0.1672 2071848 Maybridge1_004675 Cc1ccc(cc1)S(=O)(=O)CCN(CCS(=O)(=O)c2ccc(C)cc2)c3ncccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M12 compound treatment 809490.0 -175000.0 -0.85 947230.0 -135000.0 -0.81 1211680.0 -20864.1935483899 -0.119499510422441 -1.0261 -0.8705 2071849 Maybridge1_004676 CSc1nc(C)nc(C2CC2)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M13 compound treatment 937440.0 -46600.0 -0.23 1296670.0 214000.0 1.27 1169570.0 -62974.1935483899 -0.36068421627834 0.3953 0.2944 1147922 Maybridge1_004677 CN(C)C(=O)Oc1cc(C)c2c(C)nn(C)c2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M14 compound treatment 946000.0 -38000.0 -0.19 1361640.0 279000.0 1.66 1349860.0 117315.80645161 0.671925392336244 1.2387 0.6882 2071850 Maybridge1_004678 CC(C)(C)S(=O)(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M15 compound treatment 882080.0 -102000.0 -0.5 969780.0 -113000.0 -0.67 1005290.0 -227254.19354839 -1.30159667122983 -1.4264 -0.9222 2071851 Maybridge1_004679 COC(=O)c1ccccc1SCC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M16 compound treatment 951880.0 -32100.0 -0.16 1378880.0 296000.0 1.76 1502360.0 269815.80645161 1.54536798656623 1.8187 0.7743 2071852 Maybridge1_004680 CCO/C=C(\C#N)/S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M17 compound treatment 868480.0 -116000.0 -0.56 1131650.0 49000.0 0.29 1115520.0 -117024.19354839 -0.670255181643132 -0.5445 -0.5896 2071853 Maybridge1_004681 Cc1nn(c(C)c1[N+](=O)[O-])S(=O)(=O)c2ccc(Cl)s2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M18 compound treatment 855200.0 -129000.0 -0.63 1353600.0 271000.0 1.61 1144920.0 -87624.1935483899 -0.501866904460433 0.2773 0.1539 2071854 Maybridge1_004682 COC(=O)c1scc(c1n2cccc2)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M19 compound treatment 977370.0 -6650.0 -0.03 1095850.0 13200.0 0.08 1329250.0 96705.8064516101 0.553881773535719 0.3465 0.6183 2071855 Maybridge1_004683 Cc1cc2nnc(C(=O)O)c(C)n2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M20 compound treatment 1000320.0 16300.0 0.08 1304970.0 222000.0 1.32 1198880.0 -33664.1935483899 -0.192811413413548 0.6981 0.5215 1303068 Maybridge1_004684 Cc1c(cnc2cc(nn12)C(C)(C)C)S(=O)(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M21 compound treatment 1009760.0 25700.0 0.13 1300520.0 218000.0 1.3 1306050.0 73505.8064516101 0.421003949364338 1.0638 0.7775 2071856 Maybridge1_004685 CC(=O)CS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M22 compound treatment 1201890.0 218000.0 1.06 1245920.0 163000.0 0.97 1329760.0 97215.8064516101 0.556802794670521 1.4967 0.9689 1428823 Maybridge1_004686 CCOC(=O)c1c[nH]c2cc(C)nn2c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M23 mock treatment 910820.0 -73200.0 -0.36 1075920.0 -6690.0 -0.04 1134020.0 -98524.1935483899 -0.564296571851298 -0.5552 -0.8296 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 M24 mock treatment 882720.0 -101000.0 -0.49 1033280.0 -49300.0 -0.29 1324830.0 92285.8064516101 0.528566257034102 -0.1499 -0.1919 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N01 compound treatment 798780.0 -185000.0 -0.91 928060.0 -155000.0 -0.92 787900.0 -444644.19354839 -2.5466962486702 -2.5235 -0.884 2071857 Maybridge1_004687 Clc1cccc(Cl)c1/C=C(\C#N)/S(=O)(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N02 compound treatment 904350.0 -79700.0 -0.39 1109320.0 26700.0 0.16 1089760.0 -142784.19354839 -0.817795386412735 -0.6052 -0.6581 2071858 Maybridge1_004688 CSc1ccc(cc1c2cc[nH]n2)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N03 compound treatment 835360.0 -149000.0 -0.73 1145310.0 62700.0 0.37 1191680.0 -40864.1935483899 -0.234049358846046 -0.3392 -0.3994 2071859 Maybridge1_004689 OC(=O)c1cccc(CSc2cccs2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N04 compound treatment 779560.0 -204000.0 -1.0 1083790.0 1180.0 0.01 980130.0 -252414.19354839 -1.44570038054672 -1.4074 -0.8009 2071860 Maybridge1_004690 CCCCSc1sc(C(=O)OCC)c2CCCC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N05 compound treatment 924060.0 -60000.0 -0.29 1225540.0 143000.0 0.85 1144710.0 -87834.1935483899 -0.503069677868881 0.0311 0.0302 2071861 Maybridge1_004691 O=C(O/N=C(\C#N)/S(=O)(=O)c1cccs1)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N06 compound treatment 901280.0 -82700.0 -0.4 1307380.0 225000.0 1.34 1147810.0 -84734.1935483899 -0.485314451363222 0.2581 0.1746 2071862 Maybridge1_004692 CC1(C)CC(=O)c2c(SCc3ccc(Cl)cc3)sc(C#N)c2C1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N07 compound treatment 984850.0 828.0 0.0 1352210.0 270000.0 1.6 1365880.0 133335.80645161 0.763679820923551 1.3689 0.7708 1258455 Maybridge1_004693 CC(C)S(=O)(=O)c1cnc(nc1N)N2CCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N08 compound treatment 848800.0 -135000.0 -0.66 1188610.0 106000.0 0.63 1183310.0 -49234.1935483899 -0.281988470411324 -0.1803 -0.1887 2071863 Maybridge1_004694 O=S(=O)(Cc1ccco1)C(=C2SCCS2)C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N09 compound treatment 897190.0 -86800.0 -0.42 1312650.0 230000.0 1.37 1361120.0 128575.80645161 0.736416956998733 0.97 0.6023 2071864 Maybridge1_004695 COc1ccc(cc1)c2c(C#N)c(SC)sc2C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N10 compound treatment 934820.0 -49200.0 -0.24 1351410.0 269000.0 1.6 1202650.0 -29894.1935483899 -0.171218766985698 0.6852 0.4216 2071865 Maybridge1_004696 CSc1sc(C(=O)C)c(N)c1C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N11 compound treatment 946300.0 -37700.0 -0.18 1342310.0 260000.0 1.54 1400010.0 167465.80645161 0.959159137258432 1.339 0.7328 1517019 Maybridge1_004697 CC(C)(C)S(=O)(=O)c1cnc(nc1N)N2CCCCC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N12 compound treatment 987490.0 3470.0 0.02 1334890.0 252000.0 1.5 1246920.0 14375.8064516101 0.0823373224999505 0.9235 0.6146 2071866 Maybridge1_004698 Nc1c(C#N)sc2sc(C#N)c(c3ccc(Cl)cc3)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N13 compound treatment 1059900.0 75900.0 0.37 1333390.0 251000.0 1.49 1299120.0 66575.8064516101 0.381312426885559 1.2952 0.818 2071867 Maybridge1_004699 CSc1sc(C(=O)O)c(Cl)c1S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N14 compound treatment 958890.0 -25100.0 -0.12 1316890.0 234000.0 1.39 1316440.0 83895.8064516101 0.4805125956204 1.0109 0.6836 1183735 Maybridge1_004700 CSc1sc(C(=O)OCc2ccccc2)c3CC(C)(C)CC(=O)c13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N15 compound treatment 909350.0 -74700.0 -0.36 1148350.0 65700.0 0.39 1386520.0 153975.80645161 0.881895264496711 0.5242 0.5083 2071868 Maybridge1_004701 CCC(C)Sc1sc(C(=O)O)c(c1C#N)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N16 compound treatment 222520.0 -762000.0 -3.72 456400.0 -626000.0 -3.72 478640.0 -753904.19354839 -4.3179805548444 -6.791 -0.9974 2071869 Maybridge1_004702 N/C(=C(/N=C/c1ccccc1Sc2ccc(Cl)cc2)\C#N)/C#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N17 compound treatment 935710.0 -48300.0 -0.24 1277620.0 195000.0 1.16 1244840.0 12295.8064516101 0.0704241382638956 0.5739 0.4841 2071870 Maybridge1_004703 CNC(=S)NNC(=O)Cn1nc(C)c(Br)c1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N18 compound treatment 975530.0 -8490.0 -0.04 1315410.0 233000.0 1.38 1228320.0 -4224.19354838994 -0.0241940365340018 0.7614 0.5496 2071871 Maybridge1_004704 COC(=O)c1sccc1N/N=C(\C#N)/C(=O)c2cccs2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N19 compound treatment 975210.0 -8810.0 -0.04 1250910.0 168000.0 1.0 1282080.0 49535.8064516101 0.283715956028647 0.7168 0.6884 2071872 Maybridge1_004705 CSc1n[nH]c(N)c1S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N20 compound treatment 970620.0 -13400.0 -0.07 1384830.0 302000.0 1.8 1287560.0 55015.8064516101 0.315102614496715 1.1817 0.6472 2071873 Maybridge1_004706 CC(=O)OCc1ccc(/C=C(\C#N)/S(=O)(=O)c2cccs2)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N21 compound treatment 918910.0 -65100.0 -0.32 1219090.0 136000.0 0.81 1306010.0 73465.8064516101 0.42077484966749 0.5278 0.5453 2071874 Maybridge1_004707 Cc1nc(no1)c2cccc(CSc3nnc(n3C)C(F)(F)F)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N22 compound treatment 895630.0 -88400.0 -0.43 991890.0 -90700.0 -0.54 1104870.0 -127674.19354839 -0.731252975928702 -0.983 -0.977 2071875 Maybridge1_004708 CS(=O)c1sc(C#N)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N23 mock treatment 1012110.0 28100.0 0.14 1232260.0 150000.0 0.89 1299910.0 67365.8064516101 0.385837145898291 0.8158 0.8328 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 N24 mock treatment 862120.0 -122000.0 -0.6 1007520.0 -75100.0 -0.45 1224680.0 -7864.19354838994 -0.0450421089470979 -0.6277 -0.8417 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O01 compound treatment 533050.0 -451000.0 -2.2 589760.0 -493000.0 -2.93 601780.0 -630764.19354839 -3.61269713810026 -5.05 -0.9811 1610946 Maybridge1_004709 Clc1ccc(cc1)C(=O)Nc2[nH]nc(c2Br)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O02 compound treatment 1016180.0 32200.0 0.16 1210660.0 128000.0 0.76 1196840.0 -35704.1935483899 -0.204495497952756 0.4123 0.5128 2071876 Maybridge1_004710 O=S(=O)(CC#N)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O03 compound treatment 908510.0 -75500.0 -0.37 1081940.0 -666.0 0.0 1387840.0 155295.80645161 0.889455554492669 0.2982 0.3097 2071877 Maybridge1_004711 Cc1cc(O)n2nc(c(Br)c2n1)c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O04 compound treatment 709330.0 -275000.0 -1.34 958450.0 -124000.0 -0.74 831570.0 -400974.19354839 -2.29657665463726 -2.527 -0.9154 2071878 Maybridge1_004712 Cc1c(csc1C(=O)NN)S(=O)(=O)c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O05 compound treatment 920090.0 -63900.0 -0.31 1193250.0 111000.0 0.66 1119930.0 -112614.19354839 -0.644996940065727 -0.1729 -0.1777 2071879 Maybridge1_004713 COc1cscc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O06 compound treatment 917050.0 -67000.0 -0.33 1188360.0 106000.0 0.63 1221920.0 -10624.1935483899 -0.0608499880295553 0.139 0.1954 2071880 Maybridge1_004714 Cc1ccc(cc1)C(=O)CC#N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O07 compound treatment 902320.0 -81700.0 -0.4 1286610.0 204000.0 1.21 1400610.0 168065.80645161 0.96259563271114 1.0257 0.6414 2071881 Maybridge1_004715 CN1c2ccccc2C(=O)/C(=N\Nc3ccccc3F)/S1(=O)=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O08 compound treatment 864290.0 -120000.0 -0.58 1184500.0 102000.0 0.61 1080910.0 -151634.19354839 -0.86848369434018 -0.4893 -0.4045 2071882 Maybridge1_004716 N/C(=N\O)/c1cccc(CS(=O)(=O)c2ccccn2)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O09 compound treatment 771470.0 -213000.0 -1.04 1149030.0 66400.0 0.39 1135880.0 -96664.1935483899 -0.553643435947903 -0.6912 -0.5568 2071883 Maybridge1_004717 Fc1ccc(N/C(=C\C#N)/c2ccccc2Cl)c(F)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O10 compound treatment 1072320.0 88300.0 0.43 1292520.0 210000.0 1.25 1391010.0 158465.80645161 0.90761170546781 1.4938 0.9321 1586034 Maybridge1_004718 CCOC(=O)c1cnc2cc(nn2c1C)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O11 compound treatment 857660.0 -126000.0 -0.62 1257460.0 175000.0 1.04 1407710.0 175165.80645161 1.00326082890152 0.8231 0.5239 1435418 Maybridge1_004719 Cc1ccc(cc1)S(=O)(=O)CCN2CCN(CCS(=O)(=O)c3ccc(C)cc3)CC2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O12 compound treatment 1128050.0 144000.0 0.7 1346530.0 264000.0 1.57 1290080.0 57535.8064516101 0.329535895398089 1.5027 0.858 2071884 Maybridge1_004720 OCCSCCS(=O)(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O13 compound treatment 821040.0 -163000.0 -0.8 1004740.0 -77900.0 -0.46 921120.0 -311424.19354839 -1.78367970832057 -1.7569 -0.8752 2071885 Maybridge1_004721 CSc1nc(N)n2nc(C)cc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O14 compound treatment 998560.0 14500.0 0.07 1342570.0 260000.0 1.55 1157870.0 -74674.1935483899 -0.427695877606149 0.6866 0.4276 1329939 Maybridge1_004722 COc1ncccc1C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O15 compound treatment 882850.0 -101000.0 -0.49 1070450.0 -12200.0 -0.07 1151970.0 -80574.1935483899 -0.461488082891113 -0.5936 -0.8728 2071886 Maybridge1_004723 CCOC(=O)/C(=N\Nc1ccc(F)cc1F)/C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O16 compound treatment 755460.0 -229000.0 -1.12 1078930.0 -3680.0 -0.02 1195420.0 -37124.1935483899 -0.212628537190831 -0.7801 -0.6861 1061097 Maybridge1_004724 Cc1cc(C)c2ccc(N)nc2n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O17 compound treatment 812010.0 -172000.0 -0.84 1050830.0 -31800.0 -0.19 1135290.0 -97254.1935483899 -0.557022656476399 -0.9159 -0.8929 2071887 Maybridge1_004725 COc1sc(/C=N/O)cc1Br 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O18 compound treatment 896410.0 -87600.0 -0.43 1031360.0 -51200.0 -0.3 1178130.0 -54414.1935483899 -0.311656881153038 -0.603 -0.9871 2071888 Maybridge1_004726 COC(=O)c1scc(c1Cl)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O19 compound treatment 997870.0 13800.0 0.07 1183470.0 101000.0 0.6 1090990.0 -141554.19354839 -0.810750570734683 -0.0827 -0.0819 2071889 Maybridge1_004727 O=S(=O)(CC#N)c1ccccn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O20 compound treatment 893030.0 -91000.0 -0.44 1064600.0 -18000.0 -0.11 1145000.0 -87544.1935483899 -0.501408705066739 -0.608 -0.8959 1521014 Maybridge1_004728 Clc1ccc(cc1)c2cc3ncc(cn3n2)S(=O)(=O)c4ccc(Cl)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O21 compound treatment 933190.0 -50800.0 -0.25 1057440.0 -25200.0 -0.15 1123650.0 -108894.19354839 -0.623690668258937 -0.5899 -0.8576 2071890 Maybridge1_004729 COC(=O)c1sc(SC)c(C#N)c1c2ccc(Cl)cc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O22 compound treatment 927940.0 -56100.0 -0.27 970810.0 -112000.0 -0.66 1090650.0 -141894.19354839 -0.812697918157884 -1.0112 -0.9319 1278022 Maybridge1_004730 CCOC(=O)c1cnc2n(C)nc(C)c2c1Sc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O23 mock treatment 1023570.0 39500.0 0.19 1198650.0 116000.0 0.69 1379850.0 147305.80645161 0.843692890047439 0.9971 0.9007 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 O24 mock treatment 893940.0 -90100.0 -0.44 996580.0 -86000.0 -0.51 1189800.0 -42744.1935483899 -0.244817044597864 -0.6908 -0.9623 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P01 compound treatment 914240.0 -69800.0 -0.34 967120.0 -115000.0 -0.69 958750.0 -273794.19354839 -1.56815416851156 -1.4987 -0.8586 2071891 Maybridge1_004731 N/C(=N\O)/CS(=O)(=O)c1cccs1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P02 compound treatment 961210.0 -22800.0 -0.11 1032660.0 -49900.0 -0.3 1047650.0 -184894.19354839 -1.05898009226863 -0.8472 -0.7664 2071892 Maybridge1_004732 Brc1ccc(s1)c2cc[nH]n2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P03 compound treatment 945020.0 -39000.0 -0.19 1076640.0 -5970.0 -0.04 949640.0 -282904.19354839 -1.62033162446851 -1.066 -0.6532 2071893 Maybridge1_004733 Cc1cc(nc2c([N+](=O)[O-])c(nn12)C(C)(C)C)C(F)(F)F 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P04 compound treatment 683360.0 -301000.0 -1.47 871300.0 -211000.0 -1.26 907840.0 -324704.19354839 -1.85974080767384 -2.6473 -0.9869 1542166 Maybridge1_004734 CCOC(=O)c1sc(SC(C)C)c2C(=O)CCCc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P05 compound treatment 979380.0 -4640.0 -0.02 1112750.0 30100.0 0.18 1210200.0 -22344.1935483899 -0.127976199205788 0.0165 0.0746 2071894 Maybridge1_004735 CC1(C)OC(=O)C(=CNc2ccc(F)c(Cl)c2)C(=O)O1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P06 compound treatment 973920.0 -10100.0 -0.05 1117050.0 34400.0 0.2 1042150.0 -190394.19354839 -1.09048130058513 -0.5398 -0.4861 2071895 Maybridge1_004736 CSc1sc(C(=O)/C=C/N(C)C)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P07 compound treatment 34440.0 -950000.0 -4.64 39320.0 -1040000.0 -6.2 39200.0 -1193344.19354839 -6.83486982440784 -10.2066 -0.988 2071896 Maybridge1_004737 CSC(=C(C#N)S(=O)(=O)C(C)C)SC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P08 compound treatment 847520.0 -137000.0 -0.67 1211460.0 129000.0 0.77 1177920.0 -54624.1935483899 -0.312859654561486 -0.1233 -0.116 2071897 Maybridge1_004738 CCOC(=O)c1sc(SC)c(C#N)c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P09 compound treatment 994430.0 10400.0 0.05 1266820.0 184000.0 1.1 1167470.0 -65074.1935483899 -0.372711950362819 0.4466 0.3856 1253540 Maybridge1_004739 CCCS(=O)(=O)c1cnc(C)nc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P10 compound treatment 853490.0 -131000.0 -0.64 1161970.0 79400.0 0.47 1139710.0 -92834.1935483899 -0.531707139974782 -0.4027 -0.4217 2071898 Maybridge1_004740 Cc1c(sc2sc(C(=O)O)c(C)c12)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P11 compound treatment 26980.0 -957000.0 -4.68 30160.0 -1050000.0 -6.26 32980.0 -1199564.19354839 -6.87049482726758 -10.2796 -0.9881 1012008 Maybridge1_004741 CN(C)CCC(=O)c1ccc(Cl)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P12 compound treatment 969040.0 -15000.0 -0.07 1124800.0 42200.0 0.25 1226490.0 -6054.19354838994 -0.0346753476647617 0.0826 0.3132 2071899 Maybridge1_004742 Cc1csc2sc(CO)c(C)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P13 compound treatment 1018940.0 34900.0 0.17 1184910.0 102000.0 0.61 1068730.0 -163814.19354839 -0.938244552030155 -0.092 -0.0813 2071900 Maybridge1_004743 CSc1sc(C(=O)O)c(C)c1C(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P14 compound treatment 960400.0 -23600.0 -0.12 987720.0 -94900.0 -0.56 1004800.0 -227744.19354839 -1.30440314251621 -1.1455 -0.8034 1410702 Maybridge1_004744 CSc1sc(C(=O)OCC=C)c2CC(C)(C)CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P15 compound treatment 961280.0 -22700.0 -0.11 1074740.0 -7870.0 -0.05 1045340.0 -187204.19354839 -1.07221059976156 -0.7102 -0.6582 2071901 Maybridge1_004745 CSc1sc(Br)c(Cl)c1S(=O)(=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P16 compound treatment 896560.0 -87500.0 -0.43 1037970.0 -44600.0 -0.27 1214910.0 -17634.1935483899 -0.100999709902029 -0.4583 -0.8932 1123577 Maybridge1_004746 CCOC(=O)CC1Sc2ccccc2NC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P17 compound treatment 954670.0 -29400.0 -0.14 1114830.0 32200.0 0.19 1026200.0 -206344.19354839 -1.18183480470295 -0.6545 -0.5428 1646261 Maybridge1_004747 COC(=O)c1sc(N2CCCCC2)c(C#N)c1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P18 compound treatment 907950.0 -76100.0 -0.37 1083280.0 674.0 0.0 1234150.0 1605.80645161006 0.00919724428147892 -0.207 -0.5566 2071902 Maybridge1_004748 COC(=O)c1sccc1N/N=C(\C#N)/C(=O)c2ccco2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P19 compound treatment 895220.0 -88800.0 -0.43 1012170.0 -70400.0 -0.42 899710.0 -332834.19354839 -1.90630532105804 -1.5929 -0.7967 1280343 Maybridge1_004749 Cc1ccc(cc1)S(=O)(=O)N=S2(=O)CCCS(=O)(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P20 compound treatment 959090.0 -24900.0 -0.12 1137940.0 55300.0 0.33 1098030.0 -134514.19354839 -0.770429024089574 -0.3252 -0.3841 2071903 Maybridge1_004750 CC(=O)OCc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)o1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P21 compound treatment 926160.0 -57900.0 -0.28 1101000.0 18400.0 0.11 1129620.0 -102924.19354839 -0.589497538504491 -0.4404 -0.6644 2071904 Maybridge1_004751 CC(C)(C)OC(=O)NC(CC(=O)N)C(=O)Oc1ccc(cc1)[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P22 compound treatment 28080.0 -956000.0 -4.67 26750.0 -1060000.0 -6.28 29600.0 -1202944.19354839 -6.88985375165117 -10.2994 -0.9878 2071905 Maybridge1_004752 CC1(C)CC(=O)c2c(sc(C#N)c2C1)S(=O)(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P23 mock treatment 1009280.0 25300.0 0.12 1194360.0 112000.0 0.66 1175910.0 -56634.1935483899 -0.324371914328058 0.2677 0.357 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.554 P24 mock treatment 975240.0 -8780.0 -0.04 1027610.0 -55000.0 -0.33 1108660.0 -123884.19354839 -0.709545779652428 -0.6232 -0.7965 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A01 compound treatment 843490.0 -270000.0 -1.32 951360.0 -164000.0 -0.97 924500.0 -143048.77118644 -0.81931075282948 -1.7975 -0.9802 338 Bio1_000353 Nc1ccncc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A02 compound treatment 886950.0 -227000.0 -1.11 941680.0 -173000.0 -1.03 1018420.0 -49128.77118644 -0.281384664632233 -1.3976 -0.9077 339 Bio1_000354 CO[C@H](C/C=C\C=C\CC/C=C/C[C@H](C)\C=C\C(=C/C(=O)O)\CC(=O)O)\C(=C/C=C(\C)/C(=O)O)\C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A03 compound treatment 895160.0 -219000.0 -1.07 921400.0 -194000.0 -1.15 925680.0 -141868.77118644 -0.812552311772488 -1.7507 -0.99 340 Bio1_000355 CCCCCC(O)CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A04 compound treatment 912710.0 -201000.0 -0.98 952970.0 -162000.0 -0.96 831360.0 -236188.77118644 -1.35276939693821 -1.9047 -0.987 341 Bio1_000356 N[C@@H](Cn1ccc(=O)c(O)c1)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A05 compound treatment 953520.0 -160000.0 -0.78 953920.0 -161000.0 -0.96 889520.0 -178028.77118644 -1.01965843772237 -1.594 -0.9941 1000040 Bio1_000357 [N-2]C1(CC2CC3CC(C2)C1)C3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A06 compound treatment 1012440.0 -101000.0 -0.5 1040560.0 -74500.0 -0.44 890410.0 -177138.77118644 -1.01456096946751 -1.1274 -0.9296 3000159 Bio1_000358 [Li].[Cl] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A07 compound treatment 959330.0 -154000.0 -0.75 1024320.0 -90700.0 -0.54 915060.0 -152488.77118644 -0.873378281285422 -1.2514 -0.9822 1000042 Bio1_000359 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A08 compound treatment 950720.0 -163000.0 -0.8 1044280.0 -70800.0 -0.42 951970.0 -115578.77118644 -0.661976536019659 -1.0852 -0.9706 Bio1_000360 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A09 compound treatment 39950.0 -1070000.0 -5.25 1029160.0 -85900.0 -0.51 900670.0 -166878.77118644 -0.955796897226205 -3.8758 -0.7235 3103678 Bio1_000361 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A10 mock treatment 1002820.0 -111000.0 -0.54 1148800.0 33700.0 0.2 1024410.0 -43138.77118644 -0.247076985029363 -0.3398 -0.5405 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A11 mock treatment 958790.0 -155000.0 -0.76 1082670.0 -32400.0 -0.19 911160.0 -156388.77118644 -0.895715501728025 -1.0655 -0.8964 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A12 mock treatment 1006040.0 -108000.0 -0.53 1148910.0 33900.0 0.2 966520.0 -101028.77118644 -0.578641521291487 -0.5218 -0.646 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A13 mock treatment 998370.0 -115000.0 -0.56 1130080.0 15000.0 0.09 981290.0 -86258.77118644 -0.494046458230655 -0.5592 -0.7407 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A14 mock treatment 1066030.0 -47700.0 -0.23 1025660.0 -89400.0 -0.53 891230.0 -176318.77118644 -1.00986442568215 -1.0247 -0.8797 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A15 mock treatment 912480.0 -201000.0 -0.98 1093440.0 -21600.0 -0.13 952200.0 -115348.77118644 -0.660659212762788 -1.0235 -0.8588 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A16 mock treatment 1014300.0 -99500.0 -0.49 1106490.0 -8570.0 -0.05 915680.0 -151868.77118644 -0.86982723598429 -0.8122 -0.8141 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A17 mock treatment 949680.0 -164000.0 -0.8 1090880.0 -24200.0 -0.14 878880.0 -188668.77118644 -1.08059895708372 -1.1698 -0.8645 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A18 mock treatment 950030.0 -164000.0 -0.8 1188640.0 73600.0 0.44 895400.0 -172148.77118644 -0.985980782285825 -0.7785 -0.5797 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A19 mock treatment 1057410.0 -56400.0 -0.28 1061330.0 -53700.0 -0.32 898740.0 -168808.77118644 -0.966850957599083 -0.9017 -0.8548 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A20 mock treatment 1009790.0 -104000.0 -0.51 1095040.0 -20000.0 -0.12 938440.0 -129108.77118644 -0.739469508478228 -0.789 -0.8718 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A21 mock treatment 914020.0 -200000.0 -0.98 1022590.0 -92500.0 -0.55 888020.0 -179528.77118644 -1.02824967635414 -1.4746 -0.9698 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A22 mock treatment 936060.0 -178000.0 -0.87 958150.0 -157000.0 -0.93 878150.0 -189398.77118644 -1.08478002655118 -1.6663 -0.9956 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A23 mock treatment 917550.0 -196000.0 -0.96 990800.0 -124000.0 -0.74 871250.0 -196298.77118644 -1.12429972425733 -1.6293 -0.9862 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 A24 mock treatment 909000.0 -205000.0 -1.0 1017970.0 -97100.0 -0.58 862360.0 -205188.77118644 -1.17521713188162 -1.5895 -0.9646 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B01 compound treatment 631200.0 -483000.0 -2.36 703850.0 -411000.0 -2.45 717180.0 -350368.77118644 -2.00673448158857 -3.9316 -0.9965 1000045 Bio1_000362 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B02 compound treatment 1030080.0 -83700.0 -0.41 1033920.0 -81100.0 -0.48 997230.0 -70318.77118644 -0.402750229037042 -0.7472 -0.9965 347 Bio1_000363 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B03 compound treatment 79200.0 -1030000.0 -5.05 256530.0 -859000.0 -5.11 485760.0 -581788.77118644 -3.3321907776981 -7.7898 -0.9836 348 Bio1_000364 COc1ccc2[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CCc2c1)NCCCCCCN5C(=O)C=CC5=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B04 compound treatment 147170.0 -967000.0 -4.72 223490.0 -892000.0 -5.3 198810.0 -868738.77118644 -4.97569472795576 -8.6603 -0.9989 349 Bio1_000365 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B05 compound treatment 343920.0 -770000.0 -3.76 416800.0 -698000.0 -4.15 373090.0 -694458.77118644 -3.97750734879247 -6.8654 -0.9992 350 Bio1_000366 CC[C@]1(O)C[C@H]2CN(C1)CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@H]7[C@@]86CCN9CC=C[C@](CC)([C@H]98)[C@@H](C(=O)OC)[C@]7(O)C(=O)OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B06 compound treatment 719150.0 -395000.0 -1.93 898410.0 -217000.0 -1.29 727690.0 -339858.77118644 -1.94653853624196 -2.9808 -0.9846 351 Bio1_000367 CC(C)NCC(O)COc1cccc2ccccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B07 compound treatment 1067640.0 -46100.0 -0.23 1076480.0 -38600.0 -0.23 1047560.0 -19988.77118644 -0.114485535479041 -0.3287 -0.9628 352 Bio1_000368 CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc(O)cc3)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B08 compound treatment 557120.0 -557000.0 -2.72 632810.0 -482000.0 -2.87 549980.0 -517568.77118644 -2.9643712144099 -4.9374 -0.9994 353 Bio1_000369 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B09 compound treatment 1073330.0 -40400.0 -0.2 1100800.0 -14300.0 -0.08 922500.0 -145048.77118644 -0.830765737671841 -0.6427 -0.7489 354 Bio1_000370 Nc1ccc2C(=O)NC(=O)c3cccc1c32 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B10 mock treatment 1012640.0 -101000.0 -0.49 1009280.0 -106000.0 -0.63 984130.0 -83418.77118644 -0.477780379754503 -0.9243 -0.992 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B11 mock treatment 1048370.0 -65400.0 -0.32 1130420.0 15400.0 0.09 930580.0 -136968.77118644 -0.784487598908705 -0.5847 -0.6863 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B12 mock treatment 1103010.0 -10800.0 -0.05 1143040.0 28000.0 0.17 940120.0 -127428.77118644 -0.729847321210645 -0.3557 -0.474 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B13 mock treatment 1205090.0 91300.0 0.45 1073500.0 -41600.0 -0.25 1000970.0 -66578.77118644 -0.381329407381828 -0.1053 -0.1653 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B14 mock treatment 1022900.0 -90900.0 -0.44 1189280.0 74200.0 0.44 935620.0 -131928.77118644 -0.755621037105956 -0.4378 -0.4461 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B15 mock treatment 993630.0 -120000.0 -0.59 1138030.0 23000.0 0.14 972910.0 -94638.77118644 -0.542042844720145 -0.573 -0.7069 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B16 mock treatment 1079060.0 -34700.0 -0.17 1165450.0 50400.0 0.3 933770.0 -133778.77118644 -0.76621689808514 -0.3673 -0.4373 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B17 mock treatment 1059600.0 -54200.0 -0.26 1077090.0 -38000.0 -0.23 950100.0 -117448.77118644 -0.672686946847266 -0.6716 -0.8867 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B18 mock treatment 1133200.0 19400.0 0.09 1033670.0 -81400.0 -0.48 933800.0 -133748.77118644 -0.766045073312504 -0.6669 -0.732 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B19 mock treatment 1103680.0 -10100.0 -0.05 1114240.0 -818.0 0.0 1059160.0 -8388.77118644002 -0.0480466233933503 -0.059 -0.8551 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B20 mock treatment 1093800.0 -20000.0 -0.1 1131580.0 16500.0 0.1 1011460.0 -56088.77118644 -0.321248011883647 -0.1851 -0.5291 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B21 mock treatment 1107640.0 -6140.0 -0.03 1032960.0 -82100.0 -0.49 899440.0 -168108.77118644 -0.962841712904257 -0.8551 -0.7918 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B22 mock treatment 999070.0 -115000.0 -0.56 1058080.0 -57000.0 -0.34 850630.0 -216918.77118644 -1.24240061798206 -1.2365 -0.8804 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B23 mock treatment 1080120.0 -33700.0 -0.16 1094590.0 -20500.0 -0.12 1007870.0 -59678.77118644 -0.341809709675684 -0.3626 -0.9101 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 B24 mock treatment 1059200.0 -54600.0 -0.27 1113660.0 -1400.0 -0.01 877960.0 -189588.77118644 -1.08586825011121 -0.7857 -0.7027 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C01 compound treatment 982050.0 -132000.0 -0.64 1096000.0 -19100.0 -0.11 918560.0 -148988.77118644 -0.853332057811291 -0.9297 -0.865 355 Bio1_000371 COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C02 compound treatment 1077440.0 -36300.0 -0.18 960050.0 -155000.0 -0.92 973320.0 -94228.77118644 -0.539694572827461 -0.9463 -0.8739 356 Bio1_000372 CCNCCCNCCCCNCCCNCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C03 compound treatment 1046030.0 -67700.0 -0.33 1016040.0 -99000.0 -0.59 981680.0 -85868.77118644 -0.491812736186395 -0.815 -0.9754 357 Bio1_000373 Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(=O)(=O)C)cc3)n1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C04 compound treatment 1107800.0 -5980.0 -0.03 1052660.0 -62400.0 -0.37 1024420.0 -43128.77118644 -0.247019710105152 -0.3737 -0.8366 358 Bio1_000374 N[C@@H](CCCNC(=S)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C05 compound treatment 1041570.0 -72200.0 -0.35 1076520.0 -38500.0 -0.23 977120.0 -90428.77118644 -0.517930101626977 -0.635 -0.9517 359 Bio1_000375 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C06 compound treatment 1040030.0 -73700.0 -0.36 1082180.0 -32900.0 -0.2 904860.0 -162688.77118644 -0.93179870398146 -0.8589 -0.8437 360 Bio1_000376 Oc1ccc(cc1)c2cc(=O)c3c(O)cc(O)cc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C07 compound treatment 1071200.0 -42600.0 -0.21 1028910.0 -86100.0 -0.51 1107360.0 39811.22881356 0.228018511307537 -0.2842 -0.4752 3103683 Bio1_000377 COc1ccccc1.CS[C@H](C)[C@H](OC(=O)C)C(=O)N(C)CCN(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C08 compound treatment 1151430.0 37700.0 0.18 1196160.0 81100.0 0.48 979630.0 -87918.77118644 -0.503554095649814 0.0939 0.1302 361 Bio1_000378 CC(C)(c1ccc(OCC2CO2)cc1)c3ccc(OCC4CO4)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C09 compound treatment 1106560.0 -7220.0 -0.04 1122400.0 7340.0 0.04 992600.0 -74948.77118644 -0.429268518947107 -0.243 -0.5613 362 Bio1_000379 CCN(CC)CC(=O)Nc1c(C)cccc1C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C10 mock treatment 1123040.0 9260.0 0.05 1194340.0 79300.0 0.47 1016690.0 -50858.77118644 -0.291293226520875 0.1301 0.234 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C11 mock treatment 1070040.0 -43700.0 -0.21 1442300.0 327000.0 1.95 1063470.0 -4078.77118644002 -0.0233611310580635 0.9866 0.5039 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C12 mock treatment 1142280.0 28500.0 0.14 1155730.0 40700.0 0.24 1088260.0 20711.22881356 0.118623406062994 0.2885 0.9514 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C13 mock treatment 1242160.0 128000.0 0.63 1336970.0 222000.0 1.32 1001600.0 -65948.77118644 -0.377721087156485 0.9059 0.6003 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C14 mock treatment 1052410.0 -61400.0 -0.3 1131680.0 16600.0 0.1 1103370.0 35821.22881356 0.205165816547028 0.0024 0.0064 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C15 mock treatment 1075360.0 -38400.0 -0.19 1106670.0 -8390.0 -0.05 919890.0 -147658.77118644 -0.845714492891121 -0.6254 -0.7208 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C16 mock treatment 1138040.0 24300.0 0.12 1147730.0 32700.0 0.19 971920.0 -95628.77118644 -0.547713062217114 -0.1356 -0.2287 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C17 mock treatment 1046970.0 -66800.0 -0.33 1134020.0 19000.0 0.11 1042030.0 -25518.77118644 -0.146158568568168 -0.2077 -0.554 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C18 mock treatment 1034280.0 -79500.0 -0.39 1194560.0 79500.0 0.47 951290.0 -116258.77118644 -0.665871230866062 -0.3357 -0.3713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C19 mock treatment 1084280.0 -29500.0 -0.14 1219040.0 104000.0 0.62 1070050.0 2501.22881355998 0.0143257690733024 0.2821 0.4441 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C20 mock treatment 1060480.0 -53300.0 -0.26 1135590.0 20500.0 0.12 1022970.0 -44578.77118644 -0.255324574115863 -0.2273 -0.5909 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C21 mock treatment 1049310.0 -64500.0 -0.31 1068000.0 -47100.0 -0.28 910510.0 -157038.77118644 -0.899438371801792 -0.8627 -0.8686 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C22 mock treatment 1028800.0 -85000.0 -0.42 1147360.0 32300.0 0.19 1026560.0 -40988.77118644 -0.234762876323826 -0.2644 -0.5141 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C23 mock treatment 1045600.0 -68200.0 -0.33 1004530.0 -111000.0 -0.66 995700.0 -71848.77118644 -0.411513292441448 -0.8094 -0.959 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 C24 mock treatment 915440.0 -198000.0 -0.97 1151610.0 36600.0 0.22 915640.0 -151908.77118644 -0.870056335681137 -0.9363 -0.7091 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D01 compound treatment 57210.0 -1060000.0 -5.16 373770.0 -741000.0 -4.41 261690.0 -805858.77118644 -4.61555000451195 -8.1902 -0.9977 363 Bio1_000380 CC12C3CCC(O3)C2(C)C(=O)OC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D02 compound treatment 877820.0 -236000.0 -1.15 966930.0 -148000.0 -0.88 944330.0 -123218.77118644 -0.705734578117476 -1.5816 -0.9803 364 Bio1_000381 COc1cc(ccc1O)[C@H]2Oc3cc(ccc3O[C@@H]2CO)[C@@H]4Oc5cc(O)cc(O)c5C(=O)[C@H]4O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D03 compound treatment 991200.0 -123000.0 -0.6 955740.0 -159000.0 -0.95 930760.0 -136788.77118644 -0.783456650272892 -1.3451 -0.9836 365 Bio1_000382 CC(=O)OCOC(=O)CN(CC(=O)OCOC(=O)C)c1ccccc1OCCOc2ccccc2N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D04 compound treatment 1012020.0 -102000.0 -0.5 988410.0 -127000.0 -0.75 975600.0 -91948.77118644 -0.52663589010717 -1.0259 -0.9819 366 Bio1_000383 OC(=O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D05 compound treatment 509380.0 -604000.0 -2.95 397950.0 -717000.0 -4.26 347550.0 -719998.77118644 -4.12378750522942 -6.5478 -0.9881 2430 Bio1_000384 CC(C)C1NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D06 compound treatment 34430.0 -1080000.0 -5.27 50300.0 -1060000.0 -6.33 65540.0 -1002008.77118644 -5.73899764292645 -10.0137 -0.9972 368 Bio1_000385 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D07 compound treatment 43070.0 -1070000.0 -5.23 58280.0 -1060000.0 -6.28 41030.0 -1026518.77118644 -5.87937848216958 -10.0429 -0.9972 369 Bio1_000386 CCOc1ccc(cc1)c2nc3cc(ccc3[nH]2)c4nc5cc(ccc5[nH]4)N6CCN(C)CC6 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D08 compound treatment 1138670.0 24900.0 0.12 1243580.0 129000.0 0.76 1034630.0 -32918.77118644 -0.188542012484901 0.4026 0.5055 370 Bio1_000387 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D09 compound treatment 1015880.0 -97900.0 -0.48 1405280.0 290000.0 1.73 1023620.0 -43928.77118644 -0.251601704042096 0.575 0.3179 1000048 Bio1_000388 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D10 mock treatment 1059410.0 -54400.0 -0.27 1097700.0 -17400.0 -0.1 1061670.0 -5878.77118644002 -0.0336706174161879 -0.2324 -0.8098 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D11 mock treatment 1090340.0 -23400.0 -0.11 1030560.0 -84500.0 -0.5 973020.0 -94528.77118644 -0.541412820553816 -0.6688 -0.8948 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D12 mock treatment 1142570.0 28800.0 0.14 1333850.0 219000.0 1.3 1012370.0 -55178.77118644 -0.316035993780373 0.6499 0.4828 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D13 mock treatment 1043320.0 -70500.0 -0.34 1144960.0 29900.0 0.18 1011200.0 -56348.77118644 -0.322737159913154 -0.2824 -0.5601 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D14 mock treatment 1268730.0 155000.0 0.76 1171550.0 56500.0 0.34 1020880.0 -46668.77118644 -0.26729503327613 0.4767 0.5478 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D15 mock treatment 1053460.0 -60300.0 -0.29 1150660.0 35600.0 0.21 961250.0 -106298.77118644 -0.608825406351107 -0.3994 -0.5636 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D16 mock treatment 1152980.0 39200.0 0.19 1105460.0 -9600.0 -0.06 1017130.0 -50418.77118644 -0.288773129855555 -0.0891 -0.2537 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D17 mock treatment 1018240.0 -95500.0 -0.47 1338180.0 223000.0 1.33 1162450.0 94901.22881356 0.543546068790356 0.8103 0.5374 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D18 mock treatment 1061360.0 -52400.0 -0.26 1198090.0 83000.0 0.49 964700.0 -102848.77118644 -0.589065557498035 -0.2029 -0.2504 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D19 mock treatment 1173790.0 60000.0 0.29 1146270.0 31200.0 0.19 1148580.0 81031.22881356 0.464105748908586 0.5444 0.9394 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D20 mock treatment 1080400.0 -33400.0 -0.16 1098140.0 -16900.0 -0.1 1029240.0 -38308.77118644 -0.219413196635063 -0.2789 -0.9575 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D21 mock treatment 1092440.0 -21300.0 -0.1 1170050.0 55000.0 0.33 960880.0 -106668.77118644 -0.610944578546944 -0.2241 -0.3198 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D22 mock treatment 1038090.0 -75700.0 -0.37 1104260.0 -10800.0 -0.06 918400.0 -149148.77118644 -0.85424845659868 -0.7438 -0.7971 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D23 mock treatment 1058440.0 -55300.0 -0.27 1065440.0 -49600.0 -0.3 945830.0 -121718.77118644 -0.697143339485706 -0.729 -0.9068 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 D24 mock treatment 974990.0 -139000.0 -0.68 1051890.0 -63200.0 -0.38 971910.0 -95638.77118644 -0.547770337141326 -0.9246 -0.9741 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E01 compound treatment 1048960.0 -64800.0 -0.32 1100890.0 -14200.0 -0.08 1051530.0 -16018.77118644 -0.0917473905669555 -0.2845 -0.8359 372 Bio1_000389 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E02 compound treatment 949160.0 -165000.0 -0.8 799200.0 -316000.0 -1.88 826350.0 -241198.77118644 -1.38146413396832 -2.3464 -0.9513 373 Bio1_000390 CC(/C=C/c1cccc(Oc2ccc(F)cc2)c1)N(O)C(=O)N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E03 compound treatment 1142450.0 28700.0 0.14 1041890.0 -73200.0 -0.44 1058620.0 -8928.77118644002 -0.0511394693007876 -0.1999 -0.4345 2431 Bio1_000391 CCN(CC)CCNC(=O)c1ccc(N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E04 compound treatment 1187430.0 73700.0 0.36 1221600.0 107000.0 0.63 1183800.0 116251.22881356 0.665828031982554 0.958 0.9706 375 Bio1_000392 CCCCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E05 compound treatment 1091330.0 -22400.0 -0.11 1010310.0 -105000.0 -0.62 994320.0 -73228.77118644 -0.419417231982677 -0.6651 -0.8764 1000050 Bio1_000393 COc1ccc2nccc([C@@H](O)[C@@H]3CC4CC[C@@H]3CC4C=C)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E06 compound treatment 357770.0 -756000.0 -3.69 517000.0 -598000.0 -3.56 388320.0 -679228.77118644 -3.8902776392179 -6.4319 -0.9993 377 Bio1_000394 Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E07 compound treatment 1093770.0 -20000.0 -0.1 1236480.0 121000.0 0.72 1190280.0 122731.22881356 0.702942182871802 0.7663 0.7569 3103686 Bio1_000395 CC(C)[C@]1(O)[C@@H](OC(=O)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@@]1(C)C5(O)C[C@@]3(C)[C@@]6(O)CC[C@H](C)[C@@H](O)[C@]46O5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E08 compound treatment 1183060.0 69300.0 0.34 1152890.0 37800.0 0.22 1081510.0 13961.22881356 0.0799628322200279 0.3715 0.8968 379 Bio1_000396 O[C@H]1CCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E09 compound treatment 1310750.0 197000.0 0.96 1162400.0 47300.0 0.28 1056540.0 -11008.77118644 -0.0630526535368425 0.6818 0.6786 1000051 Bio1_000397 Cc1ccc(=O)n(c1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E10 mock treatment 1274340.0 161000.0 0.78 1182970.0 67900.0 0.4 994080.0 -73468.77118644 -0.42079183016376 0.4431 0.4533 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E11 mock treatment 1135860.0 22100.0 0.11 1244700.0 130000.0 0.77 1079900.0 12351.22881356 0.0707415694219277 0.5482 0.7014 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E12 mock treatment 1175570.0 61800.0 0.3 1283760.0 169000.0 1.0 1158430.0 90881.22881356 0.520521549257211 1.054 0.901 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E13 mock treatment 1148370.0 34600.0 0.17 1153760.0 38700.0 0.23 1003870.0 -63678.77118644 -0.364719679360405 0.0199 0.0429 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E14 mock treatment 1358300.0 245000.0 1.19 1372340.0 257000.0 1.53 1054150.0 -13398.77118644 -0.0767413604234633 1.5288 0.7869 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E15 mock treatment 1151640.0 37900.0 0.18 1124750.0 9690.0 0.06 1099460.0 31911.22881356 0.182771321180213 0.2456 0.9221 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E16 mock treatment 1138030.0 24300.0 0.12 1207390.0 92300.0 0.55 1103810.0 36261.22881356 0.207685913212347 0.5053 0.8438 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E17 mock treatment 1131840.0 18100.0 0.09 1283890.0 169000.0 1.0 981320.0 -86228.77118644 -0.49387463345802 0.3454 0.3078 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E18 mock treatment 1134560.0 20800.0 0.1 1231640.0 117000.0 0.69 1013230.0 -54318.77118644 -0.311110350298158 0.2793 0.3643 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E19 mock treatment 1277600.0 164000.0 0.8 1140490.0 25400.0 0.15 1077820.0 10271.22881356 0.0588283851858728 0.5834 0.7143 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E20 mock treatment 1076340.0 -37400.0 -0.18 1143330.0 28300.0 0.17 1021550.0 -45998.77118644 -0.263457613353939 -0.1607 -0.4436 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E21 mock treatment 1110480.0 -3300.0 -0.02 1109800.0 -5260.0 -0.03 1017350.0 -50198.77118644 -0.287513081522896 -0.1934 -0.6675 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E22 mock treatment 1097540.0 -16200.0 -0.08 1063730.0 -51300.0 -0.31 1001180.0 -66368.77118644 -0.38012663397338 -0.4415 -0.8939 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E23 mock treatment 1045730.0 -68000.0 -0.33 1198020.0 83000.0 0.49 1038910.0 -28638.77118644 -0.16402834492225 -0.0018 -0.003 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 E24 mock treatment 1026560.0 -87200.0 -0.43 1063390.0 -51700.0 -0.31 1046400.0 -21148.77118644 -0.12112942668761 -0.4934 -0.9151 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F01 compound treatment 980800.0 -133000.0 -0.65 1001280.0 -114000.0 -0.68 985620.0 -81928.77118644 -0.469246416046945 -1.0367 -0.9884 381 Bio1_000398 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3CCCC(=O)O3)[C@@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F02 compound treatment 59440.0 -1050000.0 -5.15 715320.0 -400000.0 -2.38 754310.0 -313238.77118644 -1.79407268799014 -5.3823 -0.9046 382 Bio1_000399 NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F03 compound treatment 141460.0 -972000.0 -4.75 276610.0 -838000.0 -4.99 366340.0 -701208.77118644 -4.01616792263544 -7.9401 -0.996 383 Bio1_000400 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F04 compound treatment 1127380.0 13600.0 0.07 1111900.0 -3160.0 -0.02 989860.0 -77688.77118644 -0.44496184818114 -0.2294 -0.5094 384 Bio1_000401 O=c1[nH]c2ccccc2c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F05 compound treatment 1204100.0 90300.0 0.44 1128320.0 13300.0 0.08 960480.0 -107068.77118644 -0.613235575515416 -0.0537 -0.0707 907367 Bio1_000402 CC(C)CC(NC(=O)C)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F06 compound treatment 926130.0 -188000.0 -0.92 1029190.0 -85900.0 -0.51 819230.0 -248318.77118644 -1.42224388000712 -1.6453 -0.9308 386 Bio1_000403 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CC[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F07 compound treatment 1356040.0 242000.0 1.18 1270730.0 156000.0 0.93 983520.0 -84028.77118644 -0.481274150131423 0.94 0.5957 387 Bio1_000404 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F08 compound treatment 114460.0 -999000.0 -4.88 136500.0 -979000.0 -5.82 118180.0 -949368.77118644 -5.43750244187553 -9.3179 -0.9975 388 Bio1_000405 COc1cc(/C=C/C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F09 compound treatment 1035000.0 -78800.0 -0.38 1241000.0 126000.0 0.75 1152330.0 84781.22881356 0.485583845488012 0.4905 0.5046 389 Bio1_000406 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F10 mock treatment 1096640.0 -17100.0 -0.08 1113000.0 -2060.0 -0.01 1013830.0 -53718.77118644 -0.30767385484545 -0.233 -0.7303 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F11 mock treatment 1067540.0 -46200.0 -0.23 1163910.0 48900.0 0.29 1046400.0 -21148.77118644 -0.12112942668761 -0.0326 -0.0843 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F12 mock treatment 1149810.0 36000.0 0.18 1277880.0 163000.0 0.97 1200980.0 133431.22881356 0.76422635177843 1.1019 0.8843 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F13 mock treatment 1171740.0 58000.0 0.28 1165560.0 50500.0 0.3 1048640.0 -18908.77118644 -0.108299843664166 0.2744 0.6429 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F14 mock treatment 1193760.0 80000.0 0.39 1193040.0 78000.0 0.46 1270740.0 203191.22881356 1.16377622307996 1.1652 0.8879 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F15 mock treatment 1083110.0 -30700.0 -0.15 1169570.0 54500.0 0.32 1031270.0 -36278.77118644 -0.207786387020067 -0.0193 -0.0468 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F16 mock treatment 1135920.0 22100.0 0.11 1033760.0 -81300.0 -0.48 973800.0 -93748.77118644 -0.536945376465295 -0.5267 -0.7209 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F17 mock treatment 1113610.0 -169.0 0.0 1185280.0 70200.0 0.42 1027620.0 -39928.77118644 -0.228691734357375 0.1086 0.2281 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F18 mock treatment 1190270.0 76500.0 0.37 1188200.0 73100.0 0.43 1014760.0 -52788.77118644 -0.302347286893753 0.2923 0.4509 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F19 mock treatment 1168430.0 54700.0 0.27 1132920.0 17900.0 0.11 996260.0 -71288.77118644 -0.408305896685587 -0.0203 -0.0406 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F20 mock treatment 1148510.0 34700.0 0.17 1108730.0 -6330.0 -0.04 921860.0 -145688.77118644 -0.834431332821396 -0.4055 -0.4758 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F21 mock treatment 1092200.0 -21600.0 -0.11 1162770.0 47700.0 0.28 1027290.0 -40258.77118644 -0.230581806856364 -0.0302 -0.0793 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F22 mock treatment 1165930.0 52200.0 0.25 1141330.0 26300.0 0.16 1130810.0 63261.22881356 0.362328208584213 0.4465 0.9506 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F23 mock treatment 1081480.0 -32300.0 -0.16 1146750.0 31700.0 0.19 1060490.0 -7058.77118644002 -0.0404290584731806 -0.0056 -0.0227 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 F24 mock treatment 1028570.0 -85200.0 -0.42 1029570.0 -85500.0 -0.51 1072100.0 4551.22881355998 0.0260671285367219 -0.5188 -0.789 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G01 compound treatment 1131890.0 18100.0 0.09 1029720.0 -85300.0 -0.51 1005490.0 -62058.77118644 -0.355441141638093 -0.4471 -0.7144 390 Bio1_000407 COc1ccc(CCCOC(Cn2ccnc2)c3ccc(OC)cc3)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G02 compound treatment 1252170.0 138000.0 0.68 1028930.0 -86100.0 -0.51 1066880.0 -668.771186440019 -0.00383038190183892 0.0925 0.109 391 Bio1_000408 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G03 compound treatment 1094030.0 -19700.0 -0.1 1031260.0 -83800.0 -0.5 978030.0 -89518.77118644 -0.512718083523703 -0.6394 -0.8863 392 Bio1_000409 CCN(CC)CCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G04 compound treatment 1148880.0 35100.0 0.17 1163040.0 48000.0 0.29 1006720.0 -60828.77118644 -0.348396325960042 0.0626 0.1299 393 Bio1_000410 CC(C)NCC(O)c1ccc(N)c(C#N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G05 compound treatment 1188570.0 74800.0 0.37 1062120.0 -52900.0 -0.31 1099700.0 32151.22881356 0.184145919361296 0.1355 0.2625 3103746 Bio1_000411 C1CCC(CC1)/N=C(\NC2C3CC4CC(C3)CC2C4)/N5CCOCC5 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G06 compound treatment 1013880.0 -99900.0 -0.49 1071010.0 -44000.0 -0.26 939070.0 -128478.77118644 -0.735861188252884 -0.8579 -0.9314 395 Bio1_000412 C(Oc1ccccc1C2CC2)C3=NCCN3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G07 compound treatment 1179570.0 65800.0 0.32 1069490.0 -45600.0 -0.27 1116640.0 49091.22881356 0.281169640976089 0.1915 0.3786 396 Bio1_000413 CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G08 compound treatment 1102900.0 -10900.0 -0.05 1273150.0 158000.0 0.94 1067210.0 -338.771186440019 -0.00194030940284944 0.511 0.5426 397 Bio1_000414 CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G09 compound treatment 1131590.0 17800.0 0.09 1175200.0 60100.0 0.36 999450.0 -68098.77118644 -0.390035195862022 0.0315 0.0588 1000053 Bio1_000415 OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G10 mock treatment 1216190.0 102000.0 0.5 1175930.0 60900.0 0.36 1100400.0 32851.22881356 0.188155164056122 0.6065 0.9394 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G11 mock treatment 1150420.0 36600.0 0.18 1369510.0 254000.0 1.51 1153330.0 85781.22881356 0.491311337909192 1.2606 0.7874 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G12 mock treatment 1111940.0 -1840.0 -0.01 1351790.0 237000.0 1.41 1330900.0 263351.22881356 1.50834216713817 1.6784 0.8135 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G13 mock treatment 1517960.0 404000.0 1.97 1284860.0 170000.0 1.01 1063810.0 -3738.77118644002 -0.0214137836348622 1.7107 0.7713 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G14 mock treatment 1141800.0 28000.0 0.14 1175060.0 60000.0 0.36 1050360.0 -17188.77118644 -0.0984485566997364 0.2282 0.5783 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G15 mock treatment 1095360.0 -18400.0 -0.09 1115240.0 182.0 0.0 1026980.0 -40568.77118644 -0.23235732950693 -0.1855 -0.7444 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G16 mock treatment 1145320.0 31500.0 0.15 1116550.0 1490.0 0.01 1030090.0 -37458.77118644 -0.21454482807706 -0.0298 -0.1127 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G17 mock treatment 1109990.0 -3790.0 -0.02 1142450.0 27400.0 0.16 1055550.0 -11998.77118644 -0.068722871033811 0.0437 0.2457 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G18 mock treatment 1189060.0 75300.0 0.37 1081330.0 -33700.0 -0.2 1035360.0 -32188.77118644 -0.18436094301744 -0.0099 -0.0216 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G19 mock treatment 1413090.0 299000.0 1.46 1259760.0 145000.0 0.86 1188720.0 121171.22881356 0.694007294694761 1.7418 0.9501 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G20 mock treatment 1150570.0 36800.0 0.18 1322650.0 208000.0 1.23 1150400.0 82851.22881356 0.474529785115134 1.0905 0.817 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G21 mock treatment 1078410.0 -35400.0 -0.17 1202000.0 86900.0 0.52 1111460.0 43911.22881356 0.251501230234376 0.3439 0.5729 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G22 mock treatment 1042940.0 -70800.0 -0.35 1112110.0 -2950.0 -0.02 1010900.0 -56648.77118644 -0.324455407639508 -0.3973 -0.8368 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G23 mock treatment 1042910.0 -70900.0 -0.35 1075230.0 -39800.0 -0.24 991400.0 -76148.77118644 -0.436141509852523 -0.5885 -0.9724 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 G24 mock treatment 1129440.0 15700.0 0.08 1086370.0 -28700.0 -0.17 1101360.0 33811.22881356 0.193653556780455 0.0575 0.2136 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H01 compound treatment 554720.0 -559000.0 -2.73 698270.0 -417000.0 -2.48 723870.0 -343678.77118644 -1.96841755729087 -4.1444 -0.9913 399 Bio1_000416 Nc1nc2ccc(OC(F)(F)F)cc2s1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H02 compound treatment 733320.0 -380000.0 -1.86 855550.0 -260000.0 -1.54 943730.0 -123818.77118644 -0.709171073570185 -2.3736 -0.9427 3103749 Bio1_000417 CC(C)C[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC=O)C(C)C)C(=O)N[C@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](Cc5c[nH]c6ccccc56)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](Cc7c[nH]c8ccccc78)C(=O)NCCO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H03 compound treatment 1081140.0 -32600.0 -0.16 1107840.0 -7220.0 -0.04 996800.0 -70748.77118644 -0.40521305077815 -0.3508 -0.8017 401 Bio1_000418 COc1cccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H04 compound treatment 1021200.0 -92600.0 -0.45 953010.0 -162000.0 -0.96 897290.0 -170258.77118644 -0.975155821609795 -1.3805 -0.9563 1961 Bio1_000419 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H05 compound treatment 57640.0 -1060000.0 -5.16 56830.0 -1060000.0 -6.29 48070.0 -1019478.77118644 -5.83905693552447 -9.9835 -0.9968 403 Bio1_000420 COc1ccc(CC(N)C(=O)N[C@@H]2[C@@H](O)[C@@H](O[C@@H]2CO)n3cnc4c(ncnc34)N(C)C)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H06 compound treatment 1129560.0 15800.0 0.08 1125720.0 10700.0 0.06 996800.0 -70748.77118644 -0.40521305077815 -0.1528 -0.3662 404 Bio1_000421 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H07 compound treatment 1203360.0 89600.0 0.44 1166100.0 51000.0 0.3 1031360.0 -36188.77118644 -0.207270912702161 0.3083 0.5394 405 Bio1_000422 Cn1cnc(=N)c2nc[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H08 compound treatment 1315360.0 202000.0 0.98 1313440.0 198000.0 1.18 1069760.0 2211.22881355998 0.0126647962711601 1.257 0.8179 406 Bio1_000423 Cc1c(CC(=O)O)c2cc(C=O)ccc2n1C(=O)c3ccc(Cl)cc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H09 compound treatment 1233570.0 120000.0 0.59 1096210.0 -18800.0 -0.11 990830.0 -76718.77118644 -0.439406180532596 0.0195 0.0263 407 Bio1_000424 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H10 mock treatment 1148280.0 34500.0 0.17 1162040.0 47000.0 0.28 1062470.0 -5078.77118644002 -0.0290886234792437 0.2418 0.7382 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H11 mock treatment 1110240.0 -3540.0 -0.02 1146310.0 31300.0 0.19 1087040.0 19491.22881356 0.111635865309155 0.1618 0.7438 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H12 mock treatment 1114790.0 1010.0 0.0 1163900.0 48800.0 0.29 1263700.0 196151.22881356 1.12345467643485 0.8192 0.7059 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H13 mock treatment 1455710.0 342000.0 1.67 1218090.0 103000.0 0.61 1154500.0 86951.22881356 0.498012504041973 1.6058 0.869 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H14 mock treatment 1087360.0 -26400.0 -0.13 1108700.0 -6360.0 -0.04 1067220.0 -328.771186440019 -0.00188303447863764 -0.0974 -0.7244 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H15 mock treatment 1064590.0 -49200.0 -0.24 1470260.0 355000.0 2.11 1046420.0 -21128.77118644 -0.121014876839186 1.0109 0.4747 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H16 mock treatment 1141600.0 27800.0 0.14 1367450.0 252000.0 1.5 1321560.0 254011.22881356 1.45484738792434 1.785 0.8521 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H17 mock treatment 1153450.0 39700.0 0.19 1113380.0 -1680.0 -0.01 998190.0 -69358.77118644 -0.397251836312709 -0.1232 -0.2787 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H18 mock treatment 1053440.0 -60300.0 -0.29 1124320.0 9260.0 0.06 1011360.0 -56188.77118644 -0.321820761125765 -0.3242 -0.737 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H19 mock treatment 1038170.0 -75600.0 -0.37 1105660.0 -9400.0 -0.06 1000410.0 -67138.77118644 -0.384536803137689 -0.4676 -0.8721 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H20 mock treatment 1125030.0 11300.0 0.05 1110610.0 -4450.0 -0.03 1083900.0 16351.22881356 0.0936515391066486 0.0705 0.6311 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H21 mock treatment 1168340.0 54600.0 0.27 1096000.0 -19100.0 -0.11 991170.0 -76378.77118644 -0.437458833109394 -0.1641 -0.3128 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H22 mock treatment 1077040.0 -36700.0 -0.18 1131260.0 16200.0 0.1 1282460.0 214911.22881356 1.2309024342562 0.6627 0.5311 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H23 mock treatment 1082570.0 -31200.0 -0.15 1123280.0 8220.0 0.05 1168960.0 101411.22881356 0.580832044452239 0.2755 0.4573 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 H24 mock treatment 1077600.0 -36200.0 -0.18 1154740.0 39700.0 0.24 1150850.0 83301.22881356 0.477107156704665 0.3096 0.5521 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I01 compound treatment 982180.0 -132000.0 -0.64 996130.0 -119000.0 -0.71 1058900.0 -8648.77118644002 -0.0495357714228572 -0.8081 -0.8444 1000056 Bio1_000425 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I02 compound treatment 1063840.0 -49900.0 -0.24 996340.0 -119000.0 -0.71 1112030.0 44481.22881356 0.254765900914449 -0.4014 -0.5086 409 Bio1_000426 CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(=O)(O)O[C@H]4[C@H]3OC(=O)CCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I03 compound treatment 1113340.0 -439.0 0.0 1000010.0 -115000.0 -0.68 1014640.0 -52908.77118644 -0.303034585984294 -0.5712 -0.7634 410 Bio1_000427 CC(=N)NCc1cccc(CN)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I04 compound treatment 64990.0 -1050000.0 -5.12 228440.0 -887000.0 -5.27 212120.0 -855428.77118644 -4.89946180382985 -8.8311 -0.9995 411 Bio1_000428 [I+]1c2ccccc2-c3ccccc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I05 compound treatment 1096890.0 -16900.0 -0.08 996580.0 -118000.0 -0.7 1037150.0 -30398.77118644 -0.174108731583527 -0.5549 -0.7598 412 Bio1_000429 COc1cc(OC)c2cc(cnc2c1)c3ccncc3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I06 compound treatment 374300.0 -739000.0 -3.61 885190.0 -230000.0 -1.37 1006770.0 -60778.77118644 -0.348109951338983 -3.0761 -0.7931 413 Bio1_000430 CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I07 compound treatment 68030.0 -1050000.0 -5.11 57120.0 -1060000.0 -6.29 58470.0 -1009078.77118644 -5.7794910143442 -9.9188 -0.9964 414 Bio1_000431 CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I08 compound treatment 339910.0 -774000.0 -3.78 304390.0 -811000.0 -4.82 337650.0 -729898.77118644 -4.1804896801991 -7.3798 -0.995 415 Bio1_000432 FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I09 compound treatment 1144210.0 30400.0 0.15 1046850.0 -68200.0 -0.41 1032980.0 -34568.77118644 -0.197992374979849 -0.2626 -0.5527 305 Bio1_000433 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I10 mock treatment 1112830.0 -949.0 0.0 1048740.0 -66300.0 -0.39 1023920.0 -43628.77118644 -0.249883456315742 -0.3746 -0.8024 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I11 mock treatment 1095750.0 -18000.0 -0.09 1104560.0 -10500.0 -0.06 1070260.0 2711.22881355998 0.0155285424817503 -0.0779 -0.7145 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I12 mock treatment 1139730.0 26000.0 0.13 1229000.0 114000.0 0.68 1098650.0 31101.22881356 0.178132052319057 0.5672 0.7967 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I13 mock treatment 1144640.0 30900.0 0.15 1183170.0 68100.0 0.41 1262630.0 195081.22881356 1.11732625954419 0.966 0.8063 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I14 mock treatment 1345610.0 232000.0 1.13 1066750.0 -48300.0 -0.29 998660.0 -68888.77118644 -0.394559914874754 0.2603 0.2111 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I15 mock treatment 1183810.0 70000.0 0.34 1056960.0 -58100.0 -0.35 1046890.0 -20658.77118644 -0.118322955401232 -0.0702 -0.1403 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I16 mock treatment 1122050.0 8270.0 0.04 1065920.0 -49100.0 -0.29 1034890.0 -32658.77118644 -0.187052864455395 -0.2534 -0.7254 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I17 mock treatment 1086340.0 -27400.0 -0.13 1113160.0 -1900.0 -0.01 1105930.0 38381.22881356 0.219828197145249 0.043 0.1668 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I18 mock treatment 1154170.0 40400.0 0.2 1290720.0 176000.0 1.04 1110310.0 42761.22881356 0.244914613950019 0.8584 0.7869 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I19 mock treatment 1095760.0 -18000.0 -0.09 1111730.0 -3330.0 -0.02 987810.0 -79738.77118644 -0.45670320764456 -0.3259 -0.7001 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I20 mock treatment 1136910.0 23100.0 0.11 1088920.0 -26100.0 -0.16 1022530.0 -45018.77118644 -0.257844670781182 -0.1734 -0.5391 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I21 mock treatment 1099040.0 -14700.0 -0.07 1116970.0 1910.0 0.01 1102570.0 35021.22881356 0.200583822610084 0.0808 0.3786 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I22 mock treatment 1041460.0 -72300.0 -0.35 990780.0 -124000.0 -0.74 985250.0 -82298.77118644 -0.471365588242781 -0.9028 -0.9553 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I23 mock treatment 1060520.0 -53300.0 -0.26 1015280.0 -99800.0 -0.59 1143200.0 75651.22881356 0.433291839682636 -0.2426 -0.3113 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 I24 mock treatment 1051040.0 -62700.0 -0.31 1071800.0 -43300.0 -0.26 1083580.0 16031.22881356 0.091818741531871 -0.2725 -0.6637 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J01 compound treatment 388720.0 -725000.0 -3.54 356370.0 -759000.0 -4.51 378630.0 -688918.77118644 -3.94577704077913 -6.9281 -0.9951 416 Bio1_000434 COc1cc(cc(OC)c1OC)[C@H]2[C@@H]3C(COC3=O)[C@@H](O)c4cc5OCOc5cc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J02 compound treatment 266630.0 -847000.0 -4.14 352010.0 -763000.0 -4.54 424210.0 -643338.77118644 -3.68471793622174 -7.1368 -0.9964 1000057 Bio1_000435 CC[C@]1(CC[C@@H](O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@H](O3)[C@@H](C)[C@@H](OC)C(C)C(=O)=[OH])O2)[C@@H]4O[C@H](C[C@@H]4C)[C@H]5O[C@@](O)(CO)CC[C@@H]5C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J03 compound treatment 156390.0 -957000.0 -4.68 609670.0 -505000.0 -3.01 773450.0 -294098.77118644 -1.68444848304875 -5.4083 -0.9309 417 Bio1_000436 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J04 compound treatment 1552260.0 438000.0 2.14 1346100.0 231000.0 1.37 1471970.0 404421.22881356 2.31631952299406 3.3674 0.9785 418 Bio1_000437 Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J05 compound treatment 1242980.0 129000.0 0.63 1000640.0 -114000.0 -0.68 1082240.0 14691.22881356 0.0841439016874894 0.0202 0.0217 419 Bio1_000438 CC1=NN(C(=O)C1)c2ccccc2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J06 compound treatment 279950.0 -834000.0 -4.07 807430.0 -308000.0 -1.83 816960.0 -250588.77118644 -1.4352452878032 -4.2369 -0.9032 420 Bio1_000439 CCN1C(=O)C=CC1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J07 compound treatment 210170.0 -904000.0 -4.41 215200.0 -900000.0 -5.35 180450.0 -887098.77118644 -5.08085148880863 -8.5718 -0.9969 421 Bio1_000440 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@@H](O)CC2CC(=O)NC(=O)C2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J08 compound treatment 716880.0 -397000.0 -1.94 872480.0 -243000.0 -1.44 787800.0 -279748.77118644 -1.60225896680482 -2.8775 -0.9923 422 Bio1_000441 Oc1cccc2C(=O)C=CC(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J09 mock treatment 1175920.0 62100.0 0.3 1121400.0 6340.0 0.04 1076240.0 8691.22881355998 0.0497789471604081 0.2258 0.7285 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J10 mock treatment 1187360.0 73600.0 0.36 1084160.0 -30900.0 -0.18 1093320.0 25771.22881356 0.147604517714166 0.1867 0.4343 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J11 mock treatment 1277560.0 164000.0 0.8 1125690.0 10600.0 0.06 1097920.0 30371.22881356 0.173950982851595 0.5989 0.7292 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J12 mock treatment 1187140.0 73400.0 0.36 1168710.0 53700.0 0.32 1337500.0 269951.22881356 1.54614361711796 1.2838 0.793 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J13 mock treatment 1165490.0 51700.0 0.25 1351460.0 236000.0 1.41 1458600.0 391051.22881356 2.23974294932288 2.2506 0.8472 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J14 mock treatment 1383200.0 269000.0 1.32 1180320.0 65300.0 0.39 1116800.0 49251.22881356 0.282086039763478 1.1469 0.8186 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J15 mock treatment 1237220.0 123000.0 0.6 1073390.0 -41700.0 -0.25 1060880.0 -6668.77118644002 -0.0381953364289203 0.1831 0.2803 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J16 mock treatment 1191770.0 78000.0 0.38 1100900.0 -14200.0 -0.08 1082270.0 14721.22881356 0.0843157264601249 0.2201 0.5512 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J17 mock treatment 1180550.0 66800.0 0.33 1145440.0 30400.0 0.18 1094280.0 26731.22881356 0.153102910438499 0.3811 0.9453 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J18 mock treatment 1188980.0 75200.0 0.37 1154740.0 39700.0 0.24 1200760.0 133211.22881356 0.762966303445771 0.7889 0.8974 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J19 mock treatment 1140030.0 26300.0 0.13 1141600.0 26500.0 0.16 1069460.0 1911.22881355998 0.0109465485448061 0.1715 0.842 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J20 mock treatment 1156070.0 42300.0 0.21 1118560.0 3500.0 0.02 1079750.0 12201.22881356 0.0698824455587507 0.1717 0.7834 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J21 mock treatment 1124920.0 11100.0 0.05 1118530.0 3470.0 0.02 1062180.0 -5368.77118644002 -0.030749596281386 0.0256 0.3887 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J22 mock treatment 1179940.0 66200.0 0.32 1233550.0 118000.0 0.7 1277510.0 209961.22881356 1.20255134677135 1.2877 0.9 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J23 mock treatment 1108280.0 -5500.0 -0.03 1105440.0 -9620.0 -0.06 1211840.0 144291.22881356 0.826426919472448 0.4286 0.5171 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 J24 mock treatment 1096520.0 -17300.0 -0.08 1063870.0 -51200.0 -0.3 1103040.0 35491.22881356 0.203275744048038 -0.1071 -0.285 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K01 compound treatment 1228110.0 114000.0 0.56 1026090.0 -89000.0 -0.53 1063520.0 -4028.77118644002 -0.0230747564370045 0.0037 0.0049 423 Bio1_000442 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K02 compound treatment 814730.0 -299000.0 -1.46 857160.0 -258000.0 -1.53 874080.0 -193468.77118644 -1.10809092070539 -2.3688 -0.9909 424 Bio1_000443 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K03 compound treatment 1165280.0 51500.0 0.25 993000.0 -122000.0 -0.73 1071370.0 3821.22881355998 0.0218860590692603 -0.2611 -0.3398 469 Bio1_000444 CCCC(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K04 compound treatment 429020.0 -685000.0 -3.35 507560.0 -607000.0 -3.61 599600.0 -467948.77118644 -2.68017304047094 -5.5647 -0.9926 425 Bio1_000445 Oc1ccc(cc1)c2coc3cc(O)cc(O)c3c2=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K05 compound treatment 1189510.0 75700.0 0.37 1039550.0 -75500.0 -0.45 1222880.0 155331.22881356 0.889658435802277 0.468 0.4403 1523 Bio1_000446 CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K06 compound treatment 327430.0 -786000.0 -3.84 1081480.0 -33600.0 -0.2 1140010.0 72461.22881356 0.415021138859071 -2.0938 -0.5411 426 Bio1_000447 NCCNS(=O)(=O)c1cccc2cnccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K07 compound treatment 18640.0 -1100000.0 -5.35 619040.0 -496000.0 -2.95 959280.0 -108268.77118644 -0.620108566420832 -5.1502 -0.8386 1049523 Bio1_000448 NCCCNC1CCCCC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K08 compound treatment 25450.0 -1090000.0 -5.32 75200.0 -1040000.0 -6.18 123010.0 -944538.77118644 -5.40983865348123 -9.7635 -0.9976 428 Bio1_000449 Clc1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K09 mock treatment 1122030.0 8250.0 0.04 1130240.0 15200.0 0.09 1067800.0 251.228813559981 0.00143891112564689 0.0762 0.7709 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K10 mock treatment 1120230.0 6450.0 0.03 1110370.0 -4690.0 -0.03 1082790.0 15241.22881356 0.0872940225191386 0.0525 0.5418 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K11 mock treatment 1199760.0 86000.0 0.42 1118200.0 3140.0 0.02 1491200.0 423651.22881356 2.42645920225336 1.6542 0.6717 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K12 mock treatment 1272340.0 159000.0 0.77 1267680.0 153000.0 0.91 1103790.0 36241.22881356 0.207571363363923 1.0911 0.9009 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K13 mock treatment 1290110.0 176000.0 0.86 1126800.0 11700.0 0.07 1073560.0 6011.22881355998 0.034429267471645 0.5576 0.6446 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K14 mock treatment 1156900.0 43100.0 0.21 1136530.0 21500.0 0.13 1129030.0 61481.22881356 0.352133272074513 0.3987 0.9276 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K15 mock treatment 1168440.0 54700.0 0.27 1065790.0 -49300.0 -0.29 1065060.0 -2488.77118644002 -0.0142544181083869 -0.0232 -0.0585 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K16 mock treatment 1161340.0 47600.0 0.23 1048180.0 -66900.0 -0.4 985380.0 -82168.77118644 -0.470621014228028 -0.3672 -0.5576 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K17 mock treatment 1097140.0 -16600.0 -0.08 1094330.0 -20700.0 -0.12 1117240.0 49691.22881356 0.284606136428798 0.0462 0.1441 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K18 mock treatment 1171560.0 57800.0 0.28 1243270.0 128000.0 0.76 1203970.0 136421.22881356 0.781351554117759 1.0543 0.935 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K19 mock treatment 1152800.0 39000.0 0.19 1084980.0 -30100.0 -0.18 1046280.0 -21268.77118644 -0.121816725778152 -0.0635 -0.2203 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K20 mock treatment 1021790.0 -92000.0 -0.45 1122580.0 7520.0 0.04 1240050.0 172501.22881356 0.987999480673942 0.3368 0.31 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K21 mock treatment 1166050.0 52300.0 0.26 1089000.0 -26100.0 -0.15 1137550.0 70001.22881356 0.400931507502968 0.2895 0.5789 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K22 mock treatment 1170770.0 57000.0 0.28 1048430.0 -66600.0 -0.4 1118900.0 51351.22881356 0.294113773847957 0.1018 0.1797 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K23 mock treatment 1010010.0 -104000.0 -0.51 1075710.0 -39300.0 -0.23 1189280.0 121731.22881356 0.697214690450622 -0.0253 -0.0283 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 K24 mock treatment 1024680.0 -89100.0 -0.44 1062900.0 -52200.0 -0.31 1200680.0 133131.22881356 0.762508104052076 0.0098 0.0106 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L01 compound treatment 996730.0 -117000.0 -0.57 912840.0 -202000.0 -1.2 891970.0 -175578.77118644 -1.00562608129047 -1.605 -0.9619 429 Bio1_000450 NCCc1c[nH]c2ccc(O)cc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L02 compound treatment 428990.0 -685000.0 -3.35 416480.0 -699000.0 -4.15 466170.0 -601378.77118644 -3.44439235422902 -6.3187 -0.9952 430 Bio1_000451 NC(=O)NO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L03 compound treatment 42740.0 -1070000.0 -5.23 44000.0 -1070000.0 -6.37 43560.0 -1023988.77118644 -5.86488792634399 -10.0845 -0.9968 431 Bio1_000452 C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L04 compound treatment 713080.0 -401000.0 -1.96 759790.0 -355000.0 -2.11 729480.0 -338068.77118644 -1.93628632480805 -3.4679 -0.9992 1000059 Bio1_000453 Cc1cn([C@H]2C[C@@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L05 compound treatment 79200.0 -1030000.0 -5.05 328730.0 -786000.0 -4.68 515620.0 -551928.77118644 -3.16116785400165 -7.4431 -0.9824 433 Bio1_000454 CN(C)c1ncnc2[nH]ccc12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L06 compound treatment 671740.0 -442000.0 -2.16 704320.0 -411000.0 -2.44 744970.0 -322578.77118644 -1.84756746720397 -3.7238 -0.9937 3000363 Bio1_000455 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L07 compound treatment 820740.0 -293000.0 -1.43 1026590.0 -88500.0 -0.53 1099230.0 31681.22881356 0.181453997923342 -1.0256 -0.6677 435 Bio1_000456 CC(C)Cn1c(=O)n(C)c(=O)c2nc[nH]c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L08 compound treatment 34400.0 -1080000.0 -5.27 41530.0 -1070000.0 -6.38 39220.0 -1028328.77118644 -5.88974524345192 -10.1309 -0.997 436 Bio1_000457 CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L09 mock treatment 1369730.0 256000.0 1.25 1008260.0 -107000.0 -0.64 1047910.0 -19638.77118644 -0.112480913131628 0.2904 0.2064 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L10 mock treatment 1082400.0 -31400.0 -0.15 1124170.0 9110.0 0.05 1295040.0 227491.22881356 1.30295428891464 0.695 0.5293 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L11 mock treatment 1124740.0 11000.0 0.05 1184000.0 68900.0 0.41 1404480.0 336931.22881356 1.92977105948861 1.3818 0.7001 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L12 mock treatment 1162240.0 48500.0 0.24 1071620.0 -43400.0 -0.26 1049850.0 -17698.77118644 -0.101369577834538 -0.071 -0.1945 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L13 mock treatment 1171520.0 57700.0 0.28 1251880.0 137000.0 0.81 1196640.0 129091.22881356 0.739369034670508 1.0595 0.9335 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L14 mock treatment 1227440.0 114000.0 0.56 1053160.0 -61900.0 -0.37 1031540.0 -36008.77118644 -0.206239964066348 -0.011 -0.0157 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L15 mock treatment 1305280.0 192000.0 0.94 1112960.0 -2100.0 -0.01 1060220.0 -7328.77118644002 -0.0419754814268993 0.5088 0.5432 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L16 mock treatment 1134450.0 20700.0 0.1 1025380.0 -89700.0 -0.53 1046430.0 -21118.77118644 -0.120957601914975 -0.3194 -0.5744 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L17 mock treatment 1067470.0 -46300.0 -0.23 1133120.0 18100.0 0.11 1117180.0 49631.22881356 0.284262486883527 0.0955 0.2521 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L18 mock treatment 1080860.0 -32900.0 -0.16 1071760.0 -43300.0 -0.26 1359900.0 292351.22881356 1.67443944735239 0.7252 0.4262 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L19 mock treatment 1137970.0 24200.0 0.12 1083840.0 -31200.0 -0.19 1215580.0 148031.22881356 0.847847741127662 0.4506 0.5144 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L20 mock treatment 1085350.0 -28400.0 -0.14 1017950.0 -97100.0 -0.58 1011280.0 -56268.77118644 -0.32227896051946 -0.5997 -0.8874 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L21 mock treatment 1096450.0 -17300.0 -0.08 1090530.0 -24500.0 -0.15 1144120.0 76571.22881356 0.438561132710122 0.1201 0.2556 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L22 mock treatment 1179770.0 66000.0 0.32 1047390.0 -67700.0 -0.4 1098080.0 30531.22881356 0.174867381638984 0.0548 0.1006 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L23 mock treatment 1098010.0 -15800.0 -0.08 1006830.0 -108000.0 -0.64 988440.0 -79108.77118644 -0.453094887419216 -0.6777 -0.8569 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 L24 mock treatment 962430.0 -151000.0 -0.74 1121080.0 6020.0 0.04 1279300.0 211751.22881356 1.21280355820527 0.294 0.2069 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M01 compound treatment 1295470.0 182000.0 0.89 1083850.0 -31200.0 -0.19 1051810.0 -15738.77118644 -0.090143692689025 0.3533 0.3877 437 Bio1_000458 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M02 compound treatment 1049640.0 -64100.0 -0.31 811490.0 -304000.0 -1.81 873250.0 -194298.77118644 -1.11284473941497 -1.8657 -0.8703 438 Bio1_000459 CCOC(=O)C1=C(C)NC(=S)NC1c2cccc(O)c2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M03 compound treatment 1115140.0 1360.0 0.01 927210.0 -188000.0 -1.12 1044770.0 -22778.77118644 -0.130465239334134 -0.7164 -0.637 439 Bio1_000460 CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(=O)C)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M04 compound treatment 41760.0 -1070000.0 -5.24 389020.0 -726000.0 -4.32 410680.0 -656868.77118644 -3.76221090868031 -7.6888 -0.9907 440 Bio1_000461 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M05 compound treatment 3590.0 -1110000.0 -5.42 18770.0 -1100000.0 -6.52 22100.0 -1045448.77118644 -5.98779991370252 -10.3525 -0.9972 441 Bio1_000462 O=CCCCC=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M06 compound treatment 86660.0 -1030000.0 -5.02 522440.0 -593000.0 -3.52 593710.0 -473838.77118644 -2.71390797083169 -6.4988 -0.9691 442 Bio1_000463 CCCCCCCCCCCCCCCCCCc1ccc(cc1)C(=O)/C=C/C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M07 compound treatment 1114360.0 581.0 0.0 1072560.0 -42500.0 -0.25 1342640.0 275091.22881356 1.57558292816282 0.7654 0.4797 1000061 Bio1_000464 [N-]=[N+]=[N-] 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M08 compound treatment 597290.0 -516000.0 -2.52 747900.0 -367000.0 -2.18 756130.0 -311418.77118644 -1.7836486517836 -3.7473 -0.9904 444 Bio1_000465 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OCCSc2ccccc2)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M09 mock treatment 1161760.0 48000.0 0.23 1100480.0 -14600.0 -0.09 1265710.0 198161.22881356 1.13496693620143 0.7406 0.6372 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M10 mock treatment 1161640.0 47900.0 0.23 1067780.0 -47300.0 -0.28 1011360.0 -56188.77118644 -0.321820761125765 -0.2131 -0.4375 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M11 mock treatment 1411580.0 298000.0 1.46 1113250.0 -1810.0 -0.01 1164320.0 96771.22881356 0.554256479617963 1.1538 0.741 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M12 mock treatment 1150730.0 37000.0 0.18 1237040.0 122000.0 0.73 1248420.0 180871.22881356 1.03593859223922 1.1211 0.8776 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M13 mock treatment 1219200.0 105000.0 0.52 1161850.0 46800.0 0.28 1100880.0 33331.22881356 0.190904360418289 0.5682 0.9228 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M14 mock treatment 1124380.0 10600.0 0.05 1127880.0 12800.0 0.08 1100160.0 32611.22881356 0.186780565875039 0.1818 0.8727 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M15 mock treatment 1122850.0 9070.0 0.04 1051640.0 -63400.0 -0.38 1036160.0 -31388.77118644 -0.179778949080496 -0.2959 -0.7044 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M16 mock treatment 1161650.0 47900.0 0.23 1220700.0 106000.0 0.63 1352100.0 284551.22881356 1.62976500646719 1.4387 0.8164 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M17 mock treatment 1175590.0 61800.0 0.3 1079620.0 -35400.0 -0.21 1125140.0 57591.22881356 0.329853326556121 0.2431 0.4918 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M18 mock treatment 1118410.0 4630.0 0.02 1045940.0 -69100.0 -0.41 1051860.0 -15688.77118644 -0.089857318067966 -0.2761 -0.6553 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M19 mock treatment 1164380.0 50600.0 0.25 978040.0 -137000.0 -0.81 1019910.0 -47638.77118644 -0.272850700924674 -0.4852 -0.5427 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M20 mock treatment 1091310.0 -22500.0 -0.11 1058310.0 -56700.0 -0.34 1104800.0 37251.22881356 0.213356130709316 -0.135 -0.3261 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M21 mock treatment 1155290.0 41500.0 0.2 1031730.0 -83300.0 -0.5 1040370.0 -27178.77118644 -0.155666205987327 -0.2589 -0.4643 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M22 mock treatment 1112030.0 -1750.0 -0.01 1047310.0 -67700.0 -0.4 1078100.0 10551.22881356 0.0604320830638033 -0.2026 -0.4973 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M23 mock treatment 1056340.0 -57400.0 -0.28 996900.0 -118000.0 -0.7 964920.0 -102628.77118644 -0.587805509165375 -0.9071 -0.9467 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 M24 mock treatment 909620.0 -204000.0 -1.0 963740.0 -151000.0 -0.9 1143750.0 76201.22881356 0.436441960514286 -0.8434 -0.5971 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N01 compound treatment 1057220.0 -56600.0 -0.28 970730.0 -144000.0 -0.86 1177930.0 110381.22881356 0.632207651470226 -0.2901 -0.2634 445 Bio1_000466 NC(=O)c1cccc(N)c1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N02 compound treatment 1047280.0 -66500.0 -0.32 931010.0 -184000.0 -1.09 1271780.0 204231.22881356 1.16973281519799 -0.1441 -0.0882 3103817 Bio1_000467 [2H][3H].OC(S)C1(O)CS1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N03 compound treatment 489350.0 -624000.0 -3.05 583390.0 -532000.0 -3.16 746750.0 -320798.77118644 -1.83737253069427 -4.6476 -0.9759 446 Bio1_000468 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N04 compound treatment 738090.0 -376000.0 -1.84 800690.0 -314000.0 -1.87 921150.0 -146398.77118644 -0.838497852440434 -2.6232 -0.9536 2069332 Bio1_000469 CC(=O)/C(=N/O)/C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N05 compound treatment 44660.0 -1070000.0 -5.22 296800.0 -818000.0 -4.87 376000.0 -691548.77118644 -3.96084034584684 -8.1119 -0.9936 448 Bio1_000470 Clc1cccc(Cl)c1N=C2NCCN2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N06 compound treatment 21990.0 -1090000.0 -5.33 41390.0 -1070000.0 -6.38 38720.0 -1028828.77118644 -5.89260898966251 -10.168 -0.9973 449 Bio1_000471 CC1=CC(=O)c2ccccc2C1=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N07 compound treatment 857080.0 -257000.0 -1.25 889960.0 -225000.0 -1.34 975750.0 -91798.77118644 -0.525776766243994 -1.8005 -0.9436 450 Bio1_000472 COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N08 compound treatment 1164640.0 50900.0 0.25 1034740.0 -80300.0 -0.48 1184410.0 116861.22881356 0.669321802359474 0.2541 0.2959 451 Bio1_000473 Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N09 mock treatment 1158560.0 44800.0 0.22 1003760.0 -111000.0 -0.66 1130240.0 62691.22881356 0.359063537904141 -0.0485 -0.0618 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N10 mock treatment 1148650.0 34900.0 0.17 1046020.0 -69000.0 -0.41 1137600.0 70051.22881356 0.401217882124027 0.093 0.1553 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N11 mock treatment 1183010.0 69200.0 0.34 1095740.0 -19300.0 -0.11 1352320.0 284771.22881356 1.63102505479985 1.0706 0.6412 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N12 mock treatment 1177800.0 64000.0 0.31 1134300.0 19200.0 0.11 1395320.0 327771.22881356 1.8773072289106 1.3305 0.6978 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N13 mock treatment 1262830.0 149000.0 0.73 1242580.0 128000.0 0.76 1300680.0 233131.22881356 1.3352573461701 1.6292 0.9586 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N14 mock treatment 1181830.0 68100.0 0.33 1098450.0 -16600.0 -0.1 1104070.0 36521.22881356 0.209175061241854 0.2557 0.6313 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N15 mock treatment 1173220.0 59400.0 0.29 1130440.0 15400.0 0.09 1308740.0 241191.22881356 1.38142093508481 1.018 0.7197 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N16 mock treatment 1161560.0 47800.0 0.23 1067680.0 -47400.0 -0.28 1136670.0 69121.22881356 0.395891314172329 0.2007 0.3723 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N17 mock treatment 1120640.0 6860.0 0.03 1056720.0 -58300.0 -0.35 1081020.0 13471.22881356 0.0771563609336496 -0.1364 -0.3821 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N18 mock treatment 1137950.0 24200.0 0.12 1084260.0 -30800.0 -0.18 1187970.0 120421.22881356 0.689711675378875 0.3606 0.4986 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N19 mock treatment 1156910.0 43100.0 0.21 1046080.0 -69000.0 -0.41 1088990.0 21441.22881356 0.122804475530456 -0.0443 -0.0927 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N20 mock treatment 1054030.0 -59700.0 -0.29 1123720.0 8660.0 0.05 1160000.0 92451.22881356 0.529513712358464 0.1669 0.275 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N21 mock treatment 1059590.0 -54200.0 -0.26 1058210.0 -56800.0 -0.34 1080810.0 13261.22881356 0.0759535875252017 -0.3042 -0.6976 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N22 mock treatment 1100050.0 -13700.0 -0.07 1010920.0 -104000.0 -0.62 1054980.0 -12568.77118644 -0.0719875417138837 -0.4378 -0.6982 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N23 mock treatment 1172500.0 58700.0 0.29 980480.0 -135000.0 -0.8 1198620.0 131071.22881356 0.750709469664445 0.137 0.1208 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 N24 mock treatment 934030.0 -180000.0 -0.88 997060.0 -118000.0 -0.7 1033410.0 -34138.77118644 -0.195529553238741 -1.025 -0.8984 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O01 compound treatment 886660.0 -227000.0 -1.11 1020040.0 -95000.0 -0.57 982300.0 -85248.77118644 -0.488261690885263 -1.2488 -0.9336 452 Bio1_000474 CC(C)(C)CC(C)(C)c1ccc(OCCO)cc1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O02 compound treatment 975680.0 -138000.0 -0.67 967300.0 -148000.0 -0.88 1168160.0 100611.22881356 0.576250050515295 -0.5641 -0.4518 453 Bio1_000475 COc1cccc(c1N)c2cc(=O)c3ccccc3o2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O03 compound treatment 878610.0 -235000.0 -1.15 1089920.0 -25100.0 -0.15 1270150.0 202601.22881356 1.16039700255147 -0.0797 -0.0486 1000063 Bio1_000476 CCCCCCCCCCCC(=O)O[C@@H]1[C@@H](O)CO[C@@H]1C2(CO)OCCO2 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O04 compound treatment 849990.0 -264000.0 -1.29 827780.0 -287000.0 -1.71 1024170.0 -43378.77118644 -0.248451583210447 -1.8738 -0.8698 455 Bio1_000477 Cc1ccc(cc1)C(=O)Cn2c3CCCCc3sc2=N 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O05 compound treatment 1101290.0 -12500.0 -0.06 1088020.0 -27000.0 -0.16 1104930.0 37381.22881356 0.214100704724069 -0.0044 -0.0162 456 Bio1_000478 CCNCCCNCCCNCCCNCC 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O06 compound treatment 782640.0 -331000.0 -1.62 1041010.0 -74000.0 -0.44 1090290.0 22741.22881356 0.13025021567799 -1.1131 -0.6619 457 Bio1_000479 Oc1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O07 compound treatment 1196320.0 82500.0 0.4 1240930.0 126000.0 0.75 1381820.0 314271.22881356 1.79998608122466 1.7042 0.8561 398 Bio1_000480 OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O08 compound treatment 111650.0 -1000000.0 -4.9 75760.0 -1040000.0 -6.18 77460.0 -990088.77118644 -5.67072593326598 -9.669 -0.9956 459 Bio1_000481 NCCCNCCCCN(CCCN)N(O)N=O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O09 mock treatment 1232530.0 119000.0 0.58 1071260.0 -43800.0 -0.26 1248690.0 181141.22881356 1.03748501519294 0.7836 0.6439 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O10 mock treatment 1113640.0 -139.0 0.0 1075750.0 -39300.0 -0.23 1386340.0 318791.22881356 1.8258743469684 0.9188 0.4991 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O11 mock treatment 1194840.0 81100.0 0.4 1082190.0 -32900.0 -0.2 1294310.0 226761.22881356 1.29877321944718 0.8657 0.631 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O12 mock treatment 1137180.0 23400.0 0.11 1208060.0 93000.0 0.55 1187840.0 120291.22881356 0.688967101364122 0.7831 0.879 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O13 mock treatment 1160910.0 47100.0 0.23 1041780.0 -73300.0 -0.44 997440.0 -70108.77118644 -0.401547455628594 -0.3505 -0.5513 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O14 mock treatment 1124580.0 10800.0 0.05 1115040.0 -18.3 0.0 1113360.0 45811.22881356 0.262383465834618 0.1819 0.6796 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O15 mock treatment 1049690.0 -64100.0 -0.31 1121530.0 6470.0 0.04 1061960.0 -5588.77118644002 -0.0320096446140457 -0.177 -0.5583 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O16 mock treatment 1114790.0 1010.0 0.0 1255120.0 140000.0 0.83 1297970.0 230421.22881356 1.3197358417087 1.2457 0.7982 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O17 mock treatment 1117400.0 3620.0 0.02 1038270.0 -76800.0 -0.46 1071100.0 3551.22881355998 0.0203396361155417 -0.2417 -0.5283 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O18 mock treatment 1071430.0 -42300.0 -0.21 1063890.0 -51200.0 -0.3 1147970.0 80421.22881356 0.460611978531666 -0.0292 -0.0495 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O19 mock treatment 1181250.0 67500.0 0.33 1055640.0 -59400.0 -0.35 1040800.0 -26748.77118644 -0.153203384246219 -0.1021 -0.2015 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O20 mock treatment 982880.0 -131000.0 -0.64 1056740.0 -58300.0 -0.35 1097080.0 29531.22881356 0.169139889217804 -0.4718 -0.6317 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O21 mock treatment 1108760.0 -5020.0 -0.02 1116420.0 1360.0 0.01 1046950.0 -20598.77118644 -0.117979305855961 -0.0776 -0.6425 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O22 mock treatment 1071330.0 -42400.0 -0.21 1076480.0 -38600.0 -0.23 1132280.0 64731.22881356 0.370747622443348 -0.0381 -0.079 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O23 mock treatment 1188000.0 74200.0 0.36 1045280.0 -69800.0 -0.41 1247940.0 180391.22881356 1.03318939587705 0.5663 0.4836 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 O24 mock treatment 970500.0 -143000.0 -0.7 957840.0 -157000.0 -0.93 879520.0 -188028.77118644 -1.07693336193417 -1.5657 -0.9855 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P01 compound treatment 710790.0 -403000.0 -1.97 871240.0 -244000.0 -1.45 740280.0 -327268.77118644 -1.8744294066593 -3.0561 -0.9919 460 Bio1_000482 CCC1NC(=O)C([C@H](O)[C@H](C)C/C=C/C)N(C)C(=O)C(C(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)C(CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P02 compound treatment 31520.0 -1080000.0 -5.29 461700.0 -653000.0 -3.89 581120.0 -486428.77118644 -2.78601710041435 -6.9045 -0.9686 461 Bio1_000483 CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P03 compound treatment 904600.0 -209000.0 -1.02 894410.0 -221000.0 -1.31 1025020.0 -42528.77118644 -0.243583214652443 -1.4882 -0.8854 462 Bio1_000484 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)[C@@H](O)CC2(C)C1(O)C(=O)CO 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P04 compound treatment 1146880.0 33100.0 0.16 977130.0 -138000.0 -0.82 1089930.0 22381.22881356 0.128188318406365 -0.3062 -0.362 463 Bio1_000485 OC[C@H]1OC(O)C[C@@H](O)[C@@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P05 compound treatment 389660.0 -724000.0 -3.54 344290.0 -771000.0 -4.58 349230.0 -718318.77118644 -4.11416531796183 -7.0642 -0.9945 464 Bio1_000486 CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)O)C(=O)O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P06 compound treatment 1012340.0 -101000.0 -0.5 958520.0 -157000.0 -0.93 1039520.0 -28028.77118644 -0.16053457454533 -0.9163 -0.8589 465 Bio1_000487 NCCc1c[nH]cn1 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P07 compound treatment 1157200.0 43400.0 0.21 981960.0 -133000.0 -0.79 1209790.0 142241.22881356 0.814685560009028 0.1359 0.1176 3103824 Bio1_000488 CC1O[C@@H](OC2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)C(CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)C(O)[C@@H](O)[C@H]1O 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P08 compound treatment 322020.0 -792000.0 -3.87 427810.0 -687000.0 -4.09 460160.0 -607388.77118644 -3.47881458368031 -6.6014 -0.9978 467 Bio1_000489 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)C(OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P09 mock treatment 1059130.0 -54600.0 -0.27 1013800.0 -101000.0 -0.6 1213880.0 146331.22881356 0.838111004011655 -0.0179 -0.0168 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P10 mock treatment 1066740.0 -47000.0 -0.23 965240.0 -150000.0 -0.89 1090460.0 22911.22881356 0.131223889389591 -0.5713 -0.6147 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P11 mock treatment 1240330.0 127000.0 0.62 1056970.0 -58100.0 -0.35 1285890.0 218341.22881356 1.25054773326084 0.8795 0.612 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P12 mock treatment 1124750.0 11000.0 0.05 1125250.0 10200.0 0.06 1305890.0 238341.22881356 1.36509758168445 0.8541 0.6246 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P13 mock treatment 1192800.0 79000.0 0.39 1094080.0 -21000.0 -0.12 1200160.0 132611.22881356 0.759529807993062 0.5894 0.6845 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P14 mock treatment 1121810.0 8030.0 0.04 1170290.0 55200.0 0.33 1105520.0 37971.22881356 0.217479925252565 0.3378 0.8534 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P15 mock treatment 998920.0 -115000.0 -0.56 1063590.0 -51500.0 -0.31 1033950.0 -33598.77118644 -0.192436707331304 -0.6118 -0.9165 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P16 mock treatment 1117720.0 3940.0 0.02 1141600.0 26500.0 0.16 1282260.0 214711.22881356 1.22975693577196 0.8122 0.655 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P17 mock treatment 1109710.0 -4070.0 -0.02 1097480.0 -17600.0 -0.1 1137680.0 70131.22881356 0.401676081517722 0.1601 0.3852 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P18 mock treatment 1084800.0 -29000.0 -0.14 1200420.0 85400.0 0.51 1137930.0 70381.22881356 0.403107954623017 0.4441 0.6693 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P19 mock treatment 1194880.0 81100.0 0.4 1062640.0 -52400.0 -0.31 1109010.0 41461.22881356 0.237468873802484 0.1859 0.3336 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P20 mock treatment 1063780.0 -50000.0 -0.24 1127920.0 12900.0 0.08 1167040.0 99491.22881356 0.569835259003573 0.2321 0.3716 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P21 mock treatment 958430.0 -155000.0 -0.76 1036420.0 -78600.0 -0.47 1046190.0 -21358.77118644 -0.122332200096058 -0.7788 -0.8655 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P22 mock treatment 1044440.0 -69300.0 -0.34 1074260.0 -40800.0 -0.24 1147610.0 80061.22881356 0.458550081260041 -0.0709 -0.1145 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P23 mock treatment 1120760.0 6980.0 0.03 920730.0 -194000.0 -1.16 1071200.0 3651.22881355998 0.0209123853576597 -0.6354 -0.5495 1054.0024 CellTiterGlo(1054.0024) KRasSyntheticLethal 1054.0024.685 P24 mock treatment 884000.0 -230000.0 -1.12 877650.0 -237000.0 -1.41 966880.0 -100668.77118644 -0.576579624019862 -1.7961 -0.9485