ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A01 compound treatment 17538.8 226.0 0.2 0.2038 1.0 1965040 CMLD1_000001 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A02 compound treatment 17284.6 -28.5 -0.03 -0.0257 -1.0 1965041 CMLD1_000002 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A03 compound treatment 17535.2 222.0 0.2 0.2006 1.0 1965042 CMLD1_000003 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A04 compound treatment 17620.5 307.0 0.28 0.2776 1.0 1965043 CMLD1_000004 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A05 compound treatment 17634.3 321.0 0.29 0.2901 1.0 1965044 CMLD1_000005 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A06 compound treatment 17092.3 -221.0 -0.2 -0.1993 -1.0 1965045 CMLD1_000006 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A07 compound treatment 16469.8 -843.0 -0.76 -0.7615 -1.0 1965046 CMLD1_000007 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A08 compound treatment 17107.5 -206.0 -0.19 -0.1856 -1.0 1965047 CMLD1_000008 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A09 compound treatment 17293.1 -20.0 -0.02 -0.018 -1.0 1965048 CMLD1_000009 CCCCC=C[C@@H](NC(=O)Oc1cccc(c1)C(F)(F)F)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A10 compound treatment 17411.8 98.7 0.09 0.0892 1.0 1965049 CMLD1_000010 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(OC)cc67 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A11 compound treatment 16846.5 -467.0 -0.42 -0.4213 -1.0 1965050 CMLD1_000011 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3cccs3)c4ccc(cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A12 compound treatment 18243.8 931.0 0.84 0.8405 1.0 1965051 CMLD1_000012 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A13 compound treatment 17440.2 127.0 0.11 0.1148 1.0 1965052 CMLD1_000013 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A14 compound treatment 16351.0 -962.0 -0.87 -0.8687 -1.0 1965053 CMLD1_000014 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A15 compound treatment 17418.8 106.0 0.1 0.0955 1.0 1965054 CMLD1_000015 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A16 compound treatment 17103.1 -210.0 -0.19 -0.1896 -1.0 1965055 CMLD1_000016 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A17 compound treatment 17051.9 -261.0 -0.24 -0.2358 -1.0 1965056 CMLD1_000017 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)C(C)(C)C)c2ccc(cc2)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A18 compound treatment 16589.9 -723.0 -0.65 -0.653 -1.0 1965057 CMLD1_000018 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A19 compound treatment 17539.6 227.0 0.2 0.2046 1.0 1965058 CMLD1_000019 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A20 compound treatment 18146.6 834.0 0.75 0.7527 1.0 1965059 CMLD1_000020 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A21 compound treatment 18455.7 1140.0 1.03 1.0318 1.0 1965060 CMLD1_000021 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A22 mock treatment 17025.6 -287.0 -0.26 -0.2596 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A23 mock treatment 17218.5 -94.6 -0.09 -0.0854 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 A24 mock treatment 16403.9 -909.0 -0.82 -0.821 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B01 compound treatment 17167.5 -146.0 -0.13 -0.1314 -1.0 1965061 CMLD1_000022 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B02 compound treatment 17800.1 487.0 0.44 0.4398 1.0 1965062 CMLD1_000023 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B03 compound treatment 17769.0 456.0 0.41 0.4117 1.0 1965063 CMLD1_000024 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B04 compound treatment 17294.1 -19.0 -0.02 -0.0171 -1.0 1965064 CMLD1_000025 CCOC(=O)N(CC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4)S(=O)(=O)c6ccc(C)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B05 compound treatment 16986.1 -327.0 -0.3 -0.2952 -1.0 1965065 CMLD1_000026 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B06 compound treatment 17668.7 356.0 0.32 0.3211 1.0 1965066 CMLD1_000027 CC(NP(=O)(c1ccccc1)c2ccccc2)C3(CC(=C)c4ccccc4)CC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B07 compound treatment 17064.5 -249.0 -0.22 -0.2244 -1.0 1965067 CMLD1_000028 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B08 compound treatment 17705.2 392.0 0.35 0.3541 1.0 1965068 CMLD1_000029 COC(=O)C1(C)NCC2=C(C)C(=O)C(C)C2=C1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B09 compound treatment 17243.8 -69.3 -0.06 -0.0625 -1.0 1965069 CMLD1_000030 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B10 compound treatment 17980.1 667.0 0.6 0.6023 1.0 1965070 CMLD1_000031 COC(=O)C1(Cc2ccccc2)NCC3=C(C(C)C)C(=O)C(C)C3=C1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B11 compound treatment 17733.6 421.0 0.38 0.3798 1.0 1965071 CMLD1_000032 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B12 compound treatment 18078.9 766.0 0.69 0.6916 1.0 1965072 CMLD1_000033 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCc5ccc(Cl)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B13 compound treatment 18155.0 842.0 0.76 0.7603 1.0 1965073 CMLD1_000034 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B14 compound treatment 17704.3 391.0 0.35 0.3533 1.0 1965074 CMLD1_000035 COc1ccc(COC2OC[C@]3(C)[C@@H]4[C@H]2CCC5C(CO)C(CO)[C@@H](C)C(=C54)CN3C(=O)OC(C)(C)C)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B15 compound treatment 17603.9 291.0 0.26 0.2626 1.0 1965075 CMLD1_000036 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B16 compound treatment 17121.3 -192.0 -0.17 -0.1732 -1.0 1965076 CMLD1_000037 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(F)cc5)C=C21)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B17 compound treatment 17760.3 447.0 0.4 0.4039 1.0 1965077 CMLD1_000038 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B18 compound treatment 17241.9 -71.2 -0.06 -0.0643 -1.0 1965078 CMLD1_000039 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B19 compound treatment 16989.2 -324.0 -0.29 -0.2924 -1.0 1965079 CMLD1_000040 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B20 compound treatment 17859.4 546.0 0.49 0.4934 1.0 1965080 CMLD1_000041 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B21 compound treatment 17493.9 181.0 0.16 0.1633 1.0 1965081 CMLD1_000042 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B22 mock treatment 17962.7 650.0 0.59 0.5866 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B23 mock treatment 16930.0 -383.0 -0.35 -0.3459 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 B24 mock treatment 16119.8 -1190.0 -1.08 -1.0775 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C01 compound treatment 17007.8 -305.0 -0.28 -0.2756 -1.0 1965082 CMLD1_000043 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC1(CCC2CC1=O)C2(C)C)c3ccc(cc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C02 compound treatment 15780.1 -1530.0 -1.38 -1.3843 -1.0 1965083 CMLD1_000044 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C03 compound treatment 16994.8 -318.0 -0.29 -0.2874 -1.0 1965084 CMLD1_000045 CCCC=C(CCC)[C@@H](NC(=O)CCc1ccccc1)c2ccc(cc2)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C04 compound treatment 17401.5 88.4 0.08 0.0799 1.0 1965085 CMLD1_000046 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C05 compound treatment 17610.1 297.0 0.27 0.2682 1.0 1965086 CMLD1_000047 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C06 compound treatment 17257.4 -55.7 -0.05 -0.0503 -1.0 1965087 CMLD1_000048 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C07 compound treatment 16421.0 -892.0 -0.81 -0.8055 -1.0 1965088 CMLD1_000049 CCCCC=C[C@@H](NC(=O)CCc1ccccc1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C08 compound treatment 17379.2 66.1 0.06 0.0597 1.0 1965089 CMLD1_000050 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(C)onc6c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C09 compound treatment 17093.5 -220.0 -0.2 -0.1983 -1.0 1965090 CMLD1_000051 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C10 compound treatment 16078.2 -1230.0 -1.12 -1.1151 -1.0 1965091 CMLD1_000052 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C11 compound treatment 16985.1 -328.0 -0.3 -0.2961 -1.0 1965092 CMLD1_000053 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccccc3)c4ccc(cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C12 compound treatment 17556.5 243.0 0.22 0.2198 1.0 1965093 CMLD1_000054 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C13 compound treatment 17616.6 304.0 0.27 0.2741 1.0 1965094 CMLD1_000055 CCCCC=C[C@@H](NC(=O)c1ccccc1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C14 compound treatment 17012.5 -301.0 -0.27 -0.2714 -1.0 1965095 CMLD1_000056 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C15 compound treatment 17749.8 437.0 0.39 0.3944 1.0 1965096 CMLD1_000057 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4ccc(cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C16 compound treatment 16675.0 -638.0 -0.58 -0.5762 -1.0 1965097 CMLD1_000058 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C17 compound treatment 17904.6 592.0 0.53 0.5342 1.0 1965098 CMLD1_000059 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NS(=O)(=O)c3cccc4cccnc34)c5ccc(cc5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C18 compound treatment 17319.1 6.04 0.01 0.0055 1.0 1965099 CMLD1_000060 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(OC)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C19 compound treatment 16618.2 -695.0 -0.63 -0.6275 -1.0 1965100 CMLD1_000061 CC(C)(C)C(=O)N[C@@H](c1ccc(Cl)cc1)[C@]2(C)C[C@H]2C3CCCCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C20 compound treatment 17529.3 216.0 0.2 0.1953 1.0 1965101 CMLD1_000062 CCCCC=C[C@@H](NC(=O)OCC#C)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C21 compound treatment 17809.6 497.0 0.45 0.4484 1.0 1965060 CMLD1_000063 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C22 mock treatment 17235.7 -77.4 -0.07 -0.0699 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C23 mock treatment 17839.9 527.0 0.48 0.4757 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 C24 mock treatment 17343.4 30.3 0.03 0.0274 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D01 compound treatment 17631.7 319.0 0.29 0.2877 1.0 1965102 CMLD1_000064 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D02 compound treatment 17728.1 415.0 0.37 0.3748 1.0 1965103 CMLD1_000065 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D03 compound treatment 18086.8 774.0 0.7 0.6987 1.0 1965104 CMLD1_000066 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D04 compound treatment 18549.4 1240.0 1.12 1.1164 1.0 1965105 CMLD1_000067 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D05 compound treatment 16337.1 -976.0 -0.88 -0.8813 -1.0 1965106 CMLD1_000068 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D06 compound treatment 17804.4 491.0 0.44 0.4437 1.0 1965107 CMLD1_000069 CC(=O)N1CC2(CC2)CC1c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D07 compound treatment 17733.0 420.0 0.38 0.3792 1.0 1965108 CMLD1_000070 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D08 compound treatment 18243.5 930.0 0.84 0.8402 1.0 1965109 CMLD1_000071 COC(=O)C1(C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D09 compound treatment 18666.0 1350.0 1.22 1.2217 1.0 1965110 CMLD1_000072 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCn7cc(nc7C)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D10 compound treatment 17902.1 589.0 0.53 0.5319 1.0 1965111 CMLD1_000073 COC(=O)C1(Cc2ccccc2)NCC3=C(C(=O)C(C)C3=C1)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D11 compound treatment 16863.8 -449.0 -0.41 -0.4057 -1.0 1965112 CMLD1_000074 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D12 compound treatment 18282.3 969.0 0.88 0.8752 1.0 1965113 CMLD1_000075 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccco5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D13 compound treatment 17500.6 188.0 0.17 0.1694 1.0 1965057 CMLD1_000076 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D14 compound treatment 17888.7 576.0 0.52 0.5198 1.0 1965114 CMLD1_000077 C[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D15 compound treatment 17778.0 465.0 0.42 0.4198 1.0 1965115 CMLD1_000078 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D16 compound treatment 17660.5 347.0 0.31 0.3137 1.0 1965116 CMLD1_000079 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(F)cc6)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D17 compound treatment 17868.1 555.0 0.5 0.5012 1.0 1965117 CMLD1_000080 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D18 compound treatment 17503.4 190.0 0.17 0.1719 1.0 1965118 CMLD1_000081 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D19 compound treatment 17900.2 587.0 0.53 0.5302 1.0 1965119 CMLD1_000082 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D20 compound treatment 17682.3 369.0 0.33 0.3334 1.0 1965120 CMLD1_000083 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D21 compound treatment 16656.4 -657.0 -0.59 -0.593 -1.0 1965121 CMLD1_000084 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D22 mock treatment 17721.0 408.0 0.37 0.3684 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D23 mock treatment 17626.5 313.0 0.28 0.283 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 D24 mock treatment 18079.6 767.0 0.69 0.6922 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E01 compound treatment 16768.1 -545.0 -0.49 -0.4921 -1.0 1965122 CMLD1_000085 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E02 compound treatment 17416.8 104.0 0.09 0.0937 1.0 1965123 CMLD1_000086 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E03 compound treatment 16895.3 -418.0 -0.38 -0.3772 -1.0 1965124 CMLD1_000087 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E04 compound treatment 18647.0 1330.0 1.2 1.2046 1.0 1965125 CMLD1_000088 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E05 compound treatment 17139.5 -174.0 -0.16 -0.1567 -1.0 1965126 CMLD1_000089 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E06 compound treatment 17651.0 338.0 0.31 0.3052 1.0 1965127 CMLD1_000090 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E07 compound treatment 17175.9 -137.0 -0.12 -0.1239 -1.0 1965128 CMLD1_000091 CCCCC=C[C@@H](NC(=O)C(C)(C)C)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E08 compound treatment 17599.8 287.0 0.26 0.2589 1.0 1965129 CMLD1_000092 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E09 compound treatment 16488.3 -825.0 -0.74 -0.7448 -1.0 1965130 CMLD1_000093 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E10 compound treatment 16447.6 -865.0 -0.78 -0.7815 -1.0 1965131 CMLD1_000094 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E11 compound treatment 17080.2 -233.0 -0.21 -0.2103 -1.0 1965060 CMLD1_000095 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E12 compound treatment 17384.3 71.2 0.06 0.0643 1.0 1965132 CMLD1_000096 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E13 compound treatment 17183.4 -130.0 -0.12 -0.1171 -1.0 1965133 CMLD1_000097 CCCCC=C[C@@H](NC(=O)OCc1ccccc1Cl)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E14 compound treatment 18341.0 1030.0 0.93 0.9282 1.0 1965134 CMLD1_000098 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E15 compound treatment 17885.0 572.0 0.52 0.5165 1.0 1965135 CMLD1_000099 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E16 compound treatment 17591.8 279.0 0.25 0.2517 1.0 1965136 CMLD1_000100 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E17 compound treatment 16516.1 -797.0 -0.72 -0.7197 -1.0 1965137 CMLD1_000101 CC(=CC1CCCCC1)[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E18 compound treatment 16576.0 -737.0 -0.67 -0.6656 -1.0 1965138 CMLD1_000102 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E19 compound treatment 18266.8 954.0 0.86 0.8612 1.0 1965139 CMLD1_000103 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccc(cc3)c4ccccc4)c5ccc(Cl)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E20 compound treatment 18402.4 1090.0 0.98 0.9837 1.0 1965140 CMLD1_000104 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E21 compound treatment 16639.4 -674.0 -0.61 -0.6083 -1.0 1965141 CMLD1_000105 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccccc2)c3cccc(Cl)c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E22 mock treatment 16825.4 -488.0 -0.44 -0.4404 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E23 mock treatment 17650.9 338.0 0.31 0.3051 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 E24 mock treatment 18794.2 1480.0 1.34 1.3375 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F01 compound treatment 17041.7 -271.0 -0.25 -0.245 -1.0 1965142 CMLD1_000106 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CCOCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F02 compound treatment 17178.9 -134.0 -0.12 -0.1211 -1.0 1965143 CMLD1_000107 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F03 compound treatment 17625.1 312.0 0.28 0.2818 1.0 1965144 CMLD1_000108 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F04 compound treatment 18185.2 872.0 0.79 0.7876 1.0 1965145 CMLD1_000109 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5cccc(OC)c5)CC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F05 compound treatment 17812.6 500.0 0.45 0.4511 1.0 1965146 CMLD1_000110 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F06 compound treatment 17986.3 673.0 0.61 0.6079 1.0 1965147 CMLD1_000111 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F07 compound treatment 17379.8 66.7 0.06 0.0603 1.0 1965148 CMLD1_000112 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F08 compound treatment 18922.2 1610.0 1.45 1.4531 1.0 1965149 CMLD1_000113 CCCCCC1=C2CNC(C)(C=C2C(C)C1=O)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F09 compound treatment 17340.0 26.9 0.02 0.0243 1.0 1965150 CMLD1_000114 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F10 compound treatment 18250.4 937.0 0.85 0.8464 1.0 1965151 CMLD1_000115 CCCCCC1=C2CNC(Cc3ccccc3)(C=C2C(C)C1=O)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F11 compound treatment 17639.9 327.0 0.3 0.2951 1.0 1965152 CMLD1_000116 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F12 compound treatment 17751.8 439.0 0.4 0.3962 1.0 1965153 CMLD1_000117 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F13 compound treatment 17805.2 492.0 0.44 0.4444 1.0 1965154 CMLD1_000118 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F14 compound treatment 18236.0 923.0 0.83 0.8334 1.0 1965155 CMLD1_000119 C[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F15 compound treatment 18063.7 751.0 0.68 0.6778 1.0 1965156 CMLD1_000120 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F16 compound treatment 17315.7 2.64 0.0 0.0024 1.0 1965157 CMLD1_000121 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(cc5)C(F)(F)F)C=C21)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F17 compound treatment 18465.7 1150.0 1.04 1.0408 1.0 1965158 CMLD1_000122 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F18 compound treatment 17903.7 591.0 0.53 0.5334 1.0 1965150 CMLD1_000123 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F19 compound treatment 18229.3 916.0 0.83 0.8274 1.0 1965159 CMLD1_000124 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F20 compound treatment 18507.6 1190.0 1.08 1.0787 1.0 1965160 CMLD1_000125 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F21 compound treatment 17648.5 335.0 0.3 0.3029 1.0 1965161 CMLD1_000126 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F22 mock treatment 17744.1 431.0 0.39 0.3892 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F23 mock treatment 17611.6 299.0 0.27 0.2696 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 F24 mock treatment 18431.3 1120.0 1.01 1.0098 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G01 compound treatment 17506.6 194.0 0.17 0.1748 1.0 1965162 CMLD1_000127 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G02 compound treatment 17200.9 -112.0 -0.1 -0.1013 -1.0 1965163 CMLD1_000128 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G03 compound treatment 16845.0 -468.0 -0.42 -0.4227 -1.0 1965164 CMLD1_000129 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccccc1)c2ccc(cc2)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G04 compound treatment 17705.3 392.0 0.35 0.3542 1.0 1965165 CMLD1_000130 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G05 compound treatment 17765.1 452.0 0.41 0.4082 1.0 1965166 CMLD1_000131 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G06 compound treatment 18428.0 1110.0 1.01 1.0068 1.0 1965167 CMLD1_000132 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G07 compound treatment 15794.9 -1520.0 -1.37 -1.3709 -1.0 1965168 CMLD1_000133 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G08 compound treatment 18015.7 703.0 0.63 0.6345 1.0 1965169 CMLD1_000134 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccccc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G09 compound treatment 16922.6 -390.0 -0.35 -0.3526 -1.0 1965170 CMLD1_000135 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G10 compound treatment 16352.2 -961.0 -0.87 -0.8677 -1.0 1965171 CMLD1_000136 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)c(F)c(F)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G11 compound treatment 16732.8 -580.0 -0.52 -0.524 -1.0 1965172 CMLD1_000137 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(Cl)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G12 compound treatment 17897.8 585.0 0.53 0.528 1.0 1965173 CMLD1_000138 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G13 compound treatment 17417.6 105.0 0.09 0.0944 1.0 1965174 CMLD1_000139 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G14 compound treatment 17729.3 416.0 0.38 0.3759 1.0 1965175 CMLD1_000140 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G15 compound treatment 17815.6 503.0 0.45 0.4538 1.0 1965176 CMLD1_000141 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G16 compound treatment 18101.2 788.0 0.71 0.7117 1.0 1965177 CMLD1_000142 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G17 compound treatment 17864.6 552.0 0.5 0.498 1.0 1965178 CMLD1_000143 CC(=CC1CCCCC1)[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G18 compound treatment 18020.7 708.0 0.64 0.639 1.0 1965179 CMLD1_000144 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G19 compound treatment 17913.5 600.0 0.54 0.5422 1.0 1965180 CMLD1_000145 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G20 compound treatment 17225.3 -87.8 -0.08 -0.0792 -1.0 1965181 CMLD1_000146 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G21 compound treatment 16167.4 -1150.0 -1.03 -1.0345 -1.0 1965182 CMLD1_000147 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G22 mock treatment 17563.6 251.0 0.23 0.2262 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G23 mock treatment 16372.1 -941.0 -0.85 -0.8497 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 G24 mock treatment 16946.2 -367.0 -0.33 -0.3313 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H01 compound treatment 17785.5 472.0 0.43 0.4266 1.0 1965183 CMLD1_000148 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H02 compound treatment 17927.1 614.0 0.55 0.5545 1.0 1965184 CMLD1_000149 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H03 compound treatment 17856.6 544.0 0.49 0.4908 1.0 1965185 CMLD1_000150 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H04 compound treatment 17565.2 252.0 0.23 0.2277 1.0 1965186 CMLD1_000151 CCCC[C@H]1C[C@@H]1[C@@H]2N(C[C@](O)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H05 compound treatment 17766.3 453.0 0.41 0.4093 1.0 1965187 CMLD1_000152 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H06 compound treatment 17690.4 377.0 0.34 0.3407 1.0 1965147 CMLD1_000153 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H07 compound treatment 18057.2 744.0 0.67 0.672 1.0 1965188 CMLD1_000154 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H08 compound treatment 18320.0 1010.0 0.91 0.9093 1.0 1965189 CMLD1_000155 CCCC1(NCC2=C(C)C(=O)C(C)C2=C1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H09 compound treatment 17799.7 487.0 0.44 0.4394 1.0 1965190 CMLD1_000156 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H10 compound treatment 18322.3 1010.0 0.91 0.9114 1.0 1965191 CMLD1_000157 COC(=O)C1(CC(C)C)NCC2=C(C)C(=O)C(C)C2=C1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H11 compound treatment 17893.4 580.0 0.52 0.5241 1.0 1965192 CMLD1_000158 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H12 compound treatment 18532.5 1220.0 1.1 1.1012 1.0 1965193 CMLD1_000159 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H13 compound treatment 16909.6 -403.0 -0.36 -0.3643 -1.0 1965194 CMLD1_000160 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H14 compound treatment 17799.2 486.0 0.44 0.439 1.0 1965195 CMLD1_000161 C[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H15 compound treatment 17779.7 467.0 0.42 0.4214 1.0 1965196 CMLD1_000162 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H16 compound treatment 17828.0 515.0 0.46 0.465 1.0 1965197 CMLD1_000163 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(cc6)C(F)(F)F)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H17 compound treatment 18647.9 1330.0 1.21 1.2054 1.0 1965198 CMLD1_000164 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N6CCCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H18 compound treatment 17315.4 2.34 0.0 0.0021 1.0 1965199 CMLD1_000165 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H19 compound treatment 17871.3 558.0 0.5 0.5041 1.0 1965200 CMLD1_000166 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H20 compound treatment 17832.0 519.0 0.47 0.4686 1.0 1965201 CMLD1_000167 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H21 compound treatment 18034.7 722.0 0.65 0.6516 1.0 1965202 CMLD1_000168 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H22 mock treatment 17824.3 511.0 0.46 0.4617 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H23 mock treatment 17952.8 640.0 0.58 0.5777 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 H24 mock treatment 17140.3 -173.0 -0.16 -0.156 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I01 compound treatment 17008.3 -305.0 -0.28 -0.2752 -1.0 1965203 CMLD1_000169 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I02 compound treatment 17406.3 93.2 0.08 0.0842 1.0 1965204 CMLD1_000170 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I03 compound treatment 17287.3 -25.8 -0.02 -0.0233 -1.0 1965205 CMLD1_000171 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I04 compound treatment 17943.0 630.0 0.57 0.5688 1.0 1965206 CMLD1_000172 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I05 compound treatment 17124.9 -188.0 -0.17 -0.1699 -1.0 1965207 CMLD1_000173 CCCC=C(CCC)[C@@H](NC(=O)c1ccco1)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I06 compound treatment 17913.1 600.0 0.54 0.5418 1.0 1965208 CMLD1_000174 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I07 compound treatment 16024.1 -1290.0 -1.16 -1.1639 -1.0 1965209 CMLD1_000175 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I08 compound treatment 17852.5 539.0 0.49 0.4871 1.0 1965210 CMLD1_000176 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I09 compound treatment 17923.3 610.0 0.55 0.5511 1.0 1965211 CMLD1_000177 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I10 compound treatment 17453.9 141.0 0.13 0.1272 1.0 1965212 CMLD1_000178 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I11 compound treatment 16662.3 -651.0 -0.59 -0.5876 -1.0 1965213 CMLD1_000179 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(Cl)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I12 compound treatment 17582.6 270.0 0.24 0.2434 1.0 1965214 CMLD1_000180 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I13 compound treatment 17248.5 -64.6 -0.06 -0.0583 -1.0 1965215 CMLD1_000181 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I14 compound treatment 17519.0 206.0 0.19 0.186 1.0 1965216 CMLD1_000182 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I15 compound treatment 17335.7 22.6 0.02 0.0204 1.0 1965217 CMLD1_000183 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I16 compound treatment 17993.2 680.0 0.61 0.6142 1.0 1965218 CMLD1_000184 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I17 compound treatment 17176.7 -136.0 -0.12 -0.1231 -1.0 1965219 CMLD1_000185 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccccc2)[C@]3(C)C[C@H]3C4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I18 compound treatment 17954.3 641.0 0.58 0.579 1.0 1965220 CMLD1_000186 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I19 compound treatment 17716.5 403.0 0.36 0.3643 1.0 1965221 CMLD1_000187 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccccc3C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I20 compound treatment 18262.9 950.0 0.86 0.8577 1.0 1965222 CMLD1_000188 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I21 compound treatment 15365.3 -1950.0 -1.76 -1.7588 -1.0 1965223 CMLD1_000189 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CC6CC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I22 mock treatment 17505.3 192.0 0.17 0.1736 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I23 mock treatment 17395.9 82.8 0.07 0.0748 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 I24 mock treatment 16955.8 -357.0 -0.32 -0.3226 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J01 compound treatment 17630.3 317.0 0.29 0.2865 1.0 1965224 CMLD1_000190 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J02 compound treatment 17132.4 -181.0 -0.16 -0.1631 -1.0 1965225 CMLD1_000191 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J03 compound treatment 17438.7 126.0 0.11 0.1135 1.0 1965226 CMLD1_000192 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J04 compound treatment 17882.6 570.0 0.51 0.5143 1.0 1965227 CMLD1_000193 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@](CO)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J05 compound treatment 17864.4 551.0 0.5 0.4979 1.0 1965228 CMLD1_000194 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J06 compound treatment 17991.9 679.0 0.61 0.613 1.0 1965229 CMLD1_000195 OC1(CN(CC2(CC2)C1)P(=O)(c3ccccc3)c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J07 compound treatment 16504.3 -809.0 -0.73 -0.7303 -1.0 1965230 CMLD1_000196 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J08 compound treatment 17837.2 524.0 0.47 0.4733 1.0 1965231 CMLD1_000197 CCCC1(NCC2=C(C(C)C)C(=O)C(C)C2=C1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J09 compound treatment 17390.6 77.5 0.07 0.07 1.0 1965232 CMLD1_000198 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J10 compound treatment 18060.7 748.0 0.68 0.6751 1.0 1965233 CMLD1_000199 COC(=O)C1(CC(C)C)NCC2=C(C(C)C)C(=O)C(C)C2=C1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J11 compound treatment 17857.2 544.0 0.49 0.4914 1.0 1965234 CMLD1_000200 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J12 compound treatment 18266.7 954.0 0.86 0.8611 1.0 1965235 CMLD1_000201 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cccc(Cl)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J13 compound treatment 17536.9 224.0 0.2 0.2021 1.0 1965236 CMLD1_000202 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J14 compound treatment 17639.0 326.0 0.29 0.2943 1.0 1965237 CMLD1_000203 CC[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J15 compound treatment 17497.4 184.0 0.17 0.1665 1.0 1965238 CMLD1_000204 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J16 compound treatment 17830.4 517.0 0.47 0.4672 1.0 1965239 CMLD1_000205 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J17 compound treatment 17587.7 275.0 0.25 0.248 1.0 1965240 CMLD1_000206 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J18 compound treatment 17531.3 218.0 0.2 0.1971 1.0 1965241 CMLD1_000207 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J19 compound treatment 17586.4 273.0 0.25 0.2468 1.0 1965242 CMLD1_000208 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J20 compound treatment 18013.8 701.0 0.63 0.6328 1.0 1965243 CMLD1_000209 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J21 compound treatment 16245.9 -1070.0 -0.96 -0.9637 -1.0 1965244 CMLD1_000210 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J22 mock treatment 17622.0 309.0 0.28 0.279 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J23 mock treatment 17739.6 427.0 0.39 0.3852 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 J24 mock treatment 17794.1 481.0 0.43 0.4344 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K01 compound treatment 17204.1 -109.0 -0.1 -0.0984 -1.0 1965245 CMLD1_000211 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K02 compound treatment 16661.1 -652.0 -0.59 -0.5887 -1.0 1965246 CMLD1_000212 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K03 compound treatment 17655.1 342.0 0.31 0.3089 1.0 1965247 CMLD1_000213 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K04 compound treatment 17061.5 -252.0 -0.23 -0.2272 -1.0 1965248 CMLD1_000214 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K05 compound treatment 16231.1 -1080.0 -0.98 -0.977 -1.0 1965249 CMLD1_000215 CCCC=C(CCC)[C@@H](NC(=O)C(C)(C)C)c1ccc(cc1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K06 compound treatment 17506.7 194.0 0.17 0.1749 1.0 1965250 CMLD1_000216 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K07 compound treatment 17596.8 284.0 0.26 0.2562 1.0 1965251 CMLD1_000217 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K08 compound treatment 16714.4 -599.0 -0.54 -0.5406 -1.0 1965252 CMLD1_000218 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K09 compound treatment 16970.7 -342.0 -0.31 -0.3092 -1.0 1965253 CMLD1_000219 CCCC=C(CCC)[C@@H](NC(=O)Cc1ccccc1)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K10 compound treatment 17173.4 -140.0 -0.13 -0.1261 -1.0 1965254 CMLD1_000220 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K11 compound treatment 16210.7 -1100.0 -1.0 -0.9954 -1.0 1965255 CMLD1_000221 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K12 compound treatment 17754.7 442.0 0.4 0.3988 1.0 1965256 CMLD1_000222 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K13 compound treatment 17787.6 475.0 0.43 0.4285 1.0 1965257 CMLD1_000223 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K14 compound treatment 17936.3 623.0 0.56 0.5628 1.0 1965258 CMLD1_000224 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K15 compound treatment 17813.5 500.0 0.45 0.4519 1.0 1965259 CMLD1_000225 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K16 compound treatment 17639.8 327.0 0.3 0.2951 1.0 1965260 CMLD1_000226 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K17 compound treatment 17059.1 -254.0 -0.23 -0.2293 -1.0 1965261 CMLD1_000227 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccco2)[C@]3(C)C[C@H]3C4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K18 compound treatment 17794.3 481.0 0.43 0.4346 1.0 1965262 CMLD1_000228 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K19 compound treatment 17662.8 350.0 0.32 0.3158 1.0 1965263 CMLD1_000229 CCCC[C@@H]1C[C@H]1[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K20 compound treatment 17820.8 508.0 0.46 0.4585 1.0 1965264 CMLD1_000230 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K21 compound treatment 17281.4 -31.7 -0.03 -0.0286 -1.0 1965265 CMLD1_000231 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K22 mock treatment 16225.4 -1090.0 -0.98 -0.9822 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K23 mock treatment 17524.6 212.0 0.19 0.191 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 K24 mock treatment 16363.2 -950.0 -0.86 -0.8577 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L01 compound treatment 18323.5 1010.0 0.91 0.9124 1.0 1965266 CMLD1_000232 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L02 compound treatment 17346.7 33.6 0.03 0.0304 1.0 1965267 CMLD1_000233 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L03 compound treatment 17870.9 558.0 0.5 0.5037 1.0 1965268 CMLD1_000234 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L04 compound treatment 18019.3 706.0 0.64 0.6377 1.0 1965269 CMLD1_000235 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@H](CC32CC3)c4cccc(OC)c4)C(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L05 compound treatment 17205.3 -108.0 -0.1 -0.0973 -1.0 1965270 CMLD1_000236 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7cc8ccccc8[nH]7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L06 compound treatment 16840.4 -473.0 -0.43 -0.4268 -1.0 1965271 CMLD1_000237 C=C(CC1(CNP(=O)(c2ccccc2)c3ccccc3)CC1)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L07 compound treatment 16839.4 -474.0 -0.43 -0.4277 -1.0 1965272 CMLD1_000238 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L08 compound treatment 17006.0 -307.0 -0.28 -0.2773 -1.0 1965273 CMLD1_000239 CCCC1(NCC2=C(C(=O)C(C)C2=C1)c3ccccc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L09 compound treatment 17611.5 298.0 0.27 0.2695 1.0 1965274 CMLD1_000240 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L10 compound treatment 16063.5 -1250.0 -1.13 -1.1284 -1.0 1965275 CMLD1_000241 COC(=O)C1(CC(C)C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L11 compound treatment 16484.9 -828.0 -0.75 -0.7478 -1.0 1965276 CMLD1_000242 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L12 compound treatment 17336.6 23.5 0.02 0.0213 1.0 1965277 CMLD1_000243 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cc(F)cc(F)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L13 compound treatment 17228.8 -84.3 -0.08 -0.0761 -1.0 1965278 CMLD1_000244 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L14 compound treatment 18112.1 799.0 0.72 0.7215 1.0 1965279 CMLD1_000245 CC[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L15 compound treatment 18174.1 861.0 0.78 0.7775 1.0 1965280 CMLD1_000246 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L16 compound treatment 18243.7 931.0 0.84 0.8404 1.0 1965281 CMLD1_000247 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccccc6)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L17 compound treatment 18253.0 940.0 0.85 0.8488 1.0 1965282 CMLD1_000248 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSC(=N)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L18 compound treatment 18491.8 1180.0 1.06 1.0644 1.0 1965079 CMLD1_000249 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L19 compound treatment 17975.0 662.0 0.6 0.5977 1.0 1965283 CMLD1_000250 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L20 compound treatment 17373.0 59.9 0.05 0.0541 1.0 1965284 CMLD1_000251 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L21 compound treatment 16947.6 -365.0 -0.33 -0.33 -1.0 1965285 CMLD1_000252 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L22 mock treatment 17186.6 -126.0 -0.11 -0.1142 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L23 mock treatment 17175.8 -137.0 -0.12 -0.1239 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 L24 mock treatment 17316.3 3.24 0.0 0.0029 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M01 compound treatment 16921.1 -392.0 -0.35 -0.3539 -1.0 1965286 CMLD1_000253 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M02 compound treatment 17006.2 -307.0 -0.28 -0.2771 -1.0 1965287 CMLD1_000254 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M03 compound treatment 17153.8 -159.0 -0.14 -0.1438 -1.0 1965288 CMLD1_000255 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M04 compound treatment 16966.5 -347.0 -0.31 -0.3129 -1.0 1965289 CMLD1_000256 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(C)onc7c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M05 compound treatment 17185.8 -127.0 -0.11 -0.1149 -1.0 1965290 CMLD1_000257 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M06 compound treatment 17646.5 333.0 0.3 0.3011 1.0 1965090 CMLD1_000258 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M07 compound treatment 16537.8 -775.0 -0.7 -0.7001 -1.0 1965291 CMLD1_000259 CCCCC=C[C@@H](NC(=O)c1ccco1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M08 compound treatment 16300.3 -1010.0 -0.91 -0.9145 -1.0 1965292 CMLD1_000260 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M09 compound treatment 17532.8 220.0 0.2 0.1984 1.0 1965293 CMLD1_000261 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)OCc2ccccc2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M10 compound treatment 17064.2 -249.0 -0.22 -0.2247 -1.0 1965294 CMLD1_000262 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCCNc6ccc(cc6Cl)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M11 compound treatment 16829.4 -484.0 -0.44 -0.4367 -1.0 1965295 CMLD1_000263 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(Cl)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M12 compound treatment 17826.2 513.0 0.46 0.4634 1.0 1965296 CMLD1_000264 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M13 compound treatment 17551.7 239.0 0.22 0.2155 1.0 1965297 CMLD1_000265 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M14 compound treatment 17378.5 65.4 0.06 0.0591 1.0 1965298 CMLD1_000266 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M15 compound treatment 17522.0 209.0 0.19 0.1887 1.0 1965299 CMLD1_000267 CCCC[C@@H]1C[C@H]1[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M16 compound treatment 17400.2 87.1 0.08 0.0787 1.0 1965300 CMLD1_000268 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(O)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M17 compound treatment 17997.6 685.0 0.62 0.6181 1.0 1965301 CMLD1_000269 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(Cl)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M18 compound treatment 17403.9 90.8 0.08 0.082 1.0 1965302 CMLD1_000270 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M19 compound treatment 17689.9 377.0 0.34 0.3403 1.0 1965303 CMLD1_000271 CCCC=C(CCC)[C@@H](NC(=O)Oc1ccc(F)cc1)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M20 compound treatment 17099.6 -213.0 -0.19 -0.1928 -1.0 1965304 CMLD1_000272 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M21 mock treatment 17696.5 383.0 0.35 0.3463 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M22 mock treatment 17320.3 7.24 0.01 0.0065 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M23 mock treatment 17287.8 -25.3 -0.02 -0.0228 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 M24 mock treatment 16680.0 -633.0 -0.57 -0.5717 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N01 compound treatment 16873.9 -439.0 -0.4 -0.3966 -1.0 1965305 CMLD1_000273 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N02 compound treatment 16387.3 -926.0 -0.84 -0.836 -1.0 1965306 CMLD1_000274 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N03 compound treatment 17650.1 337.0 0.3 0.3044 1.0 1965307 CMLD1_000275 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N04 compound treatment 16174.2 -1140.0 -1.03 -1.0284 -1.0 1965308 CMLD1_000276 COC(=O)c1ccc(C#CC(NP(=O)(c2ccccc2)c3ccccc3)c4ccccc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N05 compound treatment 16844.6 -468.0 -0.42 -0.423 -1.0 1965309 CMLD1_000277 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N06 compound treatment 17082.7 -230.0 -0.21 -0.208 -1.0 1965310 CMLD1_000278 O=P(NCC1(CC2(CO2)c3ccccc3)CC1)(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N07 compound treatment 17216.9 -96.2 -0.09 -0.0868 -1.0 1965311 CMLD1_000279 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N08 compound treatment 17829.0 516.0 0.47 0.4659 1.0 1965312 CMLD1_000280 CCCCCC1=C2CNC(CCC)(C=C2C(C)C1=O)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N09 compound treatment 17850.6 538.0 0.49 0.4854 1.0 1965313 CMLD1_000281 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CCOCC7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N10 compound treatment 18260.8 948.0 0.86 0.8558 1.0 1965314 CMLD1_000282 CCCCCC1=C2CNC(CC(C)C)(C=C2C(C)C1=O)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N11 compound treatment 17004.2 -309.0 -0.28 -0.2789 -1.0 1965315 CMLD1_000283 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N12 compound treatment 17254.2 -58.9 -0.05 -0.0531 -1.0 1965316 CMLD1_000284 COC1OC[C@]2(C)[C@@H]3[C@H]1CCC4C(CO)C(CO)[C@@H](C)C(=C43)CN2C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N13 compound treatment 16551.8 -761.0 -0.69 -0.6874 -1.0 1965317 CMLD1_000285 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N14 compound treatment 17553.5 240.0 0.22 0.2171 1.0 1965318 CMLD1_000286 CC[C@@H]1C(COC)C(COC)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N15 compound treatment 17391.3 78.2 0.07 0.0707 1.0 1965319 CMLD1_000287 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N16 compound treatment 17446.7 134.0 0.12 0.1207 1.0 1965320 CMLD1_000288 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccccc5)C=C21)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N17 compound treatment 16970.3 -343.0 -0.31 -0.3095 -1.0 1965321 CMLD1_000289 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N18 compound treatment 18233.8 921.0 0.83 0.8314 1.0 1965322 CMLD1_000290 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N19 compound treatment 17598.7 286.0 0.26 0.2579 1.0 1965323 CMLD1_000291 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(O)cc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N20 compound treatment 17842.8 530.0 0.48 0.4784 1.0 1965324 CMLD1_000292 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N21 mock treatment 17475.1 162.0 0.15 0.1463 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N22 mock treatment 17267.3 -45.8 -0.04 -0.0413 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N23 mock treatment 17433.4 120.0 0.11 0.1087 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 N24 mock treatment 18095.1 782.0 0.71 0.7062 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O01 compound treatment 16650.7 -662.0 -0.6 -0.5981 -1.0 1965325 CMLD1_000293 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccc(cc1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O02 compound treatment 16552.3 -761.0 -0.69 -0.687 -1.0 1965326 CMLD1_000294 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O03 compound treatment 17760.5 447.0 0.4 0.404 1.0 1965327 CMLD1_000295 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O04 compound treatment 16292.7 -1020.0 -0.92 -0.9214 -1.0 1965268 CMLD1_000296 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O05 compound treatment 17322.9 9.84 0.01 0.0089 1.0 1965328 CMLD1_000297 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O06 compound treatment 16555.6 -757.0 -0.68 -0.684 -1.0 1965329 CMLD1_000298 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O07 compound treatment 16543.7 -769.0 -0.69 -0.6947 -1.0 1965330 CMLD1_000299 CCCCC=C[C@@H](NC(=O)c1cccs1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O08 compound treatment 17045.8 -267.0 -0.24 -0.2413 -1.0 1965331 CMLD1_000300 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O09 compound treatment 17753.0 440.0 0.4 0.3973 1.0 1965332 CMLD1_000301 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O10 compound treatment 16160.3 -1150.0 -1.04 -1.0409 -1.0 1965333 CMLD1_000302 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O11 compound treatment 16444.5 -869.0 -0.78 -0.7843 -1.0 1965334 CMLD1_000303 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O12 compound treatment 16347.6 -965.0 -0.87 -0.8718 -1.0 1965335 CMLD1_000304 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O13 compound treatment 16713.8 -599.0 -0.54 -0.5411 -1.0 1965336 CMLD1_000305 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O14 compound treatment 16063.4 -1250.0 -1.13 -1.1284 -1.0 1965337 CMLD1_000306 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O15 compound treatment 17062.7 -250.0 -0.23 -0.2261 -1.0 1965338 CMLD1_000307 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O16 compound treatment 17243.7 -69.4 -0.06 -0.0626 -1.0 1965339 CMLD1_000308 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O17 compound treatment 17579.9 267.0 0.24 0.241 1.0 1965340 CMLD1_000309 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O18 compound treatment 17425.3 112.0 0.1 0.1014 1.0 1965341 CMLD1_000310 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O19 compound treatment 17154.2 -159.0 -0.14 -0.1434 -1.0 1965342 CMLD1_000311 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O20 compound treatment 17593.4 280.0 0.25 0.2532 1.0 1965343 CMLD1_000312 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O21 mock treatment 17440.0 127.0 0.11 0.1146 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O22 mock treatment 17116.9 -196.0 -0.18 -0.1771 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O23 mock treatment 17108.7 -204.0 -0.18 -0.1845 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 O24 mock treatment 16948.5 -365.0 -0.33 -0.3292 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P01 compound treatment 16171.0 -1140.0 -1.03 -1.0313 -1.0 1965344 CMLD1_000313 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P02 compound treatment 15800.2 -1510.0 -1.37 -1.3661 -1.0 1965345 CMLD1_000314 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P03 compound treatment 16378.7 -934.0 -0.84 -0.8437 -1.0 1965346 CMLD1_000315 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P04 compound treatment 15825.6 -1490.0 -1.34 -1.3432 -1.0 1965347 CMLD1_000316 COC(=O)c1ccc(cc1)C23CC3(C2)C(NP(=O)(c4ccccc4)c5ccccc5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P05 compound treatment 16694.2 -619.0 -0.56 -0.5588 -1.0 1965348 CMLD1_000317 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P06 compound treatment 17228.3 -84.8 -0.08 -0.0765 -1.0 1965349 CMLD1_000318 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P07 compound treatment 17322.0 8.94 0.01 0.0081 1.0 1965350 CMLD1_000319 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P08 compound treatment 17583.0 270.0 0.24 0.2438 1.0 1965351 CMLD1_000320 COC(=O)C1(Cc2ccccc2)NCC3=C(C)C(=O)C(C)C3=C1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P09 compound treatment 17203.5 -110.0 -0.1 -0.0989 -1.0 1965352 CMLD1_000321 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P10 compound treatment 17322.9 9.84 0.01 0.0089 1.0 1965353 CMLD1_000322 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P11 compound treatment 16610.9 -702.0 -0.63 -0.6341 -1.0 1965354 CMLD1_000323 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P12 compound treatment 16011.0 -1300.0 -1.18 -1.1758 -1.0 1965355 CMLD1_000324 CC[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OC)OC[C@]4(C)[C@H]3C2=C1CN4C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P13 compound treatment 17083.0 -230.0 -0.21 -0.2077 -1.0 1965356 CMLD1_000325 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P14 compound treatment 16516.5 -797.0 -0.72 -0.7193 -1.0 1965357 CMLD1_000326 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(OC)cc5)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P15 compound treatment 16843.4 -470.0 -0.42 -0.4241 -1.0 1965358 CMLD1_000327 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P16 compound treatment 16572.1 -741.0 -0.67 -0.6691 -1.0 1965359 CMLD1_000328 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)cc7COCOc67 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P17 compound treatment 13144.3 -4170.0 -3.76 -3.7644 -1.0 1965360 CMLD1_000329 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P18 compound treatment 17465.4 152.0 0.14 0.1376 1.0 1965361 CMLD1_000330 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P19 compound treatment 17345.6 32.5 0.03 0.0294 1.0 1965362 CMLD1_000331 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P20 compound treatment 16654.3 -659.0 -0.59 -0.5949 -1.0 1965363 CMLD1_000332 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P21 mock treatment 17100.9 -212.0 -0.19 -0.1916 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P22 mock treatment 16642.2 -671.0 -0.61 -0.6058 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P23 mock treatment 16185.2 -1130.0 -1.02 -1.0185 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1462 P24 mock treatment 15066.8 -2250.0 -2.03 -2.0284 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A01 compound treatment 17466.1 224.0 0.2 0.202 1.0 2065621 ICCB6_000001 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A02 compound treatment 17041.2 -201.0 -0.18 -0.1817 -1.0 2065622 ICCB6_000002 OCCCCCCCCCc1ccc(C=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A03 compound treatment 17239.4 -3.05 0.0 -0.0028 -1.0 2065623 ICCB6_000003 CC1(C)OC(=O)C=C(CC(O)c2ccccc2)O1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A04 compound treatment 17883.2 641.0 0.58 0.5786 1.0 2065624 ICCB6_000004 CO[C@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc3ccccc3)[C@@H]1OCCCc4ccc(C=O)o4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A05 compound treatment 17539.6 297.0 0.27 0.2683 1.0 2065625 ICCB6_000005 Clc1ccccc1C(CC(=O)c2ccccc2)C(=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A06 compound treatment 16998.5 -244.0 -0.22 -0.2203 -1.0 2065626 ICCB6_000006 OCCCCCCCCCCc1ccc(C=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A07 compound treatment 16777.5 -465.0 -0.42 -0.4199 -1.0 2065627 ICCB6_000007 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A08 compound treatment 17732.5 490.0 0.44 0.4425 1.0 2065628 ICCB6_000008 OC[C@H](COCCCc1ccc(C=O)o1)OCc2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A09 compound treatment 17562.6 320.0 0.29 0.2891 1.0 2065629 ICCB6_000009 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A10 compound treatment 17563.6 321.0 0.29 0.29 1.0 2065630 ICCB6_000010 OCCOCCCc1ccc(C=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A11 compound treatment 17621.0 379.0 0.34 0.3418 1.0 2065631 ICCB6_000011 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A12 compound treatment 17643.4 401.0 0.36 0.3621 1.0 2065632 ICCB6_000012 OCc1ccc(CCc2ccc(C=O)o2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A13 compound treatment 16546.9 -696.0 -0.63 -0.6281 -1.0 2065633 ICCB6_000013 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A14 compound treatment 17120.0 -122.0 -0.11 -0.1106 -1.0 2065634 ICCB6_000014 OCCOCCOCCCc1ccc(C=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A15 compound treatment 17574.5 332.0 0.3 0.2998 1.0 ICCB6_000015 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A16 compound treatment 17521.3 279.0 0.25 0.2518 1.0 2065635 ICCB6_000016 OCC1CC2CCN1CC2CCc3ccc(C=O)o3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A17 compound treatment 17772.4 530.0 0.48 0.4785 1.0 1952805 ICCB6_000017 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A18 compound treatment 17526.8 284.0 0.26 0.2568 1.0 2065636 ICCB6_000018 OCCCCNC(=O)OCCCc1ccc(C=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A19 compound treatment 18441.7 1200.0 1.08 1.0829 1.0 1952839 ICCB6_000019 Oc1ccccc1C#CC#Cc2ccccc2O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A20 compound treatment 18510.7 1270.0 1.15 1.1452 1.0 2065637 ICCB6_000020 OCCCCc1ccc(C=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A21 compound treatment 17369.4 127.0 0.11 0.1146 1.0 1952635 ICCB6_000021 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A22 compound treatment 17191.5 -51.0 -0.05 -0.046 -1.0 2065638 ICCB6_000022 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A23 mock treatment 17322.2 79.7 0.07 0.072 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 A24 mock treatment 16614.5 -628.0 -0.57 -0.567 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B01 compound treatment 17166.8 -75.7 -0.07 -0.0683 -1.0 2065621 ICCB6_000023 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B02 compound treatment 19501.0 2260.0 2.04 2.0395 1.0 2065639 ICCB6_000024 OB1OC(COCc2ccccc2)CC=C1C(=C)CCCc3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B03 compound treatment 18280.8 1040.0 0.94 0.9376 1.0 2065640 ICCB6_000025 CC1(C)OC(=O)C=C(CC(O)C2CCCCC2)O1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B04 compound treatment 19112.7 1870.0 1.69 1.6888 1.0 2065641 ICCB6_000026 CC(C)C(=C)C1=CCC(COCc2ccccc2)OB1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B05 compound treatment 18393.1 1150.0 1.04 1.039 1.0 2065642 ICCB6_000027 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B06 compound treatment 18449.6 1210.0 1.09 1.0901 1.0 2065643 ICCB6_000028 CCCC(=C)C1=CCC(COCc2ccccc2)OB1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B07 compound treatment 17846.8 604.0 0.55 0.5457 1.0 2065644 ICCB6_000029 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B08 compound treatment 17826.4 584.0 0.53 0.5273 1.0 2065645 ICCB6_000030 O[C@@H]([C@H](Oc1ccccc1)C=C)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B09 compound treatment 17937.8 695.0 0.63 0.6279 1.0 2065646 ICCB6_000031 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B10 compound treatment 18625.8 1380.0 1.25 1.2492 1.0 2065647 ICCB6_000032 O[C@H](COCc1ccccc1)[C@H](Oc2ccccc2)C=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B11 compound treatment 17355.5 113.0 0.1 0.1021 1.0 2065648 ICCB6_000033 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B12 compound treatment 17820.9 578.0 0.52 0.5223 1.0 2065649 ICCB6_000034 CC(C)C(=C)C(=O)CCC(COCc1ccccc1)OC(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B13 compound treatment 17884.6 642.0 0.58 0.5799 1.0 2065650 ICCB6_000035 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B14 compound treatment 17210.9 -31.6 -0.03 -0.0285 -1.0 2065651 ICCB6_000036 CCCC(=C=CC[C@@H](OC(=O)Nc1ccc(Br)cc1)c2ccccc2)CCOC(=O)Nc3ccc(Br)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B15 compound treatment 17859.9 617.0 0.56 0.5576 1.0 1952458 ICCB6_000037 Fc1ccc(cc1Br)[C@@H]2C3=C(C[C@@H]4C2=CCn5n4c(=O)n(c6ccccc6)c5=O)C(=O)OC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B16 compound treatment 17956.5 714.0 0.64 0.6448 1.0 2065652 ICCB6_000038 CC(C)C(=C=CC[C@H](COCc1ccccc1)OC(=O)c2ccc(Br)cc2)CCOC(=O)c3ccc(Br)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B17 compound treatment 18632.8 1390.0 1.26 1.2555 1.0 1952808 ICCB6_000039 CCCCCc1cc2ccccc2o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B18 compound treatment 17932.7 690.0 0.62 0.6233 1.0 2065653 ICCB6_000040 CC1(C)OC[C@@H](C=C)[C@H](CCc2ccccc2)O1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B19 compound treatment 18247.9 1010.0 0.91 0.9079 1.0 1952842 ICCB6_000041 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B20 compound treatment 17184.1 -58.4 -0.05 -0.0527 -1.0 2065654 ICCB6_000042 CCC[C@@]1(CCO[Si](c2ccccc2)(c3ccccc3)C(C)(C)C)O[C@@H](Cc4ccccc4)CC=C1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B21 compound treatment 17195.7 -46.8 -0.04 -0.0422 -1.0 1952636 ICCB6_000043 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B22 compound treatment 18089.9 847.0 0.77 0.7653 1.0 3056822 ICCB6_000044 CC(C)[Si](OC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)c4ccccc4C3=O)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B23 mock treatment 17291.9 49.4 0.04 0.0447 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 B24 mock treatment 16995.8 -247.0 -0.22 -0.2227 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C01 compound treatment 16630.1 -612.0 -0.55 -0.553 -1.0 2065655 ICCB6_000045 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(C)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C02 compound treatment 19351.5 2110.0 1.9 1.9045 1.0 2065656 ICCB6_000046 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C03 compound treatment 17955.9 713.0 0.64 0.6442 1.0 2065657 ICCB6_000047 COC(=O)c1cn2c(c1C(=O)OC)c(=O)n(C)c3ccccc32 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C04 compound treatment 18971.5 1730.0 1.56 1.5613 1.0 2065658 ICCB6_000048 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@H](COC2=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C05 compound treatment 18814.1 1570.0 1.42 1.4192 1.0 2065659 ICCB6_000049 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3Cl)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C06 compound treatment 18471.6 1230.0 1.11 1.1099 1.0 2065660 ICCB6_000050 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C07 compound treatment 17368.2 126.0 0.11 0.1136 1.0 2065661 ICCB6_000051 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)CCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C08 compound treatment 17289.6 47.1 0.04 0.0426 1.0 2065662 ICCB6_000052 CC(C)[C@@H]1N(C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2)C(=O)OC1(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C09 compound treatment 18158.9 916.0 0.83 0.8276 1.0 2065663 ICCB6_000053 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C10 compound treatment 17748.4 506.0 0.46 0.4569 1.0 2065664 ICCB6_000054 COC(=O)[C@H](Cc1ccccc1)NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C11 compound treatment 17516.9 274.0 0.25 0.2478 1.0 2065665 ICCB6_000055 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C12 compound treatment 17523.1 281.0 0.25 0.2534 1.0 2065666 ICCB6_000056 CCc1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C13 compound treatment 17644.3 402.0 0.36 0.3629 1.0 1065064 ICCB6_000057 [O-][N+](=O)c1ccc(CBr)c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C14 compound treatment 17206.8 -35.7 -0.03 -0.0322 -1.0 2065667 ICCB6_000058 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(Oc3ccccc3)cc2)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C15 compound treatment 17601.8 359.0 0.32 0.3245 1.0 1952482 ICCB6_000059 Fc1ccc(cc1Br)[C@H]2C3=CC[C@H]4[C@@H]([C@@H]3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C16 compound treatment 17893.7 651.0 0.59 0.5881 1.0 2065668 ICCB6_000060 COc1cccc(C)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C17 compound treatment 18311.2 1070.0 0.97 0.9651 1.0 1952809 ICCB6_000061 CC(=O)Oc1ccccc1C#Cc2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C18 compound treatment 17719.7 477.0 0.43 0.431 1.0 2065669 ICCB6_000062 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(C#N)cc2)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C19 compound treatment 18103.0 861.0 0.78 0.7771 1.0 1952773 ICCB6_000063 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C20 compound treatment 17721.2 479.0 0.43 0.4323 1.0 2065670 ICCB6_000064 CCOC(=O)CNC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C21 compound treatment 17325.1 82.6 0.07 0.0746 1.0 1952585 ICCB6_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C22 compound treatment 17986.1 744.0 0.67 0.6715 1.0 2065671 ICCB6_000066 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2F)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C23 mock treatment 17881.3 639.0 0.58 0.5769 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 C24 mock treatment 17407.2 165.0 0.15 0.1488 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D01 compound treatment 17693.0 451.0 0.41 0.4068 1.0 2065672 ICCB6_000067 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D02 compound treatment 18647.9 1410.0 1.27 1.2691 1.0 2065673 ICCB6_000068 CC(C)[Si](OC[C@@H]1CC=C(C)B(O)O1)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D03 compound treatment 17768.2 526.0 0.47 0.4748 1.0 2065674 ICCB6_000069 CCOC(=O)C1[C@H](CCc2ccccc2)O[C@H](CCc3ccccc3)CC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D04 compound treatment 18543.7 1300.0 1.18 1.175 1.0 2065675 ICCB6_000070 CC(C)[Si](OC[C@H]1OB(O)CC=C1)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D05 compound treatment 19018.0 1780.0 1.6 1.6033 1.0 2065676 ICCB6_000071 C[Si](C)(C(N[Si](=O)(=O)c1ccccc1)c2ccccc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D06 compound treatment 19064.6 1820.0 1.65 1.6454 1.0 2065677 ICCB6_000072 CC(C)[Si](OCC(O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D07 compound treatment 17590.7 348.0 0.31 0.3145 1.0 2065678 ICCB6_000073 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D08 compound treatment 18315.6 1070.0 0.97 0.9691 1.0 2065679 ICCB6_000074 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D09 compound treatment 18030.2 788.0 0.71 0.7113 1.0 2065680 ICCB6_000075 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)CCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D10 compound treatment 17721.6 479.0 0.43 0.4327 1.0 2065681 ICCB6_000076 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D11 compound treatment 17625.7 383.0 0.35 0.3461 1.0 2065682 ICCB6_000077 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D12 compound treatment 18162.3 920.0 0.83 0.8306 1.0 2065683 ICCB6_000078 CC(C)[Si](OCC(O)/C(=C\CO)/C)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D13 compound treatment 17337.5 95.0 0.09 0.0858 1.0 1952278 ICCB6_000079 COC(=O)c1nc(oc1C)C(NC(=O)CCc2cn(CC=C)c3ccccc23)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D14 compound treatment 17373.1 131.0 0.12 0.118 1.0 2065684 ICCB6_000080 CC(C)[Si](OCC(O)/C=C\CO)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D15 compound treatment 18211.7 969.0 0.88 0.8752 1.0 2065685 ICCB6_000081 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D16 compound treatment 17525.7 283.0 0.26 0.2558 1.0 2065686 ICCB6_000082 CC(C)[Si](OC[C@@H](O)[C@@]1(C)OC(C)(C)OC1CO)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D17 compound treatment 18385.6 1140.0 1.03 1.0323 1.0 1952811 ICCB6_000083 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D18 compound treatment 18027.6 785.0 0.71 0.709 1.0 2065687 ICCB6_000084 CC(C)[Si](OC[C@@H](O)[C@H]1OC(C)(C)OC1CO)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D19 compound treatment 18816.1 1570.0 1.42 1.421 1.0 1952780 ICCB6_000085 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D20 compound treatment 18175.4 933.0 0.84 0.8425 1.0 2065688 ICCB6_000086 CC1(C)OC(CO)[C@H](O1)[C@H](O)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D21 compound treatment 18779.1 1540.0 1.39 1.3876 1.0 1952670 ICCB6_000087 COCCNC(=O)OC[C@H]1CCC[C@@]2(C[C@@H](C[C@@H](CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D22 compound treatment 17787.8 545.0 0.49 0.4925 1.0 2065689 ICCB6_000088 C/C(=C/CO)/[C@H](O)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D23 mock treatment 17567.4 325.0 0.29 0.2934 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 D24 mock treatment 17423.2 181.0 0.16 0.1632 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E01 compound treatment 18280.2 1040.0 0.94 0.9371 1.0 2065690 ICCB6_000089 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)c(Cl)c4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E02 compound treatment 18249.1 1010.0 0.91 0.909 1.0 2065691 ICCB6_000090 COc1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E03 compound treatment 17326.9 84.4 0.08 0.0763 1.0 2065692 ICCB6_000091 CCOC(=O)C1[C@@H](O[C@@H](CC1=O)c2ccccc2)C3CCCCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E04 compound treatment 18527.5 1290.0 1.16 1.1604 1.0 2065693 ICCB6_000092 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](O)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E05 compound treatment 16078.8 -1160.0 -1.05 -1.0508 -1.0 2065694 ICCB6_000093 COc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)[Si](C)(C)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E06 compound treatment 18349.4 1110.0 1.0 0.9996 1.0 2065695 ICCB6_000094 CC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E07 compound treatment 17494.2 252.0 0.23 0.2273 1.0 2065696 ICCB6_000095 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E08 compound treatment 16995.6 -247.0 -0.22 -0.2229 -1.0 2065697 ICCB6_000096 CCOC(=O)c1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E09 compound treatment 17686.4 444.0 0.4 0.4009 1.0 2065698 ICCB6_000097 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E10 compound treatment 18605.3 1360.0 1.23 1.2307 1.0 2065699 ICCB6_000098 CCCCOC(=O)c1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E11 compound treatment 18502.7 1260.0 1.14 1.138 1.0 1952474 ICCB6_000099 OCCCCCNC(CCO)Cc1ccc2ccccc2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E12 compound treatment 17458.2 216.0 0.19 0.1948 1.0 2065700 ICCB6_000100 COC(=O)[C@@H](NC(=O)OC/C=C/c1ccc(CCCCCCO)o1)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E13 compound treatment 17334.1 91.6 0.08 0.0828 1.0 1952280 ICCB6_000101 COC(=O)c1nc2oc1CC/C=C/Cn3cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C)c4ccccc34 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E14 compound treatment 17591.6 349.0 0.32 0.3153 1.0 2065701 ICCB6_000102 COc1cccc(Cl)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E15 compound treatment 16007.1 -1240.0 -1.12 -1.1155 -1.0 1952487 ICCB6_000103 Fc1ccc(cc1Br)[C@H]2C3=CCn4n(C3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)c(=O)n(c6ccccc6)c4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E16 compound treatment 17488.6 246.0 0.22 0.2223 1.0 2065702 ICCB6_000104 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E17 compound treatment 17987.4 745.0 0.67 0.6727 1.0 1952813 ICCB6_000105 OCCCC#Cc1cc(O)cc(Cl)c1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E18 compound treatment 19049.5 1810.0 1.63 1.6318 1.0 2065703 ICCB6_000106 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](OC(=O)C)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E19 compound treatment 18637.5 1400.0 1.26 1.2597 1.0 3107406 ICCB6_000107 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E20 compound treatment 18215.1 973.0 0.88 0.8783 1.0 2065704 ICCB6_000108 C[C@@H]([C@H](OC(=O)C)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E21 compound treatment 18315.8 1070.0 0.97 0.9692 1.0 ICCB6_000109 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E22 compound treatment 18263.8 1020.0 0.92 0.9223 1.0 2065705 ICCB6_000110 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2cccc(C)c2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E23 mock treatment 17724.6 482.0 0.44 0.4354 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 E24 mock treatment 16679.8 -563.0 -0.51 -0.5081 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F01 compound treatment 17749.0 507.0 0.46 0.4574 1.0 2065706 ICCB6_000111 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(OC)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F02 compound treatment 19060.2 1820.0 1.64 1.6414 1.0 2065707 ICCB6_000112 CC(C)[Si](OC[C@@H](O)C(C=C)C(O)c1ccccc1)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F03 compound treatment 18353.5 1110.0 1.0 1.0033 1.0 1009686 ICCB6_000113 O=C(CC(C(=O)c1ccccc1)c2ccccc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F04 compound treatment 19166.4 1920.0 1.74 1.7373 1.0 2065708 ICCB6_000114 OC/C=C\C(O)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F05 compound treatment 17946.5 704.0 0.64 0.6358 1.0 2065709 ICCB6_000115 CCCCCCCCNC(=O)CC[C@H]1O[C@H](O[C@H]2O[C@H](CCC(=O)NCCCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F06 compound treatment 16794.4 -448.0 -0.4 -0.4046 -1.0 2065710 ICCB6_000116 CC1=C([C@H](O)C(C)(C)C)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F07 compound treatment 17117.7 -125.0 -0.11 -0.1127 -1.0 2065711 ICCB6_000117 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F08 compound treatment 17925.2 683.0 0.62 0.6165 1.0 2065712 ICCB6_000118 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F09 compound treatment 17526.2 284.0 0.26 0.2562 1.0 2065713 ICCB6_000119 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F10 compound treatment 18177.0 935.0 0.84 0.8439 1.0 2065714 ICCB6_000120 C[C@@H](O)C1=CC[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F11 compound treatment 17854.3 612.0 0.55 0.5525 1.0 1952476 ICCB6_000121 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2c(Br)sc3ccc(Cl)cc23)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F12 compound treatment 18140.3 898.0 0.81 0.8108 1.0 2065715 ICCB6_000122 OC[C@@H]1[C@H]2[C@@H](CC=C1CO)C(=O)N(Cc3ccccc3)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F13 compound treatment 17311.2 68.7 0.06 0.0621 1.0 1952282 ICCB6_000123 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F14 compound treatment 17345.4 103.0 0.09 0.093 1.0 2065716 ICCB6_000124 CC1=C(CO)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F15 compound treatment 18380.4 1140.0 1.03 1.0276 1.0 1952488 ICCB6_000125 Fc1ccc(cc1Br)[C@H]2C3=CCC4=C(C3CC5=C2C(=O)C(=CC5=O)I)C(=O)C(=CC4=O)I 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F16 compound treatment 17982.1 740.0 0.67 0.6679 1.0 2065717 ICCB6_000126 C/C(=C/CO)/C(O)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F17 compound treatment 18406.0 1160.0 1.05 1.0507 1.0 1952814 ICCB6_000127 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F18 compound treatment 17079.6 -163.0 -0.15 -0.1471 -1.0 2065718 ICCB6_000128 CC(C)[Si](OCC1OB(O)CC=C1C)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F19 compound treatment 18861.5 1620.0 1.46 1.462 1.0 1952785 ICCB6_000129 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F20 compound treatment 17596.0 354.0 0.32 0.3193 1.0 2065719 ICCB6_000130 OB1CC=C(C(O1)c2ccccc2)C(=C)COCc3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F21 compound treatment 19214.5 1970.0 1.78 1.7808 1.0 3107360 ICCB6_000131 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F22 compound treatment 16432.5 -810.0 -0.73 -0.7314 -1.0 2065720 ICCB6_000132 OC/C=C(\C(O)c1ccccc1)/C(=C)COCc2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F23 mock treatment 17125.0 -117.0 -0.11 -0.1061 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 F24 mock treatment 16842.9 -400.0 -0.36 -0.3608 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G01 compound treatment 17833.1 591.0 0.53 0.5334 1.0 2065721 ICCB6_000133 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4cccs4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G02 compound treatment 18257.8 1020.0 0.92 0.9169 1.0 3057351 ICCB6_000134 CC(C)C[C@H](CI)C(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G03 compound treatment 18803.0 1560.0 1.41 1.4092 1.0 2065722 ICCB6_000135 Clc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)C(=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G04 compound treatment 18614.3 1370.0 1.24 1.2388 1.0 3057353 ICCB6_000136 CC(C)(C)OC[C@@H](O)[C@H]1O[C@H](NO)C2OC(C)(C)OC12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G05 compound treatment 18638.4 1400.0 1.26 1.2606 1.0 2065723 ICCB6_000137 CCCCCCCNCC(=O)NC[C@H]1O[C@H](O[C@H]2O[C@H](CNC(=O)CCNCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G06 compound treatment 18639.5 1400.0 1.26 1.2615 1.0 2065724 ICCB6_000138 CC(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G07 compound treatment 17262.4 19.9 0.02 0.018 1.0 2065725 ICCB6_000139 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G08 compound treatment 18082.4 840.0 0.76 0.7585 1.0 2065726 ICCB6_000140 CC(C)(C)[Si](C)(C)OCC1=CC(C#C)N(C=C1)C(=O)c2ccccc2Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G09 compound treatment 17053.9 -189.0 -0.17 -0.1703 -1.0 2065727 ICCB6_000141 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G10 compound treatment 17913.0 671.0 0.61 0.6055 1.0 3057357 ICCB6_000142 OC(=O)c1[se]c2ccccc2c1Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G11 compound treatment 17514.4 272.0 0.25 0.2456 1.0 1952478 ICCB6_000143 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2ccc3ccccc3c2Br)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G12 compound treatment 17566.3 324.0 0.29 0.2924 1.0 3057359 ICCB6_000144 CC(C)(C)[Si](C)(C)OCC1=CC(C=C)N(C=C1)C(=O)c2[se]c3ccccc3c2Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G13 compound treatment 17136.5 -106.0 -0.1 -0.0957 -1.0 1952284 ICCB6_000145 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]2C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G14 compound treatment 17822.9 580.0 0.52 0.5241 1.0 2065728 ICCB6_000146 CCCCCC1C=C(CO[Si](C)(C)C(C)(C)C)C=CN1C(=O)c2ccccc2Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G15 compound treatment 17035.6 -207.0 -0.19 -0.1868 -1.0 2065729 ICCB6_000147 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G16 compound treatment 17525.3 283.0 0.26 0.2554 1.0 2065730 ICCB6_000148 CC(C)(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G17 compound treatment 17437.4 195.0 0.18 0.176 1.0 1952760 ICCB6_000149 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G18 compound treatment 17881.9 639.0 0.58 0.5774 1.0 2065731 ICCB6_000150 CC(=O)N[C@@H](CI)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G19 compound treatment 18330.1 1090.0 0.98 0.9822 1.0 1952788 ICCB6_000151 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G20 compound treatment 18308.1 1070.0 0.96 0.9623 1.0 2065732 ICCB6_000152 COc1cc2CCN(Cc3ccccc3Br)C(C=C)c2cc1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G21 compound treatment 17947.0 705.0 0.64 0.6362 1.0 1952728 ICCB6_000153 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G22 compound treatment 18023.4 781.0 0.71 0.7052 1.0 2065733 ICCB6_000154 CN1C(=O)C2C(C1=O)C3(C4C(C5C=C(CCCO[Si](C)(C)C(C)(C)C)CC2N53)C(=O)N(C)C4=O)C(=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G23 mock treatment 17796.0 554.0 0.5 0.4999 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 G24 mock treatment 17473.9 231.0 0.21 0.209 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H01 compound treatment 17149.6 -92.9 -0.08 -0.0838 -1.0 2065734 ICCB6_000155 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4Cl)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H02 compound treatment 18718.6 1480.0 1.33 1.333 1.0 2065735 ICCB6_000156 CC(=C)C1=CCB(O)OC1c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H03 compound treatment 18459.2 1220.0 1.1 1.0987 1.0 2065736 ICCB6_000157 CC(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H04 compound treatment 18617.2 1370.0 1.24 1.2414 1.0 2065737 ICCB6_000158 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H05 compound treatment 18899.5 1660.0 1.5 1.4963 1.0 2065738 ICCB6_000159 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H06 compound treatment 16969.7 -273.0 -0.25 -0.2463 -1.0 2065739 ICCB6_000160 CC(=C)/C(=C/CO)/C(O)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H07 compound treatment 17584.0 342.0 0.31 0.3084 1.0 2065740 ICCB6_000161 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccc(OC)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H08 compound treatment 18206.1 964.0 0.87 0.8702 1.0 2065741 ICCB6_000162 CC1=NC(C)(C)[C@@H]2CCC(=C)C1C2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H09 compound treatment 16252.4 -990.0 -0.89 -0.894 -1.0 2065742 ICCB6_000163 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H10 compound treatment 17919.0 677.0 0.61 0.6109 1.0 2065743 ICCB6_000164 C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H11 compound treatment 18138.4 896.0 0.81 0.809 1.0 1952534 ICCB6_000165 C[C@H](N)C(Oc1ccccc1Br)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H12 compound treatment 18221.2 979.0 0.88 0.8838 1.0 2065744 ICCB6_000166 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H13 compound treatment 16311.8 -931.0 -0.84 -0.8404 -1.0 1952286 ICCB6_000167 COC(=O)c1nc(oc1CCC=C)C(NC(=O)[C@H](Cc2cn(CC=C)cn2)NC(=O)OCc3ccccc3)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H14 compound treatment 17579.2 337.0 0.3 0.3041 1.0 2065745 ICCB6_000168 CC(C)C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H15 compound treatment 17180.3 -62.2 -0.06 -0.0561 -1.0 1952677 ICCB6_000169 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H16 compound treatment 17527.5 285.0 0.26 0.2574 1.0 2065746 ICCB6_000170 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H17 compound treatment 17904.0 662.0 0.6 0.5974 1.0 1952821 ICCB6_000171 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H18 compound treatment 17864.8 622.0 0.56 0.562 1.0 2065747 ICCB6_000172 COc1cc(C[C@H]2NC(C)(C)C3CCC(=C)[C@H]2C3)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H19 compound treatment 18588.8 1350.0 1.22 1.2158 1.0 1952600 ICCB6_000173 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H20 compound treatment 17855.9 613.0 0.55 0.5539 1.0 2065748 ICCB6_000174 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2C)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H21 compound treatment 17044.1 -198.0 -0.18 -0.1791 -1.0 1952730 ICCB6_000175 O=c1cc(Cc2ccccc2)c3ccccc3o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H22 compound treatment 17059.5 -183.0 -0.17 -0.1652 -1.0 2065749 ICCB6_000176 CC1(C)N=C(/C=C/2\C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H23 mock treatment 18398.0 1160.0 1.04 1.0435 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 H24 mock treatment 17020.8 -222.0 -0.2 -0.2002 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I01 compound treatment 17225.2 -17.3 -0.02 -0.0156 -1.0 2065750 ICCB6_000177 COC(=O)[C@@H]1[C@H](N([C@H](c2ccccc2)[C@@]13C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6)C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I02 compound treatment 17701.7 459.0 0.41 0.4147 1.0 2065751 ICCB6_000178 CC(C)(C)[Si](C)(C)OCCCC1=CC2C3C(C(=O)N(Cc4ccccc4)C3=O)C5(C6C(C(C1)N25)C(=O)N(Cc7ccccc7)C6=O)C(=O)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I03 compound treatment 17843.7 601.0 0.54 0.5429 1.0 2065752 ICCB6_000179 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Cl)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I04 compound treatment 18319.4 1080.0 0.97 0.9725 1.0 2065753 ICCB6_000180 COc1cc(CN[C@@H](C)[C@H](Oc2ccccc2Br)c3ccccc3)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I05 compound treatment 18673.2 1430.0 1.29 1.292 1.0 2065754 ICCB6_000181 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I06 compound treatment 18419.6 1180.0 1.06 1.063 1.0 2065755 ICCB6_000182 COc1cc(CN[C@H]([C@H](O)c2ccccc2)c3ccccc3)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I07 compound treatment 15816.1 -1430.0 -1.29 -1.288 -1.0 2065756 ICCB6_000183 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I08 compound treatment 16969.8 -273.0 -0.25 -0.2462 -1.0 2065757 ICCB6_000184 COc1cc(CN(Cc2ccccc2Br)[C@H]([C@H](O)c3ccccc3)c4ccccc4)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I09 compound treatment 17456.6 214.0 0.19 0.1934 1.0 2065758 ICCB6_000185 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I10 compound treatment 17378.5 136.0 0.12 0.1229 1.0 2065759 ICCB6_000186 COc1cc(CN(Cc2ccccc2Br)[C@H](C)C(Oc3ccccc3Br)c4ccccc4)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I11 compound treatment 17300.1 57.6 0.05 0.0521 1.0 1952544 ICCB6_000187 O=C1Nc2ccccc2[C@@]31[C@@H](C#N)C4N([C@H]3c5ccccc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I12 compound treatment 17996.4 754.0 0.68 0.6808 1.0 2065760 ICCB6_000188 COc1cc(CN(Cc2ccccc2Br)[C@H](C(Oc3ccccc3Br)c4ccccc4)c5ccccc5)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I13 compound treatment 17418.6 176.0 0.16 0.1591 1.0 1952288 ICCB6_000189 COC(=O)c1nc2oc1CC/C=C/Cn3cnc(C[C@H](NC(=O)OCc4ccccc4)C(=O)NC2C(C)C)c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I14 compound treatment 17804.2 562.0 0.51 0.5073 1.0 2065761 ICCB6_000190 C[C@@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I15 compound treatment 17484.1 242.0 0.22 0.2182 1.0 1952679 ICCB6_000191 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I16 compound treatment 17009.0 -233.0 -0.21 -0.2108 -1.0 2065762 ICCB6_000192 C[C@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I17 compound treatment 17672.8 430.0 0.39 0.3886 1.0 1952823 ICCB6_000193 C#Cc1ccccc1Oc2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I18 compound treatment 17994.2 752.0 0.68 0.6788 1.0 2065763 ICCB6_000194 C[C@H](C(Oc1ccc(cc1)[N+](=O)[O-])c2ccccc2)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I19 compound treatment 17631.4 389.0 0.35 0.3512 1.0 1952601 ICCB6_000195 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I20 compound treatment 18418.1 1180.0 1.06 1.0616 1.0 2065764 ICCB6_000196 C[C@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I21 compound treatment 17785.0 543.0 0.49 0.4899 1.0 1952746 ICCB6_000197 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I22 compound treatment 18112.2 870.0 0.79 0.7854 1.0 2065765 ICCB6_000198 C[C@@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I23 mock treatment 17566.1 324.0 0.29 0.2923 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 I24 mock treatment 16881.5 -361.0 -0.33 -0.3259 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J01 compound treatment 16603.3 -639.0 -0.58 -0.5772 -1.0 2065766 ICCB6_000199 COC(=O)C1=CN([C@H](c2ccccc2)[C@]31C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J02 compound treatment 18791.6 1550.0 1.4 1.3989 1.0 2065767 ICCB6_000200 CC1(C)N[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J03 compound treatment 18724.6 1480.0 1.34 1.3384 1.0 2065768 ICCB6_000201 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Br)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J04 compound treatment 19205.9 1960.0 1.77 1.773 1.0 2065769 ICCB6_000202 CN1[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J05 compound treatment 17916.8 674.0 0.61 0.6089 1.0 2065770 ICCB6_000203 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J06 compound treatment 18110.9 868.0 0.78 0.7842 1.0 2065771 ICCB6_000204 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J07 compound treatment 17350.9 108.0 0.1 0.0979 1.0 2065772 ICCB6_000205 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J08 compound treatment 18436.4 1190.0 1.08 1.0781 1.0 2065773 ICCB6_000206 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J09 compound treatment 17483.4 241.0 0.22 0.2176 1.0 2065774 ICCB6_000207 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J10 compound treatment 17947.5 705.0 0.64 0.6367 1.0 2065775 ICCB6_000208 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J11 compound treatment 18081.4 839.0 0.76 0.7576 1.0 2065776 ICCB6_000209 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J12 compound treatment 17860.8 618.0 0.56 0.5584 1.0 2065777 ICCB6_000210 OCCOc1cccc(c1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J13 compound treatment 17124.8 -118.0 -0.11 -0.1062 -1.0 1952295 ICCB6_000211 COC(=O)c1nc(oc1CC(=O)CCl)C(NC(=O)NC(=O)OC(C)(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J14 compound treatment 17676.5 434.0 0.39 0.3919 1.0 2065778 ICCB6_000212 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J15 compound treatment 17328.9 86.4 0.08 0.0781 1.0 1952690 ICCB6_000213 COC(=O)CC(C(=O)OC)c1ccccc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J16 compound treatment 17572.6 330.0 0.3 0.2981 1.0 2065779 ICCB6_000214 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC(C(=O)OC)C(=O)OC)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J17 compound treatment 17492.4 250.0 0.23 0.2257 1.0 1952825 ICCB6_000215 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J18 compound treatment 18076.8 834.0 0.75 0.7534 1.0 2065780 ICCB6_000216 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J19 compound treatment 18135.9 893.0 0.81 0.8068 1.0 1952605 ICCB6_000217 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J20 compound treatment 18143.0 901.0 0.81 0.8132 1.0 2065781 ICCB6_000218 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J21 compound treatment 17988.7 746.0 0.67 0.6739 1.0 3005760 ICCB6_000219 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J22 compound treatment 17456.5 214.0 0.19 0.1933 1.0 2065782 ICCB6_000220 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCNC(=O)N)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J23 mock treatment 17124.4 -118.0 -0.11 -0.1066 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 J24 mock treatment 17588.4 346.0 0.31 0.3124 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K01 compound treatment 17618.8 376.0 0.34 0.3398 1.0 2065783 ICCB6_000221 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C)c5ccccc52 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K02 compound treatment 18532.3 1290.0 1.16 1.1647 1.0 2065784 ICCB6_000222 CC(Oc1ccccc1Br)[C@H](N(C)C)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K03 compound treatment 18260.2 1020.0 0.92 0.919 1.0 2065785 ICCB6_000223 COC(=O)C(C(c1ccc(OC)cc1)[Si](C)(C)c2ccccc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K04 compound treatment 17962.9 720.0 0.65 0.6506 1.0 2065786 ICCB6_000224 C[C@H](C(Oc1ccccc1[N+](=O)[O-])c2ccccc2)N(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K05 compound treatment 16805.4 -437.0 -0.39 -0.3947 -1.0 2065787 ICCB6_000225 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K06 compound treatment 18302.2 1060.0 0.96 0.957 1.0 2065788 ICCB6_000226 COc1cc(/C=C/C=O)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K07 compound treatment 17244.3 1.85 0.0 0.0017 1.0 2065789 ICCB6_000227 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)CCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K08 compound treatment 17735.8 493.0 0.45 0.4455 1.0 2065790 ICCB6_000228 COc1cc(/C=C/CN[C@H](C)[C@@H](O)c2ccccc2)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K09 compound treatment 17339.6 97.1 0.09 0.0877 1.0 2065791 ICCB6_000229 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccc(OC)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K10 compound treatment 17350.5 108.0 0.1 0.0976 1.0 2065792 ICCB6_000230 CC(C)[Si](OCC1CCC=CC1)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K11 compound treatment 17343.5 101.0 0.09 0.0912 1.0 1034979 ICCB6_000231 c1c(cn2ccccc12)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K12 compound treatment 16885.1 -357.0 -0.32 -0.3227 -1.0 2065793 ICCB6_000232 CC1(C)COC(=O)C1OC(=O)C2CC3CCC2C=C3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K13 compound treatment 17245.3 2.85 0.0 0.0026 1.0 1952379 ICCB6_000233 CC(C)[Si](OCc1ccc(C=O)o1)(C(C)C)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K14 compound treatment 17160.6 -81.9 -0.07 -0.0739 -1.0 2065794 ICCB6_000234 OCC1CC2CCC1C=C2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K15 compound treatment 17250.1 7.65 0.01 0.0069 1.0 1952707 ICCB6_000235 CCCCSc1cc(=O)oc2cc(OC)ccc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K16 compound treatment 14113.8 -3130.0 -2.83 -2.8252 -1.0 2065795 ICCB6_000236 Ic1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K17 compound treatment 16811.5 -431.0 -0.39 -0.3892 -1.0 1952828 ICCB6_000237 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K18 compound treatment 18011.5 769.0 0.69 0.6945 1.0 2065796 ICCB6_000238 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3cccnc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K19 compound treatment 17992.0 750.0 0.68 0.6768 1.0 1952608 ICCB6_000239 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K20 compound treatment 16798.0 -444.0 -0.4 -0.4013 -1.0 2065797 ICCB6_000240 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3ccco3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K21 compound treatment 17802.2 560.0 0.51 0.5055 1.0 3005761 ICCB6_000241 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K22 compound treatment 17434.1 192.0 0.17 0.1731 1.0 2065798 ICCB6_000242 Ic1ccc2NC(=O)/C(=C/C#N)/c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K23 mock treatment 16879.2 -363.0 -0.33 -0.328 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 K24 mock treatment 15223.4 -2020.0 -1.82 -1.8232 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L01 compound treatment 17663.3 421.0 0.38 0.38 1.0 2065799 ICCB6_000243 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccccc52 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L02 compound treatment 18213.3 971.0 0.88 0.8767 1.0 2065800 ICCB6_000244 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#Cc6ccccc6F)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L03 compound treatment 18075.8 833.0 0.75 0.7525 1.0 2065801 ICCB6_000245 COC(=O)C(C(c1ccco1)[Si](C)(C)c2ccccc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L04 compound treatment 18216.7 974.0 0.88 0.8798 1.0 2065802 ICCB6_000246 CCCCC[C@H](O)C#Cc1ccc2NC(=O)[C@@]3([C@H](C4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N(C)OC)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L05 compound treatment 17377.2 135.0 0.12 0.1217 1.0 2065803 ICCB6_000247 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L06 compound treatment 18725.5 1480.0 1.34 1.3392 1.0 2065804 ICCB6_000248 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)[C@H](C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L07 compound treatment 17179.5 -63.0 -0.06 -0.0568 -1.0 2065805 ICCB6_000249 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L08 compound treatment 18910.6 1670.0 1.51 1.5064 1.0 2065806 ICCB6_000250 OCCOc1ccc(cc1)C2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L09 compound treatment 16636.0 -606.0 -0.55 -0.5476 -1.0 2065807 ICCB6_000251 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L10 compound treatment 17032.8 -210.0 -0.19 -0.1893 -1.0 2065808 ICCB6_000252 CON(C)C(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(I)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L11 compound treatment 16819.4 -423.0 -0.38 -0.382 -1.0 2065809 ICCB6_000253 COC(=O)Cc1cn[nH]c1C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L12 compound treatment 17502.7 260.0 0.24 0.235 1.0 2065810 ICCB6_000254 CCOC(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(Br)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L13 compound treatment 17851.3 609.0 0.55 0.5498 1.0 1952411 ICCB6_000255 CC(C)[Si](OCc1ccc(o1)[C@@H](O)[C@H](C)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3)(C(C)C)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L14 compound treatment 17590.3 348.0 0.31 0.3141 1.0 2065811 ICCB6_000256 OCCOc1ccc(cc1)C2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L15 compound treatment 17444.9 202.0 0.18 0.1828 1.0 1952793 ICCB6_000257 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L16 compound treatment 17380.4 138.0 0.12 0.1246 1.0 2065812 ICCB6_000258 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L17 compound treatment 17874.2 632.0 0.57 0.5705 1.0 1952829 ICCB6_000259 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L18 compound treatment 17599.1 357.0 0.32 0.3221 1.0 2065813 ICCB6_000260 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L19 compound treatment 17891.0 649.0 0.59 0.5856 1.0 1952582 ICCB6_000261 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOC)O3)O2)OC(=O)NCc4cccc5ccccc45 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L20 compound treatment 18144.9 902.0 0.81 0.8149 1.0 2065814 ICCB6_000262 CON(C)C(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(Br)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L21 compound treatment 18068.5 826.0 0.75 0.7459 1.0 1952748 ICCB6_000263 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L22 compound treatment 18423.6 1180.0 1.07 1.0666 1.0 2065815 ICCB6_000264 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L23 mock treatment 17589.4 347.0 0.31 0.3133 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 L24 mock treatment 17011.7 -231.0 -0.21 -0.2084 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M01 compound treatment 15200.9 -2040.0 -1.84 -1.8435 -1.0 2065816 ICCB6_000265 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccc(Cl)cc52 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M02 compound treatment 16320.8 -922.0 -0.83 -0.8323 -1.0 2065817 ICCB6_000266 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M03 compound treatment 17590.4 348.0 0.31 0.3142 1.0 2065818 ICCB6_000267 COc1ccc(cc1)C(CC(=O)c2ccccc2)[Si](C)(C)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M04 compound treatment 18423.5 1180.0 1.07 1.0665 1.0 2065819 ICCB6_000268 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M05 compound treatment 17866.2 624.0 0.56 0.5632 1.0 2065820 ICCB6_000269 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M06 compound treatment 14618.9 -2620.0 -2.37 -2.3691 -1.0 2065821 ICCB6_000270 COC(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M07 compound treatment 16936.0 -306.0 -0.28 -0.2767 -1.0 2065822 ICCB6_000271 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M08 compound treatment 17624.6 382.0 0.35 0.3451 1.0 2065823 ICCB6_000272 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCC4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M09 compound treatment 17127.9 -115.0 -0.1 -0.1034 -1.0 2065824 ICCB6_000273 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M10 compound treatment 18007.2 765.0 0.69 0.6906 1.0 2065825 ICCB6_000274 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCc4ccccc4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M11 compound treatment 17273.8 31.3 0.03 0.0283 1.0 2065826 ICCB6_000275 CC(C(=O)O)c1ccccc1C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M12 compound treatment 17763.9 521.0 0.47 0.4709 1.0 2065827 ICCB6_000276 OCCNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(I)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M13 compound treatment 17363.8 121.0 0.11 0.1096 1.0 1952416 ICCB6_000277 Clc1c(Cl)c(Cl)c(OCc2ccccc2)c(Cl)c1Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M14 compound treatment 17942.6 700.0 0.63 0.6322 1.0 2065828 ICCB6_000278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M15 compound treatment 17540.6 298.0 0.27 0.2692 1.0 1952795 ICCB6_000279 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M16 compound treatment 17640.0 398.0 0.36 0.359 1.0 2065829 ICCB6_000280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)C(C(OC3=O)c5ccccc5)c6ccccc6)C(=O)N(C)OC)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M17 compound treatment 17336.8 94.3 0.09 0.0852 1.0 1952832 ICCB6_000281 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M18 compound treatment 17155.4 -87.1 -0.08 -0.0786 -1.0 3176523 ICCB6_000282 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCC(C)C)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M19 compound treatment 16400.2 -842.0 -0.76 -0.7606 -1.0 1952627 ICCB6_000283 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M20 compound treatment 17136.1 -106.0 -0.1 -0.096 -1.0 3056713 ICCB6_000284 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@@H](C(C)C)C(=O)OC)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M21 compound treatment 17461.5 219.0 0.2 0.1978 1.0 1107217 ICCB6_000285 Cc1cccnc1I 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M22 compound treatment 17454.1 212.0 0.19 0.1911 1.0 3176524 ICCB6_000286 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@H](C)c5ccccc5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M23 mock treatment 17340.5 98.0 0.09 0.0885 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 M24 mock treatment 16722.5 -520.0 -0.47 -0.4695 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N01 compound treatment 17523.5 281.0 0.25 0.2538 1.0 2065830 ICCB6_000287 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccc(Cl)cc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N02 compound treatment 17488.0 246.0 0.22 0.2217 1.0 2065831 ICCB6_000288 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N03 compound treatment 18207.7 965.0 0.87 0.8716 1.0 2065832 ICCB6_000289 C[Si](C)(F)C(CC(=O)c1ccccc1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N04 compound treatment 17852.9 610.0 0.55 0.5512 1.0 2065833 ICCB6_000290 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N(C)OC)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N05 compound treatment 17429.9 187.0 0.17 0.1693 1.0 2065834 ICCB6_000291 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N06 compound treatment 18174.4 932.0 0.84 0.8416 1.0 2065835 ICCB6_000292 CC1(C)N[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC1CCC4=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N07 compound treatment 17645.7 403.0 0.36 0.3641 1.0 2065836 ICCB6_000293 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccc(OC)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N08 compound treatment 17547.5 305.0 0.28 0.2755 1.0 2065837 ICCB6_000294 CN1[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N09 compound treatment 18027.6 785.0 0.71 0.709 1.0 2065838 ICCB6_000295 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N10 compound treatment 17217.9 -24.6 -0.02 -0.0222 -1.0 2065839 ICCB6_000296 Cc1ccc(cc1)S(=O)(=O)N[C@H]2CC3CCC2(C)C3(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N11 compound treatment 17033.8 -209.0 -0.19 -0.1884 -1.0 2065840 ICCB6_000297 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N12 compound treatment 18090.2 848.0 0.77 0.7655 1.0 2065841 ICCB6_000298 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N13 compound treatment 17350.0 108.0 0.1 0.0971 1.0 1952445 ICCB6_000299 Clc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc(CNC(=O)OCc5ccccc5)cc4)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N14 compound treatment 17621.2 379.0 0.34 0.342 1.0 2065842 ICCB6_000300 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N15 compound treatment 17744.9 502.0 0.45 0.4537 1.0 1952801 ICCB6_000301 Oc1ccccc1C#Cc2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N16 compound treatment 17573.2 331.0 0.3 0.2987 1.0 2065843 ICCB6_000302 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N17 compound treatment 16272.5 -970.0 -0.88 -0.8759 -1.0 1952836 ICCB6_000303 CC(=O)c1ccc2oc(cc2c1)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N18 compound treatment 17655.3 413.0 0.37 0.3728 1.0 2065844 ICCB6_000304 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N19 compound treatment 17046.3 -196.0 -0.18 -0.1771 -1.0 1952631 ICCB6_000305 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N20 compound treatment 17808.2 566.0 0.51 0.5109 1.0 2065845 ICCB6_000306 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N21 compound treatment 17855.9 613.0 0.55 0.5539 1.0 3005761 ICCB6_000307 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N22 compound treatment 17595.0 353.0 0.32 0.3184 1.0 2065846 ICCB6_000308 CN(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)Cc8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N23 mock treatment 17521.7 279.0 0.25 0.2522 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 N24 mock treatment 17448.5 206.0 0.19 0.1861 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O01 compound treatment 16667.1 -575.0 -0.52 -0.5195 -1.0 2065847 ICCB6_000309 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3cccc(F)c3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O02 compound treatment 16924.9 -318.0 -0.29 -0.2868 -1.0 3176588 ICCB6_000310 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)NCc5ccc(Cl)c(Cl)c5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O03 compound treatment 17748.2 506.0 0.46 0.4567 1.0 2065848 ICCB6_000311 Cc1ccc(cc1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O04 compound treatment 16415.6 -827.0 -0.75 -0.7467 -1.0 3176589 ICCB6_000312 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCc5ccc(cc5)[N+](=O)[O-])c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O05 compound treatment 18045.7 803.0 0.73 0.7253 1.0 2065849 ICCB6_000313 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)CCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O06 compound treatment 16886.1 -356.0 -0.32 -0.3218 -1.0 2065850 ICCB6_000314 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(Br)cc4)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O07 compound treatment 16801.2 -441.0 -0.4 -0.3985 -1.0 2065851 ICCB6_000315 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O08 compound treatment 17612.7 370.0 0.33 0.3343 1.0 2065852 ICCB6_000316 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(cc4)[N+](=O)[O-])cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O09 compound treatment 17333.7 91.2 0.08 0.0824 1.0 2065853 ICCB6_000317 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O10 compound treatment 17436.2 194.0 0.17 0.175 1.0 2065854 ICCB6_000318 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O11 compound treatment 17287.5 45.0 0.04 0.0407 1.0 2065855 ICCB6_000319 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O12 compound treatment 17210.9 -31.6 -0.03 -0.0285 -1.0 2065856 ICCB6_000320 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O13 compound treatment 18138.8 896.0 0.81 0.8094 1.0 1952450 ICCB6_000321 CCOC(=O)C(O)C(O)c1ccc(CO[Si](C(C)C)(C(C)C)c2ccccc2)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O14 compound treatment 18024.0 782.0 0.71 0.7057 1.0 2065857 ICCB6_000322 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O15 compound treatment 17385.4 143.0 0.13 0.1291 1.0 1952761 ICCB6_000323 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O16 compound treatment 17350.7 108.0 0.1 0.0977 1.0 2065858 ICCB6_000324 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O17 compound treatment 17075.8 -167.0 -0.15 -0.1505 -1.0 1952837 ICCB6_000325 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O18 compound treatment 17481.7 239.0 0.22 0.216 1.0 2065859 ICCB6_000326 CO[C@H]1O[C@@H]2COC(O[C@H]2[C@H](OC(=O)/C=C/C=C/C)[C@H]1OC(=O)/C=C/C=C/C)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O19 compound treatment 17608.2 366.0 0.33 0.3303 1.0 1952633 ICCB6_000327 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O20 compound treatment 16693.3 -549.0 -0.5 -0.4959 -1.0 2065860 ICCB6_000328 CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COC(c2ccccc2)(c3ccccc3)c4ccccc4)O[C@H](CC=C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1N=[N+]=[N-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O21 compound treatment 18140.0 898.0 0.81 0.8105 1.0 1952755 ICCB6_000329 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O22 compound treatment 16694.4 -548.0 -0.49 -0.4949 -1.0 2065861 ICCB6_000330 C[C@H]1[C@H](OC(=O)N1C(=O)[C@@H](CC=C)C(C)(C)C)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O23 mock treatment 17382.8 140.0 0.13 0.1267 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 O24 mock treatment 16276.7 -966.0 -0.87 -0.8721 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P01 compound treatment 16460.0 -782.0 -0.71 -0.7066 -1.0 2065862 ICCB6_000331 CC1(C)OCC2=C(CC(CCc3ccccc3)OC2CCc4ccccc4)O1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P02 compound treatment 17467.4 225.0 0.2 0.2031 1.0 2065863 ICCB6_000332 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P03 compound treatment 17494.9 252.0 0.23 0.228 1.0 2065864 ICCB6_000333 C1CCC(CC1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P04 compound treatment 17276.4 33.9 0.03 0.0307 1.0 2065865 ICCB6_000334 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P05 compound treatment 16699.6 -543.0 -0.49 -0.4902 -1.0 2065866 ICCB6_000335 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccc(OC)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P06 compound treatment 17235.7 -6.75 -0.01 -0.0061 -1.0 2065867 ICCB6_000336 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P07 compound treatment 17184.6 -57.9 -0.05 -0.0522 -1.0 2065868 ICCB6_000337 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P08 compound treatment 17287.7 45.2 0.04 0.0409 1.0 2065869 ICCB6_000338 C[C@H](Cc1ccccc1)N(C)CC#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P09 compound treatment 17408.4 166.0 0.15 0.1499 1.0 2065870 ICCB6_000339 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P10 compound treatment 18062.6 820.0 0.74 0.7406 1.0 2065871 ICCB6_000340 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P11 compound treatment 16607.3 -635.0 -0.57 -0.5735 -1.0 2065872 ICCB6_000341 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P12 compound treatment 18181.7 939.0 0.85 0.8481 1.0 2065873 ICCB6_000342 CCOC(OCC)C#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P13 compound treatment 18245.5 1000.0 0.91 0.9058 1.0 2065874 ICCB6_000343 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P14 compound treatment 15329.2 -1910.0 -1.73 -1.7277 -1.0 2065875 ICCB6_000344 Brc1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P15 compound treatment 17895.8 653.0 0.59 0.59 1.0 1952804 ICCB6_000345 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P16 compound treatment 15762.9 -1480.0 -1.34 -1.336 -1.0 2065876 ICCB6_000346 CCOC(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P17 compound treatment 17582.2 340.0 0.31 0.3068 1.0 1952838 ICCB6_000347 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P18 compound treatment 18063.5 821.0 0.74 0.7414 1.0 2065877 ICCB6_000348 O=C(/C=C\1/C(=O)Nc2ccccc12)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P19 compound treatment 18258.9 1020.0 0.92 0.9179 1.0 1952634 ICCB6_000349 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P20 compound treatment 16718.6 -524.0 -0.47 -0.473 -1.0 2065878 ICCB6_000350 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P21 compound treatment 17103.1 -139.0 -0.13 -0.1258 -1.0 1952770 ICCB6_000351 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P22 compound treatment 16386.6 -856.0 -0.77 -0.7728 -1.0 2065879 ICCB6_000352 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P23 mock treatment 17358.0 116.0 0.1 0.1043 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.1463 P24 mock treatment 16260.1 -982.0 -0.89 -0.8871 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A01 mock treatment 17771.3 -62.1 -0.06 -0.0561 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A02 mock treatment 17887.4 54.0 0.05 0.0488 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A03 compound treatment 17723.2 -110.0 -0.1 -0.0995 -1.0 3000673 BCB01_000001 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A04 compound treatment 18476.2 643.0 0.58 0.5805 1.0 3000674 BCB01_000002 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A05 compound treatment 18100.8 267.0 0.24 0.2415 1.0 3000675 BCB01_000003 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A06 compound treatment 17973.3 140.0 0.13 0.1264 1.0 3000676 BCB01_000004 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A07 compound treatment 17761.3 -72.1 -0.07 -0.0651 -1.0 3093034 BCB01_000005 COc1cc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A08 compound treatment 17468.9 -364.0 -0.33 -0.3291 -1.0 3000677 BCB01_000006 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A09 compound treatment 18818.3 985.0 0.89 0.8894 1.0 3093035 BCB01_000007 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A10 compound treatment 18055.7 222.0 0.2 0.2008 1.0 3000678 BCB01_000008 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A11 compound treatment 17553.4 -280.0 -0.25 -0.2528 -1.0 3093104 BCB01_000009 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A12 compound treatment 18226.1 393.0 0.35 0.3546 1.0 3093105 BCB01_000010 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A13 compound treatment 17372.9 -460.0 -0.42 -0.4158 -1.0 3000679 BCB01_000011 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A14 compound treatment 17578.8 -255.0 -0.23 -0.2299 -1.0 3093106 BCB01_000012 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A15 compound treatment 17864.8 31.4 0.03 0.0284 1.0 3093107 BCB01_000013 CCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A16 compound treatment 18027.1 194.0 0.17 0.1749 1.0 3000680 BCB01_000014 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A17 compound treatment 17261.7 -572.0 -0.52 -0.5162 -1.0 3093108 BCB01_000015 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C)C3=O)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A18 compound treatment 17270.7 -563.0 -0.51 -0.5081 -1.0 3093109 BCB01_000016 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A19 compound treatment 17336.4 -497.0 -0.45 -0.4488 -1.0 3000681 BCB01_000017 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C)C3=O)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A20 compound treatment 17115.1 -718.0 -0.65 -0.6486 -1.0 3093110 BCB01_000018 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A21 compound treatment 17937.7 104.0 0.09 0.0942 1.0 3000682 BCB01_000019 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A22 compound treatment 17408.8 -425.0 -0.38 -0.3834 -1.0 3093111 BCB01_000020 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A23 mock treatment 17756.2 -77.2 -0.07 -0.0697 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 A24 mock treatment 17440.4 -393.0 -0.35 -0.3549 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B01 mock treatment 17518.0 -315.0 -0.28 -0.2848 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B02 mock treatment 18963.1 1130.0 1.02 1.0202 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B03 compound treatment 18248.7 415.0 0.38 0.375 1.0 3093112 BCB01_000021 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B04 compound treatment 17849.7 16.3 0.01 0.0147 1.0 3000683 BCB01_000022 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B05 compound treatment 18099.8 266.0 0.24 0.2406 1.0 3093113 BCB01_000023 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B06 compound treatment 17997.1 164.0 0.15 0.1478 1.0 3093114 BCB01_000024 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B07 compound treatment 18295.2 462.0 0.42 0.417 1.0 3000684 BCB01_000025 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B08 compound treatment 18484.5 651.0 0.59 0.588 1.0 3093115 BCB01_000026 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B09 compound treatment 18430.0 597.0 0.54 0.5388 1.0 3093116 BCB01_000027 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B10 compound treatment 18292.3 459.0 0.41 0.4144 1.0 3000685 BCB01_000028 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B11 compound treatment 18204.6 371.0 0.34 0.3352 1.0 3093117 BCB01_000029 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(C)cc(C)cc4C)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B12 compound treatment 18003.5 170.0 0.15 0.1536 1.0 3093118 BCB01_000030 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B13 compound treatment 17963.9 131.0 0.12 0.1179 1.0 3000686 BCB01_000031 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4C)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B14 compound treatment 18284.7 451.0 0.41 0.4076 1.0 3093119 BCB01_000032 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccco4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B15 compound treatment 18062.4 229.0 0.21 0.2068 1.0 3093120 BCB01_000033 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(c4ccccc4)c5ccccc5)C(=O)N(C3=O)c6ccccc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B16 compound treatment 17348.4 -485.0 -0.44 -0.4379 -1.0 3000687 BCB01_000034 CCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B17 compound treatment 18428.7 595.0 0.54 0.5376 1.0 3000688 BCB01_000035 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B18 compound treatment 17840.0 6.63 0.01 0.006 1.0 3093121 BCB01_000036 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B19 compound treatment 16985.9 -847.0 -0.77 -0.7653 -1.0 3093122 BCB01_000037 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B20 compound treatment 17961.9 129.0 0.12 0.1161 1.0 3093123 BCB01_000038 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(F)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B21 compound treatment 17790.6 -42.8 -0.04 -0.0386 -1.0 3000689 BCB01_000039 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B22 compound treatment 18027.6 194.0 0.18 0.1754 1.0 3093124 BCB01_000040 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B23 mock treatment 17384.5 -449.0 -0.41 -0.4053 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 B24 mock treatment 17271.2 -562.0 -0.51 -0.5076 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C01 mock treatment 17301.7 -532.0 -0.48 -0.4801 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C02 mock treatment 18256.5 423.0 0.38 0.3821 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C03 compound treatment 17469.7 -364.0 -0.33 -0.3284 -1.0 3000690 BCB01_000041 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C)C3=O)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C04 compound treatment 18513.6 680.0 0.61 0.6142 1.0 3093125 BCB01_000042 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C05 compound treatment 18125.4 292.0 0.26 0.2637 1.0 3093282 BCB01_000043 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C)C3=O)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C06 compound treatment 17042.0 -791.0 -0.71 -0.7146 -1.0 3000691 BCB01_000044 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C07 compound treatment 17355.5 -478.0 -0.43 -0.4315 -1.0 3093194 BCB01_000045 COc1cc(NN2C3C(C=CC2C(O)C4CCC(CC4)C(=C)C)C(=O)N(C)C3=O)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C08 compound treatment 18335.1 502.0 0.45 0.4531 1.0 3093195 BCB01_000046 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C09 compound treatment 18032.4 199.0 0.18 0.1797 1.0 3000692 BCB01_000047 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C)C3=O)cc(OC)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C10 compound treatment 18222.9 390.0 0.35 0.3517 1.0 3093196 BCB01_000048 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)/C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C11 compound treatment 17370.4 -463.0 -0.42 -0.4181 -1.0 3093197 BCB01_000049 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C12 compound treatment 18329.1 496.0 0.45 0.4476 1.0 3000693 BCB01_000050 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C13 compound treatment 18013.5 180.0 0.16 0.1627 1.0 3093198 BCB01_000051 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C14 compound treatment 17329.6 -504.0 -0.45 -0.4549 -1.0 3000694 BCB01_000052 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C15 compound treatment 17867.3 33.9 0.03 0.0306 1.0 3093199 BCB01_000053 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C16 compound treatment 17764.7 -68.7 -0.06 -0.062 -1.0 3093200 BCB01_000054 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C17 compound treatment 18272.8 439.0 0.4 0.3968 1.0 3000695 BCB01_000055 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C18 compound treatment 17648.8 -185.0 -0.17 -0.1667 -1.0 3093201 BCB01_000056 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C19 compound treatment 17799.4 -34.0 -0.03 -0.0307 -1.0 3093202 BCB01_000057 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C20 compound treatment 16378.5 -1450.0 -1.31 -1.3138 -1.0 3000696 BCB01_000058 COc1ccc(cc1)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C21 compound treatment 17831.6 -1.77 0.0 -0.0016 -1.0 3093203 BCB01_000059 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C22 compound treatment 17086.8 -747.0 -0.67 -0.6742 -1.0 3093204 BCB01_000060 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C23 mock treatment 17977.9 145.0 0.13 0.1305 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 C24 mock treatment 17078.5 -755.0 -0.68 -0.6817 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D01 mock treatment 18557.6 724.0 0.65 0.654 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D02 mock treatment 18451.3 618.0 0.56 0.558 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D03 compound treatment 18808.2 975.0 0.88 0.8803 1.0 3000697 BCB01_000061 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccc(O)c4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D04 compound treatment 18787.4 954.0 0.86 0.8615 1.0 3093205 BCB01_000062 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D05 compound treatment 17103.0 -730.0 -0.66 -0.6595 -1.0 3093206 BCB01_000063 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)B(O)O)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D06 compound treatment 17633.8 -200.0 -0.18 -0.1802 -1.0 3000698 BCB01_000064 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccn4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D07 compound treatment 18054.4 221.0 0.2 0.1996 1.0 3093207 BCB01_000065 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cn(C(=O)C)c5ccccc45)C(=O)N(C3=O)c6ccccc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D08 compound treatment 18527.3 694.0 0.63 0.6266 1.0 3000792 BCB01_000066 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D09 compound treatment 18651.4 818.0 0.74 0.7387 1.0 3000794 BCB01_000067 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(C)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D10 compound treatment 19226.9 1390.0 1.26 1.2584 1.0 3000796 BCB01_000068 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D11 compound treatment 18367.1 534.0 0.48 0.482 1.0 3000797 BCB01_000069 CC(C)c1ccc(NN2C3C(C=CC2C(O)CC(C)c4ccc(C)o4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D12 compound treatment 18611.2 778.0 0.7 0.7024 1.0 3093208 BCB01_000070 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4c(F)cccc4Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D13 compound treatment 18075.8 242.0 0.22 0.2189 1.0 3093209 BCB01_000071 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccs4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D14 compound treatment 17984.2 151.0 0.14 0.1362 1.0 3000798 BCB01_000072 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D15 compound treatment 18242.7 409.0 0.37 0.3696 1.0 3093210 BCB01_000073 CC(C)c1ccc(NN2C3C(C=CC2C(O)Cc4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D16 compound treatment 18422.7 589.0 0.53 0.5322 1.0 3000800 BCB01_000074 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D17 compound treatment 18735.7 902.0 0.81 0.8148 1.0 3093211 BCB01_000075 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D18 compound treatment 18181.2 348.0 0.31 0.3141 1.0 3000876 BCB01_000076 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c(C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D19 compound treatment 17197.1 -636.0 -0.57 -0.5746 -1.0 3000877 BCB01_000077 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc5OCOc5c4)C(=O)N(C3=O)c6ccccc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D20 compound treatment 17815.7 -17.7 -0.02 -0.016 -1.0 3000878 BCB01_000078 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D21 compound treatment 17549.1 -284.0 -0.26 -0.2567 -1.0 3000880 BCB01_000079 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4=C[C@H]5C[C@@H](C4)C5(C)C)C(=O)N(C3=O)c6ccccc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D22 compound treatment 17643.9 -189.0 -0.17 -0.1711 -1.0 3093212 BCB01_000080 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D23 mock treatment 17887.0 53.6 0.05 0.0484 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 D24 mock treatment 17225.6 -608.0 -0.55 -0.5488 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E01 mock treatment 18448.4 615.0 0.56 0.5554 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E02 mock treatment 17890.0 56.6 0.05 0.0511 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E03 compound treatment 17958.5 125.0 0.11 0.113 1.0 3000882 BCB01_000081 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E04 compound treatment 18201.5 368.0 0.33 0.3324 1.0 3093213 BCB01_000082 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E05 compound treatment 16761.4 -1070.0 -0.97 -0.968 -1.0 3093214 BCB01_000083 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E06 compound treatment 17980.7 147.0 0.13 0.133 1.0 3000884 BCB01_000084 CN1C(=O)C2C=CC(C(O)C3CCC(CC3)C(=C)C)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E07 compound treatment 17000.9 -832.0 -0.75 -0.7517 -1.0 3093215 BCB01_000085 CN1C(=O)C2C=CC(C(O)c3ccco3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E08 compound treatment 18004.3 171.0 0.15 0.1543 1.0 3093216 BCB01_000086 CCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E09 compound treatment 17778.8 -54.6 -0.05 -0.0493 -1.0 3000885 BCB01_000087 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E10 compound treatment 18168.9 336.0 0.3 0.303 1.0 3093283 BCB01_000088 CCCCCCCCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E11 compound treatment 17983.1 150.0 0.14 0.1352 1.0 3093284 BCB01_000089 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E12 compound treatment 17605.3 -228.0 -0.21 -0.206 -1.0 3000886 BCB01_000090 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E13 compound treatment 17576.4 -257.0 -0.23 -0.232 -1.0 3093285 BCB01_000091 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E14 compound treatment 18178.5 345.0 0.31 0.3117 1.0 3093286 BCB01_000092 COc1ccc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c5ccccc15 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E15 compound treatment 18245.2 412.0 0.37 0.3719 1.0 3000889 BCB01_000093 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E16 compound treatment 17865.8 32.4 0.03 0.0293 1.0 3093287 BCB01_000094 COc1cc(Br)cc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c1OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E17 compound treatment 18214.3 381.0 0.34 0.344 1.0 3093288 BCB01_000095 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C)C4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E18 compound treatment 17747.1 -86.3 -0.08 -0.0779 -1.0 3000890 BCB01_000096 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3N5CCCCC5)C(=O)N(C)C4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E19 compound treatment 16597.0 -1240.0 -1.12 -1.1165 -1.0 3093289 BCB01_000097 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E20 compound treatment 16903.9 -929.0 -0.84 -0.8393 -1.0 3093290 BCB01_000098 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E21 compound treatment 17084.1 -749.0 -0.68 -0.6766 -1.0 3000891 BCB01_000099 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E22 compound treatment 16030.8 -1800.0 -1.63 -1.6277 -1.0 3093291 BCB01_000100 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E23 mock treatment 17677.8 -156.0 -0.14 -0.1405 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 E24 mock treatment 17554.4 -279.0 -0.25 -0.2519 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F01 mock treatment 18628.8 795.0 0.72 0.7183 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F02 mock treatment 18437.2 604.0 0.55 0.5453 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F03 compound treatment 17865.3 31.9 0.03 0.0288 1.0 3093292 BCB01_000101 CC(C)c1ccc(NN2C3C(C=CC2C(O)/C=C(\C)/CCC=C(C)C)C(=O)N(C3=O)c4ccccc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F04 compound treatment 18818.3 985.0 0.89 0.8894 1.0 3000892 BCB01_000102 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F05 compound treatment 17815.2 -18.2 -0.02 -0.0164 -1.0 3093293 BCB01_000103 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F06 compound treatment 18166.2 333.0 0.3 0.3005 1.0 3000894 BCB01_000104 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc5ccccc45 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F07 compound treatment 17919.8 86.4 0.08 0.078 1.0 3093294 BCB01_000105 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F08 compound treatment 19187.3 1350.0 1.22 1.2226 1.0 3093295 BCB01_000106 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F09 compound treatment 18466.0 633.0 0.57 0.5713 1.0 3000896 BCB01_000107 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F10 compound treatment 18704.3 871.0 0.79 0.7865 1.0 3093296 BCB01_000108 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F11 compound treatment 18594.7 761.0 0.69 0.6875 1.0 3093297 BCB01_000109 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)C(=O)C)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F12 compound treatment 18095.8 262.0 0.24 0.237 1.0 3000898 BCB01_000110 CC(C)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F13 compound treatment 19387.3 1550.0 1.4 1.4032 1.0 3000979 BCB01_000111 CCCCCCCCCCC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F14 compound treatment 18048.0 215.0 0.19 0.1938 1.0 3000980 BCB01_000112 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc(O)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F15 compound treatment 17642.0 -191.0 -0.17 -0.1728 -1.0 3000981 BCB01_000113 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F16 compound treatment 18240.4 407.0 0.37 0.3675 1.0 3000982 BCB01_000114 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F17 compound treatment 18613.4 780.0 0.7 0.7044 1.0 3000984 BCB01_000115 COc1ccc(C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O)c4ccccc14 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F18 compound treatment 17778.6 -54.8 -0.05 -0.0495 -1.0 3093298 BCB01_000116 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c(C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F19 compound treatment 17774.4 -59.0 -0.05 -0.0533 -1.0 3093299 BCB01_000117 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F20 compound treatment 18378.5 545.0 0.49 0.4923 1.0 3000987 BCB01_000118 CC(=O)N1CC(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F21 compound treatment 17496.4 -337.0 -0.3 -0.3043 -1.0 3093300 BCB01_000119 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F22 compound treatment 17335.1 -498.0 -0.45 -0.4499 -1.0 3093301 BCB01_000120 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccs4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F23 mock treatment 16834.3 -999.0 -0.9 -0.9022 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 F24 mock treatment 17128.3 -705.0 -0.64 -0.6367 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G01 mock treatment 17888.1 54.7 0.05 0.0494 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G02 mock treatment 18298.7 465.0 0.42 0.4202 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G03 compound treatment 17936.8 103.0 0.09 0.0934 1.0 3000990 BCB01_000121 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G04 compound treatment 18003.9 171.0 0.15 0.154 1.0 3093302 BCB01_000122 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G05 compound treatment 18346.2 513.0 0.46 0.4631 1.0 3093303 BCB01_000123 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G06 compound treatment 17585.0 -248.0 -0.22 -0.2243 -1.0 3000991 BCB01_000124 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G07 compound treatment 17484.0 -349.0 -0.32 -0.3155 -1.0 3093304 BCB01_000125 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G08 compound treatment 17788.8 -44.6 -0.04 -0.0403 -1.0 3000992 BCB01_000126 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G09 compound treatment 17682.0 -151.0 -0.14 -0.1367 -1.0 3093373 BCB01_000127 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G10 compound treatment 17659.3 -174.0 -0.16 -0.1572 -1.0 3093374 BCB01_000128 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G11 compound treatment 17175.4 -658.0 -0.59 -0.5942 -1.0 3000993 BCB01_000129 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G12 compound treatment 18133.0 300.0 0.27 0.2706 1.0 3093375 BCB01_000130 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(C2C1=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G13 compound treatment 17021.3 -812.0 -0.73 -0.7333 -1.0 3093376 BCB01_000131 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G14 compound treatment 17504.0 -329.0 -0.3 -0.2974 -1.0 3000994 BCB01_000132 C/C=C/C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G15 compound treatment 17814.4 -19.0 -0.02 -0.0171 -1.0 3093377 BCB01_000133 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G16 compound treatment 18455.4 622.0 0.56 0.5617 1.0 3000995 BCB01_000134 CCC(CC)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G17 compound treatment 18118.1 285.0 0.26 0.2571 1.0 3093378 BCB01_000135 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccco5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G18 compound treatment 18023.2 190.0 0.17 0.1714 1.0 3000996 BCB01_000136 CC(C)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G19 compound treatment 17888.8 55.4 0.05 0.0501 1.0 3093379 BCB01_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G20 compound treatment 17645.8 -188.0 -0.17 -0.1694 -1.0 3093380 BCB01_000138 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G21 compound treatment 18047.2 214.0 0.19 0.1931 1.0 3000997 BCB01_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G22 compound treatment 17501.5 -332.0 -0.3 -0.2997 -1.0 3093381 BCB01_000140 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G23 mock treatment 17614.2 -219.0 -0.2 -0.1979 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 G24 mock treatment 18668.9 836.0 0.75 0.7545 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H01 mock treatment 18143.8 310.0 0.28 0.2803 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H02 mock treatment 18797.6 964.0 0.87 0.8707 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H03 compound treatment 18138.1 305.0 0.28 0.2752 1.0 3000998 BCB01_000141 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H04 compound treatment 19035.7 1200.0 1.09 1.0857 1.0 3093382 BCB01_000142 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H05 compound treatment 17893.7 60.3 0.05 0.0545 1.0 3093383 BCB01_000143 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H06 compound treatment 18595.1 762.0 0.69 0.6878 1.0 3000999 BCB01_000144 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(C#N)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H07 compound treatment 18098.3 265.0 0.24 0.2392 1.0 3093384 BCB01_000145 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H08 compound treatment 18294.7 461.0 0.42 0.4166 1.0 3093385 BCB01_000146 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc5OCOc5c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H09 compound treatment 17658.1 -175.0 -0.16 -0.1583 -1.0 3001000 BCB01_000147 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H10 compound treatment 18194.9 362.0 0.33 0.3265 1.0 3001068 BCB01_000148 CC1(C)[C@H]2CC1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H11 compound treatment 17393.3 -440.0 -0.4 -0.3974 -1.0 3001069 BCB01_000149 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H12 compound treatment 18038.4 205.0 0.19 0.1851 1.0 3001070 BCB01_000150 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H13 compound treatment 17795.2 -38.2 -0.03 -0.0345 -1.0 3001072 BCB01_000151 C/C=C/C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H14 compound treatment 18772.5 939.0 0.85 0.848 1.0 3093386 BCB01_000152 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)/C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H15 compound treatment 18397.6 564.0 0.51 0.5095 1.0 3001073 BCB01_000153 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(NC(=O)OC(C)(C)C)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H16 compound treatment 19060.7 1230.0 1.11 1.1083 1.0 3093387 BCB01_000154 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H17 compound treatment 17741.7 -91.7 -0.08 -0.0828 -1.0 3093388 BCB01_000155 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H18 compound treatment 18425.1 592.0 0.53 0.5343 1.0 3001076 BCB01_000156 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(I)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H19 compound treatment 17725.3 -108.0 -0.1 -0.0976 -1.0 3093389 BCB01_000157 CC(C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H20 compound treatment 17449.3 -384.0 -0.35 -0.3468 -1.0 3093390 BCB01_000158 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H21 compound treatment 17647.9 -185.0 -0.17 -0.1675 -1.0 3001078 BCB01_000159 CC(CC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccc(C)o3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H22 compound treatment 18398.7 565.0 0.51 0.5105 1.0 3093391 BCB01_000160 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H23 mock treatment 17240.3 -593.0 -0.54 -0.5356 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 H24 mock treatment 19571.8 1740.0 1.57 1.5698 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I01 mock treatment 18203.3 370.0 0.33 0.334 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I02 mock treatment 17902.6 69.2 0.06 0.0625 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I03 compound treatment 17964.1 131.0 0.12 0.118 1.0 3001079 BCB01_000161 CN1C(=O)C2C=CC(C(O)c3cccc(O)c3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I04 compound treatment 18251.2 418.0 0.38 0.3773 1.0 3093392 BCB01_000162 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I05 compound treatment 18109.8 276.0 0.25 0.2496 1.0 3093393 BCB01_000163 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I06 compound treatment 18142.6 309.0 0.28 0.2792 1.0 3001081 BCB01_000164 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I07 compound treatment 16740.2 -1090.0 -0.99 -0.9871 -1.0 3093394 BCB01_000165 CN1C(=O)C2C=CC(C(O)c3cn(C(=O)C)c4ccccc34)N(Nc5ccccc5)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I08 compound treatment 17700.8 -133.0 -0.12 -0.1197 -1.0 3093395 BCB01_000166 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I09 compound treatment 17640.4 -193.0 -0.17 -0.1743 -1.0 3001082 BCB01_000167 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I10 compound treatment 18075.6 242.0 0.22 0.2187 1.0 3093464 BCB01_000168 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I11 compound treatment 17297.5 -536.0 -0.48 -0.4839 -1.0 3001083 BCB01_000169 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I12 compound treatment 17974.5 141.0 0.13 0.1274 1.0 3093465 BCB01_000170 CN1C(=O)C2C=CC(C(O)c3cccn3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I13 compound treatment 17779.5 -53.9 -0.05 -0.0486 -1.0 3093466 BCB01_000171 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccc(C)o4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I14 compound treatment 17741.7 -91.7 -0.08 -0.0828 -1.0 3001084 BCB01_000172 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I15 compound treatment 18221.4 388.0 0.35 0.3504 1.0 3093467 BCB01_000173 CN1C(=O)C2C=CC(C(O)c3cccs3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I16 compound treatment 17746.8 -86.6 -0.08 -0.0782 -1.0 3093468 BCB01_000174 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I17 compound treatment 16848.5 -985.0 -0.89 -0.8893 -1.0 3001085 BCB01_000175 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I18 compound treatment 17718.4 -115.0 -0.1 -0.1038 -1.0 3093469 BCB01_000176 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I19 compound treatment 16876.9 -956.0 -0.86 -0.8637 -1.0 3001086 BCB01_000177 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccccc5)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I20 compound treatment 17548.5 -285.0 -0.26 -0.2572 -1.0 3093470 BCB01_000178 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I21 compound treatment 17698.5 -135.0 -0.12 -0.1218 -1.0 3001087 BCB01_000179 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I22 compound treatment 16943.6 -890.0 -0.8 -0.8035 -1.0 3093471 BCB01_000180 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I23 mock treatment 17524.9 -308.0 -0.28 -0.2786 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 I24 mock treatment 17238.6 -595.0 -0.54 -0.5371 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J01 mock treatment 18114.8 281.0 0.25 0.2541 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J02 mock treatment 18503.8 670.0 0.61 0.6054 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J03 compound treatment 18598.8 765.0 0.69 0.6912 1.0 3093472 BCB01_000181 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J04 compound treatment 18379.1 546.0 0.49 0.4928 1.0 3001088 BCB01_000182 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J05 compound treatment 17993.6 160.0 0.14 0.1447 1.0 3093473 BCB01_000183 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J06 compound treatment 18085.4 252.0 0.23 0.2276 1.0 3093474 BCB01_000184 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J07 compound treatment 18387.4 554.0 0.5 0.5003 1.0 3001089 BCB01_000185 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J08 compound treatment 19376.0 1540.0 1.39 1.393 1.0 3001153 BCB01_000186 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J09 compound treatment 18436.2 603.0 0.54 0.5444 1.0 3001154 BCB01_000187 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J10 compound treatment 17694.4 -139.0 -0.13 -0.1255 -1.0 3001156 BCB01_000188 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J11 compound treatment 18573.5 740.0 0.67 0.6683 1.0 3001157 BCB01_000189 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J12 compound treatment 17779.3 -54.1 -0.05 -0.0488 -1.0 3093475 BCB01_000190 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccco4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J13 compound treatment 17599.9 -233.0 -0.21 -0.2108 -1.0 3093476 BCB01_000191 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J14 compound treatment 18186.0 353.0 0.32 0.3184 1.0 3001159 BCB01_000192 CCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J15 compound treatment 17728.5 -105.0 -0.09 -0.0947 -1.0 3093477 BCB01_000193 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J16 compound treatment 18446.6 613.0 0.55 0.5537 1.0 3001160 BCB01_000194 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J17 compound treatment 17842.2 8.83 0.01 0.008 1.0 3093478 BCB01_000195 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J18 compound treatment 17863.6 30.2 0.03 0.0273 1.0 3093479 BCB01_000196 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(F)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J19 compound treatment 17580.8 -253.0 -0.23 -0.2281 -1.0 3001161 BCB01_000197 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J20 compound treatment 17589.4 -244.0 -0.22 -0.2203 -1.0 3093480 BCB01_000198 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J21 compound treatment 18280.4 447.0 0.4 0.4037 1.0 3093481 BCB01_000199 CCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J22 compound treatment 17538.7 -295.0 -0.27 -0.2661 -1.0 3001163 BCB01_000200 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J23 mock treatment 17991.7 158.0 0.14 0.143 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 J24 mock treatment 18115.7 282.0 0.25 0.2549 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K01 mock treatment 18451.3 618.0 0.56 0.558 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K02 mock treatment 18135.0 302.0 0.27 0.2724 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K03 compound treatment 18679.4 846.0 0.76 0.764 1.0 3093482 BCB01_000201 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccccc4)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K04 compound treatment 18504.6 671.0 0.61 0.6061 1.0 3001164 BCB01_000202 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K05 compound treatment 16351.6 -1480.0 -1.34 -1.3381 -1.0 3093483 BCB01_000203 CN1C(=O)C2C=CC(C(O)/C=C(\C)/CCC=C(C)C)N(Nc3ccccc3)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K06 compound treatment 16610.1 -1220.0 -1.1 -1.1046 -1.0 3093484 BCB01_000204 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K07 compound treatment 16930.9 -902.0 -0.81 -0.8149 -1.0 3000112 BCB01_000205 CN1C(=O)C2C=CC(C(O)C(C)(C)C)N(Nc3ccccc3)C2C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K08 compound treatment 17270.3 -563.0 -0.51 -0.5085 -1.0 3000114 BCB01_000206 COc1ccc(cc1)C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K09 compound treatment 17775.6 -57.8 -0.05 -0.0522 -1.0 3000115 BCB01_000207 CCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K10 compound treatment 17806.8 -26.6 -0.02 -0.024 -1.0 3000116 BCB01_000208 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K11 compound treatment 16674.3 -1160.0 -1.05 -1.0467 -1.0 3000118 BCB01_000209 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K12 compound treatment 17067.9 -765.0 -0.69 -0.6912 -1.0 3093485 BCB01_000210 CCCCC(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K13 compound treatment 17647.5 -186.0 -0.17 -0.1678 -1.0 3093645 BCB01_000211 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K14 compound treatment 18462.7 629.0 0.57 0.5683 1.0 3000120 BCB01_000212 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K15 compound treatment 17399.0 -434.0 -0.39 -0.3922 -1.0 3093555 BCB01_000213 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K16 compound treatment 17999.9 167.0 0.15 0.1504 1.0 3093556 BCB01_000214 COc1ccc(C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K17 compound treatment 17255.0 -578.0 -0.52 -0.5223 -1.0 3000122 BCB01_000215 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K18 compound treatment 17806.8 -26.6 -0.02 -0.024 -1.0 3093557 BCB01_000216 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K19 compound treatment 17593.5 -240.0 -0.22 -0.2166 -1.0 3000123 BCB01_000217 OC(C#Cc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K20 compound treatment 17713.2 -120.0 -0.11 -0.1085 -1.0 3093558 BCB01_000218 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(C2C1=O)N(c5ccccc5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K21 compound treatment 17140.6 -693.0 -0.63 -0.6256 -1.0 3093559 BCB01_000219 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K22 compound treatment 17647.5 -186.0 -0.17 -0.1678 -1.0 3000124 BCB01_000220 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K23 mock treatment 17318.7 -515.0 -0.46 -0.4648 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 K24 mock treatment 17699.0 -134.0 -0.12 -0.1213 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L01 mock treatment 17907.2 73.8 0.07 0.0667 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L02 mock treatment 17818.3 -15.1 -0.01 -0.0136 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L03 compound treatment 17999.2 166.0 0.15 0.1497 1.0 3093560 BCB01_000221 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L04 compound treatment 18476.5 643.0 0.58 0.5807 1.0 3093561 BCB01_000222 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L05 compound treatment 17832.4 -0.974 0.0 -9.0E-4 -1.0 3000127 BCB01_000223 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L06 compound treatment 18659.6 826.0 0.75 0.7461 1.0 3093562 BCB01_000224 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L07 compound treatment 17314.8 -519.0 -0.47 -0.4683 -1.0 3093563 BCB01_000225 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L08 compound treatment 18030.2 197.0 0.18 0.1777 1.0 3000128 BCB01_000226 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L09 compound treatment 16952.4 -881.0 -0.8 -0.7955 -1.0 3093564 BCB01_000227 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L10 compound treatment 17982.9 150.0 0.14 0.135 1.0 3000129 BCB01_000228 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4c(F)cccc4Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L11 compound treatment 17092.3 -741.0 -0.67 -0.6692 -1.0 3093565 BCB01_000229 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L12 compound treatment 17540.6 -293.0 -0.26 -0.2644 -1.0 3093566 BCB01_000230 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L13 compound treatment 17766.7 -66.7 -0.06 -0.0602 -1.0 3000131 BCB01_000231 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L14 compound treatment 17356.0 -477.0 -0.43 -0.4311 -1.0 3093567 BCB01_000232 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L15 compound treatment 17775.7 -57.7 -0.05 -0.0521 -1.0 3093568 BCB01_000233 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L16 compound treatment 17822.5 -10.9 -0.01 -0.0098 -1.0 3000133 BCB01_000234 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c(C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L17 compound treatment 17884.0 50.6 0.05 0.0457 1.0 3093569 BCB01_000235 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L18 compound treatment 17078.8 -755.0 -0.68 -0.6814 -1.0 3000205 BCB01_000236 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L19 compound treatment 17938.2 105.0 0.09 0.0947 1.0 3000206 BCB01_000237 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L20 compound treatment 16740.8 -1090.0 -0.99 -0.9866 -1.0 3000207 BCB01_000238 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L21 compound treatment 16746.2 -1090.0 -0.98 -0.9817 -1.0 3000208 BCB01_000239 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L22 compound treatment 17479.8 -354.0 -0.32 -0.3193 -1.0 3093570 BCB01_000240 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L23 mock treatment 16831.4 -1000.0 -0.9 -0.9048 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 L24 mock treatment 18240.9 408.0 0.37 0.368 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M01 mock treatment 18323.2 490.0 0.44 0.4423 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M02 mock treatment 17750.6 -82.8 -0.07 -0.0747 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M03 compound treatment 17805.4 -28.0 -0.03 -0.0253 -1.0 3000209 BCB01_000241 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M04 compound treatment 18237.6 404.0 0.37 0.365 1.0 3093571 BCB01_000242 C/C=C/C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M05 compound treatment 18147.1 314.0 0.28 0.2833 1.0 3093572 BCB01_000243 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M06 compound treatment 17922.2 88.8 0.08 0.0802 1.0 3000211 BCB01_000244 CC(C)C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M07 compound treatment 16198.4 -1630.0 -1.48 -1.4764 -1.0 3093573 BCB01_000245 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M08 compound treatment 17852.0 18.6 0.02 0.0168 1.0 3093574 BCB01_000246 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M09 compound treatment 17400.4 -433.0 -0.39 -0.391 -1.0 3000213 BCB01_000247 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M10 compound treatment 16482.4 -1350.0 -1.22 -1.2199 -1.0 3093575 BCB01_000248 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M11 compound treatment 16880.0 -953.0 -0.86 -0.8609 -1.0 3000215 BCB01_000249 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M12 compound treatment 17641.8 -192.0 -0.17 -0.173 -1.0 3093576 BCB01_000250 CC(C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M13 compound treatment 17006.4 -827.0 -0.75 -0.7468 -1.0 3093646 BCB01_000251 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M14 compound treatment 17281.0 -552.0 -0.5 -0.4988 -1.0 3000219 BCB01_000252 CN1C(=O)C2C=CC(C(O)c3cccs3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M15 compound treatment 17661.0 -172.0 -0.16 -0.1557 -1.0 3093647 BCB01_000253 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M16 compound treatment 17763.8 -69.6 -0.06 -0.0628 -1.0 3000221 BCB01_000254 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M17 compound treatment 16956.9 -876.0 -0.79 -0.7915 -1.0 3093648 BCB01_000255 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M18 compound treatment 17857.2 23.8 0.02 0.0215 1.0 3093649 BCB01_000256 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M19 compound treatment 16909.0 -924.0 -0.83 -0.8347 -1.0 3000223 BCB01_000257 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M20 compound treatment 17445.7 -388.0 -0.35 -0.3501 -1.0 3093650 BCB01_000258 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M21 compound treatment 17814.6 -18.8 -0.02 -0.017 -1.0 3093651 BCB01_000259 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M22 compound treatment 15873.2 -1960.0 -1.77 -1.7701 -1.0 3000225 BCB01_000260 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M23 mock treatment 16403.6 -1430.0 -1.29 -1.2911 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 M24 mock treatment 17615.8 -218.0 -0.2 -0.1965 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N01 mock treatment 18261.7 428.0 0.39 0.3868 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N02 mock treatment 17771.1 -62.3 -0.06 -0.0562 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N03 compound treatment 18369.6 536.0 0.48 0.4842 1.0 3093652 BCB01_000261 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N04 compound treatment 17410.2 -423.0 -0.38 -0.3821 -1.0 3093653 BCB01_000262 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccc5ccccc45 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N05 compound treatment 17984.8 151.0 0.14 0.1367 1.0 3000227 BCB01_000263 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N06 compound treatment 18231.1 398.0 0.36 0.3591 1.0 3093654 BCB01_000264 C/C=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N07 compound treatment 18315.3 482.0 0.44 0.4352 1.0 3093655 BCB01_000265 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N08 compound treatment 18366.5 533.0 0.48 0.4814 1.0 3000229 BCB01_000266 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N09 compound treatment 18046.2 213.0 0.19 0.1922 1.0 3093656 BCB01_000267 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N10 compound treatment 17091.5 -742.0 -0.67 -0.6699 -1.0 3000231 BCB01_000268 CC(C)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N11 compound treatment 17369.8 -464.0 -0.42 -0.4186 -1.0 3093657 BCB01_000269 CC(C)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N12 compound treatment 17589.4 -244.0 -0.22 -0.2203 -1.0 3000297 BCB01_000270 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N13 compound treatment 17144.5 -689.0 -0.62 -0.6221 -1.0 3000298 BCB01_000271 OB(O)c1ccc(cc1)C(O)C2C=CC3CN(C(=O)C3N2Nc4ccc(C#N)cc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N14 compound treatment 17399.6 -434.0 -0.39 -0.3917 -1.0 3000299 BCB01_000272 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N15 compound treatment 18077.2 244.0 0.22 0.2202 1.0 3093658 BCB01_000273 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N16 compound treatment 17701.3 -132.0 -0.12 -0.1193 -1.0 3093659 BCB01_000274 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N17 compound treatment 17592.6 -241.0 -0.22 -0.2174 -1.0 3000301 BCB01_000275 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N18 compound treatment 17983.9 151.0 0.14 0.1359 1.0 3093660 BCB01_000276 CC(C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N19 compound treatment 16889.4 -944.0 -0.85 -0.8524 -1.0 3093661 BCB01_000277 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N20 compound treatment 17867.0 33.6 0.03 0.0304 1.0 3000302 BCB01_000278 CC(CC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C)o4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N21 compound treatment 17663.7 -170.0 -0.15 -0.1532 -1.0 3093662 BCB01_000279 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N22 compound treatment 17542.3 -291.0 -0.26 -0.2628 -1.0 3093663 BCB01_000280 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccs4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N23 mock treatment 16190.0 -1640.0 -1.48 -1.484 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 N24 mock treatment 18037.7 204.0 0.18 0.1845 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O01 mock treatment 17573.5 -260.0 -0.23 -0.2347 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O02 mock treatment 16054.7 -1780.0 -1.61 -1.6062 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O03 compound treatment 18590.2 757.0 0.68 0.6834 1.0 3000303 BCB01_000281 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O04 compound treatment 17753.6 -79.8 -0.07 -0.072 -1.0 3093664 BCB01_000282 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O05 compound treatment 18111.4 278.0 0.25 0.2511 1.0 3093665 BCB01_000283 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O06 compound treatment 17638.5 -195.0 -0.18 -0.176 -1.0 3000304 BCB01_000284 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O07 compound treatment 17350.2 -483.0 -0.44 -0.4363 -1.0 3093666 BCB01_000285 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O08 compound treatment 17422.7 -411.0 -0.37 -0.3708 -1.0 3093667 BCB01_000286 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)C(=O)C)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O09 compound treatment 18287.4 454.0 0.41 0.41 1.0 3000307 BCB01_000287 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O10 compound treatment 17207.1 -626.0 -0.57 -0.5655 -1.0 3093736 BCB01_000288 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O11 compound treatment 16603.8 -1230.0 -1.11 -1.1103 -1.0 3000308 BCB01_000289 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O12 compound treatment 16690.3 -1140.0 -1.03 -1.0322 -1.0 3093737 BCB01_000290 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O13 compound treatment 16822.6 -1010.0 -0.91 -0.9127 -1.0 3093738 BCB01_000291 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O14 compound treatment 16503.9 -1330.0 -1.2 -1.2005 -1.0 3000310 BCB01_000292 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O15 compound treatment 17051.7 -782.0 -0.71 -0.7059 -1.0 3093739 BCB01_000293 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O16 compound treatment 18247.3 414.0 0.37 0.3738 1.0 3000311 BCB01_000294 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O17 compound treatment 17507.8 -326.0 -0.29 -0.294 -1.0 3093740 BCB01_000295 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O18 compound treatment 17922.7 89.3 0.08 0.0807 1.0 3093741 BCB01_000296 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O19 compound treatment 17648.2 -185.0 -0.17 -0.1672 -1.0 3000313 BCB01_000297 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O20 compound treatment 17125.6 -708.0 -0.64 -0.6391 -1.0 3093742 BCB01_000298 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O21 compound treatment 17854.8 21.4 0.02 0.0193 1.0 3000315 BCB01_000299 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O22 compound treatment 17311.1 -522.0 -0.47 -0.4716 -1.0 3093743 BCB01_000300 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)C(C)C)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O23 mock treatment 17495.3 -338.0 -0.31 -0.3053 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 O24 mock treatment 18373.4 540.0 0.49 0.4876 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P01 mock treatment 17700.6 -133.0 -0.12 -0.1199 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P02 mock treatment 17340.9 -492.0 -0.44 -0.4447 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P03 compound treatment 18180.3 347.0 0.31 0.3133 1.0 3000135 BCB01_000301 CC(C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P04 compound treatment 17494.4 -339.0 -0.31 -0.3061 -1.0 3000137 BCB01_000302 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P05 compound treatment 18079.2 246.0 0.22 0.222 1.0 3000138 BCB01_000303 CC(CC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P06 compound treatment 17959.6 126.0 0.11 0.114 1.0 3000139 BCB01_000304 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C#N)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P07 compound treatment 17227.0 -606.0 -0.55 -0.5476 -1.0 3093744 BCB01_000305 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P08 compound treatment 17988.1 155.0 0.14 0.1397 1.0 3000141 BCB01_000306 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc5OCOc5c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P09 compound treatment 17870.8 37.4 0.03 0.0338 1.0 3093745 BCB01_000307 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P10 compound treatment 18701.4 868.0 0.78 0.7838 1.0 3093746 BCB01_000308 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(Br)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P11 compound treatment 17364.3 -469.0 -0.42 -0.4236 -1.0 3000143 BCB01_000309 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P12 compound treatment 17361.7 -472.0 -0.43 -0.4259 -1.0 3093747 BCB01_000310 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P13 compound treatment 17507.3 -326.0 -0.29 -0.2944 -1.0 3093748 BCB01_000311 CC(=CCC/C=C(\C)/C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P14 compound treatment 17810.7 -22.7 -0.02 -0.0205 -1.0 3000145 BCB01_000312 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)/C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P15 compound treatment 17145.9 -687.0 -0.62 -0.6208 -1.0 3093749 BCB01_000313 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P16 compound treatment 17569.0 -264.0 -0.24 -0.2387 -1.0 3093750 BCB01_000314 OCC(O)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P17 compound treatment 18199.0 366.0 0.33 0.3302 1.0 3000147 BCB01_000315 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(I)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P18 compound treatment 16494.6 -1340.0 -1.21 -1.2089 -1.0 3093751 BCB01_000316 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P19 compound treatment 16564.3 -1270.0 -1.15 -1.146 -1.0 3093752 BCB01_000317 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P20 compound treatment 16079.1 -1750.0 -1.58 -1.5841 -1.0 3000149 BCB01_000318 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P21 compound treatment 17504.7 -329.0 -0.3 -0.2968 -1.0 3093752 BCB01_000319 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P22 compound treatment 18124.7 291.0 0.26 0.2631 1.0 3093753 BCB01_000320 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P23 mock treatment 17619.7 -214.0 -0.19 -0.1929 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2000 P24 mock treatment 17592.5 -241.0 -0.22 -0.2175 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A01 compound treatment 16686.6 -1480.0 -1.33 -1.3321 -1.0 3000745 BCB02_000001 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A02 compound treatment 18193.0 31.2 0.03 0.0282 1.0 3000746 BCB02_000002 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A03 compound treatment 17725.1 -437.0 -0.39 -0.3943 -1.0 3000747 BCB02_000003 OC(C1CCCCC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A04 compound treatment 18052.8 -109.0 -0.1 -0.0984 -1.0 3000748 BCB02_000004 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A05 compound treatment 18455.2 293.0 0.26 0.2649 1.0 3000749 BCB02_000005 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A06 compound treatment 18713.2 551.0 0.5 0.4979 1.0 3000750 BCB02_000006 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A07 compound treatment 18179.9 18.1 0.02 0.0163 1.0 3093754 BCB02_000007 CCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A08 compound treatment 17411.0 -751.0 -0.68 -0.678 -1.0 2065163 BCB02_000008 CCOC(=O)/C=C/c1ccccc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A09 compound treatment 18124.1 -37.7 -0.03 -0.034 -1.0 3093755 BCB02_000009 CCCCCCCCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A10 compound treatment 16908.4 -1250.0 -1.13 -1.1318 -1.0 3000752 BCB02_000010 CCOC(=O)/C=C/c1cc(F)ccc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A11 compound treatment 16745.7 -1420.0 -1.28 -1.2788 -1.0 3093756 BCB02_000011 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A12 compound treatment 16544.4 -1620.0 -1.46 -1.4605 -1.0 3000753 BCB02_000012 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A13 compound treatment 17092.5 -1070.0 -0.97 -0.9656 -1.0 3093757 BCB02_000013 COc1ccc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A14 compound treatment 16510.8 -1650.0 -1.49 -1.4909 -1.0 3000754 BCB02_000014 CCOC(=O)/C=C/c1cccc(OC)c1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A15 compound treatment 18495.0 333.0 0.3 0.3009 1.0 3093824 BCB02_000015 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A16 compound treatment 18168.2 6.4 0.01 0.0058 1.0 3000755 BCB02_000016 CCOC(=O)/C=C/c1cccc(C)c1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A17 mock treatment 18702.3 540.0 0.49 0.4881 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A18 mock treatment 18144.4 -17.4 -0.02 -0.0157 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A19 mock treatment 18576.5 415.0 0.37 0.3745 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A20 mock treatment 18457.1 295.0 0.27 0.2667 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A21 mock treatment 18120.2 -41.6 -0.04 -0.0376 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A22 mock treatment 18274.9 113.0 0.1 0.1021 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A23 mock treatment 18089.2 -72.6 -0.07 -0.0656 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 A24 mock treatment 15526.8 -2640.0 -2.38 -2.3794 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B01 compound treatment 17650.2 -512.0 -0.46 -0.462 -1.0 3093825 BCB02_000017 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B02 compound treatment 17611.1 -551.0 -0.5 -0.4973 -1.0 3000756 BCB02_000018 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B03 compound treatment 18311.5 150.0 0.14 0.1352 1.0 3093826 BCB02_000019 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B04 compound treatment 18401.1 239.0 0.22 0.2161 1.0 3000757 BCB02_000020 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B05 compound treatment 17592.8 -569.0 -0.51 -0.5138 -1.0 3093827 BCB02_000021 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(s5)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B06 compound treatment 18713.2 551.0 0.5 0.4979 1.0 3093828 BCB02_000022 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B07 compound treatment 17459.7 -702.0 -0.63 -0.634 -1.0 3000758 BCB02_000023 CC(C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B08 compound treatment 17055.2 -1110.0 -1.0 -0.9993 -1.0 3093829 BCB02_000024 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B09 compound treatment 17931.8 -230.0 -0.21 -0.2077 -1.0 3000759 BCB02_000025 CC(CC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(C)o5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B10 compound treatment 17436.1 -726.0 -0.66 -0.6553 -1.0 3093830 BCB02_000026 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B11 compound treatment 17639.0 -523.0 -0.47 -0.4721 -1.0 3093831 BCB02_000027 OC(Cc1ccccc1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B12 compound treatment 17249.2 -913.0 -0.82 -0.8241 -1.0 3000760 BCB02_000028 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B13 compound treatment 17966.2 -196.0 -0.18 -0.1766 -1.0 3093832 BCB02_000029 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B14 compound treatment 17664.6 -497.0 -0.45 -0.449 -1.0 3093833 BCB02_000030 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B15 compound treatment 18187.8 26.0 0.02 0.0235 1.0 3000761 BCB02_000031 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B16 compound treatment 17933.6 -228.0 -0.21 -0.2061 -1.0 3093834 BCB02_000032 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B17 mock treatment 18354.4 193.0 0.17 0.1739 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B18 mock treatment 18161.6 -0.205 0.0 -2.0E-4 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B19 mock treatment 18035.4 -126.0 -0.11 -0.1141 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B20 mock treatment 17940.5 -221.0 -0.2 -0.1998 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B21 mock treatment 18125.7 -36.1 -0.03 -0.0326 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B22 mock treatment 17861.2 -301.0 -0.27 -0.2714 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B23 mock treatment 17657.3 -505.0 -0.46 -0.4556 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 B24 mock treatment 16845.6 -1320.0 -1.19 -1.1885 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C01 compound treatment 18331.3 169.0 0.15 0.1531 1.0 3093835 BCB02_000033 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C02 compound treatment 18377.6 216.0 0.19 0.1949 1.0 3000762 BCB02_000034 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C03 compound treatment 17558.8 -603.0 -0.54 -0.5445 -1.0 3000763 BCB02_000035 Cc1ccccc1C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C04 compound treatment 18237.7 75.9 0.07 0.0685 1.0 3093836 BCB02_000036 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C05 compound treatment 17808.0 -354.0 -0.32 -0.3195 -1.0 3093837 BCB02_000037 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C06 compound treatment 18478.9 317.0 0.29 0.2863 1.0 3000764 BCB02_000038 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C07 compound treatment 17717.0 -445.0 -0.4 -0.4017 -1.0 3093838 BCB02_000039 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C08 compound treatment 17018.5 -1140.0 -1.03 -1.0324 -1.0 3000765 BCB02_000040 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C09 compound treatment 18100.9 -60.9 -0.05 -0.055 -1.0 3093839 BCB02_000041 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cccc6ccccc56 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C10 compound treatment 17497.8 -664.0 -0.6 -0.5996 -1.0 3000766 BCB02_000042 O=c1oc2ccccc2cc1C#C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C11 compound treatment 17494.6 -667.0 -0.6 -0.6025 -1.0 3093840 BCB02_000043 OC(C1CCC=CC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C12 compound treatment 17594.5 -567.0 -0.51 -0.5123 -1.0 3000767 BCB02_000044 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C13 compound treatment 18426.3 264.0 0.24 0.2388 1.0 3093841 BCB02_000045 CC(=O)n1cc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C14 compound treatment 16561.8 -1600.0 -1.44 -1.4448 -1.0 3000768 BCB02_000046 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C15 compound treatment 17659.6 -502.0 -0.45 -0.4535 -1.0 3093842 BCB02_000047 CCCCC(CC)C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C16 compound treatment 17965.9 -196.0 -0.18 -0.1769 -1.0 3093843 BCB02_000048 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C17 mock treatment 19266.2 1100.0 1.0 0.9973 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C18 mock treatment 18203.0 41.2 0.04 0.0372 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C19 mock treatment 19231.0 1070.0 0.97 0.9655 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C20 mock treatment 18367.8 206.0 0.19 0.186 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C21 mock treatment 18746.4 585.0 0.53 0.5279 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C22 mock treatment 18321.8 160.0 0.14 0.1445 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C23 mock treatment 18105.2 -56.6 -0.05 -0.0511 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 C24 mock treatment 18005.9 -156.0 -0.14 -0.1408 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D01 compound treatment 18717.0 555.0 0.5 0.5013 1.0 3000769 BCB02_000049 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D02 compound treatment 18594.9 433.0 0.39 0.3911 1.0 3093844 BCB02_000050 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D03 compound treatment 19372.3 1210.0 1.09 1.0931 1.0 3093845 BCB02_000051 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D04 compound treatment 18474.9 313.0 0.28 0.2827 1.0 3000770 BCB02_000052 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D05 compound treatment 18821.8 660.0 0.6 0.596 1.0 3093846 BCB02_000053 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c(C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D06 compound treatment 18747.7 586.0 0.53 0.5291 1.0 3000771 BCB02_000054 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D07 compound treatment 17481.4 -680.0 -0.61 -0.6144 -1.0 3092586 BCB02_000055 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D08 compound treatment 17837.1 -325.0 -0.29 -0.2932 -1.0 3092495 BCB02_000056 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D09 compound treatment 18050.4 -111.0 -0.1 -0.1006 -1.0 3000772 BCB02_000057 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D10 compound treatment 17482.3 -680.0 -0.61 -0.6136 -1.0 3092496 BCB02_000058 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D11 compound treatment 17919.6 -242.0 -0.22 -0.2187 -1.0 3092497 BCB02_000059 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D12 compound treatment 18476.5 315.0 0.28 0.2842 1.0 3000773 BCB02_000060 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D13 compound treatment 17737.3 -425.0 -0.38 -0.3833 -1.0 3092498 BCB02_000061 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D14 compound treatment 17204.0 -958.0 -0.86 -0.8649 -1.0 3000774 BCB02_000062 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D15 compound treatment 17964.9 -197.0 -0.18 -0.1778 -1.0 3092499 BCB02_000063 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)/C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D16 compound treatment 17958.3 -204.0 -0.18 -0.1838 -1.0 3000775 BCB02_000064 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D17 mock treatment 18620.7 459.0 0.41 0.4144 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D18 mock treatment 17503.3 -659.0 -0.59 -0.5946 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D19 mock treatment 17769.7 -392.0 -0.35 -0.3541 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D20 mock treatment 18632.2 470.0 0.42 0.4248 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D21 mock treatment 18525.4 364.0 0.33 0.3283 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D22 mock treatment 18289.3 127.0 0.12 0.1151 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D23 mock treatment 18216.5 54.7 0.05 0.0494 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 D24 mock treatment 17942.1 -220.0 -0.2 -0.1984 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E01 compound treatment 18377.6 216.0 0.19 0.1949 1.0 3092500 BCB02_000065 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E02 compound treatment 18135.5 -26.3 -0.02 -0.0238 -1.0 3000776 BCB02_000066 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E03 compound treatment 18034.0 -128.0 -0.12 -0.1154 -1.0 3000847 BCB02_000067 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E04 compound treatment 18878.3 716.0 0.65 0.647 1.0 3000848 BCB02_000068 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E05 compound treatment 17477.7 -684.0 -0.62 -0.6178 -1.0 3000849 BCB02_000069 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(Br)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E06 compound treatment 17445.5 -716.0 -0.65 -0.6468 -1.0 3000850 BCB02_000070 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E07 compound treatment 16873.3 -1290.0 -1.16 -1.1635 -1.0 3000851 BCB02_000071 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E08 compound treatment 17982.4 -179.0 -0.16 -0.162 -1.0 3092501 BCB02_000072 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E09 compound treatment 17594.5 -567.0 -0.51 -0.5123 -1.0 3000852 BCB02_000073 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E10 compound treatment 16784.4 -1380.0 -1.24 -1.2438 -1.0 3092502 BCB02_000074 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E11 compound treatment 17768.7 -393.0 -0.35 -0.355 -1.0 3092503 BCB02_000075 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E12 compound treatment 17332.6 -829.0 -0.75 -0.7488 -1.0 3000853 BCB02_000076 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E13 compound treatment 17524.4 -637.0 -0.58 -0.5756 -1.0 3092504 BCB02_000077 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E14 compound treatment 17549.5 -612.0 -0.55 -0.5529 -1.0 3000854 BCB02_000078 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E15 compound treatment 18483.1 321.0 0.29 0.2901 1.0 3092505 BCB02_000079 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E16 compound treatment 15966.8 -2200.0 -1.98 -1.9821 -1.0 3000855 BCB02_000080 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E17 mock treatment 18234.1 72.3 0.07 0.0653 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E18 mock treatment 18253.1 91.3 0.08 0.0824 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E19 mock treatment 19199.9 1040.0 0.94 0.9374 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E20 mock treatment 18731.6 570.0 0.51 0.5145 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E21 mock treatment 18912.9 751.0 0.68 0.6782 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E22 mock treatment 17903.0 -259.0 -0.23 -0.2337 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E23 mock treatment 18162.6 0.795 0.0 7.0E-4 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 E24 mock treatment 17467.9 -694.0 -0.63 -0.6266 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F01 compound treatment 18759.8 598.0 0.54 0.54 1.0 3092506 BCB02_000081 OC(COCc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F02 compound treatment 18718.8 557.0 0.5 0.503 1.0 3092507 BCB02_000082 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F03 compound treatment 18948.8 787.0 0.71 0.7107 1.0 3000856 BCB02_000083 COc1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F04 compound treatment 19503.1 1340.0 1.21 1.2112 1.0 3092508 BCB02_000084 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F05 compound treatment 18958.0 796.0 0.72 0.719 1.0 3092509 BCB02_000085 CCCCC(O)C1C=CC2C(N1Nc3ccc(OC)cc3)C(=O)N(C4CCCCC4)C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F06 compound treatment 17359.0 -803.0 -0.72 -0.7249 -1.0 3000857 BCB02_000086 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F07 compound treatment 18221.5 59.7 0.05 0.0539 1.0 3092510 BCB02_000087 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F08 compound treatment 17460.4 -701.0 -0.63 -0.6334 -1.0 3000858 BCB02_000088 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F09 compound treatment 17824.2 -338.0 -0.3 -0.3049 -1.0 3092511 BCB02_000089 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F10 compound treatment 18010.9 -151.0 -0.14 -0.1363 -1.0 3000859 BCB02_000090 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F11 compound treatment 17814.5 -347.0 -0.31 -0.3136 -1.0 3092512 BCB02_000091 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F12 compound treatment 18083.3 -78.5 -0.07 -0.0709 -1.0 3092513 BCB02_000092 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F13 compound treatment 17257.4 -904.0 -0.82 -0.8167 -1.0 3000860 BCB02_000093 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F14 compound treatment 18738.4 577.0 0.52 0.5207 1.0 3092514 BCB02_000094 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F15 compound treatment 17633.1 -529.0 -0.48 -0.4774 -1.0 3092515 BCB02_000095 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F16 compound treatment 18285.4 124.0 0.11 0.1116 1.0 3000861 BCB02_000096 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F17 mock treatment 18522.2 360.0 0.33 0.3254 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F18 mock treatment 18528.4 367.0 0.33 0.331 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F19 mock treatment 18565.4 404.0 0.36 0.3644 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F20 mock treatment 18699.5 538.0 0.49 0.4855 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F21 mock treatment 19525.1 1360.0 1.23 1.2311 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F22 mock treatment 18925.7 764.0 0.69 0.6898 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F23 mock treatment 18032.9 -129.0 -0.12 -0.1164 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 F24 mock treatment 18142.9 -18.9 -0.02 -0.0171 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G01 compound treatment 18276.9 115.0 0.1 0.1039 1.0 3092516 BCB02_000097 CC(C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G02 compound treatment 18286.0 124.0 0.11 0.1121 1.0 3000862 BCB02_000098 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G03 compound treatment 17670.7 -491.0 -0.44 -0.4435 -1.0 3092587 BCB02_000099 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G04 compound treatment 18711.5 550.0 0.5 0.4964 1.0 3000863 BCB02_000100 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G05 compound treatment 18885.5 724.0 0.65 0.6535 1.0 3092588 BCB02_000101 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G06 compound treatment 17448.0 -714.0 -0.64 -0.6446 -1.0 3092589 BCB02_000102 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G07 compound treatment 17714.7 -447.0 -0.4 -0.4037 -1.0 3000864 BCB02_000103 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G08 compound treatment 18030.6 -131.0 -0.12 -0.1185 -1.0 3092590 BCB02_000104 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G09 compound treatment 16314.5 -1850.0 -1.67 -1.6681 -1.0 3092591 BCB02_000105 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G10 compound treatment 17316.3 -846.0 -0.76 -0.7635 -1.0 3000865 BCB02_000106 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G11 compound treatment 17925.7 -236.0 -0.21 -0.2132 -1.0 3092592 BCB02_000107 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccn5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G12 compound treatment 18312.3 150.0 0.14 0.1359 1.0 3000866 BCB02_000108 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G13 compound treatment 17661.6 -500.0 -0.45 -0.4517 -1.0 3092593 BCB02_000109 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G14 compound treatment 17254.0 -908.0 -0.82 -0.8198 -1.0 3000867 BCB02_000110 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G15 compound treatment 17795.6 -366.0 -0.33 -0.3307 -1.0 3092594 BCB02_000111 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G16 compound treatment 17311.1 -851.0 -0.77 -0.7682 -1.0 3092595 BCB02_000112 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G17 mock treatment 18396.2 234.0 0.21 0.2117 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G18 mock treatment 18294.9 133.0 0.12 0.1202 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G19 mock treatment 19089.0 927.0 0.84 0.8373 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G20 mock treatment 18310.2 148.0 0.13 0.134 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G21 mock treatment 17713.0 -449.0 -0.41 -0.4053 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G22 mock treatment 17447.2 -715.0 -0.65 -0.6453 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G23 mock treatment 19093.5 932.0 0.84 0.8413 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 G24 mock treatment 18386.6 225.0 0.2 0.203 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H01 compound treatment 18262.4 101.0 0.09 0.0908 1.0 3000868 BCB02_000113 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)/C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H02 compound treatment 18690.7 529.0 0.48 0.4776 1.0 3092596 BCB02_000114 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H03 compound treatment 18935.7 774.0 0.7 0.6988 1.0 3092597 BCB02_000115 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H04 compound treatment 19234.9 1070.0 0.97 0.969 1.0 3000869 BCB02_000116 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H05 compound treatment 17341.8 -820.0 -0.74 -0.7405 -1.0 3092598 BCB02_000117 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H06 compound treatment 18760.2 598.0 0.54 0.5404 1.0 3000870 BCB02_000118 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H07 compound treatment 18254.6 92.8 0.08 0.0838 1.0 3000871 BCB02_000119 O=c1cccc(o1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H08 compound treatment 18545.5 384.0 0.35 0.3465 1.0 3092599 BCB02_000120 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H09 compound treatment 17974.5 -187.0 -0.17 -0.1691 -1.0 3000872 BCB02_000121 COc1cccc(c1)c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H10 compound treatment 18188.7 26.9 0.02 0.0243 1.0 3092600 BCB02_000122 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H11 compound treatment 17936.9 -225.0 -0.2 -0.2031 -1.0 1984103 BCB02_000123 Cc1ccc(cc1)c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H12 compound treatment 18067.3 -94.5 -0.09 -0.0853 -1.0 3092601 BCB02_000124 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H13 compound treatment 17706.1 -456.0 -0.41 -0.4115 -1.0 3000873 BCB02_000125 Clc1cccc(c1)c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H14 compound treatment 17915.5 -246.0 -0.22 -0.2224 -1.0 3000874 BCB02_000126 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H15 compound treatment 17874.3 -288.0 -0.26 -0.2596 -1.0 3000875 BCB02_000127 Clc1ccccc1c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H16 compound treatment 18356.4 195.0 0.18 0.1757 1.0 3092602 BCB02_000128 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H17 mock treatment 18173.4 11.6 0.01 0.0105 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H18 mock treatment 18267.8 106.0 0.1 0.0957 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H19 mock treatment 18804.2 642.0 0.58 0.5801 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H20 mock treatment 18050.7 -111.0 -0.1 -0.1003 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H21 mock treatment 18979.1 817.0 0.74 0.738 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H22 mock treatment 18648.6 487.0 0.44 0.4396 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H23 mock treatment 17074.1 -1090.0 -0.98 -0.9822 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 H24 mock treatment 17876.1 -286.0 -0.26 -0.258 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I01 compound treatment 17830.6 -331.0 -0.3 -0.2991 -1.0 3092603 BCB02_000129 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccs5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I02 compound treatment 18818.5 657.0 0.59 0.593 1.0 3000947 BCB02_000130 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(F)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I03 compound treatment 18210.9 49.1 0.04 0.0443 1.0 3000948 BCB02_000131 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I04 compound treatment 18724.8 563.0 0.51 0.5084 1.0 3000949 BCB02_000132 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I05 compound treatment 19055.0 893.0 0.81 0.8066 1.0 3000950 BCB02_000133 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I06 compound treatment 18659.4 498.0 0.45 0.4493 1.0 3000951 BCB02_000134 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I07 compound treatment 17084.7 -1080.0 -0.97 -0.9726 -1.0 3092604 BCB02_000135 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I08 compound treatment 18018.7 -143.0 -0.13 -0.1292 -1.0 3000952 BCB02_000136 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I09 compound treatment 16433.1 -1730.0 -1.56 -1.561 -1.0 3092605 BCB02_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I10 compound treatment 17059.1 -1100.0 -1.0 -0.9958 -1.0 3092606 BCB02_000138 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I11 compound treatment 17714.3 -448.0 -0.4 -0.4041 -1.0 3000953 BCB02_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I12 compound treatment 17242.1 -920.0 -0.83 -0.8305 -1.0 3092607 BCB02_000140 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I13 compound treatment 17805.4 -356.0 -0.32 -0.3218 -1.0 3092678 BCB02_000141 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I14 compound treatment 17608.4 -553.0 -0.5 -0.4997 -1.0 3000954 BCB02_000142 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I15 compound treatment 17919.6 -242.0 -0.22 -0.2187 -1.0 3092679 BCB02_000143 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I16 compound treatment 17513.0 -649.0 -0.59 -0.5859 -1.0 3000955 BCB02_000144 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I17 mock treatment 17856.4 -305.0 -0.28 -0.2758 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I18 mock treatment 18360.3 198.0 0.18 0.1792 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I19 mock treatment 18203.3 41.5 0.04 0.0375 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I20 mock treatment 18640.8 479.0 0.43 0.4325 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I21 mock treatment 18324.9 163.0 0.15 0.1473 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I22 mock treatment 18412.4 251.0 0.23 0.2263 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I23 mock treatment 18242.7 80.9 0.07 0.073 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 I24 mock treatment 17955.1 -207.0 -0.19 -0.1867 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J01 compound treatment 18769.6 608.0 0.55 0.5488 1.0 3000956 BCB02_000145 CCCc1cccc(=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J02 compound treatment 19168.6 1010.0 0.91 0.9091 1.0 3092680 BCB02_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J03 compound treatment 18832.7 671.0 0.61 0.6058 1.0 3000957 BCB02_000147 Fc1ccc(cc1)c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J04 compound treatment 19647.8 1490.0 1.34 1.3419 1.0 3092681 BCB02_000148 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J05 compound treatment 18908.4 747.0 0.67 0.6742 1.0 3000958 BCB02_000149 O=c1cccc(o1)c2ccc(C#N)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J06 compound treatment 17042.4 -1120.0 -1.01 -1.0108 -1.0 3000959 BCB02_000150 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J07 compound treatment 18379.8 218.0 0.2 0.1969 1.0 3092682 BCB02_000151 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J08 compound treatment 18444.1 282.0 0.25 0.2549 1.0 3092683 BCB02_000152 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J09 compound treatment 16319.5 -1840.0 -1.66 -1.6636 -1.0 3000960 BCB02_000153 FC(F)(F)c1ccccc1c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J10 compound treatment 18413.0 251.0 0.23 0.2268 1.0 3092684 BCB02_000154 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J11 compound treatment 17511.6 -650.0 -0.59 -0.5871 -1.0 3000961 BCB02_000155 O=c1cccc(o1)c2ccc3ccccc3c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J12 compound treatment 18150.1 -11.7 -0.01 -0.0106 -1.0 3000962 BCB02_000156 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J13 compound treatment 18044.9 -117.0 -0.11 -0.1056 -1.0 3092685 BCB02_000157 O=c1cccc(o1)c2ccco2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J14 compound treatment 16765.1 -1400.0 -1.26 -1.2612 -1.0 3092686 BCB02_000158 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J15 compound treatment 18336.5 175.0 0.16 0.1578 1.0 3000963 BCB02_000159 O=c1cccc(CCc2ccccc2)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J16 compound treatment 18005.3 -157.0 -0.14 -0.1413 -1.0 3092687 BCB02_000160 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J17 mock treatment 18434.7 273.0 0.25 0.2464 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J18 mock treatment 17988.6 -173.0 -0.16 -0.1564 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J19 mock treatment 16835.5 -1330.0 -1.2 -1.1977 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J20 mock treatment 18843.7 682.0 0.62 0.6158 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J21 mock treatment 19036.6 875.0 0.79 0.7899 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J22 mock treatment 17279.0 -883.0 -0.8 -0.7972 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J23 mock treatment 17763.2 -399.0 -0.36 -0.3599 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 J24 mock treatment 17642.8 -519.0 -0.47 -0.4687 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K01 compound treatment 18079.5 -82.3 -0.07 -0.0743 -1.0 3000964 BCB02_000161 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K02 compound treatment 18277.2 115.0 0.1 0.1042 1.0 3092688 BCB02_000162 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K03 compound treatment 18276.8 115.0 0.1 0.1038 1.0 3092689 BCB02_000163 CC(C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K04 compound treatment 18216.4 54.6 0.05 0.0493 1.0 3000965 BCB02_000164 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K05 compound treatment 18790.8 629.0 0.57 0.568 1.0 3092690 BCB02_000165 CC(CC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K06 compound treatment 18575.1 413.0 0.37 0.3732 1.0 3000966 BCB02_000166 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K07 compound treatment 17299.0 -863.0 -0.78 -0.7791 -1.0 3092691 BCB02_000167 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccs5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K08 compound treatment 17419.6 -742.0 -0.67 -0.6702 -1.0 3092692 BCB02_000168 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K09 compound treatment 17562.2 -600.0 -0.54 -0.5414 -1.0 3000967 BCB02_000169 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K10 compound treatment 17518.2 -644.0 -0.58 -0.5812 -1.0 3092693 BCB02_000170 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K11 compound treatment 16793.6 -1370.0 -1.24 -1.2355 -1.0 3000968 BCB02_000171 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K12 compound treatment 17590.1 -572.0 -0.52 -0.5163 -1.0 3092694 BCB02_000172 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K13 compound treatment 17247.9 -914.0 -0.83 -0.8253 -1.0 3092695 BCB02_000173 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K14 compound treatment 17351.1 -811.0 -0.73 -0.7321 -1.0 3000969 BCB02_000174 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K15 compound treatment 17873.0 -289.0 -0.26 -0.2608 -1.0 3092696 BCB02_000175 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K16 compound treatment 17891.6 -270.0 -0.24 -0.244 -1.0 3000970 BCB02_000176 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)N(CC)CC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K17 mock treatment 18253.8 92.0 0.08 0.0831 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K18 mock treatment 18653.6 492.0 0.44 0.4441 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K19 mock treatment 18138.6 -23.2 -0.02 -0.021 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K20 mock treatment 18355.6 194.0 0.17 0.175 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K21 mock treatment 18801.0 639.0 0.58 0.5772 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K22 mock treatment 17449.2 -713.0 -0.64 -0.6435 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K23 mock treatment 18082.4 -79.4 -0.07 -0.0717 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 K24 mock treatment 16726.7 -1440.0 -1.3 -1.2959 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L01 compound treatment 17937.8 -224.0 -0.2 -0.2023 -1.0 3000971 BCB02_000177 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L02 compound treatment 17829.5 -332.0 -0.3 -0.3001 -1.0 3092697 BCB02_000178 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L03 compound treatment 18113.4 -48.4 -0.04 -0.0437 -1.0 3000972 BCB02_000179 O=c1cccc(/C=C/c2ccccc2)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L04 compound treatment 18341.0 179.0 0.16 0.1618 1.0 3092698 BCB02_000180 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L05 compound treatment 16983.6 -1180.0 -1.06 -1.0639 -1.0 3000973 BCB02_000181 O=c1cccc(o1)c2cccc3ccccc23 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L06 compound treatment 16567.7 -1590.0 -1.44 -1.4395 -1.0 3092699 BCB02_000182 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L07 compound treatment 18156.7 -5.1 0.0 -0.0046 -1.0 3000974 BCB02_000183 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L08 compound treatment 18202.4 40.6 0.04 0.0367 1.0 3092700 BCB02_000184 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L09 compound treatment 17671.4 -490.0 -0.44 -0.4428 -1.0 3092701 BCB02_000185 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L10 compound treatment 18031.2 -131.0 -0.12 -0.1179 -1.0 3000975 BCB02_000186 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L11 compound treatment 18305.0 143.0 0.13 0.1293 1.0 3092771 BCB02_000187 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L12 compound treatment 18238.9 77.1 0.07 0.0696 1.0 3000976 BCB02_000188 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L13 compound treatment 16621.3 -1540.0 -1.39 -1.3911 -1.0 3092772 BCB02_000189 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L14 compound treatment 18154.2 -7.6 -0.01 -0.0069 -1.0 3092773 BCB02_000190 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L15 compound treatment 18404.6 243.0 0.22 0.2192 1.0 3000977 BCB02_000191 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L16 compound treatment 17752.7 -409.0 -0.37 -0.3694 -1.0 3092774 BCB02_000192 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L17 mock treatment 18222.6 60.8 0.05 0.0549 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L18 mock treatment 17747.5 -414.0 -0.37 -0.3741 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L19 mock treatment 18396.8 235.0 0.21 0.2122 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L20 mock treatment 17807.6 -354.0 -0.32 -0.3198 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L21 mock treatment 18414.7 253.0 0.23 0.2284 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L22 mock treatment 18503.3 341.0 0.31 0.3084 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L23 mock treatment 19125.9 964.0 0.87 0.8706 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 L24 mock treatment 17041.0 -1120.0 -1.01 -1.0121 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M01 compound treatment 18991.1 829.0 0.75 0.7489 1.0 3000978 BCB02_000193 CC1(C)[C@H]2C[C@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M02 compound treatment 17059.8 -1100.0 -1.0 -0.9951 -1.0 3001047 BCB02_000194 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M03 compound treatment 17629.0 -533.0 -0.48 -0.4811 -1.0 3092775 BCB02_000195 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M04 compound treatment 17829.3 -333.0 -0.3 -0.3003 -1.0 3001048 BCB02_000196 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M05 compound treatment 17795.5 -366.0 -0.33 -0.3308 -1.0 3092776 BCB02_000197 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)[N+](=O)[O-])C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M06 compound treatment 18321.1 159.0 0.14 0.1438 1.0 3001049 BCB02_000198 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M07 compound treatment 16908.1 -1250.0 -1.13 -1.1321 -1.0 3092777 BCB02_000199 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M08 compound treatment 17490.6 -671.0 -0.61 -0.6061 -1.0 3092778 BCB02_000200 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M09 compound treatment 17235.5 -926.0 -0.84 -0.8365 -1.0 3001050 BCB02_000201 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M10 compound treatment 17568.9 -593.0 -0.54 -0.5354 -1.0 3001168 BCB02_000202 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M11 compound treatment 17743.2 -419.0 -0.38 -0.378 -1.0 3092779 BCB02_000203 COc1ccc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M12 compound treatment 17485.1 -677.0 -0.61 -0.6111 -1.0 3092780 BCB02_000204 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M13 compound treatment 17726.4 -435.0 -0.39 -0.3932 -1.0 3001169 BCB02_000205 COc1ccc(NN2C3C(C=CC2C(O)C4=CC[C@H](CC4)C(=C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M14 compound treatment 18112.1 -49.7 -0.04 -0.0449 -1.0 3092781 BCB02_000206 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M15 compound treatment 17603.3 -559.0 -0.5 -0.5043 -1.0 3001170 BCB02_000207 COc1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M16 mock treatment 18049.3 -113.0 -0.1 -0.1016 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M17 mock treatment 18402.5 241.0 0.22 0.2173 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M18 mock treatment 17388.5 -773.0 -0.7 -0.6983 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M19 mock treatment 19058.1 896.0 0.81 0.8094 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M20 mock treatment 18155.9 -5.9 -0.01 -0.0053 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M21 mock treatment 17570.3 -592.0 -0.53 -0.5341 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M22 mock treatment 18081.5 -80.3 -0.07 -0.0725 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M23 mock treatment 17517.3 -645.0 -0.58 -0.582 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 M24 mock treatment 17422.3 -740.0 -0.67 -0.6678 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N01 compound treatment 18170.1 8.3 0.01 0.0075 1.0 3092782 BCB02_000208 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N02 compound treatment 19236.8 1070.0 0.97 0.9707 1.0 3092783 BCB02_000209 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N03 compound treatment 17400.9 -761.0 -0.69 -0.6871 -1.0 3001171 BCB02_000210 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N04 compound treatment 17822.0 -340.0 -0.31 -0.3068 -1.0 3092784 BCB02_000211 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N05 compound treatment 18016.0 -146.0 -0.13 -0.1317 -1.0 3001172 BCB02_000212 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N06 compound treatment 18606.8 445.0 0.4 0.4018 1.0 3092785 BCB02_000213 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N07 compound treatment 17216.6 -945.0 -0.85 -0.8535 -1.0 3092786 BCB02_000214 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N08 compound treatment 18191.4 29.6 0.03 0.0267 1.0 3001173 BCB02_000215 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N09 compound treatment 17651.9 -510.0 -0.46 -0.4604 -1.0 3092787 BCB02_000216 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N10 compound treatment 19271.5 1110.0 1.0 1.0021 1.0 3001174 BCB02_000217 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N11 compound treatment 17503.4 -658.0 -0.59 -0.5945 -1.0 3092788 BCB02_000218 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N12 compound treatment 18118.2 -43.6 -0.04 -0.0394 -1.0 3092789 BCB02_000219 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N13 compound treatment 18129.0 -32.8 -0.03 -0.0296 -1.0 3001175 BCB02_000220 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N14 compound treatment 17869.8 -292.0 -0.26 -0.2637 -1.0 3092790 BCB02_000221 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N15 compound treatment 17677.0 -485.0 -0.44 -0.4378 -1.0 3001176 BCB02_000222 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N16 mock treatment 19176.1 1010.0 0.92 0.9159 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N17 mock treatment 17603.9 -558.0 -0.5 -0.5038 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N18 mock treatment 18946.8 785.0 0.71 0.7089 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N19 mock treatment 18031.9 -130.0 -0.12 -0.1173 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N20 mock treatment 18602.2 440.0 0.4 0.3977 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N21 mock treatment 18776.7 615.0 0.56 0.5553 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N22 mock treatment 18311.5 150.0 0.14 0.1352 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N23 mock treatment 18061.7 -100.0 -0.09 -0.0904 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 N24 mock treatment 19355.4 1190.0 1.08 1.0778 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O01 compound treatment 17154.7 -1010.0 -0.91 -0.9094 -1.0 3092791 BCB02_000223 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O02 compound treatment 17118.9 -1040.0 -0.94 -0.9418 -1.0 3001177 BCB02_000224 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O03 compound treatment 17173.6 -988.0 -0.89 -0.8924 -1.0 3092792 BCB02_000225 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)c(OCc5ccccc5)c4)C(=O)N(C6CCCCC6)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O04 compound treatment 15398.0 -2760.0 -2.5 -2.4957 -1.0 3001178 BCB02_000226 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O05 compound treatment 17621.5 -540.0 -0.49 -0.4879 -1.0 3092860 BCB02_000227 COc1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O06 compound treatment 18171.6 9.8 0.01 0.0088 1.0 3001179 BCB02_000228 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O07 compound treatment 17261.9 -900.0 -0.81 -0.8126 -1.0 3092861 BCB02_000229 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O08 compound treatment 16852.7 -1310.0 -1.18 -1.1821 -1.0 3001245 BCB02_000230 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O09 compound treatment 15940.4 -2220.0 -2.01 -2.0059 -1.0 3092862 BCB02_000231 COc1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O10 compound treatment 16808.7 -1350.0 -1.22 -1.2219 -1.0 3001246 BCB02_000232 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O11 compound treatment 17752.9 -409.0 -0.37 -0.3692 -1.0 3092863 BCB02_000233 Cc1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C5CCCCC5)C3=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O12 compound treatment 17994.1 -168.0 -0.15 -0.1514 -1.0 3001247 BCB02_000234 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O13 compound treatment 18218.4 56.6 0.05 0.0511 1.0 3092864 BCB02_000235 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O14 compound treatment 17588.4 -573.0 -0.52 -0.5178 -1.0 3001248 BCB02_000236 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O15 compound treatment 17967.9 -194.0 -0.18 -0.1751 -1.0 3092865 BCB02_000237 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O16 mock treatment 17582.5 -579.0 -0.52 -0.5231 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O17 mock treatment 17834.2 -328.0 -0.3 -0.2958 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O18 mock treatment 16988.0 -1170.0 -1.06 -1.06 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O19 mock treatment 18677.7 516.0 0.47 0.4659 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O20 mock treatment 17902.2 -260.0 -0.23 -0.2344 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O21 mock treatment 18085.8 -76.0 -0.07 -0.0686 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O22 mock treatment 16846.4 -1320.0 -1.19 -1.1878 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O23 mock treatment 17317.8 -844.0 -0.76 -0.7621 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 O24 mock treatment 16085.9 -2080.0 -1.87 -1.8746 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P01 compound treatment 17830.4 -331.0 -0.3 -0.2993 -1.0 3001249 BCB02_000238 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P02 compound treatment 16688.7 -1470.0 -1.33 -1.3302 -1.0 3092866 BCB02_000239 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P03 compound treatment 17834.6 -327.0 -0.3 -0.2955 -1.0 3001250 BCB02_000240 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P04 compound treatment 17498.7 -663.0 -0.6 -0.5988 -1.0 3092867 BCB02_000241 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P05 compound treatment 16568.0 -1590.0 -1.44 -1.4392 -1.0 3001251 BCB02_000242 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P06 compound treatment 16203.0 -1960.0 -1.77 -1.7688 -1.0 3092868 BCB02_000243 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P07 compound treatment 16763.9 -1400.0 -1.26 -1.2623 -1.0 3001252 BCB02_000244 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P08 compound treatment 17860.2 -302.0 -0.27 -0.2724 -1.0 3092869 BCB02_000245 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P09 compound treatment 16858.0 -1300.0 -1.18 -1.1773 -1.0 3001253 BCB02_000246 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P10 compound treatment 17784.4 -377.0 -0.34 -0.3408 -1.0 3092870 BCB02_000247 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P11 compound treatment 17630.4 -531.0 -0.48 -0.4799 -1.0 3001254 BCB02_000248 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P12 compound treatment 18488.8 327.0 0.3 0.2953 1.0 3092871 BCB02_000249 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P13 compound treatment 18403.9 242.0 0.22 0.2186 1.0 3001255 BCB02_000250 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P14 compound treatment 17371.1 -791.0 -0.71 -0.714 -1.0 3092774 BCB02_000251 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P15 compound treatment 18400.4 239.0 0.22 0.2155 1.0 3092872 BCB02_000252 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P16 mock treatment 16950.1 -1210.0 -1.09 -1.0942 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P17 mock treatment 17755.4 -406.0 -0.37 -0.367 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P18 mock treatment 17225.7 -936.0 -0.85 -0.8453 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P19 mock treatment 18458.3 296.0 0.27 0.2677 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P20 mock treatment 17947.8 -214.0 -0.19 -0.1932 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P21 mock treatment 18269.3 107.0 0.1 0.0971 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P22 mock treatment 17315.0 -847.0 -0.76 -0.7647 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P23 mock treatment 17614.8 -547.0 -0.49 -0.4939 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2088 P24 mock treatment 16706.8 -1460.0 -1.31 -1.3139 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A01 compound treatment 13485.8 -845.0 -0.76 -0.7634 -1.0 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A02 compound treatment 14041.2 -290.0 -0.26 -0.2619 -1.0 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A03 compound treatment 14451.6 120.0 0.11 0.1087 1.0 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A04 compound treatment 14449.4 118.0 0.11 0.1067 1.0 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A05 compound treatment 13589.7 -742.0 -0.67 -0.6696 -1.0 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A06 compound treatment 14175.7 -156.0 -0.14 -0.1405 -1.0 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A07 compound treatment 13835.5 -496.0 -0.45 -0.4477 -1.0 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A08 compound treatment 14179.5 -152.0 -0.14 -0.137 -1.0 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A09 compound treatment 14019.4 -312.0 -0.28 -0.2816 -1.0 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A10 compound treatment 13824.6 -507.0 -0.46 -0.4575 -1.0 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A11 compound treatment 14050.2 -281.0 -0.25 -0.2538 -1.0 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A12 compound treatment 13833.9 -497.0 -0.45 -0.4491 -1.0 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A13 mock treatment 13704.0 -627.0 -0.57 -0.5664 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A14 mock treatment 14690.9 360.0 0.32 0.3248 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A15 compound treatment 13959.5 -372.0 -0.34 -0.3357 -1.0 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A16 compound treatment 13662.3 -669.0 -0.6 -0.6041 -1.0 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A17 compound treatment 15618.9 1290.0 1.16 1.1628 1.0 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A18 compound treatment 13592.3 -739.0 -0.67 -0.6673 -1.0 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A19 compound treatment 14824.9 494.0 0.45 0.4458 1.0 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A20 compound treatment 13840.5 -491.0 -0.44 -0.4431 -1.0 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A21 compound treatment 14334.7 3.45 0.0 0.0031 1.0 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A22 compound treatment 14180.0 -151.0 -0.14 -0.1366 -1.0 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A23 compound treatment 14517.4 186.0 0.17 0.1681 1.0 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 A24 compound treatment 13858.2 -473.0 -0.43 -0.4272 -1.0 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B01 compound treatment 13602.6 -729.0 -0.66 -0.658 -1.0 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B02 compound treatment 14242.9 -88.3 -0.08 -0.0798 -1.0 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B03 compound treatment 14508.7 177.0 0.16 0.1602 1.0 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B04 compound treatment 14466.5 135.0 0.12 0.1221 1.0 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B05 compound treatment 14436.2 105.0 0.09 0.0948 1.0 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B06 compound treatment 14219.6 -112.0 -0.1 -0.1008 -1.0 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B07 compound treatment 14544.7 213.0 0.19 0.1928 1.0 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B08 compound treatment 14082.6 -249.0 -0.22 -0.2245 -1.0 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B09 compound treatment 14396.6 65.4 0.06 0.059 1.0 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B10 compound treatment 14579.8 249.0 0.22 0.2244 1.0 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B11 compound treatment 13928.5 -403.0 -0.36 -0.3637 -1.0 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B12 compound treatment 14321.6 -9.65 -0.01 -0.0087 -1.0 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B13 mock treatment 14315.0 -16.2 -0.01 -0.0147 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B14 mock treatment 14463.9 133.0 0.12 0.1198 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B15 compound treatment 14415.0 83.8 0.08 0.0756 1.0 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B16 compound treatment 14099.8 -231.0 -0.21 -0.209 -1.0 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B17 compound treatment 13632.3 -699.0 -0.63 -0.6312 -1.0 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B18 compound treatment 14356.8 25.6 0.02 0.0231 1.0 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B19 compound treatment 14645.5 314.0 0.28 0.2838 1.0 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B20 compound treatment 14486.7 155.0 0.14 0.1404 1.0 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B21 compound treatment 14978.9 648.0 0.58 0.5848 1.0 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B22 compound treatment 14169.0 -162.0 -0.15 -0.1465 -1.0 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B23 compound treatment 14783.7 452.0 0.41 0.4086 1.0 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 B24 compound treatment 14610.5 279.0 0.25 0.2522 1.0 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C01 compound treatment 13453.0 -878.0 -0.79 -0.7931 -1.0 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C02 compound treatment 14407.5 76.3 0.07 0.0689 1.0 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C03 compound treatment 14072.2 -259.0 -0.23 -0.2339 -1.0 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C04 compound treatment 13940.3 -391.0 -0.35 -0.353 -1.0 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C05 compound treatment 14307.3 -23.9 -0.02 -0.0216 -1.0 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C06 compound treatment 14297.4 -33.8 -0.03 -0.0306 -1.0 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C07 compound treatment 14372.4 41.2 0.04 0.0372 1.0 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C08 compound treatment 14722.9 392.0 0.35 0.3537 1.0 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C09 compound treatment 14590.9 260.0 0.23 0.2345 1.0 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C10 compound treatment 13995.4 -336.0 -0.3 -0.3033 -1.0 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C11 mock treatment 14199.2 -132.0 -0.12 -0.1192 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C12 mock treatment 14643.0 312.0 0.28 0.2815 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C13 compound treatment 13529.4 -802.0 -0.72 -0.7241 -1.0 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C14 compound treatment 14222.2 -109.0 -0.1 -0.0985 -1.0 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C15 mock treatment 14645.2 314.0 0.28 0.2835 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C16 mock treatment 15047.4 716.0 0.65 0.6467 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C17 compound treatment 14084.2 -247.0 -0.22 -0.2231 -1.0 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C18 compound treatment 14351.3 20.1 0.02 0.0181 1.0 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C19 compound treatment 14227.2 -104.0 -0.09 -0.094 -1.0 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C20 compound treatment 14670.2 339.0 0.31 0.3061 1.0 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C21 compound treatment 14435.2 104.0 0.09 0.0939 1.0 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C22 compound treatment 14010.0 -321.0 -0.29 -0.2901 -1.0 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C23 compound treatment 14623.4 292.0 0.26 0.2638 1.0 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 C24 compound treatment 13160.4 -1170.0 -1.06 -1.0573 -1.0 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D01 compound treatment 14315.2 -16.0 -0.01 -0.0145 -1.0 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D02 compound treatment 14499.8 169.0 0.15 0.1522 1.0 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D03 compound treatment 14421.6 90.4 0.08 0.0816 1.0 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D04 compound treatment 14401.1 69.9 0.06 0.0631 1.0 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D05 compound treatment 14265.7 -65.5 -0.06 -0.0592 -1.0 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D06 compound treatment 14448.1 117.0 0.11 0.1055 1.0 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D07 compound treatment 13901.8 -429.0 -0.39 -0.3878 -1.0 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D08 compound treatment 14438.5 107.0 0.1 0.0969 1.0 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D09 compound treatment 14940.8 610.0 0.55 0.5504 1.0 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D10 compound treatment 14776.7 445.0 0.4 0.4022 1.0 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D11 mock treatment 13772.6 -559.0 -0.5 -0.5045 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D12 mock treatment 14899.6 568.0 0.51 0.5132 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D13 compound treatment 14078.1 -253.0 -0.23 -0.2286 -1.0 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D14 compound treatment 14494.8 164.0 0.15 0.1477 1.0 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D15 mock treatment 14772.1 441.0 0.4 0.3981 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D16 mock treatment 14613.7 282.0 0.26 0.2551 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D17 compound treatment 14386.0 54.8 0.05 0.0494 1.0 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D18 compound treatment 14069.5 -262.0 -0.24 -0.2364 -1.0 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D19 compound treatment 14576.5 245.0 0.22 0.2215 1.0 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D20 compound treatment 14038.3 -293.0 -0.26 -0.2645 -1.0 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D21 compound treatment 13728.1 -603.0 -0.54 -0.5446 -1.0 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D22 compound treatment 14060.8 -270.0 -0.24 -0.2442 -1.0 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D23 compound treatment 14482.5 151.0 0.14 0.1366 1.0 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 D24 compound treatment 13606.2 -725.0 -0.65 -0.6547 -1.0 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E01 mock treatment 14157.4 -174.0 -0.16 -0.157 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E02 mock treatment 14441.2 110.0 0.1 0.0993 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E03 compound treatment 14694.9 364.0 0.33 0.3284 1.0 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E04 compound treatment 14525.9 195.0 0.18 0.1758 1.0 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E05 compound treatment 14530.7 199.0 0.18 0.1801 1.0 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E06 compound treatment 13715.7 -616.0 -0.56 -0.5558 -1.0 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E07 compound treatment 13847.3 -484.0 -0.44 -0.437 -1.0 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E08 compound treatment 14471.6 140.0 0.13 0.1267 1.0 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E09 mock treatment 14392.0 60.8 0.05 0.0549 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E10 mock treatment 14673.3 342.0 0.31 0.3089 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E11 compound treatment 14481.2 150.0 0.14 0.1354 1.0 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E12 compound treatment 14197.6 -134.0 -0.12 -0.1207 -1.0 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E13 compound treatment 13836.5 -495.0 -0.45 -0.4468 -1.0 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E14 compound treatment 14291.3 -39.9 -0.04 -0.0361 -1.0 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E15 compound treatment 14396.1 64.9 0.06 0.0586 1.0 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E16 compound treatment 14128.9 -202.0 -0.18 -0.1827 -1.0 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E17 mock treatment 14371.8 40.6 0.04 0.0366 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E18 mock treatment 14767.9 437.0 0.39 0.3943 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E19 compound treatment 14557.2 226.0 0.2 0.204 1.0 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E20 compound treatment 14211.3 -120.0 -0.11 -0.1083 -1.0 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E21 compound treatment 14517.7 186.0 0.17 0.1684 1.0 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E22 compound treatment 14370.2 39.0 0.04 0.0352 1.0 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E23 compound treatment 14468.6 137.0 0.12 0.124 1.0 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 E24 compound treatment 13359.5 -972.0 -0.88 -0.8775 -1.0 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F01 mock treatment 14531.2 200.0 0.18 0.1806 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F02 mock treatment 14458.6 127.0 0.12 0.115 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F03 compound treatment 14954.1 623.0 0.56 0.5624 1.0 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F04 compound treatment 15098.8 768.0 0.69 0.6931 1.0 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F05 compound treatment 14064.7 -267.0 -0.24 -0.2407 -1.0 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F06 compound treatment 14639.1 308.0 0.28 0.278 1.0 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F07 compound treatment 13716.0 -615.0 -0.56 -0.5556 -1.0 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F08 compound treatment 14324.9 -6.35 -0.01 -0.0057 -1.0 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F09 mock treatment 14895.3 564.0 0.51 0.5093 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F10 mock treatment 14750.3 419.0 0.38 0.3784 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F11 compound treatment 14257.4 -73.8 -0.07 -0.0667 -1.0 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F12 compound treatment 14313.2 -18.0 -0.02 -0.0163 -1.0 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F13 compound treatment 13324.0 -1010.0 -0.91 -0.9096 -1.0 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F14 compound treatment 14438.3 107.0 0.1 0.0967 1.0 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F15 compound treatment 13695.6 -636.0 -0.57 -0.574 -1.0 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F16 compound treatment 14807.1 476.0 0.43 0.4297 1.0 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F17 mock treatment 14409.8 78.6 0.07 0.0709 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F18 mock treatment 14511.3 180.0 0.16 0.1626 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F19 compound treatment 13744.8 -586.0 -0.53 -0.5296 -1.0 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F20 compound treatment 14754.2 423.0 0.38 0.3819 1.0 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F21 compound treatment 14935.1 604.0 0.55 0.5453 1.0 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F22 compound treatment 14419.4 88.2 0.08 0.0796 1.0 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F23 compound treatment 14454.4 123.0 0.11 0.1112 1.0 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 F24 compound treatment 13973.5 -358.0 -0.32 -0.323 -1.0 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G01 compound treatment 13997.8 -333.0 -0.3 -0.3011 -1.0 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G02 compound treatment 14476.3 145.0 0.13 0.131 1.0 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G03 mock treatment 14282.1 -49.1 -0.04 -0.0444 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G04 mock treatment 14788.7 457.0 0.41 0.4131 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G05 compound treatment 14496.7 165.0 0.15 0.1494 1.0 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G06 compound treatment 14384.1 52.9 0.05 0.0477 1.0 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G07 compound treatment 14398.2 67.0 0.06 0.0605 1.0 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G08 compound treatment 14461.0 130.0 0.12 0.1172 1.0 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G09 compound treatment 14235.9 -95.3 -0.09 -0.0861 -1.0 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G10 compound treatment 14576.3 245.0 0.22 0.2213 1.0 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G11 compound treatment 13980.7 -351.0 -0.32 -0.3165 -1.0 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G12 compound treatment 14810.7 479.0 0.43 0.433 1.0 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G13 compound treatment 13308.8 -1020.0 -0.92 -0.9233 -1.0 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G14 compound treatment 13997.7 -334.0 -0.3 -0.3012 -1.0 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G15 compound treatment 14769.0 438.0 0.4 0.3953 1.0 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G16 compound treatment 14575.8 245.0 0.22 0.2208 1.0 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G17 compound treatment 14670.6 339.0 0.31 0.3064 1.0 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G18 compound treatment 14286.4 -44.8 -0.04 -0.0405 -1.0 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G19 mock treatment 14975.6 644.0 0.58 0.5819 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G20 mock treatment 15001.3 670.0 0.61 0.6051 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G21 compound treatment 14397.7 66.5 0.06 0.06 1.0 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G22 compound treatment 14335.3 4.05 0.0 0.0037 1.0 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G23 compound treatment 14806.3 475.0 0.43 0.429 1.0 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 G24 compound treatment 13955.7 -376.0 -0.34 -0.3391 -1.0 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H01 compound treatment 13982.5 -349.0 -0.31 -0.3149 -1.0 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H02 compound treatment 14172.0 -159.0 -0.14 -0.1438 -1.0 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H03 mock treatment 14516.7 185.0 0.17 0.1675 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H04 mock treatment 14460.4 129.0 0.12 0.1166 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H05 compound treatment 13879.5 -452.0 -0.41 -0.4079 -1.0 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H06 compound treatment 14653.6 322.0 0.29 0.2911 1.0 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H07 compound treatment 14378.3 47.1 0.04 0.0425 1.0 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H08 compound treatment 14618.3 287.0 0.26 0.2592 1.0 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H09 compound treatment 14179.0 -152.0 -0.14 -0.1375 -1.0 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H10 compound treatment 14876.7 545.0 0.49 0.4925 1.0 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H11 compound treatment 14068.6 -263.0 -0.24 -0.2372 -1.0 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H12 compound treatment 14286.4 -44.8 -0.04 -0.0405 -1.0 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H13 compound treatment 13942.0 -389.0 -0.35 -0.3515 -1.0 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H14 compound treatment 14622.2 291.0 0.26 0.2627 1.0 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H15 compound treatment 14518.2 187.0 0.17 0.1688 1.0 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H16 compound treatment 14603.8 273.0 0.25 0.2461 1.0 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H17 compound treatment 15087.1 756.0 0.68 0.6825 1.0 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H18 compound treatment 14914.1 583.0 0.53 0.5263 1.0 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H19 mock treatment 14268.3 -62.9 -0.06 -0.0568 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H20 mock treatment 14262.5 -68.7 -0.06 -0.0621 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H21 compound treatment 14505.7 174.0 0.16 0.1575 1.0 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H22 compound treatment 14078.8 -252.0 -0.23 -0.228 -1.0 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H23 compound treatment 14012.5 -319.0 -0.29 -0.2878 -1.0 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 H24 compound treatment 12609.2 -1720.0 -1.56 -1.555 -1.0 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I01 compound treatment 14302.5 -28.7 -0.03 -0.026 -1.0 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I02 compound treatment 14609.7 278.0 0.25 0.2514 1.0 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I03 compound treatment 14253.6 -77.6 -0.07 -0.0701 -1.0 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I04 compound treatment 14704.8 374.0 0.34 0.3373 1.0 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I05 mock treatment 14120.7 -211.0 -0.19 -0.1901 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I06 mock treatment 14630.7 299.0 0.27 0.2704 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I07 compound treatment 13755.1 -576.0 -0.52 -0.5203 -1.0 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I08 compound treatment 14681.7 350.0 0.32 0.3165 1.0 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I09 compound treatment 14545.8 215.0 0.19 0.1937 1.0 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I10 compound treatment 14606.8 276.0 0.25 0.2488 1.0 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I11 compound treatment 13765.9 -565.0 -0.51 -0.5105 -1.0 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I12 compound treatment 14373.6 42.4 0.04 0.0382 1.0 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I13 compound treatment 13984.6 -347.0 -0.31 -0.313 -1.0 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I14 compound treatment 14224.8 -106.0 -0.1 -0.0961 -1.0 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I15 compound treatment 14454.8 124.0 0.11 0.1116 1.0 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I16 compound treatment 14851.4 520.0 0.47 0.4697 1.0 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I17 compound treatment 14195.9 -135.0 -0.12 -0.1222 -1.0 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I18 compound treatment 14554.2 223.0 0.2 0.2013 1.0 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I19 compound treatment 14348.3 17.1 0.02 0.0154 1.0 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I20 compound treatment 14566.6 235.0 0.21 0.2125 1.0 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I21 mock treatment 14965.1 634.0 0.57 0.5724 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I22 mock treatment 14212.0 -119.0 -0.11 -0.1077 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I23 compound treatment 14491.0 160.0 0.14 0.1443 1.0 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 I24 compound treatment 14087.1 -244.0 -0.22 -0.2205 -1.0 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J01 compound treatment 13732.6 -599.0 -0.54 -0.5406 -1.0 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J02 compound treatment 13331.1 -1000.0 -0.9 -0.9031 -1.0 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J03 compound treatment 13921.5 -410.0 -0.37 -0.37 -1.0 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J04 compound treatment 14386.4 55.2 0.05 0.0498 1.0 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J05 mock treatment 14837.5 506.0 0.46 0.4572 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J06 mock treatment 13742.7 -589.0 -0.53 -0.5315 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J07 compound treatment 14248.2 -83.0 -0.07 -0.075 -1.0 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J08 compound treatment 14902.1 571.0 0.52 0.5155 1.0 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J09 compound treatment 14084.2 -247.0 -0.22 -0.2231 -1.0 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J10 compound treatment 13950.4 -381.0 -0.34 -0.3439 -1.0 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J11 compound treatment 13658.9 -672.0 -0.61 -0.6071 -1.0 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J12 compound treatment 14445.4 114.0 0.1 0.1031 1.0 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J13 compound treatment 14163.6 -168.0 -0.15 -0.1514 -1.0 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J14 compound treatment 13637.2 -694.0 -0.63 -0.6267 -1.0 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J15 compound treatment 13478.5 -853.0 -0.77 -0.77 -1.0 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J16 compound treatment 14659.7 328.0 0.3 0.2966 1.0 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J17 compound treatment 14628.2 297.0 0.27 0.2682 1.0 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J18 compound treatment 13612.9 -718.0 -0.65 -0.6487 -1.0 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J19 compound treatment 15209.1 878.0 0.79 0.7927 1.0 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J20 compound treatment 14634.8 304.0 0.27 0.2741 1.0 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J21 mock treatment 14843.5 512.0 0.46 0.4626 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J22 mock treatment 14090.2 -241.0 -0.22 -0.2177 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J23 compound treatment 13947.5 -384.0 -0.35 -0.3465 -1.0 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 J24 compound treatment 14378.5 47.3 0.04 0.0427 1.0 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K01 compound treatment 14062.5 -269.0 -0.24 -0.2427 -1.0 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K02 compound treatment 14048.5 -283.0 -0.26 -0.2553 -1.0 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K03 compound treatment 14298.8 -32.4 -0.03 -0.0293 -1.0 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K04 compound treatment 14289.2 -42.0 -0.04 -0.038 -1.0 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K05 compound treatment 14334.0 2.75 0.0 0.0025 1.0 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K06 compound treatment 13578.9 -752.0 -0.68 -0.6794 -1.0 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K07 mock treatment 14226.5 -105.0 -0.09 -0.0946 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K08 mock treatment 14308.9 -22.3 -0.02 -0.0202 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K09 compound treatment 14180.7 -151.0 -0.14 -0.1359 -1.0 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K10 compound treatment 14123.7 -208.0 -0.19 -0.1874 -1.0 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K11 compound treatment 13512.2 -819.0 -0.74 -0.7396 -1.0 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K12 compound treatment 14504.8 174.0 0.16 0.1567 1.0 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K13 compound treatment 13681.3 -650.0 -0.59 -0.5869 -1.0 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K14 compound treatment 14510.0 179.0 0.16 0.1614 1.0 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K15 mock treatment 14771.9 441.0 0.4 0.3979 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K16 mock treatment 14787.1 456.0 0.41 0.4116 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K17 compound treatment 13982.2 -349.0 -0.32 -0.3152 -1.0 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K18 compound treatment 14305.9 -25.3 -0.02 -0.0229 -1.0 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K19 compound treatment 13730.1 -601.0 -0.54 -0.5428 -1.0 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K20 compound treatment 14357.9 26.7 0.02 0.0241 1.0 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K21 compound treatment 14744.6 413.0 0.37 0.3733 1.0 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K22 compound treatment 14557.8 227.0 0.2 0.2046 1.0 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K23 mock treatment 14072.3 -259.0 -0.23 -0.2338 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 K24 mock treatment 13995.5 -336.0 -0.3 -0.3032 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L01 compound treatment 14004.4 -327.0 -0.3 -0.2951 -1.0 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L02 compound treatment 13481.6 -850.0 -0.77 -0.7672 -1.0 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L03 compound treatment 13832.0 -499.0 -0.45 -0.4508 -1.0 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L04 compound treatment 14127.4 -204.0 -0.18 -0.1841 -1.0 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L05 compound treatment 13935.9 -395.0 -0.36 -0.357 -1.0 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L06 compound treatment 14414.2 83.0 0.07 0.0749 1.0 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L07 mock treatment 14700.4 369.0 0.33 0.3333 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L08 mock treatment 13505.7 -826.0 -0.75 -0.7455 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L09 compound treatment 14383.6 52.4 0.05 0.0473 1.0 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L10 compound treatment 14964.2 633.0 0.57 0.5716 1.0 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L11 compound treatment 14112.7 -219.0 -0.2 -0.1973 -1.0 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L12 compound treatment 13953.5 -378.0 -0.34 -0.3411 -1.0 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L13 compound treatment 14160.3 -171.0 -0.15 -0.1544 -1.0 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L14 compound treatment 13510.9 -820.0 -0.74 -0.7408 -1.0 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L15 mock treatment 14322.3 -8.95 -0.01 -0.0081 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L16 mock treatment 14125.0 -206.0 -0.19 -0.1862 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L17 compound treatment 14619.3 288.0 0.26 0.2601 1.0 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L18 compound treatment 14558.0 227.0 0.2 0.2048 1.0 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L19 compound treatment 13904.0 -427.0 -0.39 -0.3858 -1.0 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L20 compound treatment 14480.2 149.0 0.13 0.1345 1.0 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L21 compound treatment 12788.9 -1540.0 -1.39 -1.3927 -1.0 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L22 compound treatment 13515.8 -815.0 -0.74 -0.7364 -1.0 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L23 mock treatment 14129.6 -202.0 -0.18 -0.1821 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 L24 mock treatment 13968.6 -363.0 -0.33 -0.3275 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M01 compound treatment 13487.2 -844.0 -0.76 -0.7622 -1.0 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M02 compound treatment 13622.9 -708.0 -0.64 -0.6396 -1.0 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M03 compound treatment 14083.6 -248.0 -0.22 -0.2236 -1.0 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M04 compound treatment 13844.6 -487.0 -0.44 -0.4394 -1.0 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M05 compound treatment 14740.6 409.0 0.37 0.3697 1.0 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M06 compound treatment 14219.1 -112.0 -0.1 -0.1013 -1.0 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M07 compound treatment 13118.2 -1210.0 -1.1 -1.0954 -1.0 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M08 compound treatment 14294.5 -36.7 -0.03 -0.0332 -1.0 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M09 mock treatment 13889.0 -442.0 -0.4 -0.3994 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M10 mock treatment 14444.6 113.0 0.1 0.1024 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M11 compound treatment 14301.6 -29.6 -0.03 -0.0268 -1.0 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M12 compound treatment 13665.5 -666.0 -0.6 -0.6012 -1.0 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M13 mock treatment 14231.1 -100.0 -0.09 -0.0904 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M14 mock treatment 14159.8 -171.0 -0.15 -0.1548 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M15 compound treatment 14948.7 617.0 0.56 0.5576 1.0 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M16 compound treatment 14176.4 -155.0 -0.14 -0.1398 -1.0 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M17 compound treatment 14586.3 255.0 0.23 0.2303 1.0 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M18 compound treatment 14490.1 159.0 0.14 0.1434 1.0 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M19 compound treatment 14989.8 659.0 0.59 0.5947 1.0 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M20 compound treatment 14228.7 -103.0 -0.09 -0.0926 -1.0 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M21 compound treatment 14259.6 -71.6 -0.06 -0.0647 -1.0 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M22 compound treatment 14121.6 -210.0 -0.19 -0.1893 -1.0 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M23 compound treatment 12936.8 -1390.0 -1.26 -1.2592 -1.0 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 M24 compound treatment 14132.7 -199.0 -0.18 -0.1793 -1.0 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N01 compound treatment 13482.0 -849.0 -0.77 -0.7669 -1.0 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N02 compound treatment 13754.0 -577.0 -0.52 -0.5213 -1.0 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N03 compound treatment 13889.8 -441.0 -0.4 -0.3986 -1.0 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N04 compound treatment 15032.2 701.0 0.63 0.633 1.0 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N05 compound treatment 14305.1 -26.1 -0.02 -0.0236 -1.0 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N06 compound treatment 14582.3 251.0 0.23 0.2267 1.0 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N07 compound treatment 14381.0 49.8 0.04 0.0449 1.0 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N08 compound treatment 13818.8 -512.0 -0.46 -0.4627 -1.0 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N09 mock treatment 13944.8 -386.0 -0.35 -0.349 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N10 mock treatment 14351.4 20.2 0.02 0.0182 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N11 compound treatment 12900.5 -1430.0 -1.29 -1.292 -1.0 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N12 compound treatment 13646.6 -685.0 -0.62 -0.6182 -1.0 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N13 mock treatment 13237.3 -1090.0 -0.99 -0.9878 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N14 mock treatment 14116.4 -215.0 -0.19 -0.194 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N15 compound treatment 14055.9 -275.0 -0.25 -0.2486 -1.0 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N16 compound treatment 13917.7 -414.0 -0.37 -0.3734 -1.0 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N17 compound treatment 13820.5 -511.0 -0.46 -0.4612 -1.0 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N18 compound treatment 13943.8 -387.0 -0.35 -0.3499 -1.0 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N19 compound treatment 14100.8 -230.0 -0.21 -0.2081 -1.0 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N20 compound treatment 13741.5 -590.0 -0.53 -0.5325 -1.0 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N21 compound treatment 13870.1 -461.0 -0.42 -0.4164 -1.0 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N22 compound treatment 13894.2 -437.0 -0.39 -0.3947 -1.0 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N23 compound treatment 14282.3 -48.9 -0.04 -0.0442 -1.0 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 N24 compound treatment 13523.3 -808.0 -0.73 -0.7296 -1.0 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O01 compound treatment 12725.2 -1610.0 -1.45 -1.4503 -1.0 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O02 compound treatment 13100.5 -1230.0 -1.11 -1.1114 -1.0 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O03 compound treatment 13328.1 -1000.0 -0.91 -0.9058 -1.0 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O04 compound treatment 13611.4 -720.0 -0.65 -0.65 -1.0 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O05 compound treatment 14285.7 -45.5 -0.04 -0.0411 -1.0 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O06 compound treatment 14210.4 -121.0 -0.11 -0.1091 -1.0 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O07 compound treatment 13778.5 -553.0 -0.5 -0.4991 -1.0 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O08 compound treatment 13872.8 -458.0 -0.41 -0.414 -1.0 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O09 compound treatment 13517.4 -814.0 -0.73 -0.7349 -1.0 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O10 compound treatment 13634.5 -697.0 -0.63 -0.6292 -1.0 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O11 mock treatment 13347.0 -984.0 -0.89 -0.8888 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O12 mock treatment 13270.8 -1060.0 -0.96 -0.9576 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O13 compound treatment 13351.8 -979.0 -0.88 -0.8844 -1.0 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O14 compound treatment 13639.4 -692.0 -0.62 -0.6247 -1.0 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O15 compound treatment 13420.5 -911.0 -0.82 -0.8224 -1.0 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O16 compound treatment 13836.2 -495.0 -0.45 -0.447 -1.0 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O17 compound treatment 13472.6 -859.0 -0.78 -0.7754 -1.0 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O18 compound treatment 13866.4 -465.0 -0.42 -0.4198 -1.0 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O19 compound treatment 13665.8 -665.0 -0.6 -0.6009 -1.0 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O20 compound treatment 13535.9 -795.0 -0.72 -0.7182 -1.0 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O21 compound treatment 14035.8 -295.0 -0.27 -0.2668 -1.0 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O22 compound treatment 13468.3 -863.0 -0.78 -0.7792 -1.0 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O23 compound treatment 14033.3 -298.0 -0.27 -0.269 -1.0 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 O24 compound treatment 13817.8 -513.0 -0.46 -0.4636 -1.0 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P01 compound treatment 12129.5 -2200.0 -1.99 -1.9882 -1.0 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P02 compound treatment 12053.9 -2280.0 -2.06 -2.0565 -1.0 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P03 compound treatment 13511.2 -820.0 -0.74 -0.7405 -1.0 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P04 compound treatment 12615.3 -1720.0 -1.55 -1.5495 -1.0 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P05 compound treatment 13379.2 -952.0 -0.86 -0.8597 -1.0 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P06 compound treatment 11932.4 -2400.0 -2.17 -2.1662 -1.0 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P07 compound treatment 13890.7 -441.0 -0.4 -0.3978 -1.0 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P08 compound treatment 13736.4 -595.0 -0.54 -0.5371 -1.0 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P09 compound treatment 13545.6 -786.0 -0.71 -0.7094 -1.0 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P10 compound treatment 13951.1 -380.0 -0.34 -0.3433 -1.0 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P11 mock treatment 13774.4 -557.0 -0.5 -0.5028 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P12 mock treatment 13394.6 -937.0 -0.85 -0.8458 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P13 compound treatment 13417.8 -913.0 -0.82 -0.8248 -1.0 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P14 compound treatment 13460.0 -871.0 -0.79 -0.7867 -1.0 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P15 compound treatment 14091.5 -240.0 -0.22 -0.2165 -1.0 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P16 compound treatment 13751.0 -580.0 -0.52 -0.524 -1.0 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P17 compound treatment 14195.9 -135.0 -0.12 -0.1222 -1.0 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P18 compound treatment 13534.0 -797.0 -0.72 -0.7199 -1.0 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P19 compound treatment 13248.5 -1080.0 -0.98 -0.9777 -1.0 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P20 compound treatment 13316.0 -1020.0 -0.92 -0.9168 -1.0 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P21 compound treatment 13577.0 -754.0 -0.68 -0.6811 -1.0 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P22 compound treatment 13268.8 -1060.0 -0.96 -0.9594 -1.0 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P23 compound treatment 13090.0 -1240.0 -1.12 -1.1209 -1.0 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2093 P24 compound treatment 12904.7 -1430.0 -1.29 -1.2882 -1.0 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A01 compound treatment 13461.4 -872.0 -0.79 -0.7872 -1.0 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A02 compound treatment 6966.49 -7370.0 -6.65 -6.6521 -1.0 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A03 compound treatment 13630.0 -703.0 -0.63 -0.6349 -1.0 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A04 compound treatment 13642.0 -691.0 -0.62 -0.6241 -1.0 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A05 compound treatment 14953.2 620.0 0.56 0.5599 1.0 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A06 compound treatment 14038.9 -294.0 -0.27 -0.2657 -1.0 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A07 compound treatment 14791.7 459.0 0.41 0.4141 1.0 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A08 compound treatment 13576.4 -757.0 -0.68 -0.6833 -1.0 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A09 compound treatment 14401.0 67.9 0.06 0.0613 1.0 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A10 compound treatment 13499.3 -834.0 -0.75 -0.7529 -1.0 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A11 compound treatment 13110.7 -1220.0 -1.1 -1.1038 -1.0 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A12 compound treatment 13226.3 -1110.0 -1.0 -0.9995 -1.0 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A13 mock treatment 13998.4 -335.0 -0.3 -0.3022 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A14 mock treatment 13584.4 -749.0 -0.68 -0.6761 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A15 compound treatment 14057.5 -276.0 -0.25 -0.2489 -1.0 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A16 compound treatment 13828.6 -505.0 -0.46 -0.4556 -1.0 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A17 compound treatment 14579.0 246.0 0.22 0.222 1.0 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A18 compound treatment 13623.3 -710.0 -0.64 -0.641 -1.0 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A19 compound treatment 15006.5 673.0 0.61 0.6081 1.0 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A20 compound treatment 14591.3 258.0 0.23 0.2331 1.0 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A21 compound treatment 13775.1 -558.0 -0.5 -0.5039 -1.0 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A22 compound treatment 13352.1 -981.0 -0.89 -0.8859 -1.0 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A23 compound treatment 13402.4 -931.0 -0.84 -0.8404 -1.0 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 A24 compound treatment 12544.7 -1790.0 -1.61 -1.615 -1.0 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B01 compound treatment 13316.3 -1020.0 -0.92 -0.9182 -1.0 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B02 compound treatment 14898.6 565.0 0.51 0.5106 1.0 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B03 compound treatment 15246.2 913.0 0.82 0.8245 1.0 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B04 compound treatment 14228.0 -105.0 -0.09 -0.0949 -1.0 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B05 compound treatment 14744.3 411.0 0.37 0.3713 1.0 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B06 compound treatment 14511.0 178.0 0.16 0.1606 1.0 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B07 compound treatment 14398.8 65.7 0.06 0.0593 1.0 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B08 compound treatment 13857.7 -475.0 -0.43 -0.4293 -1.0 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B09 compound treatment 13897.2 -436.0 -0.39 -0.3936 -1.0 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B10 compound treatment 13416.8 -916.0 -0.83 -0.8274 -1.0 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B11 compound treatment 13679.3 -654.0 -0.59 -0.5904 -1.0 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B12 compound treatment 13559.4 -774.0 -0.7 -0.6987 -1.0 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B13 mock treatment 14291.7 -41.4 -0.04 -0.0374 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B14 mock treatment 14151.1 -182.0 -0.16 -0.1644 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B15 compound treatment 14252.7 -80.4 -0.07 -0.0726 -1.0 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B16 compound treatment 13762.3 -571.0 -0.52 -0.5154 -1.0 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B17 compound treatment 14276.0 -57.1 -0.05 -0.0516 -1.0 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B18 compound treatment 13846.7 -486.0 -0.44 -0.4392 -1.0 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B19 compound treatment 13978.0 -355.0 -0.32 -0.3207 -1.0 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B20 compound treatment 14166.5 -167.0 -0.15 -0.1505 -1.0 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B21 compound treatment 14185.9 -147.0 -0.13 -0.1329 -1.0 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B22 compound treatment 13993.3 -340.0 -0.31 -0.3069 -1.0 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B23 compound treatment 14356.0 22.9 0.02 0.0207 1.0 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 B24 compound treatment 13262.2 -1070.0 -0.97 -0.967 -1.0 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C01 compound treatment 14064.0 -269.0 -0.24 -0.243 -1.0 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C02 compound treatment 14630.4 297.0 0.27 0.2685 1.0 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C03 compound treatment 14585.4 252.0 0.23 0.2278 1.0 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C04 compound treatment 14288.3 -44.8 -0.04 -0.0405 -1.0 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C05 compound treatment 14649.1 316.0 0.29 0.2853 1.0 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C06 compound treatment 14264.4 -68.7 -0.06 -0.062 -1.0 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C07 compound treatment 13985.0 -348.0 -0.31 -0.3143 -1.0 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C08 compound treatment 13741.5 -592.0 -0.53 -0.5342 -1.0 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C09 compound treatment 14194.0 -139.0 -0.13 -0.1256 -1.0 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C10 compound treatment 13754.2 -579.0 -0.52 -0.5228 -1.0 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C11 mock treatment 14392.1 59.0 0.05 0.0533 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C12 mock treatment 13861.3 -472.0 -0.43 -0.4261 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C13 compound treatment 14299.7 -33.4 -0.03 -0.0302 -1.0 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C14 compound treatment 13888.1 -445.0 -0.4 -0.4019 -1.0 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C15 mock treatment 14013.4 -320.0 -0.29 -0.2887 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C16 mock treatment 13716.4 -617.0 -0.56 -0.5569 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C17 compound treatment 14694.9 362.0 0.33 0.3267 1.0 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C18 compound treatment 14128.5 -205.0 -0.18 -0.1848 -1.0 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C19 compound treatment 15119.8 787.0 0.71 0.7104 1.0 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C20 compound treatment 13289.7 -1040.0 -0.94 -0.9422 -1.0 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C21 compound treatment 14351.3 18.2 0.02 0.0164 1.0 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C22 compound treatment 14390.7 57.6 0.05 0.052 1.0 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C23 compound treatment 14232.2 -101.0 -0.09 -0.0911 -1.0 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 C24 compound treatment 13668.9 -664.0 -0.6 -0.5998 -1.0 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D01 compound treatment 14044.2 -289.0 -0.26 -0.2609 -1.0 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D02 compound treatment 14515.8 183.0 0.16 0.165 1.0 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D03 compound treatment 14622.1 289.0 0.26 0.261 1.0 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D04 compound treatment 14380.4 47.3 0.04 0.0427 1.0 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D05 compound treatment 14948.0 615.0 0.56 0.5552 1.0 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D06 compound treatment 14797.0 464.0 0.42 0.4189 1.0 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D07 compound treatment 13987.2 -346.0 -0.31 -0.3124 -1.0 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D08 compound treatment 14225.1 -108.0 -0.1 -0.0975 -1.0 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D09 compound treatment 14073.5 -260.0 -0.23 -0.2344 -1.0 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D10 compound treatment 13714.2 -619.0 -0.56 -0.5589 -1.0 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D11 mock treatment 13904.7 -428.0 -0.39 -0.3869 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D12 mock treatment 14567.1 234.0 0.21 0.2113 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D13 compound treatment 14000.6 -333.0 -0.3 -0.3003 -1.0 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D14 compound treatment 14085.1 -248.0 -0.22 -0.224 -1.0 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D15 mock treatment 14922.6 589.0 0.53 0.5323 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D16 mock treatment 14086.7 -246.0 -0.22 -0.2225 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D17 compound treatment 14945.9 613.0 0.55 0.5534 1.0 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D18 compound treatment 14604.7 272.0 0.25 0.2452 1.0 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D19 compound treatment 14677.5 344.0 0.31 0.311 1.0 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D20 compound treatment 14031.6 -302.0 -0.27 -0.2723 -1.0 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D21 compound treatment 14945.0 612.0 0.55 0.5525 1.0 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D22 compound treatment 14164.3 -169.0 -0.15 -0.1524 -1.0 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D23 compound treatment 14018.5 -315.0 -0.28 -0.2841 -1.0 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 D24 compound treatment 13454.7 -878.0 -0.79 -0.7932 -1.0 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E01 mock treatment 14261.3 -71.8 -0.06 -0.0648 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E02 mock treatment 14539.4 206.0 0.19 0.1863 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E03 compound treatment 14984.0 651.0 0.59 0.5878 1.0 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E04 compound treatment 13946.7 -386.0 -0.35 -0.3489 -1.0 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E05 compound treatment 14816.8 484.0 0.44 0.4368 1.0 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E06 compound treatment 14300.3 -32.8 -0.03 -0.0296 -1.0 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E07 compound treatment 14307.6 -25.5 -0.02 -0.023 -1.0 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E08 compound treatment 14230.3 -103.0 -0.09 -0.0928 -1.0 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E09 mock treatment 13387.2 -946.0 -0.85 -0.8542 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E10 mock treatment 13736.9 -596.0 -0.54 -0.5384 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E11 compound treatment 13505.9 -827.0 -0.75 -0.747 -1.0 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E12 compound treatment 13720.9 -612.0 -0.55 -0.5528 -1.0 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E13 compound treatment 13929.0 -404.0 -0.36 -0.3649 -1.0 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E14 compound treatment 13735.1 -598.0 -0.54 -0.54 -1.0 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E15 compound treatment 14414.7 81.6 0.07 0.0737 1.0 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E16 compound treatment 14087.2 -246.0 -0.22 -0.2221 -1.0 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E17 mock treatment 14525.5 192.0 0.17 0.1737 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E18 mock treatment 13888.0 -445.0 -0.4 -0.4019 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E19 compound treatment 15037.6 704.0 0.64 0.6362 1.0 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E20 compound treatment 13041.2 -1290.0 -1.17 -1.1666 -1.0 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E21 compound treatment 14773.3 440.0 0.4 0.3975 1.0 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E22 compound treatment 12650.0 -1680.0 -1.52 -1.5199 -1.0 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E23 compound treatment 14066.5 -267.0 -0.24 -0.2408 -1.0 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 E24 compound treatment 13920.0 -413.0 -0.37 -0.373 -1.0 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F01 mock treatment 14623.8 291.0 0.26 0.2625 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F02 mock treatment 14423.9 90.8 0.08 0.082 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F03 compound treatment 14610.4 277.0 0.25 0.2504 1.0 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F04 compound treatment 15019.3 686.0 0.62 0.6196 1.0 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F05 compound treatment 14824.4 491.0 0.44 0.4436 1.0 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F06 compound treatment 12826.9 -1510.0 -1.36 -1.3601 -1.0 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F07 compound treatment 15071.5 738.0 0.67 0.6668 1.0 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F08 compound treatment 14565.4 232.0 0.21 0.2098 1.0 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F09 mock treatment 14291.4 -41.7 -0.04 -0.0377 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F10 mock treatment 15269.7 937.0 0.85 0.8457 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F11 compound treatment 14084.9 -248.0 -0.22 -0.2241 -1.0 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F12 compound treatment 14511.6 178.0 0.16 0.1612 1.0 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F13 compound treatment 14356.6 23.5 0.02 0.0212 1.0 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F14 compound treatment 15201.5 868.0 0.78 0.7842 1.0 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F15 compound treatment 15214.4 881.0 0.8 0.7958 1.0 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F16 compound treatment 15001.5 668.0 0.6 0.6036 1.0 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F17 mock treatment 14672.6 339.0 0.31 0.3066 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F18 mock treatment 15058.8 726.0 0.66 0.6553 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F19 compound treatment 15255.4 922.0 0.83 0.8328 1.0 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F20 compound treatment 14825.3 492.0 0.44 0.4444 1.0 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F21 compound treatment 14635.4 302.0 0.27 0.273 1.0 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F22 compound treatment 15017.3 684.0 0.62 0.6178 1.0 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F23 compound treatment 14358.4 25.3 0.02 0.0228 1.0 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 F24 compound treatment 14790.7 458.0 0.41 0.4132 1.0 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G01 compound treatment 13958.5 -375.0 -0.34 -0.3383 -1.0 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G02 compound treatment 14669.9 337.0 0.3 0.3041 1.0 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G03 mock treatment 15039.5 706.0 0.64 0.6379 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G04 mock treatment 15063.5 730.0 0.66 0.6595 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G05 compound treatment 15232.4 899.0 0.81 0.8121 1.0 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G06 compound treatment 14925.2 592.0 0.53 0.5347 1.0 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G07 compound treatment 14092.5 -241.0 -0.22 -0.2173 -1.0 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G08 compound treatment 14588.9 256.0 0.23 0.231 1.0 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G09 compound treatment 13997.4 -336.0 -0.3 -0.3032 -1.0 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G10 compound treatment 14422.9 89.8 0.08 0.0811 1.0 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G11 compound treatment 14326.3 -6.81 -0.01 -0.0062 -1.0 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G12 compound treatment 14225.3 -108.0 -0.1 -0.0974 -1.0 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G13 compound treatment 14070.5 -263.0 -0.24 -0.2371 -1.0 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G14 compound treatment 14584.9 252.0 0.23 0.2274 1.0 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G15 compound treatment 14089.0 -244.0 -0.22 -0.2204 -1.0 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G16 compound treatment 14440.6 107.0 0.1 0.0971 1.0 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G17 compound treatment 14450.3 117.0 0.11 0.1058 1.0 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G18 compound treatment 15463.0 1130.0 1.02 1.0203 1.0 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G19 mock treatment 14704.8 372.0 0.34 0.3356 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G20 mock treatment 14907.6 574.0 0.52 0.5188 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G21 compound treatment 14833.1 500.0 0.45 0.4515 1.0 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G22 compound treatment 15916.8 1580.0 1.43 1.4301 1.0 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G23 compound treatment 14717.6 384.0 0.35 0.3472 1.0 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 G24 compound treatment 14517.4 184.0 0.17 0.1664 1.0 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H01 compound treatment 14588.5 255.0 0.23 0.2306 1.0 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H02 compound treatment 14889.2 556.0 0.5 0.5021 1.0 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H03 mock treatment 15104.8 772.0 0.7 0.6968 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H04 mock treatment 15194.3 861.0 0.78 0.7777 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H05 compound treatment 14975.2 642.0 0.58 0.5798 1.0 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H06 compound treatment 15028.4 695.0 0.63 0.6278 1.0 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H07 compound treatment 13376.7 -956.0 -0.86 -0.8636 -1.0 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H08 compound treatment 14729.2 396.0 0.36 0.3577 1.0 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H09 compound treatment 13933.5 -400.0 -0.36 -0.3609 -1.0 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H10 compound treatment 14652.5 319.0 0.29 0.2884 1.0 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H11 compound treatment 14481.9 149.0 0.13 0.1344 1.0 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H12 compound treatment 15029.7 697.0 0.63 0.629 1.0 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H13 compound treatment 14244.8 -88.3 -0.08 -0.0797 -1.0 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H14 compound treatment 14763.7 431.0 0.39 0.3888 1.0 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H15 compound treatment 14427.7 94.6 0.09 0.0854 1.0 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H16 compound treatment 14483.2 150.0 0.14 0.1355 1.0 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H17 compound treatment 14509.0 176.0 0.16 0.1588 1.0 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H18 compound treatment 15317.3 984.0 0.89 0.8887 1.0 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H19 mock treatment 14892.6 559.0 0.51 0.5052 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H20 mock treatment 14753.4 420.0 0.38 0.3795 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H21 compound treatment 14735.6 402.0 0.36 0.3634 1.0 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H22 compound treatment 14886.1 553.0 0.5 0.4994 1.0 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H23 compound treatment 15195.0 862.0 0.78 0.7783 1.0 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 H24 compound treatment 14467.3 134.0 0.12 0.1212 1.0 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I01 compound treatment 13534.6 -799.0 -0.72 -0.7211 -1.0 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I02 compound treatment 14360.2 27.1 0.02 0.0245 1.0 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I03 compound treatment 14904.2 571.0 0.52 0.5157 1.0 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I04 compound treatment 15325.3 992.0 0.9 0.896 1.0 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I05 mock treatment 15467.7 1130.0 1.02 1.0245 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I06 mock treatment 14828.3 495.0 0.45 0.4472 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I07 compound treatment 14719.9 387.0 0.35 0.3493 1.0 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I08 compound treatment 14597.0 264.0 0.24 0.2383 1.0 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I09 compound treatment 14014.5 -319.0 -0.29 -0.2877 -1.0 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I10 compound treatment 14750.8 418.0 0.38 0.3772 1.0 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I11 compound treatment 14038.4 -295.0 -0.27 -0.2661 -1.0 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I12 compound treatment 14015.8 -317.0 -0.29 -0.2865 -1.0 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I13 compound treatment 14076.2 -257.0 -0.23 -0.232 -1.0 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I14 compound treatment 14310.1 -23.0 -0.02 -0.0208 -1.0 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I15 compound treatment 14406.8 73.7 0.07 0.0665 1.0 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I16 compound treatment 14514.5 181.0 0.16 0.1638 1.0 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I17 compound treatment 14170.6 -163.0 -0.15 -0.1468 -1.0 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I18 compound treatment 14318.2 -14.9 -0.01 -0.0135 -1.0 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I19 compound treatment 14640.0 307.0 0.28 0.2771 1.0 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I20 compound treatment 14605.3 272.0 0.25 0.2458 1.0 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I21 mock treatment 14786.2 453.0 0.41 0.4091 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I22 mock treatment 14617.8 285.0 0.26 0.2571 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I23 compound treatment 14588.2 255.0 0.23 0.2303 1.0 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 I24 compound treatment 12790.3 -1540.0 -1.39 -1.3932 -1.0 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J01 compound treatment 14494.4 161.0 0.15 0.1456 1.0 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J02 compound treatment 14265.3 -67.8 -0.06 -0.0612 -1.0 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J03 compound treatment 15387.1 1050.0 0.95 0.9518 1.0 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J04 compound treatment 15012.2 679.0 0.61 0.6132 1.0 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J05 mock treatment 15373.9 1040.0 0.94 0.9398 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J06 mock treatment 14967.1 634.0 0.57 0.5725 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J07 compound treatment 14170.5 -163.0 -0.15 -0.1468 -1.0 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J08 compound treatment 14628.7 296.0 0.27 0.2669 1.0 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J09 compound treatment 14615.5 282.0 0.25 0.255 1.0 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J10 compound treatment 14444.4 111.0 0.1 0.1005 1.0 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J11 compound treatment 14598.2 265.0 0.24 0.2394 1.0 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J12 compound treatment 14237.4 -95.7 -0.09 -0.0864 -1.0 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J13 compound treatment 14457.5 124.0 0.11 0.1123 1.0 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J14 compound treatment 12906.1 -1430.0 -1.29 -1.2886 -1.0 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J15 compound treatment 14441.6 108.0 0.1 0.098 1.0 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J16 compound treatment 14201.5 -132.0 -0.12 -0.1188 -1.0 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J17 compound treatment 14632.7 300.0 0.27 0.2705 1.0 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J18 compound treatment 14599.0 266.0 0.24 0.2401 1.0 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J19 compound treatment 14736.9 404.0 0.36 0.3646 1.0 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J20 compound treatment 14954.7 622.0 0.56 0.5613 1.0 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J21 mock treatment 14740.5 407.0 0.37 0.3679 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J22 mock treatment 14530.1 197.0 0.18 0.1779 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J23 compound treatment 13635.5 -698.0 -0.63 -0.63 -1.0 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 J24 compound treatment 13927.0 -406.0 -0.37 -0.3667 -1.0 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K01 compound treatment 14067.0 -266.0 -0.24 -0.2403 -1.0 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K02 compound treatment 13163.0 -1170.0 -1.06 -1.0566 -1.0 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K03 compound treatment 14669.8 337.0 0.3 0.304 1.0 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K04 compound treatment 14800.9 468.0 0.42 0.4224 1.0 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K05 compound treatment 14582.5 249.0 0.23 0.2252 1.0 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K06 compound treatment 14635.0 302.0 0.27 0.2726 1.0 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K07 mock treatment 14052.6 -281.0 -0.25 -0.2533 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K08 mock treatment 14287.9 -45.2 -0.04 -0.0408 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K09 compound treatment 13965.3 -368.0 -0.33 -0.3321 -1.0 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K10 compound treatment 13799.2 -534.0 -0.48 -0.4821 -1.0 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K11 compound treatment 13333.3 -1000.0 -0.9 -0.9028 -1.0 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K12 compound treatment 14118.0 -215.0 -0.19 -0.1942 -1.0 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K13 compound treatment 13557.0 -776.0 -0.7 -0.7008 -1.0 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K14 compound treatment 13516.8 -816.0 -0.74 -0.7371 -1.0 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K15 mock treatment 14004.9 -328.0 -0.3 -0.2964 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K16 mock treatment 14194.1 -139.0 -0.13 -0.1255 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K17 compound treatment 14089.6 -244.0 -0.22 -0.2199 -1.0 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K18 compound treatment 14112.2 -221.0 -0.2 -0.1995 -1.0 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K19 compound treatment 14426.0 92.9 0.08 0.0839 1.0 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K20 compound treatment 14241.2 -91.9 -0.08 -0.083 -1.0 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K21 compound treatment 14171.7 -161.0 -0.15 -0.1458 -1.0 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K22 compound treatment 13996.7 -336.0 -0.3 -0.3038 -1.0 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K23 mock treatment 14115.4 -218.0 -0.2 -0.1966 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 K24 mock treatment 13731.4 -602.0 -0.54 -0.5434 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L01 compound treatment 14204.6 -129.0 -0.12 -0.116 -1.0 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L02 compound treatment 14352.2 19.1 0.02 0.0172 1.0 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L03 compound treatment 14514.8 182.0 0.16 0.1641 1.0 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L04 compound treatment 14573.3 240.0 0.22 0.2169 1.0 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L05 compound treatment 14079.5 -254.0 -0.23 -0.229 -1.0 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L06 compound treatment 14883.4 550.0 0.5 0.4969 1.0 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L07 mock treatment 13761.7 -571.0 -0.52 -0.516 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L08 mock treatment 13882.1 -451.0 -0.41 -0.4073 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L09 compound treatment 14407.7 74.6 0.07 0.0674 1.0 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L10 compound treatment 14706.2 373.0 0.34 0.3369 1.0 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L11 compound treatment 13604.6 -729.0 -0.66 -0.6579 -1.0 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L12 compound treatment 14369.0 35.9 0.03 0.0324 1.0 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L13 compound treatment 14048.6 -285.0 -0.26 -0.2569 -1.0 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L14 compound treatment 13096.1 -1240.0 -1.12 -1.117 -1.0 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L15 mock treatment 14460.5 127.0 0.12 0.115 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L16 mock treatment 14025.7 -307.0 -0.28 -0.2776 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L17 compound treatment 14617.8 285.0 0.26 0.2571 1.0 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L18 compound treatment 14112.7 -220.0 -0.2 -0.199 -1.0 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L19 compound treatment 14236.4 -96.7 -0.09 -0.0873 -1.0 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L20 compound treatment 14465.5 132.0 0.12 0.1195 1.0 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L21 compound treatment 14502.3 169.0 0.15 0.1528 1.0 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L22 compound treatment 14169.6 -164.0 -0.15 -0.1477 -1.0 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L23 mock treatment 14369.3 36.2 0.03 0.0327 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 L24 mock treatment 13098.3 -1230.0 -1.12 -1.115 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M01 compound treatment 13546.9 -786.0 -0.71 -0.71 -1.0 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M02 compound treatment 13669.0 -664.0 -0.6 -0.5997 -1.0 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M03 compound treatment 14809.1 476.0 0.43 0.4298 1.0 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M04 compound treatment 14424.6 91.5 0.08 0.0826 1.0 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M05 compound treatment 14508.3 175.0 0.16 0.1582 1.0 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M06 compound treatment 14017.4 -316.0 -0.29 -0.2851 -1.0 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M07 compound treatment 13332.7 -1000.0 -0.9 -0.9034 -1.0 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M08 compound treatment 13987.2 -346.0 -0.31 -0.3124 -1.0 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M09 mock treatment 14388.3 55.2 0.05 0.0498 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M10 mock treatment 13941.3 -392.0 -0.35 -0.3538 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M11 compound treatment 14074.1 -259.0 -0.23 -0.2339 -1.0 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M12 compound treatment 13097.8 -1240.0 -1.12 -1.1155 -1.0 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M13 mock treatment 14539.4 206.0 0.19 0.1863 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M14 mock treatment 13614.5 -719.0 -0.65 -0.6489 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M15 compound treatment 13700.3 -633.0 -0.57 -0.5714 -1.0 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M16 compound treatment 13661.6 -672.0 -0.61 -0.6064 -1.0 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M17 compound treatment 13496.6 -837.0 -0.76 -0.7554 -1.0 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M18 compound treatment 13948.6 -385.0 -0.35 -0.3472 -1.0 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M19 compound treatment 14275.5 -57.6 -0.05 -0.052 -1.0 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M20 compound treatment 13731.9 -601.0 -0.54 -0.5429 -1.0 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M21 compound treatment 14646.9 314.0 0.28 0.2834 1.0 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M22 compound treatment 13529.4 -804.0 -0.73 -0.7258 -1.0 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M23 compound treatment 14215.2 -118.0 -0.11 -0.1065 -1.0 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 M24 compound treatment 13163.0 -1170.0 -1.06 -1.0566 -1.0 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N01 compound treatment 14042.9 -290.0 -0.26 -0.2621 -1.0 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N02 compound treatment 13913.9 -419.0 -0.38 -0.3786 -1.0 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N03 compound treatment 13396.3 -937.0 -0.85 -0.846 -1.0 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N04 compound treatment 14700.7 368.0 0.33 0.3319 1.0 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N05 compound treatment 13639.4 -694.0 -0.63 -0.6264 -1.0 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N06 compound treatment 14663.8 331.0 0.3 0.2986 1.0 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N07 compound treatment 14093.2 -240.0 -0.22 -0.2166 -1.0 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N08 compound treatment 13816.3 -517.0 -0.47 -0.4667 -1.0 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N09 mock treatment 14588.7 256.0 0.23 0.2308 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N10 mock treatment 13840.9 -492.0 -0.44 -0.4445 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N11 compound treatment 13808.2 -525.0 -0.47 -0.474 -1.0 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N12 compound treatment 14555.7 223.0 0.2 0.201 1.0 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N13 mock treatment 14083.2 -250.0 -0.23 -0.2257 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N14 mock treatment 13870.4 -463.0 -0.42 -0.4178 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N15 compound treatment 14082.1 -251.0 -0.23 -0.2267 -1.0 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N16 compound treatment 14019.8 -313.0 -0.28 -0.2829 -1.0 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N17 compound treatment 13466.8 -866.0 -0.78 -0.7823 -1.0 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N18 compound treatment 14095.1 -238.0 -0.21 -0.2149 -1.0 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N19 compound treatment 13825.7 -507.0 -0.46 -0.4582 -1.0 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N20 compound treatment 14783.1 450.0 0.41 0.4063 1.0 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N21 compound treatment 14337.3 4.19 0.0 0.0038 1.0 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N22 compound treatment 14333.2 0.0859 0.0 1.0E-4 1.0 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N23 compound treatment 13878.2 -455.0 -0.41 -0.4108 -1.0 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 N24 compound treatment 13807.7 -525.0 -0.47 -0.4745 -1.0 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O01 compound treatment 13779.7 -553.0 -0.5 -0.4997 -1.0 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O02 compound treatment 12674.2 -1660.0 -1.5 -1.498 -1.0 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O03 compound treatment 13944.1 -389.0 -0.35 -0.3513 -1.0 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O04 compound treatment 13366.4 -967.0 -0.87 -0.873 -1.0 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O05 compound treatment 14016.7 -316.0 -0.29 -0.2857 -1.0 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O06 compound treatment 13931.7 -401.0 -0.36 -0.3625 -1.0 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O07 compound treatment 12941.7 -1390.0 -1.26 -1.2565 -1.0 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O08 compound treatment 13193.9 -1140.0 -1.03 -1.0287 -1.0 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O09 compound treatment 13192.3 -1140.0 -1.03 -1.0302 -1.0 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O10 compound treatment 13469.4 -864.0 -0.78 -0.7799 -1.0 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O11 mock treatment 13615.7 -717.0 -0.65 -0.6478 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O12 mock treatment 13682.9 -650.0 -0.59 -0.5871 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O13 compound treatment 13785.9 -547.0 -0.49 -0.4941 -1.0 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O14 compound treatment 13375.7 -957.0 -0.86 -0.8646 -1.0 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O15 compound treatment 14224.9 -108.0 -0.1 -0.0977 -1.0 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O16 compound treatment 13857.6 -476.0 -0.43 -0.4294 -1.0 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O17 compound treatment 14172.2 -161.0 -0.15 -0.1453 -1.0 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O18 compound treatment 12853.1 -1480.0 -1.34 -1.3365 -1.0 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O19 compound treatment 14145.4 -188.0 -0.17 -0.1695 -1.0 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O20 compound treatment 13304.9 -1030.0 -0.93 -0.9285 -1.0 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O21 compound treatment 14112.1 -221.0 -0.2 -0.1996 -1.0 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O22 compound treatment 13806.7 -526.0 -0.48 -0.4754 -1.0 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O23 compound treatment 13608.5 -725.0 -0.65 -0.6543 -1.0 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 O24 compound treatment 13254.2 -1080.0 -0.97 -0.9743 -1.0 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P01 compound treatment 13705.8 -627.0 -0.57 -0.5665 -1.0 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P02 compound treatment 13156.7 -1180.0 -1.06 -1.0623 -1.0 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P03 compound treatment 14159.3 -174.0 -0.16 -0.157 -1.0 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P04 compound treatment 13612.8 -720.0 -0.65 -0.6504 -1.0 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P05 compound treatment 13985.9 -347.0 -0.31 -0.3135 -1.0 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P06 compound treatment 13637.1 -696.0 -0.63 -0.6285 -1.0 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P07 compound treatment 13278.2 -1050.0 -0.95 -0.9526 -1.0 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P08 compound treatment 12768.7 -1560.0 -1.41 -1.4127 -1.0 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P09 compound treatment 13770.2 -563.0 -0.51 -0.5083 -1.0 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P10 compound treatment 13906.8 -426.0 -0.38 -0.385 -1.0 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P11 mock treatment 14040.9 -292.0 -0.26 -0.2639 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P12 mock treatment 13988.7 -344.0 -0.31 -0.311 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P13 compound treatment 14376.2 43.1 0.04 0.0389 1.0 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P14 compound treatment 13953.3 -380.0 -0.34 -0.343 -1.0 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P15 compound treatment 14134.6 -199.0 -0.18 -0.1793 -1.0 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P16 compound treatment 13836.0 -497.0 -0.45 -0.4489 -1.0 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P17 compound treatment 14190.3 -143.0 -0.13 -0.129 -1.0 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P18 compound treatment 13919.1 -414.0 -0.37 -0.3739 -1.0 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P19 compound treatment 14161.3 -172.0 -0.16 -0.1551 -1.0 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P20 compound treatment 13269.9 -1060.0 -0.96 -0.9601 -1.0 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P21 compound treatment 12643.1 -1690.0 -1.53 -1.5261 -1.0 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P22 compound treatment 13416.5 -917.0 -0.83 -0.8277 -1.0 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P23 compound treatment 13563.6 -770.0 -0.69 -0.6949 -1.0 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2094 P24 compound treatment 13114.9 -1220.0 -1.1 -1.1001 -1.0 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A01 compound treatment 13163.1 -1080.0 -0.98 -0.9794 -1.0 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A02 compound treatment 13609.5 -638.0 -0.58 -0.5763 -1.0 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A03 compound treatment 14085.2 -163.0 -0.15 -0.1468 -1.0 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A04 compound treatment 14055.9 -192.0 -0.17 -0.1732 -1.0 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A05 compound treatment 14272.1 24.4 0.02 0.022 1.0 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A06 compound treatment 14150.8 -96.9 -0.09 -0.0875 -1.0 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A07 compound treatment 14152.0 -95.7 -0.09 -0.0865 -1.0 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A08 compound treatment 13741.1 -507.0 -0.46 -0.4575 -1.0 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A09 compound treatment 14677.5 430.0 0.39 0.3881 1.0 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A10 compound treatment 14014.2 -234.0 -0.21 -0.2109 -1.0 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A11 compound treatment 13515.5 -732.0 -0.66 -0.6612 -1.0 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A12 compound treatment 13377.2 -871.0 -0.79 -0.7861 -1.0 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A13 mock treatment 13553.8 -694.0 -0.63 -0.6266 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A14 mock treatment 13213.9 -1030.0 -0.93 -0.9336 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A15 compound treatment 14038.7 -209.0 -0.19 -0.1888 -1.0 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A16 compound treatment 13769.2 -479.0 -0.43 -0.4321 -1.0 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A17 compound treatment 13811.9 -436.0 -0.39 -0.3936 -1.0 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A18 compound treatment 14045.9 -202.0 -0.18 -0.1823 -1.0 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A19 compound treatment 14833.9 586.0 0.53 0.5293 1.0 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A20 compound treatment 13954.6 -293.0 -0.26 -0.2647 -1.0 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A21 compound treatment 14650.9 403.0 0.36 0.3641 1.0 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A22 compound treatment 13620.2 -628.0 -0.57 -0.5667 -1.0 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A23 compound treatment 13810.2 -438.0 -0.4 -0.3951 -1.0 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 A24 compound treatment 11961.8 -2290.0 -2.06 -2.0642 -1.0 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B01 compound treatment 14470.3 223.0 0.2 0.201 1.0 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B02 compound treatment 14114.0 -134.0 -0.12 -0.1208 -1.0 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B03 compound treatment 14319.5 71.8 0.06 0.0648 1.0 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B04 compound treatment 14928.8 681.0 0.61 0.615 1.0 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B05 compound treatment 14021.2 -227.0 -0.2 -0.2046 -1.0 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B06 compound treatment 14403.4 156.0 0.14 0.1406 1.0 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B07 compound treatment 14305.2 57.5 0.05 0.0519 1.0 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B08 compound treatment 14374.2 126.0 0.11 0.1142 1.0 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B09 compound treatment 14164.4 -83.3 -0.08 -0.0753 -1.0 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B10 compound treatment 14181.6 -66.1 -0.06 -0.0597 -1.0 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B11 compound treatment 13892.2 -356.0 -0.32 -0.3211 -1.0 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B12 compound treatment 13403.4 -844.0 -0.76 -0.7625 -1.0 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B13 mock treatment 13964.9 -283.0 -0.26 -0.2554 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B14 mock treatment 14118.6 -129.0 -0.12 -0.1166 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B15 compound treatment 14145.5 -102.0 -0.09 -0.0923 -1.0 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B16 compound treatment 14146.8 -101.0 -0.09 -0.0912 -1.0 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B17 compound treatment 14090.3 -157.0 -0.14 -0.1422 -1.0 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B18 compound treatment 13697.3 -550.0 -0.5 -0.4971 -1.0 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B19 compound treatment 14376.7 129.0 0.12 0.1164 1.0 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B20 compound treatment 14018.2 -230.0 -0.21 -0.2073 -1.0 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B21 compound treatment 14317.8 70.1 0.06 0.0633 1.0 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B22 compound treatment 13890.7 -357.0 -0.32 -0.3224 -1.0 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B23 compound treatment 13940.5 -307.0 -0.28 -0.2774 -1.0 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 B24 compound treatment 12952.2 -1300.0 -1.17 -1.1699 -1.0 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C01 compound treatment 14512.0 264.0 0.24 0.2386 1.0 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C02 compound treatment 14723.6 476.0 0.43 0.4297 1.0 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C03 compound treatment 14419.7 172.0 0.16 0.1553 1.0 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C04 compound treatment 13399.1 -849.0 -0.77 -0.7663 -1.0 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C05 compound treatment 14835.7 588.0 0.53 0.5309 1.0 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C06 compound treatment 14696.2 448.0 0.4 0.405 1.0 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C07 compound treatment 14070.0 -178.0 -0.16 -0.1605 -1.0 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C08 compound treatment 14276.7 29.0 0.03 0.0261 1.0 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C09 compound treatment 14149.8 -97.9 -0.09 -0.0884 -1.0 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C10 compound treatment 13737.7 -510.0 -0.46 -0.4606 -1.0 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C11 mock treatment 14143.0 -105.0 -0.09 -0.0946 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C12 mock treatment 13745.0 -503.0 -0.45 -0.454 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C13 compound treatment 14109.6 -138.0 -0.12 -0.1247 -1.0 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C14 compound treatment 13902.7 -345.0 -0.31 -0.3116 -1.0 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C15 mock treatment 14653.2 405.0 0.37 0.3661 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C16 mock treatment 13490.3 -757.0 -0.68 -0.684 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C17 compound treatment 14549.5 302.0 0.27 0.2725 1.0 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C18 compound treatment 14135.0 -113.0 -0.1 -0.1018 -1.0 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C19 compound treatment 14283.4 35.7 0.03 0.0322 1.0 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C20 compound treatment 13950.3 -297.0 -0.27 -0.2686 -1.0 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C21 compound treatment 14646.5 399.0 0.36 0.3601 1.0 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C22 compound treatment 14436.6 189.0 0.17 0.1705 1.0 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C23 compound treatment 14219.1 -28.6 -0.03 -0.0259 -1.0 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 C24 compound treatment 14090.7 -157.0 -0.14 -0.1418 -1.0 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D01 compound treatment 14726.6 479.0 0.43 0.4324 1.0 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D02 compound treatment 15005.3 758.0 0.68 0.6841 1.0 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D03 compound treatment 14497.7 250.0 0.23 0.2257 1.0 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D04 compound treatment 14684.1 436.0 0.39 0.394 1.0 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D05 compound treatment 14534.0 286.0 0.26 0.2585 1.0 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D06 compound treatment 14994.9 747.0 0.67 0.6747 1.0 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D07 compound treatment 13937.3 -310.0 -0.28 -0.2803 -1.0 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D08 compound treatment 14903.4 656.0 0.59 0.5921 1.0 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D09 compound treatment 14296.0 48.3 0.04 0.0436 1.0 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D10 compound treatment 14771.8 524.0 0.47 0.4732 1.0 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D11 mock treatment 13583.0 -665.0 -0.6 -0.6003 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D12 mock treatment 14441.0 193.0 0.17 0.1745 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D13 compound treatment 14131.1 -117.0 -0.11 -0.1053 -1.0 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D14 compound treatment 14029.4 -218.0 -0.2 -0.1972 -1.0 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D15 mock treatment 14038.2 -210.0 -0.19 -0.1892 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D16 mock treatment 13869.9 -378.0 -0.34 -0.3412 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D17 compound treatment 14311.8 64.1 0.06 0.0578 1.0 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D18 compound treatment 14092.2 -156.0 -0.14 -0.1405 -1.0 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D19 compound treatment 14818.1 570.0 0.52 0.515 1.0 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D20 compound treatment 14915.6 668.0 0.6 0.6031 1.0 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D21 compound treatment 14758.8 511.0 0.46 0.4615 1.0 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D22 compound treatment 14273.2 25.5 0.02 0.023 1.0 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D23 compound treatment 14051.4 -196.0 -0.18 -0.1773 -1.0 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 D24 compound treatment 15094.4 847.0 0.76 0.7645 1.0 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E01 mock treatment 13856.4 -391.0 -0.35 -0.3534 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E02 mock treatment 14940.3 693.0 0.63 0.6254 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E03 compound treatment 14834.0 586.0 0.53 0.5294 1.0 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E04 compound treatment 14195.5 -52.2 -0.05 -0.0472 -1.0 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E05 compound treatment 13614.2 -634.0 -0.57 -0.5721 -1.0 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E06 compound treatment 15228.4 981.0 0.89 0.8855 1.0 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E07 compound treatment 14094.5 -153.0 -0.14 -0.1384 -1.0 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E08 compound treatment 14383.7 136.0 0.12 0.1228 1.0 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E09 mock treatment 13921.2 -327.0 -0.29 -0.2949 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E10 mock treatment 13538.7 -709.0 -0.64 -0.6403 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E11 compound treatment 13537.3 -710.0 -0.64 -0.6415 -1.0 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E12 compound treatment 13870.7 -377.0 -0.34 -0.3405 -1.0 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E13 compound treatment 13880.5 -367.0 -0.33 -0.3316 -1.0 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E14 compound treatment 13955.2 -293.0 -0.26 -0.2642 -1.0 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E15 compound treatment 13835.9 -412.0 -0.37 -0.3719 -1.0 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E16 compound treatment 13808.2 -440.0 -0.4 -0.3969 -1.0 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E17 mock treatment 13962.8 -285.0 -0.26 -0.2573 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E18 mock treatment 14109.0 -139.0 -0.13 -0.1253 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E19 compound treatment 14483.8 236.0 0.21 0.2132 1.0 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E20 compound treatment 14169.0 -78.7 -0.07 -0.0711 -1.0 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E21 compound treatment 14658.2 410.0 0.37 0.3706 1.0 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E22 compound treatment 14462.5 215.0 0.19 0.1939 1.0 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E23 compound treatment 13285.7 -962.0 -0.87 -0.8687 -1.0 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 E24 compound treatment 13553.1 -695.0 -0.63 -0.6273 -1.0 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F01 mock treatment 14616.8 369.0 0.33 0.3333 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F02 mock treatment 14640.6 393.0 0.35 0.3548 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F03 compound treatment 14922.9 675.0 0.61 0.6097 1.0 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F04 compound treatment 15206.8 959.0 0.87 0.866 1.0 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F05 compound treatment 15030.8 783.0 0.71 0.7071 1.0 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F06 compound treatment 15357.7 1110.0 1.0 1.0023 1.0 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F07 compound treatment 14894.5 647.0 0.58 0.584 1.0 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F08 compound treatment 14634.0 386.0 0.35 0.3488 1.0 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F09 mock treatment 14228.5 -19.2 -0.02 -0.0174 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F10 mock treatment 14225.7 -22.0 -0.02 -0.0199 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F11 compound treatment 14070.8 -177.0 -0.16 -0.1598 -1.0 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F12 compound treatment 14465.9 218.0 0.2 0.197 1.0 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F13 compound treatment 13689.6 -558.0 -0.5 -0.504 -1.0 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F14 compound treatment 14191.1 -56.6 -0.05 -0.0512 -1.0 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F15 compound treatment 14098.0 -150.0 -0.14 -0.1352 -1.0 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F16 compound treatment 14312.4 64.7 0.06 0.0584 1.0 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F17 mock treatment 14229.4 -18.3 -0.02 -0.0166 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F18 mock treatment 14032.6 -215.0 -0.19 -0.1943 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F19 compound treatment 14573.6 326.0 0.29 0.2942 1.0 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F20 compound treatment 15178.2 930.0 0.84 0.8402 1.0 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F21 compound treatment 14700.1 452.0 0.41 0.4085 1.0 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F22 compound treatment 15448.1 1200.0 1.08 1.0839 1.0 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F23 compound treatment 14826.1 578.0 0.52 0.5223 1.0 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 F24 compound treatment 13881.8 -366.0 -0.33 -0.3305 -1.0 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G01 compound treatment 14519.1 271.0 0.25 0.245 1.0 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G02 compound treatment 14747.6 500.0 0.45 0.4514 1.0 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G03 mock treatment 14825.9 578.0 0.52 0.5221 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G04 mock treatment 15458.6 1210.0 1.09 1.0934 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G05 compound treatment 13865.3 -382.0 -0.35 -0.3454 -1.0 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G06 compound treatment 14861.4 614.0 0.55 0.5541 1.0 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G07 compound treatment 14011.7 -236.0 -0.21 -0.2132 -1.0 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G08 compound treatment 14823.5 576.0 0.52 0.5199 1.0 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G09 compound treatment 13893.7 -354.0 -0.32 -0.3197 -1.0 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G10 compound treatment 14269.6 21.9 0.02 0.0197 1.0 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G11 compound treatment 13952.0 -296.0 -0.27 -0.2671 -1.0 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G12 compound treatment 14612.2 364.0 0.33 0.3291 1.0 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G13 compound treatment 13840.0 -408.0 -0.37 -0.3682 -1.0 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G14 compound treatment 14145.0 -103.0 -0.09 -0.0928 -1.0 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G15 compound treatment 13892.8 -355.0 -0.32 -0.3205 -1.0 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G16 compound treatment 14381.3 134.0 0.12 0.1206 1.0 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G17 compound treatment 14016.8 -231.0 -0.21 -0.2085 -1.0 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G18 compound treatment 14699.6 452.0 0.41 0.408 1.0 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G19 mock treatment 14589.5 342.0 0.31 0.3086 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G20 mock treatment 14974.0 726.0 0.66 0.6558 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G21 compound treatment 14516.4 269.0 0.24 0.2426 1.0 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G22 compound treatment 15007.8 760.0 0.69 0.6863 1.0 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G23 compound treatment 14346.7 99.0 0.09 0.0894 1.0 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 G24 compound treatment 14475.8 228.0 0.21 0.2059 1.0 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H01 compound treatment 14455.3 208.0 0.19 0.1874 1.0 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H02 compound treatment 15073.5 826.0 0.75 0.7457 1.0 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H03 mock treatment 14534.0 286.0 0.26 0.2585 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H04 mock treatment 15291.1 1040.0 0.94 0.9422 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H05 compound treatment 14800.5 553.0 0.5 0.4991 1.0 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H06 compound treatment 15303.2 1060.0 0.95 0.9531 1.0 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H07 compound treatment 14936.5 689.0 0.62 0.622 1.0 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H08 compound treatment 14821.3 574.0 0.52 0.5179 1.0 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H09 compound treatment 13747.3 -500.0 -0.45 -0.4519 -1.0 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H10 compound treatment 14245.4 -2.35 0.0 -0.0021 -1.0 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H11 compound treatment 13866.6 -381.0 -0.34 -0.3442 -1.0 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H12 compound treatment 14487.7 240.0 0.22 0.2167 1.0 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H13 compound treatment 14210.4 -37.3 -0.03 -0.0337 -1.0 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H14 compound treatment 13881.5 -366.0 -0.33 -0.3307 -1.0 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H15 compound treatment 14118.4 -129.0 -0.12 -0.1168 -1.0 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H16 compound treatment 14559.8 312.0 0.28 0.2818 1.0 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H17 compound treatment 14412.4 165.0 0.15 0.1487 1.0 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H18 compound treatment 14346.5 98.8 0.09 0.0892 1.0 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H19 mock treatment 14860.6 613.0 0.55 0.5534 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H20 mock treatment 14685.9 438.0 0.4 0.3957 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H21 compound treatment 14935.4 688.0 0.62 0.621 1.0 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H22 compound treatment 15382.9 1140.0 1.03 1.0251 1.0 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H23 compound treatment 14513.3 266.0 0.24 0.2398 1.0 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 H24 compound treatment 13629.2 -619.0 -0.56 -0.5586 -1.0 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I01 compound treatment 13609.0 -639.0 -0.58 -0.5768 -1.0 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I02 compound treatment 13169.0 -1080.0 -0.97 -0.9741 -1.0 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I03 compound treatment 14551.4 304.0 0.27 0.2742 1.0 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I04 compound treatment 14648.3 401.0 0.36 0.3617 1.0 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I05 mock treatment 14403.8 156.0 0.14 0.1409 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I06 mock treatment 15084.1 836.0 0.76 0.7552 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I07 compound treatment 13937.8 -310.0 -0.28 -0.2799 -1.0 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I08 compound treatment 14228.7 -19.0 -0.02 -0.0172 -1.0 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I09 compound treatment 13491.7 -756.0 -0.68 -0.6827 -1.0 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I10 compound treatment 13837.9 -410.0 -0.37 -0.3701 -1.0 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I11 compound treatment 13670.8 -577.0 -0.52 -0.521 -1.0 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I12 compound treatment 14088.9 -159.0 -0.14 -0.1434 -1.0 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I13 compound treatment 13699.7 -548.0 -0.49 -0.4949 -1.0 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I14 compound treatment 14167.7 -80.0 -0.07 -0.0723 -1.0 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I15 compound treatment 14080.7 -167.0 -0.15 -0.1508 -1.0 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I16 compound treatment 13990.1 -258.0 -0.23 -0.2327 -1.0 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I17 compound treatment 13570.7 -677.0 -0.61 -0.6114 -1.0 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I18 compound treatment 14369.5 122.0 0.11 0.1099 1.0 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I19 compound treatment 14292.0 44.3 0.04 0.04 1.0 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I20 compound treatment 14659.6 412.0 0.37 0.3719 1.0 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I21 mock treatment 14498.2 250.0 0.23 0.2262 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I22 mock treatment 14123.6 -124.0 -0.11 -0.1121 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I23 compound treatment 13984.3 -263.0 -0.24 -0.2379 -1.0 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 I24 compound treatment 13315.0 -933.0 -0.84 -0.8423 -1.0 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J01 compound treatment 14218.5 -29.2 -0.03 -0.0264 -1.0 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J02 compound treatment 14247.7 -0.0453 0.0 0.0 -1.0 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J03 compound treatment 15157.5 910.0 0.82 0.8215 1.0 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J04 compound treatment 14599.5 352.0 0.32 0.3176 1.0 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J05 mock treatment 14865.8 618.0 0.56 0.5581 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J06 mock treatment 15334.4 1090.0 0.98 0.9813 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J07 compound treatment 14455.1 207.0 0.19 0.1872 1.0 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J08 compound treatment 15289.2 1040.0 0.94 0.9404 1.0 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J09 compound treatment 15535.2 1290.0 1.16 1.1626 1.0 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J10 compound treatment 14729.8 482.0 0.44 0.4353 1.0 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J11 compound treatment 13985.2 -263.0 -0.24 -0.2371 -1.0 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J12 compound treatment 14390.0 142.0 0.13 0.1285 1.0 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J13 compound treatment 13790.8 -457.0 -0.41 -0.4126 -1.0 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J14 compound treatment 14131.5 -116.0 -0.1 -0.105 -1.0 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J15 compound treatment 14057.2 -191.0 -0.17 -0.1721 -1.0 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J16 compound treatment 14953.1 705.0 0.64 0.6369 1.0 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J17 compound treatment 13529.2 -719.0 -0.65 -0.6489 -1.0 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J18 compound treatment 14665.4 418.0 0.38 0.3771 1.0 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J19 compound treatment 14906.9 659.0 0.6 0.5952 1.0 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J20 compound treatment 14976.4 729.0 0.66 0.658 1.0 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J21 mock treatment 14673.5 426.0 0.38 0.3845 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J22 mock treatment 14580.3 333.0 0.3 0.3003 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J23 compound treatment 13590.9 -657.0 -0.59 -0.5931 -1.0 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 J24 compound treatment 13343.8 -904.0 -0.82 -0.8163 -1.0 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K01 compound treatment 13564.0 -684.0 -0.62 -0.6174 -1.0 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K02 compound treatment 13824.1 -424.0 -0.38 -0.3826 -1.0 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K03 compound treatment 14855.0 607.0 0.55 0.5484 1.0 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K04 compound treatment 15407.9 1160.0 1.05 1.0476 1.0 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K05 compound treatment 14682.6 435.0 0.39 0.3927 1.0 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K06 compound treatment 14553.2 305.0 0.28 0.2758 1.0 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K07 mock treatment 13984.6 -263.0 -0.24 -0.2376 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K08 mock treatment 14787.1 539.0 0.49 0.487 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K09 compound treatment 13911.8 -336.0 -0.3 -0.3034 -1.0 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K10 compound treatment 14202.5 -45.2 -0.04 -0.0409 -1.0 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K11 compound treatment 13564.0 -684.0 -0.62 -0.6174 -1.0 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K12 compound treatment 14563.5 316.0 0.29 0.2851 1.0 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K13 compound treatment 13916.9 -331.0 -0.3 -0.2988 -1.0 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K14 compound treatment 13873.8 -374.0 -0.34 -0.3377 -1.0 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K15 mock treatment 14105.7 -142.0 -0.13 -0.1283 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K16 mock treatment 14363.8 116.0 0.1 0.1048 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K17 compound treatment 14099.4 -148.0 -0.13 -0.134 -1.0 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K18 compound treatment 14044.0 -204.0 -0.18 -0.184 -1.0 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K19 compound treatment 14745.0 497.0 0.45 0.449 1.0 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K20 compound treatment 13444.1 -804.0 -0.73 -0.7257 -1.0 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K21 compound treatment 14658.8 411.0 0.37 0.3712 1.0 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K22 compound treatment 14636.0 388.0 0.35 0.3506 1.0 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K23 mock treatment 14006.4 -241.0 -0.22 -0.2179 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 K24 mock treatment 13088.2 -1160.0 -1.05 -1.0471 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L01 compound treatment 14096.8 -151.0 -0.14 -0.1363 -1.0 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L02 compound treatment 15272.0 1020.0 0.92 0.9249 1.0 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L03 compound treatment 14105.9 -142.0 -0.13 -0.1281 -1.0 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L04 compound treatment 14865.2 617.0 0.56 0.5576 1.0 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L05 compound treatment 14257.1 9.35 0.01 0.0084 1.0 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L06 compound treatment 14630.3 383.0 0.35 0.3454 1.0 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L07 mock treatment 14251.2 3.45 0.0 0.0031 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L08 mock treatment 14827.4 580.0 0.52 0.5234 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L09 compound treatment 13416.9 -831.0 -0.75 -0.7503 -1.0 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L10 compound treatment 14651.7 404.0 0.36 0.3648 1.0 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L11 compound treatment 13397.1 -851.0 -0.77 -0.7681 -1.0 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L12 compound treatment 14473.7 226.0 0.2 0.204 1.0 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L13 compound treatment 13882.7 -365.0 -0.33 -0.3296 -1.0 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L14 compound treatment 13776.9 -471.0 -0.43 -0.4252 -1.0 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L15 mock treatment 14027.7 -220.0 -0.2 -0.1987 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L16 mock treatment 14143.5 -104.0 -0.09 -0.0941 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L17 compound treatment 14199.8 -47.9 -0.04 -0.0433 -1.0 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L18 compound treatment 14695.1 447.0 0.4 0.404 1.0 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L19 compound treatment 14728.5 481.0 0.43 0.4341 1.0 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L20 compound treatment 14397.0 149.0 0.13 0.1348 1.0 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L21 compound treatment 14551.7 304.0 0.27 0.2745 1.0 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L22 compound treatment 14108.9 -139.0 -0.13 -0.1254 -1.0 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L23 mock treatment 13896.7 -351.0 -0.32 -0.317 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 L24 mock treatment 13275.3 -972.0 -0.88 -0.8781 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M01 compound treatment 14156.7 -91.0 -0.08 -0.0822 -1.0 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M02 compound treatment 14343.6 95.9 0.09 0.0866 1.0 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M03 compound treatment 14343.5 95.8 0.09 0.0865 1.0 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M04 compound treatment 14250.1 2.35 0.0 0.0021 1.0 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M05 compound treatment 13863.7 -384.0 -0.35 -0.3468 -1.0 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M06 compound treatment 13990.6 -257.0 -0.23 -0.2322 -1.0 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M07 compound treatment 13660.3 -587.0 -0.53 -0.5305 -1.0 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M08 compound treatment 14499.4 252.0 0.23 0.2272 1.0 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M09 mock treatment 14565.4 318.0 0.29 0.2868 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M10 mock treatment 14174.5 -73.2 -0.07 -0.0661 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M11 compound treatment 13682.4 -565.0 -0.51 -0.5105 -1.0 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M12 compound treatment 13560.2 -688.0 -0.62 -0.6209 -1.0 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M13 mock treatment 14007.7 -240.0 -0.22 -0.2168 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M14 mock treatment 14136.9 -111.0 -0.1 -0.1001 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M15 compound treatment 13919.9 -328.0 -0.3 -0.296 -1.0 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M16 compound treatment 14153.8 -93.9 -0.08 -0.0848 -1.0 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M17 compound treatment 14029.1 -219.0 -0.2 -0.1974 -1.0 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M18 compound treatment 13950.6 -297.0 -0.27 -0.2683 -1.0 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M19 compound treatment 14674.1 426.0 0.39 0.385 1.0 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M20 compound treatment 14404.8 157.0 0.14 0.1418 1.0 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M21 compound treatment 14986.5 739.0 0.67 0.6671 1.0 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M22 compound treatment 13717.2 -531.0 -0.48 -0.4791 -1.0 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M23 compound treatment 14066.1 -182.0 -0.16 -0.164 -1.0 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 M24 compound treatment 12886.8 -1360.0 -1.23 -1.2289 -1.0 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N01 compound treatment 13869.9 -378.0 -0.34 -0.3412 -1.0 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N02 compound treatment 14217.0 -30.7 -0.03 -0.0278 -1.0 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N03 compound treatment 14357.1 109.0 0.1 0.0987 1.0 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N04 compound treatment 13456.0 -792.0 -0.71 -0.715 -1.0 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N05 compound treatment 13879.1 -369.0 -0.33 -0.3329 -1.0 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N06 compound treatment 15198.3 951.0 0.86 0.8584 1.0 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N07 compound treatment 13842.5 -405.0 -0.37 -0.3659 -1.0 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N08 compound treatment 13970.6 -277.0 -0.25 -0.2503 -1.0 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N09 mock treatment 14109.9 -138.0 -0.12 -0.1245 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N10 mock treatment 14043.3 -204.0 -0.18 -0.1846 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N11 compound treatment 13360.5 -887.0 -0.8 -0.8012 -1.0 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N12 compound treatment 13951.3 -296.0 -0.27 -0.2677 -1.0 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N13 mock treatment 13913.0 -335.0 -0.3 -0.3023 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N14 mock treatment 14171.9 -75.8 -0.07 -0.0685 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N15 compound treatment 12877.8 -1370.0 -1.24 -1.2371 -1.0 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N16 compound treatment 14076.6 -171.0 -0.15 -0.1545 -1.0 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N17 compound treatment 14439.2 191.0 0.17 0.1729 1.0 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N18 compound treatment 14124.2 -124.0 -0.11 -0.1116 -1.0 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N19 compound treatment 13907.1 -341.0 -0.31 -0.3076 -1.0 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N20 compound treatment 14126.4 -121.0 -0.11 -0.1096 -1.0 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N21 compound treatment 14306.1 58.4 0.05 0.0527 1.0 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N22 compound treatment 14241.4 -6.35 -0.01 -0.0057 -1.0 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N23 compound treatment 14089.9 -158.0 -0.14 -0.1425 -1.0 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 N24 compound treatment 13160.9 -1090.0 -0.98 -0.9814 -1.0 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O01 compound treatment 14231.6 -16.1 -0.01 -0.0146 -1.0 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O02 compound treatment 13800.8 -447.0 -0.4 -0.4036 -1.0 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O03 compound treatment 14422.9 175.0 0.16 0.1582 1.0 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O04 compound treatment 13482.7 -765.0 -0.69 -0.6908 -1.0 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O05 compound treatment 13853.6 -394.0 -0.36 -0.3559 -1.0 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O06 compound treatment 13602.6 -645.0 -0.58 -0.5826 -1.0 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O07 compound treatment 13495.4 -752.0 -0.68 -0.6794 -1.0 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O08 compound treatment 13636.1 -612.0 -0.55 -0.5523 -1.0 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O09 compound treatment 13723.7 -524.0 -0.47 -0.4732 -1.0 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O10 compound treatment 13872.2 -376.0 -0.34 -0.3391 -1.0 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O11 mock treatment 13951.5 -296.0 -0.27 -0.2675 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O12 mock treatment 14159.4 -88.3 -0.08 -0.0798 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O13 compound treatment 14742.9 495.0 0.45 0.4471 1.0 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O14 compound treatment 13316.5 -931.0 -0.84 -0.8409 -1.0 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O15 compound treatment 13403.7 -844.0 -0.76 -0.7622 -1.0 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O16 compound treatment 12823.7 -1420.0 -1.29 -1.2859 -1.0 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O17 compound treatment 13819.0 -429.0 -0.39 -0.3872 -1.0 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O18 compound treatment 13183.3 -1060.0 -0.96 -0.9612 -1.0 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O19 compound treatment 14114.2 -134.0 -0.12 -0.1206 -1.0 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O20 compound treatment 13858.0 -390.0 -0.35 -0.3519 -1.0 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O21 compound treatment 14016.9 -231.0 -0.21 -0.2085 -1.0 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O22 compound treatment 13677.1 -571.0 -0.52 -0.5153 -1.0 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O23 compound treatment 13872.8 -375.0 -0.34 -0.3386 -1.0 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 O24 compound treatment 12743.8 -1500.0 -1.36 -1.3581 -1.0 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P01 compound treatment 13836.4 -411.0 -0.37 -0.3714 -1.0 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P02 compound treatment 13629.8 -618.0 -0.56 -0.558 -1.0 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P03 compound treatment 12719.2 -1530.0 -1.38 -1.3803 -1.0 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P04 compound treatment 13893.2 -355.0 -0.32 -0.3202 -1.0 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P05 compound treatment 13975.9 -272.0 -0.25 -0.2455 -1.0 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P06 compound treatment 13812.9 -435.0 -0.39 -0.3927 -1.0 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P07 compound treatment 13379.0 -869.0 -0.78 -0.7845 -1.0 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P08 compound treatment 13854.5 -393.0 -0.36 -0.3551 -1.0 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P09 compound treatment 14174.6 -73.1 -0.07 -0.0661 -1.0 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P10 compound treatment 14021.6 -226.0 -0.2 -0.2042 -1.0 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P11 mock treatment 13706.5 -541.0 -0.49 -0.4887 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P12 mock treatment 14258.0 10.3 0.01 0.0093 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P13 compound treatment 14135.3 -112.0 -0.1 -0.1015 -1.0 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P14 compound treatment 14266.3 18.6 0.02 0.0168 1.0 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P15 compound treatment 13773.0 -475.0 -0.43 -0.4287 -1.0 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P16 compound treatment 14646.0 398.0 0.36 0.3596 1.0 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P17 compound treatment 13793.0 -455.0 -0.41 -0.4106 -1.0 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P18 compound treatment 13455.2 -793.0 -0.72 -0.7157 -1.0 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P19 compound treatment 14091.8 -156.0 -0.14 -0.1408 -1.0 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P20 compound treatment 14066.3 -181.0 -0.16 -0.1638 -1.0 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P21 compound treatment 14310.0 62.3 0.06 0.0562 1.0 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P22 compound treatment 14194.3 -53.4 -0.05 -0.0483 -1.0 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P23 compound treatment 12990.9 -1260.0 -1.13 -1.1349 -1.0 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2095 P24 compound treatment 13583.0 -665.0 -0.6 -0.6003 -1.0 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A01 compound treatment 13142.7 -601.0 -0.54 -0.543 -1.0 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A02 compound treatment 12988.5 -755.0 -0.68 -0.6822 -1.0 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A03 compound treatment 13258.2 -486.0 -0.44 -0.4387 -1.0 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A04 compound treatment 12527.8 -1220.0 -1.1 -1.0982 -1.0 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A05 compound treatment 13808.1 64.1 0.06 0.0579 1.0 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A06 compound treatment 14068.2 324.0 0.29 0.2928 1.0 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A07 compound treatment 14385.6 642.0 0.58 0.5794 1.0 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A08 compound treatment 13243.1 -501.0 -0.45 -0.4523 -1.0 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A09 compound treatment 13904.8 161.0 0.15 0.1452 1.0 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A10 compound treatment 12829.1 -915.0 -0.83 -0.8262 -1.0 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A11 compound treatment 13076.0 -668.0 -0.6 -0.6032 -1.0 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A12 compound treatment 13196.6 -547.0 -0.49 -0.4943 -1.0 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A13 mock treatment 13807.7 63.7 0.06 0.0575 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A14 mock treatment 13075.5 -668.0 -0.6 -0.6036 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A15 compound treatment 13842.2 98.2 0.09 0.0887 1.0 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A16 compound treatment 13835.8 91.8 0.08 0.0829 1.0 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A17 compound treatment 13562.1 -182.0 -0.16 -0.1642 -1.0 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A18 compound treatment 13947.5 204.0 0.18 0.1838 1.0 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A19 compound treatment 13834.9 90.9 0.08 0.0821 1.0 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A20 compound treatment 13610.9 -133.0 -0.12 -0.1202 -1.0 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A21 compound treatment 13820.3 76.3 0.07 0.0689 1.0 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A22 compound treatment 13241.1 -503.0 -0.45 -0.4541 -1.0 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A23 compound treatment 13701.4 -42.6 -0.04 -0.0385 -1.0 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 A24 compound treatment 13340.1 -404.0 -0.36 -0.3647 -1.0 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B01 compound treatment 13441.8 -302.0 -0.27 -0.2729 -1.0 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B02 compound treatment 12993.3 -751.0 -0.68 -0.6779 -1.0 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B03 compound treatment 13416.5 -327.0 -0.3 -0.2957 -1.0 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B04 compound treatment 13707.4 -36.6 -0.03 -0.033 -1.0 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B05 compound treatment 13631.9 -112.0 -0.1 -0.1012 -1.0 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B06 compound treatment 14055.8 312.0 0.28 0.2816 1.0 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B07 compound treatment 13563.9 -180.0 -0.16 -0.1626 -1.0 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B08 compound treatment 13518.7 -225.0 -0.2 -0.2034 -1.0 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B09 compound treatment 13895.1 151.0 0.14 0.1365 1.0 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B10 compound treatment 13856.5 113.0 0.1 0.1016 1.0 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B11 compound treatment 14432.2 688.0 0.62 0.6215 1.0 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B12 compound treatment 13637.1 -107.0 -0.1 -0.0965 -1.0 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B13 mock treatment 13889.4 145.0 0.13 0.1313 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B14 mock treatment 13702.4 -41.6 -0.04 -0.0376 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B15 compound treatment 14005.0 261.0 0.24 0.2357 1.0 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B16 compound treatment 13626.3 -118.0 -0.11 -0.1063 -1.0 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B17 compound treatment 13694.8 -49.2 -0.04 -0.0444 -1.0 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B18 compound treatment 14059.5 316.0 0.28 0.2849 1.0 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B19 compound treatment 14325.2 581.0 0.52 0.5248 1.0 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B20 compound treatment 14289.2 545.0 0.49 0.4923 1.0 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B21 compound treatment 13977.0 233.0 0.21 0.2104 1.0 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B22 compound treatment 12571.8 -1170.0 -1.06 -1.0585 -1.0 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B23 compound treatment 13831.4 87.4 0.08 0.0789 1.0 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 B24 compound treatment 13500.8 -243.0 -0.22 -0.2196 -1.0 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C01 compound treatment 13236.4 -508.0 -0.46 -0.4584 -1.0 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C02 compound treatment 13776.1 32.1 0.03 0.029 1.0 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C03 compound treatment 13127.1 -617.0 -0.56 -0.5571 -1.0 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C04 compound treatment 13820.1 76.1 0.07 0.0687 1.0 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C05 compound treatment 14710.4 966.0 0.87 0.8727 1.0 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C06 compound treatment 13430.4 -314.0 -0.28 -0.2832 -1.0 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C07 compound treatment 13481.3 -263.0 -0.24 -0.2372 -1.0 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C08 compound treatment 13361.2 -383.0 -0.35 -0.3457 -1.0 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C09 compound treatment 13406.8 -337.0 -0.3 -0.3045 -1.0 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C10 compound treatment 13429.5 -314.0 -0.28 -0.284 -1.0 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C11 mock treatment 13535.0 -209.0 -0.19 -0.1887 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C12 mock treatment 13552.9 -191.0 -0.17 -0.1726 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C13 compound treatment 14039.7 296.0 0.27 0.267 1.0 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C14 compound treatment 13644.3 -99.7 -0.09 -0.09 -1.0 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C15 mock treatment 13940.8 197.0 0.18 0.1777 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C16 mock treatment 13997.2 253.0 0.23 0.2287 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C17 compound treatment 13823.7 79.7 0.07 0.072 1.0 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C18 compound treatment 13689.0 -55.0 -0.05 -0.0497 -1.0 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C19 compound treatment 14072.3 328.0 0.3 0.2965 1.0 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C20 compound treatment 13472.5 -271.0 -0.25 -0.2452 -1.0 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C21 compound treatment 13752.6 8.61 0.01 0.0078 1.0 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C22 compound treatment 13456.3 -288.0 -0.26 -0.2598 -1.0 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C23 compound treatment 14057.0 313.0 0.28 0.2827 1.0 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 C24 compound treatment 13740.8 -3.19 0.0 -0.0029 -1.0 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D01 compound treatment 13663.7 -80.3 -0.07 -0.0725 -1.0 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D02 compound treatment 13756.2 12.2 0.01 0.011 1.0 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D03 compound treatment 13931.2 187.0 0.17 0.1691 1.0 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D04 compound treatment 14144.4 400.0 0.36 0.3616 1.0 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D05 compound treatment 14406.9 663.0 0.6 0.5986 1.0 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D06 compound treatment 14087.5 344.0 0.31 0.3102 1.0 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D07 compound treatment 13787.6 43.6 0.04 0.0394 1.0 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D08 compound treatment 14472.1 728.0 0.66 0.6575 1.0 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D09 compound treatment 14200.0 456.0 0.41 0.4118 1.0 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D10 compound treatment 14036.5 293.0 0.26 0.2641 1.0 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D11 mock treatment 13753.5 9.51 0.01 0.0086 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D12 mock treatment 14145.0 401.0 0.36 0.3621 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D13 compound treatment 13719.4 -24.6 -0.02 -0.0222 -1.0 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D14 compound treatment 13670.1 -73.9 -0.07 -0.0667 -1.0 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D15 mock treatment 14276.3 532.0 0.48 0.4807 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D16 mock treatment 13966.3 222.0 0.2 0.2007 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D17 compound treatment 14016.1 272.0 0.25 0.2457 1.0 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D18 compound treatment 13882.0 138.0 0.12 0.1246 1.0 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D19 compound treatment 13971.3 227.0 0.21 0.2053 1.0 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D20 compound treatment 14165.3 421.0 0.38 0.3804 1.0 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D21 compound treatment 13103.0 -641.0 -0.58 -0.5788 -1.0 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D22 compound treatment 14145.9 402.0 0.36 0.3629 1.0 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D23 compound treatment 13940.3 196.0 0.18 0.1773 1.0 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 D24 compound treatment 13494.9 -249.0 -0.22 -0.2249 -1.0 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E01 mock treatment 13735.4 -8.59 -0.01 -0.0078 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E02 mock treatment 13456.2 -288.0 -0.26 -0.2599 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E03 compound treatment 13869.7 126.0 0.11 0.1135 1.0 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E04 compound treatment 13968.0 224.0 0.2 0.2023 1.0 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E05 compound treatment 13926.0 182.0 0.16 0.1644 1.0 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E06 compound treatment 14141.3 397.0 0.36 0.3588 1.0 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E07 compound treatment 14046.9 303.0 0.27 0.2735 1.0 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E08 compound treatment 13860.5 117.0 0.11 0.1052 1.0 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E09 mock treatment 13247.6 -496.0 -0.45 -0.4482 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E10 mock treatment 13445.5 -298.0 -0.27 -0.2695 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E11 compound treatment 14083.9 340.0 0.31 0.3069 1.0 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E12 compound treatment 13570.5 -173.0 -0.16 -0.1567 -1.0 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E13 compound treatment 14683.3 939.0 0.85 0.8482 1.0 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E14 compound treatment 13942.8 199.0 0.18 0.1795 1.0 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E15 compound treatment 14089.0 345.0 0.31 0.3115 1.0 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E16 compound treatment 13855.4 111.0 0.1 0.1006 1.0 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E17 mock treatment 14005.5 262.0 0.24 0.2361 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E18 mock treatment 13448.5 -295.0 -0.27 -0.2668 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E19 compound treatment 14160.2 416.0 0.38 0.3758 1.0 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E20 compound treatment 14503.0 759.0 0.69 0.6854 1.0 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E21 compound treatment 14502.0 758.0 0.68 0.6845 1.0 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E22 compound treatment 13777.3 33.3 0.03 0.0301 1.0 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E23 compound treatment 14487.9 744.0 0.67 0.6718 1.0 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 E24 compound treatment 13662.0 -82.0 -0.07 -0.074 -1.0 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F01 mock treatment 13677.9 -66.1 -0.06 -0.0597 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F02 mock treatment 13789.7 45.7 0.04 0.0413 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F03 compound treatment 14296.3 552.0 0.5 0.4987 1.0 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F04 compound treatment 14470.6 727.0 0.66 0.6561 1.0 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F05 compound treatment 14458.9 715.0 0.65 0.6456 1.0 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F06 compound treatment 14467.2 723.0 0.65 0.6531 1.0 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F07 compound treatment 14502.4 758.0 0.68 0.6849 1.0 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F08 compound treatment 14433.5 690.0 0.62 0.6226 1.0 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F09 mock treatment 14072.6 329.0 0.3 0.2967 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F10 mock treatment 14539.1 795.0 0.72 0.718 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F11 compound treatment 14573.2 829.0 0.75 0.7488 1.0 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F12 compound treatment 13972.5 229.0 0.21 0.2063 1.0 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F13 compound treatment 13571.0 -173.0 -0.16 -0.1562 -1.0 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F14 compound treatment 13986.2 242.0 0.22 0.2187 1.0 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F15 compound treatment 14360.1 616.0 0.56 0.5564 1.0 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F16 compound treatment 14035.3 291.0 0.26 0.2631 1.0 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F17 mock treatment 14378.7 635.0 0.57 0.5732 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F18 mock treatment 13853.2 109.0 0.1 0.0986 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F19 compound treatment 14818.2 1070.0 0.97 0.97 1.0 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F20 compound treatment 14246.6 503.0 0.45 0.4539 1.0 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F21 compound treatment 14447.5 704.0 0.64 0.6353 1.0 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F22 compound treatment 14194.1 450.0 0.41 0.4065 1.0 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F23 compound treatment 14632.0 888.0 0.8 0.8019 1.0 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 F24 compound treatment 13854.4 110.0 0.1 0.0997 1.0 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G01 compound treatment 13026.6 -717.0 -0.65 -0.6478 -1.0 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G02 compound treatment 13588.3 -156.0 -0.14 -0.1406 -1.0 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G03 mock treatment 13695.7 -48.3 -0.04 -0.0436 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G04 mock treatment 13056.6 -687.0 -0.62 -0.6207 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G05 compound treatment 15108.2 1360.0 1.23 1.2319 1.0 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G06 compound treatment 14767.1 1020.0 0.92 0.9239 1.0 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G07 compound treatment 14358.0 614.0 0.55 0.5545 1.0 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G08 compound treatment 14041.2 297.0 0.27 0.2684 1.0 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G09 compound treatment 13792.7 48.7 0.04 0.044 1.0 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G10 compound treatment 13678.9 -65.1 -0.06 -0.0588 -1.0 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G11 compound treatment 14022.8 279.0 0.25 0.2518 1.0 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G12 compound treatment 13839.1 95.1 0.09 0.0859 1.0 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G13 compound treatment 13566.8 -177.0 -0.16 -0.16 -1.0 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G14 compound treatment 13683.6 -60.4 -0.05 -0.0545 -1.0 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G15 compound treatment 14287.5 544.0 0.49 0.4908 1.0 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G16 compound treatment 14544.4 800.0 0.72 0.7228 1.0 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G17 compound treatment 13972.1 228.0 0.21 0.206 1.0 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G18 compound treatment 14491.3 747.0 0.67 0.6748 1.0 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G19 mock treatment 14051.0 307.0 0.28 0.2772 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G20 mock treatment 14216.6 473.0 0.43 0.4268 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G21 compound treatment 14766.2 1020.0 0.92 0.9231 1.0 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G22 compound treatment 13541.2 -203.0 -0.18 -0.1831 -1.0 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G23 compound treatment 13899.4 155.0 0.14 0.1403 1.0 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 G24 compound treatment 14172.8 429.0 0.39 0.3872 1.0 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H01 compound treatment 13538.7 -205.0 -0.19 -0.1854 -1.0 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H02 compound treatment 13924.7 181.0 0.16 0.1632 1.0 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H03 mock treatment 14185.4 441.0 0.4 0.3986 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H04 mock treatment 14154.9 411.0 0.37 0.3711 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H05 compound treatment 14139.8 396.0 0.36 0.3574 1.0 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H06 compound treatment 14481.5 738.0 0.67 0.666 1.0 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H07 compound treatment 14247.8 504.0 0.45 0.4549 1.0 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H08 compound treatment 14740.2 996.0 0.9 0.8996 1.0 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H09 compound treatment 13570.0 -174.0 -0.16 -0.1571 -1.0 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H10 compound treatment 14495.4 751.0 0.68 0.6785 1.0 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H11 compound treatment 14203.4 459.0 0.41 0.4149 1.0 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H13 compound treatment 14107.7 364.0 0.33 0.3284 1.0 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H14 compound treatment 13996.8 253.0 0.23 0.2283 1.0 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H15 compound treatment 14245.8 502.0 0.45 0.4531 1.0 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H16 compound treatment 14597.4 853.0 0.77 0.7706 1.0 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H17 compound treatment 14252.1 508.0 0.46 0.4588 1.0 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H18 compound treatment 14078.7 335.0 0.3 0.3022 1.0 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H19 mock treatment 14570.5 827.0 0.75 0.7463 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H20 mock treatment 14187.3 443.0 0.4 0.4003 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H21 compound treatment 13761.2 17.2 0.02 0.0155 1.0 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H22 compound treatment 13806.1 62.1 0.06 0.0561 1.0 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H23 compound treatment 14157.0 413.0 0.37 0.373 1.0 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 H24 compound treatment 13521.8 -222.0 -0.2 -0.2006 -1.0 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I01 compound treatment 13684.4 -59.6 -0.05 -0.0538 -1.0 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I02 compound treatment 13782.6 38.6 0.03 0.0349 1.0 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I03 compound treatment 13570.0 -174.0 -0.16 -0.1571 -1.0 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I04 compound treatment 14505.6 762.0 0.69 0.6877 1.0 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I05 mock treatment 14361.3 617.0 0.56 0.5574 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I06 mock treatment 14279.6 536.0 0.48 0.4837 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I07 compound treatment 12890.4 -854.0 -0.77 -0.7708 -1.0 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I08 compound treatment 13550.6 -193.0 -0.17 -0.1746 -1.0 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I09 compound treatment 13389.1 -355.0 -0.32 -0.3205 -1.0 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I10 compound treatment 14156.1 412.0 0.37 0.3721 1.0 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I11 compound treatment 13357.5 -386.0 -0.35 -0.349 -1.0 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I12 compound treatment 6376.9 -7370.0 -6.65 -6.6525 -1.0 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I13 compound treatment 13148.4 -596.0 -0.54 -0.5378 -1.0 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I14 compound treatment 14248.7 505.0 0.46 0.4558 1.0 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I15 compound treatment 14195.8 452.0 0.41 0.408 1.0 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I16 compound treatment 14268.9 525.0 0.47 0.474 1.0 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I17 compound treatment 13788.3 44.3 0.04 0.04 1.0 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I18 compound treatment 13854.8 111.0 0.1 0.1001 1.0 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I19 compound treatment 14401.7 658.0 0.59 0.5939 1.0 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I20 compound treatment 14607.4 863.0 0.78 0.7797 1.0 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I21 mock treatment 13917.5 174.0 0.16 0.1567 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I22 mock treatment 13992.2 248.0 0.22 0.2241 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I23 compound treatment 13659.0 -85.0 -0.08 -0.0767 -1.0 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 I24 compound treatment 12889.5 -854.0 -0.77 -0.7716 -1.0 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J01 compound treatment 13870.6 127.0 0.11 0.1143 1.0 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J02 compound treatment 13666.2 -77.8 -0.07 -0.0702 -1.0 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J03 compound treatment 14042.7 299.0 0.27 0.2697 1.0 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J04 compound treatment 14228.1 484.0 0.44 0.4372 1.0 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J05 mock treatment 13630.0 -114.0 -0.1 -0.1029 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J06 mock treatment 14379.0 635.0 0.57 0.5734 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J07 compound treatment 13520.0 -224.0 -0.2 -0.2023 -1.0 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J08 compound treatment 14162.9 419.0 0.38 0.3783 1.0 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J09 compound treatment 13757.4 13.4 0.01 0.0121 1.0 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J10 compound treatment 14262.2 518.0 0.47 0.4679 1.0 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J11 compound treatment 13640.7 -103.0 -0.09 -0.0933 -1.0 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J12 compound treatment 13892.8 149.0 0.13 0.1344 1.0 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J13 compound treatment 13875.3 131.0 0.12 0.1186 1.0 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J14 compound treatment 13693.2 -50.8 -0.05 -0.0459 -1.0 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J15 compound treatment 13823.1 79.1 0.07 0.0714 1.0 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J16 compound treatment 14450.5 707.0 0.64 0.638 1.0 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J17 compound treatment 14315.1 571.0 0.52 0.5157 1.0 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J18 compound treatment 13885.8 142.0 0.13 0.1281 1.0 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J19 compound treatment 13814.7 70.7 0.06 0.0639 1.0 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J20 compound treatment 14129.3 385.0 0.35 0.3479 1.0 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J21 mock treatment 14256.2 512.0 0.46 0.4625 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J22 mock treatment 14384.1 640.0 0.58 0.578 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J23 compound treatment 14123.4 379.0 0.34 0.3426 1.0 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 J24 compound treatment 13699.2 -44.8 -0.04 -0.0404 -1.0 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K01 compound treatment 13943.5 200.0 0.18 0.1802 1.0 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K02 compound treatment 13437.0 -307.0 -0.28 -0.2772 -1.0 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K03 compound treatment 13041.4 -703.0 -0.63 -0.6344 -1.0 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K04 compound treatment 13325.2 -419.0 -0.38 -0.3782 -1.0 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K05 compound treatment 14301.8 558.0 0.5 0.5037 1.0 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K06 compound treatment 14089.7 346.0 0.31 0.3122 1.0 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K07 mock treatment 13129.8 -614.0 -0.55 -0.5546 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K08 mock treatment 13474.6 -269.0 -0.24 -0.2433 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K09 compound treatment 13564.9 -179.0 -0.16 -0.1617 -1.0 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K10 compound treatment 13247.1 -497.0 -0.45 -0.4487 -1.0 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K11 compound treatment 12874.7 -869.0 -0.78 -0.785 -1.0 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K12 compound treatment 13472.6 -271.0 -0.25 -0.2451 -1.0 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K13 compound treatment 13804.2 60.2 0.05 0.0544 1.0 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K14 compound treatment 13891.5 148.0 0.13 0.1332 1.0 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K15 mock treatment 14213.8 470.0 0.42 0.4242 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K16 mock treatment 12938.3 -806.0 -0.73 -0.7275 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K17 compound treatment 13872.8 129.0 0.12 0.1163 1.0 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K18 compound treatment 14286.7 543.0 0.49 0.4901 1.0 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K19 compound treatment 14497.3 753.0 0.68 0.6802 1.0 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K20 compound treatment 13889.8 146.0 0.13 0.1317 1.0 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K21 compound treatment 14322.1 578.0 0.52 0.522 1.0 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K22 compound treatment 13352.8 -391.0 -0.35 -0.3532 -1.0 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K23 mock treatment 13825.1 81.1 0.07 0.0732 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 K24 mock treatment 13154.4 -590.0 -0.53 -0.5324 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L01 compound treatment 13892.6 149.0 0.13 0.1342 1.0 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L02 compound treatment 13936.7 193.0 0.17 0.174 1.0 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L03 compound treatment 13830.9 86.9 0.08 0.0785 1.0 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L04 compound treatment 12838.9 -905.0 -0.82 -0.8173 -1.0 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L05 compound treatment 14028.8 285.0 0.26 0.2572 1.0 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L06 compound treatment 13048.0 -696.0 -0.63 -0.6285 -1.0 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L07 mock treatment 12782.8 -961.0 -0.87 -0.868 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L08 mock treatment 14537.0 793.0 0.72 0.7161 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L09 compound treatment 13444.7 -299.0 -0.27 -0.2703 -1.0 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L10 compound treatment 13720.6 -23.4 -0.02 -0.0211 -1.0 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L11 compound treatment 13478.0 -266.0 -0.24 -0.2402 -1.0 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L12 compound treatment 13719.1 -24.9 -0.02 -0.0225 -1.0 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L13 compound treatment 13980.8 237.0 0.21 0.2138 1.0 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L14 compound treatment 14175.7 432.0 0.39 0.3898 1.0 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L15 mock treatment 13996.4 252.0 0.23 0.2279 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L16 mock treatment 13585.8 -158.0 -0.14 -0.1428 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L17 compound treatment 14542.7 799.0 0.72 0.7212 1.0 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L18 compound treatment 13943.1 199.0 0.18 0.1798 1.0 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L19 compound treatment 14298.6 555.0 0.5 0.5008 1.0 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L20 compound treatment 14186.2 442.0 0.4 0.3993 1.0 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L21 compound treatment 14846.4 1100.0 1.0 0.9955 1.0 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L22 compound treatment 14193.1 449.0 0.41 0.4056 1.0 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L23 mock treatment 13942.7 199.0 0.18 0.1794 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 L24 mock treatment 13430.2 -314.0 -0.28 -0.2834 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M01 compound treatment 13517.4 -227.0 -0.2 -0.2046 -1.0 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M02 compound treatment 13222.7 -521.0 -0.47 -0.4707 -1.0 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M03 compound treatment 13388.5 -355.0 -0.32 -0.321 -1.0 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M04 compound treatment 13810.4 66.4 0.06 0.06 1.0 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M05 compound treatment 14494.1 750.0 0.68 0.6774 1.0 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M06 compound treatment 13711.4 -32.6 -0.03 -0.0294 -1.0 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M07 compound treatment 14319.4 575.0 0.52 0.5196 1.0 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M08 compound treatment 13966.2 222.0 0.2 0.2007 1.0 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M09 mock treatment 13733.3 -10.7 -0.01 -0.0097 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M10 mock treatment 13263.5 -480.0 -0.43 -0.4339 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M11 compound treatment 13211.0 -533.0 -0.48 -0.4813 -1.0 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M12 compound treatment 13487.7 -256.0 -0.23 -0.2314 -1.0 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M13 mock treatment 13592.1 -152.0 -0.14 -0.1372 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M14 mock treatment 13879.7 136.0 0.12 0.1225 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M15 compound treatment 13728.7 -15.3 -0.01 -0.0138 -1.0 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M16 compound treatment 14009.8 266.0 0.24 0.24 1.0 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M17 compound treatment 14226.8 483.0 0.44 0.436 1.0 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M18 compound treatment 14005.5 262.0 0.24 0.2361 1.0 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M19 compound treatment 14763.0 1020.0 0.92 0.9202 1.0 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M20 compound treatment 14447.1 703.0 0.63 0.6349 1.0 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M21 compound treatment 14416.5 673.0 0.61 0.6073 1.0 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M22 compound treatment 14449.2 705.0 0.64 0.6368 1.0 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M23 compound treatment 14020.3 276.0 0.25 0.2495 1.0 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 M24 compound treatment 14381.4 637.0 0.58 0.5756 1.0 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N01 compound treatment 14008.3 264.0 0.24 0.2387 1.0 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N02 compound treatment 13018.1 -726.0 -0.66 -0.6555 -1.0 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N03 compound treatment 13802.1 58.1 0.05 0.0525 1.0 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N04 compound treatment 13269.8 -474.0 -0.43 -0.4282 -1.0 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N05 compound treatment 13699.9 -44.1 -0.04 -0.0398 -1.0 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N06 compound treatment 13566.9 -177.0 -0.16 -0.1599 -1.0 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N07 compound treatment 13551.7 -192.0 -0.17 -0.1736 -1.0 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N08 compound treatment 13649.7 -94.3 -0.09 -0.0851 -1.0 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N09 mock treatment 13795.1 51.1 0.05 0.0462 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N10 mock treatment 13693.1 -50.9 -0.05 -0.046 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N11 compound treatment 13373.0 -371.0 -0.34 -0.335 -1.0 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N12 compound treatment 13886.8 143.0 0.13 0.129 1.0 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N13 mock treatment 13518.6 -225.0 -0.2 -0.2035 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N14 mock treatment 13312.7 -431.0 -0.39 -0.3895 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N15 compound treatment 13781.1 37.1 0.03 0.0335 1.0 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N16 compound treatment 13620.9 -123.0 -0.11 -0.1111 -1.0 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N17 compound treatment 14199.8 456.0 0.41 0.4116 1.0 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N18 compound treatment 13849.3 105.0 0.1 0.0951 1.0 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N19 compound treatment 14533.6 790.0 0.71 0.713 1.0 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N20 compound treatment 14233.9 490.0 0.44 0.4424 1.0 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N21 compound treatment 14595.8 852.0 0.77 0.7692 1.0 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N22 compound treatment 13993.0 249.0 0.22 0.2249 1.0 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N23 compound treatment 13818.6 74.6 0.07 0.0674 1.0 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 N24 compound treatment 14059.9 316.0 0.29 0.2853 1.0 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O01 compound treatment 13292.5 -451.0 -0.41 -0.4077 -1.0 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O02 compound treatment 13320.6 -423.0 -0.38 -0.3823 -1.0 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O03 compound treatment 14602.3 858.0 0.78 0.7751 1.0 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O04 compound treatment 13260.8 -483.0 -0.44 -0.4363 -1.0 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O05 compound treatment 15150.8 1410.0 1.27 1.2704 1.0 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O06 compound treatment 13415.3 -329.0 -0.3 -0.2968 -1.0 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O07 compound treatment 14414.6 671.0 0.61 0.6056 1.0 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O08 compound treatment 13955.6 212.0 0.19 0.1911 1.0 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O09 compound treatment 13701.2 -42.8 -0.04 -0.0386 -1.0 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O10 compound treatment 12799.0 -945.0 -0.85 -0.8533 -1.0 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O11 mock treatment 12746.9 -997.0 -0.9 -0.9004 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O12 mock treatment 12888.9 -855.0 -0.77 -0.7722 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O13 compound treatment 13257.1 -487.0 -0.44 -0.4397 -1.0 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O14 compound treatment 12865.6 -878.0 -0.79 -0.7932 -1.0 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O15 compound treatment 13019.8 -724.0 -0.65 -0.6539 -1.0 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O16 compound treatment 13789.5 45.5 0.04 0.0411 1.0 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O17 compound treatment 14360.7 617.0 0.56 0.5569 1.0 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O18 compound treatment 14210.8 467.0 0.42 0.4215 1.0 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O19 compound treatment 14623.1 879.0 0.79 0.7938 1.0 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O20 compound treatment 14031.2 287.0 0.26 0.2594 1.0 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O21 compound treatment 14522.6 779.0 0.7 0.7031 1.0 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O22 compound treatment 14203.3 459.0 0.41 0.4148 1.0 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O23 compound treatment 14072.3 328.0 0.3 0.2965 1.0 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 O24 compound treatment 11492.9 -2250.0 -2.03 -2.0327 -1.0 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P01 compound treatment 12474.6 -1270.0 -1.15 -1.1463 -1.0 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P02 compound treatment 12593.7 -1150.0 -1.04 -1.0387 -1.0 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P03 compound treatment 13599.8 -144.0 -0.13 -0.1302 -1.0 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P04 compound treatment 12775.1 -969.0 -0.87 -0.8749 -1.0 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P05 compound treatment 14054.9 311.0 0.28 0.2808 1.0 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P06 compound treatment 11394.8 -2350.0 -2.12 -2.1213 -1.0 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P07 compound treatment 13471.0 -273.0 -0.25 -0.2465 -1.0 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P08 compound treatment 13923.7 180.0 0.16 0.1623 1.0 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P09 compound treatment 14135.5 392.0 0.35 0.3535 1.0 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P10 compound treatment 13849.7 106.0 0.1 0.0955 1.0 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P11 mock treatment 12766.6 -977.0 -0.88 -0.8826 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P12 mock treatment 12804.0 -940.0 -0.85 -0.8488 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P13 compound treatment 13013.7 -730.0 -0.66 -0.6595 -1.0 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P14 compound treatment 12961.2 -783.0 -0.71 -0.7069 -1.0 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P15 compound treatment 14601.3 857.0 0.77 0.7742 1.0 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P16 compound treatment 13539.7 -204.0 -0.18 -0.1845 -1.0 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P17 compound treatment 14620.9 877.0 0.79 0.7919 1.0 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P18 compound treatment 13381.4 -363.0 -0.33 -0.3274 -1.0 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P19 compound treatment 14683.5 940.0 0.85 0.8484 1.0 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P20 compound treatment 13250.8 -493.0 -0.45 -0.4454 -1.0 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P21 compound treatment 13421.7 -322.0 -0.29 -0.291 -1.0 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P22 compound treatment 13299.0 -445.0 -0.4 -0.4018 -1.0 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P23 compound treatment 13567.0 -177.0 -0.16 -0.1598 -1.0 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2096 P24 compound treatment 12933.1 -811.0 -0.73 -0.7322 -1.0 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A01 compound treatment 13006.8 -837.0 -0.76 -0.7559 -1.0 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A02 compound treatment 12630.2 -1210.0 -1.1 -1.096 -1.0 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A03 compound treatment 14146.4 303.0 0.27 0.2732 1.0 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A04 compound treatment 13430.2 -414.0 -0.37 -0.3736 -1.0 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A05 compound treatment 14503.0 659.0 0.6 0.5952 1.0 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A06 compound treatment 13865.7 21.8 0.02 0.0197 1.0 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A07 compound treatment 14177.6 334.0 0.3 0.3013 1.0 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A08 compound treatment 13386.2 -458.0 -0.41 -0.4133 -1.0 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A09 compound treatment 14733.2 889.0 0.8 0.8031 1.0 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A10 compound treatment 13543.5 -300.0 -0.27 -0.2712 -1.0 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A11 compound treatment 14027.9 184.0 0.17 0.1662 1.0 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A12 compound treatment 13122.8 -721.0 -0.65 -0.6511 -1.0 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A13 mock treatment 14526.9 683.0 0.62 0.6168 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A14 mock treatment 13222.5 -621.0 -0.56 -0.5611 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A15 compound treatment 14723.2 879.0 0.79 0.794 1.0 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A16 compound treatment 13794.4 -49.5 -0.04 -0.0447 -1.0 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A17 compound treatment 14551.4 708.0 0.64 0.6389 1.0 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A18 compound treatment 14065.8 222.0 0.2 0.2004 1.0 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A19 compound treatment 15507.8 1660.0 1.5 1.5025 1.0 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A20 compound treatment 13108.7 -735.0 -0.66 -0.6639 -1.0 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A21 compound treatment 14997.1 1150.0 1.04 1.0414 1.0 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A22 compound treatment 13387.1 -457.0 -0.41 -0.4125 -1.0 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A23 compound treatment 13596.5 -247.0 -0.22 -0.2234 -1.0 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 A24 compound treatment 12090.8 -1750.0 -1.58 -1.583 -1.0 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B01 compound treatment 13037.8 -806.0 -0.73 -0.7279 -1.0 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B02 compound treatment 13798.7 -45.2 -0.04 -0.0408 -1.0 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B03 compound treatment 14522.2 678.0 0.61 0.6125 1.0 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B04 compound treatment 14825.2 981.0 0.89 0.8861 1.0 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B05 compound treatment 14279.4 436.0 0.39 0.3933 1.0 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B06 compound treatment 14567.3 723.0 0.65 0.6532 1.0 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B07 compound treatment 13863.3 19.4 0.02 0.0175 1.0 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B08 compound treatment 13351.5 -492.0 -0.44 -0.4446 -1.0 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B09 compound treatment 14067.6 224.0 0.2 0.202 1.0 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B10 compound treatment 13740.4 -103.0 -0.09 -0.0934 -1.0 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B11 compound treatment 14046.3 202.0 0.18 0.1828 1.0 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B12 compound treatment 13610.3 -234.0 -0.21 -0.2109 -1.0 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B13 mock treatment 13559.3 -285.0 -0.26 -0.257 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B14 mock treatment 13957.1 113.0 0.1 0.1022 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B15 compound treatment 14038.0 194.0 0.18 0.1753 1.0 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B16 compound treatment 13758.0 -85.9 -0.08 -0.0776 -1.0 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B17 compound treatment 14720.6 877.0 0.79 0.7917 1.0 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B18 compound treatment 14084.4 241.0 0.22 0.2172 1.0 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B19 compound treatment 14584.4 741.0 0.67 0.6687 1.0 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B20 compound treatment 14741.2 897.0 0.81 0.8103 1.0 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B21 compound treatment 14758.2 914.0 0.83 0.8256 1.0 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B22 compound treatment 14383.2 539.0 0.49 0.487 1.0 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B23 compound treatment 14285.2 441.0 0.4 0.3985 1.0 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 B24 compound treatment 13455.9 -388.0 -0.35 -0.3504 -1.0 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C01 compound treatment 13525.7 -318.0 -0.29 -0.2873 -1.0 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C02 compound treatment 14108.6 265.0 0.24 0.239 1.0 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C03 compound treatment 13963.7 120.0 0.11 0.1082 1.0 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C04 compound treatment 14353.5 510.0 0.46 0.4602 1.0 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C05 compound treatment 14525.0 681.0 0.62 0.6151 1.0 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C06 compound treatment 13892.6 48.7 0.04 0.044 1.0 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C07 compound treatment 13273.4 -570.0 -0.52 -0.5152 -1.0 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C08 compound treatment 13418.0 -426.0 -0.38 -0.3846 -1.0 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C09 compound treatment 14051.6 208.0 0.19 0.1876 1.0 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C10 compound treatment 13123.0 -721.0 -0.65 -0.651 -1.0 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C11 mock treatment 13953.8 110.0 0.1 0.0993 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C12 mock treatment 13283.0 -561.0 -0.51 -0.5065 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C13 compound treatment 13992.6 149.0 0.13 0.1343 1.0 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C14 compound treatment 13100.2 -744.0 -0.67 -0.6716 -1.0 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C15 mock treatment 13821.5 -22.4 -0.02 -0.0202 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C16 mock treatment 13745.9 -98.0 -0.09 -0.0885 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C17 compound treatment 14397.3 553.0 0.5 0.4997 1.0 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C18 compound treatment 13933.4 89.5 0.08 0.0808 1.0 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C19 compound treatment 14607.8 764.0 0.69 0.6898 1.0 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C20 compound treatment 14458.2 614.0 0.55 0.5547 1.0 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C21 compound treatment 15164.2 1320.0 1.19 1.1923 1.0 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C22 compound treatment 14234.0 390.0 0.35 0.3523 1.0 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C23 compound treatment 14388.9 545.0 0.49 0.4922 1.0 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 C24 compound treatment 13617.1 -227.0 -0.2 -0.2048 -1.0 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D01 compound treatment 13783.9 -60.0 -0.05 -0.0542 -1.0 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D02 compound treatment 13966.3 122.0 0.11 0.1105 1.0 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D03 compound treatment 14503.1 659.0 0.6 0.5953 1.0 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D04 compound treatment 14125.5 282.0 0.25 0.2543 1.0 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D05 compound treatment 14521.7 678.0 0.61 0.6121 1.0 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D06 compound treatment 13646.8 -197.0 -0.18 -0.178 -1.0 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D07 compound treatment 13432.2 -412.0 -0.37 -0.3718 -1.0 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D08 compound treatment 13976.4 133.0 0.12 0.1197 1.0 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D09 compound treatment 14227.0 383.0 0.35 0.346 1.0 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D10 compound treatment 13224.8 -619.0 -0.56 -0.559 -1.0 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D11 mock treatment 13748.6 -95.3 -0.09 -0.086 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D12 mock treatment 13893.9 50.0 0.05 0.0452 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D13 compound treatment 13858.5 14.6 0.01 0.0132 1.0 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D14 compound treatment 13812.0 -31.9 -0.03 -0.0288 -1.0 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D15 mock treatment 14873.6 1030.0 0.93 0.9298 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D16 mock treatment 13869.5 25.6 0.02 0.0231 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D17 compound treatment 14546.1 702.0 0.63 0.6341 1.0 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D18 compound treatment 13879.4 35.5 0.03 0.0321 1.0 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D19 compound treatment 15000.0 1160.0 1.04 1.044 1.0 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D20 compound treatment 14452.5 609.0 0.55 0.5496 1.0 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D21 compound treatment 14798.1 954.0 0.86 0.8617 1.0 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D22 compound treatment 14309.2 465.0 0.42 0.4202 1.0 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D23 compound treatment 14489.3 645.0 0.58 0.5828 1.0 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 D24 compound treatment 13916.2 72.3 0.07 0.0653 1.0 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E01 mock treatment 13619.7 -224.0 -0.2 -0.2024 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E02 mock treatment 13483.9 -360.0 -0.33 -0.3251 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E03 compound treatment 13959.7 116.0 0.1 0.1046 1.0 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E04 compound treatment 13836.0 -7.88 -0.01 -0.0071 -1.0 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E05 compound treatment 14130.6 287.0 0.26 0.2589 1.0 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E06 compound treatment 13783.0 -60.9 -0.05 -0.055 -1.0 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E07 compound treatment 13824.9 -19.0 -0.02 -0.0171 -1.0 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E08 compound treatment 13550.1 -294.0 -0.27 -0.2653 -1.0 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E09 mock treatment 13527.3 -317.0 -0.29 -0.2859 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E10 mock treatment 13817.1 -26.8 -0.02 -0.0242 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E11 compound treatment 13880.3 36.4 0.03 0.0329 1.0 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E12 compound treatment 12257.3 -1590.0 -1.43 -1.4327 -1.0 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E13 compound treatment 13945.1 101.0 0.09 0.0914 1.0 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E14 compound treatment 13200.4 -643.0 -0.58 -0.5811 -1.0 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E15 compound treatment 12850.4 -993.0 -0.9 -0.8971 -1.0 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E16 compound treatment 13459.0 -385.0 -0.35 -0.3476 -1.0 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E17 mock treatment 14023.9 180.0 0.16 0.1626 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E18 mock treatment 13430.3 -414.0 -0.37 -0.3735 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E19 compound treatment 14343.0 499.0 0.45 0.4507 1.0 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E20 compound treatment 14058.0 214.0 0.19 0.1933 1.0 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E21 compound treatment 14130.4 287.0 0.26 0.2587 1.0 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E22 compound treatment 14269.8 426.0 0.38 0.3846 1.0 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E23 compound treatment 14086.6 243.0 0.22 0.2192 1.0 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 E24 compound treatment 13492.3 -352.0 -0.32 -0.3175 -1.0 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F01 mock treatment 14235.9 392.0 0.35 0.354 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F02 mock treatment 13862.5 18.6 0.02 0.0168 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F03 compound treatment 14241.5 398.0 0.36 0.359 1.0 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F04 compound treatment 14178.0 334.0 0.3 0.3017 1.0 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F05 compound treatment 13968.5 125.0 0.11 0.1125 1.0 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F06 compound treatment 14227.8 384.0 0.35 0.3467 1.0 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F07 compound treatment 14150.4 307.0 0.28 0.2768 1.0 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F08 compound treatment 13760.9 -83.0 -0.07 -0.0749 -1.0 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F09 mock treatment 13944.6 101.0 0.09 0.0909 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F10 mock treatment 13379.5 -464.0 -0.42 -0.4193 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F11 compound treatment 14146.7 303.0 0.27 0.2734 1.0 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F12 compound treatment 13426.8 -417.0 -0.38 -0.3766 -1.0 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F13 compound treatment 12471.1 -1370.0 -1.24 -1.2396 -1.0 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F14 compound treatment 13549.7 -294.0 -0.27 -0.2657 -1.0 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F15 compound treatment 14825.0 981.0 0.89 0.886 1.0 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F16 compound treatment 13746.7 -97.2 -0.09 -0.0878 -1.0 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F17 mock treatment 14352.3 508.0 0.46 0.4591 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F18 mock treatment 14162.8 319.0 0.29 0.288 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F19 compound treatment 14309.6 466.0 0.42 0.4205 1.0 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F20 compound treatment 14408.6 565.0 0.51 0.5099 1.0 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F21 compound treatment 15457.7 1610.0 1.46 1.4573 1.0 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F22 compound treatment 14462.8 619.0 0.56 0.5589 1.0 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F23 compound treatment 14265.6 422.0 0.38 0.3808 1.0 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 F24 compound treatment 13422.7 -421.0 -0.38 -0.3803 -1.0 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G01 compound treatment 13389.5 -454.0 -0.41 -0.4103 -1.0 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G02 compound treatment 13819.2 -24.7 -0.02 -0.0223 -1.0 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G03 mock treatment 14164.6 321.0 0.29 0.2896 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G04 mock treatment 14147.5 304.0 0.27 0.2742 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G05 compound treatment 14597.0 753.0 0.68 0.6801 1.0 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G06 compound treatment 14210.7 367.0 0.33 0.3312 1.0 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G07 compound treatment 14129.8 286.0 0.26 0.2582 1.0 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G08 compound treatment 13780.7 -63.2 -0.06 -0.0571 -1.0 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G09 compound treatment 13573.8 -270.0 -0.24 -0.2439 -1.0 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G10 compound treatment 13531.9 -312.0 -0.28 -0.2817 -1.0 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G11 compound treatment 13591.8 -252.0 -0.23 -0.2276 -1.0 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G12 compound treatment 13805.4 -38.5 -0.03 -0.0348 -1.0 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G13 compound treatment 13500.3 -344.0 -0.31 -0.3103 -1.0 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G14 compound treatment 13592.5 -251.0 -0.23 -0.227 -1.0 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G15 compound treatment 13844.6 0.716 0.0 6.0E-4 1.0 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G16 compound treatment 13897.5 53.6 0.05 0.0484 1.0 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G17 compound treatment 13609.1 -235.0 -0.21 -0.212 -1.0 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G18 compound treatment 14427.8 584.0 0.53 0.5273 1.0 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G19 mock treatment 14626.3 782.0 0.71 0.7065 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G20 mock treatment 14591.8 748.0 0.68 0.6754 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G21 compound treatment 14742.9 899.0 0.81 0.8118 1.0 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G22 compound treatment 14337.3 493.0 0.45 0.4456 1.0 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G23 compound treatment 14587.0 743.0 0.67 0.671 1.0 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 G24 compound treatment 13142.8 -701.0 -0.63 -0.6331 -1.0 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H01 compound treatment 13769.0 -74.9 -0.07 -0.0676 -1.0 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H02 compound treatment 14424.1 580.0 0.52 0.5239 1.0 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H03 mock treatment 14377.7 534.0 0.48 0.482 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H04 mock treatment 14100.4 257.0 0.23 0.2316 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H05 compound treatment 14563.8 720.0 0.65 0.6501 1.0 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H06 compound treatment 14291.5 448.0 0.4 0.4042 1.0 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H07 compound treatment 14018.9 175.0 0.16 0.158 1.0 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H08 compound treatment 13833.6 -10.3 -0.01 -0.0093 -1.0 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H09 compound treatment 13492.6 -351.0 -0.32 -0.3172 -1.0 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H10 compound treatment 13673.6 -170.0 -0.15 -0.1538 -1.0 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H11 compound treatment 14444.3 600.0 0.54 0.5422 1.0 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H12 compound treatment 13654.7 -189.0 -0.17 -0.1708 -1.0 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H13 compound treatment 13827.5 -16.4 -0.01 -0.0148 -1.0 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H14 compound treatment 14101.3 257.0 0.23 0.2324 1.0 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H15 compound treatment 13835.2 -8.68 -0.01 -0.0078 -1.0 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H16 compound treatment 13490.8 -353.0 -0.32 -0.3188 -1.0 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H17 compound treatment 13974.9 131.0 0.12 0.1183 1.0 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H18 compound treatment 14494.9 651.0 0.59 0.5879 1.0 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H19 mock treatment 13855.2 11.3 0.01 0.0102 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H20 mock treatment 14013.1 169.0 0.15 0.1528 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H21 compound treatment 15049.8 1210.0 1.09 1.089 1.0 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H22 compound treatment 14353.1 509.0 0.46 0.4598 1.0 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H23 compound treatment 14751.2 907.0 0.82 0.8193 1.0 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 H24 compound treatment 13673.6 -170.0 -0.15 -0.1538 -1.0 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I01 compound treatment 13652.4 -191.0 -0.17 -0.1729 -1.0 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I02 compound treatment 13153.0 -691.0 -0.62 -0.6239 -1.0 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I03 compound treatment 13656.0 -188.0 -0.17 -0.1697 -1.0 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I04 compound treatment 14078.5 235.0 0.21 0.2119 1.0 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I05 mock treatment 14124.2 280.0 0.25 0.2531 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I06 mock treatment 13878.7 34.8 0.03 0.0314 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I07 compound treatment 13427.5 -416.0 -0.38 -0.376 -1.0 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I08 compound treatment 13387.6 -456.0 -0.41 -0.412 -1.0 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I09 compound treatment 13326.2 -518.0 -0.47 -0.4675 -1.0 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I10 compound treatment 13151.7 -692.0 -0.63 -0.625 -1.0 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I11 compound treatment 12915.7 -928.0 -0.84 -0.8382 -1.0 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I12 compound treatment 13518.6 -325.0 -0.29 -0.2937 -1.0 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I13 compound treatment 13637.1 -207.0 -0.19 -0.1867 -1.0 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I14 compound treatment 13601.9 -242.0 -0.22 -0.2185 -1.0 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I15 compound treatment 13693.2 -151.0 -0.14 -0.1361 -1.0 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I16 compound treatment 13624.2 -220.0 -0.2 -0.1984 -1.0 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I17 compound treatment 13492.6 -351.0 -0.32 -0.3172 -1.0 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I18 compound treatment 13719.6 -124.0 -0.11 -0.1122 -1.0 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I19 compound treatment 14581.5 738.0 0.67 0.6661 1.0 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I20 compound treatment 14360.6 517.0 0.47 0.4666 1.0 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I21 mock treatment 14341.9 498.0 0.45 0.4497 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I22 mock treatment 13993.3 149.0 0.13 0.1349 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I23 compound treatment 14295.0 451.0 0.41 0.4074 1.0 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 I24 compound treatment 13372.6 -471.0 -0.43 -0.4256 -1.0 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J01 compound treatment 13666.1 -178.0 -0.16 -0.1605 -1.0 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J02 compound treatment 14028.4 185.0 0.17 0.1666 1.0 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J03 compound treatment 14862.8 1020.0 0.92 0.9201 1.0 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J04 compound treatment 14313.9 470.0 0.42 0.4244 1.0 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J05 mock treatment 14151.2 307.0 0.28 0.2775 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J06 mock treatment 14024.0 180.0 0.16 0.1626 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J07 compound treatment 12641.8 -1200.0 -1.09 -1.0855 -1.0 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J08 compound treatment 13951.6 108.0 0.1 0.0973 1.0 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J09 compound treatment 14039.8 196.0 0.18 0.1769 1.0 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J10 compound treatment 13512.9 -331.0 -0.3 -0.2989 -1.0 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J11 compound treatment 14180.6 337.0 0.3 0.3041 1.0 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J12 compound treatment 13263.3 -581.0 -0.52 -0.5243 -1.0 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J13 compound treatment 13508.7 -335.0 -0.3 -0.3027 -1.0 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J14 compound treatment 13605.4 -238.0 -0.22 -0.2154 -1.0 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J15 compound treatment 13546.3 -298.0 -0.27 -0.2687 -1.0 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J16 compound treatment 13904.0 60.1 0.05 0.0543 1.0 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J17 compound treatment 14487.4 644.0 0.58 0.5811 1.0 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J18 compound treatment 14020.0 176.0 0.16 0.159 1.0 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J19 compound treatment 13933.8 89.9 0.08 0.0812 1.0 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J20 compound treatment 14441.2 597.0 0.54 0.5394 1.0 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J21 mock treatment 14521.6 678.0 0.61 0.612 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J22 mock treatment 14076.1 232.0 0.21 0.2097 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J23 compound treatment 14247.5 404.0 0.36 0.3645 1.0 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 J24 compound treatment 13185.4 -658.0 -0.59 -0.5946 -1.0 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K01 compound treatment 13210.3 -634.0 -0.57 -0.5721 -1.0 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K02 compound treatment 13908.1 64.2 0.06 0.058 1.0 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K03 compound treatment 14081.0 237.0 0.21 0.2141 1.0 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K04 compound treatment 14003.4 160.0 0.14 0.144 1.0 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K05 compound treatment 14151.6 308.0 0.28 0.2779 1.0 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K06 compound treatment 14178.2 334.0 0.3 0.3019 1.0 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K07 mock treatment 13542.5 -301.0 -0.27 -0.2722 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K08 mock treatment 13392.8 -451.0 -0.41 -0.4073 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K09 compound treatment 13332.6 -511.0 -0.46 -0.4617 -1.0 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K10 compound treatment 13810.7 -33.2 -0.03 -0.03 -1.0 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K11 compound treatment 12719.0 -1120.0 -1.02 -1.0158 -1.0 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K12 compound treatment 13903.2 59.3 0.05 0.0536 1.0 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K13 compound treatment 13816.3 -27.6 -0.02 -0.0249 -1.0 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K14 compound treatment 13531.2 -313.0 -0.28 -0.2824 -1.0 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K15 mock treatment 14081.5 238.0 0.21 0.2146 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K16 mock treatment 13724.4 -119.0 -0.11 -0.1079 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K17 compound treatment 13514.0 -330.0 -0.3 -0.2979 -1.0 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K18 compound treatment 14071.5 228.0 0.21 0.2055 1.0 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K19 compound treatment 14369.2 525.0 0.47 0.4744 1.0 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K20 compound treatment 14557.3 713.0 0.64 0.6442 1.0 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K21 compound treatment 14543.3 699.0 0.63 0.6316 1.0 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K22 compound treatment 13874.2 30.3 0.03 0.0274 1.0 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K23 mock treatment 13796.6 -47.3 -0.04 -0.0427 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 K24 mock treatment 13274.1 -570.0 -0.51 -0.5145 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L01 compound treatment 13409.4 -434.0 -0.39 -0.3923 -1.0 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L02 compound treatment 14179.2 335.0 0.3 0.3028 1.0 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L03 compound treatment 14124.2 280.0 0.25 0.2531 1.0 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L04 compound treatment 13945.7 102.0 0.09 0.0919 1.0 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L05 compound treatment 14821.4 978.0 0.88 0.8827 1.0 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L06 compound treatment 13883.5 39.6 0.04 0.0358 1.0 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L07 mock treatment 14263.7 420.0 0.38 0.3791 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L08 mock treatment 13985.4 142.0 0.13 0.1278 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L09 compound treatment 13223.6 -620.0 -0.56 -0.5601 -1.0 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L10 compound treatment 13474.0 -370.0 -0.33 -0.334 -1.0 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L11 compound treatment 13625.3 -219.0 -0.2 -0.1974 -1.0 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L12 compound treatment 13596.8 -247.0 -0.22 -0.2231 -1.0 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L13 compound treatment 13556.7 -287.0 -0.26 -0.2593 -1.0 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L14 compound treatment 13570.7 -273.0 -0.25 -0.2467 -1.0 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L15 mock treatment 13954.0 110.0 0.1 0.0994 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L16 mock treatment 13804.9 -39.0 -0.04 -0.0352 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L17 compound treatment 13891.3 47.4 0.04 0.0428 1.0 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L18 compound treatment 13780.3 -63.6 -0.06 -0.0574 -1.0 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L19 compound treatment 14505.7 662.0 0.6 0.5976 1.0 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L20 compound treatment 13634.3 -210.0 -0.19 -0.1893 -1.0 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L21 compound treatment 14091.5 248.0 0.22 0.2236 1.0 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L22 compound treatment 13254.9 -589.0 -0.53 -0.5319 -1.0 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L23 mock treatment 14414.6 571.0 0.52 0.5154 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 L24 mock treatment 13499.5 -344.0 -0.31 -0.311 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M01 compound treatment 13014.7 -829.0 -0.75 -0.7488 -1.0 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M02 compound treatment 12999.3 -845.0 -0.76 -0.7627 -1.0 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M03 compound treatment 14159.1 315.0 0.28 0.2846 1.0 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M04 compound treatment 13552.2 -292.0 -0.26 -0.2634 -1.0 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M05 compound treatment 13693.8 -150.0 -0.14 -0.1355 -1.0 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M06 compound treatment 13147.9 -696.0 -0.63 -0.6285 -1.0 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M07 compound treatment 12891.0 -953.0 -0.86 -0.8605 -1.0 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M08 compound treatment 13603.3 -241.0 -0.22 -0.2172 -1.0 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M09 mock treatment 13093.1 -751.0 -0.68 -0.678 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M10 mock treatment 12966.5 -877.0 -0.79 -0.7923 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M11 compound treatment 13510.9 -333.0 -0.3 -0.3007 -1.0 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M12 compound treatment 13656.3 -188.0 -0.17 -0.1694 -1.0 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M13 mock treatment 13677.5 -166.0 -0.15 -0.1502 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M14 mock treatment 13346.5 -497.0 -0.45 -0.4491 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M15 compound treatment 13539.9 -304.0 -0.27 -0.2745 -1.0 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M16 compound treatment 13528.6 -315.0 -0.28 -0.2847 -1.0 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M17 compound treatment 13969.6 126.0 0.11 0.1135 1.0 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M18 compound treatment 13778.1 -65.8 -0.06 -0.0594 -1.0 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M19 compound treatment 13691.7 -152.0 -0.14 -0.1374 -1.0 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M20 compound treatment 12518.8 -1330.0 -1.2 -1.1966 -1.0 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M21 compound treatment 14315.5 472.0 0.43 0.4259 1.0 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M22 compound treatment 13266.2 -578.0 -0.52 -0.5217 -1.0 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M23 compound treatment 13910.8 66.9 0.06 0.0604 1.0 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 M24 compound treatment 13576.3 -268.0 -0.24 -0.2416 -1.0 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N01 compound treatment 12965.7 -878.0 -0.79 -0.793 -1.0 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N02 compound treatment 13144.0 -700.0 -0.63 -0.632 -1.0 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N03 compound treatment 17087.4 3240.0 2.93 2.9289 1.0 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N04 compound treatment 13636.8 -207.0 -0.19 -0.187 -1.0 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N05 compound treatment 13275.6 -568.0 -0.51 -0.5132 -1.0 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N06 compound treatment 13872.2 28.3 0.03 0.0256 1.0 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N07 compound treatment 13881.3 37.4 0.03 0.0338 1.0 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N08 compound treatment 13897.7 53.8 0.05 0.0486 1.0 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N09 mock treatment 13083.3 -761.0 -0.69 -0.6868 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N10 mock treatment 13859.2 15.3 0.01 0.0138 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N11 compound treatment 12934.9 -909.0 -0.82 -0.8208 -1.0 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N12 compound treatment 14101.4 258.0 0.23 0.2325 1.0 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N13 mock treatment 13624.3 -220.0 -0.2 -0.1983 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N14 mock treatment 13875.0 31.1 0.03 0.0281 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N15 compound treatment 13560.6 -283.0 -0.26 -0.2558 -1.0 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N16 compound treatment 13986.3 142.0 0.13 0.1286 1.0 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N17 compound treatment 14150.8 307.0 0.28 0.2771 1.0 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N18 compound treatment 13117.8 -726.0 -0.66 -0.6557 -1.0 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N19 compound treatment 13826.2 -17.7 -0.02 -0.016 -1.0 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N20 compound treatment 13826.4 -17.5 -0.02 -0.0158 -1.0 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N21 compound treatment 14322.6 479.0 0.43 0.4323 1.0 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N22 compound treatment 14267.0 423.0 0.38 0.3821 1.0 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N23 compound treatment 13732.4 -111.0 -0.1 -0.1007 -1.0 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 N24 compound treatment 13085.0 -759.0 -0.69 -0.6853 -1.0 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O01 compound treatment 12920.1 -924.0 -0.83 -0.8342 -1.0 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O02 compound treatment 12323.1 -1520.0 -1.37 -1.3733 -1.0 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O03 compound treatment 13535.2 -309.0 -0.28 -0.2787 -1.0 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O04 compound treatment 12536.9 -1310.0 -1.18 -1.1802 -1.0 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O05 compound treatment 13076.8 -767.0 -0.69 -0.6927 -1.0 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O06 compound treatment 13344.3 -500.0 -0.45 -0.4511 -1.0 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O07 compound treatment 12654.3 -1190.0 -1.07 -1.0742 -1.0 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O08 compound treatment 12871.5 -972.0 -0.88 -0.8781 -1.0 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O09 compound treatment 13274.5 -569.0 -0.51 -0.5142 -1.0 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O10 compound treatment 12953.9 -890.0 -0.8 -0.8037 -1.0 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O11 mock treatment 12848.8 -995.0 -0.9 -0.8986 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O12 mock treatment 13492.2 -352.0 -0.32 -0.3176 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O13 compound treatment 13689.9 -154.0 -0.14 -0.139 -1.0 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O14 compound treatment 13231.0 -613.0 -0.55 -0.5534 -1.0 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O15 compound treatment 13798.0 -45.9 -0.04 -0.0414 -1.0 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O16 compound treatment 12978.8 -865.0 -0.78 -0.7812 -1.0 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O17 compound treatment 13492.4 -351.0 -0.32 -0.3174 -1.0 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O18 compound treatment 13441.5 -402.0 -0.36 -0.3634 -1.0 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O19 compound treatment 14193.0 349.0 0.32 0.3153 1.0 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O20 compound treatment 13528.8 -315.0 -0.28 -0.2845 -1.0 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O21 compound treatment 14327.0 483.0 0.44 0.4363 1.0 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O22 compound treatment 14061.4 218.0 0.2 0.1964 1.0 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O23 compound treatment 13788.5 -55.4 -0.05 -0.05 -1.0 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 O24 compound treatment 13980.8 137.0 0.12 0.1236 1.0 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P01 compound treatment 13508.0 -336.0 -0.3 -0.3033 -1.0 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P02 compound treatment 12929.5 -914.0 -0.83 -0.8257 -1.0 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P03 compound treatment 13889.3 45.4 0.04 0.041 1.0 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P04 compound treatment 13324.5 -519.0 -0.47 -0.469 -1.0 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P05 compound treatment 13247.6 -596.0 -0.54 -0.5384 -1.0 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P06 compound treatment 12811.3 -1030.0 -0.93 -0.9324 -1.0 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P07 compound treatment 13083.6 -760.0 -0.69 -0.6865 -1.0 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P08 compound treatment 13130.3 -714.0 -0.64 -0.6444 -1.0 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P09 compound treatment 13587.3 -257.0 -0.23 -0.2317 -1.0 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P10 compound treatment 13358.8 -485.0 -0.44 -0.438 -1.0 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P11 mock treatment 13333.0 -511.0 -0.46 -0.4613 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P12 mock treatment 13792.2 -51.7 -0.05 -0.0467 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P13 compound treatment 14301.6 458.0 0.41 0.4133 1.0 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P14 compound treatment 13629.4 -214.0 -0.19 -0.1937 -1.0 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P15 compound treatment 13742.4 -101.0 -0.09 -0.0916 -1.0 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P16 compound treatment 13232.5 -611.0 -0.55 -0.5521 -1.0 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P17 compound treatment 13334.4 -509.0 -0.46 -0.4601 -1.0 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P18 compound treatment 13370.3 -474.0 -0.43 -0.4277 -1.0 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P19 compound treatment 14432.3 588.0 0.53 0.5313 1.0 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P20 compound treatment 14327.7 484.0 0.44 0.4369 1.0 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P21 compound treatment 14161.6 318.0 0.29 0.2869 1.0 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P22 compound treatment 13500.6 -343.0 -0.31 -0.31 -1.0 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P23 compound treatment 14151.1 307.0 0.28 0.2774 1.0 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2097 P24 compound treatment 13337.4 -506.0 -0.46 -0.4574 -1.0 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A01 compound treatment 13152.2 -235.0 -0.21 -0.2119 -1.0 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A02 compound treatment 12860.8 -526.0 -0.48 -0.475 -1.0 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A03 compound treatment 13127.7 -259.0 -0.23 -0.234 -1.0 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A04 compound treatment 13303.3 -83.6 -0.08 -0.0755 -1.0 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A05 compound treatment 13900.7 514.0 0.46 0.464 1.0 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A06 compound treatment 13516.0 129.0 0.12 0.1166 1.0 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A07 compound treatment 13179.7 -207.0 -0.19 -0.1871 -1.0 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A08 compound treatment 13260.2 -127.0 -0.11 -0.1144 -1.0 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A09 compound treatment 13494.7 108.0 0.1 0.0974 1.0 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A10 compound treatment 12791.9 -595.0 -0.54 -0.5373 -1.0 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A11 compound treatment 13580.4 194.0 0.17 0.1748 1.0 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A12 compound treatment 13430.3 43.4 0.04 0.0392 1.0 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A13 mock treatment 13813.6 427.0 0.39 0.3853 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A14 mock treatment 13208.0 -179.0 -0.16 -0.1615 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A15 compound treatment 14054.6 668.0 0.6 0.603 1.0 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A16 compound treatment 13778.6 392.0 0.35 0.3537 1.0 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A17 compound treatment 13266.6 -120.0 -0.11 -0.1086 -1.0 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A18 compound treatment 13471.5 84.6 0.08 0.0764 1.0 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A19 compound treatment 14768.8 1380.0 1.25 1.2479 1.0 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A20 compound treatment 13656.2 269.0 0.24 0.2432 1.0 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A21 compound treatment 13119.0 -268.0 -0.24 -0.2419 -1.0 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A22 compound treatment 12563.4 -823.0 -0.74 -0.7436 -1.0 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A23 compound treatment 13761.0 374.0 0.34 0.3378 1.0 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 A24 compound treatment 13427.2 40.3 0.04 0.0364 1.0 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B01 compound treatment 13202.0 -185.0 -0.17 -0.1669 -1.0 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B02 compound treatment 12575.5 -811.0 -0.73 -0.7327 -1.0 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B03 compound treatment 12280.7 -1110.0 -1.0 -0.9989 -1.0 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B04 compound treatment 13009.0 -378.0 -0.34 -0.3412 -1.0 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B05 compound treatment 12980.0 -407.0 -0.37 -0.3674 -1.0 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B06 compound treatment 13652.1 265.0 0.24 0.2395 1.0 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B07 compound treatment 13654.9 268.0 0.24 0.242 1.0 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B08 compound treatment 13336.6 -50.3 -0.05 -0.0454 -1.0 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B09 compound treatment 13173.1 -214.0 -0.19 -0.193 -1.0 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B10 compound treatment 13396.5 9.64 0.01 0.0087 1.0 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B11 compound treatment 13693.7 307.0 0.28 0.2771 1.0 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B12 compound treatment 13544.8 158.0 0.14 0.1426 1.0 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B13 mock treatment 13406.8 19.9 0.02 0.018 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B14 mock treatment 13710.7 324.0 0.29 0.2924 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B15 compound treatment 13632.3 245.0 0.22 0.2216 1.0 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B16 compound treatment 13235.1 -152.0 -0.14 -0.137 -1.0 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B17 compound treatment 13717.3 330.0 0.3 0.2984 1.0 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B18 compound treatment 13355.7 -31.2 -0.03 -0.0281 -1.0 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B19 compound treatment 13912.7 526.0 0.47 0.4748 1.0 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B20 compound treatment 13711.9 325.0 0.29 0.2935 1.0 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B21 compound treatment 13613.3 226.0 0.2 0.2045 1.0 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B22 compound treatment 13175.0 -212.0 -0.19 -0.1913 -1.0 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B23 compound treatment 13650.8 264.0 0.24 0.2383 1.0 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 B24 compound treatment 13323.1 -63.8 -0.06 -0.0576 -1.0 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C01 compound treatment 13047.1 -340.0 -0.31 -0.3068 -1.0 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C02 compound treatment 12871.2 -516.0 -0.47 -0.4656 -1.0 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C03 compound treatment 12667.6 -719.0 -0.65 -0.6495 -1.0 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C04 compound treatment 12911.2 -476.0 -0.43 -0.4295 -1.0 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C05 compound treatment 13208.3 -179.0 -0.16 -0.1612 -1.0 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C06 compound treatment 13353.3 -33.6 -0.03 -0.0303 -1.0 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C07 compound treatment 12607.3 -780.0 -0.7 -0.704 -1.0 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C08 compound treatment 13131.8 -255.0 -0.23 -0.2303 -1.0 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C09 compound treatment 13256.0 -131.0 -0.12 -0.1182 -1.0 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C10 compound treatment 12877.8 -509.0 -0.46 -0.4597 -1.0 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C11 mock treatment 12836.8 -550.0 -0.5 -0.4967 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C12 mock treatment 13340.1 -46.8 -0.04 -0.0422 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C13 compound treatment 13705.7 319.0 0.29 0.2879 1.0 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C14 compound treatment 13288.0 -98.9 -0.09 -0.0893 -1.0 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C15 mock treatment 13470.4 83.5 0.08 0.0754 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C16 mock treatment 13128.7 -258.0 -0.23 -0.2331 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C17 compound treatment 13768.7 382.0 0.34 0.3448 1.0 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C18 compound treatment 12970.7 -416.0 -0.38 -0.3758 -1.0 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C19 compound treatment 14007.8 621.0 0.56 0.5607 1.0 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C20 compound treatment 13797.9 411.0 0.37 0.3712 1.0 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C21 compound treatment 13914.8 528.0 0.48 0.4767 1.0 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C22 compound treatment 13266.8 -120.0 -0.11 -0.1084 -1.0 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C23 compound treatment 13856.3 469.0 0.42 0.4239 1.0 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 C24 compound treatment 13481.0 94.1 0.09 0.085 1.0 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D01 compound treatment 13716.4 330.0 0.3 0.2976 1.0 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D02 compound treatment 13096.3 -291.0 -0.26 -0.2624 -1.0 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D03 compound treatment 14436.9 1050.0 0.95 0.9482 1.0 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D04 compound treatment 13274.0 -113.0 -0.1 -0.1019 -1.0 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D05 compound treatment 14108.1 721.0 0.65 0.6513 1.0 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D06 compound treatment 13712.5 326.0 0.29 0.2941 1.0 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D07 compound treatment 13111.0 -276.0 -0.25 -0.2491 -1.0 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D08 compound treatment 13526.4 140.0 0.13 0.126 1.0 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D09 compound treatment 13560.8 174.0 0.16 0.1571 1.0 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D10 compound treatment 13149.1 -238.0 -0.21 -0.2147 -1.0 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D11 mock treatment 12913.9 -473.0 -0.43 -0.4271 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D12 mock treatment 13557.8 171.0 0.15 0.1544 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D13 compound treatment 13630.4 244.0 0.22 0.2199 1.0 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D14 compound treatment 13532.9 146.0 0.13 0.1319 1.0 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D15 mock treatment 13759.3 372.0 0.34 0.3363 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D16 mock treatment 13325.1 -61.8 -0.06 -0.0558 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D17 compound treatment 14472.3 1090.0 0.98 0.9802 1.0 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D18 compound treatment 12906.4 -480.0 -0.43 -0.4339 -1.0 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D19 compound treatment 13882.9 496.0 0.45 0.4479 1.0 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D20 compound treatment 13988.5 602.0 0.54 0.5433 1.0 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D21 compound treatment 14278.1 891.0 0.8 0.8048 1.0 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D22 compound treatment 13240.2 -147.0 -0.13 -0.1324 -1.0 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D23 compound treatment 13880.8 494.0 0.45 0.446 1.0 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 D24 compound treatment 13766.8 380.0 0.34 0.3431 1.0 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E01 mock treatment 13141.8 -245.0 -0.22 -0.2213 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E02 mock treatment 12892.3 -495.0 -0.45 -0.4466 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E03 compound treatment 13162.2 -225.0 -0.2 -0.2029 -1.0 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E04 compound treatment 13211.7 -175.0 -0.16 -0.1582 -1.0 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E05 compound treatment 13560.7 174.0 0.16 0.157 1.0 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E06 compound treatment 13686.1 299.0 0.27 0.2702 1.0 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E07 compound treatment 12914.9 -472.0 -0.43 -0.4262 -1.0 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E08 compound treatment 13090.1 -297.0 -0.27 -0.268 -1.0 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E09 mock treatment 12819.5 -567.0 -0.51 -0.5123 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E10 mock treatment 12641.7 -745.0 -0.67 -0.6729 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E11 compound treatment 13676.1 289.0 0.26 0.2612 1.0 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E12 compound treatment 13811.6 425.0 0.38 0.3835 1.0 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E13 compound treatment 13802.6 416.0 0.38 0.3754 1.0 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E14 compound treatment 13630.9 244.0 0.22 0.2204 1.0 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E15 compound treatment 13961.0 574.0 0.52 0.5184 1.0 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E16 compound treatment 13315.3 -71.6 -0.06 -0.0646 -1.0 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E17 mock treatment 13387.3 0.436 0.0 4.0E-4 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E18 mock treatment 13804.8 418.0 0.38 0.3774 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E19 compound treatment 12568.3 -819.0 -0.74 -0.7392 -1.0 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E20 compound treatment 13659.0 272.0 0.25 0.2457 1.0 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E21 compound treatment 13601.1 214.0 0.19 0.1935 1.0 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E22 compound treatment 13504.7 118.0 0.11 0.1064 1.0 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E23 compound treatment 14356.9 970.0 0.88 0.8759 1.0 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 E24 compound treatment 13688.3 301.0 0.27 0.2722 1.0 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F01 mock treatment 13553.2 166.0 0.15 0.1502 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F02 mock treatment 12747.6 -639.0 -0.58 -0.5773 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F03 compound treatment 13662.2 275.0 0.25 0.2486 1.0 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F04 compound treatment 13887.7 501.0 0.45 0.4523 1.0 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F05 compound treatment 13792.8 406.0 0.37 0.3666 1.0 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F06 compound treatment 13784.0 397.0 0.36 0.3586 1.0 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F07 compound treatment 13856.8 470.0 0.42 0.4244 1.0 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F08 compound treatment 13848.1 461.0 0.42 0.4165 1.0 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F09 mock treatment 13959.6 573.0 0.52 0.5172 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F10 mock treatment 13559.4 173.0 0.16 0.1558 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F11 compound treatment 13869.8 483.0 0.44 0.4361 1.0 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F12 compound treatment 13728.9 342.0 0.31 0.3089 1.0 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F13 compound treatment 13425.5 38.6 0.03 0.0349 1.0 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F14 compound treatment 13469.4 82.5 0.07 0.0745 1.0 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F15 compound treatment 13933.9 547.0 0.49 0.494 1.0 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F16 compound treatment 13553.4 167.0 0.15 0.1504 1.0 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F17 mock treatment 14187.3 800.0 0.72 0.7228 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F18 mock treatment 13769.0 382.0 0.35 0.3451 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F19 compound treatment 15012.7 1630.0 1.47 1.4681 1.0 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F20 compound treatment 13098.4 -288.0 -0.26 -0.2605 -1.0 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F21 compound treatment 14638.3 1250.0 1.13 1.1301 1.0 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F22 compound treatment 12614.9 -772.0 -0.7 -0.6971 -1.0 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F23 compound treatment 14485.9 1100.0 0.99 0.9924 1.0 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 F24 compound treatment 13200.3 -187.0 -0.17 -0.1685 -1.0 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G01 compound treatment 13463.5 76.6 0.07 0.0692 1.0 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G02 compound treatment 13189.7 -197.0 -0.18 -0.178 -1.0 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G03 mock treatment 13061.1 -326.0 -0.29 -0.2942 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G04 mock treatment 13525.2 138.0 0.12 0.1249 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G05 compound treatment 14408.8 1020.0 0.92 0.9228 1.0 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G06 compound treatment 13787.2 400.0 0.36 0.3615 1.0 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G07 compound treatment 13362.9 -24.0 -0.02 -0.0216 -1.0 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G08 compound treatment 13508.0 121.0 0.11 0.1094 1.0 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G09 compound treatment 13227.1 -160.0 -0.14 -0.1443 -1.0 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G10 compound treatment 13175.3 -212.0 -0.19 -0.191 -1.0 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G11 compound treatment 13114.4 -272.0 -0.25 -0.246 -1.0 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G12 compound treatment 13489.5 103.0 0.09 0.0927 1.0 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G13 compound treatment 14003.9 617.0 0.56 0.5572 1.0 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G14 compound treatment 13619.2 232.0 0.21 0.2098 1.0 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G15 compound treatment 13931.5 545.0 0.49 0.4918 1.0 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G16 compound treatment 14007.7 621.0 0.56 0.5606 1.0 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G17 compound treatment 14467.8 1080.0 0.98 0.9761 1.0 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G18 compound treatment 13528.8 142.0 0.13 0.1282 1.0 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G19 mock treatment 14065.4 679.0 0.61 0.6127 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G20 mock treatment 13870.7 484.0 0.44 0.4369 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G21 compound treatment 14369.5 983.0 0.89 0.8873 1.0 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G22 compound treatment 13925.8 539.0 0.49 0.4867 1.0 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G23 compound treatment 14183.8 797.0 0.72 0.7196 1.0 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 G24 compound treatment 13097.4 -289.0 -0.26 -0.2614 -1.0 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H01 compound treatment 13675.5 289.0 0.26 0.2606 1.0 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H02 compound treatment 13107.3 -280.0 -0.25 -0.2524 -1.0 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H03 mock treatment 13953.3 566.0 0.51 0.5115 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H04 mock treatment 12936.1 -451.0 -0.41 -0.407 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H05 compound treatment 13941.7 555.0 0.5 0.501 1.0 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H06 compound treatment 14157.6 771.0 0.7 0.696 1.0 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H07 compound treatment 14085.4 699.0 0.63 0.6308 1.0 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H08 compound treatment 13955.7 569.0 0.51 0.5137 1.0 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H09 compound treatment 13340.5 -46.4 -0.04 -0.0419 -1.0 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H10 compound treatment 13913.7 527.0 0.48 0.4757 1.0 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H11 compound treatment 13399.6 12.7 0.01 0.0115 1.0 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H12 compound treatment 13660.7 274.0 0.25 0.2473 1.0 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H13 compound treatment 13301.2 -85.7 -0.08 -0.0774 -1.0 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H14 compound treatment 13927.9 541.0 0.49 0.4886 1.0 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H15 compound treatment 14057.7 671.0 0.61 0.6058 1.0 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H16 compound treatment 14037.2 650.0 0.59 0.5873 1.0 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H17 compound treatment 14024.9 638.0 0.58 0.5762 1.0 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H18 compound treatment 14351.7 965.0 0.87 0.8713 1.0 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H19 mock treatment 13893.3 506.0 0.46 0.4573 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H20 mock treatment 14165.5 779.0 0.7 0.7031 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H21 compound treatment 14497.9 1110.0 1.0 1.0033 1.0 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H22 compound treatment 14660.5 1270.0 1.15 1.1501 1.0 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H23 compound treatment 13304.4 -82.5 -0.07 -0.0745 -1.0 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 H24 compound treatment 14019.8 633.0 0.57 0.5715 1.0 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I01 compound treatment 12927.5 -459.0 -0.41 -0.4148 -1.0 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I02 compound treatment 13371.9 -15.0 -0.01 -0.0135 -1.0 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I03 compound treatment 12925.6 -461.0 -0.42 -0.4165 -1.0 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I04 compound treatment 13065.4 -321.0 -0.29 -0.2903 -1.0 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I05 mock treatment 13559.6 173.0 0.16 0.156 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I06 mock treatment 13704.5 318.0 0.29 0.2868 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I07 compound treatment 12825.6 -561.0 -0.51 -0.5068 -1.0 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I08 compound treatment 13213.4 -173.0 -0.16 -0.1566 -1.0 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I09 compound treatment 13123.5 -263.0 -0.24 -0.2378 -1.0 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I10 compound treatment 13356.4 -30.5 -0.03 -0.0275 -1.0 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I11 compound treatment 12975.1 -412.0 -0.37 -0.3718 -1.0 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I12 compound treatment 12993.3 -394.0 -0.36 -0.3554 -1.0 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I13 compound treatment 13498.8 112.0 0.1 0.1011 1.0 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I14 compound treatment 13642.7 256.0 0.23 0.231 1.0 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I15 compound treatment 13426.8 39.9 0.04 0.0361 1.0 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I16 compound treatment 14190.9 804.0 0.73 0.7261 1.0 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I17 compound treatment 13491.0 104.0 0.09 0.094 1.0 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I18 compound treatment 13659.7 273.0 0.25 0.2464 1.0 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I19 compound treatment 13700.8 314.0 0.28 0.2835 1.0 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I20 compound treatment 13596.2 209.0 0.19 0.189 1.0 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I21 mock treatment 13677.1 290.0 0.26 0.2621 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I22 mock treatment 13491.9 105.0 0.09 0.0948 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I23 compound treatment 14027.8 641.0 0.58 0.5788 1.0 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 I24 compound treatment 13298.3 -88.6 -0.08 -0.08 -1.0 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J01 compound treatment 12960.1 -427.0 -0.39 -0.3854 -1.0 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J02 compound treatment 13115.8 -271.0 -0.24 -0.2448 -1.0 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J03 compound treatment 12876.8 -510.0 -0.46 -0.4606 -1.0 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J04 compound treatment 13355.5 -31.4 -0.03 -0.0283 -1.0 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J05 mock treatment 12653.1 -734.0 -0.66 -0.6626 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J06 mock treatment 12625.4 -761.0 -0.69 -0.6876 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J07 compound treatment 13348.6 -38.3 -0.03 -0.0346 -1.0 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J08 compound treatment 13866.2 479.0 0.43 0.4328 1.0 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J09 compound treatment 12695.1 -692.0 -0.62 -0.6247 -1.0 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J10 compound treatment 13197.7 -189.0 -0.17 -0.1708 -1.0 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J11 compound treatment 13352.3 -34.6 -0.03 -0.0312 -1.0 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J12 compound treatment 13314.5 -72.4 -0.07 -0.0653 -1.0 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J13 compound treatment 13174.4 -212.0 -0.19 -0.1919 -1.0 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J14 compound treatment 13581.9 195.0 0.18 0.1761 1.0 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J15 compound treatment 13193.5 -193.0 -0.17 -0.1746 -1.0 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J16 compound treatment 13784.5 398.0 0.36 0.3591 1.0 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J17 compound treatment 12266.7 -1120.0 -1.01 -1.0115 -1.0 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J18 compound treatment 13680.8 294.0 0.27 0.2654 1.0 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J19 compound treatment 13864.2 477.0 0.43 0.431 1.0 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J20 compound treatment 14189.2 802.0 0.72 0.7245 1.0 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J21 mock treatment 13740.3 353.0 0.32 0.3192 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J22 mock treatment 13542.6 156.0 0.14 0.1406 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J23 compound treatment 14154.3 767.0 0.69 0.693 1.0 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 J24 compound treatment 13866.9 480.0 0.43 0.4335 1.0 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K01 compound treatment 13154.5 -232.0 -0.21 -0.2098 -1.0 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K02 compound treatment 12749.4 -637.0 -0.58 -0.5756 -1.0 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K03 compound treatment 12877.8 -509.0 -0.46 -0.4597 -1.0 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K04 compound treatment 12768.4 -618.0 -0.56 -0.5585 -1.0 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K05 compound treatment 13374.4 -12.5 -0.01 -0.0113 -1.0 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K06 compound treatment 13182.6 -204.0 -0.18 -0.1845 -1.0 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K07 mock treatment 12845.7 -541.0 -0.49 -0.4887 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K08 mock treatment 12952.1 -435.0 -0.39 -0.3926 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K09 compound treatment 12640.7 -746.0 -0.67 -0.6738 -1.0 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K10 compound treatment 12455.5 -931.0 -0.84 -0.841 -1.0 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K11 compound treatment 12273.7 -1110.0 -1.01 -1.0052 -1.0 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K12 compound treatment 13456.5 69.6 0.06 0.0629 1.0 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K13 compound treatment 13177.0 -210.0 -0.19 -0.1895 -1.0 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K14 compound treatment 13911.4 525.0 0.47 0.4737 1.0 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K15 mock treatment 13645.8 259.0 0.23 0.2338 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K16 mock treatment 13586.7 200.0 0.18 0.1805 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K17 compound treatment 13097.0 -290.0 -0.26 -0.2617 -1.0 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K18 compound treatment 13525.6 139.0 0.13 0.1253 1.0 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K19 compound treatment 12801.1 -586.0 -0.53 -0.5289 -1.0 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K20 compound treatment 13657.6 271.0 0.24 0.2445 1.0 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K21 compound treatment 13219.6 -167.0 -0.15 -0.151 -1.0 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K22 compound treatment 13279.3 -108.0 -0.1 -0.0971 -1.0 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K23 mock treatment 13666.9 280.0 0.25 0.2529 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 K24 mock treatment 13316.9 -70.0 -0.06 -0.0632 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L01 compound treatment 12790.5 -596.0 -0.54 -0.5385 -1.0 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L02 compound treatment 13096.3 -291.0 -0.26 -0.2624 -1.0 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L03 compound treatment 13125.0 -262.0 -0.24 -0.2365 -1.0 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L04 compound treatment 13595.5 209.0 0.19 0.1884 1.0 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L05 compound treatment 13944.8 558.0 0.5 0.5038 1.0 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L06 compound treatment 13696.6 310.0 0.28 0.2797 1.0 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L07 mock treatment 13796.0 409.0 0.37 0.3695 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L08 mock treatment 13420.5 33.6 0.03 0.0304 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L09 compound treatment 12978.4 -408.0 -0.37 -0.3688 -1.0 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L10 compound treatment 14023.0 636.0 0.57 0.5744 1.0 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L11 compound treatment 13176.6 -210.0 -0.19 -0.1899 -1.0 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L12 compound treatment 13473.6 86.7 0.08 0.0783 1.0 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L13 compound treatment 13581.4 195.0 0.18 0.1757 1.0 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L14 compound treatment 13865.2 478.0 0.43 0.4319 1.0 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L15 mock treatment 13513.4 127.0 0.11 0.1143 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L16 mock treatment 13260.1 -127.0 -0.11 -0.1145 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L17 compound treatment 13861.2 474.0 0.43 0.4283 1.0 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L18 compound treatment 14078.2 691.0 0.62 0.6243 1.0 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L19 compound treatment 13636.9 250.0 0.23 0.2258 1.0 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L20 compound treatment 13494.5 108.0 0.1 0.0972 1.0 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L21 compound treatment 14063.2 676.0 0.61 0.6107 1.0 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L22 compound treatment 13798.8 412.0 0.37 0.372 1.0 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L23 mock treatment 13819.2 432.0 0.39 0.3904 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 L24 mock treatment 12629.8 -757.0 -0.68 -0.6836 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M01 compound treatment 12881.6 -505.0 -0.46 -0.4563 -1.0 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M02 compound treatment 12786.2 -601.0 -0.54 -0.5424 -1.0 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M03 compound treatment 12590.9 -796.0 -0.72 -0.7188 -1.0 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M04 compound treatment 12765.3 -622.0 -0.56 -0.5613 -1.0 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M05 compound treatment 13044.9 -342.0 -0.31 -0.3088 -1.0 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M06 compound treatment 13345.1 -41.8 -0.04 -0.0377 -1.0 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M07 compound treatment 12547.4 -839.0 -0.76 -0.758 -1.0 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M08 compound treatment 13000.1 -387.0 -0.35 -0.3493 -1.0 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M09 mock treatment 13184.1 -203.0 -0.18 -0.1831 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M10 mock treatment 13452.4 65.5 0.06 0.0592 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M11 compound treatment 13051.6 -335.0 -0.3 -0.3027 -1.0 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M12 compound treatment 13459.7 72.8 0.07 0.0658 1.0 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M13 mock treatment 13462.8 75.9 0.07 0.0686 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M14 mock treatment 13978.2 591.0 0.53 0.534 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M15 compound treatment 13912.6 526.0 0.47 0.4747 1.0 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M16 compound treatment 13491.3 104.0 0.09 0.0943 1.0 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M17 compound treatment 13541.1 154.0 0.14 0.1393 1.0 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M18 compound treatment 13689.3 302.0 0.27 0.2731 1.0 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M19 compound treatment 13459.1 72.2 0.07 0.0652 1.0 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M20 compound treatment 13588.1 201.0 0.18 0.1817 1.0 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M21 compound treatment 13378.9 -7.96 -0.01 -0.0072 -1.0 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M22 compound treatment 13631.6 245.0 0.22 0.221 1.0 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M23 compound treatment 13384.6 -2.26 0.0 -0.002 -1.0 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 M24 compound treatment 13718.6 332.0 0.3 0.2996 1.0 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N01 compound treatment 12850.8 -536.0 -0.48 -0.4841 -1.0 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N02 compound treatment 12864.7 -522.0 -0.47 -0.4715 -1.0 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N03 compound treatment 13284.2 -103.0 -0.09 -0.0927 -1.0 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N04 compound treatment 12957.6 -429.0 -0.39 -0.3876 -1.0 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N05 compound treatment 13552.8 166.0 0.15 0.1498 1.0 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N06 compound treatment 13132.4 -254.0 -0.23 -0.2298 -1.0 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N07 compound treatment 13454.7 67.8 0.06 0.0613 1.0 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N08 compound treatment 13649.3 262.0 0.24 0.237 1.0 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N09 mock treatment 13636.5 250.0 0.23 0.2254 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N10 mock treatment 13343.5 -43.4 -0.04 -0.0392 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N11 compound treatment 12982.6 -404.0 -0.37 -0.3651 -1.0 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N12 compound treatment 13229.6 -157.0 -0.14 -0.142 -1.0 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N13 mock treatment 12946.0 -441.0 -0.4 -0.3981 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N14 mock treatment 13564.7 178.0 0.16 0.1606 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N15 compound treatment 13591.8 205.0 0.19 0.1851 1.0 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N16 compound treatment 13870.1 483.0 0.44 0.4364 1.0 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N17 compound treatment 13658.1 271.0 0.24 0.2449 1.0 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N18 compound treatment 13226.7 -160.0 -0.14 -0.1446 -1.0 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N19 compound treatment 13281.2 -106.0 -0.1 -0.0954 -1.0 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N20 compound treatment 13823.8 437.0 0.39 0.3946 1.0 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N21 compound treatment 14370.1 983.0 0.89 0.8879 1.0 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N22 compound treatment 13293.5 -93.4 -0.08 -0.0843 -1.0 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N23 compound treatment 13451.9 65.0 0.06 0.0587 1.0 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 N24 compound treatment 13099.2 -288.0 -0.26 -0.2598 -1.0 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O01 compound treatment 12464.2 -923.0 -0.83 -0.8332 -1.0 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O02 compound treatment 12169.6 -1220.0 -1.1 -1.0992 -1.0 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O03 compound treatment 12868.7 -518.0 -0.47 -0.4679 -1.0 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O04 compound treatment 12958.6 -428.0 -0.39 -0.3867 -1.0 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O05 compound treatment 13978.0 591.0 0.53 0.5338 1.0 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O06 compound treatment 12947.8 -439.0 -0.4 -0.3965 -1.0 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O07 compound treatment 13155.4 -231.0 -0.21 -0.209 -1.0 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O08 compound treatment 13031.6 -355.0 -0.32 -0.3208 -1.0 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O09 compound treatment 13395.8 8.94 0.01 0.0081 1.0 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O10 compound treatment 12678.3 -709.0 -0.64 -0.6398 -1.0 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O11 mock treatment 12697.2 -690.0 -0.62 -0.6228 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O12 mock treatment 13258.6 -128.0 -0.12 -0.1158 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O13 compound treatment 13074.4 -312.0 -0.28 -0.2822 -1.0 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O14 compound treatment 12790.7 -596.0 -0.54 -0.5383 -1.0 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O15 compound treatment 13257.7 -129.0 -0.12 -0.1166 -1.0 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O16 compound treatment 13210.5 -176.0 -0.16 -0.1593 -1.0 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O17 compound treatment 13482.2 95.3 0.09 0.0861 1.0 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O18 compound treatment 13159.2 -228.0 -0.21 -0.2056 -1.0 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O19 compound treatment 13272.3 -115.0 -0.1 -0.1035 -1.0 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O20 compound treatment 12531.9 -855.0 -0.77 -0.772 -1.0 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O21 compound treatment 13768.7 382.0 0.34 0.3448 1.0 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O22 compound treatment 13521.9 135.0 0.12 0.1219 1.0 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O23 compound treatment 13078.2 -309.0 -0.28 -0.2787 -1.0 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 O24 compound treatment 12911.8 -475.0 -0.43 -0.429 -1.0 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P01 compound treatment 11650.3 -1740.0 -1.57 -1.5681 -1.0 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P02 compound treatment 11300.8 -2090.0 -1.88 -1.8837 -1.0 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P03 compound treatment 12669.4 -717.0 -0.65 -0.6479 -1.0 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P04 compound treatment 11982.7 -1400.0 -1.27 -1.268 -1.0 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P05 compound treatment 12738.5 -648.0 -0.59 -0.5855 -1.0 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P06 compound treatment 12907.0 -480.0 -0.43 -0.4333 -1.0 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P07 compound treatment 13549.5 163.0 0.15 0.1469 1.0 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P08 compound treatment 13305.1 -81.8 -0.07 -0.0738 -1.0 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P09 compound treatment 13787.1 400.0 0.36 0.3614 1.0 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P10 compound treatment 12764.7 -622.0 -0.56 -0.5618 -1.0 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P11 mock treatment 12683.4 -703.0 -0.64 -0.6352 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P12 mock treatment 12699.0 -688.0 -0.62 -0.6211 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P13 compound treatment 12883.9 -503.0 -0.45 -0.4542 -1.0 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P14 compound treatment 12882.7 -504.0 -0.46 -0.4553 -1.0 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P15 compound treatment 12904.4 -482.0 -0.44 -0.4357 -1.0 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P16 compound treatment 13020.8 -366.0 -0.33 -0.3306 -1.0 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P17 compound treatment 13146.0 -241.0 -0.22 -0.2175 -1.0 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P18 compound treatment 13135.2 -252.0 -0.23 -0.2273 -1.0 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P19 compound treatment 13381.7 -5.16 0.0 -0.0047 -1.0 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P20 compound treatment 12421.0 -966.0 -0.87 -0.8722 -1.0 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P21 compound treatment 12703.5 -683.0 -0.62 -0.6171 -1.0 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P22 compound treatment 12810.6 -576.0 -0.52 -0.5204 -1.0 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P23 compound treatment 12645.9 -741.0 -0.67 -0.6691 -1.0 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.2098 P24 compound treatment 12270.0 -1120.0 -1.01 -1.0085 -1.0 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A01 mock treatment 17240.1 -251.0 -0.23 -0.2264 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A02 mock treatment 17963.6 473.0 0.43 0.4269 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A03 mock treatment 17243.8 -247.0 -0.22 -0.2231 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A04 mock treatment 17696.2 205.0 0.19 0.1855 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A05 mock treatment 17723.3 232.0 0.21 0.2099 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A06 mock treatment 17955.9 465.0 0.42 0.42 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A07 mock treatment 17025.1 -466.0 -0.42 -0.4206 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A08 mock treatment 17499.6 8.77 0.01 0.0079 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A09 mock treatment 17797.6 307.0 0.28 0.277 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A10 mock treatment 16838.6 -652.0 -0.59 -0.589 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A11 mock treatment 17198.0 -293.0 -0.26 -0.2644 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A12 mock treatment 16474.6 -1020.0 -0.92 -0.9177 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A13 mock treatment 16625.2 -866.0 -0.78 -0.7817 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A14 mock treatment 17265.2 -226.0 -0.2 -0.2037 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A15 mock treatment 17418.3 -72.5 -0.07 -0.0655 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A16 mock treatment 18359.7 869.0 0.78 0.7846 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A17 mock treatment 18154.6 664.0 0.6 0.5994 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A18 mock treatment 18295.1 804.0 0.73 0.7263 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A19 mock treatment 18244.3 753.0 0.68 0.6804 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A20 mock treatment 18398.3 907.0 0.82 0.8195 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A21 mock treatment 17907.5 417.0 0.38 0.3763 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A22 mock treatment 17734.1 243.0 0.22 0.2197 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A23 mock treatment 17325.6 -165.0 -0.15 -0.1492 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base A24 mock treatment 16490.6 -1000.0 -0.9 -0.9032 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B01 mock treatment 17390.9 -99.9 -0.09 -0.0902 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B02 mock treatment 17796.2 305.0 0.28 0.2758 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B03 mock treatment 18179.5 689.0 0.62 0.6219 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B04 mock treatment 17745.8 255.0 0.23 0.2302 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B05 mock treatment 17304.0 -187.0 -0.17 -0.1687 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B06 mock treatment 18653.9 1160.0 1.05 1.0503 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B07 mock treatment 16891.6 -599.0 -0.54 -0.5411 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B08 mock treatment 17949.7 459.0 0.41 0.4144 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B09 mock treatment 18196.2 705.0 0.64 0.637 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B10 mock treatment 17132.5 -358.0 -0.32 -0.3236 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B11 mock treatment 17107.3 -384.0 -0.35 -0.3463 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B12 mock treatment 16843.8 -647.0 -0.58 -0.5843 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B13 mock treatment 17393.8 -97.0 -0.09 -0.0876 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B14 mock treatment 17271.0 -220.0 -0.2 -0.1985 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B15 mock treatment 17930.5 440.0 0.4 0.397 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B16 mock treatment 17352.6 -138.0 -0.12 -0.1248 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B17 mock treatment 18148.2 657.0 0.59 0.5936 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B18 mock treatment 17071.9 -419.0 -0.38 -0.3783 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B19 mock treatment 17620.8 130.0 0.12 0.1174 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B20 mock treatment 18100.6 610.0 0.55 0.5506 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B21 mock treatment 18735.2 1240.0 1.12 1.1237 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B22 mock treatment 17754.0 263.0 0.24 0.2376 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B23 mock treatment 18197.7 707.0 0.64 0.6383 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base B24 mock treatment 17369.3 -122.0 -0.11 -0.1097 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C01 mock treatment 17389.9 -101.0 -0.09 -0.0911 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C02 mock treatment 18608.5 1120.0 1.01 1.0093 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C03 mock treatment 17714.4 224.0 0.2 0.2019 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C04 mock treatment 18141.8 651.0 0.59 0.5878 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C05 mock treatment 18836.6 1350.0 1.22 1.2152 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C06 mock treatment 18774.7 1280.0 1.16 1.1593 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C07 mock treatment 17021.1 -470.0 -0.42 -0.4242 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C08 mock treatment 17453.3 -37.5 -0.03 -0.0339 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C09 mock treatment 17777.1 286.0 0.26 0.2585 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C10 mock treatment 16413.2 -1080.0 -0.97 -0.9731 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C11 mock treatment 17503.5 12.7 0.01 0.0114 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C12 mock treatment 17122.1 -369.0 -0.33 -0.333 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C13 mock treatment 17688.6 198.0 0.18 0.1786 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C14 mock treatment 17029.0 -462.0 -0.42 -0.417 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C15 mock treatment 18062.0 571.0 0.52 0.5158 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C16 mock treatment 16429.1 -1060.0 -0.96 -0.9587 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C17 mock treatment 18426.8 936.0 0.85 0.8452 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C18 mock treatment 18141.5 651.0 0.59 0.5876 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C19 mock treatment 18007.2 516.0 0.47 0.4663 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C20 mock treatment 18376.1 885.0 0.8 0.7994 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C21 mock treatment 18006.5 516.0 0.47 0.4657 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C22 mock treatment 16445.2 -1050.0 -0.94 -0.9442 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C23 mock treatment 17966.7 476.0 0.43 0.4297 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base C24 mock treatment 17090.9 -400.0 -0.36 -0.3611 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D01 mock treatment 17986.5 496.0 0.45 0.4476 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D02 mock treatment 18009.8 519.0 0.47 0.4686 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D03 mock treatment 18119.1 628.0 0.57 0.5673 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D04 mock treatment 18001.2 510.0 0.46 0.4609 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D05 mock treatment 18951.2 1460.0 1.32 1.3187 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D06 mock treatment 18460.3 969.0 0.88 0.8754 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D07 mock treatment 17881.8 391.0 0.35 0.353 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D08 mock treatment 18106.8 616.0 0.56 0.5562 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D09 mock treatment 17725.9 235.0 0.21 0.2123 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D10 mock treatment 17699.0 208.0 0.19 0.188 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D11 mock treatment 17439.3 -51.5 -0.05 -0.0465 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D12 mock treatment 16008.6 -1480.0 -1.34 -1.3385 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D13 mock treatment 17997.5 507.0 0.46 0.4575 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D14 mock treatment 17401.5 -89.3 -0.08 -0.0807 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D15 mock treatment 18662.9 1170.0 1.06 1.0584 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D16 mock treatment 17368.4 -122.0 -0.11 -0.1106 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D17 mock treatment 18353.7 863.0 0.78 0.7792 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D18 mock treatment 17437.3 -53.5 -0.05 -0.0483 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D19 mock treatment 18407.4 917.0 0.83 0.8277 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D20 mock treatment 18069.4 579.0 0.52 0.5225 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D21 mock treatment 18464.6 974.0 0.88 0.8793 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D22 mock treatment 18004.8 514.0 0.46 0.4641 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D23 mock treatment 18127.5 637.0 0.57 0.5749 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base D24 mock treatment 17156.6 -334.0 -0.3 -0.3018 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E01 mock treatment 17217.0 -274.0 -0.25 -0.2473 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E02 mock treatment 16945.6 -545.0 -0.49 -0.4923 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E03 mock treatment 17230.0 -261.0 -0.24 -0.2355 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E04 mock treatment 18110.9 620.0 0.56 0.5599 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E05 mock treatment 16507.0 -984.0 -0.89 -0.8884 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E06 mock treatment 17880.5 390.0 0.35 0.3519 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E07 mock treatment 17540.0 49.2 0.04 0.0444 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E08 mock treatment 17843.7 353.0 0.32 0.3186 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E09 mock treatment 17642.2 151.0 0.14 0.1367 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E10 mock treatment 17400.4 -90.4 -0.08 -0.0817 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E11 mock treatment 18002.7 512.0 0.46 0.4622 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E12 mock treatment 17213.6 -277.0 -0.25 -0.2503 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E13 mock treatment 17939.4 449.0 0.41 0.4051 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E14 mock treatment 18356.4 866.0 0.78 0.7816 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E15 mock treatment 18560.5 1070.0 0.97 0.9659 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E16 mock treatment 17411.8 -79.0 -0.07 -0.0714 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E17 mock treatment 17763.8 273.0 0.25 0.2465 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E18 mock treatment 17640.7 150.0 0.14 0.1353 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E19 mock treatment 18704.1 1210.0 1.1 1.0956 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E20 mock treatment 16087.7 -1400.0 -1.27 -1.267 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E21 mock treatment 18192.9 702.0 0.63 0.634 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E22 mock treatment 17942.1 451.0 0.41 0.4075 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E23 mock treatment 17448.8 -42.0 -0.04 -0.038 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base E24 mock treatment 16521.8 -969.0 -0.88 -0.875 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F01 mock treatment 16339.4 -1150.0 -1.04 -1.0397 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F02 mock treatment 18380.9 890.0 0.8 0.8037 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F03 mock treatment 18186.6 696.0 0.63 0.6283 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F04 mock treatment 18346.5 856.0 0.77 0.7727 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F05 mock treatment 17925.1 434.0 0.39 0.3922 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F06 mock treatment 17729.6 239.0 0.22 0.2156 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F07 mock treatment 17118.2 -373.0 -0.34 -0.3365 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F08 mock treatment 18327.5 837.0 0.76 0.7555 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F09 mock treatment 17621.7 131.0 0.12 0.1182 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F10 mock treatment 18277.7 787.0 0.71 0.7106 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F11 mock treatment 18102.9 612.0 0.55 0.5527 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F12 mock treatment 17280.0 -211.0 -0.19 -0.1904 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F13 mock treatment 17887.9 397.0 0.36 0.3586 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F14 mock treatment 18482.4 992.0 0.9 0.8954 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F15 mock treatment 16722.5 -768.0 -0.69 -0.6938 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F16 mock treatment 17926.6 436.0 0.39 0.3935 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F17 mock treatment 17975.7 485.0 0.44 0.4378 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F18 mock treatment 17310.2 -181.0 -0.16 -0.1631 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F19 mock treatment 18222.2 731.0 0.66 0.6604 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F20 mock treatment 18266.5 776.0 0.7 0.7004 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F21 mock treatment 18771.2 1280.0 1.16 1.1562 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F22 mock treatment 16287.6 -1200.0 -1.09 -1.0865 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F23 mock treatment 17933.5 443.0 0.4 0.3997 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base F24 mock treatment 17657.9 167.0 0.15 0.1509 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G01 mock treatment 17403.4 -87.4 -0.08 -0.0789 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G02 mock treatment 15613.8 -1880.0 -1.69 -1.695 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G03 mock treatment 17391.8 -99.0 -0.09 -0.0894 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G04 mock treatment 17995.8 505.0 0.46 0.456 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G05 mock treatment 18079.9 589.0 0.53 0.5319 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G06 mock treatment 18413.8 923.0 0.83 0.8335 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G07 mock treatment 17606.5 116.0 0.1 0.1045 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G08 mock treatment 17687.6 197.0 0.18 0.1777 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G09 mock treatment 16844.9 -646.0 -0.58 -0.5833 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G10 mock treatment 17659.0 168.0 0.15 0.1519 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G11 mock treatment 17192.3 -299.0 -0.27 -0.2696 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G12 mock treatment 17482.2 -8.63 -0.01 -0.0078 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G13 mock treatment 17480.2 -10.6 -0.01 -0.0096 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G14 mock treatment 17868.1 377.0 0.34 0.3407 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G15 mock treatment 17647.0 156.0 0.14 0.141 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G16 mock treatment 17450.9 -39.9 -0.04 -0.0361 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G17 mock treatment 17587.7 96.9 0.09 0.0875 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G18 mock treatment 17878.0 387.0 0.35 0.3496 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G19 mock treatment 16389.8 -1100.0 -0.99 -0.9942 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G20 mock treatment 17806.5 316.0 0.29 0.2851 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G21 mock treatment 18544.8 1050.0 0.95 0.9517 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G22 mock treatment 18542.0 1050.0 0.95 0.9492 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G23 mock treatment 17631.0 140.0 0.13 0.1266 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base G24 mock treatment 16861.2 -630.0 -0.57 -0.5686 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H01 mock treatment 17074.0 -417.0 -0.38 -0.3764 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H02 mock treatment 18541.2 1050.0 0.95 0.9485 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H03 mock treatment 18198.4 708.0 0.64 0.6389 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H04 mock treatment 18993.5 1500.0 1.36 1.3569 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H05 mock treatment 18399.9 909.0 0.82 0.8209 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H06 mock treatment 19192.4 1700.0 1.54 1.5365 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H07 mock treatment 18265.9 775.0 0.7 0.6999 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H08 mock treatment 18254.7 764.0 0.69 0.6898 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H09 mock treatment 17365.1 -126.0 -0.11 -0.1135 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H10 mock treatment 17871.7 381.0 0.34 0.3439 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H11 mock treatment 17948.5 458.0 0.41 0.4133 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H12 mock treatment 18042.8 552.0 0.5 0.4984 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H13 mock treatment 17769.4 279.0 0.25 0.2516 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H14 mock treatment 16805.8 -685.0 -0.62 -0.6186 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H15 mock treatment 17779.4 289.0 0.26 0.2606 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H16 mock treatment 18265.4 775.0 0.7 0.6994 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H17 mock treatment 17657.3 166.0 0.15 0.1503 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H18 mock treatment 18090.7 600.0 0.54 0.5417 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H19 mock treatment 18416.8 926.0 0.84 0.8362 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H20 mock treatment 18321.1 830.0 0.75 0.7497 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H21 mock treatment 17193.5 -297.0 -0.27 -0.2685 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H22 mock treatment 18375.3 884.0 0.8 0.7987 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H23 mock treatment 16975.7 -515.0 -0.47 -0.4652 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base H24 mock treatment 15291.5 -2200.0 -1.99 -1.986 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I01 mock treatment 17101.8 -389.0 -0.35 -0.3513 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I02 mock treatment 17873.0 382.0 0.35 0.3451 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I03 mock treatment 17461.2 -29.6 -0.03 -0.0268 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I04 mock treatment 18446.3 955.0 0.86 0.8628 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I05 mock treatment 18229.4 739.0 0.67 0.6669 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I06 mock treatment 18145.3 654.0 0.59 0.591 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I07 mock treatment 16742.9 -748.0 -0.68 -0.6754 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I08 mock treatment 17380.1 -111.0 -0.1 -0.1 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I09 mock treatment 16898.2 -593.0 -0.54 -0.5351 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I10 mock treatment 17364.9 -126.0 -0.11 -0.1137 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I11 mock treatment 17099.5 -391.0 -0.35 -0.3534 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I12 mock treatment 17194.7 -296.0 -0.27 -0.2674 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I13 mock treatment 17545.3 54.5 0.05 0.0492 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I14 mock treatment 15772.1 -1720.0 -1.55 -1.552 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I15 mock treatment 17604.9 114.0 0.1 0.103 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I16 mock treatment 17353.6 -137.0 -0.12 -0.1239 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I17 mock treatment 17755.8 265.0 0.24 0.2393 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I18 mock treatment 17529.2 38.4 0.03 0.0346 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I19 mock treatment 17934.6 444.0 0.4 0.4007 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I20 mock treatment 17747.9 257.0 0.23 0.2321 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I21 mock treatment 17342.1 -149.0 -0.13 -0.1343 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I22 mock treatment 18207.7 717.0 0.65 0.6473 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I23 mock treatment 17710.0 219.0 0.2 0.1979 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base I24 mock treatment 17089.5 -401.0 -0.36 -0.3624 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J01 mock treatment 16820.1 -671.0 -0.61 -0.6057 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J02 mock treatment 18322.5 832.0 0.75 0.751 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J03 mock treatment 18010.7 520.0 0.47 0.4694 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J04 mock treatment 18669.0 1180.0 1.06 1.0639 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J05 mock treatment 18399.6 909.0 0.82 0.8206 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J06 mock treatment 17793.8 303.0 0.27 0.2736 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J07 mock treatment 17749.3 258.0 0.23 0.2334 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J08 mock treatment 17332.5 -158.0 -0.14 -0.143 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J09 mock treatment 17363.9 -127.0 -0.11 -0.1146 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J10 mock treatment 17643.4 153.0 0.14 0.1378 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J11 mock treatment 17676.5 186.0 0.17 0.1677 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J12 mock treatment 17559.0 68.2 0.06 0.0616 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J13 mock treatment 17247.4 -243.0 -0.22 -0.2198 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J14 mock treatment 17818.4 328.0 0.3 0.2958 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J15 mock treatment 17139.6 -351.0 -0.32 -0.3172 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J16 mock treatment 17443.4 -47.4 -0.04 -0.0428 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J17 mock treatment 17490.9 0.0712 0.0 1.0E-4 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J18 mock treatment 16746.4 -744.0 -0.67 -0.6722 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J19 mock treatment 17665.7 175.0 0.16 0.1579 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J20 mock treatment 17738.0 247.0 0.22 0.2232 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J21 mock treatment 17614.3 123.0 0.11 0.1115 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J22 mock treatment 17932.1 441.0 0.4 0.3985 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J23 mock treatment 17367.8 -123.0 -0.11 -0.1111 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base J24 mock treatment 16913.1 -578.0 -0.52 -0.5217 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K01 mock treatment 16606.7 -884.0 -0.8 -0.7984 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K02 mock treatment 17057.3 -434.0 -0.39 -0.3915 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K03 mock treatment 17394.9 -95.9 -0.09 -0.0866 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K04 mock treatment 17455.9 -34.9 -0.03 -0.0315 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K05 mock treatment 18801.3 1310.0 1.18 1.1834 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K06 mock treatment 18084.4 594.0 0.54 0.536 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K07 mock treatment 15808.5 -1680.0 -1.52 -1.5192 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K08 mock treatment 16871.4 -619.0 -0.56 -0.5593 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K09 mock treatment 16952.2 -539.0 -0.49 -0.4864 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K10 mock treatment 16609.3 -882.0 -0.8 -0.796 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K11 mock treatment 16705.2 -786.0 -0.71 -0.7094 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K12 mock treatment 17548.4 57.6 0.05 0.052 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K13 mock treatment 16996.4 -494.0 -0.45 -0.4465 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K14 mock treatment 17585.5 94.7 0.09 0.0855 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K15 mock treatment 16807.1 -684.0 -0.62 -0.6174 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K16 mock treatment 17101.5 -389.0 -0.35 -0.3516 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K17 mock treatment 17194.8 -296.0 -0.27 -0.2673 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K18 mock treatment 16343.9 -1150.0 -1.04 -1.0357 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K19 mock treatment 17310.6 -180.0 -0.16 -0.1627 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K20 mock treatment 17634.9 144.0 0.13 0.1301 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K21 mock treatment 17604.7 114.0 0.1 0.1028 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K22 mock treatment 16919.1 -572.0 -0.52 -0.5163 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K23 mock treatment 17436.9 -53.9 -0.05 -0.0487 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base K24 mock treatment 15578.4 -1910.0 -1.73 -1.7269 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L01 mock treatment 16829.3 -662.0 -0.6 -0.5974 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L02 mock treatment 17497.4 6.57 0.01 0.0059 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L03 mock treatment 17245.3 -246.0 -0.22 -0.2217 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L04 mock treatment 17507.8 17.0 0.02 0.0153 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L05 mock treatment 17994.5 504.0 0.45 0.4548 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L06 mock treatment 16531.1 -960.0 -0.87 -0.8666 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L07 mock treatment 17186.8 -304.0 -0.27 -0.2745 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L08 mock treatment 16552.2 -939.0 -0.85 -0.8476 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L09 mock treatment 17165.6 -325.0 -0.29 -0.2937 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L10 mock treatment 17936.4 446.0 0.4 0.4024 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L11 mock treatment 17537.3 46.5 0.04 0.042 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L12 mock treatment 17755.6 265.0 0.24 0.2391 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L13 mock treatment 17615.3 124.0 0.11 0.1124 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L14 mock treatment 17237.0 -254.0 -0.23 -0.2292 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L15 mock treatment 17382.7 -108.0 -0.1 -0.0976 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L16 mock treatment 17249.4 -241.0 -0.22 -0.218 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L17 mock treatment 17232.4 -258.0 -0.23 -0.2334 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L18 mock treatment 17078.5 -412.0 -0.37 -0.3723 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L19 mock treatment 16851.8 -639.0 -0.58 -0.577 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L20 mock treatment 17664.3 173.0 0.16 0.1566 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L21 mock treatment 17668.6 178.0 0.16 0.1605 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L22 mock treatment 16170.0 -1320.0 -1.19 -1.1927 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L23 mock treatment 17623.3 132.0 0.12 0.1196 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base L24 mock treatment 16225.6 -1270.0 -1.14 -1.1425 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M01 mock treatment 16444.3 -1050.0 -0.95 -0.945 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M02 mock treatment 17428.9 -61.9 -0.06 -0.0559 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M03 mock treatment 17594.0 103.0 0.09 0.0932 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M04 mock treatment 16951.9 -539.0 -0.49 -0.4867 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M05 mock treatment 17320.8 -170.0 -0.15 -0.1535 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M06 mock treatment 15828.7 -1660.0 -1.5 -1.5009 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M07 mock treatment 17309.0 -182.0 -0.16 -0.1642 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M08 mock treatment 17157.1 -334.0 -0.3 -0.3014 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M09 mock treatment 16988.9 -502.0 -0.45 -0.4532 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M10 mock treatment 17937.8 447.0 0.4 0.4036 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M11 mock treatment 16072.8 -1420.0 -1.28 -1.2805 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M12 mock treatment 17741.6 251.0 0.23 0.2264 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M13 mock treatment 17583.2 92.4 0.08 0.0834 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M14 mock treatment 18267.7 777.0 0.7 0.7015 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M15 mock treatment 17631.7 141.0 0.13 0.1272 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M16 mock treatment 17038.4 -452.0 -0.41 -0.4085 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M17 mock treatment 17115.4 -375.0 -0.34 -0.339 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M18 mock treatment 16918.3 -573.0 -0.52 -0.517 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M19 mock treatment 17026.5 -464.0 -0.42 -0.4193 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M20 mock treatment 16421.3 -1070.0 -0.97 -0.9658 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M21 mock treatment 17691.3 200.0 0.18 0.181 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M22 mock treatment 15923.2 -1570.0 -1.42 -1.4156 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M23 mock treatment 17050.1 -441.0 -0.4 -0.398 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base M24 mock treatment 16305.3 -1190.0 -1.07 -1.0705 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N01 mock treatment 16678.2 -813.0 -0.73 -0.7338 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N02 mock treatment 17843.8 353.0 0.32 0.3187 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N03 mock treatment 17206.2 -285.0 -0.26 -0.257 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N04 mock treatment 16995.4 -495.0 -0.45 -0.4474 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N05 mock treatment 16920.6 -570.0 -0.51 -0.5149 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N06 mock treatment 16579.1 -912.0 -0.82 -0.8233 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N07 mock treatment 17107.9 -383.0 -0.35 -0.3458 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N08 mock treatment 17707.3 216.0 0.2 0.1955 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N09 mock treatment 16621.4 -869.0 -0.79 -0.7851 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N10 mock treatment 18153.1 662.0 0.6 0.598 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N11 mock treatment 15165.6 -2330.0 -2.1 -2.0997 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N12 mock treatment 17968.4 478.0 0.43 0.4313 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N13 mock treatment 16883.2 -608.0 -0.55 -0.5487 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N14 mock treatment 18078.8 588.0 0.53 0.5309 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N15 mock treatment 16444.6 -1050.0 -0.94 -0.9448 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N16 mock treatment 16500.8 -990.0 -0.89 -0.894 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N17 mock treatment 16274.3 -1220.0 -1.1 -1.0985 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N18 mock treatment 16889.2 -602.0 -0.54 -0.5433 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N19 mock treatment 14826.5 -2660.0 -2.41 -2.4059 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N20 mock treatment 17247.0 -244.0 -0.22 -0.2202 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N21 mock treatment 17657.0 166.0 0.15 0.1501 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N22 mock treatment 17294.5 -196.0 -0.18 -0.1773 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N23 mock treatment 17402.0 -88.8 -0.08 -0.0802 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base N24 mock treatment 16811.3 -680.0 -0.61 -0.6136 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O01 mock treatment 16843.6 -647.0 -0.58 -0.5845 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O02 mock treatment 17564.5 73.7 0.07 0.0665 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O03 mock treatment 17379.0 -112.0 -0.1 -0.101 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O04 mock treatment 17778.6 288.0 0.26 0.2599 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O05 mock treatment 16791.6 -699.0 -0.63 -0.6314 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O06 mock treatment 15381.9 -2110.0 -1.9 -1.9044 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O07 mock treatment 16160.8 -1330.0 -1.2 -1.201 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O08 mock treatment 16667.4 -823.0 -0.74 -0.7436 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O09 mock treatment 16017.7 -1470.0 -1.33 -1.3302 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O10 mock treatment 17228.2 -263.0 -0.24 -0.2372 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O11 mock treatment 16725.2 -766.0 -0.69 -0.6914 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O12 mock treatment 18052.8 562.0 0.51 0.5075 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O13 mock treatment 17632.4 142.0 0.13 0.1278 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O14 mock treatment 18427.7 937.0 0.85 0.846 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O15 mock treatment 15464.5 -2030.0 -1.83 -1.8298 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O16 mock treatment 16584.6 -906.0 -0.82 -0.8183 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O17 mock treatment 16535.7 -955.0 -0.86 -0.8625 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O18 mock treatment 16519.0 -972.0 -0.88 -0.8776 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O19 mock treatment 16028.3 -1460.0 -1.32 -1.3207 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O20 mock treatment 17241.0 -250.0 -0.23 -0.2256 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O21 mock treatment 16960.6 -530.0 -0.48 -0.4788 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O22 mock treatment 16345.1 -1150.0 -1.03 -1.0346 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O23 mock treatment 17151.4 -339.0 -0.31 -0.3065 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base O24 mock treatment 17060.1 -431.0 -0.39 -0.389 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P01 mock treatment 16810.0 -681.0 -0.61 -0.6148 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P02 mock treatment 17936.2 445.0 0.4 0.4022 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P03 mock treatment 17263.1 -228.0 -0.21 -0.2056 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P04 mock treatment 17550.0 59.2 0.05 0.0534 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P05 mock treatment 16787.5 -703.0 -0.64 -0.6351 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P06 mock treatment 17750.8 260.0 0.23 0.2348 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P07 mock treatment 16067.1 -1420.0 -1.29 -1.2856 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P08 mock treatment 17782.2 291.0 0.26 0.2631 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P09 mock treatment 16736.5 -754.0 -0.68 -0.6812 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P10 mock treatment 14926.1 -2560.0 -2.32 -2.316 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P11 mock treatment 17246.8 -244.0 -0.22 -0.2204 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P12 mock treatment 17865.7 375.0 0.34 0.3385 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P13 mock treatment 18178.4 688.0 0.62 0.6209 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P14 mock treatment 17183.8 -307.0 -0.28 -0.2772 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P15 mock treatment 16738.1 -753.0 -0.68 -0.6797 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P16 mock treatment 17060.0 -431.0 -0.39 -0.389 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P17 mock treatment 17441.5 -49.3 -0.04 -0.0445 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P18 mock treatment 17058.3 -433.0 -0.39 -0.3906 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P19 mock treatment 17583.0 92.2 0.08 0.0832 1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P20 mock treatment 16696.1 -795.0 -0.72 -0.7176 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P21 mock treatment 17315.0 -176.0 -0.16 -0.1588 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P22 mock treatment 15906.2 -1580.0 -1.43 -1.4309 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P23 mock treatment 16594.0 -897.0 -0.81 -0.8098 -1.0 1037.0008 pChk1AvNucInt(1037.0008) DNADamageImagingScreen 1037.0008.Base P24 mock treatment 16670.0 -821.0 -0.74 -0.7412 -1.0