ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A01 compound treatment 1.09363E7 -7930000.0 -0.53 -0.5327 -1.0 3131442 CMLD2_000001 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A02 compound treatment 1.44636E7 -4400000.0 -0.3 -0.2958 -1.0 3131443 CMLD2_000002 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A03 compound treatment 3206240.0 -1.57E7 -1.05 -1.0518 -1.0 3010137 CMLD2_000003 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A04 compound treatment 1.04639E7 -8400000.0 -0.56 -0.5644 -1.0 3131444 CMLD2_000004 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A05 compound treatment 8061740.0 -1.08E7 -0.73 -0.7257 -1.0 3131445 CMLD2_000005 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A06 compound treatment 1.39347E7 -4930000.0 -0.33 -0.3313 -1.0 3010139 CMLD2_000006 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A07 compound treatment 1.92391E7 371000.0 0.02 0.0249 1.0 3131446 CMLD2_000007 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A08 compound treatment 2.42999E7 5430000.0 0.36 0.3648 1.0 3010141 CMLD2_000008 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A09 compound treatment 1.27591E7 -6110000.0 -0.41 -0.4103 -1.0 3010141 CMLD2_000009 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A10 compound treatment 2.39116E7 5040000.0 0.34 0.3387 1.0 3010142 CMLD2_000010 CC(C)[C@H](O)C1=CCCCC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A11 compound treatment 1.09934E7 -7870000.0 -0.53 -0.5288 -1.0 3131447 CMLD2_000011 O=C(OCc1ccccc1)C(C2CCCC(=O)C2)C(=O)OCc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A12 compound treatment 1.70992E7 -1770000.0 -0.12 -0.1188 -1.0 3010143 CMLD2_000012 COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A13 mock treatment 1.57735E7 -3090000.0 -0.21 -0.2078 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A14 mock treatment 1.73327E7 -1540000.0 -0.1 -0.1031 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A15 compound treatment 9557490.0 -9310000.0 -0.63 -0.6253 -1.0 3131448 CMLD2_000013 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A16 compound treatment 2.31618E7 4290000.0 0.29 0.2883 1.0 3131449 CMLD2_000014 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A17 compound treatment 2.307E7 4200000.0 0.28 0.2822 1.0 3010159 CMLD2_000015 COC(=O)[C@@H]1CCCN1C(=O)[C@@H](C)CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A18 mock treatment 1.36723E7 -5200000.0 -0.35 -0.3489 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A19 compound treatment 1.26702E7 -6200000.0 -0.42 -0.4162 -1.0 3131450 CMLD2_000016 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A20 compound treatment 1.7899E7 -969000.0 -0.07 -0.0651 -1.0 3010162 CMLD2_000017 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A21 compound treatment 5513100.0 -1.34E7 -0.9 -0.8969 -1.0 3131451 CMLD2_000018 COc1ccc(OC[C@H]2Cc3c(nc4CCN(CCOc5ccccc5)Cc4c3CO2)c6ccccc6)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A22 compound treatment 2.29929E7 4120000.0 0.28 0.277 1.0 3131452 CMLD2_000019 COC(=O)C1=C(C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A23 compound treatment 1.09892E7 -7880000.0 -0.53 -0.5291 -1.0 3010166 CMLD2_000020 COc1cccc(c1)[C@H]2N[C@@H](CC[C@@H]2C)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 A24 compound treatment 1.41673E7 -4700000.0 -0.32 -0.3157 -1.0 3010168 CMLD2_000021 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)C)c3ccccc3)C(=O)OC)c4ccccc4)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B01 compound treatment 3.12634E7 1.24E7 0.83 0.8324 1.0 3131453 CMLD2_000022 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B02 compound treatment 1.92659E7 398000.0 0.03 0.0267 1.0 3131569 CMLD2_000023 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B03 compound treatment 9676530.0 -9190000.0 -0.62 -0.6173 -1.0 3131570 CMLD2_000024 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B04 compound treatment 2.12761E7 2410000.0 0.16 0.1617 1.0 3010172 CMLD2_000025 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B05 compound treatment 3.18991E7 1.3E7 0.88 0.8751 1.0 3131571 CMLD2_000026 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B06 compound treatment 2.09332E7 2060000.0 0.14 0.1387 1.0 3010200 CMLD2_000027 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B07 compound treatment 2.99784E7 1.11E7 0.75 0.7461 1.0 3131572 CMLD2_000028 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B08 compound treatment 2.7454E7 8590000.0 0.58 0.5766 1.0 3010203 CMLD2_000029 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B09 compound treatment 1.68377E7 -2030000.0 -0.14 -0.1364 -1.0 3010205 CMLD2_000030 COC(=O)NC/C=C\c1nc(CC/C=C\C(=O)OC)co1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B10 compound treatment 5504590.0 -1.34E7 -0.9 -0.8974 -1.0 3131573 CMLD2_000031 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@H](O)c2c(=O)o1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B11 compound treatment 1.3705E7 -5160000.0 -0.35 -0.3467 -1.0 3010207 CMLD2_000032 CC1(C)OCC(CO1)C(O)C2=CCCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B12 compound treatment 1.79178E7 -950000.0 -0.06 -0.0638 -1.0 3131574 CMLD2_000033 COC(=O)[C@H](C)NC(=O)[C@@H](C)CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B13 mock treatment 1.93384E7 470000.0 0.03 0.0316 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B14 mock treatment 1.32878E7 -5580000.0 -0.37 -0.3748 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B15 compound treatment 2.11305E7 2260000.0 0.15 0.1519 1.0 3010209 CMLD2_000034 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)OC(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B16 compound treatment 3.10526E7 1.22E7 0.82 0.8182 1.0 2082484 CMLD2_000035 COC(=O)C(C1CCCC(=O)C1)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B17 compound treatment 2.0457E7 1590000.0 0.11 0.1067 1.0 3131575 CMLD2_000036 COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B18 mock treatment 8386880.0 -1.05E7 -0.7 -0.7039 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B19 compound treatment 2.49536E7 6090000.0 0.41 0.4087 1.0 3010212 CMLD2_000037 CO[C@@H]1[C@H](O)CO[C@H]1/C=C/c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B20 compound treatment 1.77644E7 -1100000.0 -0.07 -0.0741 -1.0 3131576 CMLD2_000038 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B21 compound treatment 2.03784E7 1510000.0 0.1 0.1014 1.0 3010215 CMLD2_000039 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B22 compound treatment 3.65634E7 1.77E7 1.19 1.1883 1.0 3131577 CMLD2_000040 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B23 compound treatment 1.5442E7 -3430000.0 -0.23 -0.2301 -1.0 3010186 CMLD2_000041 COc1ccc(cc1)c2ccccc2[C@@H]3N[C@@H](CC[C@H]3C)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 B24 compound treatment 1.20275E7 -6840000.0 -0.46 -0.4594 -1.0 3131578 CMLD2_000042 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCOC4=O)C(=O)CC)c5ccccc5)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C01 compound treatment 1.74685E7 -1400000.0 -0.09 -0.094 -1.0 3131579 CMLD2_000043 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6cccc7ccccc67 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C02 compound treatment 1.07193E7 -8150000.0 -0.55 -0.5472 -1.0 3010248 CMLD2_000044 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C03 compound treatment 2.09663E7 2100000.0 0.14 0.1409 1.0 3131580 CMLD2_000045 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C04 compound treatment 2.81775E7 9310000.0 0.63 0.6252 1.0 3131581 CMLD2_000046 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3ccc4OCOc4c3)O1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C05 compound treatment 1.34207E7 -5450000.0 -0.37 -0.3658 -1.0 3131582 CMLD2_000047 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C06 compound treatment 2.57257E7 6860000.0 0.46 0.4605 1.0 3010252 CMLD2_000048 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C07 compound treatment 1.39392E7 -4930000.0 -0.33 -0.331 -1.0 3131583 CMLD2_000049 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C08 compound treatment 7113810.0 -1.18E7 -0.79 -0.7894 -1.0 3010254 CMLD2_000050 Cc1cc2N(CC(O)CN3CCCc4nc(C)c(C)cc34)CCCc2nc1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C09 compound treatment 7007330.0 -1.19E7 -0.8 -0.7965 -1.0 3131584 CMLD2_000051 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C10 compound treatment 1.66687E7 -2200000.0 -0.15 -0.1477 -1.0 3010257 CMLD2_000052 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@@H](O)c2c(=O)o1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C11 mock treatment 1.7974E7 -894000.0 -0.06 -0.0601 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C12 mock treatment 1.0994E7 -7870000.0 -0.53 -0.5288 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C13 compound treatment 1.96762E7 808000.0 0.05 0.0543 1.0 3010259 CMLD2_000053 OC(CCOCc1ccccc1)C2=CCCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C14 compound treatment 1.16956E7 -7170000.0 -0.48 -0.4817 -1.0 1304363 CMLD2_000054 C1Cc2c([nH]c3ccccc23)C(N1)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C15 mock treatment 1.47564E7 -4110000.0 -0.28 -0.2761 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C16 mock treatment 1.99898E7 1120000.0 0.08 0.0753 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C17 compound treatment 1.29082E7 -5960000.0 -0.4 -0.4003 -1.0 3010233 CMLD2_000055 COc1ccc(cc1)c2cnnc(CCCn3ccnc3c4ccccc4)n2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C18 compound treatment 2.42244E7 5360000.0 0.36 0.3597 1.0 3131585 CMLD2_000056 Cc1ccc(O[C@H]2C=C[C@@H](CC=C)O[C@@H]2COC(=O)NCc3cccc4ccccc34)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C19 compound treatment 1.67097E7 -2160000.0 -0.14 -0.145 -1.0 3131586 CMLD2_000057 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2ccc(cc2)C(=O)OC)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C20 compound treatment 1.98119E7 944000.0 0.06 0.0634 1.0 3010236 CMLD2_000058 C[C@H]1CC[C@@H]2N(CC(CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C21 compound treatment 1.90145E7 146000.0 0.01 0.0098 1.0 3131587 CMLD2_000059 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2CC1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C22 compound treatment 6643660.0 -1.22E7 -0.82 -0.8209 -1.0 3131703 CMLD2_000060 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C23 compound treatment 7859760.0 -1.1E7 -0.74 -0.7393 -1.0 3010240 CMLD2_000061 OC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 C24 compound treatment 1.7846E7 -1020000.0 -0.07 -0.0687 -1.0 3131704 CMLD2_000062 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C4=O)c5ccccc5)C(=O)OC)c6ccccc6)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D01 compound treatment 2.33733E7 4510000.0 0.3 0.3025 1.0 3010292 CMLD2_000063 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D02 compound treatment 3.6938E7 1.81E7 1.21 1.2135 1.0 3131705 CMLD2_000064 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D03 compound treatment 6469600.0 -1.24E7 -0.83 -0.8326 -1.0 3131706 CMLD2_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D04 compound treatment 2.46317E7 5760000.0 0.39 0.387 1.0 3010296 CMLD2_000066 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D05 compound treatment 1664350.0 -1.72E7 -1.16 -1.1553 -1.0 3010274 CMLD2_000067 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D06 compound treatment 2.07038E7 1840000.0 0.12 0.1233 1.0 3131707 CMLD2_000068 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D07 compound treatment 2.15888E7 2720000.0 0.18 0.1827 1.0 3131708 CMLD2_000069 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D08 compound treatment 1.16286E7 -7240000.0 -0.49 -0.4862 -1.0 3010278 CMLD2_000070 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D09 compound treatment 3.78813E7 1.9E7 1.28 1.2768 1.0 3010279 CMLD2_000071 CN1CCN(CC(O)CN2CCCc3nc(C)c(C)cc23)CC1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D10 compound treatment 1.56971E7 -3170000.0 -0.21 -0.213 -1.0 3131709 CMLD2_000072 C[C@@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D11 mock treatment 4.89275E7 3.01E7 2.02 2.0186 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D12 mock treatment 1.5975E7 -2890000.0 -0.19 -0.1943 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D13 compound treatment 1.23754E7 -6490000.0 -0.44 -0.436 -1.0 3010281 CMLD2_000073 Brc1ccc(cc1)C(=O)OC(CCc2ccccc2)C3=CCCCC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D14 compound treatment 7173550.0 -1.17E7 -0.79 -0.7854 -1.0 3131710 CMLD2_000074 CCOC(=O)CC(C1CCCCC1=O)C(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D15 mock treatment 1.90057E7 137000.0 0.01 0.0092 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D16 mock treatment 1.75436E7 -1320000.0 -0.09 -0.089 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D17 compound treatment 9596540.0 -9270000.0 -0.62 -0.6226 -1.0 3131711 CMLD2_000075 COC(=O)C/C=C/[C@H](C)[C@H](CO)NS(=O)(=O)c1ccc(C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D18 compound treatment 8.50351E7 6.62E7 4.44 4.4435 1.0 3010283 CMLD2_000076 CCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D19 compound treatment 2.72611E7 8390000.0 0.56 0.5636 1.0 3131712 CMLD2_000077 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D20 compound treatment 1.43981E7 -4470000.0 -0.3 -0.3002 -1.0 3010285 CMLD2_000078 COC(=O)[C@@H]1CC[C@@H](C)[C@@H](N1)c2ccc(Br)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D21 compound treatment 1.09978E7 -7870000.0 -0.53 -0.5285 -1.0 3131713 CMLD2_000079 C[C@@H]1Cc2c(CO1)cnc3CCN(C)Cc32 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D22 compound treatment 1.53165E7 -3550000.0 -0.24 -0.2385 -1.0 3131714 CMLD2_000080 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D23 compound treatment 1.37004E7 -5170000.0 -0.35 -0.3471 -1.0 3010288 CMLD2_000081 COc1cc(cc(OC)c1OC)[C@@H]2N[C@@H](Cc3c2[nH]c4ccccc34)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 D24 compound treatment 1.72432E7 -1630000.0 -0.11 -0.1091 -1.0 3131715 CMLD2_000082 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E01 mock treatment 1.26113E7 -6260000.0 -0.42 -0.4202 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E02 mock treatment 1.58881E7 -2980000.0 -0.2 -0.2001 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E03 compound treatment 1.75283E7 -1340000.0 -0.09 -0.09 -1.0 3010304 CMLD2_000083 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E04 compound treatment 1.69432E7 -1930000.0 -0.13 -0.1293 -1.0 3131716 CMLD2_000084 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E05 compound treatment 5401230.0 -1.35E7 -0.9 -0.9044 -1.0 3131717 CMLD2_000085 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCCc3ccc(F)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E06 compound treatment 7881790.0 -1.1E7 -0.74 -0.7378 -1.0 3010306 CMLD2_000086 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E07 compound treatment 5785980.0 -1.31E7 -0.88 -0.8785 -1.0 3131718 CMLD2_000087 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E08 compound treatment 1.3832E7 -5040000.0 -0.34 -0.3382 -1.0 3131719 CMLD2_000088 Brc1ccc(cc1)c2ccc3N(CCCc3n2)C(=O)NCCCN4=CC=NC4c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E09 mock treatment 2.86885E7 9820000.0 0.66 0.6595 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E10 mock treatment 1.96784E7 810000.0 0.05 0.0544 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E11 compound treatment 1.86416E7 -227000.0 -0.02 -0.0152 -1.0 3010320 CMLD2_000089 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)NCc3cccc4ccccc34)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E12 compound treatment 3.08555E7 1.2E7 0.81 0.805 1.0 3131720 CMLD2_000090 CC(C)C(=O)N[C@H]1CCCN1C(=O)/C=C/c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E13 compound treatment 1.76453E7 -1220000.0 -0.08 -0.0821 -1.0 3010323 CMLD2_000091 OC(COCc1ccccc1)C2=CCCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E14 compound treatment 1.40283E7 -4840000.0 -0.33 -0.325 -1.0 3131721 CMLD2_000092 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3ccccc3O[C@]2([C@@H]1c4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E15 compound treatment 1.35598E7 -5310000.0 -0.36 -0.3565 -1.0 3010326 CMLD2_000093 COc1cc(O)c(C(=O)/C=C/c2ccc3OCOc3c2)c(OC)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E16 mock treatment 8671540.0 -1.02E7 -0.68 -0.6848 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E17 mock treatment 1.6591E7 -2280000.0 -0.15 -0.1529 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E18 mock treatment 2.62211E7 7350000.0 0.49 0.4938 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E19 compound treatment 4.06595E7 2.18E7 1.46 1.4634 1.0 3131722 CMLD2_000094 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E20 compound treatment 1.48677E7 -4000000.0 -0.27 -0.2687 -1.0 3131840 CMLD2_000095 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)C(F)(F)F)c2ccc(Br)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E21 compound treatment 5385550.0 -1.35E7 -0.91 -0.9054 -1.0 3010332 CMLD2_000096 C1Cc2nc(c3ccccc3)c(cc2CN1)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E22 compound treatment 2.86286E7 9760000.0 0.66 0.6555 1.0 3131841 CMLD2_000097 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCOC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E23 compound treatment 7138800.0 -1.17E7 -0.79 -0.7877 -1.0 3010340 CMLD2_000098 C[C@H]1CC[C@H](N[C@@H]1c2cccc(CC=C)c2)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 E24 compound treatment 1.00744E7 -8790000.0 -0.59 -0.5906 -1.0 3131842 CMLD2_000099 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCCC4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F01 mock treatment 2.08054E7 1940000.0 0.13 0.1301 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F02 mock treatment 1.99009E7 1030000.0 0.07 0.0693 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F03 compound treatment 8005950.0 -1.09E7 -0.73 -0.7295 -1.0 3131843 CMLD2_000100 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F04 compound treatment 1.34888E7 -5380000.0 -0.36 -0.3613 -1.0 3010347 CMLD2_000101 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F05 compound treatment 1.25406E7 -6330000.0 -0.42 -0.4249 -1.0 3131844 CMLD2_000102 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F06 compound treatment 2.89631E7 1.01E7 0.68 0.6779 1.0 3131845 CMLD2_000103 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F07 compound treatment 2.23183E7 3450000.0 0.23 0.2317 1.0 3011245 CMLD2_000104 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F08 compound treatment 3.61469E7 1.73E7 1.16 1.1604 1.0 3010203 CMLD2_000105 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F09 mock treatment 1.1471E7 -7400000.0 -0.5 -0.4968 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F10 mock treatment 1.88989E7 30600.0 0.0 0.0021 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F11 compound treatment 2.1579E7 2710000.0 0.18 0.182 1.0 3011246 CMLD2_000106 C[C@@]12CCC3C(CCc4cc(OCC5CO5)ccc34)C2CC[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F12 compound treatment 2.13515E7 2480000.0 0.17 0.1668 1.0 3011247 CMLD2_000107 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F13 compound treatment 2.27067E7 3840000.0 0.26 0.2578 1.0 3131846 CMLD2_000108 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(Br)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F14 compound treatment 2.66259E7 7760000.0 0.52 0.521 1.0 3011248 CMLD2_000109 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F15 compound treatment 1.51565E7 -3710000.0 -0.25 -0.2493 -1.0 1946418 CMLD2_000110 Fc1ccc(cc1)C(=O)/C=C/c2ccc3OCOc3c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F16 compound treatment 1.34599E7 -5410000.0 -0.36 -0.3632 -1.0 3011250 CMLD2_000111 OC(CCOC(c1ccccc1)(c2ccccc2)c3ccccc3)C4=CCCCC4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F17 mock treatment 2.139E7 2520000.0 0.17 0.1693 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F18 mock treatment 2.30544E7 4190000.0 0.28 0.2811 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F19 compound treatment 2.28662E7 4000000.0 0.27 0.2685 1.0 3131847 CMLD2_000112 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F20 compound treatment 7900100.0 -1.1E7 -0.74 -0.7366 -1.0 3131848 CMLD2_000113 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1)c2ccc(Br)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F21 compound treatment 2.4889E7 6020000.0 0.4 0.4043 1.0 3011251 CMLD2_000114 CN1CCc2nc(CO)c(CO)cc2C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F22 compound treatment 3.08777E7 1.2E7 0.81 0.8065 1.0 3131849 CMLD2_000115 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F23 compound treatment 1.95161E7 648000.0 0.04 0.0435 1.0 3011252 CMLD2_000116 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(c3)N4CCOCC4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6cccc(c6)N7CCOCC7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 F24 compound treatment 7865650.0 -1.1E7 -0.74 -0.7389 -1.0 3131850 CMLD2_000117 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C)C4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G01 compound treatment 2.08479E7 1980000.0 0.13 0.1329 1.0 3131851 CMLD2_000118 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCN3CCOCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G02 compound treatment 1.32986E7 -5570000.0 -0.37 -0.374 -1.0 3131852 CMLD2_000119 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G03 mock treatment 1.27464E7 -6120000.0 -0.41 -0.4111 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G04 mock treatment 2.18928E7 3020000.0 0.2 0.2031 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G05 compound treatment 2.08875E7 2020000.0 0.14 0.1356 1.0 3011253 CMLD2_000120 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G06 compound treatment 1.41102E7 -4760000.0 -0.32 -0.3195 -1.0 3131853 CMLD2_000121 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G07 compound treatment 2.13047E7 2440000.0 0.16 0.1636 1.0 3011254 CMLD2_000122 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)OC2CC(CCC3CC(=NO3)CC)OC4(CCCC(COC(=O)NCCC(C)C)O4)C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G08 compound treatment 1.21985E7 -6670000.0 -0.45 -0.4479 -1.0 3131854 CMLD2_000123 Cc1ccc(cc1)S(=O)(=O)NC(CCc2ccccc2)CC(=O)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G09 compound treatment 1.33162E7 -5550000.0 -0.37 -0.3729 -1.0 3131855 CMLD2_000124 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)N3CCCCC3)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G10 compound treatment 1.61039E7 -2760000.0 -0.19 -0.1856 -1.0 3011255 CMLD2_000125 O[C@H]1C=C(C=C)C2(OCCCO2)[C@H]3O[C@H]31 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G11 compound treatment 4722240.0 -1.41E7 -0.95 -0.95 -1.0 3011256 CMLD2_000126 OC(CCc1ccccc1)C2=CCCOC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G12 compound treatment 3.31704E7 1.43E7 0.96 0.9605 1.0 3131856 CMLD2_000127 C[C@H]1OC=C2[C@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](OC(=O)C)[C@H]7O[C@H]7C6=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G13 compound treatment 1.4468E7 -4400000.0 -0.3 -0.2955 -1.0 3011257 CMLD2_000128 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G14 compound treatment 6925760.0 -1.19E7 -0.8 -0.802 -1.0 3131857 CMLD2_000129 CC/C=C\CCC(OC(=O)c1ccc(Br)cc1)C2=CCCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G15 compound treatment 2.45746E7 5710000.0 0.38 0.3832 1.0 3011258 CMLD2_000130 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G16 mock treatment 2.27895E7 3920000.0 0.26 0.2633 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G17 compound treatment 2.07477E7 1880000.0 0.13 0.1262 1.0 3131858 CMLD2_000131 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G18 compound treatment 5.82503E7 3.94E7 2.64 2.6447 1.0 3131859 CMLD2_000132 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCCc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G19 mock treatment 7927010.0 -1.09E7 -0.73 -0.7348 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G20 mock treatment 1.60268E7 -2840000.0 -0.19 -0.1908 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G21 compound treatment 2.66135E7 7750000.0 0.52 0.5201 1.0 3011259 CMLD2_000133 CN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G22 compound treatment 2.76423E7 8770000.0 0.59 0.5892 1.0 3131977 CMLD2_000134 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G23 compound treatment 3.2088E7 1.32E7 0.89 0.8878 1.0 3011260 CMLD2_000135 C[C@H]1CC[C@@H]2N([C@@H]1c3cccc(CC=C)c3)C(=O)[C@@H]4CC[C@H](C)[C@H](N4C2=O)c5cccc(CC=C)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 G24 compound treatment 1.13651E7 -7500000.0 -0.5 -0.5039 -1.0 3131978 CMLD2_000136 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H01 compound treatment 8572800.0 -1.03E7 -0.69 -0.6914 -1.0 3131979 CMLD2_000137 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H02 compound treatment 1.72323E7 -1640000.0 -0.11 -0.1099 -1.0 3131980 CMLD2_000138 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H03 mock treatment 3.306E7 1.42E7 0.95 0.9531 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H04 mock treatment 2.58696E7 7000000.0 0.47 0.4702 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H05 compound treatment 5871340.0 -1.3E7 -0.87 -0.8728 -1.0 3011261 CMLD2_000139 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H06 compound treatment 8414860.0 -1.05E7 -0.7 -0.702 -1.0 3131981 CMLD2_000140 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H07 compound treatment 3.15093E7 1.26E7 0.85 0.8489 1.0 3422360 CMLD2_000141 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H08 compound treatment 1.03194E7 -8550000.0 -0.57 -0.5741 -1.0 3010278 CMLD2_000142 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H09 compound treatment 1.19371E7 -6930000.0 -0.47 -0.4655 -1.0 3011262 CMLD2_000143 CON(C)C(=O)c1nnc2c3ccccc3[nH]c2n1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H10 compound treatment 1.29221E8 1.1E8 7.41 7.4108 1.0 3011263 CMLD2_000144 C/C=C/C1=C(CO)C(=O)[C@@H]2O[C@@H]2C1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H11 compound treatment 1.41502E7 -4720000.0 -0.32 -0.3168 -1.0 3011264 CMLD2_000145 CCOC(=O)CC(CC(=O)C)C(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H12 compound treatment 2.50534E7 6190000.0 0.42 0.4154 1.0 3131982 CMLD2_000146 CCOC(=O)C1=NO[C@@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H13 compound treatment 1.88023E7 -66000.0 0.0 -0.0044 -1.0 3011265 CMLD2_000147 OC(C1CCCCC1)C2=CCCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H14 compound treatment 3.01049E7 1.12E7 0.75 0.7546 1.0 3011266 CMLD2_000148 OC(C1=CCCCC1=O)c2ccc(cc2)[N+](=O)[O-] 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H15 compound treatment 3.45956E7 1.57E7 1.06 1.0562 1.0 3131983 CMLD2_000149 CC1(C)O[C@H]2OC([C@H](O)CON3C(=O)c4ccccc4C3=O)[C@H](O)[C@H]2O1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H16 compound treatment 1.06063E7 -8260000.0 -0.55 -0.5548 -1.0 3011267 CMLD2_000150 COCOc1ccc(Br)cc1C(=O)[C@@H]2O[C@H]2c3cccc(OC)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H17 compound treatment 5.03045E7 3.14E7 2.11 2.1111 1.0 3131984 CMLD2_000151 C[C@@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@]42[C@H]5O[C@H](C)[C@@H]([C@@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H18 compound treatment 1.98689E8 1.8E8 12.08 12.076 1.0 3011268 CMLD2_000152 COc1ccc(C#C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H19 mock treatment 3.13604E7 1.25E7 0.84 0.8389 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H20 mock treatment 8990400.0 -9880000.0 -0.66 -0.6634 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H21 compound treatment 3.35897E7 1.47E7 0.99 0.9886 1.0 3131985 CMLD2_000153 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H22 compound treatment 6.20176E7 4.31E7 2.9 2.8977 1.0 3131715 CMLD2_000154 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H23 compound treatment 3.03896E7 1.15E7 0.77 0.7737 1.0 3011247 CMLD2_000155 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 H24 compound treatment 1.14172E7 -7450000.0 -0.5 -0.5004 -1.0 3131986 CMLD2_000156 COC(=O)C1=C(C)N(Cc2ccccc2)c3c(C(=O)OC)c(C(=O)OC)c(C(=O)OC)c(=O)n3[C@@H]1c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I01 compound treatment 1.07565E7 -8110000.0 -0.54 -0.5447 -1.0 3131987 CMLD2_000157 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I02 compound treatment 2.32035E7 4340000.0 0.29 0.2911 1.0 3011269 CMLD2_000158 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3cccc4ccccc34)O1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I03 compound treatment 2.17346E7 2870000.0 0.19 0.1925 1.0 3131988 CMLD2_000159 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I04 compound treatment 7055600.0 -1.18E7 -0.79 -0.7933 -1.0 3011270 CMLD2_000160 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I05 mock treatment 1.63241E7 -2540000.0 -0.17 -0.1709 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I06 mock treatment 3.53445E7 1.65E7 1.11 1.1065 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I07 compound treatment 1.63264E7 -2540000.0 -0.17 -0.1707 -1.0 3422373 CMLD2_000161 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I08 compound treatment 8959330.0 -9910000.0 -0.67 -0.6654 -1.0 3011271 CMLD2_000162 COC(=O)NC/C=C\c1nc(CCCO)co1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I09 compound treatment 1.58898E7 -2980000.0 -0.2 -0.2 -1.0 3131989 CMLD2_000163 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I10 compound treatment 2.07801E7 1910000.0 0.13 0.1284 1.0 3011272 CMLD2_000164 CO[C@@H]1[C@@H](C)/C(=C\CC(=O)OC)/c2ccccc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I11 compound treatment 1.69405E7 -1930000.0 -0.13 -0.1295 -1.0 3131990 CMLD2_000165 CC(=NOCc1ccc(cc1)c2cc(no2)c3ccccc3)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I12 compound treatment 7338350.0 -1.15E7 -0.77 -0.7743 -1.0 3131991 CMLD2_000166 COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I13 compound treatment 2.00476E7 1180000.0 0.08 0.0792 1.0 3011273 CMLD2_000167 C=CC(=O)N1C(=O)c2ccccc2S1(=O)=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I14 compound treatment 1.14088E7 -7460000.0 -0.5 -0.5009 -1.0 3131992 CMLD2_000168 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#Cc3ccccc3)cc2)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I15 compound treatment 8897280.0 -9970000.0 -0.67 -0.6696 -1.0 3011274 CMLD2_000169 CC(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I16 mock treatment 2.35688E7 4700000.0 0.32 0.3157 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I17 compound treatment 3.09962E8 2.91E8 19.55 19.5486 1.0 3131993 CMLD2_000170 C[C@H]1OC=C2[C@H](O)C3O[C@@H]3/C(=N\OCc4ccccc4)/[C@@]52[C@H]6OC(C)[C@@H](C15)C7=C6[C@H](O)[C@H]8O[C@H]8C7=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I18 compound treatment 2.13074E7 2440000.0 0.16 0.1638 1.0 3011312 CMLD2_000171 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I19 compound treatment 1.15099E7 -7360000.0 -0.49 -0.4942 -1.0 3131989 CMLD2_000172 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I20 compound treatment 2.13913E7 2520000.0 0.17 0.1694 1.0 3011257 CMLD2_000173 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I21 mock treatment 1.77544E7 -1110000.0 -0.07 -0.0748 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I22 mock treatment 2.52399E7 6370000.0 0.43 0.4279 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I23 compound treatment 2.42174E7 5350000.0 0.36 0.3592 1.0 3132111 CMLD2_000174 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(NC(=O)C)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(NC(=O)C)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 I24 compound treatment 1.32852E7 -5580000.0 -0.37 -0.3749 -1.0 3131703 CMLD2_000175 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J01 compound treatment 1.52136E7 -3650000.0 -0.25 -0.2454 -1.0 3132112 CMLD2_000176 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J02 compound treatment 1.31144E7 -5750000.0 -0.39 -0.3864 -1.0 3011347 CMLD2_000177 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J03 compound treatment 6028540.0 -1.28E7 -0.86 -0.8623 -1.0 3132113 CMLD2_000178 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J04 compound treatment 1.78789E7 -989000.0 -0.07 -0.0664 -1.0 3132114 CMLD2_000179 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J05 mock treatment 2.18807E7 3010000.0 0.2 0.2023 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J06 mock treatment 2.46854E7 5820000.0 0.39 0.3907 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J07 compound treatment 1.87443E7 -124000.0 -0.01 -0.0083 -1.0 3011348 CMLD2_000180 CC(C)C[C@H](NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45)C(=O)NCC(c6ccccc6)c7ccccc7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J08 compound treatment 4.19867E7 2.31E7 1.55 1.5525 1.0 3132115 CMLD2_000181 CO[C@H]1C[C@@H]2C[C@H](CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2)OC(=O)\C=C/CCc4coc(\C=C/CNC(=O)OC)n4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J09 compound treatment 1.71318E7 -1740000.0 -0.12 -0.1166 -1.0 3011349 CMLD2_000182 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J10 compound treatment 9065540.0 -9800000.0 -0.66 -0.6583 -1.0 3132116 CMLD2_000183 CO[C@@H](C(C)C)[C@@H](C)C1OC(=O)CC1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J11 compound treatment 2.42145E7 5350000.0 0.36 0.359 1.0 3132117 CMLD2_000184 COC(=O)[C@@H]1[C@@H](c2ccccc2)[C@](Oc3ccccc3C1=O)(C(=O)OC)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J12 compound treatment 3.91937E7 2.03E7 1.36 1.365 1.0 3011350 CMLD2_000185 CC(=NOCc1cccc(c1)c2cc(no2)c3ccccc3)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J13 compound treatment 1.75664E7 -1300000.0 -0.09 -0.0874 -1.0 3132118 CMLD2_000186 CC(C)C(=O)N[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J14 compound treatment 4.23085E7 2.34E7 1.57 1.5741 1.0 3011352 CMLD2_000187 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C=C)cc2)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J15 compound treatment 1.50856E7 -3780000.0 -0.25 -0.254 -1.0 3132119 CMLD2_000188 CO[C@H](CO)COc1ccc(OC)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J16 compound treatment 8664100.0 -1.02E7 -0.69 -0.6853 -1.0 3011353 CMLD2_000189 Oc1ccccc1C(=O)/C=C/c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J17 compound treatment 2.02054E7 1340000.0 0.09 0.0898 1.0 3132120 CMLD2_000190 CC(=NOCc1ccc(cc1)c2cn(nn2)[C@@H]3COC[C@H]3O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J18 compound treatment 5.25601E7 3.37E7 2.26 2.2626 1.0 3011354 CMLD2_000191 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CC(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J19 compound treatment 1.64541E7 -2410000.0 -0.16 -0.1621 -1.0 3132121 CMLD2_000192 C[C@@H]1CC[C@@H]2N(CC(COCC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J20 compound treatment 2.97309E7 1.09E7 0.73 0.7295 1.0 3011355 CMLD2_000193 CC(C)CCN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J21 mock treatment 1.87905E7 -77800.0 -0.01 -0.0052 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J22 mock treatment 1.57808E7 -3090000.0 -0.21 -0.2073 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J23 compound treatment 1138620.0 -1.77E7 -1.19 -1.1906 -1.0 3132122 CMLD2_000194 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(Br)c3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5cccc(c5)N6CCOCC6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 J24 compound treatment 1.76734E7 -1190000.0 -0.08 -0.0802 -1.0 3132123 CMLD2_000195 CCC(=O)[C@@]1(O[C@@]23[C@H]4[C@@H]1CCOC4=O)C(=O)N3[C@@H](C(=C(C)N2Cc5ccccc5)C(=O)OC)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K01 compound treatment 8836560.0 -1.0E7 -0.67 -0.6737 -1.0 3132124 CMLD2_000196 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K02 compound treatment 1.16497E7 -7220000.0 -0.48 -0.4848 -1.0 3011357 CMLD2_000197 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K03 compound treatment 7706590.0 -1.12E7 -0.75 -0.7496 -1.0 3132125 CMLD2_000198 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K04 compound treatment 2.31273E7 4260000.0 0.29 0.286 1.0 3132126 CMLD2_000199 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCCc6ccc(F)cc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K05 compound treatment 1.71583E7 -1710000.0 -0.11 -0.1148 -1.0 3011359 CMLD2_000200 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K06 compound treatment 3.32914E7 1.44E7 0.97 0.9686 1.0 3132127 CMLD2_000201 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K07 mock treatment 2.79348E7 9070000.0 0.61 0.6089 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K08 mock treatment 1.49718E7 -3900000.0 -0.26 -0.2617 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K09 compound treatment 1.16231E7 -7250000.0 -0.49 -0.4866 -1.0 3011360 CMLD2_000202 COc1cccc(c1)[C@H](O)Cn2cc(nn2)c3ccc(CON=C(C)C)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K10 compound treatment 7695330.0 -1.12E7 -0.75 -0.7503 -1.0 3132128 CMLD2_000203 Cc1ccc2[nH]c3nc(CCCn4ccnc4c5ccccc5)nnc3c2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K11 compound treatment 3.01716E7 1.13E7 0.76 0.7591 1.0 3011361 CMLD2_000204 COC(=O)C1=C(C)[C@@H](O)[C@@H](C)[C@@H](O1)c2c(OC)c(OC)c(C)c(OC)c2OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K12 compound treatment 1.21112E9 1.19E9 80.07 80.0663 1.0 3132129 CMLD2_000205 C[C@H]1OC=C2[C@H](OC(=O)C)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](O)[C@H]7O[C@H]7C6=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K13 compound treatment 1.37939E7 -5070000.0 -0.34 -0.3408 -1.0 3011362 CMLD2_000206 CO[C@H]1C[C@@H]2C[C@H](O)CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K14 compound treatment 2.00059E7 1140000.0 0.08 0.0764 1.0 3011258 CMLD2_000207 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K15 mock treatment 2.0155E7 1290000.0 0.09 0.0864 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K16 mock treatment 3135550.0 -1.57E7 -1.06 -1.0565 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K17 compound treatment 6.53141E7 4.64E7 3.12 3.1191 1.0 3132248 CMLD2_000208 CCN1C(=O)[C@H]2CC=C3[C@H]([C@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C53OCCCO5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K18 compound treatment 1.55709E7 -3300000.0 -0.22 -0.2214 -1.0 3011363 CMLD2_000209 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K19 compound treatment 2.91268E7 1.03E7 0.69 0.6889 1.0 3132249 CMLD2_000210 C[C@@H]1CC[C@@H]2N(CC(COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K20 compound treatment 5.07966E7 3.19E7 2.14 2.1442 1.0 3011399 CMLD2_000211 CCCCc1nc2CCN(CCC(C)C)Cc2c3CO[C@@H](C)Cc13 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K21 compound treatment 1.96512E7 783000.0 0.05 0.0526 1.0 3132250 CMLD2_000212 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K22 compound treatment 2.51653E7 6300000.0 0.42 0.4229 1.0 3011400 CMLD2_000213 C[C@@H]1CC[C@H](N[C@H]1c2ccc(cc2)c3ccco3)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K23 mock treatment 1.67405E7 -2130000.0 -0.14 -0.1429 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 K24 mock treatment 2.96702E7 1.08E7 0.73 0.7254 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L01 compound treatment 2.2896E7 4030000.0 0.27 0.2705 1.0 3132251 CMLD2_000214 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L02 compound treatment 1.84696E7 -399000.0 -0.03 -0.0268 -1.0 3132252 CMLD2_000215 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L03 compound treatment 1.32971E7 -5570000.0 -0.37 -0.3741 -1.0 3011402 CMLD2_000216 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L04 compound treatment 1.60204E7 -2850000.0 -0.19 -0.1912 -1.0 3132253 CMLD2_000217 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L05 compound treatment 1.19412E7 -6930000.0 -0.47 -0.4652 -1.0 3132254 CMLD2_000218 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L06 compound treatment 2.52068E7 6340000.0 0.43 0.4257 1.0 3011403 CMLD2_000219 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L07 mock treatment 1.03904E7 -8480000.0 -0.57 -0.5693 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L08 mock treatment 2.371E7 4840000.0 0.33 0.3251 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L09 compound treatment 1.99714E7 1100000.0 0.07 0.0741 1.0 3132255 CMLD2_000220 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L10 compound treatment 2.00719E7 1200000.0 0.08 0.0808 1.0 3132256 CMLD2_000221 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(C)c(C)cc45)CCCc3n2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L11 compound treatment 1.29444E7 -5920000.0 -0.4 -0.3978 -1.0 3011404 CMLD2_000222 CCOC(=O)C1=NO[C@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L12 compound treatment 1.34072E7 -5460000.0 -0.37 -0.3667 -1.0 3011405 CMLD2_000223 OC(CCc1ccccc1)C2=CCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L13 compound treatment 1.91326E7 264000.0 0.02 0.0178 1.0 3132257 CMLD2_000224 OC(CCc1ccccc1)C23OC3CCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L14 compound treatment 1.80941E7 -774000.0 -0.05 -0.052 -1.0 3132258 CMLD2_000225 CCCNC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L15 mock treatment 1.04424E7 -8430000.0 -0.57 -0.5658 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L16 mock treatment 7062830.0 -1.18E7 -0.79 -0.7928 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L17 compound treatment 1.48304E7 -4040000.0 -0.27 -0.2712 -1.0 3011407 CMLD2_000226 C[C@H]1CC[C@@H]2N([C@@H]1c3ccccc3)C(=O)[C@@H](Cc4ccccc4)NC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L18 compound treatment 2.86467E8 2.68E8 17.97 17.9707 1.0 3132259 CMLD2_000227 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L19 compound treatment 3.06599E7 1.18E7 0.79 0.7919 1.0 3132260 CMLD2_000228 C[C@@H]1CC[C@@H]2N(CC(CN3C(=O)c4ccccc4C3=O)OC2=O)[C@H]1c5ccc(Br)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L20 compound treatment 3.03168E7 1.14E7 0.77 0.7688 1.0 3011408 CMLD2_000229 CC(C)CCN1CCc2nc(COc3ccccc3)c4C[C@H](C)OCc4c2C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L21 compound treatment 1.34372E7 -5430000.0 -0.36 -0.3647 -1.0 3132261 CMLD2_000230 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L22 compound treatment 2.65005E7 7630000.0 0.51 0.5125 1.0 3011409 CMLD2_000231 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#CCN(C)C)cc2)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L23 mock treatment 1.52335E7 -3630000.0 -0.24 -0.2441 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 L24 mock treatment 9528450.0 -9340000.0 -0.63 -0.6272 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M01 compound treatment 1.93034E7 435000.0 0.03 0.0292 1.0 3132262 CMLD2_000232 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc4ccccc34)O2)O1)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M02 compound treatment 1.31387E7 -5730000.0 -0.38 -0.3848 -1.0 3132263 CMLD2_000233 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M03 compound treatment 1.75668E7 -1300000.0 -0.09 -0.0874 -1.0 3011410 CMLD2_000234 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M04 compound treatment 1.33148E7 -5550000.0 -0.37 -0.3729 -1.0 3132264 CMLD2_000235 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M05 compound treatment 2.95903E7 1.07E7 0.72 0.72 1.0 3132265 CMLD2_000236 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M06 compound treatment 3.05212E7 1.17E7 0.78 0.7826 1.0 3011411 CMLD2_000237 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M07 compound treatment 1.63614E7 -2510000.0 -0.17 -0.1683 -1.0 3132266 CMLD2_000238 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccncc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M08 compound treatment 2.3149E7 4280000.0 0.29 0.2875 1.0 3011412 CMLD2_000239 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M09 mock treatment 1.89008E7 32500.0 0.0 0.0022 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M10 mock treatment 1.84045E7 -464000.0 -0.03 -0.0311 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M11 compound treatment 4.93542E7 3.05E7 2.05 2.0473 1.0 3132389 CMLD2_000240 COC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M12 compound treatment 1.64662E7 -2400000.0 -0.16 -0.1613 -1.0 3011413 CMLD2_000241 O=C1CCCC(C1)C2=CCCCC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M13 mock treatment 2.96821E7 1.08E7 0.73 0.7262 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M14 mock treatment 1.31572E7 -5710000.0 -0.38 -0.3835 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M15 compound treatment 1.86158E7 -252000.0 -0.02 -0.017 -1.0 3132390 CMLD2_000242 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCCc2nc1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M16 compound treatment 1.70266E7 -1840000.0 -0.12 -0.1237 -1.0 3011415 CMLD2_000243 CCO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M17 mock treatment 2.05114E7 1640000.0 0.11 0.1103 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M18 compound treatment 4.95073E7 3.06E7 2.06 2.0576 1.0 3132391 CMLD2_000244 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCC2CCCCC2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M19 compound treatment 1.7062E7 -1810000.0 -0.12 -0.1213 -1.0 3132392 CMLD2_000245 C[C@@H]1CC[C@@H]2N(CC(Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M20 compound treatment 8308690.0 -1.06E7 -0.71 -0.7091 -1.0 3011466 CMLD2_000246 COc1ccc(cc1)c2nc3CCN(CCC(C)C)Cc3c4CO[C@@H](C)Cc24 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M21 compound treatment 1.94457E7 577000.0 0.04 0.0388 1.0 3132393 CMLD2_000247 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCOC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M22 compound treatment 3.08234E7 1.2E7 0.8 0.8029 1.0 3011467 CMLD2_000248 C[C@H]1CC[C@H](N[C@@H]1c2cccc(c2)N3CCCC3=O)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M23 compound treatment 2.48069E7 5940000.0 0.4 0.3988 1.0 3132394 CMLD2_000249 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CCCN4C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 M24 compound treatment 2.2224E7 3360000.0 0.23 0.2254 1.0 3132261 CMLD2_000250 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N01 compound treatment 2.34494E7 4580000.0 0.31 0.3076 1.0 3132395 CMLD2_000251 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N02 compound treatment 5064750.0 -1.38E7 -0.93 -0.927 -1.0 3132396 CMLD2_000252 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N03 compound treatment 1.34931E7 -5380000.0 -0.36 -0.361 -1.0 3011471 CMLD2_000253 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N04 compound treatment 1.60175E7 -2850000.0 -0.19 -0.1914 -1.0 3132397 CMLD2_000254 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N05 compound treatment 8081420.0 -1.08E7 -0.72 -0.7244 -1.0 3011472 CMLD2_000255 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N06 compound treatment 1.14786E7 -7390000.0 -0.5 -0.4963 -1.0 3132398 CMLD2_000256 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5cccc6ccccc56 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N07 compound treatment 1.97617E7 893000.0 0.06 0.06 1.0 3132399 CMLD2_000257 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccc5OCOc5c4)O3)O2)OC(=O)NCc6cccc7ccccc67 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N08 compound treatment 1.19744E7 -6890000.0 -0.46 -0.463 -1.0 3011473 CMLD2_000258 Cc1ccc(cc1)S(=O)(=O)n2c3ccccc3c4nnc(nc24)C(=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N09 mock treatment 1.27298E7 -6140000.0 -0.41 -0.4122 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N10 mock treatment 3.95253E7 2.07E7 1.39 1.3872 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N11 compound treatment 1.3928E7 -4940000.0 -0.33 -0.3318 -1.0 3011475 CMLD2_000259 BrC1=CC(=C)[C@@H]2O[C@@H]2C31OCCCO3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N12 compound treatment 4.21001E7 2.32E7 1.56 1.5601 1.0 3132400 CMLD2_000260 CCCCOC(OCCCC)C(O)CSc1ccc2ccccc2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N13 mock treatment 1.86871E7 -181000.0 -0.01 -0.0122 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N14 mock treatment 2.73083E7 8440000.0 0.57 0.5668 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N15 compound treatment 1.50613E7 -3810000.0 -0.26 -0.2557 -1.0 3011477 CMLD2_000261 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N16 compound treatment 1.87967E7 -71600.0 0.0 -0.0048 -1.0 3132401 CMLD2_000262 CO[C@@H](C(C)C)[C@@H](C)C1OC1CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N17 compound treatment 0.0 -1.89E7 -1.27 -1.2671 -1.0 4845 CMLD2_000263 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3c(O[C@]2([C@@H]1c4ccccc4)c5ccc(OC)cc5)cc(OC)cc3OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N18 compound treatment 2.41973E7 5330000.0 0.36 0.3579 1.0 3011479 CMLD2_000264 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2cc(OC)c(OC)c(OC)c2)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N19 compound treatment 3.08246E7 1.2E7 0.8 0.8029 1.0 3132403 CMLD2_000265 C[C@H]1CC[C@@H]2N(CC(COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N20 compound treatment 1.44502E7 -4420000.0 -0.3 -0.2967 -1.0 3011480 CMLD2_000266 C[C@H]1Cc2c(nc3CCN(CCOc4ccccc4)Cc3c2CO1)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N21 compound treatment 2.30323E7 4160000.0 0.28 0.2796 1.0 3132404 CMLD2_000267 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N22 compound treatment 1.24318E7 -6440000.0 -0.43 -0.4322 -1.0 3011481 CMLD2_000268 C[C@@H]1CC[C@H](N[C@H]1c2ccc(NC(=O)C)cc2)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N23 compound treatment 1.55562E7 -3310000.0 -0.22 -0.2224 -1.0 3132405 CMLD2_000269 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@H](C(C)C)N(C)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 N24 compound treatment 1.75897E7 -1280000.0 -0.09 -0.0859 -1.0 3131577 CMLD2_000270 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O01 compound treatment 1.08171E7 -8050000.0 -0.54 -0.5407 -1.0 3132406 CMLD2_000271 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3cccc4ccccc34 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O02 compound treatment 1.80751E7 -793000.0 -0.05 -0.0533 -1.0 3132407 CMLD2_000272 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6ccc7OCOc7c6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O03 compound treatment 3.16227E7 1.28E7 0.86 0.8565 1.0 3011482 CMLD2_000273 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O04 compound treatment 1.16022E7 -7270000.0 -0.49 -0.488 -1.0 3132527 CMLD2_000274 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O05 compound treatment 1.64421E7 -2430000.0 -0.16 -0.1629 -1.0 3011483 CMLD2_000275 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O06 compound treatment 1.89266E7 58300.0 0.0 0.0039 1.0 3132528 CMLD2_000276 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O07 compound treatment 1.8648E7 -220000.0 -0.01 -0.0148 -1.0 3011485 CMLD2_000277 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O08 compound treatment 1.1199E7 -7670000.0 -0.52 -0.515 -1.0 3132529 CMLD2_000278 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O09 compound treatment 1.18276E7 -7040000.0 -0.47 -0.4728 -1.0 3011486 CMLD2_000279 COC(=O)[C@H]1O[C@H]([C@H](C)[C@@H](O)[C@H]1C)c2c(OC)c(OC)c(C)c(OC)c2OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O10 compound treatment 2.47211E8 2.28E8 15.33 15.3345 1.0 3132530 CMLD2_000280 OC(CCCCBr)C1=CCCCC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O11 mock treatment 3.05388E7 1.17E7 0.78 0.7837 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O12 mock treatment 3.01792E7 1.13E7 0.76 0.7596 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O13 compound treatment 1.29665E7 -5900000.0 -0.4 -0.3963 -1.0 3132531 CMLD2_000281 COC(=O)C/C=C/[C@H](C)[C@@H](OCc1ccccc1Br)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O14 compound treatment 1722660.0 -1.71E7 -1.15 -1.1514 -1.0 3011535 CMLD2_000282 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O15 compound treatment 3588380.0 -1.53E7 -1.03 -1.0261 -1.0 3132532 CMLD2_000283 Nc1ccccc1C(=O)/C=C/c2ccc3OCOc3c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O16 compound treatment 2.3898E7 5030000.0 0.34 0.3378 1.0 3131858 CMLD2_000284 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O17 mock treatment 1.97792E7 911000.0 0.06 0.0612 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O18 compound treatment 2.93697E7 1.05E7 0.71 0.7052 1.0 3011536 CMLD2_000285 OC[C@H]1O[C@@H](C=C[C@@H]1O)C#Cc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O19 compound treatment 0.0 -1.89E7 -1.27 -1.2671 -1.0 3132533 CMLD2_000286 C[C@H]1CC[C@@H]2N(C[C@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O20 compound treatment 8047300.0 -1.08E7 -0.73 -0.7267 -1.0 3011537 CMLD2_000287 C[C@H]1Cc2c(COc3ccccc3)nc4CCN(CCOc5ccccc5)Cc4c2CO1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O21 compound treatment 1.96467E7 778000.0 0.05 0.0523 1.0 3132534 CMLD2_000288 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O22 compound treatment 7605570.0 -1.13E7 -0.76 -0.7564 -1.0 3011538 CMLD2_000289 C[C@@H]1CC[C@H](N[C@H]1c2cccc(c2)N3CCOCC3)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O23 compound treatment 7055470.0 -1.18E7 -0.79 -0.7933 -1.0 3132535 CMLD2_000290 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)c3ccccc3)c4ccccc4)C(=O)OC)c5ccccc5)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 O24 compound treatment 1.68768E7 -1990000.0 -0.13 -0.1337 -1.0 3132250 CMLD2_000291 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P01 compound treatment 9380060.0 -9490000.0 -0.64 -0.6372 -1.0 3132536 CMLD2_000292 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P02 compound treatment 1.59608E7 -2910000.0 -0.2 -0.1953 -1.0 3132537 CMLD2_000293 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P03 compound treatment 1.28666E7 -6000000.0 -0.4 -0.403 -1.0 3011540 CMLD2_000294 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P04 compound treatment 1.89243E7 56000.0 0.0 0.0038 1.0 3132538 CMLD2_000295 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCCc5ccc(F)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P05 compound treatment 1.55219E7 -3350000.0 -0.22 -0.2247 -1.0 3011541 CMLD2_000296 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P06 compound treatment 3.90827E7 2.02E7 1.36 1.3575 1.0 3132539 CMLD2_000297 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P07 compound treatment 2.14582E7 2590000.0 0.17 0.1739 1.0 3011542 CMLD2_000298 CCN(CC)CC(O)CN1CCCCc2nc(C)c(C)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P08 compound treatment 4.08767E7 2.2E7 1.48 1.478 1.0 3131847 CMLD2_000299 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P09 compound treatment 2.5189E7 6320000.0 0.42 0.4245 1.0 3132540 CMLD2_000300 C[C@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5O[C@H](C)[C@@H]([C@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P10 compound treatment 1.03568E7 -8510000.0 -0.57 -0.5716 -1.0 3011543 CMLD2_000301 COCOc1ccc(Br)cc1C(=O)/C=C/c2ccc3OCOc3c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P11 mock treatment 1.90994E7 231000.0 0.02 0.0155 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P12 mock treatment 8680050.0 -1.02E7 -0.68 -0.6842 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P13 compound treatment 0.0 -1.89E7 -1.27 -1.2671 -1.0 3132541 CMLD2_000302 COC(OC)[C@@H](C)[C@H](OC)[C@@H](C)[C@H](OC)c1ccccc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P14 compound treatment 2.71616E7 8290000.0 0.56 0.5569 1.0 3011544 CMLD2_000303 CC(C)c1ccc(C)n1C(=O)OC(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P15 compound treatment 1.81716E7 -697000.0 -0.05 -0.0468 -1.0 3011545 CMLD2_000304 Brc1ccc(cc1)[C@@H]2OC(=O)C[C@@H]2c3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P16 compound treatment 1.53704E7 -3500000.0 -0.23 -0.2349 -1.0 3132542 CMLD2_000305 COC(=O)[C@H]1[C@@H](C(=O)[C@]2(O)c3ccccc3O[C@@]12c4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P17 mock treatment 1.55549E7 -3310000.0 -0.22 -0.2225 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P18 compound treatment 1.41868E7 -4680000.0 -0.31 -0.3144 -1.0 3132543 CMLD2_000306 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P19 compound treatment 1.20169E7 -6850000.0 -0.46 -0.4601 -1.0 3011546 CMLD2_000307 C[C@@H]1CCC2N(C[C@H](O)CN(Cc3ccccc3)C2=O)[C@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P20 compound treatment 2.67695E7 7900000.0 0.53 0.5306 1.0 3132544 CMLD2_000308 CCCCc1nc2CCN(CCOc3ccccc3)Cc2c4CO[C@@H](C)Cc14 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P21 compound treatment 1.6825E7 -2040000.0 -0.14 -0.1372 -1.0 3131978 CMLD2_000309 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P22 compound treatment 2.69647E7 8100000.0 0.54 0.5437 1.0 3011547 CMLD2_000310 COCC#Cc1ccc(cc1)[C@@H]2N[C@@H](CC[C@H]2C)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P23 compound treatment 9900500.0 -8970000.0 -0.6 -0.6022 -1.0 3132545 CMLD2_000311 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@@H]4CC[C@H](C)[C@H](N4C3=O)c5cccc(OC)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2109 P24 compound treatment 2.98239E7 1.1E7 0.74 0.7357 1.0 3132534 CMLD2_000312 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A01 compound treatment 2.52669E7 7310000.0 0.49 0.491 1.0 3132546 CMLD2_000313 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A02 compound treatment 2.24772E7 4520000.0 0.3 0.3036 1.0 3011548 CMLD2_000314 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A03 compound treatment 5674180.0 -1.23E7 -0.82 -0.8248 -1.0 3130471 CMLD2_000315 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A04 compound treatment 1.75416E7 -414000.0 -0.03 -0.0278 -1.0 3130472 CMLD2_000316 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A05 compound treatment 4726980.0 -1.32E7 -0.89 -0.8884 -1.0 3011549 CMLD2_000317 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A06 compound treatment 1.01534E7 -7800000.0 -0.52 -0.524 -1.0 3011597 CMLD2_000318 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A07 compound treatment 3579970.0 -1.44E7 -0.97 -0.9654 -1.0 3130473 CMLD2_000319 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A08 compound treatment 9871970.0 -8080000.0 -0.54 -0.5429 -1.0 3010878 CMLD2_000320 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A09 compound treatment 1.38161E7 -4140000.0 -0.28 -0.278 -1.0 3130474 CMLD2_000321 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A10 compound treatment 1.33921E7 -4560000.0 -0.31 -0.3065 -1.0 3010879 CMLD2_000322 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A11 compound treatment 8770720.0 -9190000.0 -0.62 -0.6168 -1.0 3130475 CMLD2_000323 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A12 compound treatment 2.19659E7 4010000.0 0.27 0.2693 1.0 3130476 CMLD2_000324 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A13 mock treatment 3.5403E7 1.74E7 1.17 1.1717 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A14 mock treatment 1.58428E7 -2110000.0 -0.14 -0.1419 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A15 compound treatment 1583870.0 -1.64E7 -1.1 -1.0995 -1.0 3010880 CMLD2_000325 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A16 compound treatment 1.97041E7 1750000.0 0.12 0.1174 1.0 3130477 CMLD2_000326 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A17 compound treatment 7.82751E7 6.03E7 4.05 4.0508 1.0 3010881 CMLD2_000327 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C5CCCCC5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A18 compound treatment 2.37599E7 5800000.0 0.39 0.3898 1.0 3130478 CMLD2_000328 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A19 compound treatment 5528820.0 -1.24E7 -0.83 -0.8346 -1.0 3130479 CMLD2_000329 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A20 compound treatment 2531700.0 -1.54E7 -1.04 -1.0358 -1.0 3010882 CMLD2_000330 C[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H](C)NC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A21 compound treatment 8781300.0 -9170000.0 -0.62 -0.6161 -1.0 3130480 CMLD2_000331 C[C@H]/1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C\C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A22 compound treatment 1.2013E7 -5940000.0 -0.4 -0.3991 -1.0 3010883 CMLD2_000332 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc3ccccc3)\C=C\[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A23 compound treatment 1.91587E7 1200000.0 0.08 0.0808 1.0 3130481 CMLD2_000333 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 A24 compound treatment 1516660.0 -1.64E7 -1.1 -1.104 -1.0 3130482 CMLD2_000334 C[C@@H]1/C=C/CC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2O)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B01 compound treatment 1.23372E7 -5620000.0 -0.38 -0.3773 -1.0 3010884 CMLD2_000335 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B02 compound treatment 2.99821E7 1.2E7 0.81 0.8076 1.0 3130483 CMLD2_000336 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B03 compound treatment 2.0139E7 2180000.0 0.15 0.1466 1.0 3130484 CMLD2_000337 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B04 compound treatment 8839600.0 -9120000.0 -0.61 -0.6122 -1.0 3010885 CMLD2_000338 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B05 compound treatment 3738930.0 -1.42E7 -0.95 -0.9548 -1.0 3130485 CMLD2_000339 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B06 compound treatment 8.38721E7 6.59E7 4.43 4.4266 1.0 3010886 CMLD2_000340 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B07 compound treatment 1.25831E7 -5370000.0 -0.36 -0.3608 -1.0 3130486 CMLD2_000341 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B08 compound treatment 1.99904E7 2030000.0 0.14 0.1366 1.0 3130487 CMLD2_000342 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B09 compound treatment 6502450.0 -1.15E7 -0.77 -0.7692 -1.0 3010887 CMLD2_000343 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B10 compound treatment 7190220.0 -1.08E7 -0.72 -0.723 -1.0 3130488 CMLD2_000344 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B11 compound treatment 4318820.0 -1.36E7 -0.92 -0.9158 -1.0 3010888 CMLD2_000345 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B12 compound treatment 1.78629E7 -93100.0 -0.01 -0.0063 -1.0 3130489 CMLD2_000346 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B13 mock treatment 2.69371E7 8980000.0 0.6 0.6031 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B14 mock treatment 1957660.0 -1.6E7 -1.07 -1.0744 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B15 compound treatment 8389600.0 -9570000.0 -0.64 -0.6424 -1.0 3130616 CMLD2_000347 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCc6ccccc6)n3c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B16 compound treatment 9832940.0 -8120000.0 -0.55 -0.5455 -1.0 3010889 CMLD2_000348 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B17 compound treatment 3.20379E8 3.02E8 20.31 20.3094 1.0 3130617 CMLD2_000349 CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B18 compound treatment 1.6063E7 -1890000.0 -0.13 -0.1271 -1.0 3010924 CMLD2_000350 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B19 compound treatment 1.22447E7 -5710000.0 -0.38 -0.3835 -1.0 3130618 CMLD2_000351 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B20 compound treatment 1.16055E7 -6350000.0 -0.43 -0.4265 -1.0 3130619 CMLD2_000352 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B21 compound treatment 1.31484E7 -4810000.0 -0.32 -0.3229 -1.0 3010926 CMLD2_000353 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B22 compound treatment 3.00957E7 1.21E7 0.82 0.8152 1.0 3130620 CMLD2_000354 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B23 compound treatment 2.61073E7 8150000.0 0.55 0.5474 1.0 3130621 CMLD2_000355 C[C@@H]/1COC(=O)N[C@@H](C)C(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 B24 compound treatment 1.93821E7 1430000.0 0.1 0.0958 1.0 3010928 CMLD2_000356 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]3O[C@H](COC1=O)[C@@H](O)C=C3)[C@@H](O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C01 compound treatment 1.49497E7 -3010000.0 -0.2 -0.2019 -1.0 3130622 CMLD2_000357 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C02 compound treatment 1.38494E7 -4110000.0 -0.28 -0.2758 -1.0 3130623 CMLD2_000358 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C03 compound treatment 8016960.0 -9940000.0 -0.67 -0.6675 -1.0 3010930 CMLD2_000359 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C04 compound treatment 1.07533E7 -7200000.0 -0.48 -0.4837 -1.0 3130624 CMLD2_000360 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C05 compound treatment 8518130.0 -9440000.0 -0.63 -0.6338 -1.0 3010931 CMLD2_000361 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C06 compound treatment 1.55331E7 -2420000.0 -0.16 -0.1627 -1.0 3130625 CMLD2_000362 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C07 compound treatment 1.11189E7 -6840000.0 -0.46 -0.4592 -1.0 3130626 CMLD2_000363 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C08 compound treatment 3.22623E7 1.43E7 0.96 0.9607 1.0 3010932 CMLD2_000364 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C09 compound treatment 2.8985E7 1.1E7 0.74 0.7407 1.0 3130627 CMLD2_000365 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C10 compound treatment 1.05374E7 -7420000.0 -0.5 -0.4982 -1.0 3010933 CMLD2_000366 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C11 mock treatment 3.48743E7 1.69E7 1.14 1.1362 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C12 mock treatment 1.16739E7 -6280000.0 -0.42 -0.4219 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C13 compound treatment 1.20259E7 -5930000.0 -0.4 -0.3982 -1.0 3130628 CMLD2_000367 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C14 compound treatment 1.79659E7 9870.0 0.0 7.0E-4 1.0 3010934 CMLD2_000368 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C15 mock treatment 2.23063E7 4350000.0 0.29 0.2921 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C16 mock treatment 1.4598E7 -3360000.0 -0.23 -0.2255 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C17 compound treatment 3.1975E7 1.4E7 0.94 0.9415 1.0 3130629 CMLD2_000369 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C18 compound treatment 1.54932E7 -2460000.0 -0.17 -0.1654 -1.0 3130630 CMLD2_000370 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C19 compound treatment 1.82743E7 318000.0 0.02 0.0214 1.0 3010935 CMLD2_000371 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C20 compound treatment 2.53096E7 7350000.0 0.49 0.4938 1.0 3130631 CMLD2_000372 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C21 compound treatment 6136430.0 -1.18E7 -0.79 -0.7938 -1.0 3010936 CMLD2_000373 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C22 compound treatment 9036340.0 -8920000.0 -0.6 -0.599 -1.0 3130632 CMLD2_000374 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C23 compound treatment 2.89688E7 1.1E7 0.74 0.7396 1.0 3130633 CMLD2_000375 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 C24 compound treatment 1.95536E7 1600000.0 0.11 0.1073 1.0 3010937 CMLD2_000376 C[C@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D01 compound treatment 1.46896E7 -3270000.0 -0.22 -0.2194 -1.0 3130634 CMLD2_000377 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D02 compound treatment 6282740.0 -1.17E7 -0.78 -0.7839 -1.0 3010938 CMLD2_000378 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D03 compound treatment 1.49774E7 -2980000.0 -0.2 -0.2 -1.0 3130635 CMLD2_000379 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D04 compound treatment 1.09825E7 -6970000.0 -0.47 -0.4683 -1.0 3130759 CMLD2_000380 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D05 compound treatment 1.95075E7 1550000.0 0.1 0.1042 1.0 3010939 CMLD2_000381 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D06 compound treatment 2.26631E7 4710000.0 0.32 0.3161 1.0 3130760 CMLD2_000382 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D07 compound treatment 6617980.0 -1.13E7 -0.76 -0.7614 -1.0 3130761 CMLD2_000383 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D08 compound treatment 2.58354E7 7880000.0 0.53 0.5291 1.0 3130762 CMLD2_000384 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D09 compound treatment 1.2967E7 -4990000.0 -0.34 -0.335 -1.0 3010981 CMLD2_000385 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D10 compound treatment 2.15785E7 3620000.0 0.24 0.2433 1.0 3130763 CMLD2_000386 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D11 mock treatment 4.65558E7 2.86E7 1.92 1.9206 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D12 mock treatment 1.08315E7 -7120000.0 -0.48 -0.4785 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D13 compound treatment 2.79628E7 1.0E7 0.67 0.672 1.0 3130764 CMLD2_000387 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D14 compound treatment 3.42524E7 1.63E7 1.09 1.0944 1.0 3010983 CMLD2_000388 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D15 mock treatment 8162860.0 -9790000.0 -0.66 -0.6577 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D16 mock treatment 9477310.0 -8480000.0 -0.57 -0.5694 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D17 compound treatment 2.90118E7 1.11E7 0.74 0.7425 1.0 3130765 CMLD2_000389 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D18 compound treatment 1.61808E7 -1780000.0 -0.12 -0.1192 -1.0 3010984 CMLD2_000390 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D19 compound treatment 2.52715E7 7320000.0 0.49 0.4913 1.0 3130766 CMLD2_000391 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D20 compound treatment 1.71937E7 -762000.0 -0.05 -0.0512 -1.0 3010985 CMLD2_000392 CO[C@@H]1/C=C/CC(=O)N[C@@H](C)C(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D21 compound treatment 5842690.0 -1.21E7 -0.81 -0.8135 -1.0 3130767 CMLD2_000393 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D22 compound treatment 1.56058E7 -2350000.0 -0.16 -0.1578 -1.0 3130768 CMLD2_000394 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D23 compound treatment 5423890.0 -1.25E7 -0.84 -0.8416 -1.0 3130619 CMLD2_000395 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 D24 compound treatment 6905020.0 -1.11E7 -0.74 -0.7421 -1.0 3010986 CMLD2_000396 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E01 mock treatment 1.3554E7 -4400000.0 -0.3 -0.2956 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E02 mock treatment 2.78712E7 9920000.0 0.67 0.6659 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E03 compound treatment 9801120.0 -8150000.0 -0.55 -0.5476 -1.0 3130769 CMLD2_000397 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E04 compound treatment 1.9774E7 1820000.0 0.12 0.1221 1.0 3130770 CMLD2_000398 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E05 compound treatment 6314480.0 -1.16E7 -0.78 -0.7818 -1.0 3010987 CMLD2_000399 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E06 compound treatment 4856930.0 -1.31E7 -0.88 -0.8797 -1.0 3130771 CMLD2_000400 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E07 compound treatment 9016590.0 -8940000.0 -0.6 -0.6003 -1.0 3130772 CMLD2_000401 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E08 compound treatment 8354450.0 -9600000.0 -0.64 -0.6448 -1.0 3010988 CMLD2_000402 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E09 mock treatment 2.43369E7 6380000.0 0.43 0.4285 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E10 mock treatment 1.30875E7 -4870000.0 -0.33 -0.3269 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E11 compound treatment 2.99471E7 1.2E7 0.81 0.8053 1.0 3130773 CMLD2_000403 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E12 compound treatment 2.98497E7 1.19E7 0.8 0.7987 1.0 3010989 CMLD2_000404 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E13 compound treatment 1.74553E7 -501000.0 -0.03 -0.0336 -1.0 3130774 CMLD2_000405 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E14 compound treatment 6700590.0 -1.13E7 -0.76 -0.7559 -1.0 3130775 CMLD2_000406 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E15 compound treatment 1.77436E7 -212000.0 -0.01 -0.0143 -1.0 3010990 CMLD2_000407 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCC(C)C)n3c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E16 compound treatment 1.01503E7 -7810000.0 -0.52 -0.5242 -1.0 3130776 CMLD2_000408 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E17 mock treatment 1.5175E7 -2780000.0 -0.19 -0.1868 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E18 mock treatment 1.22835E7 -5670000.0 -0.38 -0.3809 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E19 compound treatment 2.83249E7 1.04E7 0.7 0.6963 1.0 3010991 CMLD2_000409 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E20 compound treatment 6327460.0 -1.16E7 -0.78 -0.7809 -1.0 3130777 CMLD2_000410 C[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E21 compound treatment 7386380.0 -1.06E7 -0.71 -0.7098 -1.0 3130778 CMLD2_000411 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E22 compound treatment 2.72518E7 9300000.0 0.62 0.6243 1.0 3010992 CMLD2_000412 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E23 compound treatment 1.38612E7 -4090000.0 -0.27 -0.275 -1.0 3130904 CMLD2_000413 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C)NS(=O)(=O)c3ccc(C)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 E24 compound treatment 1.69661E7 -990000.0 -0.07 -0.0665 -1.0 3130905 CMLD2_000414 CO[C@@H]1COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F01 mock treatment 8195140.0 -9760000.0 -0.66 -0.6555 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F02 mock treatment 1.92601E7 1300000.0 0.09 0.0876 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F03 compound treatment 3.04612E7 1.25E7 0.84 0.8398 1.0 3010993 CMLD2_000415 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F04 compound treatment 1.81764E7 220000.0 0.01 0.0148 1.0 3130906 CMLD2_000416 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F05 compound treatment 2.31957E7 5240000.0 0.35 0.3519 1.0 3130907 CMLD2_000417 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F06 compound treatment 2.17585E7 3800000.0 0.26 0.2554 1.0 3011036 CMLD2_000418 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F07 compound treatment 1.77573E7 -199000.0 -0.01 -0.0133 -1.0 3130908 CMLD2_000419 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F08 compound treatment 2.00491E7 2090000.0 0.14 0.1406 1.0 3130909 CMLD2_000420 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F09 mock treatment 3.39119E7 1.6E7 1.07 1.0715 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F10 mock treatment 1.68858E7 -1070000.0 -0.07 -0.0719 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F11 compound treatment 2.14956E7 3540000.0 0.24 0.2377 1.0 3011038 CMLD2_000421 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F12 compound treatment 6759470.0 -1.12E7 -0.75 -0.7519 -1.0 3130910 CMLD2_000422 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F13 compound treatment 1.33777E7 -4580000.0 -0.31 -0.3075 -1.0 3011039 CMLD2_000423 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F14 compound treatment 8263470.0 -9690000.0 -0.65 -0.6509 -1.0 3130911 CMLD2_000424 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F15 compound treatment 4.35182E7 2.56E7 1.72 1.7166 1.0 3130912 CMLD2_000425 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC\C=C(/C)\CCC=C(C)C)n3c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F16 compound treatment 1.92841E7 1330000.0 0.09 0.0892 1.0 3011040 CMLD2_000426 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F17 mock treatment 9979250.0 -7980000.0 -0.54 -0.5357 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F18 mock treatment 1.15987E7 -6360000.0 -0.43 -0.4269 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F19 compound treatment 1.8397E7 441000.0 0.03 0.0296 1.0 3011041 CMLD2_000427 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F20 compound treatment 2.11029E7 3150000.0 0.21 0.2113 1.0 3130913 CMLD2_000428 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F21 compound treatment 9630660.0 -8330000.0 -0.56 -0.5591 -1.0 3130914 CMLD2_000429 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F22 compound treatment 5784770.0 -1.22E7 -0.82 -0.8174 -1.0 3011043 CMLD2_000430 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC1=O)[C@H](O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F23 compound treatment 1.1185E7 -6770000.0 -0.45 -0.4547 -1.0 3130915 CMLD2_000431 CO[C@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 F24 compound treatment 1.87487E7 793000.0 0.05 0.0532 1.0 3011044 CMLD2_000432 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G01 compound treatment 1.57093E7 -2250000.0 -0.15 -0.1509 -1.0 3130916 CMLD2_000433 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G02 compound treatment 4267650.0 -1.37E7 -0.92 -0.9193 -1.0 3130917 CMLD2_000434 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G03 mock treatment 1.23237E7 -5630000.0 -0.38 -0.3782 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G04 mock treatment 1.89164E7 960000.0 0.06 0.0645 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G05 compound treatment 2.73858E7 9430000.0 0.63 0.6333 1.0 3011046 CMLD2_000435 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G06 compound treatment 5750690.0 -1.22E7 -0.82 -0.8197 -1.0 3130918 CMLD2_000436 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G07 compound treatment 1.94184E7 1460000.0 0.1 0.0982 1.0 3130919 CMLD2_000437 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G08 compound treatment 8816660.0 -9140000.0 -0.61 -0.6138 -1.0 3011047 CMLD2_000438 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G09 compound treatment 7998640.0 -9960000.0 -0.67 -0.6687 -1.0 3130920 CMLD2_000439 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G10 compound treatment 3.50512E7 1.71E7 1.15 1.148 1.0 3011048 CMLD2_000440 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G11 compound treatment 1.01799E7 -7780000.0 -0.52 -0.5222 -1.0 3130921 CMLD2_000441 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G12 compound treatment 2.24633E7 4510000.0 0.3 0.3027 1.0 3131048 CMLD2_000442 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G13 compound treatment 1.69848E7 -971000.0 -0.07 -0.0652 -1.0 3011049 CMLD2_000443 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G14 compound treatment 3.23048E7 1.43E7 0.96 0.9636 1.0 3131049 CMLD2_000444 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(CC)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G15 compound treatment 1.28987E7 -5060000.0 -0.34 -0.3396 -1.0 3011050 CMLD2_000445 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCCCC#C)n3c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G16 compound treatment 3.49285E8 3.31E8 22.25 22.2506 1.0 3131050 CMLD2_000446 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccccc5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G17 compound treatment 1.83913E7 435000.0 0.03 0.0292 1.0 3131051 CMLD2_000447 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G18 compound treatment 2.81554E7 1.02E7 0.68 0.6849 1.0 3011052 CMLD2_000448 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G19 mock treatment 3.01589E7 1.22E7 0.82 0.8195 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G20 mock treatment 1.83584E7 402000.0 0.03 0.027 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G21 compound treatment 2.41203E7 6160000.0 0.41 0.414 1.0 3131052 CMLD2_000449 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C\C=C\[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G22 compound treatment 1.99793E7 2020000.0 0.14 0.1359 1.0 3011053 CMLD2_000450 C[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G23 compound treatment 6558480.0 -1.14E7 -0.77 -0.7654 -1.0 3131053 CMLD2_000451 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@@H]3CCCN3C1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 G24 compound treatment 2.13809E7 3420000.0 0.23 0.23 1.0 3131054 CMLD2_000452 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H01 compound treatment 2.0024E7 2070000.0 0.14 0.1389 1.0 3011098 CMLD2_000453 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H02 compound treatment 8501730.0 -9450000.0 -0.63 -0.6349 -1.0 3131055 CMLD2_000454 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H03 mock treatment 1.19146E7 -6040000.0 -0.41 -0.4057 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H04 mock treatment 8271340.0 -9680000.0 -0.65 -0.6504 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H05 compound treatment 1.50283E7 -2930000.0 -0.2 -0.1966 -1.0 3131056 CMLD2_000455 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H06 compound treatment 1.98256E7 1870000.0 0.13 0.1256 1.0 3011099 CMLD2_000456 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H07 compound treatment 6669710.0 -1.13E7 -0.76 -0.7579 -1.0 3131057 CMLD2_000457 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H08 compound treatment 1.73308E7 -625000.0 -0.04 -0.042 -1.0 3011100 CMLD2_000458 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H09 compound treatment 2.00273E7 2070000.0 0.14 0.1391 1.0 3131058 CMLD2_000459 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H10 compound treatment 8029740.0 -9930000.0 -0.67 -0.6666 -1.0 3131059 CMLD2_000460 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H11 compound treatment 2.28206E7 4860000.0 0.33 0.3267 1.0 3011101 CMLD2_000461 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H12 compound treatment 1.5178E7 -2780000.0 -0.19 -0.1866 -1.0 3131060 CMLD2_000462 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H13 compound treatment 1.25527E7 -5400000.0 -0.36 -0.3629 -1.0 3131061 CMLD2_000463 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H14 compound treatment 9211940.0 -8740000.0 -0.59 -0.5872 -1.0 3011102 CMLD2_000464 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H15 compound treatment 1.92156E7 1260000.0 0.08 0.0846 1.0 3131062 CMLD2_000465 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC[C@@H](O)COCc6ccco6)n3c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H16 compound treatment 1.48481E7 -3110000.0 -0.21 -0.2087 -1.0 3011103 CMLD2_000466 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5ccc(F)cc5F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H17 compound treatment 1.60632E7 -1890000.0 -0.13 -0.1271 -1.0 3131063 CMLD2_000467 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H18 compound treatment 3.65556E7 1.86E7 1.25 1.2491 1.0 3011104 CMLD2_000468 CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H19 mock treatment 1.93226E7 1370000.0 0.09 0.0918 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H20 mock treatment 1.73312E7 -625000.0 -0.04 -0.042 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H21 compound treatment 2.24304E7 4470000.0 0.3 0.3005 1.0 3131064 CMLD2_000469 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H22 compound treatment 1.35363E7 -4420000.0 -0.3 -0.2968 -1.0 3011105 CMLD2_000470 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H23 compound treatment 7994510.0 -9960000.0 -0.67 -0.669 -1.0 3131065 CMLD2_000471 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 H24 compound treatment 0.0 -1.8E7 -1.21 -1.2058 -1.0 3131066 CMLD2_000472 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I01 compound treatment 2.19311E7 3980000.0 0.27 0.2669 1.0 3011106 CMLD2_000473 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I02 compound treatment 7630210.0 -1.03E7 -0.69 -0.6934 -1.0 3131067 CMLD2_000474 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I03 compound treatment 2.63472E7 8390000.0 0.56 0.5635 1.0 3131183 CMLD2_000475 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I04 compound treatment 1.60281E7 -1930000.0 -0.13 -0.1295 -1.0 3011108 CMLD2_000476 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I05 mock treatment 1.52231E7 -2730000.0 -0.18 -0.1835 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I06 mock treatment 7755330.0 -1.02E7 -0.69 -0.685 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I07 compound treatment 2.86612E7 1.07E7 0.72 0.7189 1.0 3131184 CMLD2_000477 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I08 compound treatment 8665680.0 -9290000.0 -0.62 -0.6239 -1.0 3011109 CMLD2_000478 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I09 compound treatment 2.48334E7 6880000.0 0.46 0.4619 1.0 3131185 CMLD2_000479 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I10 compound treatment 1.72354E7 -721000.0 -0.05 -0.0484 -1.0 3131186 CMLD2_000480 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I11 compound treatment 1.41939E7 -3760000.0 -0.25 -0.2526 -1.0 3011110 CMLD2_000481 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I12 compound treatment 3743280.0 -1.42E7 -0.95 -0.9545 -1.0 3131187 CMLD2_000482 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I13 compound treatment 1.03908E7 -7570000.0 -0.51 -0.508 -1.0 3131188 CMLD2_000483 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I14 compound treatment 1.50876E7 -2870000.0 -0.19 -0.1926 -1.0 3011112 CMLD2_000484 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I15 compound treatment 2.34203E7 5460000.0 0.37 0.367 1.0 3131189 CMLD2_000485 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCc5ccccc5)n2c1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I16 compound treatment 3.59141E8 3.41E8 22.91 22.9125 1.0 3011154 CMLD2_000486 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I17 compound treatment 2.02297E7 2270000.0 0.15 0.1527 1.0 3131190 CMLD2_000487 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I18 compound treatment 1.64779E7 -1480000.0 -0.1 -0.0993 -1.0 3010995 CMLD2_000488 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I19 compound treatment 5292140.0 -1.27E7 -0.85 -0.8505 -1.0 3131191 CMLD2_000489 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I20 compound treatment 7227490.0 -1.07E7 -0.72 -0.7205 -1.0 3131192 CMLD2_000490 C[C@H]/1COC(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I21 mock treatment 1.6615E7 -1340000.0 -0.09 -0.0901 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I22 mock treatment 1.30812E7 -4870000.0 -0.33 -0.3274 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I23 compound treatment 2.1668E7 3710000.0 0.25 0.2493 1.0 3131193 CMLD2_000491 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 I24 compound treatment 1.6459E7 -1500000.0 -0.1 -0.1005 -1.0 3011157 CMLD2_000492 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J01 compound treatment 1.70044E7 -952000.0 -0.06 -0.0639 -1.0 3131194 CMLD2_000493 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J02 compound treatment 2.11073E7 3150000.0 0.21 0.2116 1.0 3011158 CMLD2_000494 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J03 compound treatment 1.70207E7 -935000.0 -0.06 -0.0628 -1.0 3131195 CMLD2_000495 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J04 compound treatment 2.19939E7 4040000.0 0.27 0.2712 1.0 3011159 CMLD2_000496 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J05 mock treatment 2.28682E7 4910000.0 0.33 0.3299 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J06 mock treatment 1.99995E7 2040000.0 0.14 0.1372 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J07 compound treatment 1.55055E7 -2450000.0 -0.16 -0.1646 -1.0 3131196 CMLD2_000497 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J08 compound treatment 1.36239E7 -4330000.0 -0.29 -0.2909 -1.0 3131197 CMLD2_000498 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J09 compound treatment 2.37933E7 5840000.0 0.39 0.392 1.0 3011160 CMLD2_000499 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J10 compound treatment 1.65565E7 -1400000.0 -0.09 -0.094 -1.0 3131198 CMLD2_000500 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J11 compound treatment 3.20764E7 1.41E7 0.95 0.9483 1.0 3011161 CMLD2_000501 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J12 compound treatment 1.18571E7 -6100000.0 -0.41 -0.4096 -1.0 3131199 CMLD2_000502 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J13 compound treatment 1.8979E7 1020000.0 0.07 0.0687 1.0 3131200 CMLD2_000503 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J14 compound treatment 2.53631E7 7410000.0 0.5 0.4974 1.0 3011162 CMLD2_000504 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J15 compound treatment 2.666E7 8700000.0 0.58 0.5845 1.0 3131201 CMLD2_000505 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J16 compound treatment 2.0561E7 2600000.0 0.17 0.1749 1.0 3011163 CMLD2_000506 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J17 compound treatment 3471500.0 -1.45E7 -0.97 -0.9727 -1.0 3131202 CMLD2_000507 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J18 compound treatment 2.09962E7 3040000.0 0.2 0.2042 1.0 3011164 CMLD2_000508 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J19 compound treatment 1.94497E7 1490000.0 0.1 0.1003 1.0 3131320 CMLD2_000509 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J20 compound treatment 1.07868E7 -7170000.0 -0.48 -0.4815 -1.0 3131321 CMLD2_000510 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J21 mock treatment 2.04949E7 2540000.0 0.17 0.1705 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J22 mock treatment 1.907E7 1110000.0 0.07 0.0748 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J23 compound treatment 1.69435E7 -1010000.0 -0.07 -0.068 -1.0 1952481 CMLD2_000511 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 J24 compound treatment 1.36274E7 -4330000.0 -0.29 -0.2907 -1.0 3131322 CMLD2_000512 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K01 compound treatment 5016260.0 -1.29E7 -0.87 -0.869 -1.0 3131323 CMLD2_000513 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K02 compound treatment 8923970.0 -9030000.0 -0.61 -0.6066 -1.0 3011055 CMLD2_000514 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K03 compound treatment 3.07507E7 1.28E7 0.86 0.8592 1.0 3131324 CMLD2_000515 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K04 compound treatment 7788820.0 -1.02E7 -0.68 -0.6828 -1.0 3011057 CMLD2_000516 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K05 compound treatment 2.73644E7 9410000.0 0.63 0.6318 1.0 3131325 CMLD2_000517 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K06 compound treatment 2.96524E7 1.17E7 0.79 0.7855 1.0 3131326 CMLD2_000518 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K07 mock treatment 1.59288E7 -2030000.0 -0.14 -0.1361 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K08 mock treatment 1.57149E7 -2240000.0 -0.15 -0.1505 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K09 compound treatment 1.41526E7 -3800000.0 -0.26 -0.2554 -1.0 3011058 CMLD2_000519 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K10 compound treatment 2.99975E7 1.2E7 0.81 0.8087 1.0 3131327 CMLD2_000520 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K11 compound treatment 1.04149E7 -7540000.0 -0.51 -0.5064 -1.0 3011059 CMLD2_000521 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K12 compound treatment 1.10229E7 -6930000.0 -0.47 -0.4656 -1.0 3131328 CMLD2_000522 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K13 compound treatment 7521020.0 -1.04E7 -0.7 -0.7008 -1.0 3131329 CMLD2_000523 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K14 compound treatment 1.04112E7 -7540000.0 -0.51 -0.5067 -1.0 3011060 CMLD2_000524 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(c6ccccc6)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K15 mock treatment 2.07871E7 2830000.0 0.19 0.1901 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K16 mock treatment 1.79829E7 26900.0 0.0 0.0018 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K17 compound treatment 9823340.0 -8130000.0 -0.55 -0.5462 -1.0 3131330 CMLD2_000525 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K18 compound treatment 2.62342E7 8280000.0 0.56 0.5559 1.0 3011061 CMLD2_000526 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K19 compound treatment 2.15407E7 3580000.0 0.24 0.2407 1.0 3131331 CMLD2_000527 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K20 compound treatment 1.28914E7 -5060000.0 -0.34 -0.3401 -1.0 3011062 CMLD2_000528 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K21 compound treatment 1.34524E7 -4500000.0 -0.3 -0.3024 -1.0 3011070 CMLD2_000529 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K22 compound treatment 1.54479E7 -2510000.0 -0.17 -0.1684 -1.0 3011072 CMLD2_000530 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)COC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K23 mock treatment 8838160.0 -9120000.0 -0.61 -0.6123 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 K24 mock treatment 1.70656E7 -890000.0 -0.06 -0.0598 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L01 compound treatment 1.06341E7 -7320000.0 -0.49 -0.4917 -1.0 3131332 CMLD2_000531 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L02 compound treatment 1.82636E7 308000.0 0.02 0.0207 1.0 3131333 CMLD2_000532 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L03 compound treatment 1.91027E7 1150000.0 0.08 0.077 1.0 3011074 CMLD2_000533 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L04 compound treatment 2.02335E7 2280000.0 0.15 0.1529 1.0 3131334 CMLD2_000534 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L05 compound treatment 2.21838E7 4230000.0 0.28 0.2839 1.0 3131335 CMLD2_000535 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L06 compound treatment 2.80746E7 1.01E7 0.68 0.6795 1.0 3011078 CMLD2_000536 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L07 mock treatment 3.3022E7 1.51E7 1.01 1.0118 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L08 mock treatment 9249540.0 -8710000.0 -0.58 -0.5847 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L09 compound treatment 2.62366E7 8280000.0 0.56 0.5561 1.0 3011128 CMLD2_000537 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L10 compound treatment 2.90623E7 1.11E7 0.75 0.7458 1.0 3131336 CMLD2_000538 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L11 compound treatment 1.93255E7 1370000.0 0.09 0.092 1.0 3011131 CMLD2_000539 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L12 compound treatment 1.70719E7 -884000.0 -0.06 -0.0594 -1.0 3131337 CMLD2_000540 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L13 compound treatment 2.16704E7 3710000.0 0.25 0.2494 1.0 3131338 CMLD2_000541 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L14 compound treatment 2.33046E7 5350000.0 0.36 0.3592 1.0 3011134 CMLD2_000542 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L15 mock treatment 1.5508E7 -2450000.0 -0.16 -0.1644 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L16 mock treatment 3.1488E7 1.35E7 0.91 0.9087 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L17 compound treatment 1.41492E7 -3810000.0 -0.26 -0.2556 -1.0 3131454 CMLD2_000543 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L18 compound treatment 1.67456E7 -1210000.0 -0.08 -0.0813 -1.0 3011136 CMLD2_000544 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]4[C@H]([C@H](O)[C@@H]5O[C@@H]5C4=O)n3c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L19 compound treatment 3.69197E7 1.9E7 1.27 1.2735 1.0 3131455 CMLD2_000545 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L20 compound treatment 2.32323E7 5280000.0 0.35 0.3543 1.0 3131456 CMLD2_000546 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2)NS(=O)(=O)c3ccc(C)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L21 compound treatment 1.12503E7 -6710000.0 -0.45 -0.4503 -1.0 3011138 CMLD2_000547 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L22 compound treatment 2.78664E7 9910000.0 0.67 0.6655 1.0 3131457 CMLD2_000548 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L23 mock treatment 9594640.0 -8360000.0 -0.56 -0.5615 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 L24 mock treatment 8423820.0 -9530000.0 -0.64 -0.6401 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M01 compound treatment 7926930.0 -1.0E7 -0.67 -0.6735 -1.0 3011140 CMLD2_000549 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M02 compound treatment 1.04641E7 -7490000.0 -0.5 -0.5031 -1.0 3131458 CMLD2_000550 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M03 compound treatment 9534270.0 -8420000.0 -0.57 -0.5656 -1.0 3131459 CMLD2_000551 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M04 compound treatment 2.29973E7 5040000.0 0.34 0.3385 1.0 3011143 CMLD2_000552 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M05 compound treatment 1.01748E7 -7780000.0 -0.52 -0.5226 -1.0 3011168 CMLD2_000553 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M06 compound treatment 2.34419E7 5490000.0 0.37 0.3684 1.0 3131460 CMLD2_000554 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M07 compound treatment 1.23483E7 -5610000.0 -0.38 -0.3766 -1.0 3011171 CMLD2_000555 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M08 compound treatment 1.44348E7 -3520000.0 -0.24 -0.2365 -1.0 3131461 CMLD2_000556 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M09 mock treatment 2.21725E7 4220000.0 0.28 0.2832 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M10 mock treatment 2.27812E7 4830000.0 0.32 0.324 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M11 compound treatment 1.92379E7 1280000.0 0.09 0.0861 1.0 3011173 CMLD2_000557 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M12 compound treatment 1.93789E7 1420000.0 0.1 0.0956 1.0 3131462 CMLD2_000558 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(CC)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M13 mock treatment 1.39893E7 -3970000.0 -0.27 -0.2664 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M14 mock treatment 2.30927E7 5140000.0 0.34 0.345 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M15 compound treatment 3.58295E7 1.79E7 1.2 1.2003 1.0 3131463 CMLD2_000559 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M16 compound treatment 3.68264E8 3.5E8 23.53 23.5251 1.0 3011176 CMLD2_000560 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C[C@@H]5CCCO5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M17 compound treatment 8101100.0 -9850000.0 -0.66 -0.6618 -1.0 3131464 CMLD2_000561 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M18 compound treatment 2.50781E7 7120000.0 0.48 0.4783 1.0 3011178 CMLD2_000562 Cn1c(=O)n2CC[C@H]3[C@H]([C@H](O)[C@@H]4O[C@@H]4C3=O)n2c1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M19 compound treatment 2.31718E7 5220000.0 0.35 0.3503 1.0 3131465 CMLD2_000563 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M20 compound treatment 8542420.0 -9410000.0 -0.63 -0.6322 -1.0 3011181 CMLD2_000564 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M21 compound treatment 2.18756E7 3920000.0 0.26 0.2632 1.0 3131466 CMLD2_000565 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M22 compound treatment 1.97232E7 1770000.0 0.12 0.1187 1.0 3011183 CMLD2_000566 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M23 compound treatment 8954240.0 -9000000.0 -0.6 -0.6045 -1.0 3131467 CMLD2_000567 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 M24 compound treatment 1.79152E7 -40800.0 0.0 -0.0027 -1.0 3131468 CMLD2_000568 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N01 compound treatment 7469410.0 -1.05E7 -0.7 -0.7042 -1.0 3131469 CMLD2_000569 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N02 compound treatment 1.74315E7 -525000.0 -0.04 -0.0352 -1.0 3011201 CMLD2_000570 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N03 compound treatment 1.60158E7 -1940000.0 -0.13 -0.1303 -1.0 3131470 CMLD2_000571 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N04 compound treatment 3.45983E7 1.66E7 1.12 1.1176 1.0 3131471 CMLD2_000572 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N05 compound treatment 2.36617E7 5710000.0 0.38 0.3832 1.0 3011203 CMLD2_000573 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N06 compound treatment 5609280.0 -1.23E7 -0.83 -0.8292 -1.0 3131472 CMLD2_000574 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N07 compound treatment 1.48568E7 -3100000.0 -0.21 -0.2081 -1.0 3011205 CMLD2_000575 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N08 compound treatment 5.77218E7 3.98E7 2.67 2.6705 1.0 3131588 CMLD2_000576 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N09 mock treatment 1.85125E7 556000.0 0.04 0.0374 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N10 mock treatment 3.23398E7 1.44E7 0.97 0.966 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N11 compound treatment 1.62731E7 -1680000.0 -0.11 -0.113 -1.0 3011207 CMLD2_000577 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N12 compound treatment 9929330.0 -8030000.0 -0.54 -0.539 -1.0 3131589 CMLD2_000578 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N13 mock treatment 3.20748E7 1.41E7 0.95 0.9482 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N14 mock treatment 1.35354E7 -4420000.0 -0.3 -0.2969 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N15 compound treatment 2.51574E7 7200000.0 0.48 0.4836 1.0 3131590 CMLD2_000579 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCCCC#C)n2c1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N16 compound treatment 2.55121E8 2.37E8 15.93 15.9269 1.0 3011210 CMLD2_000580 C[C@@H](N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N17 compound treatment 5.16832E7 3.37E7 2.26 2.265 1.0 3131591 CMLD2_000581 C[C@H](N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N18 compound treatment 9267020.0 -8690000.0 -0.58 -0.5835 -1.0 3011211 CMLD2_000582 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N19 compound treatment 1.69913E7 -965000.0 -0.06 -0.0648 -1.0 3131592 CMLD2_000583 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N20 compound treatment 1.71428E7 -813000.0 -0.05 -0.0546 -1.0 3131593 CMLD2_000584 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N21 compound treatment 2.86857E7 1.07E7 0.72 0.7206 1.0 3011214 CMLD2_000585 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@H](C)C(=O)OC[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N22 compound treatment 3.25264E7 1.46E7 0.98 0.9785 1.0 3011226 CMLD2_000586 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N23 compound treatment 1.41341E7 -3820000.0 -0.26 -0.2567 -1.0 3131594 CMLD2_000587 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]3CCCN3C(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 N24 compound treatment 1.20279E7 -5930000.0 -0.4 -0.3981 -1.0 3131054 CMLD2_000588 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O01 compound treatment 2.09378E7 2980000.0 0.2 0.2002 1.0 3131595 CMLD2_000589 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O02 compound treatment 1.01875E7 -7770000.0 -0.52 -0.5217 -1.0 3011229 CMLD2_000590 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O03 compound treatment 1.3737E7 -4220000.0 -0.28 -0.2833 -1.0 3131596 CMLD2_000591 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O04 compound treatment 4.28994E7 2.49E7 1.68 1.6751 1.0 3011196 CMLD2_000592 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O05 compound treatment 1.8589E7 633000.0 0.04 0.0425 1.0 3131597 CMLD2_000593 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O06 compound treatment 1.86088E7 653000.0 0.04 0.0438 1.0 3131598 CMLD2_000594 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O07 compound treatment 2.46222E7 6670000.0 0.45 0.4477 1.0 3011231 CMLD2_000595 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O08 compound treatment 2.15012E7 3550000.0 0.24 0.2381 1.0 3131599 CMLD2_000596 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O09 compound treatment 1.36825E7 -4270000.0 -0.29 -0.287 -1.0 3011237 CMLD2_000597 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O10 compound treatment 2.67129E7 8760000.0 0.59 0.5881 1.0 3131600 CMLD2_000598 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O11 mock treatment 3.75256E7 1.96E7 1.31 1.3142 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O12 mock treatment 1.46686E7 -3290000.0 -0.22 -0.2208 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O13 compound treatment 3.20781E7 1.41E7 0.95 0.9484 1.0 3011239 CMLD2_000599 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O14 compound treatment 5848060.0 -1.21E7 -0.81 -0.8131 -1.0 3131601 CMLD2_000600 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O15 compound treatment 1.65696E7 -1390000.0 -0.09 -0.0931 -1.0 3131602 CMLD2_000601 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OC[C@@H](O)COCc5ccco5)n2c1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O16 compound treatment 5.07549E8 4.9E8 32.88 32.8789 1.0 3012175 CMLD2_000602 CCOC(=O)CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O17 compound treatment 2.49356E7 6980000.0 0.47 0.4687 1.0 3012176 CMLD2_000603 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O18 compound treatment 2.3569E7 5610000.0 0.38 0.3769 1.0 3012177 CMLD2_000604 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O19 compound treatment 1.53923E7 -2560000.0 -0.17 -0.1722 -1.0 3012178 CMLD2_000605 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O20 compound treatment 1.78588E7 -97200.0 -0.01 -0.0065 -1.0 3012179 CMLD2_000606 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O21 compound treatment 9729940.0 -8230000.0 -0.55 -0.5524 -1.0 3131603 CMLD2_000607 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@@H](C)C(=O)OC[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O22 compound treatment 6379040.0 -1.16E7 -0.78 -0.7775 -1.0 3011105 CMLD2_000608 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O23 compound treatment 8934690.0 -9020000.0 -0.61 -0.6058 -1.0 3012180 CMLD2_000609 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 O24 compound treatment 1.9776E7 1820000.0 0.12 0.1222 1.0 3131604 CMLD2_000610 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P01 compound treatment 1.09477E7 -7010000.0 -0.47 -0.4706 -1.0 3131605 CMLD2_000611 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P02 compound treatment 1.47635E7 -3190000.0 -0.21 -0.2144 -1.0 3012181 CMLD2_000612 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P03 compound treatment 1.47406E7 -3220000.0 -0.22 -0.2159 -1.0 3131606 CMLD2_000613 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P04 compound treatment 3.14428E7 1.35E7 0.91 0.9057 1.0 3012182 CMLD2_000614 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P05 compound treatment 1.053E7 -7430000.0 -0.5 -0.4987 -1.0 3131723 CMLD2_000615 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P06 compound treatment 1.51308E7 -2830000.0 -0.19 -0.1897 -1.0 3131724 CMLD2_000616 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P07 compound treatment 1.17454E7 -6210000.0 -0.42 -0.4171 -1.0 3012183 CMLD2_000617 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P08 compound treatment 1.46628E7 -3290000.0 -0.22 -0.2212 -1.0 3131725 CMLD2_000618 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P09 compound treatment 1.43041E7 -3650000.0 -0.25 -0.2452 -1.0 3012184 CMLD2_000619 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P10 compound treatment 2.07831E7 2830000.0 0.19 0.1899 1.0 3131726 CMLD2_000620 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P11 mock treatment 9599100.0 -8360000.0 -0.56 -0.5612 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P12 mock treatment 1.74266E7 -529000.0 -0.04 -0.0356 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P13 compound treatment 1.24532E7 -5500000.0 -0.37 -0.3695 -1.0 3131727 CMLD2_000621 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P14 compound treatment 7469600.0 -1.05E7 -0.7 -0.7042 -1.0 3012185 CMLD2_000622 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P15 compound treatment 2.50635E7 7110000.0 0.48 0.4773 1.0 3131728 CMLD2_000623 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P16 compound treatment 1.40865E8 1.23E8 8.25 8.254 1.0 3012186 CMLD2_000624 CC(C)(C)N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P17 compound treatment 1.31699E7 -4790000.0 -0.32 -0.3214 -1.0 3131729 CMLD2_000625 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P18 compound treatment 2.30021E7 5050000.0 0.34 0.3389 1.0 3012187 CMLD2_000626 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4ccc(F)cc4F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P19 compound treatment 1.11937E7 -6760000.0 -0.45 -0.4541 -1.0 3131730 CMLD2_000627 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@H](O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P20 compound treatment 1.94249E7 1470000.0 0.1 0.0986 1.0 3012188 CMLD2_000628 C[C@H]/1COC(=O)C\C=C\[C@@H](C)[C@H]2O[C@H](COC(=O)C\C=C1)[C@@H](O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P21 compound treatment 1.5124E7 -2830000.0 -0.19 -0.1902 -1.0 3131731 CMLD2_000629 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P22 compound treatment 2.22767E7 4320000.0 0.29 0.2902 1.0 3012189 CMLD2_000630 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)COC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P23 compound treatment 1.26313E7 -5320000.0 -0.36 -0.3576 -1.0 3131732 CMLD2_000631 CO[C@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](OCc3ccccc3)/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2110 P24 compound treatment 8215630.0 -9740000.0 -0.65 -0.6541 -1.0 3131733 CMLD2_000632 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A01 compound treatment 2.05637E7 3610000.0 0.24 0.2427 1.0 3012190 CMLD2_000633 CO[C@@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A02 compound treatment 1.14413E7 -5510000.0 -0.37 -0.3699 -1.0 3131321 CMLD2_000634 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A03 compound treatment 7569230.0 -9380000.0 -0.63 -0.6299 -1.0 3131734 CMLD2_000635 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A04 compound treatment 7354450.0 -9590000.0 -0.64 -0.6444 -1.0 3131735 CMLD2_000636 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A05 compound treatment 2.51121E7 8160000.0 0.55 0.5482 1.0 3012191 CMLD2_000637 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A06 compound treatment 2.59594E7 9010000.0 0.61 0.6051 1.0 3131736 CMLD2_000638 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A07 compound treatment 2.67892E7 9840000.0 0.66 0.6608 1.0 3012192 CMLD2_000639 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A08 compound treatment 1.79909E7 1040000.0 0.07 0.0699 1.0 3131737 CMLD2_000640 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A09 compound treatment 1.15643E7 -5390000.0 -0.36 -0.3616 -1.0 3131738 CMLD2_000641 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)cc2)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A10 compound treatment 1.56463E7 -1300000.0 -0.09 -0.0875 -1.0 3012193 CMLD2_000642 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A11 compound treatment 2.06335E7 3680000.0 0.25 0.2474 1.0 3131739 CMLD2_000643 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A12 compound treatment 2.66647E7 9720000.0 0.65 0.6524 1.0 3012194 CMLD2_000644 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A13 mock treatment 6404610.0 -1.05E7 -0.71 -0.7081 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A14 mock treatment 1.64528E7 -497000.0 -0.03 -0.0333 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A15 compound treatment 1.30976E7 -3850000.0 -0.26 -0.2587 -1.0 3131740 CMLD2_000645 CCc1cc2CN(CC/C(=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A16 compound treatment 9422660.0 -7530000.0 -0.51 -0.5055 -1.0 3131741 CMLD2_000646 CCc1cc2CN(CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A17 compound treatment 2.21944E7 5250000.0 0.35 0.3522 1.0 3012195 CMLD2_000647 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cc(no5)c6c(C)cc(C)cc6C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A18 compound treatment 8012060.0 -8940000.0 -0.6 -0.6002 -1.0 3131860 CMLD2_000648 CO[C@H](/C=N/O[C@@H](C)c1cc(no1)c2c(C)cc(C)cc2C)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A19 compound treatment 6673840.0 -1.03E7 -0.69 -0.6901 -1.0 3012196 CMLD2_000649 C[C@H](ON=C(C)C)c1cc(no1)c2c(C)cc(C)cc2C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A20 compound treatment 2.56698E7 8720000.0 0.59 0.5856 1.0 3131861 CMLD2_000650 CO/N=C/[C@@H](C)[C@H](OCc1ccccc1)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A21 compound treatment 3.24592E7 1.55E7 1.04 1.0416 1.0 3131714 CMLD2_000651 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A22 compound treatment 2.47836E7 7830000.0 0.53 0.5261 1.0 3012197 CMLD2_000652 C[C@@H]1CC[C@@H]2N(C[C@@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A23 mock treatment 1.24805E7 -4470000.0 -0.3 -0.3001 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 A24 mock treatment 1.21674E7 -4780000.0 -0.32 -0.3211 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B01 compound treatment 2.92552E7 1.23E7 0.83 0.8264 1.0 3131862 CMLD2_000653 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B02 compound treatment 5729620.0 -1.12E7 -0.75 -0.7535 -1.0 3011062 CMLD2_000654 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B03 compound treatment 1.12836E7 -5670000.0 -0.38 -0.3805 -1.0 3131863 CMLD2_000655 CO[C@@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B04 compound treatment 9299500.0 -7650000.0 -0.51 -0.5137 -1.0 3012198 CMLD2_000656 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B05 compound treatment 1.51451E7 -1800000.0 -0.12 -0.1212 -1.0 3131864 CMLD2_000657 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cc(no4)c5c(C)cc(C)cc5C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B06 compound treatment 1.50166E7 -1930000.0 -0.13 -0.1298 -1.0 3131865 CMLD2_000658 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cc(no2)c3c(C)cc(C)cc3C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B07 compound treatment 9828610.0 -7120000.0 -0.48 -0.4782 -1.0 3012199 CMLD2_000659 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B08 compound treatment 7124340.0 -9830000.0 -0.66 -0.6598 -1.0 3131866 CMLD2_000660 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B09 compound treatment 1.06821E7 -6270000.0 -0.42 -0.4209 -1.0 3131867 CMLD2_000661 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B10 compound treatment 8982530.0 -7970000.0 -0.54 -0.535 -1.0 3012228 CMLD2_000662 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B11 compound treatment 1.16154E7 -5330000.0 -0.36 -0.3582 -1.0 3131868 CMLD2_000663 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B12 compound treatment 2.7955E7 1.1E7 0.74 0.7391 1.0 3130911 CMLD2_000664 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B13 mock treatment 7864220.0 -9090000.0 -0.61 -0.6101 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B14 mock treatment 1.27735E7 -4180000.0 -0.28 -0.2804 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B15 compound treatment 1.02493E7 -6700000.0 -0.45 -0.4499 -1.0 3131869 CMLD2_000665 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(CC)c(CC)cc3C2)C=C[C@@H]1Oc4ccc(OC)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B16 compound treatment 1.77455E7 796000.0 0.05 0.0535 1.0 3012230 CMLD2_000666 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B17 compound treatment 6399540.0 -1.05E7 -0.71 -0.7085 -1.0 3131870 CMLD2_000667 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B18 compound treatment 1.33638E7 -3590000.0 -0.24 -0.2408 -1.0 3012231 CMLD2_000668 CO[C@H](/C=N/OC[C@@H](C)[C@H](OCc1ccccc1)C(C)C)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B19 compound treatment 1.85173E7 1570000.0 0.11 0.1053 1.0 3131871 CMLD2_000669 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CON=C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B20 compound treatment 2011900.0 -1.49E7 -1.0 -1.0031 -1.0 3012232 CMLD2_000670 CCc1cc2CN(CC/C(=N/OC)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B21 compound treatment 3585230.0 -1.34E7 -0.9 -0.8975 -1.0 3131872 CMLD2_000671 C[C@@H]1CC[C@@H]2N(C[C@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B22 compound treatment 1.89944E7 2050000.0 0.14 0.1373 1.0 3131873 CMLD2_000672 COc1ccc(OC[C@H]2CN3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B23 mock treatment 1.83938E7 1440000.0 0.1 0.097 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 B24 mock treatment 2.47302E7 7780000.0 0.52 0.5225 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C01 compound treatment 1.64264E7 -523000.0 -0.04 -0.0351 -1.0 3012233 CMLD2_000673 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C02 compound treatment 9292900.0 -7660000.0 -0.51 -0.5142 -1.0 3011181 CMLD2_000674 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C03 compound treatment 1.43646E7 -2580000.0 -0.17 -0.1736 -1.0 3131874 CMLD2_000675 CO[C@@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C04 compound treatment 2.20466E7 5100000.0 0.34 0.3423 1.0 3131875 CMLD2_000676 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C05 compound treatment 1.96809E7 2730000.0 0.18 0.1834 1.0 3012234 CMLD2_000677 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C06 compound treatment 2.54101E7 8460000.0 0.57 0.5682 1.0 3131876 CMLD2_000678 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C07 compound treatment 2.48351E7 7890000.0 0.53 0.5296 1.0 3131877 CMLD2_000679 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C08 compound treatment 4.57092E7 2.88E7 1.93 1.9314 1.0 3012270 CMLD2_000680 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)cc2)c6ccc(C)cc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C09 compound treatment 1.07864E7 -6160000.0 -0.41 -0.4139 -1.0 3131878 CMLD2_000681 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C10 compound treatment 1.62559E7 -693000.0 -0.05 -0.0466 -1.0 3131879 CMLD2_000682 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C11 mock treatment 2.11672E7 4220000.0 0.28 0.2833 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C12 mock treatment 3887570.0 -1.31E7 -0.88 -0.8772 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C13 compound treatment 9314050.0 -7640000.0 -0.51 -0.5128 -1.0 3012273 CMLD2_000683 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C14 compound treatment 2.39762E7 7030000.0 0.47 0.4719 1.0 3131994 CMLD2_000684 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C15 mock treatment 1.53489E7 -1600000.0 -0.11 -0.1075 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C16 mock treatment 2.09311E7 3980000.0 0.27 0.2674 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C17 compound treatment 1.59494E7 -1000000.0 -0.07 -0.0672 -1.0 3131995 CMLD2_000685 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C18 compound treatment 9755360.0 -7190000.0 -0.48 -0.4831 -1.0 3012274 CMLD2_000686 CO[C@H](/C=N/O[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C19 compound treatment 2.20426E7 5090000.0 0.34 0.342 1.0 3012275 CMLD2_000687 CC(=NO[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C20 compound treatment 2.44122E7 7460000.0 0.5 0.5012 1.0 3131996 CMLD2_000688 CO/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C21 compound treatment 2.29246E7 5980000.0 0.4 0.4013 1.0 3011349 CMLD2_000689 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C22 compound treatment 3.19585E7 1.5E7 1.01 1.0079 1.0 3131997 CMLD2_000690 COc1ccc(OC[C@@H]2CC3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C23 mock treatment 1.97032E7 2750000.0 0.18 0.1849 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 C24 mock treatment 9817100.0 -7130000.0 -0.48 -0.479 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D01 compound treatment 2.23353E7 5390000.0 0.36 0.3617 1.0 3012277 CMLD2_000691 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D02 compound treatment 3791490.0 -1.32E7 -0.88 -0.8836 -1.0 3131998 CMLD2_000692 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](CCSC)NC(=O)C\C=C\[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D03 compound treatment 9186820.0 -7760000.0 -0.52 -0.5213 -1.0 3012278 CMLD2_000693 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)CCC[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D04 compound treatment 2.43932E7 7440000.0 0.5 0.4999 1.0 3131999 CMLD2_000694 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D05 compound treatment 1.07405E7 -6210000.0 -0.42 -0.417 -1.0 3132000 CMLD2_000695 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D06 compound treatment 2.04512E7 3500000.0 0.24 0.2352 1.0 3012279 CMLD2_000696 CC(=O)OC[C@H]1O[C@H](C/C=N/OC2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D07 compound treatment 2.89367E7 1.2E7 0.81 0.805 1.0 3132001 CMLD2_000697 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1Oc4ccc(OC)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D08 compound treatment 2.05017E7 3550000.0 0.24 0.2386 1.0 3132002 CMLD2_000698 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/c2ccc(cc2)C(=O)N3[C@@H](CC[C@H](C)[C@H]3c4ccc(C)cc4)C(=O)OC)C=C[C@@H]1Oc5ccc(OC)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D09 compound treatment 1.87717E7 1820000.0 0.12 0.1224 1.0 3012280 CMLD2_000699 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc3ccc(OC)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D10 compound treatment 1.38783E7 -3070000.0 -0.21 -0.2062 -1.0 3132003 CMLD2_000700 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D11 mock treatment 1.64235E7 -526000.0 -0.04 -0.0353 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D12 mock treatment 2.74829E7 1.05E7 0.71 0.7074 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D13 compound treatment 1.10572E7 -5890000.0 -0.4 -0.3957 -1.0 3012281 CMLD2_000701 CC1(C)O[C@H]2O[C@H]([C@H](O)CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)[C@H](O)[C@H]2O1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D14 compound treatment 2.44008E7 7450000.0 0.5 0.5004 1.0 3132004 CMLD2_000702 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D15 mock treatment 1.60037E7 -946000.0 -0.06 -0.0635 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D16 mock treatment 1.30737E7 -3880000.0 -0.26 -0.2603 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D17 compound treatment 1.71657E7 216000.0 0.01 0.0145 1.0 3132005 CMLD2_000703 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D18 compound treatment 1.08427E7 -6110000.0 -0.41 -0.4101 -1.0 3012283 CMLD2_000704 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D19 compound treatment 2.44803E7 7530000.0 0.51 0.5057 1.0 3132006 CMLD2_000705 C[C@@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D20 compound treatment 1.10808E7 -5870000.0 -0.39 -0.3941 -1.0 3012284 CMLD2_000706 CO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D21 compound treatment 1.42257E7 -2720000.0 -0.18 -0.1829 -1.0 3132007 CMLD2_000707 CCCC[C@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D22 compound treatment 1.42575E7 -2690000.0 -0.18 -0.1808 -1.0 3132008 CMLD2_000708 C[C@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D23 mock treatment 1.70695E7 120000.0 0.01 0.0081 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 D24 mock treatment 2.03956E7 3450000.0 0.23 0.2314 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E01 mock treatment 2.14717E7 4520000.0 0.3 0.3037 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E02 mock treatment 2.75308E7 1.06E7 0.71 0.7106 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E03 compound treatment 2.66082E7 9660000.0 0.65 0.6486 1.0 3012286 CMLD2_000709 CO[C@@H]1COC(=O)CCC[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E04 compound treatment 3.01619E7 1.32E7 0.89 0.8873 1.0 3132009 CMLD2_000710 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E05 compound treatment 1.71931E7 244000.0 0.02 0.0164 1.0 3012287 CMLD2_000711 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E06 compound treatment 3.78205E7 2.09E7 1.4 1.4016 1.0 3132010 CMLD2_000712 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E07 compound treatment 6724860.0 -1.02E7 -0.69 -0.6866 -1.0 3012333 CMLD2_000713 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E08 compound treatment 2.06331E7 3680000.0 0.25 0.2474 1.0 3132011 CMLD2_000714 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)cc2)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E09 mock treatment 1.23388E7 -4610000.0 -0.31 -0.3096 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E10 mock treatment 2.14426E7 4490000.0 0.3 0.3017 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E11 compound treatment 2.08487E7 3900000.0 0.26 0.2619 1.0 3012334 CMLD2_000715 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E12 compound treatment 2.74546E7 1.05E7 0.71 0.7055 1.0 3132012 CMLD2_000716 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E13 compound treatment 1.20805E7 -4870000.0 -0.33 -0.327 -1.0 3012337 CMLD2_000717 OC[C@H]1O[C@H](CC=C)C=C[C@@H]1O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E14 compound treatment 5055230.0 -1.19E7 -0.8 -0.7988 -1.0 3132130 CMLD2_000718 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E15 compound treatment 1.96291E7 2680000.0 0.18 0.18 1.0 3132131 CMLD2_000719 CCc1cc2CN(CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E16 compound treatment 2.62222E7 9270000.0 0.62 0.6227 1.0 3132132 CMLD2_000720 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6)c7ccccc7)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E17 mock treatment 2.26148E7 5670000.0 0.38 0.3805 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E18 mock treatment 1.43056E7 -2640000.0 -0.18 -0.1775 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E19 compound treatment 2.16343E7 4680000.0 0.31 0.3146 1.0 3012338 CMLD2_000721 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E20 mock treatment 2.13639E7 4410000.0 0.3 0.2965 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E21 compound treatment 1.41879E7 -2760000.0 -0.19 -0.1854 -1.0 3131584 CMLD2_000722 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E22 compound treatment 2.73505E7 1.04E7 0.7 0.6985 1.0 3012339 CMLD2_000723 COC(=O)C/C=C/[C@@H](C)[C@H](OCc1cccc(c1)c2ccccc2)C3CCCCC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E23 mock treatment 1.62887E7 -661000.0 -0.04 -0.0444 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 E24 mock treatment 1.94869E7 2540000.0 0.17 0.1704 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F01 mock treatment 1.51754E7 -1770000.0 -0.12 -0.1191 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F02 mock treatment 1.53599E7 -1590000.0 -0.11 -0.1067 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F03 compound treatment 1.65079E7 -441000.0 -0.03 -0.0296 -1.0 3132133 CMLD2_000724 C[C@H]1/C=C/CC(=O)OC[C@H](NS(=O)(=O)c2ccc(C)cc2)[C@@H](C)/C=C/CC(=O)OC[C@@H]1NS(=O)(=O)c3ccc(C)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F04 compound treatment 1.20391E7 -4910000.0 -0.33 -0.3298 -1.0 3012198 CMLD2_000725 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F05 compound treatment 2.48709E7 7920000.0 0.53 0.532 1.0 3132134 CMLD2_000726 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F06 compound treatment 2.40724E7 7120000.0 0.48 0.4784 1.0 3012341 CMLD2_000727 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F07 compound treatment 1.54438E7 -1510000.0 -0.1 -0.1011 -1.0 3132135 CMLD2_000728 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F08 compound treatment 1.69112E7 -38100.0 0.0 -0.0026 -1.0 3132136 CMLD2_000729 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)cc2)c5ccc(C)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F09 mock treatment 3236340.0 -1.37E7 -0.92 -0.9209 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F10 mock treatment 1.43832E7 -2570000.0 -0.17 -0.1723 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F11 compound treatment 2.4735E7 7790000.0 0.52 0.5228 1.0 3012342 CMLD2_000730 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F12 compound treatment 1.71743E7 225000.0 0.02 0.0151 1.0 3132137 CMLD2_000731 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F13 compound treatment 8629140.0 -8320000.0 -0.56 -0.5587 -1.0 3010880 CMLD2_000732 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F14 compound treatment 9263060.0 -7690000.0 -0.52 -0.5162 -1.0 3012343 CMLD2_000733 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F15 compound treatment 6680140.0 -1.03E7 -0.69 -0.6896 -1.0 3132138 CMLD2_000734 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F16 compound treatment 7985140.0 -8960000.0 -0.6 -0.602 -1.0 3132139 CMLD2_000735 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1Oc6ccc(OC)cc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F17 mock treatment 2.65259E7 9580000.0 0.64 0.6431 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F18 mock treatment 9282640.0 -7670000.0 -0.51 -0.5149 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F19 compound treatment 2.6234E7 9280000.0 0.62 0.6235 1.0 3012344 CMLD2_000736 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F20 mock treatment 8939020.0 -8010000.0 -0.54 -0.5379 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F21 compound treatment 8231310.0 -8720000.0 -0.59 -0.5855 -1.0 3012345 CMLD2_000737 C[C@@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F22 compound treatment 2.03874E7 3440000.0 0.23 0.2309 1.0 3132140 CMLD2_000738 CO[C@@H]([C@H](C)/C=C/CC(=O)OCCCc1ccccc1)C2CCCCC2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F23 mock treatment 1.72629E7 314000.0 0.02 0.0211 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 F24 mock treatment 6576370.0 -1.04E7 -0.7 -0.6966 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G01 compound treatment 2.71968E7 1.02E7 0.69 0.6882 1.0 3132141 CMLD2_000739 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G02 compound treatment 3.94121E7 2.25E7 1.51 1.5085 1.0 3012346 CMLD2_000740 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G03 mock treatment 1.68446E7 -105000.0 -0.01 -0.007 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G04 mock treatment 3.5337E7 1.84E7 1.23 1.2348 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G05 compound treatment 1.91526E7 2200000.0 0.15 0.148 1.0 3132142 CMLD2_000741 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1Oc3ccc(OC)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G06 compound treatment 2.4249E7 7300000.0 0.49 0.4902 1.0 3012347 CMLD2_000742 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G07 mock treatment 9.42508E7 7.73E7 5.19 5.1912 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G08 mock treatment 1.90018E7 2050000.0 0.14 0.1378 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G09 compound treatment 1.613E7 -819000.0 -0.06 -0.055 -1.0 3132143 CMLD2_000743 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G10 compound treatment 1.4622E7 -2330000.0 -0.16 -0.1563 -1.0 3132144 CMLD2_000744 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C\3/[C@H](O)[C@H](Oc4ccc(OC)cc34)c5cccc(OC)c5)c6ccccc6)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G11 compound treatment 1.54172E7 -1530000.0 -0.1 -0.1029 -1.0 3132145 CMLD2_000745 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G12 compound treatment 8976780.0 -7970000.0 -0.54 -0.5354 -1.0 3012401 CMLD2_000746 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G13 compound treatment 2.49927E7 8040000.0 0.54 0.5402 1.0 3132146 CMLD2_000747 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@@H]7COC[C@H]7O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G14 compound treatment 7800480.0 -9150000.0 -0.61 -0.6144 -1.0 3012403 CMLD2_000748 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G15 compound treatment 0.0 -1.69E7 -1.14 -1.1382 -1.0 3132147 CMLD2_000749 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G16 compound treatment 1.82635E7 1310000.0 0.09 0.0883 1.0 3012404 CMLD2_000750 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G17 compound treatment 2.23376E7 5390000.0 0.36 0.3619 1.0 3132148 CMLD2_000751 CO[C@H](/C=N/OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G18 compound treatment 6825040.0 -1.01E7 -0.68 -0.6799 -1.0 3132267 CMLD2_000752 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CON=C(C)C)c3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G19 mock treatment 2.40642E7 7110000.0 0.48 0.4778 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G20 mock treatment 8384210.0 -8570000.0 -0.58 -0.5752 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G21 compound treatment 3.16089E7 1.47E7 0.98 0.9845 1.0 3012405 CMLD2_000753 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G22 compound treatment 2.27891E7 5840000.0 0.39 0.3922 1.0 3132268 CMLD2_000754 CO[C@H]([C@@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)CO)C2CCCCC2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G23 mock treatment 2.30818E7 6130000.0 0.41 0.4118 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 G24 mock treatment 1949780.0 -1.5E7 -1.01 -1.0073 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H01 compound treatment 1.63292E7 -620000.0 -0.04 -0.0416 -1.0 3012408 CMLD2_000755 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H02 compound treatment 2.85734E7 1.16E7 0.78 0.7806 1.0 3132269 CMLD2_000756 C[C@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H03 mock treatment 2.49999E7 8050000.0 0.54 0.5406 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H04 mock treatment 1.28024E7 -4150000.0 -0.28 -0.2785 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H05 compound treatment 5853120.0 -1.11E7 -0.75 -0.7452 -1.0 3132270 CMLD2_000757 CC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H06 compound treatment 1.75876E7 638000.0 0.04 0.0429 1.0 3012411 CMLD2_000758 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCCCc4nc(C)c(C)cc34 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H07 mock treatment 1.48059E7 -2140000.0 -0.14 -0.1439 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H08 compound treatment 2.64487E7 9500000.0 0.64 0.6379 1.0 3132271 CMLD2_000759 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)cc2)c5ccc(C)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H09 compound treatment 2.29739E7 6020000.0 0.4 0.4046 1.0 3132272 CMLD2_000760 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H10 compound treatment 1.38711E7 -3080000.0 -0.21 -0.2067 -1.0 3012412 CMLD2_000761 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C\2/[C@H](O)[C@H](Oc3ccc(OC)cc23)c4cccc(OC)c4)C=C[C@@H]1Oc5ccc(OC)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H11 compound treatment 1.20222E7 -4930000.0 -0.33 -0.3309 -1.0 3132273 CMLD2_000762 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H12 compound treatment 4976540.0 -1.2E7 -0.8 -0.804 -1.0 3132274 CMLD2_000763 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H13 compound treatment 5558740.0 -1.14E7 -0.76 -0.7649 -1.0 3012414 CMLD2_000764 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H14 compound treatment 8532430.0 -8420000.0 -0.57 -0.5652 -1.0 3132275 CMLD2_000765 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)COCc2ccco2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H15 compound treatment 4151360.0 -1.28E7 -0.86 -0.8595 -1.0 3012415 CMLD2_000766 CCc1cc2CN(CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H16 compound treatment 0.0 -1.69E7 -1.14 -1.1382 -1.0 3132276 CMLD2_000767 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H17 compound treatment 9864930.0 -7080000.0 -0.48 -0.4758 -1.0 3132277 CMLD2_000768 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc2ccc(OC)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H18 compound treatment 1.38275E7 -3120000.0 -0.21 -0.2096 -1.0 3012416 CMLD2_000769 CCCNC(=O)OC[C@H]1O[C@H](CCON=C(C)C)C=C[C@@H]1Oc2ccc(OC)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H19 mock treatment 9332720.0 -7620000.0 -0.51 -0.5115 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H20 mock treatment 2.70812E7 1.01E7 0.68 0.6804 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H21 compound treatment 9560930.0 -7390000.0 -0.5 -0.4962 -1.0 3132278 CMLD2_000770 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H22 compound treatment 1.13415E7 -5610000.0 -0.38 -0.3766 -1.0 3012418 CMLD2_000771 CO[C@H]1[C@H](C)/C(=C\CCOCC#CC)/c2ccccc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H23 mock treatment 2.05326E7 3580000.0 0.24 0.2406 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 H24 mock treatment 9843970.0 -7110000.0 -0.48 -0.4772 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I01 compound treatment 1.28567E7 -4090000.0 -0.27 -0.2748 -1.0 3132279 CMLD2_000772 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I02 compound treatment 9485680.0 -7460000.0 -0.5 -0.5012 -1.0 3012419 CMLD2_000773 C[C@@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I03 compound treatment 1.00579E7 -6890000.0 -0.46 -0.4628 -1.0 3132280 CMLD2_000774 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)c6ccccc6)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I04 compound treatment 2.5356E7 8410000.0 0.56 0.5646 1.0 3132281 CMLD2_000775 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I05 mock treatment 1.90956E7 2150000.0 0.14 0.1441 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I06 mock treatment 9114030.0 -7840000.0 -0.53 -0.5262 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I07 compound treatment 1.39831E7 -2970000.0 -0.2 -0.1992 -1.0 3012420 CMLD2_000776 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I08 compound treatment 1.04415E7 -6510000.0 -0.44 -0.437 -1.0 3132282 CMLD2_000777 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)cc2)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I09 compound treatment 3.15958E7 1.46E7 0.98 0.9836 1.0 3012421 CMLD2_000778 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I10 compound treatment 1.95585E7 2610000.0 0.18 0.1752 1.0 3132283 CMLD2_000779 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I11 compound treatment 2.46504E7 7700000.0 0.52 0.5172 1.0 3012422 CMLD2_000780 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@H]4O[C@@H](C=C[C@@H]4Oc5ccc(OC)cc5)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I12 compound treatment 6.29963E7 4.6E7 3.09 3.0923 1.0 3012473 CMLD2_000781 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I13 compound treatment 4546130.0 -1.24E7 -0.83 -0.8329 -1.0 3132284 CMLD2_000782 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cc(no6)c7c(C)cc(C)cc7C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I14 compound treatment 3014500.0 -1.39E7 -0.94 -0.9358 -1.0 3012475 CMLD2_000783 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I15 compound treatment 1.35949E7 -3350000.0 -0.23 -0.2253 -1.0 3132285 CMLD2_000784 CCc1cc2CN(CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I16 compound treatment 5014180.0 -1.19E7 -0.8 -0.8015 -1.0 3012476 CMLD2_000785 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I17 compound treatment 1.02493E7 -6700000.0 -0.45 -0.4499 -1.0 3132408 CMLD2_000786 CO[C@H](/C=N/OCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I18 compound treatment 1.14522E7 -5500000.0 -0.37 -0.3692 -1.0 3012477 CMLD2_000787 CC(=NOCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I19 compound treatment 1.71245E7 175000.0 0.01 0.0118 1.0 3132409 CMLD2_000788 CO/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I20 mock treatment 1.30388E7 -3910000.0 -0.26 -0.2626 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I21 mock treatment 2.33937E7 6440000.0 0.43 0.4328 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I22 mock treatment 5485470.0 -1.15E7 -0.77 -0.7699 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I23 mock treatment 1.28094E7 -4140000.0 -0.28 -0.278 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 I24 mock treatment 2.19789E7 5030000.0 0.34 0.3378 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J01 compound treatment 6274110.0 -1.07E7 -0.72 -0.7169 -1.0 3132410 CMLD2_000789 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)CCC[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J02 compound treatment 9073440.0 -7880000.0 -0.53 -0.5289 -1.0 3012478 CMLD2_000790 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J03 compound treatment 3.12202E7 1.43E7 0.96 0.9584 1.0 3132411 CMLD2_000791 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J04 compound treatment 1.43144E7 -2630000.0 -0.18 -0.177 -1.0 3132412 CMLD2_000792 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J05 mock treatment 2.05198E7 3570000.0 0.24 0.2398 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J06 mock treatment 3.42945E7 1.73E7 1.16 1.1648 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J07 compound treatment 6875780.0 -1.01E7 -0.68 -0.6765 -1.0 3012479 CMLD2_000793 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J08 compound treatment 1.04652E7 -6480000.0 -0.44 -0.4354 -1.0 3012480 CMLD2_000794 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)COCc3ccco3)cc2)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J09 compound treatment 2.09017E7 3950000.0 0.27 0.2654 1.0 3132413 CMLD2_000795 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J10 compound treatment 6342320.0 -1.06E7 -0.71 -0.7123 -1.0 3132414 CMLD2_000796 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCCc5nc(C)c(C)cc45)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J11 compound treatment 2.05716E7 3620000.0 0.24 0.2433 1.0 3132415 CMLD2_000797 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(CC)C4=O)C=C[C@@H]1Oc5ccc(OC)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J12 compound treatment 8003440.0 -8950000.0 -0.6 -0.6008 -1.0 3012481 CMLD2_000798 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J13 compound treatment 4472260.0 -1.25E7 -0.84 -0.8379 -1.0 3132416 CMLD2_000799 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J14 compound treatment 1885790.0 -1.51E7 -1.01 -1.0116 -1.0 3012482 CMLD2_000800 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J15 compound treatment 2.84376E7 1.15E7 0.77 0.7715 1.0 3132417 CMLD2_000801 CCc1cc2CN(CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J16 compound treatment 2.37864E7 6840000.0 0.46 0.4591 1.0 3012484 CMLD2_000802 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J17 compound treatment 6669180.0 -1.03E7 -0.69 -0.6904 -1.0 3132418 CMLD2_000803 CO[C@H](/C=N/OC(C)CN1CCCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J18 compound treatment 5.56458E7 3.87E7 2.6 2.5987 1.0 3012486 CMLD2_000804 CC(CN1CCCCc2nc(C)c(C)cc12)ON=C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J19 compound treatment 8548510.0 -8400000.0 -0.56 -0.5642 -1.0 3132419 CMLD2_000805 CO/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J20 mock treatment 1.88608E7 1910000.0 0.13 0.1284 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J21 mock treatment 1.96238E7 2670000.0 0.18 0.1796 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J22 mock treatment 3988420.0 -1.3E7 -0.87 -0.8704 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J23 mock treatment 1.28197E7 -4130000.0 -0.28 -0.2773 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 J24 mock treatment 1.91228E7 2170000.0 0.15 0.146 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K01 compound treatment 1.90277E7 2080000.0 0.14 0.1396 1.0 3132420 CMLD2_000806 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K02 compound treatment 3.66545E7 1.97E7 1.32 1.3233 1.0 3012487 CMLD2_000807 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K03 compound treatment 1.58096E7 -1140000.0 -0.08 -0.0765 -1.0 3132421 CMLD2_000808 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K04 compound treatment 1.79164E7 967000.0 0.06 0.0649 1.0 3132422 CMLD2_000809 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K05 compound treatment 3.33812E7 1.64E7 1.1 1.1035 1.0 3012488 CMLD2_000810 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K06 compound treatment 3.6718E7 1.98E7 1.33 1.3276 1.0 3132423 CMLD2_000811 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K07 mock treatment 2.02595E7 3310000.0 0.22 0.2223 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K08 mock treatment 1.56135E7 -1340000.0 -0.09 -0.0897 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K09 compound treatment 6082190.0 -1.09E7 -0.73 -0.7298 -1.0 3132424 CMLD2_000812 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K10 compound treatment 1.43579E7 -2590000.0 -0.17 -0.174 -1.0 3011824 CMLD2_000813 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCc5nc(C)c(C)cc45)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K11 compound treatment 2.01031E7 3150000.0 0.21 0.2118 1.0 3132425 CMLD2_000814 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K12 compound treatment 2.21176E7 5170000.0 0.35 0.3471 1.0 3132426 CMLD2_000815 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)c8ccccc8)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K13 compound treatment 1.61192E7 -830000.0 -0.06 -0.0557 -1.0 3011825 CMLD2_000816 CC(=O)OC[C@H]1O[C@@H](O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K14 compound treatment 5.2971E7 3.6E7 2.42 2.4191 1.0 3132547 CMLD2_000817 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K15 mock treatment 1.71708E7 221000.0 0.01 0.0149 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K16 mock treatment 1.76166E7 667000.0 0.04 0.0448 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K17 compound treatment 2.66017E7 9650000.0 0.65 0.6482 1.0 3011826 CMLD2_000818 CO[C@H](/C=N/OC(C)CN1CCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K18 compound treatment 1.71187E7 169000.0 0.01 0.0114 1.0 3132548 CMLD2_000819 CC(CN1CCCc2nc(C)c(C)cc12)ON=C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K19 compound treatment 1.10396E7 -5910000.0 -0.4 -0.3969 -1.0 3011827 CMLD2_000820 CO/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K20 compound treatment 3.32459E7 1.63E7 1.09 1.0944 1.0 3131977 CMLD2_000821 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K21 compound treatment 1.33885E7 -3560000.0 -0.24 -0.2391 -1.0 3132549 CMLD2_000822 C[C@@H]1CC[C@@H]2N(C[C@H](Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K22 compound treatment 1.0137E7 -6810000.0 -0.46 -0.4575 -1.0 3132550 CMLD2_000823 CCO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K23 mock treatment 6015600.0 -1.09E7 -0.73 -0.7343 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 K24 mock treatment 2.44336E7 7480000.0 0.5 0.5026 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L01 compound treatment 1.03511E7 -6600000.0 -0.44 -0.4431 -1.0 3011828 CMLD2_000824 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L02 compound treatment 2.50404E7 8090000.0 0.54 0.5434 1.0 3132551 CMLD2_000825 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L03 compound treatment 8253950.0 -8700000.0 -0.58 -0.5839 -1.0 3011829 CMLD2_000826 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L04 compound treatment 3.40457E7 1.71E7 1.15 1.1481 1.0 3132552 CMLD2_000827 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L05 compound treatment 2.75621E7 1.06E7 0.71 0.7127 1.0 3132553 CMLD2_000828 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L06 compound treatment 2.19706E7 5020000.0 0.34 0.3372 1.0 3011830 CMLD2_000829 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L07 mock treatment 3.91944E7 2.22E7 1.49 1.4939 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L08 mock treatment 1.951E7 2560000.0 0.17 0.172 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L09 compound treatment 2.0564E7 3610000.0 0.24 0.2427 1.0 3132554 CMLD2_000830 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)COCc2ccco2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L10 compound treatment 3.42031E7 1.73E7 1.16 1.1587 1.0 3011831 CMLD2_000831 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L11 compound treatment 2.71054E7 1.02E7 0.68 0.682 1.0 3132555 CMLD2_000832 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCCc5nc(C)c(C)cc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L12 compound treatment 1.9076E7 2130000.0 0.14 0.1428 1.0 3132556 CMLD2_000833 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1Oc7ccc(OC)cc7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L13 compound treatment 1.27146E7 -4230000.0 -0.28 -0.2844 -1.0 3011832 CMLD2_000834 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L14 compound treatment 4.7161E7 3.02E7 2.03 2.0289 1.0 3132557 CMLD2_000835 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L15 mock treatment 8867420.0 -8080000.0 -0.54 -0.5427 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L16 mock treatment 2.20198E7 5070000.0 0.34 0.3405 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L17 compound treatment 2.69438E7 9990000.0 0.67 0.6712 1.0 3132558 CMLD2_000836 CO[C@H](/C=N/OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L18 compound treatment 2.39137E7 6960000.0 0.47 0.4677 1.0 3011833 CMLD2_000837 CC(=NOC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L19 compound treatment 3.02252E7 1.33E7 0.89 0.8915 1.0 3011834 CMLD2_000838 CO/N=C/c1ccc(cc1)C(=O)N2[C@@H](CC[C@H](C)[C@H]2c3ccc(C)cc3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L20 compound treatment 1.6652E7 -297000.0 -0.02 -0.02 -1.0 3132559 CMLD2_000839 CCC(=O)[C@]1(O)[C@H]2CCOC(=O)C2=C3N(Cc4ccccc4)C(=C([C@H](N3C1=O)c5ccccc5)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L21 compound treatment 1.03364E7 -6610000.0 -0.44 -0.4441 -1.0 3132529 CMLD2_000840 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L22 compound treatment 1.17097E7 -5240000.0 -0.35 -0.3519 -1.0 3011835 CMLD2_000841 CO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)C(=O)C)[C@@H](C)[C@H](OC)c1ccccc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L23 mock treatment 3625340.0 -1.33E7 -0.89 -0.8948 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 L24 mock treatment 8899230.0 -8050000.0 -0.54 -0.5406 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M01 compound treatment 1.86164E7 1670000.0 0.11 0.112 1.0 3132560 CMLD2_000842 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)CCC[C@H]1C)[C@@H](O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M02 compound treatment 1.28636E7 -4090000.0 -0.27 -0.2744 -1.0 3011836 CMLD2_000843 C[C@H]/1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C\C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M03 compound treatment 2.57648E7 8820000.0 0.59 0.592 1.0 3132561 CMLD2_000844 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M04 compound treatment 1.4477E7 -2470000.0 -0.17 -0.166 -1.0 3132562 CMLD2_000845 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M05 compound treatment 2.33391E7 6390000.0 0.43 0.4291 1.0 3011870 CMLD2_000846 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M06 compound treatment 3.07421E7 1.38E7 0.93 0.9263 1.0 3132563 CMLD2_000847 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M07 compound treatment 1.97377E7 2790000.0 0.19 0.1873 1.0 3011871 CMLD2_000848 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M08 compound treatment 2.63832E7 9430000.0 0.63 0.6335 1.0 3132564 CMLD2_000849 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)cc2)c5ccc(C)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M09 mock treatment 3.17996E7 1.49E7 1.0 0.9973 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M10 mock treatment 1.90484E7 2100000.0 0.14 0.141 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M11 compound treatment 3.77903E7 2.08E7 1.4 1.3996 1.0 3011872 CMLD2_000850 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCc5nc(C)c(C)cc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M12 compound treatment 2.37046E7 6760000.0 0.45 0.4537 1.0 3132565 CMLD2_000851 CC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M13 mock treatment 2.91194E7 1.22E7 0.82 0.8173 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M14 mock treatment 2.0372E7 3420000.0 0.23 0.2299 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M15 compound treatment 1.22702E7 -4680000.0 -0.31 -0.3142 -1.0 3132566 CMLD2_000852 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M16 compound treatment 1.62757E7 -674000.0 -0.05 -0.0452 -1.0 3011873 CMLD2_000853 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M17 compound treatment 2.61538E7 9200000.0 0.62 0.6181 1.0 3130490 CMLD2_000854 CO[C@H](/C=N/O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M18 compound treatment 2.23144E7 5370000.0 0.36 0.3603 1.0 3011875 CMLD2_000855 CC(=NOC1C=C[C@@H](CC=C)O[C@@H]1CO)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M19 compound treatment 2.09782E7 4030000.0 0.27 0.2706 1.0 3130491 CMLD2_000856 CO/N=C/[C@@H](NS(=O)(=O)c1ccc(C)cc1)[C@H](C)\C=C\CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M20 compound treatment 8418780.0 -8530000.0 -0.57 -0.5729 -1.0 3132404 CMLD2_000857 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M21 compound treatment 1.11053E7 -5840000.0 -0.39 -0.3925 -1.0 3011876 CMLD2_000858 C[C@H]1CC[C@@H]2N(C[C@@H](CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M22 compound treatment 2.51113E7 8160000.0 0.55 0.5481 1.0 3130492 CMLD2_000859 CO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1ccccc1Br 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M23 mock treatment 1.11376E7 -5810000.0 -0.39 -0.3903 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 M24 mock treatment 4.06361E7 2.37E7 1.59 1.5907 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N01 compound treatment 1.18143E7 -5140000.0 -0.34 -0.3448 -1.0 3130493 CMLD2_000860 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)CCC[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N02 compound treatment 1.8115E7 1170000.0 0.08 0.0783 1.0 3011877 CMLD2_000861 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N03 compound treatment 1.56247E7 -1320000.0 -0.09 -0.089 -1.0 3130494 CMLD2_000862 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)c5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N04 compound treatment 8173340.0 -8780000.0 -0.59 -0.5894 -1.0 3130495 CMLD2_000863 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N05 compound treatment 2.5599E7 8650000.0 0.58 0.5809 1.0 3011878 CMLD2_000864 CC(=O)OC[C@H]1O[C@H](C/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N06 compound treatment 1.04827E7 -6470000.0 -0.43 -0.4343 -1.0 3130496 CMLD2_000865 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N07 compound treatment 1.26366E7 -4310000.0 -0.29 -0.2896 -1.0 3011879 CMLD2_000866 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N08 compound treatment 4104050.0 -1.28E7 -0.86 -0.8626 -1.0 3130497 CMLD2_000867 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N09 mock treatment 1.86081E7 1660000.0 0.11 0.1114 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N10 mock treatment 2.72992E7 1.03E7 0.7 0.695 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N11 compound treatment 1.12266E7 -5720000.0 -0.38 -0.3843 -1.0 3011881 CMLD2_000868 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N12 compound treatment 9854340.0 -7100000.0 -0.48 -0.4765 -1.0 3130498 CMLD2_000869 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N13 mock treatment 2.92508E7 1.23E7 0.83 0.8261 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N14 mock treatment 1.07995E7 -6150000.0 -0.41 -0.413 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N15 compound treatment 1.30482E7 -3900000.0 -0.26 -0.262 -1.0 3130499 CMLD2_000870 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N16 compound treatment 8153470.0 -8800000.0 -0.59 -0.5907 -1.0 3011882 CMLD2_000871 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N17 compound treatment 3839780.0 -1.31E7 -0.88 -0.8804 -1.0 3130500 CMLD2_000872 CO[C@H](/C=N/OC[C@@H](O)COCc1ccco1)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N18 compound treatment 1607120.0 -1.53E7 -1.03 -1.0303 -1.0 3011884 CMLD2_000873 CC(=NOC[C@@H](O)COCc1ccco1)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N19 compound treatment 1918420.0 -1.5E7 -1.01 -1.0094 -1.0 3130501 CMLD2_000874 CO/N=C\1/[C@H](O)[C@H](Oc2ccc(OC)cc12)c3cccc(OC)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N20 compound treatment 1.02005E7 -6750000.0 -0.45 -0.4532 -1.0 3131849 CMLD2_000875 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N21 compound treatment 2.13478E7 4400000.0 0.3 0.2954 1.0 3011885 CMLD2_000876 C[C@@H]1CC[C@@H]2N(C[C@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N22 compound treatment 8699360.0 -8250000.0 -0.55 -0.554 -1.0 3130502 CMLD2_000877 CO[C@@H]([C@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)/C=C/CC(=O)OC)C2CCCCC2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N23 mock treatment 8465540.0 -8480000.0 -0.57 -0.5697 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 N24 mock treatment 1.59056E7 -1040000.0 -0.07 -0.0701 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O01 compound treatment 7490660.0 -9460000.0 -0.64 -0.6352 -1.0 3011886 CMLD2_000878 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O02 compound treatment 1.76571E7 708000.0 0.05 0.0475 1.0 3130503 CMLD2_000879 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O03 compound treatment 1.30925E7 -3860000.0 -0.26 -0.259 -1.0 3130504 CMLD2_000880 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O04 compound treatment 1.22106E7 -4740000.0 -0.32 -0.3182 -1.0 3130505 CMLD2_000881 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O05 compound treatment 1.34177E7 -3530000.0 -0.24 -0.2372 -1.0 3130506 CMLD2_000882 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)COCc2ccco2)C=C[C@@H]1OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O06 compound treatment 4730530.0 -1.22E7 -0.82 -0.8206 -1.0 3011921 CMLD2_000883 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O07 compound treatment 1.01858E7 -6760000.0 -0.45 -0.4542 -1.0 3130507 CMLD2_000884 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O08 compound treatment 2.00919E7 3140000.0 0.21 0.211 1.0 3130508 CMLD2_000885 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)cc2)c5ccc(C)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O09 compound treatment 1.26621E7 -4290000.0 -0.29 -0.2879 -1.0 3011922 CMLD2_000886 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O10 compound treatment 9951460.0 -7000000.0 -0.47 -0.4699 -1.0 3130509 CMLD2_000887 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O11 mock treatment 7568210.0 -9380000.0 -0.63 -0.63 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O12 mock treatment 1.35468E7 -3400000.0 -0.23 -0.2285 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O13 compound treatment 1.45836E7 -2370000.0 -0.16 -0.1589 -1.0 3011925 CMLD2_000888 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/[C@@H](C)[C@H](OCc3ccccc3)C(C)C)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O14 compound treatment 1.84871E7 1540000.0 0.1 0.1033 1.0 3130636 CMLD2_000889 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O15 compound treatment 1.6823E7 -126000.0 -0.01 -0.0085 -1.0 3011927 CMLD2_000890 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O16 compound treatment 2954050.0 -1.4E7 -0.94 -0.9399 -1.0 3130637 CMLD2_000891 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@@H]6COC[C@H]6O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O17 compound treatment 9208500.0 -7740000.0 -0.52 -0.5198 -1.0 3130638 CMLD2_000892 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@@H]2COC[C@H]2O)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O18 compound treatment 1.77997E7 850000.0 0.06 0.0571 1.0 3011928 CMLD2_000893 C[C@@H](ON=C(C)C)c1cn(nn1)[C@@H]2COC[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O19 compound treatment 1.22647E7 -4680000.0 -0.31 -0.3146 -1.0 3130639 CMLD2_000894 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O20 compound treatment 1.88737E7 1920000.0 0.13 0.1292 1.0 3011929 CMLD2_000895 CCN1C(=C([C@H](N2C(=O)[C@@](O)(CC(=C12)C(=O)C)C(=O)OC)c3ccccc3)C(=O)OC)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O21 compound treatment 3.35978E7 1.66E7 1.12 1.118 1.0 3130640 CMLD2_000896 C[C@@H]1CC[C@@H]2N(C[C@@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O22 mock treatment 2.84526E7 1.15E7 0.77 0.7725 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O23 mock treatment 1.69244E7 -24900.0 0.0 -0.0017 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 O24 mock treatment 1.29284E7 -4020000.0 -0.27 -0.27 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P01 compound treatment 2.16166E7 4670000.0 0.31 0.3134 1.0 3011930 CMLD2_000897 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P02 compound treatment 2.2922E7 5970000.0 0.4 0.4011 1.0 3130641 CMLD2_000898 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P03 compound treatment 1.50604E7 -1890000.0 -0.13 -0.1269 -1.0 3130642 CMLD2_000899 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P04 compound treatment 7710690.0 -9240000.0 -0.62 -0.6204 -1.0 3130643 CMLD2_000900 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@@H]5COC[C@H]5O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P05 compound treatment 2.12583E7 4310000.0 0.29 0.2894 1.0 3011932 CMLD2_000901 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@@H]3COC[C@H]3O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P06 compound treatment 1.98271E7 2880000.0 0.19 0.1933 1.0 3130644 CMLD2_000902 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P07 compound treatment 6597790.0 -1.04E7 -0.7 -0.6952 -1.0 3011933 CMLD2_000903 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P08 compound treatment 1.38278E7 -3120000.0 -0.21 -0.2096 -1.0 3130645 CMLD2_000904 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)cc2)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P09 compound treatment 1.08951E7 -6050000.0 -0.41 -0.4066 -1.0 3011935 CMLD2_000905 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P10 compound treatment 0.0 -1.69E7 -1.14 -1.1382 -1.0 3130646 CMLD2_000906 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)COCc4ccco4)/[C@@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P11 mock treatment 3.0907E7 1.4E7 0.94 0.9373 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P12 mock treatment 2.52289E7 8280000.0 0.56 0.556 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P13 compound treatment 1.05257E7 -6420000.0 -0.43 -0.4314 -1.0 3130647 CMLD2_000907 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C)C=C[C@@H]1Oc3ccc(OC)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P14 compound treatment 1.85578E7 1610000.0 0.11 0.108 1.0 3011936 CMLD2_000908 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P15 compound treatment 6757230.0 -1.02E7 -0.68 -0.6845 -1.0 3130648 CMLD2_000909 CCc1cc2CN(CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)CCc2nc1CC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P16 compound treatment 1.19684E7 -4980000.0 -0.33 -0.3345 -1.0 3130649 CMLD2_000910 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P17 compound treatment 1.80139E7 1060000.0 0.07 0.0715 1.0 3011937 CMLD2_000911 CO[C@H](/C=N/O[C@@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P18 compound treatment 1.97835E7 2830000.0 0.19 0.1903 1.0 3130650 CMLD2_000912 C[C@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P19 compound treatment 2.43121E7 7360000.0 0.49 0.4944 1.0 3011939 CMLD2_000913 CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P20 compound treatment 1.94464E7 2500000.0 0.17 0.1677 1.0 3131985 CMLD2_000914 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P21 compound treatment 3693550.0 -1.33E7 -0.89 -0.8902 -1.0 3130651 CMLD2_000915 C[C@@H]1CC[C@@H]2N(C[C@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P22 mock treatment 1.1512E7 -5440000.0 -0.37 -0.3651 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P23 mock treatment 9009070.0 -7940000.0 -0.53 -0.5332 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2111 P24 mock treatment 8512270.0 -8440000.0 -0.57 -0.5666 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A01 compound treatment 9322450.0 -5840000.0 -0.39 -0.3919 -1.0 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A02 compound treatment 8382540.0 -6780000.0 -0.45 -0.455 -1.0 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A03 compound treatment 1.28484E7 -2310000.0 -0.16 -0.1551 -1.0 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A04 compound treatment 1.92352E7 4080000.0 0.27 0.2738 1.0 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A05 compound treatment 7598670.0 -7560000.0 -0.51 -0.5076 -1.0 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A06 compound treatment 1.74614E7 2300000.0 0.15 0.1547 1.0 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A07 compound treatment 5800660.0 -9360000.0 -0.63 -0.6284 -1.0 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A08 compound treatment 7645900.0 -7510000.0 -0.5 -0.5045 -1.0 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A09 compound treatment 1.633E7 1170000.0 0.08 0.0787 1.0 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A10 compound treatment 2.14486E7 6290000.0 0.42 0.4225 1.0 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A11 compound treatment 1.34049E7 -1750000.0 -0.12 -0.1177 -1.0 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A12 compound treatment 1.43156E7 -842000.0 -0.06 -0.0566 -1.0 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A13 mock treatment 2.90116E7 1.39E7 0.93 0.9304 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A14 mock treatment 7706560.0 -7450000.0 -0.5 -0.5004 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A15 compound treatment 6756260.0 -8400000.0 -0.56 -0.5642 -1.0 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A16 compound treatment 2.47132E7 9560000.0 0.64 0.6417 1.0 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A17 compound treatment 6688780.0 -8470000.0 -0.57 -0.5687 -1.0 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A18 compound treatment 7028500.0 -8130000.0 -0.55 -0.5459 -1.0 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A19 compound treatment 2.2511E7 7350000.0 0.49 0.4938 1.0 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A20 compound treatment 3439860.0 -1.17E7 -0.79 -0.7869 -1.0 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A21 compound treatment 2.94606E7 1.43E7 0.96 0.9605 1.0 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A22 compound treatment 1.46865E7 -471000.0 -0.03 -0.0317 -1.0 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A23 compound treatment 941760.0 -1.42E7 -0.95 -0.9547 -1.0 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 A24 compound treatment 3306190.0 -1.19E7 -0.8 -0.7959 -1.0 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B01 compound treatment 3.1663E7 1.65E7 1.11 1.1084 1.0 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B02 compound treatment 1.29321E7 -2230000.0 -0.15 -0.1495 -1.0 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B03 compound treatment 1.57226E7 565000.0 0.04 0.0379 1.0 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B04 compound treatment 1.41728E7 -985000.0 -0.07 -0.0661 -1.0 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B05 compound treatment 9315470.0 -5840000.0 -0.39 -0.3923 -1.0 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B06 compound treatment 1.48026E7 -355000.0 -0.02 -0.0239 -1.0 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B07 compound treatment 2.85753E7 1.34E7 0.9 0.9011 1.0 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B08 compound treatment 5414740.0 -9740000.0 -0.65 -0.6543 -1.0 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B09 compound treatment 1.03967E7 -4760000.0 -0.32 -0.3197 -1.0 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B10 compound treatment 1.36932E7 -1460000.0 -0.1 -0.0984 -1.0 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B11 compound treatment 2859230.0 -1.23E7 -0.83 -0.8259 -1.0 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B12 compound treatment 4912240.0 -1.02E7 -0.69 -0.688 -1.0 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B13 mock treatment 6.06732E7 4.55E7 3.06 3.0566 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B14 mock treatment 1.45782E7 -580000.0 -0.04 -0.0389 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B15 compound treatment 1.52745E7 117000.0 0.01 0.0078 1.0 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B16 compound treatment 0.0 -1.52E7 -1.02 -1.0179 -1.0 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B17 compound treatment 2.52011E7 1.0E7 0.67 0.6745 1.0 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B18 compound treatment 3688880.0 -1.15E7 -0.77 -0.7702 -1.0 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B19 compound treatment 2.15337E7 6380000.0 0.43 0.4282 1.0 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B20 compound treatment 1.10823E7 -4080000.0 -0.27 -0.2737 -1.0 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B21 compound treatment 2.47095E7 9550000.0 0.64 0.6414 1.0 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B22 compound treatment 6201620.0 -8960000.0 -0.6 -0.6015 -1.0 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B23 compound treatment 1.48805E7 -277000.0 -0.02 -0.0186 -1.0 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 B24 compound treatment 1722780.0 -1.34E7 -0.9 -0.9022 -1.0 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C01 compound treatment 1.66858E7 1530000.0 0.1 0.1026 1.0 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C02 compound treatment 2.01055E7 4950000.0 0.33 0.3323 1.0 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C03 compound treatment 1.17267E7 -3430000.0 -0.23 -0.2304 -1.0 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C04 compound treatment 1.06059E7 -4550000.0 -0.31 -0.3057 -1.0 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C05 compound treatment 2.24408E7 7280000.0 0.49 0.4891 1.0 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C06 compound treatment 2.68216E7 1.17E7 0.78 0.7833 1.0 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C07 compound treatment 1.93656E7 4210000.0 0.28 0.2826 1.0 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C08 compound treatment 2.48062E7 9650000.0 0.65 0.6479 1.0 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C09 compound treatment 1.91094E7 3950000.0 0.27 0.2654 1.0 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C10 compound treatment 3568480.0 -1.16E7 -0.78 -0.7783 -1.0 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C11 mock treatment 1.50026E7 -155000.0 -0.01 -0.0104 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C12 mock treatment 2.71193E7 1.2E7 0.8 0.8033 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C13 compound treatment 3.20117E7 1.69E7 1.13 1.1318 1.0 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C14 compound treatment 6106270.0 -9050000.0 -0.61 -0.6079 -1.0 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C15 mock treatment 1.21235E7 -3030000.0 -0.2 -0.2038 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C16 mock treatment 1887980.0 -1.33E7 -0.89 -0.8911 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C17 compound treatment 3.60057E7 2.08E7 1.4 1.4001 1.0 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C18 compound treatment 2.75651E7 1.24E7 0.83 0.8332 1.0 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C19 compound treatment 1.34402E7 -1720000.0 -0.12 -0.1153 -1.0 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C20 compound treatment 1.59673E7 809000.0 0.05 0.0544 1.0 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C21 compound treatment 1.14629E7 -3690000.0 -0.25 -0.2481 -1.0 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C22 compound treatment 1.73659E7 2210000.0 0.15 0.1483 1.0 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C23 compound treatment 2.26844E7 7530000.0 0.51 0.5055 1.0 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 C24 compound treatment 5193730.0 -9960000.0 -0.67 -0.6691 -1.0 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D01 compound treatment 4.01977E7 2.5E7 1.68 1.6816 1.0 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D02 compound treatment 8511020.0 -6650000.0 -0.45 -0.4464 -1.0 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D03 compound treatment 1.06536E7 -4500000.0 -0.3 -0.3025 -1.0 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D04 compound treatment 2.21381E7 6980000.0 0.47 0.4688 1.0 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D05 compound treatment 1.5367E7 209000.0 0.01 0.014 1.0 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D06 compound treatment 3577360.0 -1.16E7 -0.78 -0.7777 -1.0 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D07 compound treatment 1.28525E7 -2310000.0 -0.15 -0.1548 -1.0 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D08 compound treatment 2.07801E7 5620000.0 0.38 0.3776 1.0 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D09 compound treatment 1.60676E7 910000.0 0.06 0.0611 1.0 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D10 compound treatment 1.76399E7 2480000.0 0.17 0.1667 1.0 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D11 mock treatment 2.69563E7 1.18E7 0.79 0.7923 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D12 mock treatment 2596980.0 -1.26E7 -0.84 -0.8435 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D13 compound treatment 2.58595E7 1.07E7 0.72 0.7187 1.0 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D14 compound treatment 2.06515E7 5490000.0 0.37 0.3689 1.0 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D15 mock treatment 6421420.0 -8740000.0 -0.59 -0.5867 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D16 mock treatment 4296430.0 -1.09E7 -0.73 -0.7294 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D17 compound treatment 1.73761E7 2220000.0 0.15 0.149 1.0 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D18 compound treatment 5838990.0 -9320000.0 -0.63 -0.6258 -1.0 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D19 compound treatment 8793740.0 -6360000.0 -0.43 -0.4274 -1.0 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D20 compound treatment 3881950.0 -1.13E7 -0.76 -0.7572 -1.0 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D21 compound treatment 1.77476E7 2590000.0 0.17 0.1739 1.0 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D22 compound treatment 3.32775E7 1.81E7 1.22 1.2168 1.0 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D23 compound treatment 1.55325E7 375000.0 0.03 0.0252 1.0 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 D24 compound treatment 1.50675E7 -90300.0 -0.01 -0.0061 -1.0 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E01 mock treatment 3.66551E7 2.15E7 1.44 1.4437 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E02 mock treatment 2.43369E7 9180000.0 0.62 0.6164 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E03 compound treatment 1.41193E7 -1040000.0 -0.07 -0.0697 -1.0 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E04 compound treatment 2.4084E7 8930000.0 0.6 0.5994 1.0 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E05 compound treatment 3.76146E7 2.25E7 1.51 1.5081 1.0 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E06 compound treatment 1.98788E7 4720000.0 0.32 0.317 1.0 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E07 compound treatment 1.20988E7 -3060000.0 -0.21 -0.2054 -1.0 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E08 compound treatment 1.34765E7 -1680000.0 -0.11 -0.1129 -1.0 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E09 mock treatment 2.12816E7 6120000.0 0.41 0.4112 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E10 mock treatment 1.4538E7 -620000.0 -0.04 -0.0416 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E11 compound treatment 7876100.0 -7280000.0 -0.49 -0.489 -1.0 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E12 compound treatment 4.50881E7 2.99E7 2.01 2.01 1.0 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E13 compound treatment 4402660.0 -1.08E7 -0.72 -0.7223 -1.0 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E14 compound treatment 2.11655E7 6010000.0 0.4 0.4034 1.0 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E15 compound treatment 1.83329E7 3180000.0 0.21 0.2132 1.0 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E16 compound treatment 6694260.0 -8460000.0 -0.57 -0.5684 -1.0 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E17 mock treatment 4278140.0 -1.09E7 -0.73 -0.7306 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E18 mock treatment 1.09564E7 -4200000.0 -0.28 -0.2821 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E19 compound treatment 1218820.0 -1.39E7 -0.94 -0.9361 -1.0 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E20 compound treatment 2450850.0 -1.27E7 -0.85 -0.8533 -1.0 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E21 compound treatment 1.57529E7 595000.0 0.04 0.04 1.0 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E22 compound treatment 9448160.0 -5710000.0 -0.38 -0.3834 -1.0 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E23 compound treatment 6293820.0 -8860000.0 -0.6 -0.5953 -1.0 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 E24 compound treatment 1.96122E7 4450000.0 0.3 0.2991 1.0 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F01 mock treatment 1.70384E7 1880000.0 0.13 0.1263 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F02 mock treatment 1.31923E7 -1970000.0 -0.13 -0.132 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F03 compound treatment 3.08671E7 1.57E7 1.05 1.055 1.0 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F04 compound treatment 1.88806E7 3720000.0 0.25 0.25 1.0 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F05 compound treatment 1.84407E7 3280000.0 0.22 0.2205 1.0 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F06 compound treatment 1.46196E7 -538000.0 -0.04 -0.0361 -1.0 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F07 compound treatment 1.80035E7 2850000.0 0.19 0.1911 1.0 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F08 compound treatment 2.45919E7 9430000.0 0.63 0.6336 1.0 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F09 mock treatment 1.79368E7 2780000.0 0.19 0.1866 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F10 mock treatment 1.49603E7 -198000.0 -0.01 -0.0133 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F11 compound treatment 2.26709E7 7510000.0 0.5 0.5045 1.0 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F12 compound treatment 2.91664E7 1.4E7 0.94 0.9408 1.0 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F13 compound treatment 1506590.0 -1.37E7 -0.92 -0.9168 -1.0 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F14 compound treatment 8212850.0 -6940000.0 -0.47 -0.4664 -1.0 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F15 compound treatment 1.0273E7 -4880000.0 -0.33 -0.328 -1.0 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F16 compound treatment 0.0 -1.52E7 -1.02 -1.0179 -1.0 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F17 mock treatment 9793780.0 -5360000.0 -0.36 -0.3602 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F18 mock treatment 2995700.0 -1.22E7 -0.82 -0.8168 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F19 compound treatment 6342560.0 -8820000.0 -0.59 -0.592 -1.0 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F20 compound treatment 2.24104E7 7250000.0 0.49 0.4871 1.0 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F21 compound treatment 1.19312E7 -3230000.0 -0.22 -0.2167 -1.0 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F22 compound treatment 1.34803E7 -1680000.0 -0.11 -0.1127 -1.0 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F23 compound treatment 9036960.0 -6120000.0 -0.41 -0.411 -1.0 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 F24 compound treatment 1.01341E7 -5020000.0 -0.34 -0.3374 -1.0 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G01 compound treatment 1.30238E7 -2130000.0 -0.14 -0.1433 -1.0 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G02 compound treatment 9978190.0 -5180000.0 -0.35 -0.3478 -1.0 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G03 mock treatment 3.20628E7 1.69E7 1.14 1.1353 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G04 mock treatment 6979170.0 -8180000.0 -0.55 -0.5492 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G05 compound treatment 9854620.0 -5300000.0 -0.36 -0.3561 -1.0 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G06 compound treatment 1.48009E7 -357000.0 -0.02 -0.024 -1.0 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G07 compound treatment 1.41645E7 -993000.0 -0.07 -0.0667 -1.0 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G08 compound treatment 2.06022E7 5440000.0 0.37 0.3656 1.0 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G09 compound treatment 1.78041E7 2650000.0 0.18 0.1777 1.0 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G10 compound treatment 3.39408E7 1.88E7 1.26 1.2614 1.0 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G11 compound treatment 5954290.0 -9200000.0 -0.62 -0.6181 -1.0 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G12 compound treatment 1707660.0 -1.35E7 -0.9 -0.9033 -1.0 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G13 compound treatment 2.34826E7 8320000.0 0.56 0.5591 1.0 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G14 compound treatment 1.48331E7 -325000.0 -0.02 -0.0218 -1.0 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G15 compound treatment 1.27549E7 -2400000.0 -0.16 -0.1614 -1.0 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G16 compound treatment 2.05612E7 5400000.0 0.36 0.3629 1.0 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G17 compound treatment 1.6362E7 1200000.0 0.08 0.0809 1.0 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G18 compound treatment 3.61287E7 2.1E7 1.41 1.4083 1.0 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G19 mock treatment 7889810.0 -7270000.0 -0.49 -0.4881 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G20 mock treatment 1.75348E7 2380000.0 0.16 0.1596 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G21 compound treatment 4721280.0 -1.04E7 -0.7 -0.7009 -1.0 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G22 compound treatment 6398640.0 -8760000.0 -0.59 -0.5882 -1.0 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G23 compound treatment 1.2174E7 -2980000.0 -0.2 -0.2004 -1.0 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 G24 compound treatment 1.63237E7 1170000.0 0.08 0.0783 1.0 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H01 compound treatment 1.97175E7 4560000.0 0.31 0.3062 1.0 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H02 compound treatment 6822080.0 -8340000.0 -0.56 -0.5598 -1.0 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H03 mock treatment 7977180.0 -7180000.0 -0.48 -0.4822 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H04 mock treatment 1.21333E7 -3020000.0 -0.2 -0.2031 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H05 compound treatment 2.56838E7 1.05E7 0.71 0.7069 1.0 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H06 compound treatment 4887600.0 -1.03E7 -0.69 -0.6897 -1.0 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H07 compound treatment 2.63106E7 1.12E7 0.75 0.749 1.0 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H08 mock treatment 1.37717E7 -1390000.0 -0.09 -0.0931 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H09 compound treatment 1.76259E7 2470000.0 0.17 0.1657 1.0 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H10 mock treatment 1.69012E7 1740000.0 0.12 0.1171 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H11 compound treatment 4.30981E7 2.79E7 1.88 1.8763 1.0 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H12 mock treatment 9467280.0 -5690000.0 -0.38 -0.3822 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H13 compound treatment 2.51103E7 9950000.0 0.67 0.6684 1.0 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H14 mock treatment 3.45015E7 1.93E7 1.3 1.299 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H15 compound treatment 1660110.0 -1.35E7 -0.91 -0.9064 -1.0 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H16 mock treatment 1.16322E7 -3530000.0 -0.24 -0.2368 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H17 compound treatment 2.33849E7 8230000.0 0.55 0.5525 1.0 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H18 mock treatment 2.32721E7 8110000.0 0.54 0.5449 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H19 mock treatment 8474750.0 -6680000.0 -0.45 -0.4488 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H20 mock treatment 2.36121E7 8450000.0 0.57 0.5678 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H21 compound treatment 1.61653E7 1010000.0 0.07 0.0677 1.0 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H22 mock treatment 1.37608E7 -1400000.0 -0.09 -0.0938 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H23 compound treatment 2.62022E7 1.1E7 0.74 0.7417 1.0 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 H24 mock treatment 2.00454E7 4890000.0 0.33 0.3282 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I01 compound treatment 1.2298E7 -2860000.0 -0.19 -0.1921 -1.0 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I02 compound treatment 2.4781E7 9620000.0 0.65 0.6463 1.0 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I03 compound treatment 1.68372E7 1680000.0 0.11 0.1128 1.0 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I04 compound treatment 1.82084E7 3050000.0 0.2 0.2049 1.0 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I05 mock treatment 1.15718E7 -3590000.0 -0.24 -0.2408 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I06 mock treatment 2.37498E7 8590000.0 0.58 0.577 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I07 compound treatment 4.76456E7 3.25E7 2.18 2.1817 1.0 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I08 compound treatment 4.26127E7 2.75E7 1.84 1.8437 1.0 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I09 compound treatment 2.43533E7 9200000.0 0.62 0.6175 1.0 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I10 compound treatment 1.16255E7 -3530000.0 -0.24 -0.2372 -1.0 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I11 compound treatment 1.20098E7 -3150000.0 -0.21 -0.2114 -1.0 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I12 compound treatment 8632370.0 -6530000.0 -0.44 -0.4382 -1.0 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I13 compound treatment 4866020.0 -1.03E7 -0.69 -0.6912 -1.0 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I14 compound treatment 1.49751E7 -183000.0 -0.01 -0.0123 -1.0 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I15 compound treatment 1.76018E7 2440000.0 0.16 0.1641 1.0 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I16 compound treatment 2752670.0 -1.24E7 -0.83 -0.8331 -1.0 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I17 compound treatment 1.77676E7 2610000.0 0.18 0.1753 1.0 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I18 compound treatment 1.89164E7 3760000.0 0.25 0.2524 1.0 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I19 compound treatment 2.25359E7 7380000.0 0.5 0.4955 1.0 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I20 compound treatment 1.05894E7 -4570000.0 -0.31 -0.3068 -1.0 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I21 mock treatment 5592560.0 -9570000.0 -0.64 -0.6424 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I22 mock treatment 2443630.0 -1.27E7 -0.85 -0.8538 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I23 compound treatment 8592030.0 -6570000.0 -0.44 -0.4409 -1.0 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 I24 compound treatment 5732110.0 -9430000.0 -0.63 -0.633 -1.0 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J01 compound treatment 2.02745E7 5120000.0 0.34 0.3436 1.0 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J02 mock treatment 3.06239E7 1.55E7 1.04 1.0386 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J03 compound treatment 2.6312E7 1.12E7 0.75 0.7491 1.0 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J04 mock treatment 1.55369E7 379000.0 0.03 0.0255 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J05 mock treatment 6679860.0 -8480000.0 -0.57 -0.5693 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J06 mock treatment 2.34784E7 8320000.0 0.56 0.5588 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J07 compound treatment 1.45406E7 -617000.0 -0.04 -0.0414 -1.0 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J08 mock treatment 2.37124E7 8550000.0 0.57 0.5745 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J09 compound treatment 1.05592E7 -4600000.0 -0.31 -0.3088 -1.0 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J10 mock treatment 1.14081E7 -3750000.0 -0.25 -0.2518 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J11 compound treatment 5176860.0 -9980000.0 -0.67 -0.6703 -1.0 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J12 mock treatment 4954990.0 -1.02E7 -0.69 -0.6852 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J13 compound treatment 3807500.0 -1.14E7 -0.76 -0.7622 -1.0 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J14 mock treatment 2.06557E7 5500000.0 0.37 0.3692 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J15 compound treatment 7841060.0 -7320000.0 -0.49 -0.4914 -1.0 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J16 mock treatment 1.75411E7 2380000.0 0.16 0.1601 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J17 compound treatment 6180480.0 -8980000.0 -0.6 -0.6029 -1.0 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J18 mock treatment 8089070.0 -7070000.0 -0.47 -0.4747 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J19 compound treatment 1.62362E7 1080000.0 0.07 0.0724 1.0 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J20 mock treatment 1.20617E7 -3100000.0 -0.21 -0.2079 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J21 mock treatment 3.51433E7 2.0E7 1.34 1.3421 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J22 mock treatment 1.10311E7 -4130000.0 -0.28 -0.2771 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J23 compound treatment 9931580.0 -5230000.0 -0.35 -0.351 -1.0 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 J24 mock treatment 1.51077E7 -50100.0 0.0 -0.0034 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K01 compound treatment 8070340.0 -7090000.0 -0.48 -0.476 -1.0 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K02 compound treatment 8177920.0 -6980000.0 -0.47 -0.4687 -1.0 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K03 compound treatment 1.10065E9 1.09E9 72.9 72.8968 1.0 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K04 compound treatment 1.0796E7 -4360000.0 -0.29 -0.2929 -1.0 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K05 compound treatment 9080400.0 -6080000.0 -0.41 -0.4081 -1.0 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K06 compound treatment 4.8797E7 3.36E7 2.26 2.2591 1.0 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K07 mock treatment 9089780.0 -6070000.0 -0.41 -0.4075 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K08 mock treatment 1.67908E7 1630000.0 0.11 0.1097 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K09 compound treatment 1.53636E7 206000.0 0.01 0.0138 1.0 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K10 compound treatment 0.0 -1.52E7 -1.02 -1.0179 -1.0 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K11 compound treatment 1.31336E7 -2020000.0 -0.14 -0.1359 -1.0 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K12 compound treatment 1.57916E7 634000.0 0.04 0.0426 1.0 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K13 compound treatment 9221280.0 -5940000.0 -0.4 -0.3987 -1.0 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K14 compound treatment 9286020.0 -5870000.0 -0.39 -0.3943 -1.0 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K15 mock treatment 1.51338E7 -24000.0 0.0 -0.0016 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K16 mock treatment 4.12607E7 2.61E7 1.75 1.753 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K17 compound treatment 1.91726E7 4010000.0 0.27 0.2696 1.0 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K18 compound treatment 1.8236E7 3080000.0 0.21 0.2067 1.0 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K19 compound treatment 1.31919E7 -1970000.0 -0.13 -0.132 -1.0 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K20 compound treatment 1.44417E7 -716000.0 -0.05 -0.0481 -1.0 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K21 compound treatment 3.25936E7 1.74E7 1.17 1.1709 1.0 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K22 compound treatment 1.21568E7 -3000000.0 -0.2 -0.2015 -1.0 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K23 mock treatment 2.10538E7 5900000.0 0.4 0.3959 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 K24 mock treatment 1.82485E7 3090000.0 0.21 0.2076 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L01 compound treatment 1.0943E7 -4210000.0 -0.28 -0.283 -1.0 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L02 mock treatment 1.19953E7 -3160000.0 -0.21 -0.2124 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L03 compound treatment 1.88973E7 3740000.0 0.25 0.2511 1.0 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L04 mock treatment 1.8456E7 3300000.0 0.22 0.2215 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L05 compound treatment 2.18316E7 6670000.0 0.45 0.4482 1.0 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L06 mock treatment 3.18719E7 1.67E7 1.12 1.1224 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L07 mock treatment 3476980.0 -1.17E7 -0.78 -0.7844 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L08 mock treatment 1.45997E7 -558000.0 -0.04 -0.0375 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L09 compound treatment 9342450.0 -5820000.0 -0.39 -0.3905 -1.0 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L10 mock treatment 1.50999E7 -57900.0 0.0 -0.0039 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L11 compound treatment 2.47561E7 9600000.0 0.64 0.6446 1.0 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L12 mock treatment 1.67643E7 1610000.0 0.11 0.1079 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L13 compound treatment 2.03531E7 5200000.0 0.35 0.3489 1.0 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L14 mock treatment 2.17823E7 6620000.0 0.44 0.4449 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L15 mock treatment 1.99047E7 4750000.0 0.32 0.3188 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L16 mock treatment 1.37593E7 -1400000.0 -0.09 -0.0939 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L17 compound treatment 1.23212E7 -2840000.0 -0.19 -0.1905 -1.0 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L18 mock treatment 1.11979E7 -3960000.0 -0.27 -0.2659 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L19 compound treatment 1.66562E7 1500000.0 0.1 0.1006 1.0 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L20 mock treatment 1.35122E7 -1650000.0 -0.11 -0.1105 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L21 compound treatment 2.27873E7 7630000.0 0.51 0.5124 1.0 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L22 mock treatment 7760610.0 -7400000.0 -0.5 -0.4968 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L23 mock treatment 1.19253E7 -3230000.0 -0.22 -0.2171 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 L24 mock treatment 1.0583E7 -4570000.0 -0.31 -0.3072 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M01 compound treatment 1.13686E7 -3790000.0 -0.25 -0.2545 -1.0 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M02 compound treatment 1.25743E7 -2580000.0 -0.17 -0.1735 -1.0 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M03 compound treatment 1.13011E7 -3860000.0 -0.26 -0.259 -1.0 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M04 compound treatment 9672480.0 -5490000.0 -0.37 -0.3684 -1.0 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M05 compound treatment 3652900.0 -1.15E7 -0.77 -0.7726 -1.0 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M06 compound treatment 3.7974E7 2.28E7 1.53 1.5322 1.0 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M07 compound treatment 2.21293E7 6970000.0 0.47 0.4682 1.0 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M08 compound treatment 1.90916E7 3930000.0 0.26 0.2642 1.0 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M09 mock treatment 1.68854E7 1730000.0 0.12 0.116 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M10 mock treatment 1.61732E7 1020000.0 0.07 0.0682 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M11 compound treatment 4.95405E7 3.44E7 2.31 2.309 1.0 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M12 compound treatment 1.95017E7 4340000.0 0.29 0.2917 1.0 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M13 mock treatment 1.23152E7 -2840000.0 -0.19 -0.1909 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M14 mock treatment 1.89856E7 3830000.0 0.26 0.2571 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M15 compound treatment 1.10192E7 -4140000.0 -0.28 -0.2779 -1.0 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M16 compound treatment 6556260.0 -8600000.0 -0.58 -0.5776 -1.0 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M17 compound treatment 1.54685E7 311000.0 0.02 0.0209 1.0 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M18 compound treatment 5879810.0 -9280000.0 -0.62 -0.6231 -1.0 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M19 compound treatment 8264450.0 -6890000.0 -0.46 -0.4629 -1.0 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M20 compound treatment 2.45266E7 9370000.0 0.63 0.6292 1.0 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M21 compound treatment 3.6224E7 2.11E7 1.41 1.4147 1.0 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M22 compound treatment 1.99873E7 4830000.0 0.32 0.3243 1.0 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M23 compound treatment 1.94736E7 4320000.0 0.29 0.2898 1.0 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 M24 compound treatment 1.00636E7 -5090000.0 -0.34 -0.3421 -1.0 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N01 compound treatment 1.9581E7 4420000.0 0.3 0.297 1.0 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N02 mock treatment 2.51766E7 1.0E7 0.67 0.6728 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N03 compound treatment 1.60721E7 914000.0 0.06 0.0614 1.0 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N04 mock treatment 2.04074E7 5250000.0 0.35 0.3525 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N05 compound treatment 2.70572E7 1.19E7 0.8 0.7991 1.0 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N06 mock treatment 1.73092E7 2150000.0 0.14 0.1445 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N07 compound treatment 4841140.0 -1.03E7 -0.69 -0.6928 -1.0 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N08 mock treatment 1.56165E7 459000.0 0.03 0.0308 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N09 mock treatment 1.06548E7 -4500000.0 -0.3 -0.3024 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N10 mock treatment 9961380.0 -5200000.0 -0.35 -0.349 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N11 compound treatment 2210850.0 -1.29E7 -0.87 -0.8695 -1.0 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N12 mock treatment 2.33674E7 8210000.0 0.55 0.5513 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N13 mock treatment 8634690.0 -6520000.0 -0.44 -0.4381 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N14 mock treatment 1.98478E7 4690000.0 0.31 0.315 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N15 compound treatment 1.7148E7 1990000.0 0.13 0.1337 1.0 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N16 mock treatment 2.36013E7 8440000.0 0.57 0.567 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N17 compound treatment 2.18542E7 6700000.0 0.45 0.4497 1.0 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N18 mock treatment 1.95006E7 4340000.0 0.29 0.2916 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N19 compound treatment 9941630.0 -5220000.0 -0.35 -0.3503 -1.0 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N20 mock treatment 2.10248E7 5870000.0 0.39 0.394 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N21 compound treatment 2864620.0 -1.23E7 -0.83 -0.8256 -1.0 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N22 mock treatment 9009820.0 -6150000.0 -0.41 -0.4129 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N23 compound treatment 4514030.0 -1.06E7 -0.71 -0.7148 -1.0 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 N24 mock treatment 1.02034E7 -4950000.0 -0.33 -0.3327 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O01 compound treatment 1.57659E7 608000.0 0.04 0.0408 1.0 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O02 compound treatment 1.09197E7 -4240000.0 -0.28 -0.2846 -1.0 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O03 compound treatment 2.05567E7 5400000.0 0.36 0.3626 1.0 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O04 compound treatment 1.38027E7 -1360000.0 -0.09 -0.091 -1.0 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O05 compound treatment 1.21022E7 -3060000.0 -0.21 -0.2052 -1.0 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O06 compound treatment 3072860.0 -1.21E7 -0.81 -0.8116 -1.0 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O07 compound treatment 1.48807E7 -277000.0 -0.02 -0.0186 -1.0 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O08 compound treatment 4783120.0 -1.04E7 -0.7 -0.6967 -1.0 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O09 compound treatment 1.58826E7 725000.0 0.05 0.0487 1.0 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O10 compound treatment 3.31943E7 1.8E7 1.21 1.2113 1.0 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O11 mock treatment 7188480.0 -7970000.0 -0.54 -0.5352 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O12 mock treatment 5927550.0 -9230000.0 -0.62 -0.6199 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O13 compound treatment 1.98127E7 4650000.0 0.31 0.3126 1.0 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O14 compound treatment 1.68382E7 1680000.0 0.11 0.1128 1.0 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O15 compound treatment 2915620.0 -1.22E7 -0.82 -0.8221 -1.0 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O16 compound treatment 1.2685E7 -2470000.0 -0.17 -0.1661 -1.0 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O17 compound treatment 2.3974E7 8820000.0 0.59 0.5921 1.0 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O18 compound treatment 4430560.0 -1.07E7 -0.72 -0.7204 -1.0 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O19 compound treatment 1.38708E7 -1290000.0 -0.09 -0.0864 -1.0 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O20 compound treatment 1.63921E7 1230000.0 0.08 0.0829 1.0 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O21 compound treatment 1.33689E7 -1790000.0 -0.12 -0.1201 -1.0 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O22 compound treatment 2.65592E7 1.14E7 0.77 0.7657 1.0 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O23 compound treatment 3.11142E7 1.6E7 1.07 1.0716 1.0 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 O24 compound treatment 2.3977E7 8820000.0 0.59 0.5923 1.0 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P01 compound treatment 2.78059E7 1.26E7 0.85 0.8494 1.0 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P02 mock treatment 1.34093E7 -1750000.0 -0.12 -0.1174 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P03 compound treatment 1.31541E7 -2000000.0 -0.13 -0.1346 -1.0 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P04 mock treatment 1.8267E7 3110000.0 0.21 0.2088 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P05 compound treatment 1.4049E7 -1110000.0 -0.07 -0.0745 -1.0 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P06 mock treatment 1.79537E7 2800000.0 0.19 0.1878 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P07 compound treatment 1.77665E7 2610000.0 0.18 0.1752 1.0 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P08 mock treatment 5650000.0 -9510000.0 -0.64 -0.6385 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P09 compound treatment 1.67064E7 1550000.0 0.1 0.104 1.0 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P10 mock treatment 1.39482E7 -1210000.0 -0.08 -0.0812 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P11 mock treatment 1.14129E7 -3740000.0 -0.25 -0.2515 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P12 mock treatment 1.47128E7 -445000.0 -0.03 -0.0299 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P13 compound treatment 1751300.0 -1.34E7 -0.9 -0.9003 -1.0 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P14 mock treatment 9742830.0 -5410000.0 -0.36 -0.3636 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P15 compound treatment 5309040.0 -9850000.0 -0.66 -0.6614 -1.0 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P16 mock treatment 1.30225E7 -2140000.0 -0.14 -0.1434 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P17 compound treatment 1.36889E7 -1470000.0 -0.1 -0.0986 -1.0 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P18 mock treatment 1.38174E7 -1340000.0 -0.09 -0.09 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P19 compound treatment 1.19382E7 -3220000.0 -0.22 -0.2162 -1.0 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P20 mock treatment 2.23379E7 7180000.0 0.48 0.4822 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P21 compound treatment 1.53722E7 214000.0 0.01 0.0144 1.0 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P22 mock treatment 8067420.0 -7090000.0 -0.48 -0.4762 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P23 compound treatment 8102880.0 -7050000.0 -0.47 -0.4738 -1.0 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2283 P24 mock treatment 4.0208E7 2.51E7 1.68 1.6823 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A01 mock treatment 1.03126E7 -4860000.0 -0.33 -0.3266 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A02 compound treatment 2.80776E7 1.29E7 0.87 0.8664 1.0 3555546 CMLD3_000001 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A03 mock treatment 1.58939E7 717000.0 0.05 0.0482 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A04 compound treatment 2766240.0 -1.24E7 -0.83 -0.8334 -1.0 3555566 CMLD3_000002 COc1ccc2C(=O)[C@@H](OC(=O)NCCOc3ccccc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A05 compound treatment 2.69217E7 1.17E7 0.79 0.7888 1.0 3555570 CMLD3_000003 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A06 compound treatment 1.43253E7 -851000.0 -0.06 -0.0572 -1.0 3555574 CMLD3_000004 COc1ccc2O[C@H]([C@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A07 mock treatment 1.4736E7 -440000.0 -0.03 -0.0296 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A08 compound treatment 1.38795E7 -1300000.0 -0.09 -0.0871 -1.0 3555579 CMLD3_000005 COc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A09 compound treatment 1.09048E7 -4270000.0 -0.29 -0.2869 -1.0 3555584 CMLD3_000006 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A10 compound treatment 7601490.0 -7570000.0 -0.51 -0.5087 -1.0 3555589 CMLD3_000007 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A11 mock treatment 5118540.0 -1.01E7 -0.68 -0.6754 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A12 compound treatment 5046960.0 -1.01E7 -0.68 -0.6803 -1.0 3555594 CMLD3_000008 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A13 mock treatment 1.13902E7 -3790000.0 -0.25 -0.2543 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A14 mock treatment 1.40458E7 -1130000.0 -0.08 -0.0759 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A15 compound treatment 4205650.0 -1.1E7 -0.74 -0.7368 -1.0 3555598 CMLD3_000009 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2cc(C)cc(C)c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A16 compound treatment 1.94333E7 4260000.0 0.29 0.2859 1.0 3555600 CMLD3_000010 Cc1cc(C)cc(/C=C/[C@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A17 compound treatment 1.17503E7 -3430000.0 -0.23 -0.2301 -1.0 3555605 CMLD3_000011 COc1ccc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3cc(C)cc(C)c3)C=C2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A18 compound treatment 1.05526E8 9.03E7 6.07 6.0675 1.0 3555609 CMLD3_000012 CC(C)(C)OC(=O)C1=NOC2(C1)C=CC(=O)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A19 compound treatment 1.11465E7 -4030000.0 -0.27 -0.2706 -1.0 3555611 CMLD3_000013 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A20 compound treatment 2.56868E7 1.05E7 0.71 0.7058 1.0 3555615 CMLD3_000014 CCCCCCCC#Cc1ccccc1C(NC(=O)OC)C(C(=O)OC)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A21 compound treatment 1.12719E7 -3900000.0 -0.26 -0.2622 -1.0 3555617 CMLD3_000015 CC(C)(C)OC1C2C3C2C4C1C3CC=CC4(O)CC=C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A22 compound treatment 2794660.0 -1.24E7 -0.83 -0.8315 -1.0 3555619 CMLD3_000016 COCn1c2ccccc2c3nnc(nc13)C(=O)O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A23 compound treatment 2.16422E7 6470000.0 0.43 0.4342 1.0 3555621 CMLD3_000017 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2cccs2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 A24 compound treatment 1.45776E7 -599000.0 -0.04 -0.0402 -1.0 3555626 CMLD3_000018 CC(=CCC/C(=C/C=C/C1=CC2(C)CC1(C)C(CC2=O)\C=C(/C)\CCC=C(C)C)/C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B01 compound treatment 1730180.0 -1.34E7 -0.9 -0.903 -1.0 3555630 CMLD3_000019 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B02 compound treatment 1.51238E7 -52700.0 0.0 -0.0035 -1.0 3555635 CMLD3_000020 COc1ccc2C(=O)[C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B03 compound treatment 1.59839E7 807000.0 0.05 0.0542 1.0 3555639 CMLD3_000021 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B04 compound treatment 7444940.0 -7730000.0 -0.52 -0.5192 -1.0 3555643 CMLD3_000022 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B05 compound treatment 1.18592E7 -3320000.0 -0.22 -0.2228 -1.0 3555647 CMLD3_000023 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B06 compound treatment 9270700.0 -5910000.0 -0.4 -0.3966 -1.0 3555651 CMLD3_000024 COc1ccc2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B07 compound treatment 4.52932E7 3.01E7 2.02 2.0225 1.0 3555653 CMLD3_000025 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B08 compound treatment 2.691E7 1.17E7 0.79 0.788 1.0 3555657 CMLD3_000026 COc1ccc2C(=O)[C@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@H](Oc2c1)c5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B09 compound treatment 7215380.0 -7960000.0 -0.53 -0.5346 -1.0 3555659 CMLD3_000027 COc1ccc2C(=O)[C@H](OC(=O)N[C@H](C)C3CCCCC3)[C@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B10 compound treatment 1.48057E7 -371000.0 -0.02 -0.0249 -1.0 3555663 CMLD3_000028 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B11 compound treatment 2.46552E7 9480000.0 0.64 0.6366 1.0 3555666 CMLD3_000029 COc1ccc2O[C@H]([C@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B12 compound treatment 6813790.0 -8360000.0 -0.56 -0.5616 -1.0 3555670 CMLD3_000030 COc1ccc2C(=O)[C@H](OC(=O)NCCOc3ccccc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B13 mock treatment 1.57305E7 554000.0 0.04 0.0372 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B14 mock treatment 7704540.0 -7470000.0 -0.5 -0.5018 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B15 compound treatment 4117980.0 -1.11E7 -0.74 -0.7426 -1.0 3555672 CMLD3_000031 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)c4ccccc4)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B16 compound treatment 1.94076E7 4230000.0 0.28 0.2841 1.0 3555676 CMLD3_000032 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B17 compound treatment 3.39947E7 1.88E7 1.26 1.2637 1.0 3555680 CMLD3_000033 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B18 compound treatment 1.4963E7 -213000.0 -0.01 -0.0143 -1.0 3555686 CMLD3_000034 COc1ccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccc(OC)cc4)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B19 compound treatment 1.79257E7 2750000.0 0.18 0.1846 1.0 3555689 CMLD3_000035 COC(=O)N[C@H](CC(=O)C)c1ccc2OCOc2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B20 mock treatment 2.51319E7 9960000.0 0.67 0.6686 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B21 compound treatment 1.79265E7 2750000.0 0.18 0.1847 1.0 3555694 CMLD3_000036 COCO[C@@H]1[C@@H](C)C(=O)N2[C@@H]1[C@@H](Oc3ccc(OC)cc23)/C=C/C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B22 compound treatment 8310510.0 -6870000.0 -0.46 -0.4611 -1.0 3555700 CMLD3_000037 C[C@@H]1C=CCCO[C@H]1c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B23 compound treatment 9928560.0 -5250000.0 -0.35 -0.3524 -1.0 3555703 CMLD3_000038 CCCCCCCC#Cc1ccccc1/C=N/S(=O)c2ccc(C)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 B24 compound treatment 1.66448E7 1470000.0 0.1 0.0986 1.0 3555707 CMLD3_000039 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)c3ccccn3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C01 compound treatment 1.96279E7 4450000.0 0.3 0.2989 1.0 3555711 CMLD3_000040 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3[C@H](O)[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C02 compound treatment 2.00717E7 4900000.0 0.33 0.3287 1.0 3555810 CMLD3_000041 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C03 compound treatment 4005360.0 -1.12E7 -0.75 -0.7502 -1.0 3555814 CMLD3_000042 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C04 compound treatment 1.37835E7 -1390000.0 -0.09 -0.0935 -1.0 3555817 CMLD3_000043 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C05 compound treatment 1.03035E7 -4870000.0 -0.33 -0.3272 -1.0 3555820 CMLD3_000044 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C06 compound treatment 2.12707E7 6090000.0 0.41 0.4093 1.0 3555823 CMLD3_000045 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C07 compound treatment 7500770.0 -7680000.0 -0.52 -0.5155 -1.0 3555825 CMLD3_000046 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C08 compound treatment 9597300.0 -5580000.0 -0.37 -0.3747 -1.0 3555829 CMLD3_000047 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C09 compound treatment 1.26719E7 -2500000.0 -0.17 -0.1682 -1.0 3555833 CMLD3_000048 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C10 compound treatment 1.61019E7 925000.0 0.06 0.0621 1.0 3555837 CMLD3_000049 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C11 mock treatment 2.11682E7 5990000.0 0.4 0.4024 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C12 mock treatment 1.42681E7 -908000.0 -0.06 -0.061 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C13 compound treatment 1.50787E7 -97800.0 -0.01 -0.0066 -1.0 3555841 CMLD3_000050 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2Cc3cc(OC)ccc3O[C@H]2c4cccc(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C14 compound treatment 7352700.0 -7820000.0 -0.53 -0.5254 -1.0 3555844 CMLD3_000051 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc(Cl)cc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C15 mock treatment 8239360.0 -6940000.0 -0.47 -0.4659 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C16 mock treatment 3.18595E7 1.67E7 1.12 1.1204 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C17 compound treatment 3.37817E7 1.86E7 1.25 1.2494 1.0 3555848 CMLD3_000052 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2cccc(c2)N(C)C)C#Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C18 compound treatment 1.05871E7 -4590000.0 -0.31 -0.3082 -1.0 3555853 CMLD3_000053 COC(=O)C1(CC2(CCC3C4C5C41)OCCO2)C3C5OCc6ccccc6 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C19 compound treatment 1.7004E7 1830000.0 0.12 0.1227 1.0 3555855 CMLD3_000054 COc1cccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4cccc(OC)c4)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C20 compound treatment 1.3772E7 -1400000.0 -0.09 -0.0943 -1.0 3555859 CMLD3_000055 COC(=O)[C@@H]1[C@H]([C@H]2C(=O)c3c(OC)cc(OC)cc3O[C@@]12c4ccc(OC)cc4)c5ccccc5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C21 compound treatment 5.01952E7 3.5E7 2.35 2.3517 1.0 831758 CMLD3_000056 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C22 compound treatment 8920260.0 -6260000.0 -0.42 -0.4201 -1.0 3555865 CMLD3_000057 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(C)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C23 compound treatment 1.10763E7 -4100000.0 -0.28 -0.2753 -1.0 3555869 CMLD3_000058 COC(=O)N[C@H](CC(=O)C)c1ccc(F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 C24 compound treatment 7429810.0 -7750000.0 -0.52 -0.5202 -1.0 3555873 CMLD3_000059 CCCCCCCC1=CC2=CC(=O)C(C)(O)C(=O)C2=CN1CCCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D01 compound treatment 1.34115E8 1.19E8 7.99 7.9874 1.0 3555876 CMLD3_000060 Cc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D02 compound treatment 1.36481E7 -1530000.0 -0.1 -0.1026 -1.0 3555884 CMLD3_000061 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D03 compound treatment 1.96489E7 4470000.0 0.3 0.3003 1.0 3555888 CMLD3_000062 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D04 mock treatment 1.14089E7 -3770000.0 -0.25 -0.253 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D05 compound treatment 1.37092E7 -1470000.0 -0.1 -0.0985 -1.0 3555892 CMLD3_000063 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D06 compound treatment 1.37578E7 -1420000.0 -0.1 -0.0953 -1.0 3555896 CMLD3_000064 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D07 compound treatment 7870800.0 -7310000.0 -0.49 -0.4906 -1.0 3555901 CMLD3_000065 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D08 mock treatment 8725330.0 -6450000.0 -0.43 -0.4332 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D09 compound treatment 1.05402E7 -4640000.0 -0.31 -0.3113 -1.0 3555905 CMLD3_000066 COc1cc(NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4)cc(OC)c1OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D10 compound treatment 2.66966E7 1.15E7 0.77 0.7736 1.0 3555908 CMLD3_000067 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D11 mock treatment 2.43905E7 9210000.0 0.62 0.6188 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D12 mock treatment 2.78231E7 1.26E7 0.85 0.8493 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D13 mock treatment 1.35748E7 -1600000.0 -0.11 -0.1076 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D14 compound treatment 1.44645E7 -712000.0 -0.05 -0.0478 -1.0 3555912 CMLD3_000068 CN(C)c1cccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D15 mock treatment 9558320.0 -5620000.0 -0.38 -0.3773 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D16 mock treatment 1.54327E7 256000.0 0.02 0.0172 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D17 compound treatment 2.59305E7 1.08E7 0.72 0.7222 1.0 3555916 CMLD3_000069 OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C=O)cc2)C#Cc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D18 compound treatment 8299060.0 -6880000.0 -0.46 -0.4619 -1.0 3555921 CMLD3_000070 COc1ccccc1/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccccc4OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D19 compound treatment 7730370.0 -7450000.0 -0.5 -0.5 -1.0 3555925 CMLD3_000071 CCC/C=C/C1C(CO)C2(OCC(CC)(CC)CO2)[C@@H]3O[C@@H]3C1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D20 compound treatment 1.99478E7 4770000.0 0.32 0.3204 1.0 3555929 CMLD3_000072 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C(F)(F)F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D21 compound treatment 2.00291E7 4850000.0 0.33 0.3259 1.0 3555933 CMLD3_000073 COc1ccc(cc1)C(=O)CC(=O)c2c(O)cc(OC)cc2OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D22 compound treatment 8602340.0 -6570000.0 -0.44 -0.4415 -1.0 3555935 CMLD3_000074 COC(=O)N[C@@H](c1ccco1)[C@@]2(CCCC2=O)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D23 mock treatment 7439780.0 -7740000.0 -0.52 -0.5196 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 D24 compound treatment 1.50309E7 -146000.0 -0.01 -0.0098 -1.0 3555939 CMLD3_000075 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(F)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E01 mock treatment 1.7174E7 2000000.0 0.13 0.1341 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E02 mock treatment 4.03636E7 2.52E7 1.69 1.6915 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E03 mock treatment 1.38017E7 -1370000.0 -0.09 -0.0923 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E04 compound treatment 1.21341E7 -3040000.0 -0.2 -0.2043 -1.0 3555943 CMLD3_000076 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E05 compound treatment 1.04018E7 -4770000.0 -0.32 -0.3206 -1.0 3555945 CMLD3_000077 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E06 compound treatment 7768260.0 -7410000.0 -0.5 -0.4975 -1.0 3555948 CMLD3_000078 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E07 compound treatment 2.97691E7 1.46E7 0.98 0.98 1.0 3555952 CMLD3_000079 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E08 compound treatment 2.16928E7 6520000.0 0.44 0.4376 1.0 3555954 CMLD3_000080 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E09 mock treatment 7146210.0 -8030000.0 -0.54 -0.5393 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E10 mock treatment 2.06542E7 5480000.0 0.37 0.3679 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E11 compound treatment 9778450.0 -5400000.0 -0.36 -0.3625 -1.0 3555958 CMLD3_000081 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E12 compound treatment 3696080.0 -1.15E7 -0.77 -0.771 -1.0 3555962 CMLD3_000082 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E13 compound treatment 2.04942E7 5320000.0 0.36 0.3571 1.0 3555964 CMLD3_000083 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E14 compound treatment 1.22084E7 -2970000.0 -0.2 -0.1993 -1.0 3555968 CMLD3_000084 CCOC(=O)OC[C@H]1O[C@H](CCc2ccccc2)CC[C@@H]1Oc3ccc(OC)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E15 compound treatment 1.19208E7 -3260000.0 -0.22 -0.2186 -1.0 3555972 CMLD3_000085 CC(C)(C)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E16 compound treatment 2.48713E7 9690000.0 0.65 0.6511 1.0 3555975 CMLD3_000086 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccccc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E17 mock treatment 7775710.0 -7400000.0 -0.5 -0.497 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E18 mock treatment 6099820.0 -9080000.0 -0.61 -0.6095 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E19 compound treatment 1.44685E7 -708000.0 -0.05 -0.0475 -1.0 3555978 CMLD3_000087 C[C@H](O)CCCCCCC/C=C/C=C/C(=O)N 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E20 compound treatment 1.19366E7 -3240000.0 -0.22 -0.2176 -1.0 3555982 CMLD3_000088 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cccc3c4ccccc4oc23)c5cccc6c7ccccc7oc56)C(O)(c8cccc9c%10ccccc%10oc89)c%11cccc%12c%13ccccc%13oc%11%12 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E21 mock treatment 3.01692E7 1.5E7 1.01 1.0068 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E22 compound treatment 8369090.0 -6810000.0 -0.46 -0.4572 -1.0 3555987 CMLD3_000089 COC(=O)N[C@@H](c1cccc(C)c1)[C@@]2(CCCC2=O)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E23 compound treatment 4.37444E7 2.86E7 1.92 1.9185 1.0 3555990 CMLD3_000090 CC1(CC2(C)C(CC1=O)c3ccc(cc3)C(F)(F)F)C=C2/C=C/c4ccc(cc4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 E24 mock treatment 2.64664E7 1.13E7 0.76 0.7582 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F01 mock treatment 6887650.0 -8290000.0 -0.56 -0.5566 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F02 mock treatment 8500930.0 -6680000.0 -0.45 -0.4483 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F03 compound treatment 4438380.0 -1.07E7 -0.72 -0.7211 -1.0 3555993 CMLD3_000091 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F04 compound treatment 1.41343E7 -1040000.0 -0.07 -0.07 -1.0 3555995 CMLD3_000092 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F05 compound treatment 2.98604E7 1.47E7 0.99 0.9861 1.0 3555997 CMLD3_000093 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F06 mock treatment 4870510.0 -1.03E7 -0.69 -0.6921 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F07 compound treatment 2.56565E7 1.05E7 0.7 0.7038 1.0 3555999 CMLD3_000094 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F08 compound treatment 1.00939E7 -5080000.0 -0.34 -0.3413 -1.0 3556000 CMLD3_000095 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H]3CCCc4ccccc34)C(=O)c2c1)c5ccc(OC)c(Br)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F09 mock treatment 2.40959E7 8920000.0 0.6 0.599 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F10 mock treatment 2.12751E7 6100000.0 0.41 0.4096 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F11 mock treatment 6647860.0 -8530000.0 -0.57 -0.5727 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F12 compound treatment 3.5248E7 2.01E7 1.35 1.3479 1.0 3556002 CMLD3_000096 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F13 compound treatment 1.42845E7 -892000.0 -0.06 -0.0599 -1.0 3556004 CMLD3_000097 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F14 compound treatment 1.06195E8 9.1E7 6.11 6.1124 1.0 3556006 CMLD3_000098 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(Br)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F15 compound treatment 2.17356E7 6560000.0 0.44 0.4405 1.0 3556008 CMLD3_000099 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F16 compound treatment 6383840.0 -8790000.0 -0.59 -0.5905 -1.0 3556010 CMLD3_000100 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F17 mock treatment 1.48482E7 -328000.0 -0.02 -0.022 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F18 mock treatment 2.5707E7 1.05E7 0.71 0.7072 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F19 compound treatment 1.83542E7 3180000.0 0.21 0.2134 1.0 3556012 CMLD3_000101 COc1ccccc1/C=C/C(O)C(=C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F20 compound treatment 6672580.0 -8500000.0 -0.57 -0.5711 -1.0 3556014 CMLD3_000102 COCn1c2ccccc2c3nnc(nc13)C(=O)OC(C)C#C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F21 compound treatment 1.5731E7 555000.0 0.04 0.0372 1.0 3556015 CMLD3_000103 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C3(CCCC3=O)C(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F22 compound treatment 1.50293E7 -147000.0 -0.01 -0.0099 -1.0 1952239 CMLD3_000104 O=C1/C(=C/c2ccccc2)/Oc3ccccc13 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F23 compound treatment 1.99495E7 4770000.0 0.32 0.3205 1.0 3556016 CMLD3_000105 Cc1c2OCOc2ccc1O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 F24 compound treatment 1.6692E7 1520000.0 0.1 0.1018 1.0 3556017 CMLD3_000106 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1ccc2ccccc2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G01 compound treatment 4430240.0 -1.07E7 -0.72 -0.7217 -1.0 3556019 CMLD3_000107 COc1ccc2O[C@H]([C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G02 mock treatment 2.3456E7 8280000.0 0.56 0.556 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G03 mock treatment 1.17586E7 -3420000.0 -0.23 -0.2295 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G04 mock treatment 1.54033E7 227000.0 0.02 0.0152 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G05 compound treatment 1.44398E7 -737000.0 -0.05 -0.0495 -1.0 3556020 CMLD3_000108 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G06 compound treatment 8552160.0 -6620000.0 -0.44 -0.4449 -1.0 3556022 CMLD3_000109 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G07 compound treatment 1.46711E7 -505000.0 -0.03 -0.0339 -1.0 3556024 CMLD3_000110 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G08 mock treatment 1.43844E7 -792000.0 -0.05 -0.0532 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G09 compound treatment 5490290.0 -9690000.0 -0.65 -0.6505 -1.0 3556025 CMLD3_000111 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G10 compound treatment 3.0696E7 1.55E7 1.04 1.0422 1.0 3556027 CMLD3_000112 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G11 mock treatment 1.08452E8 9.33E7 6.26 6.264 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G12 compound treatment 2.33939E7 8220000.0 0.55 0.5518 1.0 3556029 CMLD3_000113 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G13 compound treatment 2.6987E7 1.18E7 0.79 0.7931 1.0 3556031 CMLD3_000114 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(OC)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G14 compound treatment 2.82199E7 1.3E7 0.88 0.8759 1.0 3556033 CMLD3_000115 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)c(c1)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G15 compound treatment 1.17099E7 -3470000.0 -0.23 -0.2328 -1.0 3556035 CMLD3_000116 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(cc3)C(C)(C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G16 compound treatment 2.13158E7 6140000.0 0.41 0.4123 1.0 3556037 CMLD3_000117 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G17 mock treatment 1.50313E7 -145000.0 -0.01 -0.0097 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G18 compound treatment 1.20771E7 -3100000.0 -0.21 -0.2081 -1.0 3556038 CMLD3_000118 CC(=C)C(O)/C=C/C=C/c1ccccc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G19 mock treatment 1.98464E7 4670000.0 0.31 0.3136 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G20 mock treatment 2.06166E7 5440000.0 0.37 0.3653 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G21 compound treatment 7832580.0 -7340000.0 -0.49 -0.4932 -1.0 3556040 CMLD3_000119 COC(=O)N[C@H](CC(=O)C)c1ccc(Cl)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G22 compound treatment 1.20801E7 -3100000.0 -0.21 -0.2079 -1.0 3556042 CMLD3_000120 CCCCCCCC1=CC2=CC(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCc3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G23 compound treatment 3028640.0 -1.21E7 -0.82 -0.8158 -1.0 3556043 CMLD3_000121 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1C=C(C(=O)OCC)C(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 G24 compound treatment 1.65468E7 1370000.0 0.09 0.092 1.0 3556044 CMLD3_000122 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1/C=C(/C(=O)C)\C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H01 compound treatment 1.61844E7 1010000.0 0.07 0.0677 1.0 3556046 CMLD3_000123 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H02 compound treatment 5620380.0 -9560000.0 -0.64 -0.6417 -1.0 3556048 CMLD3_000124 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H03 mock treatment 5375170.0 -9800000.0 -0.66 -0.6582 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H04 mock treatment 9033010.0 -6140000.0 -0.41 -0.4126 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H05 compound treatment 2.45608E7 9380000.0 0.63 0.6302 1.0 3556050 CMLD3_000125 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H06 compound treatment 2.07306E7 5550000.0 0.37 0.373 1.0 3556052 CMLD3_000126 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H07 compound treatment 1.99133E7 4740000.0 0.32 0.3181 1.0 3556054 CMLD3_000127 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H08 compound treatment 7639220.0 -7540000.0 -0.51 -0.5062 -1.0 3556056 CMLD3_000128 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H09 compound treatment 1.06048E7 -4570000.0 -0.31 -0.307 -1.0 3556058 CMLD3_000129 Brc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H10 compound treatment 1.22341E8 1.07E8 7.2 7.1967 1.0 3556060 CMLD3_000130 Fc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H11 compound treatment 1.16017E7 -3570000.0 -0.24 -0.2401 -1.0 3556062 CMLD3_000131 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H12 compound treatment 1.8948E7 3770000.0 0.25 0.2533 1.0 3556064 CMLD3_000132 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H13 mock treatment 5658590.0 -9520000.0 -0.64 -0.6392 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H14 compound treatment 2.01363E8 1.86E8 12.5 12.5035 1.0 3556065 CMLD3_000133 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(cc2)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H15 compound treatment 2.20972E7 6920000.0 0.46 0.4648 1.0 3556067 CMLD3_000134 Cc1cc(C)cc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)C4CCCC4)C=C2)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H16 compound treatment 1.02618E7 -4910000.0 -0.33 -0.33 -1.0 3556069 CMLD3_000135 Cc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H17 compound treatment 1.09484E7 -4230000.0 -0.28 -0.2839 -1.0 3556071 CMLD3_000136 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(F)cc3C)C=C2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H18 compound treatment 3285900.0 -1.19E7 -0.8 -0.7985 -1.0 3556073 CMLD3_000137 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H19 mock treatment 1.84707E7 3290000.0 0.22 0.2212 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H20 mock treatment 2.13212E7 6140000.0 0.41 0.4127 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H21 compound treatment 1.95252E7 4350000.0 0.29 0.292 1.0 3556074 CMLD3_000138 CCCc1cc2C(=O)[C@H]3O[C@H]3[C@H](O)c2c(=O)o1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H22 compound treatment 5366700.0 -9810000.0 -0.66 -0.6588 -1.0 3556076 CMLD3_000139 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc2ccccc2c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H23 mock treatment 1.37419E7 -1430000.0 -0.1 -0.0963 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 H24 compound treatment 1.45015E7 -675000.0 -0.05 -0.0453 -1.0 3556078 CMLD3_000140 COC(=O)N[C@@H](c1cccc(F)c1)[C@@]2(CCCC2=O)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I01 compound treatment 1.80022E7 2830000.0 0.19 0.1898 1.0 3556080 CMLD3_000141 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I02 compound treatment 1.07325E7 -4440000.0 -0.3 -0.2984 -1.0 3556082 CMLD3_000142 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I03 compound treatment 1.20668E7 -3110000.0 -0.21 -0.2088 -1.0 3555962 CMLD3_000143 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I04 mock treatment 1.6065E7 889000.0 0.06 0.0597 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I05 mock treatment 2.62228E7 1.1E7 0.74 0.7418 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I06 mock treatment 1.57466E7 570000.0 0.04 0.0383 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I07 compound treatment 4777580.0 -1.04E7 -0.7 -0.6983 -1.0 3556084 CMLD3_000144 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I08 compound treatment 1.24454E7 -2730000.0 -0.18 -0.1834 -1.0 3556086 CMLD3_000145 Brc1ccc2O[C@H]([C@H](OC(=O)NC3CCCC3)C(=O)c2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I09 compound treatment 2.17857E7 6610000.0 0.44 0.4438 1.0 3556088 CMLD3_000146 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I10 compound treatment 9965710.0 -5210000.0 -0.35 -0.3499 -1.0 3556090 CMLD3_000147 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I11 compound treatment 4475700.0 -1.07E7 -0.72 -0.7186 -1.0 3556092 CMLD3_000148 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I12 compound treatment 1.94535E7 4280000.0 0.29 0.2872 1.0 3556094 CMLD3_000149 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I13 compound treatment 0.0 -1.52E7 -1.02 -1.0192 -1.0 3011535 CMLD3_000150 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I14 compound treatment 2.50074E8 2.35E8 15.77 15.7747 1.0 3556096 CMLD3_000151 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(C)cc2C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I15 compound treatment 2373760.0 -1.28E7 -0.86 -0.8598 -1.0 3556098 CMLD3_000152 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(cc2)c3ccccc3)c4ccc(cc4)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I16 compound treatment 1.67217E7 1550000.0 0.1 0.1038 1.0 3556100 CMLD3_000153 Cc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I17 compound treatment 9465010.0 -5710000.0 -0.38 -0.3836 -1.0 3556101 CMLD3_000154 Cc1cc(F)ccc1O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I18 compound treatment 5385040.0 -9790000.0 -0.66 -0.6575 -1.0 3556103 CMLD3_000155 COC(=O)N(CCc1ccc(OC)c(OC)c1)/C=C/c2ccc(OC)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I19 compound treatment 5095500.0 -1.01E7 -0.68 -0.677 -1.0 3556105 CMLD3_000156 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I20 compound treatment 5501090.0 -9680000.0 -0.65 -0.6498 -1.0 3556106 CMLD3_000157 CC(C)(C)OC1C2C3C2C(CC(O)CC=C)C1C3CC(O)CC=C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I21 mock treatment 1.57094E7 533000.0 0.04 0.0358 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I22 mock treatment 1.59574E7 781000.0 0.05 0.0524 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I23 compound treatment 9647420.0 -5530000.0 -0.37 -0.3713 -1.0 2119115 CMLD3_000158 COc1ccc(/C=C/C(=O)c2ccc(OC)cc2O)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 I24 compound treatment 1.14222E7 -3750000.0 -0.25 -0.2521 -1.0 3556107 CMLD3_000159 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc(Cl)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J01 compound treatment 1.41089E7 -1070000.0 -0.07 -0.0717 -1.0 3556109 CMLD3_000160 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J02 compound treatment 1.0788E7 -4390000.0 -0.29 -0.2947 -1.0 3556112 CMLD3_000161 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J03 compound treatment 1.61804E7 1000000.0 0.07 0.0674 1.0 3556115 CMLD3_000162 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4cccc(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J04 mock treatment 2.18717E7 6700000.0 0.45 0.4496 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J05 mock treatment 1902820.0 -1.33E7 -0.89 -0.8914 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J06 mock treatment 1.85724E7 3400000.0 0.23 0.2281 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J07 compound treatment 9218690.0 -5960000.0 -0.4 -0.4001 -1.0 3556117 CMLD3_000163 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J08 compound treatment 1.12994E7 -3880000.0 -0.26 -0.2604 -1.0 3556119 CMLD3_000164 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J09 compound treatment 1.57316E7 555000.0 0.04 0.0373 1.0 3556123 CMLD3_000165 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J10 compound treatment 1.60762E7 900000.0 0.06 0.0604 1.0 3556129 CMLD3_000166 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J11 compound treatment 2.58673E7 1.07E7 0.72 0.7179 1.0 3556130 CMLD3_000167 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J12 compound treatment 2.19975E7 6820000.0 0.46 0.4581 1.0 3556132 CMLD3_000168 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J13 compound treatment 1142220.0 -1.4E7 -0.94 -0.9425 -1.0 3556134 CMLD3_000169 COCOc1ccc(OC)cc1C(=O)/C=C/c2ccc(OC)c(Br)c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J14 compound treatment 1.6227E7 1050000.0 0.07 0.0706 1.0 3556136 CMLD3_000170 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(F)cc2F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J15 compound treatment 1806290.0 -1.34E7 -0.9 -0.8979 -1.0 3556138 CMLD3_000171 CCOC(=O)OC[C@H]1O[C@@H]([C@@H](C=C1)c2cc(ccc2O)c3ccccc3)c4ccc(cc4)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J16 mock treatment 1.25469E7 -2630000.0 -0.18 -0.1766 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J17 compound treatment 4071710.0 -1.11E7 -0.75 -0.7457 -1.0 3556140 CMLD3_000172 COC(=O)C1(CC(=CCc2ccccc2C1C[N+](=O)[O-])C=C)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J18 mock treatment 9712190.0 -5460000.0 -0.37 -0.367 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J19 compound treatment 3.19334E7 1.68E7 1.13 1.1253 1.0 3556141 CMLD3_000173 COc1cccc(/C=C/C(O)C(=C)C)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J20 compound treatment 2.65025E7 1.13E7 0.76 0.7606 1.0 3556143 CMLD3_000174 COC(=O)N1CCc2cc(OC)c(OC)cc2C1Cc3ccc(OC)cc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J21 mock treatment 1.76557E7 2480000.0 0.17 0.1665 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J22 mock treatment 3.80369E7 2.29E7 1.54 1.5352 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J23 compound treatment 1.98668E7 4690000.0 0.31 0.315 1.0 3556144 CMLD3_000175 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)c2cccc(C)c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 J24 compound treatment 2.07176E7 5540000.0 0.37 0.3721 1.0 3556146 CMLD3_000176 OC[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K01 compound treatment 1.84961E7 3320000.0 0.22 0.2229 1.0 3556148 CMLD3_000177 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K02 compound treatment 2.35909E7 8410000.0 0.57 0.5651 1.0 3556150 CMLD3_000178 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K03 compound treatment 1.24507E7 -2730000.0 -0.18 -0.183 -1.0 3556152 CMLD3_000179 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K04 mock treatment 1.92153E7 4040000.0 0.27 0.2712 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K05 compound treatment 4937820.0 -1.02E7 -0.69 -0.6876 -1.0 3011485 CMLD3_000180 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K06 compound treatment 1.19006E7 -3280000.0 -0.22 -0.22 -1.0 3556154 CMLD3_000181 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K07 mock treatment 9224910.0 -5950000.0 -0.4 -0.3997 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K08 mock treatment 1.68989E7 1720000.0 0.12 0.1157 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K09 compound treatment 2.05066E7 5330000.0 0.36 0.3579 1.0 3556156 CMLD3_000182 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K10 compound treatment 2.90525E7 1.39E7 0.93 0.9319 1.0 3556158 CMLD3_000183 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K11 compound treatment 2.62051E7 1.1E7 0.74 0.7406 1.0 3556159 CMLD3_000184 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K12 compound treatment 2.3976E7 8800000.0 0.59 0.5909 1.0 3556161 CMLD3_000185 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K13 mock treatment 3177810.0 -1.2E7 -0.81 -0.8058 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K14 compound treatment 3.75717E7 2.24E7 1.5 1.504 1.0 3556162 CMLD3_000186 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)c2cc(C)cc(C)c2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K15 mock treatment 1.81021E7 2930000.0 0.2 0.1965 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K16 mock treatment 2.29482E7 7770000.0 0.52 0.5219 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K17 compound treatment 2.73414E7 1.22E7 0.82 0.8169 1.0 3556164 CMLD3_000187 COC(=O)N[C@H](CC(=O)C)c1cccc(C)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K18 compound treatment 3.44972E7 1.93E7 1.3 1.2975 1.0 3556166 CMLD3_000188 COC(=O)N[C@H](CC(=O)C)c1ccco1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K19 compound treatment 1.21118E7 -3060000.0 -0.21 -0.2058 -1.0 3556168 CMLD3_000189 COc1ccc(OC)c(c1)[C@@H]2OCCC=C[C@H]2C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K20 compound treatment 2.28204E7 7640000.0 0.51 0.5133 1.0 3556170 CMLD3_000190 CC1=C(C)CC(C(C1)C(=O)c2ccccc2O)c3ccccc3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K21 mock treatment 1.54781E7 302000.0 0.02 0.0203 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K22 compound treatment 1.77572E7 2580000.0 0.17 0.1733 1.0 3556171 CMLD3_000191 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K23 mock treatment 1.88855E7 3710000.0 0.25 0.2491 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 K24 mock treatment 2174580.0 -1.3E7 -0.87 -0.8731 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L01 mock treatment 1.54712E7 295000.0 0.02 0.0198 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L02 compound treatment 1.5283E7 107000.0 0.01 0.0072 1.0 3556172 CMLD3_000192 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L03 mock treatment 2.60749E7 1.09E7 0.73 0.7319 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L04 mock treatment 1.60414E7 865000.0 0.06 0.0581 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L05 compound treatment 7.39942E7 5.88E7 3.95 3.9499 1.0 3556173 CMLD3_000193 O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L06 compound treatment 1.86628E7 3490000.0 0.23 0.2341 1.0 3556175 CMLD3_000194 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L07 mock treatment 1.65403E7 1360000.0 0.09 0.0916 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L08 mock treatment 1.86285E7 3450000.0 0.23 0.2318 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L09 compound treatment 2.40005E7 8820000.0 0.59 0.5926 1.0 3556177 CMLD3_000195 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L10 compound treatment 1.89039E7 3730000.0 0.25 0.2503 1.0 3556179 CMLD3_000196 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L11 compound treatment 1.3993E7 -1180000.0 -0.08 -0.0795 -1.0 3556181 CMLD3_000197 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L12 compound treatment 6699620.0 -8480000.0 -0.57 -0.5693 -1.0 3556182 CMLD3_000198 COc1ccc2C(=O)[C@H](OC(=O)NCc3ccc4OCOc4c3)[C@H](Oc2c1)c5ccc6OCOc6c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L13 compound treatment 1.18003E8 1.03E8 6.91 6.9054 1.0 3556183 CMLD3_000199 CCCCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L14 compound treatment 2.28717E8 2.14E8 14.34 14.3404 1.0 3556185 CMLD3_000200 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(cc2)C(C)(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L15 mock treatment 1.41693E7 -1010000.0 -0.07 -0.0676 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L16 mock treatment 2.83314E7 1.32E7 0.88 0.8834 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L17 compound treatment 1.57558E7 579000.0 0.04 0.0389 1.0 3556187 CMLD3_000201 COC(=O)CC1=CO[C@@H](O)[C@H]2[C@@H]1CC=C2CO 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L18 compound treatment 1.83979E7 3220000.0 0.22 0.2163 1.0 3556189 CMLD3_000202 COC(=O)C1=NOC2(C1)C=C(Br)C(=C(Br)C2=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L19 compound treatment 6949540.0 -8230000.0 -0.55 -0.5525 -1.0 3556190 CMLD3_000203 O=C1OC(=NC21CC2)C3=CCCCC3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L20 mock treatment 1.18568E7 -3320000.0 -0.22 -0.2229 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L21 compound treatment 1.50706E7 -106000.0 -0.01 -0.0071 -1.0 3556191 CMLD3_000204 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L22 compound treatment 1.9725E7 4550000.0 0.31 0.3055 1.0 3556192 CMLD3_000205 COC(=O)[C@@H](OCc1ccccc1)/C=C/[C@H](C)Cc2cc(Br)cc(OCc3ccccc3)c2OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L23 mock treatment 7764990.0 -7410000.0 -0.5 -0.4977 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 L24 mock treatment 2.11837E7 6010000.0 0.4 0.4034 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M01 mock treatment 1.1697E7 -3480000.0 -0.23 -0.2337 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M02 compound treatment 1.85671E7 3390000.0 0.23 0.2277 1.0 3556194 CMLD3_000206 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M03 compound treatment 1.44575E7 -719000.0 -0.05 -0.0483 -1.0 3556196 CMLD3_000207 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M04 compound treatment 1.80143E7 2840000.0 0.19 0.1906 1.0 3556198 CMLD3_000208 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M05 compound treatment 1.48669E7 -310000.0 -0.02 -0.0208 -1.0 3556199 CMLD3_000209 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M06 compound treatment 7669470.0 -7510000.0 -0.5 -0.5041 -1.0 3556201 CMLD3_000210 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M07 compound treatment 1.41063E7 -1070000.0 -0.07 -0.0719 -1.0 3556203 CMLD3_000211 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M08 compound treatment 2.66312E7 1.15E7 0.77 0.7692 1.0 3556205 CMLD3_000212 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M09 mock treatment 1.79962E7 2820000.0 0.19 0.1894 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M10 mock treatment 2.01437E7 4970000.0 0.33 0.3336 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M11 compound treatment 2.11295E7 5950000.0 0.4 0.3998 1.0 3556206 CMLD3_000213 COc1ccc2O[C@@H]([C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M12 compound treatment 3017230.0 -1.22E7 -0.82 -0.8166 -1.0 2060493 CMLD3_000214 COc1ccc2c(=O)c(coc2c1)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M13 mock treatment 8068910.0 -7110000.0 -0.48 -0.4773 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M14 mock treatment 1.16762E7 -3500000.0 -0.24 -0.2351 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M15 mock treatment 1.59321E7 756000.0 0.05 0.0507 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M16 mock treatment 1.47312E7 -445000.0 -0.03 -0.0299 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M17 compound treatment 2.75237E7 1.23E7 0.83 0.8292 1.0 3556208 CMLD3_000215 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M18 compound treatment 8025620.0 -7150000.0 -0.48 -0.4802 -1.0 3556210 CMLD3_000216 COc1ccc(/C=C/NC(=O)Cc2ccc(OC)c(OC)c2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M19 compound treatment 1.53331E7 157000.0 0.01 0.0105 1.0 3556212 CMLD3_000217 CCOP(=O)(CC(C(O)c1ccccc1)C(=O)C)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M20 compound treatment 2.72238E7 1.2E7 0.81 0.809 1.0 3556213 CMLD3_000218 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)/C=C/c2ccco2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M21 compound treatment 7585390.0 -7590000.0 -0.51 -0.5098 -1.0 3556215 CMLD3_000219 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(O)(c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M22 compound treatment 1.8288E7 3110000.0 0.21 0.209 1.0 3556217 CMLD3_000220 COC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)O/C=C/C)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M23 compound treatment 1.73861E7 2210000.0 0.15 0.1484 1.0 3556219 CMLD3_000221 CC1(O)C(=O)C=C2C=C(CCCCOCc3ccccc3)OC=C2C1=O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 M24 compound treatment 1.66128E7 1440000.0 0.1 0.0965 1.0 3556220 CMLD3_000222 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N01 compound treatment 1.45858E7 -591000.0 -0.04 -0.0397 -1.0 3556222 CMLD3_000223 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N02 mock treatment 8283260.0 -6890000.0 -0.46 -0.4629 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N03 compound treatment 1.12126E7 -3960000.0 -0.27 -0.2662 -1.0 3556224 CMLD3_000224 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N04 compound treatment 6000700.0 -9180000.0 -0.62 -0.6162 -1.0 3556226 CMLD3_000225 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3[C@H](O)[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N05 compound treatment 3.17073E7 1.65E7 1.11 1.1101 1.0 3556228 CMLD3_000226 COc1ccc2O[C@@H]([C@@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N06 compound treatment 4896270.0 -1.03E7 -0.69 -0.6904 -1.0 3556229 CMLD3_000227 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4cccc(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N07 compound treatment 2.25692E7 7390000.0 0.5 0.4965 1.0 3556231 CMLD3_000228 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N08 compound treatment 1.52909E7 114000.0 0.01 0.0077 1.0 3556233 CMLD3_000229 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N09 mock treatment 1.11736E7 -4000000.0 -0.27 -0.2688 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N10 mock treatment 2.92283E7 1.41E7 0.94 0.9437 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N11 mock treatment 1.76788E7 2500000.0 0.17 0.168 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N12 compound treatment 2.42901E7 9110000.0 0.61 0.612 1.0 3556235 CMLD3_000230 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NCc4ccco4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N13 mock treatment 2.21542E7 6980000.0 0.47 0.4686 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N14 mock treatment 1.02325E7 -4940000.0 -0.33 -0.332 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N15 compound treatment 2.32528E7 8080000.0 0.54 0.5424 1.0 3556237 CMLD3_000231 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccc(Cl)cc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N16 compound treatment 1.70887E7 1910000.0 0.13 0.1284 1.0 3556239 CMLD3_000232 CCCCC#C[C@H]1O[C@H](CO)[C@@H](Oc2ccc(OC)cc2)C=C1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N17 compound treatment 2.36181E7 8440000.0 0.57 0.5669 1.0 3556241 CMLD3_000233 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccc(c1)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N18 compound treatment 3.19344E7 1.68E7 1.13 1.1254 1.0 3556243 CMLD3_000234 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccs1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N19 compound treatment 1.0746E7 -4430000.0 -0.3 -0.2975 -1.0 3556191 CMLD3_000235 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N20 compound treatment 2.7805E7 1.26E7 0.85 0.8481 1.0 3556245 CMLD3_000236 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N21 mock treatment 7692560.0 -7480000.0 -0.5 -0.5026 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N22 compound treatment 2.201E7 6830000.0 0.46 0.4589 1.0 3556247 CMLD3_000237 CCC1(CC2(CC)C(CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N23 compound treatment 1.24452E7 -2730000.0 -0.18 -0.1834 -1.0 3556249 CMLD3_000238 CC1(CC2(C)C(CC1=O)c3ccc(F)cc3)C=C2/C=C/c4ccc(F)cc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 N24 mock treatment 1.16947E7 -3480000.0 -0.23 -0.2338 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O01 compound treatment 2.44088E7 9230000.0 0.62 0.62 1.0 3556251 CMLD3_000239 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H](C)C3CCCCC3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O02 compound treatment 1.29414E7 -2240000.0 -0.15 -0.1501 -1.0 3556253 CMLD3_000240 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O03 compound treatment 2.01983E7 5020000.0 0.34 0.3372 1.0 3556254 CMLD3_000241 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O04 compound treatment 1.07583E7 -4420000.0 -0.3 -0.2967 -1.0 3556256 CMLD3_000242 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O05 compound treatment 1.05779E7 -4600000.0 -0.31 -0.3088 -1.0 3131449 CMLD3_000243 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O06 compound treatment 4.12315E7 2.61E7 1.75 1.7497 1.0 3556257 CMLD3_000244 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O07 mock treatment 1.48318E7 -345000.0 -0.02 -0.0231 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O08 mock treatment 2812110.0 -1.24E7 -0.83 -0.8303 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O09 mock treatment 1.38065E7 -1370000.0 -0.09 -0.092 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O10 compound treatment 3.02988E7 1.51E7 1.02 1.0155 1.0 3556259 CMLD3_000245 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O11 mock treatment 5015170.0 -1.02E7 -0.68 -0.6824 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O12 mock treatment 1.74167E7 2240000.0 0.15 0.1504 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O13 compound treatment 2.21396E8 2.06E8 13.85 13.8488 1.0 3556261 CMLD3_000246 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O14 compound treatment 3.64988E8 3.5E8 23.49 23.4918 1.0 3556263 CMLD3_000247 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(C)cc2C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O15 compound treatment 9263490.0 -5910000.0 -0.4 -0.3971 -1.0 3556265 CMLD3_000248 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccc(Cl)cc3)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O16 compound treatment 7.26308E7 5.75E7 3.86 3.8584 1.0 3556008 CMLD3_000249 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O17 compound treatment 1.50177E7 -159000.0 -0.01 -0.0107 -1.0 3556266 CMLD3_000250 CC(=CCC1(CC=C(C)C)C(=O)C(=C2OC(C)(C)CCC2(CC=C(C)C)C1=O)C(=O)c3ccccc3)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O18 compound treatment 3.79655E7 2.28E7 1.53 1.5304 1.0 3556267 CMLD3_000251 CC1(CC2(C)C(CC1=O)/C=C/c3ccccc3)C=C2/C=C/C=C/c4ccccc4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O19 compound treatment 3.02313E7 1.51E7 1.01 1.011 1.0 1125649 CMLD3_000252 CNc1ccccc1C(=O)OCC(=O)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O20 mock treatment 1.83044E7 3130000.0 0.21 0.2101 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O21 mock treatment 8811790.0 -6360000.0 -0.43 -0.4274 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O22 compound treatment 1.01192E7 -5060000.0 -0.34 -0.3396 -1.0 3556269 CMLD3_000253 CNc1ccccc1C(=O)OCC(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O23 compound treatment 1.11467E7 -4030000.0 -0.27 -0.2706 -1.0 3556270 CMLD3_000254 COc1ccc(/C=C/NC(=O)c2ccc(OC)cc2)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 O24 compound treatment 2163550.0 -1.3E7 -0.87 -0.8739 -1.0 3556272 CMLD3_000255 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccc(Cl)cc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P01 compound treatment 1.76948E7 2520000.0 0.17 0.1691 1.0 3556274 CMLD3_000256 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F)C(C)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P02 mock treatment 1.71512E7 1970000.0 0.13 0.1326 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P03 mock treatment 1.58541E7 678000.0 0.05 0.0455 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P04 compound treatment 4310910.0 -1.09E7 -0.73 -0.7297 -1.0 3556276 CMLD3_000257 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P05 compound treatment 2.35836E8 2.21E8 14.82 14.8185 1.0 3011477 CMLD3_000258 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P06 compound treatment 3.66956E7 2.15E7 1.45 1.4451 1.0 3556277 CMLD3_000259 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P07 compound treatment 1.27379E7 -2440000.0 -0.16 -0.1638 -1.0 3556279 CMLD3_000260 COc1ccc2O[C@H]([C@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P08 compound treatment 2862210.0 -1.23E7 -0.83 -0.827 -1.0 3556280 CMLD3_000261 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P09 mock treatment 1.9575E7 4400000.0 0.3 0.2954 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P10 compound treatment 1.33263E7 -1850000.0 -0.12 -0.1242 -1.0 3556282 CMLD3_000262 COc1ccc2C(=O)[C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P11 mock treatment 1.77069E7 2530000.0 0.17 0.1699 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P12 mock treatment 2.07116E7 5540000.0 0.37 0.3717 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P13 compound treatment 1.02581E7 -4920000.0 -0.33 -0.3303 -1.0 3556284 CMLD3_000263 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2ccccc2 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P14 compound treatment 3.35293E8 3.2E8 21.5 21.4976 1.0 3556286 CMLD3_000264 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(F)cc2F 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P15 compound treatment 2.62836E7 1.11E7 0.75 0.7459 1.0 3556288 CMLD3_000265 Cc1cc(C)cc(/C=C/[C@@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P16 compound treatment 1.67674E7 1590000.0 0.11 0.1068 1.0 3556289 CMLD3_000266 Cc1cc(F)ccc1O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc4OCOc4c3 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P17 compound treatment 2.50823E7 9910000.0 0.67 0.6652 1.0 3556073 CMLD3_000267 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P18 compound treatment 1.11896E7 -3990000.0 -0.27 -0.2677 -1.0 3556291 CMLD3_000268 COc1ccc(cc1)C(=O)Oc2cc(OC)cc(OC)c2C(=O)C 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P19 compound treatment 1.50679E7 -109000.0 -0.01 -0.0073 -1.0 3556292 CMLD3_000269 CC(=C)C(O)/C=C/c1ccc(Br)cc1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P20 mock treatment 1.12146E7 -3960000.0 -0.27 -0.2661 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P21 compound treatment 2.56203E7 1.04E7 0.7 0.7014 1.0 3556294 CMLD3_000270 COC(=O)N[C@@H](/C=C/c1ccco1)[C@@]2(CCCC2=O)C(=O)OC 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P22 compound treatment 6963780.0 -8210000.0 -0.55 -0.5515 -1.0 3556296 CMLD3_000271 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(F)c(F)c(F)c2)c3cc(F)c(F)c(F)c3)C(O)(c4cc(F)c(F)c(F)c4)c5cc(F)c(F)c(F)c5 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P23 compound treatment 1.1994E7 -3180000.0 -0.21 -0.2137 -1.0 3556298 CMLD3_000272 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccco1 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.2284 P24 mock treatment 5476770.0 -9700000.0 -0.65 -0.6514 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A01 mock treatment 1.83902E7 3570000.0 0.24 0.2398 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A02 mock treatment 7950620.0 -6870000.0 -0.46 -0.4612 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A03 mock treatment 1.01296E7 -4690000.0 -0.31 -0.3149 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A04 mock treatment 1.91798E7 4360000.0 0.29 0.2929 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A05 mock treatment 1.60585E7 1240000.0 0.08 0.0832 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A06 mock treatment 1.42634E7 -555000.0 -0.04 -0.0373 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A07 mock treatment 1.87906E7 3970000.0 0.27 0.2667 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A08 mock treatment 6266940.0 -8550000.0 -0.57 -0.5743 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A09 mock treatment 1.04066E7 -4410000.0 -0.3 -0.2963 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A10 mock treatment 1.9876E7 5060000.0 0.34 0.3396 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A11 mock treatment 4475180.0 -1.03E7 -0.69 -0.6946 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A12 mock treatment 1.25911E7 -2230000.0 -0.15 -0.1496 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A13 mock treatment 3.18459E7 1.7E7 1.14 1.1435 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A14 mock treatment 1.42428E7 -576000.0 -0.04 -0.0387 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A15 mock treatment 1.16205E7 -3200000.0 -0.21 -0.2148 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A16 mock treatment 6860290.0 -7960000.0 -0.53 -0.5345 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A17 mock treatment 6191220.0 -8630000.0 -0.58 -0.5794 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A18 mock treatment 1.65933E7 1770000.0 0.12 0.1192 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A19 mock treatment 1.49711E7 152000.0 0.01 0.0102 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A20 mock treatment 1.54273E7 608000.0 0.04 0.0409 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A21 mock treatment 1.46401E7 -179000.0 -0.01 -0.012 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A22 mock treatment 1.24312E7 -2390000.0 -0.16 -0.1603 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A23 mock treatment 6747730.0 -8070000.0 -0.54 -0.542 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base A24 mock treatment 1.0126E7 -4690000.0 -0.32 -0.3152 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B01 mock treatment 1.31566E7 -1660000.0 -0.11 -0.1116 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B02 mock treatment 1.32216E7 -1600000.0 -0.11 -0.1073 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B03 mock treatment 6875380.0 -7940000.0 -0.53 -0.5334 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B04 mock treatment 1.46867E7 -132000.0 -0.01 -0.0089 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B05 mock treatment 1.20473E7 -2770000.0 -0.19 -0.1861 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B06 mock treatment 1.85805E7 3760000.0 0.25 0.2526 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B07 mock treatment 1.01654E7 -4650000.0 -0.31 -0.3125 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B08 mock treatment 2.13179E7 6500000.0 0.44 0.4364 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B09 mock treatment 8590900.0 -6230000.0 -0.42 -0.4182 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B10 mock treatment 1.18798E7 -2940000.0 -0.2 -0.1974 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B11 mock treatment 1.09153E7 -3900000.0 -0.26 -0.2621 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B12 mock treatment 1.83382E7 3520000.0 0.24 0.2363 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B13 mock treatment 2.44727E7 9650000.0 0.65 0.6483 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B14 mock treatment 2.16242E7 6810000.0 0.46 0.457 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B15 mock treatment 3414190.0 -1.14E7 -0.77 -0.7659 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B16 mock treatment 8991500.0 -5830000.0 -0.39 -0.3913 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B17 mock treatment 1.92744E7 4460000.0 0.3 0.2992 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B18 mock treatment 1.43755E7 -443000.0 -0.03 -0.0298 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B19 mock treatment 8324690.0 -6490000.0 -0.44 -0.4361 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B20 mock treatment 1.56733E7 854000.0 0.06 0.0574 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B21 mock treatment 1.54752E7 656000.0 0.04 0.0441 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B22 mock treatment 6559440.0 -8260000.0 -0.55 -0.5547 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B23 mock treatment 1.05651E7 -4250000.0 -0.29 -0.2857 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base B24 mock treatment 0.0 -1.48E7 -1.0 -0.9952 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C01 mock treatment 2.49011E7 1.01E7 0.68 0.6771 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C02 mock treatment 2.13672E7 6550000.0 0.44 0.4398 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C03 mock treatment 1.76028E7 2780000.0 0.19 0.187 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C04 mock treatment 1.09772E7 -3840000.0 -0.26 -0.258 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C05 mock treatment 1.58971E7 1080000.0 0.07 0.0724 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C06 mock treatment 1.28546E7 -1960000.0 -0.13 -0.1319 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C07 mock treatment 2.18114E7 6990000.0 0.47 0.4696 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C08 mock treatment 1.48346E7 15800.0 0.0 0.0011 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C09 mock treatment 1.79041E7 3090000.0 0.21 0.2072 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C10 mock treatment 3.23856E7 1.76E7 1.18 1.1797 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C11 mock treatment 1.18457E7 -2970000.0 -0.2 -0.1997 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C12 mock treatment 1.62976E7 1480000.0 0.1 0.0993 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C13 mock treatment 1.63688E7 1550000.0 0.1 0.1041 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C14 mock treatment 1551090.0 -1.33E7 -0.89 -0.891 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C15 mock treatment 1.06718E7 -4150000.0 -0.28 -0.2785 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C16 mock treatment 1.06884E7 -4130000.0 -0.28 -0.2774 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C17 mock treatment 9711410.0 -5110000.0 -0.34 -0.343 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C18 mock treatment 9775360.0 -5040000.0 -0.34 -0.3387 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C19 mock treatment 2.99828E7 1.52E7 1.02 1.0183 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C20 mock treatment 2.20027E7 7180000.0 0.48 0.4824 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C21 mock treatment 7364300.0 -7450000.0 -0.5 -0.5006 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C22 mock treatment 1.08715E7 -3950000.0 -0.27 -0.2651 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C23 mock treatment 1.15576E7 -3260000.0 -0.22 -0.219 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base C24 mock treatment 2634670.0 -1.22E7 -0.82 -0.8182 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D01 mock treatment 1.24143E7 -2400000.0 -0.16 -0.1615 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D02 mock treatment 9392620.0 -5430000.0 -0.36 -0.3644 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D03 mock treatment 1927360.0 -1.29E7 -0.87 -0.8657 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D04 mock treatment 1.5855E7 1040000.0 0.07 0.0696 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D05 mock treatment 2.86525E7 1.38E7 0.93 0.929 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D06 mock treatment 2.78855E7 1.31E7 0.88 0.8775 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D07 mock treatment 1.73093E7 2490000.0 0.17 0.1672 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D08 mock treatment 2.14447E7 6630000.0 0.44 0.445 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D09 mock treatment 1.18576E7 -2960000.0 -0.2 -0.1989 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D10 mock treatment 1.75921E7 2770000.0 0.19 0.1862 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D11 mock treatment 3982300.0 -1.08E7 -0.73 -0.7277 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D12 mock treatment 3.18633E7 1.7E7 1.14 1.1446 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D13 mock treatment 2045860.0 -1.28E7 -0.86 -0.8578 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D14 mock treatment 9620540.0 -5200000.0 -0.35 -0.3491 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D15 mock treatment 3117920.0 -1.17E7 -0.79 -0.7858 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D16 mock treatment 1.62213E7 1400000.0 0.09 0.0942 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D17 mock treatment 3.46249E7 1.98E7 1.33 1.3301 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D18 mock treatment 9704190.0 -5110000.0 -0.34 -0.3435 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D19 mock treatment 1504770.0 -1.33E7 -0.89 -0.8941 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D20 mock treatment 7748900.0 -7070000.0 -0.47 -0.4748 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D21 mock treatment 4434930.0 -1.04E7 -0.7 -0.6973 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D22 mock treatment 7719860.0 -7100000.0 -0.48 -0.4767 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D23 mock treatment 7943470.0 -6880000.0 -0.46 -0.4617 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base D24 mock treatment 1.80841E7 3270000.0 0.22 0.2193 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E01 mock treatment 1.0112E7 -4710000.0 -0.32 -0.3161 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E02 mock treatment 1.05116E7 -4310000.0 -0.29 -0.2893 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E03 mock treatment 6471620.0 -8350000.0 -0.56 -0.5606 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E04 mock treatment 1.03193E7 -4500000.0 -0.3 -0.3022 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E05 mock treatment 1.79256E7 3110000.0 0.21 0.2086 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E06 mock treatment 2.23356E7 7520000.0 0.5 0.5048 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E07 mock treatment 2.37406E7 8920000.0 0.6 0.5991 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E08 mock treatment 6682110.0 -8140000.0 -0.55 -0.5464 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E09 mock treatment 8896160.0 -5920000.0 -0.4 -0.3977 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E10 mock treatment 1.43322E7 -487000.0 -0.03 -0.0327 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E11 mock treatment 4.93889E7 3.46E7 2.32 2.3216 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E12 mock treatment 2.32889E7 8470000.0 0.57 0.5688 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E13 mock treatment 1.13066E7 -3510000.0 -0.24 -0.2359 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E14 mock treatment 1.07015E7 -4120000.0 -0.28 -0.2765 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E15 mock treatment 1.08377E7 -3980000.0 -0.27 -0.2674 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E16 mock treatment 4724420.0 -1.01E7 -0.68 -0.6779 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E17 mock treatment 5918670.0 -8900000.0 -0.6 -0.5977 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E18 mock treatment 4274140.0 -1.05E7 -0.71 -0.7081 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E19 mock treatment 9252240.0 -5570000.0 -0.37 -0.3738 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E20 mock treatment 1.62096E7 1390000.0 0.09 0.0934 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E21 mock treatment 7474020.0 -7340000.0 -0.49 -0.4932 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E22 mock treatment 9191810.0 -5630000.0 -0.38 -0.3779 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E23 mock treatment 6722990.0 -8100000.0 -0.54 -0.5437 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base E24 mock treatment 4814080.0 -1.0E7 -0.67 -0.6719 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F01 mock treatment 2.32475E7 8430000.0 0.57 0.566 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F02 mock treatment 1.42918E7 -527000.0 -0.04 -0.0354 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F03 mock treatment 1.51298E7 311000.0 0.02 0.0209 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F04 mock treatment 1.26747E7 -2140000.0 -0.14 -0.144 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F05 mock treatment 1.41855E7 -633000.0 -0.04 -0.0425 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F06 mock treatment 1.03304E7 -4490000.0 -0.3 -0.3014 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F07 mock treatment 2.23417E7 7520000.0 0.51 0.5052 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F08 mock treatment 1.40152E7 -804000.0 -0.05 -0.054 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F09 mock treatment 1.84122E7 3590000.0 0.24 0.2413 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F10 mock treatment 5365040.0 -9450000.0 -0.63 -0.6349 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F11 mock treatment 1.78163E7 3000000.0 0.2 0.2013 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F12 mock treatment 1.11221E7 -3700000.0 -0.25 -0.2483 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F13 mock treatment 6294610.0 -8520000.0 -0.57 -0.5724 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F14 mock treatment 9245780.0 -5570000.0 -0.37 -0.3743 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F15 mock treatment 5363500.0 -9460000.0 -0.63 -0.635 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F16 mock treatment 5841420.0 -8980000.0 -0.6 -0.6029 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F17 mock treatment 5313150.0 -9510000.0 -0.64 -0.6384 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F18 mock treatment 9113870.0 -5700000.0 -0.38 -0.3831 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F19 mock treatment 2160180.0 -1.27E7 -0.85 -0.8501 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F20 mock treatment 1.53999E7 581000.0 0.04 0.039 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F21 mock treatment 4722830.0 -1.01E7 -0.68 -0.678 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F22 mock treatment 1.42606E7 -558000.0 -0.04 -0.0375 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F23 mock treatment 1.02001E7 -4620000.0 -0.31 -0.3102 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base F24 mock treatment 1.74071E7 2590000.0 0.17 0.1738 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G01 mock treatment 1.7542E7 2720000.0 0.18 0.1829 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G02 mock treatment 2.00367E7 5220000.0 0.35 0.3504 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G03 mock treatment 5991360.0 -8830000.0 -0.59 -0.5928 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G04 mock treatment 2.22817E7 7460000.0 0.5 0.5012 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G05 mock treatment 1.88096E7 3990000.0 0.27 0.268 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G06 mock treatment 1.04414E7 -4380000.0 -0.29 -0.294 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G07 mock treatment 1.34527E7 -1370000.0 -0.09 -0.0917 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G08 mock treatment 7050020.0 -7770000.0 -0.52 -0.5217 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G09 mock treatment 1.14712E7 -3350000.0 -0.22 -0.2248 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G10 mock treatment 5875820.0 -8940000.0 -0.6 -0.6006 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G11 mock treatment 1.57374E7 919000.0 0.06 0.0617 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G12 mock treatment 8373680.0 -6450000.0 -0.43 -0.4328 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G13 mock treatment 1.50639E7 245000.0 0.02 0.0165 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G14 mock treatment 4351040.0 -1.05E7 -0.7 -0.703 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G15 mock treatment 5556770.0 -9260000.0 -0.62 -0.622 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G16 mock treatment 4907420.0 -9910000.0 -0.67 -0.6656 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G17 mock treatment 1.85024E7 3680000.0 0.25 0.2474 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G18 mock treatment 2.22879E7 7470000.0 0.5 0.5016 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G19 mock treatment 7679380.0 -7140000.0 -0.48 -0.4795 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G20 mock treatment 2074140.0 -1.27E7 -0.86 -0.8559 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G21 mock treatment 6576500.0 -8240000.0 -0.55 -0.5535 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G22 mock treatment 3208660.0 -1.16E7 -0.78 -0.7797 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G23 mock treatment 6989970.0 -7830000.0 -0.53 -0.5258 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base G24 mock treatment 1.40782E7 -741000.0 -0.05 -0.0497 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H01 mock treatment 1.63323E7 1510000.0 0.1 0.1016 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H02 mock treatment 2.07196E7 5900000.0 0.4 0.3963 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H03 mock treatment 1.44645E7 -354000.0 -0.02 -0.0238 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H04 mock treatment 2.93424E7 1.45E7 0.98 0.9753 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H05 mock treatment 2.05092E7 5690000.0 0.38 0.3821 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H06 mock treatment 1.42987E7 -520000.0 -0.03 -0.0349 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H07 mock treatment 3.31834E7 1.84E7 1.23 1.2333 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H08 mock treatment 1.23617E7 -2460000.0 -0.17 -0.165 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H09 mock treatment 1.48696E7 50800.0 0.0 0.0034 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H10 mock treatment 9808300.0 -5010000.0 -0.34 -0.3365 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H11 mock treatment 1.50776E7 259000.0 0.02 0.0174 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H12 mock treatment 1.2061E7 -2760000.0 -0.19 -0.1852 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H13 mock treatment 0.0 -1.48E7 -1.0 -0.9952 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H14 mock treatment 0.0 -1.48E7 -1.0 -0.9952 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H15 mock treatment 1.67732E7 1950000.0 0.13 0.1312 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H16 mock treatment 5087260.0 -9730000.0 -0.65 -0.6535 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H17 mock treatment 2.18204E7 7000000.0 0.47 0.4702 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H18 mock treatment 1.72226E7 2400000.0 0.16 0.1614 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H19 mock treatment 1.18113E7 -3010000.0 -0.2 -0.202 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H20 mock treatment 2.25554E7 7740000.0 0.52 0.5196 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H21 mock treatment 1.65458E7 1730000.0 0.12 0.116 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H22 mock treatment 8359650.0 -6460000.0 -0.43 -0.4338 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H23 mock treatment 3127780.0 -1.17E7 -0.79 -0.7851 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base H24 mock treatment 1.19937E7 -2830000.0 -0.19 -0.1897 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I01 mock treatment 6600420.0 -8220000.0 -0.55 -0.5519 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I02 mock treatment 1.65188E7 1700000.0 0.11 0.1142 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I03 mock treatment 2.65629E7 1.17E7 0.79 0.7887 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I04 mock treatment 1.60294E7 1210000.0 0.08 0.0813 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I05 mock treatment 1.38675E7 -951000.0 -0.06 -0.0639 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I06 mock treatment 1.8385E7 3570000.0 0.24 0.2395 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I07 mock treatment 2.90778E7 1.43E7 0.96 0.9576 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I08 mock treatment 1.36997E7 -1120000.0 -0.08 -0.0752 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I09 mock treatment 2.20417E7 7220000.0 0.49 0.4851 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I10 mock treatment 1.8402E7 3580000.0 0.24 0.2406 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I11 mock treatment 6922820.0 -7900000.0 -0.53 -0.5303 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I12 mock treatment 5739360.0 -9080000.0 -0.61 -0.6097 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I13 mock treatment 2.83436E7 1.35E7 0.91 0.9083 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I14 mock treatment 1.44172E7 -402000.0 -0.03 -0.027 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I15 mock treatment 1.80763E7 3260000.0 0.22 0.2188 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I16 mock treatment 2.01844E7 5370000.0 0.36 0.3603 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I17 mock treatment 3.36226E7 1.88E7 1.26 1.2628 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I18 mock treatment 3.43468E7 1.95E7 1.31 1.3114 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I19 mock treatment 2.22242E7 7410000.0 0.5 0.4973 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I20 mock treatment 7322460.0 -7500000.0 -0.5 -0.5034 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I21 mock treatment 3.8463E7 2.36E7 1.59 1.5878 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I22 mock treatment 1.06014E7 -4220000.0 -0.28 -0.2832 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I23 mock treatment 2.21422E7 7320000.0 0.49 0.4918 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base I24 mock treatment 2.38064E7 8990000.0 0.6 0.6036 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J01 mock treatment 4.00635E7 2.52E7 1.7 1.6953 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J02 mock treatment 2.60745E7 1.13E7 0.76 0.7559 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J03 mock treatment 2.1478E7 6660000.0 0.45 0.4472 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J04 mock treatment 1.07463E7 -4070000.0 -0.27 -0.2735 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J05 mock treatment 1.0343E7 -4480000.0 -0.3 -0.3006 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J06 mock treatment 8928210.0 -5890000.0 -0.4 -0.3956 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J07 mock treatment 1.47774E7 -41400.0 0.0 -0.0028 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J08 mock treatment 1.58078E7 989000.0 0.07 0.0664 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J09 mock treatment 1.89891E7 4170000.0 0.28 0.2801 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J10 mock treatment 1.03592E7 -4460000.0 -0.3 -0.2995 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J11 mock treatment 1.48299E7 11100.0 0.0 7.0E-4 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J12 mock treatment 4708020.0 -1.01E7 -0.68 -0.679 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J13 mock treatment 4523570.0 -1.03E7 -0.69 -0.6914 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J14 mock treatment 3.15802E7 1.68E7 1.13 1.1256 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J15 mock treatment 1.23393E7 -2480000.0 -0.17 -0.1665 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J16 mock treatment 1.53898E7 571000.0 0.04 0.0383 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J17 mock treatment 1.73394E7 2520000.0 0.17 0.1693 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J18 mock treatment 2.51204E7 1.03E7 0.69 0.6918 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J19 mock treatment 1.46426E7 -176000.0 -0.01 -0.0118 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J20 mock treatment 1.44156E7 -403000.0 -0.03 -0.0271 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J21 mock treatment 1.55326E7 714000.0 0.05 0.0479 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J22 mock treatment 1.28327E7 -1990000.0 -0.13 -0.1334 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J23 mock treatment 1.2727E7 -2090000.0 -0.14 -0.1405 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base J24 mock treatment 2.29186E7 8100000.0 0.54 0.5439 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K01 mock treatment 1.75338E7 2710000.0 0.18 0.1823 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K02 mock treatment 2.22882E7 7470000.0 0.5 0.5016 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K03 mock treatment 1.09376E7 -3880000.0 -0.26 -0.2606 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K04 mock treatment 1.43372E7 -482000.0 -0.03 -0.0323 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K05 mock treatment 8964130.0 -5850000.0 -0.39 -0.3932 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K06 mock treatment 1.73084E7 2490000.0 0.17 0.1672 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K07 mock treatment 1.34204E7 -1400000.0 -0.09 -0.0939 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K08 mock treatment 1.69726E7 2150000.0 0.14 0.1446 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K09 mock treatment 1.70185E7 2200000.0 0.15 0.1477 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K10 mock treatment 1.05827E7 -4240000.0 -0.28 -0.2845 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K11 mock treatment 1.13036E7 -3520000.0 -0.24 -0.2361 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K12 mock treatment 2.41837E7 9360000.0 0.63 0.6289 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K13 mock treatment 2.97941E7 1.5E7 1.01 1.0057 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K14 mock treatment 2.02041E7 5390000.0 0.36 0.3616 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K15 mock treatment 1.84305E7 3610000.0 0.24 0.2425 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K16 mock treatment 3795310.0 -1.1E7 -0.74 -0.7403 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K17 mock treatment 2.01063E7 5290000.0 0.36 0.3551 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K18 mock treatment 1.10059E7 -3810000.0 -0.26 -0.2561 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K19 mock treatment 1.96091E7 4790000.0 0.32 0.3217 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K20 mock treatment 2.06732E7 5850000.0 0.39 0.3932 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K21 mock treatment 2.13774E7 6560000.0 0.44 0.4404 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K22 mock treatment 2.18254E7 7010000.0 0.47 0.4705 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K23 mock treatment 1.17375E7 -3080000.0 -0.21 -0.2069 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base K24 mock treatment 6476460.0 -8340000.0 -0.56 -0.5602 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L01 mock treatment 2.17104E7 6890000.0 0.46 0.4628 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L02 mock treatment 1.52558E7 437000.0 0.03 0.0293 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L03 mock treatment 1.99316E7 5110000.0 0.34 0.3433 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L04 mock treatment 1.61663E7 1350000.0 0.09 0.0905 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L05 mock treatment 3188580.0 -1.16E7 -0.78 -0.781 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L06 mock treatment 1.70855E7 2270000.0 0.15 0.1522 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L07 mock treatment 2.23856E7 7570000.0 0.51 0.5081 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L08 mock treatment 2.13336E7 6510000.0 0.44 0.4375 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L09 mock treatment 2.98823E7 1.51E7 1.01 1.0116 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L10 mock treatment 1.45787E7 -240000.0 -0.02 -0.0161 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L11 mock treatment 1.49028E7 84000.0 0.01 0.0056 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L12 mock treatment 1.29899E7 -1830000.0 -0.12 -0.1228 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L13 mock treatment 8912300.0 -5910000.0 -0.4 -0.3967 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L14 mock treatment 1.54823E7 663000.0 0.04 0.0446 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L15 mock treatment 1.35724E7 -1250000.0 -0.08 -0.0837 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L16 mock treatment 1.25016E7 -2320000.0 -0.16 -0.1556 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L17 mock treatment 6203570.0 -8620000.0 -0.58 -0.5786 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L18 mock treatment 1.27011E7 -2120000.0 -0.14 -0.1422 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L19 mock treatment 1.2303E7 -2520000.0 -0.17 -0.169 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L20 mock treatment 1.80115E7 3190000.0 0.21 0.2144 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L21 mock treatment 1.12647E7 -3550000.0 -0.24 -0.2387 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L22 mock treatment 4573070.0 -1.02E7 -0.69 -0.6881 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L23 mock treatment 2.432E7 9500000.0 0.64 0.6381 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base L24 mock treatment 1.28502E7 -1970000.0 -0.13 -0.1322 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M01 mock treatment 3.54481E7 2.06E7 1.39 1.3854 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M02 mock treatment 1.26572E7 -2160000.0 -0.15 -0.1452 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M03 mock treatment 2.01692E7 5350000.0 0.36 0.3593 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M04 mock treatment 9197500.0 -5620000.0 -0.38 -0.3775 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M05 mock treatment 2.31565E7 8340000.0 0.56 0.5599 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M06 mock treatment 1.89078E7 4090000.0 0.27 0.2746 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M07 mock treatment 1.73673E7 2550000.0 0.17 0.1711 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M08 mock treatment 1.9669E7 4850000.0 0.33 0.3257 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M09 mock treatment 1.58329E7 1010000.0 0.07 0.0681 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M10 mock treatment 1.69982E7 2180000.0 0.15 0.1464 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M11 mock treatment 2.03784E7 5560000.0 0.37 0.3734 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M12 mock treatment 2.41544E7 9340000.0 0.63 0.6269 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M13 mock treatment 7453780.0 -7370000.0 -0.49 -0.4946 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M14 mock treatment 8488140.0 -6330000.0 -0.43 -0.4251 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M15 mock treatment 1.67932E7 1970000.0 0.13 0.1326 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M16 mock treatment 2.03318E7 5510000.0 0.37 0.3702 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M17 mock treatment 2.33868E7 8570000.0 0.58 0.5754 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M18 mock treatment 1.05972E7 -4220000.0 -0.28 -0.2835 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M19 mock treatment 2.12232E7 6400000.0 0.43 0.4301 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M20 mock treatment 1.82666E7 3450000.0 0.23 0.2315 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M21 mock treatment 1.15536E7 -3270000.0 -0.22 -0.2193 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M22 mock treatment 1.5083E7 264000.0 0.02 0.0177 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M23 mock treatment 1.78086E7 2990000.0 0.2 0.2008 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base M24 mock treatment 2.41281E7 9310000.0 0.63 0.6252 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N01 mock treatment 9132370.0 -5690000.0 -0.38 -0.3819 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N02 mock treatment 2.39069E7 9090000.0 0.61 0.6103 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N03 mock treatment 2.2339E7 7520000.0 0.51 0.505 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N04 mock treatment 3.42559E7 1.94E7 1.31 1.3053 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N05 mock treatment 8100560.0 -6720000.0 -0.45 -0.4512 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N06 mock treatment 1.08089E7 -4010000.0 -0.27 -0.2693 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N07 mock treatment 1.53365E7 518000.0 0.03 0.0348 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N08 mock treatment 1.86037E7 3780000.0 0.25 0.2542 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N09 mock treatment 1.66285E7 1810000.0 0.12 0.1215 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N10 mock treatment 1.18539E7 -2960000.0 -0.2 -0.1991 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N11 mock treatment 1.24286E7 -2390000.0 -0.16 -0.1605 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N12 mock treatment 2.29692E7 8150000.0 0.55 0.5473 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N13 mock treatment 2.61708E7 1.14E7 0.76 0.7623 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N14 mock treatment 3.14745E7 1.67E7 1.12 1.1185 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N15 mock treatment 7008300.0 -7810000.0 -0.52 -0.5245 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N16 mock treatment 3.25136E7 1.77E7 1.19 1.1883 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N17 mock treatment 1.03901E7 -4430000.0 -0.3 -0.2974 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N18 mock treatment 2.7491E7 1.27E7 0.85 0.851 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N19 mock treatment 1.56293E7 810000.0 0.05 0.0544 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N20 mock treatment 2.03485E7 5530000.0 0.37 0.3713 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N21 mock treatment 2.71065E7 1.23E7 0.83 0.8252 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N22 mock treatment 1.91886E7 4370000.0 0.29 0.2935 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N23 mock treatment 2.20551E7 7240000.0 0.49 0.486 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base N24 mock treatment 7384270.0 -7430000.0 -0.5 -0.4993 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O01 mock treatment 2.70786E7 1.23E7 0.82 0.8233 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O02 mock treatment 8438690.0 -6380000.0 -0.43 -0.4285 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O03 mock treatment 9871730.0 -4950000.0 -0.33 -0.3322 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O04 mock treatment 2.05411E7 5720000.0 0.38 0.3843 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O05 mock treatment 2.04159E7 5600000.0 0.38 0.3759 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O06 mock treatment 6371950.0 -8450000.0 -0.57 -0.5673 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O07 mock treatment 3.88287E7 2.4E7 1.61 1.6124 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O08 mock treatment 3.74007E7 2.26E7 1.52 1.5165 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O09 mock treatment 1.64102E7 1590000.0 0.11 0.1069 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O10 mock treatment 1.83104E7 3490000.0 0.23 0.2345 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O11 mock treatment 1.72652E7 2450000.0 0.16 0.1643 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O12 mock treatment 1.98684E7 5050000.0 0.34 0.3391 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O13 mock treatment 9518100.0 -5300000.0 -0.36 -0.356 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O14 mock treatment 7338910.0 -7480000.0 -0.5 -0.5023 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O15 mock treatment 1.29958E7 -1820000.0 -0.12 -0.1224 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O16 mock treatment 1.06851E7 -4130000.0 -0.28 -0.2776 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O17 mock treatment 5494980.0 -9320000.0 -0.63 -0.6261 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O18 mock treatment 6620690.0 -8200000.0 -0.55 -0.5506 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O19 mock treatment 4.32413E7 2.84E7 1.91 1.9087 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O20 mock treatment 6144590.0 -8670000.0 -0.58 -0.5825 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O21 mock treatment 3.03898E7 1.56E7 1.05 1.0457 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O22 mock treatment 1.92595E7 4440000.0 0.3 0.2982 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O23 mock treatment 2.77932E7 1.3E7 0.87 0.8713 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base O24 mock treatment 1.26594E7 -2160000.0 -0.15 -0.145 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P01 mock treatment 2.50491E7 1.02E7 0.69 0.687 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P02 mock treatment 2.27088E7 7890000.0 0.53 0.5299 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P03 mock treatment 8433570.0 -6390000.0 -0.43 -0.4288 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P04 mock treatment 1.9466E7 4650000.0 0.31 0.3121 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P05 mock treatment 1.37437E7 -1080000.0 -0.07 -0.0722 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P06 mock treatment 3.0462E7 1.56E7 1.05 1.0505 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P07 mock treatment 8981860.0 -5840000.0 -0.39 -0.392 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P08 mock treatment 9349060.0 -5470000.0 -0.37 -0.3673 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P09 mock treatment 1.05734E7 -4250000.0 -0.29 -0.2851 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P10 mock treatment 1.53704E7 552000.0 0.04 0.037 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P11 mock treatment 2.65665E7 1.17E7 0.79 0.7889 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P12 mock treatment 2.87679E7 1.39E7 0.94 0.9368 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P13 mock treatment 7258850.0 -7560000.0 -0.51 -0.5077 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P14 mock treatment 5555280.0 -9260000.0 -0.62 -0.6221 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P15 mock treatment 1.38447E7 -974000.0 -0.07 -0.0654 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P16 mock treatment 2.50764E7 1.03E7 0.69 0.6889 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P17 mock treatment 1.30469E7 -1770000.0 -0.12 -0.119 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P18 mock treatment 1.42771E7 -542000.0 -0.04 -0.0364 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P19 mock treatment 1.81254E7 3310000.0 0.22 0.2221 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P20 mock treatment 8755500.0 -6060000.0 -0.41 -0.4072 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P21 mock treatment 2.26087E7 7790000.0 0.52 0.5231 1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P22 mock treatment 1.25759E7 -2240000.0 -0.15 -0.1506 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P23 mock treatment 1917150.0 -1.29E7 -0.87 -0.8664 -1.0 1053.0046 MODCInt(1053.0046) ProteinDegradationInhibition 1053.0046.Base P24 mock treatment 1.30777E7 -1740000.0 -0.12 -0.1169 -1.0